BLASTP 2.2.25+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.



Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
           15,229,318 sequences; 5,219,829,388 total letters



Query= Rv2846c

Length=530
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

gi|15609983|ref|NP_217362.1|  integral membrane efflux protein Ef...  1046    0.0   
gi|289571034|ref|ZP_06451261.1|  membrane efflux protein efpA [My...  1045    0.0   
gi|31794023|ref|NP_856516.1|  integral membrane efflux protein Ef...  1044    0.0   
gi|66737273|gb|AAY54548.1|  mutant EfpA [Mycobacterium tuberculosis]  1044    0.0   
gi|340627839|ref|YP_004746291.1|  putative integral membrane effl...  1043    0.0   
gi|1161051|gb|AAA85344.1|  efflux protein [Mycobacterium tubercul...   986    0.0   
gi|339295687|gb|AEJ47798.1|  integral membrane efflux protein Efp...   917    0.0   
gi|183981900|ref|YP_001850191.1|  integral membrane efflux protei...   890    0.0   
gi|118617675|ref|YP_906007.1|  integral membrane efflux protein E...   885    0.0   
gi|342858322|ref|ZP_08714977.1|  transporter, major facilitator f...   885    0.0   
gi|41409013|ref|NP_961849.1|  EfpA_2 [Mycobacterium avium subsp. ...   880    0.0   
gi|240172753|ref|ZP_04751412.1|  integral membrane efflux protein...   872    0.0   
gi|296171595|ref|ZP_06852835.1|  efflux protein [Mycobacterium pa...   870    0.0   
gi|289444397|ref|ZP_06434141.1|  membrane efflux protein efpA [My...   869    0.0   
gi|254819681|ref|ZP_05224682.1|  transporter, major facilitator f...   852    0.0   
gi|254776132|ref|ZP_05217648.1|  transporter, major facilitator f...   843    0.0   
gi|15827823|ref|NP_302086.1|  transmembrane efflux protein [Mycob...   834    0.0   
gi|145224626|ref|YP_001135304.1|  EmrB/QacA family drug resistanc...   747    0.0   
gi|315444958|ref|YP_004077837.1|  drug resistance transporter Emr...   746    0.0   
gi|120403297|ref|YP_953126.1|  major facilitator superfamily tran...   746    0.0   
gi|108799042|ref|YP_639239.1|  major facilitator transporter [Myc...   728    0.0   
gi|333991210|ref|YP_004523824.1|  integral membrane efflux protei...   712    0.0   
gi|118471791|ref|YP_886956.1|  efflux protein [Mycobacterium smeg...   687    0.0   
gi|254819676|ref|ZP_05224677.1|  EfpA_1 [Mycobacterium intracellu...   592    7e-167
gi|342859837|ref|ZP_08716490.1|  EfpA_1 [Mycobacterium colombiens...   575    6e-162
gi|336462020|gb|EGO40869.1|  arabinose efflux permease family pro...   573    2e-161
gi|41407966|ref|NP_960802.1|  EfpA_1 [Mycobacterium avium subsp. ...   573    2e-161
gi|118467314|ref|YP_881570.1|  transporter, major facilitator fam...   568    1e-159
gi|254775040|ref|ZP_05216556.1|  transporter, major facilitator f...   568    1e-159
gi|289448508|ref|ZP_06438252.1|  membrane efflux protein efpA [My...   560    2e-157
gi|169630224|ref|YP_001703873.1|  putative transmembrane efflux p...   559    4e-157
gi|120403298|ref|YP_953127.1|  major facilitator superfamily tran...   517    2e-144
gi|226366063|ref|YP_002783846.1|  MFS transporter [Rhodococcus op...   442    9e-122
gi|111023577|ref|YP_706549.1|  major facilitator superfamily mult...   439    4e-121
gi|226306098|ref|YP_002766058.1|  drug resistance efflux protein ...   432    6e-119
gi|229491343|ref|ZP_04385167.1|  multidrug transporter, MFS famil...   432    1e-118
gi|325673401|ref|ZP_08153092.1|  efflux protein [Rhodococcus equi...   404    2e-110
gi|312139293|ref|YP_004006629.1|  mfs transporter [Rhodococcus eq...   404    2e-110
gi|333919283|ref|YP_004492864.1|  putative MFS transporter [Amyco...   393    4e-107
gi|262202078|ref|YP_003273286.1|  EmrB/QacA subfamily drug resist...   382    1e-103
gi|296139418|ref|YP_003646661.1|  EmrB/QacA subfamily drug resist...   380    5e-103
gi|343926761|ref|ZP_08766258.1|  putative major facilitator super...   378    1e-102
gi|317508516|ref|ZP_07966183.1|  major facilitator superfamily tr...   363    4e-98 
gi|296139419|ref|YP_003646662.1|  major facilitator superfamily p...   354    2e-95 
gi|54026047|ref|YP_120289.1|  putative transporter [Nocardia farc...   346    5e-93 
gi|296394269|ref|YP_003659153.1|  major facilitator superfamily p...   345    1e-92 
gi|227488646|ref|ZP_03918962.1|  major facilitator superfamily mu...   316    6e-84 
gi|227543249|ref|ZP_03973298.1|  major facilitator superfamily mu...   315    2e-83 
gi|158317950|ref|YP_001510458.1|  EmrB/QacA family drug resistanc...   273    5e-71 
gi|328885854|emb|CCA59093.1|  MFS family multidrug efflux protein...   269    1e-69 


>gi|15609983|ref|NP_217362.1| integral membrane efflux protein EfpA [Mycobacterium tuberculosis 
H37Rv]
 gi|15842387|ref|NP_337424.1| efflux protein [Mycobacterium tuberculosis CDC1551]
 gi|148662687|ref|YP_001284210.1| efflux protein [Mycobacterium tuberculosis H37Ra]
 62 more sequence titles
 Length=530

 Score = 1046 bits (2706),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 530/530 (100%), Positives = 530/530 (100%), Gaps = 0/530 (0%)

Query  1    MTALNDTERAVRNWTAGRPHRPAPMRPPRSEETASERPSRYYPTWLPSRSFIAAVIAIGG  60
            MTALNDTERAVRNWTAGRPHRPAPMRPPRSEETASERPSRYYPTWLPSRSFIAAVIAIGG
Sbjct  1    MTALNDTERAVRNWTAGRPHRPAPMRPPRSEETASERPSRYYPTWLPSRSFIAAVIAIGG  60

Query  61   MQLLATMDSTVAIVALPKIQNELSLSDAGRSWVITAYVLTFGGLMLLGGRLGDTIGRKRT  120
            MQLLATMDSTVAIVALPKIQNELSLSDAGRSWVITAYVLTFGGLMLLGGRLGDTIGRKRT
Sbjct  61   MQLLATMDSTVAIVALPKIQNELSLSDAGRSWVITAYVLTFGGLMLLGGRLGDTIGRKRT  120

Query  121  FIVGVALFTISSVLCAVAWDEATLVIARLSQGVGSAIASPTGLALVATTFPKGPARNAAT  180
            FIVGVALFTISSVLCAVAWDEATLVIARLSQGVGSAIASPTGLALVATTFPKGPARNAAT
Sbjct  121  FIVGVALFTISSVLCAVAWDEATLVIARLSQGVGSAIASPTGLALVATTFPKGPARNAAT  180

Query  181  AVFAAMTAIGSVMGLVVGGALTEVSWRWAFLVNVPIGLVMIYLARTALRETNKERMKLDA  240
            AVFAAMTAIGSVMGLVVGGALTEVSWRWAFLVNVPIGLVMIYLARTALRETNKERMKLDA
Sbjct  181  AVFAAMTAIGSVMGLVVGGALTEVSWRWAFLVNVPIGLVMIYLARTALRETNKERMKLDA  240

Query  241  TGAILATLACTAAVFAFSIGPEKGWMSGITIGSGLVALAAAVAFVIVERTAENPVVPFHL  300
            TGAILATLACTAAVFAFSIGPEKGWMSGITIGSGLVALAAAVAFVIVERTAENPVVPFHL
Sbjct  241  TGAILATLACTAAVFAFSIGPEKGWMSGITIGSGLVALAAAVAFVIVERTAENPVVPFHL  300

Query  301  FRDRNRLVTFSAILLAGGVMFSLTVCIGLYVQDILGYSALRAGVGFIPFVIAMGIGLGVS  360
            FRDRNRLVTFSAILLAGGVMFSLTVCIGLYVQDILGYSALRAGVGFIPFVIAMGIGLGVS
Sbjct  301  FRDRNRLVTFSAILLAGGVMFSLTVCIGLYVQDILGYSALRAGVGFIPFVIAMGIGLGVS  360

Query  361  SQLVSRFSPRVLTIGGGYLLFGAMLYGSFFMHRGVPYFPNLVMPIVVGGIGIGMAVVPLT  420
            SQLVSRFSPRVLTIGGGYLLFGAMLYGSFFMHRGVPYFPNLVMPIVVGGIGIGMAVVPLT
Sbjct  361  SQLVSRFSPRVLTIGGGYLLFGAMLYGSFFMHRGVPYFPNLVMPIVVGGIGIGMAVVPLT  420

Query  421  LSAIAGVGFDQIGPVSAIALMLQSLGGPLVLAVIQAVITSRTLYLGGTTGPVKFMNDVQL  480
            LSAIAGVGFDQIGPVSAIALMLQSLGGPLVLAVIQAVITSRTLYLGGTTGPVKFMNDVQL
Sbjct  421  LSAIAGVGFDQIGPVSAIALMLQSLGGPLVLAVIQAVITSRTLYLGGTTGPVKFMNDVQL  480

Query  481  AALDHAYTYGLLWVAGAAIIVGGMALFIGYTPQQVAHAQEVKEAIDAGEL  530
            AALDHAYTYGLLWVAGAAIIVGGMALFIGYTPQQVAHAQEVKEAIDAGEL
Sbjct  481  AALDHAYTYGLLWVAGAAIIVGGMALFIGYTPQQVAHAQEVKEAIDAGEL  530


>gi|289571034|ref|ZP_06451261.1| membrane efflux protein efpA [Mycobacterium tuberculosis T17]
 gi|289751507|ref|ZP_06510885.1| membrane efflux protein efpA [Mycobacterium tuberculosis T92]
 gi|289544788|gb|EFD48436.1| membrane efflux protein efpA [Mycobacterium tuberculosis T17]
 gi|289692094|gb|EFD59523.1| membrane efflux protein efpA [Mycobacterium tuberculosis T92]
Length=530

 Score = 1045 bits (2701),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 529/530 (99%), Positives = 529/530 (99%), Gaps = 0/530 (0%)

Query  1    MTALNDTERAVRNWTAGRPHRPAPMRPPRSEETASERPSRYYPTWLPSRSFIAAVIAIGG  60
            MTALNDTERAVRNWTAGRPHRPAPMRPPRSEETASERPSRYYPTWLPSRSFIAAVIAIGG
Sbjct  1    MTALNDTERAVRNWTAGRPHRPAPMRPPRSEETASERPSRYYPTWLPSRSFIAAVIAIGG  60

Query  61   MQLLATMDSTVAIVALPKIQNELSLSDAGRSWVITAYVLTFGGLMLLGGRLGDTIGRKRT  120
            MQLLATMDSTVA VALPKIQNELSLSDAGRSWVITAYVLTFGGLMLLGGRLGDTIGRKRT
Sbjct  61   MQLLATMDSTVATVALPKIQNELSLSDAGRSWVITAYVLTFGGLMLLGGRLGDTIGRKRT  120

Query  121  FIVGVALFTISSVLCAVAWDEATLVIARLSQGVGSAIASPTGLALVATTFPKGPARNAAT  180
            FIVGVALFTISSVLCAVAWDEATLVIARLSQGVGSAIASPTGLALVATTFPKGPARNAAT
Sbjct  121  FIVGVALFTISSVLCAVAWDEATLVIARLSQGVGSAIASPTGLALVATTFPKGPARNAAT  180

Query  181  AVFAAMTAIGSVMGLVVGGALTEVSWRWAFLVNVPIGLVMIYLARTALRETNKERMKLDA  240
            AVFAAMTAIGSVMGLVVGGALTEVSWRWAFLVNVPIGLVMIYLARTALRETNKERMKLDA
Sbjct  181  AVFAAMTAIGSVMGLVVGGALTEVSWRWAFLVNVPIGLVMIYLARTALRETNKERMKLDA  240

Query  241  TGAILATLACTAAVFAFSIGPEKGWMSGITIGSGLVALAAAVAFVIVERTAENPVVPFHL  300
            TGAILATLACTAAVFAFSIGPEKGWMSGITIGSGLVALAAAVAFVIVERTAENPVVPFHL
Sbjct  241  TGAILATLACTAAVFAFSIGPEKGWMSGITIGSGLVALAAAVAFVIVERTAENPVVPFHL  300

Query  301  FRDRNRLVTFSAILLAGGVMFSLTVCIGLYVQDILGYSALRAGVGFIPFVIAMGIGLGVS  360
            FRDRNRLVTFSAILLAGGVMFSLTVCIGLYVQDILGYSALRAGVGFIPFVIAMGIGLGVS
Sbjct  301  FRDRNRLVTFSAILLAGGVMFSLTVCIGLYVQDILGYSALRAGVGFIPFVIAMGIGLGVS  360

Query  361  SQLVSRFSPRVLTIGGGYLLFGAMLYGSFFMHRGVPYFPNLVMPIVVGGIGIGMAVVPLT  420
            SQLVSRFSPRVLTIGGGYLLFGAMLYGSFFMHRGVPYFPNLVMPIVVGGIGIGMAVVPLT
Sbjct  361  SQLVSRFSPRVLTIGGGYLLFGAMLYGSFFMHRGVPYFPNLVMPIVVGGIGIGMAVVPLT  420

Query  421  LSAIAGVGFDQIGPVSAIALMLQSLGGPLVLAVIQAVITSRTLYLGGTTGPVKFMNDVQL  480
            LSAIAGVGFDQIGPVSAIALMLQSLGGPLVLAVIQAVITSRTLYLGGTTGPVKFMNDVQL
Sbjct  421  LSAIAGVGFDQIGPVSAIALMLQSLGGPLVLAVIQAVITSRTLYLGGTTGPVKFMNDVQL  480

Query  481  AALDHAYTYGLLWVAGAAIIVGGMALFIGYTPQQVAHAQEVKEAIDAGEL  530
            AALDHAYTYGLLWVAGAAIIVGGMALFIGYTPQQVAHAQEVKEAIDAGEL
Sbjct  481  AALDHAYTYGLLWVAGAAIIVGGMALFIGYTPQQVAHAQEVKEAIDAGEL  530


>gi|31794023|ref|NP_856516.1| integral membrane efflux protein EfpA [Mycobacterium bovis AF2122/97]
 gi|121638726|ref|YP_978950.1| putative integral membrane efflux protein efpA [Mycobacterium 
bovis BCG str. Pasteur 1173P2]
 gi|224991218|ref|YP_002645907.1| putative integral membrane efflux protein [Mycobacterium bovis 
BCG str. Tokyo 172]
 gi|31619617|emb|CAD95056.1| POSSIBLE INTEGRAL MEMBRANE EFFLUX PROTEIN EFPA [Mycobacterium 
bovis AF2122/97]
 gi|121494374|emb|CAL72855.1| Possible integral membrane efflux protein efpA [Mycobacterium 
bovis BCG str. Pasteur 1173P2]
 gi|224774333|dbj|BAH27139.1| putative integral membrane efflux protein [Mycobacterium bovis 
BCG str. Tokyo 172]
 gi|341602764|emb|CCC65442.1| possible integral membrane efflux protein efpA [Mycobacterium 
bovis BCG str. Moreau RDJ]
Length=530

 Score = 1044 bits (2700),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 529/530 (99%), Positives = 529/530 (99%), Gaps = 0/530 (0%)

Query  1    MTALNDTERAVRNWTAGRPHRPAPMRPPRSEETASERPSRYYPTWLPSRSFIAAVIAIGG  60
            MTALNDTERAVRNW AGRPHRPAPMRPPRSEETASERPSRYYPTWLPSRSFIAAVIAIGG
Sbjct  1    MTALNDTERAVRNWRAGRPHRPAPMRPPRSEETASERPSRYYPTWLPSRSFIAAVIAIGG  60

Query  61   MQLLATMDSTVAIVALPKIQNELSLSDAGRSWVITAYVLTFGGLMLLGGRLGDTIGRKRT  120
            MQLLATMDSTVAIVALPKIQNELSLSDAGRSWVITAYVLTFGGLMLLGGRLGDTIGRKRT
Sbjct  61   MQLLATMDSTVAIVALPKIQNELSLSDAGRSWVITAYVLTFGGLMLLGGRLGDTIGRKRT  120

Query  121  FIVGVALFTISSVLCAVAWDEATLVIARLSQGVGSAIASPTGLALVATTFPKGPARNAAT  180
            FIVGVALFTISSVLCAVAWDEATLVIARLSQGVGSAIASPTGLALVATTFPKGPARNAAT
Sbjct  121  FIVGVALFTISSVLCAVAWDEATLVIARLSQGVGSAIASPTGLALVATTFPKGPARNAAT  180

Query  181  AVFAAMTAIGSVMGLVVGGALTEVSWRWAFLVNVPIGLVMIYLARTALRETNKERMKLDA  240
            AVFAAMTAIGSVMGLVVGGALTEVSWRWAFLVNVPIGLVMIYLARTALRETNKERMKLDA
Sbjct  181  AVFAAMTAIGSVMGLVVGGALTEVSWRWAFLVNVPIGLVMIYLARTALRETNKERMKLDA  240

Query  241  TGAILATLACTAAVFAFSIGPEKGWMSGITIGSGLVALAAAVAFVIVERTAENPVVPFHL  300
            TGAILATLACTAAVFAFSIGPEKGWMSGITIGSGLVALAAAVAFVIVERTAENPVVPFHL
Sbjct  241  TGAILATLACTAAVFAFSIGPEKGWMSGITIGSGLVALAAAVAFVIVERTAENPVVPFHL  300

Query  301  FRDRNRLVTFSAILLAGGVMFSLTVCIGLYVQDILGYSALRAGVGFIPFVIAMGIGLGVS  360
            FRDRNRLVTFSAILLAGGVMFSLTVCIGLYVQDILGYSALRAGVGFIPFVIAMGIGLGVS
Sbjct  301  FRDRNRLVTFSAILLAGGVMFSLTVCIGLYVQDILGYSALRAGVGFIPFVIAMGIGLGVS  360

Query  361  SQLVSRFSPRVLTIGGGYLLFGAMLYGSFFMHRGVPYFPNLVMPIVVGGIGIGMAVVPLT  420
            SQLVSRFSPRVLTIGGGYLLFGAMLYGSFFMHRGVPYFPNLVMPIVVGGIGIGMAVVPLT
Sbjct  361  SQLVSRFSPRVLTIGGGYLLFGAMLYGSFFMHRGVPYFPNLVMPIVVGGIGIGMAVVPLT  420

Query  421  LSAIAGVGFDQIGPVSAIALMLQSLGGPLVLAVIQAVITSRTLYLGGTTGPVKFMNDVQL  480
            LSAIAGVGFDQIGPVSAIALMLQSLGGPLVLAVIQAVITSRTLYLGGTTGPVKFMNDVQL
Sbjct  421  LSAIAGVGFDQIGPVSAIALMLQSLGGPLVLAVIQAVITSRTLYLGGTTGPVKFMNDVQL  480

Query  481  AALDHAYTYGLLWVAGAAIIVGGMALFIGYTPQQVAHAQEVKEAIDAGEL  530
            AALDHAYTYGLLWVAGAAIIVGGMALFIGYTPQQVAHAQEVKEAIDAGEL
Sbjct  481  AALDHAYTYGLLWVAGAAIIVGGMALFIGYTPQQVAHAQEVKEAIDAGEL  530


>gi|66737273|gb|AAY54548.1| mutant EfpA [Mycobacterium tuberculosis]
Length=530

 Score = 1044 bits (2699),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 529/530 (99%), Positives = 529/530 (99%), Gaps = 0/530 (0%)

Query  1    MTALNDTERAVRNWTAGRPHRPAPMRPPRSEETASERPSRYYPTWLPSRSFIAAVIAIGG  60
            MTALNDTERAVRNWTAGRPHRPAPMRPPRSEETASERPSRYYPTWLPSRSFIAAVIAIGG
Sbjct  1    MTALNDTERAVRNWTAGRPHRPAPMRPPRSEETASERPSRYYPTWLPSRSFIAAVIAIGG  60

Query  61   MQLLATMDSTVAIVALPKIQNELSLSDAGRSWVITAYVLTFGGLMLLGGRLGDTIGRKRT  120
            MQLLATMDSTVAIVALPKIQNELSLSDAGRSWVITAYVLTFGGLMLLGGRLGDTIGRKRT
Sbjct  61   MQLLATMDSTVAIVALPKIQNELSLSDAGRSWVITAYVLTFGGLMLLGGRLGDTIGRKRT  120

Query  121  FIVGVALFTISSVLCAVAWDEATLVIARLSQGVGSAIASPTGLALVATTFPKGPARNAAT  180
            FIVGVALFTISSVLCAVAWDEATLVIARLSQGVGSAIASPTGLALVATTFPKGPARNAAT
Sbjct  121  FIVGVALFTISSVLCAVAWDEATLVIARLSQGVGSAIASPTGLALVATTFPKGPARNAAT  180

Query  181  AVFAAMTAIGSVMGLVVGGALTEVSWRWAFLVNVPIGLVMIYLARTALRETNKERMKLDA  240
            AVFAAMTAIGSVMGLVVGGALTEVSWRWAFLVNVPIGLVMIYLARTALRETNKERMKLDA
Sbjct  181  AVFAAMTAIGSVMGLVVGGALTEVSWRWAFLVNVPIGLVMIYLARTALRETNKERMKLDA  240

Query  241  TGAILATLACTAAVFAFSIGPEKGWMSGITIGSGLVALAAAVAFVIVERTAENPVVPFHL  300
            TGAILATLACTAAVFAFSIGPEKGWMSGITIGSGLVALAAAVAFVIVERTAENPVVPFHL
Sbjct  241  TGAILATLACTAAVFAFSIGPEKGWMSGITIGSGLVALAAAVAFVIVERTAENPVVPFHL  300

Query  301  FRDRNRLVTFSAILLAGGVMFSLTVCIGLYVQDILGYSALRAGVGFIPFVIAMGIGLGVS  360
            FRDRNRLVTFSAILLAGGVMFSLTVCIGLYVQDILGYSALRAGVGFIPFVIAMGIGLGVS
Sbjct  301  FRDRNRLVTFSAILLAGGVMFSLTVCIGLYVQDILGYSALRAGVGFIPFVIAMGIGLGVS  360

Query  361  SQLVSRFSPRVLTIGGGYLLFGAMLYGSFFMHRGVPYFPNLVMPIVVGGIGIGMAVVPLT  420
            SQLVSRFSPRVLTIGGGYLLFGAMLYGSFFMHRGVPYFPNLVMPIVVGGIGIGMAVVPLT
Sbjct  361  SQLVSRFSPRVLTIGGGYLLFGAMLYGSFFMHRGVPYFPNLVMPIVVGGIGIGMAVVPLT  420

Query  421  LSAIAGVGFDQIGPVSAIALMLQSLGGPLVLAVIQAVITSRTLYLGGTTGPVKFMNDVQL  480
            LSAIAGVGFDQIGPVSAIALMLQSLGGPLVLAVIQAVITSRTLYLGGTTGPVKFMNDVQL
Sbjct  421  LSAIAGVGFDQIGPVSAIALMLQSLGGPLVLAVIQAVITSRTLYLGGTTGPVKFMNDVQL  480

Query  481  AALDHAYTYGLLWVAGAAIIVGGMALFIGYTPQQVAHAQEVKEAIDAGEL  530
            AALDHAYTYGLLWVAGAAIIVGGMALFIGYTPQQVAHAQ VKEAIDAGEL
Sbjct  481  AALDHAYTYGLLWVAGAAIIVGGMALFIGYTPQQVAHAQVVKEAIDAGEL  530


>gi|340627839|ref|YP_004746291.1| putative integral membrane efflux protein EFPA [Mycobacterium 
canettii CIPT 140010059]
 gi|340006029|emb|CCC45199.1| putative integral membrane efflux protein EFPA [Mycobacterium 
canettii CIPT 140010059]
Length=530

 Score = 1043 bits (2698),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 529/530 (99%), Positives = 529/530 (99%), Gaps = 0/530 (0%)

Query  1    MTALNDTERAVRNWTAGRPHRPAPMRPPRSEETASERPSRYYPTWLPSRSFIAAVIAIGG  60
            MTALNDTERAVRNWTAGRP RPAPMRPPRSEETASERPSRYYPTWLPSRSFIAAVIAIGG
Sbjct  1    MTALNDTERAVRNWTAGRPQRPAPMRPPRSEETASERPSRYYPTWLPSRSFIAAVIAIGG  60

Query  61   MQLLATMDSTVAIVALPKIQNELSLSDAGRSWVITAYVLTFGGLMLLGGRLGDTIGRKRT  120
            MQLLATMDSTVAIVALPKIQNELSLSDAGRSWVITAYVLTFGGLMLLGGRLGDTIGRKRT
Sbjct  61   MQLLATMDSTVAIVALPKIQNELSLSDAGRSWVITAYVLTFGGLMLLGGRLGDTIGRKRT  120

Query  121  FIVGVALFTISSVLCAVAWDEATLVIARLSQGVGSAIASPTGLALVATTFPKGPARNAAT  180
            FIVGVALFTISSVLCAVAWDEATLVIARLSQGVGSAIASPTGLALVATTFPKGPARNAAT
Sbjct  121  FIVGVALFTISSVLCAVAWDEATLVIARLSQGVGSAIASPTGLALVATTFPKGPARNAAT  180

Query  181  AVFAAMTAIGSVMGLVVGGALTEVSWRWAFLVNVPIGLVMIYLARTALRETNKERMKLDA  240
            AVFAAMTAIGSVMGLVVGGALTEVSWRWAFLVNVPIGLVMIYLARTALRETNKERMKLDA
Sbjct  181  AVFAAMTAIGSVMGLVVGGALTEVSWRWAFLVNVPIGLVMIYLARTALRETNKERMKLDA  240

Query  241  TGAILATLACTAAVFAFSIGPEKGWMSGITIGSGLVALAAAVAFVIVERTAENPVVPFHL  300
            TGAILATLACTAAVFAFSIGPEKGWMSGITIGSGLVALAAAVAFVIVERTAENPVVPFHL
Sbjct  241  TGAILATLACTAAVFAFSIGPEKGWMSGITIGSGLVALAAAVAFVIVERTAENPVVPFHL  300

Query  301  FRDRNRLVTFSAILLAGGVMFSLTVCIGLYVQDILGYSALRAGVGFIPFVIAMGIGLGVS  360
            FRDRNRLVTFSAILLAGGVMFSLTVCIGLYVQDILGYSALRAGVGFIPFVIAMGIGLGVS
Sbjct  301  FRDRNRLVTFSAILLAGGVMFSLTVCIGLYVQDILGYSALRAGVGFIPFVIAMGIGLGVS  360

Query  361  SQLVSRFSPRVLTIGGGYLLFGAMLYGSFFMHRGVPYFPNLVMPIVVGGIGIGMAVVPLT  420
            SQLVSRFSPRVLTIGGGYLLFGAMLYGSFFMHRGVPYFPNLVMPIVVGGIGIGMAVVPLT
Sbjct  361  SQLVSRFSPRVLTIGGGYLLFGAMLYGSFFMHRGVPYFPNLVMPIVVGGIGIGMAVVPLT  420

Query  421  LSAIAGVGFDQIGPVSAIALMLQSLGGPLVLAVIQAVITSRTLYLGGTTGPVKFMNDVQL  480
            LSAIAGVGFDQIGPVSAIALMLQSLGGPLVLAVIQAVITSRTLYLGGTTGPVKFMNDVQL
Sbjct  421  LSAIAGVGFDQIGPVSAIALMLQSLGGPLVLAVIQAVITSRTLYLGGTTGPVKFMNDVQL  480

Query  481  AALDHAYTYGLLWVAGAAIIVGGMALFIGYTPQQVAHAQEVKEAIDAGEL  530
            AALDHAYTYGLLWVAGAAIIVGGMALFIGYTPQQVAHAQEVKEAIDAGEL
Sbjct  481  AALDHAYTYGLLWVAGAAIIVGGMALFIGYTPQQVAHAQEVKEAIDAGEL  530


>gi|1161051|gb|AAA85344.1| efflux protein [Mycobacterium tuberculosis H37Rv]
Length=529

 Score =  986 bits (2549),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 526/530 (99%), Positives = 527/530 (99%), Gaps = 1/530 (0%)

Query  1    MTALNDTERAVRNWTAGRPHRPAPMRPPRSEETASERPSRYYPTWLPSRSFIAAVIAIGG  60
            MTALNDTERAVRNWTAGRPHRPAPMRPPRSEETASERPSRYYPTWLPSR+FIAAVIAIGG
Sbjct  1    MTALNDTERAVRNWTAGRPHRPAPMRPPRSEETASERPSRYYPTWLPSRTFIAAVIAIGG  60

Query  61   MQLLATMDSTVAIVALPKIQNELSLSDAGRSWVITAYVLTFGGLMLLGGRLGDTIGRKRT  120
            MQLLATMDSTVAIVALPKIQNELSLSDAGRSWVITAYVLTFGGLMLLGGRLGDTIGRKRT
Sbjct  61   MQLLATMDSTVAIVALPKIQNELSLSDAGRSWVITAYVLTFGGLMLLGGRLGDTIGRKRT  120

Query  121  FIVGVALFTISSVLCAVAWDEATLVIARLSQGVGSAIASPTGLALVATTFPKGPARNAAT  180
            FIVGVALFTISSVLCAVAWDEATLVIARLSQGVGSAIASPTGLALVATTFPKGPARNAAT
Sbjct  121  FIVGVALFTISSVLCAVAWDEATLVIARLSQGVGSAIASPTGLALVATTFPKGPARNAAT  180

Query  181  AVFAAMTAIGSVMGLVVGGALTEVSWRWAFLVNVPIGLVMIYLARTALRETNKERMKLDA  240
            AVFAAMTAIGSVMGLVVGG LTEVSWRWAFLVNVPIGLVMIYLARTALRETNKERMKLDA
Sbjct  181  AVFAAMTAIGSVMGLVVGGRLTEVSWRWAFLVNVPIGLVMIYLARTALRETNKERMKLDA  240

Query  241  TGAILATLACTAAVFAFSIGPEKGWMSGITIGSGLVALAAAVAFVIVERTAENPVVPFHL  300
            TGAILATLACTAAVFAFSIGPEKGWMSGITIGSGLVALAAAVAFVIVERTAENPVVPFHL
Sbjct  241  TGAILATLACTAAVFAFSIGPEKGWMSGITIGSGLVALAAAVAFVIVERTAENPVVPFHL  300

Query  301  FRDRNRLVTFSAILLAGGVMFSLTVCIGLYVQDILGYSALRAGVGFIPFVIAMGIGLGVS  360
            FRDRNRLVTFSAILLAGGVMFSLTVCIGLYVQDILGYSALR  VGFIPFVIAMGIGLGVS
Sbjct  301  FRDRNRLVTFSAILLAGGVMFSLTVCIGLYVQDILGYSALRR-VGFIPFVIAMGIGLGVS  359

Query  361  SQLVSRFSPRVLTIGGGYLLFGAMLYGSFFMHRGVPYFPNLVMPIVVGGIGIGMAVVPLT  420
            SQLVSRFSPRVLTIGGGYLLFGAMLYGSFFMHRGVPYFPNLVMPIVVGGIGIGMAVVPLT
Sbjct  360  SQLVSRFSPRVLTIGGGYLLFGAMLYGSFFMHRGVPYFPNLVMPIVVGGIGIGMAVVPLT  419

Query  421  LSAIAGVGFDQIGPVSAIALMLQSLGGPLVLAVIQAVITSRTLYLGGTTGPVKFMNDVQL  480
            LSAIAGVGFDQIGPVSAIALMLQSLGGPLVLAVIQAVITSRTLYLGGTTGPVKFMNDVQL
Sbjct  420  LSAIAGVGFDQIGPVSAIALMLQSLGGPLVLAVIQAVITSRTLYLGGTTGPVKFMNDVQL  479

Query  481  AALDHAYTYGLLWVAGAAIIVGGMALFIGYTPQQVAHAQEVKEAIDAGEL  530
            AALDHAYTYGLLWVAGAAIIVGGMALFIGYTPQQVAHAQEVKEAIDAGEL
Sbjct  480  AALDHAYTYGLLWVAGAAIIVGGMALFIGYTPQQVAHAQEVKEAIDAGEL  529


>gi|339295687|gb|AEJ47798.1| integral membrane efflux protein EfpA [Mycobacterium tuberculosis 
CCDC5079]
 gi|339299302|gb|AEJ51412.1| integral membrane efflux protein EfpA [Mycobacterium tuberculosis 
CCDC5180]
Length=470

 Score =  917 bits (2370),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 470/470 (100%), Positives = 470/470 (100%), Gaps = 0/470 (0%)

Query  61   MQLLATMDSTVAIVALPKIQNELSLSDAGRSWVITAYVLTFGGLMLLGGRLGDTIGRKRT  120
            MQLLATMDSTVAIVALPKIQNELSLSDAGRSWVITAYVLTFGGLMLLGGRLGDTIGRKRT
Sbjct  1    MQLLATMDSTVAIVALPKIQNELSLSDAGRSWVITAYVLTFGGLMLLGGRLGDTIGRKRT  60

Query  121  FIVGVALFTISSVLCAVAWDEATLVIARLSQGVGSAIASPTGLALVATTFPKGPARNAAT  180
            FIVGVALFTISSVLCAVAWDEATLVIARLSQGVGSAIASPTGLALVATTFPKGPARNAAT
Sbjct  61   FIVGVALFTISSVLCAVAWDEATLVIARLSQGVGSAIASPTGLALVATTFPKGPARNAAT  120

Query  181  AVFAAMTAIGSVMGLVVGGALTEVSWRWAFLVNVPIGLVMIYLARTALRETNKERMKLDA  240
            AVFAAMTAIGSVMGLVVGGALTEVSWRWAFLVNVPIGLVMIYLARTALRETNKERMKLDA
Sbjct  121  AVFAAMTAIGSVMGLVVGGALTEVSWRWAFLVNVPIGLVMIYLARTALRETNKERMKLDA  180

Query  241  TGAILATLACTAAVFAFSIGPEKGWMSGITIGSGLVALAAAVAFVIVERTAENPVVPFHL  300
            TGAILATLACTAAVFAFSIGPEKGWMSGITIGSGLVALAAAVAFVIVERTAENPVVPFHL
Sbjct  181  TGAILATLACTAAVFAFSIGPEKGWMSGITIGSGLVALAAAVAFVIVERTAENPVVPFHL  240

Query  301  FRDRNRLVTFSAILLAGGVMFSLTVCIGLYVQDILGYSALRAGVGFIPFVIAMGIGLGVS  360
            FRDRNRLVTFSAILLAGGVMFSLTVCIGLYVQDILGYSALRAGVGFIPFVIAMGIGLGVS
Sbjct  241  FRDRNRLVTFSAILLAGGVMFSLTVCIGLYVQDILGYSALRAGVGFIPFVIAMGIGLGVS  300

Query  361  SQLVSRFSPRVLTIGGGYLLFGAMLYGSFFMHRGVPYFPNLVMPIVVGGIGIGMAVVPLT  420
            SQLVSRFSPRVLTIGGGYLLFGAMLYGSFFMHRGVPYFPNLVMPIVVGGIGIGMAVVPLT
Sbjct  301  SQLVSRFSPRVLTIGGGYLLFGAMLYGSFFMHRGVPYFPNLVMPIVVGGIGIGMAVVPLT  360

Query  421  LSAIAGVGFDQIGPVSAIALMLQSLGGPLVLAVIQAVITSRTLYLGGTTGPVKFMNDVQL  480
            LSAIAGVGFDQIGPVSAIALMLQSLGGPLVLAVIQAVITSRTLYLGGTTGPVKFMNDVQL
Sbjct  361  LSAIAGVGFDQIGPVSAIALMLQSLGGPLVLAVIQAVITSRTLYLGGTTGPVKFMNDVQL  420

Query  481  AALDHAYTYGLLWVAGAAIIVGGMALFIGYTPQQVAHAQEVKEAIDAGEL  530
            AALDHAYTYGLLWVAGAAIIVGGMALFIGYTPQQVAHAQEVKEAIDAGEL
Sbjct  421  AALDHAYTYGLLWVAGAAIIVGGMALFIGYTPQQVAHAQEVKEAIDAGEL  470


>gi|183981900|ref|YP_001850191.1| integral membrane efflux protein EfpA [Mycobacterium marinum 
M]
 gi|183175226|gb|ACC40336.1| integral membrane efflux protein EfpA [Mycobacterium marinum 
M]
Length=530

 Score =  890 bits (2300),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 478/530 (91%), Positives = 496/530 (94%), Gaps = 0/530 (0%)

Query  1    MTALNDTERAVRNWTAGRPHRPAPMRPPRSEETASERPSRYYPTWLPSRSFIAAVIAIGG  60
            MTALNDTERAV NWT+GR  RP   R  R  ETASER SRYYPTWLPSR FIAAVIAIGG
Sbjct  1    MTALNDTERAVHNWTSGRQERPTSARATRETETASERASRYYPTWLPSRRFIAAVIAIGG  60

Query  61   MQLLATMDSTVAIVALPKIQNELSLSDAGRSWVITAYVLTFGGLMLLGGRLGDTIGRKRT  120
            MQLLATMDSTVAIVALPKIQ+ELSLSDAGRSWVITAYVLTFGGLMLLGGRLGDTIGRKRT
Sbjct  61   MQLLATMDSTVAIVALPKIQDELSLSDAGRSWVITAYVLTFGGLMLLGGRLGDTIGRKRT  120

Query  121  FIVGVALFTISSVLCAVAWDEATLVIARLSQGVGSAIASPTGLALVATTFPKGPARNAAT  180
            FIVGVALFTISSVLCAVAWDEATLVIARLSQGVGSAIASPTGLALVATTFPKGPARNAAT
Sbjct  121  FIVGVALFTISSVLCAVAWDEATLVIARLSQGVGSAIASPTGLALVATTFPKGPARNAAT  180

Query  181  AVFAAMTAIGSVMGLVVGGALTEVSWRWAFLVNVPIGLVMIYLARTALRETNKERMKLDA  240
            AVFAAMTA+GSVMGLVVGGALTEVSWR AF+VNVPIGLVMIYLARTALRETN+ERMKLDA
Sbjct  181  AVFAAMTAVGSVMGLVVGGALTEVSWRLAFMVNVPIGLVMIYLARTALRETNRERMKLDA  240

Query  241  TGAILATLACTAAVFAFSIGPEKGWMSGITIGSGLVALAAAVAFVIVERTAENPVVPFHL  300
             GAILATLACTAAVFAFS+GPEKGW+S  TIGSG VA AAA+ FV+VERTAENPVVPF L
Sbjct  241  AGAILATLACTAAVFAFSMGPEKGWLSITTIGSGAVAFAAALGFVLVERTAENPVVPFDL  300

Query  301  FRDRNRLVTFSAILLAGGVMFSLTVCIGLYVQDILGYSALRAGVGFIPFVIAMGIGLGVS  360
            F DRNRLVTF AI LAGGVMFSLTVCIGLYVQD+LGYSALRAGVGFIPFVIAMGIGLGVS
Sbjct  301  FHDRNRLVTFIAIFLAGGVMFSLTVCIGLYVQDVLGYSALRAGVGFIPFVIAMGIGLGVS  360

Query  361  SQLVSRFSPRVLTIGGGYLLFGAMLYGSFFMHRGVPYFPNLVMPIVVGGIGIGMAVVPLT  420
            SQLVSRFSPRVLTIGGGYLL  AM+YG  FM RGVPYFPNLV PIV+GGIGIGMAVVPLT
Sbjct  361  SQLVSRFSPRVLTIGGGYLLVCAMIYGWAFMQRGVPYFPNLVAPIVIGGIGIGMAVVPLT  420

Query  421  LSAIAGVGFDQIGPVSAIALMLQSLGGPLVLAVIQAVITSRTLYLGGTTGPVKFMNDVQL  480
            L+AIAGVGFD+IGPVSA+ LMLQSLGGPLVLAVIQAVITSRTLYLGGTTGPVKFMND QL
Sbjct  421  LAAIAGVGFDRIGPVSALTLMLQSLGGPLVLAVIQAVITSRTLYLGGTTGPVKFMNDAQL  480

Query  481  AALDHAYTYGLLWVAGAAIIVGGMALFIGYTPQQVAHAQEVKEAIDAGEL  530
             ALDH YTYGLLWVAGAA+IVGG A+FIGYTP+QVAHAQEVKEAIDAGEL
Sbjct  481  HALDHGYTYGLLWVAGAAVIVGGAAVFIGYTPEQVAHAQEVKEAIDAGEL  530


>gi|118617675|ref|YP_906007.1| integral membrane efflux protein EfpA [Mycobacterium ulcerans 
Agy99]
 gi|118569785|gb|ABL04536.1| integral membrane efflux protein EfpA [Mycobacterium ulcerans 
Agy99]
Length=530

 Score =  885 bits (2288),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 476/530 (90%), Positives = 494/530 (94%), Gaps = 0/530 (0%)

Query  1    MTALNDTERAVRNWTAGRPHRPAPMRPPRSEETASERPSRYYPTWLPSRSFIAAVIAIGG  60
            MTALNDTERAV NWT+GR  RP   R  R  ETASER SRYYPTWLPSR FIAAVIAIGG
Sbjct  1    MTALNDTERAVHNWTSGRQERPTSARATRETETASERASRYYPTWLPSRRFIAAVIAIGG  60

Query  61   MQLLATMDSTVAIVALPKIQNELSLSDAGRSWVITAYVLTFGGLMLLGGRLGDTIGRKRT  120
            MQLLATMDSTVAIVALPKIQ+ELSLSDAGRSWVITAYVLTFGGLMLLGGRLGDTIGRKRT
Sbjct  61   MQLLATMDSTVAIVALPKIQDELSLSDAGRSWVITAYVLTFGGLMLLGGRLGDTIGRKRT  120

Query  121  FIVGVALFTISSVLCAVAWDEATLVIARLSQGVGSAIASPTGLALVATTFPKGPARNAAT  180
            FIVGVALFTISSVLCAVAWDEATLVIARLSQGVGSAIASPTGLALVATTFPKGP RNAAT
Sbjct  121  FIVGVALFTISSVLCAVAWDEATLVIARLSQGVGSAIASPTGLALVATTFPKGPTRNAAT  180

Query  181  AVFAAMTAIGSVMGLVVGGALTEVSWRWAFLVNVPIGLVMIYLARTALRETNKERMKLDA  240
            AVFAAMTA+GSVMGLVVGGALTEVSWR AF+VNVPIGLVMIYLARTALRETN+ERMKLDA
Sbjct  181  AVFAAMTAVGSVMGLVVGGALTEVSWRLAFMVNVPIGLVMIYLARTALRETNRERMKLDA  240

Query  241  TGAILATLACTAAVFAFSIGPEKGWMSGITIGSGLVALAAAVAFVIVERTAENPVVPFHL  300
             GAILATLACTAAVFAFS+GPEKGW+S  TIGSG VA AAA+ FV+VERTAENPVVPF L
Sbjct  241  AGAILATLACTAAVFAFSMGPEKGWLSITTIGSGAVAFAAALGFVLVERTAENPVVPFDL  300

Query  301  FRDRNRLVTFSAILLAGGVMFSLTVCIGLYVQDILGYSALRAGVGFIPFVIAMGIGLGVS  360
            F DRNRLVTF AI LAGGVMFSLTVCIGLYVQD+LGYSALRAGVGFIPFVIAMGIGLGVS
Sbjct  301  FHDRNRLVTFIAIFLAGGVMFSLTVCIGLYVQDVLGYSALRAGVGFIPFVIAMGIGLGVS  360

Query  361  SQLVSRFSPRVLTIGGGYLLFGAMLYGSFFMHRGVPYFPNLVMPIVVGGIGIGMAVVPLT  420
            SQLVSRFSPRVLTIGGGYLL  AM+YG  FM RGVPYFPNLV PIV+GGIGIGMAVVPLT
Sbjct  361  SQLVSRFSPRVLTIGGGYLLVCAMIYGWAFMQRGVPYFPNLVAPIVIGGIGIGMAVVPLT  420

Query  421  LSAIAGVGFDQIGPVSAIALMLQSLGGPLVLAVIQAVITSRTLYLGGTTGPVKFMNDVQL  480
            L+AIAGVGFD+IGPVSA+ LMLQSLGGPLVLA IQAVITSRTLYLGGTTGPVKFMND QL
Sbjct  421  LAAIAGVGFDRIGPVSALTLMLQSLGGPLVLAGIQAVITSRTLYLGGTTGPVKFMNDAQL  480

Query  481  AALDHAYTYGLLWVAGAAIIVGGMALFIGYTPQQVAHAQEVKEAIDAGEL  530
             ALDH YTYGLLWVAGAA+IVGG A+FIGYTP+QVAHAQEVKEAIDAGEL
Sbjct  481  HALDHGYTYGLLWVAGAAVIVGGAAVFIGYTPEQVAHAQEVKEAIDAGEL  530


>gi|342858322|ref|ZP_08714977.1| transporter, major facilitator family protein [Mycobacterium 
colombiense CECT 3035]
 gi|342134026|gb|EGT87206.1| transporter, major facilitator family protein [Mycobacterium 
colombiense CECT 3035]
Length=538

 Score =  885 bits (2286),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 470/540 (88%), Positives = 497/540 (93%), Gaps = 12/540 (2%)

Query  1    MTALNDTERAVRNWTAGRPHRPAPM----------RPPRSEETASERPSRYYPTWLPSRS  50
            MTALND ERAV+N  + RP RPAP+          +PP   ETA +R S+YYP WLPSR 
Sbjct  1    MTALNDAERAVQNQASARPDRPAPVSSAFPAETASKPP--AETALKRISKYYPAWLPSRR  58

Query  51   FIAAVIAIGGMQLLATMDSTVAIVALPKIQNELSLSDAGRSWVITAYVLTFGGLMLLGGR  110
            FIAAVIAIGGMQLLATMDSTVAIVALPKIQNELSLSDAGRSWVITAYVLTFGGLMLLGGR
Sbjct  59   FIAAVIAIGGMQLLATMDSTVAIVALPKIQNELSLSDAGRSWVITAYVLTFGGLMLLGGR  118

Query  111  LGDTIGRKRTFIVGVALFTISSVLCAVAWDEATLVIARLSQGVGSAIASPTGLALVATTF  170
            LGDTIGRKRTFIVGVALFTISSVLCAVAWDEAT+VIARLSQGVGSAIASPTGLALVATTF
Sbjct  119  LGDTIGRKRTFIVGVALFTISSVLCAVAWDEATMVIARLSQGVGSAIASPTGLALVATTF  178

Query  171  PKGPARNAATAVFAAMTAIGSVMGLVVGGALTEVSWRWAFLVNVPIGLVMIYLARTALRE  230
            PKGPARN ATAVFAAMTA+GSVMGLVVGGALTEVSWR AFLVNVPIGLVM+YLARTALRE
Sbjct  179  PKGPARNFATAVFAAMTAVGSVMGLVVGGALTEVSWRLAFLVNVPIGLVMMYLARTALRE  238

Query  231  TNKERMKLDATGAILATLACTAAVFAFSIGPEKGWMSGITIGSGLVALAAAVAFVIVERT  290
            TN+ERMKLDATGA+LATLACTAAVFAFS+GPEKGW+S  TIGSG+VAL A +AF+IVERT
Sbjct  239  TNRERMKLDATGALLATLACTAAVFAFSMGPEKGWVSITTIGSGVVALGAGLAFIIVERT  298

Query  291  AENPVVPFHLFRDRNRLVTFSAILLAGGVMFSLTVCIGLYVQDILGYSALRAGVGFIPFV  350
            AENPVVPF LFRDRNRLVTF+AI LAGG+MFSLTVCIGLYVQDILGYSALRAGVGFIPFV
Sbjct  299  AENPVVPFDLFRDRNRLVTFTAIFLAGGLMFSLTVCIGLYVQDILGYSALRAGVGFIPFV  358

Query  351  IAMGIGLGVSSQLVSRFSPRVLTIGGGYLLFGAMLYGSFFMHRGVPYFPNLVMPIVVGGI  410
            IAMGIGLGVSSQLVSRFSPRVLTIGGG +LF AML+G  FMHRG  YFPNLV+PIVVGGI
Sbjct  359  IAMGIGLGVSSQLVSRFSPRVLTIGGGIMLFWAMLFGWAFMHRGAAYFPNLVLPIVVGGI  418

Query  411  GIGMAVVPLTLSAIAGVGFDQIGPVSAIALMLQSLGGPLVLAVIQAVITSRTLYLGGTTG  470
            GIGMAVVPLTLSAIAGVGFDQIGPVSA+ LMLQSLGGPLVLAVIQAVITSRTLY+GGTTG
Sbjct  419  GIGMAVVPLTLSAIAGVGFDQIGPVSAVTLMLQSLGGPLVLAVIQAVITSRTLYMGGTTG  478

Query  471  PVKFMNDVQLAALDHAYTYGLLWVAGAAIIVGGMALFIGYTPQQVAHAQEVKEAIDAGEL  530
            PVKFMND QLAALD+ YTYGLLW+AG A+IVGG AL IGYTP QVAHAQEVKEA+DAGEL
Sbjct  479  PVKFMNDAQLAALDNGYTYGLLWLAGVAVIVGGAALLIGYTPDQVAHAQEVKEAMDAGEL  538


>gi|41409013|ref|NP_961849.1| EfpA_2 [Mycobacterium avium subsp. paratuberculosis K-10]
 gi|118463672|ref|YP_882879.1| transporter, major facilitator family protein [Mycobacterium 
avium 104]
 gi|41397372|gb|AAS05232.1| EfpA_2 [Mycobacterium avium subsp. paratuberculosis K-10]
 gi|118164959|gb|ABK65856.1| transporter, major facilitator family protein [Mycobacterium 
avium 104]
 gi|336458989|gb|EGO37941.1| arabinose efflux permease family protein [Mycobacterium avium 
subsp. paratuberculosis S397]
Length=538

 Score =  880 bits (2274),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 475/538 (89%), Positives = 500/538 (93%), Gaps = 8/538 (1%)

Query  1    MTALNDTERAVRNWTAGRPHRPAPMR--------PPRSEETASERPSRYYPTWLPSRSFI  52
            MTALND+ERAV+NWT+ RP RPAP+R        P  + ETA +R S+YYP WLPSR FI
Sbjct  1    MTALNDSERAVQNWTSARPDRPAPVRSTPPAETAPKPAAETAVKRTSKYYPAWLPSRRFI  60

Query  53   AAVIAIGGMQLLATMDSTVAIVALPKIQNELSLSDAGRSWVITAYVLTFGGLMLLGGRLG  112
            AAVIAIGGMQLLATMDSTVAIVALP+IQNELSLSDAGRSWVITAYVLTFGGLMLLGGRLG
Sbjct  61   AAVIAIGGMQLLATMDSTVAIVALPRIQNELSLSDAGRSWVITAYVLTFGGLMLLGGRLG  120

Query  113  DTIGRKRTFIVGVALFTISSVLCAVAWDEATLVIARLSQGVGSAIASPTGLALVATTFPK  172
            DTIGRKRTFIVGVALFTISSVLCAVAWDEAT+VIARLSQGVGSAIASPTGLALVATTFPK
Sbjct  121  DTIGRKRTFIVGVALFTISSVLCAVAWDEATMVIARLSQGVGSAIASPTGLALVATTFPK  180

Query  173  GPARNAATAVFAAMTAIGSVMGLVVGGALTEVSWRWAFLVNVPIGLVMIYLARTALRETN  232
            GPARN ATAVFAAMTA+GSVMGLVVGGALTEVSWR AFLVNVPIGLVM+YLARTALRETN
Sbjct  181  GPARNFATAVFAAMTAVGSVMGLVVGGALTEVSWRLAFLVNVPIGLVMMYLARTALRETN  240

Query  233  KERMKLDATGAILATLACTAAVFAFSIGPEKGWMSGITIGSGLVALAAAVAFVIVERTAE  292
            +ERMKLDATGA+LATLACTAAVFAFS+GPEKGW+S  TI SG+VAL AA+AFVIVERTAE
Sbjct  241  RERMKLDATGAVLATLACTAAVFAFSMGPEKGWISLTTISSGVVALGAALAFVIVERTAE  300

Query  293  NPVVPFHLFRDRNRLVTFSAILLAGGVMFSLTVCIGLYVQDILGYSALRAGVGFIPFVIA  352
            NPVVPF LFRDRNRLVTF AI LAGGVMF+LTVCIGLYVQDILGYSALRAGVGFIPFVIA
Sbjct  301  NPVVPFDLFRDRNRLVTFIAIFLAGGVMFTLTVCIGLYVQDILGYSALRAGVGFIPFVIA  360

Query  353  MGIGLGVSSQLVSRFSPRVLTIGGGYLLFGAMLYGSFFMHRGVPYFPNLVMPIVVGGIGI  412
            MGIGLGVSSQLV+RFSPRVLTI GGYLL  AMLYG + MHRGVPYFPNLV+PIVVGGIGI
Sbjct  361  MGIGLGVSSQLVARFSPRVLTIAGGYLLVLAMLYGWWCMHRGVPYFPNLVLPIVVGGIGI  420

Query  413  GMAVVPLTLSAIAGVGFDQIGPVSAIALMLQSLGGPLVLAVIQAVITSRTLYLGGTTGPV  472
            GMAVVPLTLSAIAGVGFDQIGPVSA+ LMLQSLGGPLVLAVIQAVITSRTLYLGGTTGPV
Sbjct  421  GMAVVPLTLSAIAGVGFDQIGPVSAVTLMLQSLGGPLVLAVIQAVITSRTLYLGGTTGPV  480

Query  473  KFMNDVQLAALDHAYTYGLLWVAGAAIIVGGMALFIGYTPQQVAHAQEVKEAIDAGEL  530
            K MND QL ALDH YTYGLLWVAGAA+IVG  ALFIGYTP+QVAHAQEVKEA+DAGEL
Sbjct  481  KTMNDAQLQALDHGYTYGLLWVAGAAVIVGAAALFIGYTPEQVAHAQEVKEAMDAGEL  538


>gi|240172753|ref|ZP_04751412.1| integral membrane efflux protein EfpA [Mycobacterium kansasii 
ATCC 12478]
Length=530

 Score =  872 bits (2254),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 480/530 (91%), Positives = 499/530 (95%), Gaps = 0/530 (0%)

Query  1    MTALNDTERAVRNWTAGRPHRPAPMRPPRSEETASERPSRYYPTWLPSRSFIAAVIAIGG  60
            MTALNDTERA  NWT+GR  RPA  RP RS ETAS+R +RYYPTWLPSR FIAAVIAIGG
Sbjct  1    MTALNDTERAAHNWTSGRQERPASARPARSAETASQRITRYYPTWLPSRRFIAAVIAIGG  60

Query  61   MQLLATMDSTVAIVALPKIQNELSLSDAGRSWVITAYVLTFGGLMLLGGRLGDTIGRKRT  120
            MQLLATMDSTVAIVALPKIQNELSLSDAGRSWVITAYVLTFGGLMLLGGRLGDTIGRKRT
Sbjct  61   MQLLATMDSTVAIVALPKIQNELSLSDAGRSWVITAYVLTFGGLMLLGGRLGDTIGRKRT  120

Query  121  FIVGVALFTISSVLCAVAWDEATLVIARLSQGVGSAIASPTGLALVATTFPKGPARNAAT  180
            FIVGVALFTISSVLCAVAWDEAT+VIARLSQGVGSAIASPTGLALVATTFPKGPARNAAT
Sbjct  121  FIVGVALFTISSVLCAVAWDEATMVIARLSQGVGSAIASPTGLALVATTFPKGPARNAAT  180

Query  181  AVFAAMTAIGSVMGLVVGGALTEVSWRWAFLVNVPIGLVMIYLARTALRETNKERMKLDA  240
            AVFAAMTAIGSVMGLVVGGALTEVSWR AFLVNVPIGLVMIYLARTALRETN+ERMKLDA
Sbjct  181  AVFAAMTAIGSVMGLVVGGALTEVSWRLAFLVNVPIGLVMIYLARTALRETNRERMKLDA  240

Query  241  TGAILATLACTAAVFAFSIGPEKGWMSGITIGSGLVALAAAVAFVIVERTAENPVVPFHL  300
             GA+LATLACTAAVFAFS+GPEKGW+S  TIGSG VALAA +AF++VERTAENPVVPFHL
Sbjct  241  AGAMLATLACTAAVFAFSMGPEKGWISVTTIGSGAVALAAVLAFIVVERTAENPVVPFHL  300

Query  301  FRDRNRLVTFSAILLAGGVMFSLTVCIGLYVQDILGYSALRAGVGFIPFVIAMGIGLGVS  360
            FRDRNRLVTF AI LAGGVMF+LTV IGLYVQDILGYSALRAGVGFIPFVIAMGIGLG+S
Sbjct  301  FRDRNRLVTFIAIFLAGGVMFTLTVSIGLYVQDILGYSALRAGVGFIPFVIAMGIGLGIS  360

Query  361  SQLVSRFSPRVLTIGGGYLLFGAMLYGSFFMHRGVPYFPNLVMPIVVGGIGIGMAVVPLT  420
            SQLVSRFSPRVLTI GGYLL  AMLYG  FMHRGV YFPNLV+PIVVGG+GIGMAVVPLT
Sbjct  361  SQLVSRFSPRVLTIAGGYLLVLAMLYGWLFMHRGVAYFPNLVVPIVVGGVGIGMAVVPLT  420

Query  421  LSAIAGVGFDQIGPVSAIALMLQSLGGPLVLAVIQAVITSRTLYLGGTTGPVKFMNDVQL  480
            LSAIAGVGFDQIGPVSA+ LMLQSLGGPLVLAVIQAVITSRTLYLGGTTGPVKFMND QL
Sbjct  421  LSAIAGVGFDQIGPVSAMTLMLQSLGGPLVLAVIQAVITSRTLYLGGTTGPVKFMNDAQL  480

Query  481  AALDHAYTYGLLWVAGAAIIVGGMALFIGYTPQQVAHAQEVKEAIDAGEL  530
            AALDH YTYGLLW+AGAA+IVGG A+ IGYTP QVAHAQEVKEAIDAGEL
Sbjct  481  AALDHGYTYGLLWIAGAAVIVGGAAVLIGYTPAQVAHAQEVKEAIDAGEL  530


>gi|296171595|ref|ZP_06852835.1| efflux protein [Mycobacterium parascrofulaceum ATCC BAA-614]
 gi|295894050|gb|EFG73812.1| efflux protein [Mycobacterium parascrofulaceum ATCC BAA-614]
Length=530

 Score =  870 bits (2249),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 480/530 (91%), Positives = 501/530 (95%), Gaps = 0/530 (0%)

Query  1    MTALNDTERAVRNWTAGRPHRPAPMRPPRSEETASERPSRYYPTWLPSRSFIAAVIAIGG  60
            MTALND+ERAVRN+T+ RP RPAP+R  R  ETAS R S+YYP WLPSR FIAAVIAIGG
Sbjct  1    MTALNDSERAVRNFTSARPDRPAPVRATRPAETASTRISKYYPAWLPSRRFIAAVIAIGG  60

Query  61   MQLLATMDSTVAIVALPKIQNELSLSDAGRSWVITAYVLTFGGLMLLGGRLGDTIGRKRT  120
            MQLLATMDSTVAIVALP+IQNELSLSDAGRSWVITAYVLTFGGLMLLGGRLGDTIGRKRT
Sbjct  61   MQLLATMDSTVAIVALPRIQNELSLSDAGRSWVITAYVLTFGGLMLLGGRLGDTIGRKRT  120

Query  121  FIVGVALFTISSVLCAVAWDEATLVIARLSQGVGSAIASPTGLALVATTFPKGPARNAAT  180
            FIVGVALFTISSVLCAVAWDEAT+VIARLSQGVGSAIASPTGLALVATTFPKGPARN AT
Sbjct  121  FIVGVALFTISSVLCAVAWDEATMVIARLSQGVGSAIASPTGLALVATTFPKGPARNFAT  180

Query  181  AVFAAMTAIGSVMGLVVGGALTEVSWRWAFLVNVPIGLVMIYLARTALRETNKERMKLDA  240
            AVFAAMTAIGSVMGLVVGGALTEVSWR AFLVNVPIGLVMIYLARTALRETN+ERMKLDA
Sbjct  181  AVFAAMTAIGSVMGLVVGGALTEVSWRLAFLVNVPIGLVMIYLARTALRETNRERMKLDA  240

Query  241  TGAILATLACTAAVFAFSIGPEKGWMSGITIGSGLVALAAAVAFVIVERTAENPVVPFHL  300
            TGA+LATLACTAAVFAFS+GPEKGW+S  TIGSG+VALAAA+AF+IVERTAENPVVPF L
Sbjct  241  TGAMLATLACTAAVFAFSMGPEKGWVSITTIGSGVVALAAALAFIIVERTAENPVVPFSL  300

Query  301  FRDRNRLVTFSAILLAGGVMFSLTVCIGLYVQDILGYSALRAGVGFIPFVIAMGIGLGVS  360
            FRDRNRLVTF+AI LAGG+MFSLTVCIGLYVQDILGYSALRAGVGFIPFVIAMGIGLGVS
Sbjct  301  FRDRNRLVTFAAIFLAGGLMFSLTVCIGLYVQDILGYSALRAGVGFIPFVIAMGIGLGVS  360

Query  361  SQLVSRFSPRVLTIGGGYLLFGAMLYGSFFMHRGVPYFPNLVMPIVVGGIGIGMAVVPLT  420
            SQLVSRFSPRVLTIGGG LLF AMLYG  FMHRGVPYFPNLV+PI+VGGIGIG+ VVPLT
Sbjct  361  SQLVSRFSPRVLTIGGGILLFWAMLYGWGFMHRGVPYFPNLVLPIIVGGIGIGICVVPLT  420

Query  421  LSAIAGVGFDQIGPVSAIALMLQSLGGPLVLAVIQAVITSRTLYLGGTTGPVKFMNDVQL  480
            LSAIAGVGFDQIGPVSAIALMLQSLGGPLVLAVIQAVITSRTLYLGGTTGPVK MND+QL
Sbjct  421  LSAIAGVGFDQIGPVSAIALMLQSLGGPLVLAVIQAVITSRTLYLGGTTGPVKIMNDLQL  480

Query  481  AALDHAYTYGLLWVAGAAIIVGGMALFIGYTPQQVAHAQEVKEAIDAGEL  530
             ALD  YTYGLLWVAG A+IVGG AL IGYTP QVAHAQEVKEAIDAGEL
Sbjct  481  HALDQGYTYGLLWVAGVAVIVGGAALLIGYTPAQVAHAQEVKEAIDAGEL  530


>gi|289444397|ref|ZP_06434141.1| membrane efflux protein efpA [Mycobacterium tuberculosis T46]
 gi|289417316|gb|EFD14556.1| membrane efflux protein efpA [Mycobacterium tuberculosis T46]
Length=446

 Score =  869 bits (2246),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 445/446 (99%), Positives = 446/446 (100%), Gaps = 0/446 (0%)

Query  85   LSDAGRSWVITAYVLTFGGLMLLGGRLGDTIGRKRTFIVGVALFTISSVLCAVAWDEATL  144
            +SDAGRSWVITAYVLTFGGLMLLGGRLGDTIGRKRTFIVGVALFTISSVLCAVAWDEATL
Sbjct  1    MSDAGRSWVITAYVLTFGGLMLLGGRLGDTIGRKRTFIVGVALFTISSVLCAVAWDEATL  60

Query  145  VIARLSQGVGSAIASPTGLALVATTFPKGPARNAATAVFAAMTAIGSVMGLVVGGALTEV  204
            VIARLSQGVGSAIASPTGLALVATTFPKGPARNAATAVFAAMTAIGSVMGLVVGGALTEV
Sbjct  61   VIARLSQGVGSAIASPTGLALVATTFPKGPARNAATAVFAAMTAIGSVMGLVVGGALTEV  120

Query  205  SWRWAFLVNVPIGLVMIYLARTALRETNKERMKLDATGAILATLACTAAVFAFSIGPEKG  264
            SWRWAFLVNVPIGLVMIYLARTALRETNKERMKLDATGAILATLACTAAVFAFSIGPEKG
Sbjct  121  SWRWAFLVNVPIGLVMIYLARTALRETNKERMKLDATGAILATLACTAAVFAFSIGPEKG  180

Query  265  WMSGITIGSGLVALAAAVAFVIVERTAENPVVPFHLFRDRNRLVTFSAILLAGGVMFSLT  324
            WMSGITIGSGLVALAAAVAFVIVERTAENPVVPFHLFRDRNRLVTFSAILLAGGVMFSLT
Sbjct  181  WMSGITIGSGLVALAAAVAFVIVERTAENPVVPFHLFRDRNRLVTFSAILLAGGVMFSLT  240

Query  325  VCIGLYVQDILGYSALRAGVGFIPFVIAMGIGLGVSSQLVSRFSPRVLTIGGGYLLFGAM  384
            VCIGLYVQDILGYSALRAGVGFIPFVIAMGIGLGVSSQLVSRFSPRVLTIGGGYLLFGAM
Sbjct  241  VCIGLYVQDILGYSALRAGVGFIPFVIAMGIGLGVSSQLVSRFSPRVLTIGGGYLLFGAM  300

Query  385  LYGSFFMHRGVPYFPNLVMPIVVGGIGIGMAVVPLTLSAIAGVGFDQIGPVSAIALMLQS  444
            LYGSFFMHRGVPYFPNLVMPIVVGGIGIGMAVVPLTLSAIAGVGFDQIGPVSAIALMLQS
Sbjct  301  LYGSFFMHRGVPYFPNLVMPIVVGGIGIGMAVVPLTLSAIAGVGFDQIGPVSAIALMLQS  360

Query  445  LGGPLVLAVIQAVITSRTLYLGGTTGPVKFMNDVQLAALDHAYTYGLLWVAGAAIIVGGM  504
            LGGPLVLAVIQAVITSRTLYLGGTTGPVKFMNDVQLAALDHAYTYGLLWVAGAAIIVGGM
Sbjct  361  LGGPLVLAVIQAVITSRTLYLGGTTGPVKFMNDVQLAALDHAYTYGLLWVAGAAIIVGGM  420

Query  505  ALFIGYTPQQVAHAQEVKEAIDAGEL  530
            ALFIGYTPQQVAHAQEVKEAIDAGEL
Sbjct  421  ALFIGYTPQQVAHAQEVKEAIDAGEL  446


>gi|254819681|ref|ZP_05224682.1| transporter, major facilitator family protein [Mycobacterium 
intracellulare ATCC 13950]
Length=511

 Score =  852 bits (2201),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 452/505 (90%), Positives = 472/505 (94%), Gaps = 2/505 (0%)

Query  26   RPPRSEETASERPSRYYPTWLPSRSFIAAVIAIGGMQLLATMDSTVAIVALPKIQNELSL  85
            +PP   ETAS R S+YYP WLPSR FIAAVIAIGGMQLLATMDSTVAIVALPKIQNELSL
Sbjct  9    KPP--AETASNRISKYYPAWLPSRRFIAAVIAIGGMQLLATMDSTVAIVALPKIQNELSL  66

Query  86   SDAGRSWVITAYVLTFGGLMLLGGRLGDTIGRKRTFIVGVALFTISSVLCAVAWDEATLV  145
            SDAGRSWVITAYVLTFGGLMLLGGRLGDTIGRKRTFIVGVALFTISSVLCAVAWDEAT+V
Sbjct  67   SDAGRSWVITAYVLTFGGLMLLGGRLGDTIGRKRTFIVGVALFTISSVLCAVAWDEATMV  126

Query  146  IARLSQGVGSAIASPTGLALVATTFPKGPARNAATAVFAAMTAIGSVMGLVVGGALTEVS  205
            IARLSQGVGSAIASPTGLALVATTFPKGPARN ATAVFAAMTA+GSVMGLVVGGALTEVS
Sbjct  127  IARLSQGVGSAIASPTGLALVATTFPKGPARNFATAVFAAMTAVGSVMGLVVGGALTEVS  186

Query  206  WRWAFLVNVPIGLVMIYLARTALRETNKERMKLDATGAILATLACTAAVFAFSIGPEKGW  265
            WR AFLVNVPIGLVM+YLARTALRETN+ERMKLDATGA+LATL CTAAVFAFS+GPEKGW
Sbjct  187  WRLAFLVNVPIGLVMMYLARTALRETNRERMKLDATGAMLATLTCTAAVFAFSMGPEKGW  246

Query  266  MSGITIGSGLVALAAAVAFVIVERTAENPVVPFHLFRDRNRLVTFSAILLAGGVMFSLTV  325
            +S  TIGSG+VA+ A + F+IVERTAENPVVPF LFRDRNRLVTF+AI LAGG+MFSLTV
Sbjct  247  VSITTIGSGVVAMLAGLGFIIVERTAENPVVPFDLFRDRNRLVTFTAIFLAGGLMFSLTV  306

Query  326  CIGLYVQDILGYSALRAGVGFIPFVIAMGIGLGVSSQLVSRFSPRVLTIGGGYLLFGAML  385
            CIGLYVQDILGYSAL AGVGFIPFVIAMGIGLG+SSQLVSRFSPRVLTIGGG LLF AML
Sbjct  307  CIGLYVQDILGYSALHAGVGFIPFVIAMGIGLGISSQLVSRFSPRVLTIGGGILLFWAML  366

Query  386  YGSFFMHRGVPYFPNLVMPIVVGGIGIGMAVVPLTLSAIAGVGFDQIGPVSAIALMLQSL  445
            YG  FMHRGV YFPNLV+PIVVGGIGIGMAVVPLTLSAIAGVGFDQIGPVSA+ LMLQSL
Sbjct  367  YGWAFMHRGVAYFPNLVLPIVVGGIGIGMAVVPLTLSAIAGVGFDQIGPVSAVTLMLQSL  426

Query  446  GGPLVLAVIQAVITSRTLYLGGTTGPVKFMNDVQLAALDHAYTYGLLWVAGAAIIVGGMA  505
            GGPLVLAVIQAVITSRTLYLGGTTGPVK M D QL ALDH YTYGLLWVAG A+IVGG A
Sbjct  427  GGPLVLAVIQAVITSRTLYLGGTTGPVKNMTDAQLQALDHGYTYGLLWVAGVAVIVGGAA  486

Query  506  LFIGYTPQQVAHAQEVKEAIDAGEL  530
            L IGYTP QVAHAQEVKEA+DAGEL
Sbjct  487  LLIGYTPDQVAHAQEVKEAMDAGEL  511


>gi|254776132|ref|ZP_05217648.1| transporter, major facilitator family protein [Mycobacterium 
avium subsp. avium ATCC 25291]
Length=514

 Score =  843 bits (2178),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 457/513 (90%), Positives = 479/513 (94%), Gaps = 0/513 (0%)

Query  18   RPHRPAPMRPPRSEETASERPSRYYPTWLPSRSFIAAVIAIGGMQLLATMDSTVAIVALP  77
            R   PA   P  + ETA +R S+YYP WLPSR FIAAVIAIGGMQLLATMDSTVAIVALP
Sbjct  2    RSTPPAETAPKPAAETAVKRTSKYYPAWLPSRRFIAAVIAIGGMQLLATMDSTVAIVALP  61

Query  78   KIQNELSLSDAGRSWVITAYVLTFGGLMLLGGRLGDTIGRKRTFIVGVALFTISSVLCAV  137
            +IQNELSLSDAGRSWVITAYVLTFGGLMLLGGRLGDTIGRKRTFIVGVALFTISSVLCAV
Sbjct  62   RIQNELSLSDAGRSWVITAYVLTFGGLMLLGGRLGDTIGRKRTFIVGVALFTISSVLCAV  121

Query  138  AWDEATLVIARLSQGVGSAIASPTGLALVATTFPKGPARNAATAVFAAMTAIGSVMGLVV  197
            AWDEAT+VIARLSQGVGSAIASPTGLALVATTFPKGPARN ATAVFAAMTA+GSVMGLVV
Sbjct  122  AWDEATMVIARLSQGVGSAIASPTGLALVATTFPKGPARNFATAVFAAMTAVGSVMGLVV  181

Query  198  GGALTEVSWRWAFLVNVPIGLVMIYLARTALRETNKERMKLDATGAILATLACTAAVFAF  257
            GGALTEVSWR AFLVNVPIGLVM+YLARTALRETN+ERMKLDATGA+LATLACTAAVFAF
Sbjct  182  GGALTEVSWRLAFLVNVPIGLVMMYLARTALRETNRERMKLDATGAVLATLACTAAVFAF  241

Query  258  SIGPEKGWMSGITIGSGLVALAAAVAFVIVERTAENPVVPFHLFRDRNRLVTFSAILLAG  317
            S+GPEKGW+S  TI SG+VAL AA+AFVIVERTAENPVVPF LFRDRNRLVTF AI LAG
Sbjct  242  SMGPEKGWISLTTISSGVVALGAALAFVIVERTAENPVVPFDLFRDRNRLVTFIAIFLAG  301

Query  318  GVMFSLTVCIGLYVQDILGYSALRAGVGFIPFVIAMGIGLGVSSQLVSRFSPRVLTIGGG  377
            GVMF+LTVCIGLYVQDILGYSALRAGVGFIPFVIAMGIGLGVSSQLV+RFSPRVLTI GG
Sbjct  302  GVMFTLTVCIGLYVQDILGYSALRAGVGFIPFVIAMGIGLGVSSQLVARFSPRVLTIAGG  361

Query  378  YLLFGAMLYGSFFMHRGVPYFPNLVMPIVVGGIGIGMAVVPLTLSAIAGVGFDQIGPVSA  437
            YLL  AMLYG + MHRGVPYFPNLV+PIVVGGIGIGMAVVPLTLSAIAGVGFDQIGPVSA
Sbjct  362  YLLVLAMLYGWWCMHRGVPYFPNLVLPIVVGGIGIGMAVVPLTLSAIAGVGFDQIGPVSA  421

Query  438  IALMLQSLGGPLVLAVIQAVITSRTLYLGGTTGPVKFMNDVQLAALDHAYTYGLLWVAGA  497
            + LMLQ+LGGPLVLAVIQAVITSRTLYLGGTTGPVK MND QL ALDH YTYGLLWVAGA
Sbjct  422  VTLMLQNLGGPLVLAVIQAVITSRTLYLGGTTGPVKTMNDAQLQALDHGYTYGLLWVAGA  481

Query  498  AIIVGGMALFIGYTPQQVAHAQEVKEAIDAGEL  530
            A+IVG  ALFIGYTP+QVAHAQEVKEA+DAGEL
Sbjct  482  AVIVGAAALFIGYTPEQVAHAQEVKEAMDAGEL  514


>gi|15827823|ref|NP_302086.1| transmembrane efflux protein [Mycobacterium leprae TN]
 gi|221230300|ref|YP_002503716.1| putative transmembrane efflux protein [Mycobacterium leprae Br4923]
 gi|4455672|emb|CAB36564.1| putative transmembrane efflux protein [Mycobacterium leprae]
 gi|13093375|emb|CAC30513.1| putative transmembrane efflux protein [Mycobacterium leprae]
 gi|219933407|emb|CAR71657.1| putative transmembrane efflux protein [Mycobacterium leprae Br4923]
Length=534

 Score =  834 bits (2154),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 463/535 (87%), Positives = 482/535 (91%), Gaps = 6/535 (1%)

Query  1    MTALNDTERAVRNWTAGRPHRPAPMRPPRSEETASERPSRYYPTWLPSRSF-----IAAV  55
            M  L D ERAV NWTA R  RPAP R  +  E ASER S+Y PT LPS  F     IAAV
Sbjct  1    MVTLYDHERAVHNWTAARSDRPAPSRLTQQVEPASERTSKY-PTLLPSGRFPSGRFIAAV  59

Query  56   IAIGGMQLLATMDSTVAIVALPKIQNELSLSDAGRSWVITAYVLTFGGLMLLGGRLGDTI  115
            I IGGMQLLATMDSTVAIVALPKIQNELSLSDAGRSW ITAYVLTFGGLMLLGGRLGDTI
Sbjct  60   IVIGGMQLLATMDSTVAIVALPKIQNELSLSDAGRSWGITAYVLTFGGLMLLGGRLGDTI  119

Query  116  GRKRTFIVGVALFTISSVLCAVAWDEATLVIARLSQGVGSAIASPTGLALVATTFPKGPA  175
            GRKRTFIVGVALFTISSVLCAVAWDE TLVIARL QG+GSAIASPTGLALVATTF KG A
Sbjct  120  GRKRTFIVGVALFTISSVLCAVAWDEVTLVIARLLQGIGSAIASPTGLALVATTFSKGSA  179

Query  176  RNAATAVFAAMTAIGSVMGLVVGGALTEVSWRWAFLVNVPIGLVMIYLARTALRETNKER  235
            RN ATAVFAAMTAIGSVMGLVVGGALTEVSWR AFLVNVPIGLVMIYLARTAL ET+KER
Sbjct  180  RNTATAVFAAMTAIGSVMGLVVGGALTEVSWRLAFLVNVPIGLVMIYLARTALHETHKER  239

Query  236  MKLDATGAILATLACTAAVFAFSIGPEKGWMSGITIGSGLVALAAAVAFVIVERTAENPV  295
            MKLDA GAILATLACTAAVFAFS+GPEKGW+S  TIGSGLVAL AA+AF +VERTAENPV
Sbjct  240  MKLDAAGAILATLACTAAVFAFSMGPEKGWISLTTIGSGLVALVAAIAFAVVERTAENPV  299

Query  296  VPFHLFRDRNRLVTFSAILLAGGVMFSLTVCIGLYVQDILGYSALRAGVGFIPFVIAMGI  355
            VPF LFRDRNRLVTF AI LAGGV+FSLTV IGLY+QDILGYSALRAG+GFIPFVIAMGI
Sbjct  300  VPFDLFRDRNRLVTFIAIFLAGGVIFSLTVSIGLYIQDILGYSALRAGIGFIPFVIAMGI  359

Query  356  GLGVSSQLVSRFSPRVLTIGGGYLLFGAMLYGSFFMHRGVPYFPNLVMPIVVGGIGIGMA  415
            GLGVSSQLVSRFSPRVLTIGGG+LL  AMLYG  FM+RGVPYFPNL+ PIVVGGIGIGMA
Sbjct  360  GLGVSSQLVSRFSPRVLTIGGGWLLMVAMLYGWAFMNRGVPYFPNLLAPIVVGGIGIGMA  419

Query  416  VVPLTLSAIAGVGFDQIGPVSAIALMLQSLGGPLVLAVIQAVITSRTLYLGGTTGPVKFM  475
            VVPLTLSAIAGVGFD+IGPVSAIALMLQSLGGPLVLAVIQAVITSRTLYLGGTTGPVKFM
Sbjct  420  VVPLTLSAIAGVGFDRIGPVSAIALMLQSLGGPLVLAVIQAVITSRTLYLGGTTGPVKFM  479

Query  476  NDVQLAALDHAYTYGLLWVAGAAIIVGGMALFIGYTPQQVAHAQEVKEAIDAGEL  530
            ND QL ALDH YTYGLLWVAGA +IVG  ALFIGYTP+QVA+AQEVKEA+DAGEL
Sbjct  480  NDAQLRALDHGYTYGLLWVAGAVVIVGVAALFIGYTPEQVAYAQEVKEAVDAGEL  534


>gi|145224626|ref|YP_001135304.1| EmrB/QacA family drug resistance transporter [Mycobacterium gilvum 
PYR-GCK]
 gi|145217112|gb|ABP46516.1| drug resistance transporter, EmrB/QacA subfamily [Mycobacterium 
gilvum PYR-GCK]
Length=543

 Score =  747 bits (1929),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 413/551 (75%), Positives = 458/551 (84%), Gaps = 29/551 (5%)

Query  1    MTALNDTERAVRNWTAGRPHRPAPMRPPRSEETASER--PSR------------------  40
            MTALND ERA          R A  R  R  + AS R  P+R                  
Sbjct  1    MTALNDAERAAI-------QRDAEGRGKRGSDRASGRALPARVTGSGESAGGRGGDAGRR  53

Query  41   -YYPTWLPSRSFIAAVIAIGGMQLLATMDSTVAIVALPKIQNELSLSDAGRSWVITAYVL  99
               P W+PSR F AAVIAIGGMQLLATMDST+AIVALPKIQ+EL LSDAGRSWVITAYVL
Sbjct  54   GRTPAWMPSRRFFAAVIAIGGMQLLATMDSTIAIVALPKIQDELGLSDAGRSWVITAYVL  113

Query  100  TFGGLMLLGGRLGDTIGRKRTFIVGVALFTISSVLCAVAWDEATLVIARLSQGVGSAIAS  159
            TFGGLMLLGGRLGDTIGRKRTFIVGVALFTI+SVLC +AWDEATLVIARL QGVG+AIAS
Sbjct  114  TFGGLMLLGGRLGDTIGRKRTFIVGVALFTIASVLCGIAWDEATLVIARLLQGVGAAIAS  173

Query  160  PTGLALVATTFPKGPARNAATAVFAAMTAIGSVMGLVVGGALTEVSWRWAFLVNVPIGLV  219
            PT LAL+ATTFPKGPARNAATAVFAAMT +GSVMGLVVGGALTEVSWR AFLVNVPIGL+
Sbjct  174  PTALALIATTFPKGPARNAATAVFAAMTGVGSVMGLVVGGALTEVSWRLAFLVNVPIGLI  233

Query  220  MIYLARTALRETNKERMKLDATGAILATLACTAAVFAFSIGPEKGWMSGITIGSGLVALA  279
            MIYLAR  LRETN+ER+KLDA GA+LAT+ CTAAVF FS+GPE GWMS +TIGSG+ A+ 
Sbjct  234  MIYLARKTLRETNRERLKLDAAGALLATMGCTAAVFGFSMGPEAGWMSPVTIGSGIAAVG  293

Query  280  AAVAFVIVERTAENPVVPFHLFRDRNRLVTFSAILLAGGVMFSLTVCIGLYVQDILGYSA  339
              +AF+ VERTAENPVVPF LF DRNR+ TF+A+ LAGGVMF+LTV IGLYVQDI+GYSA
Sbjct  294  CLIAFLWVERTAENPVVPFELFLDRNRVATFAAVFLAGGVMFTLTVTIGLYVQDIMGYSA  353

Query  340  LRAGVGFIPFVIAMGIGLGVSSQLVSRFSPRVLTIGGGYLLFGAMLYGSFFMHRGVPYFP  399
            LRAGVGFIPFVIA+GIGLGVSS LVS++ PRVL IGGG L+  AM+YGS  +   +PYFP
Sbjct  354  LRAGVGFIPFVIALGIGLGVSSALVSKYPPRVLVIGGGVLVLAAMIYGS-TLDANIPYFP  412

Query  400  NLVMPIVVGGIGIGMAVVPLTLSAIAGVGFDQIGPVSAIALMLQSLGGPLVLAVIQAVIT  459
            NLV+PI +GG+GIGM VVPL +SAIAGVGFDQIGPVSAIALMLQ+LGGP+VLA+IQAVIT
Sbjct  413  NLVLPITIGGLGIGMIVVPLMISAIAGVGFDQIGPVSAIALMLQNLGGPVVLAIIQAVIT  472

Query  460  SRTLYLGGTTGPVKFMNDVQLAALDHAYTYGLLWVAGAAIIVGGMALFIGYTPQQVAHAQ  519
            SRTLYLGGTTGPVK MN  Q+ ALD  Y+YGLLWVA  A+IVG +ALFIGYT QQVAHAQ
Sbjct  473  SRTLYLGGTTGPVKDMNAAQMHALDQGYSYGLLWVAAVAVIVGAVALFIGYTAQQVAHAQ  532

Query  520  EVKEAIDAGEL  530
            EVK+AIDAGEL
Sbjct  533  EVKDAIDAGEL  543


>gi|315444958|ref|YP_004077837.1| drug resistance transporter EmrB/QacA subfamily [Mycobacterium 
sp. Spyr1]
 gi|315263261|gb|ADU00003.1| drug resistance transporter, EmrB/QacA subfamily [Mycobacterium 
sp. Spyr1]
Length=543

 Score =  746 bits (1927),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 412/551 (75%), Positives = 458/551 (84%), Gaps = 29/551 (5%)

Query  1    MTALNDTERAVRNWTAGRPHRPAPMRPPRSEETASER--PSR------------------  40
            MTALND ERA          R A  R  R  + AS R  P+R                  
Sbjct  1    MTALNDAERAAI-------QRDAEGRGKRGSDRASGRALPARVTGSGESAGGRGGDAGRR  53

Query  41   -YYPTWLPSRSFIAAVIAIGGMQLLATMDSTVAIVALPKIQNELSLSDAGRSWVITAYVL  99
               P W+PSR F AAVIAIGGMQLLATMDST+AIVALPKIQ+EL LSDAGRSWVITAYVL
Sbjct  54   GRTPAWMPSRRFFAAVIAIGGMQLLATMDSTIAIVALPKIQDELGLSDAGRSWVITAYVL  113

Query  100  TFGGLMLLGGRLGDTIGRKRTFIVGVALFTISSVLCAVAWDEATLVIARLSQGVGSAIAS  159
            TFGGLMLLGGRLGDTIGRKRTFIVGVALFTI+S+LC +AWDEATLVIARL QGVG+AIAS
Sbjct  114  TFGGLMLLGGRLGDTIGRKRTFIVGVALFTIASILCGIAWDEATLVIARLLQGVGAAIAS  173

Query  160  PTGLALVATTFPKGPARNAATAVFAAMTAIGSVMGLVVGGALTEVSWRWAFLVNVPIGLV  219
            PT LAL+ATTFPKGPARNAATAVFAAMT +GSVMGLVVGGALTEVSWR AFLVNVPIGL+
Sbjct  174  PTALALIATTFPKGPARNAATAVFAAMTGVGSVMGLVVGGALTEVSWRLAFLVNVPIGLI  233

Query  220  MIYLARTALRETNKERMKLDATGAILATLACTAAVFAFSIGPEKGWMSGITIGSGLVALA  279
            MIYLAR  LRETN+ER+KLDA GA+LAT+ CTAAVF FS+GPE GWMS +TIGSG+ A+ 
Sbjct  234  MIYLARKTLRETNRERLKLDAAGALLATMGCTAAVFGFSMGPEAGWMSPVTIGSGIAAVG  293

Query  280  AAVAFVIVERTAENPVVPFHLFRDRNRLVTFSAILLAGGVMFSLTVCIGLYVQDILGYSA  339
              +AF+ VERTAENPVVPF LF DRNR+ TF+A+ LAGGVMF+LTV IGLYVQDI+GYSA
Sbjct  294  CLIAFLWVERTAENPVVPFELFLDRNRVATFAAVFLAGGVMFTLTVTIGLYVQDIMGYSA  353

Query  340  LRAGVGFIPFVIAMGIGLGVSSQLVSRFSPRVLTIGGGYLLFGAMLYGSFFMHRGVPYFP  399
            LRAGVGFIPFVIA+GIGLGVSS LVS++ PRVL IGGG L+  AM+YGS  +   +PYFP
Sbjct  354  LRAGVGFIPFVIALGIGLGVSSALVSKYPPRVLVIGGGVLVLAAMIYGS-TLDANIPYFP  412

Query  400  NLVMPIVVGGIGIGMAVVPLTLSAIAGVGFDQIGPVSAIALMLQSLGGPLVLAVIQAVIT  459
            NLV+PI +GG+GIGM VVPL +SAIAGVGFDQIGPVSAIALMLQ+LGGP+VLA+IQAVIT
Sbjct  413  NLVLPITIGGLGIGMIVVPLMISAIAGVGFDQIGPVSAIALMLQNLGGPVVLAIIQAVIT  472

Query  460  SRTLYLGGTTGPVKFMNDVQLAALDHAYTYGLLWVAGAAIIVGGMALFIGYTPQQVAHAQ  519
            SRTLYLGGTTGPVK MN  Q+ ALD  Y+YGLLWVA  A+IVG +ALFIGYT QQVAHAQ
Sbjct  473  SRTLYLGGTTGPVKDMNAAQMHALDQGYSYGLLWVAAVAVIVGAVALFIGYTAQQVAHAQ  532

Query  520  EVKEAIDAGEL  530
            EVK+AIDAGEL
Sbjct  533  EVKDAIDAGEL  543


>gi|120403297|ref|YP_953126.1| major facilitator superfamily transporter [Mycobacterium vanbaalenii 
PYR-1]
 gi|119956115|gb|ABM13120.1| major facilitator superfamily MFS_1 [Mycobacterium vanbaalenii 
PYR-1]
Length=543

 Score =  746 bits (1927),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 414/544 (77%), Positives = 456/544 (84%), Gaps = 15/544 (2%)

Query  1    MTALNDTERAVRNWTA--------GR-PHRPAPMRPPRSEETASERPSRYY-----PTWL  46
            MTALND ERA     A        GR   R  P R P   ETA  R          P W+
Sbjct  1    MTALNDAERAAIQRDAEGSGKRGSGRASDRALPARIPGLGETAGGRGGDGARAGRTPAWV  60

Query  47   PSRSFIAAVIAIGGMQLLATMDSTVAIVALPKIQNELSLSDAGRSWVITAYVLTFGGLML  106
            PSR F AAVIAIGGMQLLATMDST+AIVALPKIQ+EL+LSDAGRSWVITAYVLTFGGLML
Sbjct  61   PSRRFFAAVIAIGGMQLLATMDSTIAIVALPKIQDELNLSDAGRSWVITAYVLTFGGLML  120

Query  107  LGGRLGDTIGRKRTFIVGVALFTISSVLCAVAWDEATLVIARLSQGVGSAIASPTGLALV  166
            LGGRLGDTIGRKRTFIVGV LFTI+SVLC +AWDEATLVIARL QGVG+AIASPT LAL+
Sbjct  121  LGGRLGDTIGRKRTFIVGVTLFTIASVLCGIAWDEATLVIARLLQGVGAAIASPTALALI  180

Query  167  ATTFPKGPARNAATAVFAAMTAIGSVMGLVVGGALTEVSWRWAFLVNVPIGLVMIYLART  226
            ATTFPKGPARNAATAVFAAMT +GSVMGLVVGGALTEVSWR AFLVNVPIGL+MIYLAR 
Sbjct  181  ATTFPKGPARNAATAVFAAMTGVGSVMGLVVGGALTEVSWRLAFLVNVPIGLIMIYLARK  240

Query  227  ALRETNKERMKLDATGAILATLACTAAVFAFSIGPEKGWMSGITIGSGLVALAAAVAFVI  286
             LRETNKER+KLDA GA+LAT+ CTAAVFAFS+GPE GW S +T+ S + A+   +AF+ 
Sbjct  241  TLRETNKERLKLDAAGALLATMGCTAAVFAFSMGPESGWASPVTVASAVAAVGCLLAFLW  300

Query  287  VERTAENPVVPFHLFRDRNRLVTFSAILLAGGVMFSLTVCIGLYVQDILGYSALRAGVGF  346
            VERTAENPVVPF LF DRNR+ TF+A+ LAGGVMF+LTV IGLYVQDI+GYSALRAG+GF
Sbjct  301  VERTAENPVVPFALFHDRNRVATFAAVFLAGGVMFTLTVTIGLYVQDIMGYSALRAGIGF  360

Query  347  IPFVIAMGIGLGVSSQLVSRFSPRVLTIGGGYLLFGAMLYGSFFMHRGVPYFPNLVMPIV  406
            IPFVIA+GIGLG+SS LVS+F PRVL IGGG L+  AM+YGS  +  G+PYFPNLV+PI 
Sbjct  361  IPFVIALGIGLGLSSALVSKFPPRVLVIGGGVLVLAAMIYGS-TLDAGIPYFPNLVLPIT  419

Query  407  VGGIGIGMAVVPLTLSAIAGVGFDQIGPVSAIALMLQSLGGPLVLAVIQAVITSRTLYLG  466
            +GG GIGM VVPL +SAIAGVGFDQIGPVSAIALMLQ+LGGP+VLAVIQAVITSRTLYLG
Sbjct  420  IGGFGIGMIVVPLMISAIAGVGFDQIGPVSAIALMLQNLGGPVVLAVIQAVITSRTLYLG  479

Query  467  GTTGPVKFMNDVQLAALDHAYTYGLLWVAGAAIIVGGMALFIGYTPQQVAHAQEVKEAID  526
            GTTGPVK MN  QL ALD  Y+YGLLWVA  A+IVGG ALFIGYT +QVAHAQEVK+AID
Sbjct  480  GTTGPVKDMNAAQLHALDQGYSYGLLWVAAVAVIVGGAALFIGYTAEQVAHAQEVKDAID  539

Query  527  AGEL  530
            AGEL
Sbjct  540  AGEL  543


>gi|108799042|ref|YP_639239.1| major facilitator transporter [Mycobacterium sp. MCS]
 gi|119868157|ref|YP_938109.1| major facilitator superfamily transporter [Mycobacterium sp. 
KMS]
 gi|126434645|ref|YP_001070336.1| major facilitator transporter [Mycobacterium sp. JLS]
 gi|108769461|gb|ABG08183.1| major facilitator superfamily MFS_1 [Mycobacterium sp. MCS]
 gi|119694246|gb|ABL91319.1| major facilitator superfamily MFS_1 [Mycobacterium sp. KMS]
 gi|126234445|gb|ABN97845.1| major facilitator superfamily MFS_1 [Mycobacterium sp. JLS]
Length=529

 Score =  728 bits (1878),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 403/540 (75%), Positives = 449/540 (84%), Gaps = 21/540 (3%)

Query  1    MTALNDTERAV----------RNWTAGRPHRPAPMRPPRSEETASERPSRYYPTWLPSRS  50
            MTALND ERA           R  T G+P   AP    R++ +          TWLPSR 
Sbjct  1    MTALNDAERAAMFRDAEGRSKRAQTTGQPMGSAPTSVGRAKTS----------TWLPSRR  50

Query  51   FIAAVIAIGGMQLLATMDSTVAIVALPKIQNELSLSDAGRSWVITAYVLTFGGLMLLGGR  110
            F AAVIAI GMQL+ATMD T+AIVALPKIQNEL LSDAGRSWVITAYVLTFGGLMLLGGR
Sbjct  51   FFAAVIAIAGMQLMATMDGTIAIVALPKIQNELMLSDAGRSWVITAYVLTFGGLMLLGGR  110

Query  111  LGDTIGRKRTFIVGVALFTISSVLCAVAWDEATLVIARLSQGVGSAIASPTGLALVATTF  170
            LGDTIGRKRTFIVGVALFTI+S+LC +AWDE TLVIARL QGVG+AIASPT LALVATTF
Sbjct  111  LGDTIGRKRTFIVGVALFTIASILCGIAWDEVTLVIARLLQGVGAAIASPTALALVATTF  170

Query  171  PKGPARNAATAVFAAMTAIGSVMGLVVGGALTEVSWRWAFLVNVPIGLVMIYLARTALRE  230
            PKGPARNAATAVFAAMT +GSVMGLVVGGALTEVSWR AFLVN PIGL+++YLA TALRE
Sbjct  171  PKGPARNAATAVFAAMTGVGSVMGLVVGGALTEVSWRLAFLVNAPIGLLIVYLAHTALRE  230

Query  231  TNKERMKLDATGAILATLACTAAVFAFSIGPEKGWMSGITIGSGLVALAAAVAFVIVERT  290
            T+KER+KLDATGA+LATL CTAAVF FS+GPEKGW+S +TI S   A    +AF+ VER+
Sbjct  231  THKERLKLDATGALLATLGCTAAVFGFSMGPEKGWLSSVTIASIAAAGVFLLAFIFVERS  290

Query  291  AENPVVPFHLFRDRNRLVTFSAILLAGGVMFSLTVCIGLYVQDILGYSALRAGVGFIPFV  350
            AENPVVPF LF+DRNRL TF+A+ LAGGVMF+L+V IGLYVQDILGYS LRAG+GFIPF 
Sbjct  291  AENPVVPFVLFKDRNRLATFAAVFLAGGVMFTLSVLIGLYVQDILGYSPLRAGIGFIPFA  350

Query  351  IAMGIGLGVSSQLVSRFSPRVLTIGGGYLLFGAMLYGSFFMHRGVPYFPNLVMPIVVGGI  410
            IAMGIGL VSSQLV    PR+L I GG L+ GAM+YGS  ++ G+PYFPNLV+P+VVGGI
Sbjct  351  IAMGIGLAVSSQLVPILPPRILVISGGVLVLGAMIYGS-TLNSGIPYFPNLVIPLVVGGI  409

Query  411  GIGMAVVPLTLSAIAGVGFDQIGPVSAIALMLQSLGGPLVLAVIQAVITSRTLYLGGTTG  470
            GIG+  V L LSAIAGVGFDQIGPVSAI LMLQ+LGGP+VLAVIQAVITSRTLYLGGTTG
Sbjct  410  GIGIIFVALMLSAIAGVGFDQIGPVSAITLMLQNLGGPVVLAVIQAVITSRTLYLGGTTG  469

Query  471  PVKFMNDVQLAALDHAYTYGLLWVAGAAIIVGGMALFIGYTPQQVAHAQEVKEAIDAGEL  530
            PVK M+  Q+AALD  YTYGLLWVA  A++VGG AL IGYT QQVAHAQEVK+A+DAGEL
Sbjct  470  PVKNMDGTQIAALDAGYTYGLLWVAAVAVLVGGAALLIGYTSQQVAHAQEVKDALDAGEL  529


>gi|333991210|ref|YP_004523824.1| integral membrane efflux protein EfpA [Mycobacterium sp. JDM601]
 gi|333487178|gb|AEF36570.1| integral membrane efflux protein EfpA [Mycobacterium sp. JDM601]
Length=485

 Score =  712 bits (1837),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 382/485 (79%), Positives = 427/485 (89%), Gaps = 1/485 (0%)

Query  46   LPSRSFIAAVIAIGGMQLLATMDSTVAIVALPKIQNELSLSDAGRSWVITAYVLTFGGLM  105
            LPSR FI AVIAIGGMQLLATMDST+AIVALPKIQN+L LSDAGR WVI+AYVLTFGGLM
Sbjct  2    LPSRRFIYAVIAIGGMQLLATMDSTIAIVALPKIQNDLGLSDAGRGWVISAYVLTFGGLM  61

Query  106  LLGGRLGDTIGRKRTFIVGVALFTISSVLCAVAWDEATLVIARLSQGVGSAIASPTGLAL  165
            LLGGRLGDTIGRKRTFI GVALFTI+SVLCA AWD  TLVIARL QGVGSAIASPT LAL
Sbjct  62   LLGGRLGDTIGRKRTFISGVALFTIASVLCAAAWDAPTLVIARLLQGVGSAIASPTALAL  121

Query  166  VATTFPKGPARNAATAVFAAMTAIGSVMGLVVGGALTEVSWRWAFLVNVPIGLVMIYLAR  225
            +ATTFPKGPARNAATAVF AMTA+GSVMGLV GGALTEVSWR AF +NVPIG++MIYLAR
Sbjct  122  IATTFPKGPARNAATAVFGAMTAVGSVMGLVAGGALTEVSWRLAFGINVPIGVLMIYLAR  181

Query  226  TALRETNKERMKLDATGAILATLACTAAVFAFSIGPEKGWMSGITIGSGLVALAAAVAFV  285
            TAL ET +ERMKLDA GA+LATL CTAAVFAF+IGPEKGW+S ITIGSG+VA+ A +AF 
Sbjct  182  TALTETQRERMKLDAAGALLATLGCTAAVFAFTIGPEKGWISVITIGSGVVAVVALLAFA  241

Query  286  IVERTAENPVVPFHLFRDRNRLVTFSAILLAGGVMFSLTVCIGLYVQDILGYSALRAGVG  345
            +VERTAENPVVPF LFRDRNRL+TF+AI LAGGV+F+LTV IGLYVQD++GYSALRAGVG
Sbjct  242  LVERTAENPVVPFSLFRDRNRLLTFAAIFLAGGVLFTLTVTIGLYVQDLMGYSALRAGVG  301

Query  346  FIPFVIAMGIGLGVSSQLVSRFSPRVLTIGGGYLLFGAMLYGSFFMHRGVPYFPNLVMPI  405
            FIPFVI +G+GLGVSSQLV  F PRVL I GG +L GAM+YGS  + R + YFPN V  I
Sbjct  302  FIPFVIGLGVGLGVSSQLVRLFPPRVLVISGGVVLLGAMIYGS-TIDRDIAYFPNFVTLI  360

Query  406  VVGGIGIGMAVVPLTLSAIAGVGFDQIGPVSAIALMLQSLGGPLVLAVIQAVITSRTLYL  465
            V+GG+GIG+ VVPLTLSAIAGVGFDQIGP SAIALMLQ+LGGP+VLAV+QAVITSRTLYL
Sbjct  361  VLGGLGIGVIVVPLTLSAIAGVGFDQIGPTSAIALMLQNLGGPIVLAVVQAVITSRTLYL  420

Query  466  GGTTGPVKFMNDVQLAALDHAYTYGLLWVAGAAIIVGGMALFIGYTPQQVAHAQEVKEAI  525
            GGT  PVK M+  Q+AALD  YTYGLLWVAG A++VG ++L IGY+ +QVAHAQE ++A 
Sbjct  421  GGTNMPVKTMSPTQIAALDAGYTYGLLWVAGVAVLVGAISLLIGYSAKQVAHAQEAQDAF  480

Query  526  DAGEL  530
             AG L
Sbjct  481  GAGNL  485


>gi|118471791|ref|YP_886956.1| efflux protein [Mycobacterium smegmatis str. MC2 155]
 gi|118173078|gb|ABK73974.1| efflux protein [Mycobacterium smegmatis str. MC2 155]
Length=515

 Score =  687 bits (1772),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 408/531 (77%), Positives = 448/531 (85%), Gaps = 25/531 (4%)

Query  1    MTALNDTERAV-RNWTAGRPHRPAPMRPPRSEETASERPSRYYPTWLPSRSFIAAVIAIG  59
            MTALND ERA  R   A R                        P+W PS  F++AVIAIG
Sbjct  1    MTALNDAERAAARVGLAAR-----------------------LPSWFPSWGFLSAVIAIG  37

Query  60   GMQLLATMDSTVAIVALPKIQNELSLSDAGRSWVITAYVLTFGGLMLLGGRLGDTIGRKR  119
            GMQLLATMDSTVAIVALPKIQ+ELSLSDAGRSWVITAYVLTFGGLMLLGGRLGDTIGRKR
Sbjct  38   GMQLLATMDSTVAIVALPKIQDELSLSDAGRSWVITAYVLTFGGLMLLGGRLGDTIGRKR  97

Query  120  TFIVGVALFTISSVLCAVAWDEATLVIARLSQGVGSAIASPTGLALVATTFPKGPARNAA  179
            TFIVGV LFTI+SVLC +AW+E TLV ARL QGVG+AIASPTGLALVATTFPKGPARNAA
Sbjct  98   TFIVGVMLFTIASVLCGIAWNETTLVTARLLQGVGAAIASPTGLALVATTFPKGPARNAA  157

Query  180  TAVFAAMTAIGSVMGLVVGGALTEVSWRWAFLVNVPIGLVMIYLARTALRETNKERMKLD  239
            TAVF AMTAIGSVMGLVVGGALTEVSWRWAFLVNVPIGLVM+YLARTAL+ETN+ERMKLD
Sbjct  158  TAVFGAMTAIGSVMGLVVGGALTEVSWRWAFLVNVPIGLVMVYLARTALQETNRERMKLD  217

Query  240  ATGAILATLACTAAVFAFSIGPEKGWMSGITIGSGLVALAAAVAFVIVERTAENPVVPFH  299
            A GA+LATLACTAAVFAF+ GPE GW++ IT+ SG  AL   +AF+I ER AENPVVPF 
Sbjct  218  AAGALLATLACTAAVFAFTQGPESGWLAPITLASGAAALVFGLAFLIAERNAENPVVPFA  277

Query  300  LFRDRNRLVTFSAILLAGGVMFSLTVCIGLYVQDILGYSALRAGVGFIPFVIAMGIGLGV  359
            LFR+RNR+ TF+AI LAGGV+F+LTV IGLYVQDILGYSALRAGVGFIPFVI MGIGLG 
Sbjct  278  LFRERNRVATFAAIFLAGGVLFTLTVLIGLYVQDILGYSALRAGVGFIPFVIGMGIGLGA  337

Query  360  SSQLVSRFSPRVLTIGGGYLLFGAMLYGSFFMHRGVPYFPNLVMPIVVGGIGIGMAVVPL  419
            +SQLV    PRVL I GG L+ GAM+YGS  +HRG+PYFPNLV+PI +GGIGIG  VVPL
Sbjct  338  ASQLVRSIPPRVLVIAGGILVLGAMIYGS-TLHRGIPYFPNLVLPITIGGIGIGTIVVPL  396

Query  420  TLSAIAGVGFDQIGPVSAIALMLQSLGGPLVLAVIQAVITSRTLYLGGTTGPVKFMNDVQ  479
            TLSAIAGV  D+IGP SAIALMLQ+LGGPLVLAVIQAVITSRTL+LGGTTGPVK MND Q
Sbjct  397  TLSAIAGVNLDRIGPASAIALMLQNLGGPLVLAVIQAVITSRTLFLGGTTGPVKAMNDEQ  456

Query  480  LAALDHAYTYGLLWVAGAAIIVGGMALFIGYTPQQVAHAQEVKEAIDAGEL  530
            + ALD AYTYGLLWVA  A++VG  ALFIGYT QQVAHAQ+VK+A+DAGE+
Sbjct  457  IGALDAAYTYGLLWVAAVAVLVGAAALFIGYTSQQVAHAQDVKDAMDAGEI  507


>gi|254819676|ref|ZP_05224677.1| EfpA_1 [Mycobacterium intracellulare ATCC 13950]
Length=502

 Score =  592 bits (1525),  Expect = 7e-167, Method: Compositional matrix adjust.
 Identities = 333/500 (67%), Positives = 394/500 (79%), Gaps = 2/500 (0%)

Query  32   ETASERPS-RYYPTWLPSRSFIAAVIAIGGMQLLATMDSTVAIVALPKIQNELSLSDAGR  90
            + ++ RP+ R  P  L SR F+A V+AIGGMQL+  MD  VAI ALP+IQNEL LSDAGR
Sbjct  4    KPSAPRPAKRRLPPLLRSRPFVAVVVAIGGMQLMVAMDGPVAIFALPRIQNELGLSDAGR  63

Query  91   SWVITAYVLTFGGLMLLGGRLGDTIGRKRTFIVGVALFTISSVLCAVAWDEATLVIARLS  150
            SWVITAY+LTFGGLMLLGGRLGDTIGRKR FIVGVALFT +S LC +AWD  TL+ ARL 
Sbjct  64   SWVITAYMLTFGGLMLLGGRLGDTIGRKRAFIVGVALFTFASTLCGIAWDGGTLITARLL  123

Query  151  QGVGSAIASPTGLALVATTFPKGPARNAATAVFAAMTAIGSVMGLVVGGALTEVSWRWAF  210
             G  SAI +PT LAL+ATTFP+G ARN AT VF AM+ +G V+GLVVGGALT+VSWR AF
Sbjct  124  HGAASAIMAPTNLALIATTFPRGSARNVATGVFGAMSGLGGVLGLVVGGALTDVSWRLAF  183

Query  211  LVNVPIGLVMIYLARTALRETNKERMKLDATGAILATLACTAAVFAFSIGPEKGWMSGIT  270
            LVNVPIGL +I LA   L+ET KERMKLDATGA LATL+CTAAVF  S+GPE GW S IT
Sbjct  184  LVNVPIGLAVICLAVIMLQETQKERMKLDATGAALATLSCTAAVFGLSMGPEHGWQSAIT  243

Query  271  IGSGLVALAAAVAFVIVERTAENPVVPFHLFRDRNRLVTFSAILLAGGVMFSLTVCIGLY  330
            IGSGLVALAA VAFV+ ERTAENP+VPF LF DRNRL  F+A+ L GGV+FSLTV +G+Y
Sbjct  244  IGSGLVALAALVAFVVAERTAENPIVPFGLFFDRNRLAAFAAMFLGGGVLFSLTVLVGMY  303

Query  331  VQDILGYSALRAGVGFIPFVIAMGIGLGVSSQLVSRFSPRVLTIGGGYLLFGAMLYGSFF  390
            VQ ++GYS LRAGV FIPF I + IG+G + +LV  F PRV+ +    L+  A LYG+  
Sbjct  304  VQTVMGYSPLRAGVAFIPFGIGVAIGVGAAPKLVMWFPPRVVVLASSGLILIATLYGA-T  362

Query  391  MHRGVPYFPNLVMPIVVGGIGIGMAVVPLTLSAIAGVGFDQIGPVSAIALMLQSLGGPLV  450
            ++ G+PYFPNL++P+ +G +GIG   VPLTLS IA VG D+IGP SAIA+MLQ+LGGPLV
Sbjct  363  LNAGIPYFPNLLVPLSIGALGIGAIFVPLTLSVIACVGSDRIGPTSAIAVMLQTLGGPLV  422

Query  451  LAVIQAVITSRTLYLGGTTGPVKFMNDVQLAALDHAYTYGLLWVAGAAIIVGGMALFIGY  510
            L +IQA ITS TL LGGT GPVK MN  QL ALD  YTYGLLW+AG  +++G +AL IGY
Sbjct  423  LVIIQAAITSHTLRLGGTLGPVKSMNAAQLHALDRGYTYGLLWLAGVVVLLGAVALLIGY  482

Query  511  TPQQVAHAQEVKEAIDAGEL  530
            T  QVA AQEV++A+DAGE+
Sbjct  483  TAAQVARAQEVRKAVDAGEI  502


>gi|342859837|ref|ZP_08716490.1| EfpA_1 [Mycobacterium colombiense CECT 3035]
 gi|342132969|gb|EGT86189.1| EfpA_1 [Mycobacterium colombiense CECT 3035]
Length=503

 Score =  575 bits (1482),  Expect = 6e-162, Method: Compositional matrix adjust.
 Identities = 334/500 (67%), Positives = 392/500 (79%), Gaps = 2/500 (0%)

Query  32   ETASERPS-RYYPTWLPSRSFIAAVIAIGGMQLLATMDSTVAIVALPKIQNELSLSDAGR  90
            E  + RP+ R+ P  L SR F+A ++AIGGMQL+  MD  VAI ALP+IQNEL LSDAGR
Sbjct  5    EPTTLRPTKRHVPALLRSRRFVAVIVAIGGMQLMVAMDGPVAIFALPRIQNELGLSDAGR  64

Query  91   SWVITAYVLTFGGLMLLGGRLGDTIGRKRTFIVGVALFTISSVLCAVAWDEATLVIARLS  150
            SWVITAY+LTFGGLMLLGGRLGDTIGRKR FI GVALFT +S LC +AWD  TL+ ARL 
Sbjct  65   SWVITAYMLTFGGLMLLGGRLGDTIGRKRAFIAGVALFTFASTLCGIAWDGGTLISARLL  124

Query  151  QGVGSAIASPTGLALVATTFPKGPARNAATAVFAAMTAIGSVMGLVVGGALTEVSWRWAF  210
             G  SAI +PT LAL+ATTFP+G ARN AT VF AM+ +G V+GLVVGGALT+VSWR AF
Sbjct  125  HGAASAIMAPTNLALIATTFPRGSARNVATGVFGAMSGLGGVLGLVVGGALTDVSWRLAF  184

Query  211  LVNVPIGLVMIYLARTALRETNKERMKLDATGAILATLACTAAVFAFSIGPEKGWMSGIT  270
            LVNVPIGL +I LA   L+ET KERMKLDATGA LATL+CTAAVF  S+GPE+GW+S IT
Sbjct  185  LVNVPIGLAVICLAVIMLQETQKERMKLDATGAALATLSCTAAVFGLSMGPEQGWLSPIT  244

Query  271  IGSGLVALAAAVAFVIVERTAENPVVPFHLFRDRNRLVTFSAILLAGGVMFSLTVCIGLY  330
            IGSG VA+AA VAFV+ ERTAENP+VPF LF DRNRL  F+A+ L GGV+FSLTV +GLY
Sbjct  245  IGSGSVAVAAFVAFVLAERTAENPIVPFGLFLDRNRLAAFAAMFLGGGVLFSLTVVVGLY  304

Query  331  VQDILGYSALRAGVGFIPFVIAMGIGLGVSSQLVSRFSPRVLTIGGGYLLFGAMLYGSFF  390
            VQ ++GYS L AGV FIPF I + IG+GV+S+LV  + PRV+ +    L+  A LYG+  
Sbjct  305  VQTVMGYSPLHAGVAFIPFGIGVAIGVGVASKLVMWWPPRVVVLASCGLILVATLYGA-T  363

Query  391  MHRGVPYFPNLVMPIVVGGIGIGMAVVPLTLSAIAGVGFDQIGPVSAIALMLQSLGGPLV  450
            ++ G+PYFPNLV+P+ +G IGIG   VPLTLS IA VG D+IGP SAIA+MLQ+LGGPLV
Sbjct  364  LNAGIPYFPNLVLPLSIGAIGIGAIFVPLTLSVIASVGVDRIGPTSAIAVMLQTLGGPLV  423

Query  451  LAVIQAVITSRTLYLGGTTGPVKFMNDVQLAALDHAYTYGLLWVAGAAIIVGGMALFIGY  510
            L VIQA ITS TL LGGT GPV  MN  QL ALD  YTYGLLW+AG  +++GG+AL IGY
Sbjct  424  LVVIQAAITSHTLRLGGTLGPVNSMNAAQLHALDRGYTYGLLWLAGVVVLLGGVALLIGY  483

Query  511  TPQQVAHAQEVKEAIDAGEL  530
            T  QVA AQE KEA DAG +
Sbjct  484  TAAQVARAQEAKEAADAGAM  503


>gi|336462020|gb|EGO40869.1| arabinose efflux permease family protein [Mycobacterium avium 
subsp. paratuberculosis S397]
Length=492

 Score =  573 bits (1478),  Expect = 2e-161, Method: Compositional matrix adjust.
 Identities = 332/487 (69%), Positives = 388/487 (80%), Gaps = 1/487 (0%)

Query  44   TWLPSRSFIAAVIAIGGMQLLATMDSTVAIVALPKIQNELSLSDAGRSWVITAYVLTFGG  103
            T L SR F+A ++AIGGMQL+  MD  VA+ ALPKIQNE+ LSDA RSWVITAY+LTFGG
Sbjct  7    TRLWSRQFVAVIVAIGGMQLMVAMDGPVAVFALPKIQNEMGLSDAARSWVITAYMLTFGG  66

Query  104  LMLLGGRLGDTIGRKRTFIVGVALFTISSVLCAVAWDEATLVIARLSQGVGSAIASPTGL  163
            LMLLGGRLGDTIGRKR F+VGVALFT +S LC +AW   TL+ ARL  G  +AI +PT L
Sbjct  67   LMLLGGRLGDTIGRKRAFLVGVALFTFASGLCGIAWAGGTLIAARLLHGAAAAIIAPTNL  126

Query  164  ALVATTFPKGPARNAATAVFAAMTAIGSVMGLVVGGALTEVSWRWAFLVNVPIGLVMIYL  223
            AL+ATTFP+G ARNAATAVF AMT +G V+GLVVGGALT+VSWR AFLVNVPIGL +IYL
Sbjct  127  ALIATTFPRGSARNAATAVFGAMTGLGGVLGLVVGGALTDVSWRLAFLVNVPIGLAVIYL  186

Query  224  ARTALRETNKERMKLDATGAILATLACTAAVFAFSIGPEKGWMSGITIGSGLVALAAAVA  283
                 +ET  ER+KLD TGA+LAT+  TAAVF  S+GPE GW S ITIGSG+VALAA VA
Sbjct  187  VLITRQETQTERIKLDVTGAVLATVTGTAAVFGISMGPEAGWRSPITIGSGVVALAAFVA  246

Query  284  FVIVERTAENPVVPFHLFRDRNRLVTFSAILLAGGVMFSLTVCIGLYVQDILGYSALRAG  343
            FV+VERTAENP+VPF+LF DRNRL  F+A+ LAGGV F+LTV +GLYVQ ++GYS LRAG
Sbjct  247  FVVVERTAENPIVPFNLFLDRNRLAAFAAMFLAGGVFFTLTVLVGLYVQTMMGYSPLRAG  306

Query  344  VGFIPFVIAMGIGLGVSSQLVSRFSPRVLTIGGGYLLFGAMLYGSFFMHRGVPYFPNLVM  403
            V FIPF +AM IG+GV+S+LV+ F PRV+ I  G L+ GA LYGS F +RG+PYFPNLV+
Sbjct  307  VAFIPFGLAMAIGVGVASKLVTWFPPRVVVIASGGLILGATLYGSTF-NRGMPYFPNLVV  365

Query  404  PIVVGGIGIGMAVVPLTLSAIAGVGFDQIGPVSAIALMLQSLGGPLVLAVIQAVITSRTL  463
            P++V  IGIG   V LTLS IA V  D+IGP SAIA+MLQ+LGGPLVL V+Q  ITS  L
Sbjct  366  PLIVCAIGIGAVFVTLTLSVIASVDVDRIGPTSAIAVMLQTLGGPLVLVVVQVAITSHAL  425

Query  464  YLGGTTGPVKFMNDVQLAALDHAYTYGLLWVAGAAIIVGGMALFIGYTPQQVAHAQEVKE  523
             LGGT GPVK MN  QL ALD  YTYGLLW+AG   ++GG+AL IGYT  QVA AQEVK+
Sbjct  426  RLGGTLGPVKSMNAAQLHALDRGYTYGLLWLAGVVALLGGVALLIGYTAAQVARAQEVKK  485

Query  524  AIDAGEL  530
            A+DAGEL
Sbjct  486  AVDAGEL  492


>gi|41407966|ref|NP_960802.1| EfpA_1 [Mycobacterium avium subsp. paratuberculosis K-10]
 gi|41396320|gb|AAS04185.1| EfpA_1 [Mycobacterium avium subsp. paratuberculosis K-10]
Length=494

 Score =  573 bits (1478),  Expect = 2e-161, Method: Compositional matrix adjust.
 Identities = 332/487 (69%), Positives = 388/487 (80%), Gaps = 1/487 (0%)

Query  44   TWLPSRSFIAAVIAIGGMQLLATMDSTVAIVALPKIQNELSLSDAGRSWVITAYVLTFGG  103
            T L SR F+A ++AIGGMQL+  MD  VA+ ALPKIQNE+ LSDA RSWVITAY+LTFGG
Sbjct  9    TRLWSRQFVAVIVAIGGMQLMVAMDGPVAVFALPKIQNEMGLSDAARSWVITAYMLTFGG  68

Query  104  LMLLGGRLGDTIGRKRTFIVGVALFTISSVLCAVAWDEATLVIARLSQGVGSAIASPTGL  163
            LMLLGGRLGDTIGRKR F+VGVALFT +S LC +AW   TL+ ARL  G  +AI +PT L
Sbjct  69   LMLLGGRLGDTIGRKRAFLVGVALFTFASGLCGIAWAGGTLIAARLLHGAAAAIIAPTNL  128

Query  164  ALVATTFPKGPARNAATAVFAAMTAIGSVMGLVVGGALTEVSWRWAFLVNVPIGLVMIYL  223
            AL+ATTFP+G ARNAATAVF AMT +G V+GLVVGGALT+VSWR AFLVNVPIGL +IYL
Sbjct  129  ALIATTFPRGSARNAATAVFGAMTGLGGVLGLVVGGALTDVSWRLAFLVNVPIGLAVIYL  188

Query  224  ARTALRETNKERMKLDATGAILATLACTAAVFAFSIGPEKGWMSGITIGSGLVALAAAVA  283
                 +ET  ER+KLD TGA+LAT+  TAAVF  S+GPE GW S ITIGSG+VALAA VA
Sbjct  189  VLITRQETQTERIKLDVTGAVLATVTGTAAVFGISMGPEAGWRSPITIGSGVVALAAFVA  248

Query  284  FVIVERTAENPVVPFHLFRDRNRLVTFSAILLAGGVMFSLTVCIGLYVQDILGYSALRAG  343
            FV+VERTAENP+VPF+LF DRNRL  F+A+ LAGGV F+LTV +GLYVQ ++GYS LRAG
Sbjct  249  FVVVERTAENPIVPFNLFLDRNRLAAFAAMFLAGGVFFTLTVLVGLYVQTMMGYSPLRAG  308

Query  344  VGFIPFVIAMGIGLGVSSQLVSRFSPRVLTIGGGYLLFGAMLYGSFFMHRGVPYFPNLVM  403
            V FIPF +AM IG+GV+S+LV+ F PRV+ I  G L+ GA LYGS F +RG+PYFPNLV+
Sbjct  309  VAFIPFGLAMAIGVGVASKLVTWFPPRVVVIASGGLILGATLYGSTF-NRGMPYFPNLVV  367

Query  404  PIVVGGIGIGMAVVPLTLSAIAGVGFDQIGPVSAIALMLQSLGGPLVLAVIQAVITSRTL  463
            P++V  IGIG   V LTLS IA V  D+IGP SAIA+MLQ+LGGPLVL V+Q  ITS  L
Sbjct  368  PLIVCAIGIGAVFVTLTLSVIASVDVDRIGPTSAIAVMLQTLGGPLVLVVVQVAITSHAL  427

Query  464  YLGGTTGPVKFMNDVQLAALDHAYTYGLLWVAGAAIIVGGMALFIGYTPQQVAHAQEVKE  523
             LGGT GPVK MN  QL ALD  YTYGLLW+AG   ++GG+AL IGYT  QVA AQEVK+
Sbjct  428  RLGGTLGPVKSMNAAQLHALDRGYTYGLLWLAGVVALLGGVALLIGYTAAQVARAQEVKK  487

Query  524  AIDAGEL  530
            A+DAGEL
Sbjct  488  AVDAGEL  494


>gi|118467314|ref|YP_881570.1| transporter, major facilitator family protein [Mycobacterium 
avium 104]
 gi|118168601|gb|ABK69498.1| transporter, major facilitator family protein [Mycobacterium 
avium 104]
Length=495

 Score =  568 bits (1463),  Expect = 1e-159, Method: Compositional matrix adjust.
 Identities = 331/488 (68%), Positives = 387/488 (80%), Gaps = 2/488 (0%)

Query  44   TWLPSRSFIAAVIAIGGMQLLATMDSTVAIVALPKIQNELSLSDAGRSWVITAYVLTFGG  103
            T L SR F+A ++AIGGMQL+  MD  VA+ ALPKIQNE+ LSDA RSWVITAY+LTFGG
Sbjct  9    TRLWSRQFVAVIVAIGGMQLMVAMDGPVAVFALPKIQNEMGLSDAARSWVITAYMLTFGG  68

Query  104  LMLLGGRLGDTIGRKRT-FIVGVALFTISSVLCAVAWDEATLVIARLSQGVGSAIASPTG  162
            LMLLGGRLGDTIGRKR  F+VGVALFT +S LC +AW   TL+ ARL  G  +AI +PT 
Sbjct  69   LMLLGGRLGDTIGRKRAAFLVGVALFTFASGLCGIAWAGGTLIAARLLHGAAAAIIAPTN  128

Query  163  LALVATTFPKGPARNAATAVFAAMTAIGSVMGLVVGGALTEVSWRWAFLVNVPIGLVMIY  222
            LAL+ATTFP+G ARNAATAVF AMT +G V+GLVVGGALT+VSWR AFLVNVPIGL +IY
Sbjct  129  LALIATTFPRGSARNAATAVFGAMTGLGGVLGLVVGGALTDVSWRLAFLVNVPIGLAVIY  188

Query  223  LARTALRETNKERMKLDATGAILATLACTAAVFAFSIGPEKGWMSGITIGSGLVALAAAV  282
            L     +ET  ER+KLD TGA+LAT+  TAAVF  S+GPE GW S ITIGSG+VALAA V
Sbjct  189  LVLITRQETQTERIKLDVTGAVLATVTGTAAVFGISMGPEAGWRSPITIGSGVVALAAFV  248

Query  283  AFVIVERTAENPVVPFHLFRDRNRLVTFSAILLAGGVMFSLTVCIGLYVQDILGYSALRA  342
            AFV+VERTAENP+VPF+LF DRNRL  F+A+ LAGGV F+LTV +GLYVQ ++GYS LRA
Sbjct  249  AFVVVERTAENPIVPFNLFLDRNRLAAFAAMFLAGGVFFTLTVLVGLYVQTMMGYSPLRA  308

Query  343  GVGFIPFVIAMGIGLGVSSQLVSRFSPRVLTIGGGYLLFGAMLYGSFFMHRGVPYFPNLV  402
            GV FIPF +AM IG+GV+S+LV+ F PRV+ I  G L+ GA LYGS F +RG+PYFPNLV
Sbjct  309  GVAFIPFGLAMAIGVGVASKLVTWFPPRVVVIASGGLILGATLYGSTF-NRGMPYFPNLV  367

Query  403  MPIVVGGIGIGMAVVPLTLSAIAGVGFDQIGPVSAIALMLQSLGGPLVLAVIQAVITSRT  462
            +P++V  IGIG   V LTLS IA V  D+IGP SAIA+MLQ+LGGPLVL V+Q  ITS  
Sbjct  368  VPLIVCAIGIGAVFVTLTLSVIASVDVDRIGPTSAIAVMLQTLGGPLVLVVVQVAITSHA  427

Query  463  LYLGGTTGPVKFMNDVQLAALDHAYTYGLLWVAGAAIIVGGMALFIGYTPQQVAHAQEVK  522
            L LGGT GPVK MN  QL ALD  YTYGLLW+AG   ++GG+ L IGYT  QVA AQEVK
Sbjct  428  LRLGGTLGPVKSMNAAQLHALDRGYTYGLLWLAGVVALLGGVTLLIGYTAAQVARAQEVK  487

Query  523  EAIDAGEL  530
            +A+DAGEL
Sbjct  488  KAVDAGEL  495


>gi|254775040|ref|ZP_05216556.1| transporter, major facilitator family protein [Mycobacterium 
avium subsp. avium ATCC 25291]
Length=493

 Score =  568 bits (1463),  Expect = 1e-159, Method: Compositional matrix adjust.
 Identities = 331/488 (68%), Positives = 387/488 (80%), Gaps = 2/488 (0%)

Query  44   TWLPSRSFIAAVIAIGGMQLLATMDSTVAIVALPKIQNELSLSDAGRSWVITAYVLTFGG  103
            T L SR F+A ++AIGGMQL+  MD  VA+ ALPKIQNE+ LSDA RSWVITAY+LTFGG
Sbjct  7    TRLWSRQFVAVIVAIGGMQLMVAMDGPVAVFALPKIQNEMGLSDAARSWVITAYMLTFGG  66

Query  104  LMLLGGRLGDTIGRKRT-FIVGVALFTISSVLCAVAWDEATLVIARLSQGVGSAIASPTG  162
            LMLLGGRLGDTIGRKR  F+VGVALFT +S LC +AW   TL+ ARL  G  +AI +PT 
Sbjct  67   LMLLGGRLGDTIGRKRAAFLVGVALFTFASGLCGIAWAGGTLIAARLLHGAAAAIIAPTN  126

Query  163  LALVATTFPKGPARNAATAVFAAMTAIGSVMGLVVGGALTEVSWRWAFLVNVPIGLVMIY  222
            LAL+ATTFP+G ARNAATAVF AMT +G V+GLVVGGALT+VSWR AFLVNVPIGL +IY
Sbjct  127  LALIATTFPRGSARNAATAVFGAMTGLGGVLGLVVGGALTDVSWRLAFLVNVPIGLAVIY  186

Query  223  LARTALRETNKERMKLDATGAILATLACTAAVFAFSIGPEKGWMSGITIGSGLVALAAAV  282
            L     +ET  ER+KLD TGA+LAT+  TAAVF  S+GPE GW S ITIGSG+VALAA V
Sbjct  187  LVLITRQETQTERIKLDVTGAVLATVTGTAAVFGISMGPEAGWRSPITIGSGVVALAAFV  246

Query  283  AFVIVERTAENPVVPFHLFRDRNRLVTFSAILLAGGVMFSLTVCIGLYVQDILGYSALRA  342
            AFV+VERTAENP+VPF+LF DRNRL  F+A+ LAGGV F+LTV +GLYVQ ++GYS LRA
Sbjct  247  AFVVVERTAENPIVPFNLFLDRNRLAAFAAMFLAGGVFFTLTVLVGLYVQTMMGYSPLRA  306

Query  343  GVGFIPFVIAMGIGLGVSSQLVSRFSPRVLTIGGGYLLFGAMLYGSFFMHRGVPYFPNLV  402
            GV FIPF +AM IG+GV+S+LV+ F PRV+ I  G L+ GA LYGS F +RG+PYFPNLV
Sbjct  307  GVAFIPFGLAMAIGVGVASKLVTWFPPRVVVIASGGLILGATLYGSTF-NRGMPYFPNLV  365

Query  403  MPIVVGGIGIGMAVVPLTLSAIAGVGFDQIGPVSAIALMLQSLGGPLVLAVIQAVITSRT  462
            +P++V  IGIG   V LTLS IA V  D+IGP SAIA+MLQ+LGGPLVL V+Q  ITS  
Sbjct  366  VPLIVCAIGIGAVFVTLTLSVIASVDVDRIGPTSAIAVMLQTLGGPLVLVVVQVAITSHA  425

Query  463  LYLGGTTGPVKFMNDVQLAALDHAYTYGLLWVAGAAIIVGGMALFIGYTPQQVAHAQEVK  522
            L LGGT GPVK MN  QL ALD  YTYGLLW+AG   ++GG+ L IGYT  QVA AQEVK
Sbjct  426  LRLGGTLGPVKSMNAAQLHALDRGYTYGLLWLAGVVALLGGVTLLIGYTAAQVARAQEVK  485

Query  523  EAIDAGEL  530
            +A+DAGEL
Sbjct  486  KAVDAGEL  493


>gi|289448508|ref|ZP_06438252.1| membrane efflux protein efpA [Mycobacterium tuberculosis CPHL_A]
 gi|289421466|gb|EFD18667.1| membrane efflux protein efpA [Mycobacterium tuberculosis CPHL_A]
Length=286

 Score =  560 bits (1444),  Expect = 2e-157, Method: Compositional matrix adjust.
 Identities = 285/286 (99%), Positives = 286/286 (100%), Gaps = 0/286 (0%)

Query  245  LATLACTAAVFAFSIGPEKGWMSGITIGSGLVALAAAVAFVIVERTAENPVVPFHLFRDR  304
            +ATLACTAAVFAFSIGPEKGWMSGITIGSGLVALAAAVAFVIVERTAENPVVPFHLFRDR
Sbjct  1    MATLACTAAVFAFSIGPEKGWMSGITIGSGLVALAAAVAFVIVERTAENPVVPFHLFRDR  60

Query  305  NRLVTFSAILLAGGVMFSLTVCIGLYVQDILGYSALRAGVGFIPFVIAMGIGLGVSSQLV  364
            NRLVTFSAILLAGGVMFSLTVCIGLYVQDILGYSALRAGVGFIPFVIAMGIGLGVSSQLV
Sbjct  61   NRLVTFSAILLAGGVMFSLTVCIGLYVQDILGYSALRAGVGFIPFVIAMGIGLGVSSQLV  120

Query  365  SRFSPRVLTIGGGYLLFGAMLYGSFFMHRGVPYFPNLVMPIVVGGIGIGMAVVPLTLSAI  424
            SRFSPRVLTIGGGYLLFGAMLYGSFFMHRGVPYFPNLVMPIVVGGIGIGMAVVPLTLSAI
Sbjct  121  SRFSPRVLTIGGGYLLFGAMLYGSFFMHRGVPYFPNLVMPIVVGGIGIGMAVVPLTLSAI  180

Query  425  AGVGFDQIGPVSAIALMLQSLGGPLVLAVIQAVITSRTLYLGGTTGPVKFMNDVQLAALD  484
            AGVGFDQIGPVSAIALMLQSLGGPLVLAVIQAVITSRTLYLGGTTGPVKFMNDVQLAALD
Sbjct  181  AGVGFDQIGPVSAIALMLQSLGGPLVLAVIQAVITSRTLYLGGTTGPVKFMNDVQLAALD  240

Query  485  HAYTYGLLWVAGAAIIVGGMALFIGYTPQQVAHAQEVKEAIDAGEL  530
            HAYTYGLLWVAGAAIIVGGMALFIGYTPQQVAHAQEVKEAIDAGEL
Sbjct  241  HAYTYGLLWVAGAAIIVGGMALFIGYTPQQVAHAQEVKEAIDAGEL  286


>gi|169630224|ref|YP_001703873.1| putative transmembrane efflux protein [Mycobacterium abscessus 
ATCC 19977]
 gi|169242191|emb|CAM63219.1| Putative transmembrane efflux protein [Mycobacterium abscessus]
Length=505

 Score =  559 bits (1441),  Expect = 4e-157, Method: Compositional matrix adjust.
 Identities = 311/493 (64%), Positives = 385/493 (79%), Gaps = 1/493 (0%)

Query  36   ERPSRYYPTWLPSRSFIAAVIAIGGMQLLATMDSTVAIVALPKIQNELSLSDAGRSWVIT  95
            E+ ++    +LPSR ++ AVIAI GMQ LATMD T+A+V LPKIQ EL L+DA RSWVIT
Sbjct  7    EQLTQKAREFLPSRHYLYAVIAIAGMQFLATMDGTIAVVTLPKIQAELHLNDATRSWVIT  66

Query  96   AYVLTFGGLMLLGGRLGDTIGRKRTFIVGVALFTISSVLCAVAWDEATLVIARLSQGVGS  155
            AY+L+FGGLMLLGGRLGDT GRKR FI G+ LFT++S+   +A ++  L I RL QGVG+
Sbjct  67   AYMLSFGGLMLLGGRLGDTFGRKRVFIGGITLFTLASIGVGLAQEDIGLAIFRLIQGVGA  126

Query  156  AIASPTGLALVATTFPKGPARNAATAVFAAMTAIGSVMGLVVGGALTEVSWRWAFLVNVP  215
            A+ASPT LAL+ATTFPKGP R AA  VF AMT +GS+ GL+VGGAL EVSWR AFL+NVP
Sbjct  127  AVASPTALALIATTFPKGPLRTAAVGVFGAMTGVGSIAGLIVGGALAEVSWRLAFLINVP  186

Query  216  IGLVMIYLARTALRETNKERMKLDATGAILATLACTAAVFAFSIGPEKGWMSGITIGSGL  275
             G +MIYLA  +L ET +E MKLD  G++LATL CTAAVF F+ GP++GW S  TI S +
Sbjct  187  AGALMIYLAVRSLTETEREPMKLDVAGSVLATLGCTAAVFGFTQGPDRGWDSPYTIVSLI  246

Query  276  VALAAAVAFVIVERTAENPVVPFHLFRDRNRLVTFSAILLAGGVMFSLTVCIGLYVQDIL  335
             A A  +AF+ VERTAENPV+PF LF DRNR+ TF+AI +AGGV+F+LT+ IGLY+QD++
Sbjct  247  AAAALLIAFLFVERTAENPVLPFSLFTDRNRVATFAAIFMAGGVLFTLTITIGLYMQDLM  306

Query  336  GYSALRAGVGFIPFVIAMGIGLGVSSQLVSRFSPRVLTIGGGYLLFGAMLYGSFFMHRGV  395
             YS LR G+  IPFV+ MGIGLG+SSQLV+R +PRVL + GG ++FGAMLYGS  + R +
Sbjct  307  KYSPLRTGIAAIPFVVGMGIGLGLSSQLVTRLAPRVLILCGGVVVFGAMLYGS-TIDRTI  365

Query  396  PYFPNLVMPIVVGGIGIGMAVVPLTLSAIAGVGFDQIGPVSAIALMLQSLGGPLVLAVIQ  455
             YFP+    I VGGIGIG  VVP+ LSAI GV  D+IGP+SAI+LMLQ+LGGP+VL +IQ
Sbjct  366  AYFPDFATAIFVGGIGIGTIVVPVILSAITGVDADRIGPLSAISLMLQNLGGPIVLVIIQ  425

Query  456  AVITSRTLYLGGTTGPVKFMNDVQLAALDHAYTYGLLWVAGAAIIVGGMALFIGYTPQQV  515
            A+ITSRTLYLGG TGPV+ MN  QL ALDH YTYG+LW+AG A++VG  ALFI Y+   +
Sbjct  426  AIITSRTLYLGGATGPVQNMNRDQLHALDHGYTYGMLWIAGTAVLVGVAALFITYSAADI  485

Query  516  AHAQEVKEAIDAG  528
            AHAQ+ + A D G
Sbjct  486  AHAQKAQAAHDQG  498


>gi|120403298|ref|YP_953127.1| major facilitator superfamily transporter [Mycobacterium vanbaalenii 
PYR-1]
 gi|119956116|gb|ABM13121.1| major facilitator superfamily MFS_1 [Mycobacterium vanbaalenii 
PYR-1]
Length=508

 Score =  517 bits (1332),  Expect = 2e-144, Method: Compositional matrix adjust.
 Identities = 284/492 (58%), Positives = 372/492 (76%), Gaps = 1/492 (0%)

Query  39   SRYYPTWLPSRSFIAAVIAIGGMQLLATMDSTVAIVALPKIQNELSLSDAGRSWVITAYV  98
            S +  T L       A++AI GMQL++T+D T+ IVALP++Q EL+LSDAG+SWVITAYV
Sbjct  6    SEHATTPLSKSVLGIAIVAITGMQLMSTLDGTIVIVALPRMQAELNLSDAGKSWVITAYV  65

Query  99   LTFGGLMLLGGRLGDTIGRKRTFIVGVALFTISSVLCAVAWDEATLVIARLSQGVGSAIA  158
            L FGGL+LLGGR+GD +G KR F+ GV LFTI+S++C +A +E TLV AR  QG G+A+A
Sbjct  66   LAFGGLLLLGGRIGDAVGHKRAFLSGVGLFTIASLVCGLATEEITLVAARAFQGAGAAVA  125

Query  159  SPTGLALVATTFPKGPARNAATAVFAAMTAIGSVMGLVVGGALTEVSWRWAFLVNVPIGL  218
            +PTGLAL+ATT+  G ARN A AV AAM A GSV+GLV+GGALT VSWR AFL+NVPIG+
Sbjct  126  APTGLALIATTYAVGHARNRALAVSAAMLATGSVLGLVLGGALTVVSWRLAFLINVPIGI  185

Query  219  VMIYLARTALRETNKERMKLDATGAILATLACTAAVFAFSIGPEKGWMSGITIGSGLVAL  278
             +I +A   L ET+ ER+KLD TGA+LATLACT+AV  F+ GP +GW     IG+ + + 
Sbjct  186  AIIAIAVFRLAETHHERLKLDVTGALLATLACTSAVLFFTQGPSRGWADPFVIGAAVASA  245

Query  279  AAAVAFVIVERTAENPVVPFHLFRDRNRLVTFSAILLAGGVMFSLTVCIGLYVQDILGYS  338
               VAF +VER+A++P+VP  +F +RNR+ TF ++ LAGGVM S TV IGLYVQD++GYS
Sbjct  246  LLFVAFFVVERSADHPIVPLTVFDNRNRVATFLSLFLAGGVMLSATVMIGLYVQDVMGYS  305

Query  339  ALRAGVGFIPFVIAMGIGLGVSSQLVSRFSPRVLTIGGGYLLFGAMLYGSFFMHRGVPYF  398
            AL+AG+ FIPF +A+G+G  V++++    +PR + +G G L+  AMLYGS  + RG+PY 
Sbjct  306  ALQAGMAFIPFALALGVGTVVAARVAPYLAPRWIILGAGLLVPCAMLYGS-TLDRGIPYV  364

Query  399  PNLVMPIVVGGIGIGMAVVPLTLSAIAGVGFDQIGPVSAIALMLQSLGGPLVLAVIQAVI  458
            P+L+ P+VVGG GIG+  V L L AIA VG  +IGPVS+I LM+Q+LGGP+VL VIQAV 
Sbjct  365  PDLIAPLVVGGFGIGVISVILPLCAIADVGAREIGPVSSITLMVQNLGGPVVLVVIQAVQ  424

Query  459  TSRTLYLGGTTGPVKFMNDVQLAALDHAYTYGLLWVAGAAIIVGGMALFIGYTPQQVAHA  518
            TSRTLYLGGTTGPV  M   QL ALD  YTY LLWVA  +++VG  ALFIG++ +Q+A A
Sbjct  425  TSRTLYLGGTTGPVAAMTPAQLDALDAGYTYSLLWVAAVSVLVGAAALFIGFSARQIAVA  484

Query  519  QEVKEAIDAGEL  530
            +  ++A++ GEL
Sbjct  485  KYNRDAVETGEL  496


>gi|226366063|ref|YP_002783846.1| MFS transporter [Rhodococcus opacus B4]
 gi|226244553|dbj|BAH54901.1| putative MFS transporter [Rhodococcus opacus B4]
Length=503

 Score =  442 bits (1136),  Expect = 9e-122, Method: Compositional matrix adjust.
 Identities = 256/482 (54%), Positives = 334/482 (70%), Gaps = 2/482 (0%)

Query  31   EETASERPSRYYPTWLPSRSFIAAVIAIGGMQLLATMDSTVAIVALPKIQNELSLSDAGR  90
            E T++ + S   PT   +R    A++ + G+Q++  +D TVA +AL  +Q +L LSD+GR
Sbjct  8    ETTSASKKSAVIPTA-ATRVMGLAIVVLSGLQMMVVLDGTVANLALAPLQADLGLSDSGR  66

Query  91   SWVITAYVLTFGGLMLLGGRLGDTIGRKRTFIVGVALFTISSVLCAVAWDEATLVIARLS  150
            +WV+T+Y L FGGLMLLGGRLGD  GRK+ F+ GVALFT++S+LC +A  E  L+ AR  
Sbjct  67   NWVLTSYALAFGGLMLLGGRLGDAFGRKKMFVGGVALFTVASLLCGLAVGEFMLIAARFL  126

Query  151  QGVGSAIASPTGLALVATTFPKGPARNAATAVFAAMTAIGSVMGLVVGGALTEVSWRWAF  210
            QGVG+A+ASPT LALVATTF  GPARN A A+FAAMT IGS+ GL++GGALTEVSWR  F
Sbjct  127  QGVGAAVASPTALALVATTFAAGPARNQAIAIFAAMTGIGSIAGLIIGGALTEVSWRLIF  186

Query  211  LVNVPIGLVMIYLARTALRETNKERMKLDATGAILATLACTAAVFAFSIGPEKGWMSGIT  270
            L+NVPIG+V++  A  AL+ET  ER+ LD  GA+LAT+A T  VFA + GPE GW S   
Sbjct  187  LINVPIGVVIVGCAVVALKETAGERLALDVPGAVLATVAATGVVFALTEGPELGWASPYV  246

Query  271  IGSGLVALAAAVAFVIVERTAENPVVPFHLFRDRNRLVTFSAILLAGGVMFSLTVCIGLY  330
            IG+ +  L    AF+ VERTA+NP++PF LF D+NR+ T  AI  AG VMF++   + L+
Sbjct  247  IGALVAGLLLFGAFLYVERTADNPLLPFSLFHDKNRVATLVAIFFAGAVMFTVAAFVALF  306

Query  331  VQDILGYSALRAGVGFIPFVIAMGIGLGVSSQLVSRFSPRVLTIGGGYLLFGAMLYGSFF  390
            VQDILGYS L AG+ FIPF   +G    V+S+L  R  PR L + G  ++   +LYGS  
Sbjct  307  VQDILGYSPLEAGLAFIPFAFGLGSAAAVASKLAVRIQPRWLVVAGATIMVVGLLYGS-T  365

Query  391  MHRGVPYFPNLVMPIVVGGIGIGMAVVPLTLSAIAGVGFDQIGPVSAIALMLQSLGGPLV  450
            +     Y  NL +P++  G G+G+AVVPL L AIAGV   +IGP++AIA + Q+LGGPL 
Sbjct  366  LDSSATYLANLFVPVIGIGFGVGLAVVPLPLCAIAGVSETEIGPLAAIAQVAQTLGGPLA  425

Query  451  LAVIQAVITSRTLYLGGTTGPVKFMNDVQLAALDHAYTYGLLWVAGAAIIVGGMALFIGY  510
            LAVI A+ TSRTL LGG +G V  MN  QL AL + YT+ L+  AG A+I G  ALFI +
Sbjct  426  LAVIGAMATSRTLSLGGISGKVADMNPAQLEALGNGYTFALVGSAGCALIAGFAALFIRF  485

Query  511  TP  512
            TP
Sbjct  486  TP  487


>gi|111023577|ref|YP_706549.1| major facilitator superfamily multidrug transporter [Rhodococcus 
jostii RHA1]
 gi|110823107|gb|ABG98391.1| multidrug transporter, MFS superfamily protein [Rhodococcus jostii 
RHA1]
Length=507

 Score =  439 bits (1130),  Expect = 4e-121, Method: Compositional matrix adjust.
 Identities = 253/459 (56%), Positives = 325/459 (71%), Gaps = 1/459 (0%)

Query  54   AVIAIGGMQLLATMDSTVAIVALPKIQNELSLSDAGRSWVITAYVLTFGGLMLLGGRLGD  113
            A+I + G+Q++  +D TVA +AL  +Q +L LSD+GR+WV+T+Y L FGGLMLLGGRLGD
Sbjct  34   AIIVLSGLQMMVVLDGTVANLALAPLQADLGLSDSGRNWVLTSYALAFGGLMLLGGRLGD  93

Query  114  TIGRKRTFIVGVALFTISSVLCAVAWDEATLVIARLSQGVGSAIASPTGLALVATTFPKG  173
              GRK+ F+ GVALFT++S+LC +A  E  L+ AR  QGVG+A+ASPT LALVATTF  G
Sbjct  94   AFGRKKMFVGGVALFTVASLLCGLAVGEFMLIAARFLQGVGAAVASPTALALVATTFAAG  153

Query  174  PARNAATAVFAAMTAIGSVMGLVVGGALTEVSWRWAFLVNVPIGLVMIYLARTALRETNK  233
            PARN A A+FAAMT IGS+ GL++GGALTEVSWR  FL+NVPIG+V++  A  AL+ET  
Sbjct  154  PARNQAIAIFAAMTGIGSIAGLIIGGALTEVSWRLIFLINVPIGVVIVGCAFVALKETAG  213

Query  234  ERMKLDATGAILATLACTAAVFAFSIGPEKGWMSGITIGSGLVALAAAVAFVIVERTAEN  293
            ER+ LD  GA+LAT+A T  VFA + GPE GW S   IG+ +  L    AF+ VERTA+N
Sbjct  214  ERLALDVPGAVLATVAATGVVFALTEGPELGWGSPYVIGALVAGLLLFCAFLYVERTADN  273

Query  294  PVVPFHLFRDRNRLVTFSAILLAGGVMFSLTVCIGLYVQDILGYSALRAGVGFIPFVIAM  353
            P++PF LFRD+NR+ T  AI  AG VMF++   + L+VQDILGYS L AG+ FIPF   +
Sbjct  274  PLLPFSLFRDKNRVATLVAIFFAGAVMFTVAAFVALFVQDILGYSPLEAGLAFIPFAFGL  333

Query  354  GIGLGVSSQLVSRFSPRVLTIGGGYLLFGAMLYGSFFMHRGVPYFPNLVMPIVVGGIGIG  413
            G    V+S+L  R  PR L I G  ++   +LYGS  +     Y  NL +P++  G G+G
Sbjct  334  GGAAAVASKLAVRIQPRWLVIAGAAIMVVGLLYGS-TLDSSATYLGNLFVPVIGIGFGVG  392

Query  414  MAVVPLTLSAIAGVGFDQIGPVSAIALMLQSLGGPLVLAVIQAVITSRTLYLGGTTGPVK  473
            +AVVPL L AIAGV   +IGP++AIA + Q+LGGPL LAVI A+ TSRTL LGG +G V 
Sbjct  393  LAVVPLPLCAIAGVSETEIGPLAAIAQVAQTLGGPLALAVIGAMATSRTLSLGGISGKVA  452

Query  474  FMNDVQLAALDHAYTYGLLWVAGAAIIVGGMALFIGYTP  512
             MN  QL AL + YT+ L+  AG A+I G  ALFI +TP
Sbjct  453  DMNPTQLEALGNGYTFALVGSAGCALIAGLAALFIRFTP  491


>gi|226306098|ref|YP_002766058.1| drug resistance efflux protein [Rhodococcus erythropolis PR4]
 gi|226185215|dbj|BAH33319.1| putative drug resistance efflux protein [Rhodococcus erythropolis 
PR4]
Length=498

 Score =  432 bits (1112),  Expect = 6e-119, Method: Compositional matrix adjust.
 Identities = 254/484 (53%), Positives = 331/484 (69%), Gaps = 3/484 (0%)

Query  30   SEETASERPSRYYPTWLPSRSFIAAVIAIGGMQLLATMDSTVAIVALPKIQNELSLSDAG  89
            S+   SE  S   P  + +R    A+I + G+Q++  +D TVA +AL  +Q +L LSD+G
Sbjct  2    SDSPTSETASANAP--VATRVIGLAIIVLSGLQMMVVLDGTVANLALAPLQADLGLSDSG  59

Query  90   RSWVITAYVLTFGGLMLLGGRLGDTIGRKRTFIVGVALFTISSVLCAVAWDEATLVIARL  149
            R+WV+T+Y L FGGLMLLGGRLGD  GRK+ FI GV+LFT++S+LC +A +E  L+ AR 
Sbjct  60   RNWVLTSYALAFGGLMLLGGRLGDAYGRKKMFIAGVSLFTVASLLCGLALNEGMLIAARA  119

Query  150  SQGVGSAIASPTGLALVATTFPKGPARNAATAVFAAMTAIGSVMGLVVGGALTEVSWRWA  209
             QGVG+A+ASPT  ALVATTF  GPARN A A+FAAMT +GS+ GL++GGALTEVSWR  
Sbjct  120  LQGVGAAVASPTAFALVATTFAAGPARNQAIAIFAAMTGVGSIAGLIIGGALTEVSWRLI  179

Query  210  FLVNVPIGLVMIYLARTALRETNKERMKLDATGAILATLACTAAVFAFSIGPEKGWMSGI  269
            FL+NVPIG+ ++ +A  ALRETN+ R+ LD  GAILATL CT  VFA + GPE GW S  
Sbjct  180  FLINVPIGIALVGMAFRALRETNQTRLALDVPGAILATLGCTGVVFALTEGPEMGWGSIA  239

Query  270  TIGSGLVALAAAVAFVIVERTAENPVVPFHLFRDRNRLVTFSAILLAGGVMFSLTVCIGL  329
             IG+    L A  AF+ VERTA+NP++PF LF DRNR+ TF AI   GG MFS+T  + L
Sbjct  240  VIGALAAGLVALAAFLFVERTADNPLLPFSLFADRNRVATFLAIFFVGGAMFSMTAFVAL  299

Query  330  YVQDILGYSALRAGVGFIPFVIAMGIGLGVSSQLVSRFSPRVLTIGGGYLLFGAMLYGSF  389
            +VQDI+ YS LRAG+ FIPF   +G    V+S+L  +  PR L + G  ++   +LYGS 
Sbjct  300  FVQDIMQYSPLRAGIAFIPFAFGLGAAASVASKLAVKVQPRWLVLTGVVIMIVGLLYGS-  358

Query  390  FMHRGVPYFPNLVMPIVVGGIGIGMAVVPLTLSAIAGVGFDQIGPVSAIALMLQSLGGPL  449
             +     Y  NL +P++  G GIG+A+VPL L AIAGV   +IGP++AIA + Q+LGGPL
Sbjct  359  TLDSDSTYLANLFVPVIGIGFGIGLAMVPLPLCAIAGVPETEIGPLTAIAQVAQTLGGPL  418

Query  450  VLAVIQAVITSRTLYLGGTTGPVKFMNDVQLAALDHAYTYGLLWVAGAAIIVGGMALFIG  509
             L+VI A+ TS+TL LGGT+G    MN  QL AL   YT+ L+  A  A+  G  AL I 
Sbjct  419  ALSVIGAMATSKTLSLGGTSGKAADMNPAQLIALGEGYTFALVGCAVCAVFAGIAALCIR  478

Query  510  YTPQ  513
            +TP 
Sbjct  479  FTPS  482


>gi|229491343|ref|ZP_04385167.1| multidrug transporter, MFS family [Rhodococcus erythropolis SK121]
 gi|229321628|gb|EEN87425.1| multidrug transporter, MFS family [Rhodococcus erythropolis SK121]
Length=498

 Score =  432 bits (1110),  Expect = 1e-118, Method: Compositional matrix adjust.
 Identities = 253/484 (53%), Positives = 331/484 (69%), Gaps = 3/484 (0%)

Query  30   SEETASERPSRYYPTWLPSRSFIAAVIAIGGMQLLATMDSTVAIVALPKIQNELSLSDAG  89
            S+   SE  S   P  + +R    A+I + G+Q++  +D TVA +AL  +Q +L LSD+G
Sbjct  2    SDSPTSETASANAP--VATRVIGLAIIVLSGLQMMVVLDGTVANLALAPLQADLGLSDSG  59

Query  90   RSWVITAYVLTFGGLMLLGGRLGDTIGRKRTFIVGVALFTISSVLCAVAWDEATLVIARL  149
            R+WV+T+Y L FGGLMLLGGRLGD  GRK+ FI GV+LFT++S+LC +A +E  L+ AR 
Sbjct  60   RNWVLTSYALAFGGLMLLGGRLGDAFGRKKMFIAGVSLFTVASLLCGLALNEGMLIAARA  119

Query  150  SQGVGSAIASPTGLALVATTFPKGPARNAATAVFAAMTAIGSVMGLVVGGALTEVSWRWA  209
             QGVG+A+ASPT  ALVATTF  GPARN A A+FAAMT +GS+ GL++GGALTEVSWR  
Sbjct  120  LQGVGAAVASPTAFALVATTFAAGPARNQAIAIFAAMTGVGSIAGLIIGGALTEVSWRLI  179

Query  210  FLVNVPIGLVMIYLARTALRETNKERMKLDATGAILATLACTAAVFAFSIGPEKGWMSGI  269
            FL+NVPIG+ ++ +A  ALRETN+ R+ LD  GAILATL CT  VFA + GPE GW S  
Sbjct  180  FLINVPIGIALVGMAFRALRETNQTRLALDVPGAILATLGCTGVVFALTEGPEMGWGSIA  239

Query  270  TIGSGLVALAAAVAFVIVERTAENPVVPFHLFRDRNRLVTFSAILLAGGVMFSLTVCIGL  329
             IG+    L A  AF+ VERTA+NP++PF LF DRNR+ TF AI   GG MFS+T  + L
Sbjct  240  VIGALAAGLVALAAFLFVERTADNPLLPFSLFADRNRVATFLAIFFVGGAMFSMTAFVAL  299

Query  330  YVQDILGYSALRAGVGFIPFVIAMGIGLGVSSQLVSRFSPRVLTIGGGYLLFGAMLYGSF  389
            +VQDI+ YS LRAG+ FIPF   +G    V+S+L  +  PR L + G  ++   +LYGS 
Sbjct  300  FVQDIMQYSPLRAGIAFIPFAFGLGAAASVASKLAVKVQPRWLVLTGVVIMIVGLLYGS-  358

Query  390  FMHRGVPYFPNLVMPIVVGGIGIGMAVVPLTLSAIAGVGFDQIGPVSAIALMLQSLGGPL  449
             +     Y  NL +P++  G GIG+A+VPL L AIAGV   +IGP++AI+ + Q+LGGPL
Sbjct  359  TLDSDSTYLANLFVPVIGIGFGIGLAMVPLPLCAIAGVPETEIGPLTAISQVAQTLGGPL  418

Query  450  VLAVIQAVITSRTLYLGGTTGPVKFMNDVQLAALDHAYTYGLLWVAGAAIIVGGMALFIG  509
             L+VI A+ TS+TL LGGT+G    MN  QL AL   YT+ L+  A  A+  G  AL I 
Sbjct  419  ALSVIGAMATSKTLSLGGTSGKAADMNPAQLIALGEGYTFALVGCAVCAVFAGIAALCIR  478

Query  510  YTPQ  513
            +TP 
Sbjct  479  FTPS  482


>gi|325673401|ref|ZP_08153092.1| efflux protein [Rhodococcus equi ATCC 33707]
 gi|325555422|gb|EGD25093.1| efflux protein [Rhodococcus equi ATCC 33707]
Length=493

 Score =  404 bits (1039),  Expect = 2e-110, Method: Compositional matrix adjust.
 Identities = 263/483 (55%), Positives = 337/483 (70%), Gaps = 10/483 (2%)

Query  35   SERPSRYYPTWLPSRSFIAAVIAIGGMQLLATMDSTVAIVALPKIQNELSLSDAGRSWVI  94
            S+  +  YP  + +R+F  A++ + GMQL+  +D TVA +AL KIQ +L LSD+GR+WVI
Sbjct  2    SDSTAVKYP--VTTRAFGLAIVVLSGMQLMMVLDGTVASLALAKIQEDLGLSDSGRNWVI  59

Query  95   TAYVLTFGGLMLLGGRLGDTIGRKRTFIVGVALFTISSVLCAVAWDEATLVIARLSQGVG  154
            T+Y LTFGGLMLLGGRLGD  GRKR FI GVALFT++S+LC +A +EATLV AR  QGVG
Sbjct  60   TSYALTFGGLMLLGGRLGDAFGRKRVFIGGVALFTVTSLLCGLATNEATLVAARALQGVG  119

Query  155  SAIASPTGLALVATTFPKGPARNAATAVFAAMTAIGSVMGLVVGGALTEVSWRWAFLVNV  214
            +AIASPT LALVATTF  GP RN A A+FAAMT +GSV+GL+VGGALTEVSWRW FL+NV
Sbjct  120  AAIASPTALALVATTFAPGPVRNQAIAIFAAMTGVGSVLGLIVGGALTEVSWRWIFLINV  179

Query  215  PIGLVMIYLARTALRETNKERMKLDATGAILATLACTAAVFAFSIGPEKGWMSGIT-IG-  272
            PIGLV++ LA  AL ET  ER+KLD  GAILATL CT  V+ F+ GPE GW S +  IG 
Sbjct  180  PIGLVILLLAFRALEETGAERLKLDVPGAILATLGCTGVVYGFTEGPEMGWGSPLVLIGL  239

Query  273  -SGLVALAAAVAFVIVERTAENPVVPFHLFRDRNRLVTFSAILLAGGVMFSLTVCIGLYV  331
              G V L    AF+ VER AENP++PF LFR+R+R+ TF ++ L G VMFSL   + L+V
Sbjct  240  VGGFVLLG---AFLAVERRAENPLLPFTLFRNRSRVATFISLALVGMVMFSLAPFVALFV  296

Query  332  QDILGYSALRAGVGFIPFVIAMGIGLGVSSQLVSRFSPRVLTIGGGYLLFGAMLYGSFFM  391
            QD+L Y+ LRAG+ F+PF   +G    V+S++  +  PR L + G  + F  ++YGS  +
Sbjct  297  QDVLAYTPLRAGLAFVPFAFGLGAAAFVASKIAVKVQPRWLVVAGTLITFVGLMYGS-TL  355

Query  392  HRGVPYFPNLVMPIVVGGIGIGMAVVPLTLSAIAGVGFDQIGPVSAIALMLQSLGGPLVL  451
                 Y  NL + +V  G G+G+AVVPL L AIAGVG  +IGP++AIA + Q+L GP+ L
Sbjct  356  DASATYVGNLFVLVVGVGFGVGLAVVPLPLCAIAGVGPSEIGPLAAIAQVAQTLFGPVGL  415

Query  452  AVIQAVITSRTLYLGGTTG-PVKFMNDVQLAALDHAYTYGLLWVAGAAIIVGGMALFIGY  510
            A++ A+ TSRTL  GG +G P   M   QL AL   YT+ LL  A  A +    ALFI +
Sbjct  416  AIVGAMATSRTLSEGGVSGIPAADMTPAQLDALSSGYTFALLGCAILAALAALAALFIRF  475

Query  511  TPQ  513
            TP+
Sbjct  476  TPE  478


>gi|312139293|ref|YP_004006629.1| mfs transporter [Rhodococcus equi 103S]
 gi|311888632|emb|CBH47944.1| putative MFS transporter [Rhodococcus equi 103S]
Length=487

 Score =  404 bits (1037),  Expect = 2e-110, Method: Compositional matrix adjust.
 Identities = 263/476 (56%), Positives = 334/476 (71%), Gaps = 10/476 (2%)

Query  42   YPTWLPSRSFIAAVIAIGGMQLLATMDSTVAIVALPKIQNELSLSDAGRSWVITAYVLTF  101
            YP  + +R+F  A++ + GMQL+  +D TVA +AL KIQ +L LSD+GR+WVIT+Y LTF
Sbjct  3    YP--VTTRAFGLAIVVLSGMQLMMVLDGTVASLALAKIQEDLGLSDSGRNWVITSYALTF  60

Query  102  GGLMLLGGRLGDTIGRKRTFIVGVALFTISSVLCAVAWDEATLVIARLSQGVGSAIASPT  161
            GGLMLLGGRLGD  GRKR FI GVALFT++S+LC +A +EATLV AR  QGVG+AIASPT
Sbjct  61   GGLMLLGGRLGDAFGRKRVFIGGVALFTVTSLLCGLATNEATLVAARALQGVGAAIASPT  120

Query  162  GLALVATTFPKGPARNAATAVFAAMTAIGSVMGLVVGGALTEVSWRWAFLVNVPIGLVMI  221
             LALVATTF  GP RN A A+FAAMT +GSV+GL+VGGALTEVSWRW FL+NVPIGLV++
Sbjct  121  ALALVATTFAPGPVRNQAIAIFAAMTGVGSVLGLIVGGALTEVSWRWIFLINVPIGLVIL  180

Query  222  YLARTALRETNKERMKLDATGAILATLACTAAVFAFSIGPEKGWMSGIT-IG--SGLVAL  278
             LA  AL ET  ER+KLD  GAILATL CT  VF F+ GPE GW S +  IG   G V L
Sbjct  181  LLAFRALEETGAERLKLDVPGAILATLGCTGVVFGFTEGPEMGWGSPLVLIGLVGGFVLL  240

Query  279  AAAVAFVIVERTAENPVVPFHLFRDRNRLVTFSAILLAGGVMFSLTVCIGLYVQDILGYS  338
                AF+ VER AENP++PF LFR+R+R+ TF ++ L G VMFSL   + L+VQD+L Y+
Sbjct  241  G---AFLAVERRAENPLLPFTLFRNRSRVATFISLALVGMVMFSLAPFVALFVQDVLAYT  297

Query  339  ALRAGVGFIPFVIAMGIGLGVSSQLVSRFSPRVLTIGGGYLLFGAMLYGSFFMHRGVPYF  398
             LRAG+ F+PF   +G    V+S++  +  PR L + G  + F  ++YGS  +     Y 
Sbjct  298  PLRAGLAFVPFAFGLGAAAFVASKIAVKVQPRWLVVAGTLITFVGLMYGS-TLDASATYV  356

Query  399  PNLVMPIVVGGIGIGMAVVPLTLSAIAGVGFDQIGPVSAIALMLQSLGGPLVLAVIQAVI  458
             NL + +V  G G+G+AVVPL L AIAGVG  +IGP++AIA + Q+L GP+ LA++ A+ 
Sbjct  357  GNLFVLVVGVGFGVGLAVVPLPLCAIAGVGPSEIGPLAAIAQVAQTLFGPVGLAIVGAMA  416

Query  459  TSRTLYLGGTTG-PVKFMNDVQLAALDHAYTYGLLWVAGAAIIVGGMALFIGYTPQ  513
            TSRTL  GG +G P   M   QL AL   YT+ LL  A  A +    ALFI +TP+
Sbjct  417  TSRTLSEGGVSGIPAADMTPAQLDALSSGYTFALLGCAILAALAALAALFIRFTPE  472


>gi|333919283|ref|YP_004492864.1| putative MFS transporter [Amycolicicoccus subflavus DQS3-9A1]
 gi|333481504|gb|AEF40064.1| Putative MFS transporter [Amycolicicoccus subflavus DQS3-9A1]
Length=499

 Score =  393 bits (1010),  Expect = 4e-107, Method: Compositional matrix adjust.
 Identities = 224/439 (52%), Positives = 312/439 (72%), Gaps = 1/439 (0%)

Query  54   AVIAIGGMQLLATMDSTVAIVALPKIQNELSLSDAGRSWVITAYVLTFGGLMLLGGRLGD  113
            A++ +  +QL+  +D TV  +AL ++Q++L+LSD+GR+WV+T+Y L FGGLMLLGGRLGD
Sbjct  21   AIVVLSALQLMVVLDGTVVNLALARLQDDLALSDSGRTWVVTSYALAFGGLMLLGGRLGD  80

Query  114  TIGRKRTFIVGVALFTISSVLCAVAWDEATLVIARLSQGVGSAIASPTGLALVATTFPKG  173
            T GRKR F+ GVA+FT++S++  +A  + TL+ AR+ QG G+A+ASPT  ALVATTF  G
Sbjct  81   TFGRKRMFMYGVAVFTVASLIAGLATTDITLIAARVLQGAGAAVASPTAFALVATTFAPG  140

Query  174  PARNAATAVFAAMTAIGSVMGLVVGGALTEVSWRWAFLVNVPIGLVMIYLARTALRETNK  233
            P RN A A+FA MT +GSV GL++GGALTE+SWRW FLVN+P+G  ++++ART+L E+  
Sbjct  141  PVRNQAFAIFAMMTGLGSVSGLLLGGALTEISWRWIFLVNLPVGAFILFMARTSLPESQG  200

Query  234  ERMKLDATGAILATLACTAAVFAFSIGPEKGWMSGITIGSGLVALAAAVAFVIVERTAEN  293
             R  LD  GAILAT  CTA V+    G E GW S + I + ++ +    AF+ VERTAEN
Sbjct  201  PRRSLDVPGAILATTGCTALVYGLQHGAESGWNSTLVILALVLGVLLLTAFLAVERTAEN  260

Query  294  PVVPFHLFRDRNRLVTFSAILLAGGVMFSLTVCIGLYVQDILGYSALRAGVGFIPFVIAM  353
            P++PF LFR+R+R+ TF AI+LAG +   + V + L+VQD+L +S L AG+ F+PF  A+
Sbjct  261  PLLPFVLFRNRDRVATFVAIMLAGAITMCMAVFVALFVQDVLLFSPLEAGLSFVPFAFAL  320

Query  354  GIGLGVSSQLVSRFSPRVLTIGGGYLLFGAMLYGSFFMHRGVPYFPNLVMPIVVGGIGIG  413
            G+   V+S+L  R  PR L   GG L+   + Y S  M +   YFP+L +PIV+ G G+G
Sbjct  321  GLTAQVASKLAMRIQPRWLVATGGLLVAAGLAYAS-TMDQNSTYFPDLFVPIVMVGAGVG  379

Query  414  MAVVPLTLSAIAGVGFDQIGPVSAIALMLQSLGGPLVLAVIQAVITSRTLYLGGTTGPVK  473
            M+VVPLTL A+AGV   +IGP++AIAL+ Q+LGG L L  + A+ T+RTL LGG+TGP  
Sbjct  380  MSVVPLTLCAVAGVRSSEIGPLTAIALVAQTLGGALGLGAVGALATARTLSLGGSTGPAS  439

Query  474  FMNDVQLAALDHAYTYGLL  492
             M++ QL AL   Y + L+
Sbjct  440  AMDEAQLVALGEGYLFALV  458


>gi|262202078|ref|YP_003273286.1| EmrB/QacA subfamily drug resistance transporter [Gordonia bronchialis 
DSM 43247]
 gi|262085425|gb|ACY21393.1| drug resistance transporter, EmrB/QacA subfamily [Gordonia bronchialis 
DSM 43247]
Length=520

 Score =  382 bits (980),  Expect = 1e-103, Method: Compositional matrix adjust.
 Identities = 245/508 (49%), Positives = 338/508 (67%), Gaps = 8/508 (1%)

Query  26   RPPRSEETASERPSRYY-PTWLPS--RSFIAAVIAIGGMQLLATMDSTVAIVALPKIQNE  82
            RP  S   A+    +++ PT  P   + F  A++ + GMQLL  +D TVA +ALP+I+  
Sbjct  7    RPVASSVMATSGTWQHHAPTAGPEYRKVFGPAILVLSGMQLLMVLDGTVAALALPRIREA  66

Query  83   LSLSDAGRSWVITAYVLTFGGLMLLGGRLGDTIGRKRTFIVGVALFTISSVLCAVAWDEA  142
            LSLS+AG +W+I++YVL FGGLMLLGGRLGDT GRKR FIVGV  FT++S+LC VA +EA
Sbjct  67   LSLSEAGANWIISSYVLAFGGLMLLGGRLGDTFGRKRMFIVGVWAFTLTSLLCGVAQNEA  126

Query  143  TLVIARLSQGVGSAIASPTGLALVATTFPKGPARNAATAVFAAMTAIGSVMGLVVGGALT  202
             L++ R  QG  +AIA+PT +ALVATTF  G  R+ A A++AAMT +GSV GL++GG LT
Sbjct  127  MLIVGRALQGASAAIAAPTAMALVATTFAPGKPRSQAFAIYAAMTGVGSVAGLILGGVLT  186

Query  203  EVSWRWAFLVNVPIGLVMIYLARTALRETNKERMKLDATGAILATLACTAAVFAFSIGPE  262
            EVSWR  FL+NVPIG+++ + A   LRE   ER+ LD  GA+L TL CT  V A + GP 
Sbjct  187  EVSWRLVFLINVPIGIIVAFGAMLVLREAQGERLSLDIPGAVLGTLGCTLLVLAVNEGP-  245

Query  263  KGWMSGITIGSGLVALAAAVAFVIVERTAENPVVPFHLFRDRNRLVTFSAILLAGGVMFS  322
             GW   I +GS ++   A +AFV+VER A NP++PF LF + +R+    AILLA  +M  
Sbjct  246  NGWGRPIVVGSFVLGALALIAFVVVERRAANPILPFSLFDNTSRVAALVAILLASMIMMC  305

Query  323  LTVCIGLYVQDILGYSALRAGVGFIPFVIAMGIGLGVSSQLVSRFSPRVLTIGGGYLLFG  382
            + V I LY+Q IL YS +++G+  +PF   +GI   ++S++     PR L + GG ++  
Sbjct  306  MAVFISLYLQGILKYSPIQSGLAVVPFAFGLGIAAAIASKVSLMIQPRWLVLTGGAVILA  365

Query  383  AMLYGSFFMHRGVPYFPNLVMPIVVGGIGIGMAVVPLTLSAIAGVGFDQIGPVSAIALML  442
              LY +        YFPN+ +P+VV G G+G+AV+PLTLS +AGVG ++IGP++A+A + 
Sbjct  366  GCLYAASIATDMPGYFPNIALPVVVIGFGVGLAVIPLTLSVVAGVGPNEIGPLTALAQVA  425

Query  443  QSLGGPLVLAVIQAVITSRTLYLGGTTGPVKFMNDVQLAALDHAYTYGLLWVAGAAIIV-  501
            Q+LGG + L  + A++TSR L  GGTTGPV+ MN  QLAA   A  YGL +   A I V 
Sbjct  426  QNLGGAIGLVAVGAMVTSRALSQGGTTGPVEDMNPAQLAA--QADGYGLAFACCAGIAVL  483

Query  502  -GGMALFIGYTPQQVAHAQEVKEAIDAG  528
               + +F+ +TP+QVA  Q  +EA DAG
Sbjct  484  AAVVVMFMRFTPEQVAEGQAAQEAADAG  511


>gi|296139418|ref|YP_003646661.1| EmrB/QacA subfamily drug resistance transporter [Tsukamurella 
paurometabola DSM 20162]
 gi|296027552|gb|ADG78322.1| drug resistance transporter, EmrB/QacA subfamily [Tsukamurella 
paurometabola DSM 20162]
Length=757

 Score =  380 bits (975),  Expect = 5e-103, Method: Compositional matrix adjust.
 Identities = 218/485 (45%), Positives = 308/485 (64%), Gaps = 12/485 (2%)

Query  54   AVIAIGGMQLLATMDSTVAIVALPKIQNELSLSDAGRSWVITAYVLTFGGLMLLGGRLGD  113
            A++ + GM  LA +D TV  +A+P IQ+ + LSDA + WV  AYVLTFGG MLLGGRLGD
Sbjct  20   AIVVLSGMMFLAVLDGTVVFIAMPSIQDAMHLSDAAKIWVFGAYVLTFGGFMLLGGRLGD  79

Query  114  TIGRKRTFIVGVALFTISSVLCAVAWDEATLVIARLSQGVGSAIASPTGLALVATTFPKG  173
            T GRKR FIVGVA FT++S+L   A +E  L+ AR  QG+ +AIA PT LAL+ATTF  G
Sbjct  80   TFGRKRMFIVGVAGFTLASLLTGFASNEVWLLAARAGQGLFAAIACPTALALIATTFAPG  139

Query  174  PARNAATAVFAAMTAIGSVMGLVVGGALTEVSWRWAFLVNVPIGLVMIYLARTALRETNK  233
             ARN A A+F AM  +GSV GLV GG L  + WR  F +N+P+G+V +  A  AL E+  
Sbjct  140  KARNQAFAIFGAMAGLGSVAGLVAGGLLATIDWRLVFWINIPVGVVCVIGAIVALEESTA  199

Query  234  E-RMKLDATGAILATLACTAAVFAFSIGPEKGWMSGITIGSGLVALAAAVAFVIVERTAE  292
            E R  LD  GA LA   C A V+A ++GPE  W S     + +V + +   F+ VERTA+
Sbjct  200  ERRHSLDVKGAFLAVTGCVAGVYALTMGPEVHWQSPSVYIAAVVCVVSLAVFLQVERTAK  259

Query  293  NPVVPFHLFRDRNRLVTFSAILLAGGVMFSLTVCIGLYVQDILGYSALRAGVGFIPFVIA  352
            NP++PF LFR++NR+    AIL+ G ++ +L   + L  Q +LGY+ L +G+  +PF + 
Sbjct  260  NPILPFSLFRNKNRVAAMIAILVCGALIPTLGFYVALTFQQVLGYTPLESGLALVPFAVG  319

Query  353  MGIGLGVSSQLVSRFSPRVLTIGGGYLLFGAMLYGSFFMHRG---VPYFPNLVMPIVVGG  409
            MGI   +SSQL  +F  R L   GG ++F   LY    M R    V YFP + +P+ + G
Sbjct  320  MGISAPISSQLALKFQARWLVAIGGLIVFLPCLYVPTLMTRDPSTVSYFPYIGIPVFIIG  379

Query  410  IGIGMAVVPLTLSAIAGVGFDQIGPVSAIALMLQSLGGPLVLAVIQAVITSRTLYLGG-T  468
            +G+G+A+VPL + A+AGV   + GP+SA+  + Q+LGG + LA +Q ++TSR +  GG T
Sbjct  380  LGVGLAIVPLPICALAGVRPSETGPMSALVEVCQNLGGIIGLASVQVLVTSRIMKEGGPT  439

Query  469  TGPVKF--MNDVQLAALDHAYTYGLLWVAGAAI-IVGGMAL--FIGYTPQQVAHAQEVKE  523
            TG +    +++ Q  AL  A  YGL ++A AAI I+ G+ +  F+ +TP +VA  Q  +E
Sbjct  440  TGEISHDALSEAQRHAL--ASGYGLAFIACAAILILAGLVVVPFMRFTPDEVAEGQAAQE  497

Query  524  AIDAG  528
            +  +G
Sbjct  498  SNKSG  502


>gi|343926761|ref|ZP_08766258.1| putative major facilitator superfamily transporter [Gordonia 
alkanivorans NBRC 16433]
 gi|343763360|dbj|GAA13184.1| putative major facilitator superfamily transporter [Gordonia 
alkanivorans NBRC 16433]
Length=488

 Score =  378 bits (971),  Expect = 1e-102, Method: Compositional matrix adjust.
 Identities = 242/497 (49%), Positives = 331/497 (67%), Gaps = 12/497 (2%)

Query  32   ETASERPSRYYPTWLPSRSFIAAVIAIGGMQLLATMDSTVAIVALPKIQNELSLSDAGRS  91
            +TA  RP    P           ++ + GMQLL  +D TVA +ALP+I++ LSLS++  +
Sbjct  2    DTAQFRPVFGLP-----------ILVLSGMQLLMVLDGTVAALALPRIRDALSLSESSAN  50

Query  92   WVITAYVLTFGGLMLLGGRLGDTIGRKRTFIVGVALFTISSVLCAVAWDEATLVIARLSQ  151
            WVI++YVL FGGLMLLGGRLGDT GRKR FIVGV  FT++S+LC +AW+EA+L++ R  Q
Sbjct  51   WVISSYVLAFGGLMLLGGRLGDTFGRKRMFIVGVVAFTLTSLLCGLAWNEASLIVGRALQ  110

Query  152  GVGSAIASPTGLALVATTFPKGPARNAATAVFAAMTAIGSVMGLVVGGALTEVSWRWAFL  211
            G  +AIA+PT +ALVATTF  G  R+ A AV+AAMT +GSV GL+VGG LTEVSWR  FL
Sbjct  111  GASAAIAAPTAMALVATTFAPGKPRSQAFAVYAAMTGVGSVAGLIVGGVLTEVSWRLVFL  170

Query  212  VNVPIGLVMIYLARTALRETNKERMKLDATGAILATLACTAAVFAFSIGPEKGWMSGITI  271
            +NVPIGLV++  A  ALRE+  ER+ LD  GA+L TL CT  V   + GP  GW S + I
Sbjct  171  INVPIGLVVVIGAIIALRESQGERLPLDVPGAVLGTLGCTLLVLGVNEGP-NGWGSPVVI  229

Query  272  GSGLVALAAAVAFVIVERTAENPVVPFHLFRDRNRLVTFSAILLAGGVMFSLTVCIGLYV  331
            GS ++ + A +AFV+VER A NP++PF LF + +R+    AIL A  +M  + V I LY+
Sbjct  230  GSFVLGVLALIAFVVVERRAANPILPFSLFDNTSRVAALGAILFASMIMMCMAVFISLYL  289

Query  332  QDILGYSALRAGVGFIPFVIAMGIGLGVSSQLVSRFSPRVLTIGGGYLLFGAMLYGSFFM  391
            Q IL YS +++G+  +PF   +GI   ++S+L     PR L + GG ++     Y S   
Sbjct  290  QGILKYSPIQSGLAVVPFAFGLGIAAAIASKLSLMTQPRWLVLVGGAVILAGCFYASSIA  349

Query  392  HRGVPYFPNLVMPIVVGGIGIGMAVVPLTLSAIAGVGFDQIGPVSAIALMLQSLGGPLVL  451
                 YFP++ +P++V G G+G+AV+PLTLS +AGVG ++IGP++A+A + Q+LGG + L
Sbjct  350  TDAPDYFPSIFLPVIVIGFGVGLAVIPLTLSVVAGVGPNEIGPLTALAQVAQNLGGAVGL  409

Query  452  AVIQAVITSRTLYLGGTTGPVKFMNDVQLAALDHAYTYGLLWVAGAAIIVGGMALFIGYT  511
             V+ A++TSR L  GGTT PV+ MN  QLAA    Y       AG A+I   + LF+ +T
Sbjct  410  VVVGAMVTSRALSKGGTTEPVETMNPTQLAAQAEGYGLAFAACAGIAVIAAIVVLFMRFT  469

Query  512  PQQVAHAQEVKEAIDAG  528
            P+QVA  Q  +EA DAG
Sbjct  470  PEQVAEGQAAQEAADAG  486


>gi|317508516|ref|ZP_07966183.1| major facilitator superfamily transporter [Segniliparus rugosus 
ATCC BAA-974]
 gi|316253207|gb|EFV12610.1| major facilitator superfamily transporter [Segniliparus rugosus 
ATCC BAA-974]
Length=571

 Score =  363 bits (932),  Expect = 4e-98, Method: Compositional matrix adjust.
 Identities = 220/494 (45%), Positives = 314/494 (64%), Gaps = 16/494 (3%)

Query  48   SRSFIAAVIAIGGMQLLATMDSTVAIVALPKIQNELSLSDAGRSWVITAYVLTFGGLMLL  107
            S +F  A++A+GGMQ +AT+D TVA +AL +I + L LS  GRSWVIT+YVL FGGLMLL
Sbjct  73   SSAFGLAILALGGMQFMATLDGTVANIALYRISDALHLSGPGRSWVITSYVLAFGGLMLL  132

Query  108  GGRLGDTIGRKRTFIVGVALFTISSVLCAVAWDEATLVIARLSQGVGSAIASPTGLALVA  167
            GGR+GD IGRKR F++GV +FT+ S+LC+++W+E +L+  R  QG G+AIA+PTGLA+VA
Sbjct  133  GGRIGDLIGRKRAFLIGVGVFTLGSLLCSLSWNEISLLAFRAFQGSGAAIAAPTGLAIVA  192

Query  168  TTFPKGPARNAATAVFAAMTAIGSVMGLVVGGALTE-------------VSWRWAFLVNV  214
            + +  G ARN A A++  M  IGS+ GL+ GGALTE             + W+  F VNV
Sbjct  193  SLYTPGSARNVAVAIYGGMLGIGSIAGLIFGGALTELGRFIGEHIGISGLDWQLIFAVNV  252

Query  215  PIGLVMIYLARTALRETNKERMKLDATGAILATLACTAAVFAFSIGPEKGWMSGITIGSG  274
            PIG+ ++ L    +        KLD  GA+ +  A  + VF F+ GP  GW S   +G  
Sbjct  253  PIGVGILVLTALTIPNIPPHSTKLDVPGALSSVGAVLSFVFGFTQGPIWGWTSPFVVGPL  312

Query  275  LVALAAAVAFVIVERTAENPVVPFHLFRDRNRLVTFSAILLAGGVMFSLTVCIGLYVQDI  334
            ++ +A   AFV +E  + NP+VP  LF  ++++ TF+ I+L+G ++  LT+ + L+ QD+
Sbjct  313  ILGVALLAAFVAIELRSSNPLVPLRLFATKDKIATFTTIILSGAILMCLTIYVVLFFQDV  372

Query  335  LGYSALRAGVGFIPFVIAMGIGLGVSSQLVSRFSPRVLTIGGGYLLFGAMLYGSFFMHRG  394
            L YS L+ G+ FIPF IA+GIG  V+  L+ + +PR     G   +    LYGS  +   
Sbjct  373  LHYSPLKTGLSFIPFAIALGIGSQVAVLLLKKIAPRWTAGVGLAFVLAGFLYGS-TLTPS  431

Query  395  VPYFPNLVMPIVVGGIGIGMAVVPLTLSAIAGVGFDQIGPVSAIALMLQSLGGPLVLAVI  454
              Y  NL+ PI++ G GIG+ +VPL L  + GV   ++GPV+AIAL+ Q LGGP+ L+++
Sbjct  432  AQYLHNLLAPILLIGFGIGVVLVPLPLCVLVGVPDSELGPVAAIALVAQELGGPVGLSLM  491

Query  455  QAVITSRTLYLGGTTGPVKFMNDVQLAALDHAYTYGLLWVAGAAIIVGGMALFIGYTPQQ  514
             A++ S  L +G +      M   QLA L   YT+GLL +AGAA++ G   LFIGYT  Q
Sbjct  492  GAMLFSTKLEVGRSNS--DGMTAEQLAQLSSGYTFGLLILAGAALVAGASGLFIGYTSAQ  549

Query  515  VAHAQEVKEAIDAG  528
            +A AQE K A D+G
Sbjct  550  IAEAQEAKAAADSG  563


>gi|296139419|ref|YP_003646662.1| major facilitator superfamily protein [Tsukamurella paurometabola 
DSM 20162]
 gi|296027553|gb|ADG78323.1| major facilitator superfamily MFS_1 [Tsukamurella paurometabola 
DSM 20162]
Length=733

 Score =  354 bits (908),  Expect = 2e-95, Method: Compositional matrix adjust.
 Identities = 213/485 (44%), Positives = 300/485 (62%), Gaps = 12/485 (2%)

Query  54   AVIAIGGMQLLATMDSTVAIVALPKIQNELSLSDAGRSWVITAYVLTFGGLMLLGGRLGD  113
            A+  + GM  LA +D TV  VA+P IQ  L+L+DA + WV  AY LTFGG MLLGGRLGD
Sbjct  20   AIFVLSGMYFLAVLDGTVVFVAMPAIQEALNLTDAMKVWVFGAYALTFGGFMLLGGRLGD  79

Query  114  TIGRKRTFIVGVALFTISSVLCAVAWDEATLVIARLSQGVGSAIASPTGLALVATTFPKG  173
            T GRK+ FI+GV  FT++S L   A  EA ++ AR SQG  +AIASPT LAL+ATTF  G
Sbjct  80   TFGRKKMFILGVFGFTVASALAGFATSEAWMLAARASQGFFAAIASPTALALIATTFAPG  139

Query  174  PARNAATAVFAAMTAIGSVMGLVVGGALTEVSWRWAFLVNVPIGLVMIYLARTALRE-TN  232
             ARN A  +F  M  +GSV GLV GG L    WR  F +NVP+GL        AL E T+
Sbjct  140  KARNQAFGIFGGMAGLGSVAGLVAGGLLATWDWRLVFWINVPVGLACAIGGYFALDEATS  199

Query  233  KERMKLDATGAILATLACTAAVFAFSIGPEKGWMSGITIGSGLVALAAAVAFVIVERTAE  292
            + R  LD  GA+LA   C A V+A + GPE  W S +   +  V++    AF++VERTA+
Sbjct  200  ERRHALDVKGAVLAVAGCVAGVYALTSGPELHWRSPLVYAALGVSVVCLTAFLVVERTAK  259

Query  293  NPVVPFHLFRDRNRLVTFSAILLAGGVMFSLTVCIGLYVQDILGYSALRAGVGFIPFVIA  352
            NP++PF LF +RNR+     IL+ G ++ +L   + L  Q +LGYS L++G+  +PF + 
Sbjct  260  NPILPFSLFNNRNRVAAMIGILVCGALIPTLGFYVALTFQLVLGYSPLQSGLALLPFAVG  319

Query  353  MGIGLGVSSQLVSRFSPRVLTIGGGYLLFGAMLYGSFFMHRG---VPYFPNLVMPIVVGG  409
            MGI +  S++LV     R L   GG ++F   LY    M +    V YFP + +P+ + G
Sbjct  320  MGISITASTKLVQYIQARWLVAIGGLIVFFPCLYVPSLMSKAPETVAYFPQIGVPVFLIG  379

Query  410  IGIGMAVVPLTLSAIAGVGFDQIGPVSAIALMLQSLGGPLVLAVIQAVITSRTLYLGG-T  468
            +G+G A+VPL L A+AGV   +IGP+SA+  + Q+LGG + LA +Q V+TSR +  GG T
Sbjct  380  LGVGFAIVPLPLCALAGVRPTEIGPMSALIEVGQNLGGIIGLASVQVVVTSRIMAEGGPT  439

Query  469  TGPVKF--MNDVQLAALDHAYTYGLLWVAGAAI-IVGGMAL--FIGYTPQQVAHAQEVKE  523
            TG +K   ++  Q++AL  A  YGL +++ A I I+ G+ +  F+ +TP ++A  Q  + 
Sbjct  440  TGHLKHSTLSPDQISAL--ASGYGLAFISCAVILIIAGLVVVPFMRFTPAEIAEGQMAEA  497

Query  524  AIDAG  528
            +  +G
Sbjct  498  SSKSG  502


>gi|54026047|ref|YP_120289.1| putative transporter [Nocardia farcinica IFM 10152]
 gi|54017555|dbj|BAD58925.1| putative transporter [Nocardia farcinica IFM 10152]
Length=494

 Score =  346 bits (888),  Expect = 5e-93, Method: Compositional matrix adjust.
 Identities = 227/488 (47%), Positives = 314/488 (65%), Gaps = 1/488 (0%)

Query  36   ERPSRYYPTWLPSRSFIAAVIAIGGMQLLATMDSTVAIVALPKIQNELSLSDAGRSWVIT  95
            E P+      +  R+F  A++ + G+QL+  +D TV I ALP++Q+++ LS AG +W++T
Sbjct  3    ENPAATTQFPVTQRAFGLAILVLSGLQLMVVLDGTVVIFALPRLQDQMGLSSAGSAWIVT  62

Query  96   AYVLTFGGLMLLGGRLGDTIGRKRTFIVGVALFTISSVLCAVAWDEATLVIARLSQGVGS  155
            AY LTF GLMLLGGRLGD  GRKR  I GV LFT++S+LC +A  +A L+ AR  QG G+
Sbjct  63   AYGLTFAGLMLLGGRLGDAFGRKRMLIAGVGLFTVASLLCGLAHWQAMLIAARALQGAGA  122

Query  156  AIASPTGLALVATTFPKGPARNAATAVFAAMTAIGSVMGLVVGGALTEVSWRWAFLVNVP  215
            AIA+P   ALVATTF  G ARN A A+  +M  IGSV GLVVGGALT++SWRW FL+NVP
Sbjct  123  AIAAPVAFALVATTFAPGKARNQAIAIVGSMVGIGSVGGLVVGGALTQLSWRWIFLINVP  182

Query  216  IGLVMIYLARTALRETNKERMKLDATGAILATLACTAAVFAFSIGPEKGWMSGITIGSGL  275
            IG ++I  A   L +T   R+ LDA GA+L TLAC A VF  + GPE GW     IG+ +
Sbjct  183  IGALIILGAIYCLADTGHHRVALDARGAVLGTLACAAIVFGATEGPELGWSHPAVIGALI  242

Query  276  VALAAAVAFVIVERTAENPVVPFHLFRDRNRLVTFSAILLAGGVMFSLTVCIGLYVQDIL  335
                  V FVI ER  ++P++P+ LF  R+R+ TF  ILLAGGV+ ++T  +  ++Q++L
Sbjct  243  GGAILLVVFVIAERNVDDPLLPWSLFDSRDRVTTFVLILLAGGVLGAMTYFVAQFLQNVL  302

Query  336  GYSALRAGVGFIPFVIAMGIGLGVSSQLVSRFSPRVLTIGGGYLLFGAMLYGSFFMHRGV  395
            GY  L+AGV  IPF + +GIG  ++S+L    +PR L  G   +L   +L+GS  +   V
Sbjct  303  GYGPLQAGVASIPFTVGIGIGGALASKLAMTVAPRWLLFGAALVLAVGLLFGS-TLDGEV  361

Query  396  PYFPNLVMPIVVGGIGIGMAVVPLTLSAIAGVGFDQIGPVSAIALMLQSLGGPLVLAVIQ  455
             Y P L+  ++V G G+G+A+V   L  + GV    IGP+SA+  M  +LG P+ + ++ 
Sbjct  362  SYLPTLLPLLIVIGFGVGVAMVVTPLCVLVGVPPSDIGPLSAVGQMFMNLGTPMAIGILT  421

Query  456  AVITSRTLYLGGTTGPVKFMNDVQLAALDHAYTYGLLWVAGAAIIVGGMALFIGYTPQQV  515
             V  SRTL LGGTTG V  M D Q+ AL   YT  L   AG A ++G +AL + +TP+Q+
Sbjct  422  PVAVSRTLSLGGTTGKVSAMTDAQIVALGEGYTLVLAVCAGVAAVIGLIALTLRFTPEQI  481

Query  516  AHAQEVKE  523
            A AQ  +E
Sbjct  482  ARAQHAQE  489


>gi|296394269|ref|YP_003659153.1| major facilitator superfamily protein [Segniliparus rotundus 
DSM 44985]
 gi|296181416|gb|ADG98322.1| major facilitator superfamily MFS_1 [Segniliparus rotundus DSM 
44985]
Length=569

 Score =  345 bits (885),  Expect = 1e-92, Method: Compositional matrix adjust.
 Identities = 203/478 (43%), Positives = 299/478 (63%), Gaps = 17/478 (3%)

Query  48   SRSFIAAVIAIGGMQLLATMDSTVAIVALPKIQNELSLSDAGRSWVITAYVLTFGGLMLL  107
            + +F  A++A+GGMQ +AT+D TVA +AL +I   L LS  GRSWVIT+YVL FGGLML+
Sbjct  70   ASAFGLAILALGGMQFMATLDGTVANIALYRIGEALRLSGPGRSWVITSYVLAFGGLMLI  129

Query  108  GGRLGDTIGRKRTFIVGVALFTISSVLCAVAWDEATLVIARLSQGVGSAIASPTGLALVA  167
            GGR+GD IGRKR F++GV +FT+ S+LC+++WDEA+L++ R  QG G+A+ASPTGLALVA
Sbjct  130  GGRIGDLIGRKRAFLLGVGIFTLGSLLCSLSWDEASLLVFRAFQGSGAALASPTGLALVA  189

Query  168  TTFPKGPARNAATAVFAAMTAIGSVMGLVVGGALTE-------------VSWRWAFLVNV  214
            T +  G ARN A A++  M  IGS+ GL+ GGALTE             + W+  F VNV
Sbjct  190  TLYKPGTARNMAVAIYGGMLGIGSIAGLIFGGALTELGRFIGDHVGISGLDWQLIFAVNV  249

Query  215  PIGLVMIYLARTALRETNKERMKLDATGAILATLACTAAVFAFSIGPEKGWMSGITIGSG  274
            P+G+ ++ L    +        KLD  GA  +  A  A VF F+ GP  GW S   +   
Sbjct  250  PVGIGILVLTALTIPNVAPNSTKLDLPGAAASAGAVFAFVFGFTQGPIWGWDSPWIVAPL  309

Query  275  LVALAAAVAFVIVERTAENPVVPFHLFRDRNRLVTFSAILLAGGVMFSLTVCIGLYVQDI  334
             +     VAF ++E  + NP++P  LF +++++ TF  I+L+G ++  LT+ + L+ QD+
Sbjct  310  ALGAVLLVAFFVIELRSPNPLLPLRLFANKDKIATFGTIILSGAILMCLTIYVVLFFQDV  369

Query  335  LGYSALRAGVGFIPFVIAMGIGLGVSSQLVSRFSPRVLTIGGGYLLFGAMLYGSFFMHRG  394
            L YS L+ G+ FIPF +A+GIG  V+  L+ + +PR     G   +    L GS  +   
Sbjct  370  LHYSPLKTGLSFIPFAVALGIGSQVAVLLLKKIAPRWTAGVGLVFVLAGFLDGS-TLTPS  428

Query  395  VPYFPNLVMPIVVGGIGIGMAVVPLTLSAIAGVGFDQIGPVSAIALMLQSLGGPLVLAVI  454
              Y  +L+ PI++ G G+G+ +VPL L A+ G+  +++G ++AIAL+ Q LGGP+ L+V+
Sbjct  429  ASYTHDLLAPILLIGFGVGVVLVPLPLCALVGIPDEEVGALAAIALVAQELGGPIGLSVM  488

Query  455  QAVI-TSRTLYLGGTTGPVKFMNDVQLAALDHAYTYGLLWVAGAAIIVGGMALFIGYT  511
             AV+ T + L +G +      M+  QLA L   YT+GLL +AG A++      FIGYT
Sbjct  489  GAVLFTGQKLEVGHSNS--AGMSPEQLAQLSSGYTFGLLILAGVALVAAVTGFFIGYT  544


>gi|227488646|ref|ZP_03918962.1| major facilitator superfamily multidrug transporter [Corynebacterium 
glucuronolyticum ATCC 51867]
 gi|227091540|gb|EEI26852.1| major facilitator superfamily multidrug transporter [Corynebacterium 
glucuronolyticum ATCC 51867]
Length=496

 Score =  316 bits (810),  Expect = 6e-84, Method: Compositional matrix adjust.
 Identities = 209/501 (42%), Positives = 313/501 (63%), Gaps = 13/501 (2%)

Query  35   SERPSRYYPTWLPSRSFIAAVIAIGGMQLLATMDSTVAIVALPKIQNELSLSDAGRSWVI  94
            S +P   YP  +   ++   +I +  +QL+  +D TV  +AL +IQ +L L+D  RSWV+
Sbjct  2    SNKPQTSYP--VTGSAYGWPLIVLCALQLMVVLDGTVVNLALARIQQDLGLTDELRSWVV  59

Query  95   TAYVLTFGGLMLLGGRLGDTIGRKRTFIVGVALFTISSVLCAVAWDEATLVIARLSQGVG  154
            TAY L +GGL+LLGGR+GD  GRKR F++GV LFT++S+ C +      L++AR+ QG+G
Sbjct  60   TAYALAYGGLLLLGGRIGDVFGRKRVFLIGVGLFTVASLACGLTNSAILLLVARVVQGLG  119

Query  155  SAIASPTGLALVATTFPKGPARNAATAVFAAMTAIGSVMGLVVGGALTEVSWRWAFLVNV  214
            +AIASPT +AL+  TF  G  RN A +VFA MT +GSV+GLV+GGALT+ SWRW FL+NV
Sbjct  120  AAIASPTAMALLVVTFAPGKPRNQAFSVFAMMTGLGSVLGLVIGGALTQASWRWIFLINV  179

Query  215  PIGLVMIYLARTALRET-NKERMKLDATGAILATLACTAAVFAFSIGPEKGWMSGITIGS  273
            PIGL+++      LR   ++  + LD  GAILAT A T  VF  S G      S + + S
Sbjct  180  PIGLLIVVAGMKYLRHPGDRATITLDVRGAILATAASTLLVFGLSAGGGG--ASPLIVAS  237

Query  274  GLVALAAAVAFVIVERTAENPVVPFHLFRDRNRLVTFSAILLAGGVMFSLTVCIGLYVQD  333
             ++     V F + +R A +PV+P  +F +R+R   F  +LL G +M ++TV + L+VQ+
Sbjct  238  LMLGAVLLVLFFLSQRKASHPVLPLSMFANRSRAAVFVCLLLVGALMMAMTVQVALFVQE  297

Query  334  ILGYSALRAGVGFIPFVIAMGIGLGVSSQLVSRFSPRVLTIGGGYLLFGAMLYGSFFMHR  393
            +L Y+ L+AG+ FIPF  A+G G GV+ +L    +PR +  GGG +L G  +YGS  +  
Sbjct  298  VLQYTPLQAGLAFIPFAFALGAGSGVAGKLAETVAPRFIAAGGGVILVGGFIYGS-TLDM  356

Query  394  GVPYFPNLVMPIVVGGIGIGMAVVPLTLSAIAGVGFDQIGPVSAIALMLQSLGGPLVLAV  453
               Y+P+L++PI++ G GIG+ ++PLTLS +AGV  D++GP++A +L+ Q+LGGPL LA 
Sbjct  357  TASYWPDLLVPILIIGAGIGIILIPLTLSVVAGVKPDEVGPLTATSLVSQTLGGPLGLAG  416

Query  454  IQAVITSRTLYLGGTTGPVKFMN-----DVQLAALDHAYTYGLLWVAG-AAIIVGGMALF  507
            + A    R +  G      + +N     +VQ AAL   YT  LL  A  AA +V    + 
Sbjct  417  VTA-FAERVVRSGLGDAAFETLNRSALTEVQRAALGQGYTDSLLICAALAACVVVICLVL  475

Query  508  IGYTPQQVAHAQEVKEAIDAG  528
            + +TP+ +   ++ +E  + G
Sbjct  476  VRFTPEDIREGKKAEELANQG  496


>gi|227543249|ref|ZP_03973298.1| major facilitator superfamily multidrug transporter [Corynebacterium 
glucuronolyticum ATCC 51866]
 gi|227181058|gb|EEI62030.1| major facilitator superfamily multidrug transporter [Corynebacterium 
glucuronolyticum ATCC 51866]
Length=496

 Score =  315 bits (806),  Expect = 2e-83, Method: Compositional matrix adjust.
 Identities = 208/501 (42%), Positives = 312/501 (63%), Gaps = 13/501 (2%)

Query  35   SERPSRYYPTWLPSRSFIAAVIAIGGMQLLATMDSTVAIVALPKIQNELSLSDAGRSWVI  94
            S +P   YP  +   ++   +I +  +QL+  +D TV  +AL +IQ +L L+D  RSWV+
Sbjct  2    SNKPQTSYP--VTGSAYGWPLIVLCALQLMVVLDGTVVNLALARIQQDLGLTDELRSWVV  59

Query  95   TAYVLTFGGLMLLGGRLGDTIGRKRTFIVGVALFTISSVLCAVAWDEATLVIARLSQGVG  154
            TAY L +GGL+LLGGR+GD  GRKR F++GV LFT++S+ C +      L++AR+ QG+G
Sbjct  60   TAYALAYGGLLLLGGRIGDVFGRKRVFLIGVGLFTVASLACGLTNSAILLLVARVVQGLG  119

Query  155  SAIASPTGLALVATTFPKGPARNAATAVFAAMTAIGSVMGLVVGGALTEVSWRWAFLVNV  214
            +AIASPT +AL+  TF  G  RN A +VFA MT +GSV+GLV+GGALT+ SWRW FL+NV
Sbjct  120  AAIASPTAMALLVVTFAPGKPRNQAFSVFAMMTGLGSVLGLVIGGALTQASWRWIFLINV  179

Query  215  PIGLVMIYLARTALRET-NKERMKLDATGAILATLACTAAVFAFSIGPEKGWMSGITIGS  273
            PIGL+++      LR   ++  + LD  GAILAT A T  VF  S G      S + + S
Sbjct  180  PIGLLIVVAGMKYLRHPGDRATITLDVRGAILATAASTLLVFGLSAGGGG--ASPLIVAS  237

Query  274  GLVALAAAVAFVIVERTAENPVVPFHLFRDRNRLVTFSAILLAGGVMFSLTVCIGLYVQD  333
             ++     V F + +R A +PV+P  +F +R+R   F  + L G +M ++TV + L+VQ+
Sbjct  238  LMLGAVLLVLFFLSQRKASHPVLPLSMFANRSRAAVFVCLFLVGALMMAMTVQVALFVQE  297

Query  334  ILGYSALRAGVGFIPFVIAMGIGLGVSSQLVSRFSPRVLTIGGGYLLFGAMLYGSFFMHR  393
            +L Y+ L+AG+ FIPF  A+G G GV+ +L    +PR +  GGG +L G  +YGS  +  
Sbjct  298  VLQYTPLQAGLAFIPFAFALGAGSGVAGKLAETVAPRFIAAGGGVILVGGFIYGS-TLDM  356

Query  394  GVPYFPNLVMPIVVGGIGIGMAVVPLTLSAIAGVGFDQIGPVSAIALMLQSLGGPLVLAV  453
               Y+P+L++PI++ G GIG+ ++PLTLS +AGV  D++GP++A +L+ Q+LGGPL LA 
Sbjct  357  TASYWPDLLVPILIIGAGIGIILIPLTLSVVAGVKPDEVGPLTATSLVSQTLGGPLGLAG  416

Query  454  IQAVITSRTLYLGGTTGPVKFMN-----DVQLAALDHAYTYGLLWVAG-AAIIVGGMALF  507
            + A    R +  G      + +N     +VQ AAL   YT  LL  A  AA +V    + 
Sbjct  417  VTA-FAERVVRSGLGDAAFETLNRSALTEVQRAALGQGYTDSLLICAALAACVVVICLVL  475

Query  508  IGYTPQQVAHAQEVKEAIDAG  528
            + +TP+ +   ++ +E  + G
Sbjct  476  VRFTPEDIREGKKAEELANQG  496


>gi|158317950|ref|YP_001510458.1| EmrB/QacA family drug resistance transporter [Frankia sp. EAN1pec]
 gi|158113355|gb|ABW15552.1| drug resistance transporter, EmrB/QacA subfamily [Frankia sp. 
EAN1pec]
Length=508

 Score =  273 bits (699),  Expect = 5e-71, Method: Compositional matrix adjust.
 Identities = 183/472 (39%), Positives = 279/472 (60%), Gaps = 16/472 (3%)

Query  30   SEETASERPSRYYPTWLP--SRSFIAAVIAIGGMQLLATMDSTVAIVALPKIQNELSLSD  87
            S ++A+  P R   +  P  S     A+  I   QL+  +D+T+  +ALP IQ +L +SD
Sbjct  2    SADSATAAPVRPGTSAAPPTSHHLGLALFVIAAAQLVVVLDATITNIALPSIQTDLDVSD  61

Query  88   AGRSWVITAYVLTFGGLMLLGGRLGDTIGRKRTFIVGVALFTISSVLCAVAWDEATLVIA  147
            A  +W++ +Y L FGGL+LLGGR GD  GR+R F  G+A+FT++S+L  +A +EA L+ A
Sbjct  62   ANLAWIVNSYALAFGGLLLLGGRTGDLFGRRRMFQTGIAIFTLASLLGGLAPNEALLISA  121

Query  148  RLSQGVGSAIASPTGLALVATTFPKGPARNAATAVFAAMTAIGSVMGLVVGGALTEV-SW  206
            R+ QG+G+A+A+P  LAL+ TTFP G  RN A  V+AAM  +G+ +GL++GG LT+V SW
Sbjct  122  RVLQGIGAALAAPNALALITTTFPPGKPRNTAMGVYAAMGGVGATVGLLLGGTLTDVLSW  181

Query  207  RWAFLVNVPIGLVMIYLARTALRETNKERMKLDATGAILATLACTAAVFAFSIGPEKGWM  266
            RW F +NVPIGLV++   R+ L E  ++  ++D  GA+  T    A V+  + G E GW 
Sbjct  182  RWVFFINVPIGLVVLVGTRS-LVEAERDPGRVDVPGAVTGTGGLIALVYGITHGGEHGWS  240

Query  267  SGITIGSGLVALAAAVAFVIVERTAENPVVPFHLFRDRNRLVTFSAILLAGGVMFSLTVC  326
               T+ +  VA    VAF++++    +P++P  LF+DRNR  +++ +LL G  MF+    
Sbjct  241  DSATLTAFAVAAVLLVAFLLIQARTAHPMMPLRLFQDRNRSGSYATMLLIGAGMFATFYF  300

Query  327  IGLYVQDILGYSALRAGVGFIPFVIAMGIGLGVSSQLVSRFSPRVLTIGGGYLLFGAMLY  386
            + LY+Q ILGYS +R G  ++PF   + I  GVSS+LV+  +PRV+   G       ML+
Sbjct  301  LTLYMQLILGYSPVRTGFAYLPFSFGIAIAAGVSSKLVTHVAPRVIAGPGLLAAAAGMLW  360

Query  387  GSFFMHRGVPYFPNLVMPIVVGGIGIGMAVVPLTLSAIAGVGFDQIGPVSAIALMLQSLG  446
             +  +    PY  +L+  + + G+G+G++ VP+TL A++ V  +  G  SA+    Q +G
Sbjct  361  FA-ALDPDSPYAGHLMPAMFLTGLGLGLSFVPMTLGAVSDVAHEDSGIASALLNTAQQIG  419

Query  447  GPLVLAVIQAVITSR----------TLYLGGTTGPVKFMNDVQLAALDHAYT  488
            G L LAV+  + TS            LY G  T  V  +   Q  AL H Y+
Sbjct  420  GALGLAVLSTIATSTADNKLPEAAGALYQGLATNDVILIARAQ-DALTHGYS  470


>gi|328885854|emb|CCA59093.1| MFS family multidrug efflux protein [Streptomyces venezuelae 
ATCC 10712]
Length=519

 Score =  269 bits (687),  Expect = 1e-69, Method: Compositional matrix adjust.
 Identities = 157/405 (39%), Positives = 237/405 (59%), Gaps = 2/405 (0%)

Query  54   AVIAIGGMQLLATMDSTVAIVALPKIQNELSLSDAGRSWVITAYVLTFGGLMLLGGRLGD  113
            A+  I   QL+  +D T+  +ALP IQ  L  S    SWV+ AY LTFGGL+LLGGR GD
Sbjct  26   ALFVIASCQLMVVLDITIVNIALPHIQTALDFSTTSLSWVVNAYTLTFGGLLLLGGRAGD  85

Query  114  TIGRKRTFIVGVALFTISSVLCAVAWDEATLVIARLSQGVGSAIASPTGLALVATTFPKG  173
             +GR+R FI GV LF ++S+ C +A  E  L+ AR  QGVG AIASPT L+L+ TTF +G
Sbjct  86   ILGRRRVFIFGVLLFGLASLFCGLAQSEWQLLAARALQGVGGAIASPTSLSLITTTFDEG  145

Query  174  PARNAATAVFAAMTAIGSVMGLVVGGALTE-VSWRWAFLVNVPIGLVMIYLARTALRETN  232
            P RN A  VFA ++A G  +GLV GG L + + WRW F VNVPI L++ +L    ++E+ 
Sbjct  146  PERNRAFGVFAGVSAGGGAIGLVAGGMLVQWLDWRWIFFVNVPIALIIAFLTPRHVKESE  205

Query  233  KERMKLDATGAILATLACTAAVFAFSIGPEKGWMSGITIGSGLVALAAAVAFVIVERTAE  292
            +     D  GA+ +TL   A V+ F    ++GW    TIGS + A+     F+++ER ++
Sbjct  206  RHPGHFDLAGALTSTLGMVALVYGFIRAAQEGWSDPYTIGSFVAAVVLLALFILIERRSQ  265

Query  293  NPVVPFHLFRDRNRLVTFSAILLAGGVMFSLTVCIGLYVQDILGYSALRAGVGFIPFVIA  352
             P+ P H+F DRNR  T+  +L     +F +   + L+VQ +L +S L  G+ F+P    
Sbjct  266  QPITPLHMFADRNRSGTYVIMLCLAAAIFGMFFFLTLFVQQVLSFSPLTTGLAFLPVSAI  325

Query  353  MGIGLGVSSQLVSRFSPRVLTIGGGYLLFGAMLYGSFFMHRGVPYFPNLVMPIVVGGIGI  412
            +G+G G++S L+ R+ P+   + G  L    + + +        Y  +++ PI+V G+G+
Sbjct  326  IGVGAGLTSNLLPRYGPKPFMVTGSVLAAAGLSWLT-LTDVDSTYLGSILGPILVFGLGM  384

Query  413  GMAVVPLTLSAIAGVGFDQIGPVSAIALMLQSLGGPLVLAVIQAV  457
            G+  V LT+ A++ V   + G  S +    Q +GG L L+++  V
Sbjct  385  GLMFVSLTIMALSNVEVQESGAASGLLNATQQVGGSLGLSILVTV  429



Lambda     K      H
   0.325    0.139    0.413 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Effective search space used: 1168347732056


  Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
    Posted date:  Sep 5, 2011  4:36 AM
  Number of letters in database: 5,219,829,388
  Number of sequences in database:  15,229,318



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40