BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv2868c Length=387 Score E Sequences producing significant alignments: (Bits) Value gi|15610005|ref|NP_217384.1| 4-hydroxy-3-methylbut-2-en-1-yl dip... 780 0.0 gi|340627861|ref|YP_004746313.1| putative GCPE protein [Mycobact... 778 0.0 gi|31794045|ref|NP_856538.1| 4-hydroxy-3-methylbut-2-en-1-yl dip... 776 0.0 gi|167969497|ref|ZP_02551774.1| 4-hydroxy-3-methylbut-2-en-1-yl ... 770 0.0 gi|183981851|ref|YP_001850142.1| 4-hydroxy-3-methylbut-2-en-1-yl... 746 0.0 gi|240171738|ref|ZP_04750397.1| 4-hydroxy-3-methylbut-2-en-1-yl ... 744 0.0 gi|296171529|ref|ZP_06852793.1| 4-hydroxy-3-methylbut-2-en-1-yl ... 718 0.0 gi|41409036|ref|NP_961872.1| 4-hydroxy-3-methylbut-2-en-1-yl dip... 713 0.0 gi|342858280|ref|ZP_08714935.1| 4-hydroxy-3-methylbut-2-en-1-yl ... 711 0.0 gi|254776154|ref|ZP_05217670.1| 4-hydroxy-3-methylbut-2-en-1-yl ... 705 0.0 gi|118617655|ref|YP_905987.1| 4-hydroxy-3-methylbut-2-en-1-yl di... 704 0.0 gi|254819030|ref|ZP_05224031.1| 4-hydroxy-3-methylbut-2-en-1-yl ... 698 0.0 gi|54026089|ref|YP_120331.1| 4-hydroxy-3-methylbut-2-en-1-yl dip... 697 0.0 gi|118468236|ref|YP_886917.1| 4-hydroxy-3-methylbut-2-en-1-yl di... 694 0.0 gi|169630251|ref|YP_001703900.1| 4-hydroxy-3-methylbut-2-en-1-yl... 689 0.0 gi|108799011|ref|YP_639208.1| 4-hydroxy-3-methylbut-2-en-1-yl di... 687 0.0 gi|15827829|ref|NP_302092.1| 4-hydroxy-3-methylbut-2-en-1-yl dip... 684 0.0 gi|333991228|ref|YP_004523842.1| 4-hydroxy-3-methylbut-2-en-1-yl... 679 0.0 gi|120403253|ref|YP_953082.1| 4-hydroxy-3-methylbut-2-en-1-yl di... 679 0.0 gi|226366033|ref|YP_002783816.1| 4-hydroxy-3-methylbut-2-en-1-yl... 675 0.0 gi|145224661|ref|YP_001135339.1| 4-hydroxy-3-methylbut-2-en-1-yl... 674 0.0 gi|226306041|ref|YP_002766001.1| 4-hydroxy-3-methylbut-2-en-1-yl... 673 0.0 gi|118463746|ref|YP_882900.1| 4-hydroxy-3-methylbut-2-en-1-yl di... 672 0.0 gi|325673446|ref|ZP_08153137.1| 4-hydroxy-3-methylbut-2-en-1-yl ... 671 0.0 gi|262202053|ref|YP_003273261.1| 1-hydroxy-2-methyl-2-(E)-buteny... 671 0.0 gi|312139249|ref|YP_004006585.1| 4-hydroxy-3-methylbut-2-en-1-yl... 670 0.0 gi|333919260|ref|YP_004492841.1| 4-hydroxy-3-methylbut-2-en-1-yl... 668 0.0 gi|111023549|ref|YP_706521.1| 4-hydroxy-3-methylbut-2-en-1-yl di... 667 0.0 gi|326382910|ref|ZP_08204600.1| 4-hydroxy-3-methylbut-2-en-1-yl ... 666 0.0 gi|343926738|ref|ZP_08766235.1| 4-hydroxy-3-methylbut-2-en-1-yl ... 665 0.0 gi|319948048|ref|ZP_08022222.1| 4-hydroxy-3-methylbut-2-en-1-yl ... 657 0.0 gi|296139399|ref|YP_003646642.1| 1-hydroxy-2-methyl-2-(E)-buteny... 654 0.0 gi|284992357|ref|YP_003410911.1| 1-hydroxy-2-methyl-2-(E)-buteny... 649 0.0 gi|227833374|ref|YP_002835081.1| 4-hydroxy-3-methylbut-2-enyl di... 648 0.0 gi|183980306|ref|YP_001848597.1| GcpE protein [Mycobacterium mar... 644 0.0 gi|325001857|ref|ZP_08122969.1| 4-hydroxy-3-methylbut-2-en-1-yl ... 640 0.0 gi|337291018|ref|YP_004630039.1| 4-hydroxy-3-methylbut-2-en-1-yl... 639 0.0 gi|300858720|ref|YP_003783703.1| 4-hydroxy-3-methylbut-2-en-1-yl... 639 0.0 gi|68536242|ref|YP_250947.1| 4-hydroxy-3-methylbut-2-en-1-yl dip... 638 0.0 gi|260578942|ref|ZP_05846845.1| 4-hydroxy-3-methylbut-2-en-1-yl ... 637 0.0 gi|317506018|ref|ZP_07963848.1| GcpE protein [Segniliparus rugos... 636 1e-180 gi|336325808|ref|YP_004605774.1| 4-hydroxy-3-methylbut-2-en-1-yl... 635 3e-180 gi|38234077|ref|NP_939844.1| 4-hydroxy-3-methylbut-2-en-1-yl dip... 635 4e-180 gi|172040513|ref|YP_001800227.1| 4-hydroxy-3-methylbut-2-en-1-yl... 632 3e-179 gi|296394682|ref|YP_003659566.1| 1-hydroxy-2-methyl-2-(E)-buteny... 632 4e-179 gi|317125365|ref|YP_004099477.1| 4-hydroxy-3-methylbut-2-en-1-yl... 632 4e-179 gi|325962793|ref|YP_004240699.1| 4-hydroxy-3-methylbut-2-en-1-yl... 629 2e-178 gi|116669965|ref|YP_830898.1| 4-hydroxy-3-methylbut-2-en-1-yl di... 629 2e-178 gi|302525241|ref|ZP_07277583.1| 4-hydroxy-3-methylbut-2-en-1-yl ... 628 4e-178 gi|305681127|ref|ZP_07403934.1| 4-hydroxy-3-methylbut-2-en-1-yl ... 628 4e-178 >gi|15610005|ref|NP_217384.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Mycobacterium tuberculosis H37Rv] gi|15842410|ref|NP_337447.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Mycobacterium tuberculosis CDC1551] gi|121638750|ref|YP_978974.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Mycobacterium bovis BCG str. Pasteur 1173P2] 77 more sequence titles Length=387 Score = 780 bits (2014), Expect = 0.0, Method: Compositional matrix adjust. Identities = 386/387 (99%), Positives = 387/387 (100%), Gaps = 0/387 (0%) Query 1 VTVGLGMPQPPAPTLAPRRATRQLMVGNVGVGSDHPVSVQSMCTTKTHDVNSTLQQIAEL 60 +TVGLGMPQPPAPTLAPRRATRQLMVGNVGVGSDHPVSVQSMCTTKTHDVNSTLQQIAEL Sbjct 1 MTVGLGMPQPPAPTLAPRRATRQLMVGNVGVGSDHPVSVQSMCTTKTHDVNSTLQQIAEL 60 Query 61 TAAGCDIVRVACPRQEDADALAEIARHSQIPVVADIHFQPRYIFAAIDAGCAAVRVNPGN 120 TAAGCDIVRVACPRQEDADALAEIARHSQIPVVADIHFQPRYIFAAIDAGCAAVRVNPGN Sbjct 61 TAAGCDIVRVACPRQEDADALAEIARHSQIPVVADIHFQPRYIFAAIDAGCAAVRVNPGN 120 Query 121 IKEFDGRVGEVAKAAGAAGIPIRIGVNAGSLDKRFMEKYGKATPEALVESALWEASLFEE 180 IKEFDGRVGEVAKAAGAAGIPIRIGVNAGSLDKRFMEKYGKATPEALVESALWEASLFEE Sbjct 121 IKEFDGRVGEVAKAAGAAGIPIRIGVNAGSLDKRFMEKYGKATPEALVESALWEASLFEE 180 Query 181 HGFGDIKISVKHNDPVVMVAAYELLAARCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSR 240 HGFGDIKISVKHNDPVVMVAAYELLAARCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSR Sbjct 181 HGFGDIKISVKHNDPVVMVAAYELLAARCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSR 240 Query 241 GIGDTIRVSLSAPPVEEVKVGNQVLESLNLRPRSLEIVSCPSCGRAQVDVYTLANEVTAG 300 GIGDTIRVSLSAPPVEEVKVGNQVLESLNLRPRSLEIVSCPSCGRAQVDVYTLANEVTAG Sbjct 241 GIGDTIRVSLSAPPVEEVKVGNQVLESLNLRPRSLEIVSCPSCGRAQVDVYTLANEVTAG 300 Query 301 LDGLDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPEAQIVETLIE 360 LDGLDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPEAQIVETLIE Sbjct 301 LDGLDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPEAQIVETLIE 360 Query 361 EAMRLAAEMGEQDPGATPSGSPIVTVS 387 EAMRLAAEMGEQDPGATPSGSPIVTVS Sbjct 361 EAMRLAAEMGEQDPGATPSGSPIVTVS 387 >gi|340627861|ref|YP_004746313.1| putative GCPE protein [Mycobacterium canettii CIPT 140010059] gi|340006051|emb|CCC45221.1| putative GCPE protein [Mycobacterium canettii CIPT 140010059] Length=387 Score = 778 bits (2010), Expect = 0.0, Method: Compositional matrix adjust. Identities = 385/387 (99%), Positives = 387/387 (100%), Gaps = 0/387 (0%) Query 1 VTVGLGMPQPPAPTLAPRRATRQLMVGNVGVGSDHPVSVQSMCTTKTHDVNSTLQQIAEL 60 +TVGLGMPQPPAPTLAPRRATRQLMVGNVGVGSDHPVSVQSMCTTKTHDVNSTLQQIAEL Sbjct 1 MTVGLGMPQPPAPTLAPRRATRQLMVGNVGVGSDHPVSVQSMCTTKTHDVNSTLQQIAEL 60 Query 61 TAAGCDIVRVACPRQEDADALAEIARHSQIPVVADIHFQPRYIFAAIDAGCAAVRVNPGN 120 TAAGCDIVRVACPRQEDADALAEIARHSQIPVVADIHFQPRYIFAAIDAGCAAVRVNPGN Sbjct 61 TAAGCDIVRVACPRQEDADALAEIARHSQIPVVADIHFQPRYIFAAIDAGCAAVRVNPGN 120 Query 121 IKEFDGRVGEVAKAAGAAGIPIRIGVNAGSLDKRFMEKYGKATPEALVESALWEASLFEE 180 IKEFDGRVGEVAKAAGAAGIPIRIGVNAGSLDKRFMEKYGKATPEALVESALWEASLFEE Sbjct 121 IKEFDGRVGEVAKAAGAAGIPIRIGVNAGSLDKRFMEKYGKATPEALVESALWEASLFEE 180 Query 181 HGFGDIKISVKHNDPVVMVAAYELLAARCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSR 240 HGFGDIKISVKHNDPVVMVAAYELLAA+CDYPLHLGVTEAGPAFQGTIKSAVAFGALLSR Sbjct 181 HGFGDIKISVKHNDPVVMVAAYELLAAQCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSR 240 Query 241 GIGDTIRVSLSAPPVEEVKVGNQVLESLNLRPRSLEIVSCPSCGRAQVDVYTLANEVTAG 300 GIGDTIRVSLSAPPVEEVKVGNQVLESLNLRPRSLEIVSCPSCGRAQVDVYTLANEVTAG Sbjct 241 GIGDTIRVSLSAPPVEEVKVGNQVLESLNLRPRSLEIVSCPSCGRAQVDVYTLANEVTAG 300 Query 301 LDGLDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPEAQIVETLIE 360 LDGLDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPEAQIVETLIE Sbjct 301 LDGLDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPEAQIVETLIE 360 Query 361 EAMRLAAEMGEQDPGATPSGSPIVTVS 387 EAMRLAAEMGEQDPGATPSGSPIVTVS Sbjct 361 EAMRLAAEMGEQDPGATPSGSPIVTVS 387 >gi|31794045|ref|NP_856538.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Mycobacterium bovis AF2122/97] gi|50400946|sp|Q7TXN6.1|ISPG_MYCBO RecName: Full=4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; AltName: Full=1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase gi|31619640|emb|CAD96580.1| PROBABLE GCPE PROTEIN [Mycobacterium bovis AF2122/97] Length=387 Score = 776 bits (2005), Expect = 0.0, Method: Compositional matrix adjust. Identities = 385/387 (99%), Positives = 386/387 (99%), Gaps = 0/387 (0%) Query 1 VTVGLGMPQPPAPTLAPRRATRQLMVGNVGVGSDHPVSVQSMCTTKTHDVNSTLQQIAEL 60 +TVGLGMPQPPAPTLAPRRATRQLMVGNVGVGSDHPVSVQSMCTTKTHDVNSTLQQIAEL Sbjct 1 MTVGLGMPQPPAPTLAPRRATRQLMVGNVGVGSDHPVSVQSMCTTKTHDVNSTLQQIAEL 60 Query 61 TAAGCDIVRVACPRQEDADALAEIARHSQIPVVADIHFQPRYIFAAIDAGCAAVRVNPGN 120 TAAGCDIVRVACPRQEDADALAEIARHSQIPVVADIHFQPRYIFAAIDAGCAAVRVNPGN Sbjct 61 TAAGCDIVRVACPRQEDADALAEIARHSQIPVVADIHFQPRYIFAAIDAGCAAVRVNPGN 120 Query 121 IKEFDGRVGEVAKAAGAAGIPIRIGVNAGSLDKRFMEKYGKATPEALVESALWEASLFEE 180 IKEFDGRVGEVAKAAGAAGIPIRIGVNAGSLDKRFMEKYGKATPEALVESALWEASLFEE Sbjct 121 IKEFDGRVGEVAKAAGAAGIPIRIGVNAGSLDKRFMEKYGKATPEALVESALWEASLFEE 180 Query 181 HGFGDIKISVKHNDPVVMVAAYELLAARCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSR 240 HGFGDIKISVKHNDPVVMVAAYELLAARCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSR Sbjct 181 HGFGDIKISVKHNDPVVMVAAYELLAARCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSR 240 Query 241 GIGDTIRVSLSAPPVEEVKVGNQVLESLNLRPRSLEIVSCPSCGRAQVDVYTLANEVTAG 300 GIGDTIRVSLSAPPVEEVKVGNQVLESLNLRPRSLEIVSCPSCGRAQVDVYTLANEVTAG Sbjct 241 GIGDTIRVSLSAPPVEEVKVGNQVLESLNLRPRSLEIVSCPSCGRAQVDVYTLANEVTAG 300 Query 301 LDGLDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPEAQIVETLIE 360 LDGLDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPEAQIVETLIE Sbjct 301 LDGLDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPEAQIVETLIE 360 Query 361 EAMRLAAEMGEQDPGATPSGSPIVTVS 387 EAMRLAAEMGEQ PGATPSGSPIVTVS Sbjct 361 EAMRLAAEMGEQAPGATPSGSPIVTVS 387 >gi|167969497|ref|ZP_02551774.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Mycobacterium tuberculosis H37Ra] gi|294994039|ref|ZP_06799730.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Mycobacterium tuberculosis 210] gi|313659816|ref|ZP_07816696.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Mycobacterium tuberculosis KZN V2475] Length=381 Score = 770 bits (1989), Expect = 0.0, Method: Compositional matrix adjust. Identities = 381/381 (100%), Positives = 381/381 (100%), Gaps = 0/381 (0%) Query 7 MPQPPAPTLAPRRATRQLMVGNVGVGSDHPVSVQSMCTTKTHDVNSTLQQIAELTAAGCD 66 MPQPPAPTLAPRRATRQLMVGNVGVGSDHPVSVQSMCTTKTHDVNSTLQQIAELTAAGCD Sbjct 1 MPQPPAPTLAPRRATRQLMVGNVGVGSDHPVSVQSMCTTKTHDVNSTLQQIAELTAAGCD 60 Query 67 IVRVACPRQEDADALAEIARHSQIPVVADIHFQPRYIFAAIDAGCAAVRVNPGNIKEFDG 126 IVRVACPRQEDADALAEIARHSQIPVVADIHFQPRYIFAAIDAGCAAVRVNPGNIKEFDG Sbjct 61 IVRVACPRQEDADALAEIARHSQIPVVADIHFQPRYIFAAIDAGCAAVRVNPGNIKEFDG 120 Query 127 RVGEVAKAAGAAGIPIRIGVNAGSLDKRFMEKYGKATPEALVESALWEASLFEEHGFGDI 186 RVGEVAKAAGAAGIPIRIGVNAGSLDKRFMEKYGKATPEALVESALWEASLFEEHGFGDI Sbjct 121 RVGEVAKAAGAAGIPIRIGVNAGSLDKRFMEKYGKATPEALVESALWEASLFEEHGFGDI 180 Query 187 KISVKHNDPVVMVAAYELLAARCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSRGIGDTI 246 KISVKHNDPVVMVAAYELLAARCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSRGIGDTI Sbjct 181 KISVKHNDPVVMVAAYELLAARCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSRGIGDTI 240 Query 247 RVSLSAPPVEEVKVGNQVLESLNLRPRSLEIVSCPSCGRAQVDVYTLANEVTAGLDGLDV 306 RVSLSAPPVEEVKVGNQVLESLNLRPRSLEIVSCPSCGRAQVDVYTLANEVTAGLDGLDV Sbjct 241 RVSLSAPPVEEVKVGNQVLESLNLRPRSLEIVSCPSCGRAQVDVYTLANEVTAGLDGLDV 300 Query 307 PLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPEAQIVETLIEEAMRLA 366 PLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPEAQIVETLIEEAMRLA Sbjct 301 PLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPEAQIVETLIEEAMRLA 360 Query 367 AEMGEQDPGATPSGSPIVTVS 387 AEMGEQDPGATPSGSPIVTVS Sbjct 361 AEMGEQDPGATPSGSPIVTVS 381 >gi|183981851|ref|YP_001850142.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, IspG [Mycobacterium marinum M] gi|183175177|gb|ACC40287.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, IspG [Mycobacterium marinum M] Length=387 Score = 746 bits (1926), Expect = 0.0, Method: Compositional matrix adjust. Identities = 364/387 (95%), Positives = 380/387 (99%), Gaps = 0/387 (0%) Query 1 VTVGLGMPQPPAPTLAPRRATRQLMVGNVGVGSDHPVSVQSMCTTKTHDVNSTLQQIAEL 60 +T GLG+PQPPAPTL+PRR TRQLMV +VGVGSD+PVSVQSMCTTKTHDVN+TLQQIAEL Sbjct 1 MTTGLGIPQPPAPTLSPRRTTRQLMVRDVGVGSDYPVSVQSMCTTKTHDVNATLQQIAEL 60 Query 61 TAAGCDIVRVACPRQEDADALAEIARHSQIPVVADIHFQPRYIFAAIDAGCAAVRVNPGN 120 TAAGCDIVRVACPRQEDADALAEIARHSQIPV+ADIHFQP+YIFAAIDAGCAAVRVNPGN Sbjct 61 TAAGCDIVRVACPRQEDADALAEIARHSQIPVIADIHFQPKYIFAAIDAGCAAVRVNPGN 120 Query 121 IKEFDGRVGEVAKAAGAAGIPIRIGVNAGSLDKRFMEKYGKATPEALVESALWEASLFEE 180 IKEFDGRVGEVAKAAGAAGIPIRIGVNAGSLDKRFM+KYGKATPEALVESALWEASLFEE Sbjct 121 IKEFDGRVGEVAKAAGAAGIPIRIGVNAGSLDKRFMQKYGKATPEALVESALWEASLFEE 180 Query 181 HGFGDIKISVKHNDPVVMVAAYELLAARCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSR 240 HGFG+IKISVKHNDPV+MVAAYE LAA+CDYPLHLGVTEAGPAFQGTIKSAVAFGALLSR Sbjct 181 HGFGNIKISVKHNDPVIMVAAYEQLAAQCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSR 240 Query 241 GIGDTIRVSLSAPPVEEVKVGNQVLESLNLRPRSLEIVSCPSCGRAQVDVYTLANEVTAG 300 GIGDTIRVSLSAPPVEEVKVGNQ+LESLNLRPRSLEIVSCPSCGRAQVDVYTLANEVTAG Sbjct 241 GIGDTIRVSLSAPPVEEVKVGNQILESLNLRPRSLEIVSCPSCGRAQVDVYTLANEVTAG 300 Query 301 LDGLDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPEAQIVETLIE 360 LDGLDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPEAQIVETLIE Sbjct 301 LDGLDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPEAQIVETLIE 360 Query 361 EAMRLAAEMGEQDPGATPSGSPIVTVS 387 EAMR+AAEMG +DPG T SG+PIVTVS Sbjct 361 EAMRIAAEMGTEDPGTTSSGTPIVTVS 387 >gi|240171738|ref|ZP_04750397.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Mycobacterium kansasii ATCC 12478] Length=391 Score = 744 bits (1920), Expect = 0.0, Method: Compositional matrix adjust. Identities = 368/391 (95%), Positives = 382/391 (98%), Gaps = 4/391 (1%) Query 1 VTVGLGMPQ---PPAPTLAPRRATRQLMVGNVGVGSDHPVSVQSMCTTKTHDVNSTLQQI 57 +TVGLGMPQ PPAPTL+PRR+TRQLMVG+VGVGSDHP+SVQSMCTTKTHDVNSTLQQI Sbjct 1 MTVGLGMPQSPKPPAPTLSPRRSTRQLMVGDVGVGSDHPISVQSMCTTKTHDVNSTLQQI 60 Query 58 AELTAAGCDIVRVACPRQEDADALAEIARHSQIPVVADIHFQPRYIFAAIDAGCAAVRVN 117 AELTAAGCDIVRVACPRQEDADALAEIARHSQIPV+ADIHFQP+YIFAAIDAGCAAVRVN Sbjct 61 AELTAAGCDIVRVACPRQEDADALAEIARHSQIPVIADIHFQPKYIFAAIDAGCAAVRVN 120 Query 118 PGNIKEFDGRVGEVAKAAGAAGIPIRIGVNAGSLDKRFMEKYGKATPEALVESALWEASL 177 PGNIKEFDGRVGEVAKAAG AGIPIRIGVNAGSLDKRF++KYGKATPEALVESALWEASL Sbjct 121 PGNIKEFDGRVGEVAKAAGDAGIPIRIGVNAGSLDKRFLQKYGKATPEALVESALWEASL 180 Query 178 FEEHGFGDIKISVKHNDPVVMVAAYELLAARCDYPLHLGVTEAGPAFQGTIKSAVAFGAL 237 FEEHGFGDIKISVKHNDPVVMV AYELLAA+CDYPLHLGVTEAGPAFQGTIKSAVAFGAL Sbjct 181 FEEHGFGDIKISVKHNDPVVMVRAYELLAAQCDYPLHLGVTEAGPAFQGTIKSAVAFGAL 240 Query 238 LSRGIGDTIRVSLSAPPVEEVKVGNQVLESLNLRPRSLEIVSCPSCGRAQVDVYTLANEV 297 LS+GIGDTIRVSLSAPPVEEVKVGNQ+LESLNLRPR+LEIVSCPSCGRAQVDVYTLANEV Sbjct 241 LSKGIGDTIRVSLSAPPVEEVKVGNQILESLNLRPRTLEIVSCPSCGRAQVDVYTLANEV 300 Query 298 TAGLDGLDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPEAQIVET 357 TAGLDGLDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPEAQIVET Sbjct 301 TAGLDGLDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPEAQIVET 360 Query 358 LIEEAMRLAAEMG-EQDPGATPSGSPIVTVS 387 LIEEAMRLAAEM + DPGAT SGSPIVTVS Sbjct 361 LIEEAMRLAAEMAPDADPGATSSGSPIVTVS 391 >gi|296171529|ref|ZP_06852793.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295894091|gb|EFG73852.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Mycobacterium parascrofulaceum ATCC BAA-614] Length=388 Score = 718 bits (1853), Expect = 0.0, Method: Compositional matrix adjust. Identities = 363/388 (94%), Positives = 373/388 (97%), Gaps = 1/388 (0%) Query 1 VTVGLGMPQPPAPTLAPRRATRQLMVGNVGVGSDHPVSVQSMCTTKTHDVNSTLQQIAEL 60 +TVGLGMP PAPTLAPRR TRQLMV +VGVGSD+P+SVQSMCTTKTHDVN+TLQQIAEL Sbjct 1 MTVGLGMPDAPAPTLAPRRKTRQLMVRDVGVGSDYPISVQSMCTTKTHDVNTTLQQIAEL 60 Query 61 TAAGCDIVRVACPRQEDADALAEIARHSQIPVVADIHFQPRYIFAAIDAGCAAVRVNPGN 120 TAAGCDIVRVACPRQEDADALAEIARHSQIPV+ADIHFQP+YIFAAIDAGCAAVRVNPGN Sbjct 61 TAAGCDIVRVACPRQEDADALAEIARHSQIPVIADIHFQPKYIFAAIDAGCAAVRVNPGN 120 Query 121 IKEFDGRVGEVAKAAGAAGIPIRIGVNAGSLDKRFMEKYGKATPEALVESALWEASLFEE 180 IKEFDGRVGEVAKAA AAGIPIRIGVNAGSLDKRFMEKYGKATPEALVESALWEASLFEE Sbjct 121 IKEFDGRVGEVAKAAAAAGIPIRIGVNAGSLDKRFMEKYGKATPEALVESALWEASLFEE 180 Query 181 HGFGDIKISVKHNDPVVMVAAYELLAARCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSR 240 HGFGDIKISVKHNDPVVMVAAYE LAA+CDYPLHLGVTEAGPAFQGTIKSAVAFGALLSR Sbjct 181 HGFGDIKISVKHNDPVVMVAAYEQLAAQCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSR 240 Query 241 GIGDTIRVSLSAPPVEEVKVGNQVLESLNLRPRSLEIVSCPSCGRAQVDVYTLANEVTAG 300 GIGDTIRVSLSAPPVEEVKVG Q+LESLNLRPR LEIVSCPSCGRAQVDVYTLAN VTAG Sbjct 241 GIGDTIRVSLSAPPVEEVKVGIQILESLNLRPRGLEIVSCPSCGRAQVDVYTLANAVTAG 300 Query 301 LDGLDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPEAQIVETLIE 360 LDGLDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPEAQIVETLIE Sbjct 301 LDGLDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPEAQIVETLIE 360 Query 361 EAMRLAAEMG-EQDPGATPSGSPIVTVS 387 EAMRLAAEMG + P T SGSPIVTVS Sbjct 361 EAMRLAAEMGIDHGPDTTSSGSPIVTVS 388 >gi|41409036|ref|NP_961872.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Mycobacterium avium subsp. paratuberculosis K-10] gi|50400911|sp|Q73VS3.1|ISPG_MYCPA RecName: Full=4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; AltName: Full=1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase gi|41397395|gb|AAS05255.1| GcpE [Mycobacterium avium subsp. paratuberculosis K-10] gi|336459075|gb|EGO38025.1| 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase [Mycobacterium avium subsp. paratuberculosis S397] Length=388 Score = 713 bits (1841), Expect = 0.0, Method: Compositional matrix adjust. Identities = 359/388 (93%), Positives = 372/388 (96%), Gaps = 1/388 (0%) Query 1 VTVGLGMPQPPAPTLAPRRATRQLMVGNVGVGSDHPVSVQSMCTTKTHDVNSTLQQIAEL 60 +T GLGMPQ PAPTLAPRR TRQLMV +VGVGSD+P+SVQSMCTTKTHDVNSTLQQIAEL Sbjct 1 MTTGLGMPQTPAPTLAPRRRTRQLMVRDVGVGSDYPISVQSMCTTKTHDVNSTLQQIAEL 60 Query 61 TAAGCDIVRVACPRQEDADALAEIARHSQIPVVADIHFQPRYIFAAIDAGCAAVRVNPGN 120 TAAGCDIVRVACPRQEDADALAEIARHSQIPV+ADIHFQP+YIFAAIDAGCAAVRVNPGN Sbjct 61 TAAGCDIVRVACPRQEDADALAEIARHSQIPVIADIHFQPKYIFAAIDAGCAAVRVNPGN 120 Query 121 IKEFDGRVGEVAKAAGAAGIPIRIGVNAGSLDKRFMEKYGKATPEALVESALWEASLFEE 180 IKEFDGRVGEVAKAA AAGIPIRIGVNAGSLDKRFM KYGKATPEALVESALWEASLFEE Sbjct 121 IKEFDGRVGEVAKAAAAAGIPIRIGVNAGSLDKRFMAKYGKATPEALVESALWEASLFEE 180 Query 181 HGFGDIKISVKHNDPVVMVAAYELLAARCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSR 240 HGF DIKISVKHNDPVVMVAAYE LA +CDYPLHLGVTEAGPAFQGTIKSAVAFGALLSR Sbjct 181 HGFSDIKISVKHNDPVVMVAAYEQLAEQCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSR 240 Query 241 GIGDTIRVSLSAPPVEEVKVGNQVLESLNLRPRSLEIVSCPSCGRAQVDVYTLANEVTAG 300 GIGDTIRVSLSAPPVEEVKVG Q+LESLNLRPRSLEIVSCPSCGRAQVDVYTLANEV+AG Sbjct 241 GIGDTIRVSLSAPPVEEVKVGIQILESLNLRPRSLEIVSCPSCGRAQVDVYTLANEVSAG 300 Query 301 LDGLDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPEAQIVETLIE 360 LDGLDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPE+QIVETLIE Sbjct 301 LDGLDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPESQIVETLIE 360 Query 361 EAMRLAAEMG-EQDPGATPSGSPIVTVS 387 EAMR+AA+M E P AT SGSP+VTVS Sbjct 361 EAMRIAAQMNSEGGPEATSSGSPVVTVS 388 >gi|342858280|ref|ZP_08714935.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Mycobacterium colombiense CECT 3035] gi|342133984|gb|EGT87164.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Mycobacterium colombiense CECT 3035] Length=392 Score = 711 bits (1834), Expect = 0.0, Method: Compositional matrix adjust. Identities = 359/392 (92%), Positives = 371/392 (95%), Gaps = 5/392 (1%) Query 1 VTVGLGMPQPPAPTLAPRRATRQLMVGNVGVGSDHPVSVQSMCTTKTHDVNSTLQQIAEL 60 +T GLGMP+ PAPTLAPRR TRQLMV +VGVGSDHP+SVQSMCTTKTHDVN+TLQQIAEL Sbjct 1 MTTGLGMPKTPAPTLAPRRKTRQLMVRDVGVGSDHPISVQSMCTTKTHDVNTTLQQIAEL 60 Query 61 TAAGCDIVRVACPRQEDADALAEIARHSQIPVVADIHFQPRYIFAAIDAGCAAVRVNPGN 120 TAAGCDIVRVACPRQEDADALAEIARHSQIPV+ADIHFQP+YIFAAIDAGCAAVRVNPGN Sbjct 61 TAAGCDIVRVACPRQEDADALAEIARHSQIPVIADIHFQPKYIFAAIDAGCAAVRVNPGN 120 Query 121 IKEFDGRVGEVAKAAGAAGIPIRIGVNAGSLDKRFMEKYGKATPEALVESALWEASLFEE 180 IKEFDGRVGEVAKAA AA IPIRIGVNAGSLDKRFM+KYGKATPEALVESALWEASLFEE Sbjct 121 IKEFDGRVGEVAKAAAAADIPIRIGVNAGSLDKRFMQKYGKATPEALVESALWEASLFEE 180 Query 181 HGFGDIKISVKHNDPVVMVAAYELLAARCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSR 240 HGFG+IKISVKHNDPVVMVAAYE LA +CDYPLHLGVTEAGPAFQGTIKSAVAFGALLSR Sbjct 181 HGFGNIKISVKHNDPVVMVAAYEQLAEQCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSR 240 Query 241 GIGDTIRVSLSAPPVEEVKVGNQVLESLNLRPRSLEIVSCPSCGRAQVDVYTLANEVTAG 300 GIGDTIRVSLSAPPVEEVKVG Q+LESLNLRPR LEIVSCPSCGRAQVDVYTLAN VTAG Sbjct 241 GIGDTIRVSLSAPPVEEVKVGIQILESLNLRPRGLEIVSCPSCGRAQVDVYTLANAVTAG 300 Query 301 LDGLDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPEAQIVETLIE 360 LDGLDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPEAQIVETLIE Sbjct 301 LDGLDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPEAQIVETLIE 360 Query 361 EAMRLAAEMG-----EQDPGATPSGSPIVTVS 387 EA RLAAEMG E P AT SGSP+VTVS Sbjct 361 EAQRLAAEMGHEMNSEDGPEATSSGSPVVTVS 392 >gi|254776154|ref|ZP_05217670.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Mycobacterium avium subsp. avium ATCC 25291] Length=382 Score = 705 bits (1820), Expect = 0.0, Method: Compositional matrix adjust. Identities = 355/382 (93%), Positives = 367/382 (97%), Gaps = 1/382 (0%) Query 7 MPQPPAPTLAPRRATRQLMVGNVGVGSDHPVSVQSMCTTKTHDVNSTLQQIAELTAAGCD 66 MPQ PAPTLAPRR TRQLMV +VGVGSD+P+SVQSMCTTKTHDVNSTLQQIAELTAAGCD Sbjct 1 MPQTPAPTLAPRRRTRQLMVRDVGVGSDYPISVQSMCTTKTHDVNSTLQQIAELTAAGCD 60 Query 67 IVRVACPRQEDADALAEIARHSQIPVVADIHFQPRYIFAAIDAGCAAVRVNPGNIKEFDG 126 IVRVACPRQEDADALAEIARHSQIPV+ADIHFQP+YIFAAIDAGCAAVRVNPGNIKEFDG Sbjct 61 IVRVACPRQEDADALAEIARHSQIPVIADIHFQPKYIFAAIDAGCAAVRVNPGNIKEFDG 120 Query 127 RVGEVAKAAGAAGIPIRIGVNAGSLDKRFMEKYGKATPEALVESALWEASLFEEHGFGDI 186 RVGEVAKAA AAGIPIRIGVNAGSLDKRFM KYGKATPEALVESALWEASLFEEHGF DI Sbjct 121 RVGEVAKAAAAAGIPIRIGVNAGSLDKRFMAKYGKATPEALVESALWEASLFEEHGFSDI 180 Query 187 KISVKHNDPVVMVAAYELLAARCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSRGIGDTI 246 KISVKHNDPVVMVAAYE LA +CDYPLHLGVTEAGPAFQGTIKSAVAFGALLSRGIGDTI Sbjct 181 KISVKHNDPVVMVAAYEQLAEQCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSRGIGDTI 240 Query 247 RVSLSAPPVEEVKVGNQVLESLNLRPRSLEIVSCPSCGRAQVDVYTLANEVTAGLDGLDV 306 RVSLSAPPVEEVKVG Q+LESLNLRPRSLEIVSCPSCGRAQVDVYTLANEV+AGLDGLDV Sbjct 241 RVSLSAPPVEEVKVGIQILESLNLRPRSLEIVSCPSCGRAQVDVYTLANEVSAGLDGLDV 300 Query 307 PLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPEAQIVETLIEEAMRLA 366 PLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPE+QIVETLIEEAMR+A Sbjct 301 PLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPESQIVETLIEEAMRIA 360 Query 367 AEMG-EQDPGATPSGSPIVTVS 387 A+M E P AT SGSP+VTVS Sbjct 361 AQMNSEGGPEATSSGSPVVTVS 382 >gi|118617655|ref|YP_905987.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Mycobacterium ulcerans Agy99] gi|118569765|gb|ABL04516.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, IspG [Mycobacterium ulcerans Agy99] Length=363 Score = 704 bits (1816), Expect = 0.0, Method: Compositional matrix adjust. Identities = 345/363 (96%), Positives = 357/363 (99%), Gaps = 0/363 (0%) Query 25 MVGNVGVGSDHPVSVQSMCTTKTHDVNSTLQQIAELTAAGCDIVRVACPRQEDADALAEI 84 MV +VGVGSD+PVSVQSMCTTKTHDVN+TLQQIAELTAAGCDIVRVACPRQEDADALAEI Sbjct 1 MVRDVGVGSDYPVSVQSMCTTKTHDVNATLQQIAELTAAGCDIVRVACPRQEDADALAEI 60 Query 85 ARHSQIPVVADIHFQPRYIFAAIDAGCAAVRVNPGNIKEFDGRVGEVAKAAGAAGIPIRI 144 ARHSQIPV ADIHFQP+YIFAAIDAGCAAVRVNPGNIKEFDGRVGEVAKAAGAAGIPIRI Sbjct 61 ARHSQIPVAADIHFQPKYIFAAIDAGCAAVRVNPGNIKEFDGRVGEVAKAAGAAGIPIRI 120 Query 145 GVNAGSLDKRFMEKYGKATPEALVESALWEASLFEEHGFGDIKISVKHNDPVVMVAAYEL 204 GVNAGSLDKRFM+KYGKATPEALVESALWEASLFEEHGFG+IKISVKHNDPV+MVAAYE Sbjct 121 GVNAGSLDKRFMQKYGKATPEALVESALWEASLFEEHGFGNIKISVKHNDPVIMVAAYEQ 180 Query 205 LAARCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSRGIGDTIRVSLSAPPVEEVKVGNQV 264 LAA+CDYPLHLGVTEAGPAFQGTIKSAVAFGALLSRGIGDTIRVSLSAPPVEEVKVGNQ+ Sbjct 181 LAAQCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSRGIGDTIRVSLSAPPVEEVKVGNQI 240 Query 265 LESLNLRPRSLEIVSCPSCGRAQVDVYTLANEVTAGLDGLDVPLRVAVMGCVVNGPGEAR 324 LESLNLRPRSLEIVSCPSCGRAQVDVYTLANEVTAGLDGLDVPLRVAVMGCVVNGPGEAR Sbjct 241 LESLNLRPRSLEIVSCPSCGRAQVDVYTLANEVTAGLDGLDVPLRVAVMGCVVNGPGEAR 300 Query 325 EADLGVASGNGKGQIFVRGEVIKTVPEAQIVETLIEEAMRLAAEMGEQDPGATPSGSPIV 384 EADLGVASGNGKGQIFVRGEVIKTVPEAQIVETLIEEAMR+AAEMG +DPG T SG+PIV Sbjct 301 EADLGVASGNGKGQIFVRGEVIKTVPEAQIVETLIEEAMRIAAEMGTEDPGTTSSGAPIV 360 Query 385 TVS 387 TVS Sbjct 361 TVS 363 >gi|254819030|ref|ZP_05224031.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Mycobacterium intracellulare ATCC 13950] Length=382 Score = 698 bits (1801), Expect = 0.0, Method: Compositional matrix adjust. Identities = 354/382 (93%), Positives = 367/382 (97%), Gaps = 1/382 (0%) Query 7 MPQPPAPTLAPRRATRQLMVGNVGVGSDHPVSVQSMCTTKTHDVNSTLQQIAELTAAGCD 66 MP PAPTLAPRR TRQLMV +VGVGSDHP+SVQSMCTTKTHDVN+TLQQIAELTAAGCD Sbjct 1 MPDAPAPTLAPRRKTRQLMVRDVGVGSDHPISVQSMCTTKTHDVNTTLQQIAELTAAGCD 60 Query 67 IVRVACPRQEDADALAEIARHSQIPVVADIHFQPRYIFAAIDAGCAAVRVNPGNIKEFDG 126 IVRVACPRQEDADALAEIARHSQIPV+ADIHFQP+YIFAAIDAGCAAVRVNPGNIKEFDG Sbjct 61 IVRVACPRQEDADALAEIARHSQIPVIADIHFQPKYIFAAIDAGCAAVRVNPGNIKEFDG 120 Query 127 RVGEVAKAAGAAGIPIRIGVNAGSLDKRFMEKYGKATPEALVESALWEASLFEEHGFGDI 186 RVGEVAKAAGAAG+PIRIGVNAGSLDKRF++KYGKATPEALVESALWEASLFEEHGFGDI Sbjct 121 RVGEVAKAAGAAGVPIRIGVNAGSLDKRFLQKYGKATPEALVESALWEASLFEEHGFGDI 180 Query 187 KISVKHNDPVVMVAAYELLAARCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSRGIGDTI 246 KISVKHNDPVVMVAAYE LA RCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSRGIGDTI Sbjct 181 KISVKHNDPVVMVAAYEQLAERCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSRGIGDTI 240 Query 247 RVSLSAPPVEEVKVGNQVLESLNLRPRSLEIVSCPSCGRAQVDVYTLANEVTAGLDGLDV 306 RVSLSAPPVEEVKVG Q+LESLNLRPR LEIVSCPSCGRAQVDVYTLAN V+AGLDGLDV Sbjct 241 RVSLSAPPVEEVKVGIQILESLNLRPRGLEIVSCPSCGRAQVDVYTLANAVSAGLDGLDV 300 Query 307 PLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPEAQIVETLIEEAMRLA 366 PLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPEAQIVETLIEEAMR+A Sbjct 301 PLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPEAQIVETLIEEAMRIA 360 Query 367 AEM-GEQDPGATPSGSPIVTVS 387 AEM G+ P T SGSP+VTVS Sbjct 361 AEMGGDHGPDTTSSGSPVVTVS 382 >gi|54026089|ref|YP_120331.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Nocardia farcinica IFM 10152] gi|73621100|sp|Q5YS74.1|ISPG_NOCFA RecName: Full=4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; AltName: Full=1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase gi|54017597|dbj|BAD58967.1| putative 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase [Nocardia farcinica IFM 10152] Length=385 Score = 697 bits (1798), Expect = 0.0, Method: Compositional matrix adjust. Identities = 342/386 (89%), Positives = 361/386 (94%), Gaps = 4/386 (1%) Query 2 TVGLGMPQPPAPTLAPRRATRQLMVGNVGVGSDHPVSVQSMCTTKTHDVNSTLQQIAELT 61 T+GLGMP PA LAPRR TRQLMVG+VGVGSDHPVSVQSM TTKTHDVN+TLQQIA+LT Sbjct 4 TIGLGMPTAPAAVLAPRRKTRQLMVGSVGVGSDHPVSVQSMTTTKTHDVNATLQQIAQLT 63 Query 62 AAGCDIVRVACPRQEDADALAEIARHSQIPVVADIHFQPRYIFAAIDAGCAAVRVNPGNI 121 A+GCDIVRVACPRQEDADALA IA+ SQIPV+ADIHFQPRYIFAAIDAGCAAVRVNPGNI Sbjct 64 ASGCDIVRVACPRQEDADALATIAKKSQIPVIADIHFQPRYIFAAIDAGCAAVRVNPGNI 123 Query 122 KEFDGRVGEVAKAAGAAGIPIRIGVNAGSLDKRFMEKYGKATPEALVESALWEASLFEEH 181 KEFDGRV EVAKAAGAAGIPIRIGVNAGSLDKR +EKYGKATPEALVESALWEASLFEEH Sbjct 124 KEFDGRVKEVAKAAGAAGIPIRIGVNAGSLDKRMLEKYGKATPEALVESALWEASLFEEH 183 Query 182 GFGDIKISVKHNDPVVMVAAYELLAARCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSRG 241 GFGDIKISVKHNDPV+MV AY LAA+CDYPLHLGVTEAGPAFQGTIKSAVAFGALLS G Sbjct 184 GFGDIKISVKHNDPVIMVEAYRQLAAQCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSEG 243 Query 242 IGDTIRVSLSAPPVEEVKVGNQVLESLNLRPRSLEIVSCPSCGRAQVDVYTLANEVTAGL 301 IGDTIRVSLSAPPVEEVKVG Q+L+SLNLRPR LEIVSCPSCGRAQVDVYTLANEVTAGL Sbjct 244 IGDTIRVSLSAPPVEEVKVGTQILQSLNLRPRKLEIVSCPSCGRAQVDVYTLANEVTAGL 303 Query 302 DGLDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPEAQIVETLIEE 361 +G++VPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFV+G+VIKTVPE QIVETLIEE Sbjct 304 EGMEVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVKGQVIKTVPEHQIVETLIEE 363 Query 362 AMRLAAEMGEQDPGATPSGSPIVTVS 387 AMR+A EMGEQ SG P+VTVS Sbjct 364 AMRIAEEMGEQ----AGSGEPVVTVS 385 >gi|118468236|ref|YP_886917.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Mycobacterium smegmatis str. MC2 155] gi|118169523|gb|ABK70419.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Mycobacterium smegmatis str. MC2 155] Length=388 Score = 694 bits (1792), Expect = 0.0, Method: Compositional matrix adjust. Identities = 350/386 (91%), Positives = 367/386 (96%), Gaps = 0/386 (0%) Query 2 TVGLGMPQPPAPTLAPRRATRQLMVGNVGVGSDHPVSVQSMCTTKTHDVNSTLQQIAELT 61 ++GLGMP PPAPTLAPRR TRQL VG VG+GS+HP++VQSMCTTKTHDVNSTLQQIAELT Sbjct 3 SIGLGMPAPPAPTLAPRRKTRQLNVGGVGIGSEHPIAVQSMCTTKTHDVNSTLQQIAELT 62 Query 62 AAGCDIVRVACPRQEDADALAEIARHSQIPVVADIHFQPRYIFAAIDAGCAAVRVNPGNI 121 A+GCDIVRVACPRQEDADALAEIARHSQIPV+ADIHFQP+YIFAAIDAGCAAVRVNPGNI Sbjct 63 ASGCDIVRVACPRQEDADALAEIARHSQIPVIADIHFQPKYIFAAIDAGCAAVRVNPGNI 122 Query 122 KEFDGRVGEVAKAAGAAGIPIRIGVNAGSLDKRFMEKYGKATPEALVESALWEASLFEEH 181 KEFDGRV EVAKAAG AGIPIRIGVNAGSLDKRF+EKYGKATPEALVESALWEASLFEEH Sbjct 123 KEFDGRVKEVAKAAGDAGIPIRIGVNAGSLDKRFLEKYGKATPEALVESALWEASLFEEH 182 Query 182 GFGDIKISVKHNDPVVMVAAYELLAARCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSRG 241 GFGDIKISVKHNDPV+MVAAYE LAA+CDYPLHLGVTEAGPAFQGTIKSAVAFGALLS+G Sbjct 183 GFGDIKISVKHNDPVIMVAAYEQLAAQCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSKG 242 Query 242 IGDTIRVSLSAPPVEEVKVGNQVLESLNLRPRSLEIVSCPSCGRAQVDVYTLANEVTAGL 301 IGDTIRVSLSAPP EEVKVGNQ+LESLNLRPR LEIVSCPSCGRAQVDVYTLAN VTAGL Sbjct 243 IGDTIRVSLSAPPAEEVKVGNQILESLNLRPRGLEIVSCPSCGRAQVDVYTLANAVTAGL 302 Query 302 DGLDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPEAQIVETLIEE 361 DGLDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFV+GEVIKTVPEAQIVETLIEE Sbjct 303 DGLDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVKGEVIKTVPEAQIVETLIEE 362 Query 362 AMRLAAEMGEQDPGATPSGSPIVTVS 387 AMRLA E+G SGSP+VTVS Sbjct 363 AMRLAEEIGTARGSDDASGSPVVTVS 388 >gi|169630251|ref|YP_001703900.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Mycobacterium abscessus ATCC 19977] gi|169242218|emb|CAM63246.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase(IspG) [Mycobacterium abscessus] Length=395 Score = 689 bits (1779), Expect = 0.0, Method: Compositional matrix adjust. Identities = 344/395 (88%), Positives = 364/395 (93%), Gaps = 8/395 (2%) Query 1 VTVGLGMPQ---PPAPTLAPRRATRQLMVGNVGVGSDHPVSVQSMCTTKTHDVNSTLQQI 57 + GLGMP P PTLAPRR TRQLMVG+VGVGSD PVSVQSMCTTKTHDVNSTLQQI Sbjct 1 MMTGLGMPSLPGAPPPTLAPRRQTRQLMVGSVGVGSDSPVSVQSMCTTKTHDVNSTLQQI 60 Query 58 AELTAAGCDIVRVACPRQEDADALAEIARHSQIPVVADIHFQPRYIFAAIDAGCAAVRVN 117 AELTA+GCDIVRVACPRQEDADALAEIAR S+IPV+ADIHFQP+YIFAAIDAGCAAVRVN Sbjct 61 AELTASGCDIVRVACPRQEDADALAEIARKSKIPVIADIHFQPKYIFAAIDAGCAAVRVN 120 Query 118 PGNIKEFDGRVGEVAKAAGAAGIPIRIGVNAGSLDKRFMEKYGKATPEALVESALWEASL 177 PGNIKEFDGRV EVAKAAG AGIPIRIGVNAGSLD R + KYGKATPEALVESALWEA L Sbjct 121 PGNIKEFDGRVKEVAKAAGDAGIPIRIGVNAGSLDPRILGKYGKATPEALVESALWEAGL 180 Query 178 FEEHGFGDIKISVKHNDPVVMVAAYELLAARCDYPLHLGVTEAGPAFQGTIKSAVAFGAL 237 FEEHGFGDIKISVKHNDPV+MVAAYELLAA+CDYPLHLGVTEAGPAFQGTIKSAVAFGAL Sbjct 181 FEEHGFGDIKISVKHNDPVIMVAAYELLAAQCDYPLHLGVTEAGPAFQGTIKSAVAFGAL 240 Query 238 LSRGIGDTIRVSLSAPPVEEVKVGNQVLESLNLRPRSLEIVSCPSCGRAQVDVYTLANEV 297 LS+GIGDTIRVSLSAPP EEVKVGNQ+LESLNLRPRSLEIVSCPSCGRAQVDVYTLAN V Sbjct 241 LSKGIGDTIRVSLSAPPAEEVKVGNQILESLNLRPRSLEIVSCPSCGRAQVDVYTLANAV 300 Query 298 TAGLDGLDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPEAQIVET 357 +AGL+GLDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFV+GEVIKTVPEA IVET Sbjct 301 SAGLEGLDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVKGEVIKTVPEALIVET 360 Query 358 LIEEAMRLAAEMGEQD-----PGATPSGSPIVTVS 387 LI+EAMRLA +MG ++ TP+G P+VTVS Sbjct 361 LIDEAMRLAEQMGLENGAGIGSDGTPTGQPVVTVS 395 >gi|108799011|ref|YP_639208.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Mycobacterium sp. MCS] gi|119868126|ref|YP_938078.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Mycobacterium sp. KMS] gi|126434614|ref|YP_001070305.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Mycobacterium sp. JLS] gi|108769430|gb|ABG08152.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Mycobacterium sp. MCS] gi|119694215|gb|ABL91288.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Mycobacterium sp. KMS] gi|126234414|gb|ABN97814.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Mycobacterium sp. JLS] Length=393 Score = 687 bits (1774), Expect = 0.0, Method: Compositional matrix adjust. Identities = 345/387 (90%), Positives = 365/387 (95%), Gaps = 2/387 (0%) Query 3 VGLGMPQPPAPTLAPRRATRQLMVGNVGVGSDHPVSVQSMCTTKTHDVNSTLQQIAELTA 62 +GLGMP P P LAPRR TRQLMV +VGVGSDHP+SVQSMCTTKTHD+NSTLQQIAELTA Sbjct 7 IGLGMPPAPPPVLAPRRKTRQLMVRDVGVGSDHPISVQSMCTTKTHDINSTLQQIAELTA 66 Query 63 AGCDIVRVACPRQEDADALAEIARHSQIPVVADIHFQPRYIFAAIDAGCAAVRVNPGNIK 122 +GCDIVRVACPRQEDADAL IA+ S+IPV+ADIHFQP+YIFAAIDAGCAAVRVNPGNIK Sbjct 67 SGCDIVRVACPRQEDADALPIIAKKSKIPVIADIHFQPKYIFAAIDAGCAAVRVNPGNIK 126 Query 123 EFDGRVGEVAKAAGAAGIPIRIGVNAGSLDKRFMEKYGKATPEALVESALWEASLFEEHG 182 EFDGRV EVAKAAG AGIPIRIGVNAGSLDKRF++KYGKATPEALVESALWEASLFEEHG Sbjct 127 EFDGRVKEVAKAAGDAGIPIRIGVNAGSLDKRFLQKYGKATPEALVESALWEASLFEEHG 186 Query 183 FGDIKISVKHNDPVVMVAAYELLAARCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSRGI 242 FGDIKISVKHNDPVVMVAAYELLAAR DYPLHLGVTEAGPAFQGTIKSAVAFGALLS+GI Sbjct 187 FGDIKISVKHNDPVVMVAAYELLAARSDYPLHLGVTEAGPAFQGTIKSAVAFGALLSKGI 246 Query 243 GDTIRVSLSAPPVEEVKVGNQVLESLNLRPRSLEIVSCPSCGRAQVDVYTLANEVTAGLD 302 GDTIRVSLSAPP EEVKVGNQ+LESLNLRPR LEIVSCPSCGRAQVDVYTLANEVTAGL+ Sbjct 247 GDTIRVSLSAPPAEEVKVGNQILESLNLRPRGLEIVSCPSCGRAQVDVYTLANEVTAGLE 306 Query 303 GLDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPEAQIVETLIEEA 362 G+DVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFV+GEVIKTVPEAQIVETLIEEA Sbjct 307 GMDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVKGEVIKTVPEAQIVETLIEEA 366 Query 363 MRLAAEMGE--QDPGATPSGSPIVTVS 387 MR+A E+G P +PSGSP+VTVS Sbjct 367 MRIAEEIGAAGDSPEGSPSGSPVVTVS 393 >gi|15827829|ref|NP_302092.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Mycobacterium leprae TN] gi|221230306|ref|YP_002503722.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Mycobacterium leprae Br4923] gi|18202765|sp|Q9CBU5.1|ISPG_MYCLE RecName: Full=4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; AltName: Full=1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase gi|254806883|sp|B8ZRU5.1|ISPG_MYCLB RecName: Full=4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; AltName: Full=1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase gi|13093381|emb|CAC30532.1| conserved hypothetical protein [Mycobacterium leprae] gi|219933413|emb|CAR71676.1| conserved hypothetical protein [Mycobacterium leprae Br4923] Length=392 Score = 684 bits (1764), Expect = 0.0, Method: Compositional matrix adjust. Identities = 340/388 (88%), Positives = 363/388 (94%), Gaps = 5/388 (1%) Query 5 LGMPQPPAPTLAPRRATRQLMVGNVGVGSDHPVSVQSMCTTKTHDVNSTLQQIAELTAAG 64 LGMP+ PAP LAPRR TRQLMVGNVGVGSDH +SVQSMC TKTHDVN+TLQQIAELT AG Sbjct 5 LGMPEAPAPGLAPRRITRQLMVGNVGVGSDHQISVQSMCITKTHDVNATLQQIAELTTAG 64 Query 65 CDIVRVACPRQEDADALAEIARHSQIPVVADIHFQPRYIFAAIDAGCAAVRVNPGNIKEF 124 CDIVRVACPRQEDADALAEIARHS+IPV+ DIHFQP+YIFAAIDAGCAAVRVNPGNIKEF Sbjct 65 CDIVRVACPRQEDADALAEIARHSKIPVIVDIHFQPKYIFAAIDAGCAAVRVNPGNIKEF 124 Query 125 DGRVGEVAKAAGAAGIPIRIGVNAGSLDKRFMEKYGKATPEALVESALWEASLFEEHGFG 184 DGRVGEVAKAA AAGIPIRIGVNAGSLDKRFM+KYGKAT EALVESALWEASLFEEHGFG Sbjct 125 DGRVGEVAKAAAAAGIPIRIGVNAGSLDKRFMDKYGKATSEALVESALWEASLFEEHGFG 184 Query 185 DIKISVKHNDPVVMVAAYELLAARCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSRGIGD 244 +IKISVKH+DPVVMVAAYE LAA+CDYPLHLGVTEAGP FQGT+KSAVAFGALLS+GIGD Sbjct 185 NIKISVKHHDPVVMVAAYEQLAAQCDYPLHLGVTEAGPVFQGTVKSAVAFGALLSKGIGD 244 Query 245 TIRVSLSAPPVEEVKVGNQVLESLNLRPRSLEIVSCPSCGRAQVDVYTLANEVTAGLDGL 304 TIRVSLSAPPVEE+KVGNQ+LESLNLRPRS EIVSCPSCGRAQVDVY LANEV+AGLDGL Sbjct 245 TIRVSLSAPPVEEIKVGNQILESLNLRPRSHEIVSCPSCGRAQVDVYKLANEVSAGLDGL 304 Query 305 DVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPEAQIVETLIEEAMR 364 +VPLR+AVMGCVVNGPGEAR+ADLGVASGNGKGQIFV+GEVIKTVPEAQIVETLIEEAMR Sbjct 305 EVPLRIAVMGCVVNGPGEARDADLGVASGNGKGQIFVKGEVIKTVPEAQIVETLIEEAMR 364 Query 365 LAAEMGEQDPG-----ATPSGSPIVTVS 387 L +EMG + T SGSP+VTV+ Sbjct 365 LVSEMGTEKGSDHCSETTRSGSPVVTVN 392 >gi|333991228|ref|YP_004523842.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase IspG [Mycobacterium sp. JDM601] gi|333487196|gb|AEF36588.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase IspG [Mycobacterium sp. JDM601] Length=390 Score = 679 bits (1752), Expect = 0.0, Method: Compositional matrix adjust. Identities = 346/390 (89%), Positives = 367/390 (95%), Gaps = 3/390 (0%) Query 1 VTVGLGMPQPPAPTLAPRRATRQLMVGNVGVGSDHPVSVQSMCTTKTHDVNSTLQQIAEL 60 ++VGLGMP PAPTLAPRR TRQLMVG VGVGSDHP+SVQSMCTTKTHDV++TLQQIA L Sbjct 1 MSVGLGMPAVPAPTLAPRRKTRQLMVGGVGVGSDHPISVQSMCTTKTHDVDATLQQIAAL 60 Query 61 TAAGCDIVRVACPRQEDADALAEIARHSQIPVVADIHFQPRYIFAAIDAGCAAVRVNPGN 120 T AGCDIVRVACPRQEDADALA IAR S+IPV+ADIHFQP+YIFAAIDAGCAAVRVNPGN Sbjct 61 TTAGCDIVRVACPRQEDADALATIARKSKIPVIADIHFQPKYIFAAIDAGCAAVRVNPGN 120 Query 121 IKEFDGRVGEVAKAAGAAGIPIRIGVNAGSLDKRFMEKYGKATPEALVESALWEASLFEE 180 IKEFDGRV +VAKAAGAAG+PIRIGVNAGSLDKRF+ KYGKATPEALVESALWEASLFEE Sbjct 121 IKEFDGRVADVAKAAGAAGVPIRIGVNAGSLDKRFLTKYGKATPEALVESALWEASLFEE 180 Query 181 HGFGDIKISVKHNDPVVMVAAYELLAARCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSR 240 HGFGD+KISVKHNDPVVMVAAYE LA +CDYPLHLGVTEAGPAFQGTIKSAVAFGALLSR Sbjct 181 HGFGDVKISVKHNDPVVMVAAYEQLAEQCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSR 240 Query 241 GIGDTIRVSLSAPPVEEVKVGNQVLESLNLRPRSLEIVSCPSCGRAQVDVYTLANEVTAG 300 GIGDTIRVSLSAPPVEEVKVGNQ+LESLNLRPR LEIVSCPSCGRAQVDVY LANEVTAG Sbjct 241 GIGDTIRVSLSAPPVEEVKVGNQILESLNLRPRGLEIVSCPSCGRAQVDVYKLANEVTAG 300 Query 301 LDGLDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPEAQIVETLIE 360 L+GLD+PLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFV+G+VIKTVPEAQIVETLIE Sbjct 301 LEGLDIPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVKGQVIKTVPEAQIVETLIE 360 Query 361 EAMRLAAEMGE--QDPG-ATPSGSPIVTVS 387 EA+RLA+EMG D G TP G+P VTVS Sbjct 361 EALRLASEMGAVGADAGDGTPGGAPTVTVS 390 >gi|120403253|ref|YP_953082.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Mycobacterium vanbaalenii PYR-1] gi|119956071|gb|ABM13076.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Mycobacterium vanbaalenii PYR-1] Length=392 Score = 679 bits (1751), Expect = 0.0, Method: Compositional matrix adjust. Identities = 345/390 (89%), Positives = 367/390 (95%), Gaps = 4/390 (1%) Query 2 TVGLGMPQPPAPTLAPRRATRQLMVGNVGVGSDHPVSVQSMCTTKTHDVNSTLQQIAELT 61 ++GLG+P PPAP LAPRR TRQLMV +VGVGSDHP+SVQSMCTTKTHD+N+TLQQIAELT Sbjct 3 SIGLGIPAPPAPVLAPRRKTRQLMVRDVGVGSDHPISVQSMCTTKTHDINATLQQIAELT 62 Query 62 AAGCDIVRVACPRQEDADALAEIARHSQIPVVADIHFQPRYIFAAIDAGCAAVRVNPGNI 121 A+GCDIVRVACPRQEDADAL IA+ S+IPV+ADIHFQP+YIFAAIDAGCAAVRVNPGNI Sbjct 63 ASGCDIVRVACPRQEDADALPIIAKKSKIPVIADIHFQPKYIFAAIDAGCAAVRVNPGNI 122 Query 122 KEFDGRVGEVAKAAGAAGIPIRIGVNAGSLDKRFMEKYGKATPEALVESALWEASLFEEH 181 KEFDGRV EVAKAAG AGIPIRIGVNAGSLDKRF+EKYGKATPEALVESALWEASLFEEH Sbjct 123 KEFDGRVAEVAKAAGDAGIPIRIGVNAGSLDKRFLEKYGKATPEALVESALWEASLFEEH 182 Query 182 GFGDIKISVKHNDPVVMVAAYELLAARCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSRG 241 GFG+IKISVKHNDPVVMVAAYE LAA+CDYPLHLGVTEAGPAFQGTIKSAVAFGALLS+G Sbjct 183 GFGNIKISVKHNDPVVMVAAYEQLAAQCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSKG 242 Query 242 IGDTIRVSLSAPPVEEVKVGNQVLESLNLRPRSLEIVSCPSCGRAQVDVYTLANEVTAGL 301 IGDTIRVSLSAPP EEVKVGNQ+LESLNLRPR LEIVSCPSCGRAQVDVYTLANEVTAGL Sbjct 243 IGDTIRVSLSAPPAEEVKVGNQILESLNLRPRGLEIVSCPSCGRAQVDVYTLANEVTAGL 302 Query 302 DGLDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPEAQIVETLIEE 361 +G++VPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFV+GEVIKTVPEAQIVETLIEE Sbjct 303 EGMEVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVKGEVIKTVPEAQIVETLIEE 362 Query 362 AMRLAAEMGEQDPGATPS----GSPIVTVS 387 A+RLA EMGE A S GSPIVTVS Sbjct 363 ALRLADEMGEAPGDAQGSEGATGSPIVTVS 392 >gi|226366033|ref|YP_002783816.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Rhodococcus opacus B4] gi|254806887|sp|C1B2V4.1|ISPG_RHOOB RecName: Full=4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; AltName: Full=1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase gi|226244523|dbj|BAH54871.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Rhodococcus opacus B4] Length=385 Score = 675 bits (1742), Expect = 0.0, Method: Compositional matrix adjust. Identities = 331/385 (86%), Positives = 357/385 (93%), Gaps = 4/385 (1%) Query 3 VGLGMPQPPAPTLAPRRATRQLMVGNVGVGSDHPVSVQSMCTTKTHDVNSTLQQIAELTA 62 VGLGMP+ PA LAPRR TRQL VG+VGVGSD PVSVQSMCTTKTHDVN+TLQQIAELTA Sbjct 5 VGLGMPEGPAAVLAPRRKTRQLQVGSVGVGSDFPVSVQSMCTTKTHDVNATLQQIAELTA 64 Query 63 AGCDIVRVACPRQEDADALAEIARHSQIPVVADIHFQPRYIFAAIDAGCAAVRVNPGNIK 122 +GCDIVRVACPRQEDADALA IA+ SQIPV+ADIHFQPRYIFAAI+AGC+AVRVNPGNIK Sbjct 65 SGCDIVRVACPRQEDADALATIAKKSQIPVIADIHFQPRYIFAAIEAGCSAVRVNPGNIK 124 Query 123 EFDGRVGEVAKAAGAAGIPIRIGVNAGSLDKRFMEKYGKATPEALVESALWEASLFEEHG 182 EFDGRV EVAKAAG AGIPIRIGVNAGSLD R M+KYGKATPEALVESALWEA LFEEHG Sbjct 125 EFDGRVKEVAKAAGDAGIPIRIGVNAGSLDPRLMQKYGKATPEALVESALWEAGLFEEHG 184 Query 183 FGDIKISVKHNDPVVMVAAYELLAARCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSRGI 242 FGDIKISVKHNDPV+MV AY LAA+CDYPLHLGVTEAGPAFQGTIKSAVAFGALL+ GI Sbjct 185 FGDIKISVKHNDPVIMVEAYRQLAAQCDYPLHLGVTEAGPAFQGTIKSAVAFGALLAEGI 244 Query 243 GDTIRVSLSAPPVEEVKVGNQVLESLNLRPRSLEIVSCPSCGRAQVDVYTLANEVTAGLD 302 GDTIRVSLSAPP EE+KVG Q+L+SLNLRPR LEIVSCPSCGRAQVDVYTLA+EVTAGL+ Sbjct 245 GDTIRVSLSAPPAEEIKVGTQILQSLNLRPRKLEIVSCPSCGRAQVDVYTLADEVTAGLE 304 Query 303 GLDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPEAQIVETLIEEA 362 G+++PLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFV+G+VIKTVPEAQIVETLIEEA Sbjct 305 GMEIPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVKGKVIKTVPEAQIVETLIEEA 364 Query 363 MRLAAEMGEQDPGATPSGSPIVTVS 387 MR+A EM G + +GSP+VTVS Sbjct 365 MRIAEEM----EGDSTTGSPVVTVS 385 >gi|145224661|ref|YP_001135339.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Mycobacterium gilvum PYR-GCK] gi|315444991|ref|YP_004077870.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Mycobacterium sp. Spyr1] gi|145217147|gb|ABP46551.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Mycobacterium gilvum PYR-GCK] gi|315263294|gb|ADU00036.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Mycobacterium sp. Spyr1] Length=391 Score = 674 bits (1738), Expect = 0.0, Method: Compositional matrix adjust. Identities = 338/385 (88%), Positives = 360/385 (94%), Gaps = 0/385 (0%) Query 3 VGLGMPQPPAPTLAPRRATRQLMVGNVGVGSDHPVSVQSMCTTKTHDVNSTLQQIAELTA 62 VGLGMP PP P LAPRR TRQLMVG+VGVGSDHP++VQSMCTTKTHD+N+TLQQIAELTA Sbjct 7 VGLGMPAPPPPVLAPRRKTRQLMVGDVGVGSDHPIAVQSMCTTKTHDINATLQQIAELTA 66 Query 63 AGCDIVRVACPRQEDADALAEIARHSQIPVVADIHFQPRYIFAAIDAGCAAVRVNPGNIK 122 +GCDIVRVACPRQEDADAL IA+ + IPV+ADIHFQP+YIFAAIDAGCAAVRVNPGNIK Sbjct 67 SGCDIVRVACPRQEDADALPAIAKKANIPVIADIHFQPKYIFAAIDAGCAAVRVNPGNIK 126 Query 123 EFDGRVGEVAKAAGAAGIPIRIGVNAGSLDKRFMEKYGKATPEALVESALWEASLFEEHG 182 EFDGRV EVAKAAG AGIPIRIGVNAGSLD R ++KYGKATPEALVESA+WEASLFEEHG Sbjct 127 EFDGRVKEVAKAAGDAGIPIRIGVNAGSLDPRILKKYGKATPEALVESAMWEASLFEEHG 186 Query 183 FGDIKISVKHNDPVVMVAAYELLAARCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSRGI 242 FGDIKISVKHNDPV+MVAAYE LAA+CDYPLHLGVTEAGPAFQGTIKSAVAFGALLS+GI Sbjct 187 FGDIKISVKHNDPVIMVAAYEQLAAQCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSKGI 246 Query 243 GDTIRVSLSAPPVEEVKVGNQVLESLNLRPRSLEIVSCPSCGRAQVDVYTLANEVTAGLD 302 GDTIRVSLSAPP EEVKVGNQ+LESLNLRPR LEIVSCPSCGRAQVDVYTLANEVTAGL+ Sbjct 247 GDTIRVSLSAPPAEEVKVGNQILESLNLRPRGLEIVSCPSCGRAQVDVYTLANEVTAGLE 306 Query 303 GLDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPEAQIVETLIEEA 362 GL+VPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFV+GEVIKTVPEA IVETLIEEA Sbjct 307 GLEVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVKGEVIKTVPEALIVETLIEEA 366 Query 363 MRLAAEMGEQDPGATPSGSPIVTVS 387 MRLAA+M SGSP+VTVS Sbjct 367 MRLAADMDTTPGSEEASGSPVVTVS 391 >gi|226306041|ref|YP_002766001.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Rhodococcus erythropolis PR4] gi|229491411|ref|ZP_04385235.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Rhodococcus erythropolis SK121] gi|226185158|dbj|BAH33262.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Rhodococcus erythropolis PR4] gi|229321696|gb|EEN87493.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Rhodococcus erythropolis SK121] Length=391 Score = 673 bits (1736), Expect = 0.0, Method: Compositional matrix adjust. Identities = 328/387 (85%), Positives = 354/387 (92%), Gaps = 4/387 (1%) Query 1 VTVGLGMPQPPAPTLAPRRATRQLMVGNVGVGSDHPVSVQSMCTTKTHDVNSTLQQIAEL 60 + +GLGMP PA LAPRR TRQL VG VGVGSD P+SVQSMCTTKTHDVN+TLQQIAEL Sbjct 9 IPIGLGMPSAPAAILAPRRKTRQLQVGTVGVGSDFPISVQSMCTTKTHDVNATLQQIAEL 68 Query 61 TAAGCDIVRVACPRQEDADALAEIARHSQIPVVADIHFQPRYIFAAIDAGCAAVRVNPGN 120 TA+GCDIVRVACPRQEDADAL+ IA+ SQIPV+ADIHFQPRYIFAAIDAGCAAVRVNPGN Sbjct 69 TASGCDIVRVACPRQEDADALSIIAKKSQIPVIADIHFQPRYIFAAIDAGCAAVRVNPGN 128 Query 121 IKEFDGRVGEVAKAAGAAGIPIRIGVNAGSLDKRFMEKYGKATPEALVESALWEASLFEE 180 IKEFDGRV EVAKAAG AGIPIRIGVNAGSLD R MEKYGKATPEALVESALWEA LFEE Sbjct 129 IKEFDGRVKEVAKAAGDAGIPIRIGVNAGSLDPRLMEKYGKATPEALVESALWEAGLFEE 188 Query 181 HGFGDIKISVKHNDPVVMVAAYELLAARCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSR 240 HGFGDIKISVKHNDPV+MV AY LAA+CDYPLHLGVTEAGPAFQGTIKSAVAFGALL+ Sbjct 189 HGFGDIKISVKHNDPVIMVEAYRQLAAKCDYPLHLGVTEAGPAFQGTIKSAVAFGALLAE 248 Query 241 GIGDTIRVSLSAPPVEEVKVGNQVLESLNLRPRSLEIVSCPSCGRAQVDVYTLANEVTAG 300 GIGDTIRVSLSAPP EE+KVGNQ+L+SLNLRPR LEIVSCPSCGRAQVDVYTLA+EV+AG Sbjct 249 GIGDTIRVSLSAPPAEEIKVGNQILQSLNLRPRKLEIVSCPSCGRAQVDVYTLADEVSAG 308 Query 301 LDGLDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPEAQIVETLIE 360 L+G+++PLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFV+G+VIKTVPEAQIVETLIE Sbjct 309 LEGMEIPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVKGKVIKTVPEAQIVETLIE 368 Query 361 EAMRLAAEMGEQDPGATPSGSPIVTVS 387 EAM++A M G G+P+VTVS Sbjct 369 EAMKIAESM----EGDASEGAPVVTVS 391 >gi|118463746|ref|YP_882900.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Mycobacterium avium 104] gi|118165033|gb|ABK65930.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Mycobacterium avium 104] Length=364 Score = 672 bits (1735), Expect = 0.0, Method: Compositional matrix adjust. Identities = 339/364 (94%), Positives = 351/364 (97%), Gaps = 1/364 (0%) Query 25 MVGNVGVGSDHPVSVQSMCTTKTHDVNSTLQQIAELTAAGCDIVRVACPRQEDADALAEI 84 MV +VGVGSD+P+SVQSMCTTKTHDVNSTLQQIAELTAAGCDIVRVACPRQEDADALAEI Sbjct 1 MVRDVGVGSDYPISVQSMCTTKTHDVNSTLQQIAELTAAGCDIVRVACPRQEDADALAEI 60 Query 85 ARHSQIPVVADIHFQPRYIFAAIDAGCAAVRVNPGNIKEFDGRVGEVAKAAGAAGIPIRI 144 ARHSQIPV+ADIHFQP+YIFAAIDAGCAAVRVNPGNIKEFDGRVGEVAKAA AAGIPIRI Sbjct 61 ARHSQIPVIADIHFQPKYIFAAIDAGCAAVRVNPGNIKEFDGRVGEVAKAAAAAGIPIRI 120 Query 145 GVNAGSLDKRFMEKYGKATPEALVESALWEASLFEEHGFGDIKISVKHNDPVVMVAAYEL 204 GVNAGSLDKRFM KYGKATPEALVESALWEASLFEEHGF DIKISVKHNDPVVMVAAYE Sbjct 121 GVNAGSLDKRFMAKYGKATPEALVESALWEASLFEEHGFSDIKISVKHNDPVVMVAAYEQ 180 Query 205 LAARCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSRGIGDTIRVSLSAPPVEEVKVGNQV 264 LA +CDYPLHLGVTEAGPAFQGTIKSAVAFGALLSRGIGDTIRVSLSAPPVEEVKVG Q+ Sbjct 181 LAEQCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSRGIGDTIRVSLSAPPVEEVKVGIQI 240 Query 265 LESLNLRPRSLEIVSCPSCGRAQVDVYTLANEVTAGLDGLDVPLRVAVMGCVVNGPGEAR 324 LESLNLRPRSLEIVSCPSCGRAQVDVYTLANEV+AGLDGLDVPLRVAVMGCVVNGPGEAR Sbjct 241 LESLNLRPRSLEIVSCPSCGRAQVDVYTLANEVSAGLDGLDVPLRVAVMGCVVNGPGEAR 300 Query 325 EADLGVASGNGKGQIFVRGEVIKTVPEAQIVETLIEEAMRLAAEMG-EQDPGATPSGSPI 383 EADLGVASGNGKGQIFVRGEVIKTVPE+QIVETLIEEAMR+AA+M E P AT SGSP+ Sbjct 301 EADLGVASGNGKGQIFVRGEVIKTVPESQIVETLIEEAMRIAAQMNSEGGPEATSSGSPV 360 Query 384 VTVS 387 VTVS Sbjct 361 VTVS 364 >gi|325673446|ref|ZP_08153137.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Rhodococcus equi ATCC 33707] gi|325555467|gb|EGD25138.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Rhodococcus equi ATCC 33707] Length=387 Score = 671 bits (1731), Expect = 0.0, Method: Compositional matrix adjust. Identities = 327/365 (90%), Positives = 346/365 (95%), Gaps = 2/365 (0%) Query 3 VGLGMPQPPA--PTLAPRRATRQLMVGNVGVGSDHPVSVQSMCTTKTHDVNSTLQQIAEL 60 VGLGMP P+ P LAPRR TRQLMVGNVGVGSDHPVSVQSMCTTKTHD+N+TLQQIAEL Sbjct 5 VGLGMPGAPSDIPVLAPRRKTRQLMVGNVGVGSDHPVSVQSMCTTKTHDINATLQQIAEL 64 Query 61 TAAGCDIVRVACPRQEDADALAEIARHSQIPVVADIHFQPRYIFAAIDAGCAAVRVNPGN 120 TA+GCDIVRVACPRQEDADALA IA+ SQIPV+ADIHFQPRYIFAAIDAGCAAVRVNPGN Sbjct 65 TASGCDIVRVACPRQEDADALAAIAKKSQIPVIADIHFQPRYIFAAIDAGCAAVRVNPGN 124 Query 121 IKEFDGRVGEVAKAAGAAGIPIRIGVNAGSLDKRFMEKYGKATPEALVESALWEASLFEE 180 IKEFDGRV EVAKAAG AGIPIRIGVNAGSLD R M+KYGKATPEALVESALWEASLFEE Sbjct 125 IKEFDGRVKEVAKAAGDAGIPIRIGVNAGSLDPRLMQKYGKATPEALVESALWEASLFEE 184 Query 181 HGFGDIKISVKHNDPVVMVAAYELLAARCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSR 240 HGFGDIKISVKHNDPV+MV AY LAA+CDYPLHLGVTEAGPAFQGTIKSAVAFG+LLS Sbjct 185 HGFGDIKISVKHNDPVIMVEAYRQLAAQCDYPLHLGVTEAGPAFQGTIKSAVAFGSLLSE 244 Query 241 GIGDTIRVSLSAPPVEEVKVGNQVLESLNLRPRSLEIVSCPSCGRAQVDVYTLANEVTAG 300 GIGDTIRVSLSAPP EE+KVG Q+L+SLNLRPR LEIVSCPSCGRAQVDVYTLANEVTAG Sbjct 245 GIGDTIRVSLSAPPAEEIKVGTQILQSLNLRPRKLEIVSCPSCGRAQVDVYTLANEVTAG 304 Query 301 LDGLDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPEAQIVETLIE 360 L+G++VPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFV+G+VIKTVPEAQIVETLIE Sbjct 305 LEGMEVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVKGKVIKTVPEAQIVETLIE 364 Query 361 EAMRL 365 EAMR+ Sbjct 365 EAMRI 369 >gi|262202053|ref|YP_003273261.1| 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase [Gordonia bronchialis DSM 43247] gi|262085400|gb|ACY21368.1| 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase [Gordonia bronchialis DSM 43247] Length=394 Score = 671 bits (1731), Expect = 0.0, Method: Compositional matrix adjust. Identities = 328/387 (85%), Positives = 358/387 (93%), Gaps = 1/387 (0%) Query 1 VTVGLGMPQPPAPTLAPRRATRQLMVGNVGVGSDHPVSVQSMCTTKTHDVNSTLQQIAEL 60 V +GLGMP P P LAPRR TRQ+ VG+VGVGSDHP+SVQSM TTKTHD+N+TLQQIAEL Sbjct 9 VPIGLGMPAGPPPVLAPRRTTRQIQVGSVGVGSDHPISVQSMTTTKTHDINATLQQIAEL 68 Query 61 TAAGCDIVRVACPRQEDADALAEIARHSQIPVVADIHFQPRYIFAAIDAGCAAVRVNPGN 120 TA+GCDIVRVACPRQEDADAL IA+ S+IPV+ADIHFQP+YIFAAIDAGCAAVRVNPGN Sbjct 69 TASGCDIVRVACPRQEDADALPIIAKKSKIPVIADIHFQPKYIFAAIDAGCAAVRVNPGN 128 Query 121 IKEFDGRVGEVAKAAGAAGIPIRIGVNAGSLDKRFMEKYGKATPEALVESALWEASLFEE 180 IKEFDGRV EVAKAAG AGIPIRIGVNAGSLDKR M+KYGKATPEALVESALWEASLFEE Sbjct 129 IKEFDGRVKEVAKAAGDAGIPIRIGVNAGSLDKRLMQKYGKATPEALVESALWEASLFEE 188 Query 181 HGFGDIKISVKHNDPVVMVAAYELLAARCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSR 240 HGFGDIKISVKHNDPV+MV AY LAA+CDYPLHLGVTEAGPAFQGTIKS+VAFGALLS+ Sbjct 189 HGFGDIKISVKHNDPVIMVEAYRQLAAQCDYPLHLGVTEAGPAFQGTIKSSVAFGALLSQ 248 Query 241 GIGDTIRVSLSAPPVEEVKVGNQVLESLNLRPRSLEIVSCPSCGRAQVDVYTLANEVTAG 300 GIGDTIRVSLSAPP EE+KVG+ +L+SLNLRPR LEIVSCPSCGRAQVDVY LA+ VTAG Sbjct 249 GIGDTIRVSLSAPPAEEIKVGDAILQSLNLRPRKLEIVSCPSCGRAQVDVYKLADAVTAG 308 Query 301 LDGLDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPEAQIVETLIE 360 L+G++VPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFV+GEVIKTVPEA+IVETLIE Sbjct 309 LEGMEVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVKGEVIKTVPEAEIVETLIE 368 Query 361 EAMRLAAEMGEQDPGATPSGSPIVTVS 387 EA+R+AAE GE G+ GSP+VTVS Sbjct 369 EALRIAAESGETGDGSQ-VGSPVVTVS 394 >gi|312139249|ref|YP_004006585.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase ispg [Rhodococcus equi 103S] gi|311888588|emb|CBH47900.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase IspG [Rhodococcus equi 103S] Length=387 Score = 670 bits (1728), Expect = 0.0, Method: Compositional matrix adjust. Identities = 326/365 (90%), Positives = 346/365 (95%), Gaps = 2/365 (0%) Query 3 VGLGMPQPPA--PTLAPRRATRQLMVGNVGVGSDHPVSVQSMCTTKTHDVNSTLQQIAEL 60 VGLGMP P+ P LAPRR TRQLMVGNVGVGSDHPVSVQSMCTTKTHD+N+TLQQIAEL Sbjct 5 VGLGMPGAPSDIPVLAPRRKTRQLMVGNVGVGSDHPVSVQSMCTTKTHDINATLQQIAEL 64 Query 61 TAAGCDIVRVACPRQEDADALAEIARHSQIPVVADIHFQPRYIFAAIDAGCAAVRVNPGN 120 TA+GCDIVRVACPRQEDADAL+ IA+ SQIPV+ADIHFQPRYIFAAIDAGCAAVRVNPGN Sbjct 65 TASGCDIVRVACPRQEDADALSAIAKKSQIPVIADIHFQPRYIFAAIDAGCAAVRVNPGN 124 Query 121 IKEFDGRVGEVAKAAGAAGIPIRIGVNAGSLDKRFMEKYGKATPEALVESALWEASLFEE 180 IKEFDGRV EVAKAAG AGIPIRIGVNAGSLD R M+KYGKATPEALVESALWEASLFEE Sbjct 125 IKEFDGRVKEVAKAAGDAGIPIRIGVNAGSLDPRLMQKYGKATPEALVESALWEASLFEE 184 Query 181 HGFGDIKISVKHNDPVVMVAAYELLAARCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSR 240 HGFGDIKISVKHNDPV+MV AY LAA+CDYPLHLGVTEAGPAFQGTIKSAVAFG+LLS Sbjct 185 HGFGDIKISVKHNDPVIMVEAYRQLAAQCDYPLHLGVTEAGPAFQGTIKSAVAFGSLLSE 244 Query 241 GIGDTIRVSLSAPPVEEVKVGNQVLESLNLRPRSLEIVSCPSCGRAQVDVYTLANEVTAG 300 GIGDTIRVSLSAPP EE+KVG Q+L+SLNLRPR LEIVSCPSCGRAQVDVYTLANEVTAG Sbjct 245 GIGDTIRVSLSAPPAEEIKVGTQILQSLNLRPRKLEIVSCPSCGRAQVDVYTLANEVTAG 304 Query 301 LDGLDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPEAQIVETLIE 360 L+G++VPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFV+G+VIKTVPEAQIVETLIE Sbjct 305 LEGMEVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVKGKVIKTVPEAQIVETLIE 364 Query 361 EAMRL 365 EAMR+ Sbjct 365 EAMRI 369 >gi|333919260|ref|YP_004492841.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Amycolicicoccus subflavus DQS3-9A1] gi|333481481|gb|AEF40041.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Amycolicicoccus subflavus DQS3-9A1] Length=404 Score = 668 bits (1723), Expect = 0.0, Method: Compositional matrix adjust. Identities = 329/386 (86%), Positives = 355/386 (92%), Gaps = 3/386 (0%) Query 2 TVGLGMPQPPAPTLAPRRATRQLMVGNVGVGSDHPVSVQSMCTTKTHDVNSTLQQIAELT 61 +VGLG+P PAPTLAPRR TRQLMVG+VGVGSD+PVSVQSM TTKTHD+N+TLQQIAELT Sbjct 22 SVGLGIPAGPAPTLAPRRKTRQLMVGDVGVGSDYPVSVQSMTTTKTHDINATLQQIAELT 81 Query 62 AAGCDIVRVACPRQEDADALAEIARHSQIPVVADIHFQPRYIFAAIDAGCAAVRVNPGNI 121 A+GCDIVRVACPRQEDADALA IA+ SQIPV+ADIHFQPRYIFAAI+AGCAAVRVNPGNI Sbjct 82 ASGCDIVRVACPRQEDADALATIAKKSQIPVIADIHFQPRYIFAAIEAGCAAVRVNPGNI 141 Query 122 KEFDGRVGEVAKAAGAAGIPIRIGVNAGSLDKRFMEKYGKATPEALVESALWEASLFEEH 181 +EFDGRV EVAKAA A PIRIGVNAGSLD R + KYGK T EALVESALWEASLFEEH Sbjct 142 REFDGRVQEVAKAAAEANTPIRIGVNAGSLDPRLLAKYGKPTAEALVESALWEASLFEEH 201 Query 182 GFGDIKISVKHNDPVVMVAAYELLAARCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSRG 241 GFGD KISVKHNDPVVMV AYELLA + DYPLHLGVTEAGP+FQGTIKSAVAFGALLS+G Sbjct 202 GFGDFKISVKHNDPVVMVRAYELLAEQSDYPLHLGVTEAGPSFQGTIKSAVAFGALLSKG 261 Query 242 IGDTIRVSLSAPPVEEVKVGNQVLESLNLRPRSLEIVSCPSCGRAQVDVYTLANEVTAGL 301 IGDTIRVSLSAPP EEVKVG+Q+L+SLNLRPR LEIVSCPSCGRAQVDVYTLANEVTAGL Sbjct 262 IGDTIRVSLSAPPAEEVKVGHQILQSLNLRPRKLEIVSCPSCGRAQVDVYTLANEVTAGL 321 Query 302 DGLDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPEAQIVETLIEE 361 +G++VPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFV+G+VIKTVPEAQIVETLIEE Sbjct 322 EGMEVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVKGKVIKTVPEAQIVETLIEE 381 Query 362 AMRLAAEMGEQDPGATPSGSPIVTVS 387 AMR+A EM GA G+P+VTVS Sbjct 382 AMRIAEEMESDGEGA---GAPVVTVS 404 >gi|111023549|ref|YP_706521.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Rhodococcus jostii RHA1] gi|110823079|gb|ABG98363.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Rhodococcus jostii RHA1] Length=377 Score = 667 bits (1720), Expect = 0.0, Method: Compositional matrix adjust. Identities = 328/381 (87%), Positives = 351/381 (93%), Gaps = 4/381 (1%) Query 7 MPQPPAPTLAPRRATRQLMVGNVGVGSDHPVSVQSMCTTKTHDVNSTLQQIAELTAAGCD 66 MP+ PA LAPRR TRQL VG VGVGSD PVSVQSMCTTKTHDVN+TLQQIAELTA+GCD Sbjct 1 MPEGPAAVLAPRRKTRQLQVGTVGVGSDFPVSVQSMCTTKTHDVNATLQQIAELTASGCD 60 Query 67 IVRVACPRQEDADALAEIARHSQIPVVADIHFQPRYIFAAIDAGCAAVRVNPGNIKEFDG 126 IVRVACPRQEDADALA IA+ SQIPV+ADIHFQPRYIFAAI+AGCAAVRVNPGNIKEFDG Sbjct 61 IVRVACPRQEDADALATIAKKSQIPVIADIHFQPRYIFAAIEAGCAAVRVNPGNIKEFDG 120 Query 127 RVGEVAKAAGAAGIPIRIGVNAGSLDKRFMEKYGKATPEALVESALWEASLFEEHGFGDI 186 RV EVAKAAG AGIPIRIGVNAGSLD R M+KYGKATPEALVESALWEA LFEEHGFGDI Sbjct 121 RVKEVAKAAGDAGIPIRIGVNAGSLDPRLMQKYGKATPEALVESALWEAGLFEEHGFGDI 180 Query 187 KISVKHNDPVVMVAAYELLAARCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSRGIGDTI 246 KISVKHNDPV+MV AY LAA+C+YPLHLGVTEAGPAFQGTIKSAVAFGALL+ GIGDTI Sbjct 181 KISVKHNDPVIMVEAYRQLAAQCNYPLHLGVTEAGPAFQGTIKSAVAFGALLADGIGDTI 240 Query 247 RVSLSAPPVEEVKVGNQVLESLNLRPRSLEIVSCPSCGRAQVDVYTLANEVTAGLDGLDV 306 RVSLSAPP EE+KVG Q+L+SLNLRPR LEIVSCPSCGRAQVDVYTLA+EVTAGL+G+++ Sbjct 241 RVSLSAPPAEEIKVGTQILQSLNLRPRKLEIVSCPSCGRAQVDVYTLADEVTAGLEGMEI 300 Query 307 PLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPEAQIVETLIEEAMRLA 366 PLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFV+G+VIKTVPEAQIVETLIEEAMR+A Sbjct 301 PLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVKGKVIKTVPEAQIVETLIEEAMRIA 360 Query 367 AEMGEQDPGATPSGSPIVTVS 387 EM G SGSP+VTVS Sbjct 361 EEM----EGDATSGSPVVTVS 377 >gi|326382910|ref|ZP_08204600.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Gordonia neofelifaecis NRRL B-59395] gi|326198500|gb|EGD55684.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Gordonia neofelifaecis NRRL B-59395] Length=384 Score = 666 bits (1719), Expect = 0.0, Method: Compositional matrix adjust. Identities = 327/386 (85%), Positives = 354/386 (92%), Gaps = 5/386 (1%) Query 2 TVGLGMPQPPAPTLAPRRATRQLMVGNVGVGSDHPVSVQSMCTTKTHDVNSTLQQIAELT 61 ++GLG+P P P LAPRR TRQ+ VG+VGVGSD P+SVQSMCTTKTHDVN+TLQQIA+LT Sbjct 4 SIGLGIPSGPPPVLAPRRKTRQIRVGDVGVGSDFPISVQSMCTTKTHDVNATLQQIAQLT 63 Query 62 AAGCDIVRVACPRQEDADALAEIARHSQIPVVADIHFQPRYIFAAIDAGCAAVRVNPGNI 121 A+GCDIVRVACPRQEDADAL IAR SQIPV+ADIHFQP+YIFAAIDAGCAAVRVNPGNI Sbjct 64 ASGCDIVRVACPRQEDADALPIIARKSQIPVIADIHFQPKYIFAAIDAGCAAVRVNPGNI 123 Query 122 KEFDGRVGEVAKAAGAAGIPIRIGVNAGSLDKRFMEKYGKATPEALVESALWEASLFEEH 181 KEFDGRV EVAKAAG AGIPIRIGVNAGSLDKR MEKYGKATPEALVESALWEASLFEEH Sbjct 124 KEFDGRVKEVAKAAGDAGIPIRIGVNAGSLDKRLMEKYGKATPEALVESALWEASLFEEH 183 Query 182 GFGDIKISVKHNDPVVMVAAYELLAARCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSRG 241 GFGDIKISVKHNDPVVMV AY LAA+CDYPLHLGVTEAGPAFQGTIKSAVAFGALLS G Sbjct 184 GFGDIKISVKHNDPVVMVEAYRQLAAQCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSEG 243 Query 242 IGDTIRVSLSAPPVEEVKVGNQVLESLNLRPRSLEIVSCPSCGRAQVDVYTLANEVTAGL 301 IGDTIRVSLSAPP EE+KVG+ +L+SLNLRPR LEIVSCPSCGRAQVDVY LA EV+AGL Sbjct 244 IGDTIRVSLSAPPAEEIKVGDAILQSLNLRPRKLEIVSCPSCGRAQVDVYKLAEEVSAGL 303 Query 302 DGLDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPEAQIVETLIEE 361 +G+++PLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFV+GEVIKTVPEAQIVETLI E Sbjct 304 EGMEIPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVKGEVIKTVPEAQIVETLITE 363 Query 362 AMRLAAEMGEQDPGATPSGSPIVTVS 387 A+R+A E GE T G+P+V+VS Sbjct 364 ALRIAEESGE-----TGGGAPVVSVS 384 >gi|343926738|ref|ZP_08766235.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Gordonia alkanivorans NBRC 16433] gi|343763337|dbj|GAA13161.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Gordonia alkanivorans NBRC 16433] Length=395 Score = 665 bits (1717), Expect = 0.0, Method: Compositional matrix adjust. Identities = 328/387 (85%), Positives = 355/387 (92%), Gaps = 1/387 (0%) Query 1 VTVGLGMPQPPAPTLAPRRATRQLMVGNVGVGSDHPVSVQSMCTTKTHDVNSTLQQIAEL 60 V +GLGMP P P LAPRR TRQL VG+VGVGSDHP+SVQSM TTKTHD+N+TLQQIAEL Sbjct 10 VPIGLGMPAGPPPVLAPRRKTRQLFVGSVGVGSDHPISVQSMTTTKTHDINATLQQIAEL 69 Query 61 TAAGCDIVRVACPRQEDADALAEIARHSQIPVVADIHFQPRYIFAAIDAGCAAVRVNPGN 120 TA+GCDIVRVACPR EDA+AL IA+ S+IPV+ADIHFQP+YIFAAIDAGCAAVRVNPGN Sbjct 70 TASGCDIVRVACPRPEDAEALPIIAKKSKIPVIADIHFQPKYIFAAIDAGCAAVRVNPGN 129 Query 121 IKEFDGRVGEVAKAAGAAGIPIRIGVNAGSLDKRFMEKYGKATPEALVESALWEASLFEE 180 IKEFDGRV EVAKAAG AGIPIRIGVNAGSLDKR ++KYGKATPEALVESALWEA LFEE Sbjct 130 IKEFDGRVKEVAKAAGDAGIPIRIGVNAGSLDKRILQKYGKATPEALVESALWEAGLFEE 189 Query 181 HGFGDIKISVKHNDPVVMVAAYELLAARCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSR 240 HGFGDIKISVKHNDPV+MV AY LAA+CDYPLHLGVTEAGPAFQGTIKSAVAFGALLS Sbjct 190 HGFGDIKISVKHNDPVIMVEAYRQLAAQCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSE 249 Query 241 GIGDTIRVSLSAPPVEEVKVGNQVLESLNLRPRSLEIVSCPSCGRAQVDVYTLANEVTAG 300 GIGDTIRVSLSAPP EE+KVG+Q+L+SLNLRPR LEIVSCPSCGRAQVDVY LA+EVTAG Sbjct 250 GIGDTIRVSLSAPPAEEIKVGDQILQSLNLRPRKLEIVSCPSCGRAQVDVYKLADEVTAG 309 Query 301 LDGLDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPEAQIVETLIE 360 L+G++VPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFV+GEVIKTVPEAQIVETLIE Sbjct 310 LEGMEVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVKGEVIKTVPEAQIVETLIE 369 Query 361 EAMRLAAEMGEQDPGATPSGSPIVTVS 387 EA+R+A E GE G T G P+VTVS Sbjct 370 EALRIAEESGETGDG-THVGPPVVTVS 395 >gi|319948048|ref|ZP_08022222.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Dietzia cinnamea P4] gi|319438287|gb|EFV93233.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Dietzia cinnamea P4] Length=394 Score = 657 bits (1696), Expect = 0.0, Method: Compositional matrix adjust. Identities = 327/387 (85%), Positives = 346/387 (90%), Gaps = 0/387 (0%) Query 1 VTVGLGMPQPPAPTLAPRRATRQLMVGNVGVGSDHPVSVQSMCTTKTHDVNSTLQQIAEL 60 + VGLGMP P P LAPRR TRQL VG VGVGSDHPVSVQSM TKTHD+NSTLQQIAEL Sbjct 7 IPVGLGMPDAPPPVLAPRRRTRQLYVGPVGVGSDHPVSVQSMTNTKTHDINSTLQQIAEL 66 Query 61 TAAGCDIVRVACPRQEDADALAEIARHSQIPVVADIHFQPRYIFAAIDAGCAAVRVNPGN 120 TA+GCDIVRVACPRQEDADAL+ IAR S IPV+ADIHFQPRYIFAAIDAGCAAVRVNPGN Sbjct 67 TASGCDIVRVACPRQEDADALSTIARKSPIPVIADIHFQPRYIFAAIDAGCAAVRVNPGN 126 Query 121 IKEFDGRVGEVAKAAGAAGIPIRIGVNAGSLDKRFMEKYGKATPEALVESALWEASLFEE 180 IKEFDGRV EVAKAAG AGIPIRIGVNAGSLD R + KYGKATPEALVESA+WEASLFEE Sbjct 127 IKEFDGRVKEVAKAAGDAGIPIRIGVNAGSLDPRLLAKYGKATPEALVESAVWEASLFEE 186 Query 181 HGFGDIKISVKHNDPVVMVAAYELLAARCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSR 240 HGFGDIKISVKHNDPV+MV AY LAA+ DYPLHLGVTEAGPAFQGTIKSAVAFGALL+ Sbjct 187 HGFGDIKISVKHNDPVIMVEAYRQLAAQTDYPLHLGVTEAGPAFQGTIKSAVAFGALLAE 246 Query 241 GIGDTIRVSLSAPPVEEVKVGNQVLESLNLRPRSLEIVSCPSCGRAQVDVYTLANEVTAG 300 GIGDTIRVSLSAPP EE+KVG Q+L+SLNLRPR LEIVSCPSCGRAQVDVY LA EVTAG Sbjct 247 GIGDTIRVSLSAPPAEEIKVGAQILQSLNLRPRKLEIVSCPSCGRAQVDVYKLAEEVTAG 306 Query 301 LDGLDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPEAQIVETLIE 360 L+G+ VPLRVAVMGCVVNGPGEAR+ADLGVASGNGKGQIFV+GEVIKTVPEA IVETLIE Sbjct 307 LEGMSVPLRVAVMGCVVNGPGEARDADLGVASGNGKGQIFVKGEVIKTVPEAAIVETLIE 366 Query 361 EAMRLAAEMGEQDPGATPSGSPIVTVS 387 EAMR+A EMGE AT P V V+ Sbjct 367 EAMRIADEMGETVGEATEGQGPQVKVT 393 >gi|296139399|ref|YP_003646642.1| 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase [Tsukamurella paurometabola DSM 20162] gi|296027533|gb|ADG78303.1| 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase [Tsukamurella paurometabola DSM 20162] Length=383 Score = 654 bits (1688), Expect = 0.0, Method: Compositional matrix adjust. Identities = 330/387 (86%), Positives = 358/387 (93%), Gaps = 4/387 (1%) Query 1 VTVGLGMPQPPAPTLAPRRATRQLMVGNVGVGSDHPVSVQSMCTTKTHDVNSTLQQIAEL 60 ++VGLGMP PAPTLAPRR TRQL VG VGVGSD P+SVQSMCTTKTHDVN+TLQQIAEL Sbjct 1 MSVGLGMPAAPAPTLAPRRTTRQLNVGGVGVGSDSPISVQSMCTTKTHDVNATLQQIAEL 60 Query 61 TAAGCDIVRVACPRQEDADALAEIARHSQIPVVADIHFQPRYIFAAIDAGCAAVRVNPGN 120 TA+GCDIVRVACPRQEDADAL IA+ + IPV+ADIHFQP+YIFAAIDAGCAAVRVNPGN Sbjct 61 TASGCDIVRVACPRQEDADALPIIAKKANIPVIADIHFQPKYIFAAIDAGCAAVRVNPGN 120 Query 121 IKEFDGRVGEVAKAAGAAGIPIRIGVNAGSLDKRFMEKYGKATPEALVESALWEASLFEE 180 IKEFDGRV EVAKAAG AGIPIRIGVNAGSLDKR MEKYGKATPEALVESALWEASLFEE Sbjct 121 IKEFDGRVKEVAKAAGDAGIPIRIGVNAGSLDKRMMEKYGKATPEALVESALWEASLFEE 180 Query 181 HGFGDIKISVKHNDPVVMVAAYELLAARCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSR 240 HGFGDIKISVKHNDPV+MV AY LAA+CDYPLHLGVTEAGPAFQGTIKS+VAFGALL+ Sbjct 181 HGFGDIKISVKHNDPVIMVEAYRQLAAQCDYPLHLGVTEAGPAFQGTIKSSVAFGALLAE 240 Query 241 GIGDTIRVSLSAPPVEEVKVGNQVLESLNLRPRSLEIVSCPSCGRAQVDVYTLANEVTAG 300 GIGDTIRVSLSAPP EE+KVG+ +L+SLNLRPR LEIVSCPSCGRAQVDVY LANEVTAG Sbjct 241 GIGDTIRVSLSAPPAEEIKVGDAILQSLNLRPRKLEIVSCPSCGRAQVDVYKLANEVTAG 300 Query 301 LDGLDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPEAQIVETLIE 360 L+G++VPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFV+GEVIKTVPEAQIVETLIE Sbjct 301 LEGMEVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVKGEVIKTVPEAQIVETLIE 360 Query 361 EAMRLAAEMGEQDPGATPSGSPIVTVS 387 EA+R+A E G+ + +G+P+VTVS Sbjct 361 EALRIAEESGDSE----GTGAPVVTVS 383 >gi|284992357|ref|YP_003410911.1| 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase [Geodermatophilus obscurus DSM 43160] gi|284065602|gb|ADB76540.1| 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase [Geodermatophilus obscurus DSM 43160] Length=387 Score = 649 bits (1675), Expect = 0.0, Method: Compositional matrix adjust. Identities = 324/387 (84%), Positives = 351/387 (91%), Gaps = 2/387 (0%) Query 1 VTVGLGMPQPPAPTLAPRRATRQLMVGNVGVGSDHPVSVQSMCTTKTHDVNSTLQQIAEL 60 + VGLGMP+ P P LAPRR TRQLMVG+VGVGSDHPVSVQSM TTKT D+N+TLQQIAEL Sbjct 3 IPVGLGMPEVPPPVLAPRRKTRQLMVGDVGVGSDHPVSVQSMTTTKTADINATLQQIAEL 62 Query 61 TAAGCDIVRVACPRQEDADALAEIARHSQIPVVADIHFQPRYIFAAIDAGCAAVRVNPGN 120 TA+GC IVRVA P +DA+AL IAR SQIPV+ADIHFQPRY+FAAIDAGCAAVRVNPGN Sbjct 63 TASGCQIVRVAVPDTDDAEALPIIARKSQIPVIADIHFQPRYVFAAIDAGCAAVRVNPGN 122 Query 121 IKEFDGRVGEVAKAAGAAGIPIRIGVNAGSLDKRFMEKYGKATPEALVESALWEASLFEE 180 IK+FD +VGE+A+AA AGIPIRIGVNAGSLDKR + KYGKATPEALVESALWE SLFEE Sbjct 123 IKKFDDKVGEIARAAKGAGIPIRIGVNAGSLDKRLLAKYGKATPEALVESALWECSLFEE 182 Query 181 HGFGDIKISVKHNDPVVMVAAYELLAARCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSR 240 H F DIKISVKHN+PVVMV AYELLAA+CDYPLHLGVTEAGPAFQGTIKSAVAFGALLS+ Sbjct 183 HDFRDIKISVKHNNPVVMVRAYELLAAQCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSQ 242 Query 241 GIGDTIRVSLSAPPVEEVKVGNQVLESLNLRPRSLEIVSCPSCGRAQVDVYTLANEVTAG 300 GIGDTIRVSLSAPP EEVKVG Q+LESLNLR R LEIVSCPSCGRAQVDVY LA+EVTAG Sbjct 243 GIGDTIRVSLSAPPAEEVKVGTQILESLNLRQRGLEIVSCPSCGRAQVDVYKLADEVTAG 302 Query 301 LDGLDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPEAQIVETLIE 360 LDGL+VPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFV+GEV+KTVPE+QIVETLIE Sbjct 303 LDGLEVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVKGEVVKTVPESQIVETLIE 362 Query 361 EAMRLAAEMGEQDPGATPSGSPIVTVS 387 EAMRLA M D G +P GSP+VTV+ Sbjct 363 EAMRLADGMTAAD-GTSP-GSPVVTVA 387 >gi|227833374|ref|YP_002835081.1| 4-hydroxy-3-methylbut-2-enyl diphosphate synthase [Corynebacterium aurimucosum ATCC 700975] gi|262184360|ref|ZP_06043781.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Corynebacterium aurimucosum ATCC 700975] gi|227454390|gb|ACP33143.1| 4-hydroxy-3-methylbut-2-enyl diphosphate synthase [Corynebacterium aurimucosum ATCC 700975] Length=387 Score = 648 bits (1671), Expect = 0.0, Method: Compositional matrix adjust. Identities = 314/368 (86%), Positives = 340/368 (93%), Gaps = 0/368 (0%) Query 3 VGLGMPQPPAPTLAPRRATRQLMVGNVGVGSDHPVSVQSMCTTKTHDVNSTLQQIAELTA 62 +GLG+P P PTLAPRR TRQLMVG VGVGSDHP+SVQSM TTKTHD+N+TLQQIA+LTA Sbjct 5 IGLGIPDGPPPTLAPRRKTRQLMVGQVGVGSDHPISVQSMTTTKTHDINATLQQIAQLTA 64 Query 63 AGCDIVRVACPRQEDADALAEIARHSQIPVVADIHFQPRYIFAAIDAGCAAVRVNPGNIK 122 +GCDIVRVACP+ DA+AL IA+ S IPV+ADIHFQP+YIFAAIDAGCAAVRVNPGNIK Sbjct 65 SGCDIVRVACPKTVDAEALPAIAQKSPIPVIADIHFQPKYIFAAIDAGCAAVRVNPGNIK 124 Query 123 EFDGRVGEVAKAAGAAGIPIRIGVNAGSLDKRFMEKYGKATPEALVESALWEASLFEEHG 182 EFDGRV EVAKAAG AGIPIRIGVNAGSLDKR MEKYGKATPEALVESALWEA LFEEHG Sbjct 125 EFDGRVKEVAKAAGDAGIPIRIGVNAGSLDKRIMEKYGKATPEALVESALWEAGLFEEHG 184 Query 183 FGDIKISVKHNDPVVMVAAYELLAARCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSRGI 242 +GDI ISVKHNDPVVMV AY LAA+CDYPLHLGVTEAGPAFQGTIKS+VAFGALL+ GI Sbjct 185 YGDIVISVKHNDPVVMVEAYRQLAAQCDYPLHLGVTEAGPAFQGTIKSSVAFGALLAEGI 244 Query 243 GDTIRVSLSAPPVEEVKVGNQVLESLNLRPRSLEIVSCPSCGRAQVDVYTLANEVTAGLD 302 GDTIRVSLSA PVEE+KVG+Q+L+SLNLRPR LEIVSCPSCGRAQVDVY LANEVT GLD Sbjct 245 GDTIRVSLSADPVEEIKVGDQILQSLNLRPRKLEIVSCPSCGRAQVDVYKLANEVTEGLD 304 Query 303 GLDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPEAQIVETLIEEA 362 G++ PLRVAVMGCVVNGPGEAR+ADLGVASGNGKGQIFV+GEVIKTVPE++IVETLIEEA Sbjct 305 GMEFPLRVAVMGCVVNGPGEARDADLGVASGNGKGQIFVKGEVIKTVPESKIVETLIEEA 364 Query 363 MRLAAEMG 370 MRLA E G Sbjct 365 MRLAEEQG 372 >gi|183980306|ref|YP_001848597.1| GcpE protein [Mycobacterium marinum M] gi|183173632|gb|ACC38742.1| GcpE protein [Mycobacterium marinum M] Length=387 Score = 644 bits (1661), Expect = 0.0, Method: Compositional matrix adjust. Identities = 324/385 (85%), Positives = 354/385 (92%), Gaps = 0/385 (0%) Query 1 VTVGLGMPQPPAPTLAPRRATRQLMVGNVGVGSDHPVSVQSMCTTKTHDVNSTLQQIAEL 60 +T+GLG+P PPAP LAPRR TRQLMVGNVG+GSD+PV+VQSM TTKTHDVN+TLQQIAEL Sbjct 1 MTIGLGIPAPPAPRLAPRRVTRQLMVGNVGIGSDYPVAVQSMTTTKTHDVNATLQQIAEL 60 Query 61 TAAGCDIVRVACPRQEDADALAEIARHSQIPVVADIHFQPRYIFAAIDAGCAAVRVNPGN 120 TAAGC+IVRVACPRQEDADAL +I +HS IPV+ADIHFQP+YIFAAIDAGCAAVRVNPGN Sbjct 61 TAAGCNIVRVACPRQEDADALPQIVKHSHIPVIADIHFQPKYIFAAIDAGCAAVRVNPGN 120 Query 121 IKEFDGRVGEVAKAAGAAGIPIRIGVNAGSLDKRFMEKYGKATPEALVESALWEASLFEE 180 IKEFD RV EVAKAA GIPIRIGVNAGSL KR +++YGKATPEALVESALWEASLFEE Sbjct 121 IKEFDSRVKEVAKAAADTGIPIRIGVNAGSLGKRIIQRYGKATPEALVESALWEASLFEE 180 Query 181 HGFGDIKISVKHNDPVVMVAAYELLAARCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSR 240 HGFGDIKISVKH+DPVVMVAAY+LLA +CDYPLHLGVTEAGPAFQGTIKSAVAFGALLS Sbjct 181 HGFGDIKISVKHHDPVVMVAAYQLLATQCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSS 240 Query 241 GIGDTIRVSLSAPPVEEVKVGNQVLESLNLRPRSLEIVSCPSCGRAQVDVYTLANEVTAG 300 GIGDTIRVSLSAPP+EEVKVG Q+LESLNLRPRSLEIVSCPSCGRAQVDVY LANEV+AG Sbjct 241 GIGDTIRVSLSAPPIEEVKVGTQILESLNLRPRSLEIVSCPSCGRAQVDVYRLANEVSAG 300 Query 301 LDGLDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPEAQIVETLIE 360 LDGL PLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFV+GEVIKTVPE+QIVETLIE Sbjct 301 LDGLGAPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVKGEVIKTVPESQIVETLIE 360 Query 361 EAMRLAAEMGEQDPGATPSGSPIVT 385 +A+R+A E + G+P+V+ Sbjct 361 QALRIAEERASETECTDLVGTPVVS 385 >gi|325001857|ref|ZP_08122969.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Pseudonocardia sp. P1] Length=385 Score = 640 bits (1650), Expect = 0.0, Method: Compositional matrix adjust. Identities = 318/386 (83%), Positives = 345/386 (90%), Gaps = 2/386 (0%) Query 1 VTVGLGMPQPPAPTLAPRRATRQLMVGNVGVGSDHPVSVQSMCTTKTHDVNSTLQQIAEL 60 ++V LGMP PAPTLAPRR TRQL VG VGVGSDHP+SVQSM TT T DVN+TLQQIAEL Sbjct 1 MSVSLGMPSAPAPTLAPRRKTRQLQVGPVGVGSDHPISVQSMTTTLTSDVNATLQQIAEL 60 Query 61 TAAGCDIVRVACPRQEDADALAEIARHSQIPVVADIHFQPRYIFAAIDAGCAAVRVNPGN 120 TA+GCDIVRVACP +DA+AL IA+ SQIPV+ADIHFQP+Y+FAAI+AGCAAVRVNPGN Sbjct 61 TASGCDIVRVACPSADDAEALPAIAQKSQIPVIADIHFQPKYVFAAIEAGCAAVRVNPGN 120 Query 121 IKEFDGRVGEVAKAAGAAGIPIRIGVNAGSLDKRFMEKYGKATPEALVESALWEASLFEE 180 I++FD +V E+A AA G PIRIGVNAGSLDKR MEK+GKATPEAL ESALWEASLF E Sbjct 121 IRKFDDQVKEIAHAARDHGTPIRIGVNAGSLDKRLMEKHGKATPEALAESALWEASLFAE 180 Query 181 HGFGDIKISVKHNDPVVMVAAYELLAARCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSR 240 H F DIKISVKHNDPVVMV AYELLA +CDYPLHLGVTEAGPAFQGTIKSAVAFGALL + Sbjct 181 HDFHDIKISVKHNDPVVMVRAYELLAEQCDYPLHLGVTEAGPAFQGTIKSAVAFGALLRQ 240 Query 241 GIGDTIRVSLSAPPVEEVKVGNQVLESLNLRPRSLEIVSCPSCGRAQVDVYTLANEVTAG 300 GIGDTIRVSLSAPPVEE+KVG Q+LESLNLRPR LEIVSCPSCGRAQVDVYTLA+EVTAG Sbjct 241 GIGDTIRVSLSAPPVEEIKVGQQILESLNLRPRKLEIVSCPSCGRAQVDVYTLADEVTAG 300 Query 301 LDGLDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPEAQIVETLIE 360 L G++VPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFV+GEVIKTVPE +IVETLIE Sbjct 301 LTGMEVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVKGEVIKTVPEHKIVETLIE 360 Query 361 EAMRLAAEMGEQDPGATPSGSPIVTV 386 EAMR+A EMGE GAT G P VTV Sbjct 361 EAMRIAEEMGEPVDGAT--GEPQVTV 384 >gi|337291018|ref|YP_004630039.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Corynebacterium ulcerans BR-AD22] gi|334697131|gb|AEG81928.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Corynebacterium ulcerans 809] gi|334699324|gb|AEG84120.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Corynebacterium ulcerans BR-AD22] Length=391 Score = 639 bits (1648), Expect = 0.0, Method: Compositional matrix adjust. Identities = 318/377 (85%), Positives = 342/377 (91%), Gaps = 1/377 (0%) Query 3 VGLGMPQPPAPTLAPRRATRQLMVGNVGVGSDHPVSVQSMCTTKTHDVNSTLQQIAELTA 62 +GLG+P P P LAPRR TRQ+MVGNVGVGSD+PVSVQSM TTKTHDVN+TLQQIA+LTA Sbjct 9 IGLGLPDAPPPVLAPRRKTRQIMVGNVGVGSDYPVSVQSMTTTKTHDVNATLQQIAQLTA 68 Query 63 AGCDIVRVACPRQEDADALAEIARHSQIPVVADIHFQPRYIFAAIDAGCAAVRVNPGNIK 122 +GCDI+RVACP+ DA+AL IA+ S IPV+ADIHFQP+YIFAAIDAGCAAVRVNPGNIK Sbjct 69 SGCDIIRVACPKTVDAEALPIIAKKSPIPVIADIHFQPKYIFAAIDAGCAAVRVNPGNIK 128 Query 123 EFDGRVGEVAKAAGAAGIPIRIGVNAGSLDKRFMEKYGKATPEALVESALWEASLFEEHG 182 EFDGRV EVAKAAG AGIPIRIGVNAGSLDKR +EKYGKATPEALVESALWEA LFE+ G Sbjct 129 EFDGRVKEVAKAAGDAGIPIRIGVNAGSLDKRLLEKYGKATPEALVESALWEAGLFEDCG 188 Query 183 FGDIKISVKHNDPVVMVAAYELLAARCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSRGI 242 FGDI ISVKHNDPVVMV AY LAA+ DYPLHLGVTEAGPAFQGTIKSAVAFGALLS GI Sbjct 189 FGDIAISVKHNDPVVMVEAYRQLAAQSDYPLHLGVTEAGPAFQGTIKSAVAFGALLSEGI 248 Query 243 GDTIRVSLSAPPVEEVKVGNQVLESLNLRPRSLEIVSCPSCGRAQVDVYTLANEVTAGLD 302 GDTIRVSLSA PVEE+KVG+Q+L+SLNLR R LEIVSCPSCGRAQVDVYTLA EVTA LD Sbjct 249 GDTIRVSLSADPVEEIKVGDQILQSLNLRERGLEIVSCPSCGRAQVDVYTLAEEVTAALD 308 Query 303 GLDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPEAQIVETLIEEA 362 G+D+PLRVAVMGCVVNGPGEAR+ADLGVASGNGKGQIFVRGEVIKTVPE+QIVETLIEEA Sbjct 309 GMDIPLRVAVMGCVVNGPGEARDADLGVASGNGKGQIFVRGEVIKTVPESQIVETLIEEA 368 Query 363 MRLA-AEMGEQDPGATP 378 MRLA AE E GA P Sbjct 369 MRLAEAEGLEIKEGAGP 385 >gi|300858720|ref|YP_003783703.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Corynebacterium pseudotuberculosis FRC41] gi|300686174|gb|ADK29096.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Corynebacterium pseudotuberculosis FRC41] gi|302206429|gb|ADL10771.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Corynebacterium pseudotuberculosis C231] gi|302330985|gb|ADL21179.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Corynebacterium pseudotuberculosis 1002] gi|308276671|gb|ADO26570.1| Putative 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Corynebacterium pseudotuberculosis I19] gi|341825113|gb|AEK92634.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Corynebacterium pseudotuberculosis PAT10] Length=391 Score = 639 bits (1647), Expect = 0.0, Method: Compositional matrix adjust. Identities = 316/377 (84%), Positives = 341/377 (91%), Gaps = 1/377 (0%) Query 3 VGLGMPQPPAPTLAPRRATRQLMVGNVGVGSDHPVSVQSMCTTKTHDVNSTLQQIAELTA 62 +GLG+P P P LAPRR TRQ+MVGNVGVGSD+PVSVQSM TTKTHDVN+TLQQIA+LTA Sbjct 9 IGLGLPDAPPPVLAPRRKTRQIMVGNVGVGSDYPVSVQSMTTTKTHDVNATLQQIAQLTA 68 Query 63 AGCDIVRVACPRQEDADALAEIARHSQIPVVADIHFQPRYIFAAIDAGCAAVRVNPGNIK 122 +GCDI+RVACP+ DA+AL IA+ S IPV+ADIHFQP+YIFAAIDAGCAAVRVNPGNIK Sbjct 69 SGCDIIRVACPKTVDAEALPIIAKKSPIPVIADIHFQPKYIFAAIDAGCAAVRVNPGNIK 128 Query 123 EFDGRVGEVAKAAGAAGIPIRIGVNAGSLDKRFMEKYGKATPEALVESALWEASLFEEHG 182 EFDGRV EVAKAAG AGIPIRIGVNAGSLDKR +EKYGKATPEALVESALWEA LFE+ G Sbjct 129 EFDGRVKEVAKAAGDAGIPIRIGVNAGSLDKRLLEKYGKATPEALVESALWEAGLFEDCG 188 Query 183 FGDIKISVKHNDPVVMVAAYELLAARCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSRGI 242 FGDI ISVKHNDPVVMV AY LAA+ DYPLHLGVTEAGPAFQGTIKS+VAFGALLS GI Sbjct 189 FGDIAISVKHNDPVVMVEAYRQLAAQSDYPLHLGVTEAGPAFQGTIKSSVAFGALLSEGI 248 Query 243 GDTIRVSLSAPPVEEVKVGNQVLESLNLRPRSLEIVSCPSCGRAQVDVYTLANEVTAGLD 302 GDTIRVSLSA PVEE+KVG+Q+L+SLNLR R LEIVSCPSCGRAQVDVYTLA EVTA LD Sbjct 249 GDTIRVSLSADPVEEIKVGDQILQSLNLRERGLEIVSCPSCGRAQVDVYTLAEEVTAALD 308 Query 303 GLDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPEAQIVETLIEEA 362 G+D+PLRVAVMGCVVNGPGEAR+ADLGVASGNGKGQIFVRGEVIKTVPE+QIVETLIEEA Sbjct 309 GMDIPLRVAVMGCVVNGPGEARDADLGVASGNGKGQIFVRGEVIKTVPESQIVETLIEEA 368 Query 363 MRLAAEMG-EQDPGATP 378 MRLA G E GA P Sbjct 369 MRLAESEGLEIKEGAGP 385 >gi|68536242|ref|YP_250947.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Corynebacterium jeikeium K411] gi|123734573|sp|Q4JV28.1|ISPG_CORJK RecName: Full=4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; AltName: Full=1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase gi|68263841|emb|CAI37329.1| 4-hydroxy-3-methylbut-2-enyl diphosphate synthase [Corynebacterium jeikeium K411] Length=386 Score = 638 bits (1646), Expect = 0.0, Method: Compositional matrix adjust. Identities = 311/368 (85%), Positives = 337/368 (92%), Gaps = 0/368 (0%) Query 3 VGLGMPQPPAPTLAPRRATRQLMVGNVGVGSDHPVSVQSMCTTKTHDVNSTLQQIAELTA 62 + LG+P P P LAPRR TRQLMVG VGVGSDHP+SVQSM TTKTHDVN+TLQQIA+LTA Sbjct 4 ISLGIPDGPPPVLAPRRKTRQLMVGGVGVGSDHPISVQSMTTTKTHDVNATLQQIAQLTA 63 Query 63 AGCDIVRVACPRQEDADALAEIARHSQIPVVADIHFQPRYIFAAIDAGCAAVRVNPGNIK 122 +GCDIVRVACP+ DA+AL IA S IPV+ADIHFQP+YIF+AIDAGCAAVRVNPGNIK Sbjct 64 SGCDIVRVACPKTVDAEALPAIAAKSPIPVIADIHFQPKYIFSAIDAGCAAVRVNPGNIK 123 Query 123 EFDGRVGEVAKAAGAAGIPIRIGVNAGSLDKRFMEKYGKATPEALVESALWEASLFEEHG 182 EFDGRV EVAKAAG AGIPIRIGVNAGSLDKR MEKYGKATPEALVESALWEASLFEEHG Sbjct 124 EFDGRVKEVAKAAGDAGIPIRIGVNAGSLDKRIMEKYGKATPEALVESALWEASLFEEHG 183 Query 183 FGDIKISVKHNDPVVMVAAYELLAARCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSRGI 242 +GDI ISVKHNDPVVMV AY LAA+ DYPLHLGVTEAGPAFQGTIKS+VAFGALL+ GI Sbjct 184 YGDIAISVKHNDPVVMVEAYRQLAAQSDYPLHLGVTEAGPAFQGTIKSSVAFGALLAEGI 243 Query 243 GDTIRVSLSAPPVEEVKVGNQVLESLNLRPRSLEIVSCPSCGRAQVDVYTLANEVTAGLD 302 GDTIRVSLSA PVEE+KVG+Q+L+SLNLRPR LEIVSCPSCGRAQVDVY LA+EVTAGL+ Sbjct 244 GDTIRVSLSADPVEEIKVGDQILQSLNLRPRKLEIVSCPSCGRAQVDVYKLADEVTAGLE 303 Query 303 GLDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPEAQIVETLIEEA 362 G++ PLRVAVMGCVVNGPGEAR+ADLGVASGNGKGQIFV+GEVIKTVPE QIVETLIEEA Sbjct 304 GMEFPLRVAVMGCVVNGPGEARDADLGVASGNGKGQIFVKGEVIKTVPEDQIVETLIEEA 363 Query 363 MRLAAEMG 370 MR+A E G Sbjct 364 MRIAEEEG 371 >gi|260578942|ref|ZP_05846845.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Corynebacterium jeikeium ATCC 43734] gi|258602916|gb|EEW16190.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Corynebacterium jeikeium ATCC 43734] Length=386 Score = 637 bits (1644), Expect = 0.0, Method: Compositional matrix adjust. Identities = 311/368 (85%), Positives = 337/368 (92%), Gaps = 0/368 (0%) Query 3 VGLGMPQPPAPTLAPRRATRQLMVGNVGVGSDHPVSVQSMCTTKTHDVNSTLQQIAELTA 62 + LG+P P P LAPRR TRQLMVG VGVGSDHP+SVQSM TTKTHDVN+TLQQIA+LTA Sbjct 4 ISLGIPDGPPPVLAPRRKTRQLMVGGVGVGSDHPISVQSMTTTKTHDVNATLQQIAQLTA 63 Query 63 AGCDIVRVACPRQEDADALAEIARHSQIPVVADIHFQPRYIFAAIDAGCAAVRVNPGNIK 122 +GCDIVRVACP+ DA+AL IA S IPV+ADIHFQP+YIF+AIDAGCAAVRVNPGNIK Sbjct 64 SGCDIVRVACPKTVDAEALPAIAAKSPIPVIADIHFQPKYIFSAIDAGCAAVRVNPGNIK 123 Query 123 EFDGRVGEVAKAAGAAGIPIRIGVNAGSLDKRFMEKYGKATPEALVESALWEASLFEEHG 182 EFDGRV EVAKAAG AGIPIRIGVNAGSLDKR MEKYGKATPEALVESA+WEASLFEEHG Sbjct 124 EFDGRVKEVAKAAGDAGIPIRIGVNAGSLDKRIMEKYGKATPEALVESAVWEASLFEEHG 183 Query 183 FGDIKISVKHNDPVVMVAAYELLAARCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSRGI 242 FGDI ISVKHNDPVVMV AY LAA+ DYPLHLGVTEAGPAFQGTIKS+VAFGALL+ GI Sbjct 184 FGDIAISVKHNDPVVMVEAYRQLAAQTDYPLHLGVTEAGPAFQGTIKSSVAFGALLAEGI 243 Query 243 GDTIRVSLSAPPVEEVKVGNQVLESLNLRPRSLEIVSCPSCGRAQVDVYTLANEVTAGLD 302 GDTIRVSLSA PVEE+KVG+Q+L+SLNLRPR LEIVSCPSCGRAQVDVY LA+EVTAGL+ Sbjct 244 GDTIRVSLSADPVEEIKVGDQILQSLNLRPRKLEIVSCPSCGRAQVDVYKLADEVTAGLE 303 Query 303 GLDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPEAQIVETLIEEA 362 G++ PLRVAVMGCVVNGPGEAR+ADLGVASGNGKGQIFV+GEVIKTVPE QIVETLIEEA Sbjct 304 GMEFPLRVAVMGCVVNGPGEARDADLGVASGNGKGQIFVKGEVIKTVPEDQIVETLIEEA 363 Query 363 MRLAAEMG 370 MR+A E G Sbjct 364 MRIAEEEG 371 >gi|317506018|ref|ZP_07963848.1| GcpE protein [Segniliparus rugosus ATCC BAA-974] gi|316255676|gb|EFV14916.1| GcpE protein [Segniliparus rugosus ATCC BAA-974] Length=381 Score = 636 bits (1641), Expect = 1e-180, Method: Compositional matrix adjust. Identities = 319/386 (83%), Positives = 342/386 (89%), Gaps = 7/386 (1%) Query 2 TVGLGMPQPPAPTLAPRRATRQLMVGNVGVGSDHPVSVQSMCTTKTHDVNSTLQQIAELT 61 +V LGMP PPA LAPRR TRQL +G VGVGSD PVSVQSM TTKTHDVN+TLQQIA+LT Sbjct 3 SVELGMPAPPAQVLAPRRRTRQLRLGPVGVGSDSPVSVQSMTTTKTHDVNATLQQIAQLT 62 Query 62 AAGCDIVRVACPRQEDADALAEIARHSQIPVVADIHFQPRYIFAAIDAGCAAVRVNPGNI 121 AAGCD+VRVACPRQEDADALA IA+ SQIPV+ADIHFQPRYIFAAI+AGCA VRVNPGNI Sbjct 63 AAGCDVVRVACPRQEDADALAAIAKKSQIPVIADIHFQPRYIFAAIEAGCAGVRVNPGNI 122 Query 122 KEFDGRVGEVAKAAGAAGIPIRIGVNAGSLDKRFMEKYGKATPEALVESALWEASLFEEH 181 KEFDGRV EVA AA A PIRIGVNAGSLD R + KYGKATPEALVESALWEA LF EH Sbjct 123 KEFDGRVKEVALAASDAKTPIRIGVNAGSLDPRILAKYGKATPEALVESALWEAGLFAEH 182 Query 182 GFGDIKISVKHNDPVVMVAAYELLAARCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSRG 241 GF D+KISVKHNDPV MV AYELLA +CDYPLHLGVTEAGPAFQGTIKSAVAFGALLS+G Sbjct 183 GFFDLKISVKHNDPVTMVRAYELLAEQCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSKG 242 Query 242 IGDTIRVSLSAPPVEEVKVGNQVLESLNLRPRSLEIVSCPSCGRAQVDVYTLANEVTAGL 301 IGDTIRVSLSAPPVEEVKVG Q+L SL L+ R+LEIVSCPSCGRAQVDVYTLA +VTAGL Sbjct 243 IGDTIRVSLSAPPVEEVKVGQQILMSLGLKERTLEIVSCPSCGRAQVDVYTLAEQVTAGL 302 Query 302 DGLDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPEAQIVETLIEE 361 +G++VPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFV+GEVIKTVPE IVETLIEE Sbjct 303 EGIEVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVKGEVIKTVPEHLIVETLIEE 362 Query 362 AMRLAAEMGEQDPGATPSGSPIVTVS 387 A+R+A E GE+ GSP VTVS Sbjct 363 ALRIAEETGER-------GSPQVTVS 381 >gi|336325808|ref|YP_004605774.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Corynebacterium resistens DSM 45100] gi|336101790|gb|AEI09610.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Corynebacterium resistens DSM 45100] Length=386 Score = 635 bits (1638), Expect = 3e-180, Method: Compositional matrix adjust. Identities = 310/368 (85%), Positives = 337/368 (92%), Gaps = 0/368 (0%) Query 3 VGLGMPQPPAPTLAPRRATRQLMVGNVGVGSDHPVSVQSMCTTKTHDVNSTLQQIAELTA 62 + LG+P P PTLAPRR TRQLMVGNVGVGSD+P+SVQSM TTKTHDVN+TLQQIA+LTA Sbjct 4 ISLGIPDGPPPTLAPRRKTRQLMVGNVGVGSDYPISVQSMTTTKTHDVNATLQQIAQLTA 63 Query 63 AGCDIVRVACPRQEDADALAEIARHSQIPVVADIHFQPRYIFAAIDAGCAAVRVNPGNIK 122 +GCDIVRVACP+ DA+AL IA+ S IPV+ADIHFQP+YIFAAIDAGCAAVRVNPGNIK Sbjct 64 SGCDIVRVACPKTVDAEALPAIAKKSPIPVIADIHFQPKYIFAAIDAGCAAVRVNPGNIK 123 Query 123 EFDGRVGEVAKAAGAAGIPIRIGVNAGSLDKRFMEKYGKATPEALVESALWEASLFEEHG 182 EFDGRV EVAKAAG AGIPIRIGVNAGSLDKR MEKYGKATPEALVESALWEA LFE+ G Sbjct 124 EFDGRVKEVAKAAGDAGIPIRIGVNAGSLDKRIMEKYGKATPEALVESALWEAGLFEDCG 183 Query 183 FGDIKISVKHNDPVVMVAAYELLAARCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSRGI 242 FGDI ISVKHNDPVVMV AY LA + DYPLHLGVTEAGPAFQGTIKS+VAFGALLS+GI Sbjct 184 FGDIAISVKHNDPVVMVEAYRQLAEKSDYPLHLGVTEAGPAFQGTIKSSVAFGALLSQGI 243 Query 243 GDTIRVSLSAPPVEEVKVGNQVLESLNLRPRSLEIVSCPSCGRAQVDVYTLANEVTAGLD 302 GDTIRVSLSA PVEE+KVG+Q+L+S+NLRPR LEIVSCPSCGRAQVDVY LA EVTAGL+ Sbjct 244 GDTIRVSLSADPVEEIKVGDQILQSMNLRPRKLEIVSCPSCGRAQVDVYKLAEEVTAGLE 303 Query 303 GLDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPEAQIVETLIEEA 362 G++ PLRVAVMGCVVNGPGEAR+ADLGVASGNGKGQIFV+GEVIKTVPE QIVETLIEEA Sbjct 304 GMEFPLRVAVMGCVVNGPGEARDADLGVASGNGKGQIFVKGEVIKTVPEDQIVETLIEEA 363 Query 363 MRLAAEMG 370 MR+A E G Sbjct 364 MRIADEEG 371 >gi|38234077|ref|NP_939844.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Corynebacterium diphtheriae NCTC 13129] gi|50400886|sp|Q6NGL3.1|ISPG_CORDI RecName: Full=4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; AltName: Full=1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase gi|38200339|emb|CAE50025.1| Conserved hypothetical protein [Corynebacterium diphtheriae] Length=391 Score = 635 bits (1638), Expect = 4e-180, Method: Compositional matrix adjust. Identities = 314/377 (84%), Positives = 343/377 (91%), Gaps = 1/377 (0%) Query 3 VGLGMPQPPAPTLAPRRATRQLMVGNVGVGSDHPVSVQSMCTTKTHDVNSTLQQIAELTA 62 +GLG+P P P LAPRR TRQLMVGNVGVGSD+PVSVQSM TTKTHDVN+TLQQIA+LTA Sbjct 9 IGLGLPDAPLPVLAPRRKTRQLMVGNVGVGSDYPVSVQSMTTTKTHDVNATLQQIAQLTA 68 Query 63 AGCDIVRVACPRQEDADALAEIARHSQIPVVADIHFQPRYIFAAIDAGCAAVRVNPGNIK 122 +GCDIVRVACP+ DA+AL IA+ S IPV+ADIHFQP+YIF+AIDAGCAAVRVNPGNIK Sbjct 69 SGCDIVRVACPKTVDAEALPAIAKKSPIPVIADIHFQPKYIFSAIDAGCAAVRVNPGNIK 128 Query 123 EFDGRVGEVAKAAGAAGIPIRIGVNAGSLDKRFMEKYGKATPEALVESALWEASLFEEHG 182 EFDGRV EVAKAAG AGIPIRIGVNAGSLDKR MEKYGKATPEALVESALWEA LFE+ G Sbjct 129 EFDGRVKEVAKAAGDAGIPIRIGVNAGSLDKRIMEKYGKATPEALVESALWEAGLFEDCG 188 Query 183 FGDIKISVKHNDPVVMVAAYELLAARCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSRGI 242 FGDI ISVKHNDPV+MV AY LAA+ DYPLHLGVTEAGPAFQGTIKS+VAFG+LLS+GI Sbjct 189 FGDIAISVKHNDPVIMVEAYRQLAAQSDYPLHLGVTEAGPAFQGTIKSSVAFGSLLSQGI 248 Query 243 GDTIRVSLSAPPVEEVKVGNQVLESLNLRPRSLEIVSCPSCGRAQVDVYTLANEVTAGLD 302 GDTIRVSLSA PVEE+KVG+Q+L+SLNLR R LEIVSCPSCGRAQVDVY+LA EVTA LD Sbjct 249 GDTIRVSLSADPVEEIKVGDQILQSLNLRKRGLEIVSCPSCGRAQVDVYSLAEEVTAALD 308 Query 303 GLDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPEAQIVETLIEEA 362 G+ +PLRVAVMGCVVNGPGEAR+ADLGVASGNGKGQIFVRGEVIKTVPE+QIVETLIEEA Sbjct 309 GMSIPLRVAVMGCVVNGPGEARDADLGVASGNGKGQIFVRGEVIKTVPESQIVETLIEEA 368 Query 363 MRLA-AEMGEQDPGATP 378 +RLA AE E + GA P Sbjct 369 VRLAEAEGLEIEEGAGP 385 >gi|172040513|ref|YP_001800227.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Corynebacterium urealyticum DSM 7109] gi|254806873|sp|B1VGA4.1|ISPG_CORU7 RecName: Full=4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; AltName: Full=1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase gi|171851817|emb|CAQ04793.1| 4-hydroxy-3-methylbut-2-enyl diphosphate synthase [Corynebacterium urealyticum DSM 7109] Length=386 Score = 632 bits (1631), Expect = 3e-179, Method: Compositional matrix adjust. Identities = 307/368 (84%), Positives = 337/368 (92%), Gaps = 0/368 (0%) Query 3 VGLGMPQPPAPTLAPRRATRQLMVGNVGVGSDHPVSVQSMCTTKTHDVNSTLQQIAELTA 62 + LG+P P PTLAPRR TRQLMVG+VGVGS+HP+SVQSM TTKTHD+N+TLQQIA+LTA Sbjct 4 ISLGIPDGPPPTLAPRRKTRQLMVGDVGVGSEHPISVQSMTTTKTHDINATLQQIAQLTA 63 Query 63 AGCDIVRVACPRQEDADALAEIARHSQIPVVADIHFQPRYIFAAIDAGCAAVRVNPGNIK 122 +GCDIVRVACP+ DA+AL IA+ S IPV+ADIHFQPRYIF AI+AGCAAVRVNPGNIK Sbjct 64 SGCDIVRVACPKPRDAEALPIIAKKSPIPVIADIHFQPRYIFQAIEAGCAAVRVNPGNIK 123 Query 123 EFDGRVGEVAKAAGAAGIPIRIGVNAGSLDKRFMEKYGKATPEALVESALWEASLFEEHG 182 EFDGRV EVAKAAG AGIPIRIGVN GSLDKR +EKYGKATPEALVESA+WEA LFEEHG Sbjct 124 EFDGRVKEVAKAAGDAGIPIRIGVNGGSLDKRLLEKYGKATPEALVESAIWEAGLFEEHG 183 Query 183 FGDIKISVKHNDPVVMVAAYELLAARCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSRGI 242 FGDI ISVKH+DPVVMV AY LAA+ DYPLHLGVTEAGPAFQGTIKS+VAFGALLS+GI Sbjct 184 FGDIAISVKHSDPVVMVEAYRQLAAKTDYPLHLGVTEAGPAFQGTIKSSVAFGALLSQGI 243 Query 243 GDTIRVSLSAPPVEEVKVGNQVLESLNLRPRSLEIVSCPSCGRAQVDVYTLANEVTAGLD 302 GDTIRVSLSA PVEE+KVG+Q+L+SLNLRPR LEIVSCPSCGRAQVDVYTLA EVTAGL+ Sbjct 244 GDTIRVSLSADPVEEIKVGDQILQSLNLRPRKLEIVSCPSCGRAQVDVYTLAEEVTAGLE 303 Query 303 GLDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPEAQIVETLIEEA 362 G++ PLRVAVMGCVVNGPGEAR+ADLGVASGNGKGQIFV+GEVIKTVPE QIVETLIEEA Sbjct 304 GMEFPLRVAVMGCVVNGPGEARDADLGVASGNGKGQIFVKGEVIKTVPEDQIVETLIEEA 363 Query 363 MRLAAEMG 370 R+A E G Sbjct 364 HRIAEEQG 371 >gi|296394682|ref|YP_003659566.1| 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase [Segniliparus rotundus DSM 44985] gi|296181829|gb|ADG98735.1| 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase [Segniliparus rotundus DSM 44985] Length=382 Score = 632 bits (1629), Expect = 4e-179, Method: Compositional matrix adjust. Identities = 320/386 (83%), Positives = 343/386 (89%), Gaps = 6/386 (1%) Query 2 TVGLGMPQPPAPTLAPRRATRQLMVGNVGVGSDHPVSVQSMCTTKTHDVNSTLQQIAELT 61 +V LGMP PPA LAPRR TRQL +G VGVGSDHPVSVQSM TTKTHDVN+TLQQIAELT Sbjct 3 SVELGMPAPPAQVLAPRRQTRQLKLGPVGVGSDHPVSVQSMTTTKTHDVNATLQQIAELT 62 Query 62 AAGCDIVRVACPRQEDADALAEIARHSQIPVVADIHFQPRYIFAAIDAGCAAVRVNPGNI 121 AAGCD+VRVACPRQEDADALA IA+ SQIPV+ADIHFQPRYIFAAIDAGCA VRVNPGNI Sbjct 63 AAGCDLVRVACPRQEDADALAAIAKKSQIPVIADIHFQPRYIFAAIDAGCAGVRVNPGNI 122 Query 122 KEFDGRVGEVAKAAGAAGIPIRIGVNAGSLDKRFMEKYGKATPEALVESALWEASLFEEH 181 KEFDGRV EVA+AA AA PIRIGVNAGSLD R + KYGKATPEALVESALWEA LF EH Sbjct 123 KEFDGRVKEVAQAAAAANTPIRIGVNAGSLDPRLLAKYGKATPEALVESALWEAGLFAEH 182 Query 182 GFGDIKISVKHNDPVVMVAAYELLAARCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSRG 241 GF D+KISVKHNDPV MV AYELLA +CDYPLHLGVTEAGPAFQGTIKSAVAFG LL +G Sbjct 183 GFFDLKISVKHNDPVTMVRAYELLAEQCDYPLHLGVTEAGPAFQGTIKSAVAFGVLLGKG 242 Query 242 IGDTIRVSLSAPPVEEVKVGNQVLESLNLRPRSLEIVSCPSCGRAQVDVYTLANEVTAGL 301 IGDTIRVSLSAPPVEEVKVG Q+L+SL L+ R+LEIVSCPSCGRAQVDVYTLA +VTAGL Sbjct 243 IGDTIRVSLSAPPVEEVKVGQQILQSLGLKERTLEIVSCPSCGRAQVDVYTLAEQVTAGL 302 Query 302 DGLDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPEAQIVETLIEE 361 +G++VPLRVAVMGCVVNGPGEAREADLGVASGNG+GQIFV+GEVIKTVPE IVETLIEE Sbjct 303 EGIEVPLRVAVMGCVVNGPGEAREADLGVASGNGRGQIFVKGEVIKTVPEHLIVETLIEE 362 Query 362 AMRLAAEMGEQDPGATPSGSPIVTVS 387 A+R+A E G Q SG P VTVS Sbjct 363 ALRIAEESGLQ------SGVPEVTVS 382 >gi|317125365|ref|YP_004099477.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Intrasporangium calvum DSM 43043] gi|315589453|gb|ADU48750.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Intrasporangium calvum DSM 43043] Length=386 Score = 632 bits (1629), Expect = 4e-179, Method: Compositional matrix adjust. Identities = 313/386 (82%), Positives = 343/386 (89%), Gaps = 1/386 (0%) Query 1 VTVGLGMPQPPAPTLAPRRATRQLMVGNVGVGSDHPVSVQSMCTTKTHDVNSTLQQIAEL 60 +TV LGMP PAP LAPRR TRQ+ VG VGVGSD PVSVQSM TT T D+N+TLQQIAEL Sbjct 1 MTVSLGMPSAPAPVLAPRRQTRQIRVGKVGVGSDFPVSVQSMTTTPTTDINATLQQIAEL 60 Query 61 TAAGCDIVRVACPRQEDADALAEIARHSQIPVVADIHFQPRYIFAAIDAGCAAVRVNPGN 120 TAAGCDIVRVACP Q+DADAL IA+ SQIPV+ADIHFQP+Y++AAIDAGCAAVRVNPGN Sbjct 61 TAAGCDIVRVACPSQDDADALPAIAQKSQIPVIADIHFQPKYVYAAIDAGCAAVRVNPGN 120 Query 121 IKEFDGRVGEVAKAAGAAGIPIRIGVNAGSLDKRFMEKYGKATPEALVESALWEASLFEE 180 I+EFD +VGE+A+ A AG+ IRIGVNAGSLD+R + KYG+ATPEALVESA+WEASLFEE Sbjct 121 IREFDDQVGEIARRAKEAGVSIRIGVNAGSLDRRLLAKYGRATPEALVESAVWEASLFEE 180 Query 181 HGFGDIKISVKHNDPVVMVAAYELLAARCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSR 240 H F D KISVKHNDPV MV AYELLA R D+PLHLGVTEAGPAFQGTIKSA AFGALLS+ Sbjct 181 HDFHDFKISVKHNDPVTMVRAYELLAERGDWPLHLGVTEAGPAFQGTIKSATAFGALLSK 240 Query 241 GIGDTIRVSLSAPPVEEVKVGNQVLESLNLRPRSLEIVSCPSCGRAQVDVYTLANEVTAG 300 GIGDTIRVSLSAPPVEEVKVG+Q+L SL LRPR LEIVSCPSCGRAQVDVYTLA +VTAG Sbjct 241 GIGDTIRVSLSAPPVEEVKVGSQILMSLGLRPRKLEIVSCPSCGRAQVDVYTLAEQVTAG 300 Query 301 LDGLDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPEAQIVETLIE 360 L+GL VPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFV+GEVIKTVPE+QIVETLIE Sbjct 301 LEGLTVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVKGEVIKTVPESQIVETLIE 360 Query 361 EAMRLAAEMGEQDPGATPSGSPIVTV 386 EAMRLA EMGE + +G+P VTV Sbjct 361 EAMRLAEEMGEPVDEES-AGNPTVTV 385 >gi|325962793|ref|YP_004240699.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Arthrobacter phenanthrenivorans Sphe3] gi|323468880|gb|ADX72565.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Arthrobacter phenanthrenivorans Sphe3] Length=388 Score = 629 bits (1623), Expect = 2e-178, Method: Compositional matrix adjust. Identities = 306/386 (80%), Positives = 344/386 (90%), Gaps = 0/386 (0%) Query 2 TVGLGMPQPPAPTLAPRRATRQLMVGNVGVGSDHPVSVQSMCTTKTHDVNSTLQQIAELT 61 +V LGMP P P LAPRR TRQ+ VG+VGVGSD P+SVQSM TT T D+N+TLQQIAELT Sbjct 3 SVSLGMPSAPPPVLAPRRKTRQIKVGSVGVGSDSPISVQSMTTTPTTDINATLQQIAELT 62 Query 62 AAGCDIVRVACPRQEDADALAEIARHSQIPVVADIHFQPRYIFAAIDAGCAAVRVNPGNI 121 A+GCDIVRVACP +DA+AL IAR SQIPV+ADIHFQP+Y+FAAI+AGCAAVRVNPGNI Sbjct 63 ASGCDIVRVACPSADDAEALPIIARKSQIPVIADIHFQPKYVFAAIEAGCAAVRVNPGNI 122 Query 122 KEFDGRVGEVAKAAGAAGIPIRIGVNAGSLDKRFMEKYGKATPEALVESALWEASLFEEH 181 ++FD +V E+A AA G IRIGVNAGSL+ ++KYGKATPEALVESA+WEASLFEEH Sbjct 123 RKFDDQVKEIAAAARDHGTSIRIGVNAGSLEPGILKKYGKATPEALVESAVWEASLFEEH 182 Query 182 GFGDIKISVKHNDPVVMVAAYELLAARCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSRG 241 GF D KISVKHNDPV+MVAAYE+LA + D+PLHLGVTEAGPAFQGTIKSA AFGALLSRG Sbjct 183 GFHDFKISVKHNDPVIMVAAYEMLAEKGDWPLHLGVTEAGPAFQGTIKSATAFGALLSRG 242 Query 242 IGDTIRVSLSAPPVEEVKVGNQVLESLNLRPRSLEIVSCPSCGRAQVDVYTLANEVTAGL 301 IGDTIRVSLSAPPVEE+KVGNQ+L+SLNLRPR LEIVSCPSCGRAQVDVYTLA +VTAGL Sbjct 243 IGDTIRVSLSAPPVEEIKVGNQILQSLNLRPRKLEIVSCPSCGRAQVDVYTLAEQVTAGL 302 Query 302 DGLDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPEAQIVETLIEE 361 +G+++PLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFV+GEVIKTVPE+QIVETLIEE Sbjct 303 EGMEIPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVKGEVIKTVPESQIVETLIEE 362 Query 362 AMRLAAEMGEQDPGATPSGSPIVTVS 387 AMR+A EMGE D GSP+V+VS Sbjct 363 AMRIAEEMGEADGEDAVKGSPVVSVS 388 >gi|116669965|ref|YP_830898.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Arthrobacter sp. FB24] gi|166216864|sp|A0JUS8.1|ISPG_ARTS2 RecName: Full=4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; AltName: Full=1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase gi|116610074|gb|ABK02798.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Arthrobacter sp. FB24] Length=388 Score = 629 bits (1622), Expect = 2e-178, Method: Compositional matrix adjust. Identities = 305/386 (80%), Positives = 345/386 (90%), Gaps = 0/386 (0%) Query 2 TVGLGMPQPPAPTLAPRRATRQLMVGNVGVGSDHPVSVQSMCTTKTHDVNSTLQQIAELT 61 +V LGMP P P LAPRR TRQ+ VG+VGVGSD P+SVQSM TT T D+N+TLQQIAELT Sbjct 3 SVSLGMPSAPPPVLAPRRKTRQIKVGSVGVGSDSPISVQSMTTTPTTDINATLQQIAELT 62 Query 62 AAGCDIVRVACPRQEDADALAEIARHSQIPVVADIHFQPRYIFAAIDAGCAAVRVNPGNI 121 A+GCDIVRVACP +DA+AL IAR SQIPV+ADIHFQP+Y+FAAI+AGCAAVRVNPGNI Sbjct 63 ASGCDIVRVACPSADDAEALPIIARKSQIPVIADIHFQPKYVFAAIEAGCAAVRVNPGNI 122 Query 122 KEFDGRVGEVAKAAGAAGIPIRIGVNAGSLDKRFMEKYGKATPEALVESALWEASLFEEH 181 ++FD +V E+A+AA G IRIGVNAGSL+ ++KYGKATPEALVESA+WEASLFEEH Sbjct 123 RKFDDQVKEIARAAKDHGTSIRIGVNAGSLEPGILKKYGKATPEALVESAVWEASLFEEH 182 Query 182 GFGDIKISVKHNDPVVMVAAYELLAARCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSRG 241 GF D KISVKHNDPV+MVAAYE+LA + D+PLHLGVTEAGPAFQGTIKSA AFGALLSRG Sbjct 183 GFHDFKISVKHNDPVIMVAAYEMLAEKGDWPLHLGVTEAGPAFQGTIKSATAFGALLSRG 242 Query 242 IGDTIRVSLSAPPVEEVKVGNQVLESLNLRPRSLEIVSCPSCGRAQVDVYTLANEVTAGL 301 IGDTIRVSLSAPPVEE+KVGNQ+L+SLNLRPR LEIVSCPSCGRAQVDVYTLA +VTAGL Sbjct 243 IGDTIRVSLSAPPVEEIKVGNQILQSLNLRPRKLEIVSCPSCGRAQVDVYTLAEQVTAGL 302 Query 302 DGLDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPEAQIVETLIEE 361 +G+++PLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFV+GEVIKTVPE++IVETLIEE Sbjct 303 EGMEIPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVKGEVIKTVPESEIVETLIEE 362 Query 362 AMRLAAEMGEQDPGATPSGSPIVTVS 387 AMR+A EMGE D GSP+V+VS Sbjct 363 AMRIAEEMGEADGEDAVKGSPVVSVS 388 >gi|302525241|ref|ZP_07277583.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Streptomyces sp. AA4] gi|302434136|gb|EFL05952.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Streptomyces sp. AA4] Length=383 Score = 628 bits (1620), Expect = 4e-178, Method: Compositional matrix adjust. Identities = 307/379 (82%), Positives = 339/379 (90%), Gaps = 0/379 (0%) Query 1 VTVGLGMPQPPAPTLAPRRATRQLMVGNVGVGSDHPVSVQSMCTTKTHDVNSTLQQIAEL 60 +TV LGMP P P L+ RR TRQLMVG+VGVGSDHP+SVQSM TT T DVN+TLQQIAEL Sbjct 1 MTVALGMPALPPPVLSERRKTRQLMVGSVGVGSDHPISVQSMTTTLTSDVNATLQQIAEL 60 Query 61 TAAGCDIVRVACPRQEDADALAEIARHSQIPVVADIHFQPRYIFAAIDAGCAAVRVNPGN 120 TAAGCDIVRVACP +DA+AL IA+ SQIPV+ADIHFQP+Y+FAAI+AGCAAVRVNPGN Sbjct 61 TAAGCDIVRVACPSADDAEALPAIAKKSQIPVIADIHFQPKYVFAAIEAGCAAVRVNPGN 120 Query 121 IKEFDGRVGEVAKAAGAAGIPIRIGVNAGSLDKRFMEKYGKATPEALVESALWEASLFEE 180 I++FD +V E+A+AA G PIRIGVNAGSLDKR +EKYGKATPEAL ESA+WEASLF E Sbjct 121 IRKFDDQVKEIAQAAKDHGTPIRIGVNAGSLDKRLLEKYGKATPEALAESAMWEASLFAE 180 Query 181 HGFGDIKISVKHNDPVVMVAAYELLAARCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSR 240 H F DIKISVKHNDPVVMV AYE+LA +CDYPLHLGVTEAGPAFQGTIKSAVAFGALL + Sbjct 181 HDFHDIKISVKHNDPVVMVRAYEILAEQCDYPLHLGVTEAGPAFQGTIKSAVAFGALLRQ 240 Query 241 GIGDTIRVSLSAPPVEEVKVGNQVLESLNLRPRSLEIVSCPSCGRAQVDVYTLANEVTAG 300 GIGDTIRVSLSAPPVEEVKVG Q+L+SLNLRPR LEIVSCPSCGRAQVDVYTLA++VTAG Sbjct 241 GIGDTIRVSLSAPPVEEVKVGAQILQSLNLRPRKLEIVSCPSCGRAQVDVYTLADQVTAG 300 Query 301 LDGLDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPEAQIVETLIE 360 L+G+++PLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFV+GEVIKTVPE IVETLIE Sbjct 301 LEGMEIPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVKGEVIKTVPEHAIVETLIE 360 Query 361 EAMRLAAEMGEQDPGATPS 379 EAMR+A E GE TPS Sbjct 361 EAMRIAEESGESIGEGTPS 379 >gi|305681127|ref|ZP_07403934.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Corynebacterium matruchotii ATCC 14266] gi|305659332|gb|EFM48832.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Corynebacterium matruchotii ATCC 14266] Length=374 Score = 628 bits (1620), Expect = 4e-178, Method: Compositional matrix adjust. Identities = 306/358 (86%), Positives = 330/358 (93%), Gaps = 0/358 (0%) Query 13 PTLAPRRATRQLMVGNVGVGSDHPVSVQSMCTTKTHDVNSTLQQIAELTAAGCDIVRVAC 72 P LAPRR TRQLMVG+VGVGSD+PVSVQSM TTKTHD+N+TLQQIA+LTA+GCDIVRVAC Sbjct 2 PVLAPRRKTRQLMVGSVGVGSDYPVSVQSMTTTKTHDINATLQQIAQLTASGCDIVRVAC 61 Query 73 PRQEDADALAEIARHSQIPVVADIHFQPRYIFAAIDAGCAAVRVNPGNIKEFDGRVGEVA 132 P+ DADAL IA+ S IPV+ADIHFQP+YIFAAIDAGCAAVRVNPGNIKEFDGRV EVA Sbjct 62 PKPIDADALPTIAKKSPIPVIADIHFQPKYIFAAIDAGCAAVRVNPGNIKEFDGRVKEVA 121 Query 133 KAAGAAGIPIRIGVNAGSLDKRFMEKYGKATPEALVESALWEASLFEEHGFGDIKISVKH 192 AA AGIPIRIGVNAGSLDKR + KYGKATPEALVESALWEASLFEEHGFGDIKISVKH Sbjct 122 HAARDAGIPIRIGVNAGSLDKRLLAKYGKATPEALVESALWEASLFEEHGFGDIKISVKH 181 Query 193 NDPVVMVAAYELLAARCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSRGIGDTIRVSLSA 252 NDPV+MV+AY LA +CDYPLHLGVTEAGPAFQGTIKSAVAFGALLS GIGDTIRVSLSA Sbjct 182 NDPVIMVSAYRQLAEQCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSEGIGDTIRVSLSA 241 Query 253 PPVEEVKVGNQVLESLNLRPRSLEIVSCPSCGRAQVDVYTLANEVTAGLDGLDVPLRVAV 312 P EEVKVG+Q+L+SLNLR R LEIVSCPSCGRAQVDVYTLA EVTA LDG+D+P RVAV Sbjct 242 DPKEEVKVGDQILQSLNLRERGLEIVSCPSCGRAQVDVYTLAEEVTAALDGMDIPFRVAV 301 Query 313 MGCVVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPEAQIVETLIEEAMRLAAEMG 370 MGCVVNGPGEAR+ADLGVASGNGKGQIFV+GEVIKTVPE+QIVETLIEEA++LA E G Sbjct 302 MGCVVNGPGEARDADLGVASGNGKGQIFVKGEVIKTVPESQIVETLIEEAIKLAEEQG 359 Lambda K H 0.317 0.134 0.389 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 755833905300 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40