BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv2914c Length=585 Score E Sequences producing significant alignments: (Bits) Value gi|15610051|ref|NP_217430.1| transmembrane serine/threonine-prot... 1177 0.0 gi|15842457|ref|NP_337494.1| serine/threonine protein kinase [My... 1176 0.0 gi|167969543|ref|ZP_02551820.1| transmembrane serine/threonine-p... 1175 0.0 gi|306808883|ref|ZP_07445551.1| transmembrane serine/threonine-p... 1170 0.0 gi|240170564|ref|ZP_04749223.1| putative transmembrane serine/th... 643 0.0 gi|183981807|ref|YP_001850098.1| transmembrane serine/threonine-... 545 1e-152 gi|118617616|ref|YP_905948.1| transmembrane serine/threonine-pro... 535 7e-150 gi|342858235|ref|ZP_08714890.1| PknF [Mycobacterium colombiense ... 482 8e-134 gi|342860791|ref|ZP_08717441.1| PknF protein [Mycobacterium colo... 379 9e-103 gi|296164508|ref|ZP_06847079.1| non-specific serine/threonine pr... 287 4e-75 gi|41407430|ref|NP_960266.1| PknF [Mycobacterium avium subsp. pa... 285 2e-74 gi|336457782|gb|EGO36776.1| serine/threonine protein kinase [Myc... 284 3e-74 gi|254775595|ref|ZP_05217111.1| PknF protein [Mycobacterium aviu... 284 3e-74 gi|333989985|ref|YP_004522599.1| anchored-membrane serine/threon... 283 4e-74 gi|254820994|ref|ZP_05225995.1| PknF protein [Mycobacterium intr... 283 6e-74 gi|126437262|ref|YP_001072953.1| protein kinase [Mycobacterium s... 280 4e-73 gi|118462529|ref|YP_882329.1| PknF protein [Mycobacterium avium ... 280 6e-73 gi|240172042|ref|ZP_04750701.1| anchored-membrane serine/threoni... 278 2e-72 gi|118468993|ref|YP_889750.1| serine/threonine protein kinase [M... 276 6e-72 gi|240172658|ref|ZP_04751317.1| anchored-membrane serine/threoni... 276 8e-72 gi|118473542|ref|YP_887980.1| serine/threonine protein kinase [M... 275 1e-71 gi|118471062|ref|YP_885289.1| serine/threonine protein kinase [M... 272 2e-70 gi|145224013|ref|YP_001134691.1| protein kinase [Mycobacterium g... 271 3e-70 gi|120406577|ref|YP_956406.1| protein kinase [Mycobacterium vanb... 271 3e-70 gi|183982616|ref|YP_001850907.1| anchored-membrane serine/threon... 270 7e-70 gi|315444348|ref|YP_004077227.1| serine/threonine protein kinase... 270 7e-70 gi|240167979|ref|ZP_04746638.1| anchored-membrane serine/threoni... 270 8e-70 gi|240172044|ref|ZP_04750703.1| anchored-membrane serine/threoni... 269 9e-70 gi|108801281|ref|YP_641478.1| serine/threonine protein kinase [M... 269 9e-70 gi|183982944|ref|YP_001851235.1| membrane-anchored serine/threon... 268 1e-69 gi|118617740|ref|YP_906072.1| membrane-anchored serine/threonine... 266 7e-69 gi|31792934|ref|NP_855427.1| anchored-membrane serine/threonine-... 265 1e-68 gi|15608884|ref|NP_216262.1| anchored-membrane serine/threonine-... 265 1e-68 gi|126437951|ref|YP_001073642.1| serine/threonine protein kinase... 265 2e-68 gi|108801970|ref|YP_642167.1| serine/threonine protein kinase [M... 265 2e-68 gi|183984145|ref|YP_001852436.1| anchored-membrane serine/threon... 264 3e-68 gi|118472741|ref|YP_885582.1| serine/threonine protein kinase [M... 264 4e-68 gi|342860823|ref|ZP_08717473.1| anchored-membrane serine/threoni... 261 3e-67 gi|183982422|ref|YP_001850713.1| anchored-membrane serine/threon... 260 4e-67 gi|118619584|ref|YP_907916.1| anchored-membrane serine/threonine... 259 1e-66 gi|240172797|ref|ZP_04751456.1| serine/threonine-protein kinase ... 256 5e-66 gi|289750305|ref|ZP_06509683.1| serine/threonine protein kinase ... 255 1e-65 gi|240173245|ref|ZP_04751903.1| anchored-membrane serine/threoni... 254 2e-65 gi|240172043|ref|ZP_04750702.1| anchored-membrane serine/threoni... 254 4e-65 gi|126433399|ref|YP_001069090.1| protein kinase [Mycobacterium s... 253 5e-65 gi|108797772|ref|YP_637969.1| serine/threonine protein kinase [M... 253 6e-65 gi|240168646|ref|ZP_04747305.1| membrane-anchored serine/threoni... 253 6e-65 gi|169245915|gb|ACA50936.1| transmembrane serine/threonine-prote... 253 1e-64 gi|315446500|ref|YP_004079379.1| serine/threonine protein kinase... 250 6e-64 gi|145221764|ref|YP_001132442.1| protein kinase [Mycobacterium g... 250 6e-64 >gi|15610051|ref|NP_217430.1| transmembrane serine/threonine-protein kinase I [Mycobacterium tuberculosis H37Rv] gi|31794090|ref|NP_856583.1| transmembrane serine/threonine-protein kinase I [Mycobacterium bovis AF2122/97] gi|121638795|ref|YP_979019.1| putative transmembrane serine/threonine-protein kinase I pknI [Mycobacterium bovis BCG str. Pasteur 1173P2] 75 more sequence titles Length=585 Score = 1177 bits (3045), Expect = 0.0, Method: Compositional matrix adjust. Identities = 585/585 (100%), Positives = 585/585 (100%), Gaps = 0/585 (0%) Query 1 MALASGVTFAGYTVVRMLGCSAMGEVYLVQHPGFPGWQALKVLSPAMAADDEFRRRFQRE 60 MALASGVTFAGYTVVRMLGCSAMGEVYLVQHPGFPGWQALKVLSPAMAADDEFRRRFQRE Sbjct 1 MALASGVTFAGYTVVRMLGCSAMGEVYLVQHPGFPGWQALKVLSPAMAADDEFRRRFQRE 60 Query 61 TEVAARLFHPHILEVHDRGEFDGQLWIAMDYVDGIDATQHMADRFPAVLPVGEVLAIVTA 120 TEVAARLFHPHILEVHDRGEFDGQLWIAMDYVDGIDATQHMADRFPAVLPVGEVLAIVTA Sbjct 61 TEVAARLFHPHILEVHDRGEFDGQLWIAMDYVDGIDATQHMADRFPAVLPVGEVLAIVTA 120 Query 121 VAGALDYAHQRGLLHRDVNPANVVLTSQSAGDQRILLADFGIASQPSYPAPELSAGADVD 180 VAGALDYAHQRGLLHRDVNPANVVLTSQSAGDQRILLADFGIASQPSYPAPELSAGADVD Sbjct 121 VAGALDYAHQRGLLHRDVNPANVVLTSQSAGDQRILLADFGIASQPSYPAPELSAGADVD 180 Query 181 GRADQYALALTAIHLFAGAPPVDRSHTGPLQPPKLSAFRPDLARLDGVLSRALATAPADR 240 GRADQYALALTAIHLFAGAPPVDRSHTGPLQPPKLSAFRPDLARLDGVLSRALATAPADR Sbjct 181 GRADQYALALTAIHLFAGAPPVDRSHTGPLQPPKLSAFRPDLARLDGVLSRALATAPADR 240 Query 241 FGSCREFADAMNEQAGVAIADQSSGGVDASEVTAAAGEEAYVVDYPAYGWPEAVDCKEPS 300 FGSCREFADAMNEQAGVAIADQSSGGVDASEVTAAAGEEAYVVDYPAYGWPEAVDCKEPS Sbjct 241 FGSCREFADAMNEQAGVAIADQSSGGVDASEVTAAAGEEAYVVDYPAYGWPEAVDCKEPS 300 Query 301 ARAPAPAAPTPQRRGSMLQSAAGVLARRLDNFSTATKAPASPTRRRPRRILVGAVAVLLL 360 ARAPAPAAPTPQRRGSMLQSAAGVLARRLDNFSTATKAPASPTRRRPRRILVGAVAVLLL Sbjct 301 ARAPAPAAPTPQRRGSMLQSAAGVLARRLDNFSTATKAPASPTRRRPRRILVGAVAVLLL 360 Query 361 AGLFAVGIVIGRKTNTTATEVARPPTSGSAVPSAPTTTVAVTAPVPLDGTYRIEIQRSKQ 420 AGLFAVGIVIGRKTNTTATEVARPPTSGSAVPSAPTTTVAVTAPVPLDGTYRIEIQRSKQ Sbjct 361 AGLFAVGIVIGRKTNTTATEVARPPTSGSAVPSAPTTTVAVTAPVPLDGTYRIEIQRSKQ 420 Query 421 TYDYTPTPQPPDVNTWWAFRTSCTPTECLAAATMLDDNDHTQAKTPPVRPFLMQFGEGQW 480 TYDYTPTPQPPDVNTWWAFRTSCTPTECLAAATMLDDNDHTQAKTPPVRPFLMQFGEGQW Sbjct 421 TYDYTPTPQPPDVNTWWAFRTSCTPTECLAAATMLDDNDHTQAKTPPVRPFLMQFGEGQW 480 Query 481 KSRPETVQFPCVGPNGSPSTQATTQLLALRPQPQGDLVGEMVVTVHSNECGQQGAVIRIP 540 KSRPETVQFPCVGPNGSPSTQATTQLLALRPQPQGDLVGEMVVTVHSNECGQQGAVIRIP Sbjct 481 KSRPETVQFPCVGPNGSPSTQATTQLLALRPQPQGDLVGEMVVTVHSNECGQQGAVIRIP 540 Query 541 AVASRSGDLPPAVTVPDPATIPDTPDTTSTATLTPPTTTAPGPGR 585 AVASRSGDLPPAVTVPDPATIPDTPDTTSTATLTPPTTTAPGPGR Sbjct 541 AVASRSGDLPPAVTVPDPATIPDTPDTTSTATLTPPTTTAPGPGR 585 >gi|15842457|ref|NP_337494.1| serine/threonine protein kinase [Mycobacterium tuberculosis CDC1551] gi|313659863|ref|ZP_07816743.1| transmembrane serine/threonine-protein kinase I PknI [Mycobacterium tuberculosis KZN V2475] gi|13882761|gb|AAK47308.1| serine/threonine protein kinase [Mycobacterium tuberculosis CDC1551] Length=603 Score = 1176 bits (3043), Expect = 0.0, Method: Compositional matrix adjust. Identities = 585/585 (100%), Positives = 585/585 (100%), Gaps = 0/585 (0%) Query 1 MALASGVTFAGYTVVRMLGCSAMGEVYLVQHPGFPGWQALKVLSPAMAADDEFRRRFQRE 60 MALASGVTFAGYTVVRMLGCSAMGEVYLVQHPGFPGWQALKVLSPAMAADDEFRRRFQRE Sbjct 19 MALASGVTFAGYTVVRMLGCSAMGEVYLVQHPGFPGWQALKVLSPAMAADDEFRRRFQRE 78 Query 61 TEVAARLFHPHILEVHDRGEFDGQLWIAMDYVDGIDATQHMADRFPAVLPVGEVLAIVTA 120 TEVAARLFHPHILEVHDRGEFDGQLWIAMDYVDGIDATQHMADRFPAVLPVGEVLAIVTA Sbjct 79 TEVAARLFHPHILEVHDRGEFDGQLWIAMDYVDGIDATQHMADRFPAVLPVGEVLAIVTA 138 Query 121 VAGALDYAHQRGLLHRDVNPANVVLTSQSAGDQRILLADFGIASQPSYPAPELSAGADVD 180 VAGALDYAHQRGLLHRDVNPANVVLTSQSAGDQRILLADFGIASQPSYPAPELSAGADVD Sbjct 139 VAGALDYAHQRGLLHRDVNPANVVLTSQSAGDQRILLADFGIASQPSYPAPELSAGADVD 198 Query 181 GRADQYALALTAIHLFAGAPPVDRSHTGPLQPPKLSAFRPDLARLDGVLSRALATAPADR 240 GRADQYALALTAIHLFAGAPPVDRSHTGPLQPPKLSAFRPDLARLDGVLSRALATAPADR Sbjct 199 GRADQYALALTAIHLFAGAPPVDRSHTGPLQPPKLSAFRPDLARLDGVLSRALATAPADR 258 Query 241 FGSCREFADAMNEQAGVAIADQSSGGVDASEVTAAAGEEAYVVDYPAYGWPEAVDCKEPS 300 FGSCREFADAMNEQAGVAIADQSSGGVDASEVTAAAGEEAYVVDYPAYGWPEAVDCKEPS Sbjct 259 FGSCREFADAMNEQAGVAIADQSSGGVDASEVTAAAGEEAYVVDYPAYGWPEAVDCKEPS 318 Query 301 ARAPAPAAPTPQRRGSMLQSAAGVLARRLDNFSTATKAPASPTRRRPRRILVGAVAVLLL 360 ARAPAPAAPTPQRRGSMLQSAAGVLARRLDNFSTATKAPASPTRRRPRRILVGAVAVLLL Sbjct 319 ARAPAPAAPTPQRRGSMLQSAAGVLARRLDNFSTATKAPASPTRRRPRRILVGAVAVLLL 378 Query 361 AGLFAVGIVIGRKTNTTATEVARPPTSGSAVPSAPTTTVAVTAPVPLDGTYRIEIQRSKQ 420 AGLFAVGIVIGRKTNTTATEVARPPTSGSAVPSAPTTTVAVTAPVPLDGTYRIEIQRSKQ Sbjct 379 AGLFAVGIVIGRKTNTTATEVARPPTSGSAVPSAPTTTVAVTAPVPLDGTYRIEIQRSKQ 438 Query 421 TYDYTPTPQPPDVNTWWAFRTSCTPTECLAAATMLDDNDHTQAKTPPVRPFLMQFGEGQW 480 TYDYTPTPQPPDVNTWWAFRTSCTPTECLAAATMLDDNDHTQAKTPPVRPFLMQFGEGQW Sbjct 439 TYDYTPTPQPPDVNTWWAFRTSCTPTECLAAATMLDDNDHTQAKTPPVRPFLMQFGEGQW 498 Query 481 KSRPETVQFPCVGPNGSPSTQATTQLLALRPQPQGDLVGEMVVTVHSNECGQQGAVIRIP 540 KSRPETVQFPCVGPNGSPSTQATTQLLALRPQPQGDLVGEMVVTVHSNECGQQGAVIRIP Sbjct 499 KSRPETVQFPCVGPNGSPSTQATTQLLALRPQPQGDLVGEMVVTVHSNECGQQGAVIRIP 558 Query 541 AVASRSGDLPPAVTVPDPATIPDTPDTTSTATLTPPTTTAPGPGR 585 AVASRSGDLPPAVTVPDPATIPDTPDTTSTATLTPPTTTAPGPGR Sbjct 559 AVASRSGDLPPAVTVPDPATIPDTPDTTSTATLTPPTTTAPGPGR 603 >gi|167969543|ref|ZP_02551820.1| transmembrane serine/threonine-protein kinase I pknI [Mycobacterium tuberculosis H37Ra] Length=585 Score = 1175 bits (3039), Expect = 0.0, Method: Compositional matrix adjust. Identities = 584/585 (99%), Positives = 584/585 (99%), Gaps = 0/585 (0%) Query 1 MALASGVTFAGYTVVRMLGCSAMGEVYLVQHPGFPGWQALKVLSPAMAADDEFRRRFQRE 60 MALASGVTFAGYTVVRMLGCSAMGEVYLVQHPGFPGWQALKVLSPAMAADDEFRRRFQRE Sbjct 1 MALASGVTFAGYTVVRMLGCSAMGEVYLVQHPGFPGWQALKVLSPAMAADDEFRRRFQRE 60 Query 61 TEVAARLFHPHILEVHDRGEFDGQLWIAMDYVDGIDATQHMADRFPAVLPVGEVLAIVTA 120 TEVAARLFHPHILEVHDRGEFDGQLWIAMDYVDGIDATQHMADRFPAVLPVGEVLAIVTA Sbjct 61 TEVAARLFHPHILEVHDRGEFDGQLWIAMDYVDGIDATQHMADRFPAVLPVGEVLAIVTA 120 Query 121 VAGALDYAHQRGLLHRDVNPANVVLTSQSAGDQRILLADFGIASQPSYPAPELSAGADVD 180 VAGALDYAHQRGLLHRDVNPANVVLTSQSAGDQRILLADFGIASQPSYPAPELSAGADVD Sbjct 121 VAGALDYAHQRGLLHRDVNPANVVLTSQSAGDQRILLADFGIASQPSYPAPELSAGADVD 180 Query 181 GRADQYALALTAIHLFAGAPPVDRSHTGPLQPPKLSAFRPDLARLDGVLSRALATAPADR 240 GRADQYALALTAIHLFAGAPPVDRSHTGPLQPPKLSAFRPDLARLDGVLSRALATAPADR Sbjct 181 GRADQYALALTAIHLFAGAPPVDRSHTGPLQPPKLSAFRPDLARLDGVLSRALATAPADR 240 Query 241 FGSCREFADAMNEQAGVAIADQSSGGVDASEVTAAAGEEAYVVDYPAYGWPEAVDCKEPS 300 FGSCREFADAMNEQAGVAIADQSSGGVDASEVTAAAGEEAYVVDYPAYGWPEAVDCKEPS Sbjct 241 FGSCREFADAMNEQAGVAIADQSSGGVDASEVTAAAGEEAYVVDYPAYGWPEAVDCKEPS 300 Query 301 ARAPAPAAPTPQRRGSMLQSAAGVLARRLDNFSTATKAPASPTRRRPRRILVGAVAVLLL 360 ARAPAPAAPTPQRRGSMLQSAAGVLARR DNFSTATKAPASPTRRRPRRILVGAVAVLLL Sbjct 301 ARAPAPAAPTPQRRGSMLQSAAGVLARRXDNFSTATKAPASPTRRRPRRILVGAVAVLLL 360 Query 361 AGLFAVGIVIGRKTNTTATEVARPPTSGSAVPSAPTTTVAVTAPVPLDGTYRIEIQRSKQ 420 AGLFAVGIVIGRKTNTTATEVARPPTSGSAVPSAPTTTVAVTAPVPLDGTYRIEIQRSKQ Sbjct 361 AGLFAVGIVIGRKTNTTATEVARPPTSGSAVPSAPTTTVAVTAPVPLDGTYRIEIQRSKQ 420 Query 421 TYDYTPTPQPPDVNTWWAFRTSCTPTECLAAATMLDDNDHTQAKTPPVRPFLMQFGEGQW 480 TYDYTPTPQPPDVNTWWAFRTSCTPTECLAAATMLDDNDHTQAKTPPVRPFLMQFGEGQW Sbjct 421 TYDYTPTPQPPDVNTWWAFRTSCTPTECLAAATMLDDNDHTQAKTPPVRPFLMQFGEGQW 480 Query 481 KSRPETVQFPCVGPNGSPSTQATTQLLALRPQPQGDLVGEMVVTVHSNECGQQGAVIRIP 540 KSRPETVQFPCVGPNGSPSTQATTQLLALRPQPQGDLVGEMVVTVHSNECGQQGAVIRIP Sbjct 481 KSRPETVQFPCVGPNGSPSTQATTQLLALRPQPQGDLVGEMVVTVHSNECGQQGAVIRIP 540 Query 541 AVASRSGDLPPAVTVPDPATIPDTPDTTSTATLTPPTTTAPGPGR 585 AVASRSGDLPPAVTVPDPATIPDTPDTTSTATLTPPTTTAPGPGR Sbjct 541 AVASRSGDLPPAVTVPDPATIPDTPDTTSTATLTPPTTTAPGPGR 585 >gi|306808883|ref|ZP_07445551.1| transmembrane serine/threonine-protein kinase I pknI [Mycobacterium tuberculosis SUMu007] gi|308344835|gb|EFP33686.1| transmembrane serine/threonine-protein kinase I pknI [Mycobacterium tuberculosis SUMu007] Length=585 Score = 1170 bits (3026), Expect = 0.0, Method: Compositional matrix adjust. Identities = 581/585 (99%), Positives = 581/585 (99%), Gaps = 0/585 (0%) Query 1 MALASGVTFAGYTVVRMLGCSAMGEVYLVQHPGFPGWQALKVLSPAMAADDEFRRRFQRE 60 MALASGVTFAGYTVVRMLGCSAMGEVYLVQHPGFPGWQALKVLSPAMAADDEFRRRFQRE Sbjct 1 MALASGVTFAGYTVVRMLGCSAMGEVYLVQHPGFPGWQALKVLSPAMAADDEFRRRFQRE 60 Query 61 TEVAARLFHPHILEVHDRGEFDGQLWIAMDYVDGIDATQHMADRFPAVLPVGEVLAIVTA 120 TEVAARLFHPHILEVHDRGEFDGQLWIAMDYVDGIDATQHMADRFPAVLPVGEVLAIVTA Sbjct 61 TEVAARLFHPHILEVHDRGEFDGQLWIAMDYVDGIDATQHMADRFPAVLPVGEVLAIVTA 120 Query 121 VAGALDYAHQRGLLHRDVNPANVVLTSQSAGDQRILLADFGIASQPSYPAPELSAGADVD 180 VAGALDYAHQRGLLHRDVNPANVVLTSQSAGDQRILLADFGIASQPSYPAPELSAGADVD Sbjct 121 VAGALDYAHQRGLLHRDVNPANVVLTSQSAGDQRILLADFGIASQPSYPAPELSAGADVD 180 Query 181 GRADQYALALTAIHLFAGAPPVDRSHTGPLQPPKLSAFRPDLARLDGVLSRALATAPADR 240 GRADQYALALTAIHLFAGAPPVDRSHTGPLQPPKLSAFRPDLARLDGVLSRALATAPADR Sbjct 181 GRADQYALALTAIHLFAGAPPVDRSHTGPLQPPKLSAFRPDLARLDGVLSRALATAPADR 240 Query 241 FGSCREFADAMNEQAGVAIADQSSGGVDASEVTAAAGEEAYVVDYPAYGWPEAVDCKEPS 300 FGSCREFADAMNEQAGVAIADQSSGGVDASEVTAAAGEEAYVVDYPAYGWPEAVDCKEPS Sbjct 241 FGSCREFADAMNEQAGVAIADQSSGGVDASEVTAAAGEEAYVVDYPAYGWPEAVDCKEPS 300 Query 301 ARAPAPAAPTPQRRGSMLQSAAGVLARRLDNFSTATKAPASPTRRRPRRILVGAVAVLLL 360 ARAP PTPQRRGSMLQSAAGVLARRLDNFSTATKAPASPTRRRPRRILVGAVAVLLL Sbjct 301 ARAPGAGGPTPQRRGSMLQSAAGVLARRLDNFSTATKAPASPTRRRPRRILVGAVAVLLL 360 Query 361 AGLFAVGIVIGRKTNTTATEVARPPTSGSAVPSAPTTTVAVTAPVPLDGTYRIEIQRSKQ 420 AGLFAVGIVIGRKTNTTATEVARPPTSGSAVPSAPTTTVAVTAPVPLDGTYRIEIQRSKQ Sbjct 361 AGLFAVGIVIGRKTNTTATEVARPPTSGSAVPSAPTTTVAVTAPVPLDGTYRIEIQRSKQ 420 Query 421 TYDYTPTPQPPDVNTWWAFRTSCTPTECLAAATMLDDNDHTQAKTPPVRPFLMQFGEGQW 480 TYDYTPTPQPPDVNTWWAFRTSCTPTECLAAATMLDDNDHTQAKTPPVRPFLMQFGEGQW Sbjct 421 TYDYTPTPQPPDVNTWWAFRTSCTPTECLAAATMLDDNDHTQAKTPPVRPFLMQFGEGQW 480 Query 481 KSRPETVQFPCVGPNGSPSTQATTQLLALRPQPQGDLVGEMVVTVHSNECGQQGAVIRIP 540 KSRPETVQFPCVGPNGSPSTQATTQLLALRPQPQGDLVGEMVVTVHSNECGQQGAVIRIP Sbjct 481 KSRPETVQFPCVGPNGSPSTQATTQLLALRPQPQGDLVGEMVVTVHSNECGQQGAVIRIP 540 Query 541 AVASRSGDLPPAVTVPDPATIPDTPDTTSTATLTPPTTTAPGPGR 585 AVASRSGDLPPAVTVPDPATIPDTPDTTSTATLTPPTTTAPGPGR Sbjct 541 AVASRSGDLPPAVTVPDPATIPDTPDTTSTATLTPPTTTAPGPGR 585 >gi|240170564|ref|ZP_04749223.1| putative transmembrane serine/threonine-protein kinase I [Mycobacterium kansasii ATCC 12478] Length=565 Score = 643 bits (1658), Expect = 0.0, Method: Compositional matrix adjust. Identities = 366/563 (66%), Positives = 420/563 (75%), Gaps = 19/563 (3%) Query 1 MALASGVTFAGYTVVRMLGCSAMGEVYLVQHPGFPGWQALKVLSPAMAADDEFRRRFQRE 60 MALA G TFA YT+VR+LG GEVYLV+ P ALKVLSPA+++D EFRRRF RE Sbjct 1 MALAGGATFAAYTIVRLLGSGPTGEVYLVEDPRSAQSAALKVLSPALSSDPEFRRRFHRE 60 Query 61 TEVAARLFHPHILEVHDRGEFDGQLWIAMDYVDGIDATQHMADRFPAVLPVGEVLAIVTA 120 T VAA L+HP+I+EVH+RGEF+G+LWIAMDY+DGI A Q M +RFPAVLPVGEVLAI++A Sbjct 61 TAVAANLYHPNIVEVHERGEFEGRLWIAMDYIDGISAAQLMRERFPAVLPVGEVLAIISA 120 Query 121 VAGALDYAHQRGLLHRDVNPANVVLTSQSAGDQRILLADFGIASQPSYPAPELSAGADVD 180 A ALDYAHQR +LH DV PAN+++TS G+ RILL+DFGIA + APE + G + D Sbjct 121 TAAALDYAHQRAVLHGDVKPANILVTSAGPGEPRILLSDFGIAGR----APEQATGTEAD 176 Query 181 GRADQYALALTAIHLFAGAPPVDRSHTGPLQPPKLSAFRPDLARLDGVLSRALATAPADR 240 GRADQYALA TA LF G PVD P KLS RPDLARLD LSRAL+ PA R Sbjct 177 GRADQYALAATAFQLFTGTSPVD-------VPGKLSDLRPDLARLDTALSRALSADPAGR 229 Query 241 FGSCREFADAMNEQAGVAIADQSSGGVDASEVTAAA--GEEAYVVDYPAYGWPEAVDCKE 298 F SCREFADA+NEQAGV DQ VD +AA E AYVVDYP Y WP++ Sbjct 230 FASCREFADALNEQAGVTPVDQRPEVVDPVTAWSAATVAEPAYVVDYPVYDWPQSPPAPP 289 Query 299 PSARAPAPAAPTPQRRGSMLQSAAGVLARRLDNFSTATKAPASPTRRRPRRILVGAVAVL 358 AP P QRRG+ LQSAA LARRLD FS +T+AP +RR RRIL+G+ V+ Sbjct 290 TPPPAPEPV--IQQRRGTPLQSAAAALARRLDAFSRSTQAPG---KRRSRRILLGSAVVV 344 Query 359 LLAGLFAVGIVIGRKTNTTATEVARPPTSGSAVPSAPTTTVAVTAPVPLDGTYRIEIQRS 418 LL GL VGI IGRKT + A P TS S+ S P T+ P PLDGTY+IE+QRS Sbjct 345 LLVGLLGVGIAIGRKTTGDHRQAAGPQTSSSSASSMPATSDPAAPPAPLDGTYQIEVQRS 404 Query 419 KQTYDYTPTPQPPDVNTWWAFRTSCTPTECLAAATMLDDNDHTQAKTPPVRPFLMQFGEG 478 KQTYDYTP+PQPPDVNTWWA R+SCTPT CLAAATMLDDNDHTQAK+ VRP +++FG+G Sbjct 405 KQTYDYTPSPQPPDVNTWWAIRSSCTPTGCLAAATMLDDNDHTQAKS-GVRPLVLEFGQG 463 Query 479 QWKSRPETVQFPCVGPNGSPSTQATTQLLALRPQPQGDLVGEMVVTVHSNECGQQGAVIR 538 QWKSR E VQF C+GPNG+ STQATTQ+L+LRPQP GDLVGEMVVTVHSN+CGQQGAVIR Sbjct 464 QWKSRSEAVQFACIGPNGAASTQATTQVLSLRPQPVGDLVGEMVVTVHSNDCGQQGAVIR 523 Query 539 IPAVASRSGDLPPAVTVPDPATI 561 IPAVASRSGDLPPAV VPDP TI Sbjct 524 IPAVASRSGDLPPAVNVPDPVTI 546 >gi|183981807|ref|YP_001850098.1| transmembrane serine/threonine-protein kinase I PknI [Mycobacterium marinum M] gi|183175133|gb|ACC40243.1| transmembrane serine/threonine-protein kinase I PknI [Mycobacterium marinum M] Length=600 Score = 545 bits (1403), Expect = 1e-152, Method: Compositional matrix adjust. Identities = 314/589 (54%), Positives = 387/589 (66%), Gaps = 30/589 (5%) Query 1 MALASGVTFAGYTVVRMLGCSAMGEVYLVQHPGFPGWQALKVLSPAMAADDEFRRRFQRE 60 MAL +G +AGYTVVR L A GE YLV PGFPGWQ L++L + ++DD FRRRF+R+ Sbjct 1 MALDNGAVYAGYTVVRRLRADATGESYLVSEPGFPGWQVLEILPQSWSSDDAFRRRFERD 60 Query 61 TEVAARLFHPHILEVHDRGEFDGQLWIAMDYVDGIDATQHMADRFPAVLPVGEVLAIVTA 120 + +AARL+HPHI+EV GE DG+LWIAMDY++GID Q M DRFPAVLPVGEVL IV Sbjct 61 SAIAARLYHPHIVEVRAHGELDGRLWIAMDYIEGIDVGQLMRDRFPAVLPVGEVLEIVAP 120 Query 121 VAGALDYAHQRGLLHRDVNPANVVLTSQSAGDQRILLADFGIASQPSYP-------APEL 173 VA ALDYAHQRGL+H DV PA++V+T+ G RILL FGIA+ P APE Sbjct 121 VADALDYAHQRGLVHGDVKPADIVMTNAGEGQPRILLKGFGIAAPHGAPGDATGFVAPEQ 180 Query 174 SAGADVDGRADQYALALTAIHLFAGAPPVDRSHTGPLQPPKLSAFRPDLARLDGVLSRAL 233 GA+ DGR+DQYALA TA+ L GA P S P PKLS RPDLARLD + +RAL Sbjct 181 LTGAEADGRSDQYALAATAMILLTGAAPGGGS---PSAAPKLSDLRPDLARLDALFARAL 237 Query 234 ATAPADRFGSCREFADAMNEQAGVAIADQSSGGVDASEVTAA-----------AGEEAYV 282 AT PA RF +C E ADA+ ++ G + + G D EV A+ A ++ V Sbjct 238 ATEPAGRFRTCHELADALRDEVGGSFG---AAGRDDMEVGASWDLSPDAEATGASQDREV 294 Query 283 VDYPAYGWPEAVDCKEPSARAPAPAAPTPQRRGSMLQSAAGVLARRLDNFSTATKAPASP 342 +DYPAYGWP + P P P AP P ++LQ+ A LARRL+ FS A + P Sbjct 295 LDYPAYGWPAVAPPQPPVHPGPMPMAPQPPA--TLLQAVAASLARRLNEFSAAGREPRKR 352 Query 343 TRRRPRRILVGAVAVLLLAGLFAVGIVIGRKTNTTATEVARPPTSGSAVPSAPTTTVAVT 402 RRIL+G+V +LL G+ AV I R+ ++ A P TS PS T+ Sbjct 353 RL---RRILIGSVVAILLVGMLAVAIPSLREITSSPPPAAAPATSSPPAPSTSATSPQAA 409 Query 403 APVPLDGTYRIEIQRSKQTYDYTPTPQPPDVNTWWAFRTSCTPTECLAAATMLDDNDHTQ 462 P PLDGTY IEIQR+KQ Y+ P+PQPP+V TWWA ++SC PT CLAAA MLD H Q Sbjct 410 TPEPLDGTYSIEIQRAKQLYNGRPSPQPPNVTTWWAIQSSCIPTGCLAAAAMLDGYGHGQ 469 Query 463 AKTPPVRPFLMQFGEGQWKSRPETVQFPCVGPNGSPSTQATTQLLALRPQPQGDLVGEMV 522 AK + P +M+F EGQW+SRP+TV+F C+GPNG +TQ T Q+L LRPQ GDLVG +V Sbjct 470 AKQ-GIPPIIMEFSEGQWRSRPDTVRFACIGPNGEANTQTTVQVLTLRPQSTGDLVGALV 528 Query 523 VTVHSNECGQQGAVIRIPAVASRSGDLPPAVTVPDPATIPDTPDTTSTA 571 VTV +NECGQQ AVIRIPAVASRSGD+PP + VP+P TIP P +T+ Sbjct 529 VTVETNECGQQSAVIRIPAVASRSGDIPPGIKVPNPVTIPKAPQAPATS 577 >gi|118617616|ref|YP_905948.1| transmembrane serine/threonine-protein kinase I PknI [Mycobacterium ulcerans Agy99] gi|118569726|gb|ABL04477.1| transmembrane serine/threonine-protein kinase I PknI [Mycobacterium ulcerans Agy99] Length=601 Score = 535 bits (1379), Expect = 7e-150, Method: Compositional matrix adjust. Identities = 312/590 (53%), Positives = 384/590 (66%), Gaps = 31/590 (5%) Query 1 MALASGVTFAGYTVVRMLGCSAMGEVYLVQHPGFPGWQALKVLSPAMAADDEFRRRFQRE 60 MAL +G +AGYTVVR L A GE YLV PGFPGWQ L++L + ++DD FRRRF+R+ Sbjct 1 MALDNGAVYAGYTVVRRLRADATGESYLVSEPGFPGWQVLEILPQSWSSDDAFRRRFERD 60 Query 61 TEVAARLFHPHILEVHDRGEFDGQLWIAMDYVDGIDATQHMADRFPAVLPVGEVLAIVTA 120 + +AARL+H HI+EV GE DG+LWIAMDY++GID Q M DRFPAVLPVGEVL IV Sbjct 61 SAIAARLYHSHIVEVRAHGELDGRLWIAMDYIEGIDVGQLMRDRFPAVLPVGEVLEIVAP 120 Query 121 VAGA-LDYAHQRGLLHRDVNPANVVLTSQSAGDQRILLADFGIASQPSYP-------APE 172 VA A LDYAHQRGL+H DV PA++V+T+ G RILL FGIA+ P APE Sbjct 121 VADAPLDYAHQRGLVHGDVKPADIVMTNAGEGQPRILLKGFGIAAPHGAPGDATGFVAPE 180 Query 173 LSAGADVDGRADQYALALTAIHLFAGAPPVDRSHTGPLQPPKLSAFRPDLARLDGVLSRA 232 GA+ DGR+DQYALA TA+ L GA P S P PKLS RPDLARLD + +RA Sbjct 181 QLTGAEADGRSDQYALAATAMILLTGAAPGGGS---PSAAPKLSDLRPDLARLDALFARA 237 Query 233 LATAPADRFGSCREFADAMNEQAGVAIADQSSGGVDASEVTAA-----------AGEEAY 281 LAT PA RF +C E ADA+ ++ G + G D EV A+ A ++ Sbjct 238 LATEPAGRFRTCHELADALRDEVG---GSSGAAGRDDMEVGASWDLSPEAGATGASQDRE 294 Query 282 VVDYPAYGWPEAVDCKEPSARAPAPAAPTPQRRGSMLQSAAGVLARRLDNFSTATKAPAS 341 V+DYPAYGWP + P P P AP P ++LQ+ A LARRL+ FS A + P Sbjct 295 VLDYPAYGWPAVAPPQPPVHPGPMPMAPQPPA--TLLQAVAASLARRLNEFSAAGRGPRK 352 Query 342 PTRRRPRRILVGAVAVLLLAGLFAVGIVIGRKTNTTATEVARPPTSGSAVPSAPTTTVAV 401 RRIL+G+V +LL G+ AV I R+ ++ A P TS PS T+ Sbjct 353 RRL---RRILIGSVVAILLVGMLAVAIPSLREITSSPPPAAAPATSSPPAPSTSATSPQA 409 Query 402 TAPVPLDGTYRIEIQRSKQTYDYTPTPQPPDVNTWWAFRTSCTPTECLAAATMLDDNDHT 461 P PLDGTY IEIQR+KQ Y+ P+PQPP+V TWWA ++SC PT CLAAA MLD H Sbjct 410 ATPEPLDGTYSIEIQRAKQLYNGRPSPQPPNVTTWWAIQSSCIPTGCLAAAAMLDGYGHG 469 Query 462 QAKTPPVRPFLMQFGEGQWKSRPETVQFPCVGPNGSPSTQATTQLLALRPQPQGDLVGEM 521 QAK + +M+F EGQW+SRP+TV+F C+GPNG +TQ T Q+L LRPQ GDLVG + Sbjct 470 QAKQ-GIPSIIMEFSEGQWRSRPDTVRFACIGPNGEANTQTTVQVLTLRPQSTGDLVGAL 528 Query 522 VVTVHSNECGQQGAVIRIPAVASRSGDLPPAVTVPDPATIPDTPDTTSTA 571 VVTV +NECGQQ AVIRIPAVASRSGD+PP + VP+P TIP P +T+ Sbjct 529 VVTVETNECGQQSAVIRIPAVASRSGDIPPGIKVPNPVTIPKAPQAPATS 578 >gi|342858235|ref|ZP_08714890.1| PknF [Mycobacterium colombiense CECT 3035] gi|342133939|gb|EGT87119.1| PknF [Mycobacterium colombiense CECT 3035] Length=544 Score = 482 bits (1240), Expect = 8e-134, Method: Compositional matrix adjust. Identities = 284/587 (49%), Positives = 352/587 (60%), Gaps = 81/587 (13%) Query 1 MALASGVTFAGYTVVRMLGCSAMGEVYLVQHPGFPGWQALKVLSPAMAADDEFRRRFQRE 60 M+L SG +FAGY V R LG GEVYLVQ P QALKVLS ++AD +F+ RF+ E Sbjct 1 MSLPSGASFAGYIVSRGLGSGVRGEVYLVQDPQSMRRQALKVLSGELSADPDFKARFREE 60 Query 61 TEVAARLFHPHILEVHDRGEFDGQLWIAMDYVDGIDATQHMADRFPAVLPVGEVLAIVTA 120 T + L +PHI+EVH+RG+FDG+L++AM+Y++G A Q M DRFPAV P EVL +VTA Sbjct 61 TPIVVNLHYPHIVEVHERGQFDGRLYVAMEYIEGTSAAQLMTDRFPAVSPADEVLTMVTA 120 Query 121 VAGALDYAHQRGLLHRDVNPANVVLTSQSAGDQRILLADFGIASQ------------PSY 168 VAGALDY H RGL HRDV PAN++LT ++ G QRILL DFGIA Q +Y Sbjct 121 VAGALDYGHLRGLTHRDVKPANILLTDRAGGKQRILLTDFGIARQLAHAAVDATHVSVAY 180 Query 169 PAPELSAGADVDGRADQYALALTAIHLFAGAPPV---------DRSHTGPLQPPKLSAFR 219 APE +G DVDGRADQYALA TA HL G PPV R G L P+LS R Sbjct 181 AAPEQLSGGDVDGRADQYALAATAFHLLTGTPPVAHADPAAALRRHRDGKL--PRLSDQR 238 Query 220 PDLARLDGVLSRALATAPADRFGSCREFADAMNEQAGVAIADQSSGGVDASEVTAAAGEE 279 P+LA LD V ++ALA P DRF +C +FA A +E AG++ + D Sbjct 239 PELAHLDSVFAKALAERPEDRFETCHDFAQAASELAGLSTGVRPEPEAD----------- 287 Query 280 AYVVDYPAYGWPEAVDCKEPSARAPAPAAPTPQRRGSMLQSAAGVLARRLDNFSTATKAP 339 PE+ D + +A P A T T P Sbjct 288 -----------PESDDDETDTAAVPEGVAAT-------------------------TPEP 311 Query 340 ASPTRRRPRRILVGAVAVLLLAGLFAVGIVIGRKTNTTATEVARPPTSGSAVPSAPTTTV 399 P +R PR++LVGA V L+AG GI IGR T TT V +A T Sbjct 312 DVPRKRGPRKLLVGAAVVALVAGALVAGIAIGRHTGTTPKRV-----------AAAAPTT 360 Query 400 AVTAPVPLDGTYRIEIQRSKQTYDYTPTPQPPDVNTWWAFRTSCTPTECLAAATMLDDND 459 P PLDG+YRIE QR+KQTY+Y PQPPDV+TWWAFR+SCT C AAA LDDND Sbjct 361 PAPRPAPLDGSYRIEAQRTKQTYNYVADPQPPDVSTWWAFRSSCTQKGCSAAAMQLDDND 420 Query 460 HTQAKTPPVRPFLMQFGEGQWKSRPETVQFPCVGPNGSPSTQATTQLLALRPQPQGDLVG 519 H QA +P MQF +G+W+S P + FPCVGP+GS S Q+TT +LALRPQP G+ VG Sbjct 421 HVQAMSPGGGSLFMQFADGEWQSAPVDLDFPCVGPDGSQSAQSTTMVLALRPQPNGEFVG 480 Query 520 EMVVTVHSNECGQQGAVIRIPAVASRSGDLPPAVTVPDPATIPDTPD 566 E VVTV ++ECGQ+ AVIR+P VA R+G++PPAV VP+P + P +P+ Sbjct 481 EEVVTVRTDECGQRSAVIRVPTVARRTGEVPPAVAVPEPGSGPQSPE 527 >gi|342860791|ref|ZP_08717441.1| PknF protein [Mycobacterium colombiense CECT 3035] gi|342131815|gb|EGT85072.1| PknF protein [Mycobacterium colombiense CECT 3035] Length=675 Score = 379 bits (972), Expect = 9e-103, Method: Compositional matrix adjust. Identities = 242/596 (41%), Positives = 314/596 (53%), Gaps = 86/596 (14%) Query 1 MALASGVTFAGYTVVRMLGCSAMGEVYLVQHPGFPGWQALKVLSPAMAADDEFRRRFQRE 60 +A+ +G +FAGYT++R LG M EVYL HP P +KVL+ A+ AD EFR RF RE Sbjct 56 LAVGNGASFAGYTILRQLGAGGMAEVYLALHPRLPRRDVIKVLAEAVTADPEFRERFNRE 115 Query 61 TEVAARLFHPHILEVHDRGEFDGQLWIAMDYVDGIDATQHMADRFPAVLPVGEVLAIVTA 120 ++AA L+HPHI+ VHDRGEF+G LWI+MDYV+G DA++ + + + +P+ EV AIV A Sbjct 116 ADLAATLWHPHIVGVHDRGEFNGHLWISMDYVEGTDASRLVKENYAGGMPIDEVCAIVQA 175 Query 121 VAGALDYAHQRGLLHRDVNPANVVLTSQSAGDQRILLADFGIASQ--------------- 165 VAGALDYAH RGLLHRDV PAN++LT G++RILLADFG+A Sbjct 176 VAGALDYAHDRGLLHRDVKPANILLTHPDEGERRILLADFGVARHLGDISGITETNVAVG 235 Query 166 -PSYPAPELSAGADVDGRADQYALALTAIHLFAGAPPVDRSHTGPL---------QPPKL 215 +Y APE G+ +DGRADQYALA TA HL GAPP H+ P+ PP+L Sbjct 236 TVAYAAPEQLTGSPIDGRADQYALAATAFHLLTGAPPF--QHSNPIAVISQHLHEDPPRL 293 Query 216 SAFRPDLARLDGVLSRALATAPADRFGSCREFADAMNEQAGVAIADQSSGGVDASEVTAA 275 S FRPDLA LD V RALA P DRF CR FA A+ E S+GGV S+V Sbjct 294 SDFRPDLAELDDVFFRALAKQPEDRFERCRAFAAAVVE---------SAGGV--SDVG-- 340 Query 276 AGEEAYVVDYPAYGWPEAVDCKEPSARAPAPAAPTPQRRGSMLQSAAGVLARRLDNFSTA 335 P AR P PAA T RR + AGV+A FS Sbjct 341 -----------------------PGAR-PRPAASTSHRR----RGPAGVVAGLSHRFSAK 372 Query 336 TKAPASPTRRRPRRILVGAVAVLLLAGLFAVGIVIGRKTNTTATEVARPPTSGSAVPSAP 395 T R V +L+A ++ + + A P + A Sbjct 373 T------------RWATALVCAVLIAVAATWSLLYSFQPDAPP---ASPALASRPSAPAA 417 Query 396 TTTVAVTAPVPLDGTYRIEIQRSKQTYDYTPTPQPPDVNTWWAFRTSCTPTECLAAATML 455 + PV L+G Y+++ ++K+T + WWAFR+ CT C A T L Sbjct 418 SAAPTAGGPV-LNGVYKLDYDQTKRTTNGISIRHDGAATGWWAFRSVCTANGCAATGTQL 476 Query 456 DDNDHTQAKTPPV-RPFLMQFGEGQWKSRPETVQFPCVGPNGS-PSTQATTQLLALRPQP 513 DD H A T + ++F G W+ P + C PNG +TQ T +L PQ Sbjct 477 DDATHQVANTTDGGQADTLRFVGGYWQGAPAQQRVGCTQPNGQVRATQQETIAWSLAPQA 536 Query 514 QGDLVGEMVVTVHSNECGQQGAVIRIPAVASRSGDLPPAVTVPDPATIPDTPDTTS 569 G L G + TV SNECG QGAV+R+P VA+R+GD+P VT+ DP + + T S Sbjct 537 DGTLRGTLTETVLSNECGAQGAVVRVPVVATRTGDVPATVTLGDPTQVINASTTAS 592 >gi|296164508|ref|ZP_06847079.1| non-specific serine/threonine protein kinase [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295900108|gb|EFG79543.1| non-specific serine/threonine protein kinase [Mycobacterium parascrofulaceum ATCC BAA-614] Length=665 Score = 287 bits (734), Expect = 4e-75, Method: Compositional matrix adjust. Identities = 152/287 (53%), Positives = 188/287 (66%), Gaps = 28/287 (9%) Query 2 ALASGVTFAGYTVVRMLGCSAMGEVYLVQHPGFPGWQALKVLSPAMAADDEFRRRFQRET 61 ++ SG FAGYT++R LG M EVYL HP P +KVL+ A+ AD EFR RF RE Sbjct 66 SVTSGAPFAGYTILRQLGAGGMAEVYLALHPRLPRRDVIKVLAEAVTADPEFRERFNREA 125 Query 62 EVAARLFHPHILEVHDRGEFDGQLWIAMDYVDGIDATQHMADRFPAVLPVGEVLAIVTAV 121 ++AA L+HPH++ VHDRGEFDG LWI+MDYV+G DA++ + +R+ +PV EV AIV AV Sbjct 126 DLAATLWHPHVVGVHDRGEFDGHLWISMDYVEGTDASRLVKERYHDGMPVDEVCAIVEAV 185 Query 122 AGALDYAHQRGLLHRDVNPANVVLTSQSAGDQRILLADFGIASQ---------------- 165 AGALDYAH RGLLHRDV PAN++LT G +RILLADFG+A Sbjct 186 AGALDYAHDRGLLHRDVKPANILLTHPEGGQRRILLADFGVARHLGDISGITETNVAVGT 245 Query 166 PSYPAPELSAGADVDGRADQYALALTAIHLFAGAPPVDRSHTGPL---------QPPKLS 216 +Y APE G+++DGRADQYALA TA HL GAPP H+ P+ +PP+LS Sbjct 246 VAYAAPEQLTGSNIDGRADQYALAATAFHLLTGAPPF--RHSNPIAVIGQHLHEEPPRLS 303 Query 217 AFRPDLARLDGVLSRALATAPADRFGSCREFADAMNEQAG-VAIADQ 262 RP+LARLD V RALA P DRF CR FA A+ ++ G VA A Q Sbjct 304 DHRPELARLDEVFRRALAKNPDDRFERCRGFAAAVADRLGDVAEAGQ 350 Score = 108 bits (269), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 84/263 (32%), Positives = 120/263 (46%), Gaps = 22/263 (8%) Query 308 APTPQRRGSMLQSAAGVLARRLDNFSTATKAPASPTRRRPR-------RILVGAVAVLLL 360 A P R + A +A RL + + A + T PR R V V +L+ Sbjct 321 AKNPDDRFERCRGFAAAVADRLGDVAEAGQRARPGTVAAPRHRFSARARWAVALVCAMLV 380 Query 361 AGLFAVGIVIGRKTNTTATEVARPPTSGSAVPSAPTTTVAVTAPVP-LDGTYRIEIQRSK 419 A V + + E PP S A+ S P+ T+ P L+GTY+++ +SK Sbjct 381 A-------VAATCSALYSVEPDTPPAS-PALASKPSVPAPTTSGGPALNGTYQLDYDQSK 432 Query 420 QTYDYTPTPQPPDVNTWWAFRTSCTPTECLAAATMLDDNDHTQAKTPPVRPFLMQFGEGQ 479 +T + WWAFR+ CT C A LDD H A R + F G Sbjct 433 RTTNGVAIRHSGPATGWWAFRSVCTTNGCAATGARLDDATHQAAGG---RTDTLHFVGGY 489 Query 480 WKSRPETVQFPCVGPN---GSPSTQATTQLLALRPQPQGDLVGEMVVTVHSNECGQQGAV 536 W+ P+ + C P+ G+ +TQ T +L PQ G L G + TV S+ECG +GAV Sbjct 490 WQGAPQQDRVDCARPDAPAGAAATQQETVAWSLAPQADGTLRGTVTETVLSDECGARGAV 549 Query 537 IRIPAVASRSGDLPPAVTVPDPA 559 +R+P V +R GD+P V + DPA Sbjct 550 VRVPVVGTRVGDVPAGVNLADPA 572 >gi|41407430|ref|NP_960266.1| PknF [Mycobacterium avium subsp. paratuberculosis K-10] gi|41395782|gb|AAS03649.1| PknF [Mycobacterium avium subsp. paratuberculosis K-10] Length=620 Score = 285 bits (729), Expect = 2e-74, Method: Compositional matrix adjust. Identities = 148/285 (52%), Positives = 185/285 (65%), Gaps = 27/285 (9%) Query 1 MALASGVTFAGYTVVRMLGCSAMGEVYLVQHPGFPGWQALKVLSPAMAADDEFRRRFQRE 60 M + +G +FAGYT++R LG M EVYL HP P +KVL+ A+ D EFR RF RE Sbjct 1 MTIGNGASFAGYTILRQLGAGGMAEVYLALHPRLPRRDVIKVLAEAVTVDPEFRERFNRE 60 Query 61 TEVAARLFHPHILEVHDRGEFDGQLWIAMDYVDGIDATQHMADRFPAVLPVGEVLAIVTA 120 ++AA L+HPHI+ VHDRGEF+G LWI+MDYV+G DA++ + + +P +P+ EV AIV A Sbjct 61 ADLAATLWHPHIVGVHDRGEFNGHLWISMDYVEGTDASRLVKESYPDGMPLDEVSAIVQA 120 Query 121 VAGALDYAHQRGLLHRDVNPANVVLTSQSAGDQRILLADFGIASQ--------------- 165 VAGALDYAH RGLLHRDV PAN++LT AG++RILLADFG+A Sbjct 121 VAGALDYAHARGLLHRDVKPANILLTHPEAGERRILLADFGVARHLGDISGITETNVAVG 180 Query 166 -PSYPAPELSAGADVDGRADQYALALTAIHLFAGAPPVDRSHTGPL---------QPPKL 215 +Y APE G+ +DGRADQYALA TA HL GAPP H+ P+ PP+L Sbjct 181 TVAYAAPEQLTGSPIDGRADQYALAATAFHLLTGAPPF--QHSNPIAVIGQHLHEDPPRL 238 Query 216 SAFRPDLARLDGVLSRALATAPADRFGSCREFADAMNEQAGVAIA 260 S FRP+LA LD V +ALA AP DRF CR FA A+ + A A Sbjct 239 SDFRPELAGLDEVFCQALAKAPEDRFDRCRAFAAAVRRECDGAAA 283 Score = 122 bits (306), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 71/179 (40%), Positives = 97/179 (55%), Gaps = 12/179 (6%) Query 407 LDGTYRIEIQRSKQTYDYTPTPQPPDVNTWWAFRTSCTPTECLAAATMLDDNDHTQAKTP 466 L+GTY+++ ++K+T + WWAFR++CT + C A T LDD H A P Sbjct 373 LNGTYKLDYDQTKRTTNGIGIRHDGAGTNWWAFRSACTSSGCAATGTRLDDATHQTAGGP 432 Query 467 PV-RPFLMQFGEGQWKSRPETVQFPCVGPNG-SPSTQATTQLLALRPQPQGDLVGEMVVT 524 + ++F G W+ PE + C P G + +TQ T +L PQ G L G T Sbjct 433 DGGQTDTLRFVGGYWQGAPEQQRVGCTRPGGPAGATQQETIAWSLAPQSDGTLRGTETET 492 Query 525 VHSNECGQQGAVIRIPAVASRSGDLPPAVTVPDPATIPDTPDTTSTATLTPPTTTAPGP 583 V SNECG QGAV+R+P VA+R GD+PP VTV DPA++ + PT TAP P Sbjct 493 VLSNECGAQGAVVRVPVVATRVGDVPPGVTVADPASVIN----------ASPTATAPAP 541 >gi|336457782|gb|EGO36776.1| serine/threonine protein kinase [Mycobacterium avium subsp. paratuberculosis S397] Length=686 Score = 284 bits (727), Expect = 3e-74, Method: Compositional matrix adjust. Identities = 147/285 (52%), Positives = 186/285 (66%), Gaps = 27/285 (9%) Query 1 MALASGVTFAGYTVVRMLGCSAMGEVYLVQHPGFPGWQALKVLSPAMAADDEFRRRFQRE 60 + + +G +FAGYT++R LG M EVYL HP P +KVL+ A+ D EFR RF RE Sbjct 72 LTIGNGASFAGYTILRQLGAGGMAEVYLALHPRLPRRDVIKVLAEAVTVDPEFRERFNRE 131 Query 61 TEVAARLFHPHILEVHDRGEFDGQLWIAMDYVDGIDATQHMADRFPAVLPVGEVLAIVTA 120 ++AA L+HPHI+ VHDRGEF+G LWI+MDYV+G DA++ + + +P +P+ EV AIV A Sbjct 132 ADLAATLWHPHIVGVHDRGEFNGHLWISMDYVEGTDASRLVKESYPDGMPLDEVSAIVQA 191 Query 121 VAGALDYAHQRGLLHRDVNPANVVLTSQSAGDQRILLADFGIASQ--------------- 165 VAGALDYAH RGLLHRDV PAN++LT AG++RILLADFG+A Sbjct 192 VAGALDYAHARGLLHRDVKPANILLTHPEAGERRILLADFGVARHLGDISGITETNVAVG 251 Query 166 -PSYPAPELSAGADVDGRADQYALALTAIHLFAGAPPVDRSHTGPL---------QPPKL 215 +Y APE G+ +DGRADQYALA TA HL GAPP H+ P+ PP+L Sbjct 252 TVAYAAPEQLTGSPIDGRADQYALAATAFHLLTGAPPF--QHSNPIAVIGQHLHEDPPRL 309 Query 216 SAFRPDLARLDGVLSRALATAPADRFGSCREFADAMNEQAGVAIA 260 S FRP+LA LD V +ALA AP DRF CR FA A++ + A A Sbjct 310 SDFRPELAGLDEVFCQALAKAPEDRFDRCRAFAAAVSRECDGAAA 354 Score = 109 bits (272), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 69/179 (39%), Positives = 93/179 (52%), Gaps = 17/179 (9%) Query 407 LDGTYRIEIQRSKQTYDYTPTPQPPDVNTWWAFRTSCTPTECLAAATMLDDNDHTQAKTP 466 L+GTY+++ ++K+T + WWAFR++CT + C A T LDD H A P Sbjct 444 LNGTYKLDYDQTKRTTNGIGIRHDGAGTNWWAFRSACTSSGCAATGTRLDDATHQTAGGP 503 Query 467 P-VRPFLMQFGEGQWKSRPETVQFPCVGPNG-SPSTQATTQLLALRPQPQGDLVGEMVVT 524 + ++F G W+ PE + C P G + +TQ T +L PQ G L G T Sbjct 504 DGGQTDTLRFVGGYWQGAPEQQRVGCTRPGGPAGATQQETIAWSLAPQSDGTLRGTETET 563 Query 525 VHSNECGQQGAVIRIPAVASRSGDLPPAVTVPDPATIPDTPDTTSTATLTPPTTTAPGP 583 V SNECG QGAV VA+R GD+PP VTV DPA++ + PT TAP P Sbjct 564 VLSNECGAQGAV-----VATRVGDVPPGVTVADPASVIN----------ASPTATAPAP 607 >gi|254775595|ref|ZP_05217111.1| PknF protein [Mycobacterium avium subsp. avium ATCC 25291] Length=674 Score = 284 bits (726), Expect = 3e-74, Method: Compositional matrix adjust. Identities = 147/285 (52%), Positives = 186/285 (66%), Gaps = 27/285 (9%) Query 1 MALASGVTFAGYTVVRMLGCSAMGEVYLVQHPGFPGWQALKVLSPAMAADDEFRRRFQRE 60 + + +G +FAGYT++R LG M EVYL HP P +KVL+ A+ D EFR RF RE Sbjct 55 LTIGNGASFAGYTILRQLGAGGMAEVYLALHPRLPRRDVIKVLAEAVTVDPEFRERFNRE 114 Query 61 TEVAARLFHPHILEVHDRGEFDGQLWIAMDYVDGIDATQHMADRFPAVLPVGEVLAIVTA 120 ++AA L+HPHI+ VHDRGEF+G LWI+MDYV+G DA++ + + +P +P+ EV AIV A Sbjct 115 ADLAATLWHPHIVGVHDRGEFNGHLWISMDYVEGTDASRLVKESYPDGMPLDEVSAIVQA 174 Query 121 VAGALDYAHQRGLLHRDVNPANVVLTSQSAGDQRILLADFGIASQ--------------- 165 VAGALDYAH RGLLHRDV PAN++LT AG++RILLADFG+A Sbjct 175 VAGALDYAHARGLLHRDVKPANILLTHPEAGERRILLADFGVARHLGDISGITETNVAVG 234 Query 166 -PSYPAPELSAGADVDGRADQYALALTAIHLFAGAPPVDRSHTGPL---------QPPKL 215 +Y APE G+ +DGRADQYALA TA HL GAPP H+ P+ PP+L Sbjct 235 TVAYAAPEQLTGSPIDGRADQYALAATAFHLLTGAPPF--QHSNPIAVIGQHLHEDPPRL 292 Query 216 SAFRPDLARLDGVLSRALATAPADRFGSCREFADAMNEQAGVAIA 260 S FRP+LA LD V +ALA AP DRF CR FA A++ + A A Sbjct 293 SDFRPELAALDEVFCQALAKAPEDRFDRCRAFAAAVSRECDGAAA 337 Score = 120 bits (300), Expect = 8e-25, Method: Compositional matrix adjust. Identities = 65/157 (42%), Positives = 90/157 (58%), Gaps = 2/157 (1%) Query 407 LDGTYRIEIQRSKQTYDYTPTPQPPDVNTWWAFRTSCTPTECLAAATMLDDNDHTQAKTP 466 L+GTY+++ ++K+T + WWAFR++CT + C A T LDD H A P Sbjct 427 LNGTYKLDYDQTKRTTNGIGIRHDGAGTNWWAFRSACTSSGCAATGTRLDDATHQTAGGP 486 Query 467 PV-RPFLMQFGEGQWKSRPETVQFPCVGPNG-SPSTQATTQLLALRPQPQGDLVGEMVVT 524 + ++F G W+ PE + C P G + +TQ T +L PQ G L G T Sbjct 487 DGGQTDTLRFVGGYWQGAPEQQRVGCTRPGGPAGATQQETIAWSLAPQSDGTLRGTETET 546 Query 525 VHSNECGQQGAVIRIPAVASRSGDLPPAVTVPDPATI 561 V SNECG QGAV+R+P VA+R GD+PP VTV DPA++ Sbjct 547 VLSNECGAQGAVVRVPVVATRVGDVPPGVTVADPASV 583 >gi|333989985|ref|YP_004522599.1| anchored-membrane serine/threonine-protein kinase PknF_3 [Mycobacterium sp. JDM601] gi|333485953|gb|AEF35345.1| anchored-membrane serine/threonine-protein kinase PknF_3 [Mycobacterium sp. JDM601] Length=423 Score = 283 bits (725), Expect = 4e-74, Method: Compositional matrix adjust. Identities = 154/278 (56%), Positives = 178/278 (65%), Gaps = 27/278 (9%) Query 1 MALASGVTFAGYTVVRMLGCSAMGEVYLVQHPGFPGWQALKVLSPAMAADDEFRRRFQRE 60 M LA G FAGY + R+LG AMGEVYL +HP P ALKVL + D EFR+RFQ E Sbjct 1 MPLALGAEFAGYRIERLLGSGAMGEVYLARHPRLPRRDALKVLPAGLTTDAEFRQRFQLE 60 Query 61 TEVAARLFHPHILEVHDRGEFDGQLWIAMDYVDGIDATQHMADRFPAVLPVGEVLAIVTA 120 ++AA LFHP+I+ VHDRGEFDGQLWIAMDYV G DA + +ADR+P +P E L IV A Sbjct 61 ADLAATLFHPNIVGVHDRGEFDGQLWIAMDYVAGTDAARFVADRYPNGMPEDEALPIVGA 120 Query 121 VAGALDYAHQRGLLHRDVNPANVVLTSQSAGDQRILLADFGIASQ--------------- 165 +A ALD+AHQRGLLHRDV PAN+++ G QRILLADFGI Q Sbjct 121 IAEALDHAHQRGLLHRDVKPANILIADPEGGSQRILLADFGIVRQLGTVGGLTATNFTVG 180 Query 166 -PSYPAPELSAGADVDGRADQYALALTAIHLFAGAPP---------VDRSHTGPLQPPKL 215 SY APE G D+DGRADQYALA TA HL GAPP + R T PP+L Sbjct 181 TVSYAAPEQLRGDDLDGRADQYALAATAFHLLTGAPPFGDGNPVTVISRHLTA--APPRL 238 Query 216 SAFRPDLARLDGVLSRALATAPADRFGSCREFADAMNE 253 S RP+LA LD VL+ LA PA RFG CR FA A+ E Sbjct 239 SERRPELAHLDAVLATGLAKDPAGRFGGCRAFARALAE 276 >gi|254820994|ref|ZP_05225995.1| PknF protein [Mycobacterium intracellulare ATCC 13950] Length=341 Score = 283 bits (724), Expect = 6e-74, Method: Compositional matrix adjust. Identities = 148/275 (54%), Positives = 180/275 (66%), Gaps = 27/275 (9%) Query 2 ALASGVTFAGYTVVRMLGCSAMGEVYLVQHPGFPGWQALKVLSPAMAADDEFRRRFQRET 61 A+ +G +FAGYT++R LG M EVYL HP P +KVL+ A+ AD EFR RF RE Sbjct 69 AVGNGASFAGYTILRQLGAGGMAEVYLALHPRLPRRDVIKVLAEAVTADPEFRERFNREA 128 Query 62 EVAARLFHPHILEVHDRGEFDGQLWIAMDYVDGIDATQHMADRFPAVLPVGEVLAIVTAV 121 ++AA L+HPHI+ VHDRG F+G LWI+MDYV+G DA++ + P +P+ EV AIV AV Sbjct 129 DLAATLWHPHIVGVHDRGAFNGHLWISMDYVEGTDASRLVKQSHPEGMPIHEVCAIVQAV 188 Query 122 AGALDYAHQRGLLHRDVNPANVVLTSQSAGDQRILLADFGIASQ---------------- 165 AGALDYAH RGLLHRDV PAN++LT G++RILLADFG+A Sbjct 189 AGALDYAHDRGLLHRDVKPANILLTHPEDGERRILLADFGVARHLGDVSGITETNVAVGT 248 Query 166 PSYPAPELSAGADVDGRADQYALALTAIHLFAGAPPVDRSHTGPL---------QPPKLS 216 +Y APE AGA +DGRADQYALA TA HL GAPP H+ P+ PP+LS Sbjct 249 VAYAAPEQLAGAPIDGRADQYALAATAFHLLTGAPPF--QHSNPIAVISRHLHETPPRLS 306 Query 217 AFRPDLARLDGVLSRALATAPADRFGSCREFADAM 251 FRP+LA LD V S ALA P DRF CREFA A+ Sbjct 307 DFRPELAELDDVFSTALAKRPEDRFARCREFATAV 341 >gi|126437262|ref|YP_001072953.1| protein kinase [Mycobacterium sp. JLS] gi|126237062|gb|ABO00463.1| protein kinase [Mycobacterium sp. JLS] Length=587 Score = 280 bits (717), Expect = 4e-73, Method: Compositional matrix adjust. Identities = 147/279 (53%), Positives = 181/279 (65%), Gaps = 23/279 (8%) Query 1 MALASGVTFAGYTVVRMLGCSAMGEVYLVQHPGFPGWQALKVLSPAMAADDEFRRRFQRE 60 M L +G FAGYT+VR++G MGEVYL QHP P ALKVL + +ADDE+R RF RE Sbjct 1 MPLETGQVFAGYTIVRLVGTGGMGEVYLAQHPRLPRQDALKVLPASFSADDEYRHRFSRE 60 Query 61 TEVAARLFHPHILEVHDRGEFDGQLWIAMDYVDGIDATQHMADRFPAVLPVGEVLAIVTA 120 ++AA L+HPHI+ VHDRGE+DG+LWI+MD+VDG DA + + DR+P LP +V+ IVTA Sbjct 61 ADLAAALWHPHIVGVHDRGEYDGRLWISMDFVDGHDAARLLVDRYPNGLPAADVIEIVTA 120 Query 121 VAGALDYAHQRGLLHRDVNPANVVLTSQSAGDQRILLADFGIASQP-------------- 166 VA ALDYAHQR LLHRDV PAN+++T +RILLADFGIA Sbjct 121 VADALDYAHQRQLLHRDVKPANILITGPDRARRRILLADFGIARHTEDNTGLTSSNIAVG 180 Query 167 --SYPAPELSAGADVDGRADQYALALTAIHLFAGAPP-------VDRSHTGPLQPPKLSA 217 SY APE G +DGRADQY+LA TA LF G+PP V SH PP+L Sbjct 181 SMSYSAPEQLMGHPIDGRADQYSLAATAYRLFTGSPPFPHSNPAVIISHHLNTPPPRLGD 240 Query 218 FRPDLARLDGVLSRALATAPADRFGSCREFADAMNEQAG 256 RP+L D ++RALA PA RFGSC +FA A+ + G Sbjct 241 TRPELRAFDAAMARALAKDPAARFGSCHDFAVALAQATG 279 >gi|118462529|ref|YP_882329.1| PknF protein [Mycobacterium avium 104] gi|118163816|gb|ABK64713.1| PknF protein [Mycobacterium avium 104] Length=691 Score = 280 bits (716), Expect = 6e-73, Method: Compositional matrix adjust. Identities = 145/285 (51%), Positives = 184/285 (65%), Gaps = 27/285 (9%) Query 1 MALASGVTFAGYTVVRMLGCSAMGEVYLVQHPGFPGWQALKVLSPAMAADDEFRRRFQRE 60 + + +G +FAGYT++R LG M EVYL HP P +KVL+ A+ D EFR RF RE Sbjct 72 LTIGNGASFAGYTILRQLGAGGMAEVYLALHPRLPRRDVIKVLAEAVTVDPEFRERFNRE 131 Query 61 TEVAARLFHPHILEVHDRGEFDGQLWIAMDYVDGIDATQHMADRFPAVLPVGEVLAIVTA 120 ++AA L+HPHI+ VHDRGEF+G LWI+MDYV+G DA++ + + + +P+ EV AIV A Sbjct 132 ADLAATLWHPHIVGVHDRGEFNGHLWISMDYVEGTDASRLVKESYADGMPLDEVSAIVQA 191 Query 121 VAGALDYAHQRGLLHRDVNPANVVLTSQSAGDQRILLADFGIASQ--------------- 165 VAGALDYAH RGLLHRDV PAN++LT AG++RILLADFG+A Sbjct 192 VAGALDYAHARGLLHRDVKPANILLTHPEAGERRILLADFGVARHLGDISGITETNVAVG 251 Query 166 -PSYPAPELSAGADVDGRADQYALALTAIHLFAGAPPVDRSHTGPL---------QPPKL 215 +Y APE G+ +DGRADQYALA TA HL GAPP H+ P+ PP+L Sbjct 252 TVAYAAPEQLTGSPIDGRADQYALAATAFHLLTGAPPF--QHSNPIAVIGQHLHEDPPRL 309 Query 216 SAFRPDLARLDGVLSRALATAPADRFGSCREFADAMNEQAGVAIA 260 S FRP+LA LD V +ALA P DRF CR FA A++ + A A Sbjct 310 SDFRPELAALDEVFCQALAKVPEDRFDRCRAFAAAVSRECDGAAA 354 Score = 121 bits (304), Expect = 3e-25, Method: Compositional matrix adjust. Identities = 71/179 (40%), Positives = 97/179 (55%), Gaps = 12/179 (6%) Query 407 LDGTYRIEIQRSKQTYDYTPTPQPPDVNTWWAFRTSCTPTECLAAATMLDDNDHTQAKTP 466 L+GTY+++ ++K+T + WWAFR++CT + C A T LDD H A P Sbjct 444 LNGTYKLDYDQTKRTTNGIGIRHDGAGTNWWAFRSACTSSGCAATGTRLDDATHQAAGGP 503 Query 467 PV-RPFLMQFGEGQWKSRPETVQFPCVGPNG-SPSTQATTQLLALRPQPQGDLVGEMVVT 524 + ++F G W+ PE + C P G + +TQ T +L PQ G L G T Sbjct 504 DGDQTDTLRFVGGYWQGAPEQQRVGCTRPGGPAGATQQETIARSLAPQSDGTLRGTETET 563 Query 525 VHSNECGQQGAVIRIPAVASRSGDLPPAVTVPDPATIPDTPDTTSTATLTPPTTTAPGP 583 V SNECG QGAV+R+P VA+R GD+PP VTV DPA++ + PT TAP P Sbjct 564 VLSNECGAQGAVVRVPVVATRVGDVPPGVTVADPASVIN----------ASPTATAPAP 612 >gi|240172042|ref|ZP_04750701.1| anchored-membrane serine/threonine-protein kinase [Mycobacterium kansasii ATCC 12478] Length=639 Score = 278 bits (712), Expect = 2e-72, Method: Compositional matrix adjust. Identities = 200/591 (34%), Positives = 282/591 (48%), Gaps = 111/591 (18%) Query 1 MALASGVTFAGYTVVRMLGCSAMGEVYLVQHPGFPGWQALKVLSPAMAADDEFRRRFQRE 60 M++ G FAGYT++R LG MG VYL +HP P +ALK+L + D E+R RF+RE Sbjct 1 MSVEVGQVFAGYTILRELGTGGMGRVYLARHPRLPRDEALKILPEELTGDPEYRARFERE 60 Query 61 TEVAARLFHPHILEVHDRGEFDGQLWIAMDYVDGIDATQHMADRFPAVLPVGEVLAIVTA 120 ++AA L HPHI+ +HDRGEF +LWI+M+YVDG D + + ++FP +P+ I+TA Sbjct 61 ADLAAGLNHPHIVRIHDRGEFQDRLWISMEYVDGTDVARLLLEQFPGGMPLDAAAPIITA 120 Query 121 VAGALDYAHQRGLLHRDVNPANVVLTSQSAGD-QRILLADFGIASQ-------------- 165 V ALDYAH RGL HRDV PAN++LT+ G +R+ LADFG+A + Sbjct 121 VGSALDYAHHRGLFHRDVKPANILLTAPDGGQARRVFLADFGLARRIDDATGLTATGATV 180 Query 166 --PSYPAPELSAGADVDGRADQYALALTAIHLFAGAPPVDRSHTGPLQ-------PPKLS 216 +Y APE G VDGRADQYALA TA +L G PP S+ + PP + Sbjct 181 GTVAYLAPEQLTGDPVDGRADQYALACTAFNLLTGVPPYGDSNPTVVISQHINAPPPPIG 240 Query 217 AFRPDLARLDGVLSRALATAPADRFGSCREFADAMNEQA--GVAIADQSSGGVDASEVTA 274 A+R +LA L+ V ++A+A PADRFGSC EFA +++Q G A A + D ++ Sbjct 241 AYRSELAALNSVFAKAMAKNPADRFGSCAEFAAQLSQQLNPGFAYAGEIPLRADTADT-- 298 Query 275 AAGEEAYVVDYPAYGWPEAVDCKEPSARAPAPAAP-TPQRRGSMLQSAAGVLARRLDNFS 333 +P+ PA P TP R + Q Sbjct 299 -----------------------QPAIDRTVPALPRTPAGRKRLGQ-------------- 321 Query 334 TATKAPASPTRRRPRRILVGAVAVLLL--AGLFAVGIVIGRKTNTTATEVARPPTSGSAV 391 RP ++ V++LLL G+FAV T+ +P T+ Sbjct 322 ------------RPGLLIGALVSILLLIAGGVFAV---------VKLTQSHKPGTTARNA 360 Query 392 PSAPTTTVAVTAPVPLDGTYRIEIQRSKQTYDYTPTPQPPDVNTWWAFRTSCTPTECLAA 451 PS+ TTTVA T P G YR + + T+ P P P +A R+ C C A Sbjct 361 PSSTTTTVANTG--PFTGVYRADFGKGA-TFADAPIPGVPPSTDTYAVRSVCGTAGCAAT 417 Query 452 ATMLDDNDHTQAKTPPVRPFLMQFGEGQWKSRPETVQFPCVGPNGSPSTQATTQLLALRP 511 A+ H +T + G+W V G+P+ ++ L+P Sbjct 418 AS------HLSGETTFAPAMVFDEVGGRWLG----VAIGLDKCQGAPA--EIWEVFTLQP 465 Query 512 QPQGDLVGEMVVTVHSNECGQQGAVIRIPAVASRSGDLPPAVTVPDPATIP 562 P G GE T +N G+ +R+GD+ ++PDPA +P Sbjct 466 GPGGAFTGEFTATTSNNCVGKHTVTF------TRTGDV-DLNSLPDPAALP 509 >gi|118468993|ref|YP_889750.1| serine/threonine protein kinase [Mycobacterium smegmatis str. MC2 155] gi|118170280|gb|ABK71176.1| serine/threonine-protein kinase PknE [Mycobacterium smegmatis str. MC2 155] Length=618 Score = 276 bits (707), Expect = 6e-72, Method: Compositional matrix adjust. Identities = 142/278 (52%), Positives = 184/278 (67%), Gaps = 27/278 (9%) Query 1 MALASGVTFAGYTVVRMLGCSAMGEVYLVQHPGFPGWQALKVLSPAMAADDEFRRRFQRE 60 M LASG FAG+T+VR++G MGEVYL +HP P ALKVL +++ADDEFR+RF RE Sbjct 1 MPLASGQVFAGFTIVRLVGTGGMGEVYLAKHPRLPREDALKVLPISVSADDEFRQRFIRE 60 Query 61 TEVAARLFHPHILEVHDRGEFDGQLWIAMDYVDGIDATQHMADRFPAVLPVGEVLAIVTA 120 ++AA L+HPHI+ VHDRGEF+G+LWI+MDYVDG DA + + D++P +P +V+ IVTA Sbjct 61 ADMAATLWHPHIVGVHDRGEFEGRLWISMDYVDGHDAARLLHDKYPKGMPADDVVEIVTA 120 Query 121 VAGALDYAHQRGLLHRDVNPANVVLTSQSAGDQRILLADFGIASQP-------------- 166 V ALDYAHQR LLHRDV PAN+++T + +RI+L DFGIA + Sbjct 121 VGDALDYAHQRQLLHRDVKPANILVTEKHGTKRRIMLTDFGIARRTDDVNGLTSTNITVG 180 Query 167 --SYPAPELSAGADVDGRADQYALALTAIHLFAGAPPVDRSHTGPLQ---------PPKL 215 SY +PE G +DGRADQY+LA TA L GAPP SH+ P PPKL Sbjct 181 SMSYTSPEQLMGQPLDGRADQYSLAATAYRLLTGAPPF--SHSNPAVVISHHLNSPPPKL 238 Query 216 SAFRPDLARLDGVLSRALATAPADRFGSCREFADAMNE 253 +P LA+LD V+++ALA DRF +C +FA A+ E Sbjct 239 GDTKPALAKLDSVMAKALAKDAKDRFDTCHDFAVALAE 276 >gi|240172658|ref|ZP_04751317.1| anchored-membrane serine/threonine-protein kinase pknF [Mycobacterium kansasii ATCC 12478] Length=487 Score = 276 bits (706), Expect = 8e-72, Method: Compositional matrix adjust. Identities = 150/297 (51%), Positives = 182/297 (62%), Gaps = 31/297 (10%) Query 1 MALASGVTFAGYTVVRMLGCSAMGEVYLVQHPGFPGWQALKVLSPAMAADDEFRRRFQRE 60 M LA G TFAGYT+VR LG MGEVYL +HP P ALKVL P ++AD E+R RF RE Sbjct 8 MPLAEGSTFAGYTIVRQLGSGGMGEVYLARHPRLPRQDALKVLRPEVSADTEYRERFNRE 67 Query 61 TEVAARLFHPHILEVHDRGEFDGQLWIAMDYVDGIDATQHMADRFPAVLPVGEVLAIVTA 120 + AA L+HPHI+ VHDRGE DGQLWI MDYVDG+DA + + +R+P +P EV AI+TA Sbjct 68 ADAAASLWHPHIVAVHDRGETDGQLWIDMDYVDGVDAVRLLRERYPNGMPGPEVTAIITA 127 Query 121 VAGALDYAHQRGLLHRDVNPANVVLTSQSAGDQRILLADFGIA----------------S 164 VA ALDYAH+ LLHRDV PAN+++ + D+RI+LADFGIA Sbjct 128 VAEALDYAHEHKLLHRDVKPANILIAKPDSPDRRIMLADFGIAGWVGEASGLTATNMTVG 187 Query 165 QPSYPAPELSAGADVDGRADQYALALTAIHLFAGAPPVDRSHTGPL-------QPPKLSA 217 SY APE G D+DGRADQYALA TA HL G PP S+ + PP + Sbjct 188 TVSYAAPEQLMGQDLDGRADQYALAATAFHLLTGTPPFQHSNPAVVISQHLSASPPPIGD 247 Query 218 FRPDLARLDGVLSRALATAPADRFGSCREFADAMNEQAGVAIADQSSGGVDASEVTA 274 P LA LD V ++ALA P DR+ C +FA A+ + G GG DA E A Sbjct 248 RLPALADLDPVFAKALAKDPKDRYQRCIDFARALGHRLG--------GGGDADETIA 296 >gi|118473542|ref|YP_887980.1| serine/threonine protein kinase [Mycobacterium smegmatis str. MC2 155] gi|118174829|gb|ABK75725.1| serine/threonine protein kinase [Mycobacterium smegmatis str. MC2 155] Length=493 Score = 275 bits (704), Expect = 1e-71, Method: Compositional matrix adjust. Identities = 143/279 (52%), Positives = 178/279 (64%), Gaps = 23/279 (8%) Query 1 MALASGVTFAGYTVVRMLGCSAMGEVYLVQHPGFPGWQALKVLSPAMAADDEFRRRFQRE 60 M LA+G TFAGY ++R+LG MGEVYL HP P ALKVL +++AD E+R RF RE Sbjct 1 MPLAAGETFAGYNIIRLLGSGGMGEVYLAAHPRLPRQDALKVLPTSISADPEYRERFNRE 60 Query 61 TEVAARLFHPHILEVHDRGEFDGQLWIAMDYVDGIDATQHMADRFPAVLPVGEVLAIVTA 120 +VAA L+HPHI+E+HDRGE DGQLWIAMDYVDG DA + + +++ +P +V IVTA Sbjct 61 ADVAAALWHPHIVEIHDRGEHDGQLWIAMDYVDGTDAARLLKEQYSGGMPPHQVCEIVTA 120 Query 121 VAGALDYAHQRGLLHRDVNPANVVLTSQSAGDQRILLADFGIASQP-------------- 166 +AGALDYAHQRGLLHRDV PAN++L DQRI+LADFGIA Sbjct 121 MAGALDYAHQRGLLHRDVKPANILLGHPGTDDQRIMLADFGIARYADEASGLTATNMTVG 180 Query 167 --SYPAPELSAGADVDGRADQYALALTAIHLFAGAPPVDRSHTGPL-------QPPKLSA 217 +Y APE G +DGRADQYALA TA L G P + S+ + PP + Sbjct 181 TVTYAAPEQLLGNHLDGRADQYALAATAYQLLTGRTPFEHSNPAVVISQHLSAAPPAVGT 240 Query 218 FRPDLARLDGVLSRALATAPADRFGSCREFADAMNEQAG 256 RPDLA LD V ++ALA P DR+ C +FA A+ + G Sbjct 241 HRPDLATLDPVFAKALAKDPRDRYARCADFARALRHRLG 279 >gi|118471062|ref|YP_885289.1| serine/threonine protein kinase [Mycobacterium smegmatis str. MC2 155] gi|118172349|gb|ABK73245.1| serine/threonine-protein kinase PknD [Mycobacterium smegmatis str. MC2 155] Length=496 Score = 272 bits (695), Expect = 2e-70, Method: Compositional matrix adjust. Identities = 144/274 (53%), Positives = 177/274 (65%), Gaps = 23/274 (8%) Query 1 MALASGVTFAGYTVVRMLGCSAMGEVYLVQHPGFPGWQALKVLSPAMAADDEFRRRFQRE 60 M L +G FAGYT+ R+LG MGEVYL +HP P ALK+L ++ D ++R+RF RE Sbjct 1 MPLNTGDVFAGYTIARLLGTGGMGEVYLARHPRLPRQDALKILPTSLTGDTQYRQRFNRE 60 Query 61 TEVAARLFHPHILEVHDRGEFDGQLWIAMDYVDGIDATQHMADRFPAVLPVGEVLAIVTA 120 ++AA L+HPHI+ +HDRGE DGQLWIAMDYVDG DA + + + PA LP + IVTA Sbjct 61 ADIAAGLWHPHIVGLHDRGEADGQLWIAMDYVDGTDAARLVRELHPAGLPPDTAIEIVTA 120 Query 121 VAGALDYAHQRGLLHRDVNPANVVLTSQSAGDQRILLADFGIASQ--------------- 165 +A ALDYAH RGLLHRDV PAN++LT SA +RILLADFG+A + Sbjct 121 IAEALDYAHARGLLHRDVKPANILLTDPSAARRRILLADFGVARRVDDISGLTATNMAVG 180 Query 166 -PSYPAPELSAGADVDGRADQYALALTAIHLFAGAPPVDRSHTGPLQ-------PPKLSA 217 +Y APE G D+DGRADQYALA TA HL AG P S+ + PP+L Sbjct 181 SMAYSAPEQLLGQDLDGRADQYALAATAFHLLAGRSPFHHSNAAVVISKHLSEPPPRLGN 240 Query 218 FRPDLARLDGVLSRALATAPADRFGSCREFADAM 251 RPDLARLD V+ R LA PA RF +C EFA A+ Sbjct 241 SRPDLARLDDVMVRGLAKDPAARFSTCGEFAAAL 274 >gi|145224013|ref|YP_001134691.1| protein kinase [Mycobacterium gilvum PYR-GCK] gi|145216499|gb|ABP45903.1| protein kinase [Mycobacterium gilvum PYR-GCK] Length=450 Score = 271 bits (692), Expect = 3e-70, Method: Compositional matrix adjust. Identities = 146/277 (53%), Positives = 181/277 (66%), Gaps = 27/277 (9%) Query 1 MALASGVTFAGYTVVRMLGCSAMGEVYLVQHPGFPGWQALKVLSPAMAADDEFRRRFQRE 60 M LA+G TFAGYT+VR+LG MGEVYL QHP P ALKVL A++AD E+R+RF+RE Sbjct 1 MPLAAGETFAGYTIVRLLGSGGMGEVYLAQHPRLPRRDALKVLPAAVSADVEYRKRFERE 60 Query 61 TEVAARLFHPHILEVHDRGEFDGQLWIAMDYVDGIDATQHMADRFPAVLPVGEVLAIVTA 120 ++AA L+HPHI+ VHDRGE G++WI+MDYV+G DA +A+ + LPV EV IVTA Sbjct 61 ADIAATLWHPHIVGVHDRGEDAGRIWISMDYVEGADAAHLLAEDYRTGLPVAEVAQIVTA 120 Query 121 VAGALDYAHQRGLLHRDVNPANVVLTSQSAGDQRILLADFGIASQP-------------- 166 VA ALDYAH R LLHRDV PAN+++ + +RI+LADFGIA Sbjct 121 VADALDYAHDRHLLHRDVKPANILIARPDSNTRRIMLADFGIARWDNDISGLTATNMTVG 180 Query 167 --SYPAPELSAGADVDGRADQYALALTAIHLFAGAPPVDRSHTGPL---------QPPKL 215 SY APE G D+DGRADQYALA TA HL G+PP SH+ P P + Sbjct 181 TVSYAAPEQLMGQDLDGRADQYALAATAFHLLTGSPPF--SHSNPAVVISRHLNSAPATV 238 Query 216 SAFRPDLARLDGVLSRALATAPADRFGSCREFADAMN 252 +A RP+LA +D VL+RALA PADR+ C +FA N Sbjct 239 AAHRPELAAVDPVLTRALAKNPADRYPRCADFAREFN 275 >gi|120406577|ref|YP_956406.1| protein kinase [Mycobacterium vanbaalenii PYR-1] gi|119959395|gb|ABM16400.1| serine/threonine protein kinase [Mycobacterium vanbaalenii PYR-1] Length=467 Score = 271 bits (692), Expect = 3e-70, Method: Compositional matrix adjust. Identities = 138/283 (49%), Positives = 183/283 (65%), Gaps = 24/283 (8%) Query 1 MALASGVTFAGYTVVRMLGCSAMGEVYLVQHPGFPGWQALKVLSPAMAADDEFRRRFQRE 60 M L+ G AGYT+VRMLG MG+VYL +HP P + ALKVLS + AD E+R RF RE Sbjct 1 MPLSDGEVIAGYTIVRMLGSGGMGKVYLAKHPRLPRYDALKVLSTTVCADSEYRERFHRE 60 Query 61 TEVAARLFHPHILEVHDRGEFDGQLWIAMDYVDGIDATQHMADRFPAVLPVGEVLAIVTA 120 ++AA L+HPHI+ VHDRGE++G+LWI+MD+V+G DA +A+R+P +P V+ IVTA Sbjct 61 ADIAATLWHPHIVAVHDRGEYEGRLWISMDHVEGTDAAWLLAERYPHGMPPALVIRIVTA 120 Query 121 VAGALDYAHQRGLLHRDVNPANVVLTSQSAGDQRILLADFGIASQ--------------- 165 V ALDYAHQRGLLHRDV PAN+++ ++RI+LADFGIA + Sbjct 121 VGEALDYAHQRGLLHRDVKPANILIADPETENERIMLADFGIARRVGEVSTLTGTSMTVG 180 Query 166 -PSYPAPE-LSAGADVDGRADQYALALTAIHLFAGAPPVDRSHTGPL-------QPPKLS 216 +Y APE L+A +DGRADQYALA TA L G+PP S+ + QPP +S Sbjct 181 TVAYSAPEQLTADEHIDGRADQYALAATAFQLLTGSPPFQHSNPAIVISQHLTAQPPSIS 240 Query 217 AFRPDLARLDGVLSRALATAPADRFGSCREFADAMNEQAGVAI 259 RP+L+ L +ALA +PADRF C +FA A+ ++G + Sbjct 241 VHRPELSSLGMAFEKALAKSPADRFDRCVDFARALANRSGTEL 283 >gi|183982616|ref|YP_001850907.1| anchored-membrane serine/threonine-protein kinase PknF_3 [Mycobacterium marinum M] gi|183175942|gb|ACC41052.1| anchored-membrane serine/threonine-protein kinase PknF_3 [Mycobacterium marinum M] Length=476 Score = 270 bits (689), Expect = 7e-70, Method: Compositional matrix adjust. Identities = 142/279 (51%), Positives = 176/279 (64%), Gaps = 23/279 (8%) Query 1 MALASGVTFAGYTVVRMLGCSAMGEVYLVQHPGFPGWQALKVLSPAMAADDEFRRRFQRE 60 M LA+G TFAGYT+VR LG MGEVYL QHP P ALKVL P ++AD E+R+RF RE Sbjct 1 MPLAAGSTFAGYTIVRQLGTGGMGEVYLAQHPRLPRQDALKVLRPEVSADHEYRQRFHRE 60 Query 61 TEVAARLFHPHILEVHDRGEFDGQLWIAMDYVDGIDATQHMADRFPAVLPVGEVLAIVTA 120 + AA L+HPHI+ VHDRGE DGQLWI MDYVDG DA + DR+P +P EV I+TA Sbjct 61 ADAAAALWHPHIVAVHDRGETDGQLWIDMDYVDGTDAVTLLRDRYPNGMPGSEVSEIITA 120 Query 121 VAGALDYAHQRGLLHRDVNPANVVLTSQSAGDQRILLADFGIA----------------S 164 VA ALDYAH LLHRDV PAN+++ + ++ +RI+LADFGIA Sbjct 121 VAEALDYAHDHKLLHRDVKPANILIAAPASQAKRIMLADFGIAGWVGEASGLTATNMTVG 180 Query 165 QPSYPAPELSAGADVDGRADQYALALTAIHLFAGAPPVDRSHTGPL-------QPPKLSA 217 SY PE G D+DG+ADQYALA TA HL G+PP S+ + PP + Sbjct 181 TVSYAPPEQLMGHDLDGKADQYALAATAYHLLTGSPPFQHSNPAVVISQHLSAAPPAIGQ 240 Query 218 FRPDLARLDGVLSRALATAPADRFGSCREFADAMNEQAG 256 P LA LD V ++ALA P DR+ C +FA A++ + G Sbjct 241 RLPALAELDPVFAKALAKDPKDRYQRCIDFARALSHRLG 279 >gi|315444348|ref|YP_004077227.1| serine/threonine protein kinase [Mycobacterium sp. Spyr1] gi|315262651|gb|ADT99392.1| serine/threonine protein kinase [Mycobacterium sp. Spyr1] Length=450 Score = 270 bits (689), Expect = 7e-70, Method: Compositional matrix adjust. Identities = 145/277 (53%), Positives = 181/277 (66%), Gaps = 27/277 (9%) Query 1 MALASGVTFAGYTVVRMLGCSAMGEVYLVQHPGFPGWQALKVLSPAMAADDEFRRRFQRE 60 M LA+G TFAGYT+VR+LG MGEVYL QHP P ALKVL +++AD E+R+RF+RE Sbjct 1 MPLAAGETFAGYTIVRLLGSGGMGEVYLAQHPRLPRRDALKVLPASVSADVEYRKRFERE 60 Query 61 TEVAARLFHPHILEVHDRGEFDGQLWIAMDYVDGIDATQHMADRFPAVLPVGEVLAIVTA 120 ++AA L+HPHI+ VHDRGE G++WI+MDYV+G DA +A+ + LPV EV IVTA Sbjct 61 ADIAATLWHPHIVGVHDRGEDAGRIWISMDYVEGADAAHLLAEDYRTGLPVAEVAQIVTA 120 Query 121 VAGALDYAHQRGLLHRDVNPANVVLTSQSAGDQRILLADFGIASQP-------------- 166 VA ALDYAH R LLHRDV PAN+++ + +RI+LADFGIA Sbjct 121 VADALDYAHDRHLLHRDVKPANILIARPDSNTRRIMLADFGIARWDNDISGLTATNMTVG 180 Query 167 --SYPAPELSAGADVDGRADQYALALTAIHLFAGAPPVDRSHTGPL---------QPPKL 215 SY APE G D+DGRADQYALA TA HL G+PP SH+ P P + Sbjct 181 TVSYAAPEQLMGQDLDGRADQYALAATAFHLLTGSPPF--SHSNPAVVISRHLNSAPATV 238 Query 216 SAFRPDLARLDGVLSRALATAPADRFGSCREFADAMN 252 +A RP+LA +D VL+RALA PADR+ C +FA N Sbjct 239 AAHRPELAAVDPVLTRALAKNPADRYPRCADFAREFN 275 >gi|240167979|ref|ZP_04746638.1| anchored-membrane serine/threonine-protein kinase PknF_1 [Mycobacterium kansasii ATCC 12478] Length=504 Score = 270 bits (689), Expect = 8e-70, Method: Compositional matrix adjust. Identities = 139/272 (52%), Positives = 181/272 (67%), Gaps = 24/272 (8%) Query 3 LASGVTFAGYTVVRMLGCSAMGEVYLVQHPGFPGWQALKVLSPAMAADDEFRRRFQRETE 62 L+ G FAGYT+VR LG MGEVYL QHP P ALK+L + D EFR+RF RE + Sbjct 11 LSEGELFAGYTIVRRLGAGGMGEVYLAQHPRLPRRDALKILPRELTGDLEFRQRFNREAD 70 Query 63 VAARLFHPHILEVHDRGEFDGQLWIAMDYVDGIDATQHMADRFPAVLPVGEVLAIVTAVA 122 +AA L++ HI+ +HDRGEF GQLWI+MDYV+G DA Q + R+P+ +P +V+ I++AVA Sbjct 71 LAASLYNEHIVGIHDRGEFQGQLWISMDYVEGTDAAQLLRSRYPSGMPHPDVVEIISAVA 130 Query 123 GALDYAHQRGLLHRDVNPANVVLTSQSAGDQRILLADFGIASQ----------------P 166 ALDYAH RGLLHRDV PAN++L ++ +RILLADFGIA Q Sbjct 131 DALDYAHSRGLLHRDVKPANILL-GEAMPRRRILLADFGIARQLGEISGLTATNMLMGTT 189 Query 167 SYPAPELSAGADVDGRADQYALALTAIHLFAGAPPVDRSHTGPLQ-------PPKLSAFR 219 +Y APE GAD+DGRADQYAL TA HL AG+ P S+ + PP +S +R Sbjct 190 AYCAPEQLQGADLDGRADQYALGCTAFHLLAGSAPFQHSNPAVVISQHLSSPPPSISTWR 249 Query 220 PDLARLDGVLSRALATAPADRFGSCREFADAM 251 P+LA LDGV+++ALA PA+R+ +C +FA A+ Sbjct 250 PELAHLDGVIAKALAKDPAERYPTCADFAAAL 281 >gi|240172044|ref|ZP_04750703.1| anchored-membrane serine/threonine-protein kinase [Mycobacterium kansasii ATCC 12478] Length=635 Score = 269 bits (688), Expect = 9e-70, Method: Compositional matrix adjust. Identities = 209/591 (36%), Positives = 276/591 (47%), Gaps = 113/591 (19%) Query 1 MALASGVTFAGYTVVRMLGCSAMGEVYLVQHPGFPGWQALKVLSPAMAADDEFRRRFQRE 60 M+L G FAGYTV+R+LG MG VYL +HP P ALKVL + D E+R RF RE Sbjct 1 MSLEVGQVFAGYTVLRVLGAGGMGRVYLARHPRLPREDALKVLPSDLTTDAEYRARFLRE 60 Query 61 TEVAARLFHPHILEVHDRGEFDGQLWIAMDYVDGIDATQHMADRFPAVLPVGEVLAIVTA 120 ++AA L HPHI+ +HDRGE DG LWI+MDYV GID + + D +P +P+ EV+ I+TA Sbjct 61 ADLAAGLSHPHIVRIHDRGEEDGHLWISMDYVAGIDLGRLLQDSYPGGMPLDEVVPIITA 120 Query 121 VAGALDYAHQRGLLHRDVNPANVVLTSQSAGDQRILLADFGIA----------------S 164 VA ALDY+H RGLLHRDV PAN++L R+ LADFGIA Sbjct 121 VASALDYSHHRGLLHRDVKPANILLAEPDGQAPRVFLADFGIARPIEDATRLTATDMMVG 180 Query 165 QPSYPAPELSAGADVDGRADQYALALTAIHLFAGAPPVDRSHTGPLQ-------PPKLSA 217 +Y APE GA VDG ADQYALA TA L G PP S++ + P + A Sbjct 181 TAAYAAPEQLKGASVDGCADQYALACTAFQLLTGMPPYAGSNSAVVITKHLSAPSPSIGA 240 Query 218 FRPDLARLDGVLSRALATAPADRFGSCREFADAMNEQAGVAIADQSSGGVDASEVTAAAG 277 + P LA LD V ++ALA P+ RF SC EFA+ + Q G ++ Sbjct 241 YHPLLAGLDPVFAKALAKDPSHRFSSCGEFAEHLGRQLGPGLS----------------- 283 Query 278 EEAYVVDYPAYGWPEAVDCKEPSARAPAPAAPTPQRRGSMLQSAAGVLARRLDNFSTATK 337 A + +P +P APA P R Sbjct 284 -SAVAIPFPD---------TQPEIDVTAPARTAPAR------------------------ 309 Query 338 APASPTRRRPRR---ILVGAVA--VLLLA-GLFAVGIVIGRKTNTTATEVARPPTSGSAV 391 PT R RR L+GAVA VLL+A G+FA+ + + R T A P S S Sbjct 310 ----PTGRAVRRHPGFLIGAVASIVLLVAGGIFAI-VKLTRHHQT-----AGAPHSAS-T 358 Query 392 PSAPTTTVAVTAPVPLDGTYRIEIQRSKQTYDYTPTPQPPDVNTWWAFRTSCTPTECLAA 451 P+ P A T P G YR++ + + P P +A R+ C C+A Sbjct 359 PTNPAPAAANTG--PFTGVYRVQFGPVTKLAE-APAPGAMQSTDTYAIRSMCGSAGCVAT 415 Query 452 ATMLDDNDHTQAKTPPVRPFLMQFGEGQWKSRPETVQFPCVGPNGSPSTQATTQLLALRP 511 AT L + + P F + G G+W V S ++ L+P Sbjct 416 ATRLSG----EVRLAPSTVF-DEVG-GRW------VAVTIGSAKCRDSASRMWEVFTLQP 463 Query 512 QPQGDLVGEMVVTVHSNECGQQGAVIRIPAVASRSGDLPPAVTVPDPATIP 562 P G GE SN C ++ V +R+GD+ ++PDPA +P Sbjct 464 GPNGTFTGEYRGAA-SNSCAEKRTV-----TFTRTGDV-DVNSLPDPAALP 507 >gi|108801281|ref|YP_641478.1| serine/threonine protein kinase [Mycobacterium sp. MCS] gi|119870432|ref|YP_940384.1| protein kinase [Mycobacterium sp. KMS] gi|108771700|gb|ABG10422.1| serine/threonine protein kinase [Mycobacterium sp. MCS] gi|119696521|gb|ABL93594.1| protein kinase [Mycobacterium sp. KMS] Length=587 Score = 269 bits (688), Expect = 9e-70, Method: Compositional matrix adjust. Identities = 173/384 (46%), Positives = 216/384 (57%), Gaps = 41/384 (10%) Query 1 MALASGVTFAGYTVVRMLGCSAMGEVYLVQHPGFPGWQALKVLSPAMAADDEFRRRFQRE 60 M L +G FAGYT+VR++G MGEVYL QHP P ALKVL + +ADDE+R RF RE Sbjct 1 MPLETGQVFAGYTIVRLVGTGGMGEVYLAQHPRLPRQDALKVLPASFSADDEYRHRFSRE 60 Query 61 TEVAARLFHPHILEVHDRGEFDGQLWIAMDYVDGIDATQHMADRFPAVLPVGEVLAIVTA 120 ++AA L+HPHI+ VHDRGE+DG+LWI+MD+VDG DA + + DR+P LP +V+ IVTA Sbjct 61 ADLAAALWHPHIVGVHDRGEYDGRLWISMDFVDGHDAARLLVDRYPNGLPAADVIEIVTA 120 Query 121 VAGALDYAHQRGLLHRDVNPANVVLTSQSAGDQRILLADFGIASQP-------------- 166 VA ALDYAHQR LLHRDV PAN+++T +RILLADFGIA Sbjct 121 VADALDYAHQRQLLHRDVKPANILITGPDRARRRILLADFGIARHAEDNTGLTSSNIAVG 180 Query 167 --SYPAPELSAGADVDGRADQYALALTAIHLFAGAPP-------VDRSHTGPLQPPKLSA 217 SY APE G +DGRADQY+LA TA LF G+PP V SH PP+L Sbjct 181 SMSYSAPEQLMGHPIDGRADQYSLAATAYRLFTGSPPFPHSNPAVIISHHLNTPPPRLGD 240 Query 218 FRPDLARLDGVLSRALATAPADRFGSCREFADAMNEQAGVAIADQSSGGVDASEVTAAAG 277 RP+L D ++RALA PA RFGSC +FA A+ + G A S + Sbjct 241 TRPELRAFDAAMARALAKDPAARFGSCHDFAVALAQATGSPAAPPS-----LATAPPGPV 295 Query 278 EEAYVVDYPAYGWPEAVDCKEPSARAPAPAAPTPQRRGSMLQSAAGVLARRLDNFSTATK 337 V YP G P + +P A P P + S A + + A Sbjct 296 GPPPGVSYP--GPPISAPPAQPQMGAAGP----PVMVSPWMPSGAPYPGTQ---YGPAQG 346 Query 338 APASPTRRRPRRILVGAV-AVLLL 360 P P RRR I+ GA+ AV+LL Sbjct 347 QP--PPRRR-GLIVAGAILAVILL 367 >gi|183982944|ref|YP_001851235.1| membrane-anchored serine/threonine-protein kinase [Mycobacterium marinum M] gi|183176270|gb|ACC41380.1| membrane-anchored serine/threonine-protein kinase [Mycobacterium marinum M] Length=654 Score = 268 bits (686), Expect = 1e-69, Method: Compositional matrix adjust. Identities = 156/340 (46%), Positives = 196/340 (58%), Gaps = 35/340 (10%) Query 1 MALASGVTFAGYTVVRMLGCSAMGEVYLVQHPGFPGWQALKVLSPAMAADDEFRRRFQRE 60 M L G FAGY + R+LG MGEVYL QHP P ALK+LS DDEFR RF RE Sbjct 1 MPLNEGDIFAGYVIQRLLGTGGMGEVYLAQHPRLPRLDALKILSLDATDDDEFRARFTRE 60 Query 61 TEVAARLFHPHILEVHDRGEFDGQLWIAMDYVDGIDATQHMADRFPAVLPVGEVLAIVTA 120 E+AA L+HPHI+ VHDRGEFDG+LWI+MDYVDG DA + R+ + +P+ +V+ IVTA Sbjct 61 AELAATLWHPHIVGVHDRGEFDGRLWISMDYVDGTDARHLVEQRYRSGMPLEDVIEIVTA 120 Query 121 VAGALDYAHQRGLLHRDVNPANVVLTSQS-AGDQRILLADFGIASQ-------------- 165 VA ALD+AH+R LLHRDV PAN+++T S + +R+LL DFGIA + Sbjct 121 VAEALDFAHERRLLHRDVKPANILVTEPSESARRRVLLTDFGIAREIDDKHRLTEAQMAI 180 Query 166 --PSYPAPELSAGADVDGRADQYALALTAIHLFAGAPPVDRSHTG-------PLQPPKLS 216 +Y APE G +DGRADQYALA TA HL AG PP D S+ + PP++S Sbjct 181 GTVAYAAPEQLTGKPLDGRADQYALAATAFHLLAGVPPFDHSNRAVVVGQHLNMPPPRIS 240 Query 217 AFRPDLARLDGVLSRALATAPADRFGSCREFADAMNEQAGVAIADQSSGGVDASEVTAAA 276 P LA LD ++ALA P DR+ C +FA A+ G Q+ G ++E Sbjct 241 KRHPKLAHLDAAFAKALAKDPDDRYPRCIDFAKALAAGPGSIAEHQARRGATSTE----- 295 Query 277 GEEAYVVDYPAYGWPEAVDCKEPSARAP-APAAPTPQRRG 315 D A EA++ PS AP A A P P G Sbjct 296 -----PFDVNAEMSAEALEPARPSGTAPSAQAQPHPSEAG 330 >gi|118617740|ref|YP_906072.1| membrane-anchored serine/threonine-protein kinase [Mycobacterium ulcerans Agy99] gi|118569850|gb|ABL04601.1| membrane-anchored serine/threonine-protein kinase [Mycobacterium ulcerans Agy99] Length=654 Score = 266 bits (681), Expect = 7e-69, Method: Compositional matrix adjust. Identities = 155/340 (46%), Positives = 195/340 (58%), Gaps = 35/340 (10%) Query 1 MALASGVTFAGYTVVRMLGCSAMGEVYLVQHPGFPGWQALKVLSPAMAADDEFRRRFQRE 60 M L G FAGY + R+LG MGEVYL QHP P ALK+LS DDEFR RF RE Sbjct 1 MPLNEGDIFAGYVIQRLLGTGGMGEVYLAQHPRLPRLDALKILSLDATDDDEFRARFTRE 60 Query 61 TEVAARLFHPHILEVHDRGEFDGQLWIAMDYVDGIDATQHMADRFPAVLPVGEVLAIVTA 120 E+AA L+HPHI+ VHDRGEFDG+LWI+MDYVDG D + R+ + +P+ +V+ IVTA Sbjct 61 AELAATLWHPHIVGVHDRGEFDGRLWISMDYVDGTDTRHLVEQRYRSGMPLEDVIEIVTA 120 Query 121 VAGALDYAHQRGLLHRDVNPANVVLTSQS-AGDQRILLADFGIASQ-------------- 165 VA ALD+AH+R LLHRDV PAN+++T S + +R+LL DFGIA + Sbjct 121 VAEALDFAHERRLLHRDVKPANILVTEPSESARRRVLLTDFGIAREIDDKHRLTEAQMAI 180 Query 166 --PSYPAPELSAGADVDGRADQYALALTAIHLFAGAPPVDRSHTG-------PLQPPKLS 216 +Y APE G +DGRADQYALA TA HL AG PP D S+ + PP++S Sbjct 181 GTVAYAAPEQLTGRPLDGRADQYALAATAFHLLAGVPPFDHSNRAVVVGQHLNMPPPRIS 240 Query 217 AFRPDLARLDGVLSRALATAPADRFGSCREFADAMNEQAGVAIADQSSGGVDASEVTAAA 276 P LA LD ++ALA P DR+ C +FA A+ G Q+ G ++E Sbjct 241 KRHPKLAHLDAAFAKALAKDPDDRYPRCIDFAKALAAGPGSIAEHQARRGATSTE----- 295 Query 277 GEEAYVVDYPAYGWPEAVDCKEPSARAP-APAAPTPQRRG 315 D A EA++ PS AP A A P P G Sbjct 296 -----PFDVNAEMSAEALEPARPSGTAPSAQAQPHPSEAG 330 >gi|31792934|ref|NP_855427.1| anchored-membrane serine/threonine-protein kinase PKNF (protein kinase F) (STPK F) [Mycobacterium bovis AF2122/97] gi|121637654|ref|YP_977877.1| anchored-membrane serine/threonine-protein kinase pknF [Mycobacterium bovis BCG str. Pasteur 1173P2] gi|224990129|ref|YP_002644816.1| anchored-membrane serine/threonine-protein kinase [Mycobacterium bovis BCG str. Tokyo 172] gi|61214285|sp|Q7TZN1.1|PKNF_MYCBO RecName: Full=Serine/threonine-protein kinase pknF gi|31618525|emb|CAD94477.1| ANCHORED-MEMBRANE SERINE/THREONINE-PROTEIN KINASE PKNF (PROTEIN KINASE F) (STPK F) [Mycobacterium bovis AF2122/97] gi|121493301|emb|CAL71772.1| Anchored-membrane serine/threonine-protein kinase pknF [Mycobacterium bovis BCG str. Pasteur 1173P2] gi|224773242|dbj|BAH26048.1| anchored-membrane serine/threonine-protein kinase [Mycobacterium bovis BCG str. Tokyo 172] gi|341601672|emb|CCC64345.1| Anchored-membrane serine/threonine-protein kinase pknF [Mycobacterium bovis BCG str. Moreau RDJ] Length=476 Score = 265 bits (678), Expect = 1e-68, Method: Compositional matrix adjust. Identities = 141/281 (51%), Positives = 174/281 (62%), Gaps = 27/281 (9%) Query 1 MALASGVTFAGYTVVRMLGCSAMGEVYLVQHPGFPGWQALKVLSPAMAADDEFRRRFQRE 60 M LA G TFAG+T+VR LG MGEVYL +HP P ALKVL ++AD E+R RF RE Sbjct 1 MPLAEGSTFAGFTIVRQLGSGGMGEVYLARHPRLPRQDALKVLRADVSADGEYRARFNRE 60 Query 61 TEVAARLFHPHILEVHDRGEFDGQLWIAMDYVDGIDATQHMADRFPAVLPVGEVLAIVTA 120 + AA L+HPHI+ VHDRGEFDGQLWI MD+VDG D + DR+P +P EV I+TA Sbjct 61 ADAAASLWHPHIVAVHDRGEFDGQLWIDMDFVDGTDTVSLLRDRYPNGMPGPEVTEIITA 120 Query 121 VAGALDYAHQRGLLHRDVNPANVVLTSQSAGDQRILLADFGIA----------------S 164 VA ALDYAH+R LLHRDV PAN+++ + + D+RI+LADFGIA Sbjct 121 VAEALDYAHERRLLHRDVKPANILIANPDSPDRRIMLADFGIAGWVDDPSGLTATNMTVG 180 Query 165 QPSYPAPELSAGADVDGRADQYALALTAIHLFAGAPPVDRSHTGP---------LQPPKL 215 SY APE G ++DGRADQYALA TA HL G+PP H P PP + Sbjct 181 TVSYAAPEQLMGNELDGRADQYALAATAFHLLTGSPPF--QHANPAVVISQHLSASPPAI 238 Query 216 SAFRPDLARLDGVLSRALATAPADRFGSCREFADAMNEQAG 256 P+L LD V ++ALA P DR+ C +FA A+ + G Sbjct 239 GDRVPELTPLDPVFAKALAKQPKDRYQRCVDFARALGHRLG 279 >gi|15608884|ref|NP_216262.1| anchored-membrane serine/threonine-protein kinase PKNF (protein kinase F) (STPK F) [Mycobacterium tuberculosis H37Rv] gi|15841210|ref|NP_336247.1| serine/threonine protein kinase [Mycobacterium tuberculosis CDC1551] gi|148661545|ref|YP_001283068.1| serine/threonine protein kinase [Mycobacterium tuberculosis H37Ra] 70 more sequence titles Length=476 Score = 265 bits (678), Expect = 1e-68, Method: Compositional matrix adjust. Identities = 139/279 (50%), Positives = 175/279 (63%), Gaps = 23/279 (8%) Query 1 MALASGVTFAGYTVVRMLGCSAMGEVYLVQHPGFPGWQALKVLSPAMAADDEFRRRFQRE 60 M LA G TFAG+T+VR LG MGEVYL +HP P ALKVL ++AD E+R RF RE Sbjct 1 MPLAEGSTFAGFTIVRQLGSGGMGEVYLARHPRLPRQDALKVLRADVSADGEYRARFNRE 60 Query 61 TEVAARLFHPHILEVHDRGEFDGQLWIAMDYVDGIDATQHMADRFPAVLPVGEVLAIVTA 120 + AA L+HPHI+ VHDRGEFDGQLWI MD+VDG D + DR+P +P EV I+TA Sbjct 61 ADAAASLWHPHIVAVHDRGEFDGQLWIDMDFVDGTDTVSLLRDRYPNGMPGPEVTEIITA 120 Query 121 VAGALDYAHQRGLLHRDVNPANVVLTSQSAGDQRILLADFGIA----------------S 164 VA ALDYAH+R LLHRDV PAN+++ + + D+RI+LADFGIA Sbjct 121 VAEALDYAHERRLLHRDVKPANILIANPDSPDRRIMLADFGIAGWVDDPSGLTATNMTVG 180 Query 165 QPSYPAPELSAGADVDGRADQYALALTAIHLFAGAPPVDRSHTGPL-------QPPKLSA 217 SY APE G ++DGRADQYALA TA HL G+PP ++ + PP + Sbjct 181 TVSYAAPEQLMGNELDGRADQYALAATAFHLLTGSPPFQHANPAVVISQHLSASPPAIGD 240 Query 218 FRPDLARLDGVLSRALATAPADRFGSCREFADAMNEQAG 256 P+L LD V ++ALA P DR+ C +FA A+ + G Sbjct 241 RVPELTPLDPVFAKALAKQPKDRYQRCVDFARALGHRLG 279 >gi|126437951|ref|YP_001073642.1| serine/threonine protein kinase [Mycobacterium sp. JLS] gi|126237751|gb|ABO01152.1| serine/threonine protein kinase [Mycobacterium sp. JLS] Length=431 Score = 265 bits (676), Expect = 2e-68, Method: Compositional matrix adjust. Identities = 139/281 (50%), Positives = 179/281 (64%), Gaps = 27/281 (9%) Query 1 MALASGVTFAGYTVVRMLGCSAMGEVYLVQHPGFPGWQALKVLSPAMAADDEFRRRFQRE 60 M LA G AGYT++R LG MGEVYL QHP P ALKVL+ A++ADDE+R+RFQRE Sbjct 1 MPLAEGEVIAGYTIMRSLGHGGMGEVYLAQHPRLPRQDALKVLTAAVSADDEYRQRFQRE 60 Query 61 TEVAARLFHPHILEVHDRGEFDGQLWIAMDYVDGIDATQHMADRFPAVLPVGEVLAIVTA 120 ++AA L+HPHI+ VHDRG+FDG LWI+MD+V G DA + +A+R+P +P V+ I+TA Sbjct 61 ADIAATLWHPHIVSVHDRGDFDGLLWISMDFVQGTDAARLLAERYPNGMPPDVVVRIITA 120 Query 121 VAGALDYAHQRGLLHRDVNPANVVLTSQSAGDQRILLADFGIASQP-------------- 166 VA ALD+AH+RGL HRDV PAN+++ + + D+R +LADFGIA Q Sbjct 121 VASALDHAHERGLYHRDVKPANILIANPGSPDERAMLADFGIARQAGDASGLTGTNMTVG 180 Query 167 --SYPAPELSAGADVDGRADQYALALTAIHLFAGAPPVDRSHTGPL---------QPPKL 215 +Y APE G +DGRADQYALA TA L G PP +HT P PP + Sbjct 181 TVAYAAPEQLRGDHIDGRADQYALAATAYQLLTGTPPF--THTNPAVVISAHLTSDPPVI 238 Query 216 SAFRPDLARLDGVLSRALATAPADRFGSCREFADAMNEQAG 256 RP+L+ L V RALA +P RF C +FA A+ + G Sbjct 239 GDVRPELSGLGPVFGRALAKSPDKRFERCVDFARALEHRIG 279 >gi|108801970|ref|YP_642167.1| serine/threonine protein kinase [Mycobacterium sp. MCS] gi|119871122|ref|YP_941074.1| serine/threonine protein kinase [Mycobacterium sp. KMS] gi|108772389|gb|ABG11111.1| serine/threonine protein kinase [Mycobacterium sp. MCS] gi|119697211|gb|ABL94284.1| serine/threonine protein kinase [Mycobacterium sp. KMS] Length=430 Score = 265 bits (676), Expect = 2e-68, Method: Compositional matrix adjust. Identities = 139/281 (50%), Positives = 179/281 (64%), Gaps = 27/281 (9%) Query 1 MALASGVTFAGYTVVRMLGCSAMGEVYLVQHPGFPGWQALKVLSPAMAADDEFRRRFQRE 60 M LA G AGYT++R LG MGEVYL QHP P ALKVL+ A++ADDE+R+RFQRE Sbjct 1 MPLAEGEVIAGYTIMRSLGHGGMGEVYLAQHPRLPRQDALKVLTAAVSADDEYRQRFQRE 60 Query 61 TEVAARLFHPHILEVHDRGEFDGQLWIAMDYVDGIDATQHMADRFPAVLPVGEVLAIVTA 120 ++AA L+HPHI+ VHDRG+FDG LWI+MD+V G DA + +A+R+P +P V+ I+TA Sbjct 61 ADIAATLWHPHIVSVHDRGDFDGLLWISMDFVQGTDAARLLAERYPNGMPPDVVVRIITA 120 Query 121 VAGALDYAHQRGLLHRDVNPANVVLTSQSAGDQRILLADFGIASQP-------------- 166 VA ALD+AH+RGL HRDV PAN+++ + + D+R +LADFGIA Q Sbjct 121 VASALDHAHERGLYHRDVKPANILIANPGSPDERAMLADFGIARQAGDASGLTGTNMTVG 180 Query 167 --SYPAPELSAGADVDGRADQYALALTAIHLFAGAPPVDRSHTGPL---------QPPKL 215 +Y APE G +DGRADQYALA TA L G PP +HT P PP + Sbjct 181 TVAYAAPEQLRGDHIDGRADQYALAATAYQLLTGTPPF--THTNPAVVISAHLTSDPPVI 238 Query 216 SAFRPDLARLDGVLSRALATAPADRFGSCREFADAMNEQAG 256 RP+L+ L V RALA +P RF C +FA A+ + G Sbjct 239 GDVRPELSGLGPVFGRALAKSPDKRFERCVDFARALEHRIG 279 >gi|183984145|ref|YP_001852436.1| anchored-membrane serine/threonine-protein kinase PknF [Mycobacterium marinum M] gi|183177471|gb|ACC42581.1| anchored-membrane serine/threonine-protein kinase PknF [Mycobacterium marinum M] Length=495 Score = 264 bits (675), Expect = 3e-68, Method: Compositional matrix adjust. Identities = 156/281 (56%), Positives = 187/281 (67%), Gaps = 28/281 (9%) Query 1 MALASGVTFAGYTVVRMLGCSAMGEVYLVQHPGFPGWQALKVLSPAMAADDEFRRRFQRE 60 M L G FAGYT+V +LG AMGEVYL QHP P ALKVL P ++AD FR RFQRE Sbjct 1 MPLPPGSAFAGYTIVGLLGSGAMGEVYLAQHPRLPRRDALKVLPPDVSADTAFRERFQRE 60 Query 61 TEVAARLFHPHILEVHDRGEFDGQLWIAMDYVDGIDATQHMADRFPAVLPVGEVLAIVTA 120 ++AA LFHPHI+ VHDRGEF+GQLWI+MDY++G DA + ++PA +PV EV+A+VTA Sbjct 61 ADLAATLFHPHIVGVHDRGEFNGQLWISMDYIEGTDAAALIRSQYPAGMPVAEVVAVVTA 120 Query 121 VAGALDYAHQRGLLHRDVNPANVVLTS-QSAGDQRILLADFGIASQ-------------- 165 VAGALDYAHQRGLLHRDV PAN++LT +AG RI LADFGIA Q Sbjct 121 VAGALDYAHQRGLLHRDVKPANILLTGPDNAGGPRIFLADFGIARQLDDISGITATNLTV 180 Query 166 --PSYPAPELSAGADVDGRADQYALALTAIHLFAGAPPVDRSH---------TGPLQPPK 214 +Y APE GADVDGRADQYALA TA HL GAPP ++ T P PP Sbjct 181 GTAAYAAPEQLTGADVDGRADQYALAATAFHLLTGAPPYQHANSVAVISQHLTAP--PPA 238 Query 215 LSAFRPDLARLDGVLSRALATAPADRFGSCREFADAMNEQA 255 L RP+LA LD V + ALA P +R+ C +FA A+++ A Sbjct 239 LGDRRPELAPLDRVFAAALAKQPNERYWRCADFAQALSQVA 279 >gi|118472741|ref|YP_885582.1| serine/threonine protein kinase [Mycobacterium smegmatis str. MC2 155] gi|118174028|gb|ABK74924.1| serine/threonine-protein kinase PknD [Mycobacterium smegmatis str. MC2 155] Length=624 Score = 264 bits (674), Expect = 4e-68, Method: Compositional matrix adjust. Identities = 137/278 (50%), Positives = 176/278 (64%), Gaps = 25/278 (8%) Query 1 MALASGVTFAGYTVVRMLGCSAMGEVYLVQHPGFPGWQALKVLSPAMAADDEFRRRFQRE 60 MAL+ G AGYTV RMLG MGEVYL QHP P ALKVL ++AD + RF +E Sbjct 1 MALSQGAKIAGYTVERMLGSGGMGEVYLAQHPRLPRHDALKVLRANISADPAYVERFNKE 60 Query 61 TEVAARLFHPHILEVHDRGEFDGQLWIAMDYVDGIDATQHMADRFPAVLPVGEVLAIVTA 120 ++AA+L+HPHI+ +HDRG+ +LWI+MD+VDG DA++ + DR+P +PV EVL IV A Sbjct 61 ADLAAKLWHPHIVGIHDRGKHRNRLWISMDFVDGTDASRLLHDRYPDGMPVPEVLDIVKA 120 Query 121 VAGALDYAHQRGLLHRDVNPANVVLTSQSAGDQRILLADFGIASQ--------------- 165 VA ALDYAH RGLLHRDV PAN++++ G++RILL DFG+A Sbjct 121 VAAALDYAHGRGLLHRDVKPANILISDGDHGERRILLGDFGVARDLGDSAGNGLTATNMT 180 Query 166 ---PSYPAPELSAGADVDGRADQYALALTAIHLFAGAPPVDRSHTGPLQ-------PPKL 215 +Y APE G ++DGRADQY+LA TA HL G P + S+ + PP L Sbjct 181 VGTAAYAAPEQLMGLELDGRADQYSLAATAYHLLTGGPLFENSNPAVVIGQHLNAPPPAL 240 Query 216 SAFRPDLARLDGVLSRALATAPADRFGSCREFADAMNE 253 RP+LA LD LSRALA P DRF +C +FA+A+ Sbjct 241 GDSRPELAPLDAALSRALAKNPDDRFATCTDFANALEH 278 >gi|342860823|ref|ZP_08717473.1| anchored-membrane serine/threonine-protein kinase PknF_1 [Mycobacterium colombiense CECT 3035] gi|342131847|gb|EGT85104.1| anchored-membrane serine/threonine-protein kinase PknF_1 [Mycobacterium colombiense CECT 3035] Length=508 Score = 261 bits (666), Expect = 3e-67, Method: Compositional matrix adjust. Identities = 137/276 (50%), Positives = 182/276 (66%), Gaps = 24/276 (8%) Query 3 LASGVTFAGYTVVRMLGCSAMGEVYLVQHPGFPGWQALKVLSPAMAADDEFRRRFQRETE 62 L G FAGYT+VR LG MG+VYL HP P ALKVLS + A+DEFR+RF RE + Sbjct 11 LTPGQVFAGYTIVRRLGAGGMGQVYLAAHPRLPRRDALKVLSGELTANDEFRQRFNREAD 70 Query 63 VAARLFHPHILEVHDRGEFDGQLWIAMDYVDGIDATQHMADRFPAVLPVGEVLAIVTAVA 122 +AA L++ HI+ +HDRGEFDG+LW++MDYV+GIDA++ + R+P+ +P EV+ I++AVA Sbjct 71 LAASLYNEHIVGIHDRGEFDGKLWLSMDYVEGIDASELLHSRYPSGMPKVEVVEIISAVA 130 Query 123 GALDYAHQRGLLHRDVNPANVVLTSQSAGDQRILLADFGIASQ----------------P 166 ALDYAH RGLLHRDV PAN++L + +RILLADFGIA + Sbjct 131 DALDYAHSRGLLHRDVKPANILL-GDAHPRRRILLADFGIARELGEISGLTATNMLVGTT 189 Query 167 SYPAPELSAGADVDGRADQYALALTAIHLFAGAPPVDRSHTGPLQ-------PPKLSAFR 219 +Y APE GAD+D RADQYAL TA +L G+ P S+ + PP +S R Sbjct 190 AYCAPEQLQGADLDARADQYALGCTAYNLLTGSAPFHHSNPAVVIGQHLSAPPPLISQRR 249 Query 220 PDLARLDGVLSRALATAPADRFGSCREFADAMNEQA 255 P+LA LD V+++ALA P+DR+ SC +FA A+ +A Sbjct 250 PELAELDPVIAKALAKHPSDRYASCTDFAAALAGRA 285 >gi|183982422|ref|YP_001850713.1| anchored-membrane serine/threonine-protein kinase PknF_1 [Mycobacterium marinum M] gi|183175748|gb|ACC40858.1| anchored-membrane serine/threonine-protein kinase PknF_1 [Mycobacterium marinum M] Length=504 Score = 260 bits (665), Expect = 4e-67, Method: Compositional matrix adjust. Identities = 138/277 (50%), Positives = 177/277 (64%), Gaps = 28/277 (10%) Query 3 LASGVTFAGYTVVRMLGCSAMGEVYLVQHPGFPGWQALKVLSPAMAADDEFRRRFQRETE 62 L G FAGYT+VR LG MGEVYL QHP P ALK+L + EFR+RF RE + Sbjct 11 LQEGELFAGYTIVRRLGAGGMGEVYLAQHPRLPRRDALKILPAEFTSSQEFRQRFNREAD 70 Query 63 VAARLFHPHILEVHDRGEFDGQLWIAMDYVDGIDATQHMADRFPAVLPVGEVLAIVTAVA 122 +AA L++ HI+ +HDRGEF GQLWI+MDYV+G DA + + ++P +P EV+ I+ AVA Sbjct 71 LAATLYNQHIVGIHDRGEFHGQLWISMDYVEGTDAARLLNTQYPTGMPYAEVVEIIAAVA 130 Query 123 GALDYAHQRGLLHRDVNPANVVLTSQSAGDQRILLADFGIASQ----------------P 166 ALDYAH +GLLHRDV PAN++L ++ +RI+LADFGIA + Sbjct 131 DALDYAHSQGLLHRDVKPANILL-GEANHRRRIVLADFGIAREVGAISGLTATNMLMGTT 189 Query 167 SYPAPELSAGADVDGRADQYALALTAIHLFAGAPPVDRSHTGPLQ---------PPKLSA 217 +Y APE GA +DGRADQYAL TA HL AG+ P HT P PP +SA Sbjct 190 AYCAPEQLQGAPLDGRADQYALGCTAFHLLAGSAPFQ--HTNPAVIITQHLSAPPPLISA 247 Query 218 FRPDLARLDGVLSRALATAPADRFGSCREFADAMNEQ 254 RP+LA LDGV++RALA PA+R+ +C +FA A+ Q Sbjct 248 RRPELAHLDGVIARALAKNPAERYPTCSDFAAALAGQ 284 >gi|118619584|ref|YP_907916.1| anchored-membrane serine/threonine-protein kinase PknF [Mycobacterium ulcerans Agy99] gi|118571694|gb|ABL06445.1| anchored-membrane serine/threonine-protein kinase PknF [Mycobacterium ulcerans Agy99] Length=495 Score = 259 bits (662), Expect = 1e-66, Method: Compositional matrix adjust. Identities = 154/281 (55%), Positives = 185/281 (66%), Gaps = 28/281 (9%) Query 1 MALASGVTFAGYTVVRMLGCSAMGEVYLVQHPGFPGWQALKVLSPAMAADDEFRRRFQRE 60 M L G FAGYT+V +LG AMGEVYL QHP P ALKVL P ++AD FR RFQRE Sbjct 1 MPLPPGSAFAGYTIVGLLGSGAMGEVYLAQHPRLPRRDALKVLPPDVSADTAFRERFQRE 60 Query 61 TEVAARLFHPHILEVHDRGEFDGQLWIAMDYVDGIDATQHMADRFPAVLPVGEVLAIVTA 120 ++AA L HPHI+ VHDRGEF+GQLWI+MDY++G DA + ++PA +PV EV+A+VTA Sbjct 61 ADLAATLLHPHIVGVHDRGEFNGQLWISMDYIEGTDAAALIRSQYPAGMPVAEVVAVVTA 120 Query 121 VAGALDYAHQRGLLHRDVNPANVVLTS-QSAGDQRILLADFGIASQ-------------- 165 VAGALDYAHQRGLLHRDV PAN++LT +AG RI LADFGIA Q Sbjct 121 VAGALDYAHQRGLLHRDVKPANILLTGPDNAGGPRIFLADFGIARQLDDISGITATNLTV 180 Query 166 --PSYPAPELSAGADVDGRADQYALALTAIHLFAGAPPVDRSH---------TGPLQPPK 214 +Y APE GADVDGRADQYALA TA HL GAPP ++ T P PP Sbjct 181 GTAAYAAPEQLTGADVDGRADQYALAATAFHLLTGAPPYQHANSVAVISQHLTAP--PPA 238 Query 215 LSAFRPDLARLDGVLSRALATAPADRFGSCREFADAMNEQA 255 L R +LA LD V + ALA P +R+ C +FA A+++ A Sbjct 239 LGDRRSELAPLDRVFAAALAKQPNERYWRCADFAQALSQVA 279 >gi|240172797|ref|ZP_04751456.1| serine/threonine-protein kinase PknF_2 [Mycobacterium kansasii ATCC 12478] Length=514 Score = 256 bits (655), Expect = 5e-66, Method: Compositional matrix adjust. Identities = 137/270 (51%), Positives = 172/270 (64%), Gaps = 28/270 (10%) Query 1 MALASGVTFAGYTVVRMLGCSAMGEVYLVQHPGFPGWQALKVLSPAMAADDEFRRRFQRE 60 + L G FAGYT+VR+LG MGEVYL QHP P +ALK+L ++ADD+FRRRF RE Sbjct 15 IGLKVGDIFAGYTIVRLLGAGGMGEVYLAQHPRLPRREALKILGGEVSADDDFRRRFIRE 74 Query 61 TEVAARLFHPHILEVHDRGEFDGQLWIAMDYVDGIDATQHMADRFPAVLPVGEVLAIVTA 120 +VA+ L+HP+I+ V+DRGEFDG+LWI+MD+VDG DA + +RFPA +P +V+ I+ A Sbjct 75 ADVASALWHPNIVRVNDRGEFDGKLWISMDFVDGTDAASLLRNRFPAGMPADQVVTIIAA 134 Query 121 VAGALDYAHQ-RGLLHRDVNPANVVLTSQSAGDQRILLADFGIASQPS------------ 167 +A ALD+AHQ ++HRDV+PAN++L GDQRILL DFGIA Sbjct 135 IASALDHAHQHHNVMHRDVSPANILLADPDGGDQRILLGDFGIARSIGETSGLTATNMTI 194 Query 168 ----YPAPELSAGADVDGRADQYALALTAIHLFAG---------APPVDRSHTGPLQPPK 214 Y APE GA++DGRADQYALA TA HL AG A + R T P PP Sbjct 195 GTFPYAAPEQLTGAEIDGRADQYALAATAYHLLAGSTLFPHTNPAVVISRHLTTP--PPA 252 Query 215 LSAFRPDLARLDGVLSRALATAPADRFGSC 244 L+ P A D VL+ ALA PADRF C Sbjct 253 LAQIHPPFAAFDPVLAVALAKDPADRFACC 282 >gi|289750305|ref|ZP_06509683.1| serine/threonine protein kinase [Mycobacterium tuberculosis T92] gi|289690892|gb|EFD58321.1| serine/threonine protein kinase [Mycobacterium tuberculosis T92] Length=268 Score = 255 bits (652), Expect = 1e-65, Method: Compositional matrix adjust. Identities = 137/269 (51%), Positives = 167/269 (63%), Gaps = 27/269 (10%) Query 1 MALASGVTFAGYTVVRMLGCSAMGEVYLVQHPGFPGWQALKVLSPAMAADDEFRRRFQRE 60 M LA G TFAG+T+VR LG MGEVYL +HP P ALKVL ++AD E+R RF RE Sbjct 1 MPLAEGSTFAGFTIVRQLGSGGMGEVYLARHPRLPRQDALKVLRADVSADGEYRARFNRE 60 Query 61 TEVAARLFHPHILEVHDRGEFDGQLWIAMDYVDGIDATQHMADRFPAVLPVGEVLAIVTA 120 + AA L+HPHI+ VHDRGEFDGQLWI MD+VDG D + DR+P +P EV I+TA Sbjct 61 ADAAASLWHPHIVAVHDRGEFDGQLWIDMDFVDGTDTVSLLRDRYPNGMPGPEVTEIITA 120 Query 121 VAGALDYAHQRGLLHRDVNPANVVLTSQSAGDQRILLADFGIA----------------S 164 VA ALDYAH+R LLHRDV PAN+++ + + D+RI+LADFGIA Sbjct 121 VAEALDYAHERRLLHRDVKPANILIANPDSPDRRIMLADFGIAGWVDDPSGLTATNMTVG 180 Query 165 QPSYPAPELSAGADVDGRADQYALALTAIHLFAGAPPVDRSHTGP---------LQPPKL 215 SY APE G ++DGRADQYALA TA HL G+PP H P PP + Sbjct 181 TVSYAAPEQLMGNELDGRADQYALAATAFHLLTGSPPF--QHANPAVVISQHLSASPPAI 238 Query 216 SAFRPDLARLDGVLSRALATAPADRFGSC 244 P+L LD V ++ALA P DR+ C Sbjct 239 GDRVPELTPLDPVFAKALAKQPKDRYQRC 267 >gi|240173245|ref|ZP_04751903.1| anchored-membrane serine/threonine-protein kinase [Mycobacterium kansasii ATCC 12478] Length=630 Score = 254 bits (650), Expect = 2e-65, Method: Compositional matrix adjust. Identities = 135/291 (47%), Positives = 173/291 (60%), Gaps = 23/291 (7%) Query 1 MALASGVTFAGYTVVRMLGCSAMGEVYLVQHPGFPGWQALKVLSPAMAADDEFRRRFQRE 60 M LA G FAGYT++R+LG AMG VYL QHP P ALKVL + AD ++R RF RE Sbjct 1 MPLAVGEVFAGYTILRVLGAGAMGTVYLAQHPRLPRRDALKVLPAELTADPQYRARFVRE 60 Query 61 TEVAARLFHPHILEVHDRGEFDGQLWIAMDYVDGIDATQHMADRFPAVLPVGEVLAIVTA 120 E+AA L+HP+IL +HDRGE GQ WI+MD+V G DA + + DR+P +P+ I+TA Sbjct 61 AEIAASLWHPNILGIHDRGESGGQFWISMDFVAGTDAAKLLRDRYPRGMPLELAAPIITA 120 Query 121 VAGALDYAHQRGLLHRDVNPANVVLTSQSAGDQRILLADFGIA----------------S 164 V ALDYAHQRGLLHRDV PAN+++ + QR+ LADFGIA Sbjct 121 VGSALDYAHQRGLLHRDVKPANILIADPGSETQRVFLADFGIARPVDDTAGLTATNFAIG 180 Query 165 QPSYPAPELSAGADVDGRADQYALALTAIHLFAGAPPVDRSHTGPL-------QPPKLSA 217 +Y APE G +DGRADQYALA TA H+ +G P + + PP + Sbjct 181 TVAYAAPEQLMGEPIDGRADQYALACTAFHMLSGTQPYESPSAAAVITKHVMAPPPPIGE 240 Query 218 FRPDLARLDGVLSRALATAPADRFGSCREFADAMNEQAGVAIADQSSGGVD 268 RP+LARLD V +RA+A PA+RF CR+F + + +A G D Sbjct 241 RRPELARLDPVFARAMAKKPAERFAHCRDFTEQLAPGCAPTLAGSGPSGQD 291 >gi|240172043|ref|ZP_04750702.1| anchored-membrane serine/threonine-protein kinase [Mycobacterium kansasii ATCC 12478] Length=607 Score = 254 bits (648), Expect = 4e-65, Method: Compositional matrix adjust. Identities = 134/277 (49%), Positives = 168/277 (61%), Gaps = 23/277 (8%) Query 1 MALASGVTFAGYTVVRMLGCSAMGEVYLVQHPGFPGWQALKVLSPAMAADDEFRRRFQRE 60 MAL G FAGYT++R+LG MG VYL HP P ALKVL + D ++R RF RE Sbjct 1 MALEVGQVFAGYTILRVLGAGGMGHVYLAAHPRLPREDALKVLPAELTDDPQYRARFMRE 60 Query 61 TEVAARLFHPHILEVHDRGEFDGQLWIAMDYVDGIDATQHMADRFPAVLPVGEVLAIVTA 120 E+AA L HPHI+ +HDRGE+ LWI+M+YV G DA + + + PA +PV E L+I+TA Sbjct 61 AELAAVLSHPHIVGIHDRGEYHSHLWISMEYVAGTDAGRLLREHCPAGMPVDEALSIITA 120 Query 121 VAGALDYAHQRGLLHRDVNPANVVLTSQSAGDQRILLADFGIASQ--------------- 165 VA ALDYAH RGLLHRDV PAN++LT G R+ LADFGIA + Sbjct 121 VASALDYAHHRGLLHRDVKPANILLTGPDGGPGRVFLADFGIARRIDDAAGLTRTNMAVG 180 Query 166 -PSYPAPELSAGADVDGRADQYALALTAIHLFAGAPPVDRSHTGPL-------QPPKLSA 217 +Y +PE G +DGRADQY+LA TA L GAPP S+ + PP + A Sbjct 181 TVAYASPEQLMGKPIDGRADQYSLACTAFQLLTGAPPYGGSNLAVVIGQHVSAAPPSIGA 240 Query 218 FRPDLARLDGVLSRALATAPADRFGSCREFADAMNEQ 254 + P+L LD V + ALA PA RF SC EFAD ++ Sbjct 241 YHPELTGLDPVFTTALAKEPAKRFSSCGEFADQLSRH 277 >gi|126433399|ref|YP_001069090.1| protein kinase [Mycobacterium sp. JLS] gi|126233199|gb|ABN96599.1| protein kinase [Mycobacterium sp. JLS] Length=621 Score = 253 bits (647), Expect = 5e-65, Method: Compositional matrix adjust. Identities = 130/276 (48%), Positives = 168/276 (61%), Gaps = 25/276 (9%) Query 1 MALASGVTFAGYTVVRMLGCSAMGEVYLVQHPGFPGWQALKVLSPAMAADDEFRRRFQRE 60 M L G AGYT+ RMLG MGEVYL QHP P ALKVL +++AD +F RF RE Sbjct 1 MPLGDGTKIAGYTIRRMLGSGGMGEVYLAQHPRLPREDALKVLKSSISADPDFVERFNRE 60 Query 61 TEVAARLFHPHILEVHDRGEFDGQLWIAMDYVDGIDATQHMADRFPAVLPVGEVLAIVTA 120 ++AA+L+HPHI+ +HDRG + G+LWI+MD+VDG D + + ++P +P + L IV A Sbjct 61 ADLAAKLWHPHIVGIHDRGRYRGRLWISMDFVDGTDVGRLLQQKYPDGMPADDALEIVEA 120 Query 121 VAGALDYAHQRGLLHRDVNPANVVLTSQSAGDQRILLADFGIASQ--------------- 165 VA ALDYAH RGLLHRDV PAN+++ ++RILL DFG+A Sbjct 121 VASALDYAHSRGLLHRDVKPANILIADVENDERRILLGDFGVARDLADDAGGGLTQTNMT 180 Query 166 ---PSYPAPELSAGADVDGRADQYALALTAIHLFAGAPPVDRSHTGPLQ-------PPKL 215 +Y APE G DVDGR DQY+LA+TA H+ GAPP S + PP L Sbjct 181 VGTAAYAAPEQLMGLDVDGRTDQYSLAVTAFHMLTGAPPFQNSRPTVVVGQHLNTPPPLL 240 Query 216 SAFRPDLARLDGVLSRALATAPADRFGSCREFADAM 251 + P+LA LD + RALA P +RF +C EFA A+ Sbjct 241 ADTHPELAPLDAAMQRALAKNPDERFDTCTEFARAL 276 >gi|108797772|ref|YP_637969.1| serine/threonine protein kinase [Mycobacterium sp. MCS] gi|119866863|ref|YP_936815.1| protein kinase [Mycobacterium sp. KMS] gi|108768191|gb|ABG06913.1| serine/threonine protein kinase [Mycobacterium sp. MCS] gi|119692952|gb|ABL90025.1| protein kinase [Mycobacterium sp. KMS] Length=623 Score = 253 bits (647), Expect = 6e-65, Method: Compositional matrix adjust. Identities = 130/276 (48%), Positives = 168/276 (61%), Gaps = 25/276 (9%) Query 1 MALASGVTFAGYTVVRMLGCSAMGEVYLVQHPGFPGWQALKVLSPAMAADDEFRRRFQRE 60 M L G AGYT+ RMLG MGEVYL QHP P ALKVL +++AD +F RF RE Sbjct 1 MPLGDGTKIAGYTIRRMLGSGGMGEVYLAQHPRLPREDALKVLKSSISADPDFVERFNRE 60 Query 61 TEVAARLFHPHILEVHDRGEFDGQLWIAMDYVDGIDATQHMADRFPAVLPVGEVLAIVTA 120 ++AA+L+HPHI+ +HDRG + G+LWI+MD+VDG D + + ++P +P + L IV A Sbjct 61 ADLAAKLWHPHIVGIHDRGRYRGRLWISMDFVDGTDVGRLLQQKYPDGMPADDALEIVEA 120 Query 121 VAGALDYAHQRGLLHRDVNPANVVLTSQSAGDQRILLADFGIASQ--------------- 165 VA ALDYAH RGLLHRDV PAN+++ ++RILL DFG+A Sbjct 121 VASALDYAHSRGLLHRDVKPANILIADVENDERRILLGDFGVARDLADDAGGGLTQTNMT 180 Query 166 ---PSYPAPELSAGADVDGRADQYALALTAIHLFAGAPPVDRSHTGPLQ-------PPKL 215 +Y APE G DVDGR DQY+LA+TA H+ GAPP S + PP L Sbjct 181 VGTAAYAAPEQLMGLDVDGRTDQYSLAVTAFHMLTGAPPFQNSRPTVVVGQHLNTPPPLL 240 Query 216 SAFRPDLARLDGVLSRALATAPADRFGSCREFADAM 251 + P+LA LD + RALA P +RF +C EFA A+ Sbjct 241 ADTHPELAPLDAAMQRALAKNPDERFDTCTEFARAL 276 >gi|240168646|ref|ZP_04747305.1| membrane-anchored serine/threonine-protein kinase [Mycobacterium kansasii ATCC 12478] Length=595 Score = 253 bits (647), Expect = 6e-65, Method: Compositional matrix adjust. Identities = 135/277 (49%), Positives = 173/277 (63%), Gaps = 23/277 (8%) Query 1 MALASGVTFAGYTVVRMLGCSAMGEVYLVQHPGFPGWQALKVLSPAMAADDEFRRRFQRE 60 M +G FAGY + R+LG MGEVYL QHP P ALKVLS A AD EF+ RF+RE Sbjct 1 MPFDNGEVFAGYVIQRLLGTGGMGEVYLAQHPRLPRHDALKVLSLAATADQEFQARFKRE 60 Query 61 TEVAARLFHPHILEVHDRGEFDGQLWIAMDYVDGIDATQHMADRFPAVLPVGEVLAIVTA 120 E+AA L+HPHI+ V DRGEF+G+LWI+M+YVDG DA + + +R+P +P +V IVTA Sbjct 61 AELAATLWHPHIVGVLDRGEFNGRLWISMEYVDGTDAGRLVRERYPHGMPEQDVAEIVTA 120 Query 121 VAGALDYAHQRGLLHRDVNPANVVLTSQSAGDQRILLADFGIASQ--------------- 165 VA ALD+ H R LLHRDV P N+++T+ +R+LL DFGIA + Sbjct 121 VADALDFGHDRRLLHRDVKPENILVTAPDGHRRRVLLTDFGIARRIDDVSNLTDVNVAIG 180 Query 166 -PSYPAPELSAGADVDGRADQYALALTAIHLFAGAPPVDRSHTGPLQ-------PPKLSA 217 SY APE G +DGRADQYALA T +L GAPP S+ + PP++S Sbjct 181 TISYVAPEQLLGKPLDGRADQYALAATTFYLLTGAPPFQDSNRAVVVSNHLNTPPPRISE 240 Query 218 FRPDLARLDGVLSRALATAPADRFGSCREFADAMNEQ 254 RP+LA LD VL+RALA P R+ +C FA A+ + Sbjct 241 RRPELAHLDAVLARALAKDPNQRYPTCTAFALALTQH 277 >gi|169245915|gb|ACA50936.1| transmembrane serine/threonine-protein kinase [Mycobacterium marinum DL240490] Length=624 Score = 253 bits (645), Expect = 1e-64, Method: Compositional matrix adjust. Identities = 136/275 (50%), Positives = 175/275 (64%), Gaps = 25/275 (9%) Query 1 MALASGVTFAGYTVVRMLGCSAMGEVYLVQHPGFPGWQALKVLSPAMAADDEFRRRFQRE 60 M+LA G TFA YT+VR+LG MGEVYL QHP P ALKV+ +++A+ FR RF RE Sbjct 8 MSLAVGETFAAYTIVRLLGSGGMGEVYLAQHPRLPRRDALKVMDRSVSAEPGFRERFLRE 67 Query 61 TEVAARLFHPHILEVHDRGEFDGQLWIAMDYVDGIDATQHMADRFPAVLPVGEVLAIVTA 120 ++A+ L+HPHI+ VHDRGE+ GQLWI+MD+VDG D + + R+PA +P +A+V A Sbjct 68 ADLASALWHPHIVGVHDRGEYRGQLWISMDFVDGEDCGRLIERRYPAGMPQEMAIAVVEA 127 Query 121 VAGALDYAHQRGLLHRDVNPANVVLTSQSAGDQ-RILLADFGIASQPS------------ 167 VA ALDYAH +GLLHRDV PAN++L + +Q R+LL DFGIA + + Sbjct 128 VASALDYAHNQGLLHRDVKPANIMLANIDDHEQRRVLLTDFGIARECNDISGLTTTNMAV 187 Query 168 ----YPAPELSAGADVDGRADQYALALTAIHLFAGA-------PPVDRSHTGPLQPPKLS 216 Y APE GADVD RADQYALA TA HL +G P V SH PP+L+ Sbjct 188 GTVAYCAPEQLMGADVDSRADQYALAATAYHLLSGMTLFPHLNPAVVISHHLNADPPRLA 247 Query 217 AFRPDLARLDGVLSRALATAPADRFGSCREFADAM 251 R +L LD L++ALA P DR+ C +FA A+ Sbjct 248 EVRAEL-ELDQALAKALAKNPHDRYARCADFAHAL 281 >gi|315446500|ref|YP_004079379.1| serine/threonine protein kinase [Mycobacterium sp. Spyr1] gi|315264803|gb|ADU01545.1| serine/threonine protein kinase [Mycobacterium sp. Spyr1] Length=451 Score = 250 bits (638), Expect = 6e-64, Method: Compositional matrix adjust. Identities = 157/378 (42%), Positives = 208/378 (56%), Gaps = 79/378 (20%) Query 1 MALASGVTFAGYTVVRMLGCSAMGEVYLVQHPGFPGWQALKVLSPAMAADDEFRRRFQRE 60 M L++G +GYT+ RMLG MGEVYL +HP P + ALKVLS +++ D E+R RF RE Sbjct 1 MPLSAGEVISGYTISRMLGAGGMGEVYLAKHPRLPRYDALKVLSASVSTDSEYRERFNRE 60 Query 61 TEVAARLFHPHILEVHDRGEFDGQLWIAMDYVDGIDATQHMADRFPAVLPVGEVLAIVTA 120 ++AA L+HPHI++VHDRGEF+G+LWI+MD+V+G DA + +A+R+P +P V +VTA Sbjct 61 ADIAASLWHPHIVQVHDRGEFEGRLWISMDHVEGTDAARLLAERYPDGMPPALVARLVTA 120 Query 121 VAGALDYAHQRGLLHRDVNPANVVLTSQSAGDQRILLADFGIASQP-------------- 166 V ALDYAHQRGLLHRDV PAN+++ ++RI+LADFGIA + Sbjct 121 VGEALDYAHQRGLLHRDVKPANILIADPETENERIMLADFGIARRVGEVSALTGTNMTVG 180 Query 167 --SYPAPE-LSAGADVDGRADQYALALTAIHLFAGAPPVDRSHTGPL-------QPPKLS 216 +Y APE L+A +DGRADQYALA TA L G P S+ + QPP ++ Sbjct 181 TVAYSAPEQLTADEAIDGRADQYALAATAFQLLTGKAPFQHSNPAIVISQHLTAQPPSIA 240 Query 217 AFRPDLARLDGVLSRALATAPADRFGSCREFADAMNEQAGVAIADQSSGGVDASEVTAAA 276 RP+L+ L +ALA +PADR+ C +FA A++ + S VTAA Sbjct 241 VHRPELSGLGAAFQKALAKSPADRYDRCVDFARALSNR---------------STVTAAG 285 Query 277 GEEAYVVDYPAYGWPEAVDCKEPSARAPAPAAPTPQRRGSMLQSAAGVLARRLDNFSTAT 336 +P A A APA PT R A Sbjct 286 ---------------------DPDATAHAPATPTGPRHAK----------------PAAP 308 Query 337 KAPASPTRRRPRRILVGA 354 A AS +R R ILVGA Sbjct 309 TAQASASRGR---ILVGA 323 >gi|145221764|ref|YP_001132442.1| protein kinase [Mycobacterium gilvum PYR-GCK] gi|145214250|gb|ABP43654.1| protein kinase [Mycobacterium gilvum PYR-GCK] Length=451 Score = 250 bits (638), Expect = 6e-64, Method: Compositional matrix adjust. Identities = 157/378 (42%), Positives = 208/378 (56%), Gaps = 79/378 (20%) Query 1 MALASGVTFAGYTVVRMLGCSAMGEVYLVQHPGFPGWQALKVLSPAMAADDEFRRRFQRE 60 M L++G +GYT+ RMLG MGEVYL +HP P + ALKVLS +++ D E+R RF RE Sbjct 1 MPLSAGEVISGYTISRMLGAGGMGEVYLAKHPRLPRYDALKVLSASVSTDSEYRERFNRE 60 Query 61 TEVAARLFHPHILEVHDRGEFDGQLWIAMDYVDGIDATQHMADRFPAVLPVGEVLAIVTA 120 ++AA L+HPHI++VHDRGEF+G+LWI+MD+V+G DA + +A+R+P +P V +VTA Sbjct 61 ADIAASLWHPHIVQVHDRGEFEGRLWISMDHVEGTDAARLLAERYPDGMPPALVARLVTA 120 Query 121 VAGALDYAHQRGLLHRDVNPANVVLTSQSAGDQRILLADFGIASQP-------------- 166 V ALDYAHQRGLLHRDV PAN+++ ++RI+LADFGIA + Sbjct 121 VGEALDYAHQRGLLHRDVKPANILIADPETENERIMLADFGIARRVGEVSALTGTNMTVG 180 Query 167 --SYPAPE-LSAGADVDGRADQYALALTAIHLFAGAPPVDRSHTGPL-------QPPKLS 216 +Y APE L+A +DGRADQYALA TA L G P S+ + QPP ++ Sbjct 181 TVAYSAPEQLTADEAIDGRADQYALAATAFQLLTGKAPFQHSNPAIVISQHLTAQPPSIA 240 Query 217 AFRPDLARLDGVLSRALATAPADRFGSCREFADAMNEQAGVAIADQSSGGVDASEVTAAA 276 RP+L+ L +ALA +PADR+ C +FA A++ + S VTAA Sbjct 241 VHRPELSGLGAAFQKALAKSPADRYDRCVDFARALSNR---------------STVTAAG 285 Query 277 GEEAYVVDYPAYGWPEAVDCKEPSARAPAPAAPTPQRRGSMLQSAAGVLARRLDNFSTAT 336 +P A A APA PT R A Sbjct 286 ---------------------DPDATAHAPATPTGPRHAK----------------PAAP 308 Query 337 KAPASPTRRRPRRILVGA 354 A AS +R R ILVGA Sbjct 309 TAQASASRGR---ILVGA 323 Lambda K H 0.317 0.132 0.399 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 1325094442320 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40