BLASTP 2.2.25+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.



Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
           15,229,318 sequences; 5,219,829,388 total letters



Query= Rv2924c

Length=289
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

gi|15610061|ref|NP_217440.1|  formamidopyrimidine-DNA glycosylase...   585    2e-165
gi|306777215|ref|ZP_07415552.1|  formamidopyrimidine-DNA glycosyl...   584    4e-165
gi|339295763|gb|AEJ47874.1|  formamidopyrimidine-DNA glycosylase ...   584    6e-165
gi|253797987|ref|YP_003030988.1|  formamidopyrimidine-DNA glycosy...   584    6e-165
gi|328457761|gb|AEB03184.1|  formamidopyrimidine-DNA glycosylase ...   582    2e-164
gi|294993978|ref|ZP_06799669.1|  formamidopyrimidine-DNA glycosyl...   554    5e-156
gi|240169619|ref|ZP_04748278.1|  formamidopyrimidine-DNA glycosyl...   500    9e-140
gi|183981796|ref|YP_001850087.1|  formamidopyrimidine-DNA glycosy...   496    2e-138
gi|342858222|ref|ZP_08714877.1|  formamidopyrimidine/5-formylurac...   496    2e-138
gi|296171391|ref|ZP_06852724.1|  DNA-formamidopyrimidine glycosyl...   494    9e-138
gi|118617607|ref|YP_905939.1|  formamidopyrimidine-DNA glycosylas...   491    4e-137
gi|118464268|ref|YP_882954.1|  formamidopyrimidine-DNA glycosylas...   488    3e-136
gi|41409092|ref|NP_961928.1|  formamidopyrimidine-DNA glycosylase...   486    2e-135
gi|254822110|ref|ZP_05227111.1|  formamidopyrimidine-DNA glycosyl...   484    8e-135
gi|126434518|ref|YP_001070209.1|  formamidopyrimidine-DNA glycosy...   466    2e-129
gi|108798918|ref|YP_639115.1|  formamidopyrimidine-DNA glycosylas...   462    3e-128
gi|120403164|ref|YP_952993.1|  formamidopyrimidine-DNA glycosylas...   462    3e-128
gi|15827876|ref|NP_302139.1|  formamidopyrimidine-DNA glycosylase...   452    2e-125
gi|145224770|ref|YP_001135448.1|  formamidopyrimidine-DNA glycosy...   447    1e-123
gi|118470267|ref|YP_886759.1|  formamidopyrimidine-DNA glycosylas...   443    1e-122
gi|333991296|ref|YP_004523910.1|  formamidopyrimidine-DNA glycosy...   425    4e-117
gi|325675925|ref|ZP_08155608.1|  DNA-formamidopyrimidine glycosyl...   381    7e-104
gi|226365984|ref|YP_002783767.1|  formamidopyrimidine-DNA glycosy...   374    1e-101
gi|111023482|ref|YP_706454.1|  formamidopyrimidine-DNA glycosylas...   372    4e-101
gi|169630336|ref|YP_001703985.1|  formamidopyrimidine-DNA glycosy...   371    9e-101
gi|229491415|ref|ZP_04385239.1|  formamidopyrimidine-DNA glycosyl...   358    7e-97 
gi|296139285|ref|YP_003646528.1|  formamidopyrimidine-DNA glycosy...   357    1e-96 
gi|226305919|ref|YP_002765879.1|  formamidopyrimidine-DNA glycosy...   357    2e-96 
gi|54026154|ref|YP_120396.1|  formamidopyrimidine-DNA glycosylase...   352    4e-95 
gi|343925328|ref|ZP_08764853.1|  formamidopyrimidine-DNA glycosyl...   344    8e-93 
gi|262202010|ref|YP_003273218.1|  formamidopyrimidine-DNA glycosy...   339    2e-91 
gi|333920820|ref|YP_004494401.1|  fomramidopyrimidine-DNA glycosy...   336    3e-90 
gi|300783720|ref|YP_003764011.1|  formamidopyrimidine-DNA glycosy...   333    2e-89 
gi|256379956|ref|YP_003103616.1|  formamidopyrimidine-DNA glycosy...   327    1e-87 
gi|302525052|ref|ZP_07277394.1|  formamidopyrimidine-DNA glycosyl...   327    2e-87 
gi|331698523|ref|YP_004334762.1|  formamidopyrimidine-DNA glycosy...   321    7e-86 
gi|134102536|ref|YP_001108197.1|  formamidopyrimidine-DNA glycosy...   320    2e-85 
gi|257055002|ref|YP_003132834.1|  formamidopyrimidine-DNA glycosy...   320    2e-85 
gi|296393288|ref|YP_003658172.1|  formamidopyrimidine-DNA glycosy...   317    2e-84 
gi|345009586|ref|YP_004811940.1|  Formamidopyrimidine-DNA glycosy...   316    3e-84 
gi|326382853|ref|ZP_08204543.1|  formamidopyrimidine/5-formylurac...   315    4e-84 
gi|294815351|ref|ZP_06773994.1|  DNA glycosylase [Streptomyces cl...   315    5e-84 
gi|239991060|ref|ZP_04711724.1|  formamidopyrimidine-DNA glycosyl...   315    5e-84 
gi|311742942|ref|ZP_07716750.1|  DNA-formamidopyrimidine glycosyl...   312    3e-83 
gi|182435700|ref|YP_001823419.1|  formamidopyrimidine-DNA glycosy...   311    6e-83 
gi|326776325|ref|ZP_08235590.1|  Formamidopyrimidine-DNA glycosyl...   311    8e-83 
gi|302554408|ref|ZP_07306750.1|  formamidopyrimidine-DNA glycosyl...   307    1e-81 
gi|21223929|ref|NP_629708.1|  formamidopyrimidine-DNA glycosylase...   307    1e-81 
gi|254392459|ref|ZP_05007639.1|  formamidopyrimidine-DNA glycosyl...   307    1e-81 
gi|329936741|ref|ZP_08286448.1|  formamidopyrimidine-DNA glycosyl...   306    2e-81 


>gi|15610061|ref|NP_217440.1| formamidopyrimidine-DNA glycosylase [Mycobacterium tuberculosis 
H37Rv]
 gi|15842470|ref|NP_337507.1| formamidopyrimidine-DNA glycosylase [Mycobacterium tuberculosis 
CDC1551]
 gi|31794101|ref|NP_856594.1| formamidopyrimidine-DNA glycosylase [Mycobacterium bovis AF2122/97]
 66 more sequence titles
 Length=289

 Score =  585 bits (1509),  Expect = 2e-165, Method: Compositional matrix adjust.
 Identities = 289/289 (100%), Positives = 289/289 (100%), Gaps = 0/289 (0%)

Query  1    MPELPEVEVVRRGLQAHVTGRTITEVRVHHPRAVRRHDAGPADLTARLRGARINGTDRRG  60
            MPELPEVEVVRRGLQAHVTGRTITEVRVHHPRAVRRHDAGPADLTARLRGARINGTDRRG
Sbjct  1    MPELPEVEVVRRGLQAHVTGRTITEVRVHHPRAVRRHDAGPADLTARLRGARINGTDRRG  60

Query  61   KYLWLTLNTAGVHRPTDTALVVHLGMSGQMLLGAVPCAAHVRISALLDDGTVLSFADQRT  120
            KYLWLTLNTAGVHRPTDTALVVHLGMSGQMLLGAVPCAAHVRISALLDDGTVLSFADQRT
Sbjct  61   KYLWLTLNTAGVHRPTDTALVVHLGMSGQMLLGAVPCAAHVRISALLDDGTVLSFADQRT  120

Query  121  FGGWLLADLVTVDGSVVPVPVAHLARDPLDPRFDCDAVVKVLRRKHSELKRQLLDQRVVS  180
            FGGWLLADLVTVDGSVVPVPVAHLARDPLDPRFDCDAVVKVLRRKHSELKRQLLDQRVVS
Sbjct  121  FGGWLLADLVTVDGSVVPVPVAHLARDPLDPRFDCDAVVKVLRRKHSELKRQLLDQRVVS  180

Query  181  GIGNIYADEALWRAKVNGAHVAATLRCRRLGAVLHAAADVMREALAKGGTSFDSLYVNVN  240
            GIGNIYADEALWRAKVNGAHVAATLRCRRLGAVLHAAADVMREALAKGGTSFDSLYVNVN
Sbjct  181  GIGNIYADEALWRAKVNGAHVAATLRCRRLGAVLHAAADVMREALAKGGTSFDSLYVNVN  240

Query  241  GESGYFERSLDAYGREGENCRRCGAVIRRERFMNRSSFYCPRCQPRPRK  289
            GESGYFERSLDAYGREGENCRRCGAVIRRERFMNRSSFYCPRCQPRPRK
Sbjct  241  GESGYFERSLDAYGREGENCRRCGAVIRRERFMNRSSFYCPRCQPRPRK  289


>gi|306777215|ref|ZP_07415552.1| formamidopyrimidine-DNA glycosylase fpg [Mycobacterium tuberculosis 
SUMu001]
 gi|306973332|ref|ZP_07485993.1| formamidopyrimidine-DNA glycosylase fpg [Mycobacterium tuberculosis 
SUMu010]
 gi|307081038|ref|ZP_07490208.1| formamidopyrimidine-DNA glycosylase fpg [Mycobacterium tuberculosis 
SUMu011]
 gi|308214424|gb|EFO73823.1| formamidopyrimidine-DNA glycosylase fpg [Mycobacterium tuberculosis 
SUMu001]
 gi|308357235|gb|EFP46086.1| formamidopyrimidine-DNA glycosylase fpg [Mycobacterium tuberculosis 
SUMu010]
 gi|308361244|gb|EFP50095.1| formamidopyrimidine-DNA glycosylase fpg [Mycobacterium tuberculosis 
SUMu011]
Length=289

 Score =  584 bits (1506),  Expect = 4e-165, Method: Compositional matrix adjust.
 Identities = 288/289 (99%), Positives = 289/289 (100%), Gaps = 0/289 (0%)

Query  1    MPELPEVEVVRRGLQAHVTGRTITEVRVHHPRAVRRHDAGPADLTARLRGARINGTDRRG  60
            MPELPEVEVVRRGLQAH+TGRTITEVRVHHPRAVRRHDAGPADLTARLRGARINGTDRRG
Sbjct  1    MPELPEVEVVRRGLQAHMTGRTITEVRVHHPRAVRRHDAGPADLTARLRGARINGTDRRG  60

Query  61   KYLWLTLNTAGVHRPTDTALVVHLGMSGQMLLGAVPCAAHVRISALLDDGTVLSFADQRT  120
            KYLWLTLNTAGVHRPTDTALVVHLGMSGQMLLGAVPCAAHVRISALLDDGTVLSFADQRT
Sbjct  61   KYLWLTLNTAGVHRPTDTALVVHLGMSGQMLLGAVPCAAHVRISALLDDGTVLSFADQRT  120

Query  121  FGGWLLADLVTVDGSVVPVPVAHLARDPLDPRFDCDAVVKVLRRKHSELKRQLLDQRVVS  180
            FGGWLLADLVTVDGSVVPVPVAHLARDPLDPRFDCDAVVKVLRRKHSELKRQLLDQRVVS
Sbjct  121  FGGWLLADLVTVDGSVVPVPVAHLARDPLDPRFDCDAVVKVLRRKHSELKRQLLDQRVVS  180

Query  181  GIGNIYADEALWRAKVNGAHVAATLRCRRLGAVLHAAADVMREALAKGGTSFDSLYVNVN  240
            GIGNIYADEALWRAKVNGAHVAATLRCRRLGAVLHAAADVMREALAKGGTSFDSLYVNVN
Sbjct  181  GIGNIYADEALWRAKVNGAHVAATLRCRRLGAVLHAAADVMREALAKGGTSFDSLYVNVN  240

Query  241  GESGYFERSLDAYGREGENCRRCGAVIRRERFMNRSSFYCPRCQPRPRK  289
            GESGYFERSLDAYGREGENCRRCGAVIRRERFMNRSSFYCPRCQPRPRK
Sbjct  241  GESGYFERSLDAYGREGENCRRCGAVIRRERFMNRSSFYCPRCQPRPRK  289


>gi|339295763|gb|AEJ47874.1| formamidopyrimidine-DNA glycosylase fpg [Mycobacterium tuberculosis 
CCDC5079]
 gi|339299376|gb|AEJ51486.1| formamidopyrimidine-DNA glycosylase fpg [Mycobacterium tuberculosis 
CCDC5180]
Length=306

 Score =  584 bits (1505),  Expect = 6e-165, Method: Compositional matrix adjust.
 Identities = 289/289 (100%), Positives = 289/289 (100%), Gaps = 0/289 (0%)

Query  1    MPELPEVEVVRRGLQAHVTGRTITEVRVHHPRAVRRHDAGPADLTARLRGARINGTDRRG  60
            MPELPEVEVVRRGLQAHVTGRTITEVRVHHPRAVRRHDAGPADLTARLRGARINGTDRRG
Sbjct  18   MPELPEVEVVRRGLQAHVTGRTITEVRVHHPRAVRRHDAGPADLTARLRGARINGTDRRG  77

Query  61   KYLWLTLNTAGVHRPTDTALVVHLGMSGQMLLGAVPCAAHVRISALLDDGTVLSFADQRT  120
            KYLWLTLNTAGVHRPTDTALVVHLGMSGQMLLGAVPCAAHVRISALLDDGTVLSFADQRT
Sbjct  78   KYLWLTLNTAGVHRPTDTALVVHLGMSGQMLLGAVPCAAHVRISALLDDGTVLSFADQRT  137

Query  121  FGGWLLADLVTVDGSVVPVPVAHLARDPLDPRFDCDAVVKVLRRKHSELKRQLLDQRVVS  180
            FGGWLLADLVTVDGSVVPVPVAHLARDPLDPRFDCDAVVKVLRRKHSELKRQLLDQRVVS
Sbjct  138  FGGWLLADLVTVDGSVVPVPVAHLARDPLDPRFDCDAVVKVLRRKHSELKRQLLDQRVVS  197

Query  181  GIGNIYADEALWRAKVNGAHVAATLRCRRLGAVLHAAADVMREALAKGGTSFDSLYVNVN  240
            GIGNIYADEALWRAKVNGAHVAATLRCRRLGAVLHAAADVMREALAKGGTSFDSLYVNVN
Sbjct  198  GIGNIYADEALWRAKVNGAHVAATLRCRRLGAVLHAAADVMREALAKGGTSFDSLYVNVN  257

Query  241  GESGYFERSLDAYGREGENCRRCGAVIRRERFMNRSSFYCPRCQPRPRK  289
            GESGYFERSLDAYGREGENCRRCGAVIRRERFMNRSSFYCPRCQPRPRK
Sbjct  258  GESGYFERSLDAYGREGENCRRCGAVIRRERFMNRSSFYCPRCQPRPRK  306


>gi|253797987|ref|YP_003030988.1| formamidopyrimidine-DNA glycosylase fpg [Mycobacterium tuberculosis 
KZN 1435]
 gi|289553286|ref|ZP_06442496.1| formamidopyrimidine-DNA glycosylase fpg [Mycobacterium tuberculosis 
KZN 605]
 gi|297635544|ref|ZP_06953324.1| formamidopyrimidine-DNA glycosylase [Mycobacterium tuberculosis 
KZN 4207]
 gi|297732543|ref|ZP_06961661.1| formamidopyrimidine-DNA glycosylase [Mycobacterium tuberculosis 
KZN R506]
 gi|313659875|ref|ZP_07816755.1| formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA 
glycosylase [Mycobacterium tuberculosis KZN V2475]
 gi|253319490|gb|ACT24093.1| formamidopyrimidine-DNA glycosylase fpg [Mycobacterium tuberculosis 
KZN 1435]
 gi|289437918|gb|EFD20411.1| formamidopyrimidine-DNA glycosylase fpg [Mycobacterium tuberculosis 
KZN 605]
Length=289

 Score =  584 bits (1505),  Expect = 6e-165, Method: Compositional matrix adjust.
 Identities = 288/289 (99%), Positives = 289/289 (100%), Gaps = 0/289 (0%)

Query  1    MPELPEVEVVRRGLQAHVTGRTITEVRVHHPRAVRRHDAGPADLTARLRGARINGTDRRG  60
            MPELPEVEVVRRGLQAHVTGRTITEVRVHHPRAVRRHDAGPADLTARLRGARINGTDRRG
Sbjct  1    MPELPEVEVVRRGLQAHVTGRTITEVRVHHPRAVRRHDAGPADLTARLRGARINGTDRRG  60

Query  61   KYLWLTLNTAGVHRPTDTALVVHLGMSGQMLLGAVPCAAHVRISALLDDGTVLSFADQRT  120
            KYLWLTLNTAGVHRPTDTALVVHLGMSGQMLLGAVPCAAHVRISALLDDGTVLSFADQRT
Sbjct  61   KYLWLTLNTAGVHRPTDTALVVHLGMSGQMLLGAVPCAAHVRISALLDDGTVLSFADQRT  120

Query  121  FGGWLLADLVTVDGSVVPVPVAHLARDPLDPRFDCDAVVKVLRRKHSELKRQLLDQRVVS  180
            FGGWLLADLVTVDGSVVPVPVAHLARDPLDPRFDCDAVVKVLRRKHSELKRQLLDQRVVS
Sbjct  121  FGGWLLADLVTVDGSVVPVPVAHLARDPLDPRFDCDAVVKVLRRKHSELKRQLLDQRVVS  180

Query  181  GIGNIYADEALWRAKVNGAHVAATLRCRRLGAVLHAAADVMREALAKGGTSFDSLYVNVN  240
            GIGNIYADEALWRAKVNGAHVAATLRCRRLGAVLHAAADVMREALAKGGTSFDSLYVNVN
Sbjct  181  GIGNIYADEALWRAKVNGAHVAATLRCRRLGAVLHAAADVMREALAKGGTSFDSLYVNVN  240

Query  241  GESGYFERSLDAYGREGENCRRCGAVIRRERFMNRSSFYCPRCQPRPRK  289
            GESGYFERSLDAYGR+GENCRRCGAVIRRERFMNRSSFYCPRCQPRPRK
Sbjct  241  GESGYFERSLDAYGRDGENCRRCGAVIRRERFMNRSSFYCPRCQPRPRK  289


>gi|328457761|gb|AEB03184.1| formamidopyrimidine-DNA glycosylase fpg [Mycobacterium tuberculosis 
KZN 4207]
Length=304

 Score =  582 bits (1501),  Expect = 2e-164, Method: Compositional matrix adjust.
 Identities = 288/289 (99%), Positives = 289/289 (100%), Gaps = 0/289 (0%)

Query  1    MPELPEVEVVRRGLQAHVTGRTITEVRVHHPRAVRRHDAGPADLTARLRGARINGTDRRG  60
            MPELPEVEVVRRGLQAHVTGRTITEVRVHHPRAVRRHDAGPADLTARLRGARINGTDRRG
Sbjct  16   MPELPEVEVVRRGLQAHVTGRTITEVRVHHPRAVRRHDAGPADLTARLRGARINGTDRRG  75

Query  61   KYLWLTLNTAGVHRPTDTALVVHLGMSGQMLLGAVPCAAHVRISALLDDGTVLSFADQRT  120
            KYLWLTLNTAGVHRPTDTALVVHLGMSGQMLLGAVPCAAHVRISALLDDGTVLSFADQRT
Sbjct  76   KYLWLTLNTAGVHRPTDTALVVHLGMSGQMLLGAVPCAAHVRISALLDDGTVLSFADQRT  135

Query  121  FGGWLLADLVTVDGSVVPVPVAHLARDPLDPRFDCDAVVKVLRRKHSELKRQLLDQRVVS  180
            FGGWLLADLVTVDGSVVPVPVAHLARDPLDPRFDCDAVVKVLRRKHSELKRQLLDQRVVS
Sbjct  136  FGGWLLADLVTVDGSVVPVPVAHLARDPLDPRFDCDAVVKVLRRKHSELKRQLLDQRVVS  195

Query  181  GIGNIYADEALWRAKVNGAHVAATLRCRRLGAVLHAAADVMREALAKGGTSFDSLYVNVN  240
            GIGNIYADEALWRAKVNGAHVAATLRCRRLGAVLHAAADVMREALAKGGTSFDSLYVNVN
Sbjct  196  GIGNIYADEALWRAKVNGAHVAATLRCRRLGAVLHAAADVMREALAKGGTSFDSLYVNVN  255

Query  241  GESGYFERSLDAYGREGENCRRCGAVIRRERFMNRSSFYCPRCQPRPRK  289
            GESGYFERSLDAYGR+GENCRRCGAVIRRERFMNRSSFYCPRCQPRPRK
Sbjct  256  GESGYFERSLDAYGRDGENCRRCGAVIRRERFMNRSSFYCPRCQPRPRK  304


>gi|294993978|ref|ZP_06799669.1| formamidopyrimidine-DNA glycosylase [Mycobacterium tuberculosis 
210]
Length=328

 Score =  554 bits (1428),  Expect = 5e-156, Method: Compositional matrix adjust.
 Identities = 276/277 (99%), Positives = 276/277 (99%), Gaps = 0/277 (0%)

Query  1    MPELPEVEVVRRGLQAHVTGRTITEVRVHHPRAVRRHDAGPADLTARLRGARINGTDRRG  60
            MPELPEVEVVRRGLQAHVTGRTITEVRVHHPRAVRRHDAGPADLTARLRGARINGTDRRG
Sbjct  16   MPELPEVEVVRRGLQAHVTGRTITEVRVHHPRAVRRHDAGPADLTARLRGARINGTDRRG  75

Query  61   KYLWLTLNTAGVHRPTDTALVVHLGMSGQMLLGAVPCAAHVRISALLDDGTVLSFADQRT  120
            KYLWLTLNTAGVHRPTDTALVVHLGMSGQMLLGAVPCAAHVRISALLDDGTVLSFADQRT
Sbjct  76   KYLWLTLNTAGVHRPTDTALVVHLGMSGQMLLGAVPCAAHVRISALLDDGTVLSFADQRT  135

Query  121  FGGWLLADLVTVDGSVVPVPVAHLARDPLDPRFDCDAVVKVLRRKHSELKRQLLDQRVVS  180
            FGGWLLADLVTVDGSVVPVPVAHLARDPLDPRFDCDAVVKVLRRKHSELKRQLLDQRVVS
Sbjct  136  FGGWLLADLVTVDGSVVPVPVAHLARDPLDPRFDCDAVVKVLRRKHSELKRQLLDQRVVS  195

Query  181  GIGNIYADEALWRAKVNGAHVAATLRCRRLGAVLHAAADVMREALAKGGTSFDSLYVNVN  240
            GIGNIYADEALWRAKVNGAHVAATLRCRRLGAVLHAAADVMREALAKGGTSFDSLYVNVN
Sbjct  196  GIGNIYADEALWRAKVNGAHVAATLRCRRLGAVLHAAADVMREALAKGGTSFDSLYVNVN  255

Query  241  GESGYFERSLDAYGREGENCRRCGAVIRRERFMNRSS  277
            GESGYFERSLDAYGREGENCRRCGAVIRRERFMNR S
Sbjct  256  GESGYFERSLDAYGREGENCRRCGAVIRRERFMNRLS  292


>gi|240169619|ref|ZP_04748278.1| formamidopyrimidine-DNA glycosylase [Mycobacterium kansasii ATCC 
12478]
Length=283

 Score =  500 bits (1288),  Expect = 9e-140, Method: Compositional matrix adjust.
 Identities = 250/289 (87%), Positives = 265/289 (92%), Gaps = 6/289 (2%)

Query  1    MPELPEVEVVRRGLQAHVTGRTITEVRVHHPRAVRRHDAGPADLTARLRGARINGTDRRG  60
            MPELPEVEVVRRGL AHV G+T+T VRVHHPRAVRRH+AGPADLTARL GARI GTDRRG
Sbjct  1    MPELPEVEVVRRGLAAHVVGKTMTAVRVHHPRAVRRHEAGPADLTARLLGARITGTDRRG  60

Query  61   KYLWLTLNTAGVHRPTDTALVVHLGMSGQMLLGAVPCAAHVRISALLDDGTVLSFADQRT  120
            KYLWLTLN+       D+ALVVHLGMSGQMLLG VP + HVRISALLDDGTVLSFADQRT
Sbjct  61   KYLWLTLNS------PDSALVVHLGMSGQMLLGVVPRSDHVRISALLDDGTVLSFADQRT  114

Query  121  FGGWLLADLVTVDGSVVPVPVAHLARDPLDPRFDCDAVVKVLRRKHSELKRQLLDQRVVS  180
            FGGWLLADLVTVDGSVVP PVAHLARDPLDPRFD  AVV+VLR KHSELKRQLL+Q VVS
Sbjct  115  FGGWLLADLVTVDGSVVPAPVAHLARDPLDPRFDARAVVEVLRGKHSELKRQLLNQEVVS  174

Query  181  GIGNIYADEALWRAKVNGAHVAATLRCRRLGAVLHAAADVMREALAKGGTSFDSLYVNVN  240
            GIGNIYADEALWRAKVNGA VAATL  R+LGAVL AAA+VMREALAKGGTSFDSLYVNVN
Sbjct  175  GIGNIYADEALWRAKVNGARVAATLTRRQLGAVLDAAAEVMREALAKGGTSFDSLYVNVN  234

Query  241  GESGYFERSLDAYGREGENCRRCGAVIRRERFMNRSSFYCPRCQPRPRK  289
            GESGYF+RSLDAYGR+G+NCRRCGAVIRRE+FMNRSSFYCPRCQPRPR+
Sbjct  235  GESGYFDRSLDAYGRDGQNCRRCGAVIRREKFMNRSSFYCPRCQPRPRR  283


>gi|183981796|ref|YP_001850087.1| formamidopyrimidine-DNA glycosylase Fpg [Mycobacterium marinum 
M]
 gi|238689243|sp|B2HJJ6.1|FPG_MYCMM RecName: Full=Formamidopyrimidine-DNA glycosylase; Short=Fapy-DNA 
glycosylase; AltName: Full=DNA-(apurinic or apyrimidinic 
site) lyase mutM; Short=AP lyase mutM
 gi|183175122|gb|ACC40232.1| formamidopyrimidine-DNA glycosylase Fpg [Mycobacterium marinum 
M]
Length=292

 Score =  496 bits (1276),  Expect = 2e-138, Method: Compositional matrix adjust.
 Identities = 249/293 (85%), Positives = 268/293 (92%), Gaps = 5/293 (1%)

Query  1    MPELPEVEVVRRGLQAHVTGRTITEVRVHHPRAVRRHDAGPADLTARLRGARINGTDRRG  60
            MPELPEVEVVRRGLQ HV G+T+T VRVHHPRAVRRH+AGPADLTARL GARI+GTDRRG
Sbjct  1    MPELPEVEVVRRGLQDHVVGKTMTAVRVHHPRAVRRHEAGPADLTARLLGARISGTDRRG  60

Query  61   KYLWLTLN----TAGVHRPTDTALVVHLGMSGQMLLGAVPCAAHVRISALLDDGTVLSFA  116
            KYLWLTL+    T G   P DTALVVHLGMSGQMLLG VP A HVRISA+LDDGTVLSFA
Sbjct  61   KYLWLTLDAGAPTTGRDDP-DTALVVHLGMSGQMLLGGVPRAEHVRISAVLDDGTVLSFA  119

Query  117  DQRTFGGWLLADLVTVDGSVVPVPVAHLARDPLDPRFDCDAVVKVLRRKHSELKRQLLDQ  176
            DQRTFGGW LADLV+VDGSVVP PVAHLARDPLDP FD D+V+KVLR KHSE+KRQLLDQ
Sbjct  120  DQRTFGGWQLADLVSVDGSVVPAPVAHLARDPLDPLFDVDSVIKVLRGKHSEIKRQLLDQ  179

Query  177  RVVSGIGNIYADEALWRAKVNGAHVAATLRCRRLGAVLHAAADVMREALAKGGTSFDSLY  236
            +VVSGIGNIYADEALWRAKV+GA VAATL  R+LGAVL AAADVMREALAKGGTSFDSLY
Sbjct  180  QVVSGIGNIYADEALWRAKVHGARVAATLTRRQLGAVLDAAADVMREALAKGGTSFDSLY  239

Query  237  VNVNGESGYFERSLDAYGREGENCRRCGAVIRRERFMNRSSFYCPRCQPRPRK  289
            VNVNG+SGYF+RSLDAYGREGE+CRRCGAV+RRE+FMNRSSFYCPRCQPRPR+
Sbjct  240  VNVNGQSGYFDRSLDAYGREGEHCRRCGAVMRREKFMNRSSFYCPRCQPRPRR  292


>gi|342858222|ref|ZP_08714877.1| formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA 
glycosylase [Mycobacterium colombiense CECT 3035]
 gi|342133926|gb|EGT87106.1| formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA 
glycosylase [Mycobacterium colombiense CECT 3035]
Length=289

 Score =  496 bits (1276),  Expect = 2e-138, Method: Compositional matrix adjust.
 Identities = 243/288 (85%), Positives = 262/288 (91%), Gaps = 0/288 (0%)

Query  1    MPELPEVEVVRRGLQAHVTGRTITEVRVHHPRAVRRHDAGPADLTARLRGARINGTDRRG  60
            MPELPEVEVVRRGL AHV G+T+T VRVHHPRAVRRH+AGPADLT RL  ARI GTDRRG
Sbjct  1    MPELPEVEVVRRGLHAHVVGKTMTAVRVHHPRAVRRHEAGPADLTVRLLNARITGTDRRG  60

Query  61   KYLWLTLNTAGVHRPTDTALVVHLGMSGQMLLGAVPCAAHVRISALLDDGTVLSFADQRT  120
            KYLWL L+T    + +DTALVVHLGMSGQMLLG VP A HVRISALLDDGTVLSFADQRT
Sbjct  61   KYLWLLLDTEPAGQESDTALVVHLGMSGQMLLGEVPRADHVRISALLDDGTVLSFADQRT  120

Query  121  FGGWLLADLVTVDGSVVPVPVAHLARDPLDPRFDCDAVVKVLRRKHSELKRQLLDQRVVS  180
            FGGW+LADLV VDGSVVP PVAHLARDPLDPRFD DAVVKVLRRKHSE+KRQLLDQ+VVS
Sbjct  121  FGGWMLADLVEVDGSVVPEPVAHLARDPLDPRFDADAVVKVLRRKHSEIKRQLLDQQVVS  180

Query  181  GIGNIYADEALWRAKVNGAHVAATLRCRRLGAVLHAAADVMREALAKGGTSFDSLYVNVN  240
            GIGNIYADEALWRAKVNGA +A TL  ++L AVL AAA+VMR+ALA+GGTSFDSLYVNVN
Sbjct  181  GIGNIYADEALWRAKVNGARIADTLSRKQLTAVLDAAAEVMRDALAQGGTSFDSLYVNVN  240

Query  241  GESGYFERSLDAYGREGENCRRCGAVIRRERFMNRSSFYCPRCQPRPR  288
            GESGYF+RSLDAYGREGE CRRCGAV+RRE+FMNRSSFYCP+CQPRPR
Sbjct  241  GESGYFDRSLDAYGREGEACRRCGAVMRREKFMNRSSFYCPKCQPRPR  288


>gi|296171391|ref|ZP_06852724.1| DNA-formamidopyrimidine glycosylase [Mycobacterium parascrofulaceum 
ATCC BAA-614]
 gi|295894166|gb|EFG73925.1| DNA-formamidopyrimidine glycosylase [Mycobacterium parascrofulaceum 
ATCC BAA-614]
Length=286

 Score =  494 bits (1271),  Expect = 9e-138, Method: Compositional matrix adjust.
 Identities = 246/289 (86%), Positives = 263/289 (92%), Gaps = 3/289 (1%)

Query  1    MPELPEVEVVRRGLQAHVTGRTITEVRVHHPRAVRRHDAGPADLTARLRGARINGTDRRG  60
            MPELPEVEVVRRGLQA V G+TIT VRVHHPRAVRRH+AGPADLTARL  ARI GTDRRG
Sbjct  1    MPELPEVEVVRRGLQAGVVGKTITAVRVHHPRAVRRHEAGPADLTARLLDARITGTDRRG  60

Query  61   KYLWLTLNTAGVHRPTDTALVVHLGMSGQMLLGAVPCAAHVRISALLDDGTVLSFADQRT  120
            KYLWL L+  G     DTALVVHLGMSGQMLLG VP A HVRISALLDDGTVLSFADQRT
Sbjct  61   KYLWLVLDGPG---QPDTALVVHLGMSGQMLLGEVPRADHVRISALLDDGTVLSFADQRT  117

Query  121  FGGWLLADLVTVDGSVVPVPVAHLARDPLDPRFDCDAVVKVLRRKHSELKRQLLDQRVVS  180
            FGGW+LADLV VDGSVVP PVAHLARDPLDPRFD DAVV VLRRKHSE+KRQLLDQ VVS
Sbjct  118  FGGWMLADLVEVDGSVVPAPVAHLARDPLDPRFDRDAVVDVLRRKHSEIKRQLLDQTVVS  177

Query  181  GIGNIYADEALWRAKVNGAHVAATLRCRRLGAVLHAAADVMREALAKGGTSFDSLYVNVN  240
            GIGNIYADEALWRAKVNGA +AATL  RRLGAVL AAA+VMR+AL++GGTSFDSLYVNVN
Sbjct  178  GIGNIYADEALWRAKVNGARIAATLSRRRLGAVLDAAAEVMRDALSQGGTSFDSLYVNVN  237

Query  241  GESGYFERSLDAYGREGENCRRCGAVIRRERFMNRSSFYCPRCQPRPRK  289
            G+SGYF+RSLDAYGREG+NCRRCGAV+RRE+FMNRSSFYCP+CQPRPR+
Sbjct  238  GQSGYFDRSLDAYGREGQNCRRCGAVMRREKFMNRSSFYCPKCQPRPRR  286


>gi|118617607|ref|YP_905939.1| formamidopyrimidine-DNA glycosylase [Mycobacterium ulcerans Agy99]
 gi|166215639|sp|A0PQ49.1|FPG_MYCUA RecName: Full=Formamidopyrimidine-DNA glycosylase; Short=Fapy-DNA 
glycosylase; AltName: Full=DNA-(apurinic or apyrimidinic 
site) lyase mutM; Short=AP lyase mutM
 gi|118569717|gb|ABL04468.1| formamidopyrimidine-DNA glycosylase Fpg [Mycobacterium ulcerans 
Agy99]
Length=292

 Score =  491 bits (1265),  Expect = 4e-137, Method: Compositional matrix adjust.
 Identities = 247/293 (85%), Positives = 267/293 (92%), Gaps = 5/293 (1%)

Query  1    MPELPEVEVVRRGLQAHVTGRTITEVRVHHPRAVRRHDAGPADLTARLRGARINGTDRRG  60
            MPELPEVEVVRRGLQ HV G+T+T VRVHHPRAVRRH+AGPADLTARL GARI+GTDRRG
Sbjct  1    MPELPEVEVVRRGLQDHVVGKTMTAVRVHHPRAVRRHEAGPADLTARLLGARISGTDRRG  60

Query  61   KYLWLTLN----TAGVHRPTDTALVVHLGMSGQMLLGAVPCAAHVRISALLDDGTVLSFA  116
            KYLWLTL+    T G   P D ALVVHLGMSGQMLLG VP A HVRISA+LDDGTVLSFA
Sbjct  61   KYLWLTLDAGAPTTGRDDP-DAALVVHLGMSGQMLLGGVPRAEHVRISAVLDDGTVLSFA  119

Query  117  DQRTFGGWLLADLVTVDGSVVPVPVAHLARDPLDPRFDCDAVVKVLRRKHSELKRQLLDQ  176
            DQRTFGGW LADLV+VDGSVVP PVAHLARDPLDP FD D+V+KVLR KHSE+KR+LLDQ
Sbjct  120  DQRTFGGWQLADLVSVDGSVVPAPVAHLARDPLDPLFDVDSVIKVLRGKHSEVKRRLLDQ  179

Query  177  RVVSGIGNIYADEALWRAKVNGAHVAATLRCRRLGAVLHAAADVMREALAKGGTSFDSLY  236
            +VVSGIGNIYADEALWRAKV+GA VAATL  R+LGAVL AAADVMREALAKGGTSFDSLY
Sbjct  180  QVVSGIGNIYADEALWRAKVHGARVAATLTRRQLGAVLDAAADVMREALAKGGTSFDSLY  239

Query  237  VNVNGESGYFERSLDAYGREGENCRRCGAVIRRERFMNRSSFYCPRCQPRPRK  289
            VNVNG+SGYF+RSLDAYGREGE+CRRCGAV+RRE+FMNRSSFYCPRCQPRPR+
Sbjct  240  VNVNGQSGYFDRSLDAYGREGEHCRRCGAVMRREKFMNRSSFYCPRCQPRPRR  292


>gi|118464268|ref|YP_882954.1| formamidopyrimidine-DNA glycosylase [Mycobacterium avium 104]
 gi|254776228|ref|ZP_05217744.1| formamidopyrimidine-DNA glycosylase [Mycobacterium avium subsp. 
avium ATCC 25291]
 gi|166215633|sp|A0QJ66.1|FPG_MYCA1 RecName: Full=Formamidopyrimidine-DNA glycosylase; Short=Fapy-DNA 
glycosylase; AltName: Full=DNA-(apurinic or apyrimidinic 
site) lyase mutM; Short=AP lyase mutM
 gi|118165555|gb|ABK66452.1| formamidopyrimidine-DNA glycosylase [Mycobacterium avium 104]
Length=283

 Score =  488 bits (1257),  Expect = 3e-136, Method: Compositional matrix adjust.
 Identities = 243/288 (85%), Positives = 261/288 (91%), Gaps = 6/288 (2%)

Query  1    MPELPEVEVVRRGLQAHVTGRTITEVRVHHPRAVRRHDAGPADLTARLRGARINGTDRRG  60
            MPELPEVEVVRRGL +HV G+TI  VRVHHPRAVRRH+AGPADLTARL GARI GTDRRG
Sbjct  1    MPELPEVEVVRRGLHSHVVGKTIGAVRVHHPRAVRRHEAGPADLTARLLGARITGTDRRG  60

Query  61   KYLWLTLNTAGVHRPTDTALVVHLGMSGQMLLGAVPCAAHVRISALLDDGTVLSFADQRT  120
            KYLWL L+        DTALVVHLGMSGQMLLGAVP A HVRISALLDDGTVLSFADQRT
Sbjct  61   KYLWLLLDG------RDTALVVHLGMSGQMLLGAVPRAEHVRISALLDDGTVLSFADQRT  114

Query  121  FGGWLLADLVTVDGSVVPVPVAHLARDPLDPRFDCDAVVKVLRRKHSELKRQLLDQRVVS  180
            FGGW+LADL+ VDGSVVP PVAHLARDPLDPRFD DAVVKVLRRKHSE+KRQLLDQ+VVS
Sbjct  115  FGGWMLADLLEVDGSVVPEPVAHLARDPLDPRFDADAVVKVLRRKHSEIKRQLLDQQVVS  174

Query  181  GIGNIYADEALWRAKVNGAHVAATLRCRRLGAVLHAAADVMREALAKGGTSFDSLYVNVN  240
            GIGNIYADEALWRAKV+GA +A  L  ++L AVL AAADVMR+ALAKGGTSFDSLYVNVN
Sbjct  175  GIGNIYADEALWRAKVHGARIADALTRKQLTAVLDAAADVMRDALAKGGTSFDSLYVNVN  234

Query  241  GESGYFERSLDAYGREGENCRRCGAVIRRERFMNRSSFYCPRCQPRPR  288
            GESGYF+RSLDAYGREGE+CRRCGAV+RRE+FMNRSSFYCP+CQPRPR
Sbjct  235  GESGYFDRSLDAYGREGESCRRCGAVMRREKFMNRSSFYCPKCQPRPR  282


>gi|41409092|ref|NP_961928.1| formamidopyrimidine-DNA glycosylase [Mycobacterium avium subsp. 
paratuberculosis K-10]
 gi|81700438|sp|Q73VL9.3|FPG_MYCPA RecName: Full=Formamidopyrimidine-DNA glycosylase; Short=Fapy-DNA 
glycosylase; AltName: Full=DNA-(apurinic or apyrimidinic 
site) lyase mutM; Short=AP lyase mutM
 gi|41397451|gb|AAS05311.1| Fpg [Mycobacterium avium subsp. paratuberculosis K-10]
 gi|336459094|gb|EGO38043.1| formamidopyrimidine-DNA glycosylase Fpg [Mycobacterium avium 
subsp. paratuberculosis S397]
Length=283

 Score =  486 bits (1251),  Expect = 2e-135, Method: Compositional matrix adjust.
 Identities = 241/288 (84%), Positives = 262/288 (91%), Gaps = 6/288 (2%)

Query  1    MPELPEVEVVRRGLQAHVTGRTITEVRVHHPRAVRRHDAGPADLTARLRGARINGTDRRG  60
            MPELPEVEVVRRGL AHV G+TI  VRVHHPRAVRRH+AGPADLTARL GARI GTDRRG
Sbjct  1    MPELPEVEVVRRGLHAHVVGKTIGAVRVHHPRAVRRHEAGPADLTARLLGARITGTDRRG  60

Query  61   KYLWLTLNTAGVHRPTDTALVVHLGMSGQMLLGAVPCAAHVRISALLDDGTVLSFADQRT  120
            KYLWL L+        DTALVVHLGMSGQMLLGAVP A HVRISALLDDGTVLSFADQRT
Sbjct  61   KYLWLLLDGC------DTALVVHLGMSGQMLLGAVPRAEHVRISALLDDGTVLSFADQRT  114

Query  121  FGGWLLADLVTVDGSVVPVPVAHLARDPLDPRFDCDAVVKVLRRKHSELKRQLLDQRVVS  180
            FGGW+LADL+ VDGS++P PVAHLARDPLDPRFD  AVVKVLRRKHSE+KRQLLDQ+VVS
Sbjct  115  FGGWMLADLLEVDGSILPRPVAHLARDPLDPRFDAAAVVKVLRRKHSEIKRQLLDQQVVS  174

Query  181  GIGNIYADEALWRAKVNGAHVAATLRCRRLGAVLHAAADVMREALAKGGTSFDSLYVNVN  240
            GIGNIYADEALWRAKV+GA +AAT+  R+L AVL AAA+VMR+ALA+GGTSFDSLYVNVN
Sbjct  175  GIGNIYADEALWRAKVHGARIAATMTGRQLTAVLDAAAEVMRDALAQGGTSFDSLYVNVN  234

Query  241  GESGYFERSLDAYGREGENCRRCGAVIRRERFMNRSSFYCPRCQPRPR  288
            GESGYF+RSLDAYGREGE+CRRCGAV+RRE+FMNRSSFYCP+CQPRPR
Sbjct  235  GESGYFDRSLDAYGREGESCRRCGAVMRREKFMNRSSFYCPKCQPRPR  282


>gi|254822110|ref|ZP_05227111.1| formamidopyrimidine-DNA glycosylase [Mycobacterium intracellulare 
ATCC 13950]
Length=282

 Score =  484 bits (1245),  Expect = 8e-135, Method: Compositional matrix adjust.
 Identities = 241/288 (84%), Positives = 258/288 (90%), Gaps = 7/288 (2%)

Query  1    MPELPEVEVVRRGLQAHVTGRTITEVRVHHPRAVRRHDAGPADLTARLRGARINGTDRRG  60
            MPELPEVEVVRRGL AHV G+TIT VRVHHPRAVRRH+AG ADLTARL   RI GTDRRG
Sbjct  1    MPELPEVEVVRRGLHAHVVGKTITAVRVHHPRAVRRHEAGAADLTARLLNDRITGTDRRG  60

Query  61   KYLWLTLNTAGVHRPTDTALVVHLGMSGQMLLGAVPCAAHVRISALLDDGTVLSFADQRT  120
            KYLWL L++       D ALVVHLGMSGQMLLGAVP A HVRISALLDDGTVLSFADQRT
Sbjct  61   KYLWLLLDS-------DAALVVHLGMSGQMLLGAVPRADHVRISALLDDGTVLSFADQRT  113

Query  121  FGGWLLADLVTVDGSVVPVPVAHLARDPLDPRFDCDAVVKVLRRKHSELKRQLLDQRVVS  180
            FGGW+LADLV VDGSVVP PVAHLARDPLDPRFD DAVVKVLRRKHSE+KRQLLDQ+VVS
Sbjct  114  FGGWMLADLVEVDGSVVPEPVAHLARDPLDPRFDADAVVKVLRRKHSEIKRQLLDQQVVS  173

Query  181  GIGNIYADEALWRAKVNGAHVAATLRCRRLGAVLHAAADVMREALAKGGTSFDSLYVNVN  240
            GIGNIYADEALWRAKV+GA +A  L  ++L AVL AAADVMR+ALAKGGTSFDSLYVNVN
Sbjct  174  GIGNIYADEALWRAKVHGARIADALTRKQLTAVLDAAADVMRDALAKGGTSFDSLYVNVN  233

Query  241  GESGYFERSLDAYGREGENCRRCGAVIRRERFMNRSSFYCPRCQPRPR  288
            GESGYF+RSLDAYGREG+ CRRCGAV+RRE+FMNRSSFYCP+CQPRPR
Sbjct  234  GESGYFDRSLDAYGREGQGCRRCGAVMRREKFMNRSSFYCPKCQPRPR  281


>gi|126434518|ref|YP_001070209.1| formamidopyrimidine-DNA glycosylase [Mycobacterium sp. JLS]
 gi|166215636|sp|A3PXU1.1|FPG_MYCSJ RecName: Full=Formamidopyrimidine-DNA glycosylase; Short=Fapy-DNA 
glycosylase; AltName: Full=DNA-(apurinic or apyrimidinic 
site) lyase mutM; Short=AP lyase mutM
 gi|126234318|gb|ABN97718.1| Formamidopyrimidine-DNA glycosylase / DNA-(apurinic or apyrimidinic 
site) lyase [Mycobacterium sp. JLS]
Length=296

 Score =  466 bits (1198),  Expect = 2e-129, Method: Compositional matrix adjust.
 Identities = 233/294 (80%), Positives = 253/294 (87%), Gaps = 8/294 (2%)

Query  1    MPELPEVEVVRRGLQAHVTGRTITEVRVHHPRAVRRHDAGPADLTARLRGARINGTDRRG  60
            MPELPEVEVVRRGL AHVTG+ IT VRVHHPRAVRRH+AGPADLTARL G RI GT RRG
Sbjct  1    MPELPEVEVVRRGLDAHVTGKAITAVRVHHPRAVRRHEAGPADLTARLLGMRITGTGRRG  60

Query  61   KYLWLTLNTAGVHRP------TDTALVVHLGMSGQMLLGAVPCAAHVRISALLDDGTVLS  114
            KYLWLTL+  G   P      +  ALVVHLGMSGQMLLG +P   H+RI+ALLDDGT LS
Sbjct  61   KYLWLTLD--GGDEPLARRAESSVALVVHLGMSGQMLLGPIPKEDHLRIAALLDDGTALS  118

Query  115  FADQRTFGGWLLADLVTVDGSVVPVPVAHLARDPLDPRFDCDAVVKVLRRKHSELKRQLL  174
            F DQRTFGGWLLADLVTVDG+ VPVPVAH+ARDPLDPRFD DAVVKVLR KHSE+KRQLL
Sbjct  119  FVDQRTFGGWLLADLVTVDGTDVPVPVAHVARDPLDPRFDRDAVVKVLRGKHSEIKRQLL  178

Query  175  DQRVVSGIGNIYADEALWRAKVNGAHVAATLRCRRLGAVLHAAADVMREALAKGGTSFDS  234
            DQ VVSGIGNIYADEALWRAKVNGA +A +L   +L  +L  AADVMR+AL +GGTSFDS
Sbjct  179  DQTVVSGIGNIYADEALWRAKVNGARLAESLTKPKLAEILDHAADVMRDALGQGGTSFDS  238

Query  235  LYVNVNGESGYFERSLDAYGREGENCRRCGAVIRRERFMNRSSFYCPRCQPRPR  288
            LYVNVNGESGYF+RSLDAYGREGE CRRCGA++RRE+FMNRSSFYCPRCQPRPR
Sbjct  239  LYVNVNGESGYFDRSLDAYGREGEPCRRCGAIMRREKFMNRSSFYCPRCQPRPR  292


>gi|108798918|ref|YP_639115.1| formamidopyrimidine-DNA glycosylase [Mycobacterium sp. MCS]
 gi|119868033|ref|YP_937985.1| formamidopyrimidine-DNA glycosylase [Mycobacterium sp. KMS]
 gi|123369434|sp|Q1BAM5.1|FPG_MYCSS RecName: Full=Formamidopyrimidine-DNA glycosylase; Short=Fapy-DNA 
glycosylase; AltName: Full=DNA-(apurinic or apyrimidinic 
site) lyase mutM; Short=AP lyase mutM
 gi|166215637|sp|A1UED7.1|FPG_MYCSK RecName: Full=Formamidopyrimidine-DNA glycosylase; Short=Fapy-DNA 
glycosylase; AltName: Full=DNA-(apurinic or apyrimidinic 
site) lyase mutM; Short=AP lyase mutM
 gi|108769337|gb|ABG08059.1| DNA-(apurinic or apyrimidinic site) lyase / Formamidopyrimidine-DNA 
glycosylase [Mycobacterium sp. MCS]
 gi|119694122|gb|ABL91195.1| DNA-(apurinic or apyrimidinic site) lyase [Mycobacterium sp. 
KMS]
Length=296

 Score =  462 bits (1189),  Expect = 3e-128, Method: Compositional matrix adjust.
 Identities = 229/292 (79%), Positives = 250/292 (86%), Gaps = 4/292 (1%)

Query  1    MPELPEVEVVRRGLQAHVTGRTITEVRVHHPRAVRRHDAGPADLTARLRGARINGTDRRG  60
            MPELPEVEVVRRGL AHVTG+ IT VRVHHPRAVRRH+AGPADLTARL G RI GT RRG
Sbjct  1    MPELPEVEVVRRGLDAHVTGKAITAVRVHHPRAVRRHEAGPADLTARLLGMRITGTGRRG  60

Query  61   KYLWLTLNTA----GVHRPTDTALVVHLGMSGQMLLGAVPCAAHVRISALLDDGTVLSFA  116
            KYLWLTL+           +  ALVVHLGMSGQMLLG +P   H+RI+AL DDGT LSF 
Sbjct  61   KYLWLTLDDGDEPLARRAESSVALVVHLGMSGQMLLGPIPKEDHLRIAALFDDGTALSFV  120

Query  117  DQRTFGGWLLADLVTVDGSVVPVPVAHLARDPLDPRFDCDAVVKVLRRKHSELKRQLLDQ  176
            DQRTFGGWLLADLVTVDG+ VPVPVAH+ARDPLDPRFD DAVVKVLR KHSE+KRQLLDQ
Sbjct  121  DQRTFGGWLLADLVTVDGTDVPVPVAHVARDPLDPRFDRDAVVKVLRGKHSEIKRQLLDQ  180

Query  177  RVVSGIGNIYADEALWRAKVNGAHVAATLRCRRLGAVLHAAADVMREALAKGGTSFDSLY  236
             VVSGIGNIYADEALWRAKVNGA +A +L   +L  +L  AADVMR+AL +GGTSFDSLY
Sbjct  181  TVVSGIGNIYADEALWRAKVNGARLAESLTKPKLAEILDHAADVMRDALGQGGTSFDSLY  240

Query  237  VNVNGESGYFERSLDAYGREGENCRRCGAVIRRERFMNRSSFYCPRCQPRPR  288
            VNVNGESGYF+RSLDAYGREGE CRRCGA++RR++FMNRSSFYCPRCQPRPR
Sbjct  241  VNVNGESGYFDRSLDAYGREGEPCRRCGAIMRRDKFMNRSSFYCPRCQPRPR  292


>gi|120403164|ref|YP_952993.1| formamidopyrimidine-DNA glycosylase [Mycobacterium vanbaalenii 
PYR-1]
 gi|166215640|sp|A1T737.1|FPG_MYCVP RecName: Full=Formamidopyrimidine-DNA glycosylase; Short=Fapy-DNA 
glycosylase; AltName: Full=DNA-(apurinic or apyrimidinic 
site) lyase mutM; Short=AP lyase mutM
 gi|119955982|gb|ABM12987.1| DNA-(apurinic or apyrimidinic site) lyase [Mycobacterium vanbaalenii 
PYR-1]
Length=293

 Score =  462 bits (1188),  Expect = 3e-128, Method: Compositional matrix adjust.
 Identities = 228/292 (79%), Positives = 251/292 (86%), Gaps = 4/292 (1%)

Query  1    MPELPEVEVVRRGLQAHVTGRTITEVRVHHPRAVRRHDAGPADLTARLRGARINGTDRRG  60
            MPELPEVEVVRRGL  HVTGRT+T VRVHHPRAVRRH+AGPADLTARL    I GT RRG
Sbjct  1    MPELPEVEVVRRGLAEHVTGRTVTAVRVHHPRAVRRHEAGPADLTARLLDTTITGTGRRG  60

Query  61   KYLWLTLNTAG----VHRPTDTALVVHLGMSGQMLLGAVPCAAHVRISALLDDGTVLSFA  116
            KYLWLTL          R ++ ALVVHLGMSGQMLLG VP A H+RI+ALLDDGT LSF 
Sbjct  61   KYLWLTLGDGADEPLARRESNFALVVHLGMSGQMLLGDVPNANHLRIAALLDDGTTLSFV  120

Query  117  DQRTFGGWLLADLVTVDGSVVPVPVAHLARDPLDPRFDCDAVVKVLRRKHSELKRQLLDQ  176
            DQRTFGGW+LADLVTVDGS VP PVAH+ARDPLDP FD DAVVKVLRRKHSE+KRQLLDQ
Sbjct  121  DQRTFGGWMLADLVTVDGSDVPAPVAHIARDPLDPLFDRDAVVKVLRRKHSEIKRQLLDQ  180

Query  177  RVVSGIGNIYADEALWRAKVNGAHVAATLRCRRLGAVLHAAADVMREALAKGGTSFDSLY  236
             VVSGIGNIYADE+LWRAK+NGA +A+ +   +L  +L AAADVM +ALA+GGTSFDSLY
Sbjct  181  TVVSGIGNIYADESLWRAKINGARLASGVSRAKLAELLGAAADVMTDALAQGGTSFDSLY  240

Query  237  VNVNGESGYFERSLDAYGREGENCRRCGAVIRRERFMNRSSFYCPRCQPRPR  288
            VNVNGESGYF+RSLDAYGREGE CRRCGA++RR++FMNRSSFYCPRCQPRPR
Sbjct  241  VNVNGESGYFDRSLDAYGREGEPCRRCGAIMRRDKFMNRSSFYCPRCQPRPR  292


>gi|15827876|ref|NP_302139.1| formamidopyrimidine-DNA glycosylase [Mycobacterium leprae TN]
 gi|221230353|ref|YP_002503769.1| formamidopyrimidine-DNA glycosylase [Mycobacterium leprae Br4923]
 gi|7531120|sp|O69470.3|FPG_MYCLE RecName: Full=Formamidopyrimidine-DNA glycosylase; Short=Fapy-DNA 
glycosylase; AltName: Full=DNA-(apurinic or apyrimidinic 
site) lyase mutM; Short=AP lyase mutM
 gi|254789446|sp|B8ZRZ2.1|FPG_MYCLB RecName: Full=Formamidopyrimidine-DNA glycosylase; Short=Fapy-DNA 
glycosylase; AltName: Full=DNA-(apurinic or apyrimidinic 
site) lyase mutM; Short=AP lyase mutM
 gi|3150225|emb|CAA19197.1| formamidopyrimidine-dna glycosylase [Mycobacterium leprae]
 gi|13093429|emb|CAC30611.1| formamidopyrimidine-DNA glycosylase [Mycobacterium leprae]
 gi|219933460|emb|CAR71753.1| formamidopyrimidine-DNA glycosylase [Mycobacterium leprae Br4923]
Length=282

 Score =  452 bits (1163),  Expect = 2e-125, Method: Compositional matrix adjust.
 Identities = 233/289 (81%), Positives = 252/289 (88%), Gaps = 7/289 (2%)

Query  1    MPELPEVEVVRRGLQAHVTGRTITEVRVHHPRAVRRHDAGPADLTARLRGARINGTDRRG  60
            MPELPEVEVVRRGLQ ++ G+TIT VRVHHPRAVRRH AGP DLT RL G RING DRRG
Sbjct  1    MPELPEVEVVRRGLQDYIVGKTITAVRVHHPRAVRRHVAGPTDLTNRLLGTRINGIDRRG  60

Query  61   KYLWLTLNTAGVHRPTDTALVVHLGMSGQMLLGAVPCAAHVRISALLDDGTVLSFADQRT  120
            KYLW  L+T       D ALVVHLGMSGQMLLG VP   HVRISAL DDGTVL+F DQRT
Sbjct  61   KYLWFLLDT-------DIALVVHLGMSGQMLLGTVPRVDHVRISALFDDGTVLNFTDQRT  113

Query  121  FGGWLLADLVTVDGSVVPVPVAHLARDPLDPRFDCDAVVKVLRRKHSELKRQLLDQRVVS  180
             GGWLLADL+TVDGSV+PVPVAHLARDP DPRFD +AVVKVLR KHSELKRQLLDQ+ VS
Sbjct  114  LGGWLLADLMTVDGSVLPVPVAHLARDPFDPRFDVEAVVKVLRCKHSELKRQLLDQQTVS  173

Query  181  GIGNIYADEALWRAKVNGAHVAATLRCRRLGAVLHAAADVMREALAKGGTSFDSLYVNVN  240
            GIGNIYADEALWRA+V+GA +AATL  R+L AVL AAADVMR++LAKGGTSFDSLYVNVN
Sbjct  174  GIGNIYADEALWRAEVHGARIAATLTRRQLAAVLDAAADVMRDSLAKGGTSFDSLYVNVN  233

Query  241  GESGYFERSLDAYGREGENCRRCGAVIRRERFMNRSSFYCPRCQPRPRK  289
            GESGYF+RSLDAYGREGE CRRCGAV+ RE+FMNRSSFYCPRCQPRPR+
Sbjct  234  GESGYFDRSLDAYGREGEGCRRCGAVMHREKFMNRSSFYCPRCQPRPRR  282


>gi|145224770|ref|YP_001135448.1| formamidopyrimidine-DNA glycosylase [Mycobacterium gilvum PYR-GCK]
 gi|315445100|ref|YP_004077979.1| DNA-(apurinic or apyrimidinic site) lyase ;Formamidopyrimidine-DNA 
glycosylase [Mycobacterium sp. Spyr1]
 gi|189044665|sp|A4TE57.1|FPG_MYCGI RecName: Full=Formamidopyrimidine-DNA glycosylase; Short=Fapy-DNA 
glycosylase; AltName: Full=DNA-(apurinic or apyrimidinic 
site) lyase mutM; Short=AP lyase mutM
 gi|145217256|gb|ABP46660.1| DNA-(apurinic or apyrimidinic site) lyase [Mycobacterium gilvum 
PYR-GCK]
 gi|315263403|gb|ADU00145.1| DNA-(apurinic or apyrimidinic site) lyase ;Formamidopyrimidine-DNA 
glycosylase [Mycobacterium sp. Spyr1]
Length=282

 Score =  447 bits (1150),  Expect = 1e-123, Method: Compositional matrix adjust.
 Identities = 221/288 (77%), Positives = 245/288 (86%), Gaps = 7/288 (2%)

Query  1    MPELPEVEVVRRGLQAHVTGRTITEVRVHHPRAVRRHDAGPADLTARLRGARINGTDRRG  60
            MPELPEVEVVRRGL AHVTGRTI+ VRVHHPRAVRRH+AGPADLTARL  + I GT RRG
Sbjct  1    MPELPEVEVVRRGLAAHVTGRTISAVRVHHPRAVRRHEAGPADLTARLLDSVITGTGRRG  60

Query  61   KYLWLTLNTAGVHRPTDTALVVHLGMSGQMLLGAVPCAAHVRISALLDDGTVLSFADQRT  120
            KYLWLTL          +A+VVHLGMSGQMLLG V    H+RI+ LLDDGT LSF DQRT
Sbjct  61   KYLWLTLGDG-------SAVVVHLGMSGQMLLGPVRNENHLRIAVLLDDGTALSFVDQRT  113

Query  121  FGGWLLADLVTVDGSVVPVPVAHLARDPLDPRFDCDAVVKVLRRKHSELKRQLLDQRVVS  180
            FGGW+LADLVTVDGS VP PVAH+ARDPLDP FD  AVV VLRRKHSE+KRQLLDQ VVS
Sbjct  114  FGGWMLADLVTVDGSDVPAPVAHIARDPLDPLFDRAAVVNVLRRKHSEIKRQLLDQTVVS  173

Query  181  GIGNIYADEALWRAKVNGAHVAATLRCRRLGAVLHAAADVMREALAKGGTSFDSLYVNVN  240
            GIGNIYADE+LWRAK+NGA +A+ +   +L  +L AA DVM +ALA+GGTSFDSLYVNVN
Sbjct  174  GIGNIYADESLWRAKINGARLASGVSKAKLAELLDAATDVMTDALAQGGTSFDSLYVNVN  233

Query  241  GESGYFERSLDAYGREGENCRRCGAVIRRERFMNRSSFYCPRCQPRPR  288
            GESGYF+RSLDAYGREGE CRRCGA++RR++FMNRSSFYCPRCQPRPR
Sbjct  234  GESGYFDRSLDAYGREGEPCRRCGAIMRRDKFMNRSSFYCPRCQPRPR  281


>gi|118470267|ref|YP_886759.1| formamidopyrimidine-DNA glycosylase [Mycobacterium smegmatis 
str. MC2 155]
 gi|166215635|sp|A0QV21.1|FPG_MYCS2 RecName: Full=Formamidopyrimidine-DNA glycosylase; Short=Fapy-DNA 
glycosylase; AltName: Full=DNA-(apurinic or apyrimidinic 
site) lyase mutM; Short=AP lyase mutM
 gi|118171554|gb|ABK72450.1| formamidopyrimidine-DNA glycosylase [Mycobacterium smegmatis 
str. MC2 155]
Length=285

 Score =  443 bits (1140),  Expect = 1e-122, Method: Compositional matrix adjust.
 Identities = 220/288 (77%), Positives = 243/288 (85%), Gaps = 7/288 (2%)

Query  1    MPELPEVEVVRRGLQAHVTGRTITEVRVHHPRAVRRHDAGPADLTARLRGARINGTDRRG  60
            MPELPEVEVVRRGL  HVTG+TIT VRVHHPRAVRRH+AGPADLTARL   RI GT RRG
Sbjct  1    MPELPEVEVVRRGLAEHVTGKTITGVRVHHPRAVRRHEAGPADLTARLLDVRITGTGRRG  60

Query  61   KYLWLTLNTAGVHRPTDTALVVHLGMSGQMLLGAVPCAAHVRISALLDDGTVLSFADQRT  120
            KYLWLTL+ +        ALVVHLGMSGQMLLG +    H+RI+A+LDDGT LSF DQRT
Sbjct  61   KYLWLTLDDSA-------ALVVHLGMSGQMLLGPIRDTRHLRIAAVLDDGTALSFVDQRT  113

Query  121  FGGWLLADLVTVDGSVVPVPVAHLARDPLDPRFDCDAVVKVLRRKHSELKRQLLDQRVVS  180
            FGGW L ++VTVDG+ VP PVAH+ARDPLDP FD D VV VLR KHSE+KRQLLDQ VVS
Sbjct  114  FGGWQLTEMVTVDGTDVPEPVAHIARDPLDPLFDRDRVVTVLRGKHSEIKRQLLDQTVVS  173

Query  181  GIGNIYADEALWRAKVNGAHVAATLRCRRLGAVLHAAADVMREALAKGGTSFDSLYVNVN  240
            GIGNIYADEALWR K+NGA +AA L  RRL  +L AAA+VM +AL +GGTSFDSLYVNVN
Sbjct  174  GIGNIYADEALWRTKINGARIAAALPRRRLAELLDAAAEVMTDALGQGGTSFDSLYVNVN  233

Query  241  GESGYFERSLDAYGREGENCRRCGAVIRRERFMNRSSFYCPRCQPRPR  288
            GESGYF+RSLDAYGREGE CRRCGA++RRE+FMNRSSFYCPRCQPRPR
Sbjct  234  GESGYFDRSLDAYGREGEPCRRCGAIMRREKFMNRSSFYCPRCQPRPR  281


>gi|333991296|ref|YP_004523910.1| formamidopyrimidine-DNA glycosylase Fpg [Mycobacterium sp. JDM601]
 gi|333487264|gb|AEF36656.1| formamidopyrimidine-DNA glycosylase Fpg [Mycobacterium sp. JDM601]
Length=278

 Score =  425 bits (1092),  Expect = 4e-117, Method: Compositional matrix adjust.
 Identities = 213/284 (75%), Positives = 234/284 (83%), Gaps = 7/284 (2%)

Query  1    MPELPEVEVVRRGLQAHVTGRTITEVRVHHPRAVRRHDAGPADLTARLRGARINGTDRRG  60
            MPELPEVEVVRRGL AH+ GRTI  VRVHHPRAVRRHDAGPADLT RL  ARI GTDRRG
Sbjct  1    MPELPEVEVVRRGLDAHLVGRTIAGVRVHHPRAVRRHDAGPADLTGRLLDARIVGTDRRG  60

Query  61   KYLWLTLNTAGVHRPTDTALVVHLGMSGQMLLGAVPCAAHVRISALLDDGTVLSFADQRT  120
            KYLWL L+T       D ALVVHLGMSGQMLLG +P   H+RI+A+LDDGT +SF DQRT
Sbjct  61   KYLWLLLST-------DEALVVHLGMSGQMLLGDLPDTRHLRIAAVLDDGTKVSFVDQRT  113

Query  121  FGGWLLADLVTVDGSVVPVPVAHLARDPLDPRFDCDAVVKVLRRKHSELKRQLLDQRVVS  180
            FGGW L DLV VD SVVP+PVAHLARDPLDPRFD ++VV VLRRKHSE+KRQLLDQ VVS
Sbjct  114  FGGWQLTDLVAVDDSVVPLPVAHLARDPLDPRFDAESVVNVLRRKHSEIKRQLLDQTVVS  173

Query  181  GIGNIYADEALWRAKVNGAHVAATLRCRRLGAVLHAAADVMREALAKGGTSFDSLYVNVN  240
            GIGNIYADEALWRA + G  +A  L   RL A+L +A  VM +ALA GGTSFDSLYVNVN
Sbjct  174  GIGNIYADEALWRAGIRGTRMADALSRPRLRALLESARAVMSDALAAGGTSFDSLYVNVN  233

Query  241  GESGYFERSLDAYGREGENCRRCGAVIRRERFMNRSSFYCPRCQ  284
            GESGYF RSLDAYGRE E CRRCG +IRR++F NRSS+YCP+CQ
Sbjct  234  GESGYFSRSLDAYGREDEPCRRCGTLIRRQKFTNRSSYYCPKCQ  277


>gi|325675925|ref|ZP_08155608.1| DNA-formamidopyrimidine glycosylase [Rhodococcus equi ATCC 33707]
 gi|325553163|gb|EGD22842.1| DNA-formamidopyrimidine glycosylase [Rhodococcus equi ATCC 33707]
Length=288

 Score =  381 bits (979),  Expect = 7e-104, Method: Compositional matrix adjust.
 Identities = 194/290 (67%), Positives = 221/290 (77%), Gaps = 8/290 (2%)

Query  1    MPELPEVEVVRRGLQAHVTGRTITEVRVHHPRAVRRHDAGPADLTARLRGARINGTDRRG  60
            MPELPEVEVVRRGL+AHV G TI +V V HPRAVRRH  G  DL  RL G  + G +RRG
Sbjct  1    MPELPEVEVVRRGLEAHVVGHTIADVEVLHPRAVRRHLPGSLDLAGRLEGQTVVGAERRG  60

Query  61   KYLWLTLNTAGVHRPTDTALVVHLGMSGQMLLG--AVPCAAHVRISALLDDGTVLSFADQ  118
            KYLWL L       P+  A+VVHLGMSGQML+    VP   H+RI A L+ G  L F DQ
Sbjct  61   KYLWLVLE------PSSVAIVVHLGMSGQMLVQDPTVPDEKHLRIRARLESGIDLRFVDQ  114

Query  119  RTFGGWLLADLVTVDGSVVPVPVAHLARDPLDPRFDCDAVVKVLRRKHSELKRQLLDQRV  178
            RTFGGW LADLVTVDG+VVP  VAH+ARDPLDPRFD D VVK LR KH+E+KR LLDQ V
Sbjct  115  RTFGGWALADLVTVDGTVVPDSVAHIARDPLDPRFDPDLVVKALRAKHTEIKRALLDQTV  174

Query  179  VSGIGNIYADEALWRAKVNGAHVAATLRCRRLGAVLHAAADVMREALAKGGTSFDSLYVN  238
            VSG+GNIYADEALWRA+++G      L   RL  +L AA DVM EAL +GGTSFD+LYVN
Sbjct  175  VSGVGNIYADEALWRAEIHGNRPTDKLSGPRLRVLLDAARDVMTEALDQGGTSFDALYVN  234

Query  239  VNGESGYFERSLDAYGREGENCRRCGAVIRRERFMNRSSFYCPRCQPRPR  288
            VNG+SGYF+RSL+AYG+E   CRRCGA IRRE+FMNRSS+ CP+CQPRPR
Sbjct  235  VNGQSGYFDRSLNAYGQENLPCRRCGAPIRREKFMNRSSYSCPKCQPRPR  284


>gi|226365984|ref|YP_002783767.1| formamidopyrimidine-DNA glycosylase [Rhodococcus opacus B4]
 gi|254789448|sp|C1B2Q5.1|FPG_RHOOB RecName: Full=Formamidopyrimidine-DNA glycosylase; Short=Fapy-DNA 
glycosylase; AltName: Full=DNA-(apurinic or apyrimidinic 
site) lyase mutM; Short=AP lyase mutM
 gi|226244474|dbj|BAH54822.1| formamidopyrimidine-DNA glycosylase/AP lyase [Rhodococcus opacus 
B4]
Length=289

 Score =  374 bits (959),  Expect = 1e-101, Method: Compositional matrix adjust.
 Identities = 191/291 (66%), Positives = 218/291 (75%), Gaps = 8/291 (2%)

Query  1    MPELPEVEVVRRGLQAHVTGRTITEVRVHHPRAVRRHDAGPADLTARLRGARINGTDRRG  60
            MPELPEVEVVRRGL+ H+ G +I  V + HPRA+RRH  G ADL  +L G RI G DRRG
Sbjct  1    MPELPEVEVVRRGLERHIVGASIDSVDILHPRAIRRHLPGAADLAGQLTGERIAGADRRG  60

Query  61   KYLWLTLNTAGVHRPTDTALVVHLGMSGQMLLGA--VPCAAHVRISALLDDGTVLSFADQ  118
            KYLWL L       P+  ALVVHLGMSGQML+    +P   H+RI A LD G  L F DQ
Sbjct  61   KYLWLVLE------PSTVALVVHLGMSGQMLVQPPELPTEKHLRIRARLDSGLDLRFVDQ  114

Query  119  RTFGGWLLADLVTVDGSVVPVPVAHLARDPLDPRFDCDAVVKVLRRKHSELKRQLLDQRV  178
            RTFGGW LA LV VDGS+VP  VAH+ARDPLD RFD  A VKV+R KHSE+KR LLDQ V
Sbjct  115  RTFGGWALAPLVEVDGSLVPDSVAHIARDPLDSRFDLAATVKVVRGKHSEIKRVLLDQTV  174

Query  179  VSGIGNIYADEALWRAKVNGAHVAATLRCRRLGAVLHAAADVMREALAKGGTSFDSLYVN  238
            VSGIGNIYADEALWRA+++G  +   L   R+GAVL AA  VMREAL++GGTSFD+LYVN
Sbjct  175  VSGIGNIYADEALWRAQIHGNRLTDRLTGPRIGAVLTAAQQVMREALSQGGTSFDALYVN  234

Query  239  VNGESGYFERSLDAYGREGENCRRCGAVIRRERFMNRSSFYCPRCQPRPRK  289
            VNGESGYF+RSL AYG+E   C RCG  IRRE+FMNRSSF CP+CQ  PR+
Sbjct  235  VNGESGYFDRSLSAYGQEDRPCPRCGTAIRREKFMNRSSFSCPKCQRAPRR  285


>gi|111023482|ref|YP_706454.1| formamidopyrimidine-DNA glycosylase [Rhodococcus jostii RHA1]
 gi|123045457|sp|Q0S2E0.1|FPG_RHOSR RecName: Full=Formamidopyrimidine-DNA glycosylase; Short=Fapy-DNA 
glycosylase; AltName: Full=DNA-(apurinic or apyrimidinic 
site) lyase mutM; Short=AP lyase mutM
 gi|110823012|gb|ABG98296.1| DNA-formamidopyrimidine glycosylase [Rhodococcus jostii RHA1]
Length=292

 Score =  372 bits (955),  Expect = 4e-101, Method: Compositional matrix adjust.
 Identities = 188/291 (65%), Positives = 217/291 (75%), Gaps = 8/291 (2%)

Query  1    MPELPEVEVVRRGLQAHVTGRTITEVRVHHPRAVRRHDAGPADLTARLRGARINGTDRRG  60
            MPELPEVEVVRRGL+ H+ G +I  V + HPRA+RRH  G ADL  +L G RI   DRRG
Sbjct  1    MPELPEVEVVRRGLERHIVGASIDSVDILHPRAIRRHLPGAADLAGQLTGERIASADRRG  60

Query  61   KYLWLTLNTAGVHRPTDTALVVHLGMSGQMLLGA--VPCAAHVRISALLDDGTVLSFADQ  118
            KYLWL L       P+  ALVVHLGMSGQML+    +P   H+RI A LD G  L F DQ
Sbjct  61   KYLWLVLE------PSTVALVVHLGMSGQMLVQPPELPTEKHLRIRARLDSGLDLRFVDQ  114

Query  119  RTFGGWLLADLVTVDGSVVPVPVAHLARDPLDPRFDCDAVVKVLRRKHSELKRQLLDQRV  178
            RTFGGW LA LV VDGS+VP  VAH+ARDPLDPRFD  A VKV+R KH+E+KR LLDQ V
Sbjct  115  RTFGGWALAPLVDVDGSLVPDSVAHIARDPLDPRFDLAATVKVVRGKHTEVKRALLDQTV  174

Query  179  VSGIGNIYADEALWRAKVNGAHVAATLRCRRLGAVLHAAADVMREALAKGGTSFDSLYVN  238
            VSGIGNIYADEALWRA+++G  +   L   ++  VL AA +VMREAL +GGTSFD+LYVN
Sbjct  175  VSGIGNIYADEALWRARIHGNRLTDRLSGPKVREVLTAAQEVMREALTQGGTSFDALYVN  234

Query  239  VNGESGYFERSLDAYGREGENCRRCGAVIRRERFMNRSSFYCPRCQPRPRK  289
            VNGESGYF+RSL AYG+E   C RCG  IRRE+FMNRSSF CP+CQP PR+
Sbjct  235  VNGESGYFDRSLSAYGQEDRPCPRCGTAIRREKFMNRSSFSCPKCQPAPRR  285


>gi|169630336|ref|YP_001703985.1| formamidopyrimidine-DNA glycosylase [Mycobacterium abscessus 
ATCC 19977]
 gi|238688908|sp|B1MDL2.1|FPG_MYCA9 RecName: Full=Formamidopyrimidine-DNA glycosylase; Short=Fapy-DNA 
glycosylase; AltName: Full=DNA-(apurinic or apyrimidinic 
site) lyase mutM; Short=AP lyase mutM
 gi|169242303|emb|CAM63331.1| Formamidopyrimidine-DNA glycosylase (MutM) [Mycobacterium abscessus]
Length=286

 Score =  371 bits (952),  Expect = 9e-101, Method: Compositional matrix adjust.
 Identities = 185/285 (65%), Positives = 219/285 (77%), Gaps = 6/285 (2%)

Query  1    MPELPEVEVVRRGLQAHVTGRTITEVRVHHPRAVRRHDAGPADLTARLRGARINGTDRRG  60
            MPELPEVEVVRRGL  H+ G+TI    V+H RAVRR   G  +L   L G +I+GT RRG
Sbjct  1    MPELPEVEVVRRGLHHHLVGKTIASTLVYHERAVRRQSGGAVELAGLLAGQQISGTGRRG  60

Query  61   KYLWLTLN-TAGVHRPTDTALVVHLGMSGQMLLGAVPCAAHVRISALLDDGTVLSFADQR  119
            KYLWLTL  ++G       ALVVHLGMSGQML+G +    H+RI+A LDDG+VLSF DQR
Sbjct  61   KYLWLTLEGSSGAQ-----ALVVHLGMSGQMLIGPISRPQHLRIAATLDDGSVLSFVDQR  115

Query  120  TFGGWLLADLVTVDGSVVPVPVAHLARDPLDPRFDCDAVVKVLRRKHSELKRQLLDQRVV  179
            TFGGW++ DLVTVDGS +P PVAH+ARDPLD  F+  AVV  LR KH+E+KR LLDQ VV
Sbjct  116  TFGGWMVTDLVTVDGSELPEPVAHIARDPLDELFEIGAVVTRLRGKHTEIKRALLDQTVV  175

Query  180  SGIGNIYADEALWRAKVNGAHVAATLRCRRLGAVLHAAADVMREALAKGGTSFDSLYVNV  239
            SG+GNIYADEALW+A+V+G  +   +   +L  VL +AA VMR ALA+GGTSFD LYVNV
Sbjct  176  SGVGNIYADEALWQARVHGRRLTDGMSRAKLTEVLDSAAAVMRLALAQGGTSFDDLYVNV  235

Query  240  NGESGYFERSLDAYGREGENCRRCGAVIRRERFMNRSSFYCPRCQ  284
            NGESGYF+RSL+AYGREGE CRRCG  +RRE FMNRSS++CP CQ
Sbjct  236  NGESGYFDRSLEAYGREGEPCRRCGRAMRREAFMNRSSYFCPSCQ  280


>gi|229491415|ref|ZP_04385239.1| formamidopyrimidine-DNA glycosylase [Rhodococcus erythropolis 
SK121]
 gi|229321700|gb|EEN87497.1| formamidopyrimidine-DNA glycosylase [Rhodococcus erythropolis 
SK121]
Length=289

 Score =  358 bits (918),  Expect = 7e-97, Method: Compositional matrix adjust.
 Identities = 182/290 (63%), Positives = 212/290 (74%), Gaps = 8/290 (2%)

Query  1    MPELPEVEVVRRGLQAHVTGRTITEVRVHHPRAVRRHDAGPADLTARLRGARINGTDRRG  60
            MPELPEVEVVRRGLQ+H  G  I  V V HPRA+RRH  G  DL  +L G  I   +RRG
Sbjct  1    MPELPEVEVVRRGLQSHAVGAAIEAVEVLHPRAIRRHILGSEDLIGQLTGQTIASAERRG  60

Query  61   KYLWLTLNTAGVHRPTDTALVVHLGMSGQMLLG--AVPCAAHVRISALLDDGTVLSFADQ  118
            KYLWL L  AGV       LVVHLGMSGQML+    V    H+RI   LD G  L F DQ
Sbjct  61   KYLWLVLEPAGV------GLVVHLGMSGQMLVQPPTVDWEKHLRIRLALDSGADLRFVDQ  114

Query  119  RTFGGWLLADLVTVDGSVVPVPVAHLARDPLDPRFDCDAVVKVLRRKHSELKRQLLDQRV  178
            RTFGGW ++ LV VDG+++P  VAH+ARDP+D  FD ++VVKVLR KH+E+KR +LDQ V
Sbjct  115  RTFGGWSISPLVEVDGTMLPESVAHIARDPMDAAFDLESVVKVLRGKHTEIKRAILDQTV  174

Query  179  VSGIGNIYADEALWRAKVNGAHVAATLRCRRLGAVLHAAADVMREALAKGGTSFDSLYVN  238
            VSGIGNIYADE+LWRAK++G  +A TL   +L  +L AA  VM EAL +GGTSFD+LYVN
Sbjct  175  VSGIGNIYADESLWRAKIHGNRIAETLTRPKLRELLTAAHSVMGEALDQGGTSFDALYVN  234

Query  239  VNGESGYFERSLDAYGREGENCRRCGAVIRRERFMNRSSFYCPRCQPRPR  288
            VNGESGYF+RSL AYG+E   C RCGA I+RE+FMNRSSF CPRCQP PR
Sbjct  235  VNGESGYFDRSLSAYGQENLPCPRCGAPIKREKFMNRSSFSCPRCQPTPR  284


>gi|296139285|ref|YP_003646528.1| formamidopyrimidine-DNA glycosylase [Tsukamurella paurometabola 
DSM 20162]
 gi|296027419|gb|ADG78189.1| formamidopyrimidine-DNA glycosylase [Tsukamurella paurometabola 
DSM 20162]
Length=286

 Score =  357 bits (916),  Expect = 1e-96, Method: Compositional matrix adjust.
 Identities = 181/288 (63%), Positives = 219/288 (77%), Gaps = 3/288 (1%)

Query  1    MPELPEVEVVRRGLQAHVTGRTITEVRVHHPRAVRRHDAGPADLTARLRGARINGTDRRG  60
            MPELPEVEVVRRGL  H+ GRT+T V V HPRA RRH AG ADL  ++ GA++   +RRG
Sbjct  1    MPELPEVEVVRRGLADHLVGRTVTAVEVLHPRAARRHVAGDADLIGQVTGAQVTSAERRG  60

Query  61   KYLWLTLNTAGVHRPTDTALVVHLGMSGQMLLGAVPCAAHVRISALLDDGTVLSFADQRT  120
            K+LWL L  AG  RP D A+VVHLGMSGQML+G      H+RI A LDDG VL F DQRT
Sbjct  61   KFLWLPLARAG--RPADAAIVVHLGMSGQMLVGPGD-DRHLRIRAGLDDGAVLRFVDQRT  117

Query  121  FGGWLLADLVTVDGSVVPVPVAHLARDPLDPRFDCDAVVKVLRRKHSELKRQLLDQRVVS  180
            FGGW +  LV VDG++VP  VAH+ARDPLD RFD  AV+  ++ K +E+KR LLDQ V+S
Sbjct  118  FGGWAVDPLVEVDGTLVPESVAHIARDPLDARFDRAAVIARMKAKDTEVKRVLLDQTVIS  177

Query  181  GIGNIYADEALWRAKVNGAHVAATLRCRRLGAVLHAAADVMREALAKGGTSFDSLYVNVN  240
            G+GNIYADEALW ++V+G   A+ L    LG ++  A +VMR+AL +GGTSFDSLYVNVN
Sbjct  178  GVGNIYADEALWLSRVHGRRRASALTKPALGRLVDDATEVMRKALDQGGTSFDSLYVNVN  237

Query  241  GESGYFERSLDAYGREGENCRRCGAVIRRERFMNRSSFYCPRCQPRPR  288
            G+SGYFERSL+AYGR+GE CRRCG ++RRE+FMNR S +CP CQ  PR
Sbjct  238  GQSGYFERSLNAYGRDGEPCRRCGTIMRREQFMNRGSHFCPTCQTAPR  285


>gi|226305919|ref|YP_002765879.1| formamidopyrimidine-DNA glycosylase/AP lyase [Rhodococcus erythropolis 
PR4]
 gi|259647148|sp|C0ZXQ5.1|FPG_RHOE4 RecName: Full=Formamidopyrimidine-DNA glycosylase; Short=Fapy-DNA 
glycosylase; AltName: Full=DNA-(apurinic or apyrimidinic 
site) lyase mutM; Short=AP lyase mutM
 gi|226185036|dbj|BAH33140.1| formamidopyrimidine-DNA glycosylase/AP lyase [Rhodococcus erythropolis 
PR4]
Length=289

 Score =  357 bits (915),  Expect = 2e-96, Method: Compositional matrix adjust.
 Identities = 181/290 (63%), Positives = 212/290 (74%), Gaps = 8/290 (2%)

Query  1    MPELPEVEVVRRGLQAHVTGRTITEVRVHHPRAVRRHDAGPADLTARLRGARINGTDRRG  60
            MPELPEVEVVRRGLQ+H  G  I  V V HPRA+RRH  G  DL  +L G  I   +RRG
Sbjct  1    MPELPEVEVVRRGLQSHAVGAAIEAVEVLHPRAIRRHILGSEDLIGQLTGQTIASAERRG  60

Query  61   KYLWLTLNTAGVHRPTDTALVVHLGMSGQMLLG--AVPCAAHVRISALLDDGTVLSFADQ  118
            KYLWL L  AGV       LVVHLGMSGQML+    V    H+RI   LD G  L F DQ
Sbjct  61   KYLWLVLEPAGV------GLVVHLGMSGQMLVQPPTVDWEKHLRIRLALDSGADLRFVDQ  114

Query  119  RTFGGWLLADLVTVDGSVVPVPVAHLARDPLDPRFDCDAVVKVLRRKHSELKRQLLDQRV  178
            RTFGGW ++ LV VDG+++P  VAH+ARDP+D  FD ++VVKVLR KH+E+KR +LDQ V
Sbjct  115  RTFGGWSISPLVEVDGTMLPESVAHIARDPMDAAFDLESVVKVLRGKHTEIKRAILDQTV  174

Query  179  VSGIGNIYADEALWRAKVNGAHVAATLRCRRLGAVLHAAADVMREALAKGGTSFDSLYVN  238
            VSGIGNIYADE+LWRAK++G  +A +L   +L  +L AA  VM EAL +GGTSFD+LYVN
Sbjct  175  VSGIGNIYADESLWRAKIHGNRIAESLTRPKLRELLTAAHSVMGEALDQGGTSFDALYVN  234

Query  239  VNGESGYFERSLDAYGREGENCRRCGAVIRRERFMNRSSFYCPRCQPRPR  288
            VNGESGYF+RSL AYG+E   C RCGA I+RE+FMNRSSF CPRCQP PR
Sbjct  235  VNGESGYFDRSLSAYGQENLPCPRCGAPIKREKFMNRSSFSCPRCQPTPR  284


>gi|54026154|ref|YP_120396.1| formamidopyrimidine-DNA glycosylase [Nocardia farcinica IFM 10152]
 gi|81679878|sp|Q5YS09.3|FPG_NOCFA RecName: Full=Formamidopyrimidine-DNA glycosylase; Short=Fapy-DNA 
glycosylase; AltName: Full=DNA-(apurinic or apyrimidinic 
site) lyase mutM; Short=AP lyase mutM
 gi|54017662|dbj|BAD59032.1| putative formamidopyrimidine-DNA glycosylase [Nocardia farcinica 
IFM 10152]
Length=294

 Score =  352 bits (902),  Expect = 4e-95, Method: Compositional matrix adjust.
 Identities = 184/285 (65%), Positives = 210/285 (74%), Gaps = 10/285 (3%)

Query  1    MPELPEVEVVRRGLQAHVTGRTITEVRVHHPRAVRRHDAGPADLTARLRGARINGTDRRG  60
            MPELPEVEVVRRGL  HV GR +  V + HPR+VRRH AG ADL AR+ G R+    RRG
Sbjct  1    MPELPEVEVVRRGLAEHVAGRVVGAVTITHPRSVRRHLAGSADLAARMTGRRVRAAQRRG  60

Query  61   KYLWLTLNTAGVHRPT--DTALVVHLGMSGQMLL--GAVPCAAHVRISALLDDGTVLSFA  116
            KYLWLT +  G    T  D ALVVHLGMSGQML+   A P   H  I A LDDG+ L F 
Sbjct  61   KYLWLTFDEPGAADETALDAALVVHLGMSGQMLVQPAAAPVEKHAHIRAALDDGSELRFV  120

Query  117  DQRTFGGWLLADLVTVDGSVVPVPVAHLARDPLDPRFDCDAVVKVLRRKHSELKRQLLDQ  176
            DQRTFGGW LA L  VDGS+VP PVAH+ARDPLDPRFD ++VV  +R K+SE+KR LLDQ
Sbjct  121  DQRTFGGWALAPLAEVDGSLVPEPVAHIARDPLDPRFDAESVVAAIRAKNSEIKRVLLDQ  180

Query  177  RVVSGIGNIYADEALWRAKVNGAHVAATLR---CRRLGAVLHAAADVMREALAKGGTSFD  233
             VVSGIGNIYADE+LWRA +NG  +A+ L     RRL A + A   VM EALA GGTSFD
Sbjct  181  TVVSGIGNIYADESLWRAGINGNRLASGLTRPAVRRLLAEVRA---VMLEALAAGGTSFD  237

Query  234  SLYVNVNGESGYFERSLDAYGREGENCRRCGAVIRRERFMNRSSF  278
            +LYVNVNG+SGYFER+L  YGR+ E CRRCGA I RE+FMNRSS+
Sbjct  238  ALYVNVNGQSGYFERALAVYGRQDEPCRRCGAPIVREKFMNRSSY  282


>gi|343925328|ref|ZP_08764853.1| formamidopyrimidine-DNA glycosylase [Gordonia alkanivorans NBRC 
16433]
 gi|343764767|dbj|GAA11779.1| formamidopyrimidine-DNA glycosylase [Gordonia alkanivorans NBRC 
16433]
Length=283

 Score =  344 bits (883),  Expect = 8e-93, Method: Compositional matrix adjust.
 Identities = 177/289 (62%), Positives = 209/289 (73%), Gaps = 12/289 (4%)

Query  1    MPELPEVEVVRRGLQAHVTGRTITEVRVHHPRAVRRHDAGPADLTARLRGARINGTDRRG  60
            MPELPEVE VR GL+ H+TGRT+T V V HPRA RRH  G  DL  RL G  + G  RRG
Sbjct  1    MPELPEVETVRMGLEKHLTGRTVTAVEVLHPRAARRHLGGEPDLIGRLAGKHVTGVRRRG  60

Query  61   KYLWLTLNTAGVHRPTD-TALVVHLGMSGQMLLG--AVPCAAHVRISALLDDGTVLSFAD  117
            KY+W+      V   TD  ALVVHLGMSGQML+     P   H+RI A LDD   L F D
Sbjct  61   KYMWID-----VADDTDRAALVVHLGMSGQMLIARDGAPDHTHLRIRAHLDDDNELRFVD  115

Query  118  QRTFGGWLLADLVTVDGSVVPVPVAHLARDPLDPRFDCDAVVKVLRRKHSELKRQLLDQR  177
            QRTFGGW L D V      +PV VAH+A DP DP FD  AVV  +R KHSE+KR LLDQ 
Sbjct  116  QRTFGGWHLDDYV----DDIPVSVAHIAPDPFDPAFDAAAVVTRMRAKHSEIKRVLLDQT  171

Query  178  VVSGIGNIYADEALWRAKVNGAHVAATLRCRRLGAVLHAAADVMREALAKGGTSFDSLYV  237
            V+SG+GNIYADEALWRA+++GA +A T+  +++  ++ AA  VM EA+  GGTSFD+LYV
Sbjct  172  VISGVGNIYADEALWRARLHGARIAETISRKKILELIDAATAVMSEAVEVGGTSFDALYV  231

Query  238  NVNGESGYFERSLDAYGREGENCRRCGAVIRRERFMNRSSFYCPRCQPR  286
            NVNG+SGYFERSL+AYGREG+ CRRCGA++RRE FMNRSS+YCPRCQ R
Sbjct  232  NVNGQSGYFERSLNAYGREGQPCRRCGAIMRRESFMNRSSYYCPRCQRR  280


>gi|262202010|ref|YP_003273218.1| formamidopyrimidine-DNA glycosylase [Gordonia bronchialis DSM 
43247]
 gi|262085357|gb|ACY21325.1| formamidopyrimidine-DNA glycosylase [Gordonia bronchialis DSM 
43247]
Length=295

 Score =  339 bits (870),  Expect = 2e-91, Method: Compositional matrix adjust.
 Identities = 176/294 (60%), Positives = 206/294 (71%), Gaps = 12/294 (4%)

Query  1    MPELPEVEVVRRGLQAHVTGRTITEVRVHHPRAVRRHDAGPADLTARLRGARINGTDRRG  60
            MPELPEVE VRRGL  H+ GRTI +V V HPRA RRH  G  DL  RLR   + G  RRG
Sbjct  1    MPELPEVETVRRGLADHLVGRTIRKVEVLHPRAARRHVGGDLDLIGRLRNKSVTGVRRRG  60

Query  61   KYLWLTLNTAGVHRPTDTALVVHLGMSGQMLLG--AVPCAAHVRISALLDDGTVLSFADQ  118
            KYLWL +  A        A+VVHLGMSGQML+     P   H+RI A LDDG  L F DQ
Sbjct  61   KYLWLDVADA----RDRAAVVVHLGMSGQMLIARAGAPDHTHLRIRASLDDGNELRFVDQ  116

Query  119  RTFGGWLLADL------VTVDGSVVPVPVAHLARDPLDPRFDCDAVVKVLRRKHSELKRQ  172
            RTFGGW + D       V    S++P  VAH+ARDP DP FD +A V  +R KHSE+KR 
Sbjct  117  RTFGGWHVDDYAEPEDAVAQSSSLLPTSVAHIARDPFDPDFDAEATVSRIRTKHSEIKRV  176

Query  173  LLDQRVVSGIGNIYADEALWRAKVNGAHVAATLRCRRLGAVLHAAADVMREALAKGGTSF  232
            LLDQ V+SG+GNIYADEALWRA++ G  VA  +   +L  +L A +DVM EALA GGTSF
Sbjct  177  LLDQTVISGVGNIYADEALWRARLYGGRVADGISRPKLRELLTAVSDVMGEALAVGGTSF  236

Query  233  DSLYVNVNGESGYFERSLDAYGREGENCRRCGAVIRRERFMNRSSFYCPRCQPR  286
            D+LYVNVNG+SGYFERSL+AYGR G+ CRRCG ++RRE FMNRSS++CPRCQ R
Sbjct  237  DALYVNVNGQSGYFERSLNAYGRAGQPCRRCGQMMRRESFMNRSSYFCPRCQRR  290


>gi|333920820|ref|YP_004494401.1| fomramidopyrimidine-DNA glycosylase [Amycolicicoccus subflavus 
DQS3-9A1]
 gi|333483041|gb|AEF41601.1| Formamidopyrimidine-DNA glycosylase [Amycolicicoccus subflavus 
DQS3-9A1]
Length=292

 Score =  336 bits (861),  Expect = 3e-90, Method: Compositional matrix adjust.
 Identities = 174/290 (60%), Positives = 205/290 (71%), Gaps = 7/290 (2%)

Query  1    MPELPEVEVVRRGLQAHVTGRTITEVRVHHPRAVRRHDAGPADLTARLRGARINGTDRRG  60
            MPELPEVEVVRRGL++H   + I  V V HPRAVRRH AGPADL  RL G   +G  RRG
Sbjct  1    MPELPEVEVVRRGLESHALRQQIESVEVRHPRAVRRHAAGPADLAGRLAGRAFSGAFRRG  60

Query  61   KYLWLTLNTAGVHRPTDTALVVHLGMSGQMLLGAV--PCAAHVRISALLDDGTVLSFADQ  118
            KYLWLTL         D+ LV HLGMSGQML+ A   P   H RI   LD GT L F DQ
Sbjct  61   KYLWLTLAEKNPDEAADSVLV-HLGMSGQMLVQAADAPMEPHARIVVTLDGGTHLRFVDQ  119

Query  119  RTFGGWLLADLVTV----DGSVVPVPVAHLARDPLDPRFDCDAVVKVLRRKHSELKRQLL  174
            RTFGGWL+A LV       G ++P P+ H+ARDPLDP FD  AV++V+RRK SE+KR LL
Sbjct  120  RTFGGWLVAPLVPAVPDSAGELLPQPIVHIARDPLDPLFDERAVIEVIRRKPSEIKRILL  179

Query  175  DQRVVSGIGNIYADEALWRAKVNGAHVAATLRCRRLGAVLHAAADVMREALAKGGTSFDS  234
            DQ V+SG+GNIYADEALWRA ++G   A +L   ++  +L AA +VM EALA+GGTSFD+
Sbjct  180  DQSVISGVGNIYADEALWRAGIHGNRSARSLSRAKIRTILFAAREVMIEALAQGGTSFDA  239

Query  235  LYVNVNGESGYFERSLDAYGREGENCRRCGAVIRRERFMNRSSFYCPRCQ  284
            LYVNVNG+SG+F+RSL  YG EG  C RCG  I RE+F NRSS +CP CQ
Sbjct  240  LYVNVNGQSGFFDRSLRVYGLEGHPCERCGTPIVREKFTNRSSHFCPICQ  289


>gi|300783720|ref|YP_003764011.1| formamidopyrimidine-DNA glycosylase [Amycolatopsis mediterranei 
U32]
 gi|299793234|gb|ADJ43609.1| formamidopyrimidine-DNA glycosylase [Amycolatopsis mediterranei 
U32]
 gi|340525110|gb|AEK40315.1| formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA 
glycosylase [Amycolatopsis mediterranei S699]
Length=289

 Score =  333 bits (854),  Expect = 2e-89, Method: Compositional matrix adjust.
 Identities = 174/292 (60%), Positives = 201/292 (69%), Gaps = 11/292 (3%)

Query  1    MPELPEVEVVRRGLQAHVTGRTITEVRVHHPRAVRRHDAGPADLTARLRGARINGTDRRG  60
            MPELPEVEVVR GLQ HV GRTI E  V HPRA+RRH  G  D T RL G R+    RRG
Sbjct  1    MPELPEVEVVRLGLQVHVAGRTIREAEVLHPRAIRRHALGAEDFTQRLAGTRVEAARRRG  60

Query  61   KYLWLTLNTAGVHRPTDTALVVHLGMSGQMLLG--AVPCAAHVRISA-LLDDGTVLSFAD  117
            KYLWL L+          AL+ HLGMSGQML+     P   H+R+     DDG  L F D
Sbjct  61   KYLWLELSDK-------EALLAHLGMSGQMLVQPEGAPDEKHLRVRLRFEDDGPELRFVD  113

Query  118  QRTFGGWLLADLVTVDGSVV-PVPVAHLARDPLDPRFDCDAVVKVLRRKHSELKRQLLDQ  176
            QRTFGG  L DL  +   V+ P  +AH+ARDP+DP FD DA V+ LR + +E+KR LLDQ
Sbjct  114  QRTFGGLALDDLSDIGSEVLLPDTIAHIARDPMDPEFDLDAAVRALRSRRTEVKRALLDQ  173

Query  177  RVVSGIGNIYADEALWRAKVNGAHVAATLRCRRLGAVLHAAADVMREALAKGGTSFDSLY  236
             +VSGIGNIYADEALWRA+++ A     L   +   +L AA+DVM  AL  GGTSFD+LY
Sbjct  174  TLVSGIGNIYADEALWRARLHWARPTEKLTMAKGRELLSAASDVMNAALGAGGTSFDALY  233

Query  237  VNVNGESGYFERSLDAYGREGENCRRCGAVIRRERFMNRSSFYCPRCQPRPR  288
            VNVNG+SGYF+RSLDAYG+EG  C RCG  IRRE FMNRSSF CPRCQPRPR
Sbjct  234  VNVNGQSGYFDRSLDAYGQEGMPCHRCGTAIRREPFMNRSSFSCPRCQPRPR  285


>gi|256379956|ref|YP_003103616.1| formamidopyrimidine-DNA glycosylase [Actinosynnema mirum DSM 
43827]
 gi|255924259|gb|ACU39770.1| formamidopyrimidine-DNA glycosylase [Actinosynnema mirum DSM 
43827]
Length=291

 Score =  327 bits (838),  Expect = 1e-87, Method: Compositional matrix adjust.
 Identities = 166/291 (58%), Positives = 203/291 (70%), Gaps = 10/291 (3%)

Query  1    MPELPEVEVVRRGLQAHVTGRTITEVRVHHPRAVRRHDAGPADLTARLRGARINGTDRRG  60
            MPELPEVEVVRRGL  HVTGRT+  V V H RA+RRH  G AD   RL G R++   RRG
Sbjct  1    MPELPEVEVVRRGLHEHVTGRTVASVEVLHARAIRRHLPGAADFAVRLTGQRMDAARRRG  60

Query  61   KYLWLTLNTAGVHRPTDTALVVHLGMSGQMLLGAV--PCAAHVRISALL-DDGTVLSFAD  117
            KYLW+ L+          A++ HLGMSGQML+  V  P   H+R+  +  DDG  L F D
Sbjct  61   KYLWVDLSGG-------EAVLAHLGMSGQMLVQPVGAPDEKHLRVRVVFEDDGPELRFVD  113

Query  118  QRTFGGWLLADLVTVDGSVVPVPVAHLARDPLDPRFDCDAVVKVLRRKHSELKRQLLDQR  177
            QRTFGG  L +LV VDG+ +P  V+H+ARDP+DP FD DA V+ LR + +++KR LLDQ 
Sbjct  114  QRTFGGLALDELVEVDGTWLPRQVSHIARDPMDPEFDADAAVRALRSRKTDVKRALLDQT  173

Query  178  VVSGIGNIYADEALWRAKVNGAHVAATLRCRRLGAVLHAAADVMREALAKGGTSFDSLYV  237
            +VSG+GNIYADE+LWRA+++G    A L   +   +L  A  VM EAL +GGTSFD+LYV
Sbjct  174  LVSGVGNIYADESLWRARLHGLRPTAKLTTAKTAELLGHATQVMLEALGQGGTSFDALYV  233

Query  238  NVNGESGYFERSLDAYGREGENCRRCGAVIRRERFMNRSSFYCPRCQPRPR  288
            NVNG+SGYF+RSL  YG+E   C RCG  I RE FMNRSS+ CPRCQPRPR
Sbjct  234  NVNGQSGYFDRSLAVYGQEDRPCARCGTAIVREPFMNRSSYSCPRCQPRPR  284


>gi|302525052|ref|ZP_07277394.1| formamidopyrimidine-DNA glycosylase [Streptomyces sp. AA4]
 gi|302433947|gb|EFL05763.1| formamidopyrimidine-DNA glycosylase [Streptomyces sp. AA4]
Length=286

 Score =  327 bits (837),  Expect = 2e-87, Method: Compositional matrix adjust.
 Identities = 170/291 (59%), Positives = 202/291 (70%), Gaps = 10/291 (3%)

Query  1    MPELPEVEVVRRGLQAHVTGRTITEVRVHHPRAVRRHDAGPADLTARLRGARINGTDRRG  60
            MPELPEVE VR GL+AHV GRT+  V V H RA+RRH  G AD T RL G  I    RRG
Sbjct  1    MPELPEVETVRAGLEAHVAGRTVRAVEVLHDRAIRRHAQGAADFTGRLAGVAIEAARRRG  60

Query  61   KYLWLTLNTAGVHRPTDTALVVHLGMSGQMLLG--AVPCAAHVRISA-LLDDGTVLSFAD  117
            KYLWL L+          A++ HLGMSGQML+     P   H+R+     D G  L F D
Sbjct  61   KYLWLELSDG-------EAVLAHLGMSGQMLVQPEGAPDEKHLRVRVRFADGGPELRFVD  113

Query  118  QRTFGGWLLADLVTVDGSVVPVPVAHLARDPLDPRFDCDAVVKVLRRKHSELKRQLLDQR  177
            QRTFGG  L +LV VDG  +P  +AH+ARDP+DP+FD +A V+ LR + +E+KR LLDQ 
Sbjct  114  QRTFGGLALDELVVVDGDSLPGTIAHIARDPMDPKFDPEAAVRALRSRRTEVKRALLDQT  173

Query  178  VVSGIGNIYADEALWRAKVNGAHVAATLRCRRLGAVLHAAADVMREALAKGGTSFDSLYV  237
            +VSG+GNIYADEALWR+K++ +     L   +   +L AA+DVM  AL  GGTSFD+LYV
Sbjct  174  LVSGVGNIYADEALWRSKLHWSRPTEKLTAAQGRTLLSAASDVMSAALLAGGTSFDALYV  233

Query  238  NVNGESGYFERSLDAYGREGENCRRCGAVIRRERFMNRSSFYCPRCQPRPR  288
            NVNGESGYFERSLDAYG+EG  CRRCG+ IRRE FMNRSSF CPRCQ R R
Sbjct  234  NVNGESGYFERSLDAYGQEGLPCRRCGSPIRREPFMNRSSFSCPRCQRRAR  284


>gi|331698523|ref|YP_004334762.1| formamidopyrimidine-DNA glycosylase [Pseudonocardia dioxanivorans 
CB1190]
 gi|326953212|gb|AEA26909.1| Formamidopyrimidine-DNA glycosylase [Pseudonocardia dioxanivorans 
CB1190]
Length=298

 Score =  321 bits (823),  Expect = 7e-86, Method: Compositional matrix adjust.
 Identities = 175/295 (60%), Positives = 200/295 (68%), Gaps = 6/295 (2%)

Query  1    MPELPEVEVVRRGLQAHVTGRTITEVRVHHPRAVRRHDAGPADLTARLRGARINGTDRRG  60
            MPELPEVEVVRRGL  HV GR I  V V HPRA+RRH AG AD T RL G  +    RRG
Sbjct  1    MPELPEVEVVRRGLADHVAGRRIATVTVAHPRAIRRHAAGAADFTGRLAGRLVGAVRRRG  60

Query  61   KYLWLTLNTAG--VHRPTDTALVVHLGMSGQMLLG--AVPCAAHVRISALLDD-GTVLSF  115
            KYLWL L  A     +P D A++ HLGMSGQML+     P   H+R+    DD G  L F
Sbjct  61   KYLWLELADAAQDAPQPGDDAVLAHLGMSGQMLVADHGKPDEKHLRVRVTFDDDGPELRF  120

Query  116  ADQRTFGGWLLADLV-TVDGSVVPVPVAHLARDPLDPRFDCDAVVKVLRRKHSELKRQLL  174
             DQRTFGG     L     G ++P PVAH+ARDP+DP F  D  V  +RR+ + LKR LL
Sbjct  121  VDQRTFGGLSAHPLAPAAGGGLLPAPVAHIARDPMDPAFVLDDAVAGIRRRRTGLKRALL  180

Query  175  DQRVVSGIGNIYADEALWRAKVNGAHVAATLRCRRLGAVLHAAADVMREALAKGGTSFDS  234
            DQ VVSGIGNIYADEALWRA+++ A    +L   +  AVL AAA+VM EALA+GGTSFD+
Sbjct  181  DQTVVSGIGNIYADEALWRARLHWARPTESLTRAQGRAVLTAAAEVMDEALAQGGTSFDA  240

Query  235  LYVNVNGESGYFERSLDAYGREGENCRRCGAVIRRERFMNRSSFYCPRCQPRPRK  289
            LYVNVNG SGYF+RSL  YG+    C RCG  IRRE FMNRSSF CPRCQPRPR 
Sbjct  241  LYVNVNGASGYFDRSLAVYGQTDRACPRCGTPIRREAFMNRSSFSCPRCQPRPRN  295


>gi|134102536|ref|YP_001108197.1| formamidopyrimidine-DNA glycosylase [Saccharopolyspora erythraea 
NRRL 2338]
 gi|291007097|ref|ZP_06565070.1| formamidopyrimidine-DNA glycosylase [Saccharopolyspora erythraea 
NRRL 2338]
 gi|166198746|sp|A4FMJ7.1|FPG_SACEN RecName: Full=Formamidopyrimidine-DNA glycosylase; Short=Fapy-DNA 
glycosylase; AltName: Full=DNA-(apurinic or apyrimidinic 
site) lyase mutM; Short=AP lyase mutM
 gi|133915159|emb|CAM05272.1| formamidopyrimidine-DNA glycosylase [Saccharopolyspora erythraea 
NRRL 2338]
Length=295

 Score =  320 bits (820),  Expect = 2e-85, Method: Compositional matrix adjust.
 Identities = 166/292 (57%), Positives = 200/292 (69%), Gaps = 3/292 (1%)

Query  1    MPELPEVEVVRRGLQAHVTGRTITEVRVHHPRAVRRHDAGPADLTARLRGARINGTDRRG  60
            MPELPEVEVVRRG+ AHV GRT++EV V HPR+VRRH  GP D   RL G  +    RRG
Sbjct  1    MPELPEVEVVRRGVAAHVVGRTVSEVEVLHPRSVRRHVPGPDDFATRLAGRCLTAARRRG  60

Query  61   KYLWLTLNTAGVHRPTDTALVVHLGMSGQMLL--GAVPCAAHVRISALLDDG-TVLSFAD  117
            KY+WL L           A++ HLGMSGQ+L+     P   H+R+    DDG   L F D
Sbjct  61   KYMWLELGGGPEEVDAGEAVLAHLGMSGQLLVQPDEAPDETHLRVRFRFDDGGPQLRFVD  120

Query  118  QRTFGGWLLADLVTVDGSVVPVPVAHLARDPLDPRFDCDAVVKVLRRKHSELKRQLLDQR  177
            QRTFGG  L +LV+VDG  VP PVAH+A DPL+P FD +A V  +R++ + +KR LLDQ 
Sbjct  121  QRTFGGLSLTELVSVDGVAVPEPVAHIAPDPLEPVFDLEAAVARMRKRRTGVKRALLDQT  180

Query  178  VVSGIGNIYADEALWRAKVNGAHVAATLRCRRLGAVLHAAADVMREALAKGGTSFDSLYV  237
            +VSGIGNIYADEALWRAK++ A   A L   +   +L AA +VM+ AL  GGTSFD LYV
Sbjct  181  LVSGIGNIYADEALWRAKLHWARPTANLTRPQARTLLVAAVEVMQAALTAGGTSFDDLYV  240

Query  238  NVNGESGYFERSLDAYGREGENCRRCGAVIRRERFMNRSSFYCPRCQPRPRK  289
            NVNGESGYF+RSL  YG+ G  C RCG  +RR+ FMNRSS+ CPRCQP PR 
Sbjct  241  NVNGESGYFDRSLAVYGQAGLPCPRCGTPVRRDAFMNRSSYSCPRCQPTPRN  292


>gi|257055002|ref|YP_003132834.1| formamidopyrimidine-DNA glycosylase [Saccharomonospora viridis 
DSM 43017]
 gi|256584874|gb|ACU96007.1| DNA-(apurinic or apyrimidinic site) lyase /Formamidopyrimidine-DNA 
glycosylase [Saccharomonospora viridis DSM 43017]
Length=287

 Score =  320 bits (819),  Expect = 2e-85, Method: Compositional matrix adjust.
 Identities = 175/292 (60%), Positives = 204/292 (70%), Gaps = 10/292 (3%)

Query  1    MPELPEVEVVRRGLQAHVTGRTITEVRVHHPRAVRRHDAGPADLTARLRGARINGTDRRG  60
            MPELPEVEVVR GL+ HV GR ++ V V HPRA+RRH  G AD   RL GA+I    RRG
Sbjct  1    MPELPEVEVVRAGLEKHVLGRIVSSVEVLHPRAIRRHVLGEADFVGRLVGAKITAVCRRG  60

Query  61   KYLWLTLNTAGVHRPTDTALVVHLGMSGQMLLG--AVPCAAHVRISA-LLDDGTVLSFAD  117
            KYLW  L          TA++ HLGMSGQML+    V    H+R+     DDG  L F D
Sbjct  61   KYLWFELADG-------TAVLAHLGMSGQMLIQPRGVVDEKHLRVRFRFSDDGPELRFVD  113

Query  118  QRTFGGWLLADLVTVDGSVVPVPVAHLARDPLDPRFDCDAVVKVLRRKHSELKRQLLDQR  177
            QRTFGG  L DLV V+G+V+P  +AH+ARDPLDP FD  A  + LR + +E+KR LLDQ 
Sbjct  114  QRTFGGLSLTDLVEVEGTVLPSAIAHIARDPLDPLFDVVATARALRTRRTEVKRALLDQT  173

Query  178  VVSGIGNIYADEALWRAKVNGAHVAATLRCRRLGAVLHAAADVMREALAKGGTSFDSLYV  237
            +VSGIGNIYADEALWR  ++ A  A  L   +   VL AAA++M EAL  GGTSFD+LYV
Sbjct  174  LVSGIGNIYADEALWRVGLHWARPADRLTATQARGVLAAAAEMMVEALRVGGTSFDALYV  233

Query  238  NVNGESGYFERSLDAYGREGENCRRCGAVIRRERFMNRSSFYCPRCQPRPRK  289
            NVNGESGYF RSLDAYGREGE CRRCG++I RE F NRSSF CPRCQP+PR 
Sbjct  234  NVNGESGYFSRSLDAYGREGEPCRRCGSLIVREAFTNRSSFSCPRCQPKPRS  285


>gi|296393288|ref|YP_003658172.1| formamidopyrimidine-DNA glycosylase [Segniliparus rotundus DSM 
44985]
 gi|296180435|gb|ADG97341.1| formamidopyrimidine-DNA glycosylase [Segniliparus rotundus DSM 
44985]
Length=283

 Score =  317 bits (811),  Expect = 2e-84, Method: Compositional matrix adjust.
 Identities = 167/290 (58%), Positives = 200/290 (69%), Gaps = 10/290 (3%)

Query  1    MPELPEVEVVRRGLQAHVTGRTITEVRVHHPRAVRRHDAGPADLTARLRGARINGTDRRG  60
            MPELPEVEVVRRGL  H+TG  I  +RV HPR+ RRH  G A L A L    +    RRG
Sbjct  1    MPELPEVEVVRRGLAEHLTGARIRALRVLHPRSARRHPGGGAFLAAALSERDVRAVRRRG  60

Query  61   KYLWLTLNTAGVHRPTDTALVVHLGMSGQMLLG--AVP-CAAHVRISALLDDGTVLSFAD  117
            KYLWL L+        + ++V+HLGMSGQ  +G   VP   AH+R+ A L DG  L F D
Sbjct  61   KYLWLVLDD-------EESVVIHLGMSGQFRVGDQGVPGNPAHLRVEADLADGRTLQFFD  113

Query  118  QRTFGGWLLADLVTVDGSVVPVPVAHLARDPLDPRFDCDAVVKVLRRKHSELKRQLLDQR  177
            QRTFGGW  A L  VDG +VP PVAH+ARDP DP+FD  AV + +R K S +KR LLDQ 
Sbjct  114  QRTFGGWEFAALQEVDGELVPAPVAHIARDPFDPKFDPAAVARRVRAKRSAIKRVLLDQT  173

Query  178  VVSGIGNIYADEALWRAKVNGAHVAATLRCRRLGAVLHAAADVMREALAKGGTSFDSLYV  237
            V+SG+GNIYADE+LWRA+++G   AA L  R+   +L A A V+ E++ +GGTSFDSLYV
Sbjct  174  VLSGVGNIYADESLWRARLHGEQPAAGLSPRKTAELLDALAVVLGESITEGGTSFDSLYV  233

Query  238  NVNGESGYFERSLDAYGREGENCRRCGAVIRRERFMNRSSFYCPRCQPRP  287
            NVNGESG F   L  YG+EG+ CRRCG+ IRRE FMNRSS YCPRCQ  P
Sbjct  234  NVNGESGRFSDWLAVYGQEGKPCRRCGSAIRREAFMNRSSHYCPRCQRLP  283


>gi|345009586|ref|YP_004811940.1| Formamidopyrimidine-DNA glycosylase [Streptomyces violaceusniger 
Tu 4113]
 gi|344035935|gb|AEM81660.1| Formamidopyrimidine-DNA glycosylase [Streptomyces violaceusniger 
Tu 4113]
Length=310

 Score =  316 bits (809),  Expect = 3e-84, Method: Compositional matrix adjust.
 Identities = 171/293 (59%), Positives = 199/293 (68%), Gaps = 10/293 (3%)

Query  1    MPELPEVEVVRRGLQAHVTGRTITEVRVHHPRAVRRHDAGPADLTARLRGARINGTDRRG  60
            MPELPEVEVVRRGL+  V+GRT+ EV+V HPRAVRRH  GP D  ARLRG R     RRG
Sbjct  1    MPELPEVEVVRRGLERWVSGRTVAEVQVLHPRAVRRHLGGPEDFAARLRGRRTGIVRRRG  60

Query  61   KYLWLTLNTAGVHRPTDTALVVHLGMSGQMLL--GAVPCAAHVRISALLDD--GTVLSFA  116
            KYLWL  +          A++ HLGMSGQ+L+     P   H+RI     D  GT L F 
Sbjct  61   KYLWLPFDDDAAA----EAVLAHLGMSGQLLVQPAEAPDEKHLRIRVRFADAAGTELRFV  116

Query  117  DQRTFGGWLLADLVTVDGSVVPVPVAHLARDPLDPRFDCDAVVKVLRRKHSELKRQLLDQ  176
            DQRTFGG  L D V  D   +P  +AH+ARDPLDP FD  A    LRR+ + +KR LLDQ
Sbjct  117  DQRTFGGLSLHDTVPGDLEGLPDAIAHIARDPLDPAFDEAAFHTALRRRRTTIKRALLDQ  176

Query  177  RVVSGIGNIYADEALWRAKVNGAHVAATLRCRRLGAVLHAAADVMREALAKGGTSFDSLY  236
             ++SG+GNIYADEALWRA+++     ATL   R   +L    +VM  ALA GGTSFDSLY
Sbjct  177  SLISGVGNIYADEALWRARLHYDRPTATLARPRAAELLGHVREVMTAALAVGGTSFDSLY  236

Query  237  VNVNGESGYFERSLDAYGREGENCRRCGAVIRRERFMNRSSFYCPRCQ--PRP  287
            VNVNGESGYFERSLDAYGRE E CRRCG  +RR  +MNRSS++CPRCQ  PRP
Sbjct  237  VNVNGESGYFERSLDAYGRENEPCRRCGTAMRRRPWMNRSSYFCPRCQRPPRP  289


>gi|326382853|ref|ZP_08204543.1| formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA 
glycosylase [Gordonia neofelifaecis NRRL B-59395]
 gi|326198443|gb|EGD55627.1| formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA 
glycosylase [Gordonia neofelifaecis NRRL B-59395]
Length=295

 Score =  315 bits (808),  Expect = 4e-84, Method: Compositional matrix adjust.
 Identities = 162/290 (56%), Positives = 200/290 (69%), Gaps = 6/290 (2%)

Query  1    MPELPEVEVVRRGLQAHVTGRTITEVRVHHPRAVRRHDAGPADLTARLRGARINGTDRRG  60
            +PELPEVE +R GL AH++GR++ +V V HPRA RRH  GP DL+ RLRG R  G +RRG
Sbjct  3    VPELPEVETIRLGLSAHLSGRSVRDVEVLHPRAARRHVGGPIDLSNRLRGKRFEGAERRG  62

Query  61   KYLWLTLNTAGVHRPTDTALVVHLGMSGQMLLG--AVPCAAHVRISALLDDGTVLSFADQ  118
            KY+WL  + +      + A+VVHLGMSGQML+         H+RI   LDDG  L F DQ
Sbjct  63   KYMWLLASDSA----DEVAVVVHLGMSGQMLIAEQGAEDPVHLRIRVPLDDGHELRFVDQ  118

Query  119  RTFGGWLLADLVTVDGSVVPVPVAHLARDPLDPRFDCDAVVKVLRRKHSELKRQLLDQRV  178
            RTFGGW L DLV      +P  VAH+A DP +  FD  AV+  LRR+ +E+KR +LDQ V
Sbjct  119  RTFGGWHLDDLVDTGPRRLPESVAHIAPDPFEDAFDRGAVIDSLRRRDTEIKRAILDQTV  178

Query  179  VSGIGNIYADEALWRAKVNGAHVAATLRCRRLGAVLHAAADVMREALAKGGTSFDSLYVN  238
            +SG+GNIYADE+LWRA+++G      +   RLG ++  A  VM EA+  GGTSFD LYVN
Sbjct  179  ISGVGNIYADESLWRAELHGRRRTRGIPRARLGDLVDHATQVMGEAIKVGGTSFDDLYVN  238

Query  239  VNGESGYFERSLDAYGREGENCRRCGAVIRRERFMNRSSFYCPRCQPRPR  288
            VNG+SGYFERSL+AYGREG  CRRC   + RE FMNRSSF+CP CQ  PR
Sbjct  239  VNGQSGYFERSLNAYGREGLLCRRCETPMVREAFMNRSSFFCPTCQRVPR  288


>gi|294815351|ref|ZP_06773994.1| DNA glycosylase [Streptomyces clavuligerus ATCC 27064]
 gi|326443705|ref|ZP_08218439.1| formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA 
glycosylase [Streptomyces clavuligerus ATCC 27064]
 gi|294327950|gb|EFG09593.1| DNA glycosylase [Streptomyces clavuligerus ATCC 27064]
Length=289

 Score =  315 bits (807),  Expect = 5e-84, Method: Compositional matrix adjust.
 Identities = 176/293 (61%), Positives = 205/293 (70%), Gaps = 14/293 (4%)

Query  1    MPELPEVEVVRRGLQAHVTGRTITEVRVHHPRAVRRHDAGPADLTARLRGARINGTDRRG  60
            MPELPEVEVVRRGLQ  V+GRTI EVRV HPRAVRRH AG  D  ARL+G  +    RRG
Sbjct  1    MPELPEVEVVRRGLQRWVSGRTIAEVRVLHPRAVRRHIAGAGDFAARLKGHSVGIARRRG  60

Query  61   KYLWLTLNTAGVHRPTDTALVVHLGMSGQMLLGAVPCA--AHVRISALLDD--GTVLSFA  116
            KYLWL L        TD++++ HLGMSGQ+L+     A   H+RI    DD  GT L F 
Sbjct  61   KYLWLPLAD------TDSSVLGHLGMSGQLLVQPEDAADEKHLRIRISFDDSLGTELRFV  114

Query  117  DQRTFGGWLLADLVTVDGSVVPVPVAHLARDPLDPRFDCDAVVKVLRRKHSELKRQLLDQ  176
            DQRTFGG  L D  T DG  +P  +AH+ARDPLDP FD DA    LR K + +KR LLDQ
Sbjct  115  DQRTFGGLSLHD-NTPDG--LPDVIAHIARDPLDPAFDDDAFHAALRAKRTTVKRALLDQ  171

Query  177  RVVSGIGNIYADEALWRAKVNGAHVAATLRCRRLGAVLHAAADVMREALAKGGTSFDSLY  236
             ++SG+GNIYADEALWRA+++     A+L   R   +L    DVM  ALA GGTSFDSLY
Sbjct  172  SLISGVGNIYADEALWRARLHYERPTASLTRPRSAELLGHIRDVMNAALAAGGTSFDSLY  231

Query  237  VNVNGESGYFERSLDAYGREGENCRRCGAVIRRERFMNRSSFYCPRCQPRPRK  289
            VNVNGESGYF+RSLDAYGREGE CRRCG  +RR  +MNRSS++CPRCQ RP +
Sbjct  232  VNVNGESGYFDRSLDAYGREGEPCRRCGTPMRRRPWMNRSSYFCPRCQ-RPSR  283


>gi|239991060|ref|ZP_04711724.1| formamidopyrimidine-DNA glycosylase [Streptomyces roseosporus 
NRRL 11379]
 gi|291448062|ref|ZP_06587452.1| formamidopyrimidine-DNA glycosylase lyase mutM [Streptomyces 
roseosporus NRRL 15998]
 gi|291351009|gb|EFE77913.1| formamidopyrimidine-DNA glycosylase lyase mutM [Streptomyces 
roseosporus NRRL 15998]
Length=286

 Score =  315 bits (807),  Expect = 5e-84, Method: Compositional matrix adjust.
 Identities = 173/292 (60%), Positives = 203/292 (70%), Gaps = 13/292 (4%)

Query  1    MPELPEVEVVRRGLQAHVTGRTITEVRVHHPRAVRRHDAGPADLTARLRGARINGTDRRG  60
            MPELPEVEVVRRGL+  V+GRT+TEV V HPR+VRRH AG  D  ARLRGAR+    RRG
Sbjct  1    MPELPEVEVVRRGLERWVSGRTVTEVEVLHPRSVRRHLAGGVDFAARLRGARLGAAMRRG  60

Query  61   KYLWLTLNTAGVHRPTDTALVVHLGMSGQMLL--GAVPCAAHVRISALLDD--GTVLSFA  116
            KYLW+ +  A        +L+ HLGMSGQ+L+     P   H+RI    DD  GT L F 
Sbjct  61   KYLWVPIEEASA------SLLGHLGMSGQLLVQPADAPDEKHLRIRMRFDDALGTELRFV  114

Query  117  DQRTFGGWLLADLVTVDGSVVPVPVAHLARDPLDPRFDCDAVVKVLRRKHSELKRQLLDQ  176
            DQRTFGG  L D  T DG  +P  +AH+ARDPLDP FD  A    LR + + +KR LLDQ
Sbjct  115  DQRTFGGLSLHD-NTPDG--LPDTIAHIARDPLDPLFDDAAFHTALRLRRTTVKRALLDQ  171

Query  177  RVVSGIGNIYADEALWRAKVNGAHVAATLRCRRLGAVLHAAADVMREALAKGGTSFDSLY  236
             ++SG+GNIYADEALWRAK++     ATL   +   +L  A DVM  ALA+GGTSFDSLY
Sbjct  172  SLISGVGNIYADEALWRAKLHYDRPTATLTRPKSAELLGHARDVMNAALAQGGTSFDSLY  231

Query  237  VNVNGESGYFERSLDAYGREGENCRRCGAVIRRERFMNRSSFYCPRCQPRPR  288
            VNVNGESGYF+RSLDAYGREGE C RC   +RR  +MNRSS+YCPRCQ  PR
Sbjct  232  VNVNGESGYFDRSLDAYGREGEPCNRCSTPMRRRAWMNRSSYYCPRCQRPPR  283


>gi|311742942|ref|ZP_07716750.1| DNA-formamidopyrimidine glycosylase [Aeromicrobium marinum DSM 
15272]
 gi|311313622|gb|EFQ83531.1| DNA-formamidopyrimidine glycosylase [Aeromicrobium marinum DSM 
15272]
Length=284

 Score =  312 bits (800),  Expect = 3e-83, Method: Compositional matrix adjust.
 Identities = 167/291 (58%), Positives = 200/291 (69%), Gaps = 12/291 (4%)

Query  1    MPELPEVEVVRRGLQAHVTGRTITEVRVHHPRAVRRHDAGPADLTARLRGARINGTDRRG  60
            MPELPEVEVVR GL  HV GRT+++VRV   R++RRH  GP D   RLRG  +    RRG
Sbjct  1    MPELPEVEVVRLGLVDHVVGRTVSDVRVLDARSLRRHLPGPVDFADRLRGRTVVDACRRG  60

Query  61   KYLWLTLNTAGVHRPTDTALVVHLGMSGQMLLGA--VPCAAHVRISALLDDGTVLSFADQ  118
            KYLWL L+         +AL  HLGMSGQML+G    P   H+R+   LDDGT L F DQ
Sbjct  61   KYLWLPLDDG-------SALTAHLGMSGQMLIGTEQTPDPRHLRVGLDLDDGTRLHFVDQ  113

Query  119  RTFGGWLLADLVTVDGSVVPVPVAHLARDPLDPRFDCDAVVKVLRRKHSELKRQLLDQRV  178
            R FGG  ++D V+ DG  VP  +AH+ARDPLDP FD +     LRR+ + +KR LLDQ +
Sbjct  114  RIFGGLAVSDQVS-DG--VPAAMAHIARDPLDPAFDAEEFSARLRRRQTGVKRALLDQTL  170

Query  179  VSGIGNIYADEALWRAKVNGAHVAATLRCRRLGAVLHAAADVMREALAKGGTSFDSLYVN  238
            VSGIGNIYADEALWR  ++ A     LR   + A++    DVMR AL +GGTSFD+LYVN
Sbjct  171  VSGIGNIYADEALWRVPLHYARNTRHLRRAEIDALVEHVTDVMRAALEQGGTSFDALYVN  230

Query  239  VNGESGYFERSLDAYGREGENCRRCGAVIRRERFMNRSSFYCPRCQPRPRK  289
            VNG+SGYF+RSL AYGREGE C RC   +RR  FMNRSSF+CP CQPRPR+
Sbjct  231  VNGQSGYFDRSLHAYGREGEPCDRCTTPMRRSPFMNRSSFWCPACQPRPRQ  281


>gi|182435700|ref|YP_001823419.1| formamidopyrimidine-DNA glycosylase [Streptomyces griseus subsp. 
griseus NBRC 13350]
 gi|238689009|sp|B1VYY1.1|FPG_STRGG RecName: Full=Formamidopyrimidine-DNA glycosylase; Short=Fapy-DNA 
glycosylase; AltName: Full=DNA-(apurinic or apyrimidinic 
site) lyase mutM; Short=AP lyase mutM
 gi|178464216|dbj|BAG18736.1| putative formamidopyrimidine-DNA glycosylase [Streptomyces griseus 
subsp. griseus NBRC 13350]
Length=286

 Score =  311 bits (798),  Expect = 6e-83, Method: Compositional matrix adjust.
 Identities = 172/292 (59%), Positives = 202/292 (70%), Gaps = 13/292 (4%)

Query  1    MPELPEVEVVRRGLQAHVTGRTITEVRVHHPRAVRRHDAGPADLTARLRGARINGTDRRG  60
            MPELPEVEVVRRGL+  V+GRT++EV V HPRAVRRH AG  D  ARL GAR     RRG
Sbjct  1    MPELPEVEVVRRGLERWVSGRTVSEVEVLHPRAVRRHLAGGVDFAARLAGARFGAAMRRG  60

Query  61   KYLWLTLNTAGVHRPTDTALVVHLGMSGQMLL--GAVPCAAHVRISALLDD--GTVLSFA  116
            KYLW+ ++ A        +L+ HLGMSGQ+L+     P   H+RI    DD  GT L F 
Sbjct  61   KYLWVPIDEASA------SLLGHLGMSGQLLVRPADAPDEKHLRIRMRFDDALGTELRFV  114

Query  117  DQRTFGGWLLADLVTVDGSVVPVPVAHLARDPLDPRFDCDAVVKVLRRKHSELKRQLLDQ  176
            DQRTFGG L     T DG  +P  +AH+ARDPLDP FD  A    LR + + +KR LLDQ
Sbjct  115  DQRTFGG-LSLHANTPDG--LPETIAHIARDPLDPLFDDAAFHTALRLRRTTVKRALLDQ  171

Query  177  RVVSGIGNIYADEALWRAKVNGAHVAATLRCRRLGAVLHAAADVMREALAKGGTSFDSLY  236
             ++SG+GNIYADEALWRA+++     ATL   R   +L  A DVM  ALA+GGTSFDSLY
Sbjct  172  SLISGVGNIYADEALWRARLHYDRPTATLTRPRSAELLGHARDVMNAALAQGGTSFDSLY  231

Query  237  VNVNGESGYFERSLDAYGREGENCRRCGAVIRRERFMNRSSFYCPRCQPRPR  288
            VNVNGESGYF+RSLDAYGREGE C RCG  +RR  +MNRSS+YCPRCQ  PR
Sbjct  232  VNVNGESGYFDRSLDAYGREGEPCHRCGTPMRRRAWMNRSSYYCPRCQRPPR  283


>gi|326776325|ref|ZP_08235590.1| Formamidopyrimidine-DNA glycosylase [Streptomyces cf. griseus 
XylebKG-1]
 gi|326656658|gb|EGE41504.1| Formamidopyrimidine-DNA glycosylase [Streptomyces griseus XylebKG-1]
Length=286

 Score =  311 bits (797),  Expect = 8e-83, Method: Compositional matrix adjust.
 Identities = 172/292 (59%), Positives = 202/292 (70%), Gaps = 13/292 (4%)

Query  1    MPELPEVEVVRRGLQAHVTGRTITEVRVHHPRAVRRHDAGPADLTARLRGARINGTDRRG  60
            MPELPEVEVVRRGL+  V+GRT++EV V HPRAVRRH AG  D  ARL GAR     RRG
Sbjct  1    MPELPEVEVVRRGLERWVSGRTVSEVEVLHPRAVRRHLAGGVDFAARLAGARFGAAMRRG  60

Query  61   KYLWLTLNTAGVHRPTDTALVVHLGMSGQMLL--GAVPCAAHVRISALLDD--GTVLSFA  116
            KYLW+ ++ A        +L+ HLGMSGQ+L+     P   H+RI    DD  GT L F 
Sbjct  61   KYLWVPIDEASA------SLLGHLGMSGQLLVRPADAPDEKHLRIRMRFDDALGTELRFV  114

Query  117  DQRTFGGWLLADLVTVDGSVVPVPVAHLARDPLDPRFDCDAVVKVLRRKHSELKRQLLDQ  176
            DQRTFGG L     T DG  +P  +AH+ARDPLDP FD  A    LR + + +KR LLDQ
Sbjct  115  DQRTFGG-LSLHANTPDG--LPDTIAHIARDPLDPLFDDAAFHTALRLRRTTVKRALLDQ  171

Query  177  RVVSGIGNIYADEALWRAKVNGAHVAATLRCRRLGAVLHAAADVMREALAKGGTSFDSLY  236
             ++SG+GNIYADEALWRA+++     ATL   R   +L  A DVM  ALA+GGTSFDSLY
Sbjct  172  SLISGVGNIYADEALWRARLHYDRPTATLTRPRSAELLGHARDVMNAALAQGGTSFDSLY  231

Query  237  VNVNGESGYFERSLDAYGREGENCRRCGAVIRRERFMNRSSFYCPRCQPRPR  288
            VNVNGESGYF+RSLDAYGREGE C RCG  +RR  +MNRSS+YCPRCQ  PR
Sbjct  232  VNVNGESGYFDRSLDAYGREGEPCHRCGTPMRRRAWMNRSSYYCPRCQRPPR  283


>gi|302554408|ref|ZP_07306750.1| formamidopyrimidine-DNA glycosylase [Streptomyces viridochromogenes 
DSM 40736]
 gi|302472026|gb|EFL35119.1| formamidopyrimidine-DNA glycosylase [Streptomyces viridochromogenes 
DSM 40736]
Length=286

 Score =  307 bits (786),  Expect = 1e-81, Method: Compositional matrix adjust.
 Identities = 171/292 (59%), Positives = 198/292 (68%), Gaps = 13/292 (4%)

Query  1    MPELPEVEVVRRGLQAHVTGRTITEVRVHHPRAVRRHDAGPADLTARLRGARINGTDRRG  60
            MPELPEVEVVRRGLQ  V  RT+ E  V HPRAVRRH AG  D   RL+G RI    RRG
Sbjct  1    MPELPEVEVVRRGLQRWVAHRTVAETEVLHPRAVRRHLAGADDFAHRLKGHRIGTPSRRG  60

Query  61   KYLWLTLNTAGVHRPTDTALVVHLGMSGQMLLG--AVPCAAHVRISALLDDG--TVLSFA  116
            KYLWL L        TD +++ HLGMSGQ+L+     P   H+RI     D   T L F 
Sbjct  61   KYLWLPLED------TDQSILAHLGMSGQLLVQPHTAPDEKHLRIRVRFTDALDTELRFV  114

Query  117  DQRTFGGWLLADLVTVDGSVVPVPVAHLARDPLDPRFDCDAVVKVLRRKHSELKRQLLDQ  176
            DQRTFGG  L D  T DG  +P  +AH+ARDPLD  FD +A  + LRRK S +KR LLDQ
Sbjct  115  DQRTFGGLSLHD-NTPDG--LPDVIAHIARDPLDEFFDDEAFHRALRRKRSTIKRALLDQ  171

Query  177  RVVSGIGNIYADEALWRAKVNGAHVAATLRCRRLGAVLHAAADVMREALAKGGTSFDSLY  236
             ++SG+GNIYADEALWRA+++     ATL   R  ++L    DVM  ALA GGTSFDSLY
Sbjct  172  SLISGVGNIYADEALWRARLHYERPTATLTRPRTLSLLGHVRDVMNAALAVGGTSFDSLY  231

Query  237  VNVNGESGYFERSLDAYGREGENCRRCGAVIRRERFMNRSSFYCPRCQPRPR  288
            VNVNGESGYF+RSLDAYGREG  CRRCG  +RR  +MNRSS+YCP+CQ  PR
Sbjct  232  VNVNGESGYFDRSLDAYGREGLPCRRCGTPMRRRPWMNRSSYYCPKCQRPPR  283


>gi|21223929|ref|NP_629708.1| formamidopyrimidine-DNA glycosylase [Streptomyces coelicolor 
A3(2)]
 gi|289768865|ref|ZP_06528243.1| formamidopyrimidine-DNA glycosylase [Streptomyces lividans TK24]
 gi|7531122|sp|Q9ZBQ6.3|FPG_STRCO RecName: Full=Formamidopyrimidine-DNA glycosylase; Short=Fapy-DNA 
glycosylase; AltName: Full=DNA-(apurinic or apyrimidinic 
site) lyase mutM; Short=AP lyase mutM
 gi|4007732|emb|CAA22416.1| formamidopyrimidine-DNA glycosylase [Streptomyces coelicolor 
A3(2)]
 gi|289699064|gb|EFD66493.1| formamidopyrimidine-DNA glycosylase [Streptomyces lividans TK24]
Length=286

 Score =  307 bits (786),  Expect = 1e-81, Method: Compositional matrix adjust.
 Identities = 168/292 (58%), Positives = 197/292 (68%), Gaps = 13/292 (4%)

Query  1    MPELPEVEVVRRGLQAHVTGRTITEVRVHHPRAVRRHDAGPADLTARLRGARINGTDRRG  60
            MPELPEVEVVRRGL+     RT+ +V V HPRAVRRH AGP D   RL+  RI    RRG
Sbjct  1    MPELPEVEVVRRGLERWAAHRTVADVEVLHPRAVRRHVAGPDDFAHRLKDHRIGTPSRRG  60

Query  61   KYLWLTLNTAGVHRPTDTALVVHLGMSGQMLLGA--VPCAAHVRISALLDD--GTVLSFA  116
            KYLWL L        TD A++ HLGMSGQ+L+     P   H+RI     D  GT L F 
Sbjct  61   KYLWLPLED------TDQAVLAHLGMSGQLLVQPHETPAEKHLRIRVRFADALGTELRFV  114

Query  117  DQRTFGGWLLADLVTVDGSVVPVPVAHLARDPLDPRFDCDAVVKVLRRKHSELKRQLLDQ  176
            DQRTFGG  L D  + DG  +P  +AH+ARDPLDP FD +A    LRRK + +KR LLDQ
Sbjct  115  DQRTFGGLSLHD-TSADG--LPDVIAHIARDPLDPLFDDEAFHHALRRKRTTIKRALLDQ  171

Query  177  RVVSGIGNIYADEALWRAKVNGAHVAATLRCRRLGAVLHAAADVMREALAKGGTSFDSLY  236
             ++SG+GNIYADEALWRA+++     ATL   R   +L    DVM  ALA GGTSFDSLY
Sbjct  172  SLISGVGNIYADEALWRARLHYERPTATLTRPRTTELLGHVRDVMNAALAVGGTSFDSLY  231

Query  237  VNVNGESGYFERSLDAYGREGENCRRCGAVIRRERFMNRSSFYCPRCQPRPR  288
            VNVNGESGYF+RSLDAYGREG  CRRC   +RR  +MNRSS++CP+CQ  PR
Sbjct  232  VNVNGESGYFDRSLDAYGREGMPCRRCATPMRRRPWMNRSSYFCPKCQRPPR  283


>gi|254392459|ref|ZP_05007639.1| formamidopyrimidine-DNA glycosylase lyase mutM [Streptomyces 
clavuligerus ATCC 27064]
 gi|197706126|gb|EDY51938.1| formamidopyrimidine-DNA glycosylase lyase mutM [Streptomyces 
clavuligerus ATCC 27064]
Length=286

 Score =  307 bits (786),  Expect = 1e-81, Method: Compositional matrix adjust.
 Identities = 172/290 (60%), Positives = 202/290 (70%), Gaps = 14/290 (4%)

Query  4    LPEVEVVRRGLQAHVTGRTITEVRVHHPRAVRRHDAGPADLTARLRGARINGTDRRGKYL  63
            +PEVEVVRRGLQ  V+GRTI EVRV HPRAVRRH AG  D  ARL+G  +    RRGKYL
Sbjct  1    MPEVEVVRRGLQRWVSGRTIAEVRVLHPRAVRRHIAGAGDFAARLKGHSVGIARRRGKYL  60

Query  64   WLTLNTAGVHRPTDTALVVHLGMSGQMLLGAVPCA--AHVRISALLDD--GTVLSFADQR  119
            WL L        TD++++ HLGMSGQ+L+     A   H+RI    DD  GT L F DQR
Sbjct  61   WLPLAD------TDSSVLGHLGMSGQLLVQPEDAADEKHLRIRISFDDSLGTELRFVDQR  114

Query  120  TFGGWLLADLVTVDGSVVPVPVAHLARDPLDPRFDCDAVVKVLRRKHSELKRQLLDQRVV  179
            TFGG  L D  T DG  +P  +AH+ARDPLDP FD DA    LR K + +KR LLDQ ++
Sbjct  115  TFGGLSLHD-NTPDG--LPDVIAHIARDPLDPAFDDDAFHAALRAKRTTVKRALLDQSLI  171

Query  180  SGIGNIYADEALWRAKVNGAHVAATLRCRRLGAVLHAAADVMREALAKGGTSFDSLYVNV  239
            SG+GNIYADEALWRA+++     A+L   R   +L    DVM  ALA GGTSFDSLYVNV
Sbjct  172  SGVGNIYADEALWRARLHYERPTASLTRPRSAELLGHIRDVMNAALAAGGTSFDSLYVNV  231

Query  240  NGESGYFERSLDAYGREGENCRRCGAVIRRERFMNRSSFYCPRCQPRPRK  289
            NGESGYF+RSLDAYGREGE CRRCG  +RR  +MNRSS++CPRCQ RP +
Sbjct  232  NGESGYFDRSLDAYGREGEPCRRCGTPMRRRPWMNRSSYFCPRCQ-RPSR  280


>gi|329936741|ref|ZP_08286448.1| formamidopyrimidine-DNA glycosylase [Streptomyces griseoaurantiacus 
M045]
 gi|329303971|gb|EGG47854.1| formamidopyrimidine-DNA glycosylase [Streptomyces griseoaurantiacus 
M045]
Length=293

 Score =  306 bits (785),  Expect = 2e-81, Method: Compositional matrix adjust.
 Identities = 168/292 (58%), Positives = 198/292 (68%), Gaps = 13/292 (4%)

Query  1    MPELPEVEVVRRGLQAHVTGRTITEVRVHHPRAVRRHDAGPADLTARLRGARINGTDRRG  60
            MPELPEVEVVRRGL   V  RT+  V V HPRAVRRH AG  +   RL G R+    RRG
Sbjct  1    MPELPEVEVVRRGLTRWVAHRTVAAVEVLHPRAVRRHLAGGENFAQRLTGHRLGAPARRG  60

Query  61   KYLWLTLNTAGVHRPTDTALVVHLGMSGQMLLGA--VPCAAHVRISALLDD--GTVLSFA  116
            KYLWL L        TD A++ HLGMSGQ+L+     P   H+RI    +D  GT L F 
Sbjct  61   KYLWLPLED------TDEAVLAHLGMSGQLLVQPHEAPTEKHLRIRVRFEDALGTELRFV  114

Query  117  DQRTFGGWLLADLVTVDGSVVPVPVAHLARDPLDPRFDCDAVVKVLRRKHSELKRQLLDQ  176
            DQRTFGG  L D  T DG  +P  +AH+ARDPLDP FD +A  + LRRK + +KR LLDQ
Sbjct  115  DQRTFGGLSLHD-TTPDG--LPDVIAHIARDPLDPLFDEEAFHRALRRKRTTVKRALLDQ  171

Query  177  RVVSGIGNIYADEALWRAKVNGAHVAATLRCRRLGAVLHAAADVMREALAKGGTSFDSLY  236
             ++SG+GNIYADEALWR++++     ATL   R   +L    DVM  ALA GGTSFDSLY
Sbjct  172  SLISGVGNIYADEALWRSRLHYERPTATLTRPRTTELLGHVRDVMNAALAVGGTSFDSLY  231

Query  237  VNVNGESGYFERSLDAYGREGENCRRCGAVIRRERFMNRSSFYCPRCQPRPR  288
            VNVNGESGYF+RSLDAYGRE   CRRCG  +RR  +MNRSS++CP+CQP PR
Sbjct  232  VNVNGESGYFDRSLDAYGREDLPCRRCGTPMRRRPWMNRSSYFCPKCQPAPR  283



Lambda     K      H
   0.324    0.138    0.425 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Effective search space used: 470845709104


  Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
    Posted date:  Sep 5, 2011  4:36 AM
  Number of letters in database: 5,219,829,388
  Number of sequences in database:  15,229,318



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40