BLASTP 2.2.25+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.



Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
           15,229,318 sequences; 5,219,829,388 total letters



Query= Rv2925c

Length=240
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

gi|15610062|ref|NP_217441.1|  ribonuclease III [Mycobacterium tub...   479    1e-133
gi|71042598|pdb|2A11|A  Chain A, Crystal Structure Of Nuclease Do...   479    1e-133
gi|240169618|ref|ZP_04748277.1|  ribonuclease III [Mycobacterium ...   416    1e-114
gi|296171390|ref|ZP_06852723.1|  ribonuclease III [Mycobacterium ...   401    4e-110
gi|254233016|ref|ZP_04926343.1|  ribonuclease III rnc (RNase III)...   394    5e-108
gi|118617606|ref|YP_905938.1|  ribonuclease III [Mycobacterium ul...   382    2e-104
gi|183981795|ref|YP_001850086.1|  ribonuclease III Rnc [Mycobacte...   382    2e-104
gi|15827877|ref|NP_302140.1|  ribonuclease III [Mycobacterium lep...   382    3e-104
gi|41409093|ref|NP_961929.1|  ribonuclease III [Mycobacterium avi...   379    2e-103
gi|336459093|gb|EGO38042.1|  ribonuclease III [Mycobacterium aviu...   378    5e-103
gi|118462414|ref|YP_882955.1|  ribonuclease III [Mycobacterium av...   377    7e-103
gi|294993977|ref|ZP_06799668.1|  ribonuclease III [Mycobacterium ...   375    3e-102
gi|254822109|ref|ZP_05227110.1|  ribonuclease III [Mycobacterium ...   370    1e-100
gi|342858221|ref|ZP_08714876.1|  ribonuclease III [Mycobacterium ...   367    9e-100
gi|118470776|ref|YP_886758.1|  ribonuclease III [Mycobacterium sm...   362    2e-98 
gi|333991297|ref|YP_004523911.1|  ribonuclease III Rnc [Mycobacte...   357    8e-97 
gi|145224771|ref|YP_001135449.1|  ribonuclease III [Mycobacterium...   356    2e-96 
gi|120403163|ref|YP_952992.1|  ribonuclease III [Mycobacterium va...   338    4e-91 
gi|108798917|ref|YP_639114.1|  ribonuclease III [Mycobacterium sp...   335    4e-90 
gi|169630337|ref|YP_001703986.1|  ribonuclease III [Mycobacterium...   325    5e-87 
gi|333920821|ref|YP_004494402.1|  ribonuclease III [Amycolicicocc...   310    1e-82 
gi|54026155|ref|YP_120397.1|  ribonuclease III [Nocardia farcinic...   300    2e-79 
gi|326382852|ref|ZP_08204542.1|  ribonuclease III [Gordonia neofe...   299    2e-79 
gi|296139284|ref|YP_003646527.1|  ribonuclease III [Tsukamurella ...   294    9e-78 
gi|312140459|ref|YP_004007795.1|  ribonuclease iii [Rhodococcus e...   293    2e-77 
gi|226365983|ref|YP_002783766.1|  ribonuclease III [Rhodococcus o...   289    2e-76 
gi|111023481|ref|YP_706453.1|  ribonuclease III [Rhodococcus jost...   289    3e-76 
gi|226305918|ref|YP_002765878.1|  ribonuclease III [Rhodococcus e...   289    3e-76 
gi|331698524|ref|YP_004334763.1|  Ribonuclease 3 [Pseudonocardia ...   288    4e-76 
gi|229491421|ref|ZP_04385245.1|  ribonuclease III [Rhodococcus er...   287    1e-75 
gi|238063283|ref|ZP_04607992.1|  ribonuclease III [Micromonospora...   285    4e-75 
gi|330466266|ref|YP_004404009.1|  ribonuclease iii [Verrucosispor...   284    7e-75 
gi|315502406|ref|YP_004081293.1|  ribonuclease III [Micromonospor...   284    7e-75 
gi|302865861|ref|YP_003834498.1|  ribonuclease III [Micromonospor...   284    7e-75 
gi|72161055|ref|YP_288712.1|  ribonuclease III [Thermobifida fusc...   281    5e-74 
gi|262202009|ref|YP_003273217.1|  ribonuclease III [Gordonia bron...   281    6e-74 
gi|325000484|ref|ZP_08121596.1|  RNAse III [Pseudonocardia sp. P1]     280    1e-73 
gi|343925329|ref|ZP_08764854.1|  ribonuclease 3 [Gordonia alkaniv...   277    1e-72 
gi|296393287|ref|YP_003658171.1|  ribonuclease III [Segniliparus ...   275    4e-72 
gi|289571114|ref|ZP_06451341.1|  ribonuclease III rnc [Mycobacter...   275    6e-72 
gi|317506412|ref|ZP_07964217.1|  ribonuclease III [Segniliparus r...   273    2e-71 
gi|311898536|dbj|BAJ30944.1|  putative ribonuclease 3 [Kitasatosp...   268    7e-70 
gi|159036823|ref|YP_001536076.1|  ribonuclease III [Salinispora a...   265    4e-69 
gi|312194940|ref|YP_004015001.1|  ribonuclease III [Frankia sp. E...   265    4e-69 
gi|145593838|ref|YP_001158135.1|  ribonuclease III [Salinispora t...   265    4e-69 
gi|288923504|ref|ZP_06417623.1|  ribonuclease III [Frankia sp. EU...   264    8e-69 
gi|300783718|ref|YP_003764009.1|  ribonuclease III [Amycolatopsis...   262    3e-68 
gi|284032688|ref|YP_003382619.1|  ribonuclease III [Kribbella fla...   262    3e-68 
gi|319948353|ref|ZP_08022497.1|  ribonuclease III [Dietzia cinnam...   261    6e-68 
gi|258652105|ref|YP_003201261.1|  ribonuclease III [Nakamurella m...   260    1e-67 


>gi|15610062|ref|NP_217441.1| ribonuclease III [Mycobacterium tuberculosis H37Rv]
 gi|15842471|ref|NP_337508.1| ribonuclease III [Mycobacterium tuberculosis CDC1551]
 gi|31794102|ref|NP_856595.1| ribonuclease III [Mycobacterium bovis AF2122/97]
 77 more sequence titles
 Length=240

 Score =  479 bits (1234),  Expect = 1e-133, Method: Compositional matrix adjust.
 Identities = 240/240 (100%), Positives = 240/240 (100%), Gaps = 0/240 (0%)

Query  1    MIRSRQPLLDALGVDLPDELLSLALTHRSYAYENGGLPTNERLEFLGDAVLGLTITDALF  60
            MIRSRQPLLDALGVDLPDELLSLALTHRSYAYENGGLPTNERLEFLGDAVLGLTITDALF
Sbjct  1    MIRSRQPLLDALGVDLPDELLSLALTHRSYAYENGGLPTNERLEFLGDAVLGLTITDALF  60

Query  61   HRHPDRSEGDLAKLRASVVNTQALADVARRLCAEGLGVHVLLGRGEANTGGADKSSILAD  120
            HRHPDRSEGDLAKLRASVVNTQALADVARRLCAEGLGVHVLLGRGEANTGGADKSSILAD
Sbjct  61   HRHPDRSEGDLAKLRASVVNTQALADVARRLCAEGLGVHVLLGRGEANTGGADKSSILAD  120

Query  121  GMESLLGAIYLQHGMEKAREVILRLFGPLLDAAPTLGAGLDWKTSLQELTAARGLGAPSY  180
            GMESLLGAIYLQHGMEKAREVILRLFGPLLDAAPTLGAGLDWKTSLQELTAARGLGAPSY
Sbjct  121  GMESLLGAIYLQHGMEKAREVILRLFGPLLDAAPTLGAGLDWKTSLQELTAARGLGAPSY  180

Query  181  LVTSTGPDHDKEFTAVVVVMDSEYGSGVGRSKKEAEQKAAAAAWKALEVLDNAMPGKTSA  240
            LVTSTGPDHDKEFTAVVVVMDSEYGSGVGRSKKEAEQKAAAAAWKALEVLDNAMPGKTSA
Sbjct  181  LVTSTGPDHDKEFTAVVVVMDSEYGSGVGRSKKEAEQKAAAAAWKALEVLDNAMPGKTSA  240


>gi|71042598|pdb|2A11|A Chain A, Crystal Structure Of Nuclease Domain Of Ribonuclase 
Iii From Mycobacterium Tuberculosis
Length=242

 Score =  479 bits (1234),  Expect = 1e-133, Method: Compositional matrix adjust.
 Identities = 240/240 (100%), Positives = 240/240 (100%), Gaps = 0/240 (0%)

Query  1    MIRSRQPLLDALGVDLPDELLSLALTHRSYAYENGGLPTNERLEFLGDAVLGLTITDALF  60
            MIRSRQPLLDALGVDLPDELLSLALTHRSYAYENGGLPTNERLEFLGDAVLGLTITDALF
Sbjct  3    MIRSRQPLLDALGVDLPDELLSLALTHRSYAYENGGLPTNERLEFLGDAVLGLTITDALF  62

Query  61   HRHPDRSEGDLAKLRASVVNTQALADVARRLCAEGLGVHVLLGRGEANTGGADKSSILAD  120
            HRHPDRSEGDLAKLRASVVNTQALADVARRLCAEGLGVHVLLGRGEANTGGADKSSILAD
Sbjct  63   HRHPDRSEGDLAKLRASVVNTQALADVARRLCAEGLGVHVLLGRGEANTGGADKSSILAD  122

Query  121  GMESLLGAIYLQHGMEKAREVILRLFGPLLDAAPTLGAGLDWKTSLQELTAARGLGAPSY  180
            GMESLLGAIYLQHGMEKAREVILRLFGPLLDAAPTLGAGLDWKTSLQELTAARGLGAPSY
Sbjct  123  GMESLLGAIYLQHGMEKAREVILRLFGPLLDAAPTLGAGLDWKTSLQELTAARGLGAPSY  182

Query  181  LVTSTGPDHDKEFTAVVVVMDSEYGSGVGRSKKEAEQKAAAAAWKALEVLDNAMPGKTSA  240
            LVTSTGPDHDKEFTAVVVVMDSEYGSGVGRSKKEAEQKAAAAAWKALEVLDNAMPGKTSA
Sbjct  183  LVTSTGPDHDKEFTAVVVVMDSEYGSGVGRSKKEAEQKAAAAAWKALEVLDNAMPGKTSA  242


>gi|240169618|ref|ZP_04748277.1| ribonuclease III [Mycobacterium kansasii ATCC 12478]
Length=241

 Score =  416 bits (1069),  Expect = 1e-114, Method: Compositional matrix adjust.
 Identities = 208/231 (91%), Positives = 218/231 (95%), Gaps = 0/231 (0%)

Query  1    MIRSRQPLLDALGVDLPDELLSLALTHRSYAYENGGLPTNERLEFLGDAVLGLTITDALF  60
            M  SRQ LLDALGVDL DELLSLALTHRSYAYENGGLPTNERLEFLGDAVLGLTITD L+
Sbjct  1    MTASRQSLLDALGVDLSDELLSLALTHRSYAYENGGLPTNERLEFLGDAVLGLTITDELY  60

Query  61   HRHPDRSEGDLAKLRASVVNTQALADVARRLCAEGLGVHVLLGRGEANTGGADKSSILAD  120
            HRHPDRSEGDLAKLRASVVNTQALADVAR L   GLGVH+LLGRGEANTGGADKSSILAD
Sbjct  61   HRHPDRSEGDLAKLRASVVNTQALADVARNLSDNGLGVHILLGRGEANTGGADKSSILAD  120

Query  121  GMESLLGAIYLQHGMEKAREVILRLFGPLLDAAPTLGAGLDWKTSLQELTAARGLGAPSY  180
            GMESLLGAIYLQHG+E +R+VIL+LFGPLLDAA TLGAGLDWKTSLQELTAARGLG PSY
Sbjct  121  GMESLLGAIYLQHGIEVSRKVILKLFGPLLDAAATLGAGLDWKTSLQELTAARGLGTPSY  180

Query  181  LVTSTGPDHDKEFTAVVVVMDSEYGSGVGRSKKEAEQKAAAAAWKALEVLD  231
            LVTSTGPDHDKEFTAVVVVMD+EYGSG+GRSKKEAEQKAA+AA+KALE LD
Sbjct  181  LVTSTGPDHDKEFTAVVVVMDAEYGSGMGRSKKEAEQKAASAAYKALEALD  231


>gi|296171390|ref|ZP_06852723.1| ribonuclease III [Mycobacterium parascrofulaceum ATCC BAA-614]
 gi|295894165|gb|EFG73924.1| ribonuclease III [Mycobacterium parascrofulaceum ATCC BAA-614]
Length=237

 Score =  401 bits (1031),  Expect = 4e-110, Method: Compositional matrix adjust.
 Identities = 214/239 (90%), Positives = 228/239 (96%), Gaps = 2/239 (0%)

Query  2    IRSRQPLLDALGVDLPDELLSLALTHRSYAYENGGLPTNERLEFLGDAVLGLTITDALFH  61
            + SR+ LL+ALGV+LPDELLSLALTHRSYAYE+GGLPTNERLEFLGDAVLGLTITD L+H
Sbjct  1    MTSREDLLEALGVELPDELLSLALTHRSYAYEHGGLPTNERLEFLGDAVLGLTITDELYH  60

Query  62   RHPDRSEGDLAKLRASVVNTQALADVARRLCAEGLGVHVLLGRGEANTGGADKSSILADG  121
            RHPDRSEGDLAKLRASVVNTQALADVAR+L A+GLGVH+ LGRGEANTGGADKSSILADG
Sbjct  61   RHPDRSEGDLAKLRASVVNTQALADVARKLSADGLGVHLFLGRGEANTGGADKSSILADG  120

Query  122  MESLLGAIYLQHGMEKAREVILRLFGPLLDAAPTLGAGLDWKTSLQELTAARGLGAPSYL  181
            MESLLGAIYLQHG++ AREVILRLFG LLDAAPTLGAGLDWKTSLQELTAARG+GAPSY+
Sbjct  121  MESLLGAIYLQHGIDTAREVILRLFGGLLDAAPTLGAGLDWKTSLQELTAARGMGAPSYV  180

Query  182  VTSTGPDHDKEFTAVVVVMDSEYGSGVGRSKKEAEQKAAAAAWKALEVLDNAMPGKTSA  240
            VTSTGPDHDKEFTAVVVVMD+EYGSGVGRSKKEAEQKAAAA WKALEVLD A  GKTSA
Sbjct  181  VTSTGPDHDKEFTAVVVVMDTEYGSGVGRSKKEAEQKAAAATWKALEVLDTA--GKTSA  237


>gi|254233016|ref|ZP_04926343.1| ribonuclease III rnc (RNase III) [Mycobacterium tuberculosis 
C]
 gi|124602075|gb|EAY61085.1| ribonuclease III rnc (RNase III) [Mycobacterium tuberculosis 
C]
Length=198

 Score =  394 bits (1012),  Expect = 5e-108, Method: Compositional matrix adjust.
 Identities = 197/198 (99%), Positives = 198/198 (100%), Gaps = 0/198 (0%)

Query  43   LEFLGDAVLGLTITDALFHRHPDRSEGDLAKLRASVVNTQALADVARRLCAEGLGVHVLL  102
            +EFLGDAVLGLTITDALFHRHPDRSEGDLAKLRASVVNTQALADVARRLCAEGLGVHVLL
Sbjct  1    MEFLGDAVLGLTITDALFHRHPDRSEGDLAKLRASVVNTQALADVARRLCAEGLGVHVLL  60

Query  103  GRGEANTGGADKSSILADGMESLLGAIYLQHGMEKAREVILRLFGPLLDAAPTLGAGLDW  162
            GRGEANTGGADKSSILADGMESLLGAIYLQHGMEKAREVILRLFGPLLDAAPTLGAGLDW
Sbjct  61   GRGEANTGGADKSSILADGMESLLGAIYLQHGMEKAREVILRLFGPLLDAAPTLGAGLDW  120

Query  163  KTSLQELTAARGLGAPSYLVTSTGPDHDKEFTAVVVVMDSEYGSGVGRSKKEAEQKAAAA  222
            KTSLQELTAARGLGAPSYLVTSTGPDHDKEFTAVVVVMDSEYGSGVGRSKKEAEQKAAAA
Sbjct  121  KTSLQELTAARGLGAPSYLVTSTGPDHDKEFTAVVVVMDSEYGSGVGRSKKEAEQKAAAA  180

Query  223  AWKALEVLDNAMPGKTSA  240
            AWKALEVLDNAMPGKTSA
Sbjct  181  AWKALEVLDNAMPGKTSA  198


>gi|118617606|ref|YP_905938.1| ribonuclease III [Mycobacterium ulcerans Agy99]
 gi|118569716|gb|ABL04467.1| ribonuclease III Rnc [Mycobacterium ulcerans Agy99]
Length=243

 Score =  382 bits (982),  Expect = 2e-104, Method: Compositional matrix adjust.
 Identities = 198/243 (82%), Positives = 213/243 (88%), Gaps = 3/243 (1%)

Query  1    MIRSRQPLLDALGVDLPDELLSLALTHRSYAYENGGLPTNERLEFLGDAVLGLTITDALF  60
            M  SRQ LLDA+GV+LP+EL++LALTHRSYAYENGGLPTNERLEFLGDAVLGLTITD LF
Sbjct  1    MSVSRQALLDAVGVELPEELVTLALTHRSYAYENGGLPTNERLEFLGDAVLGLTITDELF  60

Query  61   HRHPDRSEGDLAKLRASVVNTQALADVARRLCAEGLGVHVLLGRGEANTGGADKSSILAD  120
            HRHP+RSEGDLAKLRASVVNTQALADVAR L   GLG H+LLGRGEANTGGADKSSILAD
Sbjct  61   HRHPERSEGDLAKLRASVVNTQALADVARHLSDHGLGAHMLLGRGEANTGGADKSSILAD  120

Query  121  GMESLLGAIYLQHGMEKAREVILRLFGPLLDAAPTLGAGLDWKTSLQELTAARGLGAPSY  180
            GMESLLGAIYL HGME ARE ILR+FGPLLDAAPTLGAGLDWKTSLQELTA+R LGAPSY
Sbjct  121  GMESLLGAIYLHHGMEVAREAILRIFGPLLDAAPTLGAGLDWKTSLQELTASRSLGAPSY  180

Query  181  LVTSTGPDHDKEFTAVVVVMDSEYGSGVGRS---KKEAEQKAAAAAWKALEVLDNAMPGK  237
             VTSTGPDH KEFTAVVVV ++EYGSGVGRS    ++    AA  A + LEVLD AMPG 
Sbjct  181  AVTSTGPDHHKEFTAVVVVNNTEYGSGVGRSKKEAEQKAAAAAYQALEGLEVLDGAMPGN  240

Query  238  TSA  240
            +SA
Sbjct  241  SSA  243


>gi|183981795|ref|YP_001850086.1| ribonuclease III Rnc [Mycobacterium marinum M]
 gi|183175121|gb|ACC40231.1| ribonuclease III Rnc [Mycobacterium marinum M]
Length=241

 Score =  382 bits (981),  Expect = 2e-104, Method: Compositional matrix adjust.
 Identities = 197/240 (83%), Positives = 212/240 (89%), Gaps = 3/240 (1%)

Query  4    SRQPLLDALGVDLPDELLSLALTHRSYAYENGGLPTNERLEFLGDAVLGLTITDALFHRH  63
            SRQ LLDA+GV+LP+EL++LALTHRSYAYENGGLPTNERLEFLGDAVLGLTITD LFHRH
Sbjct  2    SRQALLDAVGVELPEELVTLALTHRSYAYENGGLPTNERLEFLGDAVLGLTITDELFHRH  61

Query  64   PDRSEGDLAKLRASVVNTQALADVARRLCAEGLGVHVLLGRGEANTGGADKSSILADGME  123
            P+RSEGDLAKLRASVVNTQALADVAR L   GLG H+LLGRGEANTGGADKSSILADGME
Sbjct  62   PERSEGDLAKLRASVVNTQALADVARHLSEHGLGAHMLLGRGEANTGGADKSSILADGME  121

Query  124  SLLGAIYLQHGMEKAREVILRLFGPLLDAAPTLGAGLDWKTSLQELTAARGLGAPSYLVT  183
            SLLGAIYL HGME ARE ILR+FGPLLDAAPTLGAGLDWKTSLQELTA+R LGAPSY VT
Sbjct  122  SLLGAIYLHHGMEVAREAILRIFGPLLDAAPTLGAGLDWKTSLQELTASRSLGAPSYAVT  181

Query  184  STGPDHDKEFTAVVVVMDSEYGSGVGRS---KKEAEQKAAAAAWKALEVLDNAMPGKTSA  240
            STGPDH KEFTAVVVV ++EYGSGVGRS    ++    AA  A + LEVLD AMPG +SA
Sbjct  182  STGPDHHKEFTAVVVVNNTEYGSGVGRSKKEAEQKAAAAAYQALEGLEVLDGAMPGNSSA  241


>gi|15827877|ref|NP_302140.1| ribonuclease III [Mycobacterium leprae TN]
 gi|221230354|ref|YP_002503770.1| ribonuclease III [Mycobacterium leprae Br4923]
 gi|7531192|sp|O69469.1|RNC_MYCLE RecName: Full=Ribonuclease 3; AltName: Full=Ribonuclease III; 
Short=RNase III
 gi|3150224|emb|CAA19196.1| ribonuclease III [Mycobacterium leprae]
 gi|13093430|emb|CAC30612.1| RNAse III [Mycobacterium leprae]
 gi|219933461|emb|CAR71754.1| RNAse III [Mycobacterium leprae Br4923]
Length=238

 Score =  382 bits (980),  Expect = 3e-104, Method: Compositional matrix adjust.
 Identities = 205/239 (86%), Positives = 217/239 (91%), Gaps = 2/239 (0%)

Query  1    MIRSRQPLLDALGVDLPDELLSLALTHRSYAYENGGLPTNERLEFLGDAVLGLTITDALF  60
            M + RQ LLDA GVDLPDELLSLALTHRSYAYE+GGLPTNERLEFLGDAVL LTITD LF
Sbjct  1    MTQPRQALLDAFGVDLPDELLSLALTHRSYAYEHGGLPTNERLEFLGDAVLSLTITDELF  60

Query  61   HRHPDRSEGDLAKLRASVVNTQALADVARRLCAEGLGVHVLLGRGEANTGGADKSSILAD  120
            HRHPDRSEGDLAKLRASVVNTQALA VAR L   GLGV++LLGRGE NTGGADKSSILAD
Sbjct  61   HRHPDRSEGDLAKLRASVVNTQALAYVARNLSDGGLGVYLLLGRGETNTGGADKSSILAD  120

Query  121  GMESLLGAIYLQHGMEKAREVILRLFGPLLDAAPTLGAGLDWKTSLQELTAARGLGAPSY  180
            GMESLLGAIYL HG+E AR+VILRLFG LLDAAPTLGAGLDWKTSLQELTAARG+G PSY
Sbjct  121  GMESLLGAIYLHHGIEVARQVILRLFGTLLDAAPTLGAGLDWKTSLQELTAARGMGVPSY  180

Query  181  LVTSTGPDHDKEFTAVVVVMDSEYGSGVGRSKKEAEQKAAAAAWKALEVLDNAMPGKTS  239
            +VTSTGPDHDKEFTAVVVVMD+EYGSG+G SKKEAEQKAA+AAWKAL+VL     GKTS
Sbjct  181  VVTSTGPDHDKEFTAVVVVMDTEYGSGIGHSKKEAEQKAASAAWKALDVLGGV--GKTS  237


>gi|41409093|ref|NP_961929.1| ribonuclease III [Mycobacterium avium subsp. paratuberculosis 
K-10]
 gi|81413486|sp|Q73VL8.1|RNC_MYCPA RecName: Full=Ribonuclease 3; AltName: Full=Ribonuclease III; 
Short=RNase III
 gi|41397452|gb|AAS05312.1| Rnc [Mycobacterium avium subsp. paratuberculosis K-10]
Length=237

 Score =  379 bits (973),  Expect = 2e-103, Method: Compositional matrix adjust.
 Identities = 213/239 (90%), Positives = 228/239 (96%), Gaps = 2/239 (0%)

Query  2    IRSRQPLLDALGVDLPDELLSLALTHRSYAYENGGLPTNERLEFLGDAVLGLTITDALFH  61
            + SRQPLLDALGV+LPDELLSLALTHRSYAYE+GGLPTNERLEFLGDAVLGLTITDAL+H
Sbjct  1    MSSRQPLLDALGVELPDELLSLALTHRSYAYEHGGLPTNERLEFLGDAVLGLTITDALYH  60

Query  62   RHPDRSEGDLAKLRASVVNTQALADVARRLCAEGLGVHVLLGRGEANTGGADKSSILADG  121
            RHPDR+EGDLAKLRASVVNTQALADVAR+LC  GLG H+LLGRGEANTGGADKSSILADG
Sbjct  61   RHPDRTEGDLAKLRASVVNTQALADVARKLCDGGLGAHLLLGRGEANTGGADKSSILADG  120

Query  122  MESLLGAIYLQHGMEKAREVILRLFGPLLDAAPTLGAGLDWKTSLQELTAARGLGAPSYL  181
            MESLLGAIYLQHG++ AREVILRLFG LLDAAPTLGAGLDWKTSLQELTAARG+GAPSYL
Sbjct  121  MESLLGAIYLQHGIDTAREVILRLFGALLDAAPTLGAGLDWKTSLQELTAARGMGAPSYL  180

Query  182  VTSTGPDHDKEFTAVVVVMDSEYGSGVGRSKKEAEQKAAAAAWKALEVLDNAMPGKTSA  240
            VTSTGPDHDKEFTAVVVV D+EYG+GVGRSKKEAEQKAAAA WKAL+VLD+A   +TSA
Sbjct  181  VTSTGPDHDKEFTAVVVVADTEYGTGVGRSKKEAEQKAAAATWKALDVLDSA--AQTSA  237


>gi|336459093|gb|EGO38042.1| ribonuclease III [Mycobacterium avium subsp. paratuberculosis 
S397]
Length=237

 Score =  378 bits (970),  Expect = 5e-103, Method: Compositional matrix adjust.
 Identities = 212/239 (89%), Positives = 227/239 (95%), Gaps = 2/239 (0%)

Query  2    IRSRQPLLDALGVDLPDELLSLALTHRSYAYENGGLPTNERLEFLGDAVLGLTITDALFH  61
            + SRQPLLDALGV+LPDELLSLALTHRSYAYE+GGLPTNERLEFLGDAVLGLTITDAL+H
Sbjct  1    MSSRQPLLDALGVELPDELLSLALTHRSYAYEHGGLPTNERLEFLGDAVLGLTITDALYH  60

Query  62   RHPDRSEGDLAKLRASVVNTQALADVARRLCAEGLGVHVLLGRGEANTGGADKSSILADG  121
            RHPDR+EGDLAKLRASVVNTQALADVAR+LC  GLG H+LLGRGEANTGGADKSSILADG
Sbjct  61   RHPDRTEGDLAKLRASVVNTQALADVARKLCDGGLGAHLLLGRGEANTGGADKSSILADG  120

Query  122  MESLLGAIYLQHGMEKAREVILRLFGPLLDAAPTLGAGLDWKTSLQELTAARGLGAPSYL  181
            MESLLGAIYLQHG++ AREVILRLFG LLDAAPTLGAGLDWKTSLQELT ARG+GAPSYL
Sbjct  121  MESLLGAIYLQHGIDTAREVILRLFGALLDAAPTLGAGLDWKTSLQELTVARGMGAPSYL  180

Query  182  VTSTGPDHDKEFTAVVVVMDSEYGSGVGRSKKEAEQKAAAAAWKALEVLDNAMPGKTSA  240
            VTSTGPDHDKEFTAVVVV D+EYG+GVGRSKKEAEQKAAAA WKAL+VLD+A   +TSA
Sbjct  181  VTSTGPDHDKEFTAVVVVADTEYGTGVGRSKKEAEQKAAAATWKALDVLDSA--AQTSA  237


>gi|118462414|ref|YP_882955.1| ribonuclease III [Mycobacterium avium 104]
 gi|254776229|ref|ZP_05217745.1| ribonuclease III [Mycobacterium avium subsp. avium ATCC 25291]
 gi|118163701|gb|ABK64598.1| ribonuclease III [Mycobacterium avium 104]
Length=237

 Score =  377 bits (969),  Expect = 7e-103, Method: Compositional matrix adjust.
 Identities = 213/239 (90%), Positives = 227/239 (95%), Gaps = 2/239 (0%)

Query  2    IRSRQPLLDALGVDLPDELLSLALTHRSYAYENGGLPTNERLEFLGDAVLGLTITDALFH  61
            + SRQPLLDALGV+LPDELLSLALTHRSYAYE+GGLPTNERLEFLGDAVLGLTITDAL+H
Sbjct  1    MSSRQPLLDALGVELPDELLSLALTHRSYAYEHGGLPTNERLEFLGDAVLGLTITDALYH  60

Query  62   RHPDRSEGDLAKLRASVVNTQALADVARRLCAEGLGVHVLLGRGEANTGGADKSSILADG  121
            RHPDR+EGDLAKLRASVVNTQALADVAR+LC  GLG H+LLGRGEANTGGADKSSILADG
Sbjct  61   RHPDRTEGDLAKLRASVVNTQALADVARKLCDGGLGAHLLLGRGEANTGGADKSSILADG  120

Query  122  MESLLGAIYLQHGMEKAREVILRLFGPLLDAAPTLGAGLDWKTSLQELTAARGLGAPSYL  181
            MESLLGAIYLQHG++ AREVILRLFG LLDAAPTLGAGLDWKTSLQELTAARG+GAPSYL
Sbjct  121  MESLLGAIYLQHGIDTAREVILRLFGALLDAAPTLGAGLDWKTSLQELTAARGMGAPSYL  180

Query  182  VTSTGPDHDKEFTAVVVVMDSEYGSGVGRSKKEAEQKAAAAAWKALEVLDNAMPGKTSA  240
            VTSTGPDHDKEFTAVVVV D+EYG+GVGRSKKEAEQKAAAA WKAL+VLD A   +TSA
Sbjct  181  VTSTGPDHDKEFTAVVVVADTEYGTGVGRSKKEAEQKAAAATWKALDVLDPA--AQTSA  237


>gi|294993977|ref|ZP_06799668.1| ribonuclease III [Mycobacterium tuberculosis 210]
Length=188

 Score =  375 bits (963),  Expect = 3e-102, Method: Compositional matrix adjust.
 Identities = 187/188 (99%), Positives = 188/188 (100%), Gaps = 0/188 (0%)

Query  53   LTITDALFHRHPDRSEGDLAKLRASVVNTQALADVARRLCAEGLGVHVLLGRGEANTGGA  112
            +TITDALFHRHPDRSEGDLAKLRASVVNTQALADVARRLCAEGLGVHVLLGRGEANTGGA
Sbjct  1    MTITDALFHRHPDRSEGDLAKLRASVVNTQALADVARRLCAEGLGVHVLLGRGEANTGGA  60

Query  113  DKSSILADGMESLLGAIYLQHGMEKAREVILRLFGPLLDAAPTLGAGLDWKTSLQELTAA  172
            DKSSILADGMESLLGAIYLQHGMEKAREVILRLFGPLLDAAPTLGAGLDWKTSLQELTAA
Sbjct  61   DKSSILADGMESLLGAIYLQHGMEKAREVILRLFGPLLDAAPTLGAGLDWKTSLQELTAA  120

Query  173  RGLGAPSYLVTSTGPDHDKEFTAVVVVMDSEYGSGVGRSKKEAEQKAAAAAWKALEVLDN  232
            RGLGAPSYLVTSTGPDHDKEFTAVVVVMDSEYGSGVGRSKKEAEQKAAAAAWKALEVLDN
Sbjct  121  RGLGAPSYLVTSTGPDHDKEFTAVVVVMDSEYGSGVGRSKKEAEQKAAAAAWKALEVLDN  180

Query  233  AMPGKTSA  240
            AMPGKTSA
Sbjct  181  AMPGKTSA  188


>gi|254822109|ref|ZP_05227110.1| ribonuclease III [Mycobacterium intracellulare ATCC 13950]
Length=235

 Score =  370 bits (950),  Expect = 1e-100, Method: Compositional matrix adjust.
 Identities = 209/236 (89%), Positives = 222/236 (95%), Gaps = 1/236 (0%)

Query  2    IRSRQPLLDALGVDLPDELLSLALTHRSYAYENGGLPTNERLEFLGDAVLGLTITDALFH  61
            + SRQ LLDALGV+LPDELLSLALTHRSYAYE+GGLPTNERLEFLGDAVLGLTITD L+H
Sbjct  1    MSSRQALLDALGVELPDELLSLALTHRSYAYEHGGLPTNERLEFLGDAVLGLTITDELYH  60

Query  62   RHPDRSEGDLAKLRASVVNTQALADVARRLCAEGLGVHVLLGRGEANTGGADKSSILADG  121
            RHPDRSEGDLAKLRASVVNTQALADV R+LC  GLGVH+LLGRGEANTGGADKSSILADG
Sbjct  61   RHPDRSEGDLAKLRASVVNTQALADVGRKLCEGGLGVHLLLGRGEANTGGADKSSILADG  120

Query  122  MESLLGAIYLQHGMEKAREVILRLFGPLLDAAPTLGAGLDWKTSLQELTAARGLGAPSYL  181
            MESLLGAIYL+HG++ AREVILRLFGPLLDAAPTLGAGLDWKTSLQELTAAR +GAPSY+
Sbjct  121  MESLLGAIYLEHGIDVAREVILRLFGPLLDAAPTLGAGLDWKTSLQELTAARSMGAPSYV  180

Query  182  VTSTGPDHDKEFTAVVVVMDSEYGSGVGRSKKEAEQKAAAAAWKALEVLDNAMPGK  237
            VTSTGPDHDKEFTAVVVV D+EYGSGVGRSKKEAEQKAAAA WKALE LD  +PG 
Sbjct  181  VTSTGPDHDKEFTAVVVVADTEYGSGVGRSKKEAEQKAAAATWKALEALDT-VPGS  235


>gi|342858221|ref|ZP_08714876.1| ribonuclease III [Mycobacterium colombiense CECT 3035]
 gi|342133925|gb|EGT87105.1| ribonuclease III [Mycobacterium colombiense CECT 3035]
Length=237

 Score =  367 bits (941),  Expect = 9e-100, Method: Compositional matrix adjust.
 Identities = 205/238 (87%), Positives = 224/238 (95%), Gaps = 2/238 (0%)

Query  2    IRSRQPLLDALGVDLPDELLSLALTHRSYAYENGGLPTNERLEFLGDAVLGLTITDALFH  61
            + SRQ LLDALGV+L +ELLSLALTHRSYAYE+GGLPTNERLEFLGDAVLGLTITD L+H
Sbjct  1    MSSRQLLLDALGVELSEELLSLALTHRSYAYEHGGLPTNERLEFLGDAVLGLTITDELYH  60

Query  62   RHPDRSEGDLAKLRASVVNTQALADVARRLCAEGLGVHVLLGRGEANTGGADKSSILADG  121
            RHPDR+EGDLAKLRASVVNTQALADVAR+LC  GLGVH++LGRGEANTGGADKSSILADG
Sbjct  61   RHPDRTEGDLAKLRASVVNTQALADVARKLCEGGLGVHLMLGRGEANTGGADKSSILADG  120

Query  122  MESLLGAIYLQHGMEKAREVILRLFGPLLDAAPTLGAGLDWKTSLQELTAARGLGAPSYL  181
            MESLLGAIYL HG++ AR+VILRLFGPLLDAAPTLGAGLDWKTSLQELTAARG+GAPSY+
Sbjct  121  MESLLGAIYLDHGIDVARKVILRLFGPLLDAAPTLGAGLDWKTSLQELTAARGMGAPSYV  180

Query  182  VTSTGPDHDKEFTAVVVVMDSEYGSGVGRSKKEAEQKAAAAAWKALEVLDNAMPGKTS  239
            VTSTGPDHDKEFTAVVV+ ++EYG+GVGRSKKEAEQKAAAA WK L+VLD A  GKTS
Sbjct  181  VTSTGPDHDKEFTAVVVLAETEYGTGVGRSKKEAEQKAAAATWKTLDVLDPA--GKTS  236


>gi|118470776|ref|YP_886758.1| ribonuclease III [Mycobacterium smegmatis str. MC2 155]
 gi|118172063|gb|ABK72959.1| ribonuclease III [Mycobacterium smegmatis str. MC2 155]
Length=230

 Score =  362 bits (930),  Expect = 2e-98, Method: Compositional matrix adjust.
 Identities = 178/228 (79%), Positives = 203/228 (90%), Gaps = 0/228 (0%)

Query  1    MIRSRQPLLDALGVDLPDELLSLALTHRSYAYENGGLPTNERLEFLGDAVLGLTITDALF  60
            M  S   LL+ALGV LP ELL++ALTHRSY+YENGGLPTNERLEFLGDAVLGLTIT+ L+
Sbjct  1    MTDSHAALLEALGVALPAELLTIALTHRSYSYENGGLPTNERLEFLGDAVLGLTITEELY  60

Query  61   HRHPDRSEGDLAKLRASVVNTQALADVARRLCAEGLGVHVLLGRGEANTGGADKSSILAD  120
            HRHPDR+EGDLAKLRAS+VNTQALADV R L  EGLG H+ LG+GE N+GGADKSSILAD
Sbjct  61   HRHPDRAEGDLAKLRASIVNTQALADVGRGLTDEGLGAHLFLGKGEENSGGADKSSILAD  120

Query  121  GMESLLGAIYLQHGMEKAREVILRLFGPLLDAAPTLGAGLDWKTSLQELTAARGLGAPSY  180
            G+ESLLGAIYL+HG+   REVILRLFG LLD APTLGAGLDWK+SLQELTAARGLGAP+Y
Sbjct  121  GVESLLGAIYLEHGLTVVREVILRLFGELLDTAPTLGAGLDWKSSLQELTAARGLGAPAY  180

Query  181  LVTSTGPDHDKEFTAVVVVMDSEYGSGVGRSKKEAEQKAAAAAWKALE  228
            +VTSTGPDHDKEF+A VV+ ++EYG GVGR+KKEAE KAAA+A+K L+
Sbjct  181  VVTSTGPDHDKEFSATVVIGEAEYGHGVGRTKKEAELKAAASAYKTLD  228


>gi|333991297|ref|YP_004523911.1| ribonuclease III Rnc [Mycobacterium sp. JDM601]
 gi|333487265|gb|AEF36657.1| ribonuclease III Rnc [Mycobacterium sp. JDM601]
Length=233

 Score =  357 bits (916),  Expect = 8e-97, Method: Compositional matrix adjust.
 Identities = 176/211 (84%), Positives = 192/211 (91%), Gaps = 0/211 (0%)

Query  1    MIRSRQPLLDALGVDLPDELLSLALTHRSYAYENGGLPTNERLEFLGDAVLGLTITDALF  60
            M R RQ +L+ALGVDLPD+LL+LA+THRSYAYENGGLPTNERLEFLGDAVLGLTITD LF
Sbjct  1    MSRPRQAVLEALGVDLPDDLLTLAVTHRSYAYENGGLPTNERLEFLGDAVLGLTITDELF  60

Query  61   HRHPDRSEGDLAKLRASVVNTQALADVARRLCAEGLGVHVLLGRGEANTGGADKSSILAD  120
            HRHPDR EGDLAKLR+SVVNT ALADVAR L  +GLG H+LLGRGE NTGGADKSSILAD
Sbjct  61   HRHPDRPEGDLAKLRSSVVNTAALADVARGLTEDGLGAHLLLGRGEINTGGADKSSILAD  120

Query  121  GMESLLGAIYLQHGMEKAREVILRLFGPLLDAAPTLGAGLDWKTSLQELTAARGLGAPSY  180
             MESLLGA+YLQHG++ AREVILRLFGPLLD A TLGAGLDWKTSLQELTAARG+G P Y
Sbjct  121  SMESLLGAVYLQHGIDTAREVILRLFGPLLDTAATLGAGLDWKTSLQELTAARGIGVPCY  180

Query  181  LVTSTGPDHDKEFTAVVVVMDSEYGSGVGRS  211
             V+STGPDHD+EFTA+VVV D+EYGSGVGRS
Sbjct  181  QVSSTGPDHDREFTAIVVVSDTEYGSGVGRS  211


>gi|145224771|ref|YP_001135449.1| ribonuclease III [Mycobacterium gilvum PYR-GCK]
 gi|315445101|ref|YP_004077980.1| RNAse III [Mycobacterium sp. Spyr1]
 gi|145217257|gb|ABP46661.1| RNAse III [Mycobacterium gilvum PYR-GCK]
 gi|315263404|gb|ADU00146.1| RNAse III [Mycobacterium sp. Spyr1]
Length=234

 Score =  356 bits (913),  Expect = 2e-96, Method: Compositional matrix adjust.
 Identities = 175/228 (77%), Positives = 200/228 (88%), Gaps = 0/228 (0%)

Query  1    MIRSRQPLLDALGVDLPDELLSLALTHRSYAYENGGLPTNERLEFLGDAVLGLTITDALF  60
            M   R  LL ALG+DLP ELL++ALTHRSY+YENGG+PTNERLEFLGD+VLGLTIT+ L+
Sbjct  1    MTVDRALLLKALGIDLPAELLTIALTHRSYSYENGGVPTNERLEFLGDSVLGLTITEELY  60

Query  61   HRHPDRSEGDLAKLRASVVNTQALADVARRLCAEGLGVHVLLGRGEANTGGADKSSILAD  120
            HRHPDRSEGDLAKLRAS+VNTQALADV R L   GLG ++LLG+GE N+GGADKSSILAD
Sbjct  61   HRHPDRSEGDLAKLRASIVNTQALADVGRNLSEHGLGAYLLLGKGEENSGGADKSSILAD  120

Query  121  GMESLLGAIYLQHGMEKAREVILRLFGPLLDAAPTLGAGLDWKTSLQELTAARGLGAPSY  180
            G+ESLLGAIYL+HG   AREVILRLF  LLD APTLGAGLDWK+SLQELTA+  LGAPSY
Sbjct  121  GVESLLGAIYLEHGAVAAREVILRLFSDLLDTAPTLGAGLDWKSSLQELTASLALGAPSY  180

Query  181  LVTSTGPDHDKEFTAVVVVMDSEYGSGVGRSKKEAEQKAAAAAWKALE  228
             VTSTGPDHDKEFTAVV++ + E+G+GVGR+KKEAE KAA+AAW AL+
Sbjct  181  HVTSTGPDHDKEFTAVVIIAEREHGTGVGRTKKEAELKAASAAWNALQ  228


>gi|120403163|ref|YP_952992.1| ribonuclease III [Mycobacterium vanbaalenii PYR-1]
 gi|119955981|gb|ABM12986.1| RNAse III [Mycobacterium vanbaalenii PYR-1]
Length=235

 Score =  338 bits (867),  Expect = 4e-91, Method: Compositional matrix adjust.
 Identities = 180/227 (80%), Positives = 201/227 (89%), Gaps = 0/227 (0%)

Query  1    MIRSRQPLLDALGVDLPDELLSLALTHRSYAYENGGLPTNERLEFLGDAVLGLTITDALF  60
            M   R  LL+ALGVDLP ELL++ALTHRSY+YENGG+PTNERLEFLGD+VLGLTIT+ L+
Sbjct  1    MTVDRALLLEALGVDLPGELLTIALTHRSYSYENGGVPTNERLEFLGDSVLGLTITEELY  60

Query  61   HRHPDRSEGDLAKLRASVVNTQALADVARRLCAEGLGVHVLLGRGEANTGGADKSSILAD  120
            HRHPDRSEGDLAKLRAS+VNTQALADV R L   GLG ++LLG+GE N+GGADKSSILAD
Sbjct  61   HRHPDRSEGDLAKLRASIVNTQALADVGRNLTEHGLGAYLLLGKGEENSGGADKSSILAD  120

Query  121  GMESLLGAIYLQHGMEKAREVILRLFGPLLDAAPTLGAGLDWKTSLQELTAARGLGAPSY  180
            G+ESLLGAIYL+ G E AREVILRLF  LLD APTLGAGLDWK+SLQELTA+RGLGAP+Y
Sbjct  121  GVESLLGAIYLECGGEVAREVILRLFSSLLDTAPTLGAGLDWKSSLQELTASRGLGAPTY  180

Query  181  LVTSTGPDHDKEFTAVVVVMDSEYGSGVGRSKKEAEQKAAAAAWKAL  227
            +VTSTGPDHDKEFTA V+V DSE G GVGR+KKEAE KAAAAAW AL
Sbjct  181  VVTSTGPDHDKEFTAAVMVGDSECGRGVGRTKKEAELKAAAAAWHAL  227


>gi|108798917|ref|YP_639114.1| ribonuclease III [Mycobacterium sp. MCS]
 gi|119868032|ref|YP_937984.1| ribonuclease III [Mycobacterium sp. KMS]
 gi|126434517|ref|YP_001070208.1| ribonuclease III [Mycobacterium sp. JLS]
 gi|108769336|gb|ABG08058.1| RNAse III [Mycobacterium sp. MCS]
 gi|119694121|gb|ABL91194.1| RNAse III [Mycobacterium sp. KMS]
 gi|126234317|gb|ABN97717.1| RNAse III [Mycobacterium sp. JLS]
Length=234

 Score =  335 bits (859),  Expect = 4e-90, Method: Compositional matrix adjust.
 Identities = 165/211 (79%), Positives = 187/211 (89%), Gaps = 0/211 (0%)

Query  1    MIRSRQPLLDALGVDLPDELLSLALTHRSYAYENGGLPTNERLEFLGDAVLGLTITDALF  60
            M   R PLL ALGV LPD+LL++ALTHRSY+YE+GGLPTNERLEFLGD+VLGLTIT+ LF
Sbjct  1    MTLDRSPLLAALGVTLPDDLLTIALTHRSYSYEHGGLPTNERLEFLGDSVLGLTITEELF  60

Query  61   HRHPDRSEGDLAKLRASVVNTQALADVARRLCAEGLGVHVLLGRGEANTGGADKSSILAD  120
            HRHPDRSEGDLAKLRAS+VNT ALADV R+L  +GLG ++LLG+GE ++GGADKSSILAD
Sbjct  61   HRHPDRSEGDLAKLRASIVNTGALADVGRKLSDDGLGSYLLLGKGEESSGGADKSSILAD  120

Query  121  GMESLLGAIYLQHGMEKAREVILRLFGPLLDAAPTLGAGLDWKTSLQELTAARGLGAPSY  180
            G+ESLLGAIY+QHG+   REVILRLF  LLD APTLGAGLDWK+SLQELTAARGLGAP Y
Sbjct  121  GVESLLGAIYVQHGLTVTREVILRLFAGLLDTAPTLGAGLDWKSSLQELTAARGLGAPHY  180

Query  181  LVTSTGPDHDKEFTAVVVVMDSEYGSGVGRS  211
            +VTSTGPDHDKEFTA V+V D EYG GVGR+
Sbjct  181  VVTSTGPDHDKEFTATVLVTDIEYGRGVGRT  211


>gi|169630337|ref|YP_001703986.1| ribonuclease III [Mycobacterium abscessus ATCC 19977]
 gi|169242304|emb|CAM63332.1| Ribonuclease III Rnc [Mycobacterium abscessus]
Length=258

 Score =  325 bits (832),  Expect = 5e-87, Method: Compositional matrix adjust.
 Identities = 171/217 (79%), Positives = 191/217 (89%), Gaps = 0/217 (0%)

Query  11   ALGVDLPDELLSLALTHRSYAYENGGLPTNERLEFLGDAVLGLTITDALFHRHPDRSEGD  70
            A+GV L DELL+LALTHRSYAYENGGLPTNERLEFLGDAVLGLTIT+ L+H HPDRSEGD
Sbjct  15   AIGVQLGDELLTLALTHRSYAYENGGLPTNERLEFLGDAVLGLTITETLYHSHPDRSEGD  74

Query  71   LAKLRASVVNTQALADVARRLCAEGLGVHVLLGRGEANTGGADKSSILADGMESLLGAIY  130
            LAKLRAS+VNTQALA VAR L  +GLG H+LLG+GE NTGG DKSSILADGMES+LGA+Y
Sbjct  75   LAKLRASIVNTQALAGVARGLTGDGLGAHLLLGKGEENTGGRDKSSILADGMESILGAVY  134

Query  131  LQHGMEKAREVILRLFGPLLDAAPTLGAGLDWKTSLQELTAARGLGAPSYLVTSTGPDHD  190
            L+HG+E AR V+L LFG LL+ AP LGAGLDWKTSLQELTA +G GAPSY VTSTGPDHD
Sbjct  135  LEHGLETARAVVLTLFGELLETAPKLGAGLDWKTSLQELTAEKGWGAPSYAVTSTGPDHD  194

Query  191  KEFTAVVVVMDSEYGSGVGRSKKEAEQKAAAAAWKAL  227
            KEFTA V+V D+ +G GVGRSKKEAEQKAAA AW ++
Sbjct  195  KEFTATVMVNDTAHGVGVGRSKKEAEQKAAAEAWNSI  231


>gi|333920821|ref|YP_004494402.1| ribonuclease III [Amycolicicoccus subflavus DQS3-9A1]
 gi|333483042|gb|AEF41602.1| Ribonuclease III [Amycolicicoccus subflavus DQS3-9A1]
Length=283

 Score =  310 bits (794),  Expect = 1e-82, Method: Compositional matrix adjust.
 Identities = 157/225 (70%), Positives = 185/225 (83%), Gaps = 0/225 (0%)

Query  3    RSRQPLLDALGVDLPDELLSLALTHRSYAYENGGLPTNERLEFLGDAVLGLTITDALFHR  62
            +SR+ LL ALGV L ++LL+LALTHRSYAYENGGLPTNERLEFLGD+VLGLTIT+ L+  
Sbjct  55   QSRESLLAALGVRLGEDLLTLALTHRSYAYENGGLPTNERLEFLGDSVLGLTITEHLYRT  114

Query  63   HPDRSEGDLAKLRASVVNTQALADVARRLCAEGLGVHVLLGRGEANTGGADKSSILADGM  122
            HPD+ EG+LAK+R+SVVN  ALA+VAR L   GLG + LLG+GE  TGG DK+SILADGM
Sbjct  115  HPDKPEGELAKIRSSVVNMHALAEVARGLGHGGLGEYFLLGKGEEMTGGRDKASILADGM  174

Query  123  ESLLGAIYLQHGMEKAREVILRLFGPLLDAAPTLGAGLDWKTSLQELTAARGLGAPSYLV  182
            ESLLGA+YL+HG++ AR V+L LF  LL+  P LGAGLDWKTSLQELTA RGLG P+Y V
Sbjct  175  ESLLGAVYLEHGLDVARGVVLTLFKGLLERGPRLGAGLDWKTSLQELTAERGLGVPAYEV  234

Query  183  TSTGPDHDKEFTAVVVVMDSEYGSGVGRSKKEAEQKAAAAAWKAL  227
             + GPDHDKEFTA V+V   + GSG GR+KKEAEQKAA AAW+ L
Sbjct  235  AAKGPDHDKEFTATVIVAGEDLGSGTGRTKKEAEQKAAGAAWRHL  279


>gi|54026155|ref|YP_120397.1| ribonuclease III [Nocardia farcinica IFM 10152]
 gi|81373706|sp|Q5YS08.1|RNC_NOCFA RecName: Full=Ribonuclease 3; AltName: Full=Ribonuclease III; 
Short=RNase III
 gi|54017663|dbj|BAD59033.1| putative RNase III [Nocardia farcinica IFM 10152]
Length=240

 Score =  300 bits (767),  Expect = 2e-79, Method: Compositional matrix adjust.
 Identities = 162/220 (74%), Positives = 186/220 (85%), Gaps = 0/220 (0%)

Query  8    LLDALGVDLPDELLSLALTHRSYAYENGGLPTNERLEFLGDAVLGLTITDALFHRHPDRS  67
            LL+ALGVD+  +LL LALTHRSYAYENGGLPTNERLEFLGD+VLGL+IT+ L+H HPD+S
Sbjct  17   LLEALGVDVRPDLLRLALTHRSYAYENGGLPTNERLEFLGDSVLGLSITERLYHEHPDKS  76

Query  68   EGDLAKLRASVVNTQALADVARRLCAEGLGVHVLLGRGEANTGGADKSSILADGMESLLG  127
            EG+LAKLRASVVN  ALA+VAR L   GLG H+LLG+GE  TGG DK SILADGMESLLG
Sbjct  77   EGELAKLRASVVNMHALAEVARGLGEGGLGAHLLLGKGEELTGGRDKPSILADGMESLLG  136

Query  128  AIYLQHGMEKAREVILRLFGPLLDAAPTLGAGLDWKTSLQELTAARGLGAPSYLVTSTGP  187
            A++LQHG++ AR V+LRLF  LL+  P +GAGLDWKTSLQELTA RGLG PSY ++STGP
Sbjct  137  AVHLQHGIDVARGVVLRLFADLLERGPRMGAGLDWKTSLQELTAERGLGVPSYEISSTGP  196

Query  188  DHDKEFTAVVVVMDSEYGSGVGRSKKEAEQKAAAAAWKAL  227
            DHDKEFTA  V+    YG GVGRSKKEAEQKAA AA++AL
Sbjct  197  DHDKEFTATTVIGGRAYGQGVGRSKKEAEQKAAGAAYQAL  236


>gi|326382852|ref|ZP_08204542.1| ribonuclease III [Gordonia neofelifaecis NRRL B-59395]
 gi|326198442|gb|EGD55626.1| ribonuclease III [Gordonia neofelifaecis NRRL B-59395]
Length=234

 Score =  299 bits (765),  Expect = 2e-79, Method: Compositional matrix adjust.
 Identities = 151/221 (69%), Positives = 177/221 (81%), Gaps = 0/221 (0%)

Query  8    LLDALGVDLPDELLSLALTHRSYAYENGGLPTNERLEFLGDAVLGLTITDALFHRHPDRS  67
            L D LGV + DELL+LALTHRSYAYENGGLPTNERLEFLGDAVLG+ +T+ L+   PDR 
Sbjct  10   LTDVLGVTIDDELLTLALTHRSYAYENGGLPTNERLEFLGDAVLGVVVTERLYVGFPDRP  69

Query  68   EGDLAKLRASVVNTQALADVARRLCAEGLGVHVLLGRGEANTGGADKSSILADGMESLLG  127
            EG+LAK+RASVVN  ALADVAR L   GLG H+ LGRGE  TGG DK+SILADG+ESL G
Sbjct  70   EGELAKIRASVVNMHALADVARGLGEGGLGAHLRLGRGEELTGGRDKASILADGLESLFG  129

Query  128  AIYLQHGMEKAREVILRLFGPLLDAAPTLGAGLDWKTSLQELTAARGLGAPSYLVTSTGP  187
            AI+L HG+E A+ VI+ LF P++  +  LGAGLDWKTSLQEL+A R LG P Y ++STGP
Sbjct  130  AIFLDHGIEVAKTVIMNLFEPIIVRSGRLGAGLDWKTSLQELSAERSLGQPQYQISSTGP  189

Query  188  DHDKEFTAVVVVMDSEYGSGVGRSKKEAEQKAAAAAWKALE  228
            DH+KEFTAV VV   E G+G G++KKEAEQ+AA  AWKALE
Sbjct  190  DHNKEFTAVAVVGGDELGAGTGKTKKEAEQRAAELAWKALE  230


>gi|296139284|ref|YP_003646527.1| ribonuclease III [Tsukamurella paurometabola DSM 20162]
 gi|296027418|gb|ADG78188.1| ribonuclease III [Tsukamurella paurometabola DSM 20162]
Length=249

 Score =  294 bits (752),  Expect = 9e-78, Method: Compositional matrix adjust.
 Identities = 143/207 (70%), Positives = 175/207 (85%), Gaps = 0/207 (0%)

Query  5    RQPLLDALGVDLPDELLSLALTHRSYAYENGGLPTNERLEFLGDAVLGLTITDALFHRHP  64
            R PLL+ALGV+L DELL+LALTHRSYAYE GGLPTNERLEFLGD+VLG+++T+ L+  HP
Sbjct  13   RTPLLEALGVELDDELLTLALTHRSYAYEAGGLPTNERLEFLGDSVLGISVTEWLYVTHP  72

Query  65   DRSEGDLAKLRASVVNTQALADVARRLCAEGLGVHVLLGRGEANTGGADKSSILADGMES  124
            D+ EG+LAK+RASVVN  ALA VAR+L   GLG H+ LGRGE  TGG DK SILADGME+
Sbjct  73   DKPEGELAKIRASVVNMHALARVARKLGEGGLGAHLYLGRGEELTGGRDKDSILADGMEA  132

Query  125  LLGAIYLQHGMEKAREVILRLFGPLLDAAPTLGAGLDWKTSLQELTAARGLGAPSYLVTS  184
            LLGA++++HG++ AR V+LRLF P+L  + T+GAGLDWKTSLQELTA R LG P+Y +TS
Sbjct  133  LLGAVHIEHGIDTARSVVLRLFEPMLTTSSTMGAGLDWKTSLQELTAERDLGVPAYRITS  192

Query  185  TGPDHDKEFTAVVVVMDSEYGSGVGRS  211
            TGPDHDKEFTAVVV+ +++ G GVGR+
Sbjct  193  TGPDHDKEFTAVVVIDEADLGEGVGRT  219


>gi|312140459|ref|YP_004007795.1| ribonuclease iii [Rhodococcus equi 103S]
 gi|325675924|ref|ZP_08155607.1| ribonuclease III [Rhodococcus equi ATCC 33707]
 gi|311889798|emb|CBH49115.1| ribonuclease III [Rhodococcus equi 103S]
 gi|325553162|gb|EGD22841.1| ribonuclease III [Rhodococcus equi ATCC 33707]
Length=256

 Score =  293 bits (749),  Expect = 2e-77, Method: Compositional matrix adjust.
 Identities = 159/220 (73%), Positives = 184/220 (84%), Gaps = 0/220 (0%)

Query  8    LLDALGVDLPDELLSLALTHRSYAYENGGLPTNERLEFLGDAVLGLTITDALFHRHPDRS  67
            LL ALGV L ++LL+LALTHRSYAYE+GGLPTNERLEFLGD+VLGLTIT+ L+  HP++S
Sbjct  20   LLAALGVPLTEDLLTLALTHRSYAYEHGGLPTNERLEFLGDSVLGLTITERLYTAHPEKS  79

Query  68   EGDLAKLRASVVNTQALADVARRLCAEGLGVHVLLGRGEANTGGADKSSILADGMESLLG  127
            EG+LAK+RAS+VN  ALA+VAR L   GLG H+LLG+GE  TGG DK SILADGMESLLG
Sbjct  80   EGELAKIRASIVNMHALAEVARGLGPGGLGAHLLLGKGEEMTGGRDKPSILADGMESLLG  139

Query  128  AIYLQHGMEKAREVILRLFGPLLDAAPTLGAGLDWKTSLQELTAARGLGAPSYLVTSTGP  187
            AI+L+HG++ AR V+L LF  LL  AP LGAGLDWKTSLQELTA RG+G PSY +T+TGP
Sbjct  140  AIHLEHGIDTARRVVLDLFADLLSRAPKLGAGLDWKTSLQELTAERGIGVPSYEITATGP  199

Query  188  DHDKEFTAVVVVMDSEYGSGVGRSKKEAEQKAAAAAWKAL  227
            DHDKEFTA VVV    +G GVGRSKKEAEQKAA+ AW AL
Sbjct  200  DHDKEFTATVVVGGDAFGVGVGRSKKEAEQKAASTAWSAL  239


>gi|226365983|ref|YP_002783766.1| ribonuclease III [Rhodococcus opacus B4]
 gi|226244473|dbj|BAH54821.1| ribonuclease III [Rhodococcus opacus B4]
Length=252

 Score =  289 bits (740),  Expect = 2e-76, Method: Compositional matrix adjust.
 Identities = 155/220 (71%), Positives = 182/220 (83%), Gaps = 0/220 (0%)

Query  8    LLDALGVDLPDELLSLALTHRSYAYENGGLPTNERLEFLGDAVLGLTITDALFHRHPDRS  67
            LL ALGV++   LL+LALTHRSYAYENGGLPTNERLEFLGD+VLG+T+T+ L+  HPD+S
Sbjct  19   LLAALGVEIEPSLLTLALTHRSYAYENGGLPTNERLEFLGDSVLGVTVTEKLYLAHPDKS  78

Query  68   EGDLAKLRASVVNTQALADVARRLCAEGLGVHVLLGRGEANTGGADKSSILADGMESLLG  127
            EGDLAK+RAS+VN  ALA+VAR L   GLG H+LLG+GE  TGG DK SILADGMES+LG
Sbjct  79   EGDLAKIRASIVNMHALAEVARSLGEGGLGAHLLLGKGEEMTGGRDKPSILADGMESILG  138

Query  128  AIYLQHGMEKAREVILRLFGPLLDAAPTLGAGLDWKTSLQELTAARGLGAPSYLVTSTGP  187
            AI+L+HG++ AR V+L LF  LL  AP LGAGLDWKTSLQELTA RG+G P+Y +T+TGP
Sbjct  139  AIHLEHGIDTARRVVLDLFSDLLQRAPRLGAGLDWKTSLQELTAERGVGVPAYEITATGP  198

Query  188  DHDKEFTAVVVVMDSEYGSGVGRSKKEAEQKAAAAAWKAL  227
            DHDKEFTA V+V     G G+GRSKKEAEQKAA+ AW AL
Sbjct  199  DHDKEFTATVIVGGKPLGVGIGRSKKEAEQKAASTAWNAL  238


>gi|111023481|ref|YP_706453.1| ribonuclease III [Rhodococcus jostii RHA1]
 gi|110823011|gb|ABG98295.1| ribonuclease III [Rhodococcus jostii RHA1]
Length=252

 Score =  289 bits (739),  Expect = 3e-76, Method: Compositional matrix adjust.
 Identities = 155/220 (71%), Positives = 182/220 (83%), Gaps = 0/220 (0%)

Query  8    LLDALGVDLPDELLSLALTHRSYAYENGGLPTNERLEFLGDAVLGLTITDALFHRHPDRS  67
            LL ALGV++   LL+LALTHRSYAYENGGLPTNERLEFLGD+VLG+T+T+ L+  HPD+S
Sbjct  19   LLAALGVEIEPSLLTLALTHRSYAYENGGLPTNERLEFLGDSVLGVTVTEKLYLAHPDKS  78

Query  68   EGDLAKLRASVVNTQALADVARRLCAEGLGVHVLLGRGEANTGGADKSSILADGMESLLG  127
            EGDLAK+RAS+VN  ALA+VAR L   GLG H+LLG+GE  TGG DK SILADGMES+LG
Sbjct  79   EGDLAKIRASIVNMHALAEVARTLGEGGLGAHLLLGKGEEMTGGRDKPSILADGMESILG  138

Query  128  AIYLQHGMEKAREVILRLFGPLLDAAPTLGAGLDWKTSLQELTAARGLGAPSYLVTSTGP  187
            AI+L+HG++ AR V+L LF  LL  AP LGAGLDWKTSLQELTA RG+G P+Y +T+TGP
Sbjct  139  AIHLEHGIDTARRVVLDLFSDLLQRAPRLGAGLDWKTSLQELTAERGVGVPAYEITATGP  198

Query  188  DHDKEFTAVVVVMDSEYGSGVGRSKKEAEQKAAAAAWKAL  227
            DHDKEFTA V+V     G G+GRSKKEAEQKAA+ AW AL
Sbjct  199  DHDKEFTATVIVGGKPLGVGIGRSKKEAEQKAASTAWNAL  238


>gi|226305918|ref|YP_002765878.1| ribonuclease III [Rhodococcus erythropolis PR4]
 gi|226185035|dbj|BAH33139.1| probable ribonuclease III [Rhodococcus erythropolis PR4]
Length=257

 Score =  289 bits (739),  Expect = 3e-76, Method: Compositional matrix adjust.
 Identities = 156/224 (70%), Positives = 182/224 (82%), Gaps = 0/224 (0%)

Query  4    SRQPLLDALGVDLPDELLSLALTHRSYAYENGGLPTNERLEFLGDAVLGLTITDALFHRH  63
            +   LL A+GVD+   LL+LALTHRSYAYENGGLPTNERLEFLGD+VLG+T+T+ L+  H
Sbjct  15   NHDKLLAAVGVDIEPGLLTLALTHRSYAYENGGLPTNERLEFLGDSVLGVTVTENLYLSH  74

Query  64   PDRSEGDLAKLRASVVNTQALADVARRLCAEGLGVHVLLGRGEANTGGADKSSILADGME  123
            PD+SEGDLAK+RASVVN  ALA+VAR L   GLG H+LLG+GE  TGG DK SILADGME
Sbjct  75   PDKSEGDLAKIRASVVNMHALAEVARTLGEGGLGAHLLLGKGEEMTGGRDKPSILADGME  134

Query  124  SLLGAIYLQHGMEKAREVILRLFGPLLDAAPTLGAGLDWKTSLQELTAARGLGAPSYLVT  183
            S+LGAI+LQHG++ AR V+L LF  LL  AP LGAGLDWKTSLQELTA  G G P Y +T
Sbjct  135  SILGAIHLQHGIDTARRVVLDLFDDLLTRAPLLGAGLDWKTSLQELTAEHGAGVPVYEIT  194

Query  184  STGPDHDKEFTAVVVVMDSEYGSGVGRSKKEAEQKAAAAAWKAL  227
            +TGPDHDKEFTA V++ D   G GVGRSKKEAEQKAA++AWK +
Sbjct  195  ATGPDHDKEFTATVLISDKPLGVGVGRSKKEAEQKAASSAWKTM  238


>gi|331698524|ref|YP_004334763.1| Ribonuclease 3 [Pseudonocardia dioxanivorans CB1190]
 gi|326953213|gb|AEA26910.1| Ribonuclease 3 [Pseudonocardia dioxanivorans CB1190]
Length=238

 Score =  288 bits (738),  Expect = 4e-76, Method: Compositional matrix adjust.
 Identities = 151/221 (69%), Positives = 170/221 (77%), Gaps = 0/221 (0%)

Query  7    PLLDALGVDLPDELLSLALTHRSYAYENGGLPTNERLEFLGDAVLGLTITDALFHRHPDR  66
            PLL ALGV+L  ELL+LALTHRSYAYENGGLPTNERLEFLGD+VL + +T+ L+  HPD 
Sbjct  6    PLLRALGVELDPELLTLALTHRSYAYENGGLPTNERLEFLGDSVLSIVVTERLYLDHPDL  65

Query  67   SEGDLAKLRASVVNTQALADVARRLCAEGLGVHVLLGRGEANTGGADKSSILADGMESLL  126
             EG LAKLRASVVN  ALA VA  L  +GLG H+ LGRGE  TGG  K+SILAD  E+L+
Sbjct  66   PEGQLAKLRASVVNMNALAGVAAELVPDGLGAHLFLGRGEELTGGRAKASILADATEALI  125

Query  127  GAIYLQHGMEKAREVILRLFGPLLDAAPTLGAGLDWKTSLQELTAARGLGAPSYLVTSTG  186
            GA+YLQHG+E +R+VI RLF  LL  AP LGAGLDWKTSLQELTAA  LG P Y +T  G
Sbjct  126  GAVYLQHGLETSRDVIHRLFADLLRNAPLLGAGLDWKTSLQELTAAAELGVPEYRITEDG  185

Query  187  PDHDKEFTAVVVVMDSEYGSGVGRSKKEAEQKAAAAAWKAL  227
            PDH K FTA  VV   E GSG GR+KKEAEQKAAA AW+ L
Sbjct  186  PDHLKTFTATAVVGGRELGSGDGRTKKEAEQKAAALAWRTL  226


>gi|229491421|ref|ZP_04385245.1| ribonuclease III [Rhodococcus erythropolis SK121]
 gi|229321706|gb|EEN87503.1| ribonuclease III [Rhodococcus erythropolis SK121]
Length=257

 Score =  287 bits (734),  Expect = 1e-75, Method: Compositional matrix adjust.
 Identities = 156/220 (71%), Positives = 180/220 (82%), Gaps = 0/220 (0%)

Query  8    LLDALGVDLPDELLSLALTHRSYAYENGGLPTNERLEFLGDAVLGLTITDALFHRHPDRS  67
            LL A+GVD+   LL+LALTHRSYAYENGGLPTNERLEFLGD+VLG+T+T+ L+  HPD+S
Sbjct  19   LLAAVGVDIEPGLLTLALTHRSYAYENGGLPTNERLEFLGDSVLGVTVTENLYLSHPDKS  78

Query  68   EGDLAKLRASVVNTQALADVARRLCAEGLGVHVLLGRGEANTGGADKSSILADGMESLLG  127
            EGDLAK+RASVVN  ALA+VAR L   GLG H+LLG+GE  TGG DK SILADGMES+LG
Sbjct  79   EGDLAKIRASVVNMHALAEVARTLGEGGLGAHLLLGKGEEMTGGRDKPSILADGMESILG  138

Query  128  AIYLQHGMEKAREVILRLFGPLLDAAPTLGAGLDWKTSLQELTAARGLGAPSYLVTSTGP  187
            AI+LQHG+E AR V+L LF  LL  AP LGAGLDWKTSLQELTA  G G P Y +T+TGP
Sbjct  139  AIHLQHGIETARRVVLDLFDDLLTRAPLLGAGLDWKTSLQELTAEHGAGVPVYEITATGP  198

Query  188  DHDKEFTAVVVVMDSEYGSGVGRSKKEAEQKAAAAAWKAL  227
            DHDKEFTA V++     G GVGRSKKEAEQKAA++AWK +
Sbjct  199  DHDKEFTATVLISGKPLGVGVGRSKKEAEQKAASSAWKTM  238


>gi|238063283|ref|ZP_04607992.1| ribonuclease III [Micromonospora sp. ATCC 39149]
 gi|237885094|gb|EEP73922.1| ribonuclease III [Micromonospora sp. ATCC 39149]
Length=296

 Score =  285 bits (729),  Expect = 4e-75, Method: Compositional matrix adjust.
 Identities = 152/228 (67%), Positives = 173/228 (76%), Gaps = 3/228 (1%)

Query  3    RSRQP---LLDALGVDLPDELLSLALTHRSYAYENGGLPTNERLEFLGDAVLGLTITDAL  59
            R R P   L  A GV L  ELL  ALTHRSYAYENGGLPTNERLEFLGD+VLG+ IT AL
Sbjct  6    RRRAPIGHLEAAFGVSLDPELLERALTHRSYAYENGGLPTNERLEFLGDSVLGVVITTAL  65

Query  60   FHRHPDRSEGDLAKLRASVVNTQALADVARRLCAEGLGVHVLLGRGEANTGGADKSSILA  119
            FH HPD  EG LAKLRASVVN +ALADVAR L  +GLG ++LLG+GE +TGG DK+SILA
Sbjct  66   FHNHPDLPEGQLAKLRASVVNMRALADVARGLGPDGLGAYLLLGKGEESTGGRDKASILA  125

Query  120  DGMESLLGAIYLQHGMEKAREVILRLFGPLLDAAPTLGAGLDWKTSLQELTAARGLGAPS  179
            D +E+LLGAIYLQ+G++ A  VI RLF PL+  +   GA LDWKTSLQELTAA GLG P 
Sbjct  126  DTLEALLGAIYLQYGLDTAAIVIHRLFDPLMAESAGRGAALDWKTSLQELTAALGLGVPE  185

Query  180  YLVTSTGPDHDKEFTAVVVVMDSEYGSGVGRSKKEAEQKAAAAAWKAL  227
            Y +  TGPDH K FTA VVV  + YG   GRSKKEAEQ+AA +AW+ L
Sbjct  186  YRIEGTGPDHLKTFTAWVVVAGNRYGGAEGRSKKEAEQRAAESAWREL  233


>gi|330466266|ref|YP_004404009.1| ribonuclease iii [Verrucosispora maris AB-18-032]
 gi|328809237|gb|AEB43409.1| ribonuclease iii [Verrucosispora maris AB-18-032]
Length=287

 Score =  284 bits (727),  Expect = 7e-75, Method: Compositional matrix adjust.
 Identities = 147/217 (68%), Positives = 168/217 (78%), Gaps = 0/217 (0%)

Query  11   ALGVDLPDELLSLALTHRSYAYENGGLPTNERLEFLGDAVLGLTITDALFHRHPDRSEGD  70
            A GV +  ELL  ALTHRSYAYENGGLPTNERLEFLGD+VLG+ IT ALFH HPD  EG 
Sbjct  17   AFGVSMDPELLERALTHRSYAYENGGLPTNERLEFLGDSVLGVVITTALFHNHPDLPEGQ  76

Query  71   LAKLRASVVNTQALADVARRLCAEGLGVHVLLGRGEANTGGADKSSILADGMESLLGAIY  130
            LAKLRASVVN +ALADVAR L  +GLG ++LLG+GE  TGG DK+SILAD +E+LLGAIY
Sbjct  77   LAKLRASVVNMRALADVARGLGPDGLGPYLLLGKGEETTGGRDKASILADTLEALLGAIY  136

Query  131  LQHGMEKAREVILRLFGPLLDAAPTLGAGLDWKTSLQELTAARGLGAPSYLVTSTGPDHD  190
            LQ+G++ A EVI RLF PL+  +   GA LDWKTSLQELTAA GLG P Y +   GPDH 
Sbjct  137  LQYGLDTAAEVIHRLFDPLMAESAGRGAALDWKTSLQELTAALGLGVPEYRIEGAGPDHL  196

Query  191  KEFTAVVVVMDSEYGSGVGRSKKEAEQKAAAAAWKAL  227
            K FTA VVV  + YG   GRSKKEAEQ+AA +AW+ L
Sbjct  197  KTFTAWVVVAGNRYGGADGRSKKEAEQRAAESAWRTL  233


>gi|315502406|ref|YP_004081293.1| ribonuclease III [Micromonospora sp. L5]
 gi|315409025|gb|ADU07142.1| ribonuclease III [Micromonospora sp. L5]
Length=267

 Score =  284 bits (727),  Expect = 7e-75, Method: Compositional matrix adjust.
 Identities = 152/228 (67%), Positives = 172/228 (76%), Gaps = 3/228 (1%)

Query  3    RSRQP---LLDALGVDLPDELLSLALTHRSYAYENGGLPTNERLEFLGDAVLGLTITDAL  59
            R R P   L  A GV L  ELL  ALTHRSYAYENGGLPTNERLEFLGD+VLG+ IT AL
Sbjct  6    RRRAPVGHLEAAFGVSLDPELLERALTHRSYAYENGGLPTNERLEFLGDSVLGVVITTAL  65

Query  60   FHRHPDRSEGDLAKLRASVVNTQALADVARRLCAEGLGVHVLLGRGEANTGGADKSSILA  119
            FH HPD  EG LAKLRASVVN +ALADVAR L  +GLG ++LLG+GE  TGG DK+SILA
Sbjct  66   FHNHPDLPEGQLAKLRASVVNMRALADVARGLGPDGLGAYLLLGKGEEATGGRDKASILA  125

Query  120  DGMESLLGAIYLQHGMEKAREVILRLFGPLLDAAPTLGAGLDWKTSLQELTAARGLGAPS  179
            D +E+LLGAIYLQ+G++ A  VI RLF PL+  +   GA LDWKTSLQELTAA GLG P 
Sbjct  126  DTLEALLGAIYLQYGLDTAAIVIHRLFDPLMAESAGRGAALDWKTSLQELTAALGLGVPE  185

Query  180  YLVTSTGPDHDKEFTAVVVVMDSEYGSGVGRSKKEAEQKAAAAAWKAL  227
            Y +  TGPDH K FTA VVV  + YG   GRSKKEAEQ+AA +AW+ L
Sbjct  186  YRIEGTGPDHLKTFTAWVVVAGNRYGGAEGRSKKEAEQRAAESAWRTL  233


>gi|302865861|ref|YP_003834498.1| ribonuclease III [Micromonospora aurantiaca ATCC 27029]
 gi|302568720|gb|ADL44922.1| ribonuclease III [Micromonospora aurantiaca ATCC 27029]
Length=267

 Score =  284 bits (727),  Expect = 7e-75, Method: Compositional matrix adjust.
 Identities = 152/228 (67%), Positives = 172/228 (76%), Gaps = 3/228 (1%)

Query  3    RSRQP---LLDALGVDLPDELLSLALTHRSYAYENGGLPTNERLEFLGDAVLGLTITDAL  59
            R R P   L  A GV L  ELL  ALTHRSYAYENGGLPTNERLEFLGD+VLG+ IT AL
Sbjct  6    RRRAPVGHLEAAFGVSLDPELLERALTHRSYAYENGGLPTNERLEFLGDSVLGVVITTAL  65

Query  60   FHRHPDRSEGDLAKLRASVVNTQALADVARRLCAEGLGVHVLLGRGEANTGGADKSSILA  119
            FH HPD  EG LAKLRASVVN +ALADVAR L  +GLG ++LLG+GE  TGG DK+SILA
Sbjct  66   FHNHPDLPEGQLAKLRASVVNMRALADVARGLGPDGLGAYLLLGKGEEATGGRDKASILA  125

Query  120  DGMESLLGAIYLQHGMEKAREVILRLFGPLLDAAPTLGAGLDWKTSLQELTAARGLGAPS  179
            D +E+LLGAIYLQ+G++ A  VI RLF PL+  +   GA LDWKTSLQELTAA GLG P 
Sbjct  126  DTLEALLGAIYLQYGLDTAAIVIHRLFDPLMAESAGRGAALDWKTSLQELTAALGLGVPE  185

Query  180  YLVTSTGPDHDKEFTAVVVVMDSEYGSGVGRSKKEAEQKAAAAAWKAL  227
            Y +  TGPDH K FTA VVV  + YG   GRSKKEAEQ+AA +AW+ L
Sbjct  186  YRIEGTGPDHLKTFTAWVVVAGNRYGGAEGRSKKEAEQRAAESAWRTL  233


>gi|72161055|ref|YP_288712.1| ribonuclease III [Thermobifida fusca YX]
 gi|90101652|sp|Q47S78.1|RNC_THEFY RecName: Full=Ribonuclease 3; AltName: Full=Ribonuclease III; 
Short=RNase III
 gi|71914787|gb|AAZ54689.1| RNAse III [Thermobifida fusca YX]
Length=240

 Score =  281 bits (720),  Expect = 5e-74, Method: Compositional matrix adjust.
 Identities = 142/218 (66%), Positives = 171/218 (79%), Gaps = 3/218 (1%)

Query  10   DALGVDLPDELLSLALTHRSYAYENGGLPTNERLEFLGDAVLGLTITDALFHRHPDRSEG  69
            + +GV++  ++L+ ALTHRSYAYENGGLPTNERLEFLGD+VLGL +TD L+  HPD SEG
Sbjct  15   ETVGVEIAPDILTRALTHRSYAYENGGLPTNERLEFLGDSVLGLVVTDTLYRTHPDLSEG  74

Query  70   DLAKLRASVVNTQALADVARRLCAEGLGVHVLLGRGEANTGGADKSSILADGMESLLGAI  129
             LAKLRA+VVN +ALADVAR L   G+G +V LGRGE  TGG DKSSILAD +E+L+GA+
Sbjct  75   QLAKLRAAVVNMRALADVAREL---GIGRYVRLGRGEEATGGRDKSSILADTLEALIGAV  131

Query  130  YLQHGMEKAREVILRLFGPLLDAAPTLGAGLDWKTSLQELTAARGLGAPSYLVTSTGPDH  189
            YL  G+++A E++ RLF PL+  A  LGAGLDWKTSLQELTAA  LG P Y+V  +GPDH
Sbjct  132  YLDRGLDEASELVHRLFDPLIARASGLGAGLDWKTSLQELTAAELLGVPEYVVEESGPDH  191

Query  190  DKEFTAVVVVMDSEYGSGVGRSKKEAEQKAAAAAWKAL  227
             K F A V V    YGSG GRSKKEAEQ+AA +AWKA+
Sbjct  192  QKTFRATVRVAGQTYGSGEGRSKKEAEQQAAESAWKAI  229


>gi|262202009|ref|YP_003273217.1| ribonuclease III [Gordonia bronchialis DSM 43247]
 gi|262085356|gb|ACY21324.1| ribonuclease III [Gordonia bronchialis DSM 43247]
Length=262

 Score =  281 bits (719),  Expect = 6e-74, Method: Compositional matrix adjust.
 Identities = 147/220 (67%), Positives = 178/220 (81%), Gaps = 0/220 (0%)

Query  8    LLDALGVDLPDELLSLALTHRSYAYENGGLPTNERLEFLGDAVLGLTITDALFHRHPDRS  67
            LL A+   + ++LL+LALTHRSYAYENGGLPTNERLEFLGD+VLG+ IT+ L+  +PDR 
Sbjct  13   LLTAVDTTIGEQLLTLALTHRSYAYENGGLPTNERLEFLGDSVLGVVITERLYLSYPDRP  72

Query  68   EGDLAKLRASVVNTQALADVARRLCAEGLGVHVLLGRGEANTGGADKSSILADGMESLLG  127
            EG+LAK+RASVVN  ALADVAR L   GLG H+ LGRGE  TGG DK SILADG+ESL G
Sbjct  73   EGELAKIRASVVNMHALADVARSLGPGGLGRHLYLGRGEEMTGGRDKDSILADGLESLFG  132

Query  128  AIYLQHGMEKAREVILRLFGPLLDAAPTLGAGLDWKTSLQELTAARGLGAPSYLVTSTGP  187
            A++++HG+  ++ VILRLF  ++D A TLGAGLDWKTSLQEL+A +GLG P Y ++STGP
Sbjct  133  AVFIEHGLATSKRVILRLFDDVIDRAGTLGAGLDWKTSLQELSAEQGLGPPQYQISSTGP  192

Query  188  DHDKEFTAVVVVMDSEYGSGVGRSKKEAEQKAAAAAWKAL  227
            DH+KEFTAV VV     G+GVGR+KKEAEQ+AAA AWK L
Sbjct  193  DHNKEFTAVAVVAGESLGNGVGRTKKEAEQQAAARAWKTL  232


>gi|325000484|ref|ZP_08121596.1| RNAse III [Pseudonocardia sp. P1]
Length=249

 Score =  280 bits (717),  Expect = 1e-73, Method: Compositional matrix adjust.
 Identities = 148/231 (65%), Positives = 173/231 (75%), Gaps = 5/231 (2%)

Query  2    IRSRQPLLDALGVDLPDELLSLALTHRSYAYENGGLPTNERLEFLGDAVLGLTITDALFH  61
            +  R PLL ALGV+L +ELL+LALTHRSYAYE+GGLPTNERLEFLGD+VL + IT+ L+ 
Sbjct  10   VTDRSPLLSALGVELDEELLTLALTHRSYAYEHGGLPTNERLEFLGDSVLSIVITERLYR  69

Query  62   RHPDRSEGDLAKLRASVVNTQALADVARRL-----CAEGLGVHVLLGRGEANTGGADKSS  116
             HPD  EG LAKLRASVVN  ALA VA  L      ++GLG ++ LGRGE  TGG  K+S
Sbjct  70   DHPDLPEGQLAKLRASVVNMHALAGVAVALPTPGESSDGLGAYLYLGRGEELTGGRSKAS  129

Query  117  ILADGMESLLGAIYLQHGMEKAREVILRLFGPLLDAAPTLGAGLDWKTSLQELTAARGLG  176
            ILAD  E+LLGA+YLQHG+E +RE++ RLF  LL +AP LGAGLDWKTSLQELTAA G G
Sbjct  130  ILADATEALLGAVYLQHGLEPSRELVHRLFADLLHSAPLLGAGLDWKTSLQELTAAGGHG  189

Query  177  APSYLVTSTGPDHDKEFTAVVVVMDSEYGSGVGRSKKEAEQKAAAAAWKAL  227
             P Y +   GPDH K FTA  VV   + GSG GR+KKEAEQKAA  AW+ L
Sbjct  190  VPEYRIDEEGPDHLKVFTATAVVGGRDLGSGAGRTKKEAEQKAAELAWRTL  240


>gi|343925329|ref|ZP_08764854.1| ribonuclease 3 [Gordonia alkanivorans NBRC 16433]
 gi|343764768|dbj|GAA11780.1| ribonuclease 3 [Gordonia alkanivorans NBRC 16433]
Length=241

 Score =  277 bits (708),  Expect = 1e-72, Method: Compositional matrix adjust.
 Identities = 146/224 (66%), Positives = 179/224 (80%), Gaps = 1/224 (0%)

Query  5    RQPLLDALGVDLPDELLSLALTHRSYAYENGGLPTNERLEFLGDAVLGLTITDALFHRHP  64
            R+ LL AL  D+P++LL+LALTHRSYAYE+GGLPTNERLEFLGD+VLG+ IT+ L+   P
Sbjct  10   RRALLAALDTDIPEDLLTLALTHRSYAYEHGGLPTNERLEFLGDSVLGVVITERLYLHFP  69

Query  65   DRSEGDLAKLRASVVNTQALADVARRLCAEG-LGVHVLLGRGEANTGGADKSSILADGME  123
            DR EG+LAK+RASVVN  ALADVAR L  EG LG ++ LGRGE  TGG DK SILADG+E
Sbjct  70   DRPEGELAKIRASVVNMHALADVARGLGDEGGLGKYLYLGRGEEMTGGRDKDSILADGLE  129

Query  124  SLLGAIYLQHGMEKAREVILRLFGPLLDAAPTLGAGLDWKTSLQELTAARGLGAPSYLVT  183
            SL GA++L HG+E ++ +ILRLF   ++ A  LGAGLDWKTSLQEL++ RG G P Y ++
Sbjct  130  SLFGAVFLSHGLETSQRIILRLFDERIEKAGQLGAGLDWKTSLQELSSERGYGPPQYQIS  189

Query  184  STGPDHDKEFTAVVVVMDSEYGSGVGRSKKEAEQKAAAAAWKAL  227
            STGPDH+KEFTA+ ++     G GVGR+KKEAEQ+AAA AWKAL
Sbjct  190  STGPDHNKEFTAIAMIAGENLGEGVGRTKKEAEQQAAAHAWKAL  233


>gi|296393287|ref|YP_003658171.1| ribonuclease III [Segniliparus rotundus DSM 44985]
 gi|296180434|gb|ADG97340.1| ribonuclease III [Segniliparus rotundus DSM 44985]
Length=338

 Score =  275 bits (703),  Expect = 4e-72, Method: Compositional matrix adjust.
 Identities = 137/229 (60%), Positives = 176/229 (77%), Gaps = 0/229 (0%)

Query  8    LLDALGVDLPDELLSLALTHRSYAYENGGLPTNERLEFLGDAVLGLTITDALFHRHPDRS  67
            L ++LGV L D L++LALTHRS+A E+G +PTNERLEFLGD VLGL +T+ L+  HPD+ 
Sbjct  107  LFESLGVTLQDSLMTLALTHRSWANEHGEVPTNERLEFLGDTVLGLVVTEQLYVTHPDKE  166

Query  68   EGDLAKLRASVVNTQALADVARRLCAEGLGVHVLLGRGEANTGGADKSSILADGMESLLG  127
            EG+LAKLRA++V+T +LA++ARRL   GLG ++ LG GE  TGG +K SILADG+E+++G
Sbjct  167  EGELAKLRANIVSTASLAEIARRLGKGGLGEYLYLGNGEVRTGGKNKDSILADGLEAVIG  226

Query  128  AIYLQHGMEKAREVILRLFGPLLDAAPTLGAGLDWKTSLQELTAARGLGAPSYLVTSTGP  187
            A+++Q+G+EKAREV+L L  PLL  A  LGAGLDWKTSLQEL A RGL  P Y VT  GP
Sbjct  227  AVHIQYGIEKAREVVLALCAPLLARAARLGAGLDWKTSLQELCARRGLRPPVYEVTEAGP  286

Query  188  DHDKEFTAVVVVMDSEYGSGVGRSKKEAEQKAAAAAWKALEVLDNAMPG  236
            DH+K FTAVV++ +   G+G GR+KKEAE KAA  AW  +   D A+PG
Sbjct  287  DHEKLFTAVVLIEEKSLGTGSGRTKKEAEMKAAGHAWGVISGEDVALPG  335


>gi|289571114|ref|ZP_06451341.1| ribonuclease III rnc [Mycobacterium tuberculosis T17]
 gi|289544868|gb|EFD48516.1| ribonuclease III rnc [Mycobacterium tuberculosis T17]
Length=139

 Score =  275 bits (702),  Expect = 6e-72, Method: Compositional matrix adjust.
 Identities = 137/137 (100%), Positives = 137/137 (100%), Gaps = 0/137 (0%)

Query  1    MIRSRQPLLDALGVDLPDELLSLALTHRSYAYENGGLPTNERLEFLGDAVLGLTITDALF  60
            MIRSRQPLLDALGVDLPDELLSLALTHRSYAYENGGLPTNERLEFLGDAVLGLTITDALF
Sbjct  1    MIRSRQPLLDALGVDLPDELLSLALTHRSYAYENGGLPTNERLEFLGDAVLGLTITDALF  60

Query  61   HRHPDRSEGDLAKLRASVVNTQALADVARRLCAEGLGVHVLLGRGEANTGGADKSSILAD  120
            HRHPDRSEGDLAKLRASVVNTQALADVARRLCAEGLGVHVLLGRGEANTGGADKSSILAD
Sbjct  61   HRHPDRSEGDLAKLRASVVNTQALADVARRLCAEGLGVHVLLGRGEANTGGADKSSILAD  120

Query  121  GMESLLGAIYLQHGMEK  137
            GMESLLGAIYLQHGMEK
Sbjct  121  GMESLLGAIYLQHGMEK  137


>gi|317506412|ref|ZP_07964217.1| ribonuclease III [Segniliparus rugosus ATCC BAA-974]
 gi|316255292|gb|EFV14557.1| ribonuclease III [Segniliparus rugosus ATCC BAA-974]
Length=347

 Score =  273 bits (697),  Expect = 2e-71, Method: Compositional matrix adjust.
 Identities = 138/228 (61%), Positives = 174/228 (77%), Gaps = 0/228 (0%)

Query  8    LLDALGVDLPDELLSLALTHRSYAYENGGLPTNERLEFLGDAVLGLTITDALFHRHPDRS  67
            L D++GV L + LL+LALTHRS+A E+G +PTNERLEFLGD VLGL IT+ L+  HPD+ 
Sbjct  116  LFDSIGVTLQESLLTLALTHRSWANEHGEVPTNERLEFLGDTVLGLVITEQLYVTHPDKE  175

Query  68   EGDLAKLRASVVNTQALADVARRLCAEGLGVHVLLGRGEANTGGADKSSILADGMESLLG  127
            EG+LAKLRA++V+T +LA++ARRL   GLG ++ LG GE  TGG +K SILADG+E+LLG
Sbjct  176  EGELAKLRANIVSTISLAEIARRLGKGGLGEYLYLGNGEMRTGGKNKDSILADGLEALLG  235

Query  128  AIYLQHGMEKAREVILRLFGPLLDAAPTLGAGLDWKTSLQELTAARGLGAPSYLVTSTGP  187
            A+++Q+G+EKAREV+L L  PLL  A  LGAGLDWKTSLQEL A RGL  P Y V   GP
Sbjct  236  AVHIQYGIEKAREVVLHLCAPLLARAARLGAGLDWKTSLQELCARRGLRPPVYEVAEAGP  295

Query  188  DHDKEFTAVVVVMDSEYGSGVGRSKKEAEQKAAAAAWKALEVLDNAMP  235
            DH+K FTAVV++ +   G+G GR+KKEAE KAA  AW  +   D A+P
Sbjct  296  DHEKLFTAVVLIEEKSLGTGSGRTKKEAEMKAAGHAWGVISGEDVALP  343


>gi|311898536|dbj|BAJ30944.1| putative ribonuclease 3 [Kitasatospora setae KM-6054]
Length=269

 Score =  268 bits (684),  Expect = 7e-70, Method: Compositional matrix adjust.
 Identities = 138/222 (63%), Positives = 167/222 (76%), Gaps = 3/222 (1%)

Query  12   LGVDLPDELLSLALTHRSYAYENGGLPTNERLEFLGDAVLGLTITDALFHRHPDRSEGDL  71
            LG  L   LL  ALTHRSYAYENGGLPTNERLEFLGD+VLGL +TD L+  HP+ +EG L
Sbjct  35   LGYSLERALLVRALTHRSYAYENGGLPTNERLEFLGDSVLGLVVTDTLYRLHPEVAEGTL  94

Query  72   AKLRASVVNTQALADVARRLCAEGLGVHVLLGRGEANTGGADKSSILADGMESLLGAIYL  131
            AKLRA+VVN++ALA+V R L    LG  + LG+GE  TGG DKSSILAD +E+++GA YL
Sbjct  95   AKLRAAVVNSRALAEVGRGLD---LGAFIRLGKGEEGTGGRDKSSILADTVEAVIGATYL  151

Query  132  QHGMEKAREVILRLFGPLLDAAPTLGAGLDWKTSLQELTAARGLGAPSYLVTSTGPDHDK  191
              G++ A E + RLF PL+  +  LGAGLDWKTSLQELTAA GLG P Y+VT +GPDH+K
Sbjct  152  DQGLDAATEFVHRLFDPLIAESAQLGAGLDWKTSLQELTAAVGLGVPEYVVTESGPDHEK  211

Query  192  EFTAVVVVMDSEYGSGVGRSKKEAEQKAAAAAWKALEVLDNA  233
             FTA   V   ++GSG GRSKKEAEQKAA +AW+A++    A
Sbjct  212  TFTAAARVAGQDHGSGSGRSKKEAEQKAAESAWRAIKAQHEA  253


>gi|159036823|ref|YP_001536076.1| ribonuclease III [Salinispora arenicola CNS-205]
 gi|157915658|gb|ABV97085.1| Ribonuclease III [Salinispora arenicola CNS-205]
Length=252

 Score =  265 bits (678),  Expect = 4e-69, Method: Compositional matrix adjust.
 Identities = 148/217 (69%), Positives = 166/217 (77%), Gaps = 0/217 (0%)

Query  11   ALGVDLPDELLSLALTHRSYAYENGGLPTNERLEFLGDAVLGLTITDALFHRHPDRSEGD  70
            A GV L  ELL  ALTHRSYAYENGGLPTNERLEFLGD+VLG+ IT ALFH HPD  EG 
Sbjct  17   AFGVALDPELLERALTHRSYAYENGGLPTNERLEFLGDSVLGVVITTALFHNHPDLPEGQ  76

Query  71   LAKLRASVVNTQALADVARRLCAEGLGVHVLLGRGEANTGGADKSSILADGMESLLGAIY  130
            LAKLRASVVN +ALA+VAR L   GLG ++LLG+GE  TGG DK+SILAD +E+LLGAIY
Sbjct  77   LAKLRASVVNMRALAEVARALGPTGLGPYLLLGKGEETTGGRDKASILADTLEALLGAIY  136

Query  131  LQHGMEKAREVILRLFGPLLDAAPTLGAGLDWKTSLQELTAARGLGAPSYLVTSTGPDHD  190
            LQ G++ A  VI RLF PL+  +   GA LDWKTSLQELTAA+GLG P Y +  TGPDH 
Sbjct  137  LQCGLDTAATVIHRLFDPLMADSAGRGAALDWKTSLQELTAAQGLGVPEYRIEGTGPDHL  196

Query  191  KEFTAVVVVMDSEYGSGVGRSKKEAEQKAAAAAWKAL  227
            K FTA VVV    YG   GRSKKEAEQ+AA AAW+ L
Sbjct  197  KTFTAWVVVAGQRYGGAEGRSKKEAEQRAAEAAWRTL  233


>gi|312194940|ref|YP_004015001.1| ribonuclease III [Frankia sp. EuI1c]
 gi|311226276|gb|ADP79131.1| ribonuclease III [Frankia sp. EuI1c]
Length=319

 Score =  265 bits (678),  Expect = 4e-69, Method: Compositional matrix adjust.
 Identities = 138/212 (66%), Positives = 165/212 (78%), Gaps = 1/212 (0%)

Query  17   PDELLSLALTHRSYAYENGGLPTNERLEFLGDAVLGLTITDALFHRHPDRSEGDLAKLRA  76
            PD LL  ALTHRSYAYENGGLPTNERLEFLGDAVL L +TDAL++RHPD  EG LAK RA
Sbjct  43   PD-LLDRALTHRSYAYENGGLPTNERLEFLGDAVLQLVVTDALYNRHPDLPEGALAKQRA  101

Query  77   SVVNTQALADVARRLCAEGLGVHVLLGRGEANTGGADKSSILADGMESLLGAIYLQHGME  136
            SVVN++ALADVAR +  +G+G ++LLG+GE  TGG DK+SILAD +E+L+GA+YL+ G+E
Sbjct  102  SVVNSRALADVARVIGPKGIGPYLLLGKGEETTGGRDKASILADTLEALIGAVYLELGLE  161

Query  137  KAREVILRLFGPLLDAAPTLGAGLDWKTSLQELTAARGLGAPSYLVTSTGPDHDKEFTAV  196
             A +++ R F PLLD A   GAGLDWKTSLQE TA  G+G P Y+VT +GPDH K FTA 
Sbjct  162  VAAQLVHRYFDPLLDEAAGRGAGLDWKTSLQERTAELGMGPPDYVVTDSGPDHAKRFTAR  221

Query  197  VVVMDSEYGSGVGRSKKEAEQKAAAAAWKALE  228
              + D  YG G G SKKEAEQ+AA  A+ ALE
Sbjct  222  ARISDRIYGEGEGGSKKEAEQRAAERAFLALE  253


>gi|145593838|ref|YP_001158135.1| ribonuclease III [Salinispora tropica CNB-440]
 gi|145303175|gb|ABP53757.1| RNAse III [Salinispora tropica CNB-440]
Length=252

 Score =  265 bits (677),  Expect = 4e-69, Method: Compositional matrix adjust.
 Identities = 149/229 (66%), Positives = 172/229 (76%), Gaps = 4/229 (1%)

Query  3    RSRQPLLD----ALGVDLPDELLSLALTHRSYAYENGGLPTNERLEFLGDAVLGLTITDA  58
            + R+P++     A GV L  ELL  ALTHRSYAYENGGLPTNERLEFLGD+VLG+ IT A
Sbjct  5    KRRRPVVGHLEAAFGVALDPELLERALTHRSYAYENGGLPTNERLEFLGDSVLGVVITTA  64

Query  59   LFHRHPDRSEGDLAKLRASVVNTQALADVARRLCAEGLGVHVLLGRGEANTGGADKSSIL  118
            LFH HPD  EG LAKLRASVVN +ALA+VAR L   GLG ++LLG+GE +TGG DK+SIL
Sbjct  65   LFHNHPDLPEGQLAKLRASVVNMRALAEVARGLGPTGLGPYLLLGKGEESTGGRDKASIL  124

Query  119  ADGMESLLGAIYLQHGMEKAREVILRLFGPLLDAAPTLGAGLDWKTSLQELTAARGLGAP  178
            AD +E+LLGAIYL+ G+E    VI RLF PL+  +   GA LDWKTSLQELTAA+GLG P
Sbjct  125  ADTLEALLGAIYLESGLETVATVIHRLFDPLMAESAGRGAALDWKTSLQELTAAQGLGVP  184

Query  179  SYLVTSTGPDHDKEFTAVVVVMDSEYGSGVGRSKKEAEQKAAAAAWKAL  227
             Y +  TGPDH K FTA VVV    YG   GRSKKEAEQ+AA AAW+ L
Sbjct  185  EYRIEGTGPDHLKTFTAWVVVAGRRYGGAEGRSKKEAEQRAAEAAWRTL  233


>gi|288923504|ref|ZP_06417623.1| ribonuclease III [Frankia sp. EUN1f]
 gi|288345162|gb|EFC79572.1| ribonuclease III [Frankia sp. EUN1f]
Length=281

 Score =  264 bits (675),  Expect = 8e-69, Method: Compositional matrix adjust.
 Identities = 144/224 (65%), Positives = 165/224 (74%), Gaps = 0/224 (0%)

Query  5    RQPLLDALGVDLPDELLSLALTHRSYAYENGGLPTNERLEFLGDAVLGLTITDALFHRHP  64
            R  L++AL VD+  ELL  ALTHRSYAYENGGLPTNERLEFLGDAVLGL +T ALF RHP
Sbjct  11   RDGLVEALQVDVDPELLDRALTHRSYAYENGGLPTNERLEFLGDAVLGLIVTAALFRRHP  70

Query  65   DRSEGDLAKLRASVVNTQALADVARRLCAEGLGVHVLLGRGEANTGGADKSSILADGMES  124
            D  EG LAK RASVVN +ALADVARR+   G+G ++LLGRGE  TGG DK SILAD +E+
Sbjct  71   DLPEGQLAKQRASVVNMRALADVARRIGPTGIGPYLLLGRGEEATGGRDKPSILADTLEA  130

Query  125  LLGAIYLQHGMEKAREVILRLFGPLLDAAPTLGAGLDWKTSLQELTAARGLGAPSYLVTS  184
            ++GA+YL + ++ A   + RLF PLLD A   GAGLDWKTSLQE TA  GLG P Y+VT 
Sbjct  131  VIGAVYLSNSLDVASGFVHRLFDPLLDEAAGRGAGLDWKTSLQEQTALLGLGPPDYVVTE  190

Query  185  TGPDHDKEFTAVVVVMDSEYGSGVGRSKKEAEQKAAAAAWKALE  228
             GPDH K FTA   V     G G G SKKEAEQ+AAA A+  LE
Sbjct  191  AGPDHAKRFTAFARVAGEVLGEGEGGSKKEAEQRAAATAFAMLE  234


>gi|300783718|ref|YP_003764009.1| ribonuclease III [Amycolatopsis mediterranei U32]
 gi|299793232|gb|ADJ43607.1| ribonuclease III [Amycolatopsis mediterranei U32]
 gi|340525108|gb|AEK40313.1| ribonuclease III [Amycolatopsis mediterranei S699]
Length=234

 Score =  262 bits (669),  Expect = 3e-68, Method: Compositional matrix adjust.
 Identities = 147/220 (67%), Positives = 171/220 (78%), Gaps = 0/220 (0%)

Query  8    LLDALGVDLPDELLSLALTHRSYAYENGGLPTNERLEFLGDAVLGLTITDALFHRHPDRS  67
            +L+ALGV L  ELL L+LTHRSYAYENGGLP NERLEFLGDAVLGL +TD L++ HPD  
Sbjct  1    MLEALGVILDPELLRLSLTHRSYAYENGGLPPNERLEFLGDAVLGLVVTDHLYNTHPDLP  60

Query  68   EGDLAKLRASVVNTQALADVARRLCAEGLGVHVLLGRGEANTGGADKSSILADGMESLLG  127
            EG LAKLRASVVN  ALA VAR L   GLG H+LLG+GE  TGG DK+SILADG+E+++G
Sbjct  61   EGQLAKLRASVVNMHALARVARGLGEGGLGAHLLLGKGEELTGGRDKASILADGLEAVIG  120

Query  128  AIYLQHGMEKAREVILRLFGPLLDAAPTLGAGLDWKTSLQELTAARGLGAPSYLVTSTGP  187
            A+YL+HG+E AR+++  LF  LL  AP  GAGLDWKTSLQELTA+ GLG P Y V  TGP
Sbjct  121  AVYLEHGIEIARKLVHHLFDGLLAEAPLRGAGLDWKTSLQELTASAGLGVPEYKVEDTGP  180

Query  188  DHDKEFTAVVVVMDSEYGSGVGRSKKEAEQKAAAAAWKAL  227
            DH KEFTA V+V     G G G +KKEAEQKAA  AW++L
Sbjct  181  DHRKEFTATVLVAGRPLGHGAGSTKKEAEQKAAETAWRSL  220


>gi|284032688|ref|YP_003382619.1| ribonuclease III [Kribbella flavida DSM 17836]
 gi|283811981|gb|ADB33820.1| ribonuclease III [Kribbella flavida DSM 17836]
Length=249

 Score =  262 bits (669),  Expect = 3e-68, Method: Compositional matrix adjust.
 Identities = 136/216 (63%), Positives = 162/216 (75%), Gaps = 3/216 (1%)

Query  12   LGVDLPDELLSLALTHRSYAYENGGLPTNERLEFLGDAVLGLTITDALFHRHPDRSEGDL  71
            LGV L DELL  A THRS+AYENGGLPTNERLEFLGD+VLG+ +T++LF  HPD SEG L
Sbjct  23   LGVSLADELLEHAFTHRSFAYENGGLPTNERLEFLGDSVLGVIVTESLFRNHPDLSEGRL  82

Query  72   AKLRASVVNTQALADVARRLCAEGLGVHVLLGRGEANTGGADKSSILADGMESLLGAIYL  131
            AKLRA+VVN +ALA VAR L    LG ++ LGRGE  TGG DKSSILAD +E+L+GA+YL
Sbjct  83   AKLRAAVVNMRALAGVARDLK---LGKYLRLGRGEEATGGRDKSSILADCVEALIGAVYL  139

Query  132  QHGMEKAREVILRLFGPLLDAAPTLGAGLDWKTSLQELTAARGLGAPSYLVTSTGPDHDK  191
              G E A  V+  LF  L++++  LGAGLDWKTSLQEL A  G+G P Y++  +GPDH K
Sbjct  140  DRGFEVAGRVVHTLFDDLMESSARLGAGLDWKTSLQELVAQLGVGVPEYVIAESGPDHAK  199

Query  192  EFTAVVVVMDSEYGSGVGRSKKEAEQKAAAAAWKAL  227
             F A V +    YG G+GRSKKEAEQ+AA  AWKAL
Sbjct  200  TFEARVRIGSDTYGHGIGRSKKEAEQQAAETAWKAL  235


>gi|319948353|ref|ZP_08022497.1| ribonuclease III [Dietzia cinnamea P4]
 gi|319437984|gb|EFV92960.1| ribonuclease III [Dietzia cinnamea P4]
Length=237

 Score =  261 bits (667),  Expect = 6e-68, Method: Compositional matrix adjust.
 Identities = 140/225 (63%), Positives = 165/225 (74%), Gaps = 2/225 (0%)

Query  6    QP-LLDA-LGVDLPDELLSLALTHRSYAYENGGLPTNERLEFLGDAVLGLTITDALFHRH  63
            QP  LDA LGV LP  L + ALTHRSYAYE+GGLP NERLEFLGDAVL L +T+ L++ +
Sbjct  4    QPSALDAVLGVALPAGLATQALTHRSYAYEHGGLPHNERLEFLGDAVLELVVTEYLYNAY  63

Query  64   PDRSEGDLAKLRASVVNTQALADVARRLCAEGLGVHVLLGRGEANTGGADKSSILADGME  123
            PDR EGDLAK+RAS+VNT  LAD+AR L   GLG H+ LGRGE  TGG DK SILAD +E
Sbjct  64   PDRPEGDLAKIRASLVNTYVLADIARELGDGGLGRHLRLGRGEELTGGRDKHSILADTLE  123

Query  124  SLLGAIYLQHGMEKAREVILRLFGPLLDAAPTLGAGLDWKTSLQELTAARGLGAPSYLVT  183
            ++ G++YL HG+E AR +I ++ G  L   P LGA LDWKTSLQE  A+ G     Y +T
Sbjct  124  AVFGSVYLTHGLETARGLIEKIIGDRLTVVPHLGAALDWKTSLQEKCASLGRSKARYEIT  183

Query  184  STGPDHDKEFTAVVVVMDSEYGSGVGRSKKEAEQKAAAAAWKALE  228
            STGPDHDK F+AVV V D   G G GR+KKEAEQKAA  AW AL+
Sbjct  184  STGPDHDKTFSAVVFVGDDPLGEGTGRTKKEAEQKAAEQAWAALD  228


>gi|258652105|ref|YP_003201261.1| ribonuclease III [Nakamurella multipartita DSM 44233]
 gi|258555330|gb|ACV78272.1| ribonuclease III [Nakamurella multipartita DSM 44233]
Length=249

 Score =  260 bits (665),  Expect = 1e-67, Method: Compositional matrix adjust.
 Identities = 139/218 (64%), Positives = 167/218 (77%), Gaps = 3/218 (1%)

Query  11   ALGVDLPDELLSLALTHRSYAYENGGLPTNERLEFLGDAVLGLTITDALFHRHPDRSEGD  70
            ALGV+L  EL+ LALTHRS+AYE+GGLPTNERLEFLGD+VLG+ +T+ L+  HP+  EG 
Sbjct  16   ALGVELSPELVVLALTHRSFAYEHGGLPTNERLEFLGDSVLGVVVTETLYRTHPELQEGR  75

Query  71   LAKLRASVVNTQALADVARRLCAEGLGVHVLLGRGEANTGGADKSSILADGMESLLGAIY  130
            LAKLRASVVN  ALA V R +   GLG  + LG+GE  TGG DKSSI+AD +E+++GA+Y
Sbjct  76   LAKLRASVVNMHALAGVGRTI---GLGDQLRLGKGEELTGGRDKSSIVADAVEAVIGAVY  132

Query  131  LQHGMEKAREVILRLFGPLLDAAPTLGAGLDWKTSLQELTAARGLGAPSYLVTSTGPDHD  190
            LQHG+E AR V+LRLF  LL  AP LGAGLDWKTSLQEL A RGLG P Y V+  GPDH 
Sbjct  133  LQHGLEVARAVVLRLFADLLATAPQLGAGLDWKTSLQELAAERGLGVPEYRVSEEGPDHA  192

Query  191  KEFTAVVVVMDSEYGSGVGRSKKEAEQKAAAAAWKALE  228
            K F A V++  S  G+G GR+KKEAEQ AAAAA+  L+
Sbjct  193  KVFAARVLLSGSARGTGTGRTKKEAEQNAAAAAYTGLQ  230



Lambda     K      H
   0.315    0.133    0.378 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Effective search space used: 332206503090


  Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
    Posted date:  Sep 5, 2011  4:36 AM
  Number of letters in database: 5,219,829,388
  Number of sequences in database:  15,229,318



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40