BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv2948c Length=705 Score E Sequences producing significant alignments: (Bits) Value gi|15610085|ref|NP_217464.1| acyl-CoA synthetase [Mycobacterium ... 1419 0.0 gi|289448615|ref|ZP_06438359.1| polyketide synthase pks15 [Mycob... 1417 0.0 gi|289444508|ref|ZP_06434252.1| fatty-acid-CoA ligase fadD22 [My... 1416 0.0 gi|560509|gb|AAA50930.1| pks002a [Mycobacterium tuberculosis] 1415 0.0 gi|340627937|ref|YP_004746389.1| putative fatty-acid-CoA ligase ... 1407 0.0 gi|254552023|ref|ZP_05142470.1| acyl-CoA synthetase [Mycobacteri... 1263 0.0 gi|289763126|ref|ZP_06522504.1| fatty-acid-CoA ligase fadD22 [My... 1104 0.0 gi|15826965|ref|NP_301228.1| acyl-CoA synthetase [Mycobacterium ... 1045 0.0 gi|183981774|ref|YP_001850065.1| fatty-acid-CoA ligase FadD22 [M... 1031 0.0 gi|240171786|ref|ZP_04750445.1| acyl-CoA synthetase [Mycobacteri... 1030 0.0 gi|118617582|ref|YP_905914.1| acyl-CoA synthetase [Mycobacterium... 989 0.0 gi|183980136|ref|YP_001848427.1| polyketide synthase PKS [Mycoba... 849 0.0 gi|297560725|ref|YP_003679699.1| AMP-dependent synthetase and li... 335 2e-89 gi|297155049|gb|ADI04761.1| AMP-binding protein [Streptomyces bi... 317 3e-84 gi|29827718|ref|NP_822352.1| acyl-CoA synthase [Streptomyces ave... 314 4e-83 gi|290955412|ref|YP_003486594.1| AMP-binding protein [Streptomyc... 313 6e-83 gi|254383649|ref|ZP_04998998.1| acyl-CoA synthase [Streptomyces ... 311 2e-82 gi|288917259|ref|ZP_06411627.1| AMP-dependent synthetase and lig... 306 6e-81 gi|302553683|ref|ZP_07306025.1| dicarboxylate-CoA ligase PimA [S... 303 1e-79 gi|337769466|emb|CCB78179.1| Acyl-CoA synthase [Streptomyces cat... 295 2e-77 gi|134100572|ref|YP_001106233.1| acyl-CoA synthase [Saccharopoly... 281 3e-73 gi|254386312|ref|ZP_05001620.1| hypothetical protein SSAG_05942 ... 275 2e-71 gi|271965232|ref|YP_003339428.1| benzoate-coenzyme A ligase [Str... 275 2e-71 gi|317405901|gb|EFV86183.1| acyl-coenzyme A synthetase [Achromob... 261 3e-67 gi|338783457|gb|EGP47823.1| benzoate-coenzyme A ligase [Achromob... 254 3e-65 gi|116750059|ref|YP_846746.1| benzoate-CoA ligase family [Syntro... 252 1e-64 gi|256377631|ref|YP_003101291.1| AMP-dependent synthetase and li... 251 4e-64 gi|138895541|ref|YP_001125994.1| benzoate-CoA ligase [Geobacillu... 250 5e-64 gi|163857887|ref|YP_001632185.1| acyl-coenzyme A synthetase [Bor... 250 7e-64 gi|311108203|ref|YP_003981056.1| benzoate-coenzyme A ligase [Ach... 249 1e-63 gi|293607059|ref|ZP_06689402.1| benzoate-coenzyme A ligase [Achr... 248 3e-63 gi|299533431|ref|ZP_07046813.1| benzoate-CoA ligase family prote... 243 1e-61 gi|300245891|gb|ADJ94003.1| putative benzoate-CoA ligase BzlA [C... 242 2e-61 gi|194289443|ref|YP_002005350.1| benzoate-CoA ligase [Cupriavidu... 242 2e-61 gi|113867426|ref|YP_725915.1| benzoate-coenzyme A ligase [Ralsto... 242 2e-61 gi|94310169|ref|YP_583379.1| benzoate-CoA ligase family [Cupriav... 241 4e-61 gi|337279878|ref|YP_004619350.1| benzoate-CoA ligase [Ramlibacte... 241 4e-61 gi|85858651|ref|YP_460853.1| 4-hydroxybenzoate--CoA ligase / ben... 240 6e-61 gi|339325574|ref|YP_004685267.1| benzoate--CoA ligase BclA [Cupr... 239 9e-61 gi|261420205|ref|YP_003253887.1| benzoate-CoA ligase family [Geo... 239 1e-60 gi|56420526|ref|YP_147844.1| hypothetical protein GK1991 [Geobac... 239 1e-60 gi|300245667|gb|ADJ93891.1| putative benzoate-CoA ligase BzlA [C... 238 4e-60 gi|320355252|ref|YP_004196591.1| benzoate-CoA ligase [Desulfobul... 238 4e-60 gi|189425456|ref|YP_001952633.1| benzoate-CoA ligase [Geobacter ... 237 5e-60 gi|118579947|ref|YP_901197.1| benzoate-CoA ligase family [Peloba... 237 7e-60 gi|300246001|gb|ADJ94058.1| putative benzoate-CoA ligase BzlA [C... 236 1e-59 gi|90265799|dbj|BAE91925.1| benzoate-CoA ligase [Magnetospirillu... 236 1e-59 gi|83311968|ref|YP_422232.1| Acyl-coenzyme A synthetase/AMP-(fat... 236 1e-59 gi|221069666|ref|ZP_03545771.1| benzoate-CoA ligase family [Coma... 235 2e-59 gi|56478449|ref|YP_160038.1| benzoate-CoA ligase [Aromatoleum ar... 235 2e-59 >gi|15610085|ref|NP_217464.1| acyl-CoA synthetase [Mycobacterium tuberculosis H37Rv] gi|15842496|ref|NP_337533.1| acyl-CoA synthetase [Mycobacterium tuberculosis CDC1551] gi|31794124|ref|NP_856617.1| acyl-CoA synthetase [Mycobacterium bovis AF2122/97] 67 more sequence titles Length=705 Score = 1419 bits (3672), Expect = 0.0, Method: Compositional matrix adjust. Identities = 705/705 (100%), Positives = 705/705 (100%), Gaps = 0/705 (0%) Query 1 MRNGNLAGLLAEQASEAGWYDRPAFYAADVVTHGQIHDGAARLGEVLRNRGLSSGDRVLL 60 MRNGNLAGLLAEQASEAGWYDRPAFYAADVVTHGQIHDGAARLGEVLRNRGLSSGDRVLL Sbjct 1 MRNGNLAGLLAEQASEAGWYDRPAFYAADVVTHGQIHDGAARLGEVLRNRGLSSGDRVLL 60 Query 61 CLPDSPDLVQLLLACLARGVMAFLANPELHRDDHALAARNTEPALVVTSDALRDRFQPSR 120 CLPDSPDLVQLLLACLARGVMAFLANPELHRDDHALAARNTEPALVVTSDALRDRFQPSR Sbjct 61 CLPDSPDLVQLLLACLARGVMAFLANPELHRDDHALAARNTEPALVVTSDALRDRFQPSR 120 Query 121 VAEAAELMSEAARVAPGGYEPMGGDALAYATYTSGTTGPPKAAIHRHADPLTFVDAMCRK 180 VAEAAELMSEAARVAPGGYEPMGGDALAYATYTSGTTGPPKAAIHRHADPLTFVDAMCRK Sbjct 121 VAEAAELMSEAARVAPGGYEPMGGDALAYATYTSGTTGPPKAAIHRHADPLTFVDAMCRK 180 Query 181 ALRLTPEDTGLCSARMYFAYGLGNSVWFPLATGGSAVINSAPVTPEAAAILSARFGPSVL 240 ALRLTPEDTGLCSARMYFAYGLGNSVWFPLATGGSAVINSAPVTPEAAAILSARFGPSVL Sbjct 181 ALRLTPEDTGLCSARMYFAYGLGNSVWFPLATGGSAVINSAPVTPEAAAILSARFGPSVL 240 Query 241 YGVPNFFARVIDSCSPDSFRSLRCVVSAGEALELGLAERLMEFFGGIPILDGIGSTEVGQ 300 YGVPNFFARVIDSCSPDSFRSLRCVVSAGEALELGLAERLMEFFGGIPILDGIGSTEVGQ Sbjct 241 YGVPNFFARVIDSCSPDSFRSLRCVVSAGEALELGLAERLMEFFGGIPILDGIGSTEVGQ 300 Query 301 TFVSNRVDEWRLGTLGRVLPPYEIRVVAPDGTTAGPGVEGDLWVRGPAIAKGYWNRPDSP 360 TFVSNRVDEWRLGTLGRVLPPYEIRVVAPDGTTAGPGVEGDLWVRGPAIAKGYWNRPDSP Sbjct 301 TFVSNRVDEWRLGTLGRVLPPYEIRVVAPDGTTAGPGVEGDLWVRGPAIAKGYWNRPDSP 360 Query 361 VANEGWLDTRDRVCIDSDGWVTYRCRADDTEVIGGVNVDPREVERLIIEDEAVAEAAVVA 420 VANEGWLDTRDRVCIDSDGWVTYRCRADDTEVIGGVNVDPREVERLIIEDEAVAEAAVVA Sbjct 361 VANEGWLDTRDRVCIDSDGWVTYRCRADDTEVIGGVNVDPREVERLIIEDEAVAEAAVVA 420 Query 421 VRESTGASTLQAFLVATSGATIDGSVMRDLHRGLLNRLSAFKVPHRFAVVDRLPRTPNGK 480 VRESTGASTLQAFLVATSGATIDGSVMRDLHRGLLNRLSAFKVPHRFAVVDRLPRTPNGK Sbjct 421 VRESTGASTLQAFLVATSGATIDGSVMRDLHRGLLNRLSAFKVPHRFAVVDRLPRTPNGK 480 Query 481 LVRGALRKQSPTKPIWELSLTEPGSGVRAQRDDLSASNMTIAGGNDGGATLRERLVALRQ 540 LVRGALRKQSPTKPIWELSLTEPGSGVRAQRDDLSASNMTIAGGNDGGATLRERLVALRQ Sbjct 481 LVRGALRKQSPTKPIWELSLTEPGSGVRAQRDDLSASNMTIAGGNDGGATLRERLVALRQ 540 Query 541 ERQRLVVDAVCAEAAKMLGEPDPWSVDQDLAFSELGFDSQMTVTLCKRLAAVTGLRLPET 600 ERQRLVVDAVCAEAAKMLGEPDPWSVDQDLAFSELGFDSQMTVTLCKRLAAVTGLRLPET Sbjct 541 ERQRLVVDAVCAEAAKMLGEPDPWSVDQDLAFSELGFDSQMTVTLCKRLAAVTGLRLPET 600 Query 601 VGWDYGSISGLAQYLEAELAGGHGRLKSAGPVNSGATGLWAIEEQLNKVEELVAVIADGE 660 VGWDYGSISGLAQYLEAELAGGHGRLKSAGPVNSGATGLWAIEEQLNKVEELVAVIADGE Sbjct 601 VGWDYGSISGLAQYLEAELAGGHGRLKSAGPVNSGATGLWAIEEQLNKVEELVAVIADGE 660 Query 661 KQRVADRLRALLGTIAGSEAGLGKLIQAASTPDEIFQLIDSELGK 705 KQRVADRLRALLGTIAGSEAGLGKLIQAASTPDEIFQLIDSELGK Sbjct 661 KQRVADRLRALLGTIAGSEAGLGKLIQAASTPDEIFQLIDSELGK 705 >gi|289448615|ref|ZP_06438359.1| polyketide synthase pks15 [Mycobacterium tuberculosis CPHL_A] gi|289421573|gb|EFD18774.1| polyketide synthase pks15 [Mycobacterium tuberculosis CPHL_A] Length=705 Score = 1417 bits (3668), Expect = 0.0, Method: Compositional matrix adjust. Identities = 704/705 (99%), Positives = 705/705 (100%), Gaps = 0/705 (0%) Query 1 MRNGNLAGLLAEQASEAGWYDRPAFYAADVVTHGQIHDGAARLGEVLRNRGLSSGDRVLL 60 MRNGNLAGLLAEQASEAGWYDRPAFYAADVVTHGQIHDGAARLGEVLRNRGLSSGDRVLL Sbjct 1 MRNGNLAGLLAEQASEAGWYDRPAFYAADVVTHGQIHDGAARLGEVLRNRGLSSGDRVLL 60 Query 61 CLPDSPDLVQLLLACLARGVMAFLANPELHRDDHALAARNTEPALVVTSDALRDRFQPSR 120 CLPDSPDLVQLLLACLARGVMAFLANPELHRDDHALAARNTEPALVVTSDALRDRFQPSR Sbjct 61 CLPDSPDLVQLLLACLARGVMAFLANPELHRDDHALAARNTEPALVVTSDALRDRFQPSR 120 Query 121 VAEAAELMSEAARVAPGGYEPMGGDALAYATYTSGTTGPPKAAIHRHADPLTFVDAMCRK 180 VAEAAELMSEAARVAPGGYEPMGGDALAYATYTSGTTGPPKAAIHRHADPLTFVDAMCRK Sbjct 121 VAEAAELMSEAARVAPGGYEPMGGDALAYATYTSGTTGPPKAAIHRHADPLTFVDAMCRK 180 Query 181 ALRLTPEDTGLCSARMYFAYGLGNSVWFPLATGGSAVINSAPVTPEAAAILSARFGPSVL 240 ALRLTPEDTGLCSARMYFAYGLGNSVWFPLATGGSAVINSAPVTPEAAAILSARFGPSVL Sbjct 181 ALRLTPEDTGLCSARMYFAYGLGNSVWFPLATGGSAVINSAPVTPEAAAILSARFGPSVL 240 Query 241 YGVPNFFARVIDSCSPDSFRSLRCVVSAGEALELGLAERLMEFFGGIPILDGIGSTEVGQ 300 YGVPNFFARVIDSCSPDSFRSLRCVVSAGEALELGLAERLMEFFGGIPILDGIGSTEVGQ Sbjct 241 YGVPNFFARVIDSCSPDSFRSLRCVVSAGEALELGLAERLMEFFGGIPILDGIGSTEVGQ 300 Query 301 TFVSNRVDEWRLGTLGRVLPPYEIRVVAPDGTTAGPGVEGDLWVRGPAIAKGYWNRPDSP 360 TFVSNRVDEWRLGTLGRVLPPYEIRVVAPDGTTAGPGVEGDLWVRGPAIAKGYWNRPDSP Sbjct 301 TFVSNRVDEWRLGTLGRVLPPYEIRVVAPDGTTAGPGVEGDLWVRGPAIAKGYWNRPDSP 360 Query 361 VANEGWLDTRDRVCIDSDGWVTYRCRADDTEVIGGVNVDPREVERLIIEDEAVAEAAVVA 420 VANEGWLDTRDRVCIDSDGWVTYRCRADDTEVIGGVNVDPREVERLIIEDEAVAEAAVVA Sbjct 361 VANEGWLDTRDRVCIDSDGWVTYRCRADDTEVIGGVNVDPREVERLIIEDEAVAEAAVVA 420 Query 421 VRESTGASTLQAFLVATSGATIDGSVMRDLHRGLLNRLSAFKVPHRFAVVDRLPRTPNGK 480 VRESTGASTLQAFLVATSGATIDGSVMRDLHRGLLNRLSAFKVPHRFAVVDRLPRTPNGK Sbjct 421 VRESTGASTLQAFLVATSGATIDGSVMRDLHRGLLNRLSAFKVPHRFAVVDRLPRTPNGK 480 Query 481 LVRGALRKQSPTKPIWELSLTEPGSGVRAQRDDLSASNMTIAGGNDGGATLRERLVALRQ 540 LVRGALRKQSPTKPIWELSLTEPGSGVRAQRDDLSASNMTIAGGNDGGATLRERLVALRQ Sbjct 481 LVRGALRKQSPTKPIWELSLTEPGSGVRAQRDDLSASNMTIAGGNDGGATLRERLVALRQ 540 Query 541 ERQRLVVDAVCAEAAKMLGEPDPWSVDQDLAFSELGFDSQMTVTLCKRLAAVTGLRLPET 600 ERQRLVVDAVCAEAAKMLGEPDPWSVDQDLAFSELGFDSQMTVTLCKRLAAVTGLRLPET Sbjct 541 ERQRLVVDAVCAEAAKMLGEPDPWSVDQDLAFSELGFDSQMTVTLCKRLAAVTGLRLPET 600 Query 601 VGWDYGSISGLAQYLEAELAGGHGRLKSAGPVNSGATGLWAIEEQLNKVEELVAVIADGE 660 VGWDYGSISGLAQYLEAELAGGHGRLKSAGPVNSGATGLWAIEEQLNKVEELVAV+ADGE Sbjct 601 VGWDYGSISGLAQYLEAELAGGHGRLKSAGPVNSGATGLWAIEEQLNKVEELVAVVADGE 660 Query 661 KQRVADRLRALLGTIAGSEAGLGKLIQAASTPDEIFQLIDSELGK 705 KQRVADRLRALLGTIAGSEAGLGKLIQAASTPDEIFQLIDSELGK Sbjct 661 KQRVADRLRALLGTIAGSEAGLGKLIQAASTPDEIFQLIDSELGK 705 >gi|289444508|ref|ZP_06434252.1| fatty-acid-CoA ligase fadD22 [Mycobacterium tuberculosis T46] gi|289571141|ref|ZP_06451368.1| fatty-acid-CoA ligase fadD22 [Mycobacterium tuberculosis T17] gi|289751622|ref|ZP_06511000.1| fatty-acid-CoA ligase fadD22 [Mycobacterium tuberculosis T92] gi|289755063|ref|ZP_06514441.1| fatty-acid-CoA ligase FadD22 [Mycobacterium tuberculosis EAS054] gi|289417427|gb|EFD14667.1| fatty-acid-CoA ligase fadD22 [Mycobacterium tuberculosis T46] gi|289544895|gb|EFD48543.1| fatty-acid-CoA ligase fadD22 [Mycobacterium tuberculosis T17] gi|289692209|gb|EFD59638.1| fatty-acid-CoA ligase fadD22 [Mycobacterium tuberculosis T92] gi|289695650|gb|EFD63079.1| fatty-acid-CoA ligase FadD22 [Mycobacterium tuberculosis EAS054] Length=705 Score = 1416 bits (3666), Expect = 0.0, Method: Compositional matrix adjust. Identities = 704/705 (99%), Positives = 704/705 (99%), Gaps = 0/705 (0%) Query 1 MRNGNLAGLLAEQASEAGWYDRPAFYAADVVTHGQIHDGAARLGEVLRNRGLSSGDRVLL 60 MRNGNLAGLLAEQASEAGWYDRPAFYAADVVTHGQIHDGAARLGEVLRNRGLSSGDRVLL Sbjct 1 MRNGNLAGLLAEQASEAGWYDRPAFYAADVVTHGQIHDGAARLGEVLRNRGLSSGDRVLL 60 Query 61 CLPDSPDLVQLLLACLARGVMAFLANPELHRDDHALAARNTEPALVVTSDALRDRFQPSR 120 CLPDSPDLVQLLLACLARGVMAFLANPELHRDDHALAARNTEPALVVTSDALRDRFQPSR Sbjct 61 CLPDSPDLVQLLLACLARGVMAFLANPELHRDDHALAARNTEPALVVTSDALRDRFQPSR 120 Query 121 VAEAAELMSEAARVAPGGYEPMGGDALAYATYTSGTTGPPKAAIHRHADPLTFVDAMCRK 180 VAEAAELMSEAARVAPGGYEPMGGDALAYATYTSGTTGPPKAAIHRHADPLTFVDAMCRK Sbjct 121 VAEAAELMSEAARVAPGGYEPMGGDALAYATYTSGTTGPPKAAIHRHADPLTFVDAMCRK 180 Query 181 ALRLTPEDTGLCSARMYFAYGLGNSVWFPLATGGSAVINSAPVTPEAAAILSARFGPSVL 240 LRLTPEDTGLCSARMYFAYGLGNSVWFPLATGGSAVINSAPVTPEAAAILSARFGPSVL Sbjct 181 VLRLTPEDTGLCSARMYFAYGLGNSVWFPLATGGSAVINSAPVTPEAAAILSARFGPSVL 240 Query 241 YGVPNFFARVIDSCSPDSFRSLRCVVSAGEALELGLAERLMEFFGGIPILDGIGSTEVGQ 300 YGVPNFFARVIDSCSPDSFRSLRCVVSAGEALELGLAERLMEFFGGIPILDGIGSTEVGQ Sbjct 241 YGVPNFFARVIDSCSPDSFRSLRCVVSAGEALELGLAERLMEFFGGIPILDGIGSTEVGQ 300 Query 301 TFVSNRVDEWRLGTLGRVLPPYEIRVVAPDGTTAGPGVEGDLWVRGPAIAKGYWNRPDSP 360 TFVSNRVDEWRLGTLGRVLPPYEIRVVAPDGTTAGPGVEGDLWVRGPAIAKGYWNRPDSP Sbjct 301 TFVSNRVDEWRLGTLGRVLPPYEIRVVAPDGTTAGPGVEGDLWVRGPAIAKGYWNRPDSP 360 Query 361 VANEGWLDTRDRVCIDSDGWVTYRCRADDTEVIGGVNVDPREVERLIIEDEAVAEAAVVA 420 VANEGWLDTRDRVCIDSDGWVTYRCRADDTEVIGGVNVDPREVERLIIEDEAVAEAAVVA Sbjct 361 VANEGWLDTRDRVCIDSDGWVTYRCRADDTEVIGGVNVDPREVERLIIEDEAVAEAAVVA 420 Query 421 VRESTGASTLQAFLVATSGATIDGSVMRDLHRGLLNRLSAFKVPHRFAVVDRLPRTPNGK 480 VRESTGASTLQAFLVATSGATIDGSVMRDLHRGLLNRLSAFKVPHRFAVVDRLPRTPNGK Sbjct 421 VRESTGASTLQAFLVATSGATIDGSVMRDLHRGLLNRLSAFKVPHRFAVVDRLPRTPNGK 480 Query 481 LVRGALRKQSPTKPIWELSLTEPGSGVRAQRDDLSASNMTIAGGNDGGATLRERLVALRQ 540 LVRGALRKQSPTKPIWELSLTEPGSGVRAQRDDLSASNMTIAGGNDGGATLRERLVALRQ Sbjct 481 LVRGALRKQSPTKPIWELSLTEPGSGVRAQRDDLSASNMTIAGGNDGGATLRERLVALRQ 540 Query 541 ERQRLVVDAVCAEAAKMLGEPDPWSVDQDLAFSELGFDSQMTVTLCKRLAAVTGLRLPET 600 ERQRLVVDAVCAEAAKMLGEPDPWSVDQDLAFSELGFDSQMTVTLCKRLAAVTGLRLPET Sbjct 541 ERQRLVVDAVCAEAAKMLGEPDPWSVDQDLAFSELGFDSQMTVTLCKRLAAVTGLRLPET 600 Query 601 VGWDYGSISGLAQYLEAELAGGHGRLKSAGPVNSGATGLWAIEEQLNKVEELVAVIADGE 660 VGWDYGSISGLAQYLEAELAGGHGRLKSAGPVNSGATGLWAIEEQLNKVEELVAVIADGE Sbjct 601 VGWDYGSISGLAQYLEAELAGGHGRLKSAGPVNSGATGLWAIEEQLNKVEELVAVIADGE 660 Query 661 KQRVADRLRALLGTIAGSEAGLGKLIQAASTPDEIFQLIDSELGK 705 KQRVADRLRALLGTIAGSEAGLGKLIQAASTPDEIFQLIDSELGK Sbjct 661 KQRVADRLRALLGTIAGSEAGLGKLIQAASTPDEIFQLIDSELGK 705 >gi|560509|gb|AAA50930.1| pks002a [Mycobacterium tuberculosis] Length=705 Score = 1415 bits (3663), Expect = 0.0, Method: Compositional matrix adjust. Identities = 703/705 (99%), Positives = 705/705 (100%), Gaps = 0/705 (0%) Query 1 MRNGNLAGLLAEQASEAGWYDRPAFYAADVVTHGQIHDGAARLGEVLRNRGLSSGDRVLL 60 MRNGNLAGLLAEQASEAGWYDRPAFYAADVVTHGQIHDGAARLGEVLRNRGLSSGDRVLL Sbjct 1 MRNGNLAGLLAEQASEAGWYDRPAFYAADVVTHGQIHDGAARLGEVLRNRGLSSGDRVLL 60 Query 61 CLPDSPDLVQLLLACLARGVMAFLANPELHRDDHALAARNTEPALVVTSDALRDRFQPSR 120 CLPDSPDLVQLLLACLARGVMAFLANPELHRDDHALAARNTEPALVVTSDALRDRFQPSR Sbjct 61 CLPDSPDLVQLLLACLARGVMAFLANPELHRDDHALAARNTEPALVVTSDALRDRFQPSR 120 Query 121 VAEAAELMSEAARVAPGGYEPMGGDALAYATYTSGTTGPPKAAIHRHADPLTFVDAMCRK 180 VAEAAELMSEAARVAPGGYEPMGGDALAYATYTSGTTGPPKAAIHRHADPLTFVDAMCRK Sbjct 121 VAEAAELMSEAARVAPGGYEPMGGDALAYATYTSGTTGPPKAAIHRHADPLTFVDAMCRK 180 Query 181 ALRLTPEDTGLCSARMYFAYGLGNSVWFPLATGGSAVINSAPVTPEAAAILSARFGPSVL 240 ALRLTPEDTGLCSARMYFAYGLGNSVWFPLATGGSAVINSAPVTPEAAAILSARFGPSVL Sbjct 181 ALRLTPEDTGLCSARMYFAYGLGNSVWFPLATGGSAVINSAPVTPEAAAILSARFGPSVL 240 Query 241 YGVPNFFARVIDSCSPDSFRSLRCVVSAGEALELGLAERLMEFFGGIPILDGIGSTEVGQ 300 YGVPNFFARVIDSCSPDSFRSLRCVVSAGEALELGLAERLMEFFGGIPILDGIGSTEVGQ Sbjct 241 YGVPNFFARVIDSCSPDSFRSLRCVVSAGEALELGLAERLMEFFGGIPILDGIGSTEVGQ 300 Query 301 TFVSNRVDEWRLGTLGRVLPPYEIRVVAPDGTTAGPGVEGDLWVRGPAIAKGYWNRPDSP 360 TFVSNRVDEWRLGTLGRVLPPYEIRVVAPDGTTAGPGVEGDLWVRGPAIAKGYWNRPDSP Sbjct 301 TFVSNRVDEWRLGTLGRVLPPYEIRVVAPDGTTAGPGVEGDLWVRGPAIAKGYWNRPDSP 360 Query 361 VANEGWLDTRDRVCIDSDGWVTYRCRADDTEVIGGVNVDPREVERLIIEDEAVAEAAVVA 420 VANEGWLDTRDRVCIDSDGWVTYRCRADDTEVIGGVNVDPREVERLIIEDEAVAEAAVVA Sbjct 361 VANEGWLDTRDRVCIDSDGWVTYRCRADDTEVIGGVNVDPREVERLIIEDEAVAEAAVVA 420 Query 421 VRESTGASTLQAFLVATSGATIDGSVMRDLHRGLLNRLSAFKVPHRFAVVDRLPRTPNGK 480 VRESTGASTLQAFLVATSGATIDGSVMRDLHRGLLNRLSAFKVPHRFAVVDRLPRTPNGK Sbjct 421 VRESTGASTLQAFLVATSGATIDGSVMRDLHRGLLNRLSAFKVPHRFAVVDRLPRTPNGK 480 Query 481 LVRGALRKQSPTKPIWELSLTEPGSGVRAQRDDLSASNMTIAGGNDGGATLRERLVALRQ 540 LVRGAL++QSPTKPIWELSLTEPGSGVRAQRDDLSASNMTIAGGNDGGATLRERLVALRQ Sbjct 481 LVRGALQQQSPTKPIWELSLTEPGSGVRAQRDDLSASNMTIAGGNDGGATLRERLVALRQ 540 Query 541 ERQRLVVDAVCAEAAKMLGEPDPWSVDQDLAFSELGFDSQMTVTLCKRLAAVTGLRLPET 600 ERQRLVVDAVCAEAAKMLGEPDPWSVDQDLAFSELGFDSQMTVTLCKRLAAVTGLRLPET Sbjct 541 ERQRLVVDAVCAEAAKMLGEPDPWSVDQDLAFSELGFDSQMTVTLCKRLAAVTGLRLPET 600 Query 601 VGWDYGSISGLAQYLEAELAGGHGRLKSAGPVNSGATGLWAIEEQLNKVEELVAVIADGE 660 VGWDYGSISGLAQYLEAELAGGHGRLKSAGPVNSGATGLWAIEEQLNKVEELVAVIADGE Sbjct 601 VGWDYGSISGLAQYLEAELAGGHGRLKSAGPVNSGATGLWAIEEQLNKVEELVAVIADGE 660 Query 661 KQRVADRLRALLGTIAGSEAGLGKLIQAASTPDEIFQLIDSELGK 705 KQRVADRLRALLGTIAGSEAGLGKLIQAASTPDEIFQLIDSELGK Sbjct 661 KQRVADRLRALLGTIAGSEAGLGKLIQAASTPDEIFQLIDSELGK 705 >gi|340627937|ref|YP_004746389.1| putative fatty-acid-CoA ligase FADD22 [Mycobacterium canettii CIPT 140010059] gi|340006127|emb|CCC45299.1| putative fatty-acid-CoA ligase FADD22 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) [Mycobacterium canettii CIPT 140010059] Length=705 Score = 1407 bits (3642), Expect = 0.0, Method: Compositional matrix adjust. Identities = 700/705 (99%), Positives = 703/705 (99%), Gaps = 0/705 (0%) Query 1 MRNGNLAGLLAEQASEAGWYDRPAFYAADVVTHGQIHDGAARLGEVLRNRGLSSGDRVLL 60 MRNGNLAGLLAEQASEAGWYDRPAFYAADVVTHGQIHDGAARLGEVLRNRGLSSGDRVLL Sbjct 1 MRNGNLAGLLAEQASEAGWYDRPAFYAADVVTHGQIHDGAARLGEVLRNRGLSSGDRVLL 60 Query 61 CLPDSPDLVQLLLACLARGVMAFLANPELHRDDHALAARNTEPALVVTSDALRDRFQPSR 120 CLPDSPDLVQLLLACLARGVMAFLANPELHRDDHALA RNTEPALVVTSDALRDRFQPSR Sbjct 61 CLPDSPDLVQLLLACLARGVMAFLANPELHRDDHALAERNTEPALVVTSDALRDRFQPSR 120 Query 121 VAEAAELMSEAARVAPGGYEPMGGDALAYATYTSGTTGPPKAAIHRHADPLTFVDAMCRK 180 VAEAAELMSEAAR APGGYEP+GGDALAYATYTSGTTGPPKAAIHRHADPLTFVDAMCRK Sbjct 121 VAEAAELMSEAARGAPGGYEPVGGDALAYATYTSGTTGPPKAAIHRHADPLTFVDAMCRK 180 Query 181 ALRLTPEDTGLCSARMYFAYGLGNSVWFPLATGGSAVINSAPVTPEAAAILSARFGPSVL 240 ALRLTPEDTGLCSARMYFAYGLGNSVWFPLATGGSAVINSAPVTPEAAAILSARFGPSVL Sbjct 181 ALRLTPEDTGLCSARMYFAYGLGNSVWFPLATGGSAVINSAPVTPEAAAILSARFGPSVL 240 Query 241 YGVPNFFARVIDSCSPDSFRSLRCVVSAGEALELGLAERLMEFFGGIPILDGIGSTEVGQ 300 YGVPNFFARVIDSC+PDSFRSLRCVVSAGEALELGLAERLMEFFGGIPILDGIGSTEVGQ Sbjct 241 YGVPNFFARVIDSCTPDSFRSLRCVVSAGEALELGLAERLMEFFGGIPILDGIGSTEVGQ 300 Query 301 TFVSNRVDEWRLGTLGRVLPPYEIRVVAPDGTTAGPGVEGDLWVRGPAIAKGYWNRPDSP 360 TFVSNRVDEWRLGTLGRVLPPYEIRVVAPDGTTAGPGVEGDLWVRGPAIAKGYWNRPDSP Sbjct 301 TFVSNRVDEWRLGTLGRVLPPYEIRVVAPDGTTAGPGVEGDLWVRGPAIAKGYWNRPDSP 360 Query 361 VANEGWLDTRDRVCIDSDGWVTYRCRADDTEVIGGVNVDPREVERLIIEDEAVAEAAVVA 420 VANEGWLDTRDRVCIDSDGWVTYRCRADDTEVIGGVNVDPREVERLIIED+AVAEAAVVA Sbjct 361 VANEGWLDTRDRVCIDSDGWVTYRCRADDTEVIGGVNVDPREVERLIIEDDAVAEAAVVA 420 Query 421 VRESTGASTLQAFLVATSGATIDGSVMRDLHRGLLNRLSAFKVPHRFAVVDRLPRTPNGK 480 VRESTGASTLQAFLVATSGATIDGSVMRDLHRGLLNRLSAFKVPHRFAVVDRLPRTPNGK Sbjct 421 VRESTGASTLQAFLVATSGATIDGSVMRDLHRGLLNRLSAFKVPHRFAVVDRLPRTPNGK 480 Query 481 LVRGALRKQSPTKPIWELSLTEPGSGVRAQRDDLSASNMTIAGGNDGGATLRERLVALRQ 540 LVRGALRKQSPTKPIWELSLTEPGSGVRAQRDDLSASNMTIAGGNDGGATLRERLVALRQ Sbjct 481 LVRGALRKQSPTKPIWELSLTEPGSGVRAQRDDLSASNMTIAGGNDGGATLRERLVALRQ 540 Query 541 ERQRLVVDAVCAEAAKMLGEPDPWSVDQDLAFSELGFDSQMTVTLCKRLAAVTGLRLPET 600 ERQRLVVDAVCAEAAKMLGEPDPWSVDQDLAFSELGFDSQMTVTLCKRLAAVTGLRLPET Sbjct 541 ERQRLVVDAVCAEAAKMLGEPDPWSVDQDLAFSELGFDSQMTVTLCKRLAAVTGLRLPET 600 Query 601 VGWDYGSISGLAQYLEAELAGGHGRLKSAGPVNSGATGLWAIEEQLNKVEELVAVIADGE 660 VGWDYGSISGLAQYLEAELAGGHGRLKSAGPVNSGATGLWAIEEQLNKVEELVAVIADGE Sbjct 601 VGWDYGSISGLAQYLEAELAGGHGRLKSAGPVNSGATGLWAIEEQLNKVEELVAVIADGE 660 Query 661 KQRVADRLRALLGTIAGSEAGLGKLIQAASTPDEIFQLIDSELGK 705 KQRVADRLRALLGTIAGSEAGLGKLIQAASTPDEIFQLIDSELGK Sbjct 661 KQRVADRLRALLGTIAGSEAGLGKLIQAASTPDEIFQLIDSELGK 705 >gi|254552023|ref|ZP_05142470.1| acyl-CoA synthetase [Mycobacterium tuberculosis '98-R604 INH-RIF-EM'] Length=680 Score = 1263 bits (3267), Expect = 0.0, Method: Compositional matrix adjust. Identities = 651/679 (96%), Positives = 654/679 (97%), Gaps = 4/679 (0%) Query 1 MRNGNLAGLLAEQASEAGWYDRPAFYAADVVTHGQIHDGAARLGEVLRNRGLSSGDRVLL 60 MRNGNLAGLLAEQASEAGWYDRPAFYAADVVTHGQIHDGAARLGEVLRNRGLSSGDRVLL Sbjct 1 MRNGNLAGLLAEQASEAGWYDRPAFYAADVVTHGQIHDGAARLGEVLRNRGLSSGDRVLL 60 Query 61 CLPDSPDLVQLLLACLARGVMAFLANPELHRDDHALAARNTEPALVVTSDALRDRFQPSR 120 CLPDSPDLVQLLLACLARGVMAFLANPELHRDDHALAARNTEPALVVTSDALRDRFQPSR Sbjct 61 CLPDSPDLVQLLLACLARGVMAFLANPELHRDDHALAARNTEPALVVTSDALRDRFQPSR 120 Query 121 VAEAAELMSEAARVAPGGYEPMGGDALAYATYTSGTTGPPKAAIHRHADPLTFVDAMCRK 180 VAEAAELMSEAARVAPGGYEPMGGDALAYATYTSGTTGPPKAAIHRHADPLTFVDAMCRK Sbjct 121 VAEAAELMSEAARVAPGGYEPMGGDALAYATYTSGTTGPPKAAIHRHADPLTFVDAMCRK 180 Query 181 ALRLTPEDTGLCSARMYFAYGLGNSVWFPLATGGSAVINSAPVTPEAAAILSARFGPSVL 240 ALRLTPEDTGLCSARMYFAYGLGNSVWFPLATGGSAVINSAPVTPEAAAILSARFGPSVL Sbjct 181 ALRLTPEDTGLCSARMYFAYGLGNSVWFPLATGGSAVINSAPVTPEAAAILSARFGPSVL 240 Query 241 YGVPNFFARVIDSCSPDSFRSLRCVVSAGEALELGLAERLMEFFGGIPILDGIGSTEVGQ 300 YGVPNFFARVIDSCSPDSFRSLRCVVSAGEALELGLAERLMEFFGGIPILDGIGSTEVGQ Sbjct 241 YGVPNFFARVIDSCSPDSFRSLRCVVSAGEALELGLAERLMEFFGGIPILDGIGSTEVGQ 300 Query 301 TFVSNRVDEWRLGTLGRVLPPYEIRVVAPDGTTAGPGVEGDLWVRGPAIAKGYWNRPDSP 360 TFVSNRVDEWRLGTLGRVLPPYEIRVVAPDGTTAGPGVEGDLWVRGPAIAKGYWNRPDSP Sbjct 301 TFVSNRVDEWRLGTLGRVLPPYEIRVVAPDGTTAGPGVEGDLWVRGPAIAKGYWNRPDSP 360 Query 361 VANEGWLDTRDRVCIDSDGWVTYRCRADDTEVIGGVNVDPREVERLIIEDEAVAEAAVVA 420 VANEGWLDTRDRVCIDSDGWVTYRCRADDTEVIGGVNVDPREVERLIIEDEAVAEAAVVA Sbjct 361 VANEGWLDTRDRVCIDSDGWVTYRCRADDTEVIGGVNVDPREVERLIIEDEAVAEAAVVA 420 Query 421 VRESTGASTLQAFLVATSGATIDGSVMRDLHRGLLNRLSAFKVPHRFAVVDRLPRTPNGK 480 VRESTGASTLQAFLVATSGATIDGSVMRDLHRGLLNRLSAFKVPHRFAVVDRLPRTPNGK Sbjct 421 VRESTGASTLQAFLVATSGATIDGSVMRDLHRGLLNRLSAFKVPHRFAVVDRLPRTPNGK 480 Query 481 LVRGALRKQSPTKPIWELSLTEPGSGVRAQRDDLSASNMTIAGGNDGGATLRERLVALRQ 540 LVRGALRKQSPTKPIWELSLTEPGSGVRAQRDDLSASNMTIAGGNDGGATLRERLVALRQ Sbjct 481 LVRGALRKQSPTKPIWELSLTEPGSGVRAQRDDLSASNMTIAGGNDGGATLRERLVALRQ 540 Query 541 ERQRLVVDAVCAEAAKMLGEPDPWSVDQDLAFSELGFDSQMTVTLCKRLAAVTGLRLPET 600 ERQRLVVDAVCAEAAKMLGEPDPWSVDQDLAFSELGFDSQMTVTLCKRLAAVTGLRLPET Sbjct 541 ERQRLVVDAVCAEAAKMLGEPDPWSVDQDLAFSELGFDSQMTVTLCKRLAAVTGLRLPET 600 Query 601 VGWDYGSISGLAQYLEAELAGGHGRLKSAGPVNSGATGLWAIEEQLNKVEELVAVIADGE 660 VGWDYGSISGLAQYLEAELAGG G V + L + +KVEEL D E Sbjct 601 VGWDYGSISGLAQYLEAELAGGPW-FDDPGVVIAARRSL--ASKSSDKVEELCR-HRDRE 656 Query 661 KQRVADRLRALLGTIAGSE 679 KQRVADRLRALLGTIAGSE Sbjct 657 KQRVADRLRALLGTIAGSE 675 >gi|289763126|ref|ZP_06522504.1| fatty-acid-CoA ligase fadD22 [Mycobacterium tuberculosis GM 1503] gi|289710632|gb|EFD74648.1| fatty-acid-CoA ligase fadD22 [Mycobacterium tuberculosis GM 1503] Length=558 Score = 1104 bits (2855), Expect = 0.0, Method: Compositional matrix adjust. Identities = 547/547 (100%), Positives = 547/547 (100%), Gaps = 0/547 (0%) Query 1 MRNGNLAGLLAEQASEAGWYDRPAFYAADVVTHGQIHDGAARLGEVLRNRGLSSGDRVLL 60 MRNGNLAGLLAEQASEAGWYDRPAFYAADVVTHGQIHDGAARLGEVLRNRGLSSGDRVLL Sbjct 1 MRNGNLAGLLAEQASEAGWYDRPAFYAADVVTHGQIHDGAARLGEVLRNRGLSSGDRVLL 60 Query 61 CLPDSPDLVQLLLACLARGVMAFLANPELHRDDHALAARNTEPALVVTSDALRDRFQPSR 120 CLPDSPDLVQLLLACLARGVMAFLANPELHRDDHALAARNTEPALVVTSDALRDRFQPSR Sbjct 61 CLPDSPDLVQLLLACLARGVMAFLANPELHRDDHALAARNTEPALVVTSDALRDRFQPSR 120 Query 121 VAEAAELMSEAARVAPGGYEPMGGDALAYATYTSGTTGPPKAAIHRHADPLTFVDAMCRK 180 VAEAAELMSEAARVAPGGYEPMGGDALAYATYTSGTTGPPKAAIHRHADPLTFVDAMCRK Sbjct 121 VAEAAELMSEAARVAPGGYEPMGGDALAYATYTSGTTGPPKAAIHRHADPLTFVDAMCRK 180 Query 181 ALRLTPEDTGLCSARMYFAYGLGNSVWFPLATGGSAVINSAPVTPEAAAILSARFGPSVL 240 ALRLTPEDTGLCSARMYFAYGLGNSVWFPLATGGSAVINSAPVTPEAAAILSARFGPSVL Sbjct 181 ALRLTPEDTGLCSARMYFAYGLGNSVWFPLATGGSAVINSAPVTPEAAAILSARFGPSVL 240 Query 241 YGVPNFFARVIDSCSPDSFRSLRCVVSAGEALELGLAERLMEFFGGIPILDGIGSTEVGQ 300 YGVPNFFARVIDSCSPDSFRSLRCVVSAGEALELGLAERLMEFFGGIPILDGIGSTEVGQ Sbjct 241 YGVPNFFARVIDSCSPDSFRSLRCVVSAGEALELGLAERLMEFFGGIPILDGIGSTEVGQ 300 Query 301 TFVSNRVDEWRLGTLGRVLPPYEIRVVAPDGTTAGPGVEGDLWVRGPAIAKGYWNRPDSP 360 TFVSNRVDEWRLGTLGRVLPPYEIRVVAPDGTTAGPGVEGDLWVRGPAIAKGYWNRPDSP Sbjct 301 TFVSNRVDEWRLGTLGRVLPPYEIRVVAPDGTTAGPGVEGDLWVRGPAIAKGYWNRPDSP 360 Query 361 VANEGWLDTRDRVCIDSDGWVTYRCRADDTEVIGGVNVDPREVERLIIEDEAVAEAAVVA 420 VANEGWLDTRDRVCIDSDGWVTYRCRADDTEVIGGVNVDPREVERLIIEDEAVAEAAVVA Sbjct 361 VANEGWLDTRDRVCIDSDGWVTYRCRADDTEVIGGVNVDPREVERLIIEDEAVAEAAVVA 420 Query 421 VRESTGASTLQAFLVATSGATIDGSVMRDLHRGLLNRLSAFKVPHRFAVVDRLPRTPNGK 480 VRESTGASTLQAFLVATSGATIDGSVMRDLHRGLLNRLSAFKVPHRFAVVDRLPRTPNGK Sbjct 421 VRESTGASTLQAFLVATSGATIDGSVMRDLHRGLLNRLSAFKVPHRFAVVDRLPRTPNGK 480 Query 481 LVRGALRKQSPTKPIWELSLTEPGSGVRAQRDDLSASNMTIAGGNDGGATLRERLVALRQ 540 LVRGALRKQSPTKPIWELSLTEPGSGVRAQRDDLSASNMTIAGGNDGGATLRERLVALRQ Sbjct 481 LVRGALRKQSPTKPIWELSLTEPGSGVRAQRDDLSASNMTIAGGNDGGATLRERLVALRQ 540 Query 541 ERQRLVV 547 ERQRLVV Sbjct 541 ERQRLVV 547 >gi|15826965|ref|NP_301228.1| acyl-CoA synthetase [Mycobacterium leprae TN] gi|221229443|ref|YP_002502859.1| acyl-CoA synthetase [Mycobacterium leprae Br4923] gi|13092512|emb|CAC29642.1| putative acyl-CoA synthetase [Mycobacterium leprae] gi|219932550|emb|CAR70227.1| putative acyl-CoA synthetase [Mycobacterium leprae Br4923] Length=707 Score = 1045 bits (2702), Expect = 0.0, Method: Compositional matrix adjust. Identities = 535/705 (76%), Positives = 603/705 (86%), Gaps = 2/705 (0%) Query 1 MRNGNLAGLLAEQASEAGWYDRPAFYAADVVTHGQIHDGAARLGEVLRNRGLSSGDRVLL 60 MR+ NLA LLA QA+EAGWYD+PA++A DVVTHGQIHDGA RLGEVLRNRGLS+GDRVLL Sbjct 1 MRSENLAALLARQAAEAGWYDKPAYFAPDVVTHGQIHDGAVRLGEVLRNRGLSAGDRVLL 60 Query 61 CLPDSPDLVQLLLACLARGVMAFLANPELHRDDHALAARNTEPALVVTSDALRDRFQPSR 120 CLPDSPDLVQLLLACLARG+MAFLANPELHRDD+A R+T ALV+T+ +LRDRFQ S Sbjct 61 CLPDSPDLVQLLLACLARGIMAFLANPELHRDDYAFPERDTAAALVITNGSLRDRFQSSN 120 Query 121 VAEAAELMSEAARVAPGGYEPMGGDALAYATYTSGTTGPPKAAIHRHADPLTFVDAMCRK 180 V E AEL+S+A RV P YEP+ GDA A+ATYTSGTTG PKAAIHRHADP TFVDAMCRK Sbjct 121 VVEPAELLSDATRVEPSDYEPVSGDAYAFATYTSGTTGKPKAAIHRHADPFTFVDAMCRK 180 Query 181 ALRLTPEDTGLCSARMYFAYGLGNSVWFPLATGGSAVINSAPVTPEAAAILSARFGPSVL 240 ALRLTP+D GLCSARMYFAYGLGNSVWFPLATGGSAVI+S PV+ E+AA+LS RF PSVL Sbjct 181 ALRLTPQDIGLCSARMYFAYGLGNSVWFPLATGGSAVISSVPVSAESAAMLSTRFEPSVL 240 Query 241 YGVPNFFARVIDSCSPDSFRSLRCVVSAGEALELGLAERLMEFFGGIPILDGIGSTEVGQ 300 YGVP+FFARV+ +CSPDSFRSLRCVV+AGEALE LAERL+EFFGGIPILDGIGS+EVGQ Sbjct 241 YGVPSFFARVVGACSPDSFRSLRCVVTAGEALEPALAERLVEFFGGIPILDGIGSSEVGQ 300 Query 301 TFVSNRVDEWRLGTLGRVLPPYEIRVVAPDGTTAGPGVEGDLWVRGPAIAKGYWNRPDSP 360 TFVSN VD+WR+GTLG+VLPPYEIRVVAPDG TAG G+EG+LWVRGP+IA+ YWNRPDS Sbjct 301 TFVSNSVDDWRVGTLGKVLPPYEIRVVAPDGATAGSGIEGNLWVRGPSIAQSYWNRPDSL 360 Query 361 VANEGWLDTRDRVCIDSDGWVTYRCRADDTEVIGGVNVDPREVERLIIEDEAVAEAAVVA 420 + N WL+TRDRV ID DGWVTY CRADDTE++GGVN++PREVERLIIE +AVAEAAVV Sbjct 361 LENGDWLNTRDRVRIDGDGWVTYGCRADDTEIVGGVNINPREVERLIIEADAVAEAAVVG 420 Query 421 VRESTGASTLQAFLVATSGATIDGSVMRDLHRGLLNRLSAFKVPHRFAVVDRLPRTPNGK 480 VRE TGASTLQAFLV GA ID SVMRD+HR LL +L+AFKVPHRFA+++RLPR+ NGK Sbjct 421 VREFTGASTLQAFLVPAVGAFIDESVMRDVHRRLLTQLTAFKVPHRFAIIERLPRSTNGK 480 Query 481 LVRGALRKQSPTKPIWELSLTEPGSGVRAQRDDLSASN--MTIAGGNDGGATLRERLVAL 538 L+R LR QSPTKPIWELSLTE S +AQ D ASN A G+ GATL++RL AL Sbjct 481 LLRNVLRAQSPTKPIWELSLTESQSATKAQLDGRPASNAHAQAAVGHAAGATLKQRLSAL 540 Query 539 RQERQRLVVDAVCAEAAKMLGEPDPWSVDQDLAFSELGFDSQMTVTLCKRLAAVTGLRLP 598 +QER+RLVV+AVCAEA KMLGE DP +++DLAFS+LGFDSQMTVTLC RLA VTGLRLP Sbjct 541 QQERERLVVEAVCAEAVKMLGESDPGLINRDLAFSDLGFDSQMTVTLCNRLAVVTGLRLP 600 Query 599 ETVGWDYGSISGLAQYLEAELAGGHGRLKSAGPVNSGATGLWAIEEQLNKVEELVAVIAD 658 ETVGWDYGSISGL++YLEAEL+G R ++ NSGA GL I+E+L KVEE+V I Sbjct 601 ETVGWDYGSISGLSRYLEAELSGVRSRPETPLSANSGAKGLSPIDEELKKVEEMVVAIGA 660 Query 659 GEKQRVADRLRALLGTIAGSEAGLGKLIQAASTPDEIFQLIDSEL 703 EKQRVADRLRALLG I EAGL K IQAASTPDEIFQLIDSEL Sbjct 661 SEKQRVADRLRALLGIIVDGEAGLSKRIQAASTPDEIFQLIDSEL 705 >gi|183981774|ref|YP_001850065.1| fatty-acid-CoA ligase FadD22 [Mycobacterium marinum M] gi|327488112|sp|B2HIL6.1|FAA22_MYCMM RecName: Full=p-hydroxybenzoic acid--AMP ligase FadD22; Short=p-HB--AMP ligase FadD22; AltName: Full=p-hydroxybenzoic acid-AMP synthetase; Short=p-HB-AMP synthetase gi|183175100|gb|ACC40210.1| fatty-acid-CoA ligase FadD22 [Mycobacterium marinum M] Length=702 Score = 1031 bits (2665), Expect = 0.0, Method: Compositional matrix adjust. Identities = 526/705 (75%), Positives = 588/705 (84%), Gaps = 4/705 (0%) Query 1 MRNGNLAGLLAEQASEAGWYDRPAFYAADVVTHGQIHDGAARLGEVLRNRGLSSGDRVLL 60 MRN N+AGLLAE+ASEAGW D+PA+YA DVVTHGQIHDGAARLG VL NRGL GDRVLL Sbjct 1 MRNENVAGLLAERASEAGWTDQPAYYAPDVVTHGQIHDGAARLGAVLANRGLCRGDRVLL 60 Query 61 CLPDSPDLVQLLLACLARGVMAFLANPELHRDDHALAARNTEPALVVTSDALRDRFQPSR 120 C+PDSP+LVQ+LLACLARG++AFLANPELHRDDHA R+T+ ALV+TS L DRF PS Sbjct 61 CMPDSPELVQVLLACLARGILAFLANPELHRDDHAFQERDTQAALVITSGPLCDRFAPST 120 Query 121 VAEAAELMSEAARVAPGGYEPMGGDALAYATYTSGTTGPPKAAIHRHADPLTFVDAMCRK 180 V +AA+L SEAARV P YE +GGDA AYATYTSGTTGPPKAAIHRH D FV+AMCR Sbjct 121 VVDAADLFSEAARVGPADYEILGGDAAAYATYTSGTTGPPKAAIHRHCDVFAFVEAMCRN 180 Query 181 ALRLTPEDTGLCSARMYFAYGLGNSVWFPLATGGSAVINSAPVTPEAAAILSARFGPSVL 240 ALRLTP D GL SARMYFAYGLGNSVWFPLATG SAV+N PV E AA LSARF PSVL Sbjct 181 ALRLTPADIGLSSARMYFAYGLGNSVWFPLATGSSAVVNPLPVGAEVAATLSARFEPSVL 240 Query 241 YGVPNFFARVIDSCSPDSFRSLRCVVSAGEALELGLAERLMEFFGGIPILDGIGSTEVGQ 300 YGVPNFFARV+D+CS DSFRS+RCVVSAGEALE+GLAERL EFFGGIPILDG+GSTEVGQ Sbjct 241 YGVPNFFARVVDACSADSFRSVRCVVSAGEALEVGLAERLTEFFGGIPILDGVGSTEVGQ 300 Query 301 TFVSNRVDEWRLGTLGRVLPPYEIRVVAPDGTTAGPGVEGDLWVRGPAIAKGYWNRPDSP 360 TFVSN VDEWR G+LG+VLPPY+IRVVAPDG AGPGVEGDLWVRGP+IA+ YWN P+ Sbjct 301 TFVSNTVDEWRPGSLGKVLPPYQIRVVAPDGAAAGPGVEGDLWVRGPSIAESYWNWPEPL 360 Query 361 VANEGWLDTRDRVCIDSDGWVTYRCRADDTEVIGGVNVDPREVERLIIEDEAVAEAAVVA 420 + +EGWLDTRDRVCID DGWVTY CRADDTE++G VN++PRE+ERLI+E++AVAE AVV Sbjct 361 LTDEGWLDTRDRVCIDDDGWVTYACRADDTEIVGAVNINPREIERLIVEEDAVAEVAVVG 420 Query 421 VRESTGASTLQAFLVATSGATIDGSVMRDLHRGLLNRLSAFKVPHRFAVVDRLPRTPNGK 480 V+E+TGASTLQAFLV S IDGSVMRD+HR LL RLSAFKVPHRFAVV+RLPRT NGK Sbjct 421 VKEATGASTLQAFLVPASAEGIDGSVMRDIHRRLLTRLSAFKVPHRFAVVERLPRTANGK 480 Query 481 LVRGALRKQSPTKPIWELSLTEPGSGVRAQRDDLSASNMTIAGGNDGGATLRERLVALRQ 540 L+R ALR Q+P KPIWEL+ E SG Q DD SAS + ++G + +L+ERL AL+Q Sbjct 481 LLRSALRGQTPAKPIWELASAEHRSGAPGQLDDQSASAL-VSGSRE--VSLKERLAALQQ 537 Query 541 ERQRLVVDAVCAEAAKMLGEPDPWSVDQDLAFSELGFDSQMTVTLCKRLAAVTGLRLPET 600 ER RLV+DAVC E AKMLGEPDP SV++DLAFSELGFDSQMTV LC RLAA TGLR+PET Sbjct 538 ERHRLVLDAVCGETAKMLGEPDPRSVNRDLAFSELGFDSQMTVELCHRLAAATGLRVPET 597 Query 601 VGWDYGSISGLAQYLEAELAGGHGRLKSAGPVNSGATGLWAIEEQLNKVEELVAVIADGE 660 VGWDYGSISGLAQYLEAEL+G R+ SGA L IE QLNKVEEL A IADGE Sbjct 598 VGWDYGSISGLAQYLEAELSGADRRVTPQS-ARSGARALPLIEAQLNKVEELTAAIADGE 656 Query 661 KQRVADRLRALLGTIAGSEAGLGKLIQAASTPDEIFQLIDSELGK 705 K RVA+RLRALLGTI + G+ I AASTPDEIFQLIDSE G+ Sbjct 657 KPRVAERLRALLGTITEGQEHWGQRIAAASTPDEIFQLIDSEFGE 701 >gi|240171786|ref|ZP_04750445.1| acyl-CoA synthetase [Mycobacterium kansasii ATCC 12478] Length=704 Score = 1030 bits (2664), Expect = 0.0, Method: Compositional matrix adjust. Identities = 525/706 (75%), Positives = 589/706 (84%), Gaps = 4/706 (0%) Query 1 MRNGNLAGLLAEQASEAGWYDRPAFYAADVVTHGQIHDGAARLGEVLRNRGLSSGDRVLL 60 MRNGNLAG LAE+ASEAGWYDRPA+YA ++VTHGQIHDGAARL VL+ RGL +GDRVLL Sbjct 1 MRNGNLAGFLAERASEAGWYDRPAYYAPEIVTHGQIHDGAARLAHVLQRRGLGTGDRVLL 60 Query 61 CLPDSPDLVQLLLACLARGVMAFLANPELHRDDHALAARNTEPALVVTSDALRDRFQPSR 120 CLPDSP+LVQLLLACLARGVMAFLANPELHRDDHA R+TEPALVVTS L RF+PSR Sbjct 61 CLPDSPELVQLLLACLARGVMAFLANPELHRDDHAFLERDTEPALVVTSGPLCGRFRPSR 120 Query 121 VAEAAELMSEAARVAPGGYEPMGGDALAYATYTSGTTGPPKAAIHRHADPLTFVDAMCRK 180 V +AAEL+S AAR P YE +G DA AYATYTSGTTGPPKAAIHRHADPLTFVDAMC + Sbjct 121 VVDAAELLSAAARAEPAEYEQLGRDADAYATYTSGTTGPPKAAIHRHADPLTFVDAMCHQ 180 Query 181 ALRLTPEDTGLCSARMYFAYGLGNSVWFPLATGGSAVINSAPVTPEAAAILSARFGPSVL 240 ALRLT DTGL +ARMYFAYGLGNSVWFPLATGGSAVIN PV E AA L RF PSVL Sbjct 181 ALRLTAHDTGLSTARMYFAYGLGNSVWFPLATGGSAVINPLPVGAEMAATLCERFEPSVL 240 Query 241 YGVPNFFARVIDSCSPDSFRSLRCVVSAGEALELGLAERLMEFFGGIPILDGIGSTEVGQ 300 YGVPNFFARV+D+CS +SFR+LRC+VSAGEAL++GLAERL+EFFGGIPILDGIGSTEVGQ Sbjct 241 YGVPNFFARVVDTCSSESFRALRCIVSAGEALDMGLAERLIEFFGGIPILDGIGSTEVGQ 300 Query 301 TFVSNRVDEWRLGTLGRVLPPYEIRVVAPDGTTAGPGVEGDLWVRGPAIAKGYWNRPDSP 360 TFVSN VDEWR GTLG+ LPPYEIRV+ PDG A PGV+G+LWVRGP+IA GYWN PD Sbjct 301 TFVSNTVDEWRPGTLGKALPPYEIRVLGPDGAPAEPGVDGNLWVRGPSIATGYWNCPDPI 360 Query 361 VANEGWLDTRDRVCIDSDGWVTYRCRADDTEVIGGVNVDPREVERLIIEDEAVAEAAVVA 420 + +GWLDTRD V +D++GWV+YRCRADDTE++G VNV+PREVERL+ E +AVAE AVV Sbjct 361 LEEDGWLDTRDTVRVDAEGWVSYRCRADDTEIVGAVNVNPREVERLVAEHDAVAEVAVVG 420 Query 421 VRESTGASTLQAFLVATSGATIDGSVMRDLHRGLLNRLSAFKVPHRFAVVDRLPRTPNGK 480 V+ESTGAS LQAFLV T A ID SVMRD+HRGLL RLSAFKVPHR AVV+RLPRT NGK Sbjct 421 VKESTGASALQAFLVPTGHAVIDESVMRDIHRGLLTRLSAFKVPHRLAVVERLPRTANGK 480 Query 481 LVRGALRKQSPTKPIWELSLTEPGSGVRAQRDDLSASNMTIAGGNDGGATLRERLVALRQ 540 L+R ALR +SP KPIWELS +P Q D+ A+ T+A G+ G TL+ERL AL+Q Sbjct 481 LLRSALRAESPAKPIWELSSVQPRPDADPQHDNRPAAPRTVA-GHAGEVTLKERLAALQQ 539 Query 541 ERQRLVVDAVCAEAAKMLGEPDPWSVDQDLAFSELGFDSQMTVTLCKRLAAVTGLRLPET 600 ER RLVV+AV AEAAKMLGEPDP S+D+DLAFSELGFDSQMTV LC RLAA TGLRLPET Sbjct 540 ERHRLVVEAVSAEAAKMLGEPDPQSLDRDLAFSELGFDSQMTVVLCHRLAAATGLRLPET 599 Query 601 VGWDYGSISGLAQYLEAELAGGHGRLKSAG-PVNSGATGLWAIEEQLNKVEELVAVIADG 659 VGWDYGSISGLAQYLEAEL+GG R + P N A G ++E+L +++ELV I DG Sbjct 600 VGWDYGSISGLAQYLEAELSGGDRRAGAMTLPANIDAKG--RVDEELKRIDELVLTIGDG 657 Query 660 EKQRVADRLRALLGTIAGSEAGLGKLIQAASTPDEIFQLIDSELGK 705 EKQRVADRLRA+LGTI + LGK IQ ASTPDEIFQLIDSELG+ Sbjct 658 EKQRVADRLRAILGTITDAGDRLGKRIQDASTPDEIFQLIDSELGE 703 >gi|118617582|ref|YP_905914.1| acyl-CoA synthetase [Mycobacterium ulcerans Agy99] gi|118569692|gb|ABL04443.1| fatty-acid-CoA ligase FadD22 [Mycobacterium ulcerans Agy99] Length=702 Score = 989 bits (2556), Expect = 0.0, Method: Compositional matrix adjust. Identities = 520/705 (74%), Positives = 582/705 (83%), Gaps = 4/705 (0%) Query 1 MRNGNLAGLLAEQASEAGWYDRPAFYAADVVTHGQIHDGAARLGEVLRNRGLSSGDRVLL 60 MRN N+AGLLAE+ASEAGW D+PA+YA DVVTHGQIHDGAARLG VL NRGL GDRVLL Sbjct 1 MRNENVAGLLAERASEAGWTDQPAYYAPDVVTHGQIHDGAARLGAVLANRGLCRGDRVLL 60 Query 61 CLPDSPDLVQLLLACLARGVMAFLANPELHRDDHALAARNTEPALVVTSDALRDRFQPSR 120 C+PDSP+LVQ+LLACLARG++AFLANPELHRDD A R+T+ ALV+TS L DRF PS Sbjct 61 CMPDSPELVQVLLACLARGILAFLANPELHRDDQAFQERDTQAALVITSGPLCDRFAPST 120 Query 121 VAEAAELMSEAARVAPGGYEPMGGDALAYATYTSGTTGPPKAAIHRHADPLTFVDAMCRK 180 V +AA+L SEAAR P YE +GGDA AYATYTSGTTGPPKAAIHRH D FV+AMC Sbjct 121 VVDAADLFSEAARAGPADYEILGGDAAAYATYTSGTTGPPKAAIHRHCDVFAFVEAMCCN 180 Query 181 ALRLTPEDTGLCSARMYFAYGLGNSVWFPLATGGSAVINSAPVTPEAAAILSARFGPSVL 240 ALRLTP D GL SARMYFAYGLGNSVWFPLATG SAV+N PV E AA LSARF PSVL Sbjct 181 ALRLTPADIGLSSARMYFAYGLGNSVWFPLATGSSAVVNPLPVGAEVAATLSARFEPSVL 240 Query 241 YGVPNFFARVIDSCSPDSFRSLRCVVSAGEALELGLAERLMEFFGGIPILDGIGSTEVGQ 300 YGVPNFFARV+D+CS DSFRS+RCVVSAGEALE+GLAERL EFFGGIPILDG+GSTEVGQ Sbjct 241 YGVPNFFARVVDACSADSFRSVRCVVSAGEALEVGLAERLTEFFGGIPILDGVGSTEVGQ 300 Query 301 TFVSNRVDEWRLGTLGRVLPPYEIRVVAPDGTTAGPGVEGDLWVRGPAIAKGYWNRPDSP 360 TFVSN VDEWR G+LG+VLPPY+IRVVAPDG AGPG EGDLWVRGP+IA+ YWN P+ Sbjct 301 TFVSNTVDEWRPGSLGKVLPPYQIRVVAPDGAAAGPGGEGDLWVRGPSIAESYWNWPEPL 360 Query 361 VANEGWLDTRDRVCIDSDGWVTYRCRADDTEVIGGVNVDPREVERLIIEDEAVAEAAVVA 420 + +EGWLDTRDRVCID DGWVTY CRADDTE++G VN++PRE+ERLI+E++AVAE AVV Sbjct 361 LTDEGWLDTRDRVCIDDDGWVTYACRADDTEIVGAVNINPREIERLIVEEDAVAEVAVVG 420 Query 421 VRESTGASTLQAFLVATSGATIDGSVMRDLHRGLLNRLSAFKVPHRFAVVDRLPRTPNGK 480 V+E+TGASTLQAFLV S IDGSVMR +HR LL RLSAFKVPHRFAVV+RLPRT NGK Sbjct 421 VKEATGASTLQAFLVPASAEGIDGSVMRHIHRRLLTRLSAFKVPHRFAVVERLPRTANGK 480 Query 481 LVRGALRKQSPTKPIWELSLTEPGSGVRAQRDDLSASNMTIAGGNDGGATLRERLVALRQ 540 L+R ALR Q+P KPIWEL+ E S Q DD SAS + ++G + +L+ERL AL+Q Sbjct 481 LLRSALRGQTPAKPIWELASAEHRSDAPGQLDDQSASAL-VSGSRE--VSLKERLAALQQ 537 Query 541 ERQRLVVDAVCAEAAKMLGEPDPWSVDQDLAFSELGFDSQMTVTLCKRLAAVTGLRLPET 600 ER RLV+DAVC E AKMLGEPDP SV++DLAFSELGFDSQMTV LC RLAA TGLR+PET Sbjct 538 ERHRLVLDAVCGETAKMLGEPDPRSVNRDLAFSELGFDSQMTVELCHRLAAATGLRVPET 597 Query 601 VGWDYGSISGLAQYLEAELAGGHGRLKSAGPVNSGATGLWAIEEQLNKVEELVAVIADGE 660 VGWDYGSISGLAQYLEAEL+G R+ SGA L IE QLNKVEEL A IADGE Sbjct 598 VGWDYGSISGLAQYLEAELSGADRRVTPQS-ARSGARALPLIEAQLNKVEELTAAIADGE 656 Query 661 KQRVADRLRALLGTIAGSEAGLGKLIQAASTPDEIFQLIDSELGK 705 K RVA+RLRALLGTI + G+ I AASTPDEIFQLIDSE G+ Sbjct 657 KPRVAERLRALLGTITEGQEHWGQRIAAASTPDEIFQLIDSEFGE 701 >gi|183980136|ref|YP_001848427.1| polyketide synthase PKS [Mycobacterium marinum M] gi|183173462|gb|ACC38572.1| polyketide synthase PKS [Mycobacterium marinum M] Length=2444 Score = 849 bits (2194), Expect = 0.0, Method: Compositional matrix adjust. Identities = 420/637 (66%), Positives = 496/637 (78%), Gaps = 2/637 (0%) Query 1 MRNGNLAGLLAEQASEAGWYDRPAFYAADVVTHGQIHDGAARLGEVLRNRGLSSGDRVLL 60 MRN NLA LLA QA + W PA+YA ++VTH QIH+GAARLG V +RGL +GDRVLL Sbjct 1 MRNNNLAWLLANQALASEWSASPAYYAPNIVTHAQIHEGAARLGNVFGSRGLRTGDRVLL 60 Query 61 CLPDSPDLVQLLLACLARGVMAFLANPELHRDDHALAARNTEPALVVTSDALRDRFQPSR 120 CLPDS DLVQLLLACLARG++AF++NPEL DDH ++T+PALVVT+DALRDRF S Sbjct 61 CLPDSTDLVQLLLACLARGIVAFISNPELRPDDHTFQEQDTQPALVVTTDALRDRFARSG 120 Query 121 VAEAAELMSEAARVAPGGYEPMGGDALAYATYTSGTTGPPKAAIHRHADPLTFVDAMCRK 180 + + EL +EA + P YEP+ GDALAY TYTSGTTG PKAA+HRH D F+DAMCR Sbjct 121 IVDPGELWAEANQAKPAAYEPLTGDALAYGTYTSGTTGAPKAALHRHGDVWAFIDAMCRN 180 Query 181 ALRLTPEDTGLCSARMYFAYGLGNSVWFPLATGGSAVINSAPVTPEAAAILSARFGPSVL 240 ALRLTP+D GL ARMYFAYGLGNSVWFPLATG SAVI+ +P+ E+AA LS RF PSVL Sbjct 181 ALRLTPDDVGLSIARMYFAYGLGNSVWFPLATGSSAVISRSPLGAESAANLSERFSPSVL 240 Query 241 YGVPNFFARVIDSCSPDSFRSLRCVVSAGEALELGLAERLMEFFGGIPILDGIGSTEVGQ 300 YGVP F ARV D+C+ D+FRSLRCVVSAGEALELGLA+RLM+FFGGIP+LDGIGSTEVGQ Sbjct 241 YGVPTFLARVADTCAADAFRSLRCVVSAGEALELGLAQRLMKFFGGIPLLDGIGSTEVGQ 300 Query 301 TFVSNRVDEWRLGTLGRVLPPYEIRVVAPDGTTAGPGVEGDLWVRGPAIAKGYWNRPDSP 360 TF+S+ VDEWRLGTLG+VL PYEIRVVAPDGTTA PGVEGDLWVRGP++ GYWNRP P Sbjct 301 TFISSTVDEWRLGTLGKVLSPYEIRVVAPDGTTAAPGVEGDLWVRGPSLTAGYWNRPTQP 360 Query 361 VA-NEGWLDTRDRVCIDSDGWVTYRCRADDTEVIGGVNVDPREVERLIIEDEAVAEAAVV 419 + ++ WLDTRDRVC+D+ GWVTYRCRADD E++GG+N++PRE+E+LI+ED VAE AVV Sbjct 361 PSISDSWLDTRDRVCVDAHGWVTYRCRADDIEIVGGININPREIEQLIVEDHLVAETAVV 420 Query 420 AVRESTGASTLQAFLVATSGATIDGSVMRDLHRGLLNRLSAFKVPHRFAVVDRLPRTPNG 479 AVRE+TG S LQAFLV SGA++ S +++LHR LL LS KVPHRF + +RLPRT +G Sbjct 421 AVREATGESALQAFLVPESGASLGESAIKELHRRLLGSLSPHKVPHRFEIAERLPRTASG 480 Query 480 KLVRGALRKQSPTKPIWELSLTEPGSGVRAQRDDLSASNMTIAGGNDGGATLRERLVALR 539 KL RG LR Q +P+WE T S QRD + +N + G G TL ERL L+ Sbjct 481 KLQRGQLRTQPAAQPVWERRCTVGTSDSDGQRDPQTQTNYKV-GPRVGPVTLDERLAVLQ 539 Query 540 QERQRLVVDAVCAEAAKMLGEPDPWSVDQDLAFSELGFDSQMTVTLCKRLAAVTGLRLPE 599 QE RL+ D V AE A++LG+P +D+D+AF+ELGFDS+MTV L RLAAVTGLRLPE Sbjct 540 QEGHRLIADTVSAEVAQILGDPAAERIDRDVAFAELGFDSRMTVELRNRLAAVTGLRLPE 599 Query 600 TVGWDYGSISGLAQYLEAELAGGHGRLKSAGPVNSGA 636 TVGWDYGSIS LA +LE ELAG GR K V GA Sbjct 600 TVGWDYGSISRLAAHLETELAGSGGRGKPGPSVAGGA 636 Score = 95.9 bits (237), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 67/175 (39%), Positives = 99/175 (57%), Gaps = 16/175 (9%) Query 531 LRERLVALRQERQ-RLVVDAVCAEAAKMLGEPDPWSVDQDLAFSELGFDSQMTVTLCKRL 589 L +RL AL +Q +L+V+ V +AA +LG P +D + F +LG DS V L RL Sbjct 2277 LAQRLQALSPHQQHQLLVETVRNQAAVVLGRPSGQDIDPECTFQDLGLDSLTAVELRNRL 2336 Query 590 AAVTGLRLPETVGWDYGSISGLAQYLEAELAGGHGRLKSAGPVNSGATGLWAIEEQLNKV 649 A +GL L T+ +DY + + LA++L +L G +G TG IE QL + Sbjct 2337 KAASGLSLSPTLIFDYPTPATLARHLAQQLIG------------TGTTGSAQIESQLETL 2384 Query 650 EELVAVIADGEKQRVADRLRALLG-TIAGSEAG--LGKLIQAASTPDEIFQLIDS 701 ++ + I DG+KQRVA +LR L +A +E+G L I+ A++P EI QLID+ Sbjct 2385 QQTLLAIEDGDKQRVAAQLRKFLTRLLAPAESGRPLDDRIKDATSPSEILQLIDA 2439 >gi|297560725|ref|YP_003679699.1| AMP-dependent synthetase and ligase [Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111] gi|296845173|gb|ADH67193.1| AMP-dependent synthetase and ligase [Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111] Length=514 Score = 335 bits (859), Expect = 2e-89, Method: Compositional matrix adjust. Identities = 203/487 (42%), Positives = 268/487 (56%), Gaps = 5/487 (1%) Query 5 NLAGLLAEQASEAGWYDRPAFYAADVV-THGQIHDGAARLGEVLRNRGLSSGDRVLLCLP 63 NLA L+ E GW DRPA V THGQ+H AAR VL RG+ GD VLL LP Sbjct 2 NLAHDLSRLCGERGWRDRPACLEDGAVWTHGQVHATAARCAAVLAGRGVGPGDHVLLALP 61 Query 64 DSPDLVQLLLACLARGVMAFLANPELHRDDHALAARNTEPALVVTSDALRDRFQPSRVAE 123 D V LAC G +A NP+L +H A + P LV+ + L +RF + Sbjct 62 DGAAWVVSFLACARIGAVAVTVNPDLSGREHRYMASDCAPVLVLAEEHLHERFPDAPALT 121 Query 124 AAELMSEAARVAPGGYEPMGGDALAYATYTSGTTGPPKAAIHRHADPLTFVDAMCRKALR 183 A L++E A AP P G DA Y YTSGTTG PK +HR ADP ++++ + R Sbjct 122 GAALLAEGATRAPAPPVPTGPDAPLYVQYTSGTTGQPKGVVHRCADPASYMELVGRPVAD 181 Query 184 LTPEDTGLCSARMYFAYGLGNSVWFPLATGGSAVINSAPVTPEAAAILSARFGPSVLYGV 243 + P D L ++M+FAYG GN+ FPL +G +AV + A L AR G ++LYGV Sbjct 182 VGPTDVTLSVSKMFFAYGFGNAFVFPLLSGSAAVYTAGRPGAAEVAGLVARHGVTLLYGV 241 Query 244 PNFFARVIDSCSPDSFRSLRCVVSAGEALELGLAERLMEFFGGIPILDGIGSTEVGQTFV 303 P+F+A ++ SP SLR VSAGE L L ER G+P+L+ +GSTE G F Sbjct 242 PSFYANLVREASPADLASLRLAVSAGERLAPDLGERARGLL-GVPLLEQLGSTEAGHGFC 300 Query 304 SNRVDEWRLGTLGRVLPPYEIRVVAPDGTTAGPGVEGDLWVRGPAIAKGYWNRPDS---P 360 SN V GT+GRVLP + +RV+ DG PG G+L V GP + +GY N P+ Sbjct 301 SNTVSRDVPGTVGRVLPGFRVRVLDRDGAPVAPGGTGELHVTGPTLMQGYLNLPEDTRRT 360 Query 361 VANEGWLDTRDRVCIDSDGWVTYRCRADDTEVIGGVNVDPREVERLIIEDEAVAEAAVVA 420 + +GWL T D V G + +R R DD E++GG+ P EVE L+ D V EAAV + Sbjct 361 LPEDGWLRTGDLVTALPSGDLVHRGRTDDLEMVGGITFSPVEVEDLLRSDPRVREAAVTS 420 Query 421 VRESTGASTLQAFLVATSGATIDGSVMRDLHRGLLNRLSAFKVPHRFAVVDRLPRTPNGK 480 + + GA+ L AF+V S A ++ +L GL R++ +KVP +V LPRTP GK Sbjct 421 LPDERGATRLHAFVVPASSADSAETLESELIDGLRGRVAPYKVPRSVRLVPDLPRTPTGK 480 Query 481 LVRGALR 487 L R LR Sbjct 481 LRRFQLR 487 >gi|297155049|gb|ADI04761.1| AMP-binding protein [Streptomyces bingchenggensis BCW-1] Length=1063 Score = 317 bits (813), Expect = 3e-84, Method: Compositional matrix adjust. Identities = 200/496 (41%), Positives = 273/496 (56%), Gaps = 13/496 (2%) Query 5 NLAGLLAEQASEAGWYDRPAFYAADVV-THGQIHDGAARLGEVLRNRGLSSGDRVLLCLP 63 NLA LA +A +AGW RPAF V THG+IHD AAR+ VL RG+++GDR+L+ LP Sbjct 9 NLAEHLAVRAEQAGWSARPAFVEGHRVWTHGEIHDLAARMATVLARRGVTAGDRILIALP 68 Query 64 DSPDLVQLLLACLARGVMAFLANPELHRDDHALAARNTEPALVVTSDALRDRFQPSRVAE 123 D V LA G +A L NP L D+H A N++ L V+ + D F+ R Sbjct 69 DGVPWVSAFLATARLGGIAVLVNPALTADEHRFMAENSKAVLCVSGPGIEDHFEADRWLG 128 Query 124 AAELMSEAARVAPG-GYEPMGGDALAYATYTSGTTGPPKAAIHRHADPLTFVDAMCRKAL 182 A +L + A +P EP+ A Y YTSGTTG PK +H H DP + + + + L Sbjct 129 ADQLSALACTASPATAAEPVTARAPLYIQYTSGTTGRPKGVVHCHGDPAAYWELVGKDVL 188 Query 183 RLTPEDTGLCSARMYFAYGLGNSVWFPLATGGSAVINSAPVTPEAAAILSARFGPSVLYG 242 + P+D +R+++AYG GN+ FPL +G SAV+ S+ P + AR SVLY Sbjct 189 DIGPDDVAFSVSRLFYAYGFGNAFVFPLFSGSSAVLTSSRPGPSLTDDVIARHRVSVLYS 248 Query 243 VPNFFARVID---SCSPDSFRSLRCVVSAGEALELGLAERLMEFFGGIPILDGIGSTEVG 299 VP+ +A ++D + F S+R VSAGE L L ER+ E G P+L+ IGSTE G Sbjct 249 VPSAYAALVDERGAGHAACFSSVRAAVSAGEGLPGTLGERVGELLGA-PVLEQIGSTEAG 307 Query 300 QTFVSNRVDEWRLGTLGRVLPPYEIRVVAPDGTTAGPGVEGDLWVRGPAIAKGYWNRPDS 359 F +N V GT+G +P +E+ + G G EG+LWVRGP + GY P+ Sbjct 308 HAFCANSVWANSPGTVGLPVPRFELELRDGTGAVVPDGAEGELWVRGPTVTPGYLGLPEE 367 Query 360 PVAN--EGWLDTRDRVCIDSDGWVTYRCRADDTEVIGGVNVDPREVERLIIEDEAVAEAA 417 A GWL TRDR + DG + R DD E++GG+ V P EVE ++ +V E A Sbjct 368 SRARLVGGWLGTRDRARREPDGSYRHLGRVDDLEMVGGITVSPLEVENVLRRHPSVREVA 427 Query 418 VVAVRESTGASTLQAFLVATS----GATIDGSVMR-DLHRGLLNRLSAFKVPHRFAVVDR 472 V AV + GA+ L AF+V + G+ IDG + DL RL+AFK P +V Sbjct 428 VAAVPDDRGATRLHAFVVPAAPTGEGSGIDGRALSADLIALARRRLAAFKAPRAVHLVPS 487 Query 473 LPRTPNGKLVRGALRK 488 LPRTP+GKL R +R+ Sbjct 488 LPRTPSGKLRRHLVRQ 503 >gi|29827718|ref|NP_822352.1| acyl-CoA synthase [Streptomyces avermitilis MA-4680] gi|29604818|dbj|BAC68887.1| putative acyl-CoA synthetase [Streptomyces avermitilis MA-4680] Length=508 Score = 314 bits (804), Expect = 4e-83, Method: Compositional matrix adjust. Identities = 201/491 (41%), Positives = 268/491 (55%), Gaps = 10/491 (2%) Query 5 NLAGLLAEQASEAGWYDRPAFYAADVV-THGQIHDGAARLGEVLRNRGLSSGDRVLLCLP 63 NLA +LA +A GW RPAF V THG++HD AAR VL G+ GDRVLL LP Sbjct 18 NLAAVLAGRAERRGWTGRPAFRQGHQVWTHGEVHDLAARTATVLAEHGVRPGDRVLLALP 77 Query 64 DSPDLVQLLLACLARGVMAFLANPELHRDDHALAARNTEPALVVTSDALRDRFQPSRVAE 123 DS V LA G +A NPEL +H A + E AL VT L RF R Sbjct 78 DSLAWVTAFLATARLGAVAVPVNPELTPAEHEFMADDAEAALCVTGPGLERRFAHRRRLG 137 Query 124 AAELMSEAARVAPGG-YEPMGGDALAYATYTSGTTGPPKAAIHRHADPLTFVDAMCRKAL 182 A +L++ A +P P+G Y YTSGTTG PK +H H DP T+ + + R+ L Sbjct 138 ADQLVALAGTASPAADAHPVGPRTPLYIQYTSGTTGRPKGVVHCHGDPGTYHELIGRRLL 197 Query 183 RLTPEDTGLCSARMYFAYGLGNSVWFPLATGGSAVINSAPVTPEAAAILSARFGPSVLYG 242 R+T +D L ++++FAYG GN+ FPL +G SAV+ TP A L AR ++LY Sbjct 198 RITADDVTLSVSKLFFAYGFGNAFVFPLFSGSSAVLVDGRPTPAAVDGLVARHRVTLLYS 257 Query 243 VPNFFARVIDSCSPDS---FRSLRCVVSAGEALELGLAERLMEFFGGIPILDGIGSTEVG 299 VP+ +A ++ + F S+R VSAGE + GLAE++ E G P+L+ +GSTE G Sbjct 258 VPSAYAALVADRAVGHMACFASVRAAVSAGEGMPAGLAEQVAELLGA-PVLEQLGSTEAG 316 Query 300 QTFVSNRVDEWRLGTLGRVLPPYEIRVVAPDGTTAGPGVEGDLWVRGPAIAKGYWNRPDS 359 F +N D GT+GR +P +E+ + G G G EG+LWVRGP++ GY N P+ Sbjct 317 HAFCANSFDHHHPGTVGRPVPGFEVELRDRSGRPVGAGEEGELWVRGPSLTPGYLNLPEE 376 Query 360 P--VANEGWLDTRDRVCIDSDGWVTYRCRADDTEVIGGVNVDPREVERLIIEDEAVAEAA 417 GWL TRDR + DG + R DD E +GG V P EVE L+ AV E A Sbjct 377 TDRTLVGGWLATRDRARREPDGTYRHLGRTDDMETVGGSTVSPLEVEALLGTHPAVREIA 436 Query 418 VVAVRESTGASTLQAFLVATSGATIDGSVMRDLHRGLLNRLSAFKVPHRFAVVDRLPRTP 477 V AV ++ GA L+AF+V + I + DL + L+A +VP + V LPRT Sbjct 437 VAAVTDARGAGRLRAFVVPVT--PIPVGLEADLVCLARDNLAAVQVPRSVSFVPTLPRTA 494 Query 478 NGKLVRGALRK 488 GKL R +R+ Sbjct 495 TGKLRRHLVRQ 505 >gi|290955412|ref|YP_003486594.1| AMP-binding protein [Streptomyces scabiei 87.22] gi|260644938|emb|CBG68024.1| putative AMP-binding enzyme [Streptomyces scabiei 87.22] Length=538 Score = 313 bits (802), Expect = 6e-83, Method: Compositional matrix adjust. Identities = 208/522 (40%), Positives = 278/522 (54%), Gaps = 43/522 (8%) Query 4 GNLAGLLAEQASEAGWYDRPAFYAAD-VVTHGQIHDGAARLGEVLRNRGLSSGDRVLLCL 62 GNLA LA A GW RPAF+ +HG++HD AAR VL + G+ GDRVLL L Sbjct 20 GNLAAHLAALAERRGWTGRPAFHQGHRAYSHGEVHDLAARTATVLADHGVRPGDRVLLAL 79 Query 63 PDSPDLVQLLLACLARGVMAFLANPELHRDDHALAARNTEPALVVTSDAL---------- 112 PDS V LA G +A L NPEL + A +TE L VT AL Sbjct 80 PDSVTWVTTFLALARLGAVAVLVNPELTPPELQFMAEDTEAVLWVTGPALDSYIPAPRTP 139 Query 113 ---------RDRFQPSRVAEAA--------ELMSEAARVAPGGY-EPMGGDALAYATYTS 154 +R +P+R A +L + +A P Y P+ Y YTS Sbjct 140 RAAAAPPQAHERHRPARGGATASPPRLGSDQLTALSATALPTPYAHPVDAHTPLYIQYTS 199 Query 155 GTTGPPKAAIHRHADPLTFVDAMCRKALRLTPEDTGLCSARMYFAYGLGNSVWFPLATGG 214 GTTG PK +H H DP T+ D + R+ LR+TP+D L +R+YFAYG GN++ FPL +G Sbjct 200 GTTGRPKGVVHVHGDPRTYHDLIGRRLLRVTPDDVTLSVSRLYFAYGFGNALVFPLFSGS 259 Query 215 SAVINSAPVTPEAAAILSARFGPSVLYGVPNFFARVIDSCS---PDSFRSLRCVVSAGEA 271 SAV+ TP A L AR ++LY VP+ +A ++ + + F S+R VSAGE Sbjct 260 SAVLADRRPTPAAVDELVARHRVTLLYSVPSAYAALVADRADGHEECFASVRAAVSAGEG 319 Query 272 LELGLAERLMEFFGGIPILDGIGSTEVGQTFVSNRVDEWRLGTLGRVLPPYEIRVVAPDG 331 + GL +++ E G P+L+ IGSTE G F +N D GT+GR +P +E+ + G Sbjct 320 MPAGLGKQVTELLGA-PVLEQIGSTEAGHAFCANSFDHNHPGTVGRPVPGFEVELRDRAG 378 Query 332 TTAGPGVEGDLWVRGPAIAKGYWNRPDSPVANE-----GWLDTRDRVCIDSDGWVTYRCR 386 G G+LWVRGP + GY NRP+ NE GWL+TRDR + DG + R Sbjct 379 AQVADGEAGELWVRGPTVTPGYLNRPEE---NERTLVGGWLNTRDRAVREPDGTYRHLGR 435 Query 387 ADDTEVIGGVNVDPREVERLIIEDEAVAEAAVVAVRESTGASTLQAFLVATSGATIDGSV 446 ADD E++GG+ V P EVE L+ V + AV AV + GAS L+AF+V I + Sbjct 436 ADDMEMVGGITVSPLEVEALLRTHPGVRDVAVAAVTDERGASRLRAFVVPVP--PIGVGL 493 Query 447 MRDLHRGLLNRLSAFKVPHRFAVVDRLPRTPNGKLVRGALRK 488 +L R +RL+AFKVP + V LPRT GKL R +R+ Sbjct 494 EAELIRMARDRLAAFKVPRSVSFVPTLPRTATGKLRRHLVRQ 535 >gi|254383649|ref|ZP_04998998.1| acyl-CoA synthase [Streptomyces sp. Mg1] gi|194342543|gb|EDX23509.1| acyl-CoA synthase [Streptomyces sp. Mg1] Length=514 Score = 311 bits (798), Expect = 2e-82, Method: Compositional matrix adjust. Identities = 193/489 (40%), Positives = 261/489 (54%), Gaps = 4/489 (0%) Query 5 NLAGLLAEQASEAGWYDRPAFYAAD-VVTHGQIHDGAARLGEVLRNRGLSSGDRVLLCLP 63 N+A L E+A +GW DR A+Y D VTHG++H AAR VL G+ G VL+ LP Sbjct 26 NMAAALGEEALRSGWTDRIAYYEGDRTVTHGEVHSLAARAASVLAGHGVGQGSSVLITLP 85 Query 64 DSPDLVQLLLACLARGVMAFLANPELHRDDHALAARNTEPALVVTSDALRDRFQPSRVAE 123 D V LA G +A LANP L D HA A+++E LVV+ L +RF Sbjct 86 DGIAWVVAFLASARLGAVAVLANPGLTADRHAYVAKDSEAVLVVSEAGLAERFPGLAHLT 145 Query 124 AAELMSEAARVAPGGYEPMGGDALAYATYTSGTTGPPKAAIHRHADPLTFVDAMCRKALR 183 A+L+ AA P +G D Y YTSGTTG PK +HRH D + ++ + Sbjct 146 GAQLVERAAEEDPAPAARLGPDHPLYIQYTSGTTGLPKGVVHRHEDMEIYYSGAGKQVIG 205 Query 184 LTPEDTGLCSARMYFAYGLGNSVWFPLATGGSAVINSAPVTPEAAAILSARFGPSVLYGV 243 +D L ++++FAYGLGN++ FPL +GG+AV+ P P A L AR + LY V Sbjct 206 FGRDDIALSVSKLFFAYGLGNALAFPLWSGGAAVLEPGPPRPARIAELVARHRVTYLYAV 265 Query 244 PNFFARVIDSCSPDSFRSLRCVVSAGEALELGLAERLMEFFGGIPILDGIGSTEVGQTFV 303 P+ +A ++ P F ++R VSAGE L L ER F G P+ D +GSTE G Sbjct 266 PSAYANILAETDPADFATVRAAVSAGERLTDELRERAAAFLGA-PLYDQLGSTEAGHAIA 324 Query 304 SNRVDEWRLGTLGRVLPPYEIRVVAPDGTTAGPGVEGDLWVRGPAIAKGYWNRPDSPVAN 363 +N GT+GR +P +E V DGT GV G+LWVRGP + +GY P+ Sbjct 325 TNGDFFHEPGTVGRPVPGFEAEVRDRDGTPVPDGVAGELWVRGPTVTRGYLGLPEETART 384 Query 364 --EGWLDTRDRVCIDSDGWVTYRCRADDTEVIGGVNVDPREVERLIIEDEAVAEAAVVAV 421 EGWL+TRDRV DG +T+ R DD E++GG+ P E+E+++ AV + AV V Sbjct 385 LVEGWLNTRDRVVRGEDGTLTHSGRTDDLEMVGGITFSPLEIEQVLARHPAVRDIAVACV 444 Query 422 RESTGASTLQAFLVATSGATIDGSVMRDLHRGLLNRLSAFKVPHRFAVVDRLPRTPNGKL 481 GAS L+AF+V A + +L L +KVP VV+ LPRT GKL Sbjct 445 PNDRGASKLRAFVVLRPDAHDTAELEPELVGLARAVLEPYKVPRAVQVVESLPRTATGKL 504 Query 482 VRGALRKQS 490 R +R+ S Sbjct 505 QRFLIRQGS 513 >gi|288917259|ref|ZP_06411627.1| AMP-dependent synthetase and ligase [Frankia sp. EUN1f] gi|288351281|gb|EFC85490.1| AMP-dependent synthetase and ligase [Frankia sp. EUN1f] Length=534 Score = 306 bits (785), Expect = 6e-81, Method: Compositional matrix adjust. Identities = 195/487 (41%), Positives = 264/487 (55%), Gaps = 6/487 (1%) Query 5 NLAGLLAEQASEAGWYDRPAFYAAD-VVTHGQIHDGAARLGEVLRNRGLSSGDRVLLCLP 63 NLA LA+ A GW DRPA D VVT+G++HD AAR+G+VL G G RVL+ L Sbjct 8 NLAAELADLARSRGWTDRPALLFEDQVVTYGELHDLAARVGQVLVRHGAGPGRRVLIALS 67 Query 64 DSPDLVQLLLACLARGVMAFLANPELHRDDHALAARNTEPALVVTSDALRDRFQPSRVAE 123 D P V L + G A NP L DDH A + +VV + + RF + V Sbjct 68 DGPAWVAAFLGTVRCGATAVPVNPLLTADDHGFMADDCAARIVVADEEICSRFTATVVRS 127 Query 124 AAELMSEAARVAPGGYEPMGGDALAYATYTSGTTGPPKAAIHRHADPLTFVDAMCRKALR 183 +L++EA + G + D Y TYTSGTTG PK A+ R +P + + + LR Sbjct 128 GDQLLAEAHQAEAGPV--VHTDDPLYLTYTSGTTGSPKGAMFRQGNPRFYHQNIGQALLR 185 Query 184 LTPEDTGLCSARMYFAYGLGNSVWFPLATGGSAVINSAPVTPEAAAILSARFGPSVLYGV 243 P D L +++YF YGL NS+ FPL +GGS V+ PEA L +R G ++LY V Sbjct 186 SGPTDVTLSVSKLYFGYGLCNSLVFPLYSGGSVVLLRERPGPEAVEGLVSRHGVTLLYAV 245 Query 244 PNFFARVIDSCSPDSFRSLRCVVSAGEALELGLAERLMEFFGGIPILDGIGSTEVGQTFV 303 P+ FA + S P SF S+R VSAGE L L L R + G P+L+ +G TEVG FV Sbjct 246 PSAFAGLGRSAEPASFGSVRAAVSAGERLSLELGGRTSDLLGA-PVLEQLGQTEVGCAFV 304 Query 304 SNRVDEWRLGTLGRVLPPYEIRVVAPDGTTAGPGVEGDLWVRGPAIAKGYWNRPDSPVA- 362 +N V+ GT+GR +P + ++V P+G G G+LWV GP + GY NRP+ Sbjct 305 ANGVEANVPGTVGRAVPGFTVQVRDPEGRPCPDGTVGELWVTGPTLMIGYLNRPEQTATA 364 Query 363 -NEGWLDTRDRVCIDSDGWVTYRCRADDTEVIGGVNVDPREVERLIIEDEAVAEAAVVAV 421 GWL T DR + DG + R DD E++GG+ V P E+E ++ V+E AV AV Sbjct 365 LRGGWLATNDRGMRNPDGTFVHLGRLDDLEMVGGITVSPLEIEGVLGAHPLVSEVAVAAV 424 Query 422 RESTGASTLQAFLVATSGATIDGSVMRDLHRGLLNRLSAFKVPHRFAVVDRLPRTPNGKL 481 + TGA+ L+A++V + +DL RL+ FKVP +V LPRT +GKL Sbjct 425 PDETGATRLRAYVVPRRPDESGSRLEQDLVGFARERLAPFKVPRTVHLVPALPRTASGKL 484 Query 482 VRGALRK 488 R LR Sbjct 485 RRFQLRS 491 >gi|302553683|ref|ZP_07306025.1| dicarboxylate-CoA ligase PimA [Streptomyces viridochromogenes DSM 40736] gi|302471301|gb|EFL34394.1| dicarboxylate-CoA ligase PimA [Streptomyces viridochromogenes DSM 40736] Length=507 Score = 303 bits (775), Expect = 1e-79, Method: Compositional matrix adjust. Identities = 204/492 (42%), Positives = 266/492 (55%), Gaps = 11/492 (2%) Query 4 GNLAGLLAEQASEAGWYDRPAFYAADVV-THGQIHDGAARLGEVLRNRGLSSGDRVLLCL 62 GNLA LAE A GW R AF+ THG++HD AAR VL G+ GDRVLL L Sbjct 17 GNLAAQLAELAERRGWGGRTAFHQGHRAWTHGEVHDLAARAATVLAGYGVRPGDRVLLAL 76 Query 63 PDSPDLVQLLLACLARGVMAFLANPELHRDDHALAARNTEPALVVTSDALRDRFQPSRVA 122 PDS V LA G +A L NPEL DHA A + L V L +RF Sbjct 77 PDSVAWVTAFLATARLGAVAVLVNPELPAADHAFLAEDIAAVLCVAGPGLEERFAGRAGL 136 Query 123 EAAELMSEAARVAPGGYEPMGGDALAYATYTSGTTGPPKAAIHRHADPLTFVDAMCRKAL 182 A +LM+ A+ P + + Y YTSGTTG PK +H H DP T+ D + R+ L Sbjct 137 GADQLMTLASAAEPAPAHQVEAHSPLYVQYTSGTTGRPKGVVHTHGDPRTYHDLIGRRVL 196 Query 183 RLTPEDTGLCSARMYFAYGLGNSVWFPLATGGSAVINSAPVTPEAAAILSARFGPSVLYG 242 R+T +D L ++++FAYG GN+ FPL +G SAV+ TP A L AR ++LY Sbjct 197 RITADDVTLSVSKLFFAYGFGNAFVFPLFSGSSAVLVDRRPTPTAIDELVARHRVTLLYS 256 Query 243 VPNFFARVI---DSCSPDSFRSLRCVVSAGEALELGLAERLMEFFGGIPILDGIGSTEVG 299 VP+ +A ++ F S+R VSAGE L GLA ++ G P+L+ IGSTE G Sbjct 257 VPSAYAALVAERGHGHEGCFASVRAAVSAGEGLPEGLARQVGALLGA-PVLEQIGSTEAG 315 Query 300 QTFVSNRVDEWRLGTLGRVLPPYEIRVVAPDGTTAGPGVEGDLWVRGPAIAKGYWNRPDS 359 F +N GT+GR +P +E+ + DG G EG++WVRGP + GY +RP+ Sbjct 316 HAFCANGFAHNHPGTVGRPVPGFEVELRDRDGGPVPDGEEGEMWVRGPTVTPGYLDRPEE 375 Query 360 PVAN--EGWLDTRDRVCIDSDGWVTYRCRADDTEVIGGVNVDPREVERLIIEDEAVAEAA 417 GWL TRDR + DG + RADD E++GG+ V P EVE ++ AV E A Sbjct 376 TARTLAGGWLATRDRARREPDGTYRHLGRADDMEMVGGITVSPLEVEAVLHGHPAVREVA 435 Query 418 VVAVRESTGASTLQAFLVATSGATIDGSVMRDLHRGLLNR-LSAFKVPHRFAVVDRLPRT 476 V AV + GAS L+AF+V DG + D GL L+AFKVP + V LPRT Sbjct 436 VAAVPDGRGASRLRAFVVPAP-PVRDG--LADELIGLARESLAAFKVPRSVSFVPSLPRT 492 Query 477 PNGKLVRGALRK 488 P GKL R +R+ Sbjct 493 PTGKLRRHLVRR 504 >gi|337769466|emb|CCB78179.1| Acyl-CoA synthase [Streptomyces cattleya NRRL 8057] Length=490 Score = 295 bits (755), Expect = 2e-77, Method: Compositional matrix adjust. Identities = 192/489 (40%), Positives = 262/489 (54%), Gaps = 4/489 (0%) Query 5 NLAGLLAEQASEAGWYDRPAFYAAD-VVTHGQIHDGAARLGEVLRNRGLSSGDRVLLCLP 63 N+A LA A GW DRPA+Y AD V+THGQ+HD AAR VL + G++ RVL+ LP Sbjct 2 NMAEDLAALALGRGWTDRPAYYEADRVITHGQLHDLAARAATVLADAGVTPARRVLIALP 61 Query 64 DSPDLVQLLLACLARGVMAFLANPELHRDDHALAARNTEPALVVTSDALRDRFQPSRVAE 123 D V LA G A L NP L DHA A ++E L VT L DRF R + Sbjct 62 DGIAWVTAFLATARLGATAVLVNPALTAADHAFLAADSETYLAVTEAPLADRFTGIRHLD 121 Query 124 AAELMSEAARVAPGGYEPMGGDALAYATYTSGTTGPPKAAIHRHADPLTFVDAMCRKALR 183 A L AA P + D Y YTSGTT K +HRHADP + + LR Sbjct 122 GAALPRLAAARPPAPAAEVAPDHPLYIQYTSGTTSRAKGVVHRHADPAAYHAGAGAQVLR 181 Query 184 LTPEDTGLCSARMYFAYGLGNSVWFPLATGGSAVINSAPVTPEAAAILSARFGPSVLYGV 243 + P+D L +++++AYG GN++ FPL +GGSAV+ P P A L AR S LY V Sbjct 182 IGPDDVTLSVSKLFYAYGFGNALAFPLHSGGSAVLVPGPPRPPVVAALVARHRVSHLYAV 241 Query 244 PNFFARVIDSCSPDSFRSLRCVVSAGEALELGLAERLMEFFGGIPILDGIGSTEVGQTFV 303 P+ A ++ P FRS+R V++AGE L LA+R+ EF G P+ D +GSTE G Sbjct 242 PSALANLLAETDPADFRSVRAVITAGEPLGAQLADRVGEFLGA-PLYDQLGSTEAGHAIC 300 Query 304 SNRVDEWRLGTLGRVLPPYEIRVVAPDGTTAGPGVEGDLWVRGPAIAKGYWNRP--DSPV 361 +N GT+GR P + I + G G EG++WV GP + GY RP + + Sbjct 301 TNGPACHVPGTVGRPAPGFRIELRDRAGRPVPDGTEGEMWVHGPTVTPGYLGRPAETARL 360 Query 362 ANEGWLDTRDRVCIDSDGWVTYRCRADDTEVIGGVNVDPREVERLIIEDEAVAEAAVVAV 421 +GWL+TRDR + DG + R DD E++GG+ V P E+E+++ V + AV ++ Sbjct 361 IVDGWLNTRDRAVRNPDGTYRHLGRTDDLEMVGGITVSPLEIEQVLAGHPGVRDVAVASI 420 Query 422 RESTGASTLQAFLVATSGATIDGSVMRDLHRGLLNRLSAFKVPHRFAVVDRLPRTPNGKL 481 GA+ L+AF+V + + +L RL+ +KVP +V LPRT GKL Sbjct 421 GNERGATKLRAFVVPRRPVSDPEAFATELTGLARRRLAPYKVPRGVELVPSLPRTATGKL 480 Query 482 VRGALRKQS 490 R +R+ S Sbjct 481 QRFLVRQGS 489 >gi|134100572|ref|YP_001106233.1| acyl-CoA synthase [Saccharopolyspora erythraea NRRL 2338] gi|291006421|ref|ZP_06564394.1| acyl-CoA synthase [Saccharopolyspora erythraea NRRL 2338] gi|133913195|emb|CAM03308.1| acyl-CoA synthase [Saccharopolyspora erythraea NRRL 2338] Length=497 Score = 281 bits (719), Expect = 3e-73, Method: Compositional matrix adjust. Identities = 183/494 (38%), Positives = 251/494 (51%), Gaps = 8/494 (1%) Query 5 NLAGLLAEQASEAGWYDRPAFYA-ADVVTHGQIHDGAARLGEVLRNRGLSSGDRVLLCLP 63 N AG LA A+ GW RPAF+ HGQ+HD AAR VL RG + RVL+ L Sbjct 2 NFAGDLAALATSRGWNSRPAFHTPGGSYAHGQVHDLAARAAGVLLRRGATPRSRVLVVLS 61 Query 64 DSPDLVQLLLACLARGVMAFLANPELHRDDHALAARNTEPALVVTSDALRDRFQPSRVAE 123 D V LA G + NP L +DH L A + + ALVVT+ L RF V + Sbjct 62 DDIGWVVTFLAAARIGATPVITNPALTPEDHVLIAGDCDAALVVTTGELAGRFAAGNVVD 121 Query 124 AAELMSEAARVAPGGYEPMGGDALAYATYTSGTTGPPKAAIHRHADPLTFVDAMCRKALR 183 EL+SEA P P+ DA Y YTSGTTG PK +R P + + +A R Sbjct 122 VGELLSEAVAAEP--MPPVTTDAPLYVYYTSGTTGAPKGVAYRQGSPAVYHRHIGVEAFR 179 Query 184 LTPEDTGLCSARMYFAYGLGNSVWFPLATGGSAVINSAPVTPEAAAILSARFGPSVLYGV 243 + P+D L +++YF YG N+ FPL +G SAV+ TP L R G ++LY V Sbjct 180 IGPDDVTLSVSKLYFGYGFCNTFVFPLHSGSSAVLVGDRPTPAMTEELVRRHGVTMLYSV 239 Query 244 PNFFARVIDSCSPDSFRSLRCVVSAGEALELGLAERLMEFFGGIPILDGIGSTEVGQTFV 303 P+ + R++ +F ++R VS GE A + EF P+ + +G TEVG Sbjct 240 PSGYGRLVAEADGRAFTTVRMAVSGGEQFPAEKASQTAEFLSA-PLFNQLGLTEVGCAAT 298 Query 304 SNRVDEWRLGTLGRVLPPYEIRVVAPDGTTAGPGVEGDLWVRGPAIAKGYWNRPD--SPV 361 +N RLGT+GR + +E++V DG G +G+LW+R P Y N+P+ Sbjct 299 ANGFGFNRLGTVGRPVSAFELQVRDADGAVLGDQQQGELWIR-PVRMTEYLNQPELTGRT 357 Query 362 ANEGWLDTRDRVCIDSDGWVTYRCRADDTEVIGGVNVDPREVERLIIEDEAVAEAAVVAV 421 +GW + DRV + DG + R DD E++GG+ V P EVE ++ V E V AV Sbjct 358 LVDGWFRSGDRVSREPDGSYLHHGRMDDLEMVGGIKVSPLEVEAVLGAHPGVEEIGVAAV 417 Query 422 RESTGASTLQAFLVATSGATIDGSVMRDLHRGLLNRLSAFKVPHRFAVVDRLPRTPNGKL 481 + GA+ L+AF+V A + R+L RL+ FKVP V+ LPRT +GKL Sbjct 418 PDEVGATKLRAFVVPADPAQDPAVLERELIELARRRLAPFKVPRSVRTVESLPRTHSGKL 477 Query 482 VRGALRKQSPTKPI 495 R LR T P+ Sbjct 478 RRFELRGHG-TAPL 490 >gi|254386312|ref|ZP_05001620.1| hypothetical protein SSAG_05942 [Streptomyces sp. Mg1] gi|194345165|gb|EDX26131.1| hypothetical protein SSAG_05942 [Streptomyces sp. Mg1] Length=526 Score = 275 bits (704), Expect = 2e-71, Method: Compositional matrix adjust. Identities = 196/496 (40%), Positives = 262/496 (53%), Gaps = 26/496 (5%) Query 5 NLAGLLAEQASEAGWYDRPAFYA-ADVVTHGQIHDGAARLGEVLRNRGLSSGDRVLLCLP 63 NL L + A++ GW +RPA++ DV + ++ GAAR +RGL G R+LL LP Sbjct 35 NLVRRLVDTAADRGWMERPAYFVDEDVHRYEDVYAGAARAAAAYASRGLGPGARILLALP 94 Query 64 DSPDLVQLLLACLARGVMAFLANPELHRDDHALAARNTEPALVVTSDALRDRFQPSRVAE 123 D + V+ L L G +A N LH D+ AA PA+VV+ +RF Sbjct 95 DGIEFVRAFLGALHIGAVAVPVNSMLHPDEMRRAADIARPAVVVSVPEFAERF------- 147 Query 124 AAELMSEAARVAPG---GYEPMGGDALAYATYTSGTTGPPKAAIHRHADPLTFVDAMCRK 180 A +++ G Y P D A+A +TSGTTG PK H H DP A Sbjct 148 AVPVLTPDVLDCDGPVPAYAPCTTDTPAFAAFTSGTTGGPKLCFHTHGDPEILSRA-AGA 206 Query 181 ALRLTPEDTGLCSARMYFAYGLGNSVWFPLATGGSAVINSAPVTPEAAAILSARFGPSVL 240 A+ + P+D RM FAYGLGNS++F L +GGS V+ + P + + R+G SV Sbjct 207 AVGVGPDDVSYSVPRMNFAYGLGNSLFFSLLSGGSTVLTPRRLAPGDSLAVLERYGVSVF 266 Query 241 YGVPNFFARVIDSCSPDSFR---SLRCVVSAGEALELGLAERLMEFFGGIPILDGIGSTE 297 Y P FFA ++ PD+ R LR V AGE L L ER + G +L+ G+TE Sbjct 267 YSQPTFFAHMLGH--PDAARILGGLRVAVVAGEVLPESL-ERTLRGILGPRLLNVYGTTE 323 Query 298 VGQTFVSNRVDEWRLGTLGRVLPPYEIRVVAPDGTTAGPGVEGDLWVRGPAIAKGYWNRP 357 +G ++N E R TLGRVLPPY +RVV DG A PGVEG L V GP I G + Sbjct 324 IGHALLANGPGEMREFTLGRVLPPYRLRVVGDDGEAAAPGVEGRLEVSGPTIGLGVPHGD 383 Query 358 DSPV--ANEGWLDTRDRVCIDSDGWVTYRCRADDTEVIGGVNVDPREVERLIIEDEAVAE 415 +PV A + W T D +D+DG+V R DD E++GGVNV P E+E ++ AV E Sbjct 384 AAPVRLAADQWYSTSDAATMDADGFVRVHGRLDDVEIVGGVNVHPTEIEDRLMAHPAVEE 443 Query 416 AAVVAVRESTGASTLQAFLVATSGATIDGSVMRDLHRGLL----NRLSAFKVPHRFAVVD 471 AAV AVR+ TG S L+A+ V +D + L LL + L+ +KVPH V Sbjct 444 AAVCAVRQDTGISVLRAYAVLRD--PLDSAAAEALRGELLLAAADSLTWYKVPHDITFVA 501 Query 472 RLPRTPNGKLVRGALR 487 RLPR P GKL+R +R Sbjct 502 RLPRNPTGKLLRRTIR 517 >gi|271965232|ref|YP_003339428.1| benzoate-coenzyme A ligase [Streptosporangium roseum DSM 43021] gi|270508407|gb|ACZ86685.1| benzoate-coenzyme A ligase [Streptosporangium roseum DSM 43021] Length=522 Score = 275 bits (703), Expect = 2e-71, Method: Compositional matrix adjust. Identities = 195/487 (41%), Positives = 252/487 (52%), Gaps = 5/487 (1%) Query 5 NLAGLLAEQASEAGWYDRPAFYAADVV-THGQIHDGAARLGEVLRNRGLSSGDRVLLCLP 63 N+A LAE A GW PAF++ D V +HG++HD AAR L G+ GDRV+L Sbjct 35 NIAAELAELAQRNGWAASPAFHSGDRVWSHGEVHDLAARTTSALVGLGVRPGDRVMLAHG 94 Query 64 DSPDLVQLLLACLARGVMAFLANPELHRDDHALAARNTEPALVVTSDALRDRFQPSRVAE 123 D V L G NPEL DHA A + E +LVV D DRF Sbjct 95 DGVAWVAAFLGTARLGATVVPVNPELTAADHAFMAEDCEASLVVAEDRTADRFDGLPCLT 154 Query 124 AAELMSEAARVAPGGYEPMGGDALAYATYTSGTTGPPKAAIHRHADPLTFVDAMCRKALR 183 L+ AA APG + G YA YTSGTTG PKAA+HRHAD + A + + Sbjct 155 GDRLLDLAAGAAPGPVARVTGATALYAQYTSGTTGAPKAALHRHADLALYHRAAGQGVVG 214 Query 184 LTPEDTGLCSARMYFAYGLGNSVWFPLATGGSAVINSAPVTPEAAAILSARFGPSVLYGV 243 + +D L ++++FAYGLGN++ FPL +G SAV+ P R G +VLY V Sbjct 215 IRHDDVTLSVSKLFFAYGLGNALVFPLFSGSSAVLLGDRPGPAQIEETVERHGVTVLYAV 274 Query 244 PNFFARVIDSCSPDSFRSLRCVVSAGEALELGLAERLMEFFGGIPILDGIGSTEVGQTFV 303 P+ +A V C SF S+R VSAGE+L P+LD +GSTE G F Sbjct 275 PSAYANVAAECDGASFASVRVAVSAGESLN-ETLAARARDLLAAPVLDQLGSTEAGHAFC 333 Query 304 SNRVDEWRLGTLGRVLPPYEIRVVAPDGTTAGPGVEGDLWVRGPAIAKGYWNRPDSPVAN 363 S+ +D GT+GR L YEI++ DG G EG+LWVRG ++ GY NRP+ Sbjct 334 SSTLDADEAGTIGRPLAGYEIQIRDDDGGPVSEG-EGELWVRGGSVMAGYLNRPEQTART 392 Query 364 --EGWLDTRDRVCIDSDGWVTYRCRADDTEVIGGVNVDPREVERLIIEDEAVAEAAVVAV 421 +GWL T DR G +R R DD E++GG+ + P EVER++ E AVAE V V Sbjct 393 LVDGWLRTGDRAERLPGGAYVHRGRRDDLEMVGGITMSPVEVERVLAEHPAVAEVVVAVV 452 Query 422 RESTGASTLQAFLVATSGATIDGSVMRDLHRGLLNRLSAFKVPHRFAVVDRLPRTPNGKL 481 + GAS L+AF+V V +L RL+ FKVP + LPRT GKL Sbjct 453 ADERGASKLRAFVVPAVPDPDPARVEEELIALARRRLAPFKVPRSVELCRALPRTHTGKL 512 Query 482 VRGALRK 488 R A+R Sbjct 513 RRFAVRN 519 >gi|317405901|gb|EFV86183.1| acyl-coenzyme A synthetase [Achromobacter xylosoxidans C54] Length=519 Score = 261 bits (667), Expect = 3e-67, Method: Compositional matrix adjust. Identities = 165/513 (33%), Positives = 254/513 (50%), Gaps = 29/513 (5%) Query 5 NLAGLLAEQASEAGWYDRPAFYAADVVTHGQIHDGAARLGEVLRNRGLSSGDRVLLCLPD 64 +LA L A +A++ + D +T+G++ + AR+ LR GL +R+LL + D Sbjct 13 HLAALNAPRAAKLAYIDD-----TRQLTYGELAERVARMAGALRQLGLRREERILLLMQD 67 Query 65 SPDLVQLLLACLARGVMAFLANPELHRDDHALAARNTEPALVVTSDALRDRFQPSRVAEA 124 + D + L L GV+ N L DD+A ++ S++L Q + Sbjct 68 TADWPVVFLGALHAGVVPVAVNTLLTPDDYAYILNHSRVRAAFVSESLLPTLQAALAQAP 127 Query 125 AEL----MSEAARVAPGGYEPMG---------------GDALAYATYTSGTTGPPKAAIH 165 E+ +S A P G + D +A+ Y+SG+TG PK +H Sbjct 128 GEVEHLVVSRPAAALPAGAHELDALLAAAPLAPAARTLSDEIAFWLYSSGSTGKPKGVVH 187 Query 166 RHADPLTFVDAMCRKALRLTPEDTGLCSARMYFAYGLGNSVWFPLATGGSAVINSAPVTP 225 H + + + L + +D +A+++FAYGLGN + FPL+ G + V+ + TP Sbjct 188 THGNLWHTTELYAKPVLGIREDDIAFSAAKLFFAYGLGNGLTFPLSVGATVVLMAERPTP 247 Query 226 EAAAILSARFGPSVLYGVPNFFARVIDS--CSPDSFRSLRCVVSAGEALELGLAERLMEF 283 +A R P+V YGVP +A ++ + P ++R SAGEAL + ER Sbjct 248 QAVFQRLVRHRPTVFYGVPTLYASMLAAPDLPPREQVAMRVCTSAGEALPRDIGERFQRH 307 Query 284 FGGIPILDGIGSTEVGQTFVSNRVDEWRLGTLGRVLPPYEIRVVAPDGTTAGPGVEGDLW 343 FG ILDGIGSTE+ F+SNR + R GT G+ +P YE+++ +G G G GDL+ Sbjct 308 FG-CDILDGIGSTEMLHIFLSNRAGQLRYGTTGKPVPGYEVQLRDDNGAPVGAGTIGDLY 366 Query 344 VRGPAIAKGYWNRPDSP--VANEGWLDTRDRVCIDSDGWVTYRCRADDTEVIGGVNVDPR 401 ++GP+ A YWN D WL + D+ D+DG+ TY R+DD + G V P Sbjct 367 IKGPSAALMYWNNRDKTRQCFLGDWLKSGDKYICDADGYYTYAGRSDDMIKVSGQYVSPV 426 Query 402 EVERLIIEDEAVAEAAVVAVRESTGASTLQAFLVATSGATIDGSVMRDLHRGLLNRLSAF 461 EVE ++++ EAV EAAV+ V + G +A++V G D + DL R + L+ F Sbjct 427 EVENVLVQHEAVLEAAVIGVPDHDGLVKTKAYVVLRPGYAPDANTGADLQRYVKQHLAPF 486 Query 462 KVPHRFAVVDRLPRTPNGKLVRGALRKQSPTKP 494 K P + D LP+T GK+ R LR+ P Sbjct 487 KYPRQIDFTDELPKTATGKIQRFRLRQLEQVTP 519 >gi|338783457|gb|EGP47823.1| benzoate-coenzyme A ligase [Achromobacter xylosoxidans AXX-A] Length=519 Score = 254 bits (650), Expect = 3e-65, Method: Compositional matrix adjust. Identities = 165/514 (33%), Positives = 251/514 (49%), Gaps = 31/514 (6%) Query 5 NLAGLLAEQASEAGWYDRPAFYAADVVTHGQIHDGAARLGEVLRNRGLSSGDRVLLCLPD 64 +LA L A +A++ + D +T+G++ + AR+ LR GL +RVLL + D Sbjct 13 HLAALNAPRAAKLAYIDD-----TRQLTYGELAERVARMAGALRQLGLRREERVLLLMQD 67 Query 65 SPDLVQLLLACLARGVMAFLANPELHRDDHALAARNTEPALVVTSDALRDRFQPSRVAEA 124 + D + L L GV+ N L DD+A ++ S+ L Q + +A+A Sbjct 68 TADWPVVFLGALHAGVVPVAVNTLLTPDDYAYILDHSRVRAAFVSENLLPTLQAA-LAQA 126 Query 125 AELMSEAARVAPGGYEPMG--------------------GDALAYATYTSGTTGPPKAAI 164 + P P G D +A+ Y+SG+TG PK + Sbjct 127 PGEIEHLVVSRPTAALPPGAHALDALLAAAPLAPAARTLSDEIAFWLYSSGSTGKPKGVV 186 Query 165 HRHADPLTFVDAMCRKALRLTPEDTGLCSARMYFAYGLGNSVWFPLATGGSAVINSAPVT 224 H H + + + L + +D +A+++FAYGLGN + FPL+ G + V+ + T Sbjct 187 HTHGNLWHTAELYAKPVLGIREDDVAFSAAKLFFAYGLGNGLTFPLSVGATVVLMAERPT 246 Query 225 PEAAAILSARFGPSVLYGVPNFFARVIDS--CSPDSFRSLRCVVSAGEALELGLAERLME 282 P+A R P+V YGVP +A ++ + P ++R SAGEAL + ER Sbjct 247 PQAVFQRLVRHRPTVFYGVPTLYASMLAAPDLPPREQVAMRVCTSAGEALPRDIGERFQR 306 Query 283 FFGGIPILDGIGSTEVGQTFVSNRVDEWRLGTLGRVLPPYEIRVVAPDGTTAGPGVEGDL 342 FG ILDGIGSTE+ F+SNR + R GT G+ +P YE+++ +G G GDL Sbjct 307 HFG-CDILDGIGSTEMLHIFISNRAGQLRYGTTGKPVPGYEVQLRDDNGAPVAAGAIGDL 365 Query 343 WVRGPAIAKGYWNRPDSP--VANEGWLDTRDRVCIDSDGWVTYRCRADDTEVIGGVNVDP 400 +++GP+ A YWN D WL + D+ D+DG+ TY R+DD + G V P Sbjct 366 YIKGPSAALMYWNNRDKTRQCFLGDWLKSGDKYLCDADGYYTYAGRSDDMIKVSGQYVSP 425 Query 401 REVERLIIEDEAVAEAAVVAVRESTGASTLQAFLVATSGATIDGSVMRDLHRGLLNRLSA 460 EVE ++++ EAV EAAV+ V + G +A++V G D DL R + L+ Sbjct 426 VEVENVLVQHEAVLEAAVIGVPDHDGLVKTKAYVVLRPGYAPDADTGADLQRYVKQHLAP 485 Query 461 FKVPHRFAVVDRLPRTPNGKLVRGALRKQSPTKP 494 FK P + D LP+T GK+ R LR+ P Sbjct 486 FKYPRQIDFTDELPKTATGKIQRFRLRQLEQVTP 519 >gi|116750059|ref|YP_846746.1| benzoate-CoA ligase family [Syntrophobacter fumaroxidans MPOB] gi|116699123|gb|ABK18311.1| benzoate-CoA ligase family [Syntrophobacter fumaroxidans MPOB] Length=513 Score = 252 bits (644), Expect = 1e-64, Method: Compositional matrix adjust. Identities = 170/478 (36%), Positives = 251/478 (53%), Gaps = 20/478 (4%) Query 25 FYAADVVTHGQIHDGAARLGEVLRNRGLSSGDRVLLCLPDSPDLVQLLLACLARGVMAFL 84 ++ A+ +++ Q+ R G VLR G+S G+R+L+ LPD P+ V L + G L Sbjct 42 YHGAETISYRQLRVRINRFGNVLRGLGVSPGERILIALPDCPECVIAFLGGIKCGAWPVL 101 Query 85 ANPELHRDDHALAARNTEPALVV---TSDALRD--RFQPSRVA----EAAELMSEAA-RV 134 +P+L RD + ++ V TS+ALR R RV + A ++ EA+ + Sbjct 102 LSPQLSRDAYEYILHDSLAVAVFSAGTSEALRADARNLLHRVRADDDDFARMLEEASPEL 161 Query 135 APGGYEPMGGDALAYATYTSGTTGPPKAAIHRHADPLTFVDAMCRKALRLTPEDTGLCSA 194 P P D +A+ Y+SG+TG PK HRH D + A L L+ D ++ Sbjct 162 EP---HPSRKDDIAFMLYSSGSTGKPKGIPHRHRDMVYTAQAYGGGVLGLSENDVCYSAS 218 Query 195 RMYFAYGLGNSVWFPLATGGSAVINSAPVTPEAAAILSARFGPSVLYGVPNFFARVIDSC 254 +++FAYGLGNS+ FPL G S V+ V P + +R+GP++ +GVP + ++ S Sbjct 219 KLFFAYGLGNSLSFPLFHGASVVLYPDAVMPGDVIDIFSRYGPTIFFGVPALYNVLLQSL 278 Query 255 -SPDSFRSLRCVVSAGEALELGLAERLMEFFGGIPILDGIGSTEVGQTFVSNRVDEWRLG 313 P F SLR VSAGEAL + R E F G+ +LDGIG+TEV F+SNR E R G Sbjct 279 DQPVRFPSLRLCVSAGEALPATVCSRWRE-FTGLDVLDGIGTTEVLHIFISNRPGEVRPG 337 Query 314 TLGRVLPPYEIRVVAPDGTTAGPGVEGDLWVRGPAIAKGYWNRPDS---PVANEGWLDTR 370 T G V+PPYE R+V G G G L +RG + A YWN+P+ + +GWL T Sbjct 338 TSGFVVPPYEARIVDDGGNDLAAGQPGRLLIRGLSTAPFYWNQPEKTSETMLRDGWLHTG 397 Query 371 DRVCIDSDGWVTYRCRADDTEVIGGVNVDPREVERLIIEDEAVAEAAVVAVRESTGASTL 430 D + ++ G TY+ RADD +GG V VE++I E AV+E AV RE G + Sbjct 398 D-IFVEEAGCYTYQGRADDMFKVGGNWVSTSRVEQVIREHPAVSECAVTW-REFEGFARP 455 Query 431 QAFLVATSGATIDGSVMRDLHRGLLNRLSAFKVPHRFAVVDRLPRTPNGKLVRGALRK 488 AF+ G + + + ++ ++ RL + P + LP+T GK+ R LR+ Sbjct 456 VAFVALAPGVSEESRLSGEIRSHVMERLPGYMCPAQIEFRATLPKTETGKIQRYRLRR 513 >gi|256377631|ref|YP_003101291.1| AMP-dependent synthetase and ligase [Actinosynnema mirum DSM 43827] gi|255921934|gb|ACU37445.1| AMP-dependent synthetase and ligase [Actinosynnema mirum DSM 43827] Length=503 Score = 251 bits (640), Expect = 4e-64, Method: Compositional matrix adjust. Identities = 202/490 (42%), Positives = 252/490 (52%), Gaps = 17/490 (3%) Query 5 NLAGLLAEQASEAGWYDRPAF-YAADVVTHGQIHDGAARLGEVLRNRGLSSGDRVLLCLP 63 NLA LL +AS GW R AF + VTHG++H A L G+ GDRV+L L Sbjct 19 NLAELLRVRASGRGWSGRVAFECGGERVTHGEVHARAVVRSAALAALGVRVGDRVVLVLD 78 Query 64 DSPDLVQLLLACLARGVMAFLANPELHRDDHALAARNTEPALVVTSDALRDRFQPSRVAE 123 D D V L LA L G +A NP LHR + A E ALVV R R P Sbjct 79 DDVDFVVLFLAVLRLGAVAVPVNPRLHRGELAACLTAAEAALVVR----RPRDAPELAGR 134 Query 124 AAELMSEAARVAPGGYEPMGGDALAYATYTSGTTGPPKAAIHRHADPLTFVDAMCRKALR 183 + A + + AYA +TSGTTG + H HADPL + A LR Sbjct 135 TPADLDFPAPPV--PAAALPDEHPAYALFTSGTTGASRLCPHAHADPLVYQRAFGGPVLR 192 Query 184 LTPEDTGLCSARMYFAYGLGNSVWFPLATGGSAVINSAPVTPEAAAILSARFGPSVLYGV 243 LTP+D ++MYFAYGLGNS+ +PL G AV+ + P A L SVL+ V Sbjct 193 LTPDDVVHSVSKMYFAYGLGNSLLYPLLAGCRAVLEAGPPQAARALALVDEHRVSVLFSV 252 Query 244 PNFFARVIDSCSPDSFRSLRCVVSAGEALELGLAERLMEFFGGIPILDGIGSTEVGQTFV 303 P F++R++ + LR V+AGE L L L RL G +L+GIG+TEVGQ F Sbjct 253 PTFYSRLLTEPACGLLAGLRLAVTAGEVLPLSLERRLGALLGE-RLLNGIGTTEVGQAFT 311 Query 304 SNRVDEWRLGTLGRVLPPYEIRVVAPDGTTAGPGVEGDLWVRGPAIAKGYWNRPD-SPVA 362 SN R+GT+GR LPPY +RVV G G V G L VRGP ++ G RPD P Sbjct 312 SNAAGAHRIGTVGRALPPYAVRVVDELGAVVGADVVGRLQVRGPTVSAG--ARPDGGPGR 369 Query 363 NEGWLDTRDRVCIDSDGWVTYRCRADDTEVIGGVNVDPREVERLIIEDEAVAEAAVVAVR 422 GW T D D+DG++ RADD E +GG+ V P +VE L+ E VAEAAV AVR Sbjct 370 EPGWYTTGDLASCDADGYLVVTGRADDIENVGGIKVHPVDVESLLAEHPLVAEAAVCAVR 429 Query 423 ESTGASTLQAFLV-ATSGATIDGSVMRDLHRGLLNR----LSAFKVPHRFAVVDRLPRTP 477 E G S L+A++V A G G +L LL LS +K P V LPRT Sbjct 430 EG-GRSWLRAYVVRAGGGPGDGGPDDGELAEELLATARAGLSTYKAPRAVVFVPALPRTG 488 Query 478 NGKLVRGALR 487 +GKL R +R Sbjct 489 SGKLRRHVVR 498 >gi|138895541|ref|YP_001125994.1| benzoate-CoA ligase [Geobacillus thermodenitrificans NG80-2] gi|196249697|ref|ZP_03148394.1| benzoate-CoA ligase family [Geobacillus sp. G11MC16] gi|134267054|gb|ABO67249.1| Benzoate-CoA ligase [Geobacillus thermodenitrificans NG80-2] gi|196210991|gb|EDY05753.1| benzoate-CoA ligase family [Geobacillus sp. G11MC16] Length=529 Score = 250 bits (639), Expect = 5e-64, Method: Compositional matrix adjust. Identities = 151/517 (30%), Positives = 247/517 (48%), Gaps = 34/517 (6%) Query 2 RNGNLAGLLAEQASEAGWYDRPAFYAAD-VVTHGQIHDGAARLGEVLRNRGLSSGDRVLL 60 R N AGL + +G D+ A Y D +++ + + + G +LR G DR+++ Sbjct 8 RLYNAAGLFIDHHVHSGLGDKTAIYYRDEQISYRTLQEKVNQAGNMLRELGYKLEDRLIM 67 Query 61 CLPDSPDLVQLLLACLARGVMAFLANPELHRDDHALAARNTEPALVVTSDALRDRFQPSR 120 D+P+ + + G + N + D+ N+ +V + L ++ +P+R Sbjct 68 VCHDTPEFIYTFFGAIKIGAVPIPVNTMMQSSDYEYFLNNSRAKGLVIHEDLWEQLEPAR 127 Query 121 -----------VAEAA-----------ELMSEAARVAPGGYEPMGGDALAYATYTSGTTG 158 + E+A +L+ AA+ P D A+ ++SG+TG Sbjct 128 ERFAFLEHVIVIYESANKVLEGTLSYHQLIHRAAKELTAA--PTNKDDAAFWLFSSGSTG 185 Query 159 PPKAAIHRHADPLTFVDAMCRKALRLTPEDTGLCSARMYFAYGLGNSVWFPLATGGSAVI 218 PK IH D ++ ++ L + D L ++++YFAYGLG ++FPL +G S V+ Sbjct 186 EPKGVIHLQHDMEYALNTYAKQVLEMNEHDRCLSASKLYFAYGLGGGMYFPLGSGASTVL 245 Query 219 NSAPVTPEAAAILSARFGPSVLYGVPNFFARVIDSCSPD----SFRSLRCVVSAGEALEL 274 PE + P++ +GVP + +ID RSLR VSAGEAL Sbjct 246 IKERPLPETMFQAIETYKPTIFFGVPTLYGAMIDYVEKTGRQFDVRSLRVCVSAGEALPP 305 Query 275 GLAERLMEFFGGIPILDGIGSTEVGQTFVSNRVDEWRLGTLGRVLPPYEIRVVAPDGTTA 334 + + F G+ ILDGIGSTE F+SNR+ + + G+ G+ +P Y+++++ G Sbjct 306 SFYYKWKKLF-GVDILDGIGSTEALHIFISNRIGDVKPGSSGKAVPGYDVKIIDGQGNEL 364 Query 335 GPGVEGDLWVRGPAIAKGYWN---RPDSPVANEGWLDTRDRVCIDSDGWVTYRCRADDTE 391 P GDL +RG ++A GYWN + E WL D+ D +G+ Y R+DD Sbjct 365 PPNEVGDLIIRGDSVAHGYWNLHEQNKQKFVGE-WLYIGDKYYRDEEGYYWYCGRSDDML 423 Query 392 VIGGVNVDPREVERLIIEDEAVAEAAVVAVRESTGASTLQAFLVATSGATIDGSVMRDLH 451 +GG+ V P E+E +++ E V E AVV V G + +AF+V G T +L Sbjct 424 KVGGIWVSPIEIENCLLQHEDVLEVAVVGVDNEKGLTVPKAFVVLKDGVTPSAKKEEELK 483 Query 452 RGLLNRLSAFKVPHRFAVVDRLPRTPNGKLVRGALRK 488 + +L+ +K P +D LP+T GK+ R LR+ Sbjct 484 QFTKQQLAHYKYPRIIEFIDELPKTATGKIQRFKLRQ 520 >gi|163857887|ref|YP_001632185.1| acyl-coenzyme A synthetase [Bordetella petrii DSM 12804] gi|163261615|emb|CAP43917.1| probable acyl-coenzyme A synthetases [Bordetella petrii] Length=519 Score = 250 bits (638), Expect = 7e-64, Method: Compositional matrix adjust. Identities = 168/510 (33%), Positives = 247/510 (49%), Gaps = 35/510 (6%) Query 5 NLAGLLAEQASEAGWYDRPAFYAADVVTHGQIHDGAARLGEVLRNRGLSSGDRVLLCLPD 64 +LA L A +A++ + D +T+G++ + AR LR GL +RVLL + D Sbjct 13 HLAALNAPRAAKLAYIDD-----TRRLTYGELAERVARCAGALRQMGLRREERVLLLMHD 67 Query 65 SPDLVQLLLACLARGVMAFLANPELHRDDHALAARNTEPALVVTSDALRDRFQPSRVAEA 124 S D L L GV+ N L DD+A A ++ + S L D Q + +A+ Sbjct 68 SVDWPVTFLGALHAGVVPVAINTLLTPDDYAYIASHSRARAAIVSGTLVDTLQ-AALAKG 126 Query 125 AELMSEAARVAPGGYEPMGG--------------------DALAYATYTSGTTGPPKAAI 164 + P G P D +A+ Y+SG+TG PK + Sbjct 127 PHEIEHIVVAQPAGPLPAQAREFDSLLAGAPLMPAVRTLADEIAFWLYSSGSTGKPKGVV 186 Query 165 HRHADPLTFVDAMCRKALRLTPEDTGLCSARMYFAYGLGNSVWFPLATGGSAVINSAPVT 224 H H + V+ + L + +D +A+++FAYGLGN + FPL+ G + V+ T Sbjct 187 HTHGNLWHTVELYAKPVLGIREDDVVFSAAKLFFAYGLGNGLSFPLSVGATVVVMGERPT 246 Query 225 PEAAAILSARFGPSVLYGVPNFFARVIDSCSPD----SFRSLRCVVSAGEALELGLAERL 280 P+A PSV YGVP +A ++ SPD +LR SAGEAL + ER Sbjct 247 PQAVFKRLTEHRPSVFYGVPTLYASML--ASPDLPAREQVALRVCTSAGEALPRDIGERF 304 Query 281 MEFFGGIPILDGIGSTEVGQTFVSNRVDEWRLGTLGRVLPPYEIRVVAPDGTTAGPGVEG 340 F G ILDGIGSTE+ F+SN+ + R GT G+ +P YE+++ +G P G Sbjct 305 TRHF-GCEILDGIGSTEMLHIFLSNQPGQLRYGTTGKPVPGYEVQLRDDEGRPVPPNAIG 363 Query 341 DLWVRGPAIAKGYWNRPDS--PVANEGWLDTRDRVCIDSDGWVTYRCRADDTEVIGGVNV 398 DL+++GP+ A YWN D WL + D+ D+DG+ TY R+DD + G V Sbjct 364 DLYIKGPSAALMYWNNRDKTRQCFQGEWLKSGDKYQCDADGYYTYAGRSDDMIKVSGQYV 423 Query 399 DPREVERLIIEDEAVAEAAVVAVRESTGASTLQAFLVATSGATIDGSVMRDLHRGLLNRL 458 P EVE ++I+ EAV EAAV+ V + G +A++V G D L + L Sbjct 424 SPVEVENVLIQHEAVLEAAVIGVPDHDGLVKTKAYVVLRPGFQPDAGTGAALQSYVKQHL 483 Query 459 SAFKVPHRFAVVDRLPRTPNGKLVRGALRK 488 + FK P + D LP+T GK+ R LR+ Sbjct 484 APFKYPRQINFTDELPKTATGKIQRFRLRQ 513 >gi|311108203|ref|YP_003981056.1| benzoate-coenzyme A ligase [Achromobacter xylosoxidans A8] gi|310762892|gb|ADP18341.1| benzoate-coenzyme A ligase [Achromobacter xylosoxidans A8] Length=519 Score = 249 bits (636), Expect = 1e-63, Method: Compositional matrix adjust. Identities = 161/508 (32%), Positives = 249/508 (50%), Gaps = 31/508 (6%) Query 5 NLAGLLAEQASEAGWYDRPAFYAADVVTHGQIHDGAARLGEVLRNRGLSSGDRVLLCLPD 64 +LA L A +A++ + D +++G++ + AR+ LR GL +R+LL + D Sbjct 13 HLAALNAPRAAKPAYIDD-----TRQISYGELAERVARMAGALRQLGLRREERILLLMQD 67 Query 65 SPDLVQLLLACLARGVMAFLANPELHRDDHALAARNTEPALVVTSDALRDRFQPSRVAEA 124 S D + L L GV+ N L DD+A ++ + V S L Q + +A+A Sbjct 68 SVDWPVVFLGALHAGVVPVAVNTLLTADDYAYIIGHSRVSAVFASGTLLPVVQAA-LAQA 126 Query 125 AELMSEAARVAPGGYEPMGG--------------------DALAYATYTSGTTGPPKAAI 164 + + P G P D +A+ Y+SG+TG PK + Sbjct 127 SADVEHLVVSQPAGPLPEAAREFESLLAAAPLAPAARTLSDEIAFWLYSSGSTGKPKGVV 186 Query 165 HRHADPLTFVDAMCRKALRLTPEDTGLCSARMYFAYGLGNSVWFPLATGGSAVINSAPVT 224 H H + + + L + +D +A+++FAYGLGN + FPL+ G + ++ T Sbjct 187 HTHGNLWHTAELYAKPVLGIREDDVVFSAAKLFFAYGLGNGLTFPLSVGATVILMGERPT 246 Query 225 PEAAAILSARFGPSVLYGVPNFFARVIDS--CSPDSFRSLRCVVSAGEALELGLAERLME 282 P+A R P+V YGVP +A ++ S P ++R SAGEAL + ER Sbjct 247 PQAVFQRLTRHRPTVFYGVPTLYASMLASPDLPPREQVAMRICTSAGEALPRDIGERYTR 306 Query 283 FFGGIPILDGIGSTEVGQTFVSNRVDEWRLGTLGRVLPPYEIRVVAPDGTTAGPGVEGDL 342 F G ILDGIGSTE+ F+SN+ + R GT G+ +P YE+++ G PG GDL Sbjct 307 HF-GCEILDGIGSTEMLHIFISNQTGQLRYGTTGKPVPGYEVQLRDDSGALVPPGAIGDL 365 Query 343 WVRGPAIAKGYWNRPDSP--VANEGWLDTRDRVCIDSDGWVTYRCRADDTEVIGGVNVDP 400 +++GP+ A YWN D WL + D+ D+DG+ TY R+DD + G V P Sbjct 366 YIKGPSAALMYWNNRDKTRQCFLGDWLKSGDKYTCDADGYYTYAGRSDDMIKVSGQYVSP 425 Query 401 REVERLIIEDEAVAEAAVVAVRESTGASTLQAFLVATSGATIDGSVMRDLHRGLLNRLSA 460 EVE ++++ EAV EAAV+ V + G +A++V G D L + L+ Sbjct 426 VEVENILVQHEAVLEAAVIGVPDHDGLVKTKAYVVLRPGFEPDAQTGAALQNYVKQHLAP 485 Query 461 FKVPHRFAVVDRLPRTPNGKLVRGALRK 488 FK P + + LP+T GK+ R LR+ Sbjct 486 FKYPRQINFTEELPKTATGKIQRFRLRQ 513 >gi|293607059|ref|ZP_06689402.1| benzoate-coenzyme A ligase [Achromobacter piechaudii ATCC 43553] gi|292814549|gb|EFF73687.1| benzoate-coenzyme A ligase [Achromobacter piechaudii ATCC 43553] Length=531 Score = 248 bits (632), Expect = 3e-63, Method: Compositional matrix adjust. Identities = 156/493 (32%), Positives = 239/493 (49%), Gaps = 36/493 (7%) Query 31 VTHGQIHDGAARLGEVLRNRGLSSGDRVLLCLPDSPDLVQLLLACLARGVMAFLANPELH 90 +T+GQ+ + AR+ LR GL +R+LL + D+ D + L L GV+ N L Sbjct 34 LTYGQLAERVARMAGALRQLGLRREERILLLMQDTVDWPVVFLGALHAGVVPVAVNTLLT 93 Query 91 RDDHALAARNTEPALVVTSDALRDRFQPSRVAEAAEL----MSEAARVAPGGYEPMG--- 143 DD+A ++ V S AL Q + ++ +S+ P +P+ Sbjct 94 PDDYAYIVTHSRVRAVFASGALLPTLQAALAQTPGDVEHVVVSQPVDTQPVVSQPVDTPS 153 Query 144 ------------------------GDALAYATYTSGTTGPPKAAIHRHADPLTFVDAMCR 179 D +A+ Y+SG+TG PK +H H + + + Sbjct 154 ADIDTLDFEALLAAAPLAPAVRTLSDEIAFWLYSSGSTGKPKGVVHTHGNLWHTAELYAK 213 Query 180 KALRLTPEDTGLCSARMYFAYGLGNSVWFPLATGGSAVINSAPVTPEAAAILSARFGPSV 239 L + +D +A+++FAYGLGN + FPL+ G + ++ TP+A R P+V Sbjct 214 PVLGIREDDVVFSAAKLFFAYGLGNGLTFPLSVGATVILMGERPTPQAVFQRLTRHRPTV 273 Query 240 LYGVPNFFARVIDS--CSPDSFRSLRCVVSAGEALELGLAERLMEFFGGIPILDGIGSTE 297 YGVP +A ++ S P ++R SAGEAL + ER FG ILDGIGSTE Sbjct 274 FYGVPTLYASMLASPELPPREQVAMRVCTSAGEALPRDIGERFTRHFG-CEILDGIGSTE 332 Query 298 VGQTFVSNRVDEWRLGTLGRVLPPYEIRVVAPDGTTAGPGVEGDLWVRGPAIAKGYWNRP 357 + F+SN+ + R GT G+ +P YE+++ G PG GDL+++GP+ A YWN Sbjct 333 MLHIFISNQTGQLRYGTTGKPVPGYEVQLRDDSGAPVAPGAIGDLYIKGPSAALMYWNNR 392 Query 358 DSP--VANEGWLDTRDRVCIDSDGWVTYRCRADDTEVIGGVNVDPREVERLIIEDEAVAE 415 D WL + D+ D+DG+ TY R+DD + G V P EVE ++++ EAV E Sbjct 393 DKTRQCFLGDWLKSGDKYTCDADGYYTYAGRSDDMIKVSGQYVSPVEVENILVQHEAVLE 452 Query 416 AAVVAVRESTGASTLQAFLVATSGATIDGSVMRDLHRGLLNRLSAFKVPHRFAVVDRLPR 475 AAV+ V + G +A++V G D L R + L+ FK P + + LP+ Sbjct 453 AAVIGVPDHDGLVKTKAYVVLRPGFEPDEQTGAALQRYVKQHLAPFKYPRQINFTEELPK 512 Query 476 TPNGKLVRGALRK 488 T GK+ R LR+ Sbjct 513 TATGKIQRFRLRQ 525 >gi|299533431|ref|ZP_07046813.1| benzoate-CoA ligase family protein [Comamonas testosteroni S44] gi|298718637|gb|EFI59612.1| benzoate-CoA ligase family protein [Comamonas testosteroni S44] Length=520 Score = 243 bits (619), Expect = 1e-61, Method: Compositional matrix adjust. Identities = 160/486 (33%), Positives = 244/486 (51%), Gaps = 31/486 (6%) Query 30 VVTHGQIHDGAARLGEVLRNRGLSSGDRVLLCLPDSPDLVQLLLACLARGVMAFLANPEL 89 +++ Q+ + A RL L G+ +RVLL + D + V L + GV+ N L Sbjct 33 TLSYAQLQEQARRLAHGLLAAGIHREERVLLVMHDMREWVISFLGAMYAGVVPVAVNTLL 92 Query 90 HRDDHALAARNTEPALVVTSDALRDRFQPSRVAEAAELMS-------EAARVAPGGYEPM 142 D+A + +VT+ AL Q + E+ EA + P +EP+ Sbjct 93 TAADYAYMLEHCRAQAIVTNGALVAVVQQALEQAQHEVNHIWVARPDEAPQGLPPAFEPL 152 Query 143 G----------------GDALAYATYTSGTTGPPKAAIHRHADPLTFVDAMCRKALRLTP 186 GD + Y+SG+TG PK A+H HA+P + + L L Sbjct 153 QPWLQQQMPLAHAARTMGDDPGFWLYSSGSTGKPKGAVHTHANPYWTAELYGKPVLGLNA 212 Query 187 EDTGLCSARMYFAYGLGNSVWFPLATGGSAVINSAPVTPEAAAILSARFGPSVLYGVPNF 246 D +A++YFAYGLGN++ FPL+ G S V+ + TPEA P+V +G P Sbjct 213 NDVCFSAAKLYFAYGLGNALTFPLSVGASVVLMAERPTPEATFRRWTEHQPTVFFGAPTG 272 Query 247 FARVIDSCSPDSFR--SLRCVVSAGEALELGLAERLMEFFGGIPILDGIGSTEVGQTFVS 304 FA ++ + + SLR SAGEAL +A+R FG I+DGIGSTE+ F+S Sbjct 273 FAGMLAHPTLPAREQVSLRMCSSAGEALPAEIAQRFKTHFGA-DIVDGIGSTEMLHIFLS 331 Query 305 NRVDEWRLGTLGRVLPPYEIRVVAPDGTTAGPGVEGDLWVRGPAIAKGYW-NRPDSPVAN 363 NR D+ R G+ G+ +P Y + + DG G GDL+++GP+ A YW NR + Sbjct 332 NRPDDIRYGSTGKPVPGYAVELRGEDGQPVADGEIGDLYIKGPSAALMYWANRDKTRDTF 391 Query 364 EG-WLDTRDRVCIDSDGWVTYRCRADDTEVIGGVNVDPREVERLIIEDEAVAEAAVVAVR 422 +G WL + D+ D+DG+ TY R+DD + G+ V P EVE + + AV EAAV+ V Sbjct 392 QGAWLKSGDKYVRDADGYYTYAGRSDDMLKVSGIYVSPFEVESTLQQHPAVLEAAVIGVT 451 Query 423 ESTGASTLQAFLVATSGATIDGSVMRDLHRGLLNRLSAFKVPHRFAVVDRLPRTPNGKLV 482 + G + ++++V G + + ++ + NRL+A+K P VD LP+T GK+ Sbjct 452 DEQGLTKTKSYVVCKPGQSASEAELKAF---VKNRLAAYKYPRFIEFVDELPKTATGKIQ 508 Query 483 RGALRK 488 R LR+ Sbjct 509 RFRLRE 514 >gi|300245891|gb|ADJ94003.1| putative benzoate-CoA ligase BzlA [Clostridia bacterium enrichment culture clone BF] Length=541 Score = 242 bits (618), Expect = 2e-61, Method: Compositional matrix adjust. Identities = 150/510 (30%), Positives = 245/510 (49%), Gaps = 23/510 (4%) Query 2 RNGNLAGLLAEQASEAGWYDRPAFYAAD-VVTHGQIHDGAARLGEVLRNRGLSSGDRVLL 60 N N ++ G D+ A Y D +++ ++ + G N G+ + DR+LL Sbjct 32 ENYNAVSFFVDRHLAEGRGDKTAIYYLDQKISYREVAANVNKTGNAFLNLGIETEDRILL 91 Query 61 CLPDSPDLVQLLLACLARGVMAFLANPELHRDDHALAARNTEPALVVTSDALRDRF-QPS 119 L D P+ V + G + N L D+ +++ VV S+ L + + S Sbjct 92 LLLDCPEFVYSFFGAIKIGAVPIPTNTMLKPTDYEYLLKDSRAKAVVVSEELIENINEIS 151 Query 120 RVAEAAELMSEAARVAPG---------------GYEPMGGDALAYATYTSGTTGPPKAAI 164 + E + R PG P D + Y+SGTTG PK A+ Sbjct 152 SNLPSVEHIIVVGRSGPGQLSFHNLIKNASPVLSLAPTIKDDPCFWLYSSGTTGFPKGAV 211 Query 165 HRHADPLTFVDAMCRKALRLTPEDTGLCSARMYFAYGLGNSVWFPLATGGSAVINSAPVT 224 H D + + +K L + +D A+++FAYGLGN ++FP + G + V++ Sbjct 212 HLQHDMVYCAENYAQKVLNINEDDVTFSVAKLFFAYGLGNGLYFPFSVGAATVLSPQRPL 271 Query 225 PEAAAILSARFGPSVLYGVPNFFARVIDSCSPDS---FRSLRCVVSAGEALELGLAERLM 281 PE + R+ PS+ +GVP + ++ ++ S+R VSAGE L + +R M Sbjct 272 PEHVFEVIERYRPSLFFGVPTSYNALLQLAEEENKYDLSSIRSCVSAGETLPEIIYQRWM 331 Query 282 EFFGGIPILDGIGSTEVGQTFVSNRVDEWRLGTLGRVLPPYEIRVVAPDGTTAGPGVEGD 341 E F G+ ILDGIGSTE+ F+SNR E + G+ GR++P YE +++ DG +G Sbjct 332 EIF-GLEILDGIGSTEILHIFISNRPGETKPGSSGRLVPGYEAKILDEDGCEVPTEEQGT 390 Query 342 LWVRGPAIAKGYWNRPDSPVANE--GWLDTRDRVCIDSDGWVTYRCRADDTEVIGGVNVD 399 L+++G +IA YWN+ + W++T DR D DG+ Y R DD GG+ V Sbjct 391 LYIKGDSIASYYWNKHEKSKQTFVGEWINTGDRYYRDKDGYFWYMGRGDDMIKSGGIWVS 450 Query 400 PREVERLIIEDEAVAEAAVVAVRESTGASTLQAFLVATSGATIDGSVMRDLHRGLLNRLS 459 EVE +++ AV E AV +S G +AF+V + ++ +L + + N+++ Sbjct 451 LVEVESTLLQHPAVLECAVTGWADSDGLIKPKAFVVLKQNSHETQALAEELQQFVKNKIA 510 Query 460 AFKVPHRFAVVDRLPRTPNGKLVRGALRKQ 489 +K P +D LP+T GK+ R LR++ Sbjct 511 PYKYPRWLEFIDELPKTATGKIQRYKLRQE 540 >gi|194289443|ref|YP_002005350.1| benzoate-CoA ligase [Cupriavidus taiwanensis LMG 19424] gi|193223278|emb|CAQ69283.1| Benzoate-CoA ligase [Cupriavidus taiwanensis LMG 19424] Length=535 Score = 242 bits (617), Expect = 2e-61, Method: Compositional matrix adjust. Identities = 168/483 (35%), Positives = 245/483 (51%), Gaps = 27/483 (5%) Query 31 VTHGQIHDGAARLGEVLRNRGLSSGDRVLLCLPDSPDLVQLLLACLARGVMAFLANPELH 90 +T+ ++ D + R LR GL +RVLLC D+ D + L CL GV+ N L Sbjct 50 LTYAELDDRSRRFSGALRAAGLRQEERVLLCALDTVDFPVVFLGCLLAGVVPVAVNTLLT 109 Query 91 RDDHAL--------AARNTEPALVVTSDALRDR------FQPSRVAEAAELMSEAARVA- 135 DD+A A +EP L V A+ Q + A AA S A +A Sbjct 110 ADDYAYMLDHSGARAVVVSEPLLAVMQAAIDKSGLAPTVIQAAPHAGAAPSCSVGAMLAR 169 Query 136 ---PGGYEPMGGDALAYATYTSGTTGPPKAAIHRHADPLTFVDAMCRKALRLTPEDTGLC 192 P G D +A+ Y+SG+TG PK +H HA+ D R+ L + +D Sbjct 170 TRTPATAASTGPDDMAFWLYSSGSTGRPKGTVHTHANLFHTADLYARQVLGIREDDVVFS 229 Query 193 SARMYFAYGLGNSVWFPLATGGSAVINSAPVTPEAAAILSARFGPSVLYGVPNFFARVID 252 +A+++FAYGLGN++ FP++ G + V+ + TP A P+V GVP FA ++ Sbjct 230 AAKLFFAYGLGNALTFPMSVGATTVLMAERPTPAAVFKRLREHQPTVFCGVPTLFAGML- 288 Query 253 SCSPD----SFRSLRCVVSAGEALELGLAERLMEFFGGIPILDGIGSTEVGQTFVSNRVD 308 +PD + +LR SAGEAL + ER + F G ILDGIGSTE+ F+SNR Sbjct 289 -AAPDLPARADVALRVCTSAGEALPRDIGERFLAHF-GCDILDGIGSTEMLHIFLSNRPG 346 Query 309 EWRLGTLGRVLPPYEIRVVAPDGTTAGPGVEGDLWVRGPAIAKGYW-NRPDSPVANEG-W 366 R GT G +P YEIR++ G G G+L+++GP+ A YW NR S G W Sbjct 347 AVRYGTTGVPVPGYEIRLLDEQGQPCAAGEIGELFIKGPSAALMYWCNRDKSRETFVGAW 406 Query 367 LDTRDRVCIDSDGWVTYRCRADDTEVIGGVNVDPREVERLIIEDEAVAEAAVVAVRESTG 426 + D+ D+DG+ TY R+DD +GG+ V P EVE + + AV EAAV+ V ++ Sbjct 407 TRSGDKYLRDADGYYTYAGRSDDMLKVGGIYVSPFEVEAALAQHPAVLEAAVIGVTDADE 466 Query 427 ASTLQAFLVATSGATIDGSVMRDLHRGLLNRLSAFKVPHRFAVVDRLPRTPNGKLVRGAL 486 +AF+V G + +L + +RL+ +K P + V LP+T GK+ R L Sbjct 467 LVKPKAFVVLRPGQQWHDGMAAELQAFVKSRLAPYKYPRQIECVPELPKTATGKIQRFRL 526 Query 487 RKQ 489 R++ Sbjct 527 RQR 529 >gi|113867426|ref|YP_725915.1| benzoate-coenzyme A ligase [Ralstonia eutropha H16] gi|113526202|emb|CAJ92547.1| Benzoate-coenzyme A ligase [Ralstonia eutropha H16] Length=551 Score = 242 bits (617), Expect = 2e-61, Method: Compositional matrix adjust. Identities = 164/481 (35%), Positives = 245/481 (51%), Gaps = 23/481 (4%) Query 31 VTHGQIHDGAARLGEVLRNRGLSSGDRVLLCLPDSPDLVQLLLACLARGVMAFLANPELH 90 +T+ ++ A R LR+ GL +R+LLC D+ D + L CL GV+ N L Sbjct 63 LTYAELDARARRFAGALRDAGLRQEERLLLCALDTIDFPTVFLGCLLAGVVPVAVNTLLT 122 Query 91 RDDHAL--------AARNTEPALVVTSDALRDR------FQPSRVAEAAELMSEAARVA- 135 DD+A A +EP L V A+ Q + A+ A S A +A Sbjct 123 ADDYAYMLGHSGARAVVVSEPLLPVMKAAIDKSGLAPMVIQAAPHADGAPACSVGAMLAR 182 Query 136 ---PGGYEPMGGDALAYATYTSGTTGPPKAAIHRHADPLTFVDAMCRKALRLTPEDTGLC 192 P G D +A+ Y+SG+TG PK +H H + D R+ L + +D Sbjct 183 TRSPAQAVRSGPDDMAFWLYSSGSTGRPKGTVHTHGNLFHTADLYARQVLGIREDDVVFS 242 Query 193 SARMYFAYGLGNSVWFPLATGGSAVINSAPVTPEAAAILSARFGPSVLYGVPNFFARVID 252 +A+++FAYGLGN++ FP++ G + V+ + TP A P+V GVP FA ++ Sbjct 243 AAKLFFAYGLGNALTFPMSVGATTVLMAERPTPAAVFRRLREQRPTVFCGVPTLFAGMLA 302 Query 253 S--CSPDSFRSLRCVVSAGEALELGLAERLMEFFGGIPILDGIGSTEVGQTFVSNRVDEW 310 + P + +LR SAGEAL + ER + F G ILDGIGSTE+ F+SNR E Sbjct 303 APELPPRAEVALRVCTSAGEALPRDIGERFLAHF-GCDILDGIGSTEMLHIFLSNRPGEV 361 Query 311 RLGTLGRVLPPYEIRVVAPDGTTAGPGVEGDLWVRGPAIAKGYW-NRPDSPVANEG-WLD 368 R GT G+ +P Y ++++ G PG GDL+++GP+ A YW NR S G W Sbjct 362 RYGTTGKPVPGYALKLLDERGEPCAPGEIGDLYIKGPSAALMYWCNRDKSRDTFVGEWTR 421 Query 369 TRDRVCIDSDGWVTYRCRADDTEVIGGVNVDPREVERLIIEDEAVAEAAVVAVRESTGAS 428 + D+ D+DG+ TY R+DD +GG+ V P EVE + + AV EAAV+ V ++ Sbjct 422 SGDKYLCDADGYYTYAGRSDDMLKVGGIYVSPFEVEAALAQHPAVLEAAVIGVTDADELV 481 Query 429 TLQAFLVATSGATIDGSVMRDLHRGLLNRLSAFKVPHRFAVVDRLPRTPNGKLVRGALRK 488 +AF+V G + +L + +RL+ +K P + V LP+T GK+ R LR+ Sbjct 482 KPKAFVVLRPGQQWHDGMAAELQAFIKSRLAPYKYPRQIECVPELPKTATGKIQRFRLRQ 541 Query 489 Q 489 + Sbjct 542 R 542 >gi|94310169|ref|YP_583379.1| benzoate-CoA ligase family [Cupriavidus metallidurans CH34] gi|93354021|gb|ABF08110.1| Benzoate-CoA ligase family [Cupriavidus metallidurans CH34] Length=549 Score = 241 bits (615), Expect = 4e-61, Method: Compositional matrix adjust. Identities = 161/483 (34%), Positives = 243/483 (51%), Gaps = 25/483 (5%) Query 31 VTHGQIHDGAARLGEVLRNRGLSSGDRVLLCLPDSPDLVQLLLACLARGVMAFLANPELH 90 +T ++ D R L G +RVLLC D+ D + L CL GV+ N L Sbjct 61 LTFAELDDRCRRFAGALLRAGFRREERVLLCAFDTIDFPTVFLGCLLAGVVPVAVNTLLT 120 Query 91 RDDHALAARNTEPALVVTSDALRDRFQPSRV------------------AEAAELMSEAA 132 +D+A ++ VV S L + + A+AA +S A Sbjct 121 TEDYAYMLEHSGARAVVVSAQLLPTMRAAMTKAGVTPDLIVAAPHTEDSAKAANTVSAMA 180 Query 133 RVAPGGYEPM--GGDALAYATYTSGTTGPPKAAIHRHADPLTFVDAMCRKALRLTPEDTG 190 AP + + G D +A+ Y+SG+TG PK +H H + D R+ L + +DT Sbjct 181 ASAPPLAQSVATGPDDMAFWLYSSGSTGRPKGTVHTHGNLFHTADLYARRVLGIREDDTV 240 Query 191 LCSARMYFAYGLGNSVWFPLATGGSAVINSAPVTPEAAAILSARFGPSVLYGVPNFFARV 250 +A+++FAYGLGN++ FPLA G + ++ + TP+A P+V GVP FA + Sbjct 241 FSAAKLFFAYGLGNALTFPLAVGATTILMAERPTPQAVFQRLTTHRPTVFCGVPTLFAGM 300 Query 251 IDS--CSPDSFRSLRCVVSAGEALELGLAERLMEFFGGIPILDGIGSTEVGQTFVSNRVD 308 + S P + ++R SAGEAL + R + F G ILDGIGSTE+ F+SNR Sbjct 301 LASPDLPPRADVAMRVCTSAGEALPQDIGNRFLAHF-GCDILDGIGSTEMLHIFLSNRPG 359 Query 309 EWRLGTLGRVLPPYEIRVVAPDGTTAGPGVEGDLWVRGPAIAKGYW-NRPDSPVANEG-W 366 E R GT G+ +P YE++++ G G GDL+++GP+ A YW NR S G W Sbjct 360 EVRYGTTGKPVPGYELKLLDERGEPCASGEVGDLYIKGPSAALMYWCNREKSRDTFVGAW 419 Query 367 LDTRDRVCIDSDGWVTYRCRADDTEVIGGVNVDPREVERLIIEDEAVAEAAVVAVRESTG 426 + D+ D+DG+ TY R+DD +GG+ V P EVE + AV EAAV+ V ++ Sbjct 420 TRSGDKYVCDADGYFTYAGRSDDMLKVGGIYVSPFEVEAALALHPAVLEAAVIGVADADD 479 Query 427 ASTLQAFLVATSGATIDGSVMRDLHRGLLNRLSAFKVPHRFAVVDRLPRTPNGKLVRGAL 486 +AF+V G + +L + +RL+ +K P + V+ LP+T GK+ R L Sbjct 480 LIKPKAFVVMRPGQQWHEGMAAELQAFVKSRLAPYKYPRQIECVEELPKTATGKIQRFRL 539 Query 487 RKQ 489 R++ Sbjct 540 RQR 542 >gi|337279878|ref|YP_004619350.1| benzoate-CoA ligase [Ramlibacter tataouinensis TTB310] gi|334730955|gb|AEG93331.1| Candidate benzoate-CoA ligase [Ramlibacter tataouinensis TTB310] Length=524 Score = 241 bits (614), Expect = 4e-61, Method: Compositional matrix adjust. Identities = 173/500 (35%), Positives = 251/500 (51%), Gaps = 28/500 (5%) Query 9 LLAEQASEAGWYDRPAFYAAD---VVTHGQIHDGAARLGEVLRNRGLSSGDRVLLCLPDS 65 LLA A AG + AF A +T+G++ + A R LR+RG+ RVL+ + D+ Sbjct 27 LLARNAGRAG---KAAFIDAASGATLTYGELTERAHRFANGLRSRGIVPETRVLVAMLDT 83 Query 66 PDLVQLLLACLARGVMAFLANPELHRDDHALAARNTEPALVVTSDALRDRFQP------- 118 P+ + L + GV+ N L D R++ + S L F+P Sbjct 84 PEWPVVFLGAILAGVVPVAVNTLLTPRDFEFMLRDSRSQALFVSKPLLPAFEPLLGKLPS 143 Query 119 ---SRVAEAAELMSEAARVAPGGYEP----MGGDALAYATYTSGTTGPPKAAIHRHADPL 171 VA A S A VA G P D + Y+SG+TG PK +H H+ + Sbjct 144 LRHVVVAGAEGEDSVAGWVAAGEATPRVAATCADEACFWLYSSGSTGAPKGTVHLHSHLI 203 Query 172 TFVDAMCRKALRLTPEDTGLCSARMYFAYGLGNSVWFPLATGGSAVINSAPVTPEAAAIL 231 + R L + +D +A+++FAYGLGN++ FPL+ G + V+ A TP + Sbjct 204 QTAELYGRAVLGIREDDVVYSAAKLFFAYGLGNALTFPLSVGATTVLLPARPTPADVFGV 263 Query 232 SARFGPSVLYGVPNFFARVI-DSCSP-DSFRSLRCVVSAGEALELGLAERLMEFFGGIPI 289 +F PS+ YGVP +A ++ D+ P S +LR SAGEAL + R E + G I Sbjct 264 LGKFRPSIFYGVPTLYAGLLADAQRPRRSELNLRICTSAGEALPADIGRRWTEAY-GCEI 322 Query 290 LDGIGSTEVGQTFVSNRVDEWRLGTLGRVLPPYEIRVVAPDGTTAGPGVEGDLWVRGPAI 349 LDGIGSTE+ F+SNR R GT G+ +P YE+R+V DG G G G+L +RGP+ Sbjct 323 LDGIGSTEMLHIFLSNRPGAVRYGTTGQAVPGYELRIVGDDGRECGAGEIGELQIRGPSA 382 Query 350 AKGYW-NRPDSPVANEG-WLDTRDRVCIDSDGWVTYRCRADDTEVIGGVNVDPREVERLI 407 A YW NR + G W + D+ D+DG+ TY R+DD +GG+ V P EVE + Sbjct 383 ALMYWNNRAKTKATFCGDWTKSGDKYTRDADGYYTYGGRSDDMLKVGGIYVSPFEVEASL 442 Query 408 IEDEAVAEAAVVAVRESTGASTLQAFLVATSGATIDGSVMRDLHRGLLNRLSAFKVPHRF 467 + AV EAAV+ V + G +A++V G + DL + N+L+ +K P Sbjct 443 MTHAAVLEAAVIGVADEDGLVKPKAYVVLKPGGQASAA---DLQAHVKNQLAPYKYPRWI 499 Query 468 AVVDRLPRTPNGKLVRGALR 487 V LP+T GK+ R LR Sbjct 500 EFVPELPKTATGKIQRFKLR 519 >gi|85858651|ref|YP_460853.1| 4-hydroxybenzoate--CoA ligase / benzoate--CoA ligase [Syntrophus aciditrophicus SB] gi|85721742|gb|ABC76685.1| 4-hydroxybenzoate--CoA ligase / benzoate--CoA ligase [Syntrophus aciditrophicus SB] Length=524 Score = 240 bits (613), Expect = 6e-61, Method: Compositional matrix adjust. Identities = 148/490 (31%), Positives = 243/490 (50%), Gaps = 37/490 (7%) Query 32 THGQIHDGAARLGEVLRNRGLSSGDRVLLCLPDSPDLVQLLLACLARGVMAFLANPELHR 91 T+ + ++ + R + GDRV++ + D+P + G + +N L Sbjct 38 TYRDMQKMVNKMANMFRKLDIRIGDRVIMLVFDTPWFFSTFWGAVRIGAVPVPSNTMLTS 97 Query 92 DDHALAARNTEPALVVTSDAL--------------RDRFQPSRVAEAA----ELMSEAAR 133 DD+ +++ +V S+ L RD E + ++ ++A+ Sbjct 98 DDYQYYLNDSQARTLVISEKLLPLIKGIKGELRYLRDVIVVDDDGEFSTPYQQMYAQASE 157 Query 134 VAPGGYEPMGGDALAYATYTSGTTGPPKAAIHRHADPLTFVDAMCRKALRLTPEDTGLCS 193 A + D +A+ YTSGTTG PK A+H H+D +A + L +T D + Sbjct 158 EAETAF--TTKDDVAFWQYTSGTTGAPKGAVHSHSDMQYVAEAYGKHVLGMTENDVCYSA 215 Query 194 ARMYFAYGLGNSVWFPLATGGSAVINSAPVTPEAAAILSARFGPSVLYGVPNFFARVI-- 251 AR++FAYG+GN + +PL+ G ++V+N P TPE A L++ + ++ +G+P F +++ Sbjct 216 ARLFFAYGIGNGMVYPLSVGAASVLNPDPPTPERAFRLNSTYKVTLFFGIPTLFGQMLEY 275 Query 252 ------------DSCSPDSFRSLRCVVSAGEALELGLAERLMEFFGGIPILDGIGSTEVG 299 D +P S+R SAGEAL L R E F G+ ILDG GSTE+ Sbjct 276 KVKQEKEAGITPDPKAPHELSSVRACPSAGEALPPDLYHRFKERF-GVEILDGPGSTEML 334 Query 300 QTFVSNRVDEWRLGTLGRVLPPYEIRVVAPDGTTAGPGVEGDLWVRGPAIAKGYWNRPDS 359 ++SN + + + G+ G+V+P YE ++V +G T G G LWV+G + + YW + + Sbjct 335 HIYLSNTLGDVKAGSSGKVVPGYEAKIVGEEGETLPDGEIGTLWVKGDSSLRYYWRKKEK 394 Query 360 PVAN--EGWLDTRDRVCIDSDGWVTYRCRADDTEVIGGVNVDPREVERLIIEDEAVAEAA 417 + GW++T D+ D DG+ RADD +GG+ V P EVE + E AV E A Sbjct 395 TASTIIGGWVNTGDKYYRDKDGYFWPSGRADDMLKVGGIWVSPLEVENCLREHPAVLETA 454 Query 418 VVAVRESTGASTLQAFLVATSGATIDGSVMRDLHRGLLNRLSAFKVPHRFAVVDRLPRTP 477 V+ + +AF+V G + ++L + +L+RL+ FK P +D LP+T Sbjct 455 VIGAEDEKNLVKPKAFVVLKQGFAPSPELEKELKQWVLDRLAKFKYPRWIVFMDELPKTA 514 Query 478 NGKLVRGALR 487 GK+ R LR Sbjct 515 TGKIQRFKLR 524 >gi|339325574|ref|YP_004685267.1| benzoate--CoA ligase BclA [Cupriavidus necator N-1] gi|338165731|gb|AEI76786.1| benzoate--CoA ligase BclA [Cupriavidus necator N-1] Length=551 Score = 239 bits (611), Expect = 9e-61, Method: Compositional matrix adjust. Identities = 162/481 (34%), Positives = 244/481 (51%), Gaps = 23/481 (4%) Query 31 VTHGQIHDGAARLGEVLRNRGLSSGDRVLLCLPDSPDLVQLLLACLARGVMAFLANPELH 90 +T+ ++ A R LR+ G +R+LLC D+ D + L CL GV+ N L Sbjct 63 LTYAELDARARRFAGALRDAGFRQEERLLLCALDTIDFPTVFLGCLLAGVVPVAVNTLLT 122 Query 91 RDDHAL--------AARNTEPALVVTSDALRDR------FQPSRVAEAAELMSEAARVA- 135 DD+A A +EP L V A+ Q + A+ A S A +A Sbjct 123 ADDYAYMLGHSGARAVVVSEPLLPVMKAAIEKSGLAPMVIQAAPHADGAPACSVGAMLAR 182 Query 136 ---PGGYEPMGGDALAYATYTSGTTGPPKAAIHRHADPLTFVDAMCRKALRLTPEDTGLC 192 P G + +A+ Y+SG+TG PK +H H + D R+ L + +D Sbjct 183 TRSPAQTVRSGPEDMAFWLYSSGSTGRPKGTVHTHGNLFHTADLYARQVLGIREDDMVFS 242 Query 193 SARMYFAYGLGNSVWFPLATGGSAVINSAPVTPEAAAILSARFGPSVLYGVPNFFARVID 252 +A+++FAYGLGN++ FP++ G + V+ + TP A P+V GVP FA ++ Sbjct 243 AAKLFFAYGLGNALTFPMSVGATTVLMAERPTPAAVFRRLREQRPTVFCGVPTLFAGMLA 302 Query 253 S--CSPDSFRSLRCVVSAGEALELGLAERLMEFFGGIPILDGIGSTEVGQTFVSNRVDEW 310 + P + +LR SAGEAL + ER + FG ILDGIGSTE+ F+SNR E Sbjct 303 APELPPRAEVALRVCTSAGEALPRDIGERFLAHFG-CDILDGIGSTEMLHIFLSNRPGEV 361 Query 311 RLGTLGRVLPPYEIRVVAPDGTTAGPGVEGDLWVRGPAIAKGYW-NRPDSPVANEG-WLD 368 R GT G+ +P Y ++++ G PG GDL+++GP+ A YW NR S G W Sbjct 362 RYGTTGKPVPGYALKLLDERGEPCAPGEIGDLYIKGPSAALMYWCNRDKSRDTFVGEWTR 421 Query 369 TRDRVCIDSDGWVTYRCRADDTEVIGGVNVDPREVERLIIEDEAVAEAAVVAVRESTGAS 428 + D+ D+DG+ TY R+DD +GG+ V P EVE + + AV EAAV+ V ++ Sbjct 422 SGDKYLCDADGYYTYAGRSDDMLKVGGIYVSPFEVEAALAQHPAVLEAAVIGVTDADELV 481 Query 429 TLQAFLVATSGATIDGSVMRDLHRGLLNRLSAFKVPHRFAVVDRLPRTPNGKLVRGALRK 488 +AF+V G + +L + +RL+ +K P + V LP+T GK+ R LR+ Sbjct 482 KPKAFVVLRPGQQWHDGMAAELQAFIKSRLAPYKYPRQIECVPELPKTATGKIQRFRLRQ 541 Query 489 Q 489 + Sbjct 542 R 542 >gi|261420205|ref|YP_003253887.1| benzoate-CoA ligase family [Geobacillus sp. Y412MC61] gi|297529828|ref|YP_003671103.1| benzoate-CoA ligase family [Geobacillus sp. C56-T3] gi|319767016|ref|YP_004132517.1| benzoate-CoA ligase [Geobacillus sp. Y412MC52] gi|261376662|gb|ACX79405.1| benzoate-CoA ligase family [Geobacillus sp. Y412MC61] gi|297253080|gb|ADI26526.1| benzoate-CoA ligase family [Geobacillus sp. C56-T3] gi|317111882|gb|ADU94374.1| benzoate-CoA ligase family [Geobacillus sp. Y412MC52] Length=525 Score = 239 bits (610), Expect = 1e-60, Method: Compositional matrix adjust. Identities = 152/512 (30%), Positives = 241/512 (48%), Gaps = 30/512 (5%) Query 5 NLAGLLAEQASEAGWYDRPAFYAAD-VVTHGQIHDGAARLGEVLRNRGLSSGDRVLLCLP 63 N AG+ + + G ++ A Y D +++ ++ + + G +LR G DR+++ Sbjct 11 NAAGVFIDHNVQGGLGEKTAIYYRDEQISYRELQEKVNQTGNMLRRLGYRIEDRLVMICH 70 Query 64 DSPDLVQLLLACLARGVMAFLANPELHRDDHALAARNTEPALVVTSDALRDRFQPSR--- 120 D+P+ + + G + N + D+ N+ +V + L +R Q R Sbjct 71 DTPEFIYTFFGAIKIGAVPIPVNTMMQPSDYEYFLNNSRAKGLVIHEDLWERLQLIRERF 130 Query 121 --------VAEAAE-----LMSEAARVAPGGYE----PMGGDALAYATYTSGTTGPPKAA 163 + E A +S +A G E P D A+ ++SG+TG PK Sbjct 131 AFLQDVIVIHENANSSVEGTLSFHRLLACAGRELAAAPTNKDDAAFWLFSSGSTGDPKGI 190 Query 164 IHRHADPLTFVDAMCRKALRLTPEDTGLCSARMYFAYGLGNSVWFPLATGGSAVINSAPV 223 IH D ++ R+ L + D L ++++YFAYGLG ++FPL G S V+ Sbjct 191 IHLQHDMEYALNTYARQVLEINENDRCLSASKLYFAYGLGGGMYFPLGVGASTVLVKERP 250 Query 224 TPEAAAILSARFGPSVLYGVPNFFARVIDSCSPDSFR----SLRCVVSAGEALELGLAER 279 PE + P++ +GVP + +ID R SLR VSAGEAL + Sbjct 251 APEVMFQAIETYKPTIFFGVPTLYGAMIDYVEKTGRRFDVSSLRVCVSAGEALPPSFYYK 310 Query 280 LMEFFGGIPILDGIGSTEVGQTFVSNRVDEWRLGTLGRVLPPYEIRVVAPDGTTAGPGVE 339 + F G+ ILDGIGSTE F+SNR+ + + G+ G+ +P YE++++ G P Sbjct 311 WKQLF-GVDILDGIGSTEALHIFISNRIGDVKPGSSGKEVPGYEVKIIDGQGNELPPNEV 369 Query 340 GDLWVRGPAIAKGYWN---RPDSPVANEGWLDTRDRVCIDSDGWVTYRCRADDTEVIGGV 396 GDL +RG +IA GYWN + E WL D+ D +G+ Y R+DD +GG+ Sbjct 370 GDLIIRGDSIAHGYWNLHEQNKQKFVGE-WLYIGDKYYRDEEGYYWYCGRSDDMLKVGGI 428 Query 397 NVDPREVERLIIEDEAVAEAAVVAVRESTGASTLQAFLVATSGATIDGSVMRDLHRGLLN 456 V P EVE ++ + V EAAVV + G +AF+V G +L + Sbjct 429 WVSPIEVENCLLRHDDVLEAAVVGMENENGLVVPKAFVVLKDGVPRSAEKEEELKQFAKQ 488 Query 457 RLSAFKVPHRFAVVDRLPRTPNGKLVRGALRK 488 L+ +K P ++D LP+T GK+ R LR+ Sbjct 489 HLAHYKYPRIIELIDELPKTATGKIQRFKLRQ 520 >gi|56420526|ref|YP_147844.1| hypothetical protein GK1991 [Geobacillus kaustophilus HTA426] gi|56380368|dbj|BAD76276.1| hypothetical conserved protein [Geobacillus kaustophilus HTA426] Length=525 Score = 239 bits (610), Expect = 1e-60, Method: Compositional matrix adjust. Identities = 149/512 (30%), Positives = 240/512 (47%), Gaps = 30/512 (5%) Query 5 NLAGLLAEQASEAGWYDRPAFYAAD-VVTHGQIHDGAARLGEVLRNRGLSSGDRVLLCLP 63 N AG+ + + G ++ A Y D +++ ++ + + G +LR G DR+++ Sbjct 11 NAAGVFIDHNVQGGLGEKTAIYYRDEQISYRELQEKVNQTGNMLRRLGYRIEDRLVMICH 70 Query 64 DSPDLVQLLLACLARGVMAFLANPELHRDDHALAARNTEPALVVTSDALRDRFQPSR--- 120 D+P+ + + G + N + D+ N+ +V + L +R Q R Sbjct 71 DTPEFIYTFFGAIKIGAVPIPVNTMMQPSDYEYFLNNSRAKGLVIHEDLWERLQLIRERF 130 Query 121 -VAEAAELMSEAARVAPGGY----------------EPMGGDALAYATYTSGTTGPPKAA 163 + ++ E A + G P D A+ ++SG+TG PK Sbjct 131 AFLQDVIVIHENANSSVEGTLSFHRLLACADRELAAAPTNKDDAAFWLFSSGSTGDPKGI 190 Query 164 IHRHADPLTFVDAMCRKALRLTPEDTGLCSARMYFAYGLGNSVWFPLATGGSAVINSAPV 223 IH D ++ R+ L + D L ++++YFAYGLG ++FPL G S V+ Sbjct 191 IHLQHDMEYALNTYARQVLEINENDRCLSASKLYFAYGLGGGMYFPLGVGASTVLVKERP 250 Query 224 TPEAAAILSARFGPSVLYGVPNFFARVID----SCSPDSFRSLRCVVSAGEALELGLAER 279 PE + P++ +GVP + +ID +C SLR VSAGEAL + Sbjct 251 APEVMFQAIETYKPTIFFGVPTLYGAMIDYVEKTCRRFDVSSLRVCVSAGEALPPSFYYK 310 Query 280 LMEFFGGIPILDGIGSTEVGQTFVSNRVDEWRLGTLGRVLPPYEIRVVAPDGTTAGPGVE 339 + F G+ ILDGIGSTE F+SNR+ + + G+ G+ +P YE++++ G P Sbjct 311 WKQLF-GVDILDGIGSTEALHIFISNRIGDVKPGSSGKEVPGYEVKIIDGQGNELPPNEV 369 Query 340 GDLWVRGPAIAKGYWN---RPDSPVANEGWLDTRDRVCIDSDGWVTYRCRADDTEVIGGV 396 GDL +RG +IA GYWN + E WL D+ D +G+ Y R+DD +GG+ Sbjct 370 GDLIIRGDSIAHGYWNLHEQNKQKFVGE-WLYIGDKYYRDEEGYYWYCGRSDDMLKVGGI 428 Query 397 NVDPREVERLIIEDEAVAEAAVVAVRESTGASTLQAFLVATSGATIDGSVMRDLHRGLLN 456 V P EVE ++ + V EAAVV + G +AF+V G +L + Sbjct 429 WVSPIEVENCLLRHDDVLEAAVVGMENENGLVVPKAFVVLKDGVPRSAEKEEELKQFAKQ 488 Query 457 RLSAFKVPHRFAVVDRLPRTPNGKLVRGALRK 488 L+ +K P ++D LP+T GK+ R LR+ Sbjct 489 HLAHYKYPRIIELIDELPKTATGKIQRFKLRQ 520 >gi|300245667|gb|ADJ93891.1| putative benzoate-CoA ligase BzlA [Clostridia bacterium enrichment culture clone BF] Length=524 Score = 238 bits (606), Expect = 4e-60, Method: Compositional matrix adjust. Identities = 162/513 (32%), Positives = 249/513 (49%), Gaps = 35/513 (6%) Query 5 NLAGLLAEQASEAGWYDRPAFYAADV-VTHGQIHDGAARLGEVLRNRGLSSGDRVLLCLP 63 N+ +L + + G ++ A D +T+ ++++ + G +L + G+ RVLL LP Sbjct 13 NMGSILVDTPMQQGLGNKTAIICEDQELTYEEVYNSVNKTGNMLADLGVLREQRVLLLLP 72 Query 64 DSPDLVQLLLACLARGVMAFLANPELHRDDHALAARNTEPA-LVVTSDALR--------- 113 D P+ + ++ + G +A N L D+ ++ A LVV++D L Sbjct 73 DCPEFIFNIIGAMKLGAVAVPLNTLLKPKDYLYYLNDSRAAALVVSTDLLPLVEEILDQV 132 Query 114 ----------DRFQPSRVAEAAELMSEAARVAPGGYEPMGGDALAYATYTSGTTGPPKAA 163 + P + E+ + + D A+ Y+SGTTG PK Sbjct 133 LYLKHVIVVGETTNPKYINYHKEMSKASPELKAA---ETSKDDPAFWLYSSGTTGAPKGT 189 Query 164 IHRHADPLTFVDAMCRKALRLTPEDTGLCSARMYFAYGLGNSVWFPLATGGSAVINSAPV 223 IH H D L + LTP D ++++F+YG NS++ PL +G + ++N P Sbjct 190 IHLHHDMLFAANYFDAGVTNLTPADRIFSVSKLFFSYGNVNSLYLPLLSGATVILN--PE 247 Query 224 TPEAAAILS--ARFGPSVLYGVPNFFARVIDSCSP--DSF--RSLRCVVSAGEALELGLA 277 PEA IL R P+V +GVP ++ ++ + DS+ S+R VSAGE L L Sbjct 248 KPEATRILEIITRHKPTVFFGVPTSYSSMLKAVDQGDDSYDLSSIRVFVSAGENLPPSLW 307 Query 278 ERLMEFFGGIPILDGIGSTEVGQTFVSNRVDEWRLGTLGRVLPPYEIRVVAPDGTTAGPG 337 ++ + FG I DGIGSTEVG +++N + + G+ GR LP YE+++V D PG Sbjct 308 QKWKDRFGS-EICDGIGSTEVGYIYIANSPGQTKPGSSGRALPGYEVKIVDEDNQEVPPG 366 Query 338 VEGDLWVRGPAIAKGYWNRPDSPV-ANEG-WLDTRDRVCIDSDGWVTYRCRADDTEVIGG 395 G L V+G IA GYWN+ V A G W + DR +D DG+ Y R DD +GG Sbjct 367 QPGSLLVKGDGIAAGYWNKHHKTVKAFIGEWYVSGDRFSVDEDGFYWYTGRGDDMVKVGG 426 Query 396 VNVDPREVERLIIEDEAVAEAAVVAVRESTGASTLQAFLVATSGATIDGSVMRDLHRGLL 455 + V P EVE L++E + E AVV + G AF+V G + V DL L Sbjct 427 IWVSPIEVETLLLEHPNIEECAVVGQMDQNGLLKTAAFVVLKDGMEGNEEVTNDLLTHLK 486 Query 456 NRLSAFKVPHRFAVVDRLPRTPNGKLVRGALRK 488 + +A+KVP + LP+T GK+ R LR+ Sbjct 487 AKAAAYKVPRWIYYHNDLPKTATGKIQRFKLRQ 519 >gi|320355252|ref|YP_004196591.1| benzoate-CoA ligase [Desulfobulbus propionicus DSM 2032] gi|320123754|gb|ADW19300.1| benzoate-CoA ligase [Desulfobulbus propionicus DSM 2032] Length=501 Score = 238 bits (606), Expect = 4e-60, Method: Compositional matrix adjust. Identities = 168/481 (35%), Positives = 245/481 (51%), Gaps = 17/481 (3%) Query 21 DRPAFYAA-DVVTHGQIHDGAARLGEVLRNRGLSSGDRVLLCLPDSPDLVQLLLACLARG 79 D+ A+ A V++ Q+ GA +L +G+ GDRVL+ L DSP V L G Sbjct 25 DKTAYLCAGQAVSYRQLAAGAYGFARLLHAKGIGPGDRVLIVLVDSPVFVAAFLGTTLIG 84 Query 80 VMAFLANPELHRDDHALAARNTEP--ALVVTSDALRDRFQPSRV------AEAAELMSEA 131 +A L+ + + ++E ALV S A + F +R AE ++E Sbjct 85 AVAVPVGTALNAETYDFLLSDSEARLALVSPSVAAIEGFPRARTDCLVCGERLAEAVAER 144 Query 132 ARVAPGGYEPMGGDALAYATYTSGTTGPPKAAIHRHADPLTFVDAMCRKALRLTPEDTGL 191 V P +G D LAY YTSG+TG PK HRH D L + + L + +D L Sbjct 145 PSV-PVAAAAVGPDDLAYMLYTSGSTGRPKGVPHRHGDLLAAAERYAVQVLGMGEDDVVL 203 Query 192 CSARMYFAYGLGNSVWFPLATGGSAVINSAPVTPEAAAILSARFGPSVLYGVPNFFARVI 251 ++++YFAYGLGNS+ FPL G +AV++ P+ L AR+ P++ + VP + ++I Sbjct 204 SASKLYFAYGLGNSLAFPLYVGATAVLHPDNPLPDQLLALMARYRPTLFFSVPTVYGQLI 263 Query 252 DSCSPDSFR-SLRCVVSAGEALELGLAERLMEFFGGIPILDGIGSTEVGQTFVSNRVDEW 310 S + D +R VSAGEAL + E + G+ +LDGIGSTE+ F+SNR + Sbjct 264 RSVNEDHLSLPMRLCVSAGEALPAAMVEE-WQRLTGLEVLDGIGSTEMTHIFLSNRPGDL 322 Query 311 RLGTLGRVLPPYEIRVVAPDGTTAGPGVEGDLWVRGPAIAKGYWNRPDSPVAN---EGWL 367 G+ GR +P YE+R+V DG GV G L VRGP A YWNRPD +G++ Sbjct 323 VPGSTGRPVPGYEVRLVDDDGNPVASGVTGHLLVRGPGAAPRYWNRPDKTAETMLADGFI 382 Query 368 DTRDRVCIDSDGWVTYRCRADDTEVIGGVNVDPREVERLIIEDEAVAEAAVVAVRESTGA 427 T D V ++ +G +R R+DD +GG + P +VE ++ V++ AV A R G Sbjct 383 RTGD-VAVEQEGRYWHRGRSDDMLKVGGQWISPLQVEEVLRTHPVVSDCAVAAYRLG-GL 440 Query 428 STLQAFLVATSGATIDGSVMRDLHRGLLNRLSAFKVPHRFAVVDRLPRTPNGKLVRGALR 487 A L+ G + + L L RL + P + VD LPRTP GK+ R L+ Sbjct 441 ERPAAHLILRPGHEPGRPLEKALRAFLAVRLPEYMCPLVYRFVDDLPRTPTGKVQRFKLK 500 Query 488 K 488 + Sbjct 501 Q 501 >gi|189425456|ref|YP_001952633.1| benzoate-CoA ligase [Geobacter lovleyi SZ] gi|189421715|gb|ACD96113.1| benzoate-CoA ligase family [Geobacter lovleyi SZ] Length=501 Score = 237 bits (605), Expect = 5e-60, Method: Compositional matrix adjust. Identities = 160/481 (34%), Positives = 245/481 (51%), Gaps = 34/481 (7%) Query 29 DVVTHGQIHDGAARLGEVLRNRGLSSGDRVLLCLPDSPDLVQLLLACLARGVMAFLANPE 88 + V++ Q+ D A R +L+ G+++GDRVLL LPDSP V L + G +A + Sbjct 34 EAVSYQQLADRACRFATLLQQNGIAAGDRVLLILPDSPVFVAAFLGAVLHGAVAVPVSTA 93 Query 89 LHRDDHALAARNTEPALVVTSDALRDRFQPSRVAEAAELMSEAARVAPGGYEPMGG---- 144 L DD+ +++ ++ S A V AAEL S A E + G Sbjct 94 LTADDYRYILQDSGARFLLYSSA---------VPPAAELASTALTNLVCT-ETLTGWLDH 143 Query 145 -------------DALAYATYTSGTTGPPKAAIHRHADPLTFVDAMCRKALRLTPEDTGL 191 D LA+ YTSG+TG PK HRH D L + L + +D Sbjct 144 CPAARLAAAAPEEDELAFMLYTSGSTGKPKGVPHRHRDLLVAARQYAVQVLGMQQDDLIF 203 Query 192 CSARMYFAYGLGNSVWFPLATGGSAVINSAPVTPEAAAILSARFGPSVLYGVPNFFARVI 251 +++++FAYGLGNS+ FPL TG +A++ P+ L A+ P++ + VP +A++I Sbjct 204 SASKLFFAYGLGNSLAFPLYTGATAILYPGKPLPDELLHLIAQHRPTLFFCVPTVYAQII 263 Query 252 -DSCSPDSFRSLRCVVSAGEALELGLAERLMEFFGGIPILDGIGSTEVGQTFVSNRVDEW 310 + +P+ +R +SAGE L + + + G+ ILDGIG+TE+ F+SN D Sbjct 264 LSTAAPELTLPMRLCISAGEGLPGAVLDE-WQRLTGLAILDGIGTTELTHIFISNYPDRI 322 Query 311 RLGTLGRVLPPYEIRVVAPDGTTAGPGVEGDLWVRGPAIAKGYWNRPDSPVAN---EGWL 367 R G+ G+ +P Y IR+V +G G G L V+G + A YWN P+ A +G++ Sbjct 323 RSGSAGQAVPGYRIRLVDDEGNLVQSGTPGHLQVQGDSTAPCYWNLPEKSAATMLPDGFI 382 Query 368 DTRDRVCIDSDGWVTYRCRADDTEVIGGVNVDPREVERLIIEDEAVAEAAVVAVRESTGA 427 T D V ++ DG+ +R R+DD +GG + P +VE ++ AV + AV A + G Sbjct 383 KTGD-VFLEQDGYYYHRGRSDDMLKVGGQWISPVQVEEVLRSHPAVEDCAVAAC-QIWGL 440 Query 428 STLQAFLVATSGATIDGSVMRDLHRGLLNRLSAFKVPHRFAVVDRLPRTPNGKLVRGALR 487 A L+ G+T D + R+L + RL + VP R+ +VD LPRT GK+ R LR Sbjct 441 MRPAAHLILKPGSTTDPAFERELRSFMAARLPDYMVPVRYHLVDDLPRTATGKVQRFKLR 500 Query 488 K 488 Sbjct 501 S 501 >gi|118579947|ref|YP_901197.1| benzoate-CoA ligase family [Pelobacter propionicus DSM 2379] gi|118502657|gb|ABK99139.1| benzoate-CoA ligase [Pelobacter propionicus DSM 2379] Length=503 Score = 237 bits (604), Expect = 7e-60, Method: Compositional matrix adjust. Identities = 178/518 (35%), Positives = 256/518 (50%), Gaps = 42/518 (8%) Query 1 MRNGNLAGLLAEQASEAGWYDRPAFYAAD-VVTHGQIHDGAARLGEVLRNRGLSSGDRVL 59 M N A +L E+ E D+ AF + +++ ++ + +LR RG+S G+RVL Sbjct 1 MYTDNAAAMLLERNRER-HPDKAAFLCGERSLSYRELERYSRLFALLLRERGISPGERVL 59 Query 60 LCLPDSPDLVQLLLACLARGVMAFLANPELHRDDHALAARNTEPALVVTSDAL------- 112 + LPDS L CL GV A +A L R+ ++ L+VT L Sbjct 60 ILLPDSLAFPVAFLGCLLAGVTAVVAGTALTREQFEHILNDSGSRLLVTDPRLPSPLPPE 119 Query 113 -----------RDRFQPSRVAEAAELMSEAARVAPGGYEPMGGDALAYATYTSGTTGPPK 161 RDRF+P + AA V P D +AY Y+SG+TG PK Sbjct 120 QSRVGLLVCDDRDRFEPPEGHDG----EFAADVPPA-------DRIAYMQYSSGSTGVPK 168 Query 162 AAIHRHADPLTFVDAMCRKALRLTPEDTGLCSARMYFAYGLGNSVWFPLATGGSAVINSA 221 HRH D L D + R+ L L+ +D +++ FAYGL NS+ FPL G +A++ Sbjct 169 GIPHRHRDLLIPCDLVGREILGLSEQDRIFSASKFSFAYGLINSLAFPLFFGATAIL--I 226 Query 222 PVTPEAAAILS--ARFGPSVLYGVPNFFARVIDSCSPDSFR-SLRCVVSAGEALELGLAE 278 P P+AAAIL R PSV + VP ++++I SC D SLR SAGEAL + Sbjct 227 PDKPDAAAILELMERHRPSVFFSVPTVYSQLILSCGSDRLELSLRLCYSAGEALPAAIFH 286 Query 279 RLMEFFGGIPILDGIGSTEVGQTFVSNRVDEWRLGTLGRVLPPYEIRVVAPDGTTAGPGV 338 G+ +LDGIGSTE+ ++SNR R G+ G+ +P Y IR+V DG G Sbjct 287 EWHR-LTGLELLDGIGSTEMSYIYISNRPGRARPGSAGQAVPGYRIRLVDEDGRAVPSGT 345 Query 339 EGDLWVRGPAIAKGYWNRPDSP---VANEGWLDTRDRVCIDSDGWVTYRCRADDTEVIGG 395 G L V+GP YWN PD + +G+L + D + ++ DG+ ++ R DD G Sbjct 346 VGTLLVKGPTSCPCYWNLPDKSGETMLPDGFLRSGD-LFLERDGFYYHQGRNDDMIKAGA 404 Query 396 VNVDPREVERLIIEDEAVAEAAVVAVRESTGASTLQAFLVATSGATIDGSVMRDLHRGLL 455 V P VE ++ +VAE AVVA+ G AF++ + + ++ R L LL Sbjct 405 QLVSPLPVEEALLSHPSVAECAVVAL-SVGGLVRPGAFVIPSPEVQGNPALARRLRAHLL 463 Query 456 NRLSAFKVPHRFAVVDRLPRTPNGKLVRGALRKQSPTK 493 RL + P F V++LPRTP GK+ R LR+ + K Sbjct 464 ERLPEYMCPVSFTFVEQLPRTPTGKIQRFRLREPAQPK 501 >gi|300246001|gb|ADJ94058.1| putative benzoate-CoA ligase BzlA [Clostridia bacterium enrichment culture clone BF] Length=521 Score = 236 bits (601), Expect = 1e-59, Method: Compositional matrix adjust. Identities = 156/506 (31%), Positives = 240/506 (48%), Gaps = 23/506 (4%) Query 5 NLAGLLAEQASEAGWYDRPAFYAADV-VTHGQIHDGAARLGEVLRNRGLSSGDRVLLCLP 63 N+A L ++ + G + A Y D +T+ ++ + G L++ G+ DRVLL + Sbjct 13 NIAVDLVDKNIQRGNGSKVAIYYQDQQLTYEDVYKSVNKTGNALKSLGIGIEDRVLLLVF 72 Query 64 DSPDLVQLLLACLARGVMAFLANPELHRDDHALAARNTEPALVVTSDALRDRFQPSR--- 120 DSP+ V + G + N L D+ ++ + V S+AL + R Sbjct 73 DSPEFVAGFFGAIKIGAVPIPTNTMLKPKDYLYLLNDSRAKVAVVSEALAPLIEEVRSEL 132 Query 121 --------VAEAAELMSEAARVAPGGYEPM-----GGDALAYATYTSGTTGPPKAAIHRH 167 V A A + G + + G D A+ Y+SGTTG PK +H Sbjct 133 LYLRELVVVGNAGPNQLSFAELVAGANDELTAADTGKDDPAFWLYSSGTTGFPKGTVHLQ 192 Query 168 ADPLTFVDAMCRKALRLTPEDTGLCSARMYFAYGLGNSVWFPLATGGSAVINSAPVTPEA 227 D L + + L +T D A+++FAYGLGN ++FP G S V+ P+ Sbjct 193 HDILVACELYGKGILNITENDITFSIAKLFFAYGLGNGLYFPFYVGASTVLYPDRFLPDV 252 Query 228 AAILSARFGPSVLYGVPNFFARVI---DSCSPDSFRSLRCVVSAGEALELGLAERLMEFF 284 L +F P++ +GVP + ++ DS S S+R VSAGEAL + E F Sbjct 253 YFDLVKKFKPTLFFGVPTAYGAMLQAADSISDIDVSSVRYCVSAGEALPKAIFESWKNRF 312 Query 285 GGIPILDGIGSTEVGQTFVSNRVDEWRLGTLGRVLPPYEIRVVAPDGTTAGPGVEGDLWV 344 I ILDGIGSTE+ F+SNR D+ + GT G+ +P YE ++V DG G G L + Sbjct 313 NLI-ILDGIGSTEITHIFISNRPDDVKPGTSGKPVPGYEAKIVDQDGNKLPDGELGTLMI 371 Query 345 RGPAIAKGYWNRPDSPVANEG--WLDTRDRVCIDSDGWVTYRCRADDTEVIGGVNVDPRE 402 +G +IA YWN+ + W+ T D+ +D +G+ TY R DD GG+ V P E Sbjct 372 KGDSIAAYYWNKHEKTKETFYGPWIITGDQYYVDPEGYYTYVGRGDDMIKAGGIWVSPVE 431 Query 403 VERLIIEDEAVAEAAVVAVRESTGASTLQAFLVATSGATIDGSVMRDLHRGLLNRLSAFK 462 VE I+E AV E V+ + +A++V G + ++ +L + R++ +K Sbjct 432 VESTIMEHPAVLECGVIGAVDQDNLIKPKAYVVLKEGFSASEELVTELKAFVKERIALYK 491 Query 463 VPHRFAVVDRLPRTPNGKLVRGALRK 488 P LP+T GK++R LRK Sbjct 492 YPRWIEFTQELPKTATGKIMRFMLRK 517 >gi|90265799|dbj|BAE91925.1| benzoate-CoA ligase [Magnetospirillum sp. TS-6] Length=528 Score = 236 bits (601), Expect = 1e-59, Method: Compositional matrix adjust. Identities = 165/511 (33%), Positives = 252/511 (50%), Gaps = 29/511 (5%) Query 2 RNGNLAGLLAEQASEAGWYDRPAFYAAD-VVTHGQIHDGAARLGEVLRNRGLSSGDRVLL 60 R+ N A ++ + G D+ AF AD T+GQ+ D R G L+ GL +R+ + Sbjct 16 RDYNAATWFIDRHLKDGRADKVAFIDADGSHTYGQLADKVNRAGNALKGLGLHMENRIAM 75 Query 61 CLPDSPDLVQLLLACLARGVMAFLANPELHRDDHALAARNTEPALVVTSDALRDRFQP-- 118 + D+ D + + G++ N L D+ ++ ++V S+ L D+ +P Sbjct 76 IMLDTVDFPAVFWGAVKAGIVPIPLNTLLTTGDYGYMLSDSRARVLVISEELFDKVEPIL 135 Query 119 ------------SRVAEAAELMSEA-ARVAPG-GYEPMGGDALAYATYTSGTTGPPKAAI 164 + A L+S+ A+ P D +A+ Y+SG+TG PK A+ Sbjct 136 PDLPMLEHVVISGKNAHGHTLLSDLLAKAEPKLKTAETTRDDVAFWLYSSGSTGAPKGAV 195 Query 165 HRHAD-PLTFVDAMCRKALRLTPEDTGLCSARMYFAYGLGNSVWFPLATGGSAVINSAPV 223 H D P T V ++ L + +D +A+++FAYGLGN + F L G ++V+ Sbjct 196 HLQRDLPATAVH-YGQQVLGIREDDVTYSAAKLFFAYGLGNGMTFSLHVGATSVLLKDRP 254 Query 224 TPEAAAILSARFGPSVLYGVPNFFARVIDSCSPDSFRS-----LRCVVSAGEALELGLAE 278 TPEA L P++ YGVP + ++ P R LR VSAGEAL + Sbjct 255 TPEAVMKLLKDHQPTIFYGVPTLYGTIL--ADPQYRRETASTRLRACVSAGEALPEDVGR 312 Query 279 RLMEFFGGIPILDGIGSTEVGQTFVSNRVDEWRLGTLGRVLPPYEIRVVAPDGTTAGPGV 338 R E FG ILDG+GSTE+ F+SNR E R GT G+ +P YE+++ + DG G Sbjct 313 RWEERFGA-AILDGLGSTEMLHIFLSNRHGEVRYGTSGKPVPGYELKICSDDGHEVPQGE 371 Query 339 EGDLWVRGPAIAKGYWNRPDSPVANE--GWLDTRDRVCIDSDGWVTYRCRADDTEVIGGV 396 G+L VRGP+ A YWN+ + + W T D+ +D DG+ Y R DD +GG+ Sbjct 372 MGELVVRGPSSATAYWNQREKSLKTFRGEWTHTGDKYYVDDDGYYRYAGRGDDMLKVGGI 431 Query 397 NVDPREVERLIIEDEAVAEAAVVAVRESTGASTLQAFLVATSGATIDGSVMRDLHRGLLN 456 V P EVE +I + V EAAVV ++ G +AF+V G T + +L + + Sbjct 432 WVSPFEVEAALISHDKVLEAAVVGETDAEGLVKPKAFVVLAPGETGSEVLKEELQAYVKS 491 Query 457 RLSAFKVPHRFAVVDRLPRTPNGKLVRGALR 487 +L+ +K P V+ LP+T GK+ R LR Sbjct 492 KLAPYKYPRWVEFVEALPKTATGKIQRFKLR 522 >gi|83311968|ref|YP_422232.1| Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase [Magnetospirillum magneticum AMB-1] gi|82946809|dbj|BAE51673.1| Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase [Magnetospirillum magneticum AMB-1] Length=528 Score = 236 bits (601), Expect = 1e-59, Method: Compositional matrix adjust. Identities = 166/515 (33%), Positives = 251/515 (49%), Gaps = 37/515 (7%) Query 2 RNGNLAGLLAEQASEAGWYDRPAFYAAD-VVTHGQIHDGAARLGEVLRNRGLSSGDRVLL 60 R+ N A ++ + G + AF AD T+ Q+ + R G L++ GL +R+ + Sbjct 16 RDYNAATWFIDRHIKDGRSAKVAFIDADGSHTYAQLGEKVNRAGNALKSLGLHMENRIAM 75 Query 61 CLPDSPDLVQLLLACLARGVMAFLANPELHRDDHALAARNTEPALVVTSDALRDRFQP-- 118 + D+ D + + G++ N L D+ ++ ++V S+ L D+ +P Sbjct 76 IMLDTVDFPSVFWGAIKAGIVPIPLNTLLTTGDYGYMLSDSRARVLVISEELFDKVEPIL 135 Query 119 ------------SRVAEAAELMSEAARVAPGGYEP------MGGDALAYATYTSGTTGPP 160 + A L+S+ A EP D +A+ Y+SG+TG P Sbjct 136 PDLPLLEHVVISGKNAHGHTLLSDMMAAA----EPKLKTAETTRDDVAFWLYSSGSTGAP 191 Query 161 KAAIHRHAD-PLTFVDAMCRKALRLTPEDTGLCSARMYFAYGLGNSVWFPLATGGSAVIN 219 K A+H D P T V ++ L +T +D +A+++FAYGLGN + F L G ++V+ Sbjct 192 KGAVHLQRDLPATAVH-YGQQVLGITEDDVTFSAAKLFFAYGLGNGMTFSLHVGATSVLL 250 Query 220 SAPVTPEAAAILSARFGPSVLYGVPNFFARVIDSCSPDSFRS-----LRCVVSAGEALEL 274 TPEA + P++ YGVP + ++ P R LR VSAGEAL Sbjct 251 KDRPTPEAVMKILKDHQPTIFYGVPTLYGTIL--ADPQYRRETASTRLRACVSAGEALPE 308 Query 275 GLAERLMEFFGGIPILDGIGSTEVGQTFVSNRVDEWRLGTLGRVLPPYEIRVVAPDGTTA 334 + R E FG ILDG+GSTE+ F+SNR E R GT G+ +P Y++++VA DG Sbjct 309 DVGRRWEERFGA-AILDGLGSTEMLHIFLSNRHGEVRYGTSGKAVPGYDLKIVADDGHEL 367 Query 335 GPGVEGDLWVRGPAIAKGYWNRPDSPVANE--GWLDTRDRVCIDSDGWVTYRCRADDTEV 392 G G+L VRGP+ A YWN+ + + W T D+ +D DG+ Y R DD Sbjct 368 PQGEMGELVVRGPSSATAYWNQREKSLKTFRGEWTHTGDKYFVDDDGYYRYAGRGDDMLK 427 Query 393 IGGVNVDPREVERLIIEDEAVAEAAVVAVRESTGASTLQAFLVATSGATIDGSVMRDLHR 452 +GG+ V P EVE +I E V EAAVV +S G +AF+V G T + L Sbjct 428 VGGIWVSPFEVEAALISHEMVLEAAVVGEADSEGLVKPKAFVVLAPGETGSEVLKEQLQA 487 Query 453 GLLNRLSAFKVPHRFAVVDRLPRTPNGKLVRGALR 487 + +L+ +K P V+ LP+T GK+ R LR Sbjct 488 YVKAKLAPYKYPRWIEFVEALPKTATGKIQRFKLR 522 >gi|221069666|ref|ZP_03545771.1| benzoate-CoA ligase family [Comamonas testosteroni KF-1] gi|220714689|gb|EED70057.1| benzoate-CoA ligase family [Comamonas testosteroni KF-1] Length=520 Score = 235 bits (600), Expect = 2e-59, Method: Compositional matrix adjust. Identities = 161/492 (33%), Positives = 246/492 (50%), Gaps = 32/492 (6%) Query 30 VVTHGQIHDGAARLGEVLRNRGLSSGDRVLLCLPDSPDLVQLLLACLARGVMAFLANPEL 89 +++ Q+ + A RL L G+ +RVLL + D + V L + GV+ N L Sbjct 33 TLSYAQLQEQARRLAHGLLAAGIHREERVLLVMHDMREWVISFLGAMYAGVVPVAVNTLL 92 Query 90 HRDDHALAARNTEPALVVTSDALRDRFQPSRVAEAAELMS-------EAARVAPGGYEPM 142 D+A + ++T+ AL Q + E+ +A+ P +E + Sbjct 93 TAADYAYMLEHCRAQAILTNGALVPVVQQALEQAHHEVNHIWVARPEDASPGLPPAFEAL 152 Query 143 G----------------GDALAYATYTSGTTGPPKAAIHRHADPLTFVDAMCRKALRLTP 186 GD + Y+SG+TG PK A+H HA+P + + L L Sbjct 153 QPWLQQQTPLAHAARTMGDDPGFWLYSSGSTGKPKGAVHTHANPYWTAELYGKPVLGLNE 212 Query 187 EDTGLCSARMYFAYGLGNSVWFPLATGGSAVINSAPVTPEAAAILSARFGPSVLYGVPNF 246 D +A++YFAYGLGN++ FPL+ G S V+ + TPEA P+V +G P Sbjct 213 NDVCFSAAKLYFAYGLGNALTFPLSVGASVVLMAERPTPEATFRRWTEHRPTVFFGAPTG 272 Query 247 FARVIDSCS-PDSFR-SLRCVVSAGEALELGLAERLMEFFGGIPILDGIGSTEVGQTFVS 304 FA ++ + P R SLR SAGEAL +A+R FG I+DGIGSTE+ F+S Sbjct 273 FAGMLAHPALPARERVSLRMCSSAGEALPAEIAQRFKNHFGA-DIVDGIGSTEMLHIFLS 331 Query 305 NRVDEWRLGTLGRVLPPYEIRVVAPDGTTAGPGVEGDLWVRGPAIAKGYW-NRPDSPVAN 363 NR D+ R G+ G+ +P Y + + DG G GDL+++GP+ A YW NR + Sbjct 332 NRPDDIRYGSTGKPVPGYAVELRGEDGQPVADGEIGDLYIKGPSAALMYWANRDKTRDTF 391 Query 364 EG-WLDTRDRVCIDSDGWVTYRCRADDTEVIGGVNVDPREVERLIIEDEAVAEAAVVAVR 422 +G WL + D+ D++G+ TY R+DD + G+ V P EVE + + AV EAAV+ V Sbjct 392 QGAWLKSGDKYVRDAEGYYTYAGRSDDMLKVSGIYVSPFEVESTLQQHPAVLEAAVIGVT 451 Query 423 ESTGASTLQAFLVATSGATIDGSVMRDLHRGLLNRLSAFKVPHRFAVVDRLPRTPNGKLV 482 + G + ++++V G + ++ + NRL+A+K P VD LP+T GK+ Sbjct 452 DEQGLTKTKSYVVCKPGQSASEDELKAF---VKNRLAAYKYPRFIEFVDELPKTATGKIQ 508 Query 483 RGALRKQSPTKP 494 R LR+ TKP Sbjct 509 RFRLRELD-TKP 519 >gi|56478449|ref|YP_160038.1| benzoate-CoA ligase [Aromatoleum aromaticum EbN1] gi|56314492|emb|CAI09137.1| Benzoate-CoA ligase [Aromatoleum aromaticum EbN1] Length=533 Score = 235 bits (600), Expect = 2e-59, Method: Compositional matrix adjust. Identities = 165/486 (34%), Positives = 236/486 (49%), Gaps = 32/486 (6%) Query 32 THGQIHDGAARLGEVLRNRGLSSGDRVLLCLPDSPDLVQLLLACLARGVMAFLANPELHR 91 T+ Q+ + R L G+ +RV+LCL D+ D L C+ GV+ N L Sbjct 51 TYAQLAERVDRFAHALGEMGVRMEERVVLCLLDTVDFPTAFLGCIKAGVVPVPINTLLTA 110 Query 92 DDHALAARNTEPALVVTSDALRDRFQPSRVAEAAELMSE--------------------- 130 D++ R++ +V S L F + E + + Sbjct 111 SDYSYMLRDSRARALVVSSLLLPAF--ANAIEQSPFVKNVVVSGGDAGVRGSHLDFADLL 168 Query 131 AARVAPGGYEPMGGDALAYATYTSGTTGPPKAAIHRHADPLTFVDAMCRKALRLTPEDTG 190 AA P P D + Y+SG+TG PK +H H+ +T + R L + D Sbjct 169 AAPRPPFEAAPTCADDPCFWLYSSGSTGAPKGTVHLHSSLITTFELYARPILDVQESDVV 228 Query 191 LCSARMYFAYGLGNSVWFPLATGGSAVINSAPVTPEAAAILSARFGPSVLYGVPNFFARV 250 +A+++FAYGLGN + FPLA G +AV+ S TP + + + R P+V GVP +A + Sbjct 229 FSAAKLFFAYGLGNGLTFPLAAGATAVLMSERPTPASVSRVLRRHQPTVYCGVPTLYASM 288 Query 251 IDSCSPD----SFRSLRCVVSAGEALELGLAERLMEFFGGIPILDGIGSTEVGQTFVSNR 306 + SP+ + S+R SAGEAL + +R E F G+ ILDG+GSTE+ F+SNR Sbjct 289 L--ASPELPGRAEVSIRRCASAGEALPAEVGKRWTEHF-GVEILDGLGSTEMLHIFLSNR 345 Query 307 VDEWRLGTLGRVLPPYEIRVVAPDGTTAGPGVEGDLWVRGPAIAKGYW-NRPDSPVANEG 365 E R GT G+ +P YE+R++ DG PG G+L VRGP A YW NR S G Sbjct 346 HGEARYGTSGKPVPGYELRLIGDDGEEVAPGEPGELQVRGPTSAALYWNNRSKSRDTFMG 405 Query 366 -WLDTRDRVCIDSDGWVTYRCRADDTEVIGGVNVDPREVERLIIEDEAVAEAAVVAVRES 424 W + D+ D+DG Y R DD +GG+ V P EVE +I EAV EAAVV + Sbjct 406 QWTRSGDKYSQDADGNFAYAGRNDDMLKVGGIYVSPIEVESALITHEAVLEAAVVGKADV 465 Query 425 TGASTLQAFLVATSGATIDGSVMRDLHRGLLNRLSAFKVPHRFAVVDRLPRTPNGKLVRG 484 G AF+V G + +L + ++L+ +K P VD LP+T GK+ R Sbjct 466 DGLIKPLAFVVLKPGLRPSPGLGDELKLHVKSKLAPYKYPRWLEFVDELPKTATGKIQRF 525 Query 485 ALRKQS 490 LR S Sbjct 526 KLRASS 531 Lambda K H 0.318 0.135 0.403 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 1663464760236 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40