BLAST Search Results


BLASTP 2.2.25+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.



Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
           15,229,318 sequences; 5,219,829,388 total letters



Query= Rv2970A

Length=56
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

gi|31794147|ref|NP_856640.1|  hypothetical protein Mb2995 [Mycoba...   115    3e-24
gi|118471723|ref|YP_886748.1|  2,5-diketo-D-gluconic acid reducta...  66.6    1e-09
gi|119868022|ref|YP_937974.1|  2,5-didehydrogluconate reductase [...  63.2    1e-08
gi|126434507|ref|YP_001070198.1|  2,5-didehydrogluconate reductas...  63.2    1e-08
gi|108798907|ref|YP_639104.1|  aldo/keto reductase [Mycobacterium...  62.8    2e-08
gi|312138484|ref|YP_004005820.1|  aldo/keto reductase [Rhodococcu...  62.0    3e-08
gi|325676132|ref|ZP_08155813.1|  2,5-diketo-D-gluconate reductase...  62.0    3e-08
gi|226364498|ref|YP_002782280.1|  2,5-diketo-D-gluconate reductas...  60.8    7e-08
gi|169628619|ref|YP_001702268.1|  oxidoreductase [Mycobacterium a...  60.1    1e-07
gi|111021991|ref|YP_704963.1|  reductase [Rhodococcus jostii RHA1...  59.7    1e-07
gi|297560359|ref|YP_003679333.1|  2,5-didehydrogluconate reductas...  59.7    2e-07
gi|14587006|gb|AAK70425.1|AF385141_2  2,5-diketo-D-gluconic acid ...  59.3    2e-07
gi|14587011|gb|AAK70428.1|AF385143_1  2,5-diketo-D-gluconic acid ...  59.3    2e-07
gi|340772259|gb|EGR94765.1|  2,5-diketo-D-gluconic acid reductase...  59.3    2e-07
gi|163839877|ref|YP_001624282.1|  2,5-diketo-D-gluconic acid redu...  59.3    2e-07
gi|333991314|ref|YP_004523928.1|  oxidoreductase [Mycobacterium s...  59.3    2e-07
gi|14587002|gb|AAK70423.1|AF385140_3  2,5-diketo-D-gluconic acid ...  58.9    2e-07
gi|50843567|ref|YP_056794.1|  2,5-diketo-D-gluconic acid reductas...  58.9    3e-07
gi|14587009|gb|AAK70427.1|AF385142_1  2,5-diketo-D-gluconic acid ...  58.5    3e-07
gi|309813180|ref|ZP_07706902.1|  2,5-diketo-D-gluconic acid reduc...  58.5    3e-07
gi|226304268|ref|YP_002764226.1|  morphine 6-dehydrogenase [Rhodo...  58.2    4e-07
gi|297161631|gb|ADI11343.1|  putative oxidoreductase [Streptomyce...  58.2    4e-07
gi|329940292|ref|ZP_08289573.1|  oxidoreductase [Streptomyces gri...  58.2    5e-07
gi|289427854|ref|ZP_06429558.1|  oxidoreductase, aldo/keto reduct...  57.4    6e-07
gi|269125831|ref|YP_003299201.1|  2,5-didehydrogluconate reductas...  57.4    7e-07
gi|229488912|ref|ZP_04382778.1|  2,5-diketo-D-gluconic acid reduc...  57.4    8e-07
gi|291299234|ref|YP_003510512.1|  2,5-didehydrogluconate reductas...  57.0    8e-07
gi|54022639|ref|YP_116881.1|  putative oxidoreductase [Nocardia f...  57.0    9e-07
gi|284041555|ref|YP_003391895.1|  aldo/keto reductase [Conexibact...  57.0    9e-07
gi|333918533|ref|YP_004492114.1|  putative 2,5-diketo-D-gluconate...  56.6    1e-06
gi|226308044|ref|YP_002768004.1|  2,5-diketo-D-gluconate reductas...  56.6    1e-06
gi|297584691|ref|YP_003700471.1|  2,5-didehydrogluconate reductas...  56.6    1e-06
gi|302524709|ref|ZP_07277051.1|  oxidoreductase [Streptomyces sp....  56.6    1e-06
gi|153010336|ref|YP_001371550.1|  2,5-didehydrogluconate reductas...  56.6    1e-06
gi|239833526|ref|ZP_04681854.1|  2,5-diketo-D-gluconic acid reduc...  56.6    1e-06
gi|331699333|ref|YP_004335572.1|  2,5-didehydrogluconate reductas...  56.2    1e-06
gi|289426055|ref|ZP_06427802.1|  oxidoreductase, aldo/keto reduct...  56.2    1e-06
gi|296138592|ref|YP_003645835.1|  aldo/keto reductase [Tsukamurel...  56.2    1e-06
gi|317506058|ref|ZP_07963886.1|  aldo/keto reductase [Segniliparu...  56.2    2e-06
gi|302566267|pdb|3O0K|A  Chain A, Crystal Structure Of AldoKETO R...  56.2    2e-06
gi|294853201|ref|ZP_06793873.1|  aldo/keto reductase [Brucella sp...  56.2    2e-06
gi|297562467|ref|YP_003681441.1|  2,5-didehydrogluconate reductas...  55.8    2e-06
gi|328880228|emb|CCA53467.1|  oxidoreductase of aldo or keto redu...  55.8    2e-06
gi|313836271|gb|EFS73985.1|  oxidoreductase, aldo/keto reductase ...  55.8    2e-06
gi|325001278|ref|ZP_08122390.1|  2,5-diketo-D-gluconic acid reduc...  55.8    2e-06
gi|306840986|ref|ZP_07473727.1|  aldo/keto reductase family oxido...  55.8    2e-06
gi|306845501|ref|ZP_07478070.1|  aldo/keto reductase family oxido...  55.8    2e-06
gi|320006896|gb|ADW01746.1|  Methylglyoxal reductase (NADPH-depen...  55.8    2e-06
gi|62317130|ref|YP_222983.1|  aldo/keto reductase family oxidored...  55.8    2e-06
gi|23499945|ref|NP_699385.1|  aldo/keto reductase family oxidored...  55.8    2e-06


>gi|31794147|ref|NP_856640.1| hypothetical protein Mb2995 [Mycobacterium bovis AF2122/97]
 gi|57117040|ref|YP_177681.1| hypothetical protein Rv2970A [Mycobacterium tuberculosis H37Rv]
 gi|121638852|ref|YP_979076.1| hypothetical protein BCG_2992 [Mycobacterium bovis BCG str. Pasteur 
1173P2]
 29 more sequence titles
 gi|148662819|ref|YP_001284342.1| hypothetical protein MRA_2998A [Mycobacterium tuberculosis H37Ra]
 gi|167970008|ref|ZP_02552285.1| hypothetical protein MtubH3_19043 [Mycobacterium tuberculosis 
H37Ra]
 gi|224991344|ref|YP_002646033.1| hypothetical protein JTY_2987 [Mycobacterium bovis BCG str. Tokyo 
172]
 gi|254552048|ref|ZP_05142495.1| hypothetical protein Mtube_16582 [Mycobacterium tuberculosis 
'98-R604 INH-RIF-EM']
 gi|289444534|ref|ZP_06434278.1| conserved hypothetical protein [Mycobacterium tuberculosis T46]
 gi|289448642|ref|ZP_06438386.1| conserved hypothetical protein [Mycobacterium tuberculosis CPHL_A]
 gi|289571168|ref|ZP_06451395.1| conserved hypothetical protein [Mycobacterium tuberculosis T17]
 gi|289746769|ref|ZP_06506147.1| conserved hypothetical protein [Mycobacterium tuberculosis 02_1987]
 gi|289751647|ref|ZP_06511025.1| conserved hypothetical protein [Mycobacterium tuberculosis T92]
 gi|294993943|ref|ZP_06799634.1| hypothetical protein Mtub2_05358 [Mycobacterium tuberculosis 
210]
 gi|297635594|ref|ZP_06953374.1| hypothetical protein MtubK4_15802 [Mycobacterium tuberculosis 
KZN 4207]
 gi|297732592|ref|ZP_06961710.1| hypothetical protein MtubKR_15962 [Mycobacterium tuberculosis 
KZN R506]
 gi|313659924|ref|ZP_07816804.1| hypothetical protein MtubKV_15962 [Mycobacterium tuberculosis 
KZN V2475]
 gi|339632977|ref|YP_004724619.1| hypothetical protein MAF_29760 [Mycobacterium africanum GM041182]
 gi|340627960|ref|YP_004746412.1| hypothetical protein MCAN_29931 [Mycobacterium canettii CIPT 
140010059]
 gi|31619742|emb|CAD96682.1| CONSERVED HYPOTHETICAL PROTEIN [Mycobacterium bovis AF2122/97]
 gi|41352769|emb|CAE55533.1| CONSERVED HYPOTHETICAL PROTEIN [Mycobacterium tuberculosis H37Rv]
 gi|121494500|emb|CAL72981.1| Conserved hypothetical protein [Mycobacterium bovis BCG str. 
Pasteur 1173P2]
 gi|148506971|gb|ABQ74780.1| hypothetical protein MRA_2998A [Mycobacterium tuberculosis H37Ra]
 gi|224774459|dbj|BAH27265.1| hypothetical protein JTY_2987 [Mycobacterium bovis BCG str. Tokyo 
172]
 gi|289417453|gb|EFD14693.1| conserved hypothetical protein [Mycobacterium tuberculosis T46]
 gi|289421600|gb|EFD18801.1| conserved hypothetical protein [Mycobacterium tuberculosis CPHL_A]
 gi|289544922|gb|EFD48570.1| conserved hypothetical protein [Mycobacterium tuberculosis T17]
 gi|289687297|gb|EFD54785.1| conserved hypothetical protein [Mycobacterium tuberculosis 02_1987]
 gi|289692234|gb|EFD59663.1| conserved hypothetical protein [Mycobacterium tuberculosis T92]
 gi|339332333|emb|CCC28046.1| conserved hypothetical protein [Mycobacterium africanum GM041182]
 gi|340006150|emb|CCC45324.1| conserved hypothetical protein [Mycobacterium canettii CIPT 140010059]
 gi|341602891|emb|CCC65569.1| conserved hypothetical protein [Mycobacterium bovis BCG str. 
Moreau RDJ]
 gi|344220804|gb|AEN01435.1| hypothetical protein MTCTRI2_3029 [Mycobacterium tuberculosis 
CTRI-2]
Length=56

 Score =  115 bits (287),  Expect = 3e-24, Method: Compositional matrix adjust.
 Identities = 55/56 (99%), Positives = 56/56 (100%), Gaps = 0/56 (0%)

Query  1   VLIRWHIQLGNIVIPKSVNPMRIASNFDAFDFPRSMTEPGLVRIRKPSISQAGEMT  56
           +LIRWHIQLGNIVIPKSVNPMRIASNFDAFDFPRSMTEPGLVRIRKPSISQAGEMT
Sbjct  1   MLIRWHIQLGNIVIPKSVNPMRIASNFDAFDFPRSMTEPGLVRIRKPSISQAGEMT  56


>gi|118471723|ref|YP_886748.1| 2,5-diketo-D-gluconic acid reductase A [Mycobacterium smegmatis 
str. MC2 155]
 gi|254801320|sp|A0QV10.1|Y2408_MYCS2 RecName: Full=Uncharacterized oxidoreductase MSMEG_2408
 gi|118173010|gb|ABK73906.1| 2,5-diketo-D-gluconic acid reductase A [Mycobacterium smegmatis 
str. MC2 155]
Length=275

 Score = 66.6 bits (161),  Expect = 1e-09, Method: Compositional matrix adjust.
 Identities = 31/35 (89%), Positives = 31/35 (89%), Gaps = 0/35 (0%)

Query  1    VLIRWHIQLGNIVIPKSVNPMRIASNFDAFDFPRS  35
            VLIRWHIQLGNIVIPKSVNP RIASNFD FDF  S
Sbjct  214  VLIRWHIQLGNIVIPKSVNPERIASNFDVFDFELS  248


>gi|119868022|ref|YP_937974.1| 2,5-didehydrogluconate reductase [Mycobacterium sp. KMS]
 gi|254801515|sp|A1UEC6.1|Y1985_MYCSK RecName: Full=Uncharacterized oxidoreductase Mkms_1985
 gi|119694111|gb|ABL91184.1| 2,5-didehydrogluconate reductase [Mycobacterium sp. KMS]
Length=276

 Score = 63.2 bits (152),  Expect = 1e-08, Method: Compositional matrix adjust.
 Identities = 28/35 (80%), Positives = 29/35 (83%), Gaps = 0/35 (0%)

Query  1    VLIRWHIQLGNIVIPKSVNPMRIASNFDAFDFPRS  35
             LIRWH+QLGNIVIPKSVNP RI SNFD FDF  S
Sbjct  215  ALIRWHMQLGNIVIPKSVNPQRIESNFDVFDFELS  249


>gi|126434507|ref|YP_001070198.1| 2,5-didehydrogluconate reductase [Mycobacterium sp. JLS]
 gi|254800656|sp|A3PXT0.1|Y1919_MYCSJ RecName: Full=Uncharacterized oxidoreductase Mjls_1919
 gi|126234307|gb|ABN97707.1| 2,5-didehydrogluconate reductase [Mycobacterium sp. JLS]
Length=276

 Score = 63.2 bits (152),  Expect = 1e-08, Method: Compositional matrix adjust.
 Identities = 28/35 (80%), Positives = 29/35 (83%), Gaps = 0/35 (0%)

Query  1    VLIRWHIQLGNIVIPKSVNPMRIASNFDAFDFPRS  35
             LIRWH+QLGNIVIPKSVNP RI SNFD FDF  S
Sbjct  215  ALIRWHMQLGNIVIPKSVNPQRIESNFDVFDFELS  249


>gi|108798907|ref|YP_639104.1| aldo/keto reductase [Mycobacterium sp. MCS]
 gi|108769326|gb|ABG08048.1| aldo/keto reductase [Mycobacterium sp. MCS]
Length=207

 Score = 62.8 bits (151),  Expect = 2e-08, Method: Compositional matrix adjust.
 Identities = 28/35 (80%), Positives = 29/35 (83%), Gaps = 0/35 (0%)

Query  1    VLIRWHIQLGNIVIPKSVNPMRIASNFDAFDFPRS  35
             LIRWH+QLGNIVIPKSVNP RI SNFD FDF  S
Sbjct  146  ALIRWHMQLGNIVIPKSVNPQRIESNFDVFDFELS  180


>gi|312138484|ref|YP_004005820.1| aldo/keto reductase [Rhodococcus equi 103S]
 gi|311887823|emb|CBH47135.1| aldo/keto reductase [Rhodococcus equi 103S]
Length=278

 Score = 62.0 bits (149),  Expect = 3e-08, Method: Compositional matrix adjust.
 Identities = 26/32 (82%), Positives = 29/32 (91%), Gaps = 0/32 (0%)

Query  1    VLIRWHIQLGNIVIPKSVNPMRIASNFDAFDF  32
            V++RWHIQLGN+VIPKSV P RIASNFD FDF
Sbjct  219  VILRWHIQLGNVVIPKSVTPERIASNFDVFDF  250


>gi|325676132|ref|ZP_08155813.1| 2,5-diketo-D-gluconate reductase [Rhodococcus equi ATCC 33707]
 gi|325553042|gb|EGD22723.1| 2,5-diketo-D-gluconate reductase [Rhodococcus equi ATCC 33707]
Length=278

 Score = 62.0 bits (149),  Expect = 3e-08, Method: Compositional matrix adjust.
 Identities = 26/32 (82%), Positives = 29/32 (91%), Gaps = 0/32 (0%)

Query  1    VLIRWHIQLGNIVIPKSVNPMRIASNFDAFDF  32
            V++RWHIQLGN+VIPKSV P RIASNFD FDF
Sbjct  219  VILRWHIQLGNVVIPKSVTPERIASNFDVFDF  250


>gi|226364498|ref|YP_002782280.1| 2,5-diketo-D-gluconate reductase [Rhodococcus opacus B4]
 gi|226242987|dbj|BAH53335.1| putative 2,5-diketo-D-gluconate reductase [Rhodococcus opacus 
B4]
Length=282

 Score = 60.8 bits (146),  Expect = 7e-08, Method: Composition-based stats.
 Identities = 24/32 (75%), Positives = 29/32 (91%), Gaps = 0/32 (0%)

Query  1    VLIRWHIQLGNIVIPKSVNPMRIASNFDAFDF  32
            V+IRWH+Q+GN+VIPKSV P RIA+NFD FDF
Sbjct  222  VIIRWHLQIGNVVIPKSVTPERIAANFDVFDF  253


>gi|169628619|ref|YP_001702268.1| oxidoreductase [Mycobacterium abscessus ATCC 19977]
 gi|169240586|emb|CAM61614.1| Probable oxidoreductase [Mycobacterium abscessus]
Length=271

 Score = 60.1 bits (144),  Expect = 1e-07, Method: Composition-based stats.
 Identities = 25/38 (66%), Positives = 30/38 (79%), Gaps = 0/38 (0%)

Query  1    VLIRWHIQLGNIVIPKSVNPMRIASNFDAFDFPRSMTE  38
            V++RWH+QLGN+VIPKSV P RIA+NFD F F  S  E
Sbjct  210  VILRWHLQLGNVVIPKSVTPARIAANFDVFGFELSTDE  247


>gi|111021991|ref|YP_704963.1| reductase [Rhodococcus jostii RHA1]
 gi|110821521|gb|ABG96805.1| reductase [Rhodococcus jostii RHA1]
Length=315

 Score = 59.7 bits (143),  Expect = 1e-07, Method: Compositional matrix adjust.
 Identities = 24/32 (75%), Positives = 29/32 (91%), Gaps = 0/32 (0%)

Query  1    VLIRWHIQLGNIVIPKSVNPMRIASNFDAFDF  32
            V+IRWH+Q+GN+VIPKSV P RIA+NFD FDF
Sbjct  255  VIIRWHLQIGNVVIPKSVTPERIAANFDVFDF  286


>gi|297560359|ref|YP_003679333.1| 2,5-didehydrogluconate reductase [Nocardiopsis dassonvillei subsp. 
dassonvillei DSM 43111]
 gi|296844807|gb|ADH66827.1| 2,5-didehydrogluconate reductase [Nocardiopsis dassonvillei subsp. 
dassonvillei DSM 43111]
Length=281

 Score = 59.7 bits (143),  Expect = 2e-07, Method: Composition-based stats.
 Identities = 27/38 (72%), Positives = 29/38 (77%), Gaps = 0/38 (0%)

Query  1    VLIRWHIQLGNIVIPKSVNPMRIASNFDAFDFPRSMTE  38
            VL+RWHIQLGN+VIPKSV P RI SNF  FDF  S  E
Sbjct  221  VLLRWHIQLGNVVIPKSVTPERIRSNFQVFDFELSRAE  258


>gi|14587006|gb|AAK70425.1|AF385141_2 2,5-diketo-D-gluconic acid reductase [uncultured bacterium]
Length=273

 Score = 59.3 bits (142),  Expect = 2e-07, Method: Composition-based stats.
 Identities = 25/42 (60%), Positives = 32/42 (77%), Gaps = 0/42 (0%)

Query  1    VLIRWHIQLGNIVIPKSVNPMRIASNFDAFDFPRSMTEPGLV  42
            V+IRWH+QL N+VIPKS NP R+A NFD FDF  S  + G++
Sbjct  215  VIIRWHLQLQNLVIPKSSNPDRLAENFDVFDFELSQHQMGII  256


>gi|14587011|gb|AAK70428.1|AF385143_1 2,5-diketo-D-gluconic acid reductase [uncultured bacterium]
Length=273

 Score = 59.3 bits (142),  Expect = 2e-07, Method: Composition-based stats.
 Identities = 25/42 (60%), Positives = 32/42 (77%), Gaps = 0/42 (0%)

Query  1    VLIRWHIQLGNIVIPKSVNPMRIASNFDAFDFPRSMTEPGLV  42
            V+IRWH+QL N+VIPKS NP R+A NFD FDF  S  + G++
Sbjct  215  VIIRWHLQLQNLVIPKSSNPDRLAENFDVFDFELSQHQMGII  256


>gi|340772259|gb|EGR94765.1| 2,5-diketo-D-gluconic acid reductase A [Propionibacterium acnes 
SK182B-JCVI]
Length=273

 Score = 59.3 bits (142),  Expect = 2e-07, Method: Composition-based stats.
 Identities = 24/35 (69%), Positives = 28/35 (80%), Gaps = 0/35 (0%)

Query  1    VLIRWHIQLGNIVIPKSVNPMRIASNFDAFDFPRS  35
            V+IRWH+Q+GN+V PKSV P RIA NFD FDF  S
Sbjct  214  VVIRWHLQIGNVVFPKSVTPSRIAENFDVFDFELS  248


>gi|163839877|ref|YP_001624282.1| 2,5-diketo-D-gluconic acid reductase [Renibacterium salmoninarum 
ATCC 33209]
 gi|162953353|gb|ABY22868.1| 2,5-diketo-D-gluconic acid reductase [Renibacterium salmoninarum 
ATCC 33209]
Length=225

 Score = 59.3 bits (142),  Expect = 2e-07, Method: Composition-based stats.
 Identities = 25/38 (66%), Positives = 30/38 (79%), Gaps = 0/38 (0%)

Query  1    VLIRWHIQLGNIVIPKSVNPMRIASNFDAFDFPRSMTE  38
            V+IRWHIQ+GN+VIPKSV P RIA+N D F+F  S  E
Sbjct  164  VIIRWHIQVGNVVIPKSVTPERIAANIDVFNFELSDAE  201


>gi|333991314|ref|YP_004523928.1| oxidoreductase [Mycobacterium sp. JDM601]
 gi|333487282|gb|AEF36674.1| oxidoreductase [Mycobacterium sp. JDM601]
Length=275

 Score = 59.3 bits (142),  Expect = 2e-07, Method: Composition-based stats.
 Identities = 27/38 (72%), Positives = 29/38 (77%), Gaps = 0/38 (0%)

Query  1    VLIRWHIQLGNIVIPKSVNPMRIASNFDAFDFPRSMTE  38
            VLIRWH+QLGNIVIPKSVNP RI SN + FDF     E
Sbjct  213  VLIRWHLQLGNIVIPKSVNPERIISNVEVFDFELGAAE  250


>gi|14587002|gb|AAK70423.1|AF385140_3 2,5-diketo-D-gluconic acid reductase [uncultured bacterium]
Length=275

 Score = 58.9 bits (141),  Expect = 2e-07, Method: Compositional matrix adjust.
 Identities = 24/35 (69%), Positives = 29/35 (83%), Gaps = 0/35 (0%)

Query  1    VLIRWHIQLGNIVIPKSVNPMRIASNFDAFDFPRS  35
            V+IRWH+Q+GN+VIPKS NP R+A NFD FDF  S
Sbjct  217  VIIRWHLQIGNLVIPKSSNPXRLAXNFDVFDFELS  251


>gi|50843567|ref|YP_056794.1| 2,5-diketo-D-gluconic acid reductase A [Propionibacterium acnes 
KPA171202]
 gi|282854896|ref|ZP_06264230.1| oxidoreductase, aldo/keto reductase family protein [Propionibacterium 
acnes J139]
 gi|335053379|ref|ZP_08546221.1| 2,5-diketo-D-gluconic acid reductase A [Propionibacterium sp. 
434-HC2]
 12 more sequence titles
 gi|50841169|gb|AAT83836.1| 2,5-diketo-D-gluconic acid reductase A [Propionibacterium acnes 
KPA171202]
 gi|282582042|gb|EFB87425.1| oxidoreductase, aldo/keto reductase family protein [Propionibacterium 
acnes J139]
 gi|314924378|gb|EFS88209.1| oxidoreductase, aldo/keto reductase family protein [Propionibacterium 
acnes HL001PA1]
 gi|314967237|gb|EFT11336.1| oxidoreductase, aldo/keto reductase family protein [Propionibacterium 
acnes HL082PA2]
 gi|314981626|gb|EFT25719.1| oxidoreductase, aldo/keto reductase family protein [Propionibacterium 
acnes HL110PA3]
 gi|315092265|gb|EFT64241.1| oxidoreductase, aldo/keto reductase family protein [Propionibacterium 
acnes HL110PA4]
 gi|315094841|gb|EFT66817.1| oxidoreductase, aldo/keto reductase family protein [Propionibacterium 
acnes HL060PA1]
 gi|315104703|gb|EFT76679.1| oxidoreductase, aldo/keto reductase family protein [Propionibacterium 
acnes HL050PA2]
 gi|315107766|gb|EFT79742.1| oxidoreductase, aldo/keto reductase family protein [Propionibacterium 
acnes HL030PA1]
 gi|327328684|gb|EGE70444.1| 2,5-diketo-D-gluconic acid reductase [Propionibacterium acnes 
HL103PA1]
 gi|333767216|gb|EGL44473.1| 2,5-diketo-D-gluconic acid reductase A [Propionibacterium sp. 
434-HC2]
 gi|335278529|gb|AEH30434.1| 2,5-diketo-D-gluconic acid reductase A [Propionibacterium acnes 
6609]
Length=273

 Score = 58.9 bits (141),  Expect = 3e-07, Method: Composition-based stats.
 Identities = 24/35 (69%), Positives = 28/35 (80%), Gaps = 0/35 (0%)

Query  1    VLIRWHIQLGNIVIPKSVNPMRIASNFDAFDFPRS  35
            V+IRWH+Q+GN+V PKSV P RIA NFD FDF  S
Sbjct  214  VVIRWHLQIGNVVFPKSVTPSRIAENFDVFDFELS  248


>gi|14587009|gb|AAK70427.1|AF385142_1 2,5-diketo-D-gluconic acid reductase [uncultured bacterium]
Length=275

 Score = 58.5 bits (140),  Expect = 3e-07, Method: Compositional matrix adjust.
 Identities = 24/35 (69%), Positives = 29/35 (83%), Gaps = 0/35 (0%)

Query  1    VLIRWHIQLGNIVIPKSVNPMRIASNFDAFDFPRS  35
            V+IRWH+Q+GN+VIPKS NP R+A NFD FDF  S
Sbjct  217  VIIRWHLQIGNLVIPKSSNPDRLAENFDVFDFELS  251


>gi|309813180|ref|ZP_07706902.1| 2,5-diketo-D-gluconic acid reductase A [Dermacoccus sp. Ellin185]
 gi|308432876|gb|EFP56786.1| 2,5-diketo-D-gluconic acid reductase A [Dermacoccus sp. Ellin185]
Length=290

 Score = 58.5 bits (140),  Expect = 3e-07, Method: Composition-based stats.
 Identities = 26/41 (64%), Positives = 31/41 (76%), Gaps = 2/41 (4%)

Query  1    VLIRWHIQLGNIVIPKSVNPMRIASNFDAFDFPRSMTEPGL  41
            V+IRWH+Q+GN+VIPKSV P RIA NFD  DF   +TE  L
Sbjct  231  VIIRWHLQIGNVVIPKSVTPARIAENFDVLDF--ELTEDDL  269


>gi|226304268|ref|YP_002764226.1| morphine 6-dehydrogenase [Rhodococcus erythropolis PR4]
 gi|226183383|dbj|BAH31487.1| putative morphine 6-dehydrogenase [Rhodococcus erythropolis PR4]
Length=293

 Score = 58.2 bits (139),  Expect = 4e-07, Method: Compositional matrix adjust.
 Identities = 25/42 (60%), Positives = 30/42 (72%), Gaps = 0/42 (0%)

Query  1    VLIRWHIQLGNIVIPKSVNPMRIASNFDAFDFPRSMTEPGLV  42
            V++RWH+Q G   IPKSVNP RIASNFD FDF  S  + G +
Sbjct  224  VMLRWHVQEGRSAIPKSVNPERIASNFDVFDFELSTAQLGAI  265


>gi|297161631|gb|ADI11343.1| putative oxidoreductase [Streptomyces bingchenggensis BCW-1]
Length=276

 Score = 58.2 bits (139),  Expect = 4e-07, Method: Composition-based stats.
 Identities = 24/32 (75%), Positives = 27/32 (85%), Gaps = 0/32 (0%)

Query  1    VLIRWHIQLGNIVIPKSVNPMRIASNFDAFDF  32
            V++RWH+QLGNIVIPKSV P RI  NFD FDF
Sbjct  218  VVLRWHLQLGNIVIPKSVTPARIRENFDVFDF  249


>gi|329940292|ref|ZP_08289573.1| oxidoreductase [Streptomyces griseoaurantiacus M045]
 gi|329300353|gb|EGG44250.1| oxidoreductase [Streptomyces griseoaurantiacus M045]
Length=277

 Score = 58.2 bits (139),  Expect = 5e-07, Method: Composition-based stats.
 Identities = 23/32 (72%), Positives = 27/32 (85%), Gaps = 0/32 (0%)

Query  1    VLIRWHIQLGNIVIPKSVNPMRIASNFDAFDF  32
            V++RWH+QLGN+VIPKSV P RI  NFD FDF
Sbjct  218  VVLRWHLQLGNVVIPKSVTPSRIKENFDVFDF  249


>gi|289427854|ref|ZP_06429558.1| oxidoreductase, aldo/keto reductase family protein [Propionibacterium 
acnes J165]
 gi|295131648|ref|YP_003582311.1| oxidoreductase, aldo/keto reductase family protein [Propionibacterium 
acnes SK137]
 gi|335051096|ref|ZP_08544032.1| 2,5-diketo-D-gluconic acid reductase A [Propionibacterium sp. 
409-HC1]
 61 more sequence titles
 gi|342213006|ref|ZP_08705731.1| 2,5-diketo-D-gluconic acid reductase A [Propionibacterium sp. 
CC003-HC2]
 gi|289158737|gb|EFD06937.1| oxidoreductase, aldo/keto reductase family protein [Propionibacterium 
acnes J165]
 gi|291376486|gb|ADE00341.1| oxidoreductase, aldo/keto reductase family protein [Propionibacterium 
acnes SK137]
 gi|313763776|gb|EFS35140.1| oxidoreductase, aldo/keto reductase family protein [Propionibacterium 
acnes HL013PA1]
 gi|313771793|gb|EFS37759.1| oxidoreductase, aldo/keto reductase family protein [Propionibacterium 
acnes HL074PA1]
 gi|313793675|gb|EFS41706.1| oxidoreductase, aldo/keto reductase family protein [Propionibacterium 
acnes HL110PA1]
 gi|313802986|gb|EFS44194.1| oxidoreductase, aldo/keto reductase family protein [Propionibacterium 
acnes HL110PA2]
 gi|313808397|gb|EFS46864.1| oxidoreductase, aldo/keto reductase family protein [Propionibacterium 
acnes HL087PA2]
 gi|313810615|gb|EFS48329.1| oxidoreductase, aldo/keto reductase family protein [Propionibacterium 
acnes HL083PA1]
 gi|313813754|gb|EFS51468.1| oxidoreductase, aldo/keto reductase family protein [Propionibacterium 
acnes HL025PA1]
 gi|313816905|gb|EFS54619.1| oxidoreductase, aldo/keto reductase family protein [Propionibacterium 
acnes HL059PA1]
 gi|313818181|gb|EFS55895.1| oxidoreductase, aldo/keto reductase family protein [Propionibacterium 
acnes HL046PA2]
 gi|313821039|gb|EFS58753.1| oxidoreductase, aldo/keto reductase family protein [Propionibacterium 
acnes HL036PA1]
 gi|313824083|gb|EFS61797.1| oxidoreductase, aldo/keto reductase family protein [Propionibacterium 
acnes HL036PA2]
 gi|313827171|gb|EFS64885.1| oxidoreductase, aldo/keto reductase family protein [Propionibacterium 
acnes HL063PA1]
 gi|313829706|gb|EFS67420.1| oxidoreductase, aldo/keto reductase family protein [Propionibacterium 
acnes HL063PA2]
 gi|313831657|gb|EFS69371.1| oxidoreductase, aldo/keto reductase family protein [Propionibacterium 
acnes HL007PA1]
 gi|313834811|gb|EFS72525.1| oxidoreductase, aldo/keto reductase family protein [Propionibacterium 
acnes HL056PA1]
 gi|313839385|gb|EFS77099.1| oxidoreductase, aldo/keto reductase family protein [Propionibacterium 
acnes HL086PA1]
 gi|314916669|gb|EFS80500.1| oxidoreductase, aldo/keto reductase family protein [Propionibacterium 
acnes HL005PA4]
 gi|314918873|gb|EFS82704.1| oxidoreductase, aldo/keto reductase family protein [Propionibacterium 
acnes HL050PA1]
 gi|314920884|gb|EFS84715.1| oxidoreductase, aldo/keto reductase family protein [Propionibacterium 
acnes HL050PA3]
 gi|314927064|gb|EFS90895.1| oxidoreductase, aldo/keto reductase family protein [Propionibacterium 
acnes HL036PA3]
 gi|314932326|gb|EFS96157.1| oxidoreductase, aldo/keto reductase family protein [Propionibacterium 
acnes HL067PA1]
 gi|314956602|gb|EFT00854.1| oxidoreductase, aldo/keto reductase family protein [Propionibacterium 
acnes HL027PA1]
 gi|314959482|gb|EFT03584.1| oxidoreductase, aldo/keto reductase family protein [Propionibacterium 
acnes HL002PA1]
 gi|314961886|gb|EFT05987.1| oxidoreductase, aldo/keto reductase family protein [Propionibacterium 
acnes HL002PA2]
 gi|314964677|gb|EFT08777.1| oxidoreductase, aldo/keto reductase family protein [Propionibacterium 
acnes HL082PA1]
 gi|314968917|gb|EFT13015.1| oxidoreductase, aldo/keto reductase family protein [Propionibacterium 
acnes HL037PA1]
 gi|314975007|gb|EFT19102.1| oxidoreductase, aldo/keto reductase family protein [Propionibacterium 
acnes HL053PA1]
 gi|314977896|gb|EFT21990.1| oxidoreductase, aldo/keto reductase family protein [Propionibacterium 
acnes HL045PA1]
 gi|314979614|gb|EFT23708.1| oxidoreductase, aldo/keto reductase family protein [Propionibacterium 
acnes HL072PA2]
 gi|314984695|gb|EFT28787.1| oxidoreductase, aldo/keto reductase family protein [Propionibacterium 
acnes HL005PA1]
 gi|314988350|gb|EFT32441.1| oxidoreductase, aldo/keto reductase family protein [Propionibacterium 
acnes HL005PA2]
 gi|314990246|gb|EFT34337.1| oxidoreductase, aldo/keto reductase family protein [Propionibacterium 
acnes HL005PA3]
 gi|315079334|gb|EFT51335.1| oxidoreductase, aldo/keto reductase family protein [Propionibacterium 
acnes HL053PA2]
 gi|315082372|gb|EFT54348.1| oxidoreductase, aldo/keto reductase family protein [Propionibacterium 
acnes HL078PA1]
 gi|315083837|gb|EFT55813.1| oxidoreductase, aldo/keto reductase family protein [Propionibacterium 
acnes HL027PA2]
 gi|315087296|gb|EFT59272.1| oxidoreductase, aldo/keto reductase family protein [Propionibacterium 
acnes HL002PA3]
 gi|315089714|gb|EFT61690.1| oxidoreductase, aldo/keto reductase family protein [Propionibacterium 
acnes HL072PA1]
 gi|315095587|gb|EFT67563.1| oxidoreductase, aldo/keto reductase family protein [Propionibacterium 
acnes HL038PA1]
 gi|315100251|gb|EFT72227.1| oxidoreductase, aldo/keto reductase family protein [Propionibacterium 
acnes HL059PA2]
 gi|315102575|gb|EFT74551.1| oxidoreductase, aldo/keto reductase family protein [Propionibacterium 
acnes HL046PA1]
 gi|315109665|gb|EFT81641.1| oxidoreductase, aldo/keto reductase family protein [Propionibacterium 
acnes HL030PA2]
 gi|327326623|gb|EGE68411.1| 2,5-diketo-D-gluconic acid reductase [Propionibacterium acnes 
HL096PA3]
 gi|327332887|gb|EGE74619.1| 2,5-diketo-D-gluconic acid reductase [Propionibacterium acnes 
HL096PA2]
 gi|327335291|gb|EGE77001.1| 2,5-diketo-D-gluconic acid reductase [Propionibacterium acnes 
HL097PA1]
 gi|327447715|gb|EGE94369.1| oxidoreductase, aldo/keto reductase family protein [Propionibacterium 
acnes HL043PA2]
 gi|327448590|gb|EGE95244.1| oxidoreductase, aldo/keto reductase family protein [Propionibacterium 
acnes HL043PA1]
 gi|327449558|gb|EGE96212.1| oxidoreductase, aldo/keto reductase family protein [Propionibacterium 
acnes HL013PA2]
 gi|327455901|gb|EGF02556.1| oxidoreductase, aldo/keto reductase family protein [Propionibacterium 
acnes HL087PA3]
 gi|327456006|gb|EGF02661.1| oxidoreductase, aldo/keto reductase family protein [Propionibacterium 
acnes HL092PA1]
 gi|327458053|gb|EGF04708.1| oxidoreductase, aldo/keto reductase family protein [Propionibacterium 
acnes HL083PA2]
 gi|328757214|gb|EGF70830.1| oxidoreductase, aldo/keto reductase family protein [Propionibacterium 
acnes HL087PA1]
 gi|328757405|gb|EGF71021.1| oxidoreductase, aldo/keto reductase family protein [Propionibacterium 
acnes HL020PA1]
 gi|328757597|gb|EGF71213.1| oxidoreductase, aldo/keto reductase family protein [Propionibacterium 
acnes HL025PA2]
 gi|328762013|gb|EGF75519.1| 2,5-diketo-D-gluconic acid reductase [Propionibacterium acnes 
HL099PA1]
 gi|332676511|gb|AEE73327.1| 2,5-diketo-D-gluconic acid reductase A [Propionibacterium acnes 
266]
 gi|333767914|gb|EGL45130.1| 2,5-diketo-D-gluconic acid reductase A [Propionibacterium sp. 
409-HC1]
 gi|340768550|gb|EGR91075.1| 2,5-diketo-D-gluconic acid reductase A [Propionibacterium sp. 
CC003-HC2]
 gi|340769642|gb|EGR92164.1| 2,5-diketo-D-gluconic acid reductase A [Propionibacterium acnes 
SK182]
Length=273

 Score = 57.4 bits (137),  Expect = 6e-07, Method: Composition-based stats.
 Identities = 24/35 (69%), Positives = 27/35 (78%), Gaps = 0/35 (0%)

Query  1    VLIRWHIQLGNIVIPKSVNPMRIASNFDAFDFPRS  35
            V+IRWH+Q+GNIV PKSV P RI  NFD FDF  S
Sbjct  214  VVIRWHLQIGNIVFPKSVTPSRIVENFDVFDFELS  248


>gi|269125831|ref|YP_003299201.1| 2,5-didehydrogluconate reductase [Thermomonospora curvata DSM 
43183]
 gi|268310789|gb|ACY97163.1| 2,5-didehydrogluconate reductase [Thermomonospora curvata DSM 
43183]
Length=276

 Score = 57.4 bits (137),  Expect = 7e-07, Method: Compositional matrix adjust.
 Identities = 24/32 (75%), Positives = 27/32 (85%), Gaps = 0/32 (0%)

Query  1    VLIRWHIQLGNIVIPKSVNPMRIASNFDAFDF  32
            V++RWH+QLGNIVIPKSV P RIA NF  FDF
Sbjct  216  VVLRWHLQLGNIVIPKSVTPSRIAENFQVFDF  247


>gi|229488912|ref|ZP_04382778.1| 2,5-diketo-D-gluconic acid reductase A [Rhodococcus erythropolis 
SK121]
 gi|229324416|gb|EEN90171.1| 2,5-diketo-D-gluconic acid reductase A [Rhodococcus erythropolis 
SK121]
Length=293

 Score = 57.4 bits (137),  Expect = 8e-07, Method: Composition-based stats.
 Identities = 23/32 (72%), Positives = 28/32 (88%), Gaps = 0/32 (0%)

Query  1    VLIRWHIQLGNIVIPKSVNPMRIASNFDAFDF  32
            V+IRWH+Q+GN+VIPKSV P RIA+NFD F F
Sbjct  233  VIIRWHLQIGNVVIPKSVTPERIAANFDVFGF  264


>gi|291299234|ref|YP_003510512.1| 2,5-didehydrogluconate reductase [Stackebrandtia nassauensis 
DSM 44728]
 gi|290568454|gb|ADD41419.1| 2,5-didehydrogluconate reductase [Stackebrandtia nassauensis 
DSM 44728]
Length=276

 Score = 57.0 bits (136),  Expect = 8e-07, Method: Composition-based stats.
 Identities = 23/32 (72%), Positives = 26/32 (82%), Gaps = 0/32 (0%)

Query  1    VLIRWHIQLGNIVIPKSVNPMRIASNFDAFDF  32
            V++RWHIQLGN+VIPKSV P RI  N D FDF
Sbjct  217  VVLRWHIQLGNVVIPKSVTPSRIVENIDVFDF  248


>gi|54022639|ref|YP_116881.1| putative oxidoreductase [Nocardia farcinica IFM 10152]
 gi|54014147|dbj|BAD55517.1| putative oxidoreductase [Nocardia farcinica IFM 10152]
Length=283

 Score = 57.0 bits (136),  Expect = 9e-07, Method: Compositional matrix adjust.
 Identities = 24/35 (69%), Positives = 28/35 (80%), Gaps = 0/35 (0%)

Query  1    VLIRWHIQLGNIVIPKSVNPMRIASNFDAFDFPRS  35
            V+IRWH+QLGN+VIPKSV P RI +NFD F F  S
Sbjct  222  VIIRWHLQLGNVVIPKSVTPARIEANFDVFGFELS  256


>gi|284041555|ref|YP_003391895.1| aldo/keto reductase [Conexibacter woesei DSM 14684]
 gi|283945776|gb|ADB48520.1| aldo/keto reductase [Conexibacter woesei DSM 14684]
Length=276

 Score = 57.0 bits (136),  Expect = 9e-07, Method: Composition-based stats.
 Identities = 24/35 (69%), Positives = 28/35 (80%), Gaps = 0/35 (0%)

Query  1    VLIRWHIQLGNIVIPKSVNPMRIASNFDAFDFPRS  35
            V++RWH+QLGN+VIPKSV P RIA N D FDF  S
Sbjct  216  VVLRWHLQLGNVVIPKSVTPARIAENLDVFDFALS  250


>gi|333918533|ref|YP_004492114.1| putative 2,5-diketo-D-gluconate reductase [Amycolicicoccus subflavus 
DQS3-9A1]
 gi|333480754|gb|AEF39314.1| Putative 2,5-diketo-D-gluconate reductase [Amycolicicoccus subflavus 
DQS3-9A1]
Length=277

 Score = 56.6 bits (135),  Expect = 1e-06, Method: Composition-based stats.
 Identities = 24/42 (58%), Positives = 30/42 (72%), Gaps = 0/42 (0%)

Query  1    VLIRWHIQLGNIVIPKSVNPMRIASNFDAFDFPRSMTEPGLV  42
            V++RWH+QLGN+VIPKSV P RI  N D FDF  S  + G +
Sbjct  219  VILRWHLQLGNVVIPKSVTPRRIRENLDVFDFELSDEQVGAI  260


>gi|226308044|ref|YP_002768004.1| 2,5-diketo-D-gluconate reductase [Rhodococcus erythropolis PR4]
 gi|226187161|dbj|BAH35265.1| putative 2,5-diketo-D-gluconate reductase [Rhodococcus erythropolis 
PR4]
Length=276

 Score = 56.6 bits (135),  Expect = 1e-06, Method: Composition-based stats.
 Identities = 23/32 (72%), Positives = 28/32 (88%), Gaps = 0/32 (0%)

Query  1    VLIRWHIQLGNIVIPKSVNPMRIASNFDAFDF  32
            V+IRWH+Q+GN+VIPKSV P RIA+NFD F F
Sbjct  216  VIIRWHLQIGNVVIPKSVTPDRIAANFDVFGF  247


>gi|297584691|ref|YP_003700471.1| 2,5-didehydrogluconate reductase [Bacillus selenitireducens MLS10]
 gi|297143148|gb|ADH99905.1| 2,5-didehydrogluconate reductase [Bacillus selenitireducens MLS10]
Length=274

 Score = 56.6 bits (135),  Expect = 1e-06, Method: Composition-based stats.
 Identities = 23/32 (72%), Positives = 26/32 (82%), Gaps = 0/32 (0%)

Query  1    VLIRWHIQLGNIVIPKSVNPMRIASNFDAFDF  32
            V+IRWH+Q G+IVIPKSV P RI  NFD FDF
Sbjct  214  VIIRWHMQRGHIVIPKSVTPHRIEENFDVFDF  245


>gi|302524709|ref|ZP_07277051.1| oxidoreductase [Streptomyces sp. AA4]
 gi|302433604|gb|EFL05420.1| oxidoreductase [Streptomyces sp. AA4]
Length=276

 Score = 56.6 bits (135),  Expect = 1e-06, Method: Composition-based stats.
 Identities = 26/44 (60%), Positives = 32/44 (73%), Gaps = 2/44 (4%)

Query  1    VLIRWHIQLGNIVIPKSVNPMRIASNFDAFDFPRSMTEPGLVRI  44
            V++RWH+QLGNIVIPKSV P RI  N D FDF  ++T+  L  I
Sbjct  218  VVLRWHLQLGNIVIPKSVTPARIRQNLDVFDF--ALTDDDLAAI  259


>gi|153010336|ref|YP_001371550.1| 2,5-didehydrogluconate reductase [Ochrobactrum anthropi ATCC 
49188]
 gi|151562224|gb|ABS15721.1| 2,5-didehydrogluconate reductase [Ochrobactrum anthropi ATCC 
49188]
Length=276

 Score = 56.6 bits (135),  Expect = 1e-06, Method: Composition-based stats.
 Identities = 22/32 (69%), Positives = 26/32 (82%), Gaps = 0/32 (0%)

Query  1    VLIRWHIQLGNIVIPKSVNPMRIASNFDAFDF  32
            +++RWHI+ GNIVIPKSV P RI  NFD FDF
Sbjct  215  IILRWHIETGNIVIPKSVTPARIKENFDIFDF  246


>gi|239833526|ref|ZP_04681854.1| 2,5-diketo-D-gluconic acid reductase A [Ochrobactrum intermedium 
LMG 3301]
 gi|239821589|gb|EEQ93158.1| 2,5-diketo-D-gluconic acid reductase A [Ochrobactrum intermedium 
LMG 3301]
Length=276

 Score = 56.6 bits (135),  Expect = 1e-06, Method: Composition-based stats.
 Identities = 22/32 (69%), Positives = 26/32 (82%), Gaps = 0/32 (0%)

Query  1    VLIRWHIQLGNIVIPKSVNPMRIASNFDAFDF  32
            +++RWHI+ GNIVIPKSV P RI  NFD FDF
Sbjct  215  IILRWHIETGNIVIPKSVTPARIKENFDIFDF  246


>gi|331699333|ref|YP_004335572.1| 2,5-didehydrogluconate reductase [Pseudonocardia dioxanivorans 
CB1190]
 gi|326954022|gb|AEA27719.1| 2,5-didehydrogluconate reductase [Pseudonocardia dioxanivorans 
CB1190]
Length=275

 Score = 56.2 bits (134),  Expect = 1e-06, Method: Composition-based stats.
 Identities = 25/42 (60%), Positives = 28/42 (67%), Gaps = 0/42 (0%)

Query  1    VLIRWHIQLGNIVIPKSVNPMRIASNFDAFDFPRSMTEPGLV  42
            V++RWH+QLGNIV PKSV P RI  N D FDF  S  E   V
Sbjct  217  VVLRWHVQLGNIVFPKSVTPSRIRENIDVFDFALSDEEMATV  258


>gi|289426055|ref|ZP_06427802.1| oxidoreductase, aldo/keto reductase family protein [Propionibacterium 
acnes SK187]
 gi|289153598|gb|EFD02312.1| oxidoreductase, aldo/keto reductase family protein [Propionibacterium 
acnes SK187]
Length=280

 Score = 56.2 bits (134),  Expect = 1e-06, Method: Compositional matrix adjust.
 Identities = 24/35 (69%), Positives = 27/35 (78%), Gaps = 0/35 (0%)

Query  1    VLIRWHIQLGNIVIPKSVNPMRIASNFDAFDFPRS  35
            V+IRWH+Q+GNIV PKSV P RI  NFD FDF  S
Sbjct  221  VVIRWHLQIGNIVFPKSVTPSRIVENFDVFDFELS  255


>gi|296138592|ref|YP_003645835.1| aldo/keto reductase [Tsukamurella paurometabola DSM 20162]
 gi|296026726|gb|ADG77496.1| aldo/keto reductase [Tsukamurella paurometabola DSM 20162]
Length=274

 Score = 56.2 bits (134),  Expect = 1e-06, Method: Composition-based stats.
 Identities = 23/37 (63%), Positives = 28/37 (76%), Gaps = 0/37 (0%)

Query  2    LIRWHIQLGNIVIPKSVNPMRIASNFDAFDFPRSMTE  38
            ++RWH+QLGN+VIPKSV P RIA NFD F F  +  E
Sbjct  216  ILRWHLQLGNVVIPKSVTPSRIAENFDVFGFELTADE  252


>gi|317506058|ref|ZP_07963886.1| aldo/keto reductase [Segniliparus rugosus ATCC BAA-974]
 gi|316255630|gb|EFV14872.1| aldo/keto reductase [Segniliparus rugosus ATCC BAA-974]
Length=281

 Score = 56.2 bits (134),  Expect = 2e-06, Method: Composition-based stats.
 Identities = 26/44 (60%), Positives = 33/44 (75%), Gaps = 2/44 (4%)

Query  1    VLIRWHIQLGNIVIPKSVNPMRIASNFDAFDFPRSMTEPGLVRI  44
            V++RWH+QLGNIVIPKS  P RIA+NF+ FDF   +T   + RI
Sbjct  217  VILRWHLQLGNIVIPKSQTPERIAANFEVFDF--ELTPEQVARI  258


>gi|302566267|pdb|3O0K|A Chain A, Crystal Structure Of AldoKETO REDUCTASE FROM BRUCELLA 
MELITENSIS
 gi|302566268|pdb|3O0K|B Chain B, Crystal Structure Of AldoKETO REDUCTASE FROM BRUCELLA 
MELITENSIS
 gi|302566269|pdb|3O0K|C Chain C, Crystal Structure Of AldoKETO REDUCTASE FROM BRUCELLA 
MELITENSIS
 gi|302566270|pdb|3O0K|D Chain D, Crystal Structure Of AldoKETO REDUCTASE FROM BRUCELLA 
MELITENSIS
Length=283

 Score = 56.2 bits (134),  Expect = 2e-06, Method: Composition-based stats.
 Identities = 22/38 (58%), Positives = 29/38 (77%), Gaps = 0/38 (0%)

Query  1    VLIRWHIQLGNIVIPKSVNPMRIASNFDAFDFPRSMTE  38
            +++RWHI+ GNIVIPKS+ P RI  NFD FDF  + T+
Sbjct  238  IILRWHIETGNIVIPKSITPARIKENFDIFDFTLNGTD  275


>gi|294853201|ref|ZP_06793873.1| aldo/keto reductase [Brucella sp. NVSL 07-0026]
 gi|294818856|gb|EFG35856.1| aldo/keto reductase [Brucella sp. NVSL 07-0026]
Length=275

 Score = 56.2 bits (134),  Expect = 2e-06, Method: Compositional matrix adjust.
 Identities = 22/38 (58%), Positives = 30/38 (79%), Gaps = 0/38 (0%)

Query  1    VLIRWHIQLGNIVIPKSVNPMRIASNFDAFDFPRSMTE  38
            +++RWHI++GNIVIPKS+ P RI  NFD FDF  + T+
Sbjct  215  IILRWHIEIGNIVIPKSITPARIKENFDIFDFTLNGTD  252


>gi|297562467|ref|YP_003681441.1| 2,5-didehydrogluconate reductase [Nocardiopsis dassonvillei subsp. 
dassonvillei DSM 43111]
 gi|296846915|gb|ADH68935.1| 2,5-didehydrogluconate reductase [Nocardiopsis dassonvillei subsp. 
dassonvillei DSM 43111]
Length=272

 Score = 55.8 bits (133),  Expect = 2e-06, Method: Composition-based stats.
 Identities = 23/35 (66%), Positives = 27/35 (78%), Gaps = 0/35 (0%)

Query  1    VLIRWHIQLGNIVIPKSVNPMRIASNFDAFDFPRS  35
            V++RWH+QLGN+VIPKSV P RI  NFD F F  S
Sbjct  214  VVLRWHLQLGNVVIPKSVTPSRIRENFDVFGFELS  248


>gi|328880228|emb|CCA53467.1| oxidoreductase of aldo or keto reductase family,subgroup 1 [Streptomyces 
venezuelae ATCC 10712]
Length=274

 Score = 55.8 bits (133),  Expect = 2e-06, Method: Composition-based stats.
 Identities = 24/38 (64%), Positives = 28/38 (74%), Gaps = 0/38 (0%)

Query  1    VLIRWHIQLGNIVIPKSVNPMRIASNFDAFDFPRSMTE  38
            V++RWH+QLGN+VIPKSV P RI  N D FDF  S  E
Sbjct  216  VVLRWHLQLGNVVIPKSVTPARIRENIDVFDFALSDEE  253


>gi|313836271|gb|EFS73985.1| oxidoreductase, aldo/keto reductase family protein [Propionibacterium 
acnes HL037PA2]
 gi|314928736|gb|EFS92567.1| oxidoreductase, aldo/keto reductase family protein [Propionibacterium 
acnes HL044PA1]
 gi|314971228|gb|EFT15326.1| oxidoreductase, aldo/keto reductase family protein [Propionibacterium 
acnes HL037PA3]
 gi|328906515|gb|EGG26290.1| 2,5-diketo-D-gluconic acid reductase A [Propionibacterium humerusii 
P08]
Length=273

 Score = 55.8 bits (133),  Expect = 2e-06, Method: Composition-based stats.
 Identities = 23/35 (66%), Positives = 27/35 (78%), Gaps = 0/35 (0%)

Query  1    VLIRWHIQLGNIVIPKSVNPMRIASNFDAFDFPRS  35
            V+IRWH+Q+GN+V PKSV P RIA NFD F F  S
Sbjct  214  VVIRWHLQIGNVVFPKSVTPSRIAENFDVFGFELS  248


>gi|325001278|ref|ZP_08122390.1| 2,5-diketo-D-gluconic acid reductase [Pseudonocardia sp. P1]
Length=274

 Score = 55.8 bits (133),  Expect = 2e-06, Method: Composition-based stats.
 Identities = 26/46 (57%), Positives = 33/46 (72%), Gaps = 2/46 (4%)

Query  1    VLIRWHIQLGNIVIPKSVNPMRIASNFDAFDFPRSMTEPGLVRIRK  46
            V++RWHIQLGNIV PKS +P RI  NF+ FDF  S+T+  +  I K
Sbjct  216  VVLRWHIQLGNIVFPKSNDPGRIKENFEIFDF--SLTDDDIASIEK  259


>gi|306840986|ref|ZP_07473727.1| aldo/keto reductase family oxidoreductase [Brucella sp. BO2]
 gi|306289043|gb|EFM60308.1| aldo/keto reductase family oxidoreductase [Brucella sp. BO2]
Length=275

 Score = 55.8 bits (133),  Expect = 2e-06, Method: Composition-based stats.
 Identities = 22/38 (58%), Positives = 29/38 (77%), Gaps = 0/38 (0%)

Query  1    VLIRWHIQLGNIVIPKSVNPMRIASNFDAFDFPRSMTE  38
            +++RWHI+ GNIVIPKS+ P RI  NFD FDF  + T+
Sbjct  215  IILRWHIETGNIVIPKSITPARIKENFDIFDFTLNGTD  252


>gi|306845501|ref|ZP_07478070.1| aldo/keto reductase family oxidoreductase [Brucella sp. BO1]
 gi|306273822|gb|EFM55649.1| aldo/keto reductase family oxidoreductase [Brucella sp. BO1]
Length=275

 Score = 55.8 bits (133),  Expect = 2e-06, Method: Composition-based stats.
 Identities = 22/38 (58%), Positives = 29/38 (77%), Gaps = 0/38 (0%)

Query  1    VLIRWHIQLGNIVIPKSVNPMRIASNFDAFDFPRSMTE  38
            +++RWHI+ GNIVIPKS+ P RI  NFD FDF  + T+
Sbjct  215  IILRWHIETGNIVIPKSITPARIKENFDIFDFTLNGTD  252


>gi|320006896|gb|ADW01746.1| Methylglyoxal reductase (NADPH-dependent) [Streptomyces flavogriseus 
ATCC 33331]
Length=274

 Score = 55.8 bits (133),  Expect = 2e-06, Method: Composition-based stats.
 Identities = 23/35 (66%), Positives = 27/35 (78%), Gaps = 0/35 (0%)

Query  1    VLIRWHIQLGNIVIPKSVNPMRIASNFDAFDFPRS  35
            V++RWH+QLGN+VIPKSV P RI  N D FDF  S
Sbjct  216  VVLRWHLQLGNVVIPKSVTPARIRQNIDVFDFELS  250


>gi|62317130|ref|YP_222983.1| aldo/keto reductase family oxidoreductase [Brucella abortus bv. 
1 str. 9-941]
 gi|189022392|ref|YP_001932133.1| Aldo/keto reductase [Brucella abortus S19]
 gi|225686038|ref|YP_002734010.1| 2,5-diketo-D-gluconic acid reductase A [Brucella melitensis ATCC 
23457]
 21 more sequence titles
 gi|256014969|ref|YP_003104978.1| oxidoreductase, aldo/keto reductase family [Brucella microti 
CCM 4915]
 gi|256262839|ref|ZP_05465371.1| aldo/keto reductase [Brucella melitensis bv. 2 str. 63/9]
 gi|260544367|ref|ZP_05820188.1| aldo/keto reductase [Brucella abortus NCTC 8038]
 gi|260564328|ref|ZP_05834813.1| aldo/keto reductase [Brucella melitensis bv. 1 str. 16M]
 gi|260882808|ref|ZP_05894422.1| 2,5-didehydrogluconate reductase [Brucella abortus bv. 9 str. 
C68]
 gi|261323550|ref|ZP_05962747.1| 2,5-didehydrogluconate reductase [Brucella neotomae 5K33]
 gi|261756352|ref|ZP_06000061.1| aldo/keto reductase [Brucella sp. F5/99]
 gi|340791941|ref|YP_004757405.1| oxidoreductase, aldo/keto reductase family [Brucella pinnipedialis 
B2/94]
 gi|62197323|gb|AAX75622.1| oxidoreductase, aldo/keto reductase family [Brucella abortus 
bv. 1 str. 9-941]
 gi|189020966|gb|ACD73687.1| Aldo/keto reductase [Brucella abortus S19]
 gi|225642143|gb|ACO02056.1| 2,5-diketo-D-gluconic acid reductase A [Brucella melitensis ATCC 
23457]
 gi|255997629|gb|ACU49316.1| oxidoreductase, aldo/keto reductase family [Brucella microti 
CCM 4915]
 gi|260097638|gb|EEW81512.1| aldo/keto reductase [Brucella abortus NCTC 8038]
 gi|260151971|gb|EEW87064.1| aldo/keto reductase [Brucella melitensis bv. 1 str. 16M]
 gi|260872336|gb|EEX79405.1| 2,5-didehydrogluconate reductase [Brucella abortus bv. 9 str. 
C68]
 gi|261299530|gb|EEY03027.1| 2,5-didehydrogluconate reductase [Brucella neotomae 5K33]
 gi|261736336|gb|EEY24332.1| aldo/keto reductase [Brucella sp. F5/99]
 gi|263092661|gb|EEZ16882.1| aldo/keto reductase [Brucella melitensis bv. 2 str. 63/9]
 gi|326410363|gb|ADZ67427.1| Aldo/keto reductase [Brucella melitensis M28]
 gi|326553656|gb|ADZ88295.1| Aldo/keto reductase [Brucella melitensis M5-90]
 gi|340560400|gb|AEK55637.1| oxidoreductase, aldo/keto reductase family [Brucella pinnipedialis 
B2/94]
Length=275

 Score = 55.8 bits (133),  Expect = 2e-06, Method: Composition-based stats.
 Identities = 22/38 (58%), Positives = 29/38 (77%), Gaps = 0/38 (0%)

Query  1    VLIRWHIQLGNIVIPKSVNPMRIASNFDAFDFPRSMTE  38
            +++RWHI+ GNIVIPKS+ P RI  NFD FDF  + T+
Sbjct  215  IILRWHIETGNIVIPKSITPARIKENFDIFDFTLNGTD  252


>gi|23499945|ref|NP_699385.1| aldo/keto reductase family oxidoreductase [Brucella suis 1330]
 gi|161620263|ref|YP_001594149.1| 2,5-diketo-D-gluconic acid reductase A [Brucella canis ATCC 23365]
 gi|163844372|ref|YP_001622027.1| hypothetical protein BSUIS_B0186 [Brucella suis ATCC 23445]
 6 more sequence titles
 gi|260568491|ref|ZP_05838960.1| aldo/keto reductase [Brucella suis bv. 4 str. 40]
 gi|23463524|gb|AAN33390.1| oxidoreductase, aldo/keto reductase family [Brucella suis 1330]
 gi|161337074|gb|ABX63378.1| 2,5-diketo-D-gluconic acid reductase A [Brucella canis ATCC 23365]
 gi|163675095|gb|ABY39205.1| Hypothetical protein, conserved [Brucella suis ATCC 23445]
 gi|260155156|gb|EEW90237.1| aldo/keto reductase [Brucella suis bv. 4 str. 40]
 gi|343384176|gb|AEM19667.1| aldo/keto reductase family oxidoreductase [Brucella suis 1330]
Length=275

 Score = 55.8 bits (133),  Expect = 2e-06, Method: Composition-based stats.
 Identities = 22/38 (58%), Positives = 29/38 (77%), Gaps = 0/38 (0%)

Query  1    VLIRWHIQLGNIVIPKSVNPMRIASNFDAFDFPRSMTE  38
            +++RWHI+ GNIVIPKS+ P RI  NFD FDF  + T+
Sbjct  215  IILRWHIETGNIVIPKSITPARIKENFDIFDFTLNGTD  252



Lambda     K      H
   0.324    0.138    0.417 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Effective search space used: 129010837482


  Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
    Posted date:  Sep 5, 2011  4:36 AM
  Number of letters in database: 5,219,829,388
  Number of sequences in database:  15,229,318



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40