BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv2981c Length=373 Score E Sequences producing significant alignments: (Bits) Value gi|15610118|ref|NP_217497.1| D-alanyl-alanine synthetase A [Myco... 745 0.0 gi|15842537|ref|NP_337574.1| D-alanyl-alanine synthetase A [Myco... 744 0.0 gi|340627970|ref|YP_004746422.1| putative D-alanine--D-alanine l... 740 0.0 gi|31794157|ref|NP_856650.1| D-alanyl-alanine synthetase A [Myco... 731 0.0 gi|167969998|ref|ZP_02552275.1| D-alanyl-alanine synthetase A [M... 717 0.0 gi|253797926|ref|YP_003030927.1| D-alanine-D-alanine ligase ddlA... 715 0.0 gi|289575688|ref|ZP_06455915.1| D-alanyl-alanine synthetase A [M... 707 0.0 gi|289746785|ref|ZP_06506163.1| D-alanyl-alanine synthetase A [M... 667 0.0 gi|183981746|ref|YP_001850037.1| d-alanine--D-alanine ligase Ddl... 640 0.0 gi|118617561|ref|YP_905893.1| D-alanyl-alanine synthetase A [Myc... 637 0.0 gi|254819105|ref|ZP_05224106.1| D-alanyl-alanine synthetase A [M... 637 0.0 gi|342858192|ref|ZP_08714847.1| D-alanyl-alanine synthetase A [M... 634 6e-180 gi|41409117|ref|NP_961953.1| D-alanyl-alanine synthetase A [Myco... 631 5e-179 gi|118464178|ref|YP_883000.1| D-alanyl-alanine synthetase A [Myc... 629 2e-178 gi|240168958|ref|ZP_04747617.1| D-alanyl-alanine synthetase A [M... 620 1e-175 gi|15827889|ref|NP_302152.1| D-alanyl-alanine synthetase A [Myco... 608 4e-172 gi|296171291|ref|ZP_06852695.1| D-alanine-D-alanine ligase [Myco... 605 3e-171 gi|108798897|ref|YP_639094.1| D-alanyl-alanine synthetase A [Myc... 586 2e-165 gi|145224798|ref|YP_001135476.1| D-alanyl-alanine synthetase A [... 585 3e-165 gi|126434497|ref|YP_001070188.1| D-alanyl-alanine synthetase A [... 585 5e-165 gi|118468335|ref|YP_886735.1| D-alanyl-alanine synthetase A [Myc... 584 8e-165 gi|315445128|ref|YP_004078007.1| D-alanine--D-alanine ligase [My... 582 3e-164 gi|120403135|ref|YP_952964.1| D-alanyl-alanine synthetase A [Myc... 582 5e-164 gi|333991324|ref|YP_004523938.1| d-alanine--D-alanine ligase Ddl... 569 2e-160 gi|169630367|ref|YP_001704016.1| D-alanyl-alanine synthetase A [... 541 5e-152 gi|312140476|ref|YP_004007812.1| d-alanine-d-alanine ligase [Rho... 497 2e-138 gi|111023466|ref|YP_706438.1| D-alanyl-alanine synthetase A [Rho... 496 2e-138 gi|226365967|ref|YP_002783750.1| D-alanyl-alanine synthetase A [... 495 4e-138 gi|325675906|ref|ZP_08155590.1| D-alanine-D-alanine ligase [Rhod... 495 6e-138 gi|226305903|ref|YP_002765863.1| D-alanine--D-alanine ligase [Rh... 492 3e-137 gi|229491375|ref|ZP_04385199.1| D-alanine--D-alanine ligase [Rho... 491 6e-137 gi|54026176|ref|YP_120418.1| D-alanyl-alanine synthetase A [Noca... 488 9e-136 gi|331698554|ref|YP_004334793.1| D-alanine--D-alanine ligase [Ps... 478 1e-132 gi|333920842|ref|YP_004494423.1| D-alanine--D-alanine ligase [Am... 471 8e-131 gi|134102567|ref|YP_001108228.1| D-alanyl-alanine synthetase A [... 459 4e-127 gi|302525004|ref|ZP_07277346.1| D-alanylalanine synthetase [Stre... 449 3e-124 gi|257054969|ref|YP_003132801.1| D-alanyl-alanine synthetase A [... 441 7e-122 gi|300783664|ref|YP_003763955.1| D-alanine-D-alanine ligase [Amy... 436 3e-120 gi|296140535|ref|YP_003647778.1| D-alanine/D-alanine ligase [Tsu... 432 4e-119 gi|256379981|ref|YP_003103641.1| D-alanyl-alanine synthetase A [... 414 2e-113 gi|325000509|ref|ZP_08121621.1| D-alanyl-alanine synthetase A [P... 411 1e-112 gi|330466252|ref|YP_004403995.1| D-alanine--D-alanine ligase [Ve... 405 5e-111 gi|237785790|ref|YP_002906495.1| D-alanyl-alanine synthetase A [... 405 5e-111 gi|145593823|ref|YP_001158120.1| D-alanine--D-alanine ligase [Sa... 401 9e-110 gi|159036808|ref|YP_001536061.1| D-alanine--D-alanine ligase [Sa... 398 8e-109 gi|319951163|ref|ZP_08025008.1| D-alanyl-alanine synthetase A [D... 398 9e-109 gi|258651717|ref|YP_003200873.1| D-alanine/D-alanine ligase [Nak... 397 1e-108 gi|336179523|ref|YP_004584898.1| D-alanine--D-alanine ligase [Fr... 396 4e-108 gi|302865845|ref|YP_003834482.1| D-alanine/D-alanine ligase [Mic... 392 4e-107 gi|238063267|ref|ZP_04607976.1| D-alanine-D-alanine ligase [Micr... 391 1e-106 >gi|15610118|ref|NP_217497.1| D-alanyl-alanine synthetase A [Mycobacterium tuberculosis H37Rv] gi|148662831|ref|YP_001284354.1| D-alanyl-alanine synthetase A [Mycobacterium tuberculosis H37Ra] gi|306777274|ref|ZP_07415611.1| D-alanine-D-alanine ligase ddlA [Mycobacterium tuberculosis SUMu001] 13 more sequence titles Length=373 Score = 745 bits (1924), Expect = 0.0, Method: Compositional matrix adjust. Identities = 372/373 (99%), Positives = 373/373 (100%), Gaps = 0/373 (0%) Query 1 VSANDRRDRRVRVAVVFGGRSNEHAISCVSAGSILRNLDSRRFDVIAVGITPAGSWVLTD 60 +SANDRRDRRVRVAVVFGGRSNEHAISCVSAGSILRNLDSRRFDVIAVGITPAGSWVLTD Sbjct 1 MSANDRRDRRVRVAVVFGGRSNEHAISCVSAGSILRNLDSRRFDVIAVGITPAGSWVLTD 60 Query 61 ANPDALTITNRELPQVKSGSGTELALPADPRRGGQLVSLPPGAGEVLESVDVVFPVLHGP 120 ANPDALTITNRELPQVKSGSGTELALPADPRRGGQLVSLPPGAGEVLESVDVVFPVLHGP Sbjct 61 ANPDALTITNRELPQVKSGSGTELALPADPRRGGQLVSLPPGAGEVLESVDVVFPVLHGP 120 Query 121 YGEDGTIQGLLELAGVPYVGAGVLASAVGMDKEFTKKLLAADGLPVGAYAVLRPPRSTLH 180 YGEDGTIQGLLELAGVPYVGAGVLASAVGMDKEFTKKLLAADGLPVGAYAVLRPPRSTLH Sbjct 121 YGEDGTIQGLLELAGVPYVGAGVLASAVGMDKEFTKKLLAADGLPVGAYAVLRPPRSTLH 180 Query 181 RQECERLGLPVFVKPARGGSSIGVSRVSSWDQLPAAVARARRHDPKVIVEAAISGRELEC 240 RQECERLGLPVFVKPARGGSSIGVSRVSSWDQLPAAVARARRHDPKVIVEAAISGRELEC Sbjct 181 RQECERLGLPVFVKPARGGSSIGVSRVSSWDQLPAAVARARRHDPKVIVEAAISGRELEC 240 Query 241 GVLEMPDGTLEASTLGEIRVAGVRGREDSFYDFATKYLDDAAELDVPAKVDDQVAEAIRQ 300 GVLEMPDGTLEASTLGEIRVAGVRGREDSFYDFATKYLDDAAELDVPAKVDDQVAEAIRQ Sbjct 241 GVLEMPDGTLEASTLGEIRVAGVRGREDSFYDFATKYLDDAAELDVPAKVDDQVAEAIRQ 300 Query 301 LAIRAFAAIDCRGLARVDFFLTDDGPVINEINTMPGFTTISMYPRMWAASGVDYPTLLAT 360 LAIRAFAAIDCRGLARVDFFLTDDGPVINEINTMPGFTTISMYPRMWAASGVDYPTLLAT Sbjct 301 LAIRAFAAIDCRGLARVDFFLTDDGPVINEINTMPGFTTISMYPRMWAASGVDYPTLLAT 360 Query 361 MIETTLARGVGLH 373 MIETTLARGVGLH Sbjct 361 MIETTLARGVGLH 373 >gi|15842537|ref|NP_337574.1| D-alanyl-alanine synthetase A [Mycobacterium tuberculosis CDC1551] gi|121638862|ref|YP_979086.1| D-alanyl-alanine synthetase A [Mycobacterium bovis BCG str. Pasteur 1173P2] gi|148824171|ref|YP_001288925.1| D-alanyl-alanine synthetase A [Mycobacterium tuberculosis F11] 56 more sequence titles Length=373 Score = 744 bits (1920), Expect = 0.0, Method: Compositional matrix adjust. Identities = 371/373 (99%), Positives = 372/373 (99%), Gaps = 0/373 (0%) Query 1 VSANDRRDRRVRVAVVFGGRSNEHAISCVSAGSILRNLDSRRFDVIAVGITPAGSWVLTD 60 +SANDRRDRRVRVAVVFGGRSNEHAISCVSAGSILRNLDSRRFDVIAVGITPAGSWVLTD Sbjct 1 MSANDRRDRRVRVAVVFGGRSNEHAISCVSAGSILRNLDSRRFDVIAVGITPAGSWVLTD 60 Query 61 ANPDALTITNRELPQVKSGSGTELALPADPRRGGQLVSLPPGAGEVLESVDVVFPVLHGP 120 ANPDALTITNRELPQVKSGSGTELALPADPRRGGQLVSLPPGAGEVLESVDVVFPVLHGP Sbjct 61 ANPDALTITNRELPQVKSGSGTELALPADPRRGGQLVSLPPGAGEVLESVDVVFPVLHGP 120 Query 121 YGEDGTIQGLLELAGVPYVGAGVLASAVGMDKEFTKKLLAADGLPVGAYAVLRPPRSTLH 180 YGEDGTIQGLLELAGVPYVGAGVLASAVGMDKEFTKKLLAADGLPVGAYAVLRPPRSTLH Sbjct 121 YGEDGTIQGLLELAGVPYVGAGVLASAVGMDKEFTKKLLAADGLPVGAYAVLRPPRSTLH 180 Query 181 RQECERLGLPVFVKPARGGSSIGVSRVSSWDQLPAAVARARRHDPKVIVEAAISGRELEC 240 RQECERLGLPVFVKPARGGSSIGVSRVSSWDQLPAAVARARRHDPKVIVEAAISGRELEC Sbjct 181 RQECERLGLPVFVKPARGGSSIGVSRVSSWDQLPAAVARARRHDPKVIVEAAISGRELEC 240 Query 241 GVLEMPDGTLEASTLGEIRVAGVRGREDSFYDFATKYLDDAAELDVPAKVDDQVAEAIRQ 300 GVLEMPDGTLEASTLGEIRVAGVRGREDSFYDFATKYLDDAAELDVPAKVDDQVAEAIRQ Sbjct 241 GVLEMPDGTLEASTLGEIRVAGVRGREDSFYDFATKYLDDAAELDVPAKVDDQVAEAIRQ 300 Query 301 LAIRAFAAIDCRGLARVDFFLTDDGPVINEINTMPGFTTISMYPRMWAASGVDYPTLLAT 360 LAIRAFAAIDCRGLARVDFFLTDDGPVINEINTMPGFTTISMYPRMWAASGVDYPTLLAT Sbjct 301 LAIRAFAAIDCRGLARVDFFLTDDGPVINEINTMPGFTTISMYPRMWAASGVDYPTLLAT 360 Query 361 MIETTLARGVGLH 373 MIET LARGVGLH Sbjct 361 MIETALARGVGLH 373 >gi|340627970|ref|YP_004746422.1| putative D-alanine--D-alanine ligase DDLA [Mycobacterium canettii CIPT 140010059] gi|340006160|emb|CCC45334.1| putative D-alanine--D-alanine ligase DDLA (D-alanylalanine synthetase) (D-ALA-D-ALA ligase) [Mycobacterium canettii CIPT 140010059] Length=373 Score = 740 bits (1911), Expect = 0.0, Method: Compositional matrix adjust. Identities = 369/373 (99%), Positives = 371/373 (99%), Gaps = 0/373 (0%) Query 1 VSANDRRDRRVRVAVVFGGRSNEHAISCVSAGSILRNLDSRRFDVIAVGITPAGSWVLTD 60 +SAND+RDRRVRVAVVFGGRSNEHAISCVSAGSILRNLDSRRFDVIAVGITPAGSWVLTD Sbjct 1 MSANDQRDRRVRVAVVFGGRSNEHAISCVSAGSILRNLDSRRFDVIAVGITPAGSWVLTD 60 Query 61 ANPDALTITNRELPQVKSGSGTELALPADPRRGGQLVSLPPGAGEVLESVDVVFPVLHGP 120 ANPDAL ITNRELPQVKSGSGTELALPADPRRGGQLVSLPPGAGEVLESVDVVFPVLHGP Sbjct 61 ANPDALAITNRELPQVKSGSGTELALPADPRRGGQLVSLPPGAGEVLESVDVVFPVLHGP 120 Query 121 YGEDGTIQGLLELAGVPYVGAGVLASAVGMDKEFTKKLLAADGLPVGAYAVLRPPRSTLH 180 YGEDGTIQGLLELAGVPYVGAGVLASAVGMDKEFTKKLLAADGLPVGAYAVLRPPRSTLH Sbjct 121 YGEDGTIQGLLELAGVPYVGAGVLASAVGMDKEFTKKLLAADGLPVGAYAVLRPPRSTLH 180 Query 181 RQECERLGLPVFVKPARGGSSIGVSRVSSWDQLPAAVARARRHDPKVIVEAAISGRELEC 240 RQECERLGLPVFVKPARGGSSIGVSRVSSWDQLPAAVARARRHDPKVIVEAAISGRELEC Sbjct 181 RQECERLGLPVFVKPARGGSSIGVSRVSSWDQLPAAVARARRHDPKVIVEAAISGRELEC 240 Query 241 GVLEMPDGTLEASTLGEIRVAGVRGREDSFYDFATKYLDDAAELDVPAKVDDQVAEAIRQ 300 GVLEMPDGTLEASTLGEIRVAGVRGREDSFYDFATKYLDDAAELDVPAKVDDQVAEAIRQ Sbjct 241 GVLEMPDGTLEASTLGEIRVAGVRGREDSFYDFATKYLDDAAELDVPAKVDDQVAEAIRQ 300 Query 301 LAIRAFAAIDCRGLARVDFFLTDDGPVINEINTMPGFTTISMYPRMWAASGVDYPTLLAT 360 LAIRAFAAIDCRGLARVDFFLTDDGPVINEINTMPGFTTISMYPRMWAASGVDYPTLLAT Sbjct 301 LAIRAFAAIDCRGLARVDFFLTDDGPVINEINTMPGFTTISMYPRMWAASGVDYPTLLAT 360 Query 361 MIETTLARGVGLH 373 MIET LARGVGLH Sbjct 361 MIETALARGVGLH 373 >gi|31794157|ref|NP_856650.1| D-alanyl-alanine synthetase A [Mycobacterium bovis AF2122/97] gi|39930832|sp|Q7TXH9.1|DDL_MYCBO RecName: Full=D-alanine--D-alanine ligase; AltName: Full=D-Ala-D-Ala ligase; AltName: Full=D-alanylalanine synthetase gi|31619752|emb|CAD96692.1| PROBABLE D-ALANINE--D-ALANINE LIGASE DDLA (D-ALANYLALANINE SYNTHETASE) (D-ALA-D-ALA LIGASE) [Mycobacterium bovis AF2122/97] Length=370 Score = 731 bits (1887), Expect = 0.0, Method: Compositional matrix adjust. Identities = 368/373 (99%), Positives = 369/373 (99%), Gaps = 3/373 (0%) Query 1 VSANDRRDRRVRVAVVFGGRSNEHAISCVSAGSILRNLDSRRFDVIAVGITPAGSWVLTD 60 +SANDRR VRVAVVFGGRSNEHAISCVSAGSILRNLDSRRFDVIAVGITPAGSWVLTD Sbjct 1 MSANDRR---VRVAVVFGGRSNEHAISCVSAGSILRNLDSRRFDVIAVGITPAGSWVLTD 57 Query 61 ANPDALTITNRELPQVKSGSGTELALPADPRRGGQLVSLPPGAGEVLESVDVVFPVLHGP 120 ANPDALTITNRELPQVKSGSGTELALPADPRRGGQLVSLPPGAGEVLESVDVVFPVLHGP Sbjct 58 ANPDALTITNRELPQVKSGSGTELALPADPRRGGQLVSLPPGAGEVLESVDVVFPVLHGP 117 Query 121 YGEDGTIQGLLELAGVPYVGAGVLASAVGMDKEFTKKLLAADGLPVGAYAVLRPPRSTLH 180 YGEDGTIQGLLELAGVPYVGAGVLASAVGMDKEFTKKLLAADGLPVGAYAVLRPPRSTLH Sbjct 118 YGEDGTIQGLLELAGVPYVGAGVLASAVGMDKEFTKKLLAADGLPVGAYAVLRPPRSTLH 177 Query 181 RQECERLGLPVFVKPARGGSSIGVSRVSSWDQLPAAVARARRHDPKVIVEAAISGRELEC 240 RQECERLGLPVFVKPARGGSSIGVSRVSSWDQLPAAVARARRHDPKVIVEAAISGRELEC Sbjct 178 RQECERLGLPVFVKPARGGSSIGVSRVSSWDQLPAAVARARRHDPKVIVEAAISGRELEC 237 Query 241 GVLEMPDGTLEASTLGEIRVAGVRGREDSFYDFATKYLDDAAELDVPAKVDDQVAEAIRQ 300 GVLEMPDGTLEASTLGEIRVAGVRGREDSFYDFATKYLDDAAELDVPAKVDDQVAEAIRQ Sbjct 238 GVLEMPDGTLEASTLGEIRVAGVRGREDSFYDFATKYLDDAAELDVPAKVDDQVAEAIRQ 297 Query 301 LAIRAFAAIDCRGLARVDFFLTDDGPVINEINTMPGFTTISMYPRMWAASGVDYPTLLAT 360 LAIRAFAAIDCRGLARVDFFLTDDGPVINEINTMPGFTTISMYPRMWAASGVDYPTLLAT Sbjct 298 LAIRAFAAIDCRGLARVDFFLTDDGPVINEINTMPGFTTISMYPRMWAASGVDYPTLLAT 357 Query 361 MIETTLARGVGLH 373 MIET LARGVGLH Sbjct 358 MIETALARGVGLH 370 >gi|167969998|ref|ZP_02552275.1| D-alanyl-alanine synthetase A [Mycobacterium tuberculosis H37Ra] Length=358 Score = 717 bits (1850), Expect = 0.0, Method: Compositional matrix adjust. Identities = 357/358 (99%), Positives = 358/358 (100%), Gaps = 0/358 (0%) Query 16 VFGGRSNEHAISCVSAGSILRNLDSRRFDVIAVGITPAGSWVLTDANPDALTITNRELPQ 75 +FGGRSNEHAISCVSAGSILRNLDSRRFDVIAVGITPAGSWVLTDANPDALTITNRELPQ Sbjct 1 MFGGRSNEHAISCVSAGSILRNLDSRRFDVIAVGITPAGSWVLTDANPDALTITNRELPQ 60 Query 76 VKSGSGTELALPADPRRGGQLVSLPPGAGEVLESVDVVFPVLHGPYGEDGTIQGLLELAG 135 VKSGSGTELALPADPRRGGQLVSLPPGAGEVLESVDVVFPVLHGPYGEDGTIQGLLELAG Sbjct 61 VKSGSGTELALPADPRRGGQLVSLPPGAGEVLESVDVVFPVLHGPYGEDGTIQGLLELAG 120 Query 136 VPYVGAGVLASAVGMDKEFTKKLLAADGLPVGAYAVLRPPRSTLHRQECERLGLPVFVKP 195 VPYVGAGVLASAVGMDKEFTKKLLAADGLPVGAYAVLRPPRSTLHRQECERLGLPVFVKP Sbjct 121 VPYVGAGVLASAVGMDKEFTKKLLAADGLPVGAYAVLRPPRSTLHRQECERLGLPVFVKP 180 Query 196 ARGGSSIGVSRVSSWDQLPAAVARARRHDPKVIVEAAISGRELECGVLEMPDGTLEASTL 255 ARGGSSIGVSRVSSWDQLPAAVARARRHDPKVIVEAAISGRELECGVLEMPDGTLEASTL Sbjct 181 ARGGSSIGVSRVSSWDQLPAAVARARRHDPKVIVEAAISGRELECGVLEMPDGTLEASTL 240 Query 256 GEIRVAGVRGREDSFYDFATKYLDDAAELDVPAKVDDQVAEAIRQLAIRAFAAIDCRGLA 315 GEIRVAGVRGREDSFYDFATKYLDDAAELDVPAKVDDQVAEAIRQLAIRAFAAIDCRGLA Sbjct 241 GEIRVAGVRGREDSFYDFATKYLDDAAELDVPAKVDDQVAEAIRQLAIRAFAAIDCRGLA 300 Query 316 RVDFFLTDDGPVINEINTMPGFTTISMYPRMWAASGVDYPTLLATMIETTLARGVGLH 373 RVDFFLTDDGPVINEINTMPGFTTISMYPRMWAASGVDYPTLLATMIETTLARGVGLH Sbjct 301 RVDFFLTDDGPVINEINTMPGFTTISMYPRMWAASGVDYPTLLATMIETTLARGVGLH 358 >gi|253797926|ref|YP_003030927.1| D-alanine-D-alanine ligase ddlA [Mycobacterium tuberculosis KZN 1435] gi|253319429|gb|ACT24032.1| D-alanine-D-alanine ligase ddlA [Mycobacterium tuberculosis KZN 1435] Length=358 Score = 715 bits (1845), Expect = 0.0, Method: Compositional matrix adjust. Identities = 356/358 (99%), Positives = 357/358 (99%), Gaps = 0/358 (0%) Query 16 VFGGRSNEHAISCVSAGSILRNLDSRRFDVIAVGITPAGSWVLTDANPDALTITNRELPQ 75 +FGGRSNEHAISCVSAGSILRNLDSRRFDVIAVGITPAGSWVLTDANPDALTITNRELPQ Sbjct 1 MFGGRSNEHAISCVSAGSILRNLDSRRFDVIAVGITPAGSWVLTDANPDALTITNRELPQ 60 Query 76 VKSGSGTELALPADPRRGGQLVSLPPGAGEVLESVDVVFPVLHGPYGEDGTIQGLLELAG 135 VKSGSGTELALPADPRRGGQLVSLPPGAGEVLESVDVVFPVLHGPYGEDGTIQGLLELAG Sbjct 61 VKSGSGTELALPADPRRGGQLVSLPPGAGEVLESVDVVFPVLHGPYGEDGTIQGLLELAG 120 Query 136 VPYVGAGVLASAVGMDKEFTKKLLAADGLPVGAYAVLRPPRSTLHRQECERLGLPVFVKP 195 VPYVGAGVLASAVGMDKEFTKKLLAADGLPVGAYAVLRPPRSTLHRQECERLGLPVFVKP Sbjct 121 VPYVGAGVLASAVGMDKEFTKKLLAADGLPVGAYAVLRPPRSTLHRQECERLGLPVFVKP 180 Query 196 ARGGSSIGVSRVSSWDQLPAAVARARRHDPKVIVEAAISGRELECGVLEMPDGTLEASTL 255 ARGGSSIGVSRVSSWDQLPAAVARARRHDPKVIVEAAISGRELECGVLEMPDGTLEASTL Sbjct 181 ARGGSSIGVSRVSSWDQLPAAVARARRHDPKVIVEAAISGRELECGVLEMPDGTLEASTL 240 Query 256 GEIRVAGVRGREDSFYDFATKYLDDAAELDVPAKVDDQVAEAIRQLAIRAFAAIDCRGLA 315 GEIRVAGVRGREDSFYDFATKYLDDAAELDVPAKVDDQVAEAIRQLAIRAFAAIDCRGLA Sbjct 241 GEIRVAGVRGREDSFYDFATKYLDDAAELDVPAKVDDQVAEAIRQLAIRAFAAIDCRGLA 300 Query 316 RVDFFLTDDGPVINEINTMPGFTTISMYPRMWAASGVDYPTLLATMIETTLARGVGLH 373 RVDFFLTDDGPVINEINTMPGFTTISMYPRMWAASGVDYPTLLATMIET LARGVGLH Sbjct 301 RVDFFLTDDGPVINEINTMPGFTTISMYPRMWAASGVDYPTLLATMIETALARGVGLH 358 >gi|289575688|ref|ZP_06455915.1| D-alanyl-alanine synthetase A [Mycobacterium tuberculosis K85] gi|289540119|gb|EFD44697.1| D-alanyl-alanine synthetase A [Mycobacterium tuberculosis K85] Length=364 Score = 707 bits (1826), Expect = 0.0, Method: Compositional matrix adjust. Identities = 356/364 (98%), Positives = 357/364 (99%), Gaps = 6/364 (1%) Query 16 VFGGRSNEHAISCVSAGSILRNLDSRRFDVIAVGITPAGSWVLTDANPDALTITNRELPQ 75 +FGGRSNEHAISCVSAGSILRNLDSRRFDVIAVGITPAGSWVLTDANPDALTITNRELPQ Sbjct 1 MFGGRSNEHAISCVSAGSILRNLDSRRFDVIAVGITPAGSWVLTDANPDALTITNRELPQ 60 Query 76 VKSGSGTELALPADPRRGGQLVSLPPGAGEVLESVDVVFPVLHGPYGEDGTIQGLLELAG 135 VKSGSGTELALPADPRRGGQLVSLPPGAGEVLESVDVVFPVLHGPYGEDGTIQGLLELAG Sbjct 61 VKSGSGTELALPADPRRGGQLVSLPPGAGEVLESVDVVFPVLHGPYGEDGTIQGLLELAG 120 Query 136 VPYVGAGVLASAVGMDKEFTKKLLAADGLPVGAYAVLRPPRSTLHRQECERLGLPVFVKP 195 VPYVGAGVLASAVGMDKEFTKKLLAADGLPVGAYAVLRPPRSTLHRQECERLGLPVFVKP Sbjct 121 VPYVGAGVLASAVGMDKEFTKKLLAADGLPVGAYAVLRPPRSTLHRQECERLGLPVFVKP 180 Query 196 ARGGSSIGVSRVSSWDQLPAAVARARRHDPKVIVEAAISGRELECGVLEMPDGTLEASTL 255 ARGGSSIGVSRVSSWDQLPAAVARARRHDPKVIVEAAISGRELECGVLEMPDGTLEASTL Sbjct 181 ARGGSSIGVSRVSSWDQLPAAVARARRHDPKVIVEAAISGRELECGVLEMPDGTLEASTL 240 Query 256 GEIRVAGVRGREDSFYDFATKYLDDAAELDVPAKVDDQVAEAIRQLAIRAFAAIDCRGLA 315 GEIRVAGVRGREDSFYDFATKYLDDAAELDVPAKVDDQVAEAIRQLAIRAFAAIDCRGLA Sbjct 241 GEIRVAGVRGREDSFYDFATKYLDDAAELDVPAKVDDQVAEAIRQLAIRAFAAIDCRGLA 300 Query 316 RVDFFLTD------DGPVINEINTMPGFTTISMYPRMWAASGVDYPTLLATMIETTLARG 369 RVDFFLTD DGPVINEINTMPGFTTISMYPRMWAASGVDYPTLLATMIET LARG Sbjct 301 RVDFFLTDDGPVINDGPVINEINTMPGFTTISMYPRMWAASGVDYPTLLATMIETALARG 360 Query 370 VGLH 373 VGLH Sbjct 361 VGLH 364 >gi|289746785|ref|ZP_06506163.1| D-alanyl-alanine synthetase A [Mycobacterium tuberculosis 02_1987] gi|289687313|gb|EFD54801.1| D-alanyl-alanine synthetase A [Mycobacterium tuberculosis 02_1987] Length=363 Score = 667 bits (1720), Expect = 0.0, Method: Compositional matrix adjust. Identities = 335/340 (99%), Positives = 336/340 (99%), Gaps = 0/340 (0%) Query 1 VSANDRRDRRVRVAVVFGGRSNEHAISCVSAGSILRNLDSRRFDVIAVGITPAGSWVLTD 60 VSANDRRDRRVRVAVVFGGRSNEHAISCVSAGSILRNLDSRRFDVIAVGITPAGSWVLTD Sbjct 4 VSANDRRDRRVRVAVVFGGRSNEHAISCVSAGSILRNLDSRRFDVIAVGITPAGSWVLTD 63 Query 61 ANPDALTITNRELPQVKSGSGTELALPADPRRGGQLVSLPPGAGEVLESVDVVFPVLHGP 120 ANPDALTITNRELPQVKSGSGTELALPADPRRGGQLVSLPPGAGEVLESVDVVFPVLHGP Sbjct 64 ANPDALTITNRELPQVKSGSGTELALPADPRRGGQLVSLPPGAGEVLESVDVVFPVLHGP 123 Query 121 YGEDGTIQGLLELAGVPYVGAGVLASAVGMDKEFTKKLLAADGLPVGAYAVLRPPRSTLH 180 YGEDGTIQGLLELAGVPYVGAGVLASAVGMDKEFTKKLLAADGLPVGAYAVLRPPRSTLH Sbjct 124 YGEDGTIQGLLELAGVPYVGAGVLASAVGMDKEFTKKLLAADGLPVGAYAVLRPPRSTLH 183 Query 181 RQECERLGLPVFVKPARGGSSIGVSRVSSWDQLPAAVARARRHDPKVIVEAAISGRELEC 240 RQECERLGLPVFVKPARGGSSIGVSRVSSWDQLPAAVARARRHDPKVIVEAAISGRELEC Sbjct 184 RQECERLGLPVFVKPARGGSSIGVSRVSSWDQLPAAVARARRHDPKVIVEAAISGRELEC 243 Query 241 GVLEMPDGTLEASTLGEIRVAGVRGREDSFYDFATKYLDDAAELDVPAKVDDQVAEAIRQ 300 GVLEMPDGTLEASTLGEIRVAGVRGREDSFYDFATKYLDDAAELDVPAKVDDQVAEAIRQ Sbjct 244 GVLEMPDGTLEASTLGEIRVAGVRGREDSFYDFATKYLDDAAELDVPAKVDDQVAEAIRQ 303 Query 301 LAIRAFAAIDCRGLARVDFFLTDDGPVINEINTMPGFTTI 340 LAIRAFAAIDCRGLARVDFFLTDDGPVINEINTMP + Sbjct 304 LAIRAFAAIDCRGLARVDFFLTDDGPVINEINTMPAIHHV 343 >gi|183981746|ref|YP_001850037.1| d-alanine--D-alanine ligase DdlA [Mycobacterium marinum M] gi|183175072|gb|ACC40182.1| d-alanine--D-alanine ligase DdlA [Mycobacterium marinum M] Length=373 Score = 640 bits (1652), Expect = 0.0, Method: Compositional matrix adjust. Identities = 317/373 (85%), Positives = 342/373 (92%), Gaps = 0/373 (0%) Query 1 VSANDRRDRRVRVAVVFGGRSNEHAISCVSAGSILRNLDSRRFDVIAVGITPAGSWVLTD 60 +S + RR R+RVAVVFGGRSNEHAISCVSAGSILRNLD RRF+VIA+GITP GSWVLTD Sbjct 1 MSGSSRRGERLRVAVVFGGRSNEHAISCVSAGSILRNLDPRRFEVIAIGITPQGSWVLTD 60 Query 61 ANPDALTITNRELPQVKSGSGTELALPADPRRGGQLVSLPPGAGEVLESVDVVFPVLHGP 120 NPDAL IT+R LP+V S SGTELALPADPR GGQLVSLPPGAGEVL SVDVVFPVLHGP Sbjct 61 GNPDALAITDRRLPEVSSQSGTELALPADPRWGGQLVSLPPGAGEVLASVDVVFPVLHGP 120 Query 121 YGEDGTIQGLLELAGVPYVGAGVLASAVGMDKEFTKKLLAADGLPVGAYAVLRPPRSTLH 180 YGEDGTIQGLLELAGVPYVGAGVLASA GMDKEFTKKL +A GLP+G +AVLRP R +L Sbjct 121 YGEDGTIQGLLELAGVPYVGAGVLASAAGMDKEFTKKLWSAAGLPIGPHAVLRPSRQSLD 180 Query 181 RQECERLGLPVFVKPARGGSSIGVSRVSSWDQLPAAVARARRHDPKVIVEAAISGRELEC 240 R+E +RLGLP +VKPARGGSSIGVSRVSS+D+LPAA+A ARRHDPKVIVEAAI+GRELEC Sbjct 181 REELQRLGLPAYVKPARGGSSIGVSRVSSFDELPAAIAAARRHDPKVIVEAAINGRELEC 240 Query 241 GVLEMPDGTLEASTLGEIRVAGVRGREDSFYDFATKYLDDAAELDVPAKVDDQVAEAIRQ 300 GVLE PDG LEASTLGEIRVAGVRGRED FYDF TKYLDDAAELDVPAKV+D VA+A+RQ Sbjct 241 GVLEFPDGRLEASTLGEIRVAGVRGREDGFYDFETKYLDDAAELDVPAKVEDDVADAVRQ 300 Query 301 LAIRAFAAIDCRGLARVDFFLTDDGPVINEINTMPGFTTISMYPRMWAASGVDYPTLLAT 360 LAIRAF AIDC+GLARVDFFLTDDGPVINEINTMPGFTTISMYPRMWAASGVDYPTLLAT Sbjct 301 LAIRAFEAIDCQGLARVDFFLTDDGPVINEINTMPGFTTISMYPRMWAASGVDYPTLLAT 360 Query 361 MIETTLARGVGLH 373 M+ET L+RG+GL Sbjct 361 MVETALSRGIGLR 373 >gi|118617561|ref|YP_905893.1| D-alanyl-alanine synthetase A [Mycobacterium ulcerans Agy99] gi|166198494|sp|A0PQ03.1|DDL_MYCUA RecName: Full=D-alanine--D-alanine ligase; AltName: Full=D-Ala-D-Ala ligase; AltName: Full=D-alanylalanine synthetase gi|118569671|gb|ABL04422.1| d-alanine--D-alanine ligase DdlA [Mycobacterium ulcerans Agy99] Length=373 Score = 637 bits (1644), Expect = 0.0, Method: Compositional matrix adjust. Identities = 315/373 (85%), Positives = 341/373 (92%), Gaps = 0/373 (0%) Query 1 VSANDRRDRRVRVAVVFGGRSNEHAISCVSAGSILRNLDSRRFDVIAVGITPAGSWVLTD 60 +S + RR R+RVAVVFGGRSNEHAISCVSAGSILRNLD RRF+VIA+GITP GSWVLTD Sbjct 1 MSGSSRRGERLRVAVVFGGRSNEHAISCVSAGSILRNLDPRRFEVIAIGITPQGSWVLTD 60 Query 61 ANPDALTITNRELPQVKSGSGTELALPADPRRGGQLVSLPPGAGEVLESVDVVFPVLHGP 120 NPDAL IT+R LP+V S SGTELALPADPR GGQLVSLPPGAGEVL SVDVVFPVLHGP Sbjct 61 GNPDALAITDRRLPEVSSQSGTELALPADPRWGGQLVSLPPGAGEVLASVDVVFPVLHGP 120 Query 121 YGEDGTIQGLLELAGVPYVGAGVLASAVGMDKEFTKKLLAADGLPVGAYAVLRPPRSTLH 180 YGEDGTIQGLLELAGVPYVGAGVLASA GMDKEFTKKL +A GLP+G +AVLRP R +L Sbjct 121 YGEDGTIQGLLELAGVPYVGAGVLASAAGMDKEFTKKLWSAAGLPIGPHAVLRPSRQSLD 180 Query 181 RQECERLGLPVFVKPARGGSSIGVSRVSSWDQLPAAVARARRHDPKVIVEAAISGRELEC 240 R+E +RLGLP +VKPARGGSSIGVSRVSS+D+LPAA+A ARRHDPKVIVEAAI+GRELEC Sbjct 181 REELQRLGLPAYVKPARGGSSIGVSRVSSFDELPAAIAAARRHDPKVIVEAAINGRELEC 240 Query 241 GVLEMPDGTLEASTLGEIRVAGVRGREDSFYDFATKYLDDAAELDVPAKVDDQVAEAIRQ 300 GVLE PDG LEASTLGEIRVAGVRGRED FYDF TKYLDDAAELDVPAKV+D VA+A+RQ Sbjct 241 GVLEFPDGRLEASTLGEIRVAGVRGREDGFYDFETKYLDDAAELDVPAKVEDDVADAVRQ 300 Query 301 LAIRAFAAIDCRGLARVDFFLTDDGPVINEINTMPGFTTISMYPRMWAASGVDYPTLLAT 360 LAIRAF AIDC+GLARVDFFLTDDGPVINE+NTMPGFTTISMYPRMW ASGVDYPTLLAT Sbjct 301 LAIRAFEAIDCQGLARVDFFLTDDGPVINELNTMPGFTTISMYPRMWVASGVDYPTLLAT 360 Query 361 MIETTLARGVGLH 373 M+ET L+RG+GL Sbjct 361 MVETALSRGIGLR 373 >gi|254819105|ref|ZP_05224106.1| D-alanyl-alanine synthetase A [Mycobacterium intracellulare ATCC 13950] Length=381 Score = 637 bits (1643), Expect = 0.0, Method: Compositional matrix adjust. Identities = 314/364 (87%), Positives = 337/364 (93%), Gaps = 0/364 (0%) Query 10 RVRVAVVFGGRSNEHAISCVSAGSILRNLDSRRFDVIAVGITPAGSWVLTDANPDALTIT 69 R RVAVVFGGRSNEHAISCVSAGSILRNLD RF+V+A+GITP GSWVLTD +P AL IT Sbjct 18 RARVAVVFGGRSNEHAISCVSAGSILRNLDPERFEVVAIGITPEGSWVLTDGDPAALAIT 77 Query 70 NRELPQVKSGSGTELALPADPRRGGQLVSLPPGAGEVLESVDVVFPVLHGPYGEDGTIQG 129 +R LP+V + SGTELAL ADPRRGGQLV+LPPGAGEVL SVDVVFPVLHGPYGEDGTIQG Sbjct 78 DRRLPEVTAESGTELALSADPRRGGQLVALPPGAGEVLASVDVVFPVLHGPYGEDGTIQG 137 Query 130 LLELAGVPYVGAGVLASAVGMDKEFTKKLLAADGLPVGAYAVLRPPRSTLHRQECERLGL 189 LLELAGVPYVGAGVLASA GMDKEFTKKL AA+GLPVG YAVLRP R+ L +EC+RLGL Sbjct 138 LLELAGVPYVGAGVLASAAGMDKEFTKKLFAAEGLPVGDYAVLRPSRARLRPEECQRLGL 197 Query 190 PVFVKPARGGSSIGVSRVSSWDQLPAAVARARRHDPKVIVEAAISGRELECGVLEMPDGT 249 PVFVKPARGGSSIGVSRV+SWDQL AAVA ARRHDPKVIVEAAI GRELECGVLEMPDGT Sbjct 198 PVFVKPARGGSSIGVSRVASWDQLDAAVAAARRHDPKVIVEAAIVGRELECGVLEMPDGT 257 Query 250 LEASTLGEIRVAGVRGREDSFYDFATKYLDDAAELDVPAKVDDQVAEAIRQLAIRAFAAI 309 +EAS LGEIRVAGVRGREDSFYDFATKYLDDAAELDVPAKVDD++A+ +RQLA+RAF AI Sbjct 258 VEASALGEIRVAGVRGREDSFYDFATKYLDDAAELDVPAKVDDEIADTVRQLAVRAFKAI 317 Query 310 DCRGLARVDFFLTDDGPVINEINTMPGFTTISMYPRMWAASGVDYPTLLATMIETTLARG 369 DC+GLARVDFFLT+DGPV+NEINTMPGFTTISMYPRMWAASGVDYPTLLATM+ET LARG Sbjct 318 DCQGLARVDFFLTEDGPVLNEINTMPGFTTISMYPRMWAASGVDYPTLLATMVETALARG 377 Query 370 VGLH 373 VGL Sbjct 378 VGLR 381 >gi|342858192|ref|ZP_08714847.1| D-alanyl-alanine synthetase A [Mycobacterium colombiense CECT 3035] gi|342133896|gb|EGT87076.1| D-alanyl-alanine synthetase A [Mycobacterium colombiense CECT 3035] Length=381 Score = 634 bits (1636), Expect = 6e-180, Method: Compositional matrix adjust. Identities = 313/364 (86%), Positives = 335/364 (93%), Gaps = 0/364 (0%) Query 10 RVRVAVVFGGRSNEHAISCVSAGSILRNLDSRRFDVIAVGITPAGSWVLTDANPDALTIT 69 RVRVAVVFGGRSNEHAISCVSAGSILRNLD RFDV+A+GITP GSWVLTD +P AL IT Sbjct 18 RVRVAVVFGGRSNEHAISCVSAGSILRNLDPERFDVVAIGITPQGSWVLTDGDPAALAIT 77 Query 70 NRELPQVKSGSGTELALPADPRRGGQLVSLPPGAGEVLESVDVVFPVLHGPYGEDGTIQG 129 +R+LP+V S SGTELAL ADPRRGG+LVSL PGA EVL SVDV+FPVLHGPYGEDGTIQG Sbjct 78 DRQLPEVTSDSGTELALTADPRRGGELVSLAPGASEVLASVDVIFPVLHGPYGEDGTIQG 137 Query 130 LLELAGVPYVGAGVLASAVGMDKEFTKKLLAADGLPVGAYAVLRPPRSTLHRQECERLGL 189 LLELAGVPYVGAGVLASA GMDKEFTKKL A+GLPVG YAVLRP RS L +ECERLGL Sbjct 138 LLELAGVPYVGAGVLASAAGMDKEFTKKLFTAEGLPVGDYAVLRPSRSRLAPEECERLGL 197 Query 190 PVFVKPARGGSSIGVSRVSSWDQLPAAVARARRHDPKVIVEAAISGRELECGVLEMPDGT 249 PVFVKPARGGSSIGVSRVSSWDQL A+A ARRHDPKVIVEAAI GRELECGVLEMPDGT Sbjct 198 PVFVKPARGGSSIGVSRVSSWDQLDGAIAAARRHDPKVIVEAAIVGRELECGVLEMPDGT 257 Query 250 LEASTLGEIRVAGVRGREDSFYDFATKYLDDAAELDVPAKVDDQVAEAIRQLAIRAFAAI 309 +EASTLGEIRVAGVRGREDSFYDF+TKYLDDAAELDVPAKVDD++A+ +RQLA+RAF AI Sbjct 258 VEASTLGEIRVAGVRGREDSFYDFSTKYLDDAAELDVPAKVDDEIADTVRQLAVRAFRAI 317 Query 310 DCRGLARVDFFLTDDGPVINEINTMPGFTTISMYPRMWAASGVDYPTLLATMIETTLARG 369 DC+GLARVDFFLT+DGPV+NEINTMPGFTTISMYPRMWAASGVDY TLLATM+ET LARG Sbjct 318 DCQGLARVDFFLTEDGPVLNEINTMPGFTTISMYPRMWAASGVDYATLLATMVETALARG 377 Query 370 VGLH 373 VGL Sbjct 378 VGLR 381 >gi|41409117|ref|NP_961953.1| D-alanyl-alanine synthetase A [Mycobacterium avium subsp. paratuberculosis K-10] gi|254776254|ref|ZP_05217770.1| D-alanyl-alanine synthetase A [Mycobacterium avium subsp. avium ATCC 25291] gi|81413470|sp|Q73VJ4.1|DDL_MYCPA RecName: Full=D-alanine--D-alanine ligase; AltName: Full=D-Ala-D-Ala ligase; AltName: Full=D-alanylalanine synthetase gi|41397937|gb|AAS05567.1| DdlA [Mycobacterium avium subsp. paratuberculosis K-10] gi|336459123|gb|EGO38071.1| D-alanine--D-alanine ligase [Mycobacterium avium subsp. paratuberculosis S397] Length=369 Score = 631 bits (1628), Expect = 5e-179, Method: Compositional matrix adjust. Identities = 309/365 (85%), Positives = 338/365 (93%), Gaps = 0/365 (0%) Query 9 RRVRVAVVFGGRSNEHAISCVSAGSILRNLDSRRFDVIAVGITPAGSWVLTDANPDALTI 68 +RVRVAVVFGGRSNEHAISCVSAGSILRNLD RRF+V+A+GITP GSWVLTD +P AL I Sbjct 5 QRVRVAVVFGGRSNEHAISCVSAGSILRNLDPRRFEVVAIGITPQGSWVLTDGDPAALAI 64 Query 69 TNRELPQVKSGSGTELALPADPRRGGQLVSLPPGAGEVLESVDVVFPVLHGPYGEDGTIQ 128 ++R+LP+V S SGTELALPADP R GQLVSLPPGA EVL SVDVVFPVLHGPYGEDGTIQ Sbjct 65 SDRQLPEVTSASGTELALPADPGRSGQLVSLPPGASEVLASVDVVFPVLHGPYGEDGTIQ 124 Query 129 GLLELAGVPYVGAGVLASAVGMDKEFTKKLLAADGLPVGAYAVLRPPRSTLHRQECERLG 188 GLLELAGVPYVGAGV ASA GMDKEFTKKL AA+GLP+G YAVLRP +STL Q+ ERLG Sbjct 125 GLLELAGVPYVGAGVFASAAGMDKEFTKKLFAAEGLPIGDYAVLRPSQSTLSLQDRERLG 184 Query 189 LPVFVKPARGGSSIGVSRVSSWDQLPAAVARARRHDPKVIVEAAISGRELECGVLEMPDG 248 LPVFVKPARGGSSIGVSRVSSWD+L AAVA AR HDPKVIVEAAI+GRELECGVLEMPDG Sbjct 185 LPVFVKPARGGSSIGVSRVSSWDELDAAVAAARDHDPKVIVEAAIAGRELECGVLEMPDG 244 Query 249 TLEASTLGEIRVAGVRGREDSFYDFATKYLDDAAELDVPAKVDDQVAEAIRQLAIRAFAA 308 T++AST+GEIRVAGVRGREDSFYDFATKYLDD AELDVPAKVDD++A+A+R+LAIRAF A Sbjct 245 TVQASTVGEIRVAGVRGREDSFYDFATKYLDDTAELDVPAKVDDEIADAVRELAIRAFKA 304 Query 309 IDCRGLARVDFFLTDDGPVINEINTMPGFTTISMYPRMWAASGVDYPTLLATMIETTLAR 368 +DC+GLARVDFFLT+ GPV+NEINTMPGFTTISMYPRMWAASGVDYP+LLATM+ET LAR Sbjct 305 VDCQGLARVDFFLTETGPVLNEINTMPGFTTISMYPRMWAASGVDYPSLLATMVETALAR 364 Query 369 GVGLH 373 GVGL Sbjct 365 GVGLR 369 >gi|118464178|ref|YP_883000.1| D-alanyl-alanine synthetase A [Mycobacterium avium 104] gi|189083043|sp|A0QJB2.1|DDL_MYCA1 RecName: Full=D-alanine--D-alanine ligase; AltName: Full=D-Ala-D-Ala ligase; AltName: Full=D-alanylalanine synthetase gi|118165465|gb|ABK66362.1| D-alanine--D-alanine ligase [Mycobacterium avium 104] Length=369 Score = 629 bits (1623), Expect = 2e-178, Method: Compositional matrix adjust. Identities = 308/365 (85%), Positives = 337/365 (93%), Gaps = 0/365 (0%) Query 9 RRVRVAVVFGGRSNEHAISCVSAGSILRNLDSRRFDVIAVGITPAGSWVLTDANPDALTI 68 +RVRVAVVFGGRSNEHAISCVSAGSILRNLD RRF+V+A+GITP GSWVLTD +P AL I Sbjct 5 QRVRVAVVFGGRSNEHAISCVSAGSILRNLDPRRFEVVAIGITPQGSWVLTDGDPAALAI 64 Query 69 TNRELPQVKSGSGTELALPADPRRGGQLVSLPPGAGEVLESVDVVFPVLHGPYGEDGTIQ 128 ++R+LP+V S SGTELALPADP R GQLVSLPPGA EVL SVDVVFPVLHGPYGEDGTIQ Sbjct 65 SDRQLPEVTSASGTELALPADPGRSGQLVSLPPGASEVLASVDVVFPVLHGPYGEDGTIQ 124 Query 129 GLLELAGVPYVGAGVLASAVGMDKEFTKKLLAADGLPVGAYAVLRPPRSTLHRQECERLG 188 GLLELAGVPYVGAGV ASA GMDKEFTKKL AA+GLP+G YAVLRP +STL Q+ ERLG Sbjct 125 GLLELAGVPYVGAGVFASAAGMDKEFTKKLFAAEGLPIGDYAVLRPSQSTLSLQDRERLG 184 Query 189 LPVFVKPARGGSSIGVSRVSSWDQLPAAVARARRHDPKVIVEAAISGRELECGVLEMPDG 248 LPVFVKPARGGSSIGVSRVSSWD+L AAVA AR HDPKVIVEAAI+GRELECGVLEMPDG Sbjct 185 LPVFVKPARGGSSIGVSRVSSWDELDAAVAAARDHDPKVIVEAAIAGRELECGVLEMPDG 244 Query 249 TLEASTLGEIRVAGVRGREDSFYDFATKYLDDAAELDVPAKVDDQVAEAIRQLAIRAFAA 308 T++AST+GEIRVAGVRGREDSFYDFATKYLDD AELDVPAKVDD++A+A+R+LAIRAF A Sbjct 245 TVQASTVGEIRVAGVRGREDSFYDFATKYLDDTAELDVPAKVDDEIADAVRELAIRAFKA 304 Query 309 IDCRGLARVDFFLTDDGPVINEINTMPGFTTISMYPRMWAASGVDYPTLLATMIETTLAR 368 +DC+GLARVDFFLT+ GPV+NEINTMPGFTTISMYPRMWAASGVDYP+LLATM+ET L R Sbjct 305 VDCQGLARVDFFLTETGPVLNEINTMPGFTTISMYPRMWAASGVDYPSLLATMVETALTR 364 Query 369 GVGLH 373 GVGL Sbjct 365 GVGLR 369 >gi|240168958|ref|ZP_04747617.1| D-alanyl-alanine synthetase A [Mycobacterium kansasii ATCC 12478] Length=370 Score = 620 bits (1599), Expect = 1e-175, Method: Compositional matrix adjust. Identities = 318/365 (88%), Positives = 338/365 (93%), Gaps = 0/365 (0%) Query 8 DRRVRVAVVFGGRSNEHAISCVSAGSILRNLDSRRFDVIAVGITPAGSWVLTDANPDALT 67 DRR RVAVVFGGRSNEHAISCVSAGSILRNLD +RF+VIA+GITP GSWVLTD NPDAL Sbjct 5 DRRARVAVVFGGRSNEHAISCVSAGSILRNLDPQRFEVIAIGITPQGSWVLTDGNPDALA 64 Query 68 ITNRELPQVKSGSGTELALPADPRRGGQLVSLPPGAGEVLESVDVVFPVLHGPYGEDGTI 127 ITNR+LP V S SGT LALPADP+ GG+LVSLPPGAGEVL SVDVVFPVLHGPYGEDGTI Sbjct 65 ITNRQLPAVSSESGTLLALPADPQWGGRLVSLPPGAGEVLASVDVVFPVLHGPYGEDGTI 124 Query 128 QGLLELAGVPYVGAGVLASAVGMDKEFTKKLLAADGLPVGAYAVLRPPRSTLHRQECERL 187 QGLLELAGVPYVGAGVLASA GMDKEFTKKLL ADGLPVG +AVLRP R L ECERL Sbjct 125 QGLLELAGVPYVGAGVLASAAGMDKEFTKKLLTADGLPVGPHAVLRPSRPALSLDECERL 184 Query 188 GLPVFVKPARGGSSIGVSRVSSWDQLPAAVARARRHDPKVIVEAAISGRELECGVLEMPD 247 GLP +VKPARGGSSIGVSRVSSWD+LPAAVA ARRHDPKVIVEAA++GRELECGVLE PD Sbjct 185 GLPAYVKPARGGSSIGVSRVSSWDELPAAVAEARRHDPKVIVEAAVNGRELECGVLEFPD 244 Query 248 GTLEASTLGEIRVAGVRGREDSFYDFATKYLDDAAELDVPAKVDDQVAEAIRQLAIRAFA 307 GT++ASTLGEIRVAGVRGRED+FYDFATKYLDDAAELDVPAKVDD VA+A+R LAIRAF Sbjct 245 GTVQASTLGEIRVAGVRGREDAFYDFATKYLDDAAELDVPAKVDDDVADAVRDLAIRAFH 304 Query 308 AIDCRGLARVDFFLTDDGPVINEINTMPGFTTISMYPRMWAASGVDYPTLLATMIETTLA 367 AIDC+GLARVDFFLT++GPVINEINTMPGFTTISMYPRMWAASGVDYPTLLATM+ET LA Sbjct 305 AIDCQGLARVDFFLTEEGPVINEINTMPGFTTISMYPRMWAASGVDYPTLLATMVETALA 364 Query 368 RGVGL 372 RGVGL Sbjct 365 RGVGL 369 >gi|15827889|ref|NP_302152.1| D-alanyl-alanine synthetase A [Mycobacterium leprae TN] gi|221230366|ref|YP_002503782.1| D-alanyl-alanine synthetase A [Mycobacterium leprae Br4923] gi|18202756|sp|Q9CBS0.1|DDL_MYCLE RecName: Full=D-alanine--D-alanine ligase; AltName: Full=D-Ala-D-Ala ligase; AltName: Full=D-alanylalanine synthetase gi|13093442|emb|CAC30631.1| D-alanine-D-alanine ligase A [Mycobacterium leprae] gi|219933473|emb|CAR71773.1| D-alanine-D-alanine ligase A [Mycobacterium leprae Br4923] Length=384 Score = 608 bits (1568), Expect = 4e-172, Method: Compositional matrix adjust. Identities = 300/367 (82%), Positives = 325/367 (89%), Gaps = 4/367 (1%) Query 10 RVRVAVVFGGRSNEHAISCVSAGSILRNLDSRRFDVIAVGITPAGSWVLTDANPDALTIT 69 RVRVAVVFGGRSNEHA+SC+SAGSILRNLD +RFDV+AVGITP G+W+LTD NPDAL I Sbjct 17 RVRVAVVFGGRSNEHAVSCLSAGSILRNLDRQRFDVVAVGITPEGTWMLTDPNPDALAIA 76 Query 70 NRELPQVKSGSGTELALPADPRRGGQLVSLPPGAG----EVLESVDVVFPVLHGPYGEDG 125 NR+LP V SG EL LPADPRR GQLVSL GAG EVL SVDVVFPVLHGPYGEDG Sbjct 77 NRQLPAVSCESGIELTLPADPRRSGQLVSLSHGAGLGAGEVLTSVDVVFPVLHGPYGEDG 136 Query 126 TIQGLLELAGVPYVGAGVLASAVGMDKEFTKKLLAADGLPVGAYAVLRPPRSTLHRQECE 185 TIQGLLELA VPYVGAGVLASA GMDKEFTKKL AA+GLP+ AY VLRP R TLHRQECE Sbjct 137 TIQGLLELARVPYVGAGVLASAAGMDKEFTKKLFAAEGLPLSAYTVLRPLRPTLHRQECE 196 Query 186 RLGLPVFVKPARGGSSIGVSRVSSWDQLPAAVARARRHDPKVIVEAAISGRELECGVLEM 245 RL LPVFVKPARGGSSIG+SRVSSW QLP+A+A ARRHDPKVIVEAA++GRELECGVLEM Sbjct 197 RLSLPVFVKPARGGSSIGISRVSSWGQLPSAIAYARRHDPKVIVEAAVNGRELECGVLEM 256 Query 246 PDGTLEASTLGEIRVAGVRGREDSFYDFATKYLDDAAELDVPAKVDDQVAEAIRQLAIRA 305 PDGT+ AS +GEIRVAGV G EDSFYDF TKYLDDAAELDVPAKVDD VA+ +RQLAI+A Sbjct 257 PDGTVAASAVGEIRVAGVSGSEDSFYDFTTKYLDDAAELDVPAKVDDDVADEVRQLAIQA 316 Query 306 FAAIDCRGLARVDFFLTDDGPVINEINTMPGFTTISMYPRMWAASGVDYPTLLATMIETT 365 F AIDC+GLARVDFFLTDDGPVINEINTMPGFT SMYP++WA S VDYPTLLATM++T Sbjct 317 FRAIDCQGLARVDFFLTDDGPVINEINTMPGFTMTSMYPKLWAVSSVDYPTLLATMVDTA 376 Query 366 LARGVGL 372 LARGVG+ Sbjct 377 LARGVGM 383 >gi|296171291|ref|ZP_06852695.1| D-alanine-D-alanine ligase [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295894259|gb|EFG74016.1| D-alanine-D-alanine ligase [Mycobacterium parascrofulaceum ATCC BAA-614] Length=363 Score = 605 bits (1561), Expect = 3e-171, Method: Compositional matrix adjust. Identities = 314/363 (87%), Positives = 334/363 (93%), Gaps = 0/363 (0%) Query 11 VRVAVVFGGRSNEHAISCVSAGSILRNLDSRRFDVIAVGITPAGSWVLTDANPDALTITN 70 +RVAVVFGGRSNEHAISCVSAGSILRNLD RF+V+A+GITP GSWVLTD +PDAL I+N Sbjct 1 MRVAVVFGGRSNEHAISCVSAGSILRNLDPERFEVVAIGITPQGSWVLTDGDPDALAISN 60 Query 71 RELPQVKSGSGTELALPADPRRGGQLVSLPPGAGEVLESVDVVFPVLHGPYGEDGTIQGL 130 R+LP+V + SGTELALPADP R GQLVSL GAGEVL SVDVVFPVLHGPYGEDGTIQGL Sbjct 61 RQLPEVTAQSGTELALPADPLRSGQLVSLSTGAGEVLASVDVVFPVLHGPYGEDGTIQGL 120 Query 131 LELAGVPYVGAGVLASAVGMDKEFTKKLLAADGLPVGAYAVLRPPRSTLHRQECERLGLP 190 LELAGVPYVGAGVLASA GMDKEFTKKL A+GLPVG YAVLRP RSTL ECERLGLP Sbjct 121 LELAGVPYVGAGVLASAAGMDKEFTKKLFVAEGLPVGDYAVLRPSRSTLRPDECERLGLP 180 Query 191 VFVKPARGGSSIGVSRVSSWDQLPAAVARARRHDPKVIVEAAISGRELECGVLEMPDGTL 250 VFVKPARGGSSIGV+RVSSWD L AAVA ARRHDPKVIVEAAI+GRE+ECGVLEMPDG++ Sbjct 181 VFVKPARGGSSIGVTRVSSWDDLAAAVAVARRHDPKVIVEAAITGREVECGVLEMPDGSV 240 Query 251 EASTLGEIRVAGVRGREDSFYDFATKYLDDAAELDVPAKVDDQVAEAIRQLAIRAFAAID 310 EASTLGEIRVAGVRGREDSFYDFATKYLDDAAELDVPAKVDD +A+AIR LAIRAF AID Sbjct 241 EASTLGEIRVAGVRGREDSFYDFATKYLDDAAELDVPAKVDDDIADAIRDLAIRAFKAID 300 Query 311 CRGLARVDFFLTDDGPVINEINTMPGFTTISMYPRMWAASGVDYPTLLATMIETTLARGV 370 C+GLARVDFFLTDDGPV+NEINTMPGFTTISMYPRMWAASGVDYPTLLATM+ET LARG Sbjct 301 CQGLARVDFFLTDDGPVLNEINTMPGFTTISMYPRMWAASGVDYPTLLATMVETALARGT 360 Query 371 GLH 373 GL Sbjct 361 GLR 363 >gi|108798897|ref|YP_639094.1| D-alanyl-alanine synthetase A [Mycobacterium sp. MCS] gi|119868012|ref|YP_937964.1| D-alanyl-alanine synthetase A [Mycobacterium sp. KMS] gi|123179010|sp|Q1BAP6.1|DDL_MYCSS RecName: Full=D-alanine--D-alanine ligase; AltName: Full=D-Ala-D-Ala ligase; AltName: Full=D-alanylalanine synthetase gi|167012329|sp|A1UEB6.1|DDL_MYCSK RecName: Full=D-alanine--D-alanine ligase; AltName: Full=D-Ala-D-Ala ligase; AltName: Full=D-alanylalanine synthetase gi|108769316|gb|ABG08038.1| D-alanine--D-alanine ligase [Mycobacterium sp. MCS] gi|119694101|gb|ABL91174.1| D-alanine--D-alanine ligase [Mycobacterium sp. KMS] Length=371 Score = 586 bits (1510), Expect = 2e-165, Method: Compositional matrix adjust. Identities = 294/368 (80%), Positives = 323/368 (88%), Gaps = 1/368 (0%) Query 7 RDRRVRVAVVFGGRSNEHAISCVSAGSILRNLDSRRFDVIAVGITPAGSWVLTDANPDAL 66 R++R RVAVV+GGRS+EHAISCVSAGSILRNLD RFDV+AVGITP GSWVLTD P+ L Sbjct 4 RNQRTRVAVVYGGRSSEHAISCVSAGSILRNLDPERFDVVAVGITPDGSWVLTDGRPETL 63 Query 67 TITNRELPQVKSGSGTELALPADPRRGGQLVSLPPGA-GEVLESVDVVFPVLHGPYGEDG 125 IT+ LP+V + SGT LALPADP R G+LVSL P A GEVL +VDVVFPVLHGPYGEDG Sbjct 64 AITDGRLPEVSAESGTALALPADPGRRGELVSLSPAAAGEVLAAVDVVFPVLHGPYGEDG 123 Query 126 TIQGLLELAGVPYVGAGVLASAVGMDKEFTKKLLAADGLPVGAYAVLRPPRSTLHRQECE 185 TIQGLLELAGVPYVGAGVLASA GMDKEFTKKLL A+GLPVG + VLRP R+ + E E Sbjct 124 TIQGLLELAGVPYVGAGVLASAAGMDKEFTKKLLVAEGLPVGDHVVLRPGRANVTLDERE 183 Query 186 RLGLPVFVKPARGGSSIGVSRVSSWDQLPAAVARARRHDPKVIVEAAISGRELECGVLEM 245 RLGLPVFVKPARGGSSIGVSRVS W +LPAA+ ARRHDPKVIVEA I+GRELECGVLE Sbjct 184 RLGLPVFVKPARGGSSIGVSRVSDWAELPAAIEAARRHDPKVIVEAGIAGRELECGVLEY 243 Query 246 PDGTLEASTLGEIRVAGVRGREDSFYDFATKYLDDAAELDVPAKVDDQVAEAIRQLAIRA 305 PDG ++AST+GEIRVAGVRGRED FYDFATKYLDD AELDVPAKV+D VA+ IR+LAIRA Sbjct 244 PDGRVDASTIGEIRVAGVRGREDGFYDFATKYLDDGAELDVPAKVEDDVADEIRRLAIRA 303 Query 306 FAAIDCRGLARVDFFLTDDGPVINEINTMPGFTTISMYPRMWAASGVDYPTLLATMIETT 365 F AIDC+GLARVDFFLTDDGPV+NEINTMPGFTTISMYPRMWAASGVDYPTLLA M++T Sbjct 304 FRAIDCQGLARVDFFLTDDGPVVNEINTMPGFTTISMYPRMWAASGVDYPTLLAAMVDTA 363 Query 366 LARGVGLH 373 +ARG GL Sbjct 364 VARGTGLR 371 >gi|145224798|ref|YP_001135476.1| D-alanyl-alanine synthetase A [Mycobacterium gilvum PYR-GCK] gi|190359168|sp|A4TE25.1|DDL_MYCGI RecName: Full=D-alanine--D-alanine ligase; AltName: Full=D-Ala-D-Ala ligase; AltName: Full=D-alanylalanine synthetase gi|145217284|gb|ABP46688.1| D-alanine--D-alanine ligase [Mycobacterium gilvum PYR-GCK] Length=367 Score = 585 bits (1509), Expect = 3e-165, Method: Compositional matrix adjust. Identities = 294/364 (81%), Positives = 316/364 (87%), Gaps = 0/364 (0%) Query 10 RVRVAVVFGGRSNEHAISCVSAGSILRNLDSRRFDVIAVGITPAGSWVLTDANPDALTIT 69 R+RVAVV+GGRS+EHAISCVSAGSILRNLD RF+V AVGITP GSWVLT+ P+ L IT Sbjct 4 RIRVAVVYGGRSSEHAISCVSAGSILRNLDPDRFEVTAVGITPEGSWVLTEGRPETLAIT 63 Query 70 NRELPQVKSGSGTELALPADPRRGGQLVSLPPGAGEVLESVDVVFPVLHGPYGEDGTIQG 129 + +LP V SGT L L ADP R GQLVSL AGEVL S DVVFPVLHGPYGEDGTIQG Sbjct 64 DGKLPGVTGDSGTALTLTADPARRGQLVSLGEAAGEVLASADVVFPVLHGPYGEDGTIQG 123 Query 130 LLELAGVPYVGAGVLASAVGMDKEFTKKLLAADGLPVGAYAVLRPPRSTLHRQECERLGL 189 LLELAGVPYVGAGVLASA GMDKEFTKKLLA+ GLPVG + VLR STL Q+ ERLGL Sbjct 124 LLELAGVPYVGAGVLASAAGMDKEFTKKLLASAGLPVGDHVVLRARDSTLSLQDRERLGL 183 Query 190 PVFVKPARGGSSIGVSRVSSWDQLPAAVARARRHDPKVIVEAAISGRELECGVLEMPDGT 249 PVFVKP+RGGSSIGVSRV++WD+LPAA+ ARRHDPKVI+EAA+ GRELECGVLE PDG Sbjct 184 PVFVKPSRGGSSIGVSRVTAWDELPAAIELARRHDPKVIIEAAVPGRELECGVLEFPDGH 243 Query 250 LEASTLGEIRVAGVRGREDSFYDFATKYLDDAAELDVPAKVDDQVAEAIRQLAIRAFAAI 309 LEASTLGEIRV GVRGRED FYDF TKYLDD AELDVPAKVDD VAEAIR L++RAF AI Sbjct 244 LEASTLGEIRVEGVRGREDGFYDFETKYLDDGAELDVPAKVDDDVAEAIRALSLRAFTAI 303 Query 310 DCRGLARVDFFLTDDGPVINEINTMPGFTTISMYPRMWAASGVDYPTLLATMIETTLARG 369 DC+GLARVDFFLTDDGPVINEINTMPGFTTISMYPRMWAASGVDYPTLLATM+ET LARG Sbjct 304 DCQGLARVDFFLTDDGPVINEINTMPGFTTISMYPRMWAASGVDYPTLLATMVETALARG 363 Query 370 VGLH 373 GL Sbjct 364 TGLR 367 >gi|126434497|ref|YP_001070188.1| D-alanyl-alanine synthetase A [Mycobacterium sp. JLS] gi|167012328|sp|A3PXS0.1|DDL_MYCSJ RecName: Full=D-alanine--D-alanine ligase; AltName: Full=D-Ala-D-Ala ligase; AltName: Full=D-alanylalanine synthetase gi|126234297|gb|ABN97697.1| D-alanine--D-alanine ligase [Mycobacterium sp. JLS] Length=371 Score = 585 bits (1508), Expect = 5e-165, Method: Compositional matrix adjust. Identities = 294/368 (80%), Positives = 323/368 (88%), Gaps = 1/368 (0%) Query 7 RDRRVRVAVVFGGRSNEHAISCVSAGSILRNLDSRRFDVIAVGITPAGSWVLTDANPDAL 66 R++R RVAVV+GGRS+EHAISCVSAGSILRNLD RFDV+AVGITP GSWVLTD P+ L Sbjct 4 RNQRTRVAVVYGGRSSEHAISCVSAGSILRNLDPERFDVVAVGITPDGSWVLTDGRPETL 63 Query 67 TITNRELPQVKSGSGTELALPADPRRGGQLVSLPPG-AGEVLESVDVVFPVLHGPYGEDG 125 IT+ LP+V + SGT LALPADP R G+LVSL P AGEVL +VDVVFPVLHGPYGEDG Sbjct 64 AITDGRLPEVSAESGTALALPADPGRRGELVSLSPAPAGEVLAAVDVVFPVLHGPYGEDG 123 Query 126 TIQGLLELAGVPYVGAGVLASAVGMDKEFTKKLLAADGLPVGAYAVLRPPRSTLHRQECE 185 TIQGLLELAGVPYVGAGVLASA GMDKEFTKKLL A+GLPVG + VLRP R+ + E E Sbjct 124 TIQGLLELAGVPYVGAGVLASAAGMDKEFTKKLLVAEGLPVGDHVVLRPGRANVTLDERE 183 Query 186 RLGLPVFVKPARGGSSIGVSRVSSWDQLPAAVARARRHDPKVIVEAAISGRELECGVLEM 245 RLGLPVFVKPARGGSSIGVSRVS W +LPAA+ ARRHDPKVIVEA I+GRELECGVLE Sbjct 184 RLGLPVFVKPARGGSSIGVSRVSDWAELPAAIEAARRHDPKVIVEAGIAGRELECGVLEY 243 Query 246 PDGTLEASTLGEIRVAGVRGREDSFYDFATKYLDDAAELDVPAKVDDQVAEAIRQLAIRA 305 PDG ++AST+GEIRVAGVRGRED FYDFATKYLDD AELDVPAKV+D VA+ IR+LAIRA Sbjct 244 PDGRVDASTIGEIRVAGVRGREDGFYDFATKYLDDGAELDVPAKVEDDVADEIRRLAIRA 303 Query 306 FAAIDCRGLARVDFFLTDDGPVINEINTMPGFTTISMYPRMWAASGVDYPTLLATMIETT 365 F AIDC+GLARVDFFLTDDGPV+NEINTMPGFTTISMYPRMWAASGVDYPTLLA M++T Sbjct 304 FRAIDCQGLARVDFFLTDDGPVVNEINTMPGFTTISMYPRMWAASGVDYPTLLAAMVDTA 363 Query 366 LARGVGLH 373 +ARG GL Sbjct 364 VARGTGLR 371 >gi|118468335|ref|YP_886735.1| D-alanyl-alanine synthetase A [Mycobacterium smegmatis str. MC2 155] gi|6919860|sp|Q9ZGN0.1|DDL_MYCSM RecName: Full=D-alanine--D-alanine ligase; AltName: Full=D-Ala-D-Ala ligase; AltName: Full=D-alanylalanine synthetase gi|166198492|sp|A0QUZ7.1|DDL_MYCS2 RecName: Full=D-alanine--D-alanine ligase; AltName: Full=D-Ala-D-Ala ligase; AltName: Full=D-alanylalanine synthetase gi|4092035|gb|AAC99396.1| D-alanine:D-alanine ligase [Mycobacterium smegmatis] gi|118169622|gb|ABK70518.1| D-alanine--D-alanine ligase [Mycobacterium smegmatis str. MC2 155] Length=373 Score = 584 bits (1505), Expect = 8e-165, Method: Compositional matrix adjust. Identities = 289/364 (80%), Positives = 320/364 (88%), Gaps = 0/364 (0%) Query 10 RVRVAVVFGGRSNEHAISCVSAGSILRNLDSRRFDVIAVGITPAGSWVLTDANPDALTIT 69 R RVAVV+GGRS+EHAISCVSAGSILRNLD RF+V+A+GITP GSWVLTD P+ L IT Sbjct 10 RTRVAVVYGGRSSEHAISCVSAGSILRNLDPERFEVVAIGITPDGSWVLTDGRPETLAIT 69 Query 70 NRELPQVKSGSGTELALPADPRRGGQLVSLPPGAGEVLESVDVVFPVLHGPYGEDGTIQG 129 + +LP V SGTELALPA P R GQL++L G GE+L +VDVVFPVLHGPYGEDGTIQG Sbjct 70 DGKLPAVTEASGTELALPAAPNRSGQLLALGNGPGEILAAVDVVFPVLHGPYGEDGTIQG 129 Query 130 LLELAGVPYVGAGVLASAVGMDKEFTKKLLAADGLPVGAYAVLRPPRSTLHRQECERLGL 189 LLELAGVPYVG+GVLASA GMDKE+TKKLLAA+GLP+G VLRP TL ++ ERLGL Sbjct 130 LLELAGVPYVGSGVLASAAGMDKEYTKKLLAAEGLPIGDQVVLRPGVETLDLEQRERLGL 189 Query 190 PVFVKPARGGSSIGVSRVSSWDQLPAAVARARRHDPKVIVEAAISGRELECGVLEMPDGT 249 PVFVKPARGGSSIGVSRV++WD+LPAAVA ARRHDPKVIVEAA+ GRELECGVLE PDG Sbjct 190 PVFVKPARGGSSIGVSRVTAWDELPAAVALARRHDPKVIVEAAVIGRELECGVLEFPDGR 249 Query 250 LEASTLGEIRVAGVRGREDSFYDFATKYLDDAAELDVPAKVDDQVAEAIRQLAIRAFAAI 309 LEAST+GEIRVAGVRGRED FYDFATKYL+DAAELDVPAKVDD VA+ IRQLA+RAF AI Sbjct 250 LEASTVGEIRVAGVRGREDGFYDFATKYLEDAAELDVPAKVDDDVADEIRQLAVRAFTAI 309 Query 310 DCRGLARVDFFLTDDGPVINEINTMPGFTTISMYPRMWAASGVDYPTLLATMIETTLARG 369 C+GLARVDFFLTDDGPVINEINTMPGFTTISMYPRMWAA G+DYPTLLA M++T +ARG Sbjct 310 GCQGLARVDFFLTDDGPVINEINTMPGFTTISMYPRMWAAGGIDYPTLLAAMVDTAIARG 369 Query 370 VGLH 373 GL Sbjct 370 TGLR 373 >gi|315445128|ref|YP_004078007.1| D-alanine--D-alanine ligase [Mycobacterium sp. Spyr1] gi|315263431|gb|ADU00173.1| D-alanine--D-alanine ligase [Mycobacterium sp. Spyr1] Length=367 Score = 582 bits (1501), Expect = 3e-164, Method: Compositional matrix adjust. Identities = 293/364 (81%), Positives = 315/364 (87%), Gaps = 0/364 (0%) Query 10 RVRVAVVFGGRSNEHAISCVSAGSILRNLDSRRFDVIAVGITPAGSWVLTDANPDALTIT 69 R+RVAVV+GGRS+EHAISCVSAGSILRNLD RF+V AVGITP GSWVLT+ P+ L IT Sbjct 4 RIRVAVVYGGRSSEHAISCVSAGSILRNLDPDRFEVTAVGITPEGSWVLTEGRPETLAIT 63 Query 70 NRELPQVKSGSGTELALPADPRRGGQLVSLPPGAGEVLESVDVVFPVLHGPYGEDGTIQG 129 + +LP V SGT L L ADP R GQLVSL AGEVL S DVVFPVLHGPYGEDGTIQG Sbjct 64 DGKLPGVTGDSGTALTLTADPARRGQLVSLGEAAGEVLASADVVFPVLHGPYGEDGTIQG 123 Query 130 LLELAGVPYVGAGVLASAVGMDKEFTKKLLAADGLPVGAYAVLRPPRSTLHRQECERLGL 189 LLELAGVPYVGAGVLASA GMDKEFTKKLLA+ GLPVG + VLR STL Q+ ERLGL Sbjct 124 LLELAGVPYVGAGVLASAAGMDKEFTKKLLASAGLPVGDHVVLRARDSTLSLQDRERLGL 183 Query 190 PVFVKPARGGSSIGVSRVSSWDQLPAAVARARRHDPKVIVEAAISGRELECGVLEMPDGT 249 PVFVKP+RGGSSIGVSRV++WD+LPAA+ ARRHDPKVI+EAA+ GRELECGVLE PDG Sbjct 184 PVFVKPSRGGSSIGVSRVTAWDELPAAIELARRHDPKVIIEAAVPGRELECGVLEFPDGH 243 Query 250 LEASTLGEIRVAGVRGREDSFYDFATKYLDDAAELDVPAKVDDQVAEAIRQLAIRAFAAI 309 LEASTLGEIRV GVRGRED FYDF TKYLDD AELDVPAKVDD VAEAIR L++RAF AI Sbjct 244 LEASTLGEIRVEGVRGREDGFYDFETKYLDDGAELDVPAKVDDDVAEAIRALSLRAFTAI 303 Query 310 DCRGLARVDFFLTDDGPVINEINTMPGFTTISMYPRMWAASGVDYPTLLATMIETTLARG 369 DC+GLARVDFFLTDDGPVINEINTMPGFTTISMYPRMWAASGVDY TLLATM+ET LARG Sbjct 304 DCQGLARVDFFLTDDGPVINEINTMPGFTTISMYPRMWAASGVDYQTLLATMVETALARG 363 Query 370 VGLH 373 GL Sbjct 364 TGLR 367 >gi|120403135|ref|YP_952964.1| D-alanyl-alanine synthetase A [Mycobacterium vanbaalenii PYR-1] gi|190359169|sp|A1T708.1|DDL_MYCVP RecName: Full=D-alanine--D-alanine ligase; AltName: Full=D-Ala-D-Ala ligase; AltName: Full=D-alanylalanine synthetase gi|119955953|gb|ABM12958.1| D-alanine--D-alanine ligase [Mycobacterium vanbaalenii PYR-1] Length=367 Score = 582 bits (1499), Expect = 5e-164, Method: Compositional matrix adjust. Identities = 291/364 (80%), Positives = 318/364 (88%), Gaps = 0/364 (0%) Query 10 RVRVAVVFGGRSNEHAISCVSAGSILRNLDSRRFDVIAVGITPAGSWVLTDANPDALTIT 69 R+RVAVV+GGRS+EHAISCVSAGSILRNLD +RF+V+ VGITP GSWVLTD P+ L IT Sbjct 4 RIRVAVVYGGRSSEHAISCVSAGSILRNLDPQRFEVVPVGITPEGSWVLTDGRPETLAIT 63 Query 70 NRELPQVKSGSGTELALPADPRRGGQLVSLPPGAGEVLESVDVVFPVLHGPYGEDGTIQG 129 + LP V SGTELAL ADP R GQL+SL AG+VL +VDVVFPVLHGPYGEDGTIQG Sbjct 64 DGALPGVSGSSGTELALAADPGRRGQLLSLGDAAGDVLAAVDVVFPVLHGPYGEDGTIQG 123 Query 130 LLELAGVPYVGAGVLASAVGMDKEFTKKLLAADGLPVGAYAVLRPPRSTLHRQECERLGL 189 LLELAGVPYVGAGVLASA GMDKEFTKKLL A GLPVG + VLRP +T+ ++ ERLGL Sbjct 124 LLELAGVPYVGAGVLASAAGMDKEFTKKLLTAAGLPVGDHVVLRPREATVSLEDRERLGL 183 Query 190 PVFVKPARGGSSIGVSRVSSWDQLPAAVARARRHDPKVIVEAAISGRELECGVLEMPDGT 249 PVFVKP+RGGSSIGVSRV++WD LPAA+ ARRHDPKVIVEAAI GRELECGVLE PDG Sbjct 184 PVFVKPSRGGSSIGVSRVTAWDALPAAIELARRHDPKVIVEAAIPGRELECGVLEFPDGH 243 Query 250 LEASTLGEIRVAGVRGREDSFYDFATKYLDDAAELDVPAKVDDQVAEAIRQLAIRAFAAI 309 LEAST+GEIRVAGVRGRED FYDF TKYLDD AELDVPAKVDD +AEA+R LAIRAF AI Sbjct 244 LEASTVGEIRVAGVRGREDGFYDFETKYLDDGAELDVPAKVDDAIAEAVRGLAIRAFDAI 303 Query 310 DCRGLARVDFFLTDDGPVINEINTMPGFTTISMYPRMWAASGVDYPTLLATMIETTLARG 369 DC+GLARVDFFLTD GPVINEINTMPGFTTISMYPRMWAASG+DYPTLLATM+ET +ARG Sbjct 304 DCQGLARVDFFLTDAGPVINEINTMPGFTTISMYPRMWAASGIDYPTLLATMVETAIARG 363 Query 370 VGLH 373 GL Sbjct 364 TGLR 367 >gi|333991324|ref|YP_004523938.1| d-alanine--D-alanine ligase DdlA [Mycobacterium sp. JDM601] gi|333487292|gb|AEF36684.1| d-alanine--D-alanine ligase DdlA [Mycobacterium sp. JDM601] Length=363 Score = 569 bits (1467), Expect = 2e-160, Method: Compositional matrix adjust. Identities = 286/362 (80%), Positives = 319/362 (89%), Gaps = 2/362 (0%) Query 13 VAVVFGGRSNEHAISCVSAGSILRNLDSRRFDVIAVGITPAGSWVLTDANPDALTITNRE 72 +AVVFGGRS+EHAISCVSAGSILRNLD +RF+VIAVGITP GSWVLT +PDA I+ R+ Sbjct 1 MAVVFGGRSSEHAISCVSAGSILRNLDPQRFEVIAVGITPEGSWVLTSGDPDAWAISGRQ 60 Query 73 LPQVKSGSGTELALPADPRRGGQLVSLPPGA-GEVLESVDVVFPVLHGPYGEDGTIQGLL 131 LP V SG EL LPADP+R GQLV+L GA E+L SVDVVFPVLHGPYGEDGT+QGLL Sbjct 61 LPAVSKASGAELTLPADPQRSGQLVALSGGAPTELLASVDVVFPVLHGPYGEDGTVQGLL 120 Query 132 ELAGVPYVGAGVLASAVGMDKEFTKKLLAADGLPVGAYAVLRPPRSTLHRQECERLGLPV 191 ELAGVPYVGAGVLASA GMDKEFTKKLLAA+GLP+G YAVLR ++TL ++ ERLGLP+ Sbjct 121 ELAGVPYVGAGVLASAAGMDKEFTKKLLAAEGLPIGPYAVLRANQATLSIEDRERLGLPL 180 Query 192 FVKPARGGSSIGVSRVSSWDQLPAAVARARRHDPKVIVEAAISGRELECGVLEMPDGTLE 251 FVKPARGGSSIGV+RV+S D+LPAA+A ARRHDPKVIVEAAI GRELECGVLE PDGT+ Sbjct 181 FVKPARGGSSIGVTRVASHDELPAAIAEARRHDPKVIVEAAIVGRELECGVLEFPDGTVA 240 Query 252 ASTLGEIRVA-GVRGREDSFYDFATKYLDDAAELDVPAKVDDQVAEAIRQLAIRAFAAID 310 AST+GEIRV G +DSFYDFATKYLDDAAELDVPAK+DD+VA+ +RQLAIRAFAA+D Sbjct 241 ASTVGEIRVVRGCAEHDDSFYDFATKYLDDAAELDVPAKIDDEVADTVRQLAIRAFAALD 300 Query 311 CRGLARVDFFLTDDGPVINEINTMPGFTTISMYPRMWAASGVDYPTLLATMIETTLARGV 370 C+GLARVDFF TD GPVINEINTMPGFTTISMYPRMW ASGVDYPTLLATM++T ARGV Sbjct 301 CQGLARVDFFHTDAGPVINEINTMPGFTTISMYPRMWEASGVDYPTLLATMVDTAQARGV 360 Query 371 GL 372 GL Sbjct 361 GL 362 >gi|169630367|ref|YP_001704016.1| D-alanyl-alanine synthetase A [Mycobacterium abscessus ATCC 19977] gi|169242334|emb|CAM63362.1| Probable D-alanine--D-alanine ligase DdlA [Mycobacterium abscessus] Length=381 Score = 541 bits (1395), Expect = 5e-152, Method: Compositional matrix adjust. Identities = 269/369 (73%), Positives = 307/369 (84%), Gaps = 4/369 (1%) Query 9 RRVRVAVVFGGRSNEHAISCVSAGSILRNLDSRRFDVIAVGITPAGSWVLTDANPDALTI 68 +R++VA+VFGGRS+EHAISCVSAGSILRNLD ++V+AVG+TP G WVLTD +P L I Sbjct 13 QRIKVALVFGGRSSEHAISCVSAGSILRNLDQAVYEVVAVGVTPEGGWVLTDGDPAQLAI 72 Query 69 TNRELPQVKSGSGTELALPADPRRGGQLVSL-PPGAGEVLESVDVVFPVLHGPYGEDGTI 127 ++R LPQV SGTEL L DPRR GQLV++ AG+VL SVDVVFPVLHGPYGEDGTI Sbjct 73 SDRTLPQVTDASGTELLLATDPRRAGQLVNVDSSAAGQVLASVDVVFPVLHGPYGEDGTI 132 Query 128 QGLLELAGVPYVGAGVLASAVGMDKEFTKKLLAADGLPVGAYAVLRPPRSTLHRQECERL 187 QGLLELAGVPYVGAGVLASA GMDKEFTKKLLAA+GLP+G YAV+RP +TL + E L Sbjct 133 QGLLELAGVPYVGAGVLASAAGMDKEFTKKLLAAEGLPIGKYAVIRPRDTTLTLDQREDL 192 Query 188 GLPVFVKPARGGSSIGVSRVSSWDQLPAAVARARRHDPKVIVEAAISGRELECGVLEMPD 247 GLPVFVKPAR GSS GVSRV++W++LPAA+A AR++DPKVIVEAAI GRELECGVLE PD Sbjct 193 GLPVFVKPARAGSSFGVSRVTAWEELPAAIAHARQYDPKVIVEAAIVGRELECGVLEFPD 252 Query 248 GTLEASTLGEIRVAGVRGRED---SFYDFATKYLDDAAELDVPAKVDDQVAEAIRQLAIR 304 G AS LGEIRV GV + +FYDF TKYLDD AELDVPAKVDD V++ IR+LA+ Sbjct 253 GDTRASVLGEIRVEGVNRDQTAAGAFYDFETKYLDDTAELDVPAKVDDDVSDQIRELAVA 312 Query 305 AFAAIDCRGLARVDFFLTDDGPVINEINTMPGFTTISMYPRMWAASGVDYPTLLATMIET 364 AF AIDC+GLARVDFFL +DGP+INEINTMPGFTTISMYPRMW A+GVDYPTLL M+ T Sbjct 313 AFRAIDCQGLARVDFFLAEDGPLINEINTMPGFTTISMYPRMWDATGVDYPTLLDAMVRT 372 Query 365 TLARGVGLH 373 LARG GL Sbjct 373 ALARGTGLR 381 >gi|312140476|ref|YP_004007812.1| d-alanine-d-alanine ligase [Rhodococcus equi 103S] gi|311889815|emb|CBH49132.1| D-alanine-D-alanine ligase [Rhodococcus equi 103S] Length=368 Score = 497 bits (1279), Expect = 2e-138, Method: Compositional matrix adjust. Identities = 246/365 (68%), Positives = 292/365 (80%), Gaps = 2/365 (0%) Query 10 RVRVAVVFGGRSNEHAISCVSAGSILRNLDSRRFDVIAVGITPAGSWVLTDANPDALTIT 69 R RVAVVFGGRSNEH++SCVSAGS+LRNLD R++V+ +GIT G+WVL +P L I Sbjct 5 RTRVAVVFGGRSNEHSVSCVSAGSVLRNLDPDRYEVVPIGITTDGAWVLGSTDPADLAIR 64 Query 70 NRELPQVKSGSGTELALPADPRRGGQLVSLP-PGAGEVLESVDVVFPVLHGPYGEDGTIQ 128 +R +P V +G G L L ADP R G +V+L AG+ L SVDVVFPVLHG YGEDGTIQ Sbjct 65 DRSMPTVDAG-GKALTLTADPTRAGAVVALDDKQAGQALASVDVVFPVLHGAYGEDGTIQ 123 Query 129 GLLELAGVPYVGAGVLASAVGMDKEFTKKLLAADGLPVGAYAVLRPPRSTLHRQECERLG 188 GLLELAG+PYVG GVLASA GMDKEFTKKLLAA+GLPVG VLRP ST+ ++ ++LG Sbjct 124 GLLELAGIPYVGPGVLASAAGMDKEFTKKLLAAEGLPVGFQVVLRPGTSTVTDEQKQQLG 183 Query 189 LPVFVKPARGGSSIGVSRVSSWDQLPAAVARARRHDPKVIVEAAISGRELECGVLEMPDG 248 LPVFVKPARGGSSIG++RV+ W Q AAVA AR HDPKVIVE+AI GRE+ECGVLE PDG Sbjct 184 LPVFVKPARGGSSIGITRVADWSQFDAAVAVARSHDPKVIVESAIVGREVECGVLEFPDG 243 Query 249 TLEASTLGEIRVAGVRGREDSFYDFATKYLDDAAELDVPAKVDDQVAEAIRQLAIRAFAA 308 + AS + EIR+ G E +FYDF TKYLDD E DVPAK+DD V+E IR LA+RAF A Sbjct 244 DVRASVVAEIRMPDTDGDESAFYDFDTKYLDDVCEFDVPAKLDDDVSEQIRALAVRAFRA 303 Query 309 IDCRGLARVDFFLTDDGPVINEINTMPGFTTISMYPRMWAASGVDYPTLLATMIETTLAR 368 +DC+GLARVDFF+T DGPVINEINTMPGFT+ISMYPRMW A+GV+Y TL++T+++T +AR Sbjct 304 LDCQGLARVDFFVTADGPVINEINTMPGFTSISMYPRMWQAAGVEYETLVSTLVDTAVAR 363 Query 369 GVGLH 373 G GL Sbjct 364 GTGLR 368 >gi|111023466|ref|YP_706438.1| D-alanyl-alanine synthetase A [Rhodococcus jostii RHA1] gi|123339682|sp|Q0S2F6.1|DDL_RHOSR RecName: Full=D-alanine--D-alanine ligase; AltName: Full=D-Ala-D-Ala ligase; AltName: Full=D-alanylalanine synthetase gi|110822996|gb|ABG98280.1| D-alanine--D-alanine ligase [Rhodococcus jostii RHA1] Length=368 Score = 496 bits (1277), Expect = 2e-138, Method: Compositional matrix adjust. Identities = 244/364 (68%), Positives = 296/364 (82%), Gaps = 2/364 (0%) Query 10 RVRVAVVFGGRSNEHAISCVSAGSILRNLDSRRFDVIAVGITPAGSWVLTDANPDALTIT 69 R RVAV+FGGRSNEH++SCVSAGS+LRNLD R++V+ +GIT GSWVL +P+ L+I Sbjct 5 RTRVAVIFGGRSNEHSVSCVSAGSVLRNLDPERYEVVPIGITTEGSWVLGSTDPETLSIR 64 Query 70 NRELPQVKSGSGTELALPADPRRGGQLVSLPPG-AGEVLESVDVVFPVLHGPYGEDGTIQ 128 R LP V + G+ LAL ADP R G LV+L G AG++L SVDVVFPVLHG YGEDGTIQ Sbjct 65 GRALPSVDA-DGSALALTADPTRSGDLVALDDGEAGKILASVDVVFPVLHGAYGEDGTIQ 123 Query 129 GLLELAGVPYVGAGVLASAVGMDKEFTKKLLAADGLPVGAYAVLRPPRSTLHRQECERLG 188 GLLELAGVPYVG GVLASA GMDKEFTKKLLAA+GLP+G VLRP +TL ++ RL Sbjct 124 GLLELAGVPYVGPGVLASAAGMDKEFTKKLLAAEGLPIGFQVVLRPGTATLTDEQKSRLH 183 Query 189 LPVFVKPARGGSSIGVSRVSSWDQLPAAVARARRHDPKVIVEAAISGRELECGVLEMPDG 248 LPVFVKPARGGSSIG++RV+ W L A+A AR HDPKVIVE+ I GRE+ECGVLE PDG Sbjct 184 LPVFVKPARGGSSIGITRVAEWAALDDAIAHARLHDPKVIVESGIIGREVECGVLEFPDG 243 Query 249 TLEASTLGEIRVAGVRGREDSFYDFATKYLDDAAELDVPAKVDDQVAEAIRQLAIRAFAA 308 + AS + EIR+ G +++FYDF +KYLDD E DVPAK+D+ V++ IR+LA+RAF+A Sbjct 244 DVRASVIAEIRMPEGAGDDEAFYDFDSKYLDDVCEFDVPAKLDESVSDEIRELAVRAFSA 303 Query 309 IDCRGLARVDFFLTDDGPVINEINTMPGFTTISMYPRMWAASGVDYPTLLATMIETTLAR 368 +DC+GLARVDFF+T+DGPVINEINTMPGFT+ISMYPRMW A GVDY TL++T+++T LAR Sbjct 304 LDCQGLARVDFFVTEDGPVINEINTMPGFTSISMYPRMWGAVGVDYGTLVSTLVDTALAR 363 Query 369 GVGL 372 G+GL Sbjct 364 GIGL 367 >gi|226365967|ref|YP_002783750.1| D-alanyl-alanine synthetase A [Rhodococcus opacus B4] gi|254767736|sp|C1B2N8.1|DDL_RHOOB RecName: Full=D-alanine--D-alanine ligase; AltName: Full=D-Ala-D-Ala ligase; AltName: Full=D-alanylalanine synthetase gi|226244457|dbj|BAH54805.1| D-alanine--D-alanine ligase [Rhodococcus opacus B4] Length=368 Score = 495 bits (1275), Expect = 4e-138, Method: Compositional matrix adjust. Identities = 244/364 (68%), Positives = 296/364 (82%), Gaps = 2/364 (0%) Query 10 RVRVAVVFGGRSNEHAISCVSAGSILRNLDSRRFDVIAVGITPAGSWVLTDANPDALTIT 69 R RVAV+FGGRSNEH++SCVSAGS+LRNLD R++V+ +GIT GSWVL +P++L+I Sbjct 5 RTRVAVIFGGRSNEHSVSCVSAGSVLRNLDPERYEVVPIGITTEGSWVLGSTDPESLSIR 64 Query 70 NRELPQVKSGSGTELALPADPRRGGQLVSLPPG-AGEVLESVDVVFPVLHGPYGEDGTIQ 128 R LP V + G+ LAL ADP R G LV+L G AG++L SVDVVFPVLHG YGEDGTIQ Sbjct 65 GRSLPSVDA-DGSALALTADPTRSGDLVALDDGEAGKILASVDVVFPVLHGAYGEDGTIQ 123 Query 129 GLLELAGVPYVGAGVLASAVGMDKEFTKKLLAADGLPVGAYAVLRPPRSTLHRQECERLG 188 GLLELAGVPYVG GVLASA GMDKEFTKKLLAA+GLP+G VLRP +TL ++ RL Sbjct 124 GLLELAGVPYVGPGVLASAAGMDKEFTKKLLAAEGLPIGFQVVLRPGTATLTDEQRSRLH 183 Query 189 LPVFVKPARGGSSIGVSRVSSWDQLPAAVARARRHDPKVIVEAAISGRELECGVLEMPDG 248 LPVFVKPARGGSSIG++RV+ W L A+A ARRHDPKVIVE+ I+GRE+ECGVLE PDG Sbjct 184 LPVFVKPARGGSSIGITRVAEWAALDDAIAHARRHDPKVIVESGIAGREVECGVLEFPDG 243 Query 249 TLEASTLGEIRVAGVRGREDSFYDFATKYLDDAAELDVPAKVDDQVAEAIRQLAIRAFAA 308 + AS + EIR+ +++FYDF +KYLDD E DVPAK++D V++ IR LA+RAF+A Sbjct 244 DVRASVIAEIRMPEGADDDEAFYDFDSKYLDDVCEFDVPAKLEDSVSDEIRALAVRAFSA 303 Query 309 IDCRGLARVDFFLTDDGPVINEINTMPGFTTISMYPRMWAASGVDYPTLLATMIETTLAR 368 +DC+GLARVDFF+T+DGPVINEINTMPGFT+ISMYPRMW A GVDY TL++T+++T LAR Sbjct 304 LDCQGLARVDFFVTEDGPVINEINTMPGFTSISMYPRMWDAVGVDYGTLVSTLVDTALAR 363 Query 369 GVGL 372 G GL Sbjct 364 GTGL 367 >gi|325675906|ref|ZP_08155590.1| D-alanine-D-alanine ligase [Rhodococcus equi ATCC 33707] gi|325553877|gb|EGD23555.1| D-alanine-D-alanine ligase [Rhodococcus equi ATCC 33707] Length=368 Score = 495 bits (1274), Expect = 6e-138, Method: Compositional matrix adjust. Identities = 245/365 (68%), Positives = 291/365 (80%), Gaps = 2/365 (0%) Query 10 RVRVAVVFGGRSNEHAISCVSAGSILRNLDSRRFDVIAVGITPAGSWVLTDANPDALTIT 69 R RVAVVFGGRSNEH++SCVSAGS+LRNLD R++V+ +GIT G+WVL +P L I Sbjct 5 RTRVAVVFGGRSNEHSVSCVSAGSVLRNLDPDRYEVVPIGITTDGAWVLGSTDPADLAIR 64 Query 70 NRELPQVKSGSGTELALPADPRRGGQLVSLP-PGAGEVLESVDVVFPVLHGPYGEDGTIQ 128 +R +P V + G L L ADP R G +V+L AG+ L SVDVVFPVLHG YGEDGTIQ Sbjct 65 DRSMPTVDA-DGKALTLTADPTRAGAVVALDDKQAGQALASVDVVFPVLHGAYGEDGTIQ 123 Query 129 GLLELAGVPYVGAGVLASAVGMDKEFTKKLLAADGLPVGAYAVLRPPRSTLHRQECERLG 188 GLLELAG+PYVG GVLASA GMDKEFTKKLLAA+GLPVG VLRP ST+ ++ ++LG Sbjct 124 GLLELAGIPYVGPGVLASAAGMDKEFTKKLLAAEGLPVGFQVVLRPGTSTVTDEQKQQLG 183 Query 189 LPVFVKPARGGSSIGVSRVSSWDQLPAAVARARRHDPKVIVEAAISGRELECGVLEMPDG 248 LPVFVKPARGGSSIG++RV+ W Q AAVA AR HDPKVIVE+AI GRE+ECGVLE PDG Sbjct 184 LPVFVKPARGGSSIGITRVADWSQFDAAVAVARSHDPKVIVESAIVGREVECGVLEFPDG 243 Query 249 TLEASTLGEIRVAGVRGREDSFYDFATKYLDDAAELDVPAKVDDQVAEAIRQLAIRAFAA 308 + AS + EIR+ G E +FYDF TKYLDD E DVPAK+DD V+E IR LA+RAF A Sbjct 244 DVRASVVAEIRMPDTDGDESAFYDFDTKYLDDVCEFDVPAKLDDDVSEQIRALAVRAFRA 303 Query 309 IDCRGLARVDFFLTDDGPVINEINTMPGFTTISMYPRMWAASGVDYPTLLATMIETTLAR 368 +DC+GLARVDFF+T DGPVINEINTMPGFT+ISMYPRMW A+GV+Y TL++T+++T +AR Sbjct 304 LDCQGLARVDFFVTADGPVINEINTMPGFTSISMYPRMWQAAGVEYETLVSTLVDTAVAR 363 Query 369 GVGLH 373 G GL Sbjct 364 GTGLR 368 >gi|226305903|ref|YP_002765863.1| D-alanine--D-alanine ligase [Rhodococcus erythropolis PR4] gi|259645171|sp|C0ZXN9.1|DDL_RHOE4 RecName: Full=D-alanine--D-alanine ligase; AltName: Full=D-Ala-D-Ala ligase; AltName: Full=D-alanylalanine synthetase gi|226185020|dbj|BAH33124.1| D-alanine--D-alanine ligase [Rhodococcus erythropolis PR4] Length=368 Score = 492 bits (1267), Expect = 3e-137, Method: Compositional matrix adjust. Identities = 240/364 (66%), Positives = 291/364 (80%), Gaps = 2/364 (0%) Query 10 RVRVAVVFGGRSNEHAISCVSAGSILRNLDSRRFDVIAVGITPAGSWVLTDANPDALTIT 69 R RVAV+FGGRSNEH++SCVSAGS+L NLD R+DV+ +GIT GSWVL ++P +L I+ Sbjct 5 RTRVAVIFGGRSNEHSVSCVSAGSVLSNLDPDRYDVVPIGITVDGSWVLGSSDPSSLAIS 64 Query 70 NRELPQVKSGSGTELALPADPRRGGQLVSLP-PGAGEVLESVDVVFPVLHGPYGEDGTIQ 128 R LP V GT + L ADP R G+++S AG VL SVDVVFPVLHG YGEDGTIQ Sbjct 65 GRALPSVDK-DGTSVVLSADPTREGEVISFDGSDAGAVLASVDVVFPVLHGAYGEDGTIQ 123 Query 129 GLLELAGVPYVGAGVLASAVGMDKEFTKKLLAADGLPVGAYAVLRPPRSTLHRQECERLG 188 GLLELAGVPYVG GVLASA GMDKEFTKKLLAA+GLPVG VLRP +TL ++ LG Sbjct 124 GLLELAGVPYVGPGVLASAAGMDKEFTKKLLAAEGLPVGVQVVLRPGIATLTEEQKAELG 183 Query 189 LPVFVKPARGGSSIGVSRVSSWDQLPAAVARARRHDPKVIVEAAISGRELECGVLEMPDG 248 LPVFVKPARGGSSIG++RVS+WD L A+A AR HDPKVIVE AI GRE+ECGVLE P+G Sbjct 184 LPVFVKPARGGSSIGITRVSNWDGLDGAIAHARLHDPKVIVEGAIIGREVECGVLEFPNG 243 Query 249 TLEASTLGEIRVAGVRGREDSFYDFATKYLDDAAELDVPAKVDDQVAEAIRQLAIRAFAA 308 ++AS + EIR+ D+FYDF TKYLDD E D+PAK+D+ V++ IR+LA+RAF A Sbjct 244 DVKASVVAEIRMPDADTDSDAFYDFDTKYLDDVCEFDIPAKLDESVSDQIRELAVRAFKA 303 Query 309 IDCRGLARVDFFLTDDGPVINEINTMPGFTTISMYPRMWAASGVDYPTLLATMIETTLAR 368 +DC+GL+RVDFF+T DGPVINEINTMPGFT+ISMYP+MW A+G+DY TL++T+++T +AR Sbjct 304 LDCQGLSRVDFFVTADGPVINEINTMPGFTSISMYPKMWNATGIDYRTLISTLVDTAIAR 363 Query 369 GVGL 372 G GL Sbjct 364 GTGL 367 >gi|229491375|ref|ZP_04385199.1| D-alanine--D-alanine ligase [Rhodococcus erythropolis SK121] gi|229321660|gb|EEN87457.1| D-alanine--D-alanine ligase [Rhodococcus erythropolis SK121] Length=368 Score = 491 bits (1265), Expect = 6e-137, Method: Compositional matrix adjust. Identities = 240/365 (66%), Positives = 290/365 (80%), Gaps = 2/365 (0%) Query 10 RVRVAVVFGGRSNEHAISCVSAGSILRNLDSRRFDVIAVGITPAGSWVLTDANPDALTIT 69 R RVAV+FGGRSNEH++SCVSAGS+L NLD R+DV+ +GIT GSWVL ++P +L I Sbjct 5 RTRVAVIFGGRSNEHSVSCVSAGSVLSNLDPDRYDVVPIGITVDGSWVLGSSDPSSLAIR 64 Query 70 NRELPQVKSGSGTELALPADPRRGGQLVSLP-PGAGEVLESVDVVFPVLHGPYGEDGTIQ 128 R LP V GT + L ADP R G+++S AG VL SVDVVFPVLHG YGEDGTIQ Sbjct 65 GRALPSVDK-DGTSVVLSADPTREGEVISFDGSDAGAVLASVDVVFPVLHGAYGEDGTIQ 123 Query 129 GLLELAGVPYVGAGVLASAVGMDKEFTKKLLAADGLPVGAYAVLRPPRSTLHRQECERLG 188 GLLELAGVPYVG GVLASA GMDKEFTKKLLAA+GLPVG VLRP +TL ++ LG Sbjct 124 GLLELAGVPYVGPGVLASAAGMDKEFTKKLLAAEGLPVGVQVVLRPGTATLTEEQKAELG 183 Query 189 LPVFVKPARGGSSIGVSRVSSWDQLPAAVARARRHDPKVIVEAAISGRELECGVLEMPDG 248 LPVFVKPARGGSSIG++RVS+WD L A+A AR HDPKVIVE AI GRE+ECGVLE P+G Sbjct 184 LPVFVKPARGGSSIGITRVSNWDGLDGAIAHARLHDPKVIVEGAIIGREVECGVLEFPNG 243 Query 249 TLEASTLGEIRVAGVRGREDSFYDFATKYLDDAAELDVPAKVDDQVAEAIRQLAIRAFAA 308 ++AS + EIR+ D+FYDF TKYLDD E D+PAK+D+ V++ IR+LA+RAF A Sbjct 244 DVKASVVAEIRMPDSDADSDAFYDFDTKYLDDVCEFDIPAKLDESVSDQIRELAVRAFKA 303 Query 309 IDCRGLARVDFFLTDDGPVINEINTMPGFTTISMYPRMWAASGVDYPTLLATMIETTLAR 368 +DC+GL+RVDFF+T DGPVINEINTMPGFT+ISMYP+MW A+G+DY TL++T+++T +AR Sbjct 304 LDCQGLSRVDFFVTADGPVINEINTMPGFTSISMYPKMWNATGIDYRTLISTLVDTAVAR 363 Query 369 GVGLH 373 G GL Sbjct 364 GTGLR 368 >gi|54026176|ref|YP_120418.1| D-alanyl-alanine synthetase A [Nocardia farcinica IFM 10152] gi|81373693|sp|Q5YRY7.1|DDL_NOCFA RecName: Full=D-alanine--D-alanine ligase; AltName: Full=D-Ala-D-Ala ligase; AltName: Full=D-alanylalanine synthetase gi|54017684|dbj|BAD59054.1| putative D-alanine-D-alanine ligase [Nocardia farcinica IFM 10152] Length=363 Score = 488 bits (1255), Expect = 9e-136, Method: Compositional matrix adjust. Identities = 245/364 (68%), Positives = 293/364 (81%), Gaps = 4/364 (1%) Query 9 RRVRVAVVFGGRSNEHAISCVSAGSILRNLDSRRFDVIAVGITPAGSWVLTDANPDALTI 68 R+RVAVVFGGRSNEHA+SCVSAGS+LR+LD R++ + +GITP G WVL +++ A+ + Sbjct 3 NRIRVAVVFGGRSNEHAVSCVSAGSVLRHLDPTRYEAVPIGITPQGGWVLANSDVAAIGL 62 Query 69 TNRELPQVKSGSGTELALPADPRRGGQLVSLPPGAGEVLESVDVVFPVLHGPYGEDGTIQ 128 ++ LP V +G GT L L ADP RGG+LV+L AG VL +VDVVFP+LHGP+GEDGT+Q Sbjct 63 SHEALPSVDAG-GTALTLTADPTRGGELVALD-DAGAVLGTVDVVFPILHGPFGEDGTLQ 120 Query 129 GLLELAGVPYVGAGVLASAVGMDKEFTKKLLAADGLPVGAYAVLRPPRSTLHRQECERLG 188 G+LELAGVPYVG GVLASA GMDKEFTKKLLAA+GLPVG VLRP +TL ++ ERLG Sbjct 121 GMLELAGVPYVGPGVLASAAGMDKEFTKKLLAAEGLPVGTQVVLRPGTATLTEEQRERLG 180 Query 189 LPVFVKPARGGSSIGVSRVSSWDQLPAAVARARRHDPKVIVEAAISGRELECGVLEMPDG 248 LPVFVKPAR GSSIG+++V W L A+A AR HDPKVIVEA I GRE+ECGVLE PDG Sbjct 181 LPVFVKPARAGSSIGITKVDDWAALDTAIAAAREHDPKVIVEAGIVGREVECGVLEFPDG 240 Query 249 TLEASTLGEIRVAGVRGREDSFYDFATKYLDDAAELDVPAKVDDQVAEAIRQLAIRAFAA 308 + AS L EIR+ G FYDF TKYLDD E DVPAK+DD +AE +R+LA+RAF A Sbjct 241 RISASVLAEIRMP--EGDGPQFYDFDTKYLDDVCEFDVPAKLDDDIAEQVRELAVRAFQA 298 Query 309 IDCRGLARVDFFLTDDGPVINEINTMPGFTTISMYPRMWAASGVDYPTLLATMIETTLAR 368 +DC+GLARVDFF+T DGPVINEINTMPGFT+ISMYPRMW A+G+DY TL++T+IET LAR Sbjct 299 LDCQGLARVDFFVTADGPVINEINTMPGFTSISMYPRMWEATGIDYGTLVSTLIETALAR 358 Query 369 GVGL 372 G GL Sbjct 359 GTGL 362 >gi|331698554|ref|YP_004334793.1| D-alanine--D-alanine ligase [Pseudonocardia dioxanivorans CB1190] gi|326953243|gb|AEA26940.1| D-alanine--D-alanine ligase [Pseudonocardia dioxanivorans CB1190] Length=365 Score = 478 bits (1229), Expect = 1e-132, Method: Compositional matrix adjust. Identities = 247/367 (68%), Positives = 287/367 (79%), Gaps = 5/367 (1%) Query 8 DRRVRVAVVFGGRSNEHAISCVSAGSILRNLDSRRFDVIAVGITPAGSWVLTDANPDALT 67 +RR RVAVVFGGRS+EH ISCVSAGS+L +LD RFDV+ VGITP G+WVL +P L Sbjct 3 ERRTRVAVVFGGRSSEHTISCVSAGSVLAHLDRDRFDVVPVGITPDGAWVLGTDDPARLR 62 Query 68 ITNRELPQVKSGSGTELALPADPRRGGQLVSLPPGAGEVLESVDVVFPVLHGPYGEDGTI 127 I R LP V G+G LALP DP RGG + AGEV VDVVFPVLHGP+GEDGTI Sbjct 63 IDGRTLPVV-DGTGAALALPGDPTRGGLVRLDRDRAGEVFSGVDVVFPVLHGPFGEDGTI 121 Query 128 QGLLELAGVPYVGAGVLASAVGMDKEFTKKLLAADGLPVGAYAVLRPPRSTLHRQECERL 187 QGL E+AG+PYVG+GVLASA GMDKEFTKKLLAA+GL VG+ VLRP +L + ERL Sbjct 122 QGLFEMAGLPYVGSGVLASAAGMDKEFTKKLLAAEGLAVGSLVVLRPGTQSLTAAQQERL 181 Query 188 GLPVFVKPARGGSSIGVSRVSSWDQLPAAVARARRHDPKVIVEAAISGRELECGVLEMPD 247 GLPVFVKPAR GSS+G++RV+SWD+L AVA AR HDPKV+VEAAI GRE+ECGVLE PD Sbjct 182 GLPVFVKPARAGSSVGITRVTSWDRLDEAVAAARVHDPKVLVEAAIVGREVECGVLEYPD 241 Query 248 GTLEASTLGEIRVAGVRGREDSFYDFATKYLDDAAELDVPAKVDDQVAEAIRQLAIRAFA 307 GT+ AS EIR+ V G + FYDF KYLDDA E D+PAK+DD V E +R A+ AF Sbjct 242 GTVRASLPAEIRL--VSGSAE-FYDFDAKYLDDACEFDIPAKLDDDVTERVRDQAVAAFR 298 Query 308 AIDCRGLARVDFFLTDDG-PVINEINTMPGFTTISMYPRMWAASGVDYPTLLATMIETTL 366 A+DC+GLARVDFF+ DDG PV+NE+NTMPGFT ISMYPRMWA +GVDYPTLLAT+++T L Sbjct 299 ALDCQGLARVDFFVGDDGAPVVNEVNTMPGFTPISMYPRMWAETGVDYPTLLATLVDTAL 358 Query 367 ARGVGLH 373 ARG GL Sbjct 359 ARGTGLR 365 >gi|333920842|ref|YP_004494423.1| D-alanine--D-alanine ligase [Amycolicicoccus subflavus DQS3-9A1] gi|333483063|gb|AEF41623.1| D-alanine--D-alanine ligase [Amycolicicoccus subflavus DQS3-9A1] Length=371 Score = 471 bits (1212), Expect = 8e-131, Method: Compositional matrix adjust. Identities = 234/369 (64%), Positives = 290/369 (79%), Gaps = 5/369 (1%) Query 9 RRVRVAVVFGGRSNEHAISCVSAGSILRNLDSRRFDVIAVGITPAGSWVLTDANPDALTI 68 R+RVAVVFGGRS+EH++SCVSAGS+LR++D RFDV+ +GITP G+WV +PD L I Sbjct 4 ERIRVAVVFGGRSSEHSVSCVSAGSVLRHIDRDRFDVVPIGITPDGAWVNGGTDPDELVI 63 Query 69 TNRELPQVKSGSGTELALPADPRRGGQLVSLP-PGAGEVLESVDVVFPVLHGPYGEDGTI 127 T LP+V S G ELAL A P R G ++SL AG +VDVVFPVLHGPYGEDGTI Sbjct 64 TAGSLPEV-SADGGELALSASPARRGAVISLDGDQAGGEFAAVDVVFPVLHGPYGEDGTI 122 Query 128 QGLLELAGVPYVGAGVLASAVGMDKEFTKKLLAADGLPVGAYAVLRPPRSTLHRQECERL 187 QGLLELAGVPYVGAGVLASA GMDKEFTKKLLAA+GLPVG VLRP TL ++ L Sbjct 123 QGLLELAGVPYVGAGVLASAGGMDKEFTKKLLAAEGLPVGRQVVLRPGVKTLTDEQRGYL 182 Query 188 GLPVFVKPARGGSSIGVSRVSSWDQLPAAVARARRHDPKVIVEAAISGRELECGVLEMPD 247 GLP FVKPARGGSSIG+SR+++WD L AAV ARR+DPKVI+EA + GRE+ECGVLE PD Sbjct 183 GLPAFVKPARGGSSIGISRITTWDDLDAAVDEARRYDPKVIIEAGVVGREVECGVLEFPD 242 Query 248 GTLEASTLGEIRVAGVRGRE---DSFYDFATKYLDDAAELDVPAKVDDQVAEAIRQLAIR 304 G +EAS + EIR+ G + +FYDF TKY++D E DVPA +DD + I++L++ Sbjct 243 GRVEASVVAEIRLPDTHGGDAAGGAFYDFETKYINDVTEFDVPANLDDAMTREIQRLSVA 302 Query 305 AFAAIDCRGLARVDFFLTDDGPVINEINTMPGFTTISMYPRMWAASGVDYPTLLATMIET 364 AF A+DC+G+ARVDFF+TDDGP+INE+NTMPGFT+IS+YPR+WA SG++Y L++T+I+T Sbjct 303 AFTALDCQGIARVDFFITDDGPLINEVNTMPGFTSISLYPRVWAVSGIEYQELISTLIDT 362 Query 365 TLARGVGLH 373 +ARG+GL Sbjct 363 AIARGIGLR 371 >gi|134102567|ref|YP_001108228.1| D-alanyl-alanine synthetase A [Saccharopolyspora erythraea NRRL 2338] gi|291007062|ref|ZP_06565035.1| D-alanyl-alanine synthetase A [Saccharopolyspora erythraea NRRL 2338] gi|133915190|emb|CAM05303.1| D-alanylalanine synthetase [Saccharopolyspora erythraea NRRL 2338] Length=362 Score = 459 bits (1180), Expect = 4e-127, Method: Compositional matrix adjust. Identities = 229/367 (63%), Positives = 285/367 (78%), Gaps = 10/367 (2%) Query 9 RRVRVAVVFGGRSNEHAISCVSAGSILRNLDSRRFDVIAVGITPAGSWVLTDANPDALTI 68 R+ RVAVVFGGRS EH ISCVSAGS+L +LD RF+V+ VGIT G+WVL +P+AL I Sbjct 4 RKTRVAVVFGGRSTEHGISCVSAGSVLAHLDRDRFEVVPVGITKEGAWVLAGDDPEALEI 63 Query 69 TNRELPQVKSGSGTELALPADPRRGGQLVSLPPG-AGEVLESVDVVFPVLHGPYGEDGTI 127 +R P++ SG +ALP DP R L+ L PG GEVL SVDVVFPVLHG +GEDGTI Sbjct 64 QDRRTPEITSGKA--VALPGDPTR--DLMYLEPGRGGEVLSSVDVVFPVLHGAFGEDGTI 119 Query 128 QGLLELAGVPYVGAGVLASAVGMDKEFTKKLLAADGLPVGAYAVLRPPRSTLHRQECERL 187 QGLLE+AGVPY G GVL+SAV MDKE+TKKLLAA+GL VG Y VLR +STL +Q+ ERL Sbjct 120 QGLLEMAGVPYAGPGVLSSAVAMDKEYTKKLLAAEGLAVGTYEVLRRDQSTLDQQQRERL 179 Query 188 GLPVFVKPARGGSSIGVSRVSSWDQLPAAVARARRHDPKVIVEAAISGRELECGVLEMPD 247 GLPVFVKPAR GSS+G+++V+ L A+A ARR DPKVI+E+A++GRE+ECGVLE PD Sbjct 180 GLPVFVKPARAGSSLGITKVTDHADLDDAIAEARRTDPKVIIESAVTGREVECGVLEFPD 239 Query 248 GTLEASTLGEIRVAGVRGREDSFYDFATKYLDDAAELDVPAKVDDQVAEAIRQLAIRAFA 307 G +EAS E+RV G + ++YD+ +KYLDD E D+PAK+ D E +R+ A+ AF Sbjct 240 GRVEASLPAELRVTG----DSTWYDYESKYLDDVTEFDIPAKIGDDAIERMREAAVTAFR 295 Query 308 AIDCRGLARVDFFLTDDGP-VINEINTMPGFTTISMYPRMWAASGVDYPTLLATMIETTL 366 A++C+GLARVDFF+ DDG ++NE+NTMPGFT IS+YPRMWA +GVDYPTLL+T+IET + Sbjct 296 ALECQGLARVDFFVADDGELIVNEVNTMPGFTAISLYPRMWAQTGVDYPTLLSTLIETAI 355 Query 367 ARGVGLH 373 ARG GL Sbjct 356 ARGTGLR 362 >gi|302525004|ref|ZP_07277346.1| D-alanylalanine synthetase [Streptomyces sp. AA4] gi|302433899|gb|EFL05715.1| D-alanylalanine synthetase [Streptomyces sp. AA4] Length=365 Score = 449 bits (1156), Expect = 3e-124, Method: Compositional matrix adjust. Identities = 230/366 (63%), Positives = 284/366 (78%), Gaps = 7/366 (1%) Query 10 RVRVAVVFGGRSNEHAISCVSAGSILRNLDSRRFDVIAVGITPAGSWVLTDANPDALTIT 69 ++RVAVVFGGRS+EH ISC+SAGS++ NLD RF+V+ VG+TP+G WVL +P L+I Sbjct 5 KIRVAVVFGGRSSEHTISCLSAGSVISNLDPDRFEVLPVGVTPSGGWVLGTGDPQQLSIR 64 Query 70 NRELPQVKSGSGTELALPADPRRGGQLVSLPPG-AGEVLESVDVVFPVLHGPYGEDGTIQ 128 RELP V+SG L L DP +L ++ PG A EVL +VDVVFPVLHG +GEDGTIQ Sbjct 65 GRELPSVESGRA--LVLAGDPT-SRELRTVDPGQATEVLGTVDVVFPVLHGAFGEDGTIQ 121 Query 129 GLLELAGVPYVGAGVLASAVGMDKEFTKKLLAADGLPVGAYAVLRPPRSTLHRQECERLG 188 GLLELA +PYVG GV ASA MDKE+ KKLLAA+GLPVG YA LR +STL + ERLG Sbjct 122 GLLELADLPYVGPGVFASAAAMDKEYAKKLLAAEGLPVGTYAALRRGQSTLAEADRERLG 181 Query 189 LPVFVKPARGGSSIGVSRVSSWDQLPAAVARARRHDPKVIVEAAISGRELECGVLEMPDG 248 LPVFVKP+R GSS+G+SRV+ W L AA+ ARR DPKV+VEAA+ GRE+ECGVLE PDG Sbjct 182 LPVFVKPSRAGSSVGISRVADWADLDAAIELARRTDPKVLVEAAVRGREVECGVLEFPDG 241 Query 249 TLEASTLGEIRVAGVRGREDSFYDFATKYLDDAAELDVPAKVDDQVAEAIRQLAIRAFAA 308 +EAS EIRV + ED++YDF TKYL + AELD+PAK+DD + + +R +A+ AF A Sbjct 242 RVEASLPAEIRV--LAEGEDAWYDFETKYLGEDAELDIPAKLDDALTDRLRAMAVEAFRA 299 Query 309 IDCRGLARVDFFLTDDGP-VINEINTMPGFTTISMYPRMWAASGVDYPTLLATMIETTLA 367 +DC+GLARVDFF+T++G VINE+NTMPGFTT S YP+MW +GVDYPTLL+T+I+T LA Sbjct 300 LDCQGLARVDFFVTEEGDLVINEVNTMPGFTTKSAYPKMWEVTGVDYPTLLSTLIDTALA 359 Query 368 RGVGLH 373 RG GL Sbjct 360 RGTGLR 365 >gi|257054969|ref|YP_003132801.1| D-alanyl-alanine synthetase A [Saccharomonospora viridis DSM 43017] gi|256584841|gb|ACU95974.1| D-alanine--D-alanine ligase [Saccharomonospora viridis DSM 43017] Length=365 Score = 441 bits (1135), Expect = 7e-122, Method: Compositional matrix adjust. Identities = 225/366 (62%), Positives = 270/366 (74%), Gaps = 5/366 (1%) Query 9 RRVRVAVVFGGRSNEHAISCVSAGSILRNLDSRRFDVIAVGITPAGSWVLTDANPDALTI 68 R+ RVAVVFGGRS EH ISCVSAGSI+ NLD RF+V+ +GIT G WVL +P+ L I Sbjct 4 RKTRVAVVFGGRSTEHTISCVSAGSIMANLDPDRFEVVPIGITQEGGWVLGTNDPEQLRI 63 Query 69 TNRELPQVKSGSGTELALPADPRRGGQLVSLPPGAGEVLESVDVVFPVLHGPYGEDGTIQ 128 RELP V+ G L L DP GG L EVL VDVVFP LHG +GEDGTIQ Sbjct 64 KGRELPVVEHGK--TLVLAGDPTTGGVLSLTAGEPAEVLSGVDVVFPALHGAFGEDGTIQ 121 Query 129 GLLELAGVPYVGAGVLASAVGMDKEFTKKLLAADGLPVGAYAVLRPPRSTLHRQECERLG 188 GLLELA +PYVG+GV ASA MDKE+ KKLLAA+GL VG YAV+R + TL +E ERLG Sbjct 122 GLLELADIPYVGSGVFASAAAMDKEYAKKLLAAEGLEVGRYAVVRRGQDTLPAEERERLG 181 Query 189 LPVFVKPARGGSSIGVSRVSSWDQLPAAVARARRHDPKVIVEAAISGRELECGVLEMPDG 248 LPVFVKPAR GSSIG+SRV+ W QL AA+A AR+ DPKV+VEA GRE+ECGVLE DG Sbjct 182 LPVFVKPARAGSSIGISRVTDWSQLDAAIAHARQTDPKVLVEAETVGREVECGVLEFADG 241 Query 249 TLEASTLGEIRVAGVRGREDSFYDFATKYLDDAAELDVPAKVDDQVAEAIRQLAIRAFAA 308 +EAS EIRV + D++YDF TKYL + AELD+PAK+DD + E +R +A+RAF A Sbjct 242 RVEASFPSEIRV--LSDDADAWYDFETKYLGEDAELDIPAKLDDTITERLRDMAVRAFTA 299 Query 309 IDCRGLARVDFFLTDDGPV-INEINTMPGFTTISMYPRMWAASGVDYPTLLATMIETTLA 367 ++C+GLARVDFF+ DG + +NE+NTMPGFT S YP+MW +G+DYPTLL T++ET LA Sbjct 300 LECQGLARVDFFVGPDGTLTVNEVNTMPGFTPTSAYPKMWEVTGIDYPTLLTTLVETALA 359 Query 368 RGVGLH 373 RG GL Sbjct 360 RGTGLR 365 >gi|300783664|ref|YP_003763955.1| D-alanine-D-alanine ligase [Amycolatopsis mediterranei U32] gi|299793178|gb|ADJ43553.1| D-alanine-D-alanine ligase [Amycolatopsis mediterranei U32] gi|340525054|gb|AEK40259.1| D-alanyl-alanine synthetase A [Amycolatopsis mediterranei S699] Length=364 Score = 436 bits (1122), Expect = 3e-120, Method: Compositional matrix adjust. Identities = 222/366 (61%), Positives = 276/366 (76%), Gaps = 7/366 (1%) Query 9 RRVRVAVVFGGRSNEHAISCVSAGSILRNLDSRRFDVIAVGITPAGSWVLTDANPDALTI 68 ++RVAVVFGGRS+EH ISC+SAGS+L +LD RF+ + VGIT G WVL + L + Sbjct 3 EKIRVAVVFGGRSSEHTISCLSAGSVLGHLDPERFEAVPVGITREGRWVLGSGDSAQLAV 62 Query 69 TNRELPQVKSGSGTELALPADPRRGGQLVSLPPG-AGEVLESVDVVFPVLHGPYGEDGTI 127 RELP V G G L L DP G LV++ G E+L VDVVFPVLHG +GEDGTI Sbjct 63 RGRELPSVDDGQG--LVLAGDPSSQG-LVAVEAGRESELLSRVDVVFPVLHGAFGEDGTI 119 Query 128 QGLLELAGVPYVGAGVLASAVGMDKEFTKKLLAADGLPVGAYAVLRPPRSTLHRQECERL 187 QGLLELAG+PYVG GVLASA MDKE KKLLAA+GLPVG ++ L+ +STL + + E+L Sbjct 120 QGLLELAGIPYVGPGVLASAAAMDKETAKKLLAAEGLPVGTFSALKRGQSTLEQTDREKL 179 Query 188 GLPVFVKPARGGSSIGVSRVSSWDQLPAAVARARRHDPKVIVEAAISGRELECGVLEMPD 247 GLPVFVKP+R GSS+G+SRV+ W L AA+A AR DPKV+VEAA+ GRE+ECGVLE PD Sbjct 180 GLPVFVKPSRAGSSVGISRVADWAGLDAAIALARATDPKVLVEAAVVGREVECGVLEFPD 239 Query 248 GTLEASTLGEIRVAGVRGREDSFYDFATKYLDDAAELDVPAKVDDQVAEAIRQLAIRAFA 307 G +EAS EIRV + E+++YDF TKYL D AELD+PAK+DD + E +R +A+ AF Sbjct 240 GHVEASLPAEIRV--LSEDENAWYDFETKYLGDDAELDIPAKLDDALTEKLRAMAVEAFR 297 Query 308 AIDCRGLARVDFFLTDDGP-VINEINTMPGFTTISMYPRMWAASGVDYPTLLATMIETTL 366 A+DC+GLARVDFF+T+D +INE+NTMPGFTT S YP+MW +G+DYPTLL T++ET + Sbjct 298 ALDCQGLARVDFFVTEDHQLIINEVNTMPGFTTKSAYPKMWEVTGMDYPTLLTTLVETAI 357 Query 367 ARGVGL 372 ARG GL Sbjct 358 ARGTGL 363 >gi|296140535|ref|YP_003647778.1| D-alanine/D-alanine ligase [Tsukamurella paurometabola DSM 20162] gi|296028669|gb|ADG79439.1| D-alanine/D-alanine ligase [Tsukamurella paurometabola DSM 20162] Length=362 Score = 432 bits (1112), Expect = 4e-119, Method: Compositional matrix adjust. Identities = 233/366 (64%), Positives = 281/366 (77%), Gaps = 8/366 (2%) Query 8 DRRVRVAVVFGGRSNEHAISCVSAGSILRNLDSRRFDVIAVGITPAGSWVLTDANPDALT 67 D R++VAVVFGGRS+EHA+SCVSAGSIL +LD R++V+ VGIT +GSWVL+DA+ +L Sbjct 3 DSRIKVAVVFGGRSSEHAVSCVSAGSILGHLDPARYEVVPVGITQSGSWVLSDADAQSLR 62 Query 68 ITNRELPQVKSGSGTELALPADPRRGGQLVSLPP-GAGEVLESVDVVFPVLHGPYGEDGT 126 +R LP V G T+LAL G +LVS+ AG VL SVDVVFPVLHGPYGEDGT Sbjct 63 FADRALPSVPEGP-TDLAL----LPGAELVSVSSDAAGSVLGSVDVVFPVLHGPYGEDGT 117 Query 127 IQGLLELAGVPYVGAGVLASAVGMDKEFTKKLLAADGLPVGAYAVLRPPRSTLHRQECER 186 +QGLLE+AGVPYVGAGVLASA GMDKEF KKLLAADGLPVG + VLR + + + R Sbjct 118 LQGLLEMAGVPYVGAGVLASAAGMDKEFAKKLLAADGLPVGDFHVLRQRETEVPPEVLHR 177 Query 187 LGLPVFVKPARGGSSIGVSRVSSWDQLPAAVARARRHDPKVIVEAAISGRELECGVLEMP 246 LGLP+FVKPARGGSSIG++RV+ LPAA+A ARR DPKVI+EAA+ GRE+E GVLE P Sbjct 178 LGLPLFVKPARGGSSIGITRVTDLAALPAAIAEARRWDPKVIIEAAVIGREVEIGVLERP 237 Query 247 DGTLEASTLGEIRVAGVRGREDSFYDFATKYLDDAAELDVPAKVDDQVAEAIRQLAIRAF 306 DGT+ AS + EI +A E +FYDF TKYLDD A+ VPA + ++ AI +LA+RAF Sbjct 238 DGTVHASAIAEIEMAA--DAEHAFYDFETKYLDDRAQYTVPADLTEEQTSAIAELAVRAF 295 Query 307 AAIDCRGLARVDFFLTDDGPVINEINTMPGFTTISMYPRMWAASGVDYPTLLATMIETTL 366 A D +GLARVDFF T +GPVINE+NTMPGFT+ SMYPRMWA SG+ Y LL+ +I+T L Sbjct 296 HAFDGQGLARVDFFQTAEGPVINEVNTMPGFTSTSMYPRMWAESGIGYAELLSLLIDTAL 355 Query 367 ARGVGL 372 ARG GL Sbjct 356 ARGTGL 361 >gi|256379981|ref|YP_003103641.1| D-alanyl-alanine synthetase A [Actinosynnema mirum DSM 43827] gi|255924284|gb|ACU39795.1| D-alanine/D-alanine ligase [Actinosynnema mirum DSM 43827] Length=355 Score = 414 bits (1063), Expect = 2e-113, Method: Compositional matrix adjust. Identities = 211/366 (58%), Positives = 271/366 (75%), Gaps = 15/366 (4%) Query 9 RRVRVAVVFGGRSNEHAISCVSAGSILRNLDSRRFDVIAVGITPAGSWVLTDANPDALTI 68 R+ +VAVVFGGRS+EH +SCVSAGS+L +LD RF+V+ VGIT G+WV+ + AL I Sbjct 4 RKTKVAVVFGGRSSEHTVSCVSAGSVLAHLDRERFEVVPVGITRQGAWVVGSGDLAALEI 63 Query 69 TNRELPQVKSGSGTELALPADPRRGGQLVSLPPGAGEVLESVDVVFPVLHGPYGEDGTIQ 128 +R++P V + P GG+L ++ P + L+ VDVVFP+LHG +GEDGT+Q Sbjct 64 RDRQMPTVDA---------LVPVSGGELTTVSPDSA--LDGVDVVFPLLHGAWGEDGTVQ 112 Query 129 GLLELAGVPYVGAGVLASAVGMDKEFTKKLLAADGLPVGAYAVLRPPRSTLHRQECERLG 188 GLLELA +PYVG GVLASA MDKEFTK +L A GL VG++AVLR ++TL + +RLG Sbjct 113 GLLELADLPYVGPGVLASAAAMDKEFTKTILRAAGLEVGSFAVLRRDQATLSEADRDRLG 172 Query 189 LPVFVKPARGGSSIGVSRVSSWDQLPAAVARARRHDPKVIVEAAISGRELECGVLEMPDG 248 LP+FVKPAR GSS+G+++V+ W L AA+A AR+ DPKVI+EAA++GRE+ECGVLE+PDG Sbjct 173 LPLFVKPARAGSSVGITKVTDWADLDAAIAFARQTDPKVIIEAAVTGREVECGVLELPDG 232 Query 249 TLEASTLGEIRVAGVRGREDSFYDFATKYLDDAAELDVPAKVDDQVAEAIRQLAIRAFAA 308 +EAS E+RV G G D +YDF KYLDD E D+PAK+ D E +R LA+ AF A Sbjct 233 RVEASLPAELRVVG--GGVD-WYDFDAKYLDDVCEFDIPAKLADDTTERLRALAVEAFRA 289 Query 309 IDCRGLARVDFFLTDDGP-VINEINTMPGFTTISMYPRMWAASGVDYPTLLATMIETTLA 367 +DC+GLARVDFF+T+DG V+NEINTMPGFT ISMYPRMW +G Y LL T++ET +A Sbjct 290 LDCQGLARVDFFVTEDGGLVVNEINTMPGFTPISMYPRMWEVTGTSYRDLLTTLVETAIA 349 Query 368 RGVGLH 373 RG GL Sbjct 350 RGTGLR 355 >gi|325000509|ref|ZP_08121621.1| D-alanyl-alanine synthetase A [Pseudonocardia sp. P1] Length=356 Score = 411 bits (1056), Expect = 1e-112, Method: Compositional matrix adjust. Identities = 218/364 (60%), Positives = 275/364 (76%), Gaps = 14/364 (3%) Query 10 RVRVAVVFGGRSNEHAISCVSAGSILRNLDSRRFDVIAVGITPAGSWVLTDANPDALTIT 69 RVRVAVVFGGRS+EHAISCVSAGS+L +LD RF+V+ VGI+ G+WV ++P L I+ Sbjct 5 RVRVAVVFGGRSSEHAISCVSAGSVLTHLDPERFEVVPVGISRDGAWVTGPSDPRELGIS 64 Query 70 NRELPQVKSGSGTELALPADPRRGGQLVSLPPGAGEVLESVDVVFPVLHGPYGEDGTIQG 129 RELP+V G+ L LP +P RG L+ L AGE L VDVVFP+LHG +GEDGTIQG Sbjct 65 GRELPEV-DGTSDALVLPGEPGRG--LIRL--DAGEALSQVDVVFPILHGAFGEDGTIQG 119 Query 130 LLELAGVPYVGAGVLASAVGMDKEFTKKLLAADGLPVGAYAVLRPPRSTLHRQECERLGL 189 LLE+AG+PYVGAGVLASAVGMDKEF KKLL A+GL V VLR P + + + +RLGL Sbjct 120 LLEMAGLPYVGAGVLASAVGMDKEFAKKLLRAEGLNVADGIVLR-PGTDIGFADRDRLGL 178 Query 190 PVFVKPARGGSSIGVSRVSSWDQLPAAVARARRHDPKVIVEAAISGRELECGVLEMPDGT 249 P+FVKPAR GSS+GV+RV+ L AA+A AR HDPKV+VE+A+ GRE+EC VLE PDG+ Sbjct 179 PLFVKPARAGSSMGVTRVTDPAGLDAAIAEAREHDPKVLVESAVPGREVECAVLEFPDGS 238 Query 250 LEASTLGEIRVAGVRGREDSFYDFATKYLDDAAELDVPAKVDDQVAEAIRQLAIRAFAAI 309 + AS E+R G FYDF +KYL D +EL++PAK+DD++ +++R A+ AF A+ Sbjct 239 VRASLPAELRYNG------EFYDFESKYL-DVSELEIPAKLDDEITDSVRWKAVTAFRAL 291 Query 310 DCRGLARVDFFLTDDGPV-INEINTMPGFTTISMYPRMWAASGVDYPTLLATMIETTLAR 368 D +GLARVDFF+TDDG + +NE+NTMPGFT S +P+MWA +G+DY LL TM+ET LAR Sbjct 292 DVQGLARVDFFVTDDGHITVNEVNTMPGFTPSSAFPKMWAVTGLDYGELLTTMVETALAR 351 Query 369 GVGL 372 G GL Sbjct 352 GTGL 355 >gi|330466252|ref|YP_004403995.1| D-alanine--D-alanine ligase [Verrucosispora maris AB-18-032] gi|328809223|gb|AEB43395.1| D-alanine--D-alanine ligase [Verrucosispora maris AB-18-032] Length=368 Score = 405 bits (1042), Expect = 5e-111, Method: Compositional matrix adjust. Identities = 215/368 (59%), Positives = 262/368 (72%), Gaps = 9/368 (2%) Query 10 RVRVAVVFGGRSNEHAISCVSAGSILRNLDSRRFDVIAVGITPAGSWVLTDANPDALTIT 69 + RVA+VFGGRS EH ISCVSAGS+L LD F+V+ VGIT AG WVLT +P L I Sbjct 6 KTRVAIVFGGRSPEHGISCVSAGSVLGALDPDEFEVVPVGITRAGQWVLTSGDPTELAIN 65 Query 70 NRELPQVKSGSGTELALPADPRRGGQLVSLPPGAGEVLESVDVVFPVLHGPYGEDGTIQG 129 +R LP++ + SG ++ L ADP G LV P L +VDVVFPVLHG YGEDGTIQG Sbjct 66 SRRLPEITAESGADIVLRADPTGSGLLVLDPTEGPRALANVDVVFPVLHGAYGEDGTIQG 125 Query 130 LLELAGVPYVGAGVLASAVGMDKEFTKKLLAADGLPVGAYAVLRPPRSTLHRQECERLGL 189 +LE+AG+PYVGA V ASA MDKEFTKK+ AA+G+P+G YAVLR TL ++ +RLGL Sbjct 126 MLEMAGIPYVGAKVFASAAAMDKEFTKKICAAEGIPIGPYAVLR-SGMTLSEEDKQRLGL 184 Query 190 PVFVKPARGGSSIGVSRVSSWDQLPAAVARARRHDPKVIVEAAISGRELECGVLE-MPDG 248 PVFVKP+R GSS GVS+VS W L AA+A AR D KV+VE AI GRE+ECGVLE G Sbjct 185 PVFVKPSRAGSSFGVSKVSDWADLEAAIAIAREIDSKVLVEGAIIGREIECGVLEGEAGG 244 Query 249 TLEASTLGEIRVAGVRGREDSFYDFATKYLD--DAAELDVPAKVDDQVAEAIRQLAIRAF 306 T EAS L E+RV G + FYDF KY+D A E DVPA + ++VA +R A+RAF Sbjct 245 TPEASVLAEVRVVG----DYDFYDFEAKYIDAESACEYDVPADLPERVARQVRDYAVRAF 300 Query 307 AAIDCRGLARVDFFLTDDGPV-INEINTMPGFTTISMYPRMWAASGVDYPTLLATMIETT 365 A+DC GLAR DFF+T + + +NEINTMPGFT SM+PRMWAASG++YP L+ +I T Sbjct 301 TALDCAGLARADFFVTPELDIYLNEINTMPGFTPTSMFPRMWAASGLEYPKLVDRLIRTA 360 Query 366 LARGVGLH 373 L RG G + Sbjct 361 LTRGTGHY 368 >gi|237785790|ref|YP_002906495.1| D-alanyl-alanine synthetase A [Corynebacterium kroppenstedtii DSM 44385] gi|237758702|gb|ACR17952.1| D-alanine-D-alanine ligase [Corynebacterium kroppenstedtii DSM 44385] Length=412 Score = 405 bits (1041), Expect = 5e-111, Method: Compositional matrix adjust. Identities = 202/358 (57%), Positives = 259/358 (73%), Gaps = 6/358 (1%) Query 10 RVRVAVVFGGRSNEHAISCVSAGSILRNLDSRRFDVIAVGITPAGSWVLTDANPDALTIT 69 R+RVAVV+GGRS+EH+ISCVSAG+++ +LD R+ V+ +GIT G WV+ ++P L+I Sbjct 54 RIRVAVVYGGRSSEHSISCVSAGAVISHLDPDRYQVVPIGITRDGRWVVGSSDPKELSIR 113 Query 70 NRELPQVKSGSGTELALPADPRRGGQLVSLP-PGAGEVLESVDVVFPVLHGPYGEDGTIQ 128 R+LP+VK+G T L+L DP+ G+ V P G+V VDV+FPVLHG +GEDGT+Q Sbjct 114 ERQLPEVKAG--TSLSLSLDPQHAGRFVYADGPDVGQVFADVDVIFPVLHGGFGEDGTVQ 171 Query 129 GLLELAGVPYVGAGVLASAVGMDKEFTKKLLAADGLPVGAYAVLRPPRSTLHRQECERLG 188 GL ++A VPYVGAGVLASA MDKEFTKKL AA+GLP+G VLR RS L +E LG Sbjct 172 GLFDMASVPYVGAGVLASAASMDKEFTKKLAAAEGLPIGRDVVLRETRS-LTEEEKNLLG 230 Query 189 LPVFVKPARGGSSIGVSRVSSWDQLPAAVARARRHDPKVIVEAAISGRELECGVLEMPDG 248 LPVFVKPARGGSSIG+S+V WD+L A+ AR+HD KVIVE+ I G E+ECGVL+ PDG Sbjct 231 LPVFVKPARGGSSIGISKVDQWDELDDALDLARQHDSKVIVESMIVGTEVECGVLQRPDG 290 Query 249 TLEASTLGEIRVAGVRGREDSFYDFATKYLDDAAELDVPAKVDDQVAEAIRQLAIRAFAA 308 T+EAS ++ ++ FY F TKYLD+ +P DD IR+LA+ F A Sbjct 291 TVEASLPAQLE--DTESGDEGFYGFDTKYLDNVITAQIPPHFDDDTIRHIRELAVETFHA 348 Query 309 IDCRGLARVDFFLTDDGPVINEINTMPGFTTISMYPRMWAASGVDYPTLLATMIETTL 366 +DC GLAR+DFF+TD GPV+NEINTMPGFT ISMYP+M+ A G+DYP LL +I+ + Sbjct 349 LDCEGLARIDFFVTDRGPVLNEINTMPGFTPISMYPQMFGAMGIDYPDLLDLLIQRAM 406 >gi|145593823|ref|YP_001158120.1| D-alanine--D-alanine ligase [Salinispora tropica CNB-440] gi|145303160|gb|ABP53742.1| D-alanine--D-alanine ligase [Salinispora tropica CNB-440] Length=368 Score = 401 bits (1031), Expect = 9e-110, Method: Compositional matrix adjust. Identities = 208/366 (57%), Positives = 262/366 (72%), Gaps = 9/366 (2%) Query 10 RVRVAVVFGGRSNEHAISCVSAGSILRNLDSRRFDVIAVGITPAGSWVLTDANPDALTIT 69 ++RVAVVFGGRS EH ISCVSAGS+L LD ++V+ VGI+ AG WVLT ++P L I+ Sbjct 6 KIRVAVVFGGRSPEHGISCVSAGSVLAALDPDEYEVVPVGISRAGQWVLTGSDPAELAIS 65 Query 70 NRELPQVKSGSGTELALPADPRRGGQLVSLPPGAGEVLESVDVVFPVLHGPYGEDGTIQG 129 R LP+V + SG + L ADP G +V L VDVVFPVLHG YGEDG+IQG Sbjct 66 ARRLPEVTAESGAAIMLNADPSHSGLMVLDATAGPRALADVDVVFPVLHGAYGEDGSIQG 125 Query 130 LLELAGVPYVGAGVLASAVGMDKEFTKKLLAADGLPVGAYAVLRPPRSTLHRQECERLGL 189 +LE+AG+PYVGA V ASA MDKEFTKKL AA+G+P+G Y VLR TL Q+ +RLGL Sbjct 126 MLEMAGIPYVGANVFASAAAMDKEFTKKLCAAEGIPIGPYVVLRSGM-TLTEQDKQRLGL 184 Query 190 PVFVKPARGGSSIGVSRVSSWDQLPAAVARARRHDPKVIVEAAISGRELECGVLEMPDGT 249 PVFVKP+R GSS G++++S W +L AAVA AR+ D KV+VEAA+ GRE+ECGVLE G Sbjct 185 PVFVKPSRAGSSFGITKISDWAELDAAVATARQIDSKVLVEAAVVGREIECGVLEGEAGG 244 Query 250 L-EASTLGEIRVAGVRGREDSFYDFATKYLD--DAAELDVPAKVDDQVAEAIRQLAIRAF 306 + EAS L E+RV G E FYDF KY+D A E D+PA + ++V +++ A+RAF Sbjct 245 VPEASVLAEVRVVG----EYDFYDFEAKYIDAESACEYDIPAGLSERVTRQVQEYAVRAF 300 Query 307 AAIDCRGLARVDFFLTDDGPV-INEINTMPGFTTISMYPRMWAASGVDYPTLLATMIETT 365 A+DC GLAR DFF+T + + +NEINTMPGFT SM+PRMWAASG++YP L+ +I T Sbjct 301 TALDCAGLARADFFVTPELDIYLNEINTMPGFTPSSMFPRMWAASGLEYPKLVNRLIRTA 360 Query 366 LARGVG 371 L RG G Sbjct 361 LQRGAG 366 >gi|159036808|ref|YP_001536061.1| D-alanine--D-alanine ligase [Salinispora arenicola CNS-205] gi|157915643|gb|ABV97070.1| D-alanine--D-alanine ligase [Salinispora arenicola CNS-205] Length=360 Score = 398 bits (1022), Expect = 8e-109, Method: Compositional matrix adjust. Identities = 212/363 (59%), Positives = 261/363 (72%), Gaps = 9/363 (2%) Query 13 VAVVFGGRSNEHAISCVSAGSILRNLDSRRFDVIAVGITPAGSWVLTDANPDALTITNRE 72 +AVVFGGRS EH ISCVSAGS+L LD ++V+ VGI+ AG WVLT + L IT+R Sbjct 1 MAVVFGGRSPEHGISCVSAGSVLAALDPDEYEVVPVGISRAGQWVLTGGDSSQLAITDRR 60 Query 73 LPQVKSGSGTELALPADPRRGGQLVSLPPGAGEVLESVDVVFPVLHGPYGEDGTIQGLLE 132 LP+V + SGT + L ADP GG LV P L VDVVFPVLHG YGEDGTIQG+LE Sbjct 61 LPEVTAESGTAVVLNADPSSGGLLVLDPAEGSRALADVDVVFPVLHGAYGEDGTIQGMLE 120 Query 133 LAGVPYVGAGVLASAVGMDKEFTKKLLAADGLPVGAYAVLRPPRSTLHRQECERLGLPVF 192 +AG+PYVGA V ASA MDKEFTKKL AA+G+PVG YAVLR TL Q+ +RLGLPVF Sbjct 121 MAGIPYVGANVFASAAAMDKEFTKKLCAAEGIPVGPYAVLRSGM-TLTEQDKQRLGLPVF 179 Query 193 VKPARGGSSIGVSRVSSWDQLPAAVARARRHDPKVIVEAAISGRELECGVLEMPDGTL-E 251 VKP+R GSS G++RV+ W L AVA AR+ DPKV+VE+A+ GRE+ECGVLE G + E Sbjct 180 VKPSRAGSSFGITRVTDWADLDDAVANARKIDPKVLVESAVIGREIECGVLEAEAGGVPE 239 Query 252 ASTLGEIRVAGVRGREDSFYDFATKYLD-DAA-ELDVPAKVDDQVAEAIRQLAIRAFAAI 309 AS L E+RV G + FYDF KY+D DAA E D+PA + ++V +++ A+RAF A+ Sbjct 240 ASALAEVRVVG----DYDFYDFEAKYIDADAACEYDIPADLPERVTRQVQEYAVRAFTAL 295 Query 310 DCRGLARVDFFLTDDGPV-INEINTMPGFTTISMYPRMWAASGVDYPTLLATMIETTLAR 368 DC GLAR DFF+T + V +NE+NTMPGFT SM+PRMWAASG++Y L+ +I T L Sbjct 296 DCAGLARADFFVTPELDVYLNEVNTMPGFTPTSMFPRMWAASGLEYQKLVNRLIRTALNG 355 Query 369 GVG 371 G G Sbjct 356 GAG 358 >gi|319951163|ref|ZP_08025008.1| D-alanyl-alanine synthetase A [Dietzia cinnamea P4] gi|319435179|gb|EFV90454.1| D-alanyl-alanine synthetase A [Dietzia cinnamea P4] Length=368 Score = 398 bits (1022), Expect = 9e-109, Method: Compositional matrix adjust. Identities = 211/369 (58%), Positives = 266/369 (73%), Gaps = 12/369 (3%) Query 10 RVRVAVVFGGRSNEHAISCVSAGSILRNLDSRRFDVIAVGITPAGSWVLTDANPDALTIT 69 R+ VAV++GGRS+EH++SCVSAG+++ +LD R++VI VGIT AG+W L + L I Sbjct 3 RITVAVLYGGRSSEHSVSCVSAGAVMGHLDRSRYEVIPVGITEAGAWTLGSDDTADLRIA 62 Query 70 NRELPQVKSGS-GTELALPADPRRGGQLVSLPPG--AGEVLESVDVVFPVLHGPYGEDGT 126 +R +P V +G L L D R ++ G AG+ + VDVVFPV+HG + EDGT Sbjct 63 DRIMPVVDAGRPRVALGLSTDDR---GVLRFADGDRAGQEIARVDVVFPVMHGTHAEDGT 119 Query 127 IQGLLELAGVPYVGAGVLASAVGMDKEFTKKLLAADGLPVGAYAVLRPPRSTLHRQECER 186 IQGLLEL+G+PYVG GV ASA GMDKEFTK +L A GLP+G VLRP +TL + +R Sbjct 120 IQGLLELSGIPYVGPGVFASAAGMDKEFTKVVLGAAGLPIGRQVVLRPGTATLSPADRDR 179 Query 187 LGLPVFVKPARGGSSIGVSRVSSWDQLPAAVARARRHDPKVIVEAAISGRELECGVLEMP 246 LGLP+FVKPARGGSSIG+++VS L AA+A ARR D KVIVEAAI GRE+ECGVLE P Sbjct 180 LGLPLFVKPARGGSSIGITKVSRAADLDAAIAEARRFDEKVIVEAAIVGREIECGVLEYP 239 Query 247 DGTLEASTLGEIRV----AGVRGRE--DSFYDFATKYLDDAAELDVPAKVDDQVAEAIRQ 300 DG +EAS E+ + GV G D+FYDF TKYLDD D+PA + + E +R Sbjct 240 DGRVEASLPAELHIPGEPTGVEGETEGDAFYDFDTKYLDDVTTFDLPADLPAEQTEQLRT 299 Query 301 LAIRAFAAIDCRGLARVDFFLTDDGPVINEINTMPGFTTISMYPRMWAASGVDYPTLLAT 360 LA+ AF A+D RGL+RVDFF+T +GPVINE+NTMPGFT ISMYP+MWAA+GVDY +LL T Sbjct 300 LAVEAFHALDARGLSRVDFFVTAEGPVINEVNTMPGFTPISMYPQMWAATGVDYESLLDT 359 Query 361 MIETTLARG 369 +I T +ARG Sbjct 360 LIRTAIARG 368 >gi|258651717|ref|YP_003200873.1| D-alanine/D-alanine ligase [Nakamurella multipartita DSM 44233] gi|258554942|gb|ACV77884.1| D-alanine/D-alanine ligase [Nakamurella multipartita DSM 44233] Length=367 Score = 397 bits (1021), Expect = 1e-108, Method: Compositional matrix adjust. Identities = 229/371 (62%), Positives = 269/371 (73%), Gaps = 17/371 (4%) Query 10 RVRVAVVFGGRSNEHAISCVSAGSILRNLDSRRFDVIAVGITPAGSWVLTDANPDALTIT 69 R+RVAVVFGGRS EH +SC+SA +L N+D+ FDV AVGITPAG W+ D P A+ T Sbjct 5 RIRVAVVFGGRSGEHPVSCISAAGVLANIDTDLFDVTAVGITPAGRWLQMD--PAAIPTT 62 Query 70 N-RELPQVKSGSGTELALPADPRRGGQLVSLPPGAG-EVLESVDVVFPVLHGPYGEDGTI 127 LP+V +GS +ALP DP LVS+ P + V+VVFPVLHGPYGEDGTI Sbjct 63 GGPTLPEVSTGSA--VALPVDPT-AAALVSIDPSVDRSAVVDVEVVFPVLHGPYGEDGTI 119 Query 128 QGLLELAGVPYVGAGVLASAVGMDKEFTKKLLAADGLPVGAYAVLRPPRSTLHRQECERL 187 QGLLELAGVPYVGAGVLASA MDKEFTKKLLAA+GLPVG + VLRP TL ++ +RL Sbjct 120 QGLLELAGVPYVGAGVLASAAAMDKEFTKKLLAAEGLPVGDWVVLRPGTPTLTAEQKQRL 179 Query 188 GLPVFVKPARGGSSIGVSRVSSWDQLPAAVARARRHDPKVIVEAAISGRELECGVLEMPD 247 GLPVFVKPAR GSS+GVSRV+ W +L A+A AR DPKV+VEAA+ GRE+ECGVLE PD Sbjct 180 GLPVFVKPARAGSSLGVSRVAEWAELDRAIAIARETDPKVLVEAAVVGREVECGVLEHPD 239 Query 248 GTLEASTLGEIRVAGVRGREDSFYDFATKYLDD-AAELDVPAKVDDQVAEAIRQLAIRAF 306 G +EAS EI V G G E FYDF KYLDD AA D+PA + D+V I +L+ RAF Sbjct 240 GRIEASPPAEIHVGG--GYE--FYDFDAKYLDDTAASFDIPADLPDEVTARIHELSRRAF 295 Query 307 AAIDCRGLARVDFFLTDDGP-----VINEINTMPGFTTISMYPRMWAASGVDYPTLLATM 361 AA+D +GLARVDFF+ DG VINE+NT+PGFT ISMYP MWA +GV Y L+ + Sbjct 296 AALDAQGLARVDFFVRPDGDLADRVVINEVNTLPGFTPISMYPAMWAKAGVSYRDLITVL 355 Query 362 IETTLARGVGL 372 I T LARG GL Sbjct 356 IRTALARGTGL 366 >gi|336179523|ref|YP_004584898.1| D-alanine--D-alanine ligase [Frankia symbiont of Datisca glomerata] gi|334860503|gb|AEH10977.1| D-alanine--D-alanine ligase [Frankia symbiont of Datisca glomerata] Length=385 Score = 396 bits (1017), Expect = 4e-108, Method: Compositional matrix adjust. Identities = 217/382 (57%), Positives = 265/382 (70%), Gaps = 20/382 (5%) Query 9 RRVRVAVVFGGRSNEHAISCVSAGSILRNLDSRRFDVIAVGITPAGSWVLTDANPDALTI 68 RR R+AV++GGRS EHAISCVSAGS+LR LD RR+DV+AVGITP G WVL +PDAL + Sbjct 7 RRTRIAVLYGGRSTEHAISCVSAGSVLRALDRRRYDVVAVGITPDGRWVLGPDDPDALAV 66 Query 69 TNRELPQVKSGSGTELALPADPRRGGQL------VSLPPGAGEV---------LESVDVV 113 + LP V + + + LP DP GG + VS PG + L +VDVV Sbjct 67 RDGVLPAVDA-TARPVVLPGDPTVGGLIALDGVAVSAGPGPADRGTADLGAVGLGAVDVV 125 Query 114 FPVLHGPYGEDGTIQGLLELAGVPYVGAGVLASAVGMDKEFTKKLLAADGLPVGAYAVLR 173 FP+LHGP+GEDGT+QGLLE+A VPYVG+GV ASA MDK++ K LLAA GL +G Y VLR Sbjct 126 FPLLHGPFGEDGTVQGLLEMAAVPYVGSGVFASAAAMDKQYMKILLAAAGLDIGPYTVLR 185 Query 174 PPRSTLHRQECERLGLPVFVKPARGGSSIGVSRVSSWDQLPAAVARARRHDPKVIVEAAI 233 ++ L + ERLGLPVFVKPARGGSSIG+SRV +WD L A+ AR DPKV+VEAA+ Sbjct 186 AGQA-LSGDDRERLGLPVFVKPARGGSSIGISRVDAWDDLATALKAARAVDPKVLVEAAV 244 Query 234 SGRELECGVLEMPD-GTLEASTLGEIRVAGVRGREDSFYDFATKYLDDAAELDVPAKVDD 292 GRE+ECGVL D G EAS E+ VA G FYDF KYL DAA DVPA + Sbjct 245 VGREVECGVLGSLDGGGPEASLPAEVTVASSAGSA-GFYDFEAKYLSDAARFDVPANLPA 303 Query 293 QVAEAIRQLAIRAFAAIDCRGLARVDFFLTDDGP-VINEINTMPGFTTISMYPRMWAASG 351 +V A+RQ+A+RAF A+DC GLARVD F+ DG V+NE+NTMPGFT SM+PRMWAA+G Sbjct 304 EVTAAVRQIAVRAFVALDCAGLARVDVFVRPDGSVVVNEVNTMPGFTPTSMFPRMWAATG 363 Query 352 VDYPTLLATMIETTLARGVGLH 373 +DYP L+ ++ G GLH Sbjct 364 LDYPRLVDRLVALATRHGTGLH 385 >gi|302865845|ref|YP_003834482.1| D-alanine/D-alanine ligase [Micromonospora aurantiaca ATCC 27029] gi|315502390|ref|YP_004081277.1| d-alanine/d-alanine ligase [Micromonospora sp. L5] gi|302568704|gb|ADL44906.1| D-alanine/D-alanine ligase [Micromonospora aurantiaca ATCC 27029] gi|315409009|gb|ADU07126.1| D-alanine/D-alanine ligase [Micromonospora sp. L5] Length=367 Score = 392 bits (1008), Expect = 4e-107, Method: Compositional matrix adjust. Identities = 213/367 (59%), Positives = 257/367 (71%), Gaps = 11/367 (2%) Query 10 RVRVAVVFGGRSNEHAISCVSAGSILRNLDSRRFDVIAVGITPAGSWVLTDANPDALTIT 69 + RVA+VFGGRS EH ISCVSAGS+L LD F+V+ VGIT G WVL +P L I Sbjct 6 KTRVAIVFGGRSPEHGISCVSAGSVLAALDPDEFEVVPVGITRQGQWVLASGDPSGLAIA 65 Query 70 NRELPQVKSGSGTELALPADPRRGGQLVSLPPGAGEV-LESVDVVFPVLHGPYGEDGTIQ 128 +R+LP++ +GSG EL L ADP GG +V L P G V L VDVVFPVLHG YGEDGTIQ Sbjct 66 DRKLPEITAGSGAELVLRADPAVGGLMV-LDPAQGPVALADVDVVFPVLHGAYGEDGTIQ 124 Query 129 GLLELAGVPYVGAGVLASAVGMDKEFTKKLLAADGLPVGAYAVLRPPRSTLHRQECERLG 188 G+LE+A +PYVGA V ASA MDKEFTKKL AA+G+PVG YAVLR S L ++ ERLG Sbjct 125 GMLEMADIPYVGANVFASAAAMDKEFTKKLCAAEGIPVGPYAVLRAGMS-LSDEDKERLG 183 Query 189 LPVFVKPARGGSSIGVSRVSSWDQLPAAVARARRHDPKVIVEAAISGRELECGVLE-MPD 247 LPVFVKP+R GSS G+++V W L AA+ AR D KV+VE A+ GRE+ECGVLE Sbjct 184 LPVFVKPSRAGSSFGITKVDDWADLDAALVTAREIDSKVLVEGAVVGREIECGVLEGEAG 243 Query 248 GTLEASTLGEIRVAGVRGREDSFYDFATKYL--DDAAELDVPAKVDDQVAEAIRQLAIRA 305 G EAS L E+R+ G R +YDF KY+ D+ E DVPA + + VA +R A RA Sbjct 244 GAPEASVLAEVRMIGDR----DWYDFEAKYIFADEVCEYDVPADLPEPVARQVRDYATRA 299 Query 306 FAAIDCRGLARVDFFLTDDGPV-INEINTMPGFTTISMYPRMWAASGVDYPTLLATMIET 364 F A+DC GLARVDFF+T V +NEINTMPGFT SM+PRMW+ASG++YP L+ +I T Sbjct 300 FTALDCSGLARVDFFVTPQMDVYLNEINTMPGFTPTSMFPRMWSASGLEYPKLVNRLIRT 359 Query 365 TLARGVG 371 L R G Sbjct 360 ALHRRAG 366 >gi|238063267|ref|ZP_04607976.1| D-alanine-D-alanine ligase [Micromonospora sp. ATCC 39149] gi|237885078|gb|EEP73906.1| D-alanine-D-alanine ligase [Micromonospora sp. ATCC 39149] Length=365 Score = 391 bits (1004), Expect = 1e-106, Method: Compositional matrix adjust. Identities = 212/366 (58%), Positives = 258/366 (71%), Gaps = 8/366 (2%) Query 10 RVRVAVVFGGRSNEHAISCVSAGSILRNLDSRRFDVIAVGITPAGSWVLTDANPDALTIT 69 + RVA+VFGGRS EH ISCVSAGS+L LD F+V+ VGIT AG WVLT A+P L I+ Sbjct 6 KTRVALVFGGRSPEHGISCVSAGSVLGALDPDEFEVVPVGITRAGKWVLTSADPAQLAIS 65 Query 70 NRELPQVKSGSGTELALPADPRRGGQLVSLPPGAGEVLESVDVVFPVLHGPYGEDGTIQG 129 R LP++ + +G +L L ADP G +V P + VDVVFPVLHG YGEDGTIQG Sbjct 66 ARRLPEITADAGADLVLRADPTGSGLMVLDPAEGPRAIADVDVVFPVLHGAYGEDGTIQG 125 Query 130 LLELAGVPYVGAGVLASAVGMDKEFTKKLLAADGLPVGAYAVLRPPRSTLHRQECERLGL 189 +LE+AG+PYVGA V ASA MDKEFTKKL A +G+PVG YAVLR TL ++ RLGL Sbjct 126 MLEMAGIPYVGANVFASAAAMDKEFTKKLCAVEGIPVGPYAVLR-NGVTLSEEDKRRLGL 184 Query 190 PVFVKPARGGSSIGVSRVSSWDQLPAAVARARRHDPKVIVEAAISGRELECGVL-EMPDG 248 PVFVKP+R GSS G+++V W L AAVA AR DPKV+VEAAI GRE+ECGVL G Sbjct 185 PVFVKPSRAGSSFGITKVDDWVDLEAAVAAAREIDPKVLVEAAIVGREIECGVLEGEAGG 244 Query 249 TLEASTLGEIRVAGVRGREDSFYDFATKYLDDAAELDVPAKVDDQVAEAIRQLAIRAFAA 308 EAS L E+R G + +YDF KYL + E D+PA + + V +++ A+RAFAA Sbjct 245 GAEASVLVEVRAGG----DHDWYDFEAKYLSE-PEYDLPATLPEHVTRQVQEYAVRAFAA 299 Query 309 IDCRGLARVDFFLTDDGPV-INEINTMPGFTTISMYPRMWAASGVDYPTLLATMIETTLA 367 +DC GLARVDFF+T D V +NEINTMPGFT SM+P MWAASG++YP L+ +I T Sbjct 300 LDCAGLARVDFFVTPDLDVYLNEINTMPGFTPTSMFPLMWAASGLEYPKLVNRLIRTAQR 359 Query 368 RGVGLH 373 RGVGLH Sbjct 360 RGVGLH 365 Lambda K H 0.319 0.137 0.402 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 712818967600 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40