BLASTP 2.2.25+
Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
15,229,318 sequences; 5,219,829,388 total letters
Query= Rv2995c
Length=336
Score E
Sequences producing significant alignments: (Bits) Value
gi|289763175|ref|ZP_06522553.1| 3-isopropylmalate dehydrogenase ... 665 0.0
gi|15610132|ref|NP_217511.1| 3-isopropylmalate dehydrogenase [My... 665 0.0
gi|58177068|pdb|1W0D|A Chain A, The High Resolution Structure Of... 663 0.0
gi|289444560|ref|ZP_06434304.1| 3-isopropylmalate dehydrogenase ... 663 0.0
gi|340627984|ref|YP_004746436.1| putative 3-isopropylmalate dehy... 663 0.0
gi|31794171|ref|NP_856664.1| 3-isopropylmalate dehydrogenase [My... 662 0.0
gi|289755113|ref|ZP_06514491.1| LOW QUALITY PROTEIN: 3-isopropyl... 606 2e-171
gi|240168942|ref|ZP_04747601.1| 3-isopropylmalate dehydrogenase ... 573 2e-161
gi|254819119|ref|ZP_05224120.1| 3-isopropylmalate dehydrogenase ... 568 5e-160
gi|108798879|ref|YP_639076.1| 3-isopropylmalate dehydrogenase [M... 566 1e-159
gi|145224812|ref|YP_001135490.1| 3-isopropylmalate dehydrogenase... 565 3e-159
gi|183981729|ref|YP_001850020.1| 3-isopropylmalate dehydrogenase... 565 4e-159
gi|118469173|ref|YP_886721.1| 3-isopropylmalate dehydrogenase [M... 565 4e-159
gi|315445142|ref|YP_004078021.1| 3-isopropylmalate dehydrogenase... 564 7e-159
gi|118617544|ref|YP_905876.1| 3-isopropylmalate dehydrogenase [M... 561 4e-158
gi|296171278|ref|ZP_06852682.1| 3-isopropylmalate dehydrogenase ... 561 4e-158
gi|41409130|ref|NP_961966.1| 3-isopropylmalate dehydrogenase [My... 559 3e-157
gi|118463554|ref|YP_883010.1| 3-isopropylmalate dehydrogenase [M... 558 5e-157
gi|342858179|ref|ZP_08714834.1| 3-isopropylmalate dehydrogenase ... 555 3e-156
gi|120403121|ref|YP_952950.1| 3-isopropylmalate dehydrogenase [M... 544 6e-153
gi|15827899|ref|NP_302162.1| 3-isopropylmalate dehydrogenase [My... 543 2e-152
gi|169630384|ref|YP_001704033.1| 3-isopropylmalate dehydrogenase... 538 7e-151
gi|333991357|ref|YP_004523971.1| 3-isopropylmalate dehydrogenase... 532 2e-149
gi|54026191|ref|YP_120433.1| 3-isopropylmalate dehydrogenase [No... 510 1e-142
gi|262203114|ref|YP_003274322.1| 3-isopropylmalate dehydrogenase... 506 2e-141
gi|326381546|ref|ZP_08203240.1| 3-isopropylmalate dehydrogenase ... 504 8e-141
gi|343926847|ref|ZP_08766340.1| 3-isopropylmalate dehydrogenase ... 495 4e-138
gi|333920855|ref|YP_004494436.1| 3-isopropylmalate dehydrogenase... 482 3e-134
gi|111023451|ref|YP_706423.1| 3-isopropylmalate dehydrogenase [R... 478 4e-133
gi|312140490|ref|YP_004007826.1| 3-isopropylmalate dehydrogenase... 477 1e-132
gi|226365952|ref|YP_002783735.1| 3-isopropylmalate dehydrogenase... 477 1e-132
gi|325675892|ref|ZP_08155576.1| 3-isopropylmalate dehydrogenase ... 476 2e-132
gi|227504456|ref|ZP_03934505.1| 3-isopropylmalate dehydrogenase ... 474 9e-132
gi|296140549|ref|YP_003647792.1| 3-isopropylmalate dehydrogenase... 464 1e-128
gi|213964557|ref|ZP_03392757.1| tartrate dehydrogenase/decarboxy... 462 4e-128
gi|300783618|ref|YP_003763909.1| 3-isopropylmalate dehydrogenase... 462 4e-128
gi|19552506|ref|NP_600508.1| 3-isopropylmalate dehydrogenase [Co... 462 4e-128
gi|296119583|ref|ZP_06838141.1| 3-isopropylmalate dehydrogenase ... 461 6e-128
gi|145295427|ref|YP_001138248.1| 3-isopropylmalate dehydrogenase... 460 1e-127
gi|227832960|ref|YP_002834667.1| 3-isopropylmalate dehydrogenase... 460 1e-127
gi|331695674|ref|YP_004331913.1| 3-isopropylmalate dehydrogenase... 459 2e-127
gi|300858318|ref|YP_003783301.1| 3-isopropylmalate dehydrogenase... 459 3e-127
gi|325003698|ref|ZP_08124810.1| 3-isopropylmalate dehydrogenase ... 459 3e-127
gi|256380007|ref|YP_003103667.1| 3-isopropylmalate dehydrogenase... 458 6e-127
gi|38233699|ref|NP_939466.1| 3-isopropylmalate dehydrogenase [Co... 456 2e-126
gi|302558207|ref|ZP_07310549.1| 3-isopropylmalate dehydrogenase ... 456 3e-126
gi|229819911|ref|YP_002881437.1| 3-isopropylmalate dehydrogenase... 454 8e-126
gi|227501756|ref|ZP_03931805.1| 3-isopropylmalate dehydrogenase ... 452 4e-125
gi|302524969|ref|ZP_07277311.1| tartrate dehydrogenase [Streptom... 451 6e-125
gi|255324582|ref|ZP_05365699.1| 3-isopropylmalate dehydrogenase ... 451 6e-125
>gi|289763175|ref|ZP_06522553.1| 3-isopropylmalate dehydrogenase [Mycobacterium tuberculosis GM
1503]
gi|308379375|ref|ZP_07486067.2| 3-isopropylmalate dehydrogenase leuB [Mycobacterium tuberculosis
SUMu010]
gi|289710681|gb|EFD74697.1| 3-isopropylmalate dehydrogenase [Mycobacterium tuberculosis GM
1503]
gi|308357206|gb|EFP46057.1| 3-isopropylmalate dehydrogenase leuB [Mycobacterium tuberculosis
SUMu010]
gi|339295829|gb|AEJ47940.1| 3-isopropylmalate dehydrogenase [Mycobacterium tuberculosis CCDC5079]
gi|339299442|gb|AEJ51552.1| 3-isopropylmalate dehydrogenase [Mycobacterium tuberculosis CCDC5180]
Length=342
Score = 665 bits (1717), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 336/336 (100%), Positives = 336/336 (100%), Gaps = 0/336 (0%)
Query 1 MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH 60
MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH
Sbjct 7 MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH 66
Query 61 DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDFVVV 120
DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDFVVV
Sbjct 67 DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDFVVV 126
Query 121 REGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVHKTN 180
REGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVHKTN
Sbjct 127 REGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVHKTN 186
Query 181 VLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITDL 240
VLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITDL
Sbjct 187 VLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITDL 246
Query 241 AAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHLGE 300
AAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHLGE
Sbjct 247 AAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHLGE 306
Query 301 HDAAARVDRAVEAHLATRGSERLATSDVGERIAAAL 336
HDAAARVDRAVEAHLATRGSERLATSDVGERIAAAL
Sbjct 307 HDAAARVDRAVEAHLATRGSERLATSDVGERIAAAL 342
>gi|15610132|ref|NP_217511.1| 3-isopropylmalate dehydrogenase [Mycobacterium tuberculosis H37Rv]
gi|15842551|ref|NP_337588.1| 3-isopropylmalate dehydrogenase [Mycobacterium tuberculosis CDC1551]
gi|148662845|ref|YP_001284368.1| 3-isopropylmalate dehydrogenase [Mycobacterium tuberculosis H37Ra]
50 more sequence titles
Length=336
Score = 665 bits (1716), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 336/336 (100%), Positives = 336/336 (100%), Gaps = 0/336 (0%)
Query 1 MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH 60
MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH
Sbjct 1 MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH 60
Query 61 DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDFVVV 120
DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDFVVV
Sbjct 61 DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDFVVV 120
Query 121 REGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVHKTN 180
REGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVHKTN
Sbjct 121 REGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVHKTN 180
Query 181 VLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITDL 240
VLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITDL
Sbjct 181 VLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITDL 240
Query 241 AAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHLGE 300
AAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHLGE
Sbjct 241 AAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHLGE 300
Query 301 HDAAARVDRAVEAHLATRGSERLATSDVGERIAAAL 336
HDAAARVDRAVEAHLATRGSERLATSDVGERIAAAL
Sbjct 301 HDAAARVDRAVEAHLATRGSERLATSDVGERIAAAL 336
>gi|58177068|pdb|1W0D|A Chain A, The High Resolution Structure Of Mycobacterium Tuberculosis
Leub (Rv2995c)
gi|58177069|pdb|1W0D|B Chain B, The High Resolution Structure Of Mycobacterium Tuberculosis
Leub (Rv2995c)
gi|58177070|pdb|1W0D|C Chain C, The High Resolution Structure Of Mycobacterium Tuberculosis
Leub (Rv2995c)
gi|58177071|pdb|1W0D|D Chain D, The High Resolution Structure Of Mycobacterium Tuberculosis
Leub (Rv2995c)
gi|134104337|pdb|2G4O|A Chain A, Anomalous Substructure Of 3-Isopropylmalate Dehydrogenase
gi|134104338|pdb|2G4O|B Chain B, Anomalous Substructure Of 3-Isopropylmalate Dehydrogenase
gi|134104339|pdb|2G4O|C Chain C, Anomalous Substructure Of 3-Isopropylmalate Dehydrogenase
gi|134104340|pdb|2G4O|D Chain D, Anomalous Substructure Of 3-Isopropylmalate Dehydrogenase
Length=337
Score = 663 bits (1711), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 335/335 (100%), Positives = 335/335 (100%), Gaps = 0/335 (0%)
Query 2 KLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNHD 61
KLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNHD
Sbjct 3 KLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNHD 62
Query 62 AILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDFVVVR 121
AILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDFVVVR
Sbjct 63 AILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDFVVVR 122
Query 122 EGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVHKTNV 181
EGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVHKTNV
Sbjct 123 EGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVHKTNV 182
Query 182 LTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITDLA 241
LTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITDLA
Sbjct 183 LTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITDLA 242
Query 242 AAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHLGEH 301
AAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHLGEH
Sbjct 243 AAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHLGEH 302
Query 302 DAAARVDRAVEAHLATRGSERLATSDVGERIAAAL 336
DAAARVDRAVEAHLATRGSERLATSDVGERIAAAL
Sbjct 303 DAAARVDRAVEAHLATRGSERLATSDVGERIAAAL 337
>gi|289444560|ref|ZP_06434304.1| 3-isopropylmalate dehydrogenase leuB [Mycobacterium tuberculosis
T46]
gi|289751672|ref|ZP_06511050.1| 3-isopropylmalate dehydrogenase leuB [Mycobacterium tuberculosis
T92]
gi|289417479|gb|EFD14719.1| 3-isopropylmalate dehydrogenase leuB [Mycobacterium tuberculosis
T46]
gi|289692259|gb|EFD59688.1| 3-isopropylmalate dehydrogenase leuB [Mycobacterium tuberculosis
T92]
Length=336
Score = 663 bits (1711), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 335/336 (99%), Positives = 335/336 (99%), Gaps = 0/336 (0%)
Query 1 MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH 60
MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH
Sbjct 1 MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH 60
Query 61 DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDFVVV 120
DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDFVVV
Sbjct 61 DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDFVVV 120
Query 121 REGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVHKTN 180
REGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVHK N
Sbjct 121 REGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVHKIN 180
Query 181 VLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITDL 240
VLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITDL
Sbjct 181 VLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITDL 240
Query 241 AAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHLGE 300
AAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHLGE
Sbjct 241 AAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHLGE 300
Query 301 HDAAARVDRAVEAHLATRGSERLATSDVGERIAAAL 336
HDAAARVDRAVEAHLATRGSERLATSDVGERIAAAL
Sbjct 301 HDAAARVDRAVEAHLATRGSERLATSDVGERIAAAL 336
>gi|340627984|ref|YP_004746436.1| putative 3-isopropylmalate dehydrogenase LEUB [Mycobacterium
canettii CIPT 140010059]
gi|340006174|emb|CCC45348.1| putative 3-isopropylmalate dehydrogenase LEUB (beta-IPM dehydrogenase)
(IMDH) (3-IPM-DH) [Mycobacterium canettii CIPT 140010059]
Length=336
Score = 663 bits (1710), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 335/336 (99%), Positives = 335/336 (99%), Gaps = 0/336 (0%)
Query 1 MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH 60
MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH
Sbjct 1 MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH 60
Query 61 DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDFVVV 120
DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDFVVV
Sbjct 61 DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDFVVV 120
Query 121 REGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVHKTN 180
REGTEGPY GNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVHKTN
Sbjct 121 REGTEGPYAGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVHKTN 180
Query 181 VLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITDL 240
VLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITDL
Sbjct 181 VLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITDL 240
Query 241 AAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHLGE 300
AAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHLGE
Sbjct 241 AAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHLGE 300
Query 301 HDAAARVDRAVEAHLATRGSERLATSDVGERIAAAL 336
HDAAARVDRAVEAHLATRGSERLATSDVGERIAAAL
Sbjct 301 HDAAARVDRAVEAHLATRGSERLATSDVGERIAAAL 336
>gi|31794171|ref|NP_856664.1| 3-isopropylmalate dehydrogenase [Mycobacterium bovis AF2122/97]
gi|121638876|ref|YP_979100.1| 3-isopropylmalate dehydrogenase [Mycobacterium bovis BCG str.
Pasteur 1173P2]
gi|224991368|ref|YP_002646057.1| 3-isopropylmalate dehydrogenase [Mycobacterium bovis BCG str.
Tokyo 172]
14 more sequence titles
Length=336
Score = 662 bits (1709), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 335/336 (99%), Positives = 335/336 (99%), Gaps = 0/336 (0%)
Query 1 MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH 60
MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH
Sbjct 1 MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH 60
Query 61 DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDFVVV 120
DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDFVVV
Sbjct 61 DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDFVVV 120
Query 121 REGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVHKTN 180
REGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVHKTN
Sbjct 121 REGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVHKTN 180
Query 181 VLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITDL 240
VLT AGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITDL
Sbjct 181 VLTLAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITDL 240
Query 241 AAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHLGE 300
AAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHLGE
Sbjct 241 AAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHLGE 300
Query 301 HDAAARVDRAVEAHLATRGSERLATSDVGERIAAAL 336
HDAAARVDRAVEAHLATRGSERLATSDVGERIAAAL
Sbjct 301 HDAAARVDRAVEAHLATRGSERLATSDVGERIAAAL 336
>gi|289755113|ref|ZP_06514491.1| LOW QUALITY PROTEIN: 3-isopropylmalate dehydrogenase [Mycobacterium
tuberculosis EAS054]
gi|289695700|gb|EFD63129.1| LOW QUALITY PROTEIN: 3-isopropylmalate dehydrogenase [Mycobacterium
tuberculosis EAS054]
Length=338
Score = 606 bits (1562), Expect = 2e-171, Method: Compositional matrix adjust.
Identities = 324/333 (98%), Positives = 325/333 (98%), Gaps = 1/333 (0%)
Query 1 MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH 60
MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH
Sbjct 1 MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH 60
Query 61 DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDFVVV 120
DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDFVVV
Sbjct 61 DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDFVVV 120
Query 121 REGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVHKTN 180
REGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVHKTN
Sbjct 121 REGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVHKTN 180
Query 181 VLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITDL 240
VLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITDL
Sbjct 181 VLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITDL 240
Query 241 AAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHLGE 300
AAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHLGE
Sbjct 241 AAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHLGE 300
Query 301 HDAAARVDRAVEAHLATRGSER-LATSDVGERI 332
HDAAARVDRAVEAHLATRG L + GERI
Sbjct 301 HDAAARVDRAVEAHLATRGQRNGLPPAMSGERI 333
>gi|240168942|ref|ZP_04747601.1| 3-isopropylmalate dehydrogenase [Mycobacterium kansasii ATCC
12478]
Length=336
Score = 573 bits (1476), Expect = 2e-161, Method: Compositional matrix adjust.
Identities = 301/336 (90%), Positives = 316/336 (95%), Gaps = 0/336 (0%)
Query 1 MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH 60
MKLAIIAGDGIGPEV AEAVKVLDAV+PGVQKT YDLGA RFHATGE+LPD+V+AELR H
Sbjct 1 MKLAIIAGDGIGPEVVAEAVKVLDAVLPGVQKTGYDLGASRFHATGELLPDTVLAELREH 60
Query 61 DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDFVVV 120
DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGV SPL+GNP IDF+VV
Sbjct 61 DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVNSPLAGNPDIDFLVV 120
Query 121 REGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVHKTN 180
REGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFG RRVVADAFERARRRRKHLTLVHKTN
Sbjct 121 REGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGARRVVADAFERARRRRKHLTLVHKTN 180
Query 181 VLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITDL 240
VLTFAG LW RTV E+ + YPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITDL
Sbjct 181 VLTFAGSLWWRTVQEIAKKYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITDL 240
Query 241 AAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHLGE 300
AAAVCGGIGLAASGNIDATR NPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLL+H+GE
Sbjct 241 AAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLAHVGE 300
Query 301 HDAAARVDRAVEAHLATRGSERLATSDVGERIAAAL 336
DAA RVDRAVE LATRG++RL T+ +G+RI AAL
Sbjct 301 DDAAGRVDRAVEKFLATRGNQRLTTTVIGDRIVAAL 336
>gi|254819119|ref|ZP_05224120.1| 3-isopropylmalate dehydrogenase [Mycobacterium intracellulare
ATCC 13950]
Length=336
Score = 568 bits (1464), Expect = 5e-160, Method: Compositional matrix adjust.
Identities = 302/336 (90%), Positives = 314/336 (94%), Gaps = 0/336 (0%)
Query 1 MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH 60
MKLA+I GDGIGPEV AEAVKVLDAV+PGV+KTSYDLGARR+HATGE+LPDS V ELR H
Sbjct 1 MKLAVIEGDGIGPEVVAEAVKVLDAVLPGVEKTSYDLGARRYHATGELLPDSAVDELRAH 60
Query 61 DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDFVVV 120
DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRP RLYPGV SPL+GNP IDFVVV
Sbjct 61 DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPGRLYPGVNSPLAGNPDIDFVVV 120
Query 121 REGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVHKTN 180
REGTEGPYTG GGAIRVGTPNEVATEVS NTAFGVRRVVADAFERA+RRRKHLTLVHKTN
Sbjct 121 REGTEGPYTGTGGAIRVGTPNEVATEVSQNTAFGVRRVVADAFERAQRRRKHLTLVHKTN 180
Query 181 VLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITDL 240
VLTFAG LW R V EVG YPDVEVAYQH+DAATI M+TDPGRFDVIVTDNLFGDIITDL
Sbjct 181 VLTFAGRLWSRIVAEVGRDYPDVEVAYQHIDAATIFMVTDPGRFDVIVTDNLFGDIITDL 240
Query 241 AAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHLGE 300
+AAVCGGIGLAASGNIDATR NPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLL+HLGE
Sbjct 241 SAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLAHLGE 300
Query 301 HDAAARVDRAVEAHLATRGSERLATSDVGERIAAAL 336
DAAARVDRAVE HLATRGSERLAT +VGERIAA L
Sbjct 301 DDAAARVDRAVERHLATRGSERLATREVGERIAAGL 336
>gi|108798879|ref|YP_639076.1| 3-isopropylmalate dehydrogenase [Mycobacterium sp. MCS]
gi|119867994|ref|YP_937946.1| 3-isopropylmalate dehydrogenase [Mycobacterium sp. KMS]
gi|126434479|ref|YP_001070170.1| 3-isopropylmalate dehydrogenase [Mycobacterium sp. JLS]
6 more sequence titles
Length=336
Score = 566 bits (1460), Expect = 1e-159, Method: Compositional matrix adjust.
Identities = 279/336 (84%), Positives = 306/336 (92%), Gaps = 0/336 (0%)
Query 1 MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH 60
M LAIIAGDGIGPEV EAVKVLDAV+P V+KT+YDLGARR+HATGE+LPDSV+ EL+ H
Sbjct 1 MNLAIIAGDGIGPEVIGEAVKVLDAVLPEVEKTTYDLGARRYHATGEILPDSVLEELKVH 60
Query 61 DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDFVVV 120
DAILLGAIGDPSVPSGVLERGLLLR+RF LDHHINLRPA+LY GV PL+GNP IDFVVV
Sbjct 61 DAILLGAIGDPSVPSGVLERGLLLRIRFALDHHINLRPAKLYSGVTGPLAGNPEIDFVVV 120
Query 121 REGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVHKTN 180
REGTEGPYTG GGAIRVGTP+EVATEVS+NTAFGVRRVV DAF RA++RRKHLTLVHK N
Sbjct 121 REGTEGPYTGTGGAIRVGTPHEVATEVSLNTAFGVRRVVEDAFRRAQQRRKHLTLVHKNN 180
Query 181 VLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITDL 240
VLTFAG LW RTV EVG YPDVE+AYQHVD+A IH++TDPGRFDVIVTDNLFGDI+TDL
Sbjct 181 VLTFAGALWWRTVQEVGAEYPDVEIAYQHVDSAMIHIVTDPGRFDVIVTDNLFGDIVTDL 240
Query 241 AAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHLGE 300
AAAVCGGIGLAASGNIDATR NPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLL+H+GE
Sbjct 241 AAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLAHVGE 300
Query 301 HDAAARVDRAVEAHLATRGSERLATSDVGERIAAAL 336
DAAARVD+AVEAHL++RG + L T+ VG+RI L
Sbjct 301 TDAAARVDKAVEAHLSSRGDQELGTAAVGDRIVGLL 336
>gi|145224812|ref|YP_001135490.1| 3-isopropylmalate dehydrogenase [Mycobacterium gilvum PYR-GCK]
gi|189046498|sp|A4TE12.1|LEU3_MYCGI RecName: Full=3-isopropylmalate dehydrogenase; AltName: Full=3-IPM-DH;
AltName: Full=Beta-IPM dehydrogenase; Short=IMDH
gi|145217298|gb|ABP46702.1| 3-isopropylmalate dehydrogenase [Mycobacterium gilvum PYR-GCK]
Length=336
Score = 565 bits (1457), Expect = 3e-159, Method: Compositional matrix adjust.
Identities = 279/336 (84%), Positives = 305/336 (91%), Gaps = 0/336 (0%)
Query 1 MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH 60
MKLA+IAGDGIGPEV EA++VLDAVVPGV+KT YDLGAR +H TGEVLPDSV+ EL+ H
Sbjct 1 MKLAVIAGDGIGPEVIGEALRVLDAVVPGVEKTEYDLGARLYHRTGEVLPDSVLDELKGH 60
Query 61 DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDFVVV 120
DAILLGAIGDPS+PSGVLERGLLLR+RFELDHHINLRP RLYPGV SPL+GNP IDFVVV
Sbjct 61 DAILLGAIGDPSMPSGVLERGLLLRIRFELDHHINLRPGRLYPGVQSPLAGNPEIDFVVV 120
Query 121 REGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVHKTN 180
REGTEGPYTGNGGAIRVGTP+E+ATEVSVNTA+GVRRVV DAF+RA++RRKHLTLVHK N
Sbjct 121 REGTEGPYTGNGGAIRVGTPHEIATEVSVNTAYGVRRVVQDAFKRAQQRRKHLTLVHKNN 180
Query 181 VLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITDL 240
VLT AG LW RTV V YP+VEVAYQHVDAATIHM+TDPGRFDVIVTDNLFGDIITDL
Sbjct 181 VLTNAGSLWWRTVQAVAAEYPEVEVAYQHVDAATIHMVTDPGRFDVIVTDNLFGDIITDL 240
Query 241 AAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHLGE 300
AAAVCGGIGLAASGNIDAT NPSMFEPVHGSAPDIAGQGIADPTAAIMSV+LLL+H+ E
Sbjct 241 AAAVCGGIGLAASGNIDATLTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVSLLLAHMAE 300
Query 301 HDAAARVDRAVEAHLATRGSERLATSDVGERIAAAL 336
DAAARVD+AV HLATRG E+L+T+ VG+RI L
Sbjct 301 IDAAARVDKAVAEHLATRGDEKLSTTQVGDRILGKL 336
>gi|183981729|ref|YP_001850020.1| 3-isopropylmalate dehydrogenase LeuB [Mycobacterium marinum M]
gi|226735928|sp|B2HIH1.1|LEU3_MYCMM RecName: Full=3-isopropylmalate dehydrogenase; AltName: Full=3-IPM-DH;
AltName: Full=Beta-IPM dehydrogenase; Short=IMDH
gi|183175055|gb|ACC40165.1| 3-isopropylmalate dehydrogenase LeuB [Mycobacterium marinum M]
Length=339
Score = 565 bits (1455), Expect = 4e-159, Method: Compositional matrix adjust.
Identities = 300/339 (89%), Positives = 316/339 (94%), Gaps = 3/339 (0%)
Query 1 MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH 60
MKLAI+AGDGIGPEV A+AVKVLD V PGV+KT+YDLGARRFHATGE+LPDSV+AELR H
Sbjct 1 MKLAIVAGDGIGPEVVAQAVKVLDVVQPGVEKTNYDLGARRFHATGEILPDSVIAELREH 60
Query 61 DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLS---GNPGIDF 117
DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRP RLYPGV SPL+ GNP IDF
Sbjct 61 DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPGRLYPGVKSPLALEPGNPEIDF 120
Query 118 VVVREGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVH 177
VVVREGTEGPYTGNGGAIRVGT NEVATEVSVNTAFGVRRVV DAFERA RRRKHLTLVH
Sbjct 121 VVVREGTEGPYTGNGGAIRVGTANEVATEVSVNTAFGVRRVVRDAFERAMRRRKHLTLVH 180
Query 178 KTNVLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDII 237
K NVLTFAG LW RTV E+GE YPDVE+AYQHVDAATIHM+TDPGRFDVIVTDNLFGDII
Sbjct 181 KNNVLTFAGSLWWRTVQEIGEEYPDVELAYQHVDAATIHMVTDPGRFDVIVTDNLFGDII 240
Query 238 TDLAAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSH 297
TDLAAAVCGGIGLAASGNIDATR NPSMFEPVHGSAPDIAGQGIADPTAAIMSV+LLL+H
Sbjct 241 TDLAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVSLLLAH 300
Query 298 LGEHDAAARVDRAVEAHLATRGSERLATSDVGERIAAAL 336
LG DAA+RVDRAVE +LATRG+ERLAT+ VGERIAAAL
Sbjct 301 LGLDDAASRVDRAVEGYLATRGNERLATAAVGERIAAAL 339
>gi|118469173|ref|YP_886721.1| 3-isopropylmalate dehydrogenase [Mycobacterium smegmatis str.
MC2 155]
gi|118170460|gb|ABK71356.1| 3-isopropylmalate dehydrogenase [Mycobacterium smegmatis str.
MC2 155]
Length=340
Score = 565 bits (1455), Expect = 4e-159, Method: Compositional matrix adjust.
Identities = 278/336 (83%), Positives = 303/336 (91%), Gaps = 0/336 (0%)
Query 1 MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH 60
+KLA+IAGDGIGPEV AEAV VLDAV+PGV+KT YDLGARR+HATGE+L D + ELR +
Sbjct 5 LKLAVIAGDGIGPEVIAEAVTVLDAVLPGVEKTEYDLGARRYHATGELLSDETIEELRGY 64
Query 61 DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDFVVV 120
DAILLGAIGDPSVPSGVLERG+LL+LRF LDHH+NLRP RLYPGV PL GNP IDFVVV
Sbjct 65 DAILLGAIGDPSVPSGVLERGMLLKLRFALDHHVNLRPGRLYPGVTGPLVGNPPIDFVVV 124
Query 121 REGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVHKTN 180
REGTEGPYTGNGGA+RVGTP+EVATEVSVNTAFGV RVV DAF RA+ RRKHLTLVHKTN
Sbjct 125 REGTEGPYTGNGGALRVGTPHEVATEVSVNTAFGVERVVRDAFARAQDRRKHLTLVHKTN 184
Query 181 VLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITDL 240
VL FAG LW RTVD V + YPDVEVAYQH+DAATIHM+TDPGRFDVIVTDNLFGDIITDL
Sbjct 185 VLAFAGSLWSRTVDRVAQEYPDVEVAYQHIDAATIHMVTDPGRFDVIVTDNLFGDIITDL 244
Query 241 AAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHLGE 300
AAAVCGGIGLAASGNIDATR NPSMFEPVHGSAPDIAGQGIADPTAA+MSV LLLSH+G+
Sbjct 245 AAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAVMSVGLLLSHVGQ 304
Query 301 HDAAARVDRAVEAHLATRGSERLATSDVGERIAAAL 336
+AAARVD+AV HLATRG E+L+TS VGERI + L
Sbjct 305 TEAAARVDKAVSEHLATRGDEKLSTSAVGERIRSLL 340
>gi|315445142|ref|YP_004078021.1| 3-isopropylmalate dehydrogenase [Mycobacterium sp. Spyr1]
gi|315263445|gb|ADU00187.1| 3-isopropylmalate dehydrogenase [Mycobacterium sp. Spyr1]
Length=336
Score = 564 bits (1454), Expect = 7e-159, Method: Compositional matrix adjust.
Identities = 278/336 (83%), Positives = 304/336 (91%), Gaps = 0/336 (0%)
Query 1 MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH 60
MKLA+IAGDGIGPEV EA++VLDAVVPGV+KT YDLGAR +H TGEVLPDSV+ EL+ H
Sbjct 1 MKLAVIAGDGIGPEVIGEALRVLDAVVPGVEKTEYDLGARLYHRTGEVLPDSVLDELKGH 60
Query 61 DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDFVVV 120
DAILLGAIGDPS+PSGVLERGLLLR+RFELDHHINLRP RLYPGV SPL+GNP IDFVVV
Sbjct 61 DAILLGAIGDPSMPSGVLERGLLLRIRFELDHHINLRPGRLYPGVQSPLAGNPEIDFVVV 120
Query 121 REGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVHKTN 180
REGTEGPYTGNGGAIRVGTP+E+ATEVSVNTA+GVRRVV DAF+RA++RRKHLTLVHK N
Sbjct 121 REGTEGPYTGNGGAIRVGTPHEIATEVSVNTAYGVRRVVQDAFKRAQQRRKHLTLVHKNN 180
Query 181 VLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITDL 240
VLT AG LW RTV V YP+VEVAYQHVDAATIHM+TDPGRFDVIVTDNLFGDIITDL
Sbjct 181 VLTNAGSLWWRTVQAVAAEYPEVEVAYQHVDAATIHMVTDPGRFDVIVTDNLFGDIITDL 240
Query 241 AAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHLGE 300
AAAVCGGIGLAASGNIDAT NPSMFEPVHGSAPDIAGQGIADPTAAIMSV+LLL+H+ E
Sbjct 241 AAAVCGGIGLAASGNIDATLTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVSLLLAHMAE 300
Query 301 HDAAARVDRAVEAHLATRGSERLATSDVGERIAAAL 336
DAA RVD+AV HLATRG E+L+T+ VG+RI L
Sbjct 301 IDAAVRVDKAVAEHLATRGDEKLSTTQVGDRILGKL 336
>gi|118617544|ref|YP_905876.1| 3-isopropylmalate dehydrogenase [Mycobacterium ulcerans Agy99]
gi|166989782|sp|A0PPY6.1|LEU3_MYCUA RecName: Full=3-isopropylmalate dehydrogenase; AltName: Full=3-IPM-DH;
AltName: Full=Beta-IPM dehydrogenase; Short=IMDH
gi|118569654|gb|ABL04405.1| 3-isopropylmalate dehydrogenase LeuB [Mycobacterium ulcerans
Agy99]
Length=339
Score = 561 bits (1447), Expect = 4e-158, Method: Compositional matrix adjust.
Identities = 297/339 (88%), Positives = 315/339 (93%), Gaps = 3/339 (0%)
Query 1 MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH 60
MKLAI+AGDGIGPEV A+AVK+LD V PGV+KT+YDLGARRFHATGE+LPDSV+AELR H
Sbjct 1 MKLAIVAGDGIGPEVVAQAVKILDVVQPGVEKTNYDLGARRFHATGEILPDSVIAELREH 60
Query 61 DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLS---GNPGIDF 117
DAILLGAIGDPSVPSGVLERGLLLRLRFELD+HINLRP RLYPGV SPL+ GNP IDF
Sbjct 61 DAILLGAIGDPSVPSGVLERGLLLRLRFELDYHINLRPGRLYPGVKSPLALEPGNPEIDF 120
Query 118 VVVREGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVH 177
VVVREGTEGPYTGNGGAIRVGT NEVATEVSVNTAFGVRRVV DAFERA RRRKHLTLVH
Sbjct 121 VVVREGTEGPYTGNGGAIRVGTANEVATEVSVNTAFGVRRVVRDAFERAMRRRKHLTLVH 180
Query 178 KTNVLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDII 237
K NVLTFAG LW RTV E+GE YPDVE+AYQHVDAATIHM+TDPGRFDVIVTDNLFGDII
Sbjct 181 KNNVLTFAGSLWWRTVQEIGEEYPDVELAYQHVDAATIHMVTDPGRFDVIVTDNLFGDII 240
Query 238 TDLAAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSH 297
TDLAAAVCGGIGLAASGNIDATR NPSMFEPVHGSAPDIAGQGIADPTAAIMSV+LLL+H
Sbjct 241 TDLAAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVSLLLAH 300
Query 298 LGEHDAAARVDRAVEAHLATRGSERLATSDVGERIAAAL 336
LG D A+RVDRAVE +LATRG+ERLAT+ VGERIAAAL
Sbjct 301 LGLDDTASRVDRAVEGYLATRGNERLATAAVGERIAAAL 339
>gi|296171278|ref|ZP_06852682.1| 3-isopropylmalate dehydrogenase [Mycobacterium parascrofulaceum
ATCC BAA-614]
gi|295894246|gb|EFG74003.1| 3-isopropylmalate dehydrogenase [Mycobacterium parascrofulaceum
ATCC BAA-614]
Length=336
Score = 561 bits (1447), Expect = 4e-158, Method: Compositional matrix adjust.
Identities = 295/336 (88%), Positives = 317/336 (95%), Gaps = 0/336 (0%)
Query 1 MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH 60
MKLA+I GDGIGPEVTAEA+KVLDAV+PGV+KT YDLGARRFHA+GE+LP+SV+ ELR H
Sbjct 1 MKLAVIGGDGIGPEVTAEALKVLDAVLPGVEKTDYDLGARRFHASGELLPESVLGELRQH 60
Query 61 DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDFVVV 120
DAILLGAIGDPSVPSGVLERGLLLRLRFELDHH+NLRP RLYPGV+SPL+G+P IDFVVV
Sbjct 61 DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHVNLRPGRLYPGVSSPLAGDPHIDFVVV 120
Query 121 REGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVHKTN 180
REGTEGPYTG GGAIR GTP+EVATEVS+NTAFGVRRVVADAFERA+RRRKHLTLVHKTN
Sbjct 121 REGTEGPYTGTGGAIRTGTPHEVATEVSLNTAFGVRRVVADAFERAQRRRKHLTLVHKTN 180
Query 181 VLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITDL 240
VLTFAG LW R V EVG YPDVEVAYQH+DAATI M+TDPGRFDVIVTDNLFGDIITDL
Sbjct 181 VLTFAGKLWSRIVAEVGRDYPDVEVAYQHIDAATIFMVTDPGRFDVIVTDNLFGDIITDL 240
Query 241 AAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHLGE 300
AAAVCGGIGLAASGNIDATR NPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLL+HLGE
Sbjct 241 AAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLAHLGE 300
Query 301 HDAAARVDRAVEAHLATRGSERLATSDVGERIAAAL 336
DAA+RVDRAVEA+LATRGSER AT++VGERIAA L
Sbjct 301 DDAASRVDRAVEAYLATRGSERPATTEVGERIAAGL 336
>gi|41409130|ref|NP_961966.1| 3-isopropylmalate dehydrogenase [Mycobacterium avium subsp. paratuberculosis
K-10]
gi|81571105|sp|Q73VI1.1|LEU3_MYCPA RecName: Full=3-isopropylmalate dehydrogenase; AltName: Full=3-IPM-DH;
AltName: Full=Beta-IPM dehydrogenase; Short=IMDH
gi|41397950|gb|AAS05580.1| LeuB [Mycobacterium avium subsp. paratuberculosis K-10]
gi|336459110|gb|EGO38058.1| isocitrate/isopropylmalate dehydrogenase [Mycobacterium avium
subsp. paratuberculosis S397]
Length=336
Score = 559 bits (1440), Expect = 3e-157, Method: Compositional matrix adjust.
Identities = 296/336 (89%), Positives = 312/336 (93%), Gaps = 0/336 (0%)
Query 1 MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH 60
MKLA+I GDGIGPEVTAEA+KVLDAV+PGV KT YDLGARR+HATGE+LPDSV+ ELR H
Sbjct 1 MKLAVIGGDGIGPEVTAEALKVLDAVLPGVDKTEYDLGARRYHATGELLPDSVIDELRAH 60
Query 61 DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDFVVV 120
DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRP RLYPGV+SPL+GNP IDFVVV
Sbjct 61 DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPGRLYPGVSSPLAGNPDIDFVVV 120
Query 121 REGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVHKTN 180
REGTEGPYTG GGAIRVGTPNEVATEVS NTAFGVRRVV DAFERARRRRKHLTLVHKTN
Sbjct 121 REGTEGPYTGTGGAIRVGTPNEVATEVSQNTAFGVRRVVVDAFERARRRRKHLTLVHKTN 180
Query 181 VLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITDL 240
VLTFAG LW R V EVG YPDVEVAYQH+DAATI M+TDPGRFDVIVTDNLFGDIITDL
Sbjct 181 VLTFAGKLWSRIVAEVGRDYPDVEVAYQHIDAATIFMVTDPGRFDVIVTDNLFGDIITDL 240
Query 241 AAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHLGE 300
+AAVCGGIGLAASGNID TR NPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLL+HLGE
Sbjct 241 SAAVCGGIGLAASGNIDGTRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLAHLGE 300
Query 301 HDAAARVDRAVEAHLATRGSERLATSDVGERIAAAL 336
AA RVDRAVE +LATRG+ER AT++VGERIAAAL
Sbjct 301 DAAATRVDRAVERYLATRGNERPATTEVGERIAAAL 336
>gi|118463554|ref|YP_883010.1| 3-isopropylmalate dehydrogenase [Mycobacterium avium 104]
gi|254776267|ref|ZP_05217783.1| 3-isopropylmalate dehydrogenase [Mycobacterium avium subsp. avium
ATCC 25291]
gi|166989777|sp|A0QJC2.1|LEU3_MYCA1 RecName: Full=3-isopropylmalate dehydrogenase; AltName: Full=3-IPM-DH;
AltName: Full=Beta-IPM dehydrogenase; Short=IMDH
gi|118164841|gb|ABK65738.1| 3-isopropylmalate dehydrogenase [Mycobacterium avium 104]
Length=336
Score = 558 bits (1438), Expect = 5e-157, Method: Compositional matrix adjust.
Identities = 295/336 (88%), Positives = 312/336 (93%), Gaps = 0/336 (0%)
Query 1 MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH 60
MKLA+I GDGIGPEVTAEA+KVLDAV+PGV KT YDLGARR+HATGE+LPDSV+ ELR H
Sbjct 1 MKLAVIGGDGIGPEVTAEALKVLDAVLPGVDKTEYDLGARRYHATGELLPDSVIDELRAH 60
Query 61 DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDFVVV 120
DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRP RLYPGV+SPL+GNP IDFVVV
Sbjct 61 DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPGRLYPGVSSPLAGNPDIDFVVV 120
Query 121 REGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVHKTN 180
REGTEGPYTG GGAIRVGTPNEVATEVS NTAFGVRRVV DAFERARRRRKHLTLVHKTN
Sbjct 121 REGTEGPYTGTGGAIRVGTPNEVATEVSQNTAFGVRRVVVDAFERARRRRKHLTLVHKTN 180
Query 181 VLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITDL 240
VLTFAG LW R V EVG YPDVEVAYQH+DAATI M+TDPGRFDVIVTDNLFGDIITDL
Sbjct 181 VLTFAGKLWSRIVAEVGRDYPDVEVAYQHIDAATIFMVTDPGRFDVIVTDNLFGDIITDL 240
Query 241 AAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHLGE 300
+AAVCGGIGLAASGNID TR NPSMFEPVHGSAPDIAGQG+ADPTAAIMSVALLL+HLGE
Sbjct 241 SAAVCGGIGLAASGNIDGTRTNPSMFEPVHGSAPDIAGQGVADPTAAIMSVALLLAHLGE 300
Query 301 HDAAARVDRAVEAHLATRGSERLATSDVGERIAAAL 336
AA RVDRAVE +LATRG+ER AT++VGERIAAAL
Sbjct 301 DAAATRVDRAVERYLATRGNERPATTEVGERIAAAL 336
>gi|342858179|ref|ZP_08714834.1| 3-isopropylmalate dehydrogenase [Mycobacterium colombiense CECT
3035]
gi|342133883|gb|EGT87063.1| 3-isopropylmalate dehydrogenase [Mycobacterium colombiense CECT
3035]
Length=336
Score = 555 bits (1431), Expect = 3e-156, Method: Compositional matrix adjust.
Identities = 296/336 (89%), Positives = 308/336 (92%), Gaps = 0/336 (0%)
Query 1 MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH 60
MKLAII GDGIGPEV AEAVKVLD V+PGV KT YDLGARR+HATGE+LPDSVV ELR H
Sbjct 1 MKLAIIEGDGIGPEVVAEAVKVLDTVLPGVDKTRYDLGARRYHATGELLPDSVVDELRAH 60
Query 61 DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDFVVV 120
DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRP RLYPGV SPL+GNP IDFVVV
Sbjct 61 DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPGRLYPGVNSPLAGNPDIDFVVV 120
Query 121 REGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVHKTN 180
REGTEGPYTG GGAIRVGTPNEVATEVS NTAFGVRRVV DAFERA+RRRKHLTLVHKTN
Sbjct 121 REGTEGPYTGTGGAIRVGTPNEVATEVSQNTAFGVRRVVVDAFERAQRRRKHLTLVHKTN 180
Query 181 VLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITDL 240
VLTFAG LW R V EVG YPDVEVAYQH+DAATI M+TDPGRFDVIVTDNLFGDIITDL
Sbjct 181 VLTFAGRLWSRIVAEVGRDYPDVEVAYQHIDAATIFMVTDPGRFDVIVTDNLFGDIITDL 240
Query 241 AAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHLGE 300
+AAVCGGIGLAASGNID TR NPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLL+HLGE
Sbjct 241 SAAVCGGIGLAASGNIDGTRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLAHLGE 300
Query 301 HDAAARVDRAVEAHLATRGSERLATSDVGERIAAAL 336
DAA RVDRAVE +LATRG ER AT++VGERIAA L
Sbjct 301 DDAATRVDRAVEQYLATRGDERRATTEVGERIAAGL 336
>gi|120403121|ref|YP_952950.1| 3-isopropylmalate dehydrogenase [Mycobacterium vanbaalenii PYR-1]
gi|166989783|sp|A1T6Z4.1|LEU3_MYCVP RecName: Full=3-isopropylmalate dehydrogenase; AltName: Full=3-IPM-DH;
AltName: Full=Beta-IPM dehydrogenase; Short=IMDH
gi|119955939|gb|ABM12944.1| 3-isopropylmalate dehydrogenase [Mycobacterium vanbaalenii PYR-1]
Length=336
Score = 544 bits (1402), Expect = 6e-153, Method: Compositional matrix adjust.
Identities = 279/336 (84%), Positives = 305/336 (91%), Gaps = 0/336 (0%)
Query 1 MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH 60
M+LA+IAGDGIGPEV EA+KVLDAV+PGV+KT YDLGAR++H TGEVLPDSV+ EL+ H
Sbjct 1 MRLAVIAGDGIGPEVITEALKVLDAVLPGVEKTEYDLGARQYHKTGEVLPDSVLEELKGH 60
Query 61 DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDFVVV 120
DAILLGAIGDPSVPSG+LERGLLLR+RFELDHHINLRPARLYPGV SPL+GNP IDFVVV
Sbjct 61 DAILLGAIGDPSVPSGLLERGLLLRIRFELDHHINLRPARLYPGVQSPLAGNPEIDFVVV 120
Query 121 REGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVHKTN 180
REGTEGPYTGNGGAIRVGTP+E+ATEVSVNTAFGVRR V DAF RA++RRKHLTLVHK N
Sbjct 121 REGTEGPYTGNGGAIRVGTPHEIATEVSVNTAFGVRRAVQDAFGRAQQRRKHLTLVHKNN 180
Query 181 VLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITDL 240
VLT AG LW RTV V YPDVEVAYQHVDAATIHM+TDPGRFDVIVTDNLFGDIITDL
Sbjct 181 VLTNAGSLWWRTVQTVAAEYPDVEVAYQHVDAATIHMVTDPGRFDVIVTDNLFGDIITDL 240
Query 241 AAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHLGE 300
AAAVCGGIGLAASGNIDAT +PSMFEPVHGSAPDIAGQGIADPTAA+MSV+LLL+H+ E
Sbjct 241 AAAVCGGIGLAASGNIDATLTHPSMFEPVHGSAPDIAGQGIADPTAAVMSVSLLLAHMAE 300
Query 301 HDAAARVDRAVEAHLATRGSERLATSDVGERIAAAL 336
DAAARVD+AV HLATRG E+L+T+ VGERI L
Sbjct 301 VDAAARVDKAVAEHLATRGDEKLSTAAVGERILGKL 336
>gi|15827899|ref|NP_302162.1| 3-isopropylmalate dehydrogenase [Mycobacterium leprae TN]
gi|221230376|ref|YP_002503792.1| 3-isopropylmalate dehydrogenase [Mycobacterium leprae Br4923]
gi|6016499|sp|O33117.1|LEU3_MYCLE RecName: Full=3-isopropylmalate dehydrogenase; AltName: Full=3-IPM-DH;
AltName: Full=Beta-IPM dehydrogenase; Short=IMDH
gi|254808555|sp|B8ZS15.1|LEU3_MYCLB RecName: Full=3-isopropylmalate dehydrogenase; AltName: Full=3-IPM-DH;
AltName: Full=Beta-IPM dehydrogenase; Short=IMDH
gi|2414552|emb|CAB16441.1| 3-isopropylmalate dehydrogenase [Mycobacterium leprae]
gi|13093452|emb|CAC30644.1| 3-isopropylmalate dehydrogenase [Mycobacterium leprae]
gi|219933483|emb|CAR71786.1| 3-isopropylmalate dehydrogenase [Mycobacterium leprae Br4923]
Length=336
Score = 543 bits (1399), Expect = 2e-152, Method: Compositional matrix adjust.
Identities = 282/336 (84%), Positives = 309/336 (92%), Gaps = 0/336 (0%)
Query 1 MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH 60
MKLAII GDGIGPEV A+AVK+LD V+PGVQKT+YDLGARR+H TGE+LP+SV+AELR H
Sbjct 1 MKLAIIGGDGIGPEVVAQAVKILDVVLPGVQKTTYDLGARRYHTTGELLPESVLAELREH 60
Query 61 DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDFVVV 120
DAILLGA+GDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGV S L+G P IDFVVV
Sbjct 61 DAILLGAVGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVNSLLAGKPDIDFVVV 120
Query 121 REGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVHKTN 180
REGTEGPYTG GGAIRVGTPNEVATEVSVNTAFGVRRVV DAFERAR+RRKHLTLVHK N
Sbjct 121 REGTEGPYTGTGGAIRVGTPNEVATEVSVNTAFGVRRVVQDAFERARQRRKHLTLVHKNN 180
Query 181 VLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITDL 240
VLT+AG LW R V EVGE YPDVEV YQH+DAATI+++T+P RFDVIVTDNLFGDIITDL
Sbjct 181 VLTYAGTLWCRIVQEVGEKYPDVEVVYQHIDAATIYLVTEPSRFDVIVTDNLFGDIITDL 240
Query 241 AAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHLGE 300
AAAVCGGI LAASGNIDATR NPSMFEPVHGSAPDIAGQGIADPTAAIMS+ALLL+HLGE
Sbjct 241 AAAVCGGIALAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSLALLLAHLGE 300
Query 301 HDAAARVDRAVEAHLATRGSERLATSDVGERIAAAL 336
+ AAR+D+AV ++LATRG+ R +T +VGERIAAAL
Sbjct 301 DEPAARLDQAVASYLATRGNGRFSTGEVGERIAAAL 336
>gi|169630384|ref|YP_001704033.1| 3-isopropylmalate dehydrogenase [Mycobacterium abscessus ATCC
19977]
gi|169242351|emb|CAM63379.1| 3-isopropylmalate dehydrogenase (Leu3) [Mycobacterium abscessus]
Length=337
Score = 538 bits (1385), Expect = 7e-151, Method: Compositional matrix adjust.
Identities = 268/335 (80%), Positives = 295/335 (89%), Gaps = 0/335 (0%)
Query 2 KLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNHD 61
KLAIIAGDGIGPEV EAVKVLDAV+PGV KT YDLGARR+ ATGE++PDSV+ ELR HD
Sbjct 3 KLAIIAGDGIGPEVIGEAVKVLDAVLPGVDKTEYDLGARRYLATGELMPDSVLDELRGHD 62
Query 62 AILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDFVVVR 121
AILLGAIGDP+VPSGVLERGLLL RF LDHHINLRPA+LYPGV PL+GNP ID VVVR
Sbjct 63 AILLGAIGDPAVPSGVLERGLLLNTRFALDHHINLRPAKLYPGVTGPLAGNPAIDLVVVR 122
Query 122 EGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVHKTNV 181
EGTEGPYTGNGGAIRV TP+EVATEVS+NT FGV RVV +AFERA R K+LTLVHK NV
Sbjct 123 EGTEGPYTGNGGAIRVDTPHEVATEVSLNTRFGVERVVRNAFERAEARSKNLTLVHKNNV 182
Query 182 LTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITDLA 241
L +AG LW RTV+EV YPDV+V+YQH+DAATIHM+TDPGRFDVIVTDNLFGDIITDL
Sbjct 183 LKYAGTLWTRTVNEVAAEYPDVQVSYQHIDAATIHMVTDPGRFDVIVTDNLFGDIITDLT 242
Query 242 AAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHLGEH 301
AAV GGIGLAASGNID + NPSMFEPVHGSAPDIAGQGIADPTAAI+SV+LLL HLGE
Sbjct 243 AAVTGGIGLAASGNIDGSGKNPSMFEPVHGSAPDIAGQGIADPTAAIVSVSLLLDHLGET 302
Query 302 DAAARVDRAVEAHLATRGSERLATSDVGERIAAAL 336
+AAARV+RAVE HLATRG E+L+TS G+RIA+ L
Sbjct 303 EAAARVERAVEQHLATRGEEKLSTSATGDRIASFL 337
>gi|333991357|ref|YP_004523971.1| 3-isopropylmalate dehydrogenase LeuB [Mycobacterium sp. JDM601]
gi|333487325|gb|AEF36717.1| 3-isopropylmalate dehydrogenase LeuB [Mycobacterium sp. JDM601]
Length=338
Score = 532 bits (1371), Expect = 2e-149, Method: Compositional matrix adjust.
Identities = 263/336 (79%), Positives = 294/336 (88%), Gaps = 0/336 (0%)
Query 1 MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH 60
+KLA+I GDGIGPEV AEAVKVLDAV+PG +KT+YDLGA+R+HATGEVLPDSV+ EL H
Sbjct 3 VKLAVIPGDGIGPEVIAEAVKVLDAVLPGTEKTTYDLGAKRYHATGEVLPDSVLEELGAH 62
Query 61 DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDFVVV 120
D ILLGAIGDPSVPSGVLERGLLL+ RF LDHH+NLRPARLYPGV+ PL GNP ID VVV
Sbjct 63 DVILLGAIGDPSVPSGVLERGLLLKARFALDHHVNLRPARLYPGVSGPLVGNPEIDLVVV 122
Query 121 REGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVHKTN 180
REGTEGPY G GG +R GT +E+A+EVSVNTA+GVRRVV DAF RA+RRRKHLTL+HKTN
Sbjct 123 REGTEGPYAGTGGFLRRGTEHEIASEVSVNTAYGVRRVVHDAFGRAQRRRKHLTLLHKTN 182
Query 181 VLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITDL 240
VL FAG LW RTV E+ YPDVE+AY H DAATI+++TDPGRFDVIVTDNLFGDI+TDL
Sbjct 183 VLNFAGDLWWRTVQEIAAEYPDVEIAYCHTDAATIYLVTDPGRFDVIVTDNLFGDIVTDL 242
Query 241 AAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHLGE 300
AAAVCGGIGLAASGNIDATR NPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLL+H+GE
Sbjct 243 AAAVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLAHVGE 302
Query 301 HDAAARVDRAVEAHLATRGSERLATSDVGERIAAAL 336
AA RVD+AV HLATRG +L+T+ G+RI L
Sbjct 303 DTAAERVDQAVAEHLATRGEAKLSTAATGDRILGLL 338
>gi|54026191|ref|YP_120433.1| 3-isopropylmalate dehydrogenase [Nocardia farcinica IFM 10152]
gi|81602530|sp|Q5YRX2.1|LEU3_NOCFA RecName: Full=3-isopropylmalate dehydrogenase; AltName: Full=3-IPM-DH;
AltName: Full=Beta-IPM dehydrogenase; Short=IMDH
gi|54017699|dbj|BAD59069.1| putative isopropylmalate dehydrogenase [Nocardia farcinica IFM
10152]
Length=335
Score = 510 bits (1313), Expect = 1e-142, Method: Compositional matrix adjust.
Identities = 264/336 (79%), Positives = 295/336 (88%), Gaps = 1/336 (0%)
Query 1 MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH 60
MKLA+I GDGIGPEV AEA+KVLD VVPGV+KT YDLGA+R+HATGE+LPDSV+ ELR H
Sbjct 1 MKLAVIPGDGIGPEVIAEALKVLDVVVPGVEKTEYDLGAKRYHATGEILPDSVLPELREH 60
Query 61 DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDFVVV 120
DAILLGAIGDPSVPSGVLERGLLLR RFELDHH+NLRP+RL+ GV SPL+G P IDFVVV
Sbjct 61 DAILLGAIGDPSVPSGVLERGLLLRTRFELDHHVNLRPSRLFTGVRSPLAGAPDIDFVVV 120
Query 121 REGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVHKTN 180
REGTEGPYTG GGAIRV TP+EVATEVS NT FG+ RVV AF +A+ RRKHLTLVHKTN
Sbjct 121 REGTEGPYTGTGGAIRVRTPHEVATEVSTNTRFGIERVVRYAFAKAQARRKHLTLVHKTN 180
Query 181 VLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITDL 240
VLTFAG LW RTVDEVG +P+V VAYQH+DAATIHM+TDPGRFDVIVTDNLFGDIITDL
Sbjct 181 VLTFAGSLWQRTVDEVGAEFPEVTVAYQHIDAATIHMVTDPGRFDVIVTDNLFGDIITDL 240
Query 241 AAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHLGE 300
AAAV GGIGLAASGNIDA+ NPSMFEPVHGSAPDIAGQ ADPTAAI+SV+LLL+HLG+
Sbjct 241 AAAVSGGIGLAASGNIDASGTNPSMFEPVHGSAPDIAGQSKADPTAAILSVSLLLNHLGD 300
Query 301 HDAAARVDRAVEAHLATRGSERLATSDVGERIAAAL 336
+AAAR+D AV LA R S +T ++G+RIAAA+
Sbjct 301 TEAAARIDAAVAKDLAAR-SGTASTVEIGDRIAAAV 335
>gi|262203114|ref|YP_003274322.1| 3-isopropylmalate dehydrogenase [Gordonia bronchialis DSM 43247]
gi|262086461|gb|ACY22429.1| 3-isopropylmalate dehydrogenase [Gordonia bronchialis DSM 43247]
Length=337
Score = 506 bits (1304), Expect = 2e-141, Method: Compositional matrix adjust.
Identities = 254/332 (77%), Positives = 284/332 (86%), Gaps = 0/332 (0%)
Query 1 MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH 60
MKLA+IAGDGIGPEV EA++VL VVP V T +DLGARR+H GE+L D+ + LR H
Sbjct 1 MKLAVIAGDGIGPEVIGEALEVLKTVVPEVDTTEFDLGARRYHRNGELLTDADLDSLREH 60
Query 61 DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDFVVV 120
DAILLGAIGDPSVPSGVLERGLLL +RF LDHH+NLRP+R PGV +PL+G+P IDFVVV
Sbjct 61 DAILLGAIGDPSVPSGVLERGLLLTMRFALDHHVNLRPSRRLPGVPTPLAGDPDIDFVVV 120
Query 121 REGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVHKTN 180
REGTEGPYTGNGGAIRVGTP EVATEVSVNT FGV RVV +AFERA +RRKHLTLVHKTN
Sbjct 121 REGTEGPYTGNGGAIRVGTPQEVATEVSVNTRFGVERVVRNAFERAAKRRKHLTLVHKTN 180
Query 181 VLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITDL 240
VLTFAG LW R V+E+G +PDV AY HVDAATI+++TDPGRFDVIVTDNLFGDIITD+
Sbjct 181 VLTFAGSLWARAVEEIGTEFPDVTTAYCHVDAATIYLVTDPGRFDVIVTDNLFGDIITDI 240
Query 241 AAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHLGE 300
AAAV GGIGLAASGNIDAT NPSMFEPVHGSAPDIAGQG ADPTAAI+SVALLL HLGE
Sbjct 241 AAAVSGGIGLAASGNIDATGTNPSMFEPVHGSAPDIAGQGKADPTAAILSVALLLDHLGE 300
Query 301 HDAAARVDRAVEAHLATRGSERLATSDVGERI 332
DAA RV++AV LA RG L+T++VG+RI
Sbjct 301 SDAARRVEQAVADDLAERGGSTLSTAEVGKRI 332
>gi|326381546|ref|ZP_08203240.1| 3-isopropylmalate dehydrogenase [Gordonia neofelifaecis NRRL
B-59395]
gi|326199793|gb|EGD56973.1| 3-isopropylmalate dehydrogenase [Gordonia neofelifaecis NRRL
B-59395]
Length=336
Score = 504 bits (1298), Expect = 8e-141, Method: Compositional matrix adjust.
Identities = 250/336 (75%), Positives = 287/336 (86%), Gaps = 0/336 (0%)
Query 1 MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH 60
MKLA+I GDGIGPEV +A++VL + P V+ T YD GARR+HATGE+L D +A +R H
Sbjct 1 MKLAVIPGDGIGPEVVDQALRVLRKLHPEVETTEYDFGARRYHATGELLTDEDIASIREH 60
Query 61 DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDFVVV 120
DAILLGAIGDPSVPSG LERG LL++RF LDHH+NLRP+ LY GVASPL+G+P IDF+VV
Sbjct 61 DAILLGAIGDPSVPSGTLERGFLLKMRFILDHHVNLRPSVLYDGVASPLAGDPKIDFLVV 120
Query 121 REGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVHKTN 180
REGTEGPYTGNGGAIRVGTP+EVATEVSVNT FG+ RV+ DAF RA+ RRK LTLVHK N
Sbjct 121 REGTEGPYTGNGGAIRVGTPHEVATEVSVNTRFGIERVIRDAFARAQARRKKLTLVHKNN 180
Query 181 VLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITDL 240
VL+FAGG+W R V+E+G+ +PDV Y HVDAATI M+TDPGRFDVIVTDNLFGDIITDL
Sbjct 181 VLSFAGGMWTRAVEEIGKEFPDVATDYLHVDAATIFMVTDPGRFDVIVTDNLFGDIITDL 240
Query 241 AAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHLGE 300
AAAV GGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQ IADPTAAI+SVALLL HLG+
Sbjct 241 AAAVSGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQNIADPTAAILSVALLLRHLGD 300
Query 301 HDAAARVDRAVEAHLATRGSERLATSDVGERIAAAL 336
AARV++AV +ATRG R +TS+VG+RI AA+
Sbjct 301 EAGAARVEKAVAGDVATRGENRGSTSEVGDRILAAV 336
>gi|343926847|ref|ZP_08766340.1| 3-isopropylmalate dehydrogenase [Gordonia alkanivorans NBRC 16433]
gi|343763207|dbj|GAA13266.1| 3-isopropylmalate dehydrogenase [Gordonia alkanivorans NBRC 16433]
Length=336
Score = 495 bits (1275), Expect = 4e-138, Method: Compositional matrix adjust.
Identities = 251/332 (76%), Positives = 283/332 (86%), Gaps = 1/332 (0%)
Query 1 MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH 60
MKLAIIAGDGIGPEV EA+ VL+ VVP V T +DLGARR+H GE+L + + LR+H
Sbjct 1 MKLAIIAGDGIGPEVIGEALGVLETVVPSVSTTEFDLGARRYHRNGELLTEDDLESLRSH 60
Query 61 DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDFVVV 120
DAILLGAIGDPSVP G+LERGLLL +RF LDHH+NLRP+R YPGV SPL+G+P IDFVVV
Sbjct 61 DAILLGAIGDPSVPPGILERGLLLTMRFALDHHVNLRPSRRYPGVTSPLAGDPEIDFVVV 120
Query 121 REGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVHKTN 180
REGTEGPYTGNGGAIRVGTP+EVATEVSVNT FGV RVV +AF RA++RRK LTLVHKTN
Sbjct 121 REGTEGPYTGNGGAIRVGTPHEVATEVSVNTRFGVERVVRNAFGRAQQRRKKLTLVHKTN 180
Query 181 VLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITDL 240
VL FAG LW R V+E+G +PDV Y HVDAATI+M+TDPGRFDVIVTDNLFGDIITD+
Sbjct 181 VLGFAGSLWSRAVEEIGAEFPDVTTDYCHVDAATIYMVTDPGRFDVIVTDNLFGDIITDI 240
Query 241 AAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHLGE 300
AAAV GGIGLAASGNIDAT ANPSMFEPVHGSAPDIAGQG ADPTAAI+S ALLL HLGE
Sbjct 241 AAAVSGGIGLAASGNIDATGANPSMFEPVHGSAPDIAGQGKADPTAAILSTALLLQHLGE 300
Query 301 HDAAARVDRAVEAHLATRGSERLATSDVGERI 332
+DAAAR+++AV LA R S + TS+VG+RI
Sbjct 301 NDAAARIEKAVADDLAER-SGPVVTSEVGKRI 331
>gi|333920855|ref|YP_004494436.1| 3-isopropylmalate dehydrogenase [Amycolicicoccus subflavus DQS3-9A1]
gi|333483076|gb|AEF41636.1| 3-isopropylmalate dehydrogenase [Amycolicicoccus subflavus DQS3-9A1]
Length=338
Score = 482 bits (1241), Expect = 3e-134, Method: Compositional matrix adjust.
Identities = 248/338 (74%), Positives = 284/338 (85%), Gaps = 2/338 (0%)
Query 1 MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH 60
MKLA+I GDGIG EV AEA+KVL V P + +DLGAR ++ TGE+LP+SV+ E+R H
Sbjct 1 MKLAVIPGDGIGQEVIAEALKVLKVVAPDAETAEFDLGARLYNRTGEILPESVLEEVREH 60
Query 61 DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDFVVV 120
DAILLGAIGDPSVP GVLERGLLL+LRF LDHH+NLRP++LY GV PL+GN +D VVV
Sbjct 61 DAILLGAIGDPSVPPGVLERGLLLKLRFALDHHVNLRPSKLYSGVVGPLAGNKPVDVVVV 120
Query 121 REGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVHKTN 180
REGTEGPY GNGGA+R GTPNEVATEVSVNT FG+ RVV AF+ A RRKHLTLVHKTN
Sbjct 121 REGTEGPYIGNGGALRPGTPNEVATEVSVNTRFGIERVVRYAFDLAMTRRKHLTLVHKTN 180
Query 181 VLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITDL 240
VL+FAG LW RTVD V + YP+VEV YQH+DAATIH++TDPGRFDVIVTDNLFGDIITDL
Sbjct 181 VLSFAGALWSRTVDAVAKEYPEVEVGYQHIDAATIHLVTDPGRFDVIVTDNLFGDIITDL 240
Query 241 AAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHLGE 300
AAAV GGIGLAASGNIDA+RANPSMFEPVHGSAPDIAGQ ADPTAAI+SV LL+SHLG+
Sbjct 241 AAAVTGGIGLAASGNIDASRANPSMFEPVHGSAPDIAGQQKADPTAAILSVGLLMSHLGD 300
Query 301 HDAAARVDRAVEAHLATR--GSERLATSDVGERIAAAL 336
AA R+D AV A LA R G+ +TS++G+RIAAA+
Sbjct 301 STAAERIDAAVAADLAARESGTGGASTSEIGDRIAAAI 338
>gi|111023451|ref|YP_706423.1| 3-isopropylmalate dehydrogenase [Rhodococcus jostii RHA1]
gi|122955122|sp|Q0S2H1.1|LEU3_RHOSR RecName: Full=3-isopropylmalate dehydrogenase; AltName: Full=3-IPM-DH;
AltName: Full=Beta-IPM dehydrogenase; Short=IMDH
gi|110822981|gb|ABG98265.1| 3-isopropylmalate dehydrogenase [Rhodococcus jostii RHA1]
Length=336
Score = 478 bits (1231), Expect = 4e-133, Method: Compositional matrix adjust.
Identities = 247/336 (74%), Positives = 283/336 (85%), Gaps = 0/336 (0%)
Query 1 MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH 60
MKLA+I GDGIG EVTAEA+KVL +VP +Q T YDLGARR++ATGE+LPD+ +A +R H
Sbjct 1 MKLAVIPGDGIGVEVTAEALKVLRKLVPDLQTTEYDLGARRYNATGELLPDADLAAIREH 60
Query 61 DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDFVVV 120
DAILLGAIGDPSV GVLERGLLL +RF LDHH+NLRP++LYPG SPL+ P IDFVVV
Sbjct 61 DAILLGAIGDPSVTPGVLERGLLLNMRFALDHHVNLRPSQLYPGSKSPLAAQPDIDFVVV 120
Query 121 REGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVHKTN 180
REGTEGPYTGNGGAIRVGTP+E+ATEVS+NT FG RVV AF A+ RRKH+TL+HKTN
Sbjct 121 REGTEGPYTGNGGAIRVGTPHEIATEVSINTWFGAERVVRYAFALAQTRRKHVTLIHKTN 180
Query 181 VLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITDL 240
VL+ AG +W R V+ V YPDVE AY H+DAATI+M+TDP RFDVIVTDNLFGDIITDL
Sbjct 181 VLSNAGAIWTRAVETVSAEYPDVETAYCHIDAATIYMVTDPSRFDVIVTDNLFGDIITDL 240
Query 241 AAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHLGE 300
A AV GGIGLAASGNIDA+ NPSMFEPVHGSAPDIAGQGIADPTAAI+S ALLL HLG
Sbjct 241 AGAVTGGIGLAASGNIDASGTNPSMFEPVHGSAPDIAGQGIADPTAAILSAALLLRHLGR 300
Query 301 HDAAARVDRAVEAHLATRGSERLATSDVGERIAAAL 336
AAR++ AVEA LA+RG ++ TS+VG+RIAAAL
Sbjct 301 DGDAARIEAAVEADLASRGDSKVVTSEVGDRIAAAL 336
>gi|312140490|ref|YP_004007826.1| 3-isopropylmalate dehydrogenase leub [Rhodococcus equi 103S]
gi|311889829|emb|CBH49146.1| 3-isopropylmalate dehydrogenase LeuB [Rhodococcus equi 103S]
Length=337
Score = 477 bits (1228), Expect = 1e-132, Method: Compositional matrix adjust.
Identities = 239/337 (71%), Positives = 281/337 (84%), Gaps = 1/337 (0%)
Query 1 MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH 60
MKLA+I GDGIG EVTAEA+KVL +VP V+ T +DLGA+R++ TG++LPD+ + +R H
Sbjct 1 MKLAVIPGDGIGVEVTAEALKVLRKLVPDVETTEFDLGAKRYNETGDLLPDAELDAIRQH 60
Query 61 DAILLGAIGDPS-VPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDFVV 119
DAILLGAIGDP V G+LERGLLL +RF LDHH+NLRPAR YP +SPL+ NP IDFVV
Sbjct 61 DAILLGAIGDPRFVAPGILERGLLLNMRFLLDHHVNLRPARTYPQSSSPLAANPDIDFVV 120
Query 120 VREGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVHKT 179
VREGTEGPYTGNGG+IR+GTP+EVATEVSVNT FG RVV A+E A++RR HLTL+HKT
Sbjct 121 VREGTEGPYTGNGGSIRIGTPHEVATEVSVNTWFGAERVVRAAYELAQKRRGHLTLIHKT 180
Query 180 NVLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITD 239
NVL+ AG +W R ++ VG YPDVE AY H+DAATI+M+TDP RFDVIVTDNLFGDIITD
Sbjct 181 NVLSNAGRIWTRAMETVGAEYPDVETAYCHIDAATIYMVTDPARFDVIVTDNLFGDIITD 240
Query 240 LAAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHLG 299
LA AV GGIGLAAS NIDA+ NPSMFEPVHGSAPDIAGQGIADPTAAI+S A+LL HLG
Sbjct 241 LAGAVTGGIGLAASANIDASGTNPSMFEPVHGSAPDIAGQGIADPTAAILSAAMLLRHLG 300
Query 300 EHDAAARVDRAVEAHLATRGSERLATSDVGERIAAAL 336
D AAR++ AVEA LA+RG + T++VG+RIAAAL
Sbjct 301 REDDAARIEAAVEADLASRGDGPIVTTEVGDRIAAAL 337
>gi|226365952|ref|YP_002783735.1| 3-isopropylmalate dehydrogenase [Rhodococcus opacus B4]
gi|254808556|sp|C1B2M3.1|LEU3_RHOOB RecName: Full=3-isopropylmalate dehydrogenase; AltName: Full=3-IPM-DH;
AltName: Full=Beta-IPM dehydrogenase; Short=IMDH
gi|226244442|dbj|BAH54790.1| 3-isopropylmalate dehydrogenase [Rhodococcus opacus B4]
Length=336
Score = 477 bits (1227), Expect = 1e-132, Method: Compositional matrix adjust.
Identities = 246/336 (74%), Positives = 283/336 (85%), Gaps = 0/336 (0%)
Query 1 MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH 60
MKLA+I GDGIG EVTAEA+KVL +VP ++ T YDLGARR++ATGE+LPD+ +A +R H
Sbjct 1 MKLAVIPGDGIGVEVTAEALKVLRKLVPDLETTEYDLGARRYNATGELLPDADLAAIREH 60
Query 61 DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDFVVV 120
DAILLGAIGDPSV GVLERGLLL +RF LDHH+NLRP++LYPG SPL+ P IDFVVV
Sbjct 61 DAILLGAIGDPSVTPGVLERGLLLNMRFALDHHVNLRPSQLYPGSKSPLAAQPDIDFVVV 120
Query 121 REGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVHKTN 180
REGTEGPYTGNGGAIRVGTP+E+ATEVS+NT FG RVV AF A+ RRKH+TL+HKTN
Sbjct 121 REGTEGPYTGNGGAIRVGTPHEIATEVSINTWFGAERVVRYAFALAQTRRKHVTLIHKTN 180
Query 181 VLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITDL 240
VL+ AG +W R V+ V YPDVE AY H+DAATI+M+TDP RFDVIVTDNLFGDIITDL
Sbjct 181 VLSNAGAIWTRAVETVSAEYPDVETAYCHIDAATIYMVTDPSRFDVIVTDNLFGDIITDL 240
Query 241 AAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHLGE 300
A AV GGIGLAASGNIDA+ NPSMFEPVHGSAPDIAGQGIADPTAAI+S ALLL HLG
Sbjct 241 AGAVTGGIGLAASGNIDASGTNPSMFEPVHGSAPDIAGQGIADPTAAILSAALLLRHLGR 300
Query 301 HDAAARVDRAVEAHLATRGSERLATSDVGERIAAAL 336
AAR++ AVEA LA+RG ++ TS+VG+RIAAAL
Sbjct 301 DGDAARIETAVEADLASRGDSKVVTSEVGDRIAAAL 336
>gi|325675892|ref|ZP_08155576.1| 3-isopropylmalate dehydrogenase [Rhodococcus equi ATCC 33707]
gi|325553863|gb|EGD23541.1| 3-isopropylmalate dehydrogenase [Rhodococcus equi ATCC 33707]
Length=337
Score = 476 bits (1225), Expect = 2e-132, Method: Compositional matrix adjust.
Identities = 238/337 (71%), Positives = 281/337 (84%), Gaps = 1/337 (0%)
Query 1 MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH 60
MKLA+I GDGIG EVTAEA+KVL +VP V+ T +DLGA+R++ TG++LPD+ + +R H
Sbjct 1 MKLAVIPGDGIGVEVTAEALKVLRKLVPDVETTEFDLGAKRYNETGDLLPDAELDAIRQH 60
Query 61 DAILLGAIGDPS-VPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDFVV 119
DAILLGAIGDP V G+LERGLLL +RF LDHH+NLRPAR YP +SPL+ NP IDFVV
Sbjct 61 DAILLGAIGDPRFVAPGILERGLLLNMRFLLDHHVNLRPARTYPQSSSPLAANPDIDFVV 120
Query 120 VREGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVHKT 179
VREGTEGPYTGNGG+IR+GTP+EVATEVSVNT FG RVV A+E A++RR HLTL+HKT
Sbjct 121 VREGTEGPYTGNGGSIRIGTPHEVATEVSVNTWFGAERVVRAAYELAQKRRGHLTLIHKT 180
Query 180 NVLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITD 239
NVL+ AG +W R ++ VG YPDVE AY H+DAATI+M+TDP RFDVIVTDNLFGDIITD
Sbjct 181 NVLSNAGRIWTRAMETVGAEYPDVETAYCHIDAATIYMVTDPARFDVIVTDNLFGDIITD 240
Query 240 LAAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHLG 299
LA AV GGIGLAAS NIDA+ NPSMFEPVHGSAPDIAGQGIADPTAAI+S A+LL HLG
Sbjct 241 LAGAVTGGIGLAASANIDASGTNPSMFEPVHGSAPDIAGQGIADPTAAILSAAMLLRHLG 300
Query 300 EHDAAARVDRAVEAHLATRGSERLATSDVGERIAAAL 336
D AAR++ AVEA LA+RG + T++VG+RIAAA+
Sbjct 301 REDDAARIEAAVEADLASRGDGPIVTTEVGDRIAAAV 337
>gi|227504456|ref|ZP_03934505.1| 3-isopropylmalate dehydrogenase [Corynebacterium striatum ATCC
6940]
gi|227199104|gb|EEI79152.1| 3-isopropylmalate dehydrogenase [Corynebacterium striatum ATCC
6940]
Length=338
Score = 474 bits (1220), Expect = 9e-132, Method: Compositional matrix adjust.
Identities = 238/338 (71%), Positives = 283/338 (84%), Gaps = 3/338 (0%)
Query 1 MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH 60
MKLA+I GDGIGPEVTAEA+KVL+AV ++ T YDLGARR+ GE+L D+ +A +R H
Sbjct 1 MKLAVIGGDGIGPEVTAEALKVLNAVRDDIETTEYDLGARRYLRNGELLTDADLASIREH 60
Query 61 DAILLGAIGDP-SVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPG-IDFV 118
DAILLGAIG+P VP G+LERGLLL++RF LDHH+NLRP++LYP SPL+ NPG IDFV
Sbjct 61 DAILLGAIGEPGQVPPGILERGLLLKMRFALDHHVNLRPSKLYPTATSPLA-NPGEIDFV 119
Query 119 VVREGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVHK 178
VVREGTEG Y GNGG +R GTP+EVA+EVS NT FGV RVV DAFERA RRKH+TLVHK
Sbjct 120 VVREGTEGLYCGNGGTLREGTPHEVASEVSQNTRFGVERVVRDAFERAMGRRKHVTLVHK 179
Query 179 TNVLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIIT 238
TNVL AGGLW RTV+EV + YP+V V Y H+DAATI+M+TDPGR+DVIVTDNLFGDI+T
Sbjct 180 TNVLVNAGGLWQRTVEEVAKEYPEVTVDYNHIDAATIYMVTDPGRYDVIVTDNLFGDILT 239
Query 239 DLAAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHL 298
DLA AV GGIGLAASGNIDA+ NPSMFEPVHGSAPDIAG+GIADPTAAI+S A+LL H+
Sbjct 240 DLAGAVTGGIGLAASGNIDASGTNPSMFEPVHGSAPDIAGKGIADPTAAILSAAMLLRHI 299
Query 299 GEHDAAARVDRAVEAHLATRGSERLATSDVGERIAAAL 336
G+ A R++ AV A ++ RGSE+L T+++G+RIAAAL
Sbjct 300 GDETNAVRIEEAVAADVSARGSEQLGTTEIGDRIAAAL 337
>gi|296140549|ref|YP_003647792.1| 3-isopropylmalate dehydrogenase [Tsukamurella paurometabola DSM
20162]
gi|296028683|gb|ADG79453.1| 3-isopropylmalate dehydrogenase [Tsukamurella paurometabola DSM
20162]
Length=339
Score = 464 bits (1193), Expect = 1e-128, Method: Compositional matrix adjust.
Identities = 238/338 (71%), Positives = 269/338 (80%), Gaps = 3/338 (0%)
Query 1 MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH 60
MKLA+I GDGIGPEV AEA+KVL V ++ T YDLG+RR+ GE+L D +A LR H
Sbjct 1 MKLAVIGGDGIGPEVVAEALKVLRVVAGDIETTDYDLGSRRYERNGELLTDEDLASLREH 60
Query 61 DAILLGAIGDP-SVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPG-IDFV 118
DAILLGAIGDP VP GVLERGLLL++RF LDHH+NLRP++L+PGV SPL NPG IDFV
Sbjct 61 DAILLGAIGDPRKVPPGVLERGLLLKMRFALDHHVNLRPSKLFPGVESPLK-NPGEIDFV 119
Query 119 VVREGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVHK 178
VVREGTEG YTGNGGAIRVGTP+EVA E SVNT FG RVV AF A+ RRK LTLVHK
Sbjct 120 VVREGTEGAYTGNGGAIRVGTPHEVANETSVNTRFGAERVVRYAFALAQTRRKKLTLVHK 179
Query 179 TNVLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIIT 238
TNVL + GGLW RTVDEVG +PDV V Y H+DAATI+++TDP RFDVIVTDNLFGDI+T
Sbjct 180 TNVLVYGGGLWQRTVDEVGREFPDVAVDYSHIDAATIYLVTDPSRFDVIVTDNLFGDILT 239
Query 239 DLAAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHL 298
D A A+ GGIGLAASGNIDAT NPSMFEPVHGSAPDI GQGIADPTAAI+S A+LL HL
Sbjct 240 DEAGAISGGIGLAASGNIDATGTNPSMFEPVHGSAPDIVGQGIADPTAAILSAAMLLRHL 299
Query 299 GEHDAAARVDRAVEAHLATRGSERLATSDVGERIAAAL 336
G D A R++ AV A L RG + T +VG+RIAA L
Sbjct 300 GNEDGAQRIETAVAADLEARGDAPVRTVEVGDRIAATL 337
>gi|213964557|ref|ZP_03392757.1| tartrate dehydrogenase/decarboxylase [Corynebacterium amycolatum
SK46]
gi|213952750|gb|EEB64132.1| tartrate dehydrogenase/decarboxylase [Corynebacterium amycolatum
SK46]
Length=344
Score = 462 bits (1189), Expect = 4e-128, Method: Compositional matrix adjust.
Identities = 236/338 (70%), Positives = 275/338 (82%), Gaps = 3/338 (0%)
Query 1 MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH 60
+K+A+I GDGIG EVTAEA+KVL A + T YDLG+RR+ GE+L D+ + LR H
Sbjct 7 LKIAVIPGDGIGTEVTAEALKVLKAAIGEFDTTEYDLGSRRYLRNGELLTDADLDSLREH 66
Query 61 DAILLGAIGDP-SVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPG-IDFV 118
DAILLGAIGDP +VP GVLERGLLL++RF LDHH+NLRP++L+PGV SPL NPG IDFV
Sbjct 67 DAILLGAIGDPANVPPGVLERGLLLKMRFALDHHVNLRPSKLFPGVESPLK-NPGEIDFV 125
Query 119 VVREGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVHK 178
VVREGTEG YTGNGGAIRVGTP+EVA E SVNT FG RVV AFE A RRK LTLVHK
Sbjct 126 VVREGTEGAYTGNGGAIRVGTPHEVANETSVNTRFGAERVVRYAFELAMTRRKKLTLVHK 185
Query 179 TNVLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIIT 238
TNVL GG+W RTVDEV + YP+V+V Y H+DAATI+++T+P RFDVIVTDNLFGDIIT
Sbjct 186 TNVLVHGGGMWQRTVDEVAKEYPEVDVDYSHIDAATIYLVTNPSRFDVIVTDNLFGDIIT 245
Query 239 DLAAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHL 298
D A AV GGIGLAASGNIDA+ NPSMFEPVHGSAPDIAG+GIADPTAAI+S A++L HL
Sbjct 246 DEAGAVSGGIGLAASGNIDASNTNPSMFEPVHGSAPDIAGKGIADPTAAILSGAMMLRHL 305
Query 299 GEHDAAARVDRAVEAHLATRGSERLATSDVGERIAAAL 336
G A R++ AVEA +ATRGS + T++VG+RIAAAL
Sbjct 306 GREQDAQRIEAAVEADMATRGSGPIKTTEVGDRIAAAL 343
>gi|300783618|ref|YP_003763909.1| 3-isopropylmalate dehydrogenase [Amycolatopsis mediterranei U32]
gi|299793132|gb|ADJ43507.1| 3-isopropylmalate dehydrogenase [Amycolatopsis mediterranei U32]
gi|340525008|gb|AEK40213.1| 3-isopropylmalate dehydrogenase [Amycolatopsis mediterranei S699]
Length=345
Score = 462 bits (1188), Expect = 4e-128, Method: Compositional matrix adjust.
Identities = 246/336 (74%), Positives = 282/336 (84%), Gaps = 2/336 (0%)
Query 1 MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH 60
M+LA+I GDGIGPEV +EA+KVL VVP + T+YDLGA R+H+TGE+LP+SV+ ELR H
Sbjct 1 MRLAVIPGDGIGPEVVSEALKVLGEVVPTAEITNYDLGAARWHSTGELLPESVLGELRQH 60
Query 61 DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDFVVV 120
DAILLGA+GDPSVPSG+LERGLLLRLRFE+DHH+NLRPARLYPGV PL+ +D VVV
Sbjct 61 DAILLGAVGDPSVPSGILERGLLLRLRFEMDHHVNLRPARLYPGVRGPLADAGDVDMVVV 120
Query 121 REGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRR-RKHLTLVHKT 179
REGTEGPY G GG IR T +E+ATEVSVNTAFGVRRVVADAF RA R RKHLTLVHKT
Sbjct 121 REGTEGPYAGTGGLIRKDTEHEIATEVSVNTAFGVRRVVADAFSRAEARPRKHLTLVHKT 180
Query 180 NVLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITD 239
NVL+FAG LW R V+EV +PDV VAY HVDAATIH++TDP RFDVIVTDNLFGDIITD
Sbjct 181 NVLSFAGSLWSRIVEEVSLEHPDVTVAYSHVDAATIHLVTDPSRFDVIVTDNLFGDIITD 240
Query 240 LAAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHLG 299
LAAAV GGIGLAASGN+D TR NPSMFEPVHGSAPDIAGQG+ADPTAA++SVALLL HLG
Sbjct 241 LAAAVTGGIGLAASGNLDMTRRNPSMFEPVHGSAPDIAGQGLADPTAAVLSVALLLDHLG 300
Query 300 EHDAAARVDRAVEAHLATRGSERL-ATSDVGERIAA 334
+ +AA R++ +V LATR AT +G+R+AA
Sbjct 301 QKEAARRIEASVAFDLATRDQASPGATQAIGDRLAA 336
>gi|19552506|ref|NP_600508.1| 3-isopropylmalate dehydrogenase [Corynebacterium glutamicum ATCC
13032]
gi|62390172|ref|YP_225574.1| 3-isopropylmalate dehydrogenase [Corynebacterium glutamicum ATCC
13032]
gi|2497262|sp|P94631.1|LEU3_CORGL RecName: Full=3-isopropylmalate dehydrogenase; AltName: Full=3-IPM-DH;
AltName: Full=Beta-IPM dehydrogenase; Short=IMDH
gi|1694761|emb|CAA70767.1| 3-isopropylmalate dehydrogenase [Corynebacterium glutamicum]
gi|21324054|dbj|BAB98679.1| Isocitrate/isopropylmalate dehydrogenase [Corynebacterium glutamicum
ATCC 13032]
gi|41325508|emb|CAF19988.1| 3-ISOPROPYLMALATE DEHYDROGENASE [Corynebacterium glutamicum ATCC
13032]
Length=340
Score = 462 bits (1188), Expect = 4e-128, Method: Compositional matrix adjust.
Identities = 237/339 (70%), Positives = 276/339 (82%), Gaps = 4/339 (1%)
Query 1 MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH 60
MKLA+I GDGIGPEVTAEA+KVL+AV ++ T YDLGARR+ GE+L D +A LR H
Sbjct 1 MKLAVIGGDGIGPEVTAEALKVLNAVRDDIETTDYDLGARRYLKNGELLTDEDLASLREH 60
Query 61 DAILLGAIGDP-SVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPG-IDFV 118
DAILLGAIG P SVP G+LERGLLL++RF LDHH+NLRP++LY GV SPL NPG IDFV
Sbjct 61 DAILLGAIGAPGSVPPGILERGLLLKMRFALDHHVNLRPSKLYDGVESPLR-NPGKIDFV 119
Query 119 VVREGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVHK 178
VVREGTEG YTGNGGAIRVGTP+E+A E SVNT +G RV+ AFE A+ RRK LTLVHK
Sbjct 120 VVREGTEGAYTGNGGAIRVGTPHEIANETSVNTRYGAERVIRYAFELAQSRRKKLTLVHK 179
Query 179 TNVLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIIT 238
TNVL GGLW RTVDEV + YP+V V Y H+DAATI+++TDP RFDVIVTDNLFGDI+T
Sbjct 180 TNVLVHGGGLWQRTVDEVAKEYPEVAVDYNHIDAATIYLVTDPSRFDVIVTDNLFGDILT 239
Query 239 DLAAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHL 298
D A AV GGIGLAASGNIDAT NPSMFEPVHGSAPDIAGQGIADPTAAI+S A+LL HL
Sbjct 240 DEAGAVSGGIGLAASGNIDATGTNPSMFEPVHGSAPDIAGQGIADPTAAILSAAMLLRHL 299
Query 299 GEHDAAARVDRAVEAHLATR-GSERLATSDVGERIAAAL 336
G+ D A R++ A+ A +A R S+ ++T++VG+RI AL
Sbjct 300 GDEDNAVRIETAIAADVAGRDNSQPISTTEVGDRIVKAL 338
>gi|296119583|ref|ZP_06838141.1| 3-isopropylmalate dehydrogenase [Corynebacterium ammoniagenes
DSM 20306]
gi|295967466|gb|EFG80733.1| 3-isopropylmalate dehydrogenase [Corynebacterium ammoniagenes
DSM 20306]
Length=345
Score = 461 bits (1187), Expect = 6e-128, Method: Compositional matrix adjust.
Identities = 234/338 (70%), Positives = 276/338 (82%), Gaps = 3/338 (0%)
Query 1 MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH 60
MKLA+I GDGIGPEVTAEAVKVL AV ++ T +DLGA R+ GE+L D +A LR H
Sbjct 8 MKLAVIGGDGIGPEVTAEAVKVLRAVRDDIETTDFDLGATRYLNNGELLTDEDLASLREH 67
Query 61 DAILLGAIGDP-SVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPG-IDFV 118
DAILLGA+G P VP G+LERGLLL+LRF LDHH+NLRP++LYP SPL+ NPG IDFV
Sbjct 68 DAILLGAVGAPGKVPPGILERGLLLKLRFALDHHVNLRPSKLYPTAVSPLA-NPGEIDFV 126
Query 119 VVREGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVHK 178
VVREGTEG Y GNGG +R GT +EVA+EVS NT +GV RVV DAF RA+ RRK LTLVHK
Sbjct 127 VVREGTEGLYAGNGGTLRQGTEHEVASEVSQNTRYGVERVVRDAFNRAQGRRKKLTLVHK 186
Query 179 TNVLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIIT 238
TNVL AG LW RTV++V + +P+VEV Y H+DAATI+M+TDP R+DVIVTDNLFGDI+T
Sbjct 187 TNVLVNAGDLWQRTVEDVAKEFPEVEVDYNHIDAATIYMVTDPERYDVIVTDNLFGDILT 246
Query 239 DLAAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHL 298
DLA AV GGIGLAASGNID+T+ NPSMFEPVHGSAPDIAGQGIADPTAAI+S ALLL HL
Sbjct 247 DLAGAVAGGIGLAASGNIDSTKTNPSMFEPVHGSAPDIAGQGIADPTAAILSTALLLRHL 306
Query 299 GEHDAAARVDRAVEAHLATRGSERLATSDVGERIAAAL 336
G+ D A R+++AV ++ RG E++ T +VG+RIAAAL
Sbjct 307 GDEDNAQRIEKAVAEDVSARGDEQVKTVEVGDRIAAAL 344
>gi|145295427|ref|YP_001138248.1| 3-isopropylmalate dehydrogenase [Corynebacterium glutamicum R]
gi|166989776|sp|A4QDP9.1|LEU3_CORGB RecName: Full=3-isopropylmalate dehydrogenase; AltName: Full=3-IPM-DH;
AltName: Full=Beta-IPM dehydrogenase; Short=IMDH
gi|140845347|dbj|BAF54346.1| hypothetical protein [Corynebacterium glutamicum R]
gi|344046062|gb|EGV41729.1| 3-isopropylmalate dehydrogenase [Corynebacterium glutamicum S9114]
Length=340
Score = 460 bits (1184), Expect = 1e-127, Method: Compositional matrix adjust.
Identities = 237/339 (70%), Positives = 275/339 (82%), Gaps = 4/339 (1%)
Query 1 MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH 60
MKLA+I GDGIGPEVTAEA+KVL+AV ++ T YDLGARR+ GE+L D +A LR H
Sbjct 1 MKLAVIGGDGIGPEVTAEALKVLNAVRDDIETTDYDLGARRYLKNGELLTDEDLASLREH 60
Query 61 DAILLGAIGDP-SVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPG-IDFV 118
DAILLGAIG P SVP G+LERGLLL++RF LDHH+NLRP++LY GV SPL NPG IDFV
Sbjct 61 DAILLGAIGAPGSVPPGILERGLLLKMRFALDHHVNLRPSKLYDGVESPLR-NPGKIDFV 119
Query 119 VVREGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVHK 178
VVREGTEG YTGNGGAIRVGT +E+A E SVNT +G RV+ AFE A+ RRK LTLVHK
Sbjct 120 VVREGTEGAYTGNGGAIRVGTAHEIANETSVNTRYGAERVIRYAFELAQSRRKKLTLVHK 179
Query 179 TNVLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIIT 238
TNVL GGLW RTVDEV + YP+V V Y H+DAATI++ITDP RFDVIVTDNLFGDI+T
Sbjct 180 TNVLVHGGGLWQRTVDEVAKEYPEVAVDYNHIDAATIYLITDPSRFDVIVTDNLFGDILT 239
Query 239 DLAAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHL 298
D A AV GGIGLAASGNIDAT NPSMFEPVHGSAPDIAGQGIADPTAAI+S A+LL HL
Sbjct 240 DEAGAVSGGIGLAASGNIDATGTNPSMFEPVHGSAPDIAGQGIADPTAAILSAAMLLRHL 299
Query 299 GEHDAAARVDRAVEAHLATR-GSERLATSDVGERIAAAL 336
G+ D A R++ A+ A +A R S+ ++T++VG+RI AL
Sbjct 300 GDEDNAVRIETAIAADVAGRDNSQPISTTEVGDRIVKAL 338
>gi|227832960|ref|YP_002834667.1| 3-isopropylmalate dehydrogenase [Corynebacterium aurimucosum
ATCC 700975]
gi|262182553|ref|ZP_06041974.1| 3-isopropylmalate dehydrogenase [Corynebacterium aurimucosum
ATCC 700975]
gi|254808553|sp|C3PFX5.1|LEU3_CORA7 RecName: Full=3-isopropylmalate dehydrogenase; AltName: Full=3-IPM-DH;
AltName: Full=Beta-IPM dehydrogenase; Short=IMDH
gi|227453976|gb|ACP32729.1| 3-isopropylmalate dehydrogenase [Corynebacterium aurimucosum
ATCC 700975]
Length=339
Score = 460 bits (1184), Expect = 1e-127, Method: Compositional matrix adjust.
Identities = 236/338 (70%), Positives = 277/338 (82%), Gaps = 3/338 (0%)
Query 1 MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH 60
MKLA+I GDGIGPEVTAEA+KVL AV V+ T YDLGARR+ GE+L D+ A LR H
Sbjct 1 MKLAVIGGDGIGPEVTAEALKVLRAVRQDVEVTDYDLGARRYLRNGELLSDADFASLREH 60
Query 61 DAILLGAIGDP-SVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPG-IDFV 118
DAILLGAIG P VP GVLERGLLL++RF LDHH+NLRP++LYP SPL+ NPG IDFV
Sbjct 61 DAILLGAIGAPGEVPPGVLERGLLLKMRFALDHHVNLRPSKLYPTSTSPLA-NPGDIDFV 119
Query 119 VVREGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVHK 178
VVREGTEG Y GNGG +R GT +EVA+EVS NT FGV RVV DAF+RA RRKH+TLVHK
Sbjct 120 VVREGTEGLYCGNGGTLREGTEHEVASEVSQNTRFGVERVVRDAFQRAMGRRKHVTLVHK 179
Query 179 TNVLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIIT 238
TNVL AGGLW RTV+EV + +P+V V Y H+DAATI+M+TDP R+DVIVTDNLFGDI+T
Sbjct 180 TNVLVNAGGLWQRTVNEVAQEFPEVTVDYNHIDAATIYMVTDPARYDVIVTDNLFGDILT 239
Query 239 DLAAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHL 298
DLA AV GGIGLAASGNIDA+ ANPSMFEPVHGSAPDIAG+GIADPTAAI+S A+LL HL
Sbjct 240 DLAGAVTGGIGLAASGNIDASGANPSMFEPVHGSAPDIAGKGIADPTAAILSAAMLLRHL 299
Query 299 GEHDAAARVDRAVEAHLATRGSERLATSDVGERIAAAL 336
G+ + A R++ AV A ++ RG + T+++G+RIAAAL
Sbjct 300 GDEENAVRIEEAVAADVSARGDAQARTTEIGDRIAAAL 337
>gi|331695674|ref|YP_004331913.1| 3-isopropylmalate dehydrogenase [Pseudonocardia dioxanivorans
CB1190]
gi|326950363|gb|AEA24060.1| 3-isopropylmalate dehydrogenase [Pseudonocardia dioxanivorans
CB1190]
Length=346
Score = 459 bits (1182), Expect = 2e-127, Method: Compositional matrix adjust.
Identities = 248/336 (74%), Positives = 280/336 (84%), Gaps = 2/336 (0%)
Query 1 MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH 60
M+LA+I GDGIGPEV EA+KVL+ V PG + T+YDLGA R+H+TGE+LP+SV+ ELR H
Sbjct 1 MRLAVIPGDGIGPEVIDEALKVLNEVAPGAETTNYDLGAARWHSTGELLPESVLTELRGH 60
Query 61 DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDFVVV 120
DAILLGA+GDPSVPSG+LERGLLLRLRFELDHH+NLRPARLYPGV PL+GNP ID VVV
Sbjct 61 DAILLGAVGDPSVPSGILERGLLLRLRFELDHHVNLRPARLYPGVRGPLAGNPEIDLVVV 120
Query 121 REGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRR-RKHLTLVHKT 179
REGTEGPY G GG +R TP EVATEVS NTAFG+ RVV DAF RA RR RKHLTLVHKT
Sbjct 121 REGTEGPYVGTGGLLRKDTPQEVATEVSTNTAFGIERVVRDAFARAERRPRKHLTLVHKT 180
Query 180 NVLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITD 239
NVL FAG LW R V+EV +PDV VAYQHVD+ TIH++TDP R+DVIVTDNLFGDI+TD
Sbjct 181 NVLAFAGALWSRIVEEVSLEHPDVTVAYQHVDSTTIHLVTDPSRYDVIVTDNLFGDILTD 240
Query 240 LAAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHLG 299
LAAAV GGIGLAASGNIDA+ NPSMFEPVHGSAPDIAGQGIADPTAA++SVALLL HLG
Sbjct 241 LAAAVTGGIGLAASGNIDASGRNPSMFEPVHGSAPDIAGQGIADPTAAVLSVALLLDHLG 300
Query 300 EHDAAARVDRAVEAHLATRG-SERLATSDVGERIAA 334
DAA R++ AV LATR T +G+R+AA
Sbjct 301 RSDAARRIEAAVAFDLATRDHGANSHTRSIGDRLAA 336
>gi|300858318|ref|YP_003783301.1| 3-isopropylmalate dehydrogenase [Corynebacterium pseudotuberculosis
FRC41]
gi|300685772|gb|ADK28694.1| 3-isopropylmalate dehydrogenase [Corynebacterium pseudotuberculosis
FRC41]
gi|302206034|gb|ADL10376.1| 3-isopropylmalate dehydrogenase [Corynebacterium pseudotuberculosis
C231]
gi|302330587|gb|ADL20781.1| 3-isopropylmalate dehydrogenase [Corynebacterium pseudotuberculosis
1002]
gi|308276271|gb|ADO26170.1| 3-isopropylmalate dehydrogenase [Corynebacterium pseudotuberculosis
I19]
gi|341824705|gb|AEK92226.1| 3-isopropylmalate dehydrogenase [Corynebacterium pseudotuberculosis
PAT10]
Length=339
Score = 459 bits (1181), Expect = 3e-127, Method: Compositional matrix adjust.
Identities = 233/338 (69%), Positives = 275/338 (82%), Gaps = 3/338 (0%)
Query 1 MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH 60
MKLA+I GDGIGPEVTAEA+KVL AV + T++DLGARR+ TGE+L + + +LR H
Sbjct 1 MKLAVIGGDGIGPEVTAEALKVLQAVRDDIHVTNFDLGARRYLRTGELLTQTDLDQLREH 60
Query 61 DAILLGAIGDP-SVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPG-IDFV 118
DAILLGAIG P VPSGVLERGLLL++RFELDHH+NLRP++LYP SPLS NPG IDFV
Sbjct 61 DAILLGAIGAPGEVPSGVLERGLLLKMRFELDHHVNLRPSKLYPKSISPLS-NPGDIDFV 119
Query 119 VVREGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVHK 178
VVREGTEG Y GNGG +R GT EVA+EVS NT +GV RVV DAF RA+ RRKHLTLVHK
Sbjct 120 VVREGTEGLYCGNGGVLRRGTEYEVASEVSQNTRYGVARVVRDAFRRAQERRKHLTLVHK 179
Query 179 TNVLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIIT 238
TNVL AGGLW RTVDEV + +P+V+V Y H+DAATI+M+T+P R+DVIVTDNLFGDI+T
Sbjct 180 TNVLVNAGGLWQRTVDEVSKEFPEVQVDYNHIDAATIYMVTEPSRYDVIVTDNLFGDILT 239
Query 239 DLAAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHL 298
DLA AV GGIGLAAS NID + NPSMFEPVHGSAPDIAGQGIADPTAAI+S +LL HL
Sbjct 240 DLAGAVSGGIGLAASANIDTSGINPSMFEPVHGSAPDIAGQGIADPTAAILSAGMLLRHL 299
Query 299 GEHDAAARVDRAVEAHLATRGSERLATSDVGERIAAAL 336
G+ + A+R+D AV ++ R ++ TS+VG RIAA+L
Sbjct 300 GDEENASRIDNAVAMDISARVGVKMVTSEVGNRIAASL 337
>gi|325003698|ref|ZP_08124810.1| 3-isopropylmalate dehydrogenase [Pseudonocardia sp. P1]
Length=346
Score = 459 bits (1181), Expect = 3e-127, Method: Compositional matrix adjust.
Identities = 246/336 (74%), Positives = 283/336 (85%), Gaps = 2/336 (0%)
Query 1 MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH 60
M+LA+I GDGIGPEV EA+KVL V V+ T YDLGA R+H+TGE+LP++V+ E++ H
Sbjct 1 MRLAVIPGDGIGPEVINEALKVLGEVARDVETTEYDLGAARWHSTGELLPETVLTEIKQH 60
Query 61 DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDFVVV 120
DAILLGA+GDPSVPSG+LERGLLLRLRFELDHH+NLRPARLYPGV SPL+GN ID VVV
Sbjct 61 DAILLGAVGDPSVPSGILERGLLLRLRFELDHHVNLRPARLYPGVRSPLAGNAEIDMVVV 120
Query 121 REGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRR-RKHLTLVHKT 179
REGTEGPY G GG +R TP+EVATEVS NTAFG+ RVV DAF RA+RR R+HLTLVHKT
Sbjct 121 REGTEGPYVGTGGLLRKDTPHEVATEVSQNTAFGIERVVRDAFARAQRRPRRHLTLVHKT 180
Query 180 NVLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITD 239
NVLT+AG LW R V+EV YP+V VAYQHVD+ TIHM+TDPGR+DVIVTDNLFGDI+TD
Sbjct 181 NVLTYAGALWSRIVEEVSLEYPEVSVAYQHVDSTTIHMVTDPGRYDVIVTDNLFGDILTD 240
Query 240 LAAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHLG 299
LAAAV GGIGLAASGN+DA+R NPSMFEPVHGSAPDIAGQGIADPTAA++SVALLL HLG
Sbjct 241 LAAAVTGGIGLAASGNLDASRTNPSMFEPVHGSAPDIAGQGIADPTAAVLSVALLLDHLG 300
Query 300 EHDAAARVDRAVEAHLATRGSERLA-TSDVGERIAA 334
D+A RV+ AV LATR TS +G+R+AA
Sbjct 301 HPDSARRVEAAVAFDLATRDHAATGNTSSIGDRLAA 336
>gi|256380007|ref|YP_003103667.1| 3-isopropylmalate dehydrogenase [Actinosynnema mirum DSM 43827]
gi|255924310|gb|ACU39821.1| 3-isopropylmalate dehydrogenase [Actinosynnema mirum DSM 43827]
Length=345
Score = 458 bits (1178), Expect = 6e-127, Method: Compositional matrix adjust.
Identities = 247/336 (74%), Positives = 285/336 (85%), Gaps = 2/336 (0%)
Query 1 MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH 60
M+LA+I GDGIGPEV AEA+KVL VVP + T YDLGA R+HATGE+LP+SV+ ELR H
Sbjct 1 MRLAVIPGDGIGPEVVAEALKVLGEVVPAAEITRYDLGAARWHATGELLPESVLGELRQH 60
Query 61 DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDFVVV 120
DAILLGA+GDPSVPSG+LERGLLLRLRFELDHH+NLRPARLYPGV SP++ P ID VVV
Sbjct 61 DAILLGAVGDPSVPSGILERGLLLRLRFELDHHVNLRPARLYPGVRSPIADPPEIDMVVV 120
Query 121 REGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRR-RKHLTLVHKT 179
REGTEG Y GNGG +R TP+E+ATEVS+NT+FGV RVV DAF RA R RKHLTLVHKT
Sbjct 121 REGTEGLYAGNGGLLRKDTPHEIATEVSINTSFGVERVVRDAFARAANRPRKHLTLVHKT 180
Query 180 NVLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITD 239
NVLT AG LW R V+EV +PDV VAYQHVDAATIH++TDPGR+DVIVTDNLFGDI+TD
Sbjct 181 NVLTHAGSLWSRVVEEVSLQHPDVTVAYQHVDAATIHLVTDPGRYDVIVTDNLFGDILTD 240
Query 240 LAAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHLG 299
LAAAV GGIGLAASGN+D TR NPSMFEPVHGSAPDIAGQG+ADPTAA++SVAL+L HLG
Sbjct 241 LAAAVTGGIGLAASGNLDVTRRNPSMFEPVHGSAPDIAGQGVADPTAAVLSVALMLDHLG 300
Query 300 EHDAAARVDRAVEAHLATRG-SERLATSDVGERIAA 334
EH++A R++ +V LATR + AT +G+R+AA
Sbjct 301 EHESARRIEASVAFDLATRDHASPGATYAIGDRLAA 336
>gi|38233699|ref|NP_939466.1| 3-isopropylmalate dehydrogenase [Corynebacterium diphtheriae
NCTC 13129]
gi|81564874|sp|Q6NHM7.1|LEU3_CORDI RecName: Full=3-isopropylmalate dehydrogenase; AltName: Full=3-IPM-DH;
AltName: Full=Beta-IPM dehydrogenase; Short=IMDH
gi|38199960|emb|CAE49628.1| 3-isopropylmalate dehydrogenase [Corynebacterium diphtheriae]
Length=339
Score = 456 bits (1173), Expect = 2e-126, Method: Compositional matrix adjust.
Identities = 233/338 (69%), Positives = 274/338 (82%), Gaps = 3/338 (0%)
Query 1 MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH 60
MKLA+I GDGIGPEVTAEA+KVL+AV ++ T YDLGARR+ GE+L D+ + LR H
Sbjct 1 MKLAVIGGDGIGPEVTAEALKVLNAVRDDIEVTDYDLGARRYLRNGELLADADLVSLREH 60
Query 61 DAILLGAIGDP-SVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPG-IDFV 118
DAILLGAIG P VP GVLERGLLL++RF LDHH+NLRP++LYP SPL+ NPG IDFV
Sbjct 61 DAILLGAIGAPGEVPPGVLERGLLLKMRFALDHHVNLRPSKLYPTATSPLA-NPGDIDFV 119
Query 119 VVREGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVHK 178
VVREGTEG Y GNGG +R GTP+E+A+EVS NT +GV RVV DAFERA+ R+KHLTLVHK
Sbjct 120 VVREGTEGLYCGNGGTLREGTPHEIASEVSQNTRYGVERVVRDAFERAQNRKKHLTLVHK 179
Query 179 TNVLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIIT 238
TNVL AGGLW RTV+E+ YP+V V Y H+DAATI+M+TDP R+DVIVTDNLFGDI+T
Sbjct 180 TNVLVNAGGLWQRTVNEIATEYPEVTVDYNHIDAATIYMVTDPSRYDVIVTDNLFGDILT 239
Query 239 DLAAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHL 298
DLA AV GGIGLAASGNIDAT NPSMFEPVHGSAPDIAGQGIADPTAAI+S A+LL H+
Sbjct 240 DLAGAVTGGIGLAASGNIDATGVNPSMFEPVHGSAPDIAGQGIADPTAAILSAAMLLRHV 299
Query 299 GEHDAAARVDRAVEAHLATRGSERLATSDVGERIAAAL 336
G+ A R++ AV +A R + + T +VG+RI AAL
Sbjct 300 GDESNAQRIEAAVTYDVAERPAGPVKTVEVGDRIVAAL 337
>gi|302558207|ref|ZP_07310549.1| 3-isopropylmalate dehydrogenase [Streptomyces griseoflavus Tu4000]
gi|302475825|gb|EFL38918.1| 3-isopropylmalate dehydrogenase [Streptomyces griseoflavus Tu4000]
Length=347
Score = 456 bits (1172), Expect = 3e-126, Method: Compositional matrix adjust.
Identities = 235/339 (70%), Positives = 271/339 (80%), Gaps = 5/339 (1%)
Query 1 MKLAIIAGDGIGPEVTAEAVKVLDAVVP---GVQKTSYDLGARRFHATGEVLPDSVVAEL 57
+ LA+I GDGIG EV AE +KVL AV+P ++ YD GARR+HATGE L D+ + EL
Sbjct 5 LNLAVIPGDGIGQEVVAEGLKVLSAVLPQDVKLETKEYDFGARRYHATGETLTDADLDEL 64
Query 58 RNHDAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDF 117
+ HDAILLGAIGDPSVPSGVLERG LL+LRF DHH+NLRP++L PGVA+PL+G P IDF
Sbjct 65 KRHDAILLGAIGDPSVPSGVLERGFLLKLRFAFDHHVNLRPSKLLPGVATPLAGEPQIDF 124
Query 118 VVVREGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRR-RKHLTLV 176
VVVREGTEGPYTGNGG IR GTP+EVATEVSVNTAFGV RVV DAF RA+ R RK LTLV
Sbjct 125 VVVREGTEGPYTGNGGTIRKGTPHEVATEVSVNTAFGVERVVRDAFARAQARPRKKLTLV 184
Query 177 HKTNVLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDI 236
HK NVLTFAG LW ++V E YP+V Y HVDAATI+++TDP RFDVIVTDNLFGDI
Sbjct 185 HKNNVLTFAGHLWTNVFNKVAEEYPEVTTDYIHVDAATIYLVTDPARFDVIVTDNLFGDI 244
Query 237 ITDLAAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLS 296
ITDLAAAV GGIG+AASGNI+ R PSMFEPVHGSAPDIAGQG ADP+A ++SVALLL
Sbjct 245 ITDLAAAVSGGIGVAASGNINPGREFPSMFEPVHGSAPDIAGQGKADPSATVLSVALLLR 304
Query 297 HLGEHDAAARVDRAVEAHLATRGS-ERLATSDVGERIAA 334
HLG AAR++ AV A LA RG +TS++G+ +AA
Sbjct 305 HLGHDAEAARIEDAVSADLAERGGLPARSTSEIGDALAA 343
>gi|229819911|ref|YP_002881437.1| 3-isopropylmalate dehydrogenase [Beutenbergia cavernae DSM 12333]
gi|259494339|sp|C5C2I9.1|LEU3_BEUC1 RecName: Full=3-isopropylmalate dehydrogenase; AltName: Full=3-IPM-DH;
AltName: Full=Beta-IPM dehydrogenase; Short=IMDH
gi|229565824|gb|ACQ79675.1| 3-isopropylmalate dehydrogenase [Beutenbergia cavernae DSM 12333]
Length=347
Score = 454 bits (1168), Expect = 8e-126, Method: Compositional matrix adjust.
Identities = 236/339 (70%), Positives = 273/339 (81%), Gaps = 5/339 (1%)
Query 1 MKLAIIAGDGIGPEVTAEAVKVLDAVVPG----VQKTSYDLGARRFHATGEVLPDSVVAE 56
+ LA++AGDGIGPEV AE +KVLDA + G V+ T+YDLGA R+HATGE L D +A
Sbjct 5 IDLAVVAGDGIGPEVVAEGLKVLDAALAGTDVTVRTTAYDLGAARWHATGETLTDEDLAA 64
Query 57 LRNHDAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGID 116
L HDAILLGAIGDP VPSGVLERGLLL+LRF DH++NLRP+RLYPGVA+PL+ +D
Sbjct 65 LAQHDAILLGAIGDPGVPSGVLERGLLLKLRFAFDHYVNLRPSRLYPGVATPLAKGGDVD 124
Query 117 FVVVREGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRR-RKHLTL 175
FVVVREGTEGPY GNGGAIRVGTP+E+A EVSVNTAFGV RVV DAF RA R RK LTL
Sbjct 125 FVVVREGTEGPYVGNGGAIRVGTPHEIANEVSVNTAFGVERVVRDAFARADARPRKKLTL 184
Query 176 VHKTNVLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGD 235
VHK NVL AG LW RTV+ VG +PDV V Y HVDAATI ++TDP RFDV+VTDNLFGD
Sbjct 185 VHKHNVLVHAGHLWRRTVEAVGAEFPDVAVDYLHVDAATIFLVTDPARFDVVVTDNLFGD 244
Query 236 IITDLAAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLL 295
I+TDLAAA+ GGIGLAASGNI+ RA PSMFEPVHGSAPDIAGQG ADPTA ++SVALLL
Sbjct 245 ILTDLAAAITGGIGLAASGNINPDRAFPSMFEPVHGSAPDIAGQGKADPTATVLSVALLL 304
Query 296 SHLGEHDAAARVDRAVEAHLATRGSERLATSDVGERIAA 334
HLG + AAR+ AVE+ + RGS +T++VG+ +AA
Sbjct 305 EHLGLTEQAARITAAVESDIVERGSAVRSTAEVGDALAA 343
>gi|227501756|ref|ZP_03931805.1| 3-isopropylmalate dehydrogenase [Corynebacterium accolens ATCC
49725]
gi|227077781|gb|EEI15744.1| 3-isopropylmalate dehydrogenase [Corynebacterium accolens ATCC
49725]
Length=339
Score = 452 bits (1162), Expect = 4e-125, Method: Compositional matrix adjust.
Identities = 233/338 (69%), Positives = 270/338 (80%), Gaps = 3/338 (0%)
Query 1 MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH 60
MKLA+I GDGIGPEVTAEA+KVL AV ++ T YDLGARR+ GE+L D+ +A LR H
Sbjct 1 MKLAVIGGDGIGPEVTAEALKVLRAVRSDIETTDYDLGARRYLRNGELLTDADLASLREH 60
Query 61 DAILLGAIGDP-SVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPG-IDFV 118
DAILLGAIG P VP GVLERGLLL++RF LDHH+NLRP+ LYP SPL+ NPG IDFV
Sbjct 61 DAILLGAIGAPGEVPPGVLERGLLLKMRFALDHHVNLRPSILYPTAHSPLA-NPGEIDFV 119
Query 119 VVREGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVHK 178
VVREGTEG Y GNGG +R GTP+EVA+EVS NT FGV RVV DAF RA +RR HLTLVHK
Sbjct 120 VVREGTEGLYCGNGGTLREGTPHEVASEVSQNTRFGVERVVRDAFARASQRRNHLTLVHK 179
Query 179 TNVLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIIT 238
TNVL AG LW RTV+EV YP VEV Y H+DAATI+M+TDP R+DVIVTDNLFGDI+T
Sbjct 180 TNVLVNAGDLWHRTVEEVSAEYPQVEVDYNHIDAATIYMVTDPARYDVIVTDNLFGDILT 239
Query 239 DLAAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHL 298
DLA A+ GGIGLAASGNIDA+ NPSMFEPVHGSAPDIAGQGIADPTAAI+S A+LL L
Sbjct 240 DLAGAITGGIGLAASGNIDASGKNPSMFEPVHGSAPDIAGQGIADPTAAILSAAMLLRQL 299
Query 299 GEHDAAARVDRAVEAHLATRGSERLATSDVGERIAAAL 336
G+ A ++++AV +A RG + T +VG+RIA +L
Sbjct 300 GDEGNAQKIEKAVAEDIAKRGDAPIKTVEVGDRIAGSL 337
>gi|302524969|ref|ZP_07277311.1| tartrate dehydrogenase [Streptomyces sp. AA4]
gi|302433864|gb|EFL05680.1| tartrate dehydrogenase [Streptomyces sp. AA4]
Length=346
Score = 451 bits (1161), Expect = 6e-125, Method: Compositional matrix adjust.
Identities = 245/336 (73%), Positives = 281/336 (84%), Gaps = 2/336 (0%)
Query 1 MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH 60
M+LA+I GDGIGPEV +EA+KVL V P + T+YDLGA R+HATGE+LP+SV+ ELR H
Sbjct 1 MRLAVIPGDGIGPEVVSEALKVLGEVAPAAEITNYDLGASRWHATGELLPESVLGELRQH 60
Query 61 DAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDFVVV 120
DAILLGA+GDP+VPSG+LERGLLLRLRFELDHH+NLRPARLYPGV PL+ +D VVV
Sbjct 61 DAILLGAVGDPTVPSGILERGLLLRLRFELDHHVNLRPARLYPGVRGPLADAGDVDMVVV 120
Query 121 REGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRR-RKHLTLVHKT 179
REGTEGPY GNGG +R T +E+ATEVSVNTAFGVRRVVADAF RA R RKHLTLVHKT
Sbjct 121 REGTEGPYAGNGGLLRKDTEHEIATEVSVNTAFGVRRVVADAFNRAEERPRKHLTLVHKT 180
Query 180 NVLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITD 239
NVL AG LW R V+EV +PDV VAY HVDAATIH++TDP RFDVIVTDNLFGDIITD
Sbjct 181 NVLEHAGSLWSRIVEEVSLEHPDVTVAYSHVDAATIHLVTDPSRFDVIVTDNLFGDIITD 240
Query 240 LAAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHLG 299
LAAAV GGIGLAASGN+D TR NPSMFEPVHGSAPDIAGQG+ADPTAA++SV+LLL HLG
Sbjct 241 LAAAVTGGIGLAASGNLDITRRNPSMFEPVHGSAPDIAGQGLADPTAAVLSVSLLLDHLG 300
Query 300 EHDAAARVDRAVEAHLATR-GSERLATSDVGERIAA 334
+ +AA R++ +V LATR S AT +G+R+AA
Sbjct 301 QKEAARRIEASVAFDLATRDQSSPGATQAIGDRLAA 336
>gi|255324582|ref|ZP_05365699.1| 3-isopropylmalate dehydrogenase [Corynebacterium tuberculostearicum
SK141]
gi|255298488|gb|EET77788.1| 3-isopropylmalate dehydrogenase [Corynebacterium tuberculostearicum
SK141]
Length=339
Score = 451 bits (1161), Expect = 6e-125, Method: Compositional matrix adjust.
Identities = 232/337 (69%), Positives = 269/337 (80%), Gaps = 1/337 (0%)
Query 1 MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNH 60
MKLA+I GDGIGPEVTAEA+KVL AV ++ T YDLGARR+ GE+L D+ + LR H
Sbjct 1 MKLAVIGGDGIGPEVTAEALKVLRAVRSDIEVTEYDLGARRYLRNGELLTDADLKSLREH 60
Query 61 DAILLGAIGDP-SVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDFVV 119
DAILLGAIG P VP GVLERGLLL++RF LDHH+NLRP+RLYP +SPL+ IDFVV
Sbjct 61 DAILLGAIGAPGEVPPGVLERGLLLKMRFALDHHVNLRPSRLYPTASSPLAEPGDIDFVV 120
Query 120 VREGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVHKT 179
VREGTEG Y GNGG +R GT +EVA+EVS NT FGV RVV DAF RA +RRKHLTLVHK
Sbjct 121 VREGTEGLYCGNGGTLREGTEHEVASEVSQNTRFGVERVVRDAFARAAQRRKHLTLVHKK 180
Query 180 NVLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITD 239
NVL AGGLW RTV+EV +P+V V YQH+DAATI+M+TDP R+DVIVTDNLFGDI+TD
Sbjct 181 NVLVNAGGLWQRTVNEVAAEFPEVRVDYQHIDAATIYMVTDPARYDVIVTDNLFGDILTD 240
Query 240 LAAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHLG 299
LA AV GGIGLAASGNIDA+ ANPSMFEPVHGSAPDIAG+GIADPTAAI+S A+LL H+G
Sbjct 241 LAGAVTGGIGLAASGNIDASGANPSMFEPVHGSAPDIAGKGIADPTAAILSAAMLLRHVG 300
Query 300 EHDAAARVDRAVEAHLATRGSERLATSDVGERIAAAL 336
+ A R++ AV +A RG L T +VG+RIA L
Sbjct 301 DESNAQRIEDAVAQDVAHRGDGPLKTVEVGDRIAQLL 337
Lambda K H
0.319 0.137 0.398
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 605194074128
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
Posted date: Sep 5, 2011 4:36 AM
Number of letters in database: 5,219,829,388
Number of sequences in database: 15,229,318
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40