BLASTP 2.2.25+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.



Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
           15,229,318 sequences; 5,219,829,388 total letters



Query= Rv2998A

Length=67
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

gi|31794175|ref|NP_856668.1|  hypothetical protein Mb3023c [Mycob...   133    9e-30
gi|340627988|ref|YP_004746440.1|  hypothetical protein MCAN_30211...   124    3e-27
gi|284041763|ref|YP_003392103.1|  integral membrane sensor signal...  89.7    1e-16
gi|170783569|ref|YP_001740086.1|  signal transduction histidine k...  82.8    2e-14
gi|345012351|ref|YP_004814705.1|  integral membrane sensor signal...  78.6    3e-13
gi|312197828|ref|YP_004017889.1|  integral membrane sensor signal...  77.4    7e-13
gi|288918431|ref|ZP_06412783.1|  histidine kinase [Frankia sp. EU...  73.9    6e-12
gi|345013722|ref|YP_004816076.1|  integral membrane sensor signal...  73.6    9e-12
gi|156742563|ref|YP_001432692.1|  integral membrane sensor signal...  72.8    1e-11
gi|219850343|ref|YP_002464776.1|  histidine kinase [Chloroflexus ...  72.8    1e-11
gi|345009062|ref|YP_004811416.1|  integral membrane sensor signal...  72.8    2e-11
gi|146300628|ref|YP_001195219.1|  integral membrane sensor signal...  72.0    3e-11
gi|336177575|ref|YP_004582950.1|  integral membrane sensor signal...  71.2    4e-11
gi|298247404|ref|ZP_06971209.1|  integral membrane sensor signal ...  70.5    8e-11
gi|158315648|ref|YP_001508156.1|  integral membrane sensor signal...  70.1    1e-10
gi|226228543|ref|YP_002762649.1|  two-component histidine kinase ...  69.7    1e-10
gi|312197789|ref|YP_004017850.1|  integral membrane sensor signal...  69.7    1e-10
gi|227539980|ref|ZP_03970029.1|  two-component system sensor hist...  69.3    2e-10
gi|300771737|ref|ZP_07081611.1|  conserved hypothetical protein [...  69.3    2e-10
gi|229489858|ref|ZP_04383714.1|  sensor kinase, two-component sys...  68.9    2e-10
gi|126663768|ref|ZP_01734764.1|  periplasmic sensor signal transd...  68.2    4e-10
gi|302870966|ref|YP_003839602.1|  integral membrane sensor signal...  68.2    4e-10
gi|110597759|ref|ZP_01386043.1|  ATP-binding region, ATPase-like:...  67.8    5e-10
gi|111025332|ref|YP_707752.1|  sensor histidine kinase [Rhodococc...  67.4    6e-10
gi|189346809|ref|YP_001943338.1|  integral membrane sensor signal...  67.0    9e-10
gi|312195394|ref|YP_004015455.1|  integral membrane sensor signal...  67.0    9e-10
gi|111020129|ref|YP_703101.1|  sensor kinase, two-component syste...  66.6    1e-09
gi|298248012|ref|ZP_06971817.1|  integral membrane sensor signal ...  66.6    1e-09
gi|159037189|ref|YP_001536442.1|  histidine kinase [Salinispora a...  66.6    1e-09
gi|222528318|ref|YP_002572200.1|  histidine kinase [Caldicellulos...  66.2    1e-09
gi|291435673|ref|ZP_06575063.1|  NlmB [Streptomyces ghanaensis AT...  66.2    2e-09
gi|229494403|ref|ZP_04388166.1|  sensor kinase, two-component sys...  65.9    2e-09
gi|226304508|ref|YP_002764466.1|  two-component histidine kinase ...  65.9    2e-09
gi|269128940|ref|YP_003302310.1|  histidine kinase [Thermomonospo...  65.9    2e-09
gi|300790442|ref|YP_003770733.1|  two-component system sensor kin...  65.5    2e-09
gi|307298685|ref|ZP_07578488.1|  integral membrane sensor signal ...  65.5    3e-09
gi|167969025|ref|ZP_02551302.1|  putative two component sensor ki...  65.1    3e-09
gi|326383366|ref|ZP_08205053.1|  ATP-binding region ATPase domain...  65.1    3e-09
gi|15607741|ref|NP_215115.1|  two component sensor kinase [Mycoba...  65.1    3e-09
gi|78187075|ref|YP_375118.1|  periplasmic sensor signal transduct...  65.1    3e-09
gi|271961704|ref|YP_003335900.1|  signal transduction histidine k...  65.1    3e-09
gi|116662228|ref|YP_829283.1|  periplasmic sensor signal transduc...  65.1    3e-09
gi|289568535|ref|ZP_06448762.1|  two component system sensor kina...  65.1    4e-09
gi|345010994|ref|YP_004813348.1|  integral membrane sensor signal...  65.1    4e-09
gi|226349418|ref|YP_002776532.1|  putative two-component histidin...  64.7    4e-09
gi|29826612|ref|NP_821246.1|  two-component system sensor kinase ...  64.7    4e-09
gi|297154562|gb|ADI04274.1|  two-component system sensor kinase [...  64.7    4e-09
gi|297163406|gb|ADI13118.1|  two-component system sensor kinase [...  64.7    4e-09
gi|329941811|ref|ZP_08291076.1|  putative two-component system se...  64.7    5e-09
gi|194336100|ref|YP_002017894.1|  integral membrane sensor signal...  64.3    6e-09


>gi|31794175|ref|NP_856668.1| hypothetical protein Mb3023c [Mycobacterium bovis AF2122/97]
 gi|57117043|ref|YP_177682.1| hypothetical protein Rv2998A [Mycobacterium tuberculosis H37Rv]
 gi|121638880|ref|YP_979104.1| hypothetical protein BCG_3020c [Mycobacterium bovis BCG str. 
Pasteur 1173P2]
 36 more sequence titles
 
gi|167967835|ref|ZP_02550112.1| hypothetical protein MtubH3_07302 [Mycobacterium tuberculosis 
H37Ra]
 gi|224991372|ref|YP_002646061.1| hypothetical protein JTY_3015 [Mycobacterium bovis BCG str. Tokyo 
172]
 gi|253797907|ref|YP_003030908.1| hypothetical protein TBMG_04006 [Mycobacterium tuberculosis KZN 
1435]
 gi|254552077|ref|ZP_05142524.1| hypothetical protein Mtube_16737 [Mycobacterium tuberculosis 
'98-R604 INH-RIF-EM']
 gi|289444564|ref|ZP_06434308.1| conserved hypothetical protein [Mycobacterium tuberculosis T46]
 gi|289448672|ref|ZP_06438416.1| conserved hypothetical protein [Mycobacterium tuberculosis CPHL_A]
 gi|289575706|ref|ZP_06455933.1| conserved hypothetical protein [Mycobacterium tuberculosis K85]
 gi|289746804|ref|ZP_06506182.1| conserved hypothetical protein [Mycobacterium tuberculosis 02_1987]
 gi|289751677|ref|ZP_06511055.1| conserved hypothetical protein [Mycobacterium tuberculosis T92]
 gi|289759125|ref|ZP_06518503.1| conserved hypothetical protein [Mycobacterium tuberculosis T85]
 gi|289763179|ref|ZP_06522557.1| conserved hypothetical protein [Mycobacterium tuberculosis GM 
1503]
 gi|294993913|ref|ZP_06799604.1| hypothetical protein Mtub2_05198 [Mycobacterium tuberculosis 
210]
 gi|297635624|ref|ZP_06953404.1| hypothetical protein MtubK4_15952 [Mycobacterium tuberculosis 
KZN 4207]
 gi|297732622|ref|ZP_06961740.1| hypothetical protein MtubKR_16112 [Mycobacterium tuberculosis 
KZN R506]
 gi|298526469|ref|ZP_07013878.1| conserved hypothetical protein [Mycobacterium tuberculosis 94_M4241A]
 gi|306973410|ref|ZP_07486071.1| hypothetical protein TMJG_01993 [Mycobacterium tuberculosis SUMu010]
 gi|313659954|ref|ZP_07816834.1| hypothetical protein MtubKV_16112 [Mycobacterium tuberculosis 
KZN V2475]
 gi|339633005|ref|YP_004724647.1| hypothetical protein MAF_30040 [Mycobacterium africanum GM041182]
 gi|31619770|emb|CAD96710.1| CONSERVED HYPOTHETICAL PROTEIN [Mycobacterium bovis AF2122/97]
 gi|41352772|emb|CAE55536.1| CONSERVED HYPOTHETICAL PROTEIN [Mycobacterium tuberculosis H37Rv]
 gi|121494528|emb|CAL73009.1| Conserved hypothetical protein [Mycobacterium bovis BCG str. 
Pasteur 1173P2]
 gi|224774487|dbj|BAH27293.1| hypothetical protein JTY_3015 [Mycobacterium bovis BCG str. Tokyo 
172]
 gi|253319410|gb|ACT24013.1| conserved hypothetical protein [Mycobacterium tuberculosis KZN 
1435]
 gi|289417483|gb|EFD14723.1| conserved hypothetical protein [Mycobacterium tuberculosis T46]
 gi|289421630|gb|EFD18831.1| conserved hypothetical protein [Mycobacterium tuberculosis CPHL_A]
 gi|289540137|gb|EFD44715.1| conserved hypothetical protein [Mycobacterium tuberculosis K85]
 gi|289687332|gb|EFD54820.1| conserved hypothetical protein [Mycobacterium tuberculosis 02_1987]
 gi|289692264|gb|EFD59693.1| conserved hypothetical protein [Mycobacterium tuberculosis T92]
 gi|289710685|gb|EFD74701.1| conserved hypothetical protein [Mycobacterium tuberculosis GM 
1503]
 gi|289714689|gb|EFD78701.1| conserved hypothetical protein [Mycobacterium tuberculosis T85]
 gi|298496263|gb|EFI31557.1| conserved hypothetical protein [Mycobacterium tuberculosis 94_M4241A]
 gi|308357210|gb|EFP46061.1| hypothetical protein TMJG_01993 [Mycobacterium tuberculosis SUMu010]
 gi|323718378|gb|EGB27552.1| hypothetical protein TMMG_03525 [Mycobacterium tuberculosis CDC1551A]
 gi|339332361|emb|CCC28074.1| conserved hypothetical protein [Mycobacterium africanum GM041182]
 gi|341602919|emb|CCC65597.1| conserved hypothetical protein [Mycobacterium bovis BCG str. 
Moreau RDJ]
 gi|344220833|gb|AEN01464.1| hypothetical protein MTCTRI2_3060 [Mycobacterium tuberculosis 
CTRI-2]
Length=67

 Score =  133 bits (334),  Expect = 9e-30, Method: Compositional matrix adjust.
 Identities = 66/67 (99%), Positives = 67/67 (100%), Gaps = 0/67 (0%)

Query  1   VERMRIRAAGISATDPHARLPLPLARDEIRYLGTTFNDLLQRLQDALERERQFVSDAGHE  60
           +ERMRIRAAGISATDPHARLPLPLARDEIRYLGTTFNDLLQRLQDALERERQFVSDAGHE
Sbjct  1   MERMRIRAAGISATDPHARLPLPLARDEIRYLGTTFNDLLQRLQDALERERQFVSDAGHE  60

Query  61  LRTPLAS  67
           LRTPLAS
Sbjct  61  LRTPLAS  67


>gi|340627988|ref|YP_004746440.1| hypothetical protein MCAN_30211 [Mycobacterium canettii CIPT 
140010059]
 gi|340006178|emb|CCC45352.1| conserved hypothetical protein [Mycobacterium canettii CIPT 140010059]
Length=68

 Score =  124 bits (312),  Expect = 3e-27, Method: Compositional matrix adjust.
 Identities = 62/66 (94%), Positives = 64/66 (97%), Gaps = 0/66 (0%)

Query  1   VERMRIRAAGISATDPHARLPLPLARDEIRYLGTTFNDLLQRLQDALERERQFVSDAGHE  60
           +ERMRIRAAGISATDPHARLPLPLARDEIRYLGT FN LLQRLQDALERERQFVSDAGHE
Sbjct  1   MERMRIRAAGISATDPHARLPLPLARDEIRYLGTRFNYLLQRLQDALERERQFVSDAGHE  60

Query  61  LRTPLA  66
           LRTPL+
Sbjct  61  LRTPLS  66


>gi|284041763|ref|YP_003392103.1| integral membrane sensor signal transduction histidine kinase 
[Conexibacter woesei DSM 14684]
 gi|283945984|gb|ADB48728.1| integral membrane sensor signal transduction histidine kinase 
[Conexibacter woesei DSM 14684]
Length=453

 Score = 89.7 bits (221),  Expect = 1e-16, Method: Compositional matrix adjust.
 Identities = 45/66 (69%), Positives = 52/66 (79%), Gaps = 0/66 (0%)

Query  1    VERMRIRAAGISATDPHARLPLPLARDEIRYLGTTFNDLLQRLQDALERERQFVSDAGHE  60
            VERMR RAA +S  DP ARLP+P ARDEIR LG T N +L RL  AL+RER+FV+DA HE
Sbjct  185  VERMRARAAAVSEEDPAARLPIPPARDEIRRLGETLNAMLDRLHGALDRERRFVADASHE  244

Query  61   LRTPLA  66
            LRTPL+
Sbjct  245  LRTPLS  250


>gi|170783569|ref|YP_001740086.1| signal transduction histidine kinase [Arthrobacter sp. Chr15]
 gi|150035077|gb|ABR67073.1| signal transduction histidine kinase [Arthrobacter sp. Chr15]
Length=454

 Score = 82.8 bits (203),  Expect = 2e-14, Method: Compositional matrix adjust.
 Identities = 40/64 (63%), Positives = 50/64 (79%), Gaps = 0/64 (0%)

Query  1    VERMRIRAAGISATDPHARLPLPLARDEIRYLGTTFNDLLQRLQDALERERQFVSDAGHE  60
            VERMR RAA I+A DP   LP+P ARDEI  LG TFN+L+ RL  +L+R+R+FV+DA H+
Sbjct  177  VERMRARAAAITADDPDQLLPVPPARDEISRLGATFNELINRLHASLDRQRRFVADASHD  236

Query  61   LRTP  64
            LRTP
Sbjct  237  LRTP  240


>gi|345012351|ref|YP_004814705.1| integral membrane sensor signal transduction histidine kinase 
[Streptomyces violaceusniger Tu 4113]
 gi|344038700|gb|AEM84425.1| integral membrane sensor signal transduction histidine kinase 
[Streptomyces violaceusniger Tu 4113]
Length=475

 Score = 78.6 bits (192),  Expect = 3e-13, Method: Compositional matrix adjust.
 Identities = 41/67 (62%), Positives = 51/67 (77%), Gaps = 0/67 (0%)

Query  1    VERMRIRAAGISATDPHARLPLPLARDEIRYLGTTFNDLLQRLQDALERERQFVSDAGHE  60
            VER+R +AA I+ATD H RL LP A DE+R LG T NDLL RL +A   +RQFV+DA HE
Sbjct  212  VERLRRQAAEITATDLHRRLDLPPAADEMRRLGATLNDLLARLDEATAHQRQFVADAAHE  271

Query  61   LRTPLAS  67
            LR+P+A+
Sbjct  272  LRSPVAA  278


>gi|312197828|ref|YP_004017889.1| integral membrane sensor signal transduction histidine kinase 
[Frankia sp. EuI1c]
 gi|311229164|gb|ADP82019.1| integral membrane sensor signal transduction histidine kinase 
[Frankia sp. EuI1c]
Length=479

 Score = 77.4 bits (189),  Expect = 7e-13, Method: Compositional matrix adjust.
 Identities = 39/67 (59%), Positives = 52/67 (78%), Gaps = 0/67 (0%)

Query  1    VERMRIRAAGISATDPHARLPLPLARDEIRYLGTTFNDLLQRLQDALERERQFVSDAGHE  60
            V+ +R +AA I+ATD H RL LPL+RDE+  L  TFNDLL RL+ A  R+R+FV++A HE
Sbjct  196  VDELRRQAAEITATDLHRRLDLPLSRDEVYNLAATFNDLLGRLEAATRRQREFVANAAHE  255

Query  61   LRTPLAS  67
            LR+P+AS
Sbjct  256  LRSPIAS  262


>gi|288918431|ref|ZP_06412783.1| histidine kinase [Frankia sp. EUN1f]
 gi|288350194|gb|EFC84419.1| histidine kinase [Frankia sp. EUN1f]
Length=509

 Score = 73.9 bits (180),  Expect = 6e-12, Method: Compositional matrix adjust.
 Identities = 39/67 (59%), Positives = 47/67 (71%), Gaps = 0/67 (0%)

Query  1    VERMRIRAAGISATDPHARLPLPLARDEIRYLGTTFNDLLQRLQDALERERQFVSDAGHE  60
            V+RMR + A IS +D  A L +P  RDEI  L TT NDLL+RL  A  R+R FV+DAGHE
Sbjct  202  VDRMRRQTAAISESDSAAELDVPATRDEIAALATTMNDLLRRLNAARARDRAFVADAGHE  261

Query  61   LRTPLAS  67
            LRTPL +
Sbjct  262  LRTPLTN  268


>gi|345013722|ref|YP_004816076.1| integral membrane sensor signal transduction histidine kinase 
[Streptomyces violaceusniger Tu 4113]
 gi|344040071|gb|AEM85796.1| integral membrane sensor signal transduction histidine kinase 
[Streptomyces violaceusniger Tu 4113]
Length=483

 Score = 73.6 bits (179),  Expect = 9e-12, Method: Compositional matrix adjust.
 Identities = 37/67 (56%), Positives = 49/67 (74%), Gaps = 0/67 (0%)

Query  1    VERMRIRAAGISATDPHARLPLPLARDEIRYLGTTFNDLLQRLQDALERERQFVSDAGHE  60
            VE +R +AA I+ATD H RL LP  +DE++ LG T ND+L RL DA   +R+FV+DA HE
Sbjct  207  VETLRRQAADITATDLHRRLDLPACQDEVQALGVTLNDMLARLDDASVAQRRFVADAAHE  266

Query  61   LRTPLAS  67
            LR+PL +
Sbjct  267  LRSPLTA  273


>gi|156742563|ref|YP_001432692.1| integral membrane sensor signal transduction histidine kinase 
[Roseiflexus castenholzii DSM 13941]
 gi|156233891|gb|ABU58674.1| integral membrane sensor signal transduction histidine kinase 
[Roseiflexus castenholzii DSM 13941]
Length=469

 Score = 72.8 bits (177),  Expect = 1e-11, Method: Compositional matrix adjust.
 Identities = 36/60 (60%), Positives = 43/60 (72%), Gaps = 0/60 (0%)

Query  8    AAGISATDPHARLPLPLARDEIRYLGTTFNDLLQRLQDALERERQFVSDAGHELRTPLAS  67
            A  ISATD HAR+ LP   DE+  L  TFN +L RL+DA  RERQF +DA HELRTP+A+
Sbjct  208  AQQISATDLHARITLPPTDDEVGRLAATFNSMLARLEDAFRRERQFTADASHELRTPVAA  267


>gi|219850343|ref|YP_002464776.1| histidine kinase [Chloroflexus aggregans DSM 9485]
 gi|219544602|gb|ACL26340.1| histidine kinase [Chloroflexus aggregans DSM 9485]
Length=469

 Score = 72.8 bits (177),  Expect = 1e-11, Method: Compositional matrix adjust.
 Identities = 36/60 (60%), Positives = 43/60 (72%), Gaps = 0/60 (0%)

Query  8    AAGISATDPHARLPLPLARDEIRYLGTTFNDLLQRLQDALERERQFVSDAGHELRTPLAS  67
            A  ISATD HAR+ LP   DE+  L  TFN +L RL+DA  RERQF +DA HELRTP+A+
Sbjct  208  AQQISATDLHARITLPPTDDEVGRLAATFNSMLARLEDAFRRERQFTADASHELRTPVAA  267


>gi|345009062|ref|YP_004811416.1| integral membrane sensor signal transduction histidine kinase 
[Streptomyces violaceusniger Tu 4113]
 gi|344035411|gb|AEM81136.1| integral membrane sensor signal transduction histidine kinase 
[Streptomyces violaceusniger Tu 4113]
Length=467

 Score = 72.8 bits (177),  Expect = 2e-11, Method: Compositional matrix adjust.
 Identities = 36/67 (54%), Positives = 48/67 (72%), Gaps = 0/67 (0%)

Query  1    VERMRIRAAGISATDPHARLPLPLARDEIRYLGTTFNDLLQRLQDALERERQFVSDAGHE  60
            VER+R  AA I+ +D H R+P P   DEI  L  T N +L+RL+D+  R+R+FV+DA HE
Sbjct  185  VERIRAEAAEITGSDLHRRIPGPTGDDEIGRLTGTLNSMLERLEDSATRQRRFVADASHE  244

Query  61   LRTPLAS  67
            LRTPLA+
Sbjct  245  LRTPLAA  251


>gi|146300628|ref|YP_001195219.1| integral membrane sensor signal transduction histidine kinase 
[Flavobacterium johnsoniae UW101]
 gi|146155046|gb|ABQ05900.1| integral membrane sensor signal transduction histidine kinase 
[Flavobacterium johnsoniae UW101]
Length=466

 Score = 72.0 bits (175),  Expect = 3e-11, Method: Composition-based stats.
 Identities = 31/55 (57%), Positives = 40/55 (73%), Gaps = 0/55 (0%)

Query  11   ISATDPHARLPLPLARDEIRYLGTTFNDLLQRLQDALERERQFVSDAGHELRTPL  65
            I+  +   R+PLP  RDE+  L  T N+LL R++DA+ERE+QF SDA HELRTPL
Sbjct  201  ITKDNLKTRIPLPKTRDELYTLSKTINNLLNRIEDAIEREKQFTSDASHELRTPL  255


>gi|336177575|ref|YP_004582950.1| integral membrane sensor signal transduction histidine kinase 
[Frankia symbiont of Datisca glomerata]
 gi|334858555|gb|AEH09029.1| integral membrane sensor signal transduction histidine kinase 
[Frankia symbiont of Datisca glomerata]
Length=533

 Score = 71.2 bits (173),  Expect = 4e-11, Method: Compositional matrix adjust.
 Identities = 38/65 (59%), Positives = 43/65 (67%), Gaps = 0/65 (0%)

Query  1    VERMRIRAAGISATDPHARLPLPLARDEIRYLGTTFNDLLQRLQDALERERQFVSDAGHE  60
            VERMR +AA +   D   RL +P  RDEI  L  T NDLL RL  A  R+R FV+DAGHE
Sbjct  180  VERMRRQAAAMGVADTGGRLEVPPTRDEIAALADTMNDLLDRLHAARARDRAFVADAGHE  239

Query  61   LRTPL  65
            LRTPL
Sbjct  240  LRTPL  244


>gi|298247404|ref|ZP_06971209.1| integral membrane sensor signal transduction histidine kinase 
[Ktedonobacter racemifer DSM 44963]
 gi|297550063|gb|EFH83929.1| integral membrane sensor signal transduction histidine kinase 
[Ktedonobacter racemifer DSM 44963]
Length=498

 Score = 70.5 bits (171),  Expect = 8e-11, Method: Compositional matrix adjust.
 Identities = 31/67 (47%), Positives = 48/67 (72%), Gaps = 0/67 (0%)

Query  1    VERMRIRAAGISATDPHARLPLPLARDEIRYLGTTFNDLLQRLQDALERERQFVSDAGHE  60
            + ++   A  I++ D   R+PLP ARDE+ +LG T N ++ RL+DA  R+++FV+DA HE
Sbjct  219  IHQLTSTARAINSGDLSQRVPLPRARDEVYFLGATLNAMIARLEDAFTRQKRFVADASHE  278

Query  61   LRTPLAS  67
            LRTP+A+
Sbjct  279  LRTPIAA  285


>gi|158315648|ref|YP_001508156.1| integral membrane sensor signal transduction histidine kinase 
[Frankia sp. EAN1pec]
 gi|158111053|gb|ABW13250.1| integral membrane sensor signal transduction histidine kinase 
[Frankia sp. EAN1pec]
Length=476

 Score = 70.1 bits (170),  Expect = 1e-10, Method: Compositional matrix adjust.
 Identities = 37/65 (57%), Positives = 45/65 (70%), Gaps = 0/65 (0%)

Query  1    VERMRIRAAGISATDPHARLPLPLARDEIRYLGTTFNDLLQRLQDALERERQFVSDAGHE  60
            V+RMR + A IS +D  A L +P  RDEI  L  T N+LL+RL  A  R+R FV+DAGHE
Sbjct  185  VDRMRRQTAAISESDSSAELDVPPTRDEIAALAATMNNLLRRLHAARARDRAFVADAGHE  244

Query  61   LRTPL  65
            LRTPL
Sbjct  245  LRTPL  249


>gi|226228543|ref|YP_002762649.1| two-component histidine kinase [Gemmatimonas aurantiaca T-27]
 gi|226091734|dbj|BAH40179.1| two-component histidine kinase [Gemmatimonas aurantiaca T-27]
Length=496

 Score = 69.7 bits (169),  Expect = 1e-10, Method: Compositional matrix adjust.
 Identities = 34/66 (52%), Positives = 47/66 (72%), Gaps = 0/66 (0%)

Query  1    VERMRIRAAGISATDPHARLPLPLARDEIRYLGTTFNDLLQRLQDALERERQFVSDAGHE  60
            V+ MR +A  I+A++ H RLP+P   DE+  L  TFN LL R++DA E+ R+F +DA HE
Sbjct  219  VDAMRAQAEQITASNLHERLPVPSTEDELSRLSRTFNALLDRVEDAFEQRRRFTADASHE  278

Query  61   LRTPLA  66
            LRTP+A
Sbjct  279  LRTPVA  284


>gi|312197789|ref|YP_004017850.1| integral membrane sensor signal transduction histidine kinase 
[Frankia sp. EuI1c]
 gi|311229125|gb|ADP81980.1| integral membrane sensor signal transduction histidine kinase 
[Frankia sp. EuI1c]
Length=466

 Score = 69.7 bits (169),  Expect = 1e-10, Method: Compositional matrix adjust.
 Identities = 37/67 (56%), Positives = 44/67 (66%), Gaps = 0/67 (0%)

Query  1    VERMRIRAAGISATDPHARLPLPLARDEIRYLGTTFNDLLQRLQDALERERQFVSDAGHE  60
            VERMR +AA +   D   RL +P  RDE+  L TT NDLL RL  A   +R FV+DAGHE
Sbjct  179  VERMRGQAAAMGVADLGGRLEIPPTRDELAALATTMNDLLDRLHVARAHDRAFVADAGHE  238

Query  61   LRTPLAS  67
            LRTPL +
Sbjct  239  LRTPLTN  245


>gi|227539980|ref|ZP_03970029.1| two-component system sensor histidine kinase [Sphingobacterium 
spiritivorum ATCC 33300]
 gi|227240258|gb|EEI90273.1| two-component system sensor histidine kinase [Sphingobacterium 
spiritivorum ATCC 33300]
Length=458

 Score = 69.3 bits (168),  Expect = 2e-10, Method: Composition-based stats.
 Identities = 34/67 (51%), Positives = 44/67 (66%), Gaps = 0/67 (0%)

Query  1    VERMRIRAAGISATDPHARLPLPLARDEIRYLGTTFNDLLQRLQDALERERQFVSDAGHE  60
            V  M  RA  IS T  H RL    A+DE+  L  TFNDLL RL+++ + ++QFVS+  HE
Sbjct  184  VREMTERARQISTTSLHMRLDTGHAKDELTELAETFNDLLNRLENSFDAQKQFVSNVAHE  243

Query  61   LRTPLAS  67
            LRTPLA+
Sbjct  244  LRTPLAA  250


>gi|300771737|ref|ZP_07081611.1| conserved hypothetical protein [Sphingobacterium spiritivorum 
ATCC 33861]
 gi|300761403|gb|EFK58225.1| conserved hypothetical protein [Sphingobacterium spiritivorum 
ATCC 33861]
Length=458

 Score = 69.3 bits (168),  Expect = 2e-10, Method: Composition-based stats.
 Identities = 34/67 (51%), Positives = 44/67 (66%), Gaps = 0/67 (0%)

Query  1    VERMRIRAAGISATDPHARLPLPLARDEIRYLGTTFNDLLQRLQDALERERQFVSDAGHE  60
            V  M  RA  IS T  H RL    A+DE+  L  TFNDLL RL+++ + ++QFVS+  HE
Sbjct  184  VREMTERARQISTTSLHMRLDTGHAKDELTELAETFNDLLNRLENSFDAQKQFVSNVAHE  243

Query  61   LRTPLAS  67
            LRTPLA+
Sbjct  244  LRTPLAA  250


>gi|229489858|ref|ZP_04383714.1| sensor kinase, two-component system [Rhodococcus erythropolis 
SK121]
 gi|229323208|gb|EEN88973.1| sensor kinase, two-component system [Rhodococcus erythropolis 
SK121]
Length=380

 Score = 68.9 bits (167),  Expect = 2e-10, Method: Compositional matrix adjust.
 Identities = 34/67 (51%), Positives = 47/67 (71%), Gaps = 0/67 (0%)

Query  1    VERMRIRAAGISATDPHARLPLPLARDEIRYLGTTFNDLLQRLQDALERERQFVSDAGHE  60
            VER+R R A IS +D   R+P+P +RDEI  L  T N +L+RLQ     +++FVSDA HE
Sbjct  107  VERIRTRVASISNSDLGERIPVPRSRDEIARLAVTMNRMLERLQAGQRAQQRFVSDASHE  166

Query  61   LRTPLAS  67
            LR+PL++
Sbjct  167  LRSPLST  173


>gi|126663768|ref|ZP_01734764.1| periplasmic sensor signal transduction histidine kinase [Flavobacteria 
bacterium BAL38]
 gi|126624351|gb|EAZ95043.1| periplasmic sensor signal transduction histidine kinase [Flavobacteria 
bacterium BAL38]
Length=462

 Score = 68.2 bits (165),  Expect = 4e-10, Method: Composition-based stats.
 Identities = 29/59 (50%), Positives = 42/59 (72%), Gaps = 0/59 (0%)

Query  8    AAGISATDPHARLPLPLARDEIRYLGTTFNDLLQRLQDALERERQFVSDAGHELRTPLA  66
            ++ I+  +   R+PLP  +DE+  L    N+LL R+++A+ERE+QF SDA HELRTPLA
Sbjct  196  SSKITKDNLQTRIPLPENKDELYVLSENINNLLNRVENAIEREKQFTSDASHELRTPLA  254


>gi|302870966|ref|YP_003839602.1| integral membrane sensor signal transduction histidine kinase 
[Caldicellulosiruptor obsidiansis OB47]
 gi|302573825|gb|ADL41616.1| integral membrane sensor signal transduction histidine kinase 
[Caldicellulosiruptor obsidiansis OB47]
Length=460

 Score = 68.2 bits (165),  Expect = 4e-10, Method: Composition-based stats.
 Identities = 32/67 (48%), Positives = 45/67 (68%), Gaps = 0/67 (0%)

Query  1    VERMRIRAAGISATDPHARLPLPLARDEIRYLGTTFNDLLQRLQDALERERQFVSDAGHE  60
            ++ +   A  I  TD   RL  P   DEI  L  TF+++L+RL++A +RER+F+SDA HE
Sbjct  187  IDDITTMARTIGHTDLSKRLNFPNTNDEIGRLALTFDEMLERLENAFKRERRFLSDASHE  246

Query  61   LRTPLAS  67
            LRTPLA+
Sbjct  247  LRTPLAT  253


>gi|110597759|ref|ZP_01386043.1| ATP-binding region, ATPase-like:Histidine kinase, HAMP region:Histidine 
kinase A-like [Chlorobium ferrooxidans DSM 13031]
 gi|110340666|gb|EAT59146.1| ATP-binding region, ATPase-like:Histidine kinase, HAMP region:Histidine 
kinase A-like [Chlorobium ferrooxidans DSM 13031]
Length=513

 Score = 67.8 bits (164),  Expect = 5e-10, Method: Composition-based stats.
 Identities = 32/67 (48%), Positives = 46/67 (69%), Gaps = 0/67 (0%)

Query  1    VERMRIRAAGISATDPHARLPLPLARDEIRYLGTTFNDLLQRLQDALERERQFVSDAGHE  60
            VE++   A  ++ ++ H R+ LP   DE+  L +T N LL R+QDA +RE+QF SDA HE
Sbjct  238  VEKIIETAEKMTQSNLHERIVLPYHHDELYRLSSTINALLDRMQDAFQREKQFTSDASHE  297

Query  61   LRTPLAS  67
            L+TPLA+
Sbjct  298  LKTPLAA  304


>gi|111025332|ref|YP_707752.1| sensor histidine kinase [Rhodococcus jostii RHA1]
 gi|110824311|gb|ABG99594.1| sensor histidine kinase [Rhodococcus jostii RHA1]
Length=469

 Score = 67.4 bits (163),  Expect = 6e-10, Method: Compositional matrix adjust.
 Identities = 34/67 (51%), Positives = 45/67 (68%), Gaps = 0/67 (0%)

Query  1    VERMRIRAAGISATDPHARLPLPLARDEIRYLGTTFNDLLQRLQDALERERQFVSDAGHE  60
            VE +R + A IS+TD   R+P+P  RDEI  L  T ND+L RL+     +R+FV DA HE
Sbjct  201  VEHIRTQVATISSTDLAERIPVPTPRDEIAALARTMNDMLTRLEAGHTAQRRFVGDASHE  260

Query  61   LRTPLAS  67
            LR+PLA+
Sbjct  261  LRSPLAT  267


>gi|189346809|ref|YP_001943338.1| integral membrane sensor signal transduction histidine kinase 
[Chlorobium limicola DSM 245]
 gi|189340956|gb|ACD90359.1| integral membrane sensor signal transduction histidine kinase 
[Chlorobium limicola DSM 245]
Length=495

 Score = 67.0 bits (162),  Expect = 9e-10, Method: Compositional matrix adjust.
 Identities = 34/67 (51%), Positives = 45/67 (68%), Gaps = 0/67 (0%)

Query  1    VERMRIRAAGISATDPHARLPLPLARDEIRYLGTTFNDLLQRLQDALERERQFVSDAGHE  60
            VE +   A  I+  +   R+PLP  +D++  L  T N LL+RLQDA +RE+QF SDA HE
Sbjct  225  VEEVIASAEKITRENLERRIPLPRNQDKLYRLSATINALLERLQDAFQREKQFTSDASHE  284

Query  61   LRTPLAS  67
            L+TPLAS
Sbjct  285  LKTPLAS  291


>gi|312195394|ref|YP_004015455.1| integral membrane sensor signal transduction histidine kinase 
[Frankia sp. EuI1c]
 gi|311226730|gb|ADP79585.1| integral membrane sensor signal transduction histidine kinase 
[Frankia sp. EuI1c]
Length=475

 Score = 67.0 bits (162),  Expect = 9e-10, Method: Compositional matrix adjust.
 Identities = 35/66 (54%), Positives = 45/66 (69%), Gaps = 0/66 (0%)

Query  1    VERMRIRAAGISATDPHARLPLPLARDEIRYLGTTFNDLLQRLQDALERERQFVSDAGHE  60
            V  +R   A I+ATD H R+P+P + DEI  L  T N  L RLQ A+ER ++FV+DA HE
Sbjct  177  VSAIRATFADITATDLHRRVPVPHSGDEIARLARTMNATLDRLQQAVERHKRFVADAAHE  236

Query  61   LRTPLA  66
            LR+PLA
Sbjct  237  LRSPLA  242


>gi|111020129|ref|YP_703101.1| sensor kinase, two-component system [Rhodococcus jostii RHA1]
 gi|110819659|gb|ABG94943.1| sensor kinase, two-component system [Rhodococcus jostii RHA1]
Length=472

 Score = 66.6 bits (161),  Expect = 1e-09, Method: Compositional matrix adjust.
 Identities = 34/67 (51%), Positives = 45/67 (68%), Gaps = 0/67 (0%)

Query  1    VERMRIRAAGISATDPHARLPLPLARDEIRYLGTTFNDLLQRLQDALERERQFVSDAGHE  60
            VE +R + A IS+TD   R+P+P  RDEI  L  T ND+L RL+     +R+FV DA HE
Sbjct  199  VEHIRTQVATISSTDLGERIPVPAPRDEIAALTRTMNDMLARLEAGHTAQRRFVGDASHE  258

Query  61   LRTPLAS  67
            LR+PLA+
Sbjct  259  LRSPLAT  265


>gi|298248012|ref|ZP_06971817.1| integral membrane sensor signal transduction histidine kinase 
[Ktedonobacter racemifer DSM 44963]
 gi|297550671|gb|EFH84537.1| integral membrane sensor signal transduction histidine kinase 
[Ktedonobacter racemifer DSM 44963]
Length=503

 Score = 66.6 bits (161),  Expect = 1e-09, Method: Compositional matrix adjust.
 Identities = 30/56 (54%), Positives = 42/56 (75%), Gaps = 0/56 (0%)

Query  11   ISATDPHARLPLPLARDEIRYLGTTFNDLLQRLQDALERERQFVSDAGHELRTPLA  66
            I A D H R+P+P ARDE+  L  TFN+++ RL+ A  ++R+FV+DA HELRTP+A
Sbjct  233  IEAGDLHRRVPIPRARDEVHELALTFNEMIGRLEQAFTQQRRFVADASHELRTPVA  288


>gi|159037189|ref|YP_001536442.1| histidine kinase [Salinispora arenicola CNS-205]
 gi|157916024|gb|ABV97451.1| histidine kinase [Salinispora arenicola CNS-205]
Length=442

 Score = 66.6 bits (161),  Expect = 1e-09, Method: Compositional matrix adjust.
 Identities = 34/67 (51%), Positives = 45/67 (68%), Gaps = 0/67 (0%)

Query  1    VERMRIRAAGISATDPHARLPLPLARDEIRYLGTTFNDLLQRLQDALERERQFVSDAGHE  60
            VE +R  A  I+  D   RLP+P +RDEI  L  T ND+L RL+ + +RER FV+DA HE
Sbjct  175  VEALRRGAEEITGRDGSGRLPVPASRDEIHRLAVTLNDMLDRLRASRDRERAFVADAAHE  234

Query  61   LRTPLAS  67
            LR+PL +
Sbjct  235  LRSPLTN  241


>gi|222528318|ref|YP_002572200.1| histidine kinase [Caldicellulosiruptor bescii DSM 6725]
 gi|222455165|gb|ACM59427.1| histidine kinase [Caldicellulosiruptor bescii DSM 6725]
Length=461

 Score = 66.2 bits (160),  Expect = 1e-09, Method: Composition-based stats.
 Identities = 31/60 (52%), Positives = 40/60 (67%), Gaps = 0/60 (0%)

Query  8    AAGISATDPHARLPLPLARDEIRYLGTTFNDLLQRLQDALERERQFVSDAGHELRTPLAS  67
            A  I  TD   RL  P   DEI  L  TF+++L RL++A +RER+F+SDA HELRTPL +
Sbjct  193  ARTIGHTDLSKRLNFPKVEDEIGRLAMTFDEMLDRLENAFKRERRFLSDASHELRTPLTT  252


>gi|291435673|ref|ZP_06575063.1| NlmB [Streptomyces ghanaensis ATCC 14672]
 gi|291338568|gb|EFE65524.1| NlmB [Streptomyces ghanaensis ATCC 14672]
Length=586

 Score = 66.2 bits (160),  Expect = 2e-09, Method: Compositional matrix adjust.
 Identities = 33/67 (50%), Positives = 44/67 (66%), Gaps = 0/67 (0%)

Query  1    VERMRIRAAGISATDPHARLPLPLARDEIRYLGTTFNDLLQRLQDALERERQFVSDAGHE  60
            VE +R   A ++A+DP  R+ +P    EI  L TT N  LQRL DA  R+R+FV+DA HE
Sbjct  316  VEAIRALTASVTASDPRERVTVPATGHEITALATTINTTLQRLDDAAARQRRFVADAAHE  375

Query  61   LRTPLAS  67
            LR+PL +
Sbjct  376  LRSPLTT  382


>gi|229494403|ref|ZP_04388166.1| sensor kinase, two-component system [Rhodococcus erythropolis 
SK121]
 gi|229318765|gb|EEN84623.1| sensor kinase, two-component system [Rhodococcus erythropolis 
SK121]
Length=447

 Score = 65.9 bits (159),  Expect = 2e-09, Method: Compositional matrix adjust.
 Identities = 33/67 (50%), Positives = 45/67 (68%), Gaps = 0/67 (0%)

Query  1    VERMRIRAAGISATDPHARLPLPLARDEIRYLGTTFNDLLQRLQDALERERQFVSDAGHE  60
            VER+R R A IS+     R+P+P   DEI  L TT ND+L RL +    +++FVSDA HE
Sbjct  180  VERIRARVASISSGRQGERVPVPSGNDEIARLATTMNDMLARLDEGALAQQRFVSDASHE  239

Query  61   LRTPLAS  67
            LR+PL++
Sbjct  240  LRSPLST  246


>gi|226304508|ref|YP_002764466.1| two-component histidine kinase [Rhodococcus erythropolis PR4]
 gi|226183623|dbj|BAH31727.1| putative two-component histidine kinase [Rhodococcus erythropolis 
PR4]
Length=484

 Score = 65.9 bits (159),  Expect = 2e-09, Method: Compositional matrix adjust.
 Identities = 33/67 (50%), Positives = 45/67 (68%), Gaps = 0/67 (0%)

Query  1    VERMRIRAAGISATDPHARLPLPLARDEIRYLGTTFNDLLQRLQDALERERQFVSDAGHE  60
            VER+R R A IS+     R+P+P   DEI  L TT ND+L RL +    +++FVSDA HE
Sbjct  212  VERIRARVASISSGRQGERVPVPSGNDEIARLATTMNDMLARLDEGALAQQRFVSDASHE  271

Query  61   LRTPLAS  67
            LR+PL++
Sbjct  272  LRSPLST  278


>gi|269128940|ref|YP_003302310.1| histidine kinase [Thermomonospora curvata DSM 43183]
 gi|268313898|gb|ACZ00273.1| histidine kinase [Thermomonospora curvata DSM 43183]
Length=454

 Score = 65.9 bits (159),  Expect = 2e-09, Method: Compositional matrix adjust.
 Identities = 35/67 (53%), Positives = 46/67 (69%), Gaps = 0/67 (0%)

Query  1    VERMRIRAAGISATDPHARLPLPLARDEIRYLGTTFNDLLQRLQDALERERQFVSDAGHE  60
            VE +R + + ISA+D   R+P P   DEI  L  T N+ L RL+ A+ER+RQF SDA HE
Sbjct  185  VEAIRAQLSEISASDLSRRVPQPPGEDEIAQLARTANETLDRLERAVERQRQFASDASHE  244

Query  61   LRTPLAS  67
            LRTP+A+
Sbjct  245  LRTPIAA  251


>gi|300790442|ref|YP_003770733.1| two-component system sensor kinase [Amycolatopsis mediterranei 
U32]
 gi|299799956|gb|ADJ50331.1| two-component system sensor kinase [Amycolatopsis mediterranei 
U32]
 gi|340532126|gb|AEK47331.1| two-component system sensor kinase [Amycolatopsis mediterranei 
S699]
Length=457

 Score = 65.5 bits (158),  Expect = 2e-09, Method: Compositional matrix adjust.
 Identities = 34/67 (51%), Positives = 45/67 (68%), Gaps = 0/67 (0%)

Query  1    VERMRIRAAGISATDPHARLPLPLARDEIRYLGTTFNDLLQRLQDALERERQFVSDAGHE  60
            VERMR   A IS  D  AR+PLP   DE++ L  T N++L RL  A   +R+FV+DA HE
Sbjct  190  VERMRRTVAEISTRDLAARVPLPPGGDEVQRLAVTLNEMLSRLASAQAAQRRFVADASHE  249

Query  61   LRTPLAS  67
            LR+PL++
Sbjct  250  LRSPLST  256


>gi|307298685|ref|ZP_07578488.1| integral membrane sensor signal transduction histidine kinase 
[Thermotogales bacterium MesG1.Ag.4.2]
 gi|306915850|gb|EFN46234.1| integral membrane sensor signal transduction histidine kinase 
[Thermotogales bacterium MesG1.Ag.4.2]
Length=460

 Score = 65.5 bits (158),  Expect = 3e-09, Method: Composition-based stats.
 Identities = 31/67 (47%), Positives = 48/67 (72%), Gaps = 0/67 (0%)

Query  1    VERMRIRAAGISATDPHARLPLPLARDEIRYLGTTFNDLLQRLQDALERERQFVSDAGHE  60
            VER+ + A  IS    + RL L L  DE+ +L +TF+ +L+RL+++++++RQF SDA HE
Sbjct  185  VERITLLAEEISVEKLNKRLNLTLPDDELGHLASTFDGMLERLEESVKKQRQFTSDAAHE  244

Query  61   LRTPLAS  67
            LRTPL +
Sbjct  245  LRTPLTA  251


>gi|167969025|ref|ZP_02551302.1| putative two component sensor kinase [Mycobacterium tuberculosis 
H37Ra]
 gi|254549558|ref|ZP_05140005.1| putative two component sensor kinase [Mycobacterium tuberculosis 
'98-R604 INH-RIF-EM']
 gi|294996115|ref|ZP_06801806.1| putative two component sensor kinase [Mycobacterium tuberculosis 
210]
 6 more sequence titles
 
gi|297633097|ref|ZP_06950877.1| putative two component sensor kinase [Mycobacterium tuberculosis 
KZN 4207]
 gi|297730075|ref|ZP_06959193.1| putative two component sensor kinase [Mycobacterium tuberculosis 
KZN R506]
 gi|313657402|ref|ZP_07814282.1| putative two component sensor kinase [Mycobacterium tuberculosis 
KZN V2475]
 gi|323720955|gb|EGB30020.1| two component system sensor kinase [Mycobacterium tuberculosis 
CDC1551A]
 gi|339293642|gb|AEJ45753.1| putative two component sensor kinase [Mycobacterium tuberculosis 
CCDC5079]
 gi|339297284|gb|AEJ49394.1| putative two component sensor kinase [Mycobacterium tuberculosis 
CCDC5180]
Length=176

 Score = 65.1 bits (157),  Expect = 3e-09, Method: Compositional matrix adjust.
 Identities = 37/65 (57%), Positives = 43/65 (67%), Gaps = 5/65 (7%)

Query  5    RIRAAGIS-ATDPH----ARLPLPLARDEIRYLGTTFNDLLQRLQDALERERQFVSDAGH  59
            RIRAA  +  T PH    A LP+P   DEI +L TT N +L RLQ AL  E+QFV+DA H
Sbjct  92   RIRAAAQTLTTTPHPDTDAPLPVPPTDDEIAWLATTLNTMLTRLQRALAHEQQFVADASH  151

Query  60   ELRTP  64
            ELRTP
Sbjct  152  ELRTP  156


>gi|326383366|ref|ZP_08205053.1| ATP-binding region ATPase domain-containing protein [Gordonia 
neofelifaecis NRRL B-59395]
 gi|326197772|gb|EGD54959.1| ATP-binding region ATPase domain-containing protein [Gordonia 
neofelifaecis NRRL B-59395]
Length=467

 Score = 65.1 bits (157),  Expect = 3e-09, Method: Compositional matrix adjust.
 Identities = 33/67 (50%), Positives = 43/67 (65%), Gaps = 0/67 (0%)

Query  1    VERMRIRAAGISATDPHARLPLPLARDEIRYLGTTFNDLLQRLQDALERERQFVSDAGHE  60
            VE +R R   IS  D H R+P+P  RDEI  L  T N++L RL++A  RE +FV DA HE
Sbjct  202  VEAIRRRVDEISVGDLHQRVPVPATRDEIATLAVTMNEMLDRLEEARARELRFVGDASHE  261

Query  61   LRTPLAS  67
            L +PL +
Sbjct  262  LNSPLTT  268


>gi|15607741|ref|NP_215115.1| two component sensor kinase [Mycobacterium tuberculosis H37Rv]
 gi|31791783|ref|NP_854276.1| two component sensor kinase [Mycobacterium bovis AF2122/97]
 gi|121636519|ref|YP_976742.1| putative two component sensor kinase (first part) [Mycobacterium 
bovis BCG str. Pasteur 1173P2]
 27 more sequence titles
 
gi|148660371|ref|YP_001281894.1| putative two component sensor kinase [Mycobacterium tuberculosis 
H37Ra]
 gi|224988991|ref|YP_002643678.1| putative two component sensor kinase [Mycobacterium bovis BCG 
str. Tokyo 172]
 gi|289441990|ref|ZP_06431734.1| two component system sensor kinase [Mycobacterium tuberculosis 
T46]
 gi|289446154|ref|ZP_06435898.1| two component system sensor kinase [Mycobacterium tuberculosis 
CPHL_A]
 gi|289749098|ref|ZP_06508476.1| two component system sensor kinase [Mycobacterium tuberculosis 
T92]
 gi|289752641|ref|ZP_06512019.1| two component sensor kinase [Mycobacterium tuberculosis EAS054]
 gi|289756680|ref|ZP_06516058.1| two component sensor kinase [Mycobacterium tuberculosis T85]
 gi|289760721|ref|ZP_06520099.1| two component sensor kinase [Mycobacterium tuberculosis GM 1503]
 gi|298524088|ref|ZP_07011497.1| two component sensor kinase [Mycobacterium tuberculosis 94_M4241A]
 gi|339630669|ref|YP_004722311.1| two component sensor kinase [Mycobacterium africanum GM041182]
 gi|81555761|sp|O07777.1|HK2_MYCTU RecName: Full=Sensor histidine kinase component HK2
 gi|2222757|emb|CAB09955.1| PROBABLE TWO COMPONENT SENSOR KINASE [FIRST PART] [Mycobacterium 
tuberculosis H37Rv]
 gi|31617370|emb|CAD93479.1| PROBABLE TWO COMPONENT SENSOR KINASE (FIRST PART) [Mycobacterium 
bovis AF2122/97]
 gi|121492166|emb|CAL70632.1| Probable two component sensor kinase (first part) [Mycobacterium 
bovis BCG str. Pasteur 1173P2]
 gi|148504523|gb|ABQ72332.1| putative two component sensor kinase [Mycobacterium tuberculosis 
H37Ra]
 gi|224772104|dbj|BAH24910.1| putative two component sensor kinase [Mycobacterium bovis BCG 
str. Tokyo 172]
 gi|289414909|gb|EFD12149.1| two component system sensor kinase [Mycobacterium tuberculosis 
T46]
 gi|289419112|gb|EFD16313.1| two component system sensor kinase [Mycobacterium tuberculosis 
CPHL_A]
 gi|289689685|gb|EFD57114.1| two component system sensor kinase [Mycobacterium tuberculosis 
T92]
 gi|289693228|gb|EFD60657.1| two component sensor kinase [Mycobacterium tuberculosis EAS054]
 gi|289708227|gb|EFD72243.1| two component sensor kinase [Mycobacterium tuberculosis GM 1503]
 gi|289712244|gb|EFD76256.1| two component sensor kinase [Mycobacterium tuberculosis T85]
 gi|298493882|gb|EFI29176.1| two component sensor kinase [Mycobacterium tuberculosis 94_M4241A]
 gi|326902433|gb|EGE49366.1| two component system sensor kinase [Mycobacterium tuberculosis 
W-148]
 gi|339330025|emb|CCC25680.1| putative two component sensor kinase [first part] [Mycobacterium 
africanum GM041182]
 gi|341600535|emb|CCC63205.1| probable two component sensor kinase (first part) [Mycobacterium 
bovis BCG str. Moreau RDJ]
 gi|344218423|gb|AEM99053.1| two component sensor kinase [Mycobacterium tuberculosis CTRI-2]
Length=156

 Score = 65.1 bits (157),  Expect = 3e-09, Method: Compositional matrix adjust.
 Identities = 37/65 (57%), Positives = 43/65 (67%), Gaps = 5/65 (7%)

Query  5    RIRAAGIS-ATDPH----ARLPLPLARDEIRYLGTTFNDLLQRLQDALERERQFVSDAGH  59
            RIRAA  +  T PH    A LP+P   DEI +L TT N +L RLQ AL  E+QFV+DA H
Sbjct  72   RIRAAAQTLTTTPHPDTDAPLPVPPTDDEIAWLATTLNTMLTRLQRALAHEQQFVADASH  131

Query  60   ELRTP  64
            ELRTP
Sbjct  132  ELRTP  136


>gi|78187075|ref|YP_375118.1| periplasmic sensor signal transduction histidine kinase [Chlorobium 
luteolum DSM 273]
 gi|78166977|gb|ABB24075.1| periplasmic sensor signal transduction histidine kinase [Chlorobium 
luteolum DSM 273]
Length=472

 Score = 65.1 bits (157),  Expect = 3e-09, Method: Compositional matrix adjust.
 Identities = 33/67 (50%), Positives = 43/67 (65%), Gaps = 0/67 (0%)

Query  1    VERMRIRAAGISATDPHARLPLPLARDEIRYLGTTFNDLLQRLQDALERERQFVSDAGHE  60
            VE   + A  I+      R+PLP  RDE+  L  TFN LL RLQ+A  RE+QF +DA HE
Sbjct  196  VEEAIMAAENITREHFERRIPLPANRDELYRLSATFNALLDRLQEAFNREKQFTADASHE  255

Query  61   LRTPLAS  67
            L+TPL++
Sbjct  256  LKTPLSA  262


>gi|271961704|ref|YP_003335900.1| signal transduction histidine kinase-like protein [Streptosporangium 
roseum DSM 43021]
 gi|270504879|gb|ACZ83157.1| Signal transduction histidine kinase-like protein [Streptosporangium 
roseum DSM 43021]
Length=472

 Score = 65.1 bits (157),  Expect = 3e-09, Method: Compositional matrix adjust.
 Identities = 33/66 (50%), Positives = 46/66 (70%), Gaps = 0/66 (0%)

Query  1    VERMRIRAAGISATDPHARLPLPLARDEIRYLGTTFNDLLQRLQDALERERQFVSDAGHE  60
            V  +R   A I+A+D H R+P+P +RDEI  L  T N  L RL+ A++R ++FV+DA HE
Sbjct  217  VSAIRTEMADITASDLHRRVPVPRSRDEIARLAETMNRTLDRLELAVDRHKRFVADAAHE  276

Query  61   LRTPLA  66
            LR+PLA
Sbjct  277  LRSPLA  282


>gi|116662228|ref|YP_829283.1| periplasmic sensor signal transduction histidine kinase [Arthrobacter 
sp. FB24]
 gi|116612980|gb|ABK05702.1| periplasmic sensor signal transduction histidine kinase [Arthrobacter 
sp. FB24]
Length=484

 Score = 65.1 bits (157),  Expect = 3e-09, Method: Compositional matrix adjust.
 Identities = 34/67 (51%), Positives = 47/67 (71%), Gaps = 0/67 (0%)

Query  1    VERMRIRAAGISATDPHARLPLPLARDEIRYLGTTFNDLLQRLQDALERERQFVSDAGHE  60
            VER+R + AGISA +   R+ +P   DEI+ L  T N +L RLQ + + +R+FVSDA HE
Sbjct  200  VERIRGQVAGISARNLDGRVDVPPTSDEIQALAETMNMMLGRLQASDQEQRRFVSDASHE  259

Query  61   LRTPLAS  67
            LR+PLA+
Sbjct  260  LRSPLAT  266


>gi|289568535|ref|ZP_06448762.1| two component system sensor kinase [Mycobacterium tuberculosis 
T17]
 gi|289542289|gb|EFD45937.1| two component system sensor kinase [Mycobacterium tuberculosis 
T17]
Length=175

 Score = 65.1 bits (157),  Expect = 4e-09, Method: Compositional matrix adjust.
 Identities = 37/65 (57%), Positives = 43/65 (67%), Gaps = 5/65 (7%)

Query  5    RIRAAGIS-ATDPH----ARLPLPLARDEIRYLGTTFNDLLQRLQDALERERQFVSDAGH  59
            RIRAA  +  T PH    A LP+P   DEI +L TT N +L RLQ AL  E+QFV+DA H
Sbjct  91   RIRAAAQTLTTTPHPDTDAPLPVPPTDDEIAWLATTLNTMLTRLQRALAHEQQFVADASH  150

Query  60   ELRTP  64
            ELRTP
Sbjct  151  ELRTP  155


>gi|345010994|ref|YP_004813348.1| integral membrane sensor signal transduction histidine kinase 
[Streptomyces violaceusniger Tu 4113]
 gi|344037343|gb|AEM83068.1| integral membrane sensor signal transduction histidine kinase 
[Streptomyces violaceusniger Tu 4113]
Length=507

 Score = 65.1 bits (157),  Expect = 4e-09, Method: Compositional matrix adjust.
 Identities = 31/67 (47%), Positives = 45/67 (68%), Gaps = 0/67 (0%)

Query  1    VERMRIRAAGISATDPHARLPLPLARDEIRYLGTTFNDLLQRLQDALERERQFVSDAGHE  60
            VE +R+  A ++A+DP  R+ +P    EI  L TT N  LQRL +A  ++R+FV+DA HE
Sbjct  221  VEAIRVLTASVTASDPRERVTVPATGHEITALATTINTTLQRLDNAAAQQRRFVADAAHE  280

Query  61   LRTPLAS  67
            LR+PL +
Sbjct  281  LRSPLTT  287


>gi|226349418|ref|YP_002776532.1| putative two-component histidine kinase [Rhodococcus opacus B4]
 gi|226245333|dbj|BAH55680.1| putative two-component histidine kinase [Rhodococcus opacus B4]
Length=478

 Score = 64.7 bits (156),  Expect = 4e-09, Method: Compositional matrix adjust.
 Identities = 30/67 (45%), Positives = 45/67 (68%), Gaps = 0/67 (0%)

Query  1    VERMRIRAAGISATDPHARLPLPLARDEIRYLGTTFNDLLQRLQDALERERQFVSDAGHE  60
            VE++R R A IS++D   R+P+P   DEI  L  T N +L R++     +R+FV+DA HE
Sbjct  196  VEKIRTRVAAISSSDLAERVPVPTQHDEIAALAETMNAMLSRIESGQHAQRRFVADASHE  255

Query  61   LRTPLAS  67
            LR+PL++
Sbjct  256  LRSPLST  262


>gi|29826612|ref|NP_821246.1| two-component system sensor kinase [Streptomyces avermitilis 
MA-4680]
 gi|29603708|dbj|BAC67781.1| putative two-component system sensor kinase [Streptomyces avermitilis 
MA-4680]
Length=551

 Score = 64.7 bits (156),  Expect = 4e-09, Method: Compositional matrix adjust.
 Identities = 32/67 (48%), Positives = 45/67 (68%), Gaps = 0/67 (0%)

Query  1    VERMRIRAAGISATDPHARLPLPLARDEIRYLGTTFNDLLQRLQDALERERQFVSDAGHE  60
            VE +R R A ++A DP  R+ +P   DE+  L  T N  LQRL++A   +R+FV+DA HE
Sbjct  256  VEAIRARTASVTAADPRERVEVPDTADEVAELALTINATLQRLEEAATAQRRFVADAAHE  315

Query  61   LRTPLAS  67
            LR+PLA+
Sbjct  316  LRSPLAT  322


>gi|297154562|gb|ADI04274.1| two-component system sensor kinase [Streptomyces bingchenggensis 
BCW-1]
Length=504

 Score = 64.7 bits (156),  Expect = 4e-09, Method: Compositional matrix adjust.
 Identities = 31/67 (47%), Positives = 45/67 (68%), Gaps = 0/67 (0%)

Query  1    VERMRIRAAGISATDPHARLPLPLARDEIRYLGTTFNDLLQRLQDALERERQFVSDAGHE  60
            VE +R+  A ++A+DP  R+ +P    EI  L TT N  LQRL +A  ++R+FV+DA HE
Sbjct  234  VEAIRVLTASVTASDPRERVTVPATGHEITALATTINTTLQRLDNAAAQQRRFVADAAHE  293

Query  61   LRTPLAS  67
            LR+PL +
Sbjct  294  LRSPLTT  300


>gi|297163406|gb|ADI13118.1| two-component system sensor kinase [Streptomyces bingchenggensis 
BCW-1]
Length=491

 Score = 64.7 bits (156),  Expect = 4e-09, Method: Compositional matrix adjust.
 Identities = 31/67 (47%), Positives = 44/67 (66%), Gaps = 0/67 (0%)

Query  1    VERMRIRAAGISATDPHARLPLPLARDEIRYLGTTFNDLLQRLQDALERERQFVSDAGHE  60
            VE +R+  A ++A+DP  R+ +P    EI  L TT N  LQRL +A   +R+FV+DA HE
Sbjct  221  VEAIRVLTASVTASDPRERVTVPATGHEITALATTINTTLQRLDNAAAEQRRFVADAAHE  280

Query  61   LRTPLAS  67
            LR+PL +
Sbjct  281  LRSPLTT  287


>gi|329941811|ref|ZP_08291076.1| putative two-component system sensor kinase [Streptomyces griseoaurantiacus 
M045]
 gi|329299528|gb|EGG43428.1| putative two-component system sensor kinase [Streptomyces griseoaurantiacus 
M045]
Length=488

 Score = 64.7 bits (156),  Expect = 5e-09, Method: Compositional matrix adjust.
 Identities = 31/67 (47%), Positives = 43/67 (65%), Gaps = 0/67 (0%)

Query  1    VERMRIRAAGISATDPHARLPLPLARDEIRYLGTTFNDLLQRLQDALERERQFVSDAGHE  60
            +E +R+  A ++  DP  R+ LP    EI  L TT N  LQRL DA  ++R+FV+DA HE
Sbjct  217  IEAIRVLTASVTPNDPRERITLPATGHEISALATTLNGTLQRLDDAAAQQRRFVADASHE  276

Query  61   LRTPLAS  67
            LR+PL +
Sbjct  277  LRSPLTT  283


>gi|194336100|ref|YP_002017894.1| integral membrane sensor signal transduction histidine kinase 
[Pelodictyon phaeoclathratiforme BU-1]
 gi|194308577|gb|ACF43277.1| integral membrane sensor signal transduction histidine kinase 
[Pelodictyon phaeoclathratiforme BU-1]
Length=500

 Score = 64.3 bits (155),  Expect = 6e-09, Method: Composition-based stats.
 Identities = 29/66 (44%), Positives = 43/66 (66%), Gaps = 0/66 (0%)

Query  1    VERMRIRAAGISATDPHARLPLPLARDEIRYLGTTFNDLLQRLQDALERERQFVSDAGHE  60
            +E++   A  ++ T+   R+PLP   DE+  L  T N L+ R+QDA +RE+ F +DA HE
Sbjct  226  IEKVIATAEKMTQTNLDHRIPLPYHHDELYRLSVTINALVTRMQDAFQREKHFTADASHE  285

Query  61   LRTPLA  66
            L+TPLA
Sbjct  286  LKTPLA  291



Lambda     K      H
   0.322    0.137    0.386 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Effective search space used: 129524807608


  Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
    Posted date:  Sep 5, 2011  4:36 AM
  Number of letters in database: 5,219,829,388
  Number of sequences in database:  15,229,318



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40