BLASTP 2.2.25+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.



Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
           15,229,318 sequences; 5,219,829,388 total letters



Query= Rv3018A

Length=28
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

gi|148662870|ref|YP_001284393.1|  PPE family protein [Mycobacteri...  51.6    3e-05
gi|289746825|ref|ZP_06506203.1|  PE family protein [Mycobacterium...  51.2    5e-05
gi|253797886|ref|YP_003030887.1|  hypothetical protein TBMG_04005...  50.8    6e-05
gi|254233095|ref|ZP_04926422.1|  PE family protein [Mycobacterium...  50.4    8e-05
gi|306804804|ref|ZP_07441472.1|  putative PE family protein [Myco...  50.4    9e-05
gi|167966626|ref|ZP_02548903.1|  PE family protein [Mycobacterium...  50.4    9e-05
gi|308369801|ref|ZP_07419129.2|  PE family protein [Mycobacterium...  50.1    1e-04
gi|308372403|ref|ZP_07428546.2|  putative PE family protein [Myco...  50.1    1e-04
gi|308406033|ref|ZP_07669494.1|  PPE family protein [Mycobacteriu...  50.1    1e-04
gi|308232317|ref|ZP_07664054.1|  PPE family protein [Mycobacteriu...  50.1    1e-04
gi|240171484|ref|ZP_04750143.1|  PE domain-containing protein [My...  40.0    0.11 
gi|15827194|ref|NP_301457.1|  PE-family protein [Mycobacterium le...  37.7    0.57 
gi|254821558|ref|ZP_05226559.1|  PE family protein [Mycobacterium...  35.4    2.7  
gi|212596236|gb|ACJ35562.1|  PE1 [Mycobacterium intracellulare AT...  35.4    2.7  
gi|148824209|ref|YP_001288963.1|  PE family protein [Mycobacteriu...  35.4    2.8  
gi|41406220|ref|NP_959056.1|  hypothetical protein MAP0122 [Mycob...  35.4    3.0  
gi|339633026|ref|YP_004724668.1|  PE family protein [Mycobacteriu...  35.0    3.8  
gi|342860175|ref|ZP_08716827.1|  PE family protein [Mycobacterium...  34.3    6.3  
gi|254773162|ref|ZP_05214678.1|  PE family protein [Mycobacterium...  33.9    9.3  


>gi|148662870|ref|YP_001284393.1| PPE family protein [Mycobacterium tuberculosis H37Ra]
 gi|289448693|ref|ZP_06438437.1| PE family protein [Mycobacterium tuberculosis CPHL_A]
 gi|289553191|ref|ZP_06442401.1| PE family protein [Mycobacterium tuberculosis KZN 605]
 gi|289575727|ref|ZP_06455954.1| PE-PGRS family protein [Mycobacterium tuberculosis K85]
 gi|148507022|gb|ABQ74831.1| PPE family protein [Mycobacterium tuberculosis H37Ra]
 gi|289421651|gb|EFD18852.1| PE family protein [Mycobacterium tuberculosis CPHL_A]
 gi|289437823|gb|EFD20316.1| PE family protein [Mycobacterium tuberculosis KZN 605]
 gi|289540158|gb|EFD44736.1| PE-PGRS family protein [Mycobacterium tuberculosis K85]
Length=94

 Score = 51.6 bits (122),  Expect = 3e-05, Method: Compositional matrix adjust.
 Identities = 28/28 (100%), Positives = 28/28 (100%), Gaps = 0/28 (0%)

Query  1   VTLSVVPEGLAAASAAVEALTARLAAAH  28
           VTLSVVPEGLAAASAAVEALTARLAAAH
Sbjct  67  VTLSVVPEGLAAASAAVEALTARLAAAH  94


>gi|289746825|ref|ZP_06506203.1| PE family protein [Mycobacterium tuberculosis 02_1987]
 gi|289687353|gb|EFD54841.1| PE family protein [Mycobacterium tuberculosis 02_1987]
 gi|328457663|gb|AEB03086.1| PE family protein [Mycobacterium tuberculosis KZN 4207]
Length=67

 Score = 51.2 bits (121),  Expect = 5e-05, Method: Compositional matrix adjust.
 Identities = 28/28 (100%), Positives = 28/28 (100%), Gaps = 0/28 (0%)

Query  1   VTLSVVPEGLAAASAAVEALTARLAAAH  28
           VTLSVVPEGLAAASAAVEALTARLAAAH
Sbjct  40  VTLSVVPEGLAAASAAVEALTARLAAAH  67


>gi|253797886|ref|YP_003030887.1| hypothetical protein TBMG_04005 [Mycobacterium tuberculosis KZN 
1435]
 gi|308373638|ref|ZP_07667618.1| hypothetical protein TMEG_04055 [Mycobacterium tuberculosis SUMu005]
 gi|253319389|gb|ACT23992.1| conserved hypothetical protein [Mycobacterium tuberculosis KZN 
1435]
 gi|308336871|gb|EFP25722.1| hypothetical protein TMEG_04055 [Mycobacterium tuberculosis SUMu005]
 gi|326904633|gb|EGE51566.1| hypothetical protein TBPG_02541 [Mycobacterium tuberculosis W-148]
Length=57

 Score = 50.8 bits (120),  Expect = 6e-05, Method: Compositional matrix adjust.
 Identities = 28/28 (100%), Positives = 28/28 (100%), Gaps = 0/28 (0%)

Query  1   VTLSVVPEGLAAASAAVEALTARLAAAH  28
           VTLSVVPEGLAAASAAVEALTARLAAAH
Sbjct  30  VTLSVVPEGLAAASAAVEALTARLAAAH  57


>gi|254233095|ref|ZP_04926422.1| PE family protein [Mycobacterium tuberculosis C]
 gi|124602154|gb|EAY61164.1| PE family protein [Mycobacterium tuberculosis C]
Length=48

 Score = 50.4 bits (119),  Expect = 8e-05, Method: Compositional matrix adjust.
 Identities = 28/28 (100%), Positives = 28/28 (100%), Gaps = 0/28 (0%)

Query  1   VTLSVVPEGLAAASAAVEALTARLAAAH  28
           VTLSVVPEGLAAASAAVEALTARLAAAH
Sbjct  21  VTLSVVPEGLAAASAAVEALTARLAAAH  48


>gi|306804804|ref|ZP_07441472.1| putative PE family protein [Mycobacterium tuberculosis SUMu008]
 gi|306808997|ref|ZP_07445665.1| putative PE family protein [Mycobacterium tuberculosis SUMu007]
 gi|308372321|ref|ZP_07667351.1| PE family protein [Mycobacterium tuberculosis SUMu004]
 6 more sequence titles
 
gi|308378167|ref|ZP_07668680.1| putative PE family protein [Mycobacterium tuberculosis SUMu009]
 gi|308333637|gb|EFP22488.1| PE family protein [Mycobacterium tuberculosis SUMu004]
 gi|308344710|gb|EFP33561.1| putative PE family protein [Mycobacterium tuberculosis SUMu007]
 gi|308348659|gb|EFP37510.1| putative PE family protein [Mycobacterium tuberculosis SUMu008]
 gi|308353386|gb|EFP42237.1| putative PE family protein [Mycobacterium tuberculosis SUMu009]
 gi|339295857|gb|AEJ47968.1| PE family protein [Mycobacterium tuberculosis CCDC5079]
Length=105

 Score = 50.4 bits (119),  Expect = 9e-05, Method: Compositional matrix adjust.
 Identities = 28/28 (100%), Positives = 28/28 (100%), Gaps = 0/28 (0%)

Query  1   VTLSVVPEGLAAASAAVEALTARLAAAH  28
           VTLSVVPEGLAAASAAVEALTARLAAAH
Sbjct  2   VTLSVVPEGLAAASAAVEALTARLAAAH  29


>gi|167966626|ref|ZP_02548903.1| PE family protein [Mycobacterium tuberculosis H37Ra]
Length=107

 Score = 50.4 bits (119),  Expect = 9e-05, Method: Compositional matrix adjust.
 Identities = 28/28 (100%), Positives = 28/28 (100%), Gaps = 0/28 (0%)

Query  1   VTLSVVPEGLAAASAAVEALTARLAAAH  28
           VTLSVVPEGLAAASAAVEALTARLAAAH
Sbjct  4   VTLSVVPEGLAAASAAVEALTARLAAAH  31


>gi|308369801|ref|ZP_07419129.2| PE family protein [Mycobacterium tuberculosis SUMu002]
 gi|308371210|ref|ZP_07424193.2| PE family protein [Mycobacterium tuberculosis SUMu003]
 gi|308373640|ref|ZP_07433147.2| putative PE family protein [Mycobacterium tuberculosis SUMu005]
 gi|308374703|ref|ZP_07437033.2| putative PE family protein [Mycobacterium tuberculosis SUMu006]
 gi|308326369|gb|EFP15220.1| PE family protein [Mycobacterium tuberculosis SUMu002]
 gi|308329490|gb|EFP18341.1| PE family protein [Mycobacterium tuberculosis SUMu003]
 gi|308336869|gb|EFP25720.1| putative PE family protein [Mycobacterium tuberculosis SUMu005]
 gi|308341019|gb|EFP29870.1| putative PE family protein [Mycobacterium tuberculosis SUMu006]
Length=104

 Score = 50.1 bits (118),  Expect = 1e-04, Method: Compositional matrix adjust.
 Identities = 28/28 (100%), Positives = 28/28 (100%), Gaps = 0/28 (0%)

Query  1   VTLSVVPEGLAAASAAVEALTARLAAAH  28
           VTLSVVPEGLAAASAAVEALTARLAAAH
Sbjct  10  VTLSVVPEGLAAASAAVEALTARLAAAH  37


>gi|308372403|ref|ZP_07428546.2| putative PE family protein [Mycobacterium tuberculosis SUMu004]
 gi|308333337|gb|EFP22188.1| putative PE family protein [Mycobacterium tuberculosis SUMu004]
Length=102

 Score = 50.1 bits (118),  Expect = 1e-04, Method: Compositional matrix adjust.
 Identities = 28/28 (100%), Positives = 28/28 (100%), Gaps = 0/28 (0%)

Query  1   VTLSVVPEGLAAASAAVEALTARLAAAH  28
           VTLSVVPEGLAAASAAVEALTARLAAAH
Sbjct  10  VTLSVVPEGLAAASAAVEALTARLAAAH  37


>gi|308406033|ref|ZP_07669494.1| PPE family protein [Mycobacterium tuberculosis SUMu012]
 gi|308364733|gb|EFP53584.1| PPE family protein [Mycobacterium tuberculosis SUMu012]
Length=31

 Score = 50.1 bits (118),  Expect = 1e-04, Method: Compositional matrix adjust.
 Identities = 28/28 (100%), Positives = 28/28 (100%), Gaps = 0/28 (0%)

Query  1   VTLSVVPEGLAAASAAVEALTARLAAAH  28
           VTLSVVPEGLAAASAAVEALTARLAAAH
Sbjct  4   VTLSVVPEGLAAASAAVEALTARLAAAH  31


>gi|308232317|ref|ZP_07664054.1| PPE family protein [Mycobacterium tuberculosis SUMu001]
 gi|308369799|ref|ZP_07666808.1| PPE family protein [Mycobacterium tuberculosis SUMu002]
 gi|308369933|ref|ZP_07419566.2| PPE family protein [Mycobacterium tuberculosis SUMu002]
 19 more sequence titles
 
gi|308371205|ref|ZP_07667108.1| PPE family protein [Mycobacterium tuberculosis SUMu003]
 gi|308371207|ref|ZP_07667109.1| PPE family protein [Mycobacterium tuberculosis SUMu003]
 gi|308372401|ref|ZP_07667371.1| PPE family protein [Mycobacterium tuberculosis SUMu004]
 gi|308373604|ref|ZP_07433021.2| hypothetical protein TMEG_02292 [Mycobacterium tuberculosis SUMu005]
 gi|308374701|ref|ZP_07437029.2| hypothetical protein TMFG_04062 [Mycobacterium tuberculosis SUMu006]
 gi|308374754|ref|ZP_07437263.2| hypothetical protein TMFG_00222 [Mycobacterium tuberculosis SUMu006]
 gi|308379386|ref|ZP_07668956.1| PPE family protein [Mycobacterium tuberculosis SUMu010]
 gi|308380549|ref|ZP_07669215.1| hypothetical protein TMKG_04056 [Mycobacterium tuberculosis SUMu011]
 gi|308214319|gb|EFO73718.1| PPE family protein [Mycobacterium tuberculosis SUMu001]
 gi|308325967|gb|EFP14818.1| PPE family protein [Mycobacterium tuberculosis SUMu002]
 gi|308326371|gb|EFP15222.1| PPE family protein [Mycobacterium tuberculosis SUMu002]
 gi|308329492|gb|EFP18343.1| PPE family protein [Mycobacterium tuberculosis SUMu003]
 gi|308329498|gb|EFP18349.1| PPE family protein [Mycobacterium tuberculosis SUMu003]
 gi|308333339|gb|EFP22190.1| PPE family protein [Mycobacterium tuberculosis SUMu004]
 gi|308336993|gb|EFP25844.1| hypothetical protein TMEG_02292 [Mycobacterium tuberculosis SUMu005]
 gi|308340807|gb|EFP29658.1| hypothetical protein TMFG_00222 [Mycobacterium tuberculosis SUMu006]
 gi|308341021|gb|EFP29872.1| hypothetical protein TMFG_04062 [Mycobacterium tuberculosis SUMu006]
 gi|308357187|gb|EFP46038.1| PPE family protein [Mycobacterium tuberculosis SUMu010]
 gi|308361139|gb|EFP49990.1| hypothetical protein TMKG_04056 [Mycobacterium tuberculosis SUMu011]
Length=39

 Score = 50.1 bits (118),  Expect = 1e-04, Method: Compositional matrix adjust.
 Identities = 28/28 (100%), Positives = 28/28 (100%), Gaps = 0/28 (0%)

Query  1   VTLSVVPEGLAAASAAVEALTARLAAAH  28
           VTLSVVPEGLAAASAAVEALTARLAAAH
Sbjct  12  VTLSVVPEGLAAASAAVEALTARLAAAH  39


>gi|240171484|ref|ZP_04750143.1| PE domain-containing protein [Mycobacterium kansasii ATCC 12478]
Length=113

 Score = 40.0 bits (92),  Expect = 0.11, Method: Compositional matrix adjust.
 Identities = 21/24 (88%), Positives = 22/24 (92%), Gaps = 0/24 (0%)

Query  1   VTLSVVPEGLAAASAAVEALTARL  24
           VTLSVVPEGL AASAA+EALT RL
Sbjct  12  VTLSVVPEGLIAASAAIEALTTRL  35


>gi|15827194|ref|NP_301457.1| PE-family protein [Mycobacterium leprae TN]
 gi|221229672|ref|YP_002503088.1| PE-family protein [Mycobacterium leprae Br4923]
 gi|13092742|emb|CAC30046.1| PE-family protein [Mycobacterium leprae]
 gi|219932779|emb|CAR70631.1| PE-family protein [Mycobacterium leprae Br4923]
Length=102

 Score = 37.7 bits (86),  Expect = 0.57, Method: Compositional matrix adjust.
 Identities = 18/28 (65%), Positives = 21/28 (75%), Gaps = 0/28 (0%)

Query  1   VTLSVVPEGLAAASAAVEALTARLAAAH  28
           +TL V+PEGL  ASA +EALTA LA  H
Sbjct  1   MTLGVIPEGLEGASAVIEALTAHLATVH  28


>gi|254821558|ref|ZP_05226559.1| PE family protein [Mycobacterium intracellulare ATCC 13950]
Length=102

 Score = 35.4 bits (80),  Expect = 2.7, Method: Compositional matrix adjust.
 Identities = 18/24 (75%), Positives = 22/24 (92%), Gaps = 0/24 (0%)

Query  1   VTLSVVPEGLAAASAAVEALTARL  24
           +TL V+PEGLAA SAAVEA+TA+L
Sbjct  1   MTLRVLPEGLAATSAAVEAITAQL  24


>gi|212596236|gb|ACJ35562.1| PE1 [Mycobacterium intracellulare ATCC 13950]
Length=105

 Score = 35.4 bits (80),  Expect = 2.7, Method: Compositional matrix adjust.
 Identities = 18/24 (75%), Positives = 22/24 (92%), Gaps = 0/24 (0%)

Query  1   VTLSVVPEGLAAASAAVEALTARL  24
           +TL V+PEGLAA SAAVEA+TA+L
Sbjct  4   MTLRVLPEGLAATSAAVEAITAQL  27


>gi|148824209|ref|YP_001288963.1| PE family protein [Mycobacterium tuberculosis F11]
 gi|148722736|gb|ABR07361.1| PE family protein [Mycobacterium tuberculosis F11]
Length=67

 Score = 35.4 bits (80),  Expect = 2.8, Method: Compositional matrix adjust.
 Identities = 27/28 (97%), Positives = 27/28 (97%), Gaps = 0/28 (0%)

Query  1   VTLSVVPEGLAAASAAVEALTARLAAAH  28
           VTL VVPEGLAAASAAVEALTARLAAAH
Sbjct  40  VTLRVVPEGLAAASAAVEALTARLAAAH  67


>gi|41406220|ref|NP_959056.1| hypothetical protein MAP0122 [Mycobacterium avium subsp. paratuberculosis 
K-10]
 gi|118464188|ref|YP_879413.1| PE family protein [Mycobacterium avium 104]
 gi|41394568|gb|AAS02439.1| PE_1 [Mycobacterium avium subsp. paratuberculosis K-10]
 gi|118165475|gb|ABK66372.1| PE family protein [Mycobacterium avium 104]
 gi|336458087|gb|EGO37073.1| PE family protein [Mycobacterium avium subsp. paratuberculosis 
S397]
Length=101

 Score = 35.4 bits (80),  Expect = 3.0, Method: Compositional matrix adjust.
 Identities = 17/24 (71%), Positives = 22/24 (92%), Gaps = 0/24 (0%)

Query  1   VTLSVVPEGLAAASAAVEALTARL  24
           +TL V+PEGLAA SAAV+A+TA+L
Sbjct  1   MTLRVIPEGLAATSAAVDAITAQL  24


>gi|339633026|ref|YP_004724668.1| PE family protein [Mycobacterium africanum GM041182]
 gi|31619791|emb|CAD96731.1| PE family protein [Mycobacterium bovis AF2122/97]
 gi|41352775|emb|CAE55539.1| PE FAMILY PROTEIN [Mycobacterium tuberculosis H37Rv]
 gi|121494549|emb|CAL73030.1| PE family protein [Mycobacterium bovis BCG str. Pasteur 1173P2]
 gi|224774508|dbj|BAH27314.1| PE family protein [Mycobacterium bovis BCG str. Tokyo 172]
 gi|339332382|emb|CCC28095.1| PE family protein [Mycobacterium africanum GM041182]
 gi|341602940|emb|CCC65618.1| PE family protein [Mycobacterium bovis BCG str. Moreau RDJ]
Length=28

 Score = 35.0 bits (79),  Expect = 3.8, Method: Compositional matrix adjust.
 Identities = 27/28 (97%), Positives = 28/28 (100%), Gaps = 0/28 (0%)

Query  1   VTLSVVPEGLAAASAAVEALTARLAAAH  28
           +TLSVVPEGLAAASAAVEALTARLAAAH
Sbjct  1   MTLSVVPEGLAAASAAVEALTARLAAAH  28


>gi|342860175|ref|ZP_08716827.1| PE family protein [Mycobacterium colombiense CECT 3035]
 gi|342132553|gb|EGT85782.1| PE family protein [Mycobacterium colombiense CECT 3035]
Length=101

 Score = 34.3 bits (77),  Expect = 6.3, Method: Compositional matrix adjust.
 Identities = 17/24 (71%), Positives = 22/24 (92%), Gaps = 0/24 (0%)

Query  1   VTLSVVPEGLAAASAAVEALTARL  24
           +TL V+PEGLAA SAAV+A+TA+L
Sbjct  1   MTLRVLPEGLAATSAAVDAITAQL  24


>gi|254773162|ref|ZP_05214678.1| PE family protein [Mycobacterium avium subsp. avium ATCC 25291]
 gi|212595728|gb|ACJ35519.1| PE1 [Mycobacterium avium subsp. avium]
Length=101

 Score = 33.9 bits (76),  Expect = 9.3, Method: Compositional matrix adjust.
 Identities = 16/24 (67%), Positives = 21/24 (88%), Gaps = 0/24 (0%)

Query  1   VTLSVVPEGLAAASAAVEALTARL  24
           +TL V+PEGLAA SAAV+ +TA+L
Sbjct  1   MTLRVIPEGLAATSAAVDVITAQL  24



Lambda     K      H
   0.312    0.117    0.291 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Effective search space used: 129353535850


  Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
    Posted date:  Sep 5, 2011  4:36 AM
  Number of letters in database: 5,219,829,388
  Number of sequences in database:  15,229,318



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40