BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv3055 Length=204 Score E Sequences producing significant alignments: (Bits) Value gi|15842622|ref|NP_337659.1| TetR family transcriptional regulat... 404 3e-111 gi|289553154|ref|ZP_06442364.1| transcriptional regulator, tetR-... 401 3e-110 gi|15610192|ref|NP_217571.1| TetR family transcriptional regulat... 400 5e-110 gi|289448734|ref|ZP_06438478.1| transcriptional regulator, tetR-... 398 2e-109 gi|297635686|ref|ZP_06953466.1| TetR family transcriptional regu... 390 7e-107 gi|308232328|ref|ZP_07415698.2| transcriptional regulator, tetR-... 340 8e-92 gi|118618714|ref|YP_907046.1| TetR family transcriptional regula... 322 2e-86 gi|183981651|ref|YP_001849942.1| TetR family transcriptional reg... 321 4e-86 gi|254820777|ref|ZP_05225778.1| transcriptional regulator, TetR ... 295 4e-78 gi|296171149|ref|ZP_06852597.1| TetR family transcriptional regu... 294 4e-78 gi|240171833|ref|ZP_04750492.1| putative transcriptional regulat... 290 1e-76 gi|342858094|ref|ZP_08714749.1| TetR family transcriptional regu... 280 8e-74 gi|289444619|ref|ZP_06434363.1| transcriptional regulator [Mycob... 266 1e-69 gi|118466680|ref|YP_883085.1| TetR family transcriptional regula... 252 2e-65 gi|254776342|ref|ZP_05217858.1| hypothetical protein MaviaA2_169... 251 3e-65 gi|41409203|ref|NP_962039.1| hypothetical protein MAP3105 [Mycob... 251 4e-65 gi|118468360|ref|YP_886645.1| TetR family transcriptional regula... 214 4e-54 gi|120403032|ref|YP_952861.1| TetR family transcriptional regula... 209 2e-52 gi|108798781|ref|YP_638978.1| TetR family transcriptional regula... 200 1e-49 gi|145224888|ref|YP_001135566.1| TetR family transcriptional reg... 193 1e-47 gi|169630499|ref|YP_001704148.1| TetR family transcriptional reg... 176 2e-42 gi|312140545|ref|YP_004007881.1| tetr family transcriptional reg... 163 1e-38 gi|325675835|ref|ZP_08155519.1| TetR family transcriptional regu... 163 2e-38 gi|326381476|ref|ZP_08203170.1| regulatory protein TetR [Gordoni... 161 5e-38 gi|226365898|ref|YP_002783681.1| TetR family transcriptional reg... 155 3e-36 gi|111023396|ref|YP_706368.1| TetR family transcriptional regula... 149 2e-34 gi|269796710|ref|YP_003316165.1| transcriptional regulator [Sang... 143 2e-32 gi|262203182|ref|YP_003274390.1| TetR family transcriptional reg... 141 5e-32 gi|343926909|ref|ZP_08766402.1| putative TetR family transcripti... 139 2e-31 gi|320009963|gb|ADW04813.1| regulatory protein TetR [Streptomyce... 139 3e-31 gi|329939547|ref|ZP_08288848.1| TetR family transcriptional regu... 138 5e-31 gi|336120102|ref|YP_004574880.1| putative TetR family transcript... 137 8e-31 gi|257056040|ref|YP_003133872.1| transcriptional regulator, TetR... 134 8e-30 gi|345009063|ref|YP_004811417.1| regulatory protein TetR [Strept... 132 2e-29 gi|297154949|gb|ADI04661.1| putative type I polyketide synthase ... 128 4e-28 gi|54026282|ref|YP_120524.1| putative transcriptional regulator ... 128 4e-28 gi|296140665|ref|YP_003647908.1| TetR family transcriptional reg... 127 7e-28 gi|119717584|ref|YP_924549.1| regulatory protein TetR [Nocardioi... 127 8e-28 gi|290962093|ref|YP_003493275.1| TetR family transcriptional reg... 126 2e-27 gi|300786745|ref|YP_003767036.1| TetR family transcriptional reg... 123 2e-26 gi|152965537|ref|YP_001361321.1| TetR family transcriptional reg... 122 2e-26 gi|345000596|ref|YP_004803450.1| TetR family transcriptional reg... 122 3e-26 gi|311895324|dbj|BAJ27732.1| putative TetR family transcriptiona... 122 5e-26 gi|325965157|ref|YP_004243063.1| TetR family transcriptional reg... 121 7e-26 gi|226305834|ref|YP_002765794.1| TetR family transcriptional reg... 120 1e-25 gi|229493352|ref|ZP_04387141.1| transcriptional regulator, TetR ... 120 2e-25 gi|297563208|ref|YP_003682182.1| TetR family transcriptional reg... 118 5e-25 gi|29833588|ref|NP_828222.1| TetR family transcriptional regulat... 116 2e-24 gi|116672560|ref|YP_833493.1| TetR family transcriptional regula... 115 4e-24 gi|119963194|ref|YP_949556.1| TetR family transcriptional regula... 113 2e-23 >gi|15842622|ref|NP_337659.1| TetR family transcriptional regulator [Mycobacterium tuberculosis CDC1551] gi|13882937|gb|AAK47473.1| transcriptional regulator, TetR family [Mycobacterium tuberculosis CDC1551] Length=276 Score = 404 bits (1039), Expect = 3e-111, Method: Compositional matrix adjust. Identities = 204/204 (100%), Positives = 204/204 (100%), Gaps = 0/204 (0%) Query 1 VSGAERLGDLPVFARQEPVPERGDAARNRALLLEAARRLIARSGADAITMDDVAAAAGVG 60 VSGAERLGDLPVFARQEPVPERGDAARNRALLLEAARRLIARSGADAITMDDVAAAAGVG Sbjct 73 VSGAERLGDLPVFARQEPVPERGDAARNRALLLEAARRLIARSGADAITMDDVAAAAGVG 132 Query 61 KGTLFRRFGSRAGLMMVLLDEDERASQQAFLFGPPPLGPDAPPLDRLIAFGRERMRFVHA 120 KGTLFRRFGSRAGLMMVLLDEDERASQQAFLFGPPPLGPDAPPLDRLIAFGRERMRFVHA Sbjct 133 KGTLFRRFGSRAGLMMVLLDEDERASQQAFLFGPPPLGPDAPPLDRLIAFGRERMRFVHA 192 Query 121 HHQLLSEANRDPQTRHSAALSVLRTHLRVLLASAPTTGDLDAQTDALLALLDVDYVEHQL 180 HHQLLSEANRDPQTRHSAALSVLRTHLRVLLASAPTTGDLDAQTDALLALLDVDYVEHQL Sbjct 193 HHQLLSEANRDPQTRHSAALSVLRTHLRVLLASAPTTGDLDAQTDALLALLDVDYVEHQL 252 Query 181 NAGGHTLQTLGDAWESLARKLCGR 204 NAGGHTLQTLGDAWESLARKLCGR Sbjct 253 NAGGHTLQTLGDAWESLARKLCGR 276 >gi|289553154|ref|ZP_06442364.1| transcriptional regulator, tetR-family [Mycobacterium tuberculosis KZN 605] gi|289437786|gb|EFD20279.1| transcriptional regulator, tetR-family [Mycobacterium tuberculosis KZN 605] Length=223 Score = 401 bits (1030), Expect = 3e-110, Method: Compositional matrix adjust. Identities = 204/204 (100%), Positives = 204/204 (100%), Gaps = 0/204 (0%) Query 1 VSGAERLGDLPVFARQEPVPERGDAARNRALLLEAARRLIARSGADAITMDDVAAAAGVG 60 VSGAERLGDLPVFARQEPVPERGDAARNRALLLEAARRLIARSGADAITMDDVAAAAGVG Sbjct 20 VSGAERLGDLPVFARQEPVPERGDAARNRALLLEAARRLIARSGADAITMDDVAAAAGVG 79 Query 61 KGTLFRRFGSRAGLMMVLLDEDERASQQAFLFGPPPLGPDAPPLDRLIAFGRERMRFVHA 120 KGTLFRRFGSRAGLMMVLLDEDERASQQAFLFGPPPLGPDAPPLDRLIAFGRERMRFVHA Sbjct 80 KGTLFRRFGSRAGLMMVLLDEDERASQQAFLFGPPPLGPDAPPLDRLIAFGRERMRFVHA 139 Query 121 HHQLLSEANRDPQTRHSAALSVLRTHLRVLLASAPTTGDLDAQTDALLALLDVDYVEHQL 180 HHQLLSEANRDPQTRHSAALSVLRTHLRVLLASAPTTGDLDAQTDALLALLDVDYVEHQL Sbjct 140 HHQLLSEANRDPQTRHSAALSVLRTHLRVLLASAPTTGDLDAQTDALLALLDVDYVEHQL 199 Query 181 NAGGHTLQTLGDAWESLARKLCGR 204 NAGGHTLQTLGDAWESLARKLCGR Sbjct 200 NAGGHTLQTLGDAWESLARKLCGR 223 >gi|15610192|ref|NP_217571.1| TetR family transcriptional regulator [Mycobacterium tuberculosis H37Rv] gi|31794233|ref|NP_856726.1| TetR family transcriptional regulator [Mycobacterium bovis AF2122/97] gi|121638940|ref|YP_979164.1| TetR family transcriptional regulator [Mycobacterium bovis BCG str. Pasteur 1173P2] 55 more sequence titles Length=204 Score = 400 bits (1028), Expect = 5e-110, Method: Compositional matrix adjust. Identities = 203/204 (99%), Positives = 204/204 (100%), Gaps = 0/204 (0%) Query 1 VSGAERLGDLPVFARQEPVPERGDAARNRALLLEAARRLIARSGADAITMDDVAAAAGVG 60 +SGAERLGDLPVFARQEPVPERGDAARNRALLLEAARRLIARSGADAITMDDVAAAAGVG Sbjct 1 MSGAERLGDLPVFARQEPVPERGDAARNRALLLEAARRLIARSGADAITMDDVAAAAGVG 60 Query 61 KGTLFRRFGSRAGLMMVLLDEDERASQQAFLFGPPPLGPDAPPLDRLIAFGRERMRFVHA 120 KGTLFRRFGSRAGLMMVLLDEDERASQQAFLFGPPPLGPDAPPLDRLIAFGRERMRFVHA Sbjct 61 KGTLFRRFGSRAGLMMVLLDEDERASQQAFLFGPPPLGPDAPPLDRLIAFGRERMRFVHA 120 Query 121 HHQLLSEANRDPQTRHSAALSVLRTHLRVLLASAPTTGDLDAQTDALLALLDVDYVEHQL 180 HHQLLSEANRDPQTRHSAALSVLRTHLRVLLASAPTTGDLDAQTDALLALLDVDYVEHQL Sbjct 121 HHQLLSEANRDPQTRHSAALSVLRTHLRVLLASAPTTGDLDAQTDALLALLDVDYVEHQL 180 Query 181 NAGGHTLQTLGDAWESLARKLCGR 204 NAGGHTLQTLGDAWESLARKLCGR Sbjct 181 NAGGHTLQTLGDAWESLARKLCGR 204 >gi|289448734|ref|ZP_06438478.1| transcriptional regulator, tetR-family [Mycobacterium tuberculosis CPHL_A] gi|289421692|gb|EFD18893.1| transcriptional regulator, tetR-family [Mycobacterium tuberculosis CPHL_A] Length=204 Score = 398 bits (1023), Expect = 2e-109, Method: Compositional matrix adjust. Identities = 201/204 (99%), Positives = 203/204 (99%), Gaps = 0/204 (0%) Query 1 VSGAERLGDLPVFARQEPVPERGDAARNRALLLEAARRLIARSGADAITMDDVAAAAGVG 60 +SGAERLGDLPVFARQEPVPERGDAARNRALLLEAARRLIARSGADAITMDDVAAAAGVG Sbjct 1 MSGAERLGDLPVFARQEPVPERGDAARNRALLLEAARRLIARSGADAITMDDVAAAAGVG 60 Query 61 KGTLFRRFGSRAGLMMVLLDEDERASQQAFLFGPPPLGPDAPPLDRLIAFGRERMRFVHA 120 KGTLFRRFGSRAGLMMVLLDEDERASQQAFLFGPPPLGPDAPPLDRLIAFGRERMRF+HA Sbjct 61 KGTLFRRFGSRAGLMMVLLDEDERASQQAFLFGPPPLGPDAPPLDRLIAFGRERMRFIHA 120 Query 121 HHQLLSEANRDPQTRHSAALSVLRTHLRVLLASAPTTGDLDAQTDALLALLDVDYVEHQL 180 HHQLLSEANRDPQTRHSAALSVLRTHLRVLLASAPTTGDLDAQTDALLALLDVDYVEHQL Sbjct 121 HHQLLSEANRDPQTRHSAALSVLRTHLRVLLASAPTTGDLDAQTDALLALLDVDYVEHQL 180 Query 181 NAGGHTLQTLGDAWESLARKLCGR 204 NAG HTLQTLGDAWESLARKLCGR Sbjct 181 NAGSHTLQTLGDAWESLARKLCGR 204 >gi|297635686|ref|ZP_06953466.1| TetR family transcriptional regulator [Mycobacterium tuberculosis KZN 4207] Length=198 Score = 390 bits (1002), Expect = 7e-107, Method: Compositional matrix adjust. Identities = 197/198 (99%), Positives = 198/198 (100%), Gaps = 0/198 (0%) Query 7 LGDLPVFARQEPVPERGDAARNRALLLEAARRLIARSGADAITMDDVAAAAGVGKGTLFR 66 +GDLPVFARQEPVPERGDAARNRALLLEAARRLIARSGADAITMDDVAAAAGVGKGTLFR Sbjct 1 MGDLPVFARQEPVPERGDAARNRALLLEAARRLIARSGADAITMDDVAAAAGVGKGTLFR 60 Query 67 RFGSRAGLMMVLLDEDERASQQAFLFGPPPLGPDAPPLDRLIAFGRERMRFVHAHHQLLS 126 RFGSRAGLMMVLLDEDERASQQAFLFGPPPLGPDAPPLDRLIAFGRERMRFVHAHHQLLS Sbjct 61 RFGSRAGLMMVLLDEDERASQQAFLFGPPPLGPDAPPLDRLIAFGRERMRFVHAHHQLLS 120 Query 127 EANRDPQTRHSAALSVLRTHLRVLLASAPTTGDLDAQTDALLALLDVDYVEHQLNAGGHT 186 EANRDPQTRHSAALSVLRTHLRVLLASAPTTGDLDAQTDALLALLDVDYVEHQLNAGGHT Sbjct 121 EANRDPQTRHSAALSVLRTHLRVLLASAPTTGDLDAQTDALLALLDVDYVEHQLNAGGHT 180 Query 187 LQTLGDAWESLARKLCGR 204 LQTLGDAWESLARKLCGR Sbjct 181 LQTLGDAWESLARKLCGR 198 >gi|308232328|ref|ZP_07415698.2| transcriptional regulator, tetR-family [Mycobacterium tuberculosis SUMu001] gi|308371223|ref|ZP_07424228.2| transcriptional regulator, tetR-family [Mycobacterium tuberculosis SUMu003] gi|308372415|ref|ZP_07428582.2| transcriptional regulator, tetR-family [Mycobacterium tuberculosis SUMu004] 13 more sequence titles Length=172 Score = 340 bits (872), Expect = 8e-92, Method: Compositional matrix adjust. Identities = 171/172 (99%), Positives = 172/172 (100%), Gaps = 0/172 (0%) Query 33 LEAARRLIARSGADAITMDDVAAAAGVGKGTLFRRFGSRAGLMMVLLDEDERASQQAFLF 92 +EAARRLIARSGADAITMDDVAAAAGVGKGTLFRRFGSRAGLMMVLLDEDERASQQAFLF Sbjct 1 MEAARRLIARSGADAITMDDVAAAAGVGKGTLFRRFGSRAGLMMVLLDEDERASQQAFLF 60 Query 93 GPPPLGPDAPPLDRLIAFGRERMRFVHAHHQLLSEANRDPQTRHSAALSVLRTHLRVLLA 152 GPPPLGPDAPPLDRLIAFGRERMRFVHAHHQLLSEANRDPQTRHSAALSVLRTHLRVLLA Sbjct 61 GPPPLGPDAPPLDRLIAFGRERMRFVHAHHQLLSEANRDPQTRHSAALSVLRTHLRVLLA 120 Query 153 SAPTTGDLDAQTDALLALLDVDYVEHQLNAGGHTLQTLGDAWESLARKLCGR 204 SAPTTGDLDAQTDALLALLDVDYVEHQLNAGGHTLQTLGDAWESLARKLCGR Sbjct 121 SAPTTGDLDAQTDALLALLDVDYVEHQLNAGGHTLQTLGDAWESLARKLCGR 172 >gi|118618714|ref|YP_907046.1| TetR family transcriptional regulator [Mycobacterium ulcerans Agy99] gi|118570824|gb|ABL05575.1| transcriptional regulatory protein (TetR- family) [Mycobacterium ulcerans Agy99] Length=220 Score = 322 bits (825), Expect = 2e-86, Method: Compositional matrix adjust. Identities = 166/204 (82%), Positives = 180/204 (89%), Gaps = 4/204 (1%) Query 1 VSGAERLGDLPVFARQEPVPERGDAARNRALLLEAARRLIARSGADAITMDDVAAAAGVG 60 VSG E LG+LPV ARQE RGDAARNR LLL+AARRL+A+ GA+A+T DD+AA AGVG Sbjct 21 VSGVEGLGELPVSARQE----RGDAARNRELLLQAARRLVAKRGAEAVTTDDIAAEAGVG 76 Query 61 KGTLFRRFGSRAGLMMVLLDEDERASQQAFLFGPPPLGPDAPPLDRLIAFGRERMRFVHA 120 KGTLFRRFGSRAGLMMVLLDEDERASQQAFLFGPPPLGP+A PLDRLIAFGRER+ FVHA Sbjct 77 KGTLFRRFGSRAGLMMVLLDEDERASQQAFLFGPPPLGPEAAPLDRLIAFGRERICFVHA 136 Query 121 HHQLLSEANRDPQTRHSAALSVLRTHLRVLLASAPTTGDLDAQTDALLALLDVDYVEHQL 180 HH+LLSEANR+P TR+ AA SV R H+RVLL SA TTGDLD QTDALLALLDVDYVEHQL Sbjct 137 HHELLSEANRNPLTRYGAAASVHRRHVRVLLESADTTGDLDVQTDALLALLDVDYVEHQL 196 Query 181 NAGGHTLQTLGDAWESLARKLCGR 204 N GHTL+TLGDAWE LARKLCGR Sbjct 197 NDRGHTLRTLGDAWEDLARKLCGR 220 >gi|183981651|ref|YP_001849942.1| TetR family transcriptional regulator [Mycobacterium marinum M] gi|183174977|gb|ACC40087.1| transcriptional regulatory protein (TetR- family) [Mycobacterium marinum M] Length=200 Score = 321 bits (823), Expect = 4e-86, Method: Compositional matrix adjust. Identities = 165/204 (81%), Positives = 180/204 (89%), Gaps = 4/204 (1%) Query 1 VSGAERLGDLPVFARQEPVPERGDAARNRALLLEAARRLIARSGADAITMDDVAAAAGVG 60 +SG E LG+LPV ARQE RGDAARNR LLL+AARRL+A+ GA+A+T DD+AA AGVG Sbjct 1 MSGVEGLGELPVSARQE----RGDAARNRELLLQAARRLVAKRGAEAVTTDDIAAEAGVG 56 Query 61 KGTLFRRFGSRAGLMMVLLDEDERASQQAFLFGPPPLGPDAPPLDRLIAFGRERMRFVHA 120 KGTLFRRFGSRAGLMMVLLDEDERASQQAFLFGPPPLGP+A PLDRLIAFGRER+ FVHA Sbjct 57 KGTLFRRFGSRAGLMMVLLDEDERASQQAFLFGPPPLGPEAAPLDRLIAFGRERICFVHA 116 Query 121 HHQLLSEANRDPQTRHSAALSVLRTHLRVLLASAPTTGDLDAQTDALLALLDVDYVEHQL 180 HH+LLSEANR+P TR+ AA SV R H+RVLL SA TTGDLD QTDALLALLDVDYVEHQL Sbjct 117 HHELLSEANRNPLTRYGAAASVHRRHVRVLLESADTTGDLDVQTDALLALLDVDYVEHQL 176 Query 181 NAGGHTLQTLGDAWESLARKLCGR 204 N GHTL+TLGDAWE LARKLCGR Sbjct 177 NDRGHTLRTLGDAWEDLARKLCGR 200 >gi|254820777|ref|ZP_05225778.1| transcriptional regulator, TetR family protein [Mycobacterium intracellulare ATCC 13950] Length=204 Score = 295 bits (754), Expect = 4e-78, Method: Compositional matrix adjust. Identities = 165/204 (81%), Positives = 178/204 (88%), Gaps = 0/204 (0%) Query 1 VSGAERLGDLPVFARQEPVPERGDAARNRALLLEAARRLIARSGADAITMDDVAAAAGVG 60 +SG ER G+LP+ Q P ERGDA RNRALLL+AARRL+A GADA+TMDDVAAAAGVG Sbjct 1 MSGVERSGELPMCVPQLPAQERGDALRNRALLLDAARRLVAERGADAVTMDDVAAAAGVG 60 Query 61 KGTLFRRFGSRAGLMMVLLDEDERASQQAFLFGPPPLGPDAPPLDRLIAFGRERMRFVHA 120 KGTLFRRFGSRAGLMMVLLDEDERASQ+AFLFGPPPLGPDAPPLDRL+AFGRERMRF H Sbjct 61 KGTLFRRFGSRAGLMMVLLDEDERASQEAFLFGPPPLGPDAPPLDRLVAFGRERMRFAHT 120 Query 121 HHQLLSEANRDPQTRHSAALSVLRTHLRVLLASAPTTGDLDAQTDALLALLDVDYVEHQL 180 HH LLS ANRDP+TR+ +VLR H+RVLLASA T+GDL Q DALLALLD DYVEHQL Sbjct 121 HHALLSAANRDPRTRYGPPAAVLRRHVRVLLASAETSGDLVVQADALLALLDTDYVEHQL 180 Query 181 NAGGHTLQTLGDAWESLARKLCGR 204 N GGHTLQTLGDAWESLARKLCGR Sbjct 181 NDGGHTLQTLGDAWESLARKLCGR 204 >gi|296171149|ref|ZP_06852597.1| TetR family transcriptional regulator [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295894285|gb|EFG74040.1| TetR family transcriptional regulator [Mycobacterium parascrofulaceum ATCC BAA-614] Length=202 Score = 294 bits (753), Expect = 4e-78, Method: Compositional matrix adjust. Identities = 164/201 (82%), Positives = 180/201 (90%), Gaps = 0/201 (0%) Query 4 AERLGDLPVFARQEPVPERGDAARNRALLLEAARRLIARSGADAITMDDVAAAAGVGKGT 63 +ERL LPV+A Q ERGDAARNRALLL+AAR LIA GADA+TMDDVAAAAGVGKGT Sbjct 2 SERLDALPVWAPQAVHQERGDAARNRALLLQAARNLIAERGADAVTMDDVAAAAGVGKGT 61 Query 64 LFRRFGSRAGLMMVLLDEDERASQQAFLFGPPPLGPDAPPLDRLIAFGRERMRFVHAHHQ 123 LFRRFGSRAGLM+VLLDE+ERASQQAFLFGPPPLGPDAPPLDRL+AFGRER+RFVHAHH+ Sbjct 62 LFRRFGSRAGLMLVLLDEEERASQQAFLFGPPPLGPDAPPLDRLVAFGRERIRFVHAHHE 121 Query 124 LLSEANRDPQTRHSAALSVLRTHLRVLLASAPTTGDLDAQTDALLALLDVDYVEHQLNAG 183 LLS ANRDPQ R++A +VLRTH+RVLL A T+G+LDAQTDALLALLDVDYVEHQL+ Sbjct 122 LLSAANRDPQNRYNAPATVLRTHVRVLLQEAHTSGNLDAQTDALLALLDVDYVEHQLHEA 181 Query 184 GHTLQTLGDAWESLARKLCGR 204 G T QTLGDAWESLARKLCGR Sbjct 182 GQTTQTLGDAWESLARKLCGR 202 >gi|240171833|ref|ZP_04750492.1| putative transcriptional regulatory protein [Mycobacterium kansasii ATCC 12478] Length=204 Score = 290 bits (741), Expect = 1e-76, Method: Compositional matrix adjust. Identities = 169/204 (83%), Positives = 177/204 (87%), Gaps = 0/204 (0%) Query 1 VSGAERLGDLPVFARQEPVPERGDAARNRALLLEAARRLIARSGADAITMDDVAAAAGVG 60 +S ER GDL RQEP ERGDAARNRALLL+AARRL+A+ GADAITMDDVAAAAGVG Sbjct 1 MSDVERPGDLRAPPRQEPPNERGDAARNRALLLDAARRLVAQRGADAITMDDVAAAAGVG 60 Query 61 KGTLFRRFGSRAGLMMVLLDEDERASQQAFLFGPPPLGPDAPPLDRLIAFGRERMRFVHA 120 KGTLFRRFGSRAGLMMVLLDEDER SQQAFLFGPPPLGPDAPPLDRLIAFGRER+ FVHA Sbjct 61 KGTLFRRFGSRAGLMMVLLDEDERTSQQAFLFGPPPLGPDAPPLDRLIAFGRERICFVHA 120 Query 121 HHQLLSEANRDPQTRHSAALSVLRTHLRVLLASAPTTGDLDAQTDALLALLDVDYVEHQL 180 H +LLSEA R TR+ AA V RTH+RVLL SA TTGDLD Q DALLALLDVDYVEH L Sbjct 121 HRELLSEAGRTRHTRYGAAALVHRTHVRVLLQSAHTTGDLDVQADALLALLDVDYVEHGL 180 Query 181 NAGGHTLQTLGDAWESLARKLCGR 204 N GGHTLQTLGDAWESLARKLCGR Sbjct 181 NDGGHTLQTLGDAWESLARKLCGR 204 >gi|342858094|ref|ZP_08714749.1| TetR family transcriptional regulator [Mycobacterium colombiense CECT 3035] gi|342133798|gb|EGT86978.1| TetR family transcriptional regulator [Mycobacterium colombiense CECT 3035] Length=202 Score = 280 bits (717), Expect = 8e-74, Method: Compositional matrix adjust. Identities = 160/201 (80%), Positives = 174/201 (87%), Gaps = 0/201 (0%) Query 4 AERLGDLPVFARQEPVPERGDAARNRALLLEAARRLIARSGADAITMDDVAAAAGVGKGT 63 +ER G+L VFA Q ERGDAARNRALLL+AAR L+A GADA+T DD+AAAAGVGKGT Sbjct 2 SERSGELHVFAPQVVHQERGDAARNRALLLQAARNLVAERGADAVTTDDIAAAAGVGKGT 61 Query 64 LFRRFGSRAGLMMVLLDEDERASQQAFLFGPPPLGPDAPPLDRLIAFGRERMRFVHAHHQ 123 LFRRFGSRAGLMMVLLDEDE+A QQAFLFGPPPLGP APP DRL+AFGRER+RF H H + Sbjct 62 LFRRFGSRAGLMMVLLDEDEQAVQQAFLFGPPPLGPGAPPADRLVAFGRERIRFAHDHCE 121 Query 124 LLSEANRDPQTRHSAALSVLRTHLRVLLASAPTTGDLDAQTDALLALLDVDYVEHQLNAG 183 LLS ANRDPQ RH+A VLRTH+RVLL +A +TGDLDAQTDALLALLDVDYVEHQL G Sbjct 122 LLSAANRDPQNRHNAPAMVLRTHVRVLLKAADSTGDLDAQTDALLALLDVDYVEHQLAEG 181 Query 184 GHTLQTLGDAWESLARKLCGR 204 GHTL TLGDAWESLARKLCGR Sbjct 182 GHTLTTLGDAWESLARKLCGR 202 >gi|289444619|ref|ZP_06434363.1| transcriptional regulator [Mycobacterium tuberculosis T46] gi|289417538|gb|EFD14778.1| transcriptional regulator [Mycobacterium tuberculosis T46] Length=214 Score = 266 bits (681), Expect = 1e-69, Method: Compositional matrix adjust. Identities = 137/138 (99%), Positives = 138/138 (100%), Gaps = 0/138 (0%) Query 33 LEAARRLIARSGADAITMDDVAAAAGVGKGTLFRRFGSRAGLMMVLLDEDERASQQAFLF 92 +EAARRLIARSGADAITMDDVAAAAGVGKGTLFRRFGSRAGLMMVLLDEDERASQQAFLF Sbjct 1 MEAARRLIARSGADAITMDDVAAAAGVGKGTLFRRFGSRAGLMMVLLDEDERASQQAFLF 60 Query 93 GPPPLGPDAPPLDRLIAFGRERMRFVHAHHQLLSEANRDPQTRHSAALSVLRTHLRVLLA 152 GPPPLGPDAPPLDRLIAFGRERMRFVHAHHQLLSEANRDPQTRHSAALSVLRTHLRVLLA Sbjct 61 GPPPLGPDAPPLDRLIAFGRERMRFVHAHHQLLSEANRDPQTRHSAALSVLRTHLRVLLA 120 Query 153 SAPTTGDLDAQTDALLAL 170 SAPTTGDLDAQTDALLAL Sbjct 121 SAPTTGDLDAQTDALLAL 138 >gi|118466680|ref|YP_883085.1| TetR family transcriptional regulator [Mycobacterium avium 104] gi|118167967|gb|ABK68864.1| transcriptional regulator, TetR family protein [Mycobacterium avium 104] Length=204 Score = 252 bits (644), Expect = 2e-65, Method: Compositional matrix adjust. Identities = 161/203 (80%), Positives = 174/203 (86%), Gaps = 0/203 (0%) Query 1 VSGAERLGDLPVFARQEPVPERGDAARNRALLLEAARRLIARSGADAITMDDVAAAAGVG 60 +SG E+ G L + P PERGDAARNRALLL+AARRL+A GADA+TMDDVAAAAGVG Sbjct 1 MSGVEQRGQLRFCDPRVPAPERGDAARNRALLLDAARRLVAERGADAVTMDDVAAAAGVG 60 Query 61 KGTLFRRFGSRAGLMMVLLDEDERASQQAFLFGPPPLGPDAPPLDRLIAFGRERMRFVHA 120 KGTLFRRFGSRAGLMMVLLDEDERA QQAFLFGPPPLGPDAPPLDRL+AFGRER+RF H Sbjct 61 KGTLFRRFGSRAGLMMVLLDEDERAIQQAFLFGPPPLGPDAPPLDRLVAFGRERLRFAHT 120 Query 121 HHQLLSEANRDPQTRHSAALSVLRTHLRVLLASAPTTGDLDAQTDALLALLDVDYVEHQL 180 HH LLS ANRDP+TR+ +VLR H+RVLLA+ TTGDLDAQ DALLALLD DYV HQL Sbjct 121 HHALLSAANRDPRTRYGPPSAVLRRHVRVLLAATHTTGDLDAQADALLALLDADYVHHQL 180 Query 181 NAGGHTLQTLGDAWESLARKLCG 203 N GHTLQTLGDAWESLARKLCG Sbjct 181 NDHGHTLQTLGDAWESLARKLCG 203 >gi|254776342|ref|ZP_05217858.1| hypothetical protein MaviaA2_16972 [Mycobacterium avium subsp. avium ATCC 25291] Length=204 Score = 251 bits (642), Expect = 3e-65, Method: Compositional matrix adjust. Identities = 161/203 (80%), Positives = 175/203 (87%), Gaps = 0/203 (0%) Query 1 VSGAERLGDLPVFARQEPVPERGDAARNRALLLEAARRLIARSGADAITMDDVAAAAGVG 60 +SG E+ G L + P PERGDAARNRALLL+AARRL+A GADA+TMDDVAAAAGVG Sbjct 1 MSGVEQRGQLRFCDPRVPAPERGDAARNRALLLDAARRLVAERGADAVTMDDVAAAAGVG 60 Query 61 KGTLFRRFGSRAGLMMVLLDEDERASQQAFLFGPPPLGPDAPPLDRLIAFGRERMRFVHA 120 KGTLFRRFGSRAGLMMVLLDEDERA QQAFLFGPPPLGPDAPPLDRL+AFGRER+RF H Sbjct 61 KGTLFRRFGSRAGLMMVLLDEDERAIQQAFLFGPPPLGPDAPPLDRLVAFGRERLRFAHT 120 Query 121 HHQLLSEANRDPQTRHSAALSVLRTHLRVLLASAPTTGDLDAQTDALLALLDVDYVEHQL 180 HH LLS ANRDP+TR+ +VLR H+RVLLA+A TTGDLDAQ DALLALLD DYV HQL Sbjct 121 HHALLSAANRDPRTRYGPPSAVLRRHVRVLLAAAHTTGDLDAQADALLALLDADYVHHQL 180 Query 181 NAGGHTLQTLGDAWESLARKLCG 203 + GHTLQTLGDAWESLARKLCG Sbjct 181 SDHGHTLQTLGDAWESLARKLCG 203 >gi|41409203|ref|NP_962039.1| hypothetical protein MAP3105 [Mycobacterium avium subsp. paratuberculosis K-10] gi|41398023|gb|AAS05653.1| hypothetical protein MAP_3105 [Mycobacterium avium subsp. paratuberculosis K-10] gi|336459251|gb|EGO38196.1| transcriptional regulator [Mycobacterium avium subsp. paratuberculosis S397] Length=204 Score = 251 bits (641), Expect = 4e-65, Method: Compositional matrix adjust. Identities = 160/203 (79%), Positives = 175/203 (87%), Gaps = 0/203 (0%) Query 1 VSGAERLGDLPVFARQEPVPERGDAARNRALLLEAARRLIARSGADAITMDDVAAAAGVG 60 +SG E+ G L + P PERGDAARNRALLL+AARRL+A GADA+TMDDVAAAAGVG Sbjct 1 MSGVEQRGQLRFCDPRVPAPERGDAARNRALLLDAARRLVAERGADAVTMDDVAAAAGVG 60 Query 61 KGTLFRRFGSRAGLMMVLLDEDERASQQAFLFGPPPLGPDAPPLDRLIAFGRERMRFVHA 120 KGTLFRRFGSRAGLMMVLLDEDERA QQAFLFGPPPLGPDAPPLDRL+AFGRER+RF H Sbjct 61 KGTLFRRFGSRAGLMMVLLDEDERAIQQAFLFGPPPLGPDAPPLDRLVAFGRERLRFAHT 120 Query 121 HHQLLSEANRDPQTRHSAALSVLRTHLRVLLASAPTTGDLDAQTDALLALLDVDYVEHQL 180 HH LLS ANRDP+TR+ +VLR H+RVLLA+A TTGDLDAQ DALLALLD DYV HQ+ Sbjct 121 HHALLSAANRDPRTRYGPPSAVLRRHVRVLLAAAHTTGDLDAQADALLALLDADYVHHQI 180 Query 181 NAGGHTLQTLGDAWESLARKLCG 203 + GHTLQTLGDAWESLARKLCG Sbjct 181 SDHGHTLQTLGDAWESLARKLCG 203 >gi|118468360|ref|YP_886645.1| TetR family transcriptional regulator [Mycobacterium smegmatis str. MC2 155] gi|118473721|ref|YP_885416.1| TetR family transcriptional regulator [Mycobacterium smegmatis str. MC2 155] gi|118169647|gb|ABK70543.1| transcriptional regulator, TetR family protein [Mycobacterium smegmatis str. MC2 155] gi|118175008|gb|ABK75904.1| transcriptional regulator, TetR family protein [Mycobacterium smegmatis str. MC2 155] Length=204 Score = 214 bits (546), Expect = 4e-54, Method: Compositional matrix adjust. Identities = 123/183 (68%), Positives = 145/183 (80%), Gaps = 1/183 (0%) Query 21 ERGDAARNRALLLEAARRLIARSGADAITMDDVAAAAGVGKGTLFRRFGSRAGLMMVLLD 80 ERGDAARNRA +L+AARRLIA G DA++ DD+A AGVGKGTLFRRFG+RAGLMMVLLD Sbjct 22 ERGDAARNRAAILDAARRLIAERGPDAVSTDDIAVEAGVGKGTLFRRFGTRAGLMMVLLD 81 Query 81 EDERASQQAFLFGPPPLGPDAPPLDRLIAFGRERMRFVHAHHQLLSEANRDPQTRHSAAL 140 EDE+A Q AF+FGPPPLGP APPLDRL+A+GRERM+FV HH LLS+A RDPQ R Sbjct 82 EDEKAHQDAFIFGPPPLGPGAPPLDRLLAYGRERMKFVREHHALLSDAARDPQARFGGPD 141 Query 141 SVLRTHLRVLLASAPTTGDLDAQTDALLALLDVDYVEHQLNAGGHTLQTLGDAWESLARK 200 ++ R+H+R+LL +A TTGDLDAQ DAL+ALLD DYV +QL G + + AW ARK Sbjct 142 TLHRSHVRMLLQAAGTTGDLDAQADALVALLDADYVAYQLER-GRSCEVQAAAWADTARK 200 Query 201 LCG 203 LCG Sbjct 201 LCG 203 >gi|120403032|ref|YP_952861.1| TetR family transcriptional regulator [Mycobacterium vanbaalenii PYR-1] gi|119955850|gb|ABM12855.1| transcriptional regulator, TetR family [Mycobacterium vanbaalenii PYR-1] Length=208 Score = 209 bits (533), Expect = 2e-52, Method: Compositional matrix adjust. Identities = 136/195 (70%), Positives = 161/195 (83%), Gaps = 1/195 (0%) Query 10 LPVFARQEPVP-ERGDAARNRALLLEAARRLIARSGADAITMDDVAAAAGVGKGTLFRRF 68 LPV + P ERGDAARNRALLL+AARRL+ GA+A+T DD+AAAAGVGKGTLFRRF Sbjct 13 LPVLPEGDSTPPERGDAARNRALLLDAARRLVDERGAEAVTTDDIAAAAGVGKGTLFRRF 72 Query 69 GSRAGLMMVLLDEDERASQQAFLFGPPPLGPDAPPLDRLIAFGRERMRFVHAHHQLLSEA 128 GSRAGLM+VLLDEDE+A QQAFLFGPPPLGP+APPL RL+A+GRER++FV +HH LLS+ Sbjct 73 GSRAGLMIVLLDEDEKALQQAFLFGPPPLGPEAPPLQRLLAYGRERLKFVDSHHALLSDV 132 Query 129 NRDPQTRHSAALSVLRTHLRVLLASAPTTGDLDAQTDALLALLDVDYVEHQLNAGGHTLQ 188 RD Q R +A ++ ++H+R+LL SA TTGDLDAQ ALLALLD DYV HQL+ G TL Sbjct 133 GRDLQMRFNAPATLHQSHVRLLLESAGTTGDLDAQATALLALLDADYVHHQLHDRGRTLA 192 Query 189 TLGDAWESLARKLCG 203 LGDAWE++ARKLCG Sbjct 193 ELGDAWETVARKLCG 207 >gi|108798781|ref|YP_638978.1| TetR family transcriptional regulator [Mycobacterium sp. MCS] gi|119867899|ref|YP_937851.1| TetR family transcriptional regulator [Mycobacterium sp. KMS] gi|126434382|ref|YP_001070073.1| TetR family transcriptional regulator [Mycobacterium sp. JLS] gi|108769200|gb|ABG07922.1| transcriptional regulator, TetR family [Mycobacterium sp. MCS] gi|119693988|gb|ABL91061.1| transcriptional regulator, TetR family [Mycobacterium sp. KMS] gi|126234182|gb|ABN97582.1| transcriptional regulator, TetR family [Mycobacterium sp. JLS] Length=200 Score = 200 bits (508), Expect = 1e-49, Method: Compositional matrix adjust. Identities = 139/204 (69%), Positives = 159/204 (78%), Gaps = 4/204 (1%) Query 1 VSGAERLGDLPVFARQEPVPERGDAARNRALLLEAARRLIARSGADAITMDDVAAAAGVG 60 +S +R LPV EP ERGDAARNR LLLEAARRLIA GA A++ DD+AAAAGVG Sbjct 1 MSAPDRFAPLPV--TDEP-QERGDAARNRLLLLEAARRLIAERGAGAVSTDDIAAAAGVG 57 Query 61 KGTLFRRFGSRAGLMMVLLDEDERASQQAFLFGPPPLGPDAPPLDRLIAFGRERMRFVHA 120 KGTLFRRFGSRAGLM+VLLDEDE+A QQAFLFGPPPLGP APPL+RL+A+GR R FVH Sbjct 58 KGTLFRRFGSRAGLMVVLLDEDEKAQQQAFLFGPPPLGPGAPPLERLLAYGRARHTFVHD 117 Query 121 HHQLLSEANRDPQTRHSAALSVLRTHLRVLLASAPTTGDLDAQTDALLALLDVDYVEHQL 180 H+ LLS+A RDPQTR + + H+R+LL SA TTGDLDAQT AL ALLD DY+EH+L Sbjct 118 HYALLSDAGRDPQTRFTGPFRLHHAHIRMLLQSAGTTGDLDAQTAALTALLDADYIEHRL 177 Query 181 NAGGHTLQTLGDAWESLARKLCGR 204 A G TL + DAWE +A KLCGR Sbjct 178 -ADGATLDEVADAWEVVAVKLCGR 200 >gi|145224888|ref|YP_001135566.1| TetR family transcriptional regulator [Mycobacterium gilvum PYR-GCK] gi|315445217|ref|YP_004078096.1| TetR family transcriptional regulator [Mycobacterium sp. Spyr1] gi|145217374|gb|ABP46778.1| transcriptional regulator, TetR family [Mycobacterium gilvum PYR-GCK] gi|315263520|gb|ADU00262.1| transcriptional regulator, TetR family [Mycobacterium sp. Spyr1] Length=209 Score = 193 bits (490), Expect = 1e-47, Method: Compositional matrix adjust. Identities = 130/208 (63%), Positives = 158/208 (76%), Gaps = 5/208 (2%) Query 1 VSGAERLGDLPVFARQEPVP-----ERGDAARNRALLLEAARRLIARSGADAITMDDVAA 55 +S E LPV + E P ERGDAARNR LLL+AARRL+ GAD++T DD+A Sbjct 1 MSAPENRNGLPVLSVAESGPSERAAERGDAARNRVLLLDAARRLVDERGADSVTTDDIAN 60 Query 56 AAGVGKGTLFRRFGSRAGLMMVLLDEDERASQQAFLFGPPPLGPDAPPLDRLIAFGRERM 115 AAGVGKGTLFRRFGSRAGLM+VLLDEDE+A Q A LFGPPPLGP APPL+RL+A+GR R+ Sbjct 61 AAGVGKGTLFRRFGSRAGLMIVLLDEDEKAQQHALLFGPPPLGPGAPPLERLLAYGRHRL 120 Query 116 RFVHAHHQLLSEANRDPQTRHSAALSVLRTHLRVLLASAPTTGDLDAQTDALLALLDVDY 175 +FV HH LLS+ RDPQ R +A +++ +H+R+LL A TTGDLDAQ ALLALLD DY Sbjct 121 KFVDTHHALLSDVGRDPQMRFNAPMTLHHSHVRLLLDEAETTGDLDAQAAALLALLDADY 180 Query 176 VEHQLNAGGHTLQTLGDAWESLARKLCG 203 V HQ G +L+++ DAWE++ARKLCG Sbjct 181 VHHQRTDLGRSLESIADAWETVARKLCG 208 >gi|169630499|ref|YP_001704148.1| TetR family transcriptional regulator [Mycobacterium abscessus ATCC 19977] gi|169242466|emb|CAM63494.1| Putative transcriptional regulator, TetR family [Mycobacterium abscessus] Length=217 Score = 176 bits (446), Expect = 2e-42, Method: Compositional matrix adjust. Identities = 109/190 (58%), Positives = 131/190 (69%), Gaps = 1/190 (0%) Query 16 QEPVPERGDAARNRALLLEAARRLIARSGADAITMDDVAAAAGVGKGTLFRRFGSRAGLM 75 Q PV ER A RNRALLL+AAR+L+ G D ++MD VA AAGVGKGTLFRRFGSR GL+ Sbjct 28 QNPVRERAIATRNRALLLDAARQLLDEVGPDGMSMDAVAHAAGVGKGTLFRRFGSRTGLL 87 Query 76 MVLLDEDERASQQAFLFGPPPLGPDAPPLDRLIAFGRERMRFVHAHHQLLSEANRDPQTR 135 + LLD +E QQAF+FGPPPLGPDAPPL RLIAFGR R+ F+ H L D Sbjct 88 LALLDHEEHIEQQAFMFGPPPLGPDAPPLTRLIAFGRARLAFLERHLDLARATTADTDAW 147 Query 136 HSAALSVL-RTHLRVLLASAPTTGDLDAQTDALLALLDVDYVEHQLNAGGHTLQTLGDAW 194 H+A ++L R H+R LLA TGDLDAQT AL++++D YV N+ G ++ LGDAW Sbjct 148 HNAPPTLLVRAHIRALLAQLECTGDLDAQTHALMSIIDPGYVYFATNSNGQSVAQLGDAW 207 Query 195 ESLARKLCGR 204 E L KLC R Sbjct 208 EDLVHKLCAR 217 >gi|312140545|ref|YP_004007881.1| tetr family transcriptional regulator [Rhodococcus equi 103S] gi|311889884|emb|CBH49201.1| putative TetR family transcriptional regulator [Rhodococcus equi 103S] Length=204 Score = 163 bits (413), Expect = 1e-38, Method: Compositional matrix adjust. Identities = 98/185 (53%), Positives = 119/185 (65%), Gaps = 1/185 (0%) Query 19 VPERGDAARNRALLLEAARRLIARSGADAITMDDVAAAAGVGKGTLFRRFGSRAGLMMVL 78 +PER DAARNR LLL+AA L+A G DA+TM+ VAA AGVGKGT+FRRFGSR+GLM L Sbjct 13 IPERCDAARNRKLLLDAAADLVAERGVDAVTMEAVAAKAGVGKGTVFRRFGSRSGLMNAL 72 Query 79 LDEDERASQQAFLFGPPPLGPDAPPLDRLIAFGRERMRFVHAHHQLLSEANRDPQTRHSA 138 LD ER Q AF+FGP PLGPDAPPLDRLIAFGR R+ V +L A P R Sbjct 73 LDHTERELQHAFMFGPAPLGPDAPPLDRLIAFGRARLDMVTVQGDVLRAAEGSPDVRFGG 132 Query 139 -ALSVLRTHLRVLLASAPTTGDLDAQTDALLALLDVDYVEHQLNAGGHTLQTLGDAWESL 197 A +V H+ LLA A GD++ ALLA L+ V HQ+ G + + + WE L Sbjct 133 PARAVSLRHVVTLLADAGVDGDVELLAVALLATLEAGLVLHQIRVLGISPARIANNWEDL 192 Query 198 ARKLC 202 AR++ Sbjct 193 ARRIT 197 >gi|325675835|ref|ZP_08155519.1| TetR family transcriptional regulator [Rhodococcus equi ATCC 33707] gi|325553806|gb|EGD23484.1| TetR family transcriptional regulator [Rhodococcus equi ATCC 33707] Length=207 Score = 163 bits (412), Expect = 2e-38, Method: Compositional matrix adjust. Identities = 98/185 (53%), Positives = 119/185 (65%), Gaps = 1/185 (0%) Query 19 VPERGDAARNRALLLEAARRLIARSGADAITMDDVAAAAGVGKGTLFRRFGSRAGLMMVL 78 +PER DAARNR LLL+AA L+A G DA+TM+ VAA AGVGKGT+FRRFGSR+GLM L Sbjct 16 IPERCDAARNRKLLLDAAADLVAERGVDAVTMEAVAAKAGVGKGTVFRRFGSRSGLMNAL 75 Query 79 LDEDERASQQAFLFGPPPLGPDAPPLDRLIAFGRERMRFVHAHHQLLSEANRDPQTRHSA 138 LD ER Q AF+FGP PLGPDAPPLDRLIAFGR R+ V +L A P R Sbjct 76 LDHTERELQHAFMFGPAPLGPDAPPLDRLIAFGRARLDMVTVQGDVLRAAEGSPDVRFGG 135 Query 139 -ALSVLRTHLRVLLASAPTTGDLDAQTDALLALLDVDYVEHQLNAGGHTLQTLGDAWESL 197 A +V H+ LLA A GD++ ALLA L+ V HQ+ G + + + WE L Sbjct 136 PARAVSLRHVVTLLADAGVDGDVELLAVALLATLEAGLVLHQIRVLGISPARIANNWEDL 195 Query 198 ARKLC 202 AR++ Sbjct 196 ARRIT 200 >gi|326381476|ref|ZP_08203170.1| regulatory protein TetR [Gordonia neofelifaecis NRRL B-59395] gi|326199723|gb|EGD56903.1| regulatory protein TetR [Gordonia neofelifaecis NRRL B-59395] Length=195 Score = 161 bits (408), Expect = 5e-38, Method: Compositional matrix adjust. Identities = 95/184 (52%), Positives = 114/184 (62%), Gaps = 1/184 (0%) Query 20 PERGDAARNRALLLEAARRLIARSGADAITMDDVAAAAGVGKGTLFRRFGSRAGLMMVLL 79 PER DAARNR LLL AA+ LI GA A+TMD VA AAGVGKGT+FRRFG+R GLM+ LL Sbjct 9 PERADAARNRRLLLAAAKSLIDSQGAAAVTMDAVARAAGVGKGTVFRRFGNRTGLMLALL 68 Query 80 DEDERASQQAFLFGPPPLGPDAPPLDRLIAFGRERMRFVHAHHQLLSEANRDPQTRHSAA 139 D E QQAFL GP PLGP A PLDRLIA+GR R++ H +L EA D S Sbjct 69 DHSESDLQQAFLSGPEPLGPGAAPLDRLIAYGRARLKMTVDHLDILLEAGADQPDHLSHP 128 Query 140 LSVLRT-HLRVLLASAPTTGDLDAQTDALLALLDVDYVEHQLNAGGHTLQTLGDAWESLA 198 + + T H+R+LLA G LD A+ A L V H L+ G + + D WES+ Sbjct 129 VWAMSTMHVRMLLAELGFAGRLDVTAHAVQAPLMAVTVRHLLDVVGMSPSEIADDWESMV 188 Query 199 RKLC 202 R+L Sbjct 189 RRLV 192 >gi|226365898|ref|YP_002783681.1| TetR family transcriptional regulator [Rhodococcus opacus B4] gi|226244388|dbj|BAH54736.1| putative TetR family transcriptional regulator [Rhodococcus opacus B4] Length=202 Score = 155 bits (392), Expect = 3e-36, Method: Compositional matrix adjust. Identities = 96/183 (53%), Positives = 121/183 (67%), Gaps = 1/183 (0%) Query 20 PERGDAARNRALLLEAARRLIARSGADAITMDDVAAAAGVGKGTLFRRFGSRAGLMMVLL 79 PERGDAARNR LLL+AA L+A G DA+TMD VA AGVGKGT+FRRFGSR+GLM LL Sbjct 17 PERGDAARNRRLLLDAAALLVAERGVDAVTMDAVACRAGVGKGTVFRRFGSRSGLMHALL 76 Query 80 DEDERASQQAFLFGPPPLGPDAPPLDRLIAFGRERMRFVHAHHQLLSEANRDPQTRHSA- 138 D ER QQ+F+FGPPPLGP A P+DRLIAFG R+ V ++ A + R +A Sbjct 77 DHTERELQQSFMFGPPPLGPGADPIDRLIAFGHARIAIVEVQGEVQRAAENSLEFRFAAP 136 Query 139 ALSVLRTHLRVLLASAPTTGDLDAQTDALLALLDVDYVEHQLNAGGHTLQTLGDAWESLA 198 A +V H+ LL +A GD + +LLA L+ V H+L G +++ LGDAWE L Sbjct 137 ARAVSVRHVVSLLRAAGVQGDHELLACSLLAPLEATLVLHELRDLGMSVERLGDAWEDLI 196 Query 199 RKL 201 R++ Sbjct 197 RRV 199 >gi|111023396|ref|YP_706368.1| TetR family transcriptional regulator [Rhodococcus jostii RHA1] gi|110822926|gb|ABG98210.1| possible transcriptional regulator, TetR family protein [Rhodococcus jostii RHA1] Length=199 Score = 149 bits (376), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 93/183 (51%), Positives = 119/183 (66%), Gaps = 1/183 (0%) Query 20 PERGDAARNRALLLEAARRLIARSGADAITMDDVAAAAGVGKGTLFRRFGSRAGLMMVLL 79 PERGDAARNR LLL+AA L+A G DA+TMD VA AGVGKGT+FRRFGSR+GLM LL Sbjct 14 PERGDAARNRRLLLDAAALLVAERGVDAVTMDAVACRAGVGKGTVFRRFGSRSGLMHALL 73 Query 80 DEDERASQQAFLFGPPPLGPDAPPLDRLIAFGRERMRFVHAHHQLLSEANRDPQTRHSA- 138 D ER QQ+F+FGPPPLGP A P+DRLIA+G R+ V ++ A + R +A Sbjct 74 DHTERELQQSFMFGPPPLGPGADPIDRLIAYGHARIAIVEVQGEVQRAAENSVEFRFAAP 133 Query 139 ALSVLRTHLRVLLASAPTTGDLDAQTDALLALLDVDYVEHQLNAGGHTLQTLGDAWESLA 198 A +V H+ LL +A D + +LLA L+ V H+L G +++ LG AWE L Sbjct 134 ARAVSVRHVVSLLRAAGVRCDHELLACSLLAPLEATLVLHELRDLGMSVERLGAAWEDLI 193 Query 199 RKL 201 R++ Sbjct 194 RRV 196 >gi|269796710|ref|YP_003316165.1| transcriptional regulator [Sanguibacter keddieii DSM 10542] gi|269098895|gb|ACZ23331.1| transcriptional regulator [Sanguibacter keddieii DSM 10542] Length=200 Score = 143 bits (360), Expect = 2e-32, Method: Compositional matrix adjust. Identities = 84/183 (46%), Positives = 109/183 (60%), Gaps = 1/183 (0%) Query 21 ERGDAARNRALLLEAARRLIARSGADAITMDDVAAAAGVGKGTLFRRFGSRAGLMMVLLD 80 ER DAARNR LL AR ++ G DA+TMD +A AAG+GKGT+FRRFGSRAGL+ LL+ Sbjct 16 ERADAARNREHLLVTARAIVDEVGVDALTMDGLARAAGLGKGTIFRRFGSRAGLLHDLLN 75 Query 81 EDERASQQAFLFGPPPLGPDAPPLDRLIAFGRERMRFVHAHHQLLSEANRDPQTRH-SAA 139 + E Q FL GP PLGP A P+DRL+AFGRER+R V +L + R+ + A Sbjct 76 DSELQFQHGFLSGPAPLGPGADPVDRLVAFGRERLRLVTVQGDILRSVESESALRYAAPA 135 Query 140 LSVLRTHLRVLLASAPTTGDLDAQTDALLALLDVDYVEHQLNAGGHTLQTLGDAWESLAR 199 + H+++LL A GDL T +L+ LD V + L L DAWE L R Sbjct 136 HAASAMHVQMLLGQAGVDGDLQVLTLTMLSSLDAALVLFETRDLQIDLDRLADAWEDLVR 195 Query 200 KLC 202 ++ Sbjct 196 RVT 198 >gi|262203182|ref|YP_003274390.1| TetR family transcriptional regulator [Gordonia bronchialis DSM 43247] gi|262086529|gb|ACY22497.1| regulatory protein TetR [Gordonia bronchialis DSM 43247] Length=208 Score = 141 bits (356), Expect = 5e-32, Method: Compositional matrix adjust. Identities = 88/185 (48%), Positives = 108/185 (59%), Gaps = 1/185 (0%) Query 21 ERGDAARNRALLLEAARRLIARSGADAITMDDVAAAAGVGKGTLFRRFGSRAGLMMVLLD 80 ER DAARNR LLL AA+ LI GA A+TMD VA AGVGKGT+FRRFGSR GLM+ LLD Sbjct 20 ERADAARNRRLLLAAAKNLIDNHGASAVTMDAVAREAGVGKGTVFRRFGSRTGLMLALLD 79 Query 81 EDERASQQAFLFGPPPLGPDAPPLDRLIAFGRERMRFVHAHHQLLSEANRDPQTRHSAAL 140 E QQAFL GP PLGP APPLDRL+A+GR R++ H +L EA S + Sbjct 80 HSESEIQQAFLSGPEPLGPGAPPLDRLLAYGRARLKLTADHLDILLEAGAASDDFMSHPV 139 Query 141 SVLRT-HLRVLLASAPTTGDLDAQTDALLALLDVDYVEHQLNAGGHTLQTLGDAWESLAR 199 T H+++LL LD + A+ A L V+H L+ G T+ W+ + Sbjct 140 WRASTQHVQLLLRQLGLGDQLDVVSVAVQAPLSASAVKHLLHDVGLDTDTITAQWQRMVV 199 Query 200 KLCGR 204 L R Sbjct 200 TLVNR 204 >gi|343926909|ref|ZP_08766402.1| putative TetR family transcriptional regulator [Gordonia alkanivorans NBRC 16433] gi|343763269|dbj|GAA13328.1| putative TetR family transcriptional regulator [Gordonia alkanivorans NBRC 16433] Length=215 Score = 139 bits (350), Expect = 2e-31, Method: Compositional matrix adjust. Identities = 84/184 (46%), Positives = 109/184 (60%), Gaps = 3/184 (1%) Query 21 ERGDAARNRALLLEAARRLIARSGADAITMDDVAAAAGVGKGTLFRRFGSRAGLMMVLLD 80 ER DAARNR LLL AA+ LI GA A+TM+ VA AGVGKGT+FRRFG+R GLM+ LLD Sbjct 27 ERADAARNRRLLLAAAKNLIDHHGAAAVTMEAVAREAGVGKGTVFRRFGNRTGLMLALLD 86 Query 81 EDERASQQAFLFGPPPLGPDAPPLDRLIAFGRERMRFVHAHHQLLSEAN--RDPQTRHSA 138 E QQA+L GP PLGP APPLDRL+A+GR R++ H +L EA D H Sbjct 87 HSESEMQQAYLSGPEPLGPGAPPLDRLLAYGRARLKLTCDHLDILLEAGAATDDFMTHPV 146 Query 139 ALSVLRTHLRVLLASAPTTGDLDAQTDALLALLDVDYVEHQLNAGGHTLQTLGDAWESLA 198 + + H+++LL DLD + A+ A L V + + G L+T+ W+ + Sbjct 147 GRASTQ-HVQILLRQLGFADDLDFMSLAVQAPLAAGSVRYLMVEVGLDLETITTQWQDMV 205 Query 199 RKLC 202 L Sbjct 206 TVLA 209 >gi|320009963|gb|ADW04813.1| regulatory protein TetR [Streptomyces flavogriseus ATCC 33331] Length=226 Score = 139 bits (349), Expect = 3e-31, Method: Compositional matrix adjust. Identities = 85/181 (47%), Positives = 104/181 (58%), Gaps = 1/181 (0%) Query 18 PVPERGDAARNRALLLEAARRLIARSGADAITMDDVAAAAGVGKGTLFRRFGSRAGLMMV 77 P R DAARNR LLL+AA RL+A GA +TM+ VAAAAGVGKGT+FRRF R GL++ Sbjct 38 PEALRADAARNRVLLLDAASRLLADCGAADLTMESVAAAAGVGKGTVFRRFKDRTGLLIA 97 Query 78 LLDEDERASQQAFLFGPPPLGPDAPPLDRLIAFGRERMRFVHAHHQLLSEANRDPQTRHS 137 LLD E Q AFL GPPP+GPDAP +RL AFG MR HH+L+ + DP S Sbjct 98 LLDHRESLLQAAFLSGPPPMGPDAPAAERLHAFGPAVMRHERDHHELILASRTDPLRTFS 157 Query 138 AALSVLR-THLRVLLASAPTTGDLDAQTDALLALLDVDYVEHQLNAGGHTLQTLGDAWES 196 LR +H+ +LL A G D LL +D V H G ++ L + W Sbjct 158 VPAQRLRLSHVTLLLRQAHAAGRPDLLAHTLLGSIDAPLVHHLTCERGMPVERLEEGWHD 217 Query 197 L 197 L Sbjct 218 L 218 >gi|329939547|ref|ZP_08288848.1| TetR family transcriptional regulator [Streptomyces griseoaurantiacus M045] gi|329301117|gb|EGG45012.1| TetR family transcriptional regulator [Streptomyces griseoaurantiacus M045] Length=199 Score = 138 bits (347), Expect = 5e-31, Method: Compositional matrix adjust. Identities = 80/193 (42%), Positives = 112/193 (59%), Gaps = 8/193 (4%) Query 17 EPVPERGDAARNRALLLEAARRLIARSGADAITMDDVAAAAGVGKGTLFRRFGSRAGLMM 76 +P ER DA RNR LL AR++IA G D +TMD +A A +GKGT+FRRFG+RAG+ Sbjct 5 KPRAERADAVRNREHLLRTARQMIAEEGVDKVTMDGLAERACLGKGTVFRRFGTRAGIFR 64 Query 77 VLLDEDERASQQAFLFGPPPLGPDAPPLDRLIAFGRERMRFVHAHHQLLSEANRDPQTRH 136 LLD DERA Q+ + GPPPLGP A P++RLIA+GR R+ F+ HH ++ + Sbjct 65 ALLDADERAFQEHAMSGPPPLGPGADPVERLIAYGRARVDFLTEHHAIVRACFDRSRPMI 124 Query 137 SAALSVLRTHLRVLLASAPTTGDLDAQTDALLALLDVDYV--------EHQLNAGGHTLQ 188 S+ + H+RVLL A + +LD L A L+ + E + T+ Sbjct 125 MGDPSMTQLHIRVLLREAGSVPNLDGVAVQLTAALEAPLLLYLSRPQREAESPDKDETIA 184 Query 189 TLGDAWESLARKL 201 LGDAW++L ++ Sbjct 185 FLGDAWQTLIERV 197 >gi|336120102|ref|YP_004574880.1| putative TetR family transcriptional regulator [Microlunatus phosphovorus NM-1] gi|334687892|dbj|BAK37477.1| putative TetR family transcriptional regulator [Microlunatus phosphovorus NM-1] Length=197 Score = 137 bits (346), Expect = 8e-31, Method: Compositional matrix adjust. Identities = 87/192 (46%), Positives = 117/192 (61%), Gaps = 9/192 (4%) Query 19 VPERGDAARNRALLLEAARRLIARSGADAITMDDVAAAAGVGKGTLFRRFGSRAGLMMVL 78 V ER DAARNRA+L+E AR ++A G D ITMD +A +G+GKGT+FRRFG+R+G+ M L Sbjct 6 VAERADAARNRAVLIETARAMLADVGVDKITMDALAERSGLGKGTVFRRFGTRSGIFMAL 65 Query 79 LDEDERASQQAFLFGPPPLGPDAPPLDRLIAFGRERMRFVHAHHQLLSEANRDPQT--RH 136 L + ERA Q+ L GPPPLGP A PLDRLIAFGR R+RF+ A ++ ++ A D +T Sbjct 66 LGDGERAFQKRVLSGPPPLGPGAEPLDRLIAFGRARLRFL-AENREIARAAFDGRTPVPF 124 Query 137 SAALSVLRTHLRVLLASAPT-TGDLDAQTDALLALLDVDYVEHQ-LNAGGHTLQTLGD-- 192 ++ + H+R LL A DLD A LDV + + L+ H+ +T D Sbjct 125 GPPTTMTQQHIRTLLEQAGIDAADLDILAMQFNAALDVPLLLYMPLDDSEHSAETFEDRL 184 Query 193 --AWESLARKLC 202 WE L +L Sbjct 185 ARGWEDLVARLS 196 >gi|257056040|ref|YP_003133872.1| transcriptional regulator, TetR family [Saccharomonospora viridis DSM 43017] gi|256585912|gb|ACU97045.1| transcriptional regulator, TetR family [Saccharomonospora viridis DSM 43017] Length=213 Score = 134 bits (337), Expect = 8e-30, Method: Compositional matrix adjust. Identities = 87/194 (45%), Positives = 105/194 (55%), Gaps = 1/194 (0%) Query 10 LPVFARQEPVPERGDAARNRALLLEAARRLIARSGADAITMDDVAAAAGVGKGTLFRRFG 69 L + R E +R DA RNRA +L+AA RL+AR GA +TMD VAA A VGKGT+FR FG Sbjct 19 LDLVNRHEHGGQRADAVRNRARVLDAATRLVARHGATNLTMDAVAAEASVGKGTVFRHFG 78 Query 70 SRAGLMMVLLDEDERASQQAFLFGPPPLGPDAPPLDRLIAFGRERMRFVHAHHQLLSEAN 129 R GL++ LLD E+ Q FL GPPPLGPDA P RL AFG +R H L A Sbjct 79 DRTGLLLALLDRAEQQLQARFLSGPPPLGPDADPSARLRAFGVAVLRHEQEHRDLYLAAE 138 Query 130 RDPQTRHSA-ALSVLRTHLRVLLASAPTTGDLDAQTDALLALLDVDYVEHQLNAGGHTLQ 188 D Q R A V TH+ +L+ S D + + ALL LD H L L+ Sbjct 139 LDVQRRFLAPPYRVRHTHVAMLVRSLDPRADAELLSHALLGYLDTALTHHLLQQRELELK 198 Query 189 TLGDAWESLARKLC 202 L W L +LC Sbjct 199 RLEAGWIELVTRLC 212 >gi|345009063|ref|YP_004811417.1| regulatory protein TetR [Streptomyces violaceusniger Tu 4113] gi|344035412|gb|AEM81137.1| regulatory protein TetR [Streptomyces violaceusniger Tu 4113] Length=202 Score = 132 bits (333), Expect = 2e-29, Method: Compositional matrix adjust. Identities = 87/200 (44%), Positives = 113/200 (57%), Gaps = 7/200 (3%) Query 9 DLPVFARQEPVPERGDAARNRALLLEAARRLIARSGADAITMDDVAAAAGVGKGTLFRRF 68 D PV +P ER DAARNR LL AR +IA GA+ +TMD +A AG+GKGT+FRRF Sbjct 2 DHPVVPLGQPRAERVDAARNRRRLLNTAREMIAEVGAEKVTMDGLAERAGLGKGTVFRRF 61 Query 69 GSRAGLMMVLLDEDERASQQAFLFGPPPLGPDAPPLDRLIAFGRERMRFVHAHHQLLSEA 128 +RAG+ LLDEDERA Q+ L+GPPPLGP A P +RLIA+GR R+ F+ H L A Sbjct 62 RTRAGVFHALLDEDERAFQEQVLYGPPPLGPGADPAERLIAYGRARIAFLLERHALARAA 121 Query 129 NRDPQTRHSAALSVLRTHLRVLLASA-PTTGDLDAQTDALLA-----LLDVDYVEHQLNA 182 Q + H+RVLL A P D D+ L A +L + + A Sbjct 122 LDRAQPIPAGEAVFSPAHIRVLLRQARPDCPDSDSLALQLAAALEGPILLYLVMPERAEA 181 Query 183 GGHTLQTLGDAWESLARKLC 202 H + L D+W+ L + +C Sbjct 182 TRH-FERLADSWQVLVQGVC 200 >gi|297154949|gb|ADI04661.1| putative type I polyketide synthase [Streptomyces bingchenggensis BCW-1] Length=1649 Score = 128 bits (322), Expect = 4e-28, Method: Compositional matrix adjust. Identities = 80/188 (43%), Positives = 113/188 (61%), Gaps = 7/188 (3%) Query 21 ERGDAARNRALLLEAARRLIARSGADAITMDDVAAAAGVGKGTLFRRFGSRAGLMMVLLD 80 ER DAARNR LLL R +IA G D +TMD +A +G+GKGT++RRFG+RAG+ +LD Sbjct 1449 ERADAARNRELLLRTTREMIAELGVDKVTMDGLAERSGLGKGTVYRRFGTRAGIFHAVLD 1508 Query 81 EDERASQQAFLFGPPPLGPDAPPLDRLIAFGRERMRFVHAHHQLLSEANRDPQTRHSAAL 140 +DERA Q+ L GP PLGP+A P+ RLIA+GR R+ F+ A + A + + Sbjct 1509 DDERAFQEHVLSGPAPLGPEAEPVARLIAYGRARISFLLARIAIARAALDRNRPVPAGEG 1568 Query 141 SVLRTHLRVLLASA-PTTGDLDAQTDALLALLDVDYVEH-----QLNAGGHTLQTLGDAW 194 SV + H+R+LL A P DLDA L A L+ + + + + H ++ L +W Sbjct 1569 SVSQFHIRMLLRQARPGFADLDALAVQLTAALEGPILLYLSMPEETDPSRH-VERLAGSW 1627 Query 195 ESLARKLC 202 ESL ++C Sbjct 1628 ESLVARIC 1635 >gi|54026282|ref|YP_120524.1| putative transcriptional regulator [Nocardia farcinica IFM 10152] gi|54017790|dbj|BAD59160.1| putative transcriptional regulator [Nocardia farcinica IFM 10152] Length=224 Score = 128 bits (322), Expect = 4e-28, Method: Compositional matrix adjust. Identities = 95/196 (49%), Positives = 127/196 (65%), Gaps = 3/196 (1%) Query 10 LPVFARQEPVPERGDAARNRALLLEAARRLIARSGADAITMDDVAAAAGVGKGTLFRRFG 69 +P+ EP ER DAARNR LLL+AA++L+ G D++TMD +A AGVGKGT+FRRFG Sbjct 24 VPLPGTGEP-GERADAARNRQLLLDAAQQLVREHGVDSLTMDALARRAGVGKGTVFRRFG 82 Query 70 SRAGLMMVLLDEDERASQQAFLFGPPPLGPDAPPLDRLIAFGRERMRFVHAHHQLL--SE 127 +R+GL+ LLD ER Q F+FGPPPLGP APPLDRL+A GR R+ + +L +E Sbjct 83 NRSGLLRALLDHSERKFQHGFMFGPPPLGPGAPPLDRLVALGRARLLDIEVEGELYRAAE 142 Query 128 ANRDPQTRHSAALSVLRTHLRVLLASAPTTGDLDAQTDALLALLDVDYVEHQLNAGGHTL 187 A + A S+L+ H+R+LL A T G+ D D LLALL V HQL+ G++ Sbjct 143 AGEAGERYVGAPYSLLKAHVRMLLREARTAGEPDLLADGLLALLSAPLVMHQLDVLGYSR 202 Query 188 QTLGDAWESLARKLCG 203 +GD WE+ R++ G Sbjct 203 TQIGDNWEAFVRRVAG 218 >gi|296140665|ref|YP_003647908.1| TetR family transcriptional regulator [Tsukamurella paurometabola DSM 20162] gi|296028799|gb|ADG79569.1| transcriptional regulator, TetR family [Tsukamurella paurometabola DSM 20162] Length=198 Score = 127 bits (320), Expect = 7e-28, Method: Compositional matrix adjust. Identities = 92/198 (47%), Positives = 119/198 (61%), Gaps = 7/198 (3%) Query 8 GDLPVFARQEPVPERGDAARNRALLLEAARRLIARSGADAITMDDVAAAAGVGKGTLFRR 67 G L A+ + P R DAARNR LL++AA+RL A G DA++MD VA AAGVGKGT+FRR Sbjct 3 GPLIPLAQPQAGPRR-DAARNRELLIDAAQRLFAEHGVDAVSMDAVAQAAGVGKGTVFRR 61 Query 68 FGSRAGLMMVLLDEDERASQQAFLFGPPPLGPDAPPLDRLIAFGRERMRFVHAHHQLL-- 125 FGSRAGL+ LLD DE QQ F+FGPPPLGP P +RL+ +G+ RM+ + H LL Sbjct 62 FGSRAGLLQALLDHDEIELQQTFMFGPPPLGPGGDPTERLVEYGKARMQMIARHGDLLRG 121 Query 126 -SEANRDPQTRHSAALSVLRTHLRVLLASAPTTGDLDAQTDALLALLDVDYVEHQLNAGG 184 +A RDP +S + +R +L +A T D AL++ L +V HQL A G Sbjct 122 AEQAARDPYDEPPWRVSAMT--VRSMLVAAGRTAQADVWAAALMSTLSPAWVLHQL-ASG 178 Query 185 HTLQTLGDAWESLARKLC 202 + +TL W R L Sbjct 179 VSQETLDSVWSEHVRLLT 196 >gi|119717584|ref|YP_924549.1| regulatory protein TetR [Nocardioides sp. JS614] gi|119538245|gb|ABL82862.1| regulatory protein, TetR [Nocardioides sp. JS614] Length=208 Score = 127 bits (319), Expect = 8e-28, Method: Compositional matrix adjust. Identities = 97/195 (50%), Positives = 120/195 (62%), Gaps = 3/195 (1%) Query 10 LPVFARQEPVPERGDAARNRALLLEAARRLIARSGADAITMDDVAAAAGVGKGTLFRRFG 69 LP+ + EP ER DAARNR LL AAR L+AR GAD +TMD VAAAAGVGKGT+FRRF Sbjct 13 LPLLS--EPPVERRDAARNREALLVAARGLVARCGADRVTMDAVAAAAGVGKGTVFRRFE 70 Query 70 SRAGLMMVLLDEDERASQQAFLFGPPPLGPDAPPLDRLIAFGRERMRFVHAHHQLLSEAN 129 SR GLM +L+ E Q + GPPPLGP A P DRL+AFGR R+ H +L+ EA Sbjct 71 SREGLMAAVLNHSETEWQGQVMSGPPPLGPGADPWDRLLAFGRTRLETTLLHAELIREAG 130 Query 130 RDPQTRHSAALSVLRTHLRVLLASAPTTGDLDAQTDALLALLDVDYVEHQLNAGGHTLQT 189 R R + A S TH+R LL TGDL ALLA L++ +E Q+ G + Sbjct 131 RA-AIRAAGAYSFTATHVRYLLHELGVTGDLPLLAVALLAPLELPILEQQVEIEGFPVDR 189 Query 190 LGDAWESLARKLCGR 204 L + W LAR++ G+ Sbjct 190 LYEGWVDLARRIVGQ 204 >gi|290962093|ref|YP_003493275.1| TetR family transcriptional regulator [Streptomyces scabiei 87.22] gi|260651619|emb|CBG74743.1| putative TetR-family transcriptional regulator [Streptomyces scabiei 87.22] Length=218 Score = 126 bits (317), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 93/187 (50%), Positives = 111/187 (60%), Gaps = 1/187 (0%) Query 17 EPVPERGDAARNRALLLEAARRLIARSGADAITMDDVAAAAGVGKGTLFRRFGSRAGLMM 76 EP R DAARNR LLE A RL A GA +TM+ VA AA VGKGT+FRRFG R GLM Sbjct 29 EPPRLRADAARNRTRLLEVAARLAADGGAAKLTMEAVATAAEVGKGTVFRRFGDRTGLMF 88 Query 77 VLLDEDERASQQAFLFGPPPLGPDAPPLDRLIAFGRERMRFVHAHHQLLSEANRDPQTRH 136 LLD ER Q AFL GPPPLGPDAPP+DRL AFG +R +AH L A D RH Sbjct 89 ALLDHHERELQAAFLTGPPPLGPDAPPVDRLRAFGVAVVRHEYAHRDLYLAAGADVSRRH 148 Query 137 SAALSVLRT-HLRVLLASAPTTGDLDAQTDALLALLDVDYVEHQLNAGGHTLQTLGDAWE 195 ++ + LR HL +LL A GD++ LL LD+ V+H + G +L+ L W Sbjct 149 TSPANQLRLGHLCMLLRRAGAAGDIELLAQTLLGFLDIGLVDHLVERRGMSLERLERGWA 208 Query 196 SLARKLC 202 L +L Sbjct 209 DLVERLV 215 >gi|300786745|ref|YP_003767036.1| TetR family transcriptional regulator [Amycolatopsis mediterranei U32] gi|299796259|gb|ADJ46634.1| TetR family transcriptional regulator [Amycolatopsis mediterranei U32] gi|340528229|gb|AEK43434.1| TetR family transcriptional regulator [Amycolatopsis mediterranei S699] Length=210 Score = 123 bits (308), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 64/102 (63%), Positives = 74/102 (73%), Gaps = 2/102 (1%) Query 9 DLPVFARQEPVPERGDAARNRALLLEAARRLIARSGADAITMDDVAAAAGVGKGTLFRRF 68 +LPV PV ER DAARNR +L+AA +L A G DA+TMDDVA AAGVGKGTL+RRF Sbjct 17 ELPVLG--APVRERADAARNRIRVLQAAEKLFAERGVDAVTMDDVAGAAGVGKGTLYRRF 74 Query 69 GSRAGLMMVLLDEDERASQQAFLFGPPPLGPDAPPLDRLIAF 110 G ++GL M LLD+ ER Q+ L GPPPLGP A P DRL AF Sbjct 75 GDKSGLAMALLDQRERELQEQILTGPPPLGPGAEPADRLGAF 116 >gi|152965537|ref|YP_001361321.1| TetR family transcriptional regulator [Kineococcus radiotolerans SRS30216] gi|151360054|gb|ABS03057.1| transcriptional regulator, TetR family [Kineococcus radiotolerans SRS30216] Length=227 Score = 122 bits (307), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 89/189 (48%), Positives = 113/189 (60%), Gaps = 4/189 (2%) Query 18 PVPERGDAARNRALLLEAARRLIARSGADAITMDDVAAAAGVGKGTLFRRFGSRAGLMMV 77 PVPER DA RNR LLL AR L+ GA ++MD +AAAAG+GKGT+FRRFGSRAGL Sbjct 35 PVPERADATRNRELLLRTARALLDEHGAAGLSMDALAAAAGLGKGTVFRRFGSRAGLFAA 94 Query 78 LLDEDERASQQAFLFGPPPLGPDAPPLDRLIAFGRERMRFVHAHHQLLSEANRDPQTRHS 137 LLDE ER Q A L+GPPPLGP A P+DRL+AFG ER+ + L+ EA+ + Sbjct 95 LLDEHERDFQAACLWGPPPLGPGADPVDRLVAFGHERLDLLARRGHLVREADAHLTRGAN 154 Query 138 AALSVLRTHLRVLLASAPTTGDLDAQTDALLALLDVDYVEHQLNA----GGHTLQTLGDA 193 A + R H+RVLL +A GD++ LLA+L+ H A + Q L Sbjct 155 APAAFARLHVRVLLQAAGVGGDVEVLAFNLLAVLEAPLARHVERAPDGPAQPSPQRLAAG 214 Query 194 WESLARKLC 202 W L R++ Sbjct 215 WTDLVRRVV 223 >gi|345000596|ref|YP_004803450.1| TetR family transcriptional regulator [Streptomyces sp. SirexAA-E] gi|344316222|gb|AEN10910.1| transcriptional regulator, TetR family [Streptomyces sp. SirexAA-E] Length=218 Score = 122 bits (306), Expect = 3e-26, Method: Compositional matrix adjust. Identities = 87/196 (45%), Positives = 114/196 (59%), Gaps = 1/196 (0%) Query 10 LPVFARQEPVPERGDAARNRALLLEAARRLIARSGADAITMDDVAAAAGVGKGTLFRRFG 69 LP+ EP R DAARNR LLLEAA RL+A GA +TM+ VAAAAGVGKGT+FRRFG Sbjct 22 LPLVTLDEPERLRADAARNRTLLLEAASRLMAGCGATNLTMESVAAAAGVGKGTVFRRFG 81 Query 70 SRAGLMMVLLDEDERASQQAFLFGPPPLGPDAPPLDRLIAFGRERMRFVHAHHQLLSEAN 129 R GL++ L+D E Q AFL GPPP+GP AP ++RL AFG +R HH+L+ + Sbjct 82 DRTGLLIALMDHREGLLQAAFLSGPPPMGPGAPAVERLHAFGPAVIRHEREHHELILASR 141 Query 130 RDPQTRHSAALSVLR-THLRVLLASAPTTGDLDAQTDALLALLDVDYVEHQLNAGGHTLQ 188 DP ++ + LR +H+ +LL A G + LL +D V H G +++ Sbjct 142 ADPLRTYAVPATRLRVSHVAMLLRQAHVAGHPELLAHTLLGSIDAALVRHLTTDRGMSIE 201 Query 189 TLGDAWESLARKLCGR 204 L W L +L R Sbjct 202 QLDQGWHDLVSRLGAR 217 >gi|311895324|dbj|BAJ27732.1| putative TetR family transcriptional regulator [Kitasatospora setae KM-6054] Length=208 Score = 122 bits (305), Expect = 5e-26, Method: Compositional matrix adjust. Identities = 86/200 (43%), Positives = 107/200 (54%), Gaps = 13/200 (6%) Query 18 PVPERGDAARNRALLLEAARRLIARSGADAITMDDVAAAAGVGKGTLFRRFGSRAGLMMV 77 P ER DAARNR LL AR +IA +G D +TMD +A AG+GKGT+FRRFG+RAG+ Sbjct 9 PPAERADAARNREALLCTARAMIAEAGVDQVTMDGLAERAGLGKGTVFRRFGTRAGIFRA 68 Query 78 LLDEDERASQQAFLFGPPPLGPDAPPLDRLIAFGRERMRFVHAHHQLLSEA-NRDPQTRH 136 LLD +E Q+ L GPPPLGP A P+DRLIA+GR R F+ + R Sbjct 69 LLDAEEYRFQEQVLAGPPPLGPGADPVDRLIAYGRARTSFLLDRRDIARAGLERKGPVPP 128 Query 137 SAALSVLRTHLRVLLASA----PTTGDLDAQ-TDAL----LALLDVDYV--EHQLNAGGH 185 H+R+LL A P L Q T AL L L D + E GG Sbjct 129 LVGAGFSHPHIRMLLGQAGLGLPDPDTLAVQLTSALDGPALLFLTADRLPPEPSGPCGGG 188 Query 186 TLQT-LGDAWESLARKLCGR 204 L T LGD+W++L +L R Sbjct 189 ELDTRLGDSWQTLVERLARR 208 >gi|325965157|ref|YP_004243063.1| TetR family transcriptional regulator [Arthrobacter phenanthrenivorans Sphe3] gi|323471244|gb|ADX74929.1| transcriptional regulator, TetR family [Arthrobacter phenanthrenivorans Sphe3] Length=202 Score = 121 bits (303), Expect = 7e-26, Method: Compositional matrix adjust. Identities = 87/183 (48%), Positives = 111/183 (61%), Gaps = 1/183 (0%) Query 21 ERGDAARNRALLLEAARRLIARSGADAITMDDVAAAAGVGKGTLFRRFGSRAGLMMVLLD 80 ER DAARNR LL AAR LI GA+ +TMD +A AGVGKGT+FRRFGSRAGLM+ LL Sbjct 17 ERSDAARNRERLLTAARELIEECGAEGLTMDRLAEQAGVGKGTVFRRFGSRAGLMLTLLS 76 Query 81 EDERASQQAFLFGPPPLGPDAPPLDRLIAFGRERMRFVHAHHQLLSEANRDPQTRHSA-A 139 E E A Q FLFGPPPLGP AP +DRLIAFG ER+ +V +L+ A + R+ A A Sbjct 77 ESEAAFQARFLFGPPPLGPGAPGMDRLIAFGTERIAYVMEFGELVLAAEHASRGRYEAPA 136 Query 140 LSVLRTHLRVLLASAPTTGDLDAQTDALLALLDVDYVEHQLNAGGHTLQTLGDAWESLAR 199 ++ H+ VLL A D +L A LD + + + A G + L +W+ L Sbjct 137 AALWHRHIEVLLRDAGFDSDPWLMASSLAATLDPERLLTLVRAHGVAPERLSASWQELVT 196 Query 200 KLC 202 ++ Sbjct 197 RVV 199 >gi|226305834|ref|YP_002765794.1| TetR family transcriptional regulator [Rhodococcus erythropolis PR4] gi|226184951|dbj|BAH33055.1| putative TetR family transcriptional regulator [Rhodococcus erythropolis PR4] Length=199 Score = 120 bits (300), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 102/199 (52%), Positives = 125/199 (63%), Gaps = 13/199 (6%) Query 6 RLGDLPVFARQEPVPERGDAARNRALLLEAARRLIARSGADAITMDDVAAAAGVGKGTLF 65 ++G +PV ERGDAARNR LLL+AA L+A G DA+TMD VA AGVGKGT+F Sbjct 8 QIGAVPV--------ERGDAARNRVLLLDAAALLVAERGVDAVTMDAVACRAGVGKGTVF 59 Query 66 RRFGSRAGLMMVLLDEDERASQQAFLFGPPPLGPDAPPLDRLIAFGRERMRFVHAHHQLL 125 RRFG+R+GLM LLD ER QQAF+FGPPPLGP APP++RLIAFGR R+ V ++L Sbjct 60 RRFGNRSGLMQALLDHTERELQQAFMFGPPPLGPGAPPIERLIAFGRARIAMVEVQGEVL 119 Query 126 SEANRDPQTRHSA---ALSVLRTHLRVLLASAPTTGDLDAQTDALLALLDVDYVEHQLNA 182 A P+ R AL + H+ LL A GDLD ALLA L+ V HQ+ Sbjct 120 RAAENAPEYRFGGPARALGI--AHVIGLLRGAGVEGDLDLLASALLAPLEASLVLHQVRD 177 Query 183 GGHTLQTLGDAWESLARKL 201 G T + L WE LAR++ Sbjct 178 LGMTTERLAAGWEDLARRV 196 >gi|229493352|ref|ZP_04387141.1| transcriptional regulator, TetR family [Rhodococcus erythropolis SK121] gi|229319668|gb|EEN85500.1| transcriptional regulator, TetR family [Rhodococcus erythropolis SK121] Length=199 Score = 120 bits (300), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 98/182 (54%), Positives = 117/182 (65%), Gaps = 1/182 (0%) Query 21 ERGDAARNRALLLEAARRLIARSGADAITMDDVAAAAGVGKGTLFRRFGSRAGLMMVLLD 80 ERGDAARNR LLL+AA L+A G DA+TMD VA AGVGKGT+FRRFG+R+GLM LLD Sbjct 15 ERGDAARNRVLLLDAAALLVAERGVDAVTMDAVACRAGVGKGTVFRRFGNRSGLMQALLD 74 Query 81 EDERASQQAFLFGPPPLGPDAPPLDRLIAFGRERMRFVHAHHQLLSEANRDPQTRHSAAL 140 ER QQAF+FGPPPLGP APP++RLIAFGR R+ V ++L A P+ R Sbjct 75 HTERELQQAFMFGPPPLGPGAPPIERLIAFGRARIAMVEVQGEVLRAAENAPEYRFGGPA 134 Query 141 SVLRT-HLRVLLASAPTTGDLDAQTDALLALLDVDYVEHQLNAGGHTLQTLGDAWESLAR 199 L H+ LL A GDLD ALLA L+ V HQ+ G T + L WE LAR Sbjct 135 RALGIAHVIGLLRGAGVEGDLDLLASALLAPLEASLVLHQVRDLGMTTERLAAGWEDLAR 194 Query 200 KL 201 ++ Sbjct 195 RV 196 >gi|297563208|ref|YP_003682182.1| TetR family transcriptional regulator [Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111] gi|296847656|gb|ADH69676.1| transcriptional regulator, TetR family [Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111] Length=205 Score = 118 bits (296), Expect = 5e-25, Method: Compositional matrix adjust. Identities = 77/192 (41%), Positives = 102/192 (54%), Gaps = 10/192 (5%) Query 21 ERGDAARNRALLLEAARRLIARSGADAITMDDVAAAAGVGKGTLFRRFGSRAGLMMVLLD 80 ER DAARNR LLE AR +IA G +TMD +A AG+GKGT+FRRFGSRAG+ + LL+ Sbjct 14 ERADAARNRERLLETARAMIAEHGTRQVTMDGLAERAGLGKGTVFRRFGSRAGIFVALLE 73 Query 81 EDERASQQAFLFGPPPLGPDAPPLDRLIAFGRERMRFVHAHHQLLSEANRDPQTRHSAAL 140 + E Q+ L GPPPLGP A P +RL+A+G R+ F+ HH + A + A+ Sbjct 74 DAEHRFQEQVLSGPPPLGPGADPAERLVAYGCARIPFLLEHHAIARAAVDRSLPVPAGAV 133 Query 141 SVLRTHLRVLLASAPTTGD----LDAQTDA-----LLALLDVDYVEHQLNAGGHTLQTLG 191 + + H+R+LL A D L Q A L+ + D V L Sbjct 134 GMTQPHIRMLLGLAGLPADRVYGLSVQLTAALEGPLVLYMSTDEVAAPPPE-PDAPNPLI 192 Query 192 DAWESLARKLCG 203 D W L +L G Sbjct 193 DGWRFLVERLLG 204 >gi|29833588|ref|NP_828222.1| TetR family transcriptional regulator [Streptomyces avermitilis MA-4680] gi|29610712|dbj|BAC74757.1| putative TetR-family transcriptional regulator [Streptomyces avermitilis MA-4680] Length=223 Score = 116 bits (290), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 90/183 (50%), Positives = 110/183 (61%), Gaps = 1/183 (0%) Query 22 RGDAARNRALLLEAARRLIARSGADAITMDDVAAAAGVGKGTLFRRFGSRAGLMMVLLDE 81 R DAARNR+ LLE A RL A GA +TM+ VA AGVGKGT+FRRFG R GL+ LLD Sbjct 33 RADAARNRSRLLEVAARLAAERGAANVTMEAVACGAGVGKGTVFRRFGDRTGLLEALLDH 92 Query 82 DERASQQAFLFGPPPLGPDAPPLDRLIAFGRERMRFVHAHHQLLSEANRDPQTRHSAALS 141 E+ Q AFL GPPPLGPDAPP++RL AFG +R H H L A+ + RH+A Sbjct 93 HEKQLQAAFLTGPPPLGPDAPPVERLRAFGSAVIRREHTHSDLYLAAHAEAARRHTAPPY 152 Query 142 VLR-THLRVLLASAPTTGDLDAQTDALLALLDVDYVEHQLNAGGHTLQTLGDAWESLARK 200 LR TH+ +LL A T GD++ LL LD V+H L G TL+ + W L + Sbjct 153 QLRLTHVCLLLRQARTEGDIELVAHTLLGYLDTILVDHLLTRRGMTLERVEAGWYDLVDR 212 Query 201 LCG 203 G Sbjct 213 CTG 215 >gi|116672560|ref|YP_833493.1| TetR family transcriptional regulator [Arthrobacter sp. FB24] gi|116612669|gb|ABK05393.1| transcriptional regulator, TetR family [Arthrobacter sp. FB24] Length=216 Score = 115 bits (288), Expect = 4e-24, Method: Compositional matrix adjust. Identities = 85/182 (47%), Positives = 110/182 (61%), Gaps = 1/182 (0%) Query 21 ERGDAARNRALLLEAARRLIARSGADAITMDDVAAAAGVGKGTLFRRFGSRAGLMMVLLD 80 ER DAARNR LLL AAR LI GAD +TMD +A AGVGKGT+FRRFGSRAGLMM LL Sbjct 17 ERSDAARNRELLLRAARELIEECGADGLTMDRLAERAGVGKGTVFRRFGSRAGLMMTLLS 76 Query 81 EDERASQQAFLFGPPPLGPDAPPLDRLIAFGRERMRFVHAHHQLLSEANRDPQTRHSAAL 140 + E Q F+FGPPPLGP APPLDRL AFG R+ +V + +L A+ R Sbjct 77 DSEAEFQGRFMFGPPPLGPGAPPLDRLAAFGAARIAYVLEYGELARAADASAYNRFDVPA 136 Query 141 SVL-RTHLRVLLASAPTTGDLDAQTDALLALLDVDYVEHQLNAGGHTLQTLGDAWESLAR 199 +VL H+ +LL +A T D +L + LD + + + + T + L ++W L Sbjct 137 AVLWHRHIEMLLRAAGVTADPWLMAMSLSSTLDPERLLYAVRVHQVTPERLNESWRELVT 196 Query 200 KL 201 ++ Sbjct 197 RV 198 >gi|119963194|ref|YP_949556.1| TetR family transcriptional regulator [Arthrobacter aurescens TC1] gi|119950053|gb|ABM08964.1| putative transcriptional regulator, TetR family [Arthrobacter aurescens TC1] Length=192 Score = 113 bits (282), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 85/184 (47%), Positives = 107/184 (59%), Gaps = 2/184 (1%) Query 21 ERGDAARNRALLLEAARRLIARSGADAITMDDVAAAAGVGKGTLFRRFGSRAGLMMVLLD 80 ER DAARNR LL AAR L+A GA+A+TMD +A A VGKGT+FRRFGSRAGLMM LL Sbjct 8 ERSDAARNRERLLNAARDLVAEFGAEALTMDALACKAQVGKGTVFRRFGSRAGLMMTLLS 67 Query 81 EDERASQQAFLFGPPPLGPDAPPLDRLIAFGRERMRFVHAHHQLLSEANRDPQTRHSA-A 139 + E Q F+FGPPPLGP A PLDRL+AFG R+ FV + +LL A + R A Sbjct 68 DSESEFQHGFMFGPPPLGPGAAPLDRLVAFGEGRIYFVLENGELLKAAGAATRNRFDVPA 127 Query 140 LSVLRTHLRVLLASAPTTGDLDAQTDALLALLDVDYVEHQLNAGGHTLQTLGDAWESLAR 199 + H+ VLL A D +L LD + + + G + L ++W L Sbjct 128 TKLSHRHMEVLLREA-GIADPWVMAMSLTYALDPERIVDDVRVRGISPTRLAESWRDLVT 186 Query 200 KLCG 203 +L G Sbjct 187 RLMG 190 Lambda K H 0.321 0.136 0.397 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 226797436674 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40