BLASTP 2.2.25+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.



Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
           15,229,318 sequences; 5,219,829,388 total letters



Query= Rv3058c

Length=216
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

gi|339299506|gb|AEJ51616.1|  TetR family transcriptional regulato...   439    2e-121
gi|15842625|ref|NP_337662.1|  TetR family transcriptional regulat...   439    2e-121
gi|148824250|ref|YP_001289004.1|  TetR family transcriptional reg...   438    2e-121
gi|15610195|ref|NP_217574.1|  TetR family transcriptional regulat...   437    6e-121
gi|340628050|ref|YP_004746502.1|  putative transcriptional regula...   434    3e-120
gi|341602982|emb|CCC65660.1|  possible transcriptional regulatory...   434    6e-120
gi|308406044|ref|ZP_07494903.2|  transcriptional regulator, tetR-...   410    9e-113
gi|118618716|ref|YP_907048.1|  TetR family transcriptional regula...   333    9e-90 
gi|118465113|ref|YP_883088.1|  TetR family transcriptional regula...   310    9e-83 
gi|240171830|ref|ZP_04750489.1|  TetR family transcriptional regu...   307    7e-82 
gi|296171146|ref|ZP_06852594.1|  TetR family transcriptional regu...   301    5e-80 
gi|254776345|ref|ZP_05217861.1|  transcriptional regulator, TetR ...   292    2e-77 
gi|41409206|ref|NP_962042.1|  hypothetical protein MAP3108c [Myco...   291    4e-77 
gi|336459248|gb|EGO38193.1|  transcriptional regulator [Mycobacte...   291    6e-77 
gi|254820774|ref|ZP_05225775.1|  transcriptional regulator, TetR ...   278    3e-73 
gi|342858091|ref|ZP_08714746.1|  TetR family transcriptional regu...   266    2e-69 
gi|333991432|ref|YP_004524046.1|  TetR family transcriptional reg...   264    7e-69 
gi|118467960|ref|YP_886640.1|  TetR family transcriptional regula...   213    1e-53 
gi|120403026|ref|YP_952855.1|  TetR family transcriptional regula...   211    7e-53 
gi|315445222|ref|YP_004078101.1|  TetR family transcriptional reg...   207    1e-51 
gi|145224893|ref|YP_001135571.1|  TetR family transcriptional reg...   206    2e-51 
gi|169630503|ref|YP_001704152.1|  TetR family transcriptional reg...   193    1e-47 
gi|108798777|ref|YP_638974.1|  TetR family transcriptional regula...   192    2e-47 
gi|111026296|ref|YP_708579.1|  TetR family transcriptional regula...  84.7    8e-15 
gi|312141723|ref|YP_004009059.1|  tetr family transcriptional reg...  82.0    6e-14 
gi|325673017|ref|ZP_08152711.1|  transcriptional regulator [Rhodo...  81.6    6e-14 
gi|302867732|ref|YP_003836369.1|  regulatory protein TetR [Microm...  75.5    5e-12 
gi|56966246|pdb|1U9O|A  Chain A, Crystal Structure Of The Transcr...  75.1    7e-12 
gi|56966245|pdb|1U9N|A  Chain A, Crystal Structure Of The Transcr...  73.9    1e-11 
gi|317457508|gb|ADV29775.1|  transcriptional regulatory repressor...  73.9    1e-11 
gi|254574835|pdb|3G1M|A  Chain A, Ethr From Mycobacterium Tubercu...  73.6    2e-11 
gi|254574836|pdb|3G1O|A  Chain A, Ethr From Mycobacterium Tubercu...  73.6    2e-11 
gi|317457510|gb|ADV29776.1|  transcriptional regulatory repressor...  73.6    2e-11 
gi|254574834|pdb|3G1L|A  Chain A, Ethr From Mycobacterium Tubercu...  73.6    2e-11 
gi|15610991|ref|NP_218372.1|  transcriptional regulatory represso...  73.6    2e-11 
gi|240168331|ref|ZP_04746990.1|  transcriptional regulatory repre...  73.2    3e-11 
gi|296165492|ref|ZP_06848024.1|  TetR family transcriptional regu...  72.0    6e-11 
gi|169628081|ref|YP_001701730.1|  TetR family transcriptional reg...  71.6    6e-11 
gi|183985374|ref|YP_001853665.1|  TetR family transcriptional reg...  70.1    2e-10 
gi|342860108|ref|ZP_08716760.1|  TetR family transcriptional regu...  69.7    3e-10 
gi|298246923|ref|ZP_06970728.1|  transcriptional regulator, TetR ...  69.3    4e-10 
gi|254773230|ref|ZP_05214746.1|  hypothetical protein MaviaA2_009...  68.6    6e-10 
gi|118620041|ref|YP_908373.1|  TetR family transcriptional regula...  68.6    6e-10 
gi|256393334|ref|YP_003114898.1|  TetR family transcriptional reg...  68.6    7e-10 
gi|118462741|ref|YP_879467.1|  TetR family transcriptional regula...  67.8    9e-10 
gi|288918443|ref|ZP_06412795.1|  transcriptional regulator, TetR ...  67.8    9e-10 
gi|41406277|ref|NP_959113.1|  hypothetical protein MAP0179c [Myco...  67.8    9e-10 
gi|336461862|gb|EGO40717.1|  transcriptional regulator [Mycobacte...  67.4    1e-09 
gi|118462781|ref|YP_884182.1|  TetR family transcriptional regula...  67.4    2e-09 
gi|119871173|ref|YP_941125.1|  TetR family transcriptional regula...  66.2    3e-09 


>gi|339299506|gb|AEJ51616.1| TetR family transcriptional regulator [Mycobacterium tuberculosis 
CCDC5180]
Length=225

 Score =  439 bits (1128),  Expect = 2e-121, Method: Compositional matrix adjust.
 Identities = 216/216 (100%), Positives = 216/216 (100%), Gaps = 0/216 (0%)

Query  1    VTSHAADEKQAAPPMRRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYF  60
            VTSHAADEKQAAPPMRRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYF
Sbjct  10   VTSHAADEKQAAPPMRRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYF  69

Query  61   YFDSKYSVLAQILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRA  120
            YFDSKYSVLAQILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRA
Sbjct  70   YFDSKYSVLAQILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRA  129

Query  121  CNAARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALM  180
            CNAARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALM
Sbjct  130  CNAARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALM  189

Query  181  LTGDALLVGPDSDAARRVRVLEQMWLNALWGGGKAP  216
            LTGDALLVGPDSDAARRVRVLEQMWLNALWGGGKAP
Sbjct  190  LTGDALLVGPDSDAARRVRVLEQMWLNALWGGGKAP  225


>gi|15842625|ref|NP_337662.1| TetR family transcriptional regulator [Mycobacterium tuberculosis 
CDC1551]
 gi|254233688|ref|ZP_04927013.1| hypothetical protein TBCG_02994 [Mycobacterium tuberculosis C]
 gi|13882940|gb|AAK47476.1| transcriptional regulator, TetR family [Mycobacterium tuberculosis 
CDC1551]
 gi|124599217|gb|EAY58321.1| hypothetical protein TBCG_02994 [Mycobacterium tuberculosis C]
 gi|339295893|gb|AEJ48004.1| TetR family transcriptional regulator [Mycobacterium tuberculosis 
CCDC5079]
Length=237

 Score =  439 bits (1128),  Expect = 2e-121, Method: Compositional matrix adjust.
 Identities = 216/216 (100%), Positives = 216/216 (100%), Gaps = 0/216 (0%)

Query  1    VTSHAADEKQAAPPMRRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYF  60
            VTSHAADEKQAAPPMRRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYF
Sbjct  22   VTSHAADEKQAAPPMRRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYF  81

Query  61   YFDSKYSVLAQILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRA  120
            YFDSKYSVLAQILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRA
Sbjct  82   YFDSKYSVLAQILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRA  141

Query  121  CNAARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALM  180
            CNAARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALM
Sbjct  142  CNAARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALM  201

Query  181  LTGDALLVGPDSDAARRVRVLEQMWLNALWGGGKAP  216
            LTGDALLVGPDSDAARRVRVLEQMWLNALWGGGKAP
Sbjct  202  LTGDALLVGPDSDAARRVRVLEQMWLNALWGGGKAP  237


>gi|148824250|ref|YP_001289004.1| TetR family transcriptional regulator [Mycobacterium tuberculosis 
F11]
 gi|167969661|ref|ZP_02551938.1| transcriptional regulator, TetR family protein [Mycobacterium 
tuberculosis H37Ra]
 gi|253797843|ref|YP_003030844.1| transcriptional regulator, tetR-family [Mycobacterium tuberculosis 
KZN 1435]
 9 more sequence titles
 Length=226

 Score =  438 bits (1127),  Expect = 2e-121, Method: Compositional matrix adjust.
 Identities = 216/216 (100%), Positives = 216/216 (100%), Gaps = 0/216 (0%)

Query  1    VTSHAADEKQAAPPMRRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYF  60
            VTSHAADEKQAAPPMRRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYF
Sbjct  11   VTSHAADEKQAAPPMRRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYF  70

Query  61   YFDSKYSVLAQILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRA  120
            YFDSKYSVLAQILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRA
Sbjct  71   YFDSKYSVLAQILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRA  130

Query  121  CNAARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALM  180
            CNAARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALM
Sbjct  131  CNAARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALM  190

Query  181  LTGDALLVGPDSDAARRVRVLEQMWLNALWGGGKAP  216
            LTGDALLVGPDSDAARRVRVLEQMWLNALWGGGKAP
Sbjct  191  LTGDALLVGPDSDAARRVRVLEQMWLNALWGGGKAP  226


>gi|15610195|ref|NP_217574.1| TetR family transcriptional regulator [Mycobacterium tuberculosis 
H37Rv]
 gi|31794236|ref|NP_856729.1| TetR family transcriptional regulator [Mycobacterium bovis AF2122/97]
 gi|121638943|ref|YP_979167.1| TetR family transcriptional regulator [Mycobacterium bovis BCG 
str. Pasteur 1173P2]
 54 more sequence titles
 Length=216

 Score =  437 bits (1123),  Expect = 6e-121, Method: Compositional matrix adjust.
 Identities = 215/216 (99%), Positives = 216/216 (100%), Gaps = 0/216 (0%)

Query  1    VTSHAADEKQAAPPMRRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYF  60
            +TSHAADEKQAAPPMRRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYF
Sbjct  1    MTSHAADEKQAAPPMRRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYF  60

Query  61   YFDSKYSVLAQILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRA  120
            YFDSKYSVLAQILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRA
Sbjct  61   YFDSKYSVLAQILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRA  120

Query  121  CNAARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALM  180
            CNAARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALM
Sbjct  121  CNAARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALM  180

Query  181  LTGDALLVGPDSDAARRVRVLEQMWLNALWGGGKAP  216
            LTGDALLVGPDSDAARRVRVLEQMWLNALWGGGKAP
Sbjct  181  LTGDALLVGPDSDAARRVRVLEQMWLNALWGGGKAP  216


>gi|340628050|ref|YP_004746502.1| putative transcriptional regulatory protein [Mycobacterium canettii 
CIPT 140010059]
 gi|340006240|emb|CCC45414.1| putative transcriptional regulatory protein (probably TETR-family) 
[Mycobacterium canettii CIPT 140010059]
Length=216

 Score =  434 bits (1117),  Expect = 3e-120, Method: Compositional matrix adjust.
 Identities = 214/216 (99%), Positives = 215/216 (99%), Gaps = 0/216 (0%)

Query  1    VTSHAADEKQAAPPMRRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYF  60
            +TSHAADEKQAAPPMRRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYF
Sbjct  1    MTSHAADEKQAAPPMRRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYF  60

Query  61   YFDSKYSVLAQILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRA  120
            YFDSKYSVLAQILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRA
Sbjct  61   YFDSKYSVLAQILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRA  120

Query  121  CNAARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALM  180
            CNAARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALM
Sbjct  121  CNAARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALM  180

Query  181  LTGDALLVGPDSDAARRVRVLEQMWLNALWGGGKAP  216
            LTGDALLVGPDSD ARRVRVLEQMWLNALWGGGKAP
Sbjct  181  LTGDALLVGPDSDPARRVRVLEQMWLNALWGGGKAP  216


>gi|341602982|emb|CCC65660.1| possible transcriptional regulatory protein (probably tetR-family) 
[Mycobacterium bovis BCG str. Moreau RDJ]
Length=216

 Score =  434 bits (1115),  Expect = 6e-120, Method: Compositional matrix adjust.
 Identities = 214/216 (99%), Positives = 215/216 (99%), Gaps = 0/216 (0%)

Query  1    VTSHAADEKQAAPPMRRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYF  60
            +TSHAADEKQAAPPMRRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYF
Sbjct  1    MTSHAADEKQAAPPMRRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYF  60

Query  61   YFDSKYSVLAQILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRA  120
            YFDSKYSVLAQILAEATEELEEASQHFSARQP ESPEQFVNRMIGSVAAVYANNDPVLRA
Sbjct  61   YFDSKYSVLAQILAEATEELEEASQHFSARQPWESPEQFVNRMIGSVAAVYANNDPVLRA  120

Query  121  CNAARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALM  180
            CNAARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALM
Sbjct  121  CNAARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALM  180

Query  181  LTGDALLVGPDSDAARRVRVLEQMWLNALWGGGKAP  216
            LTGDALLVGPDSDAARRVRVLEQMWLNALWGGGKAP
Sbjct  181  LTGDALLVGPDSDAARRVRVLEQMWLNALWGGGKAP  216


>gi|308406044|ref|ZP_07494903.2| transcriptional regulator, tetR-family [Mycobacterium tuberculosis 
SUMu012]
 gi|308364711|gb|EFP53562.1| transcriptional regulator, tetR-family [Mycobacterium tuberculosis 
SUMu012]
 gi|323718290|gb|EGB27468.1| transcriptional regulator [Mycobacterium tuberculosis CDC1551A]
Length=202

 Score =  410 bits (1053),  Expect = 9e-113, Method: Compositional matrix adjust.
 Identities = 202/202 (100%), Positives = 202/202 (100%), Gaps = 0/202 (0%)

Query  15   MRRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYFYFDSKYSVLAQILA  74
            MRRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYFYFDSKYSVLAQILA
Sbjct  1    MRRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYFYFDSKYSVLAQILA  60

Query  75   EATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRACNAARQSDMEIRDI  134
            EATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRACNAARQSDMEIRDI
Sbjct  61   EATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRACNAARQSDMEIRDI  120

Query  135  LERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALMLTGDALLVGPDSDA  194
            LERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALMLTGDALLVGPDSDA
Sbjct  121  LERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALMLTGDALLVGPDSDA  180

Query  195  ARRVRVLEQMWLNALWGGGKAP  216
            ARRVRVLEQMWLNALWGGGKAP
Sbjct  181  ARRVRVLEQMWLNALWGGGKAP  202


>gi|118618716|ref|YP_907048.1| TetR family transcriptional regulator [Mycobacterium ulcerans 
Agy99]
 gi|183981649|ref|YP_001849940.1| TetR family transcriptional regulator [Mycobacterium marinum 
M]
 gi|118570826|gb|ABL05577.1| transcriptional regulatory protein (TetR- family) [Mycobacterium 
ulcerans Agy99]
 gi|183174975|gb|ACC40085.1| transcriptional regulatory protein (TetR- family) [Mycobacterium 
marinum M]
Length=217

 Score =  333 bits (854),  Expect = 9e-90, Method: Compositional matrix adjust.
 Identities = 159/212 (75%), Positives = 183/212 (87%), Gaps = 0/212 (0%)

Query  1    VTSHAADEKQAAPPMRRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYF  60
            V   AADEKQ  P +RRRGD+ RQAIL+A RELLEE PFAELSV  IS RAGVARSGFYF
Sbjct  2    VNGQAADEKQRGPTLRRRGDKQRQAILQAVRELLEERPFAELSVATISNRAGVARSGFYF  61

Query  61   YFDSKYSVLAQILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRA  120
            YFDSKYSVLAQ++AEA EELEE +Q+F+ RQPGESP++F  RM+GS A VY +NDPV+ A
Sbjct  62   YFDSKYSVLAQLMAEAVEELEERTQYFAPRQPGESPQEFAKRMVGSAAIVYTHNDPVMMA  121

Query  121  CNAARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALM  180
            CNAAR +D+EIRDIL++QF V+LRE +GV +AE++AGTA+PISEDLPTL+RTL ATTALM
Sbjct  122  CNAARHTDIEIRDILDQQFDVVLREIVGVIDAEMRAGTANPISEDLPTLIRTLTATTALM  181

Query  181  LTGDALLVGPDSDAARRVRVLEQMWLNALWGG  212
            LTGDALLVG DSD  RRVRVLEQMWLNALWGG
Sbjct  182  LTGDALLVGRDSDLERRVRVLEQMWLNALWGG  213


>gi|118465113|ref|YP_883088.1| TetR family transcriptional regulator [Mycobacterium avium 104]
 gi|118166400|gb|ABK67297.1| transcriptional regulator, TetR family protein [Mycobacterium 
avium 104]
Length=211

 Score =  310 bits (794),  Expect = 9e-83, Method: Compositional matrix adjust.
 Identities = 147/212 (70%), Positives = 180/212 (85%), Gaps = 3/212 (1%)

Query  1    VTSHAADEKQAAPPMRRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYF  60
            +TSH A+ +   P  RRRGD+ RQAIL A RELL+E PFAELSV  ISLRAGVARSGFYF
Sbjct  1    MTSHPANPE---PGARRRGDKQRQAILAAVRELLQEKPFAELSVSTISLRAGVARSGFYF  57

Query  61   YFDSKYSVLAQILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRA  120
            YFDSKY+VLAQ++AEATEELE+ +Q+F+ RQPGESPEQF  RM+GS AAVYA+NDPV+ A
Sbjct  58   YFDSKYAVLAQLMAEATEELEQLTQYFAPRQPGESPEQFAKRMVGSAAAVYAHNDPVMTA  117

Query  121  CNAARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALM  180
            CN AR +D+EIR+++++QF+V+L + +G+ EAE+KAGTA PIS+DLPTL+RTLA TTALM
Sbjct  118  CNEARHTDVEIRNLMDQQFEVVLAQIVGIVEAEMKAGTARPISDDLPTLIRTLAGTTALM  177

Query  181  LTGDALLVGPDSDAARRVRVLEQMWLNALWGG  212
            LTGD +L GPDSD  RRV VLEQ+WL+ALW G
Sbjct  178  LTGDPVLTGPDSDRDRRVAVLEQLWLHALWAG  209


>gi|240171830|ref|ZP_04750489.1| TetR family transcriptional regulator [Mycobacterium kansasii 
ATCC 12478]
Length=215

 Score =  307 bits (786),  Expect = 7e-82, Method: Compositional matrix adjust.
 Identities = 157/212 (75%), Positives = 184/212 (87%), Gaps = 1/212 (0%)

Query  1    VTSHAADEKQAAPPMRRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYF  60
            ++ HA D+ QA P +RRRGD+HRQAIL+A RELL+E PFAELSV  IS RAGVARSGFYF
Sbjct  1    MSEHAPDQ-QAVPALRRRGDKHRQAILQAVRELLQERPFAELSVSTISNRAGVARSGFYF  59

Query  61   YFDSKYSVLAQILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRA  120
            YFDSKY+VLAQILAEA EELEE + +F+ RQPGESP+QF  RM+GS A VYA+NDPV+ A
Sbjct  60   YFDSKYAVLAQILAEAAEELEELTHYFAPRQPGESPQQFAKRMVGSAAVVYAHNDPVIVA  119

Query  121  CNAARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALM  180
            CNAAR +D+EIR+ILE+QF V+LRE +GV EAE++AGTA+PIS+DLPTL+RTLA TTAL+
Sbjct  120  CNAARHTDIEIREILEQQFDVVLREIVGVVEAEMRAGTANPISDDLPTLIRTLAGTTALV  179

Query  181  LTGDALLVGPDSDAARRVRVLEQMWLNALWGG  212
            LTGD LLVG DSD  RRVRVLEQMWLNALWGG
Sbjct  180  LTGDPLLVGRDSDPDRRVRVLEQMWLNALWGG  211


>gi|296171146|ref|ZP_06852594.1| TetR family transcriptional regulator [Mycobacterium parascrofulaceum 
ATCC BAA-614]
 gi|295894282|gb|EFG74037.1| TetR family transcriptional regulator [Mycobacterium parascrofulaceum 
ATCC BAA-614]
Length=220

 Score =  301 bits (771),  Expect = 5e-80, Method: Compositional matrix adjust.
 Identities = 143/212 (68%), Positives = 178/212 (84%), Gaps = 3/212 (1%)

Query  1    VTSHAADEKQAAPPMRRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYF  60
            ++SH A  +   P  +RRGD+ RQAIL+A RELL+E PFAELSV  ISLRAGVARSGFYF
Sbjct  10   MSSHPATPE---PGGQRRGDKQRQAILQAVRELLQEKPFAELSVSTISLRAGVARSGFYF  66

Query  61   YFDSKYSVLAQILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRA  120
            YFDSKY+VLAQ++AEA  ELEE +Q F+ R+PGESPEQF  RM+GS AAVYA+NDPV+ A
Sbjct  67   YFDSKYAVLAQLMAEAARELEELTQDFAPREPGESPEQFAQRMVGSAAAVYAHNDPVMTA  126

Query  121  CNAARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALM  180
            CN AR +D+EIR+++++QF+V+L + + + EAE+KAGTAHPIS+DLPTL+RTLA TTALM
Sbjct  127  CNEARNTDVEIRNLMDQQFEVVLGQIVAIVEAEMKAGTAHPISDDLPTLIRTLAGTTALM  186

Query  181  LTGDALLVGPDSDAARRVRVLEQMWLNALWGG  212
            LTGD +L G DSD  RRVRVLE++WL+ALWGG
Sbjct  187  LTGDPILAGRDSDLDRRVRVLERLWLHALWGG  218


>gi|254776345|ref|ZP_05217861.1| transcriptional regulator, TetR family protein [Mycobacterium 
avium subsp. avium ATCC 25291]
Length=211

 Score =  292 bits (747),  Expect = 2e-77, Method: Compositional matrix adjust.
 Identities = 148/212 (70%), Positives = 180/212 (85%), Gaps = 3/212 (1%)

Query  1    VTSHAADEKQAAPPMRRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYF  60
            +TSH A+ +   P  RRRGD+ RQAIL A RELL+E PFAELSV  ISLRAGVARSGFYF
Sbjct  1    MTSHPANPE---PGARRRGDKQRQAILAAVRELLQEKPFAELSVSTISLRAGVARSGFYF  57

Query  61   YFDSKYSVLAQILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRA  120
            YFDSKY+VLAQ++AEATEELEE +Q+F+ RQPGESPEQF  RM+GS AAVYA+NDPV+ A
Sbjct  58   YFDSKYAVLAQLMAEATEELEELTQYFAPRQPGESPEQFAKRMVGSAAAVYAHNDPVMTA  117

Query  121  CNAARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALM  180
            CN AR +D+EIR+++++QF+V+L + +G+ EAE+KAGTA PIS+DLPTL+RTLA TTALM
Sbjct  118  CNEARHTDVEIRNLMDQQFEVVLAQIVGIVEAEMKAGTARPISDDLPTLIRTLAGTTALM  177

Query  181  LTGDALLVGPDSDAARRVRVLEQMWLNALWGG  212
            LTGD +L GPDSD  RRV VLEQ+WL+ALW G
Sbjct  178  LTGDPVLTGPDSDRDRRVAVLEQLWLHALWAG  209


>gi|41409206|ref|NP_962042.1| hypothetical protein MAP3108c [Mycobacterium avium subsp. paratuberculosis 
K-10]
 gi|41398026|gb|AAS05656.1| hypothetical protein MAP_3108c [Mycobacterium avium subsp. paratuberculosis 
K-10]
Length=217

 Score =  291 bits (746),  Expect = 4e-77, Method: Compositional matrix adjust.
 Identities = 148/212 (70%), Positives = 179/212 (85%), Gaps = 3/212 (1%)

Query  1    VTSHAADEKQAAPPMRRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYF  60
            VTSH A+ +   P  RRRGD+ RQAIL   RELL+E PFAELSV  ISLRAGVARSGFYF
Sbjct  7    VTSHPANPE---PGARRRGDKQRQAILAVVRELLQEKPFAELSVSTISLRAGVARSGFYF  63

Query  61   YFDSKYSVLAQILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRA  120
            YFDSKY+VLAQ++AEATEELEE +Q+F+ RQPGESPEQF  RM+GS AAVYA+NDPV+ A
Sbjct  64   YFDSKYAVLAQLMAEATEELEELTQYFAPRQPGESPEQFAKRMVGSAAAVYAHNDPVMTA  123

Query  121  CNAARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALM  180
            CN AR +D+EIR+++++QF+V+L + +G+ EAE+KAGTA PIS+DLPTL+RTLA TTALM
Sbjct  124  CNEARHTDVEIRNLMDQQFEVVLAQIVGIVEAEMKAGTARPISDDLPTLIRTLAGTTALM  183

Query  181  LTGDALLVGPDSDAARRVRVLEQMWLNALWGG  212
            LTGD +L GPDSD  RRV VLEQ+WL+ALW G
Sbjct  184  LTGDPVLTGPDSDRDRRVAVLEQLWLHALWAG  215


>gi|336459248|gb|EGO38193.1| transcriptional regulator [Mycobacterium avium subsp. paratuberculosis 
S397]
Length=211

 Score =  291 bits (744),  Expect = 6e-77, Method: Compositional matrix adjust.
 Identities = 147/212 (70%), Positives = 179/212 (85%), Gaps = 3/212 (1%)

Query  1    VTSHAADEKQAAPPMRRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYF  60
            +TSH A+ +   P  RRRGD+ RQ IL A RELL+E PFAELSV  ISLRAGVARSGFYF
Sbjct  1    MTSHPANPE---PGARRRGDKQRQVILAAVRELLQEKPFAELSVSTISLRAGVARSGFYF  57

Query  61   YFDSKYSVLAQILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRA  120
            YFDSKY+VLAQ++AEATEELEE +Q+F+ RQPGESPEQF  RM+GS AAVYA+NDPV+ A
Sbjct  58   YFDSKYAVLAQLMAEATEELEELTQYFAPRQPGESPEQFAKRMVGSAAAVYAHNDPVMTA  117

Query  121  CNAARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALM  180
            CN AR +D+EIR+++++QF+V+L + +G+ EAE+KAGTA PIS+DLPTL+RTLA TTALM
Sbjct  118  CNEARHTDVEIRNLMDQQFEVVLAQIVGIVEAEMKAGTARPISDDLPTLIRTLAGTTALM  177

Query  181  LTGDALLVGPDSDAARRVRVLEQMWLNALWGG  212
            LTGD +L GPDSD  RRV VLEQ+WL+ALW G
Sbjct  178  LTGDPVLTGPDSDRDRRVAVLEQLWLHALWAG  209


>gi|254820774|ref|ZP_05225775.1| transcriptional regulator, TetR family protein [Mycobacterium 
intracellulare ATCC 13950]
Length=211

 Score =  278 bits (712),  Expect = 3e-73, Method: Compositional matrix adjust.
 Identities = 142/212 (67%), Positives = 176/212 (84%), Gaps = 3/212 (1%)

Query  1    VTSHAADEKQAAPPMRRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYF  60
            ++SH A+ +   P  RRRGD+ RQAI+ A RELL+E PFAELSV  ISLRAGVARSGFYF
Sbjct  1    MSSHPANPE---PGARRRGDKQRQAIVEAVRELLQEKPFAELSVSTISLRAGVARSGFYF  57

Query  61   YFDSKYSVLAQILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRA  120
            YFDSKY+VLAQ++AEATEELEE +Q+F+ RQ GESPE+F  RM+GS AAVY +NDPV+ A
Sbjct  58   YFDSKYAVLAQLMAEATEELEELTQYFAPRQAGESPEEFAKRMVGSAAAVYEHNDPVVTA  117

Query  121  CNAARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALM  180
            CN AR +D+EIRD+L++QF+V+L + + + EAE+KAGTA PIS+DLPTL+RTL  TTAL+
Sbjct  118  CNEARHTDVEIRDLLDQQFEVVLAQIVAIVEAEMKAGTARPISDDLPTLIRTLTGTTALV  177

Query  181  LTGDALLVGPDSDAARRVRVLEQMWLNALWGG  212
            LTGD +L G DSD  RRVRVLEQ+WL+ALW G
Sbjct  178  LTGDPVLTGSDSDRDRRVRVLEQLWLHALWSG  209


>gi|342858091|ref|ZP_08714746.1| TetR family transcriptional regulator [Mycobacterium colombiense 
CECT 3035]
 gi|342133795|gb|EGT86975.1| TetR family transcriptional regulator [Mycobacterium colombiense 
CECT 3035]
Length=211

 Score =  266 bits (679),  Expect = 2e-69, Method: Compositional matrix adjust.
 Identities = 146/212 (69%), Positives = 178/212 (84%), Gaps = 3/212 (1%)

Query  1    VTSHAADEKQAAPPMRRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYF  60
            +TSH A  +   P  RRRGD+ RQAIL+A RELL+E PFAELSV  ISLRAGVARSGFYF
Sbjct  1    MTSHPATPE---PGARRRGDKQRQAILQAVRELLQEKPFAELSVSTISLRAGVARSGFYF  57

Query  61   YFDSKYSVLAQILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRA  120
            YFDSKY+VLAQ++AEA EELEE +++F+ RQ GESPEQF  RM+GS AAVYA+NDPV+ A
Sbjct  58   YFDSKYAVLAQLMAEAAEELEELTEYFAPRQAGESPEQFAKRMVGSAAAVYAHNDPVVTA  117

Query  121  CNAARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALM  180
            CN AR +D+EIRD+L++QF+V+L + +G+ EAE+KAGTA PIS+DLPTL+RTLA TTAL+
Sbjct  118  CNEARNTDVEIRDLLDQQFEVVLGQIVGIVEAEMKAGTATPISDDLPTLIRTLAGTTALV  177

Query  181  LTGDALLVGPDSDAARRVRVLEQMWLNALWGG  212
            LTGD +L G DSD  RRVRVLEQ+WL+ALW G
Sbjct  178  LTGDPILTGRDSDRDRRVRVLEQLWLHALWAG  209


>gi|333991432|ref|YP_004524046.1| TetR family transcriptional regulator [Mycobacterium sp. JDM601]
 gi|333487400|gb|AEF36792.1| TetR family transcriptional regulator [Mycobacterium sp. JDM601]
Length=218

 Score =  264 bits (674),  Expect = 7e-69, Method: Compositional matrix adjust.
 Identities = 127/199 (64%), Positives = 152/199 (77%), Gaps = 0/199 (0%)

Query  17   RRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYFYFDSKYSVLAQILAEA  76
            RRGD+ RQAI++A RELLEE PFAELSV  IS RAGVARSGFYFYFDSKY+VLA ILAEA
Sbjct  18   RRGDKQRQAIVQAVRELLEEKPFAELSVSTISDRAGVARSGFYFYFDSKYAVLAHILAEA  77

Query  77   TEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRACNAARQSDMEIRDILE  136
            ++ELEE +Q+F+ R   ESP  F  RM+GS AAV+A+NDPV+ ACN AR SD EIR++L+
Sbjct  78   SQELEELTQYFAPRGAEESPAAFAERMVGSAAAVFAHNDPVMSACNMARNSDAEIRELLD  137

Query  137  RQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALMLTGDALLVGPDSDAAR  196
             Q   ++ + +GV   E+ AGTA PISED+P LVRTLAATT  ML+GD   +G D D  R
Sbjct  138  AQIDAVIHQIVGVVNDEIAAGTADPISEDIPALVRTLAATTGYMLSGDTAFLGTDGDVGR  197

Query  197  RVRVLEQMWLNALWGGGKA  215
             VRVLE +WL ALWGG  A
Sbjct  198  GVRVLEALWLTALWGGDAA  216


>gi|118467960|ref|YP_886640.1| TetR family transcriptional regulator [Mycobacterium smegmatis 
str. MC2 155]
 gi|118473528|ref|YP_885411.1| TetR family transcriptional regulator [Mycobacterium smegmatis 
str. MC2 155]
 gi|118169247|gb|ABK70143.1| transcriptional regulator, TetR family protein [Mycobacterium 
smegmatis str. MC2 155]
 gi|118174815|gb|ABK75711.1| transcriptional regulator, TetR family protein [Mycobacterium 
smegmatis str. MC2 155]
Length=219

 Score =  213 bits (543),  Expect = 1e-53, Method: Compositional matrix adjust.
 Identities = 117/210 (56%), Positives = 147/210 (70%), Gaps = 3/210 (1%)

Query  3    SHAADEKQAAPPMRRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYFYF  62
            S+ +    AA   R RGDR R+AI+ A RELLEE PFA++SV  IS RAGVARSGFYFYF
Sbjct  10   SNGSAGATAAQARRSRGDRQREAIVAAVRELLEEQPFADISVSTISERAGVARSGFYFYF  69

Query  63   DSKYSVLAQILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRACN  122
            DSKY+VLA ILAEA EEL+  + +F+ R   ESP  F  RM+GS AAVYA NDPV+ AC 
Sbjct  70   DSKYAVLAVILAEAMEELDALTHNFAPRGENESPAAFAKRMVGSAAAVYATNDPVMSACT  129

Query  123  AARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALMLT  182
             A+ +D +IRDI+       + + +GV E +     A PIS+DLP LVRTL ATTA+ L+
Sbjct  130  VAQNTDAQIRDIMNDFEDATIAKIVGVIEQDTG---ARPISDDLPALVRTLTATTAMTLS  186

Query  183  GDALLVGPDSDAARRVRVLEQMWLNALWGG  212
             DA  VG D+D AR V ++E++WL+ALWGG
Sbjct  187  RDAGFVGRDADPARAVEIVERLWLSALWGG  216


>gi|120403026|ref|YP_952855.1| TetR family transcriptional regulator [Mycobacterium vanbaalenii 
PYR-1]
 gi|119955844|gb|ABM12849.1| transcriptional regulator, TetR family [Mycobacterium vanbaalenii 
PYR-1]
Length=213

 Score =  211 bits (537),  Expect = 7e-53, Method: Compositional matrix adjust.
 Identities = 106/197 (54%), Positives = 139/197 (71%), Gaps = 3/197 (1%)

Query  16   RRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYFYFDSKYSVLAQILAE  75
            R RGDR R AI+ A RELL+E  FA+LSV  IS RAGVARSGFYFYFDSKY+VLA I+AE
Sbjct  12   RSRGDRQRDAIIAAVRELLQERAFADLSVSTISERAGVARSGFYFYFDSKYAVLAVIVAE  71

Query  76   ATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRACNAARQSDMEIRDIL  135
            A  EL++ +  F+ R+PGESP  F  RM+G  A VYA NDP++ ACN AR +D EIR+I+
Sbjct  72   AMAELDQLTHDFAPREPGESPSDFAKRMVGYAATVYARNDPIMGACNLARNTDAEIREIM  131

Query  136  ERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALMLTGDALLVGPDSDAA  195
            +  FQ  + + I   +   +   A P+S+DLP LVRTL A T++ L  D+  VG  +D A
Sbjct  132  D-DFQDSVIDKI--VDLVGRDSGARPVSQDLPALVRTLIAMTSMTLAHDSAFVGRGADPA  188

Query  196  RRVRVLEQMWLNALWGG  212
            R V ++E++WL++LWGG
Sbjct  189  RAVEIVERLWLSSLWGG  205


>gi|315445222|ref|YP_004078101.1| TetR family transcriptional regulator [Mycobacterium sp. Spyr1]
 gi|315263525|gb|ADU00267.1| transcriptional regulator, TetR family [Mycobacterium sp. Spyr1]
Length=212

 Score =  207 bits (526),  Expect = 1e-51, Method: Compositional matrix adjust.
 Identities = 102/197 (52%), Positives = 136/197 (70%), Gaps = 3/197 (1%)

Query  16   RRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYFYFDSKYSVLAQILAE  75
            R RGDR R AI+ A RELL E PFAELSV  IS RAGVARSGFYFYFDSKY+VLA I+AE
Sbjct  18   RSRGDRQRDAIVTAVRELLHERPFAELSVSTISERAGVARSGFYFYFDSKYAVLAVIIAE  77

Query  76   ATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRACNAARQSDMEIRDIL  135
            A  EL++ +  F+ R   ESP +F  RM+G  A V+A+NDP++RACN AR +D +IR+I+
Sbjct  78   AMAELDQLTHSFAPRDEAESPSEFAKRMVGYAAIVFASNDPIMRACNLARSTDAQIREIM  137

Query  136  ERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALMLTGDALLVGPDSDAA  195
            +     ++ + +G+     +   A PIS+DLP LVR + A T+  L  D+  VG D D A
Sbjct  138  DDFQNTVVEKIVGLVG---RDAGARPISDDLPALVRVMIAVTSSTLAHDSAFVGRDGDPA  194

Query  196  RRVRVLEQMWLNALWGG  212
            R + V+E++W ++LWGG
Sbjct  195  RALAVVERLWESSLWGG  211


>gi|145224893|ref|YP_001135571.1| TetR family transcriptional regulator [Mycobacterium gilvum PYR-GCK]
 gi|145217379|gb|ABP46783.1| transcriptional regulator, TetR family [Mycobacterium gilvum 
PYR-GCK]
Length=212

 Score =  206 bits (525),  Expect = 2e-51, Method: Compositional matrix adjust.
 Identities = 102/197 (52%), Positives = 135/197 (69%), Gaps = 3/197 (1%)

Query  16   RRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYFYFDSKYSVLAQILAE  75
            R RGDR R AI+ A RELL E PFAELSV  IS RAGVARSGFYFYFDSKY+VLA I+AE
Sbjct  18   RSRGDRQRDAIVTAVRELLHERPFAELSVSTISERAGVARSGFYFYFDSKYAVLAVIIAE  77

Query  76   ATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRACNAARQSDMEIRDIL  135
            A  EL++ +  F  R   ESP +F  RM+G  A V+A+NDP++RACN AR +D +IR+I+
Sbjct  78   AMAELDQLTHSFGPRDEAESPSEFAKRMVGYAAIVFASNDPIMRACNLARSTDAQIREIM  137

Query  136  ERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALMLTGDALLVGPDSDAA  195
            +     ++ + +G+     +   A PIS+DLP LVR + A T+  L  D+  VG D D A
Sbjct  138  DDFQNTVVEKIVGLVG---RDAGARPISDDLPALVRVMIAVTSSTLAHDSAFVGRDGDPA  194

Query  196  RRVRVLEQMWLNALWGG  212
            R + V+E++W ++LWGG
Sbjct  195  RALAVVERLWESSLWGG  211


>gi|169630503|ref|YP_001704152.1| TetR family transcriptional regulator [Mycobacterium abscessus 
ATCC 19977]
 gi|169242470|emb|CAM63498.1| Putative transcriptional regulator, TetR family [Mycobacterium 
abscessus]
Length=207

 Score =  193 bits (491),  Expect = 1e-47, Method: Compositional matrix adjust.
 Identities = 98/195 (51%), Positives = 135/195 (70%), Gaps = 1/195 (0%)

Query  18   RGDRHRQAILRAARELLEET-PFAELSVRAISLRAGVARSGFYFYFDSKYSVLAQILAEA  76
            RGDR R AI+ A  EL+ E   FA+LSV AIS RAGV RSGFYFYFDSKYSVLAQ++ +A
Sbjct  12   RGDRQRDAIMTAVAELIAENHSFADLSVSAISERAGVGRSGFYFYFDSKYSVLAQMVGDA  71

Query  77   TEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRACNAARQSDMEIRDILE  136
              EL+E + +F+ R   E+PEQF +RM+GS AA +A+NDP+++AC  AR +D  I  +L+
Sbjct  72   FAELDELTHYFAPRGEEETPEQFAHRMVGSAAASFAHNDPLMKACQEARITDPTIAGLLD  131

Query  137  RQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALMLTGDALLVGPDSDAAR  196
                V++ + + + E EVK   A PIS+DLP LVR+L A TA  ++GD+  VG ++D AR
Sbjct  132  DLTDVVIEKILKIAETEVKERGAQPISDDLPALVRSLVALTASTVSGDSSFVGRNTDPAR  191

Query  197  RVRVLEQMWLNALWG  211
             +  +E +W  +L G
Sbjct  192  AIATVETLWRVSLLG  206


>gi|108798777|ref|YP_638974.1| TetR family transcriptional regulator [Mycobacterium sp. MCS]
 gi|119867895|ref|YP_937847.1| TetR family transcriptional regulator [Mycobacterium sp. KMS]
 gi|126434378|ref|YP_001070069.1| TetR family transcriptional regulator [Mycobacterium sp. JLS]
 gi|108769196|gb|ABG07918.1| transcriptional regulator, TetR family [Mycobacterium sp. MCS]
 gi|119693984|gb|ABL91057.1| transcriptional regulator, TetR family [Mycobacterium sp. KMS]
 gi|126234178|gb|ABN97578.1| transcriptional regulator, TetR family [Mycobacterium sp. JLS]
Length=211

 Score =  192 bits (489),  Expect = 2e-47, Method: Compositional matrix adjust.
 Identities = 108/205 (53%), Positives = 143/205 (70%), Gaps = 4/205 (1%)

Query  9    KQAAPPMRR-RGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYFYFDSKYS  67
            + A P +RR RGDR R AI+ A RELL+E PFA+LSV  IS RAGVARSGFYFYFDSKY+
Sbjct  4    ESATPEIRRSRGDRQRDAIVAAVRELLQEQPFADLSVSTISERAGVARSGFYFYFDSKYA  63

Query  68   VLAQILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRACNAARQS  127
            VLA I+A+A  EL++ +  F+ R   ESP  F  RM+G  AAV+A+N+P++RA   AR +
Sbjct  64   VLAVIVADAMAELDKLTHDFAPRDADESPATFARRMVGYAAAVFASNNPIMRATTLARNT  123

Query  128  DMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALMLTGDALL  187
            D +IR+I+      ++ + +G+   +     A PIS+DLP LVRTL ATTAL L+ D+  
Sbjct  124  DAQIREIMNDFEDTVIDKIVGLVRQD---DGARPISDDLPALVRTLTATTALTLSHDSGF  180

Query  188  VGPDSDAARRVRVLEQMWLNALWGG  212
            VG  +D AR V V+E++WL ALWGG
Sbjct  181  VGRGADPARAVEVVERLWLYALWGG  205


>gi|111026296|ref|YP_708579.1| TetR family transcriptional regulator [Rhodococcus jostii RHA1]
 gi|110825139|gb|ABH00421.1| transcriptional regulator, TetR family [Rhodococcus jostii RHA1]
Length=247

 Score = 84.7 bits (208),  Expect = 8e-15, Method: Compositional matrix adjust.
 Identities = 62/198 (32%), Positives = 98/198 (50%), Gaps = 9/198 (4%)

Query  18   RGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYFYFDSKYSVLAQILAEAT  77
            +GDR  QAIL  A E+L   P   +S+  ++ RAG++RS FYFYF+SK+ VL+ +L+  T
Sbjct  45   KGDRREQAILEGAYEILRTEPLRNVSIDDLAKRAGLSRSSFYFYFESKWQVLSALLSSVT  104

Query  78   EELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRACNAARQSDMEIRDILER  137
             ++  AS     R PG SPE  +   +  V  V+  +  VLR    A  ++      L  
Sbjct  105  ADVFTASAMIFERPPGISPEAAIEHAVSEVMVVWERHGHVLREVGDAAAAE----PTLGA  160

Query  138  QFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALMLTGDALLVGPDSDAARR  197
            Q+  +L   +    A ++   A  ++ D P   R+LAA    M   +  L+   S+ A R
Sbjct  161  QWDKILGRFVDAAAAAIERDRAAGVALDGPP-ARSLAAALIWMGERNLGLMSMRSENAIR  219

Query  198  ----VRVLEQMWLNALWG  211
                V  +  +WL  ++G
Sbjct  220  TEDMVETVTTVWLRTVFG  237


>gi|312141723|ref|YP_004009059.1| tetr family transcriptional regulator [Rhodococcus equi 103S]
 gi|311891062|emb|CBH50381.1| putative TetR family transcriptional regulator [Rhodococcus equi 
103S]
Length=211

 Score = 82.0 bits (201),  Expect = 6e-14, Method: Compositional matrix adjust.
 Identities = 61/214 (29%), Positives = 103/214 (49%), Gaps = 9/214 (4%)

Query  1    VTSHAADEKQAAPPMRRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYF  60
            ++SH A   +       +G+  R AIL A   LLE+    E+++  IS  AGV RSGFYF
Sbjct  1    MSSHPASSDETRTRRANKGEERRAAILDAVERLLEDRTLDEINISDISRAAGVTRSGFYF  60

Query  61   YFDSKYSVLAQILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRA  120
            YFD+K   +A +      E++E ++ + AR+   SP + ++ +I  V   +  +  + RA
Sbjct  61   YFDNKAKAVAALSRTVYGEMQEGARGYLAREG--SPREMIDGLITEVIGTWERHPNLYRA  118

Query  121  CNAARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTA--HPISEDLPTLVRTLAATTA  178
               AR SD  +R++ +      +     V +AE  +G A   P S  L  ++  +     
Sbjct  119  LRDARDSDPTVREMWDHDRFSFVDPVASVIDAERTSGRAADGPDSRALAVVLLDMNDRAV  178

Query  179  LMLTGDALLVGPDSDAARRVR-VLEQMWLNALWG  211
              L+      GP++      R  L  +WLN+++G
Sbjct  179  ESLSRG----GPEALTPETAREALVAVWLNSIYG  208


>gi|325673017|ref|ZP_08152711.1| transcriptional regulator [Rhodococcus equi ATCC 33707]
 gi|325556270|gb|EGD25938.1| transcriptional regulator [Rhodococcus equi ATCC 33707]
Length=229

 Score = 81.6 bits (200),  Expect = 6e-14, Method: Compositional matrix adjust.
 Identities = 61/214 (29%), Positives = 103/214 (49%), Gaps = 9/214 (4%)

Query  1    VTSHAADEKQAAPPMRRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYF  60
            ++SH A   +       +G+  R AIL A   LLE+    E+++  IS  AGV RSGFYF
Sbjct  19   MSSHPASSDETRTRRANKGEERRAAILDAVERLLEDRTLDEINISDISRAAGVTRSGFYF  78

Query  61   YFDSKYSVLAQILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRA  120
            YFD+K   +A +      E++E ++ + AR+   SP + ++ +I  V   +  +  + RA
Sbjct  79   YFDNKAKAVAALSRTVYGEMQEGARGYLAREG--SPREMIDGLITEVIGTWERHPNLYRA  136

Query  121  CNAARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTA--HPISEDLPTLVRTLAATTA  178
               AR SD  +R++ +      +     V +AE  +G A   P S  L  ++  +     
Sbjct  137  LRDARDSDPTVREMWDHDRFSFVDPVASVIDAERTSGRAADGPDSRALAVVLLDMNDRAV  196

Query  179  LMLTGDALLVGPDSDAARRVR-VLEQMWLNALWG  211
              L+      GP++      R  L  +WLN+++G
Sbjct  197  ESLS----RGGPEALTPETAREALVAVWLNSIYG  226


>gi|302867732|ref|YP_003836369.1| regulatory protein TetR [Micromonospora aurantiaca ATCC 27029]
 gi|315505866|ref|YP_004084753.1| regulatory protein TetR [Micromonospora sp. L5]
 gi|302570591|gb|ADL46793.1| regulatory protein TetR [Micromonospora aurantiaca ATCC 27029]
 gi|315412485|gb|ADU10602.1| regulatory protein TetR [Micromonospora sp. L5]
Length=226

 Score = 75.5 bits (184),  Expect = 5e-12, Method: Compositional matrix adjust.
 Identities = 65/213 (31%), Positives = 93/213 (44%), Gaps = 11/213 (5%)

Query  11   AAPPMRRR-----GDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYFYFDSK  65
            AAP   RR     GD    AIL  A  LL E PFA++S+  ++  AG++R  FYFYF SK
Sbjct  10   AAPTRGRRAGRSTGDDRETAILATAERLLAERPFADISIDDLARGAGISRPTFYFYFPSK  69

Query  66   YSVLAQILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRACNAAR  125
             +VL  +L   TEE + A+     R   E P      +I    A +  +  V+ AC   R
Sbjct  70   DAVLLTLLDRVTEEADAAAGGVFERL-AEDPRAHWRELIARFHATFGGHRDVVLACAQVR  128

Query  126  QSDMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALMLTGDA  185
             ++ E+R +     +  +R      E+E   G A    + LP     +A  +       A
Sbjct  129  GTNAEVRRLWAEVLERWVRAVQAAIESERARGAA---PDGLPARDLAIALNSMNERVWYA  185

Query  186  LLVGPDSDAARR--VRVLEQMWLNALWGGGKAP  216
               G     A R  V VL  +WL A++     P
Sbjct  186  TFAGDGPAVAERDVVDVLLDVWLTAIYRTATPP  218


>gi|56966246|pdb|1U9O|A Chain A, Crystal Structure Of The Transcriptional Regulator Ethr 
In A Ligand Bound Conformation
 gi|56966247|pdb|1U9O|B Chain B, Crystal Structure Of The Transcriptional Regulator Ethr 
In A Ligand Bound Conformation
Length=236

 Score = 75.1 bits (183),  Expect = 7e-12, Method: Compositional matrix adjust.
 Identities = 70/226 (31%), Positives = 104/226 (47%), Gaps = 28/226 (12%)

Query  1    VTSHAADEKQAAPPMRRR-----GDRHRQAILRAARELLEETPFAELSVRAISLRAGVAR  55
            VT+ AA   QA+ P  RR     GD    AIL  A  LLE+ P A++SV  ++  AG++R
Sbjct  21   VTTSAA--SQASLPRGRRTARPSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISR  78

Query  56   SGFYFYFDSKYSVLAQILAEATEELEEASQHFSARQPGESPEQFVNRM-IGSVAAVYANN  114
              FYFYF SK +VL  +L     + + A Q   A  P ++  + + R  I      + ++
Sbjct  79   PTFYFYFPSKEAVLLTLLDRVVNQADMALQTL-AENPADTDRENMWRTGINVFFETFGSH  137

Query  115  DPVLRACNAARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLA  174
              V RA  AAR + +E+ ++     Q  +  T  V +AE   G A           RTL 
Sbjct  138  KAVTRAGQAARATSVEVAELWSTFMQKWIAYTAAVIDAERDRGAAP----------RTLP  187

Query  175  A---TTALMLTGDALLVG------PDSDAARRVRVLEQMWLNALWG  211
            A    TAL L  +  L        P    AR +  L  +W+ +++G
Sbjct  188  AHELATALNLMNERTLFASFAGEQPSVPEARVLDTLVHIWVTSIYG  233


>gi|56966245|pdb|1U9N|A Chain A, Crystal Structure Of The Transcriptional Regulator Ethr 
In A Ligand Bound Conformation Opens Therapeutic Perspectives 
Against Tuberculosis And Leprosy
Length=236

 Score = 73.9 bits (180),  Expect = 1e-11, Method: Compositional matrix adjust.
 Identities = 70/226 (31%), Positives = 103/226 (46%), Gaps = 28/226 (12%)

Query  1    VTSHAADEKQAAPPMRRR-----GDRHRQAILRAARELLEETPFAELSVRAISLRAGVAR  55
            VT+ AA   QA+ P  RR     GD    AIL  A  LLE+ P A++SV  ++  AG++R
Sbjct  21   VTTSAA--SQASLPRGRRTARPSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISR  78

Query  56   SGFYFYFDSKYSVLAQILAEATEELEEASQHFSARQPGESPEQFVNRM-IGSVAAVYANN  114
              FYFYF SK +VL  +L     + + A Q   A  P ++  +   R  I      + ++
Sbjct  79   PTFYFYFPSKEAVLLTLLDRVVNQADXALQTL-AENPADTDRENXWRTGINVFFETFGSH  137

Query  115  DPVLRACNAARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLA  174
              V RA  AAR + +E+ ++     Q  +  T  V +AE   G A           RTL 
Sbjct  138  KAVTRAGQAARATSVEVAELWSTFXQKWIAYTAAVIDAERDRGAAP----------RTLP  187

Query  175  A---TTALMLTGDALLVG------PDSDAARRVRVLEQMWLNALWG  211
            A    TAL L  +  L        P    AR +  L  +W+ +++G
Sbjct  188  AHELATALNLXNERTLFASFAGEQPSVPEARVLDTLVHIWVTSIYG  233


>gi|317457508|gb|ADV29775.1| transcriptional regulatory repressor protein EthR [Mycobacterium 
tuberculosis]
Length=216

 Score = 73.9 bits (180),  Expect = 1e-11, Method: Compositional matrix adjust.
 Identities = 69/229 (31%), Positives = 106/229 (47%), Gaps = 28/229 (12%)

Query  1    VTSHAADEKQAAPPMRRR-----GDRHRQAILRAARELLEETPFAELSVRAISLRAGVAR  55
            +T+ AA   QA+ P  RR     GD    AIL  A  LLE+ P A++SV  ++  AG++R
Sbjct  1    MTTSAA--SQASLPRGRRTARPSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISR  58

Query  56   SGFYFYFDSKYSVLAQILAEATEELEEASQHFSARQPGESPEQFVNRM-IGSVAAVYANN  114
              FYFYF SK +VL  +L     + + A Q   A  P ++  + + R  I  +   + ++
Sbjct  59   PTFYFYFPSKEAVLLTLLDRVVNQADMALQTL-AENPADTDRENMWRTGINVLFETFGSH  117

Query  115  DPVLRACNAARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLA  174
              V RA  AAR + +E+ ++     Q  +  T  V +AE   G A           RTL 
Sbjct  118  KAVTRAGQAARATSVEVAELWSTFMQKWIAYTAAVIDAERDRGAAP----------RTLP  167

Query  175  A---TTALMLTGDALLVG------PDSDAARRVRVLEQMWLNALWGGGK  214
            A    TAL L  +  L        P    AR +  L  +W+ +++G  +
Sbjct  168  AHELATALNLMNERTLFASFAGEQPSVPEARVLDTLVHIWVTSIYGENR  216


>gi|254574835|pdb|3G1M|A Chain A, Ethr From Mycobacterium Tuberculosis In Complex With 
Compound Bdm31381
 gi|305677856|pdb|3O8G|A Chain A, Ethr From Mycobacterium Tuberculosis In Complex With 
Compound Bdm14801
 gi|305677857|pdb|3O8H|A Chain A, Ethr From Mycobacterium Tuberculosis In Complex With 
Compound Bdm14950
Length=236

 Score = 73.6 bits (179),  Expect = 2e-11, Method: Compositional matrix adjust.
 Identities = 69/226 (31%), Positives = 104/226 (47%), Gaps = 28/226 (12%)

Query  1    VTSHAADEKQAAPPMRRR-----GDRHRQAILRAARELLEETPFAELSVRAISLRAGVAR  55
            +T+ AA   QA+ P  RR     GD    AIL  A  LLE+ P A++SV  ++  AG++R
Sbjct  21   MTTSAA--SQASLPRGRRTARPSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISR  78

Query  56   SGFYFYFDSKYSVLAQILAEATEELEEASQHFSARQPGESPEQFVNRM-IGSVAAVYANN  114
              FYFYF SK +VL  +L     + + A Q   A  P ++  + + R  I      + ++
Sbjct  79   PTFYFYFPSKEAVLLTLLDRVVNQADMALQTL-AENPADTDRENMWRTGINVFFETFGSH  137

Query  115  DPVLRACNAARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLA  174
              V RA  AAR + +E+ ++     Q  +  T  V +AE   G A           RTL 
Sbjct  138  KAVTRAGQAARATSVEVAELWSTFMQKWIAYTAAVIDAERDRGAAP----------RTLP  187

Query  175  A---TTALMLTGDALLVG------PDSDAARRVRVLEQMWLNALWG  211
            A    TAL L  +  L        P    AR +  L  +W+ +++G
Sbjct  188  AHELATALNLMNERTLFASFAGEQPSVPEARVLDTLVHIWVTSIYG  233


>gi|254574836|pdb|3G1O|A Chain A, Ethr From Mycobacterium Tuberculosis In Complex With 
Compound Bdm14500
Length=255

 Score = 73.6 bits (179),  Expect = 2e-11, Method: Compositional matrix adjust.
 Identities = 67/225 (30%), Positives = 99/225 (44%), Gaps = 26/225 (11%)

Query  1    VTSHAADEKQAAPPMRRR-----GDRHRQAILRAARELLEETPFAELSVRAISLRAGVAR  55
            +T+ AA   QA+ P  RR     GD    AIL  A  LLE+ P A++SV  ++  AG++R
Sbjct  20   MTTSAA--SQASLPRGRRTARPSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISR  77

Query  56   SGFYFYFDSKYSVLAQILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANND  115
              FYFYF SK +VL  +L     + + A Q  +        E      I      + ++ 
Sbjct  78   PTFYFYFPSKEAVLLTLLDRVVNQADMALQTLAENPADTDRENMWRTGINVFFETFGSHK  137

Query  116  PVLRACNAARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAA  175
             V RA  AAR + +E+ ++     Q  +  T  V +AE   G A           RTL A
Sbjct  138  AVTRAGQAARATSVEVAELWSTFMQKWIAYTAAVIDAERDRGAAP----------RTLPA  187

Query  176  ---TTALMLTGDALLVG------PDSDAARRVRVLEQMWLNALWG  211
                TAL L  +  L        P    AR +  L  +W+ +++G
Sbjct  188  HELATALNLMNERTLFASFAGEQPSVPEARVLDTLVHIWVTSIYG  232


>gi|317457510|gb|ADV29776.1| transcriptional regulatory repressor protein EthR [Mycobacterium 
tuberculosis]
Length=216

 Score = 73.6 bits (179),  Expect = 2e-11, Method: Compositional matrix adjust.
 Identities = 67/228 (30%), Positives = 100/228 (44%), Gaps = 26/228 (11%)

Query  1    VTSHAADEKQAAPPMRRR-----GDRHRQAILRAARELLEETPFAELSVRAISLRAGVAR  55
            +T+ AA   QA+ P  RR     GD    AIL  A  LLE+ P A++SV  ++  AG++R
Sbjct  1    MTTSAA--SQASLPRGRRTARPSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISR  58

Query  56   SGFYFYFDSKYSVLAQILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANND  115
              FYFYF SK +VL  +L     + + A Q  +        E      I      + ++ 
Sbjct  59   PTFYFYFPSKEAVLLTLLDRVVNQADMALQTLAENPTDTDRENMWRTGINVFFETFGSHK  118

Query  116  PVLRACNAARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAA  175
             V RA  AAR + +E+ ++     Q  +  T  V +AE   G A           RTL A
Sbjct  119  AVTRAGQAARATSVEVAELWSTFMQKWIAYTAAVIDAERDRGAAP----------RTLPA  168

Query  176  ---TTALMLTGDALLVG------PDSDAARRVRVLEQMWLNALWGGGK  214
                TAL L  +  L        P    AR +  L  +W+ +++G  +
Sbjct  169  HELATALNLMNERTLFASFAGEQPSVPEARVLDTLVHIWVTSIYGENR  216


>gi|254574834|pdb|3G1L|A Chain A, Ethr From Mycobacterium Tuberculosis In Complex With 
Compound Bdm14744
Length=256

 Score = 73.6 bits (179),  Expect = 2e-11, Method: Compositional matrix adjust.
 Identities = 69/226 (31%), Positives = 104/226 (47%), Gaps = 28/226 (12%)

Query  1    VTSHAADEKQAAPPMRRR-----GDRHRQAILRAARELLEETPFAELSVRAISLRAGVAR  55
            +T+ AA   QA+ P  RR     GD    AIL  A  LLE+ P A++SV  ++  AG++R
Sbjct  21   MTTSAA--SQASLPRGRRTARPSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISR  78

Query  56   SGFYFYFDSKYSVLAQILAEATEELEEASQHFSARQPGESPEQFVNRM-IGSVAAVYANN  114
              FYFYF SK +VL  +L     + + A Q   A  P ++  + + R  I      + ++
Sbjct  79   PTFYFYFPSKEAVLLTLLDRVVNQADMALQTL-AENPADTDRENMWRTGINVFFETFGSH  137

Query  115  DPVLRACNAARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLA  174
              V RA  AAR + +E+ ++     Q  +  T  V +AE   G A           RTL 
Sbjct  138  KAVTRAGQAARATSVEVAELWSTFMQKWIAYTAAVIDAERDRGAAP----------RTLP  187

Query  175  A---TTALMLTGDALLVG------PDSDAARRVRVLEQMWLNALWG  211
            A    TAL L  +  L        P    AR +  L  +W+ +++G
Sbjct  188  AHELATALNLMNERTLFASFAGEQPSVPEARVLDTLVHIWVTSIYG  233


>gi|15610991|ref|NP_218372.1| transcriptional regulatory repressor protein (TETR-family) ETHR 
[Mycobacterium tuberculosis H37Rv]
 gi|15843486|ref|NP_338523.1| TetR family transcriptional regulator [Mycobacterium tuberculosis 
CDC1551]
 gi|31795029|ref|NP_857522.1| transcriptional regulatory repressor protein (TETR-family) ETHR 
[Mycobacterium bovis AF2122/97]
 83 more sequence titles
 Length=216

 Score = 73.6 bits (179),  Expect = 2e-11, Method: Compositional matrix adjust.
 Identities = 69/229 (31%), Positives = 105/229 (46%), Gaps = 28/229 (12%)

Query  1    VTSHAADEKQAAPPMRRR-----GDRHRQAILRAARELLEETPFAELSVRAISLRAGVAR  55
            +T+ AA   QA+ P  RR     GD    AIL  A  LLE+ P A++SV  ++  AG++R
Sbjct  1    MTTSAA--SQASLPRGRRTARPSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISR  58

Query  56   SGFYFYFDSKYSVLAQILAEATEELEEASQHFSARQPGESPEQFVNRM-IGSVAAVYANN  114
              FYFYF SK +VL  +L     + + A Q   A  P ++  + + R  I      + ++
Sbjct  59   PTFYFYFPSKEAVLLTLLDRVVNQADMALQTL-AENPADTDRENMWRTGINVFFETFGSH  117

Query  115  DPVLRACNAARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLA  174
              V RA  AAR + +E+ ++     Q  +  T  V +AE   G A           RTL 
Sbjct  118  KAVTRAGQAARATSVEVAELWSTFMQKWIAYTAAVIDAERDRGAAP----------RTLP  167

Query  175  A---TTALMLTGDALLVG------PDSDAARRVRVLEQMWLNALWGGGK  214
            A    TAL L  +  L        P    AR +  L  +W+ +++G  +
Sbjct  168  AHELATALNLMNERTLFASFAGEQPSVPEARVLDTLVHIWVTSIYGENR  216


>gi|240168331|ref|ZP_04746990.1| transcriptional regulatory repressor protein [Mycobacterium kansasii 
ATCC 12478]
Length=215

 Score = 73.2 bits (178),  Expect = 3e-11, Method: Compositional matrix adjust.
 Identities = 59/204 (29%), Positives = 90/204 (45%), Gaps = 14/204 (6%)

Query  16   RRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYFYFDSKYSVLAQILAE  75
            R  GD    AIL  A +LL++ P A++SV  ++  AG++R  FYFYF SK +VL  +L  
Sbjct  19   RPSGDDRELAILVTAEKLLKDRPLADISVDDLAKGAGISRPTFYFYFPSKEAVLLTLLDR  78

Query  76   ATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRACNAARQSDMEIRDIL  135
               E + A ++   + P    +      I      + ++  V RA  AAR +  E+R + 
Sbjct  79   VVTEADTALENL-IQAPDADRDTMWRTGINVFFETFGSHKAVTRAGQAARATSAEVRHLW  137

Query  136  ERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALMLTGDALLVG------  189
                Q  +  T  V E E   G A       P  V  L   TAL L  +  L        
Sbjct  138  STFMQKWISYTAEVIETERDRGAA-------PVTVPALELATALNLMNERTLFASFAAEQ  190

Query  190  PDSDAARRVRVLEQMWLNALWGGG  213
            P    A  +  L  +W+++++G G
Sbjct  191  PCVPEAHVLDTLVHIWVSSIYGEG  214


>gi|296165492|ref|ZP_06848024.1| TetR family transcriptional regulator [Mycobacterium parascrofulaceum 
ATCC BAA-614]
 gi|295899160|gb|EFG78634.1| TetR family transcriptional regulator [Mycobacterium parascrofulaceum 
ATCC BAA-614]
Length=212

 Score = 72.0 bits (175),  Expect = 6e-11, Method: Compositional matrix adjust.
 Identities = 51/151 (34%), Positives = 77/151 (51%), Gaps = 5/151 (3%)

Query  26   ILRAARELLEETPFAELSVRAISLRAGVARSGFYFYFDSKYSVLAQILAEATEELEEASQ  85
            IL A   LL      ++SV  I   A V+R+ FYFYF SK+SV++ +L  A E++ +  Q
Sbjct  26   ILAATTRLLARQSLTDISVAQILTEAKVSRATFYFYFASKFSVVSGLLERAMEDIFQTVQ  85

Query  86   HFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRACNAARQSDMEIRDILERQFQVLLRE  145
             F AR P +SP   + R I +V   +  + PV +A N    ++ E+RD+     +  +  
Sbjct  86   PFLARSPEDSPTVALERSIRAVTRAWHRHRPVFQATNHHWHAEPELRDLWLAIAERFISA  145

Query  146  TIGVFEAEVKAGTAHPISEDLPTLVRTLAAT  176
                 E E  AG    I+  +P+  R LAAT
Sbjct  146  GAAEIERERAAGM---ITSPIPS--RMLAAT  171


>gi|169628081|ref|YP_001701730.1| TetR family transcriptional regulator [Mycobacterium abscessus 
ATCC 19977]
 gi|169240048|emb|CAM61076.1| Putative transcriptional regulator, TetR family [Mycobacterium 
abscessus]
Length=212

 Score = 71.6 bits (174),  Expect = 6e-11, Method: Compositional matrix adjust.
 Identities = 62/205 (31%), Positives = 95/205 (47%), Gaps = 18/205 (8%)

Query  16   RRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYFYFDSKYSVLAQILAE  75
            R  GD   QAIL  A ELL + P A++SV  ++  AG++R  FYFYF SK SVL   L  
Sbjct  13   RPSGDERIQAILATAEELLGKRPLADVSVDDLARGAGISRPTFYFYFSSKESVL---LTL  69

Query  76   ATEELEEASQHFSARQPG--ESPEQFVNRMIGSVAAVYANNDPVLRACNAARQSDMEIRD  133
            A   +EEA  + ++  P    SP Q+   +I +    + ++  +  A ++ + +  E+  
Sbjct  70   AERIIEEADANVASIDPAAMTSPAQYWRAVIKAYFDAFGSHRALTVALSSMQGTSPELDQ  129

Query  134  ILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALMLTGDALLVG----  189
                  +  +  T    EAE   G A       P++V       AL L   A++      
Sbjct  130  RWSEVTENWVANTTVGIEAERARGAA-------PSVVPARDIAIALNLINQAMMRATFTG  182

Query  190  --PDSDAARRVRVLEQMWLNALWGG  212
              P  D  + V  L  +WLNA++GG
Sbjct  183  QQPAVDDGKVVDTLLHVWLNAIYGG  207


>gi|183985374|ref|YP_001853665.1| TetR family transcriptional regulator [Mycobacterium marinum 
M]
 gi|183178700|gb|ACC43810.1| transcriptional regulatory repressor protein (TetR-family) EthR 
[Mycobacterium marinum M]
Length=216

 Score = 70.1 bits (170),  Expect = 2e-10, Method: Compositional matrix adjust.
 Identities = 61/212 (29%), Positives = 95/212 (45%), Gaps = 15/212 (7%)

Query  9    KQAAPPMRRR-----GDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYFYFD  63
             QA+P   RR     GD    AIL  A +LLE+ P  ++SV  ++  AG++R  FYFYF 
Sbjct  8    SQASPSRGRRSARPSGDERELAILNTAEKLLEDRPMVDISVDDLAKGAGISRPTFYFYFP  67

Query  64   SKYSVLAQILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRACNA  123
            SK +VL  +L     E + A  +  A+ P           I      + ++  V++    
Sbjct  68   SKEAVLLTLLDRVVNEADAALDNL-AQAPDVDHVTMWRNGINVFFETFGSHRAVVQGGQG  126

Query  124  ARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALM---  180
             R    E+R++     Q  +  T  + EAE + G A P++  LP L   LA    LM   
Sbjct  127  VRSISAEVRELWSTFMQKWIAYTAKIIEAERERGAA-PVT--LPAL--ELATALNLMNER  181

Query  181  -LTGDALLVGPDSDAARRVRVLEQMWLNALWG  211
             L+   L   P       V  L  +W+++++G
Sbjct  182  TLSASFLAEEPSVPETHVVDTLVHIWVSSIYG  213


>gi|342860108|ref|ZP_08716760.1| TetR family transcriptional regulator [Mycobacterium colombiense 
CECT 3035]
 gi|342132486|gb|EGT85715.1| TetR family transcriptional regulator [Mycobacterium colombiense 
CECT 3035]
Length=213

 Score = 69.7 bits (169),  Expect = 3e-10, Method: Compositional matrix adjust.
 Identities = 59/204 (29%), Positives = 94/204 (47%), Gaps = 16/204 (7%)

Query  15   MRRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYFYFDSKYSVLAQIL-  73
            +R  GD   QAIL  A  LLEE   A++SV  ++  AG++R  FYFYF SK +VL  +L 
Sbjct  16   IRPTGDEREQAILATAERLLEERSLADISVDDLAKGAGISRPTFYFYFKSKEAVLLSLLE  75

Query  74   ---AEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRACNAARQSDME  130
               A A  E + A     A      P +     I +    ++ +  V R    A  +  E
Sbjct  76   PVIARADSEFDGAVHRLPA-----DPRRVWRNGIKAFFTAFSTHRAVARTATEALATSTE  130

Query  131  IRDILERQFQVLLRETIGVFEAEVKAGTA--HPISEDLPTLVRTLAATTAL-MLTGDALL  187
            +R +     Q  + +T  +  AE   G A  +  + DL T +  +   T +  L+ +   
Sbjct  131  LRSLWSGYMQKWIDQTAAMITAERARGAAPDNIPAADLATSLNQMNERTMMAALSAET--  188

Query  188  VGPDSDAARRVRVLEQMWLNALWG  211
              P  +AAR V  L  +W+++++G
Sbjct  189  --PAVEAARVVDTLTHIWISSIYG  210


>gi|298246923|ref|ZP_06970728.1| transcriptional regulator, TetR family [Ktedonobacter racemifer 
DSM 44963]
 gi|297549582|gb|EFH83448.1| transcriptional regulator, TetR family [Ktedonobacter racemifer 
DSM 44963]
Length=220

 Score = 69.3 bits (168),  Expect = 4e-10, Method: Compositional matrix adjust.
 Identities = 55/190 (29%), Positives = 89/190 (47%), Gaps = 1/190 (0%)

Query  23   RQAILRAARELLEETPFAELSVRAISLRAGVARSGFYFYFDSKYSVLAQILAEATEELEE  82
            R+AIL A  +LL    F ELSV  I   A V+R+ FYFYF+SKY VL +++     + + 
Sbjct  24   RKAILDATEQLLAHQRFDELSVADILSSAQVSRASFYFYFESKYVVLGELVRRVVNQAQV  83

Query  83   ASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRACNAARQSDMEIRDILERQFQVL  142
            A+  +   +  ESPEQ + +       ++  + PVLRA     +SD  +  +     +  
Sbjct  84   AAGPW-VEEDIESPEQTLRQGTSQGLQLWIQHAPVLRAIVENWRSDERLAALWMEMMEGF  142

Query  143  LRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALMLTGDALLVGPDSDAARRVRVLE  202
             +      E +   G A   S D  TL  TL   +  +    A+      D  + + VL 
Sbjct  143  TQAATHRIERDRATGRAPRTSVDASTLASTLTWMSERIYYLAAIGHPAFHDEQQVIDVLT  202

Query  203  QMWLNALWGG  212
            ++WL+ ++ G
Sbjct  203  EVWLSVIYNG  212


>gi|254773230|ref|ZP_05214746.1| hypothetical protein MaviaA2_00911 [Mycobacterium avium subsp. 
avium ATCC 25291]
Length=213

 Score = 68.6 bits (166),  Expect = 6e-10, Method: Compositional matrix adjust.
 Identities = 60/204 (30%), Positives = 97/204 (48%), Gaps = 16/204 (7%)

Query  15   MRRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYFYFDSK----YSVLA  70
            +R  GD   QAIL  A  LLE  PFA +SV  ++  AG++R  FYFYF SK     S+L 
Sbjct  16   IRPTGDEREQAILATAERLLETRPFAGISVDDLAKGAGLSRPTFYFYFKSKEAVVLSLLE  75

Query  71   QILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRACNAARQSDME  130
             ++A A  E + A Q    R P + P +     I +    ++++  + RA   A  +  E
Sbjct  76   PVIARADAEFDGAVQ----RLPTD-PRRVWRNGIKAFFTAFSSHRALARAATEALATSSE  130

Query  131  IRDILERQFQVLLRETIGVFEAEVKAGTAHPI--SEDLPTLVRTLAATTAL-MLTGDALL  187
            +R +     Q  + +T  +  AE + G A     + DL T +  +   T +  L+ +   
Sbjct  131  LRSVWSGFMQKWIDQTAAMITAERERGAAPDTIPAADLATSLNQMNERTMMAALSAETPA  190

Query  188  VGPDSDAARRVRVLEQMWLNALWG  211
            V  D    R V  L  +W+++++G
Sbjct  191  VAED----RVVDTLTHIWVSSIYG  210


>gi|118620041|ref|YP_908373.1| TetR family transcriptional regulator [Mycobacterium ulcerans 
Agy99]
 gi|118572151|gb|ABL06902.1| transcriptional regulatory repressor protein (TetR-family) EthR 
[Mycobacterium ulcerans Agy99]
Length=215

 Score = 68.6 bits (166),  Expect = 6e-10, Method: Compositional matrix adjust.
 Identities = 57/203 (29%), Positives = 91/203 (45%), Gaps = 10/203 (4%)

Query  16   RRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYFYFDSKYSVLAQILAE  75
            R  GD    AIL  A +LLE+ P  ++SV  ++  AG++R  FYFYF SK +VL  +L  
Sbjct  19   RPSGDERELAILNTAEKLLEDRPMVDISVDDLAKGAGISRPTFYFYFPSKEAVLLTLLDR  78

Query  76   ATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRACNAARQSDMEIRDIL  135
               E + A  +  A+ P           I      + ++  V++     R    E+R++ 
Sbjct  79   VVNEADAALDNL-AQAPDVDHVTMWRNGINVFFETFGSHRAVVQGGQGVRSISTEVRELW  137

Query  136  ERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALM----LTGDALLVGPD  191
                Q  +  T  + EAE + G A P++  LP L   LA    LM    L+   L   P 
Sbjct  138  STFMQKWIAYTAKIIEAERERGAA-PVT--LPAL--ELATALNLMNERTLSASFLAEEPS  192

Query  192  SDAARRVRVLEQMWLNALWGGGK  214
                  V  L  +W+++++G  +
Sbjct  193  VPETHVVDTLVHVWVSSIYGAAR  215


>gi|256393334|ref|YP_003114898.1| TetR family transcriptional regulator [Catenulispora acidiphila 
DSM 44928]
 gi|256359560|gb|ACU73057.1| transcriptional regulator, TetR family [Catenulispora acidiphila 
DSM 44928]
Length=302

 Score = 68.6 bits (166),  Expect = 7e-10, Method: Compositional matrix adjust.
 Identities = 51/131 (39%), Positives = 68/131 (52%), Gaps = 8/131 (6%)

Query  10   QAAPPMRRRG-----DRH-RQAILRAARELLEETPFAELSVRAISLRAGVARSGFYFYFD  63
            +A PP R  G     DR  R+AIL A R LL+E  F ELSV  I   AGVAR  FYFYF 
Sbjct  12   EATPPRRTAGRAGRDDREVREAILVATRRLLDERRFDELSVADILTAAGVARGSFYFYFA  71

Query  64   SKYSVLAQILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRACNA  123
             K  VLA++   A     EA++ + A    + P + +   I   A ++    PVLRA   
Sbjct  72   GKNQVLAELTRRAVALGHEAAEPWLAST--DDPRETIRHGISEGAKLWRAEAPVLRAMVE  129

Query  124  ARQSDMEIRDI  134
              +SD E+ ++
Sbjct  130  NWRSDEELGEL  140


>gi|118462741|ref|YP_879467.1| TetR family transcriptional regulator [Mycobacterium avium 104]
 gi|118164028|gb|ABK64925.1| transcriptional regulator, TetR family protein [Mycobacterium 
avium 104]
Length=213

 Score = 67.8 bits (164),  Expect = 9e-10, Method: Compositional matrix adjust.
 Identities = 60/204 (30%), Positives = 97/204 (48%), Gaps = 16/204 (7%)

Query  15   MRRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYFYFDSK----YSVLA  70
            +R  GD   QAIL  A  LLE  PFA +SV  ++  AG++R  FYFYF SK     S+L 
Sbjct  16   IRPTGDEREQAILATALRLLETRPFAGISVDDLAKGAGLSRPTFYFYFKSKEAVVLSLLE  75

Query  71   QILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRACNAARQSDME  130
             ++A A  E + A Q    R P + P +     I +    ++++  + RA   A  +  E
Sbjct  76   PVIARADAEFDGAVQ----RLPTD-PRRVWRNGIKAFFTAFSSHRALARAATEALATSSE  130

Query  131  IRDILERQFQVLLRETIGVFEAEVKAGTAHPI--SEDLPTLVRTLAATTAL-MLTGDALL  187
            +R +     Q  + +T  +  AE + G A     + DL T +  +   T +  L+ +   
Sbjct  131  LRSVWSGFMQKWIDQTAAMITAERERGAAPDTIPAADLATSLNQMNERTMMAALSAETPA  190

Query  188  VGPDSDAARRVRVLEQMWLNALWG  211
            V  D    R V  L  +W+++++G
Sbjct  191  VAED----RVVDTLTHIWVSSIYG  210


>gi|288918443|ref|ZP_06412795.1| transcriptional regulator, TetR family [Frankia sp. EUN1f]
 gi|288350206|gb|EFC84431.1| transcriptional regulator, TetR family [Frankia sp. EUN1f]
Length=212

 Score = 67.8 bits (164),  Expect = 9e-10, Method: Compositional matrix adjust.
 Identities = 57/189 (31%), Positives = 94/189 (50%), Gaps = 11/189 (5%)

Query  26   ILRAARELLEETPFAELSVRAISLRAGVARSGFYFYFDSKYSVLAQILAEATEELEEASQ  85
            ++RA  ELL+E    E++V AI+  AGV+RS FYFYF+ K +  A + ++  +E+  A+ 
Sbjct  1    MMRALDELLKERDLDEINVAAITAEAGVSRSAFYFYFEDKAACAAALGSDVYQEVLTATH  60

Query  86   HFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRACNAARQSDMEIRDILERQFQVLLRE  145
                   G  P + ++R I +V   + N+  + +    ARQ    +R + +   +  +  
Sbjct  61   ALIT--SGGPPRERISRTIQAVLTSWENHRHLFQGMLVARQRSETVRRLWDEYRESFIGP  118

Query  146  TIGVFEAEVKAGTAH--PISEDLPTLVRTLAATTALML-TGDALLVGPDSDAARRVRVLE  202
               + +AE  AGTA   P S  L T++  L   +   L TG     GP S A +R   L 
Sbjct  119  LAEMIDAERAAGTASAGPDSRALVTVLLELNDRSLEQLSTG-----GPLS-ADQRAEALT  172

Query  203  QMWLNALWG  211
             +WL  ++G
Sbjct  173  TIWLRTIYG  181


>gi|41406277|ref|NP_959113.1| hypothetical protein MAP0179c [Mycobacterium avium subsp. paratuberculosis 
K-10]
 gi|41394625|gb|AAS02496.1| hypothetical protein MAP_0179c [Mycobacterium avium subsp. paratuberculosis 
K-10]
Length=213

 Score = 67.8 bits (164),  Expect = 9e-10, Method: Compositional matrix adjust.
 Identities = 60/204 (30%), Positives = 97/204 (48%), Gaps = 16/204 (7%)

Query  15   MRRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYFYFDSK----YSVLA  70
            +R  GD   QAIL  A  LLE  PFA +SV  ++  AG++R  FYFYF SK     S+L 
Sbjct  16   IRPTGDEREQAILATAERLLETRPFAGISVDDLAKGAGLSRPTFYFYFKSKEAVVLSLLE  75

Query  71   QILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRACNAARQSDME  130
             ++A A  E + A Q    R P + P +     I +    ++++  + RA   A  +  E
Sbjct  76   PVIARADAEFDGAVQ----RLPTD-PRRVWRNGIKAFFTAFSSHRALARAATEALATSSE  130

Query  131  IRDILERQFQVLLRETIGVFEAEVKAGTAHPI--SEDLPTLVRTLAATTAL-MLTGDALL  187
            +R +     Q  + +T  +  AE + G A     + DL T +  +   T +  L+ +   
Sbjct  131  LRAVWSGFMQKWIDQTAAMITAERERGAAPDTIPAADLATSLNQMNERTMMAALSAETPA  190

Query  188  VGPDSDAARRVRVLEQMWLNALWG  211
            V  D    R V  L  +W+++++G
Sbjct  191  VAED----RVVDTLTHIWVSSIYG  210


>gi|336461862|gb|EGO40717.1| transcriptional regulator [Mycobacterium avium subsp. paratuberculosis 
S397]
Length=213

 Score = 67.4 bits (163),  Expect = 1e-09, Method: Compositional matrix adjust.
 Identities = 60/204 (30%), Positives = 97/204 (48%), Gaps = 16/204 (7%)

Query  15   MRRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYFYFDSK----YSVLA  70
            +R  GD   QAIL  A  LLE  PFA +SV  ++  AG++R  FYFYF SK     S+L 
Sbjct  16   IRPTGDEREQAILATAGRLLETRPFAGISVDDLAKGAGLSRPTFYFYFKSKEAVVLSLLE  75

Query  71   QILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRACNAARQSDME  130
             ++A A  E + A Q    R P + P +     I +    ++++  + RA   A  +  E
Sbjct  76   PVIARADAEFDGAVQ----RLPTD-PRRVWRNGIKAFFTAFSSHRALARAATEALATSSE  130

Query  131  IRDILERQFQVLLRETIGVFEAEVKAGTAHPI--SEDLPTLVRTLAATTAL-MLTGDALL  187
            +R +     Q  + +T  +  AE + G A     + DL T +  +   T +  L+ +   
Sbjct  131  LRAVWSGFMQKWIDQTAAMITAERERGAAPDTIPAADLATSLNQMNERTMMAALSAETPA  190

Query  188  VGPDSDAARRVRVLEQMWLNALWG  211
            V  D    R V  L  +W+++++G
Sbjct  191  VAED----RVVDTLTHIWVSSIYG  210


>gi|118462781|ref|YP_884182.1| TetR family transcriptional regulator [Mycobacterium avium 104]
 gi|118164068|gb|ABK64965.1| transcriptional regulator, TetR family protein, putative [Mycobacterium 
avium 104]
Length=192

 Score = 67.4 bits (163),  Expect = 2e-09, Method: Compositional matrix adjust.
 Identities = 38/101 (38%), Positives = 58/101 (58%), Gaps = 0/101 (0%)

Query  21   RHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYFYFDSKYSVLAQILAEATEEL  80
            R   ++  A   LLE  PF ++SV  I   AGV+R+ FYFYF SK+SVL+ +L +A  ++
Sbjct  2    RAVDSLFAATLTLLESRPFTDISVADILEVAGVSRATFYFYFSSKFSVLSGLLEQAMGDI  61

Query  81   EEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRAC  121
                Q F +R    SP++ + R + +V A +  +  VLRA 
Sbjct  62   FSTVQPFLSRSDDASPQEALERSLRAVTAAWHRHRAVLRAA  102


>gi|119871173|ref|YP_941125.1| TetR family transcriptional regulator [Mycobacterium sp. KMS]
 gi|119697262|gb|ABL94335.1| transcriptional regulator, TetR family [Mycobacterium sp. KMS]
Length=209

 Score = 66.2 bits (160),  Expect = 3e-09, Method: Compositional matrix adjust.
 Identities = 67/219 (31%), Positives = 97/219 (45%), Gaps = 33/219 (15%)

Query  9    KQAAPPMRRR-----GDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYFYFD  63
             QA  P  RR     GD   QAIL  A +LLE  PFAE+SV  ++  AG++R  FYFYF 
Sbjct  5    SQARAPRGRRSARPSGDDREQAILATAEQLLEARPFAEISVDDLAKGAGISRPTFYFYFG  64

Query  64   SKYSVL----AQILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLR  119
            SK +VL     +++ EA   LE A+ + ++        +      G+   V         
Sbjct  65   SKEAVLLTLWERVIREADAALENAASNATSEDVWRPGIKVFFDTFGAHRGV---------  115

Query  120  ACNAARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPI--SEDLPTLV-----RT  172
               A+   + E+RD+  R  Q  +  T    EAE + G A     + D+ T +     RT
Sbjct  116  TVAASGSDNAEVRDVFARFMQKWIDFTAATIEAERRRGAAPQTLPARDIATALNLMNERT  175

Query  173  LAATTALMLTGDALLVGPDSDAARRVRVLEQMWLNALWG  211
            L A  A    G    + PD    R +  L  +W  A++G
Sbjct  176  LLAAFAAETPG----IPPD----RVLDSLVHVWTCAVYG  206



Lambda     K      H
   0.319    0.131    0.370 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Effective search space used: 260686263632


  Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
    Posted date:  Sep 5, 2011  4:36 AM
  Number of letters in database: 5,219,829,388
  Number of sequences in database:  15,229,318



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40