BLASTP 2.2.25+
Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
15,229,318 sequences; 5,219,829,388 total letters
Query= Rv3058c
Length=216
Score E
Sequences producing significant alignments: (Bits) Value
gi|339299506|gb|AEJ51616.1| TetR family transcriptional regulato... 439 2e-121
gi|15842625|ref|NP_337662.1| TetR family transcriptional regulat... 439 2e-121
gi|148824250|ref|YP_001289004.1| TetR family transcriptional reg... 438 2e-121
gi|15610195|ref|NP_217574.1| TetR family transcriptional regulat... 437 6e-121
gi|340628050|ref|YP_004746502.1| putative transcriptional regula... 434 3e-120
gi|341602982|emb|CCC65660.1| possible transcriptional regulatory... 434 6e-120
gi|308406044|ref|ZP_07494903.2| transcriptional regulator, tetR-... 410 9e-113
gi|118618716|ref|YP_907048.1| TetR family transcriptional regula... 333 9e-90
gi|118465113|ref|YP_883088.1| TetR family transcriptional regula... 310 9e-83
gi|240171830|ref|ZP_04750489.1| TetR family transcriptional regu... 307 7e-82
gi|296171146|ref|ZP_06852594.1| TetR family transcriptional regu... 301 5e-80
gi|254776345|ref|ZP_05217861.1| transcriptional regulator, TetR ... 292 2e-77
gi|41409206|ref|NP_962042.1| hypothetical protein MAP3108c [Myco... 291 4e-77
gi|336459248|gb|EGO38193.1| transcriptional regulator [Mycobacte... 291 6e-77
gi|254820774|ref|ZP_05225775.1| transcriptional regulator, TetR ... 278 3e-73
gi|342858091|ref|ZP_08714746.1| TetR family transcriptional regu... 266 2e-69
gi|333991432|ref|YP_004524046.1| TetR family transcriptional reg... 264 7e-69
gi|118467960|ref|YP_886640.1| TetR family transcriptional regula... 213 1e-53
gi|120403026|ref|YP_952855.1| TetR family transcriptional regula... 211 7e-53
gi|315445222|ref|YP_004078101.1| TetR family transcriptional reg... 207 1e-51
gi|145224893|ref|YP_001135571.1| TetR family transcriptional reg... 206 2e-51
gi|169630503|ref|YP_001704152.1| TetR family transcriptional reg... 193 1e-47
gi|108798777|ref|YP_638974.1| TetR family transcriptional regula... 192 2e-47
gi|111026296|ref|YP_708579.1| TetR family transcriptional regula... 84.7 8e-15
gi|312141723|ref|YP_004009059.1| tetr family transcriptional reg... 82.0 6e-14
gi|325673017|ref|ZP_08152711.1| transcriptional regulator [Rhodo... 81.6 6e-14
gi|302867732|ref|YP_003836369.1| regulatory protein TetR [Microm... 75.5 5e-12
gi|56966246|pdb|1U9O|A Chain A, Crystal Structure Of The Transcr... 75.1 7e-12
gi|56966245|pdb|1U9N|A Chain A, Crystal Structure Of The Transcr... 73.9 1e-11
gi|317457508|gb|ADV29775.1| transcriptional regulatory repressor... 73.9 1e-11
gi|254574835|pdb|3G1M|A Chain A, Ethr From Mycobacterium Tubercu... 73.6 2e-11
gi|254574836|pdb|3G1O|A Chain A, Ethr From Mycobacterium Tubercu... 73.6 2e-11
gi|317457510|gb|ADV29776.1| transcriptional regulatory repressor... 73.6 2e-11
gi|254574834|pdb|3G1L|A Chain A, Ethr From Mycobacterium Tubercu... 73.6 2e-11
gi|15610991|ref|NP_218372.1| transcriptional regulatory represso... 73.6 2e-11
gi|240168331|ref|ZP_04746990.1| transcriptional regulatory repre... 73.2 3e-11
gi|296165492|ref|ZP_06848024.1| TetR family transcriptional regu... 72.0 6e-11
gi|169628081|ref|YP_001701730.1| TetR family transcriptional reg... 71.6 6e-11
gi|183985374|ref|YP_001853665.1| TetR family transcriptional reg... 70.1 2e-10
gi|342860108|ref|ZP_08716760.1| TetR family transcriptional regu... 69.7 3e-10
gi|298246923|ref|ZP_06970728.1| transcriptional regulator, TetR ... 69.3 4e-10
gi|254773230|ref|ZP_05214746.1| hypothetical protein MaviaA2_009... 68.6 6e-10
gi|118620041|ref|YP_908373.1| TetR family transcriptional regula... 68.6 6e-10
gi|256393334|ref|YP_003114898.1| TetR family transcriptional reg... 68.6 7e-10
gi|118462741|ref|YP_879467.1| TetR family transcriptional regula... 67.8 9e-10
gi|288918443|ref|ZP_06412795.1| transcriptional regulator, TetR ... 67.8 9e-10
gi|41406277|ref|NP_959113.1| hypothetical protein MAP0179c [Myco... 67.8 9e-10
gi|336461862|gb|EGO40717.1| transcriptional regulator [Mycobacte... 67.4 1e-09
gi|118462781|ref|YP_884182.1| TetR family transcriptional regula... 67.4 2e-09
gi|119871173|ref|YP_941125.1| TetR family transcriptional regula... 66.2 3e-09
>gi|339299506|gb|AEJ51616.1| TetR family transcriptional regulator [Mycobacterium tuberculosis
CCDC5180]
Length=225
Score = 439 bits (1128), Expect = 2e-121, Method: Compositional matrix adjust.
Identities = 216/216 (100%), Positives = 216/216 (100%), Gaps = 0/216 (0%)
Query 1 VTSHAADEKQAAPPMRRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYF 60
VTSHAADEKQAAPPMRRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYF
Sbjct 10 VTSHAADEKQAAPPMRRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYF 69
Query 61 YFDSKYSVLAQILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRA 120
YFDSKYSVLAQILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRA
Sbjct 70 YFDSKYSVLAQILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRA 129
Query 121 CNAARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALM 180
CNAARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALM
Sbjct 130 CNAARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALM 189
Query 181 LTGDALLVGPDSDAARRVRVLEQMWLNALWGGGKAP 216
LTGDALLVGPDSDAARRVRVLEQMWLNALWGGGKAP
Sbjct 190 LTGDALLVGPDSDAARRVRVLEQMWLNALWGGGKAP 225
>gi|15842625|ref|NP_337662.1| TetR family transcriptional regulator [Mycobacterium tuberculosis
CDC1551]
gi|254233688|ref|ZP_04927013.1| hypothetical protein TBCG_02994 [Mycobacterium tuberculosis C]
gi|13882940|gb|AAK47476.1| transcriptional regulator, TetR family [Mycobacterium tuberculosis
CDC1551]
gi|124599217|gb|EAY58321.1| hypothetical protein TBCG_02994 [Mycobacterium tuberculosis C]
gi|339295893|gb|AEJ48004.1| TetR family transcriptional regulator [Mycobacterium tuberculosis
CCDC5079]
Length=237
Score = 439 bits (1128), Expect = 2e-121, Method: Compositional matrix adjust.
Identities = 216/216 (100%), Positives = 216/216 (100%), Gaps = 0/216 (0%)
Query 1 VTSHAADEKQAAPPMRRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYF 60
VTSHAADEKQAAPPMRRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYF
Sbjct 22 VTSHAADEKQAAPPMRRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYF 81
Query 61 YFDSKYSVLAQILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRA 120
YFDSKYSVLAQILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRA
Sbjct 82 YFDSKYSVLAQILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRA 141
Query 121 CNAARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALM 180
CNAARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALM
Sbjct 142 CNAARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALM 201
Query 181 LTGDALLVGPDSDAARRVRVLEQMWLNALWGGGKAP 216
LTGDALLVGPDSDAARRVRVLEQMWLNALWGGGKAP
Sbjct 202 LTGDALLVGPDSDAARRVRVLEQMWLNALWGGGKAP 237
>gi|148824250|ref|YP_001289004.1| TetR family transcriptional regulator [Mycobacterium tuberculosis
F11]
gi|167969661|ref|ZP_02551938.1| transcriptional regulator, TetR family protein [Mycobacterium
tuberculosis H37Ra]
gi|253797843|ref|YP_003030844.1| transcriptional regulator, tetR-family [Mycobacterium tuberculosis
KZN 1435]
9 more sequence titles
Length=226
Score = 438 bits (1127), Expect = 2e-121, Method: Compositional matrix adjust.
Identities = 216/216 (100%), Positives = 216/216 (100%), Gaps = 0/216 (0%)
Query 1 VTSHAADEKQAAPPMRRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYF 60
VTSHAADEKQAAPPMRRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYF
Sbjct 11 VTSHAADEKQAAPPMRRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYF 70
Query 61 YFDSKYSVLAQILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRA 120
YFDSKYSVLAQILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRA
Sbjct 71 YFDSKYSVLAQILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRA 130
Query 121 CNAARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALM 180
CNAARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALM
Sbjct 131 CNAARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALM 190
Query 181 LTGDALLVGPDSDAARRVRVLEQMWLNALWGGGKAP 216
LTGDALLVGPDSDAARRVRVLEQMWLNALWGGGKAP
Sbjct 191 LTGDALLVGPDSDAARRVRVLEQMWLNALWGGGKAP 226
>gi|15610195|ref|NP_217574.1| TetR family transcriptional regulator [Mycobacterium tuberculosis
H37Rv]
gi|31794236|ref|NP_856729.1| TetR family transcriptional regulator [Mycobacterium bovis AF2122/97]
gi|121638943|ref|YP_979167.1| TetR family transcriptional regulator [Mycobacterium bovis BCG
str. Pasteur 1173P2]
54 more sequence titles
gi|148662911|ref|YP_001284434.1| TetR family transcriptional regulator [Mycobacterium tuberculosis
H37Ra]
gi|224991435|ref|YP_002646124.1| putative transcriptional regulatory protein [Mycobacterium bovis
BCG str. Tokyo 172]
gi|254552133|ref|ZP_05142580.1| TetR family transcriptional regulator [Mycobacterium tuberculosis
'98-R604 INH-RIF-EM']
gi|289448737|ref|ZP_06438481.1| transcriptional regulator, tetR-family [Mycobacterium tuberculosis
CPHL_A]
gi|289571262|ref|ZP_06451489.1| transcriptional regulator, tetR-family [Mycobacterium tuberculosis
T17]
gi|289575769|ref|ZP_06455996.1| transcriptional regulator, tetR-family [Mycobacterium tuberculosis
K85]
gi|289751731|ref|ZP_06511109.1| transcriptional regulator, tetR-family [Mycobacterium tuberculosis
T92]
gi|289755175|ref|ZP_06514553.1| transcriptional regulator [Mycobacterium tuberculosis EAS054]
gi|289759183|ref|ZP_06518561.1| transcriptional regulator [Mycobacterium tuberculosis T85]
gi|289763237|ref|ZP_06522615.1| transcriptional regulatory protein (probably tetR-family) [Mycobacterium
tuberculosis GM 1503]
gi|294993438|ref|ZP_06799129.1| TetR family transcriptional regulator [Mycobacterium tuberculosis
210]
gi|297635689|ref|ZP_06953469.1| TetR family transcriptional regulator [Mycobacterium tuberculosis
KZN 4207]
gi|297732687|ref|ZP_06961805.1| TetR family transcriptional regulator [Mycobacterium tuberculosis
KZN R506]
gi|298526529|ref|ZP_07013938.1| transcriptional regulatory protein (probably tetR-family) [Mycobacterium
tuberculosis 94_M4241A]
gi|306777364|ref|ZP_07415701.1| transcriptional regulator, tetR-family [Mycobacterium tuberculosis
SUMu001]
gi|306781268|ref|ZP_07419605.1| transcriptional regulator, tetR-family [Mycobacterium tuberculosis
SUMu002]
gi|306785909|ref|ZP_07424231.1| transcriptional regulator, tetR-family [Mycobacterium tuberculosis
SUMu003]
gi|306790263|ref|ZP_07428585.1| transcriptional regulator, tetR-family [Mycobacterium tuberculosis
SUMu004]
gi|306794758|ref|ZP_07433060.1| transcriptional regulator, tetR-family [Mycobacterium tuberculosis
SUMu005]
gi|306799000|ref|ZP_07437302.1| transcriptional regulator, tetR-family [Mycobacterium tuberculosis
SUMu006]
gi|306804843|ref|ZP_07441511.1| transcriptional regulator, tetR-family [Mycobacterium tuberculosis
SUMu008]
gi|306809036|ref|ZP_07445704.1| transcriptional regulator, tetR-family [Mycobacterium tuberculosis
SUMu007]
gi|306969136|ref|ZP_07481797.1| transcriptional regulator, tetR-family [Mycobacterium tuberculosis
SUMu009]
gi|306973480|ref|ZP_07486141.1| transcriptional regulator, tetR-family [Mycobacterium tuberculosis
SUMu010]
gi|307081191|ref|ZP_07490361.1| transcriptional regulator, tetR-family [Mycobacterium tuberculosis
SUMu011]
gi|313660019|ref|ZP_07816899.1| TetR family transcriptional regulator [Mycobacterium tuberculosis
KZN V2475]
gi|339633066|ref|YP_004724708.1| TetR family transcriptional regulator [Mycobacterium africanum
GM041182]
gi|1781155|emb|CAB06264.1| POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY TETR-FAMILY)
[Mycobacterium tuberculosis H37Rv]
gi|31619831|emb|CAD96771.1| POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY TETR-FAMILY)
[Mycobacterium bovis AF2122/97]
gi|121494591|emb|CAL73072.1| Possible transcriptional regulatory protein (probably tetR-family)
[Mycobacterium bovis BCG str. Pasteur 1173P2]
gi|148507063|gb|ABQ74872.1| TetR-family transcriptional regulator [Mycobacterium tuberculosis
H37Ra]
gi|224774550|dbj|BAH27356.1| putative transcriptional regulatory protein [Mycobacterium bovis
BCG str. Tokyo 172]
gi|289421695|gb|EFD18896.1| transcriptional regulator, tetR-family [Mycobacterium tuberculosis
CPHL_A]
gi|289540200|gb|EFD44778.1| transcriptional regulator, tetR-family [Mycobacterium tuberculosis
K85]
gi|289545016|gb|EFD48664.1| transcriptional regulator, tetR-family [Mycobacterium tuberculosis
T17]
gi|289692318|gb|EFD59747.1| transcriptional regulator, tetR-family [Mycobacterium tuberculosis
T92]
gi|289695762|gb|EFD63191.1| transcriptional regulator [Mycobacterium tuberculosis EAS054]
gi|289710743|gb|EFD74759.1| transcriptional regulatory protein (probably tetR-family) [Mycobacterium
tuberculosis GM 1503]
gi|289714747|gb|EFD78759.1| transcriptional regulator [Mycobacterium tuberculosis T85]
gi|298496323|gb|EFI31617.1| transcriptional regulatory protein (probably tetR-family) [Mycobacterium
tuberculosis 94_M4241A]
gi|308214256|gb|EFO73655.1| transcriptional regulator, tetR-family [Mycobacterium tuberculosis
SUMu001]
gi|308325911|gb|EFP14762.1| transcriptional regulator, tetR-family [Mycobacterium tuberculosis
SUMu002]
gi|308329433|gb|EFP18284.1| transcriptional regulator, tetR-family [Mycobacterium tuberculosis
SUMu003]
gi|308333278|gb|EFP22129.1| transcriptional regulator, tetR-family [Mycobacterium tuberculosis
SUMu004]
gi|308336933|gb|EFP25784.1| transcriptional regulator, tetR-family [Mycobacterium tuberculosis
SUMu005]
gi|308340749|gb|EFP29600.1| transcriptional regulator, tetR-family [Mycobacterium tuberculosis
SUMu006]
gi|308344616|gb|EFP33467.1| transcriptional regulator, tetR-family [Mycobacterium tuberculosis
SUMu007]
gi|308348564|gb|EFP37415.1| transcriptional regulator, tetR-family [Mycobacterium tuberculosis
SUMu008]
gi|308353290|gb|EFP42141.1| transcriptional regulator, tetR-family [Mycobacterium tuberculosis
SUMu009]
gi|308357123|gb|EFP45974.1| transcriptional regulator, tetR-family [Mycobacterium tuberculosis
SUMu010]
gi|308361075|gb|EFP49926.1| transcriptional regulator, tetR-family [Mycobacterium tuberculosis
SUMu011]
gi|326902720|gb|EGE49653.1| transcriptional regulator, tetR-family [Mycobacterium tuberculosis
W-148]
gi|339332422|emb|CCC28135.1| putative transcriptional regulatory protein (probably TETR-family)
[Mycobacterium africanum GM041182]
gi|344220894|gb|AEN01525.1| TetR family transcriptional regulator [Mycobacterium tuberculosis
CTRI-2]
Length=216
Score = 437 bits (1123), Expect = 6e-121, Method: Compositional matrix adjust.
Identities = 215/216 (99%), Positives = 216/216 (100%), Gaps = 0/216 (0%)
Query 1 VTSHAADEKQAAPPMRRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYF 60
+TSHAADEKQAAPPMRRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYF
Sbjct 1 MTSHAADEKQAAPPMRRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYF 60
Query 61 YFDSKYSVLAQILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRA 120
YFDSKYSVLAQILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRA
Sbjct 61 YFDSKYSVLAQILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRA 120
Query 121 CNAARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALM 180
CNAARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALM
Sbjct 121 CNAARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALM 180
Query 181 LTGDALLVGPDSDAARRVRVLEQMWLNALWGGGKAP 216
LTGDALLVGPDSDAARRVRVLEQMWLNALWGGGKAP
Sbjct 181 LTGDALLVGPDSDAARRVRVLEQMWLNALWGGGKAP 216
>gi|340628050|ref|YP_004746502.1| putative transcriptional regulatory protein [Mycobacterium canettii
CIPT 140010059]
gi|340006240|emb|CCC45414.1| putative transcriptional regulatory protein (probably TETR-family)
[Mycobacterium canettii CIPT 140010059]
Length=216
Score = 434 bits (1117), Expect = 3e-120, Method: Compositional matrix adjust.
Identities = 214/216 (99%), Positives = 215/216 (99%), Gaps = 0/216 (0%)
Query 1 VTSHAADEKQAAPPMRRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYF 60
+TSHAADEKQAAPPMRRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYF
Sbjct 1 MTSHAADEKQAAPPMRRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYF 60
Query 61 YFDSKYSVLAQILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRA 120
YFDSKYSVLAQILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRA
Sbjct 61 YFDSKYSVLAQILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRA 120
Query 121 CNAARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALM 180
CNAARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALM
Sbjct 121 CNAARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALM 180
Query 181 LTGDALLVGPDSDAARRVRVLEQMWLNALWGGGKAP 216
LTGDALLVGPDSD ARRVRVLEQMWLNALWGGGKAP
Sbjct 181 LTGDALLVGPDSDPARRVRVLEQMWLNALWGGGKAP 216
>gi|341602982|emb|CCC65660.1| possible transcriptional regulatory protein (probably tetR-family)
[Mycobacterium bovis BCG str. Moreau RDJ]
Length=216
Score = 434 bits (1115), Expect = 6e-120, Method: Compositional matrix adjust.
Identities = 214/216 (99%), Positives = 215/216 (99%), Gaps = 0/216 (0%)
Query 1 VTSHAADEKQAAPPMRRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYF 60
+TSHAADEKQAAPPMRRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYF
Sbjct 1 MTSHAADEKQAAPPMRRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYF 60
Query 61 YFDSKYSVLAQILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRA 120
YFDSKYSVLAQILAEATEELEEASQHFSARQP ESPEQFVNRMIGSVAAVYANNDPVLRA
Sbjct 61 YFDSKYSVLAQILAEATEELEEASQHFSARQPWESPEQFVNRMIGSVAAVYANNDPVLRA 120
Query 121 CNAARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALM 180
CNAARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALM
Sbjct 121 CNAARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALM 180
Query 181 LTGDALLVGPDSDAARRVRVLEQMWLNALWGGGKAP 216
LTGDALLVGPDSDAARRVRVLEQMWLNALWGGGKAP
Sbjct 181 LTGDALLVGPDSDAARRVRVLEQMWLNALWGGGKAP 216
>gi|308406044|ref|ZP_07494903.2| transcriptional regulator, tetR-family [Mycobacterium tuberculosis
SUMu012]
gi|308364711|gb|EFP53562.1| transcriptional regulator, tetR-family [Mycobacterium tuberculosis
SUMu012]
gi|323718290|gb|EGB27468.1| transcriptional regulator [Mycobacterium tuberculosis CDC1551A]
Length=202
Score = 410 bits (1053), Expect = 9e-113, Method: Compositional matrix adjust.
Identities = 202/202 (100%), Positives = 202/202 (100%), Gaps = 0/202 (0%)
Query 15 MRRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYFYFDSKYSVLAQILA 74
MRRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYFYFDSKYSVLAQILA
Sbjct 1 MRRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYFYFDSKYSVLAQILA 60
Query 75 EATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRACNAARQSDMEIRDI 134
EATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRACNAARQSDMEIRDI
Sbjct 61 EATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRACNAARQSDMEIRDI 120
Query 135 LERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALMLTGDALLVGPDSDA 194
LERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALMLTGDALLVGPDSDA
Sbjct 121 LERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALMLTGDALLVGPDSDA 180
Query 195 ARRVRVLEQMWLNALWGGGKAP 216
ARRVRVLEQMWLNALWGGGKAP
Sbjct 181 ARRVRVLEQMWLNALWGGGKAP 202
>gi|118618716|ref|YP_907048.1| TetR family transcriptional regulator [Mycobacterium ulcerans
Agy99]
gi|183981649|ref|YP_001849940.1| TetR family transcriptional regulator [Mycobacterium marinum
M]
gi|118570826|gb|ABL05577.1| transcriptional regulatory protein (TetR- family) [Mycobacterium
ulcerans Agy99]
gi|183174975|gb|ACC40085.1| transcriptional regulatory protein (TetR- family) [Mycobacterium
marinum M]
Length=217
Score = 333 bits (854), Expect = 9e-90, Method: Compositional matrix adjust.
Identities = 159/212 (75%), Positives = 183/212 (87%), Gaps = 0/212 (0%)
Query 1 VTSHAADEKQAAPPMRRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYF 60
V AADEKQ P +RRRGD+ RQAIL+A RELLEE PFAELSV IS RAGVARSGFYF
Sbjct 2 VNGQAADEKQRGPTLRRRGDKQRQAILQAVRELLEERPFAELSVATISNRAGVARSGFYF 61
Query 61 YFDSKYSVLAQILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRA 120
YFDSKYSVLAQ++AEA EELEE +Q+F+ RQPGESP++F RM+GS A VY +NDPV+ A
Sbjct 62 YFDSKYSVLAQLMAEAVEELEERTQYFAPRQPGESPQEFAKRMVGSAAIVYTHNDPVMMA 121
Query 121 CNAARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALM 180
CNAAR +D+EIRDIL++QF V+LRE +GV +AE++AGTA+PISEDLPTL+RTL ATTALM
Sbjct 122 CNAARHTDIEIRDILDQQFDVVLREIVGVIDAEMRAGTANPISEDLPTLIRTLTATTALM 181
Query 181 LTGDALLVGPDSDAARRVRVLEQMWLNALWGG 212
LTGDALLVG DSD RRVRVLEQMWLNALWGG
Sbjct 182 LTGDALLVGRDSDLERRVRVLEQMWLNALWGG 213
>gi|118465113|ref|YP_883088.1| TetR family transcriptional regulator [Mycobacterium avium 104]
gi|118166400|gb|ABK67297.1| transcriptional regulator, TetR family protein [Mycobacterium
avium 104]
Length=211
Score = 310 bits (794), Expect = 9e-83, Method: Compositional matrix adjust.
Identities = 147/212 (70%), Positives = 180/212 (85%), Gaps = 3/212 (1%)
Query 1 VTSHAADEKQAAPPMRRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYF 60
+TSH A+ + P RRRGD+ RQAIL A RELL+E PFAELSV ISLRAGVARSGFYF
Sbjct 1 MTSHPANPE---PGARRRGDKQRQAILAAVRELLQEKPFAELSVSTISLRAGVARSGFYF 57
Query 61 YFDSKYSVLAQILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRA 120
YFDSKY+VLAQ++AEATEELE+ +Q+F+ RQPGESPEQF RM+GS AAVYA+NDPV+ A
Sbjct 58 YFDSKYAVLAQLMAEATEELEQLTQYFAPRQPGESPEQFAKRMVGSAAAVYAHNDPVMTA 117
Query 121 CNAARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALM 180
CN AR +D+EIR+++++QF+V+L + +G+ EAE+KAGTA PIS+DLPTL+RTLA TTALM
Sbjct 118 CNEARHTDVEIRNLMDQQFEVVLAQIVGIVEAEMKAGTARPISDDLPTLIRTLAGTTALM 177
Query 181 LTGDALLVGPDSDAARRVRVLEQMWLNALWGG 212
LTGD +L GPDSD RRV VLEQ+WL+ALW G
Sbjct 178 LTGDPVLTGPDSDRDRRVAVLEQLWLHALWAG 209
>gi|240171830|ref|ZP_04750489.1| TetR family transcriptional regulator [Mycobacterium kansasii
ATCC 12478]
Length=215
Score = 307 bits (786), Expect = 7e-82, Method: Compositional matrix adjust.
Identities = 157/212 (75%), Positives = 184/212 (87%), Gaps = 1/212 (0%)
Query 1 VTSHAADEKQAAPPMRRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYF 60
++ HA D+ QA P +RRRGD+HRQAIL+A RELL+E PFAELSV IS RAGVARSGFYF
Sbjct 1 MSEHAPDQ-QAVPALRRRGDKHRQAILQAVRELLQERPFAELSVSTISNRAGVARSGFYF 59
Query 61 YFDSKYSVLAQILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRA 120
YFDSKY+VLAQILAEA EELEE + +F+ RQPGESP+QF RM+GS A VYA+NDPV+ A
Sbjct 60 YFDSKYAVLAQILAEAAEELEELTHYFAPRQPGESPQQFAKRMVGSAAVVYAHNDPVIVA 119
Query 121 CNAARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALM 180
CNAAR +D+EIR+ILE+QF V+LRE +GV EAE++AGTA+PIS+DLPTL+RTLA TTAL+
Sbjct 120 CNAARHTDIEIREILEQQFDVVLREIVGVVEAEMRAGTANPISDDLPTLIRTLAGTTALV 179
Query 181 LTGDALLVGPDSDAARRVRVLEQMWLNALWGG 212
LTGD LLVG DSD RRVRVLEQMWLNALWGG
Sbjct 180 LTGDPLLVGRDSDPDRRVRVLEQMWLNALWGG 211
>gi|296171146|ref|ZP_06852594.1| TetR family transcriptional regulator [Mycobacterium parascrofulaceum
ATCC BAA-614]
gi|295894282|gb|EFG74037.1| TetR family transcriptional regulator [Mycobacterium parascrofulaceum
ATCC BAA-614]
Length=220
Score = 301 bits (771), Expect = 5e-80, Method: Compositional matrix adjust.
Identities = 143/212 (68%), Positives = 178/212 (84%), Gaps = 3/212 (1%)
Query 1 VTSHAADEKQAAPPMRRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYF 60
++SH A + P +RRGD+ RQAIL+A RELL+E PFAELSV ISLRAGVARSGFYF
Sbjct 10 MSSHPATPE---PGGQRRGDKQRQAILQAVRELLQEKPFAELSVSTISLRAGVARSGFYF 66
Query 61 YFDSKYSVLAQILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRA 120
YFDSKY+VLAQ++AEA ELEE +Q F+ R+PGESPEQF RM+GS AAVYA+NDPV+ A
Sbjct 67 YFDSKYAVLAQLMAEAARELEELTQDFAPREPGESPEQFAQRMVGSAAAVYAHNDPVMTA 126
Query 121 CNAARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALM 180
CN AR +D+EIR+++++QF+V+L + + + EAE+KAGTAHPIS+DLPTL+RTLA TTALM
Sbjct 127 CNEARNTDVEIRNLMDQQFEVVLGQIVAIVEAEMKAGTAHPISDDLPTLIRTLAGTTALM 186
Query 181 LTGDALLVGPDSDAARRVRVLEQMWLNALWGG 212
LTGD +L G DSD RRVRVLE++WL+ALWGG
Sbjct 187 LTGDPILAGRDSDLDRRVRVLERLWLHALWGG 218
>gi|254776345|ref|ZP_05217861.1| transcriptional regulator, TetR family protein [Mycobacterium
avium subsp. avium ATCC 25291]
Length=211
Score = 292 bits (747), Expect = 2e-77, Method: Compositional matrix adjust.
Identities = 148/212 (70%), Positives = 180/212 (85%), Gaps = 3/212 (1%)
Query 1 VTSHAADEKQAAPPMRRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYF 60
+TSH A+ + P RRRGD+ RQAIL A RELL+E PFAELSV ISLRAGVARSGFYF
Sbjct 1 MTSHPANPE---PGARRRGDKQRQAILAAVRELLQEKPFAELSVSTISLRAGVARSGFYF 57
Query 61 YFDSKYSVLAQILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRA 120
YFDSKY+VLAQ++AEATEELEE +Q+F+ RQPGESPEQF RM+GS AAVYA+NDPV+ A
Sbjct 58 YFDSKYAVLAQLMAEATEELEELTQYFAPRQPGESPEQFAKRMVGSAAAVYAHNDPVMTA 117
Query 121 CNAARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALM 180
CN AR +D+EIR+++++QF+V+L + +G+ EAE+KAGTA PIS+DLPTL+RTLA TTALM
Sbjct 118 CNEARHTDVEIRNLMDQQFEVVLAQIVGIVEAEMKAGTARPISDDLPTLIRTLAGTTALM 177
Query 181 LTGDALLVGPDSDAARRVRVLEQMWLNALWGG 212
LTGD +L GPDSD RRV VLEQ+WL+ALW G
Sbjct 178 LTGDPVLTGPDSDRDRRVAVLEQLWLHALWAG 209
>gi|41409206|ref|NP_962042.1| hypothetical protein MAP3108c [Mycobacterium avium subsp. paratuberculosis
K-10]
gi|41398026|gb|AAS05656.1| hypothetical protein MAP_3108c [Mycobacterium avium subsp. paratuberculosis
K-10]
Length=217
Score = 291 bits (746), Expect = 4e-77, Method: Compositional matrix adjust.
Identities = 148/212 (70%), Positives = 179/212 (85%), Gaps = 3/212 (1%)
Query 1 VTSHAADEKQAAPPMRRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYF 60
VTSH A+ + P RRRGD+ RQAIL RELL+E PFAELSV ISLRAGVARSGFYF
Sbjct 7 VTSHPANPE---PGARRRGDKQRQAILAVVRELLQEKPFAELSVSTISLRAGVARSGFYF 63
Query 61 YFDSKYSVLAQILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRA 120
YFDSKY+VLAQ++AEATEELEE +Q+F+ RQPGESPEQF RM+GS AAVYA+NDPV+ A
Sbjct 64 YFDSKYAVLAQLMAEATEELEELTQYFAPRQPGESPEQFAKRMVGSAAAVYAHNDPVMTA 123
Query 121 CNAARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALM 180
CN AR +D+EIR+++++QF+V+L + +G+ EAE+KAGTA PIS+DLPTL+RTLA TTALM
Sbjct 124 CNEARHTDVEIRNLMDQQFEVVLAQIVGIVEAEMKAGTARPISDDLPTLIRTLAGTTALM 183
Query 181 LTGDALLVGPDSDAARRVRVLEQMWLNALWGG 212
LTGD +L GPDSD RRV VLEQ+WL+ALW G
Sbjct 184 LTGDPVLTGPDSDRDRRVAVLEQLWLHALWAG 215
>gi|336459248|gb|EGO38193.1| transcriptional regulator [Mycobacterium avium subsp. paratuberculosis
S397]
Length=211
Score = 291 bits (744), Expect = 6e-77, Method: Compositional matrix adjust.
Identities = 147/212 (70%), Positives = 179/212 (85%), Gaps = 3/212 (1%)
Query 1 VTSHAADEKQAAPPMRRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYF 60
+TSH A+ + P RRRGD+ RQ IL A RELL+E PFAELSV ISLRAGVARSGFYF
Sbjct 1 MTSHPANPE---PGARRRGDKQRQVILAAVRELLQEKPFAELSVSTISLRAGVARSGFYF 57
Query 61 YFDSKYSVLAQILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRA 120
YFDSKY+VLAQ++AEATEELEE +Q+F+ RQPGESPEQF RM+GS AAVYA+NDPV+ A
Sbjct 58 YFDSKYAVLAQLMAEATEELEELTQYFAPRQPGESPEQFAKRMVGSAAAVYAHNDPVMTA 117
Query 121 CNAARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALM 180
CN AR +D+EIR+++++QF+V+L + +G+ EAE+KAGTA PIS+DLPTL+RTLA TTALM
Sbjct 118 CNEARHTDVEIRNLMDQQFEVVLAQIVGIVEAEMKAGTARPISDDLPTLIRTLAGTTALM 177
Query 181 LTGDALLVGPDSDAARRVRVLEQMWLNALWGG 212
LTGD +L GPDSD RRV VLEQ+WL+ALW G
Sbjct 178 LTGDPVLTGPDSDRDRRVAVLEQLWLHALWAG 209
>gi|254820774|ref|ZP_05225775.1| transcriptional regulator, TetR family protein [Mycobacterium
intracellulare ATCC 13950]
Length=211
Score = 278 bits (712), Expect = 3e-73, Method: Compositional matrix adjust.
Identities = 142/212 (67%), Positives = 176/212 (84%), Gaps = 3/212 (1%)
Query 1 VTSHAADEKQAAPPMRRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYF 60
++SH A+ + P RRRGD+ RQAI+ A RELL+E PFAELSV ISLRAGVARSGFYF
Sbjct 1 MSSHPANPE---PGARRRGDKQRQAIVEAVRELLQEKPFAELSVSTISLRAGVARSGFYF 57
Query 61 YFDSKYSVLAQILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRA 120
YFDSKY+VLAQ++AEATEELEE +Q+F+ RQ GESPE+F RM+GS AAVY +NDPV+ A
Sbjct 58 YFDSKYAVLAQLMAEATEELEELTQYFAPRQAGESPEEFAKRMVGSAAAVYEHNDPVVTA 117
Query 121 CNAARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALM 180
CN AR +D+EIRD+L++QF+V+L + + + EAE+KAGTA PIS+DLPTL+RTL TTAL+
Sbjct 118 CNEARHTDVEIRDLLDQQFEVVLAQIVAIVEAEMKAGTARPISDDLPTLIRTLTGTTALV 177
Query 181 LTGDALLVGPDSDAARRVRVLEQMWLNALWGG 212
LTGD +L G DSD RRVRVLEQ+WL+ALW G
Sbjct 178 LTGDPVLTGSDSDRDRRVRVLEQLWLHALWSG 209
>gi|342858091|ref|ZP_08714746.1| TetR family transcriptional regulator [Mycobacterium colombiense
CECT 3035]
gi|342133795|gb|EGT86975.1| TetR family transcriptional regulator [Mycobacterium colombiense
CECT 3035]
Length=211
Score = 266 bits (679), Expect = 2e-69, Method: Compositional matrix adjust.
Identities = 146/212 (69%), Positives = 178/212 (84%), Gaps = 3/212 (1%)
Query 1 VTSHAADEKQAAPPMRRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYF 60
+TSH A + P RRRGD+ RQAIL+A RELL+E PFAELSV ISLRAGVARSGFYF
Sbjct 1 MTSHPATPE---PGARRRGDKQRQAILQAVRELLQEKPFAELSVSTISLRAGVARSGFYF 57
Query 61 YFDSKYSVLAQILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRA 120
YFDSKY+VLAQ++AEA EELEE +++F+ RQ GESPEQF RM+GS AAVYA+NDPV+ A
Sbjct 58 YFDSKYAVLAQLMAEAAEELEELTEYFAPRQAGESPEQFAKRMVGSAAAVYAHNDPVVTA 117
Query 121 CNAARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALM 180
CN AR +D+EIRD+L++QF+V+L + +G+ EAE+KAGTA PIS+DLPTL+RTLA TTAL+
Sbjct 118 CNEARNTDVEIRDLLDQQFEVVLGQIVGIVEAEMKAGTATPISDDLPTLIRTLAGTTALV 177
Query 181 LTGDALLVGPDSDAARRVRVLEQMWLNALWGG 212
LTGD +L G DSD RRVRVLEQ+WL+ALW G
Sbjct 178 LTGDPILTGRDSDRDRRVRVLEQLWLHALWAG 209
>gi|333991432|ref|YP_004524046.1| TetR family transcriptional regulator [Mycobacterium sp. JDM601]
gi|333487400|gb|AEF36792.1| TetR family transcriptional regulator [Mycobacterium sp. JDM601]
Length=218
Score = 264 bits (674), Expect = 7e-69, Method: Compositional matrix adjust.
Identities = 127/199 (64%), Positives = 152/199 (77%), Gaps = 0/199 (0%)
Query 17 RRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYFYFDSKYSVLAQILAEA 76
RRGD+ RQAI++A RELLEE PFAELSV IS RAGVARSGFYFYFDSKY+VLA ILAEA
Sbjct 18 RRGDKQRQAIVQAVRELLEEKPFAELSVSTISDRAGVARSGFYFYFDSKYAVLAHILAEA 77
Query 77 TEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRACNAARQSDMEIRDILE 136
++ELEE +Q+F+ R ESP F RM+GS AAV+A+NDPV+ ACN AR SD EIR++L+
Sbjct 78 SQELEELTQYFAPRGAEESPAAFAERMVGSAAAVFAHNDPVMSACNMARNSDAEIRELLD 137
Query 137 RQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALMLTGDALLVGPDSDAAR 196
Q ++ + +GV E+ AGTA PISED+P LVRTLAATT ML+GD +G D D R
Sbjct 138 AQIDAVIHQIVGVVNDEIAAGTADPISEDIPALVRTLAATTGYMLSGDTAFLGTDGDVGR 197
Query 197 RVRVLEQMWLNALWGGGKA 215
VRVLE +WL ALWGG A
Sbjct 198 GVRVLEALWLTALWGGDAA 216
>gi|118467960|ref|YP_886640.1| TetR family transcriptional regulator [Mycobacterium smegmatis
str. MC2 155]
gi|118473528|ref|YP_885411.1| TetR family transcriptional regulator [Mycobacterium smegmatis
str. MC2 155]
gi|118169247|gb|ABK70143.1| transcriptional regulator, TetR family protein [Mycobacterium
smegmatis str. MC2 155]
gi|118174815|gb|ABK75711.1| transcriptional regulator, TetR family protein [Mycobacterium
smegmatis str. MC2 155]
Length=219
Score = 213 bits (543), Expect = 1e-53, Method: Compositional matrix adjust.
Identities = 117/210 (56%), Positives = 147/210 (70%), Gaps = 3/210 (1%)
Query 3 SHAADEKQAAPPMRRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYFYF 62
S+ + AA R RGDR R+AI+ A RELLEE PFA++SV IS RAGVARSGFYFYF
Sbjct 10 SNGSAGATAAQARRSRGDRQREAIVAAVRELLEEQPFADISVSTISERAGVARSGFYFYF 69
Query 63 DSKYSVLAQILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRACN 122
DSKY+VLA ILAEA EEL+ + +F+ R ESP F RM+GS AAVYA NDPV+ AC
Sbjct 70 DSKYAVLAVILAEAMEELDALTHNFAPRGENESPAAFAKRMVGSAAAVYATNDPVMSACT 129
Query 123 AARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALMLT 182
A+ +D +IRDI+ + + +GV E + A PIS+DLP LVRTL ATTA+ L+
Sbjct 130 VAQNTDAQIRDIMNDFEDATIAKIVGVIEQDTG---ARPISDDLPALVRTLTATTAMTLS 186
Query 183 GDALLVGPDSDAARRVRVLEQMWLNALWGG 212
DA VG D+D AR V ++E++WL+ALWGG
Sbjct 187 RDAGFVGRDADPARAVEIVERLWLSALWGG 216
>gi|120403026|ref|YP_952855.1| TetR family transcriptional regulator [Mycobacterium vanbaalenii
PYR-1]
gi|119955844|gb|ABM12849.1| transcriptional regulator, TetR family [Mycobacterium vanbaalenii
PYR-1]
Length=213
Score = 211 bits (537), Expect = 7e-53, Method: Compositional matrix adjust.
Identities = 106/197 (54%), Positives = 139/197 (71%), Gaps = 3/197 (1%)
Query 16 RRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYFYFDSKYSVLAQILAE 75
R RGDR R AI+ A RELL+E FA+LSV IS RAGVARSGFYFYFDSKY+VLA I+AE
Sbjct 12 RSRGDRQRDAIIAAVRELLQERAFADLSVSTISERAGVARSGFYFYFDSKYAVLAVIVAE 71
Query 76 ATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRACNAARQSDMEIRDIL 135
A EL++ + F+ R+PGESP F RM+G A VYA NDP++ ACN AR +D EIR+I+
Sbjct 72 AMAELDQLTHDFAPREPGESPSDFAKRMVGYAATVYARNDPIMGACNLARNTDAEIREIM 131
Query 136 ERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALMLTGDALLVGPDSDAA 195
+ FQ + + I + + A P+S+DLP LVRTL A T++ L D+ VG +D A
Sbjct 132 D-DFQDSVIDKI--VDLVGRDSGARPVSQDLPALVRTLIAMTSMTLAHDSAFVGRGADPA 188
Query 196 RRVRVLEQMWLNALWGG 212
R V ++E++WL++LWGG
Sbjct 189 RAVEIVERLWLSSLWGG 205
>gi|315445222|ref|YP_004078101.1| TetR family transcriptional regulator [Mycobacterium sp. Spyr1]
gi|315263525|gb|ADU00267.1| transcriptional regulator, TetR family [Mycobacterium sp. Spyr1]
Length=212
Score = 207 bits (526), Expect = 1e-51, Method: Compositional matrix adjust.
Identities = 102/197 (52%), Positives = 136/197 (70%), Gaps = 3/197 (1%)
Query 16 RRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYFYFDSKYSVLAQILAE 75
R RGDR R AI+ A RELL E PFAELSV IS RAGVARSGFYFYFDSKY+VLA I+AE
Sbjct 18 RSRGDRQRDAIVTAVRELLHERPFAELSVSTISERAGVARSGFYFYFDSKYAVLAVIIAE 77
Query 76 ATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRACNAARQSDMEIRDIL 135
A EL++ + F+ R ESP +F RM+G A V+A+NDP++RACN AR +D +IR+I+
Sbjct 78 AMAELDQLTHSFAPRDEAESPSEFAKRMVGYAAIVFASNDPIMRACNLARSTDAQIREIM 137
Query 136 ERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALMLTGDALLVGPDSDAA 195
+ ++ + +G+ + A PIS+DLP LVR + A T+ L D+ VG D D A
Sbjct 138 DDFQNTVVEKIVGLVG---RDAGARPISDDLPALVRVMIAVTSSTLAHDSAFVGRDGDPA 194
Query 196 RRVRVLEQMWLNALWGG 212
R + V+E++W ++LWGG
Sbjct 195 RALAVVERLWESSLWGG 211
>gi|145224893|ref|YP_001135571.1| TetR family transcriptional regulator [Mycobacterium gilvum PYR-GCK]
gi|145217379|gb|ABP46783.1| transcriptional regulator, TetR family [Mycobacterium gilvum
PYR-GCK]
Length=212
Score = 206 bits (525), Expect = 2e-51, Method: Compositional matrix adjust.
Identities = 102/197 (52%), Positives = 135/197 (69%), Gaps = 3/197 (1%)
Query 16 RRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYFYFDSKYSVLAQILAE 75
R RGDR R AI+ A RELL E PFAELSV IS RAGVARSGFYFYFDSKY+VLA I+AE
Sbjct 18 RSRGDRQRDAIVTAVRELLHERPFAELSVSTISERAGVARSGFYFYFDSKYAVLAVIIAE 77
Query 76 ATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRACNAARQSDMEIRDIL 135
A EL++ + F R ESP +F RM+G A V+A+NDP++RACN AR +D +IR+I+
Sbjct 78 AMAELDQLTHSFGPRDEAESPSEFAKRMVGYAAIVFASNDPIMRACNLARSTDAQIREIM 137
Query 136 ERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALMLTGDALLVGPDSDAA 195
+ ++ + +G+ + A PIS+DLP LVR + A T+ L D+ VG D D A
Sbjct 138 DDFQNTVVEKIVGLVG---RDAGARPISDDLPALVRVMIAVTSSTLAHDSAFVGRDGDPA 194
Query 196 RRVRVLEQMWLNALWGG 212
R + V+E++W ++LWGG
Sbjct 195 RALAVVERLWESSLWGG 211
>gi|169630503|ref|YP_001704152.1| TetR family transcriptional regulator [Mycobacterium abscessus
ATCC 19977]
gi|169242470|emb|CAM63498.1| Putative transcriptional regulator, TetR family [Mycobacterium
abscessus]
Length=207
Score = 193 bits (491), Expect = 1e-47, Method: Compositional matrix adjust.
Identities = 98/195 (51%), Positives = 135/195 (70%), Gaps = 1/195 (0%)
Query 18 RGDRHRQAILRAARELLEET-PFAELSVRAISLRAGVARSGFYFYFDSKYSVLAQILAEA 76
RGDR R AI+ A EL+ E FA+LSV AIS RAGV RSGFYFYFDSKYSVLAQ++ +A
Sbjct 12 RGDRQRDAIMTAVAELIAENHSFADLSVSAISERAGVGRSGFYFYFDSKYSVLAQMVGDA 71
Query 77 TEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRACNAARQSDMEIRDILE 136
EL+E + +F+ R E+PEQF +RM+GS AA +A+NDP+++AC AR +D I +L+
Sbjct 72 FAELDELTHYFAPRGEEETPEQFAHRMVGSAAASFAHNDPLMKACQEARITDPTIAGLLD 131
Query 137 RQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALMLTGDALLVGPDSDAAR 196
V++ + + + E EVK A PIS+DLP LVR+L A TA ++GD+ VG ++D AR
Sbjct 132 DLTDVVIEKILKIAETEVKERGAQPISDDLPALVRSLVALTASTVSGDSSFVGRNTDPAR 191
Query 197 RVRVLEQMWLNALWG 211
+ +E +W +L G
Sbjct 192 AIATVETLWRVSLLG 206
>gi|108798777|ref|YP_638974.1| TetR family transcriptional regulator [Mycobacterium sp. MCS]
gi|119867895|ref|YP_937847.1| TetR family transcriptional regulator [Mycobacterium sp. KMS]
gi|126434378|ref|YP_001070069.1| TetR family transcriptional regulator [Mycobacterium sp. JLS]
gi|108769196|gb|ABG07918.1| transcriptional regulator, TetR family [Mycobacterium sp. MCS]
gi|119693984|gb|ABL91057.1| transcriptional regulator, TetR family [Mycobacterium sp. KMS]
gi|126234178|gb|ABN97578.1| transcriptional regulator, TetR family [Mycobacterium sp. JLS]
Length=211
Score = 192 bits (489), Expect = 2e-47, Method: Compositional matrix adjust.
Identities = 108/205 (53%), Positives = 143/205 (70%), Gaps = 4/205 (1%)
Query 9 KQAAPPMRR-RGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYFYFDSKYS 67
+ A P +RR RGDR R AI+ A RELL+E PFA+LSV IS RAGVARSGFYFYFDSKY+
Sbjct 4 ESATPEIRRSRGDRQRDAIVAAVRELLQEQPFADLSVSTISERAGVARSGFYFYFDSKYA 63
Query 68 VLAQILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRACNAARQS 127
VLA I+A+A EL++ + F+ R ESP F RM+G AAV+A+N+P++RA AR +
Sbjct 64 VLAVIVADAMAELDKLTHDFAPRDADESPATFARRMVGYAAAVFASNNPIMRATTLARNT 123
Query 128 DMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALMLTGDALL 187
D +IR+I+ ++ + +G+ + A PIS+DLP LVRTL ATTAL L+ D+
Sbjct 124 DAQIREIMNDFEDTVIDKIVGLVRQD---DGARPISDDLPALVRTLTATTALTLSHDSGF 180
Query 188 VGPDSDAARRVRVLEQMWLNALWGG 212
VG +D AR V V+E++WL ALWGG
Sbjct 181 VGRGADPARAVEVVERLWLYALWGG 205
>gi|111026296|ref|YP_708579.1| TetR family transcriptional regulator [Rhodococcus jostii RHA1]
gi|110825139|gb|ABH00421.1| transcriptional regulator, TetR family [Rhodococcus jostii RHA1]
Length=247
Score = 84.7 bits (208), Expect = 8e-15, Method: Compositional matrix adjust.
Identities = 62/198 (32%), Positives = 98/198 (50%), Gaps = 9/198 (4%)
Query 18 RGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYFYFDSKYSVLAQILAEAT 77
+GDR QAIL A E+L P +S+ ++ RAG++RS FYFYF+SK+ VL+ +L+ T
Sbjct 45 KGDRREQAILEGAYEILRTEPLRNVSIDDLAKRAGLSRSSFYFYFESKWQVLSALLSSVT 104
Query 78 EELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRACNAARQSDMEIRDILER 137
++ AS R PG SPE + + V V+ + VLR A ++ L
Sbjct 105 ADVFTASAMIFERPPGISPEAAIEHAVSEVMVVWERHGHVLREVGDAAAAE----PTLGA 160
Query 138 QFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALMLTGDALLVGPDSDAARR 197
Q+ +L + A ++ A ++ D P R+LAA M + L+ S+ A R
Sbjct 161 QWDKILGRFVDAAAAAIERDRAAGVALDGPP-ARSLAAALIWMGERNLGLMSMRSENAIR 219
Query 198 ----VRVLEQMWLNALWG 211
V + +WL ++G
Sbjct 220 TEDMVETVTTVWLRTVFG 237
>gi|312141723|ref|YP_004009059.1| tetr family transcriptional regulator [Rhodococcus equi 103S]
gi|311891062|emb|CBH50381.1| putative TetR family transcriptional regulator [Rhodococcus equi
103S]
Length=211
Score = 82.0 bits (201), Expect = 6e-14, Method: Compositional matrix adjust.
Identities = 61/214 (29%), Positives = 103/214 (49%), Gaps = 9/214 (4%)
Query 1 VTSHAADEKQAAPPMRRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYF 60
++SH A + +G+ R AIL A LLE+ E+++ IS AGV RSGFYF
Sbjct 1 MSSHPASSDETRTRRANKGEERRAAILDAVERLLEDRTLDEINISDISRAAGVTRSGFYF 60
Query 61 YFDSKYSVLAQILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRA 120
YFD+K +A + E++E ++ + AR+ SP + ++ +I V + + + RA
Sbjct 61 YFDNKAKAVAALSRTVYGEMQEGARGYLAREG--SPREMIDGLITEVIGTWERHPNLYRA 118
Query 121 CNAARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTA--HPISEDLPTLVRTLAATTA 178
AR SD +R++ + + V +AE +G A P S L ++ +
Sbjct 119 LRDARDSDPTVREMWDHDRFSFVDPVASVIDAERTSGRAADGPDSRALAVVLLDMNDRAV 178
Query 179 LMLTGDALLVGPDSDAARRVR-VLEQMWLNALWG 211
L+ GP++ R L +WLN+++G
Sbjct 179 ESLSRG----GPEALTPETAREALVAVWLNSIYG 208
>gi|325673017|ref|ZP_08152711.1| transcriptional regulator [Rhodococcus equi ATCC 33707]
gi|325556270|gb|EGD25938.1| transcriptional regulator [Rhodococcus equi ATCC 33707]
Length=229
Score = 81.6 bits (200), Expect = 6e-14, Method: Compositional matrix adjust.
Identities = 61/214 (29%), Positives = 103/214 (49%), Gaps = 9/214 (4%)
Query 1 VTSHAADEKQAAPPMRRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYF 60
++SH A + +G+ R AIL A LLE+ E+++ IS AGV RSGFYF
Sbjct 19 MSSHPASSDETRTRRANKGEERRAAILDAVERLLEDRTLDEINISDISRAAGVTRSGFYF 78
Query 61 YFDSKYSVLAQILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRA 120
YFD+K +A + E++E ++ + AR+ SP + ++ +I V + + + RA
Sbjct 79 YFDNKAKAVAALSRTVYGEMQEGARGYLAREG--SPREMIDGLITEVIGTWERHPNLYRA 136
Query 121 CNAARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTA--HPISEDLPTLVRTLAATTA 178
AR SD +R++ + + V +AE +G A P S L ++ +
Sbjct 137 LRDARDSDPTVREMWDHDRFSFVDPVASVIDAERTSGRAADGPDSRALAVVLLDMNDRAV 196
Query 179 LMLTGDALLVGPDSDAARRVR-VLEQMWLNALWG 211
L+ GP++ R L +WLN+++G
Sbjct 197 ESLS----RGGPEALTPETAREALVAVWLNSIYG 226
>gi|302867732|ref|YP_003836369.1| regulatory protein TetR [Micromonospora aurantiaca ATCC 27029]
gi|315505866|ref|YP_004084753.1| regulatory protein TetR [Micromonospora sp. L5]
gi|302570591|gb|ADL46793.1| regulatory protein TetR [Micromonospora aurantiaca ATCC 27029]
gi|315412485|gb|ADU10602.1| regulatory protein TetR [Micromonospora sp. L5]
Length=226
Score = 75.5 bits (184), Expect = 5e-12, Method: Compositional matrix adjust.
Identities = 65/213 (31%), Positives = 93/213 (44%), Gaps = 11/213 (5%)
Query 11 AAPPMRRR-----GDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYFYFDSK 65
AAP RR GD AIL A LL E PFA++S+ ++ AG++R FYFYF SK
Sbjct 10 AAPTRGRRAGRSTGDDRETAILATAERLLAERPFADISIDDLARGAGISRPTFYFYFPSK 69
Query 66 YSVLAQILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRACNAAR 125
+VL +L TEE + A+ R E P +I A + + V+ AC R
Sbjct 70 DAVLLTLLDRVTEEADAAAGGVFERL-AEDPRAHWRELIARFHATFGGHRDVVLACAQVR 128
Query 126 QSDMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALMLTGDA 185
++ E+R + + +R E+E G A + LP +A + A
Sbjct 129 GTNAEVRRLWAEVLERWVRAVQAAIESERARGAA---PDGLPARDLAIALNSMNERVWYA 185
Query 186 LLVGPDSDAARR--VRVLEQMWLNALWGGGKAP 216
G A R V VL +WL A++ P
Sbjct 186 TFAGDGPAVAERDVVDVLLDVWLTAIYRTATPP 218
>gi|56966246|pdb|1U9O|A Chain A, Crystal Structure Of The Transcriptional Regulator Ethr
In A Ligand Bound Conformation
gi|56966247|pdb|1U9O|B Chain B, Crystal Structure Of The Transcriptional Regulator Ethr
In A Ligand Bound Conformation
Length=236
Score = 75.1 bits (183), Expect = 7e-12, Method: Compositional matrix adjust.
Identities = 70/226 (31%), Positives = 104/226 (47%), Gaps = 28/226 (12%)
Query 1 VTSHAADEKQAAPPMRRR-----GDRHRQAILRAARELLEETPFAELSVRAISLRAGVAR 55
VT+ AA QA+ P RR GD AIL A LLE+ P A++SV ++ AG++R
Sbjct 21 VTTSAA--SQASLPRGRRTARPSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISR 78
Query 56 SGFYFYFDSKYSVLAQILAEATEELEEASQHFSARQPGESPEQFVNRM-IGSVAAVYANN 114
FYFYF SK +VL +L + + A Q A P ++ + + R I + ++
Sbjct 79 PTFYFYFPSKEAVLLTLLDRVVNQADMALQTL-AENPADTDRENMWRTGINVFFETFGSH 137
Query 115 DPVLRACNAARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLA 174
V RA AAR + +E+ ++ Q + T V +AE G A RTL
Sbjct 138 KAVTRAGQAARATSVEVAELWSTFMQKWIAYTAAVIDAERDRGAAP----------RTLP 187
Query 175 A---TTALMLTGDALLVG------PDSDAARRVRVLEQMWLNALWG 211
A TAL L + L P AR + L +W+ +++G
Sbjct 188 AHELATALNLMNERTLFASFAGEQPSVPEARVLDTLVHIWVTSIYG 233
>gi|56966245|pdb|1U9N|A Chain A, Crystal Structure Of The Transcriptional Regulator Ethr
In A Ligand Bound Conformation Opens Therapeutic Perspectives
Against Tuberculosis And Leprosy
Length=236
Score = 73.9 bits (180), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 70/226 (31%), Positives = 103/226 (46%), Gaps = 28/226 (12%)
Query 1 VTSHAADEKQAAPPMRRR-----GDRHRQAILRAARELLEETPFAELSVRAISLRAGVAR 55
VT+ AA QA+ P RR GD AIL A LLE+ P A++SV ++ AG++R
Sbjct 21 VTTSAA--SQASLPRGRRTARPSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISR 78
Query 56 SGFYFYFDSKYSVLAQILAEATEELEEASQHFSARQPGESPEQFVNRM-IGSVAAVYANN 114
FYFYF SK +VL +L + + A Q A P ++ + R I + ++
Sbjct 79 PTFYFYFPSKEAVLLTLLDRVVNQADXALQTL-AENPADTDRENXWRTGINVFFETFGSH 137
Query 115 DPVLRACNAARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLA 174
V RA AAR + +E+ ++ Q + T V +AE G A RTL
Sbjct 138 KAVTRAGQAARATSVEVAELWSTFXQKWIAYTAAVIDAERDRGAAP----------RTLP 187
Query 175 A---TTALMLTGDALLVG------PDSDAARRVRVLEQMWLNALWG 211
A TAL L + L P AR + L +W+ +++G
Sbjct 188 AHELATALNLXNERTLFASFAGEQPSVPEARVLDTLVHIWVTSIYG 233
>gi|317457508|gb|ADV29775.1| transcriptional regulatory repressor protein EthR [Mycobacterium
tuberculosis]
Length=216
Score = 73.9 bits (180), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 69/229 (31%), Positives = 106/229 (47%), Gaps = 28/229 (12%)
Query 1 VTSHAADEKQAAPPMRRR-----GDRHRQAILRAARELLEETPFAELSVRAISLRAGVAR 55
+T+ AA QA+ P RR GD AIL A LLE+ P A++SV ++ AG++R
Sbjct 1 MTTSAA--SQASLPRGRRTARPSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISR 58
Query 56 SGFYFYFDSKYSVLAQILAEATEELEEASQHFSARQPGESPEQFVNRM-IGSVAAVYANN 114
FYFYF SK +VL +L + + A Q A P ++ + + R I + + ++
Sbjct 59 PTFYFYFPSKEAVLLTLLDRVVNQADMALQTL-AENPADTDRENMWRTGINVLFETFGSH 117
Query 115 DPVLRACNAARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLA 174
V RA AAR + +E+ ++ Q + T V +AE G A RTL
Sbjct 118 KAVTRAGQAARATSVEVAELWSTFMQKWIAYTAAVIDAERDRGAAP----------RTLP 167
Query 175 A---TTALMLTGDALLVG------PDSDAARRVRVLEQMWLNALWGGGK 214
A TAL L + L P AR + L +W+ +++G +
Sbjct 168 AHELATALNLMNERTLFASFAGEQPSVPEARVLDTLVHIWVTSIYGENR 216
>gi|254574835|pdb|3G1M|A Chain A, Ethr From Mycobacterium Tuberculosis In Complex With
Compound Bdm31381
gi|305677856|pdb|3O8G|A Chain A, Ethr From Mycobacterium Tuberculosis In Complex With
Compound Bdm14801
gi|305677857|pdb|3O8H|A Chain A, Ethr From Mycobacterium Tuberculosis In Complex With
Compound Bdm14950
Length=236
Score = 73.6 bits (179), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 69/226 (31%), Positives = 104/226 (47%), Gaps = 28/226 (12%)
Query 1 VTSHAADEKQAAPPMRRR-----GDRHRQAILRAARELLEETPFAELSVRAISLRAGVAR 55
+T+ AA QA+ P RR GD AIL A LLE+ P A++SV ++ AG++R
Sbjct 21 MTTSAA--SQASLPRGRRTARPSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISR 78
Query 56 SGFYFYFDSKYSVLAQILAEATEELEEASQHFSARQPGESPEQFVNRM-IGSVAAVYANN 114
FYFYF SK +VL +L + + A Q A P ++ + + R I + ++
Sbjct 79 PTFYFYFPSKEAVLLTLLDRVVNQADMALQTL-AENPADTDRENMWRTGINVFFETFGSH 137
Query 115 DPVLRACNAARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLA 174
V RA AAR + +E+ ++ Q + T V +AE G A RTL
Sbjct 138 KAVTRAGQAARATSVEVAELWSTFMQKWIAYTAAVIDAERDRGAAP----------RTLP 187
Query 175 A---TTALMLTGDALLVG------PDSDAARRVRVLEQMWLNALWG 211
A TAL L + L P AR + L +W+ +++G
Sbjct 188 AHELATALNLMNERTLFASFAGEQPSVPEARVLDTLVHIWVTSIYG 233
>gi|254574836|pdb|3G1O|A Chain A, Ethr From Mycobacterium Tuberculosis In Complex With
Compound Bdm14500
Length=255
Score = 73.6 bits (179), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 67/225 (30%), Positives = 99/225 (44%), Gaps = 26/225 (11%)
Query 1 VTSHAADEKQAAPPMRRR-----GDRHRQAILRAARELLEETPFAELSVRAISLRAGVAR 55
+T+ AA QA+ P RR GD AIL A LLE+ P A++SV ++ AG++R
Sbjct 20 MTTSAA--SQASLPRGRRTARPSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISR 77
Query 56 SGFYFYFDSKYSVLAQILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANND 115
FYFYF SK +VL +L + + A Q + E I + ++
Sbjct 78 PTFYFYFPSKEAVLLTLLDRVVNQADMALQTLAENPADTDRENMWRTGINVFFETFGSHK 137
Query 116 PVLRACNAARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAA 175
V RA AAR + +E+ ++ Q + T V +AE G A RTL A
Sbjct 138 AVTRAGQAARATSVEVAELWSTFMQKWIAYTAAVIDAERDRGAAP----------RTLPA 187
Query 176 ---TTALMLTGDALLVG------PDSDAARRVRVLEQMWLNALWG 211
TAL L + L P AR + L +W+ +++G
Sbjct 188 HELATALNLMNERTLFASFAGEQPSVPEARVLDTLVHIWVTSIYG 232
>gi|317457510|gb|ADV29776.1| transcriptional regulatory repressor protein EthR [Mycobacterium
tuberculosis]
Length=216
Score = 73.6 bits (179), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 67/228 (30%), Positives = 100/228 (44%), Gaps = 26/228 (11%)
Query 1 VTSHAADEKQAAPPMRRR-----GDRHRQAILRAARELLEETPFAELSVRAISLRAGVAR 55
+T+ AA QA+ P RR GD AIL A LLE+ P A++SV ++ AG++R
Sbjct 1 MTTSAA--SQASLPRGRRTARPSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISR 58
Query 56 SGFYFYFDSKYSVLAQILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANND 115
FYFYF SK +VL +L + + A Q + E I + ++
Sbjct 59 PTFYFYFPSKEAVLLTLLDRVVNQADMALQTLAENPTDTDRENMWRTGINVFFETFGSHK 118
Query 116 PVLRACNAARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAA 175
V RA AAR + +E+ ++ Q + T V +AE G A RTL A
Sbjct 119 AVTRAGQAARATSVEVAELWSTFMQKWIAYTAAVIDAERDRGAAP----------RTLPA 168
Query 176 ---TTALMLTGDALLVG------PDSDAARRVRVLEQMWLNALWGGGK 214
TAL L + L P AR + L +W+ +++G +
Sbjct 169 HELATALNLMNERTLFASFAGEQPSVPEARVLDTLVHIWVTSIYGENR 216
>gi|254574834|pdb|3G1L|A Chain A, Ethr From Mycobacterium Tuberculosis In Complex With
Compound Bdm14744
Length=256
Score = 73.6 bits (179), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 69/226 (31%), Positives = 104/226 (47%), Gaps = 28/226 (12%)
Query 1 VTSHAADEKQAAPPMRRR-----GDRHRQAILRAARELLEETPFAELSVRAISLRAGVAR 55
+T+ AA QA+ P RR GD AIL A LLE+ P A++SV ++ AG++R
Sbjct 21 MTTSAA--SQASLPRGRRTARPSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISR 78
Query 56 SGFYFYFDSKYSVLAQILAEATEELEEASQHFSARQPGESPEQFVNRM-IGSVAAVYANN 114
FYFYF SK +VL +L + + A Q A P ++ + + R I + ++
Sbjct 79 PTFYFYFPSKEAVLLTLLDRVVNQADMALQTL-AENPADTDRENMWRTGINVFFETFGSH 137
Query 115 DPVLRACNAARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLA 174
V RA AAR + +E+ ++ Q + T V +AE G A RTL
Sbjct 138 KAVTRAGQAARATSVEVAELWSTFMQKWIAYTAAVIDAERDRGAAP----------RTLP 187
Query 175 A---TTALMLTGDALLVG------PDSDAARRVRVLEQMWLNALWG 211
A TAL L + L P AR + L +W+ +++G
Sbjct 188 AHELATALNLMNERTLFASFAGEQPSVPEARVLDTLVHIWVTSIYG 233
>gi|15610991|ref|NP_218372.1| transcriptional regulatory repressor protein (TETR-family) ETHR
[Mycobacterium tuberculosis H37Rv]
gi|15843486|ref|NP_338523.1| TetR family transcriptional regulator [Mycobacterium tuberculosis
CDC1551]
gi|31795029|ref|NP_857522.1| transcriptional regulatory repressor protein (TETR-family) ETHR
[Mycobacterium bovis AF2122/97]
83 more sequence titles
Length=216
Score = 73.6 bits (179), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 69/229 (31%), Positives = 105/229 (46%), Gaps = 28/229 (12%)
Query 1 VTSHAADEKQAAPPMRRR-----GDRHRQAILRAARELLEETPFAELSVRAISLRAGVAR 55
+T+ AA QA+ P RR GD AIL A LLE+ P A++SV ++ AG++R
Sbjct 1 MTTSAA--SQASLPRGRRTARPSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISR 58
Query 56 SGFYFYFDSKYSVLAQILAEATEELEEASQHFSARQPGESPEQFVNRM-IGSVAAVYANN 114
FYFYF SK +VL +L + + A Q A P ++ + + R I + ++
Sbjct 59 PTFYFYFPSKEAVLLTLLDRVVNQADMALQTL-AENPADTDRENMWRTGINVFFETFGSH 117
Query 115 DPVLRACNAARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLA 174
V RA AAR + +E+ ++ Q + T V +AE G A RTL
Sbjct 118 KAVTRAGQAARATSVEVAELWSTFMQKWIAYTAAVIDAERDRGAAP----------RTLP 167
Query 175 A---TTALMLTGDALLVG------PDSDAARRVRVLEQMWLNALWGGGK 214
A TAL L + L P AR + L +W+ +++G +
Sbjct 168 AHELATALNLMNERTLFASFAGEQPSVPEARVLDTLVHIWVTSIYGENR 216
>gi|240168331|ref|ZP_04746990.1| transcriptional regulatory repressor protein [Mycobacterium kansasii
ATCC 12478]
Length=215
Score = 73.2 bits (178), Expect = 3e-11, Method: Compositional matrix adjust.
Identities = 59/204 (29%), Positives = 90/204 (45%), Gaps = 14/204 (6%)
Query 16 RRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYFYFDSKYSVLAQILAE 75
R GD AIL A +LL++ P A++SV ++ AG++R FYFYF SK +VL +L
Sbjct 19 RPSGDDRELAILVTAEKLLKDRPLADISVDDLAKGAGISRPTFYFYFPSKEAVLLTLLDR 78
Query 76 ATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRACNAARQSDMEIRDIL 135
E + A ++ + P + I + ++ V RA AAR + E+R +
Sbjct 79 VVTEADTALENL-IQAPDADRDTMWRTGINVFFETFGSHKAVTRAGQAARATSAEVRHLW 137
Query 136 ERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALMLTGDALLVG------ 189
Q + T V E E G A P V L TAL L + L
Sbjct 138 STFMQKWISYTAEVIETERDRGAA-------PVTVPALELATALNLMNERTLFASFAAEQ 190
Query 190 PDSDAARRVRVLEQMWLNALWGGG 213
P A + L +W+++++G G
Sbjct 191 PCVPEAHVLDTLVHIWVSSIYGEG 214
>gi|296165492|ref|ZP_06848024.1| TetR family transcriptional regulator [Mycobacterium parascrofulaceum
ATCC BAA-614]
gi|295899160|gb|EFG78634.1| TetR family transcriptional regulator [Mycobacterium parascrofulaceum
ATCC BAA-614]
Length=212
Score = 72.0 bits (175), Expect = 6e-11, Method: Compositional matrix adjust.
Identities = 51/151 (34%), Positives = 77/151 (51%), Gaps = 5/151 (3%)
Query 26 ILRAARELLEETPFAELSVRAISLRAGVARSGFYFYFDSKYSVLAQILAEATEELEEASQ 85
IL A LL ++SV I A V+R+ FYFYF SK+SV++ +L A E++ + Q
Sbjct 26 ILAATTRLLARQSLTDISVAQILTEAKVSRATFYFYFASKFSVVSGLLERAMEDIFQTVQ 85
Query 86 HFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRACNAARQSDMEIRDILERQFQVLLRE 145
F AR P +SP + R I +V + + PV +A N ++ E+RD+ + +
Sbjct 86 PFLARSPEDSPTVALERSIRAVTRAWHRHRPVFQATNHHWHAEPELRDLWLAIAERFISA 145
Query 146 TIGVFEAEVKAGTAHPISEDLPTLVRTLAAT 176
E E AG I+ +P+ R LAAT
Sbjct 146 GAAEIERERAAGM---ITSPIPS--RMLAAT 171
>gi|169628081|ref|YP_001701730.1| TetR family transcriptional regulator [Mycobacterium abscessus
ATCC 19977]
gi|169240048|emb|CAM61076.1| Putative transcriptional regulator, TetR family [Mycobacterium
abscessus]
Length=212
Score = 71.6 bits (174), Expect = 6e-11, Method: Compositional matrix adjust.
Identities = 62/205 (31%), Positives = 95/205 (47%), Gaps = 18/205 (8%)
Query 16 RRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYFYFDSKYSVLAQILAE 75
R GD QAIL A ELL + P A++SV ++ AG++R FYFYF SK SVL L
Sbjct 13 RPSGDERIQAILATAEELLGKRPLADVSVDDLARGAGISRPTFYFYFSSKESVL---LTL 69
Query 76 ATEELEEASQHFSARQPG--ESPEQFVNRMIGSVAAVYANNDPVLRACNAARQSDMEIRD 133
A +EEA + ++ P SP Q+ +I + + ++ + A ++ + + E+
Sbjct 70 AERIIEEADANVASIDPAAMTSPAQYWRAVIKAYFDAFGSHRALTVALSSMQGTSPELDQ 129
Query 134 ILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALMLTGDALLVG---- 189
+ + T EAE G A P++V AL L A++
Sbjct 130 RWSEVTENWVANTTVGIEAERARGAA-------PSVVPARDIAIALNLINQAMMRATFTG 182
Query 190 --PDSDAARRVRVLEQMWLNALWGG 212
P D + V L +WLNA++GG
Sbjct 183 QQPAVDDGKVVDTLLHVWLNAIYGG 207
>gi|183985374|ref|YP_001853665.1| TetR family transcriptional regulator [Mycobacterium marinum
M]
gi|183178700|gb|ACC43810.1| transcriptional regulatory repressor protein (TetR-family) EthR
[Mycobacterium marinum M]
Length=216
Score = 70.1 bits (170), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 61/212 (29%), Positives = 95/212 (45%), Gaps = 15/212 (7%)
Query 9 KQAAPPMRRR-----GDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYFYFD 63
QA+P RR GD AIL A +LLE+ P ++SV ++ AG++R FYFYF
Sbjct 8 SQASPSRGRRSARPSGDERELAILNTAEKLLEDRPMVDISVDDLAKGAGISRPTFYFYFP 67
Query 64 SKYSVLAQILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRACNA 123
SK +VL +L E + A + A+ P I + ++ V++
Sbjct 68 SKEAVLLTLLDRVVNEADAALDNL-AQAPDVDHVTMWRNGINVFFETFGSHRAVVQGGQG 126
Query 124 ARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALM--- 180
R E+R++ Q + T + EAE + G A P++ LP L LA LM
Sbjct 127 VRSISAEVRELWSTFMQKWIAYTAKIIEAERERGAA-PVT--LPAL--ELATALNLMNER 181
Query 181 -LTGDALLVGPDSDAARRVRVLEQMWLNALWG 211
L+ L P V L +W+++++G
Sbjct 182 TLSASFLAEEPSVPETHVVDTLVHIWVSSIYG 213
>gi|342860108|ref|ZP_08716760.1| TetR family transcriptional regulator [Mycobacterium colombiense
CECT 3035]
gi|342132486|gb|EGT85715.1| TetR family transcriptional regulator [Mycobacterium colombiense
CECT 3035]
Length=213
Score = 69.7 bits (169), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 59/204 (29%), Positives = 94/204 (47%), Gaps = 16/204 (7%)
Query 15 MRRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYFYFDSKYSVLAQIL- 73
+R GD QAIL A LLEE A++SV ++ AG++R FYFYF SK +VL +L
Sbjct 16 IRPTGDEREQAILATAERLLEERSLADISVDDLAKGAGISRPTFYFYFKSKEAVLLSLLE 75
Query 74 ---AEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRACNAARQSDME 130
A A E + A A P + I + ++ + V R A + E
Sbjct 76 PVIARADSEFDGAVHRLPA-----DPRRVWRNGIKAFFTAFSTHRAVARTATEALATSTE 130
Query 131 IRDILERQFQVLLRETIGVFEAEVKAGTA--HPISEDLPTLVRTLAATTAL-MLTGDALL 187
+R + Q + +T + AE G A + + DL T + + T + L+ +
Sbjct 131 LRSLWSGYMQKWIDQTAAMITAERARGAAPDNIPAADLATSLNQMNERTMMAALSAET-- 188
Query 188 VGPDSDAARRVRVLEQMWLNALWG 211
P +AAR V L +W+++++G
Sbjct 189 --PAVEAARVVDTLTHIWISSIYG 210
>gi|298246923|ref|ZP_06970728.1| transcriptional regulator, TetR family [Ktedonobacter racemifer
DSM 44963]
gi|297549582|gb|EFH83448.1| transcriptional regulator, TetR family [Ktedonobacter racemifer
DSM 44963]
Length=220
Score = 69.3 bits (168), Expect = 4e-10, Method: Compositional matrix adjust.
Identities = 55/190 (29%), Positives = 89/190 (47%), Gaps = 1/190 (0%)
Query 23 RQAILRAARELLEETPFAELSVRAISLRAGVARSGFYFYFDSKYSVLAQILAEATEELEE 82
R+AIL A +LL F ELSV I A V+R+ FYFYF+SKY VL +++ + +
Sbjct 24 RKAILDATEQLLAHQRFDELSVADILSSAQVSRASFYFYFESKYVVLGELVRRVVNQAQV 83
Query 83 ASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRACNAARQSDMEIRDILERQFQVL 142
A+ + + ESPEQ + + ++ + PVLRA +SD + + +
Sbjct 84 AAGPW-VEEDIESPEQTLRQGTSQGLQLWIQHAPVLRAIVENWRSDERLAALWMEMMEGF 142
Query 143 LRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALMLTGDALLVGPDSDAARRVRVLE 202
+ E + G A S D TL TL + + A+ D + + VL
Sbjct 143 TQAATHRIERDRATGRAPRTSVDASTLASTLTWMSERIYYLAAIGHPAFHDEQQVIDVLT 202
Query 203 QMWLNALWGG 212
++WL+ ++ G
Sbjct 203 EVWLSVIYNG 212
>gi|254773230|ref|ZP_05214746.1| hypothetical protein MaviaA2_00911 [Mycobacterium avium subsp.
avium ATCC 25291]
Length=213
Score = 68.6 bits (166), Expect = 6e-10, Method: Compositional matrix adjust.
Identities = 60/204 (30%), Positives = 97/204 (48%), Gaps = 16/204 (7%)
Query 15 MRRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYFYFDSK----YSVLA 70
+R GD QAIL A LLE PFA +SV ++ AG++R FYFYF SK S+L
Sbjct 16 IRPTGDEREQAILATAERLLETRPFAGISVDDLAKGAGLSRPTFYFYFKSKEAVVLSLLE 75
Query 71 QILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRACNAARQSDME 130
++A A E + A Q R P + P + I + ++++ + RA A + E
Sbjct 76 PVIARADAEFDGAVQ----RLPTD-PRRVWRNGIKAFFTAFSSHRALARAATEALATSSE 130
Query 131 IRDILERQFQVLLRETIGVFEAEVKAGTAHPI--SEDLPTLVRTLAATTAL-MLTGDALL 187
+R + Q + +T + AE + G A + DL T + + T + L+ +
Sbjct 131 LRSVWSGFMQKWIDQTAAMITAERERGAAPDTIPAADLATSLNQMNERTMMAALSAETPA 190
Query 188 VGPDSDAARRVRVLEQMWLNALWG 211
V D R V L +W+++++G
Sbjct 191 VAED----RVVDTLTHIWVSSIYG 210
>gi|118620041|ref|YP_908373.1| TetR family transcriptional regulator [Mycobacterium ulcerans
Agy99]
gi|118572151|gb|ABL06902.1| transcriptional regulatory repressor protein (TetR-family) EthR
[Mycobacterium ulcerans Agy99]
Length=215
Score = 68.6 bits (166), Expect = 6e-10, Method: Compositional matrix adjust.
Identities = 57/203 (29%), Positives = 91/203 (45%), Gaps = 10/203 (4%)
Query 16 RRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYFYFDSKYSVLAQILAE 75
R GD AIL A +LLE+ P ++SV ++ AG++R FYFYF SK +VL +L
Sbjct 19 RPSGDERELAILNTAEKLLEDRPMVDISVDDLAKGAGISRPTFYFYFPSKEAVLLTLLDR 78
Query 76 ATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRACNAARQSDMEIRDIL 135
E + A + A+ P I + ++ V++ R E+R++
Sbjct 79 VVNEADAALDNL-AQAPDVDHVTMWRNGINVFFETFGSHRAVVQGGQGVRSISTEVRELW 137
Query 136 ERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALM----LTGDALLVGPD 191
Q + T + EAE + G A P++ LP L LA LM L+ L P
Sbjct 138 STFMQKWIAYTAKIIEAERERGAA-PVT--LPAL--ELATALNLMNERTLSASFLAEEPS 192
Query 192 SDAARRVRVLEQMWLNALWGGGK 214
V L +W+++++G +
Sbjct 193 VPETHVVDTLVHVWVSSIYGAAR 215
>gi|256393334|ref|YP_003114898.1| TetR family transcriptional regulator [Catenulispora acidiphila
DSM 44928]
gi|256359560|gb|ACU73057.1| transcriptional regulator, TetR family [Catenulispora acidiphila
DSM 44928]
Length=302
Score = 68.6 bits (166), Expect = 7e-10, Method: Compositional matrix adjust.
Identities = 51/131 (39%), Positives = 68/131 (52%), Gaps = 8/131 (6%)
Query 10 QAAPPMRRRG-----DRH-RQAILRAARELLEETPFAELSVRAISLRAGVARSGFYFYFD 63
+A PP R G DR R+AIL A R LL+E F ELSV I AGVAR FYFYF
Sbjct 12 EATPPRRTAGRAGRDDREVREAILVATRRLLDERRFDELSVADILTAAGVARGSFYFYFA 71
Query 64 SKYSVLAQILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRACNA 123
K VLA++ A EA++ + A + P + + I A ++ PVLRA
Sbjct 72 GKNQVLAELTRRAVALGHEAAEPWLAST--DDPRETIRHGISEGAKLWRAEAPVLRAMVE 129
Query 124 ARQSDMEIRDI 134
+SD E+ ++
Sbjct 130 NWRSDEELGEL 140
>gi|118462741|ref|YP_879467.1| TetR family transcriptional regulator [Mycobacterium avium 104]
gi|118164028|gb|ABK64925.1| transcriptional regulator, TetR family protein [Mycobacterium
avium 104]
Length=213
Score = 67.8 bits (164), Expect = 9e-10, Method: Compositional matrix adjust.
Identities = 60/204 (30%), Positives = 97/204 (48%), Gaps = 16/204 (7%)
Query 15 MRRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYFYFDSK----YSVLA 70
+R GD QAIL A LLE PFA +SV ++ AG++R FYFYF SK S+L
Sbjct 16 IRPTGDEREQAILATALRLLETRPFAGISVDDLAKGAGLSRPTFYFYFKSKEAVVLSLLE 75
Query 71 QILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRACNAARQSDME 130
++A A E + A Q R P + P + I + ++++ + RA A + E
Sbjct 76 PVIARADAEFDGAVQ----RLPTD-PRRVWRNGIKAFFTAFSSHRALARAATEALATSSE 130
Query 131 IRDILERQFQVLLRETIGVFEAEVKAGTAHPI--SEDLPTLVRTLAATTAL-MLTGDALL 187
+R + Q + +T + AE + G A + DL T + + T + L+ +
Sbjct 131 LRSVWSGFMQKWIDQTAAMITAERERGAAPDTIPAADLATSLNQMNERTMMAALSAETPA 190
Query 188 VGPDSDAARRVRVLEQMWLNALWG 211
V D R V L +W+++++G
Sbjct 191 VAED----RVVDTLTHIWVSSIYG 210
>gi|288918443|ref|ZP_06412795.1| transcriptional regulator, TetR family [Frankia sp. EUN1f]
gi|288350206|gb|EFC84431.1| transcriptional regulator, TetR family [Frankia sp. EUN1f]
Length=212
Score = 67.8 bits (164), Expect = 9e-10, Method: Compositional matrix adjust.
Identities = 57/189 (31%), Positives = 94/189 (50%), Gaps = 11/189 (5%)
Query 26 ILRAARELLEETPFAELSVRAISLRAGVARSGFYFYFDSKYSVLAQILAEATEELEEASQ 85
++RA ELL+E E++V AI+ AGV+RS FYFYF+ K + A + ++ +E+ A+
Sbjct 1 MMRALDELLKERDLDEINVAAITAEAGVSRSAFYFYFEDKAACAAALGSDVYQEVLTATH 60
Query 86 HFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRACNAARQSDMEIRDILERQFQVLLRE 145
G P + ++R I +V + N+ + + ARQ +R + + + +
Sbjct 61 ALIT--SGGPPRERISRTIQAVLTSWENHRHLFQGMLVARQRSETVRRLWDEYRESFIGP 118
Query 146 TIGVFEAEVKAGTAH--PISEDLPTLVRTLAATTALML-TGDALLVGPDSDAARRVRVLE 202
+ +AE AGTA P S L T++ L + L TG GP S A +R L
Sbjct 119 LAEMIDAERAAGTASAGPDSRALVTVLLELNDRSLEQLSTG-----GPLS-ADQRAEALT 172
Query 203 QMWLNALWG 211
+WL ++G
Sbjct 173 TIWLRTIYG 181
>gi|41406277|ref|NP_959113.1| hypothetical protein MAP0179c [Mycobacterium avium subsp. paratuberculosis
K-10]
gi|41394625|gb|AAS02496.1| hypothetical protein MAP_0179c [Mycobacterium avium subsp. paratuberculosis
K-10]
Length=213
Score = 67.8 bits (164), Expect = 9e-10, Method: Compositional matrix adjust.
Identities = 60/204 (30%), Positives = 97/204 (48%), Gaps = 16/204 (7%)
Query 15 MRRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYFYFDSK----YSVLA 70
+R GD QAIL A LLE PFA +SV ++ AG++R FYFYF SK S+L
Sbjct 16 IRPTGDEREQAILATAERLLETRPFAGISVDDLAKGAGLSRPTFYFYFKSKEAVVLSLLE 75
Query 71 QILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRACNAARQSDME 130
++A A E + A Q R P + P + I + ++++ + RA A + E
Sbjct 76 PVIARADAEFDGAVQ----RLPTD-PRRVWRNGIKAFFTAFSSHRALARAATEALATSSE 130
Query 131 IRDILERQFQVLLRETIGVFEAEVKAGTAHPI--SEDLPTLVRTLAATTAL-MLTGDALL 187
+R + Q + +T + AE + G A + DL T + + T + L+ +
Sbjct 131 LRAVWSGFMQKWIDQTAAMITAERERGAAPDTIPAADLATSLNQMNERTMMAALSAETPA 190
Query 188 VGPDSDAARRVRVLEQMWLNALWG 211
V D R V L +W+++++G
Sbjct 191 VAED----RVVDTLTHIWVSSIYG 210
>gi|336461862|gb|EGO40717.1| transcriptional regulator [Mycobacterium avium subsp. paratuberculosis
S397]
Length=213
Score = 67.4 bits (163), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 60/204 (30%), Positives = 97/204 (48%), Gaps = 16/204 (7%)
Query 15 MRRRGDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYFYFDSK----YSVLA 70
+R GD QAIL A LLE PFA +SV ++ AG++R FYFYF SK S+L
Sbjct 16 IRPTGDEREQAILATAGRLLETRPFAGISVDDLAKGAGLSRPTFYFYFKSKEAVVLSLLE 75
Query 71 QILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRACNAARQSDME 130
++A A E + A Q R P + P + I + ++++ + RA A + E
Sbjct 76 PVIARADAEFDGAVQ----RLPTD-PRRVWRNGIKAFFTAFSSHRALARAATEALATSSE 130
Query 131 IRDILERQFQVLLRETIGVFEAEVKAGTAHPI--SEDLPTLVRTLAATTAL-MLTGDALL 187
+R + Q + +T + AE + G A + DL T + + T + L+ +
Sbjct 131 LRAVWSGFMQKWIDQTAAMITAERERGAAPDTIPAADLATSLNQMNERTMMAALSAETPA 190
Query 188 VGPDSDAARRVRVLEQMWLNALWG 211
V D R V L +W+++++G
Sbjct 191 VAED----RVVDTLTHIWVSSIYG 210
>gi|118462781|ref|YP_884182.1| TetR family transcriptional regulator [Mycobacterium avium 104]
gi|118164068|gb|ABK64965.1| transcriptional regulator, TetR family protein, putative [Mycobacterium
avium 104]
Length=192
Score = 67.4 bits (163), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 38/101 (38%), Positives = 58/101 (58%), Gaps = 0/101 (0%)
Query 21 RHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYFYFDSKYSVLAQILAEATEEL 80
R ++ A LLE PF ++SV I AGV+R+ FYFYF SK+SVL+ +L +A ++
Sbjct 2 RAVDSLFAATLTLLESRPFTDISVADILEVAGVSRATFYFYFSSKFSVLSGLLEQAMGDI 61
Query 81 EEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRAC 121
Q F +R SP++ + R + +V A + + VLRA
Sbjct 62 FSTVQPFLSRSDDASPQEALERSLRAVTAAWHRHRAVLRAA 102
>gi|119871173|ref|YP_941125.1| TetR family transcriptional regulator [Mycobacterium sp. KMS]
gi|119697262|gb|ABL94335.1| transcriptional regulator, TetR family [Mycobacterium sp. KMS]
Length=209
Score = 66.2 bits (160), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 67/219 (31%), Positives = 97/219 (45%), Gaps = 33/219 (15%)
Query 9 KQAAPPMRRR-----GDRHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYFYFD 63
QA P RR GD QAIL A +LLE PFAE+SV ++ AG++R FYFYF
Sbjct 5 SQARAPRGRRSARPSGDDREQAILATAEQLLEARPFAEISVDDLAKGAGISRPTFYFYFG 64
Query 64 SKYSVL----AQILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLR 119
SK +VL +++ EA LE A+ + ++ + G+ V
Sbjct 65 SKEAVLLTLWERVIREADAALENAASNATSEDVWRPGIKVFFDTFGAHRGV--------- 115
Query 120 ACNAARQSDMEIRDILERQFQVLLRETIGVFEAEVKAGTAHPI--SEDLPTLV-----RT 172
A+ + E+RD+ R Q + T EAE + G A + D+ T + RT
Sbjct 116 TVAASGSDNAEVRDVFARFMQKWIDFTAATIEAERRRGAAPQTLPARDIATALNLMNERT 175
Query 173 LAATTALMLTGDALLVGPDSDAARRVRVLEQMWLNALWG 211
L A A G + PD R + L +W A++G
Sbjct 176 LLAAFAAETPG----IPPD----RVLDSLVHVWTCAVYG 206
Lambda K H
0.319 0.131 0.370
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 260686263632
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
Posted date: Sep 5, 2011 4:36 AM
Number of letters in database: 5,219,829,388
Number of sequences in database: 15,229,318
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40