BLASTP 2.2.25+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.



Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
           15,229,318 sequences; 5,219,829,388 total letters



Query= Rv3059

Length=492
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

gi|15610196|ref|NP_217575.1|  cytochrome P450 136 [Mycobacterium ...  1021    0.0   
gi|253797842|ref|YP_003030843.1|  cytochrome P450 136 cyp136 [Myc...  1021    0.0   
gi|31794237|ref|NP_856730.1|  cytochrome P450 136 [Mycobacterium ...  1018    0.0   
gi|121638944|ref|YP_979168.1|  putative cytochrome P450 136 cyp13...  1017    0.0   
gi|306777365|ref|ZP_07415702.1|  cytochrome P450 136 cyp136 [Myco...   952    0.0   
gi|289751732|ref|ZP_06511110.1|  LOW QUALITY PROTEIN: cytochrome ...   893    0.0   
gi|240171829|ref|ZP_04750488.1|  cytochrome P450 136A2 Cyp136A2 [...   852    0.0   
gi|183981648|ref|YP_001849939.1|  cytochrome P450 136A2 Cyp136A2 ...   846    0.0   
gi|118618717|ref|YP_907049.1|  cytochrome P450 136A2 Cyp136A2 [My...   840    0.0   
gi|333991434|ref|YP_004524048.1|  cytochrome P450 [Mycobacterium ...   835    0.0   
gi|254820773|ref|ZP_05225774.1|  cytochrome p450 [Mycobacterium i...   756    0.0   
gi|108798776|ref|YP_638973.1|  cytochrome P450 [Mycobacterium sp....   754    0.0   
gi|342858090|ref|ZP_08714745.1|  cytochrome P450 [Mycobacterium c...   746    0.0   
gi|118466912|ref|YP_883089.1|  cytochrome p450 [Mycobacterium avi...   744    0.0   
gi|41409207|ref|NP_962043.1|  hypothetical protein MAP3109 [Mycob...   742    0.0   
gi|336459247|gb|EGO38192.1|  cytochrome P450 [Mycobacterium avium...   741    0.0   
gi|296171145|ref|ZP_06852593.1|  P450 heme-thiolate protein [Myco...   734    0.0   
gi|145224894|ref|YP_001135572.1|  cytochrome P450 [Mycobacterium ...   703    0.0   
gi|120403025|ref|YP_952854.1|  cytochrome P450 [Mycobacterium van...   681    0.0   
gi|169630504|ref|YP_001704153.1|  cytochrome P450 [Mycobacterium ...   681    0.0   
gi|333991433|ref|YP_004524047.1|  cytochrome P450 [Mycobacterium ...   681    0.0   
gi|118468969|ref|YP_886639.1|  cytochrome p450 [Mycobacterium sme...   679    0.0   
gi|296395038|ref|YP_003659922.1|  cytochrome P450 [Segniliparus r...   609    4e-172
gi|317508965|ref|ZP_07966598.1|  cytochrome P450 [Segniliparus ru...   592    5e-167
gi|300784780|ref|YP_003765071.1|  cytochrome P450 [Amycolatopsis ...   477    2e-132
gi|302525962|ref|ZP_07278304.1|  cytochrome P450 [Streptomyces sp...   457    3e-126
gi|226349657|ref|YP_002776771.1|  cytochrome P450 [Rhodococcus op...   450    3e-124
gi|333920600|ref|YP_004494181.1|  cytochrome P450 [Amycolicicoccu...   441    1e-121
gi|229491086|ref|ZP_04384916.1|  cytochrome P450 monooxygenase [R...   431    1e-118
gi|269127924|ref|YP_003301294.1|  cytochrome P450 [Thermomonospor...   422    1e-115
gi|325001074|ref|ZP_08122186.1|  cytochrome P450 [Pseudonocardia ...   417    3e-114
gi|326385246|ref|ZP_08206910.1|  cytochrome P450 [Gordonia neofel...   413    4e-113
gi|226364670|ref|YP_002782452.1|  cytochrome P450 [Rhodococcus op...   410    2e-112
gi|294811192|ref|ZP_06769835.1|  Cytochrome P450 [Streptomyces cl...   405    1e-110
gi|262202429|ref|YP_003273637.1|  cytochrome P450 [Gordonia bronc...   400    3e-109
gi|111022177|ref|YP_705149.1|  cytochrome P450 [Rhodococcus josti...   400    3e-109
gi|183983133|ref|YP_001851424.1|  cytochrome P450 136B2 Cyp136B2 ...   399    5e-109
gi|343927897|ref|ZP_08767363.1|  putative cytochrome P450 [Gordon...   399    5e-109
gi|108800154|ref|YP_640351.1|  cytochrome P450 [Mycobacterium sp....   397    3e-108
gi|296165242|ref|ZP_06847789.1|  P450 heme-thiolate protein [Myco...   395    7e-108
gi|23573434|gb|AAN38721.1|  cytochrome p450 [Mycobacterium absces...   394    2e-107
gi|169629164|ref|YP_001702813.1|  cytochrome P450 [Mycobacterium ...   394    2e-107
gi|326330071|ref|ZP_08196385.1|  P450 heme-thiolate protein [Noca...   386    4e-105
gi|321176309|gb|ADW77638.1|  cytochrome P450 [Rhodococcus sp. R04]     386    6e-105
gi|229493038|ref|ZP_04386833.1|  cytochrome P450 [Rhodococcus ery...   385    7e-105
gi|226308490|ref|YP_002768450.1|  cytochrome P450 [Rhodococcus er...   382    6e-104
gi|311742069|ref|ZP_07715879.1|  P450 heme-thiolate protein [Aero...   378    1e-102
gi|325673495|ref|ZP_08153186.1|  P450 heme-thiolate protein [Rhod...   378    1e-102
gi|108801810|ref|YP_642007.1|  cytochrome P450 [Mycobacterium sp....   374    3e-101
gi|126437779|ref|YP_001073470.1|  cytochrome P450 [Mycobacterium ...   373    4e-101


>gi|15610196|ref|NP_217575.1| cytochrome P450 136 [Mycobacterium tuberculosis H37Rv]
 gi|15842626|ref|NP_337663.1| P450 heme-thiolate protein [Mycobacterium tuberculosis CDC1551]
 gi|148662912|ref|YP_001284435.1| putative cytochrome p450 136 CYP136 [Mycobacterium tuberculosis 
H37Ra]
 38 more sequence titles
 Length=492

 Score = 1021 bits (2640),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 492/492 (100%), Positives = 492/492 (100%), Gaps = 0/492 (0%)

Query  1    MATIHPPAYLLDQAKRRFTPSFNNFPGMSLVEHMLLNTKFPEKKLAEPPPGSGLKPVVGD  60
            MATIHPPAYLLDQAKRRFTPSFNNFPGMSLVEHMLLNTKFPEKKLAEPPPGSGLKPVVGD
Sbjct  1    MATIHPPAYLLDQAKRRFTPSFNNFPGMSLVEHMLLNTKFPEKKLAEPPPGSGLKPVVGD  60

Query  61   AGLPILGHMIEMLRGGPDYLMFLYKTKGPVVFGDSAVLPGVAALGPDAAQVIYSNRNKDY  120
            AGLPILGHMIEMLRGGPDYLMFLYKTKGPVVFGDSAVLPGVAALGPDAAQVIYSNRNKDY
Sbjct  61   AGLPILGHMIEMLRGGPDYLMFLYKTKGPVVFGDSAVLPGVAALGPDAAQVIYSNRNKDY  120

Query  121  SQQGWVPVIGPFFHRGLMLLDFEEHMFHRRIMQEAFVRSRLAGYLEQMDRVVSRVVADDW  180
            SQQGWVPVIGPFFHRGLMLLDFEEHMFHRRIMQEAFVRSRLAGYLEQMDRVVSRVVADDW
Sbjct  121  SQQGWVPVIGPFFHRGLMLLDFEEHMFHRRIMQEAFVRSRLAGYLEQMDRVVSRVVADDW  180

Query  181  VVNDARFLVYPAMKALTLDIASMVFMGHEPGTDHELVTKVNKAFTITTRAGNAVIRTSVP  240
            VVNDARFLVYPAMKALTLDIASMVFMGHEPGTDHELVTKVNKAFTITTRAGNAVIRTSVP
Sbjct  181  VVNDARFLVYPAMKALTLDIASMVFMGHEPGTDHELVTKVNKAFTITTRAGNAVIRTSVP  240

Query  241  PFTWWRGLRARELLENYFTARVKERREASGNDLLTVLCQTEDDDGNRFSDADIVNHMIFL  300
            PFTWWRGLRARELLENYFTARVKERREASGNDLLTVLCQTEDDDGNRFSDADIVNHMIFL
Sbjct  241  PFTWWRGLRARELLENYFTARVKERREASGNDLLTVLCQTEDDDGNRFSDADIVNHMIFL  300

Query  301  MMAAHDTSTSTATTMAYQLAAHPEWQQRCRDESDRHGDGPLDIESLEQLESLDLVMNESI  360
            MMAAHDTSTSTATTMAYQLAAHPEWQQRCRDESDRHGDGPLDIESLEQLESLDLVMNESI
Sbjct  301  MMAAHDTSTSTATTMAYQLAAHPEWQQRCRDESDRHGDGPLDIESLEQLESLDLVMNESI  360

Query  361  RLVTPVQWAMRQTVRDTELLGYYLPKGTNVIAYPGMNHRLPEIWTDPLTFDPERFTEPRN  420
            RLVTPVQWAMRQTVRDTELLGYYLPKGTNVIAYPGMNHRLPEIWTDPLTFDPERFTEPRN
Sbjct  361  RLVTPVQWAMRQTVRDTELLGYYLPKGTNVIAYPGMNHRLPEIWTDPLTFDPERFTEPRN  420

Query  421  EHKRHRYAFTPFGGGVHKCIGMVFDQLEIKTILHRLLRRYRLELSRPDYQPRWDYSAMPI  480
            EHKRHRYAFTPFGGGVHKCIGMVFDQLEIKTILHRLLRRYRLELSRPDYQPRWDYSAMPI
Sbjct  421  EHKRHRYAFTPFGGGVHKCIGMVFDQLEIKTILHRLLRRYRLELSRPDYQPRWDYSAMPI  480

Query  481  PMDGMPIVLRPR  492
            PMDGMPIVLRPR
Sbjct  481  PMDGMPIVLRPR  492


>gi|253797842|ref|YP_003030843.1| cytochrome P450 136 cyp136 [Mycobacterium tuberculosis KZN 1435]
 gi|289553150|ref|ZP_06442360.1| cytochrome P450 136 cyp136 [Mycobacterium tuberculosis KZN 605]
 gi|297635690|ref|ZP_06953470.1| cytochrome P450 [Mycobacterium tuberculosis KZN 4207]
 gi|297732688|ref|ZP_06961806.1| cytochrome P450 [Mycobacterium tuberculosis KZN R506]
 gi|313660020|ref|ZP_07816900.1| cytochrome P450 [Mycobacterium tuberculosis KZN V2475]
 gi|253319345|gb|ACT23948.1| cytochrome P450 136 cyp136 [Mycobacterium tuberculosis KZN 1435]
 gi|289437782|gb|EFD20275.1| cytochrome P450 136 cyp136 [Mycobacterium tuberculosis KZN 605]
 gi|328457620|gb|AEB03043.1| cytochrome P450 136 cyp136 [Mycobacterium tuberculosis KZN 4207]
Length=492

 Score = 1021 bits (2639),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 491/492 (99%), Positives = 492/492 (100%), Gaps = 0/492 (0%)

Query  1    MATIHPPAYLLDQAKRRFTPSFNNFPGMSLVEHMLLNTKFPEKKLAEPPPGSGLKPVVGD  60
            MATIHPPAYLLDQAKRRFTPSFNNFPGMSLVEHMLLNTKFPEKKLAEPPPGSGLKPVVGD
Sbjct  1    MATIHPPAYLLDQAKRRFTPSFNNFPGMSLVEHMLLNTKFPEKKLAEPPPGSGLKPVVGD  60

Query  61   AGLPILGHMIEMLRGGPDYLMFLYKTKGPVVFGDSAVLPGVAALGPDAAQVIYSNRNKDY  120
            AGLPILGHMIEMLRGGPDYLMFLYKTKGPVVFGDSAVLPGVAALGPDAAQVIYSNRNKDY
Sbjct  61   AGLPILGHMIEMLRGGPDYLMFLYKTKGPVVFGDSAVLPGVAALGPDAAQVIYSNRNKDY  120

Query  121  SQQGWVPVIGPFFHRGLMLLDFEEHMFHRRIMQEAFVRSRLAGYLEQMDRVVSRVVADDW  180
            SQQGWVPVIGPFFHRGLMLLDFEEHMFHRRIMQEAFVRSRLAGYLEQMDRVVSRVVADDW
Sbjct  121  SQQGWVPVIGPFFHRGLMLLDFEEHMFHRRIMQEAFVRSRLAGYLEQMDRVVSRVVADDW  180

Query  181  VVNDARFLVYPAMKALTLDIASMVFMGHEPGTDHELVTKVNKAFTITTRAGNAVIRTSVP  240
            VVNDARFL+YPAMKALTLDIASMVFMGHEPGTDHELVTKVNKAFTITTRAGNAVIRTSVP
Sbjct  181  VVNDARFLIYPAMKALTLDIASMVFMGHEPGTDHELVTKVNKAFTITTRAGNAVIRTSVP  240

Query  241  PFTWWRGLRARELLENYFTARVKERREASGNDLLTVLCQTEDDDGNRFSDADIVNHMIFL  300
            PFTWWRGLRARELLENYFTARVKERREASGNDLLTVLCQTEDDDGNRFSDADIVNHMIFL
Sbjct  241  PFTWWRGLRARELLENYFTARVKERREASGNDLLTVLCQTEDDDGNRFSDADIVNHMIFL  300

Query  301  MMAAHDTSTSTATTMAYQLAAHPEWQQRCRDESDRHGDGPLDIESLEQLESLDLVMNESI  360
            MMAAHDTSTSTATTMAYQLAAHPEWQQRCRDESDRHGDGPLDIESLEQLESLDLVMNESI
Sbjct  301  MMAAHDTSTSTATTMAYQLAAHPEWQQRCRDESDRHGDGPLDIESLEQLESLDLVMNESI  360

Query  361  RLVTPVQWAMRQTVRDTELLGYYLPKGTNVIAYPGMNHRLPEIWTDPLTFDPERFTEPRN  420
            RLVTPVQWAMRQTVRDTELLGYYLPKGTNVIAYPGMNHRLPEIWTDPLTFDPERFTEPRN
Sbjct  361  RLVTPVQWAMRQTVRDTELLGYYLPKGTNVIAYPGMNHRLPEIWTDPLTFDPERFTEPRN  420

Query  421  EHKRHRYAFTPFGGGVHKCIGMVFDQLEIKTILHRLLRRYRLELSRPDYQPRWDYSAMPI  480
            EHKRHRYAFTPFGGGVHKCIGMVFDQLEIKTILHRLLRRYRLELSRPDYQPRWDYSAMPI
Sbjct  421  EHKRHRYAFTPFGGGVHKCIGMVFDQLEIKTILHRLLRRYRLELSRPDYQPRWDYSAMPI  480

Query  481  PMDGMPIVLRPR  492
            PMDGMPIVLRPR
Sbjct  481  PMDGMPIVLRPR  492


>gi|31794237|ref|NP_856730.1| cytochrome P450 136 [Mycobacterium bovis AF2122/97]
 gi|289444622|ref|ZP_06434366.1| cytochrome P450 136 cyp136 [Mycobacterium tuberculosis T46]
 gi|289448738|ref|ZP_06438482.1| cytochrome P450 136 cyp136 [Mycobacterium tuberculosis CPHL_A]
 23 more sequence titles
 Length=492

 Score = 1018 bits (2633),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 491/492 (99%), Positives = 491/492 (99%), Gaps = 0/492 (0%)

Query  1    MATIHPPAYLLDQAKRRFTPSFNNFPGMSLVEHMLLNTKFPEKKLAEPPPGSGLKPVVGD  60
            MATIHPPAYLLDQAKRRFTPSFNNFPGMSLVEHMLLNTKFPEKKLAEPPPGSGLKPVVGD
Sbjct  1    MATIHPPAYLLDQAKRRFTPSFNNFPGMSLVEHMLLNTKFPEKKLAEPPPGSGLKPVVGD  60

Query  61   AGLPILGHMIEMLRGGPDYLMFLYKTKGPVVFGDSAVLPGVAALGPDAAQVIYSNRNKDY  120
            AGLPILGHMIEMLRGGPDYLMFLYKTKGPVVFGDSAVLPGVAALGPDAAQVIYSNRNKDY
Sbjct  61   AGLPILGHMIEMLRGGPDYLMFLYKTKGPVVFGDSAVLPGVAALGPDAAQVIYSNRNKDY  120

Query  121  SQQGWVPVIGPFFHRGLMLLDFEEHMFHRRIMQEAFVRSRLAGYLEQMDRVVSRVVADDW  180
            SQQGWVPVIGPFFHRGLMLLDFEEHMFHRRIMQEAFVRSRLAGYLEQMDRVVSRVVADDW
Sbjct  121  SQQGWVPVIGPFFHRGLMLLDFEEHMFHRRIMQEAFVRSRLAGYLEQMDRVVSRVVADDW  180

Query  181  VVNDARFLVYPAMKALTLDIASMVFMGHEPGTDHELVTKVNKAFTITTRAGNAVIRTSVP  240
            VVNDARFLVYPAMKALTLDIASMVFMGHEPGTDHELVTKVNKAFTITTRAGNAVIRTSVP
Sbjct  181  VVNDARFLVYPAMKALTLDIASMVFMGHEPGTDHELVTKVNKAFTITTRAGNAVIRTSVP  240

Query  241  PFTWWRGLRARELLENYFTARVKERREASGNDLLTVLCQTEDDDGNRFSDADIVNHMIFL  300
            PFTWWRGLRARELLENYFTARVKERREASGNDLLTVLCQTEDDDGNRFSDADIVNHMIFL
Sbjct  241  PFTWWRGLRARELLENYFTARVKERREASGNDLLTVLCQTEDDDGNRFSDADIVNHMIFL  300

Query  301  MMAAHDTSTSTATTMAYQLAAHPEWQQRCRDESDRHGDGPLDIESLEQLESLDLVMNESI  360
            MMAAHDTSTSTATTMAYQLAAHPEWQQRCRDESDRHGDGPLDIESLEQLESLDLVMNESI
Sbjct  301  MMAAHDTSTSTATTMAYQLAAHPEWQQRCRDESDRHGDGPLDIESLEQLESLDLVMNESI  360

Query  361  RLVTPVQWAMRQTVRDTELLGYYLPKGTNVIAYPGMNHRLPEIWTDPLTFDPERFTEPRN  420
            RLVTPVQWAMRQTVRDTELLGYYLPKGTNVIAYPGMNHRLPEIWTDPLTFDPERFTEPRN
Sbjct  361  RLVTPVQWAMRQTVRDTELLGYYLPKGTNVIAYPGMNHRLPEIWTDPLTFDPERFTEPRN  420

Query  421  EHKRHRYAFTPFGGGVHKCIGMVFDQLEIKTILHRLLRRYRLELSRPDYQPRWDYSAMPI  480
            EHKRHRYAFTPFGGGVHKCIGMVF QLEIKTILHRLLRRYRLELSRPDYQPRWDYSAMPI
Sbjct  421  EHKRHRYAFTPFGGGVHKCIGMVFGQLEIKTILHRLLRRYRLELSRPDYQPRWDYSAMPI  480

Query  481  PMDGMPIVLRPR  492
            PMDGMPIVLRPR
Sbjct  481  PMDGMPIVLRPR  492


>gi|121638944|ref|YP_979168.1| putative cytochrome P450 136 cyp136 [Mycobacterium bovis BCG 
str. Pasteur 1173P2]
 gi|224991436|ref|YP_002646125.1| putative cytochrome P450 136 [Mycobacterium bovis BCG str. Tokyo 
172]
 gi|121494592|emb|CAL73073.1| Probable cytochrome P450 136 cyp136 [Mycobacterium bovis BCG 
str. Pasteur 1173P2]
 gi|224774551|dbj|BAH27357.1| putative cytochrome P450 136 [Mycobacterium bovis BCG str. Tokyo 
172]
 gi|341602983|emb|CCC65661.1| probable cytochrome P450 136 cyp136 [Mycobacterium bovis BCG 
str. Moreau RDJ]
Length=492

 Score = 1017 bits (2629),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 490/492 (99%), Positives = 491/492 (99%), Gaps = 0/492 (0%)

Query  1    MATIHPPAYLLDQAKRRFTPSFNNFPGMSLVEHMLLNTKFPEKKLAEPPPGSGLKPVVGD  60
            MATIHPPAYLLDQAKRRFTPSFNNFPGMSLVEHMLLNTKFPEK+LAEPPPGSGLKPVVGD
Sbjct  1    MATIHPPAYLLDQAKRRFTPSFNNFPGMSLVEHMLLNTKFPEKELAEPPPGSGLKPVVGD  60

Query  61   AGLPILGHMIEMLRGGPDYLMFLYKTKGPVVFGDSAVLPGVAALGPDAAQVIYSNRNKDY  120
            AGLPILGHMIEMLRGGPDYLMFLYKTKGPVVFGDSAVLPGVAALGPDAAQVIYSNRNKDY
Sbjct  61   AGLPILGHMIEMLRGGPDYLMFLYKTKGPVVFGDSAVLPGVAALGPDAAQVIYSNRNKDY  120

Query  121  SQQGWVPVIGPFFHRGLMLLDFEEHMFHRRIMQEAFVRSRLAGYLEQMDRVVSRVVADDW  180
            SQQGWVPVIGPFFHRGLMLLDFEEHMFHRRIMQEAFVRSRLAGYLEQMDRVVSRVVADDW
Sbjct  121  SQQGWVPVIGPFFHRGLMLLDFEEHMFHRRIMQEAFVRSRLAGYLEQMDRVVSRVVADDW  180

Query  181  VVNDARFLVYPAMKALTLDIASMVFMGHEPGTDHELVTKVNKAFTITTRAGNAVIRTSVP  240
            VVNDARFLVYPAMKALTLDIASMVFMGHEPGTDHELVTKVNKAFTITTRAGNAVIRTSVP
Sbjct  181  VVNDARFLVYPAMKALTLDIASMVFMGHEPGTDHELVTKVNKAFTITTRAGNAVIRTSVP  240

Query  241  PFTWWRGLRARELLENYFTARVKERREASGNDLLTVLCQTEDDDGNRFSDADIVNHMIFL  300
            PFTWWRGLRARELLENYFTARVKERREASGNDLLTVLCQTEDDDGNRFSDADIVNHMIFL
Sbjct  241  PFTWWRGLRARELLENYFTARVKERREASGNDLLTVLCQTEDDDGNRFSDADIVNHMIFL  300

Query  301  MMAAHDTSTSTATTMAYQLAAHPEWQQRCRDESDRHGDGPLDIESLEQLESLDLVMNESI  360
            MMAAHDTSTSTATTMAYQLAAHPEWQQRCRDESDRHGDGPLDIESLEQLESLDLVMNESI
Sbjct  301  MMAAHDTSTSTATTMAYQLAAHPEWQQRCRDESDRHGDGPLDIESLEQLESLDLVMNESI  360

Query  361  RLVTPVQWAMRQTVRDTELLGYYLPKGTNVIAYPGMNHRLPEIWTDPLTFDPERFTEPRN  420
            RLVTPVQWAMRQTVRDTELLGYYLPKGTNVIAYPGMNHRLPEIWTDPLTFDPERFTEPRN
Sbjct  361  RLVTPVQWAMRQTVRDTELLGYYLPKGTNVIAYPGMNHRLPEIWTDPLTFDPERFTEPRN  420

Query  421  EHKRHRYAFTPFGGGVHKCIGMVFDQLEIKTILHRLLRRYRLELSRPDYQPRWDYSAMPI  480
            EHKRHRYAFTPFGGGVHKCIGMVF QLEIKTILHRLLRRYRLELSRPDYQPRWDYSAMPI
Sbjct  421  EHKRHRYAFTPFGGGVHKCIGMVFGQLEIKTILHRLLRRYRLELSRPDYQPRWDYSAMPI  480

Query  481  PMDGMPIVLRPR  492
            PMDGMPIVLRPR
Sbjct  481  PMDGMPIVLRPR  492


>gi|306777365|ref|ZP_07415702.1| cytochrome P450 136 cyp136 [Mycobacterium tuberculosis SUMu001]
 gi|308214257|gb|EFO73656.1| cytochrome P450 136 cyp136 [Mycobacterium tuberculosis SUMu001]
Length=459

 Score =  952 bits (2461),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 459/459 (100%), Positives = 459/459 (100%), Gaps = 0/459 (0%)

Query  34   MLLNTKFPEKKLAEPPPGSGLKPVVGDAGLPILGHMIEMLRGGPDYLMFLYKTKGPVVFG  93
            MLLNTKFPEKKLAEPPPGSGLKPVVGDAGLPILGHMIEMLRGGPDYLMFLYKTKGPVVFG
Sbjct  1    MLLNTKFPEKKLAEPPPGSGLKPVVGDAGLPILGHMIEMLRGGPDYLMFLYKTKGPVVFG  60

Query  94   DSAVLPGVAALGPDAAQVIYSNRNKDYSQQGWVPVIGPFFHRGLMLLDFEEHMFHRRIMQ  153
            DSAVLPGVAALGPDAAQVIYSNRNKDYSQQGWVPVIGPFFHRGLMLLDFEEHMFHRRIMQ
Sbjct  61   DSAVLPGVAALGPDAAQVIYSNRNKDYSQQGWVPVIGPFFHRGLMLLDFEEHMFHRRIMQ  120

Query  154  EAFVRSRLAGYLEQMDRVVSRVVADDWVVNDARFLVYPAMKALTLDIASMVFMGHEPGTD  213
            EAFVRSRLAGYLEQMDRVVSRVVADDWVVNDARFLVYPAMKALTLDIASMVFMGHEPGTD
Sbjct  121  EAFVRSRLAGYLEQMDRVVSRVVADDWVVNDARFLVYPAMKALTLDIASMVFMGHEPGTD  180

Query  214  HELVTKVNKAFTITTRAGNAVIRTSVPPFTWWRGLRARELLENYFTARVKERREASGNDL  273
            HELVTKVNKAFTITTRAGNAVIRTSVPPFTWWRGLRARELLENYFTARVKERREASGNDL
Sbjct  181  HELVTKVNKAFTITTRAGNAVIRTSVPPFTWWRGLRARELLENYFTARVKERREASGNDL  240

Query  274  LTVLCQTEDDDGNRFSDADIVNHMIFLMMAAHDTSTSTATTMAYQLAAHPEWQQRCRDES  333
            LTVLCQTEDDDGNRFSDADIVNHMIFLMMAAHDTSTSTATTMAYQLAAHPEWQQRCRDES
Sbjct  241  LTVLCQTEDDDGNRFSDADIVNHMIFLMMAAHDTSTSTATTMAYQLAAHPEWQQRCRDES  300

Query  334  DRHGDGPLDIESLEQLESLDLVMNESIRLVTPVQWAMRQTVRDTELLGYYLPKGTNVIAY  393
            DRHGDGPLDIESLEQLESLDLVMNESIRLVTPVQWAMRQTVRDTELLGYYLPKGTNVIAY
Sbjct  301  DRHGDGPLDIESLEQLESLDLVMNESIRLVTPVQWAMRQTVRDTELLGYYLPKGTNVIAY  360

Query  394  PGMNHRLPEIWTDPLTFDPERFTEPRNEHKRHRYAFTPFGGGVHKCIGMVFDQLEIKTIL  453
            PGMNHRLPEIWTDPLTFDPERFTEPRNEHKRHRYAFTPFGGGVHKCIGMVFDQLEIKTIL
Sbjct  361  PGMNHRLPEIWTDPLTFDPERFTEPRNEHKRHRYAFTPFGGGVHKCIGMVFDQLEIKTIL  420

Query  454  HRLLRRYRLELSRPDYQPRWDYSAMPIPMDGMPIVLRPR  492
            HRLLRRYRLELSRPDYQPRWDYSAMPIPMDGMPIVLRPR
Sbjct  421  HRLLRRYRLELSRPDYQPRWDYSAMPIPMDGMPIVLRPR  459


>gi|289751732|ref|ZP_06511110.1| LOW QUALITY PROTEIN: cytochrome P450 136 cyp136 [Mycobacterium 
tuberculosis T92]
 gi|289692319|gb|EFD59748.1| LOW QUALITY PROTEIN: cytochrome P450 136 cyp136 [Mycobacterium 
tuberculosis T92]
Length=493

 Score =  893 bits (2308),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 431/431 (100%), Positives = 431/431 (100%), Gaps = 0/431 (0%)

Query  1    MATIHPPAYLLDQAKRRFTPSFNNFPGMSLVEHMLLNTKFPEKKLAEPPPGSGLKPVVGD  60
            MATIHPPAYLLDQAKRRFTPSFNNFPGMSLVEHMLLNTKFPEKKLAEPPPGSGLKPVVGD
Sbjct  1    MATIHPPAYLLDQAKRRFTPSFNNFPGMSLVEHMLLNTKFPEKKLAEPPPGSGLKPVVGD  60

Query  61   AGLPILGHMIEMLRGGPDYLMFLYKTKGPVVFGDSAVLPGVAALGPDAAQVIYSNRNKDY  120
            AGLPILGHMIEMLRGGPDYLMFLYKTKGPVVFGDSAVLPGVAALGPDAAQVIYSNRNKDY
Sbjct  61   AGLPILGHMIEMLRGGPDYLMFLYKTKGPVVFGDSAVLPGVAALGPDAAQVIYSNRNKDY  120

Query  121  SQQGWVPVIGPFFHRGLMLLDFEEHMFHRRIMQEAFVRSRLAGYLEQMDRVVSRVVADDW  180
            SQQGWVPVIGPFFHRGLMLLDFEEHMFHRRIMQEAFVRSRLAGYLEQMDRVVSRVVADDW
Sbjct  121  SQQGWVPVIGPFFHRGLMLLDFEEHMFHRRIMQEAFVRSRLAGYLEQMDRVVSRVVADDW  180

Query  181  VVNDARFLVYPAMKALTLDIASMVFMGHEPGTDHELVTKVNKAFTITTRAGNAVIRTSVP  240
            VVNDARFLVYPAMKALTLDIASMVFMGHEPGTDHELVTKVNKAFTITTRAGNAVIRTSVP
Sbjct  181  VVNDARFLVYPAMKALTLDIASMVFMGHEPGTDHELVTKVNKAFTITTRAGNAVIRTSVP  240

Query  241  PFTWWRGLRARELLENYFTARVKERREASGNDLLTVLCQTEDDDGNRFSDADIVNHMIFL  300
            PFTWWRGLRARELLENYFTARVKERREASGNDLLTVLCQTEDDDGNRFSDADIVNHMIFL
Sbjct  241  PFTWWRGLRARELLENYFTARVKERREASGNDLLTVLCQTEDDDGNRFSDADIVNHMIFL  300

Query  301  MMAAHDTSTSTATTMAYQLAAHPEWQQRCRDESDRHGDGPLDIESLEQLESLDLVMNESI  360
            MMAAHDTSTSTATTMAYQLAAHPEWQQRCRDESDRHGDGPLDIESLEQLESLDLVMNESI
Sbjct  301  MMAAHDTSTSTATTMAYQLAAHPEWQQRCRDESDRHGDGPLDIESLEQLESLDLVMNESI  360

Query  361  RLVTPVQWAMRQTVRDTELLGYYLPKGTNVIAYPGMNHRLPEIWTDPLTFDPERFTEPRN  420
            RLVTPVQWAMRQTVRDTELLGYYLPKGTNVIAYPGMNHRLPEIWTDPLTFDPERFTEPRN
Sbjct  361  RLVTPVQWAMRQTVRDTELLGYYLPKGTNVIAYPGMNHRLPEIWTDPLTFDPERFTEPRN  420

Query  421  EHKRHRYAFTP  431
            EHKRHRYAFTP
Sbjct  421  EHKRHRYAFTP  431


>gi|240171829|ref|ZP_04750488.1| cytochrome P450 136A2 Cyp136A2 [Mycobacterium kansasii ATCC 12478]
Length=496

 Score =  852 bits (2202),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 427/490 (88%), Positives = 455/490 (93%), Gaps = 0/490 (0%)

Query  2    ATIHPPAYLLDQAKRRFTPSFNNFPGMSLVEHMLLNTKFPEKKLAEPPPGSGLKPVVGDA  61
            ATI  PAYLLDQA+RR TPSFNNFPGM LVE  LLNT+FPEK+LA+PPPGSGLKPVVGDA
Sbjct  6    ATISTPAYLLDQAQRRLTPSFNNFPGMGLVERWLLNTQFPEKRLADPPPGSGLKPVVGDA  65

Query  62   GLPILGHMIEMLRGGPDYLMFLYKTKGPVVFGDSAVLPGVAALGPDAAQVIYSNRNKDYS  121
            GLPI+GHMIEMLRGGPDYLMFLY TKGPV++GDS VLP VAALGPDAAQVIYSNRNKDYS
Sbjct  66   GLPIIGHMIEMLRGGPDYLMFLYNTKGPVIYGDSPVLPFVAALGPDAAQVIYSNRNKDYS  125

Query  122  QQGWVPVIGPFFHRGLMLLDFEEHMFHRRIMQEAFVRSRLAGYLEQMDRVVSRVVADDWV  181
            QQGWVPVIGPFF RGLMLLDFEEHMFHRRIMQEAFVRSRL GY+E MD VVS+V+A+DWV
Sbjct  126  QQGWVPVIGPFFRRGLMLLDFEEHMFHRRIMQEAFVRSRLVGYVEHMDHVVSKVIAEDWV  185

Query  182  VNDARFLVYPAMKALTLDIASMVFMGHEPGTDHELVTKVNKAFTITTRAGNAVIRTSVPP  241
            +NDARFL+YPAMK LTL+IASMVFMGHEPGTD ELVT+VNKAFT TTRAGNA+IRTSVPP
Sbjct  186  INDARFLLYPAMKELTLNIASMVFMGHEPGTDRELVTQVNKAFTTTTRAGNAIIRTSVPP  245

Query  242  FTWWRGLRARELLENYFTARVKERREASGNDLLTVLCQTEDDDGNRFSDADIVNHMIFLM  301
            FTWWRGL+AR+LLE+YF  RV+ERR   GNDLLTVLCQTED+DGNRFSD DIVNHMIFLM
Sbjct  246  FTWWRGLKARQLLEHYFAERVQERRGKEGNDLLTVLCQTEDEDGNRFSDQDIVNHMIFLM  305

Query  302  MAAHDTSTSTATTMAYQLAAHPEWQQRCRDESDRHGDGPLDIESLEQLESLDLVMNESIR  361
            MAAHDTSTSTATTMAY LAAHPEWQQRCRDESDR GDGPLDIESLE+LESLDLVMNESIR
Sbjct  306  MAAHDTSTSTATTMAYHLAAHPEWQQRCRDESDRLGDGPLDIESLEKLESLDLVMNESIR  365

Query  362  LVTPVQWAMRQTVRDTELLGYYLPKGTNVIAYPGMNHRLPEIWTDPLTFDPERFTEPRNE  421
            LVTPVQWAMRQTVRD ELLGYYLPKGTNVIA+PG+NHRLPE WT+P+TFDPERFTEPRNE
Sbjct  366  LVTPVQWAMRQTVRDAELLGYYLPKGTNVIAFPGLNHRLPEFWTEPMTFDPERFTEPRNE  425

Query  422  HKRHRYAFTPFGGGVHKCIGMVFDQLEIKTILHRLLRRYRLELSRPDYQPRWDYSAMPIP  481
            HKRHRYAFTPFGGG HKC+GMVF QLEIKTILHRLLRRYRLEL RPDY   WDY  MP+P
Sbjct  426  HKRHRYAFTPFGGGAHKCLGMVFGQLEIKTILHRLLRRYRLELPRPDYHASWDYGGMPVP  485

Query  482  MDGMPIVLRP  491
             DGMPIVLRP
Sbjct  486  KDGMPIVLRP  495


>gi|183981648|ref|YP_001849939.1| cytochrome P450 136A2 Cyp136A2 [Mycobacterium marinum M]
 gi|183174974|gb|ACC40084.1| cytochrome P450 136A2 Cyp136A2 [Mycobacterium marinum M]
Length=492

 Score =  846 bits (2185),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 426/491 (87%), Positives = 448/491 (92%), Gaps = 0/491 (0%)

Query  1    MATIHPPAYLLDQAKRRFTPSFNNFPGMSLVEHMLLNTKFPEKKLAEPPPGSGLKPVVGD  60
            MATI  PAYLLDQA+RR TPSFNNFPGM +VE  LL T+FPE  LA+PPPGS LKPVVGD
Sbjct  1    MATISTPAYLLDQAQRRLTPSFNNFPGMGMVERWLLKTQFPETTLADPPPGSDLKPVVGD  60

Query  61   AGLPILGHMIEMLRGGPDYLMFLYKTKGPVVFGDSAVLPGVAALGPDAAQVIYSNRNKDY  120
            AGLPILGH+IEMLRGGPDYLMFLY+TKGPVVFGDS VLP V ALGPDAAQVIYSNRNKDY
Sbjct  61   AGLPILGHLIEMLRGGPDYLMFLYRTKGPVVFGDSPVLPAVVALGPDAAQVIYSNRNKDY  120

Query  121  SQQGWVPVIGPFFHRGLMLLDFEEHMFHRRIMQEAFVRSRLAGYLEQMDRVVSRVVADDW  180
            SQQGWVPVIGPFF RGLMLLDFEEHMFHRRIMQEAFVRSRL GY+E MD V SR +A +W
Sbjct  121  SQQGWVPVIGPFFRRGLMLLDFEEHMFHRRIMQEAFVRSRLVGYVEHMDEVASRAIAGEW  180

Query  181  VVNDARFLVYPAMKALTLDIASMVFMGHEPGTDHELVTKVNKAFTITTRAGNAVIRTSVP  240
              NDARFL+YPAMK LTLDIASMVFMGHEPGTDHELVTKVN+AFT TTRAGNAVIRTSVP
Sbjct  181  ATNDARFLLYPAMKKLTLDIASMVFMGHEPGTDHELVTKVNRAFTTTTRAGNAVIRTSVP  240

Query  241  PFTWWRGLRARELLENYFTARVKERREASGNDLLTVLCQTEDDDGNRFSDADIVNHMIFL  300
            PFTWWRG+RAR+LLENYF ARV ERR   GNDLLTVLC T D+DGNRFSD DIVNHMIFL
Sbjct  241  PFTWWRGIRARQLLENYFAARVTERRGQEGNDLLTVLCHTADEDGNRFSDQDIVNHMIFL  300

Query  301  MMAAHDTSTSTATTMAYQLAAHPEWQQRCRDESDRHGDGPLDIESLEQLESLDLVMNESI  360
            MMAAHDTSTSTATTMAY LAAHPEWQQRCRDESDR GDGPLDIE+LE+LESLDLVMNESI
Sbjct  301  MMAAHDTSTSTATTMAYHLAAHPEWQQRCRDESDRLGDGPLDIEALEKLESLDLVMNESI  360

Query  361  RLVTPVQWAMRQTVRDTELLGYYLPKGTNVIAYPGMNHRLPEIWTDPLTFDPERFTEPRN  420
            RLVTPVQWAMRQTVRDTELLGYYLPKGTNVIAYPGMNHRLPE WTDP+TFDP+RF EPRN
Sbjct  361  RLVTPVQWAMRQTVRDTELLGYYLPKGTNVIAYPGMNHRLPEFWTDPMTFDPDRFAEPRN  420

Query  421  EHKRHRYAFTPFGGGVHKCIGMVFDQLEIKTILHRLLRRYRLELSRPDYQPRWDYSAMPI  480
            EHKRHRYAFTPFGGG HKC+GMVF QLEIKTILHRLLRRYRLEL+RPDY+  WDY  MP+
Sbjct  421  EHKRHRYAFTPFGGGAHKCLGMVFGQLEIKTILHRLLRRYRLELARPDYRACWDYGGMPV  480

Query  481  PMDGMPIVLRP  491
            P DGMPIVLRP
Sbjct  481  PKDGMPIVLRP  491


>gi|118618717|ref|YP_907049.1| cytochrome P450 136A2 Cyp136A2 [Mycobacterium ulcerans Agy99]
 gi|118570827|gb|ABL05578.1| cytochrome P450 136A2 Cyp136A2 [Mycobacterium ulcerans Agy99]
Length=492

 Score =  840 bits (2169),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 423/491 (87%), Positives = 446/491 (91%), Gaps = 0/491 (0%)

Query  1    MATIHPPAYLLDQAKRRFTPSFNNFPGMSLVEHMLLNTKFPEKKLAEPPPGSGLKPVVGD  60
            MATI  PAYLLDQA+RR TPSFNNFPGM +VE  LL T+FPE  LA+PPPGS LKPVVGD
Sbjct  1    MATISTPAYLLDQAQRRLTPSFNNFPGMGMVERWLLKTQFPETTLADPPPGSDLKPVVGD  60

Query  61   AGLPILGHMIEMLRGGPDYLMFLYKTKGPVVFGDSAVLPGVAALGPDAAQVIYSNRNKDY  120
            AGLPILGH+IEMLRGGPDYLMFLY+TKGPVVFGDS VL  V ALGPDAAQVIYSNRNKDY
Sbjct  61   AGLPILGHLIEMLRGGPDYLMFLYRTKGPVVFGDSPVLSAVVALGPDAAQVIYSNRNKDY  120

Query  121  SQQGWVPVIGPFFHRGLMLLDFEEHMFHRRIMQEAFVRSRLAGYLEQMDRVVSRVVADDW  180
            SQQGWVPVIGPFF RGLMLLDFEEHMFHRRIMQ+AFVR RL GY+E MD V SR +A +W
Sbjct  121  SQQGWVPVIGPFFRRGLMLLDFEEHMFHRRIMQQAFVRPRLVGYVEHMDEVASRAIAGEW  180

Query  181  VVNDARFLVYPAMKALTLDIASMVFMGHEPGTDHELVTKVNKAFTITTRAGNAVIRTSVP  240
              NDARFL+YPAMK LTLDIASMVFMGHEPGTDHELVTKVN+AFT TTRAGNAVIRTSVP
Sbjct  181  ATNDARFLLYPAMKKLTLDIASMVFMGHEPGTDHELVTKVNRAFTTTTRAGNAVIRTSVP  240

Query  241  PFTWWRGLRARELLENYFTARVKERREASGNDLLTVLCQTEDDDGNRFSDADIVNHMIFL  300
            PFTWWRG+RAR+LLENYF ARV ERR   GNDLLTVLC T D+DGNRFSD DIVNHMIFL
Sbjct  241  PFTWWRGIRARQLLENYFAARVTERRGQEGNDLLTVLCHTADEDGNRFSDQDIVNHMIFL  300

Query  301  MMAAHDTSTSTATTMAYQLAAHPEWQQRCRDESDRHGDGPLDIESLEQLESLDLVMNESI  360
            MMAAHDTSTSTATTMAY LAAHPEWQQRCRDESDR GDGPLDIE+LE+LESLDLVMNESI
Sbjct  301  MMAAHDTSTSTATTMAYHLAAHPEWQQRCRDESDRLGDGPLDIEALEKLESLDLVMNESI  360

Query  361  RLVTPVQWAMRQTVRDTELLGYYLPKGTNVIAYPGMNHRLPEIWTDPLTFDPERFTEPRN  420
            RLVTPVQWAMRQTVRDTELLGYYLPKGTNVIAYPGMNHRLPE WTDP+TFDP+RF EPRN
Sbjct  361  RLVTPVQWAMRQTVRDTELLGYYLPKGTNVIAYPGMNHRLPEFWTDPMTFDPDRFAEPRN  420

Query  421  EHKRHRYAFTPFGGGVHKCIGMVFDQLEIKTILHRLLRRYRLELSRPDYQPRWDYSAMPI  480
            EHKRHRYAFTPFGGG HKC+GMVF QLEIKTILHRLLRRYRLEL+RPDY+  WDY  MP+
Sbjct  421  EHKRHRYAFTPFGGGAHKCLGMVFGQLEIKTILHRLLRRYRLELARPDYRACWDYGGMPV  480

Query  481  PMDGMPIVLRP  491
            P DGMPIVLRP
Sbjct  481  PKDGMPIVLRP  491


>gi|333991434|ref|YP_004524048.1| cytochrome P450 [Mycobacterium sp. JDM601]
 gi|333487402|gb|AEF36794.1| cytochrome P450 136A2 Cyp136A2 [Mycobacterium sp. JDM601]
Length=492

 Score =  835 bits (2157),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 407/491 (83%), Positives = 444/491 (91%), Gaps = 0/491 (0%)

Query  1    MATIHPPAYLLDQAKRRFTPSFNNFPGMSLVEHMLLNTKFPEKKLAEPPPGSGLKPVVGD  60
            M TI  P YL+DQAKRRFTPSFNNFPGM+ +E  LL  +FPEK+LAEPPPGSGLKPV+GD
Sbjct  1    MTTISTPRYLIDQAKRRFTPSFNNFPGMAALERRLLTMEFPEKQLAEPPPGSGLKPVLGD  60

Query  61   AGLPILGHMIEMLRGGPDYLMFLYKTKGPVVFGDSAVLPGVAALGPDAAQVIYSNRNKDY  120
            AGLPILGHMIEMLRGGPDYLM +Y T GP++FGDS VLP VAALGPDA QVIY+NR+KDY
Sbjct  61   AGLPILGHMIEMLRGGPDYLMRMYHTHGPMLFGDSPVLPAVAALGPDATQVIYANRDKDY  120

Query  121  SQQGWVPVIGPFFHRGLMLLDFEEHMFHRRIMQEAFVRSRLAGYLEQMDRVVSRVVADDW  180
            SQQGWVPVIGPFF RGLMLLDFEEHMFHRRIMQ+AFVR RL GY+EQ+D V S+V+A+DW
Sbjct  121  SQQGWVPVIGPFFKRGLMLLDFEEHMFHRRIMQQAFVRPRLVGYVEQIDLVASQVIANDW  180

Query  181  VVNDARFLVYPAMKALTLDIASMVFMGHEPGTDHELVTKVNKAFTITTRAGNAVIRTSVP  240
            V ND RFL+YPAMK LTLDIA++VFMGHEPGTD ELVTKVNKAFT TTRAGNAVIRTSVP
Sbjct  181  VSNDPRFLLYPAMKELTLDIAALVFMGHEPGTDRELVTKVNKAFTTTTRAGNAVIRTSVP  240

Query  241  PFTWWRGLRARELLENYFTARVKERREASGNDLLTVLCQTEDDDGNRFSDADIVNHMIFL  300
            PFTWWRGL+ARELLE+YFTARV+E R   GNDLLT LC  ED+DGNRF+DADIVNHMIFL
Sbjct  241  PFTWWRGLKARELLESYFTARVREHRGKEGNDLLTALCYAEDEDGNRFTDADIVNHMIFL  300

Query  301  MMAAHDTSTSTATTMAYQLAAHPEWQQRCRDESDRHGDGPLDIESLEQLESLDLVMNESI  360
            MMAAHDTSTSTAT+MAY LA +PEWQQRCRDESDR GDGPLDIESLE+LESLDLVM+ESI
Sbjct  301  MMAAHDTSTSTATSMAYNLAGNPEWQQRCRDESDRLGDGPLDIESLEKLESLDLVMDESI  360

Query  361  RLVTPVQWAMRQTVRDTELLGYYLPKGTNVIAYPGMNHRLPEIWTDPLTFDPERFTEPRN  420
            RLVTPVQWAMRQTVRDT+LLGYY+PKGTNVIAYPG+NHRLPE+WTDP+ FDPERFTEPRN
Sbjct  361  RLVTPVQWAMRQTVRDTDLLGYYIPKGTNVIAYPGVNHRLPELWTDPMKFDPERFTEPRN  420

Query  421  EHKRHRYAFTPFGGGVHKCIGMVFDQLEIKTILHRLLRRYRLELSRPDYQPRWDYSAMPI  480
            EHKRHRYAF PFGGG HKCIGM F +LE+K ILHRLLRRYRLEL  P Y+ RWDY  MPI
Sbjct  421  EHKRHRYAFNPFGGGAHKCIGMTFGRLEVKAILHRLLRRYRLELPHPGYRTRWDYGGMPI  480

Query  481  PMDGMPIVLRP  491
            PMDGMPIVLRP
Sbjct  481  PMDGMPIVLRP  491


>gi|254820773|ref|ZP_05225774.1| cytochrome p450 [Mycobacterium intracellulare ATCC 13950]
Length=492

 Score =  756 bits (1953),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 355/490 (73%), Positives = 418/490 (86%), Gaps = 1/490 (0%)

Query  2    ATIHPPAYLLDQAKRRFTPSFNNFPGMSLVEHMLLNTKFPEKKLAEPPPGSGLKPVVGDA  61
            ATI  P YLLDQA+RRFTP+ N  PGM  +E  LL  ++  K LAEPP GS LKPV+GDA
Sbjct  3    ATISTPHYLLDQARRRFTPTLNTIPGMGAIEKRLLAHEWDTKVLAEPPAGSDLKPVMGDA  62

Query  62   GLPILGHMIEMLRGGPDYLMFLYKTKGPVVFGDSAVLPGVAALGPDAAQVIYSNRNKDYS  121
            GLPILGH+IE+ RGGPDY ++LY+ KGP+++ DS ++P V ALGPDA Q ++SNRNKD+S
Sbjct  63   GLPILGHIIELFRGGPDYALYLYRNKGPLIYLDSPIMPAVTALGPDATQAVFSNRNKDFS  122

Query  122  QQGWVPVIGPFFHRGLMLLDFEEHMFHRRIMQEAFVRSRLAGYLEQMDRVVSRVVADDWV  181
            Q+GW PVIGPFF+RGLM+LDF+EHM+HRRIMQEAF RSRL GY+E +DRV + +VA  W 
Sbjct  123  QKGWHPVIGPFFNRGLMMLDFDEHMYHRRIMQEAFTRSRLTGYVEHIDRVATDIVAG-WP  181

Query  182  VNDARFLVYPAMKALTLDIASMVFMGHEPGTDHELVTKVNKAFTITTRAGNAVIRTSVPP  241
             NDARFL +PAMK LTLDIAS+VFMGHEPG+DH+LVTKVN+AFT TTRAG A+IR  VPP
Sbjct  182  TNDARFLFHPAMKELTLDIASLVFMGHEPGSDHDLVTKVNQAFTTTTRAGGAIIRQPVPP  241

Query  242  FTWWRGLRARELLENYFTARVKERREASGNDLLTVLCQTEDDDGNRFSDADIVNHMIFLM  301
            F WWRGLRAR+LLE+YF  RVKERR A+GND+LTVLC TEDDDGN F+D DIVNHMIFLM
Sbjct  242  FKWWRGLRARQLLEDYFNERVKERRNATGNDMLTVLCHTEDDDGNSFTDEDIVNHMIFLM  301

Query  302  MAAHDTSTSTATTMAYQLAAHPEWQQRCRDESDRHGDGPLDIESLEQLESLDLVMNESIR  361
            MAAHDTSTST TTM Y +AA+PEWQ+R R+ES R GDGPLDIESLE+LE+L+L+MNES+R
Sbjct  302  MAAHDTSTSTTTTMVYNMAANPEWQERAREESARLGDGPLDIESLEKLETLELIMNESLR  361

Query  362  LVTPVQWAMRQTVRDTELLGYYLPKGTNVIAYPGMNHRLPEIWTDPLTFDPERFTEPRNE  421
            +VTP+ + MR  VRDTELLG+Y+P GTN+  +PGMNHRLPE+WT+P  FDPERF EPR+E
Sbjct  362  MVTPLPFNMRMAVRDTELLGHYIPAGTNITIWPGMNHRLPELWTEPDKFDPERFAEPRSE  421

Query  422  HKRHRYAFTPFGGGVHKCIGMVFDQLEIKTILHRLLRRYRLELSRPDYQPRWDYSAMPIP  481
            HK HRYAF PFGGG HKCIGMVF QLE+KT++HRLLRRYR+EL+RP YQPRWDY  MPIP
Sbjct  422  HKNHRYAFAPFGGGAHKCIGMVFGQLEVKTVVHRLLRRYRIELARPGYQPRWDYGGMPIP  481

Query  482  MDGMPIVLRP  491
            MDGMPIVLRP
Sbjct  482  MDGMPIVLRP  491


>gi|108798776|ref|YP_638973.1| cytochrome P450 [Mycobacterium sp. MCS]
 gi|119867894|ref|YP_937846.1| cytochrome P450 [Mycobacterium sp. KMS]
 gi|108769195|gb|ABG07917.1| cytochrome P450 [Mycobacterium sp. MCS]
 gi|119693983|gb|ABL91056.1| cytochrome P450 [Mycobacterium sp. KMS]
Length=497

 Score =  754 bits (1948),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 352/495 (72%), Positives = 418/495 (85%), Gaps = 4/495 (0%)

Query  1    MATIHPPAYLLDQAKRRFTPSFNNFPGMSLVEH----MLLNTKFPEKKLAEPPPGSGLKP  56
            MATI  P YLLDQAKRRFTP+ N  PGM +VE      L N ++ +  LAEPP GSGLKP
Sbjct  1    MATISTPEYLLDQAKRRFTPTLNTIPGMGIVEKRLRDKLQNQEWKQFVLAEPPAGSGLKP  60

Query  57   VVGDAGLPILGHMIEMLRGGPDYLMFLYKTKGPVVFGDSAVLPGVAALGPDAAQVIYSNR  116
            V+GD+GLP+LGHMIE  RGGPDYL+ +YKT GP+ +  S  LP V ALGPDA Q ++SN+
Sbjct  61   VMGDSGLPVLGHMIETFRGGPDYLLQVYKTYGPLHYAYSPALPAVVALGPDATQAVFSNK  120

Query  117  NKDYSQQGWVPVIGPFFHRGLMLLDFEEHMFHRRIMQEAFVRSRLAGYLEQMDRVVSRVV  176
            NKD+SQ+GW PVIGPFF+RGLM+LDF+EHM+HRRIMQEAF R+RLAGY+E +DRV S+V+
Sbjct  121  NKDFSQRGWHPVIGPFFNRGLMMLDFDEHMYHRRIMQEAFTRTRLAGYVEHIDRVASQVI  180

Query  177  ADDWVVNDARFLVYPAMKALTLDIASMVFMGHEPGTDHELVTKVNKAFTITTRAGNAVIR  236
            A+DWV NDARFL YPA+K LTLDIAS+VFMGHEPGTD ELVTKVN AFT+TTRAG A+IR
Sbjct  181  ANDWVENDARFLFYPAVKELTLDIASVVFMGHEPGTDKELVTKVNDAFTMTTRAGGAIIR  240

Query  237  TSVPPFTWWRGLRARELLENYFTARVKERREASGNDLLTVLCQTEDDDGNRFSDADIVNH  296
            T +PPF WWRGL+AR++L+NYF  RVKE+R + G D+LTVLC T D+DGN FSD DIVNH
Sbjct  241  TGLPPFKWWRGLQARKVLDNYFEQRVKEKRGSEGTDMLTVLCHTADEDGNTFSDQDIVNH  300

Query  297  MIFLMMAAHDTSTSTATTMAYQLAAHPEWQQRCRDESDRHGDGPLDIESLEQLESLDLVM  356
            MIFLMMAAHDTSTST TTMAY L+ +PEWQ+RCR+ES+R GDGPLDIE+LE+LE+LDLV+
Sbjct  301  MIFLMMAAHDTSTSTLTTMAYHLSRNPEWQERCREESERLGDGPLDIEALEKLETLDLVI  360

Query  357  NESIRLVTPVQWAMRQTVRDTELLGYYLPKGTNVIAYPGMNHRLPEIWTDPLTFDPERFT  416
            NES+RLVTP+ + +RQTVRDTELLG+Y+P  T+V+ +P +NH LPE+WTDP  FDP RFT
Sbjct  361  NESLRLVTPLPFNVRQTVRDTELLGHYIPANTDVVLWPSVNHHLPELWTDPEKFDPARFT  420

Query  417  EPRNEHKRHRYAFTPFGGGVHKCIGMVFDQLEIKTILHRLLRRYRLELSRPDYQPRWDYS  476
            EPRNEHK+HRYAF PFGGG HKCIGMVF QLEIKT++HRLLRRYRLE  RP Y  + DY+
Sbjct  421  EPRNEHKQHRYAFAPFGGGAHKCIGMVFGQLEIKTVMHRLLRRYRLEPPRPGYVSKLDYA  480

Query  477  AMPIPMDGMPIVLRP  491
             MP+PMDGMPIVLRP
Sbjct  481  GMPVPMDGMPIVLRP  495


>gi|342858090|ref|ZP_08714745.1| cytochrome P450 [Mycobacterium colombiense CECT 3035]
 gi|342133794|gb|EGT86974.1| cytochrome P450 [Mycobacterium colombiense CECT 3035]
Length=492

 Score =  746 bits (1927),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 348/490 (72%), Positives = 417/490 (86%), Gaps = 1/490 (0%)

Query  2    ATIHPPAYLLDQAKRRFTPSFNNFPGMSLVEHMLLNTKFPEKKLAEPPPGSGLKPVVGDA  61
            ATI  P YLLDQA+RRFTP+    PGM  +E  LL  ++  K LAEPP GS LKPV+GDA
Sbjct  3    ATISTPHYLLDQARRRFTPTLQTIPGMGAIEKRLLAHEWQSKVLAEPPAGSDLKPVLGDA  62

Query  62   GLPILGHMIEMLRGGPDYLMFLYKTKGPVVFGDSAVLPGVAALGPDAAQVIYSNRNKDYS  121
            GLPILGH+IE+ RGGPDY + LY+  GP+++ DS ++P V ALGPDA Q ++SNRNKD+S
Sbjct  63   GLPILGHIIELFRGGPDYALHLYRNHGPLIYLDSPIMPAVTALGPDATQAVFSNRNKDFS  122

Query  122  QQGWVPVIGPFFHRGLMLLDFEEHMFHRRIMQEAFVRSRLAGYLEQMDRVVSRVVADDWV  181
            Q+GW PVIGPFF+RGLM+LDF+EHM+HRRIMQEAF RSRL GY+E +DRV + +VA+ W 
Sbjct  123  QKGWHPVIGPFFNRGLMMLDFDEHMYHRRIMQEAFTRSRLTGYVEHIDRVATEIVAN-WP  181

Query  182  VNDARFLVYPAMKALTLDIASMVFMGHEPGTDHELVTKVNKAFTITTRAGNAVIRTSVPP  241
             NDARFL +PAMK LTLDIAS+VFMGHEPG+DH+LVTKVN+AFT TTRAG A+IR  +PP
Sbjct  182  TNDARFLFHPAMKELTLDIASLVFMGHEPGSDHDLVTKVNQAFTTTTRAGGAIIRQPIPP  241

Query  242  FTWWRGLRARELLENYFTARVKERREASGNDLLTVLCQTEDDDGNRFSDADIVNHMIFLM  301
            F WWRGL+AR+LLE+YFT RVK+RR ASGND+LTVLC TEDDDGN F+D+DIVNHMIFLM
Sbjct  242  FKWWRGLKARKLLEDYFTERVKDRRNASGNDMLTVLCHTEDDDGNSFTDSDIVNHMIFLM  301

Query  302  MAAHDTSTSTATTMAYQLAAHPEWQQRCRDESDRHGDGPLDIESLEQLESLDLVMNESIR  361
            MAAHDTSTST TTM Y +AA+P+WQ+R R+ES R GDGPLDIESLE+LE+L+L+MNES+R
Sbjct  302  MAAHDTSTSTTTTMVYNMAANPQWQERAREESARLGDGPLDIESLEKLETLELIMNESLR  361

Query  362  LVTPVQWAMRQTVRDTELLGYYLPKGTNVIAYPGMNHRLPEIWTDPLTFDPERFTEPRNE  421
            +VTP+ + MR  VRDTELLG+Y+P GTN+  +PGMNHRL E+WT+P  FDP+RF EPR+E
Sbjct  362  MVTPLPFNMRMAVRDTELLGHYIPAGTNITIWPGMNHRLSELWTEPDKFDPDRFAEPRSE  421

Query  422  HKRHRYAFTPFGGGVHKCIGMVFDQLEIKTILHRLLRRYRLELSRPDYQPRWDYSAMPIP  481
            HK+HRYAF PFGGG HKCIGMVF QLE+KT++HRLLRRYR+EL+RP YQP WDY  MPIP
Sbjct  422  HKKHRYAFAPFGGGAHKCIGMVFGQLEVKTVVHRLLRRYRIELARPGYQPHWDYGGMPIP  481

Query  482  MDGMPIVLRP  491
            MDGMPIVLRP
Sbjct  482  MDGMPIVLRP  491


>gi|118466912|ref|YP_883089.1| cytochrome p450 [Mycobacterium avium 104]
 gi|254776346|ref|ZP_05217862.1| cytochrome p450 [Mycobacterium avium subsp. avium ATCC 25291]
 gi|118168199|gb|ABK69096.1| cytochrome p450 [Mycobacterium avium 104]
Length=492

 Score =  744 bits (1921),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 361/490 (74%), Positives = 421/490 (86%), Gaps = 1/490 (0%)

Query  2    ATIHPPAYLLDQAKRRFTPSFNNFPGMSLVEHMLLNTKFPEKKLAEPPPGSGLKPVVGDA  61
            ATI  P YLLDQA+RRFTP+ N  PGM  +E  LL  ++  K LAEPP GSGLKPV+GDA
Sbjct  3    ATISTPQYLLDQARRRFTPTLNTIPGMGAIEKRLLAHEWQTKVLAEPPAGSGLKPVLGDA  62

Query  62   GLPILGHMIEMLRGGPDYLMFLYKTKGPVVFGDSAVLPGVAALGPDAAQVIYSNRNKDYS  121
            GLPILGH+IE+ RGGPDY +FLY+  GP+++ DS ++P V ALGPDA Q ++SNRNKDYS
Sbjct  63   GLPILGHIIELFRGGPDYALFLYRNHGPLIYLDSPIMPAVTALGPDATQAVFSNRNKDYS  122

Query  122  QQGWVPVIGPFFHRGLMLLDFEEHMFHRRIMQEAFVRSRLAGYLEQMDRVVSRVVADDWV  181
            Q+GW PVIGPFF+RGLM+LDF+EHM+HRRIMQEAF RSRL GY+E +DRV + +VAD W 
Sbjct  123  QKGWHPVIGPFFNRGLMMLDFDEHMYHRRIMQEAFTRSRLTGYVEHIDRVATDIVAD-WP  181

Query  182  VNDARFLVYPAMKALTLDIASMVFMGHEPGTDHELVTKVNKAFTITTRAGNAVIRTSVPP  241
             NDARFL +PAMK LTLDIAS+VFMGHEPGTDH+LVTKVN+AFT TTRAG A+IR  +PP
Sbjct  182  TNDARFLFHPAMKELTLDIASLVFMGHEPGTDHDLVTKVNQAFTTTTRAGGAIIRQPIPP  241

Query  242  FTWWRGLRARELLENYFTARVKERREASGNDLLTVLCQTEDDDGNRFSDADIVNHMIFLM  301
            F WWRGLRAR+LLE+YF+ RVKERR A+GND+LTVLC TEDDDGN F+D DIVNHMIFLM
Sbjct  242  FKWWRGLRARQLLEDYFSERVKERRNATGNDMLTVLCHTEDDDGNSFTDDDIVNHMIFLM  301

Query  302  MAAHDTSTSTATTMAYQLAAHPEWQQRCRDESDRHGDGPLDIESLEQLESLDLVMNESIR  361
            MAAHDTSTST TTM Y +AAHPEWQ+R R+ES R GDGPLDIE+LE+LE+L+L+MNES+R
Sbjct  302  MAAHDTSTSTTTTMVYNMAAHPEWQERAREESTRLGDGPLDIEALEKLETLELIMNESLR  361

Query  362  LVTPVQWAMRQTVRDTELLGYYLPKGTNVIAYPGMNHRLPEIWTDPLTFDPERFTEPRNE  421
            +VTP+ + MRQ VRDTELLG+Y+P GTN+  +PGMNHRLPE+WTDP  FDPERF EPR E
Sbjct  362  MVTPLPFNMRQAVRDTELLGHYIPAGTNITIWPGMNHRLPELWTDPDKFDPERFAEPRAE  421

Query  422  HKRHRYAFTPFGGGVHKCIGMVFDQLEIKTILHRLLRRYRLELSRPDYQPRWDYSAMPIP  481
            HK+HRYAF PFGGG HKCIGMVF QLE+KT++HRLLRRYRLEL+RP YQPRWDY  MPIP
Sbjct  422  HKKHRYAFAPFGGGAHKCIGMVFGQLEVKTVVHRLLRRYRLELARPGYQPRWDYGGMPIP  481

Query  482  MDGMPIVLRP  491
            MDGMPIVLRP
Sbjct  482  MDGMPIVLRP  491


>gi|41409207|ref|NP_962043.1| hypothetical protein MAP3109 [Mycobacterium avium subsp. paratuberculosis 
K-10]
 gi|41398027|gb|AAS05657.1| hypothetical protein MAP_3109 [Mycobacterium avium subsp. paratuberculosis 
K-10]
Length=492

 Score =  742 bits (1915),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 360/490 (74%), Positives = 420/490 (86%), Gaps = 1/490 (0%)

Query  2    ATIHPPAYLLDQAKRRFTPSFNNFPGMSLVEHMLLNTKFPEKKLAEPPPGSGLKPVVGDA  61
            ATI  P YLLDQA+RRFTP+ N  PGM  +E  LL  ++  K LAEPP GSGLKPV+GDA
Sbjct  3    ATISTPQYLLDQARRRFTPTLNTIPGMGAIEKRLLAHEWQTKVLAEPPAGSGLKPVLGDA  62

Query  62   GLPILGHMIEMLRGGPDYLMFLYKTKGPVVFGDSAVLPGVAALGPDAAQVIYSNRNKDYS  121
            GLPILGH+IE+ RGGPDY +FLY+  GP+++ DS ++P V ALGPDA Q ++SNRNKDYS
Sbjct  63   GLPILGHIIELFRGGPDYALFLYRNHGPLIYLDSPIMPAVTALGPDATQAVFSNRNKDYS  122

Query  122  QQGWVPVIGPFFHRGLMLLDFEEHMFHRRIMQEAFVRSRLAGYLEQMDRVVSRVVADDWV  181
            Q+GW PVIGPFF+RGLM+LDF+EHM+HRRIMQEAF RSRL GY+E +DRV + +VAD W 
Sbjct  123  QKGWHPVIGPFFNRGLMMLDFDEHMYHRRIMQEAFTRSRLTGYVEHIDRVATAIVAD-WP  181

Query  182  VNDARFLVYPAMKALTLDIASMVFMGHEPGTDHELVTKVNKAFTITTRAGNAVIRTSVPP  241
             NDARFL +PAMK LTLDIAS+VFMGHEPGTDH+LVT VN+AFT TTRAG A+IR  +PP
Sbjct  182  TNDARFLFHPAMKELTLDIASLVFMGHEPGTDHDLVTTVNQAFTTTTRAGGAIIRQPIPP  241

Query  242  FTWWRGLRARELLENYFTARVKERREASGNDLLTVLCQTEDDDGNRFSDADIVNHMIFLM  301
            F WWRGLRAR+LLE+YF+ RVKERR A+GND+LTVLC TEDDDGN F+D DIVNHMIFLM
Sbjct  242  FKWWRGLRARQLLEDYFSERVKERRNATGNDMLTVLCHTEDDDGNSFTDDDIVNHMIFLM  301

Query  302  MAAHDTSTSTATTMAYQLAAHPEWQQRCRDESDRHGDGPLDIESLEQLESLDLVMNESIR  361
            MAAHDTSTST TTM Y +AAHPEWQ+R R+ES R GDGPLDIE+LE+LE+L+L+MNES+R
Sbjct  302  MAAHDTSTSTTTTMVYNMAAHPEWQERAREESARLGDGPLDIEALEKLETLELIMNESLR  361

Query  362  LVTPVQWAMRQTVRDTELLGYYLPKGTNVIAYPGMNHRLPEIWTDPLTFDPERFTEPRNE  421
            +VTP+ + MRQ VRDTELLG+Y+P GTN+  +PGMNHRLPE+WTDP  FDPERF EPR E
Sbjct  362  MVTPLPFNMRQAVRDTELLGHYIPAGTNITIWPGMNHRLPELWTDPDKFDPERFAEPRAE  421

Query  422  HKRHRYAFTPFGGGVHKCIGMVFDQLEIKTILHRLLRRYRLELSRPDYQPRWDYSAMPIP  481
            HK+HRYAF PFGGG HKCIGMVF QLE+KT++HRLLRRYRLEL+RP YQPRWDY  MPIP
Sbjct  422  HKKHRYAFAPFGGGAHKCIGMVFGQLEVKTVVHRLLRRYRLELARPGYQPRWDYGGMPIP  481

Query  482  MDGMPIVLRP  491
            MDGMPIVLRP
Sbjct  482  MDGMPIVLRP  491


>gi|336459247|gb|EGO38192.1| cytochrome P450 [Mycobacterium avium subsp. paratuberculosis 
S397]
Length=492

 Score =  741 bits (1913),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 359/490 (74%), Positives = 420/490 (86%), Gaps = 1/490 (0%)

Query  2    ATIHPPAYLLDQAKRRFTPSFNNFPGMSLVEHMLLNTKFPEKKLAEPPPGSGLKPVVGDA  61
            ATI  P YLLDQA+RRFTP+ N  PGM  +E  LL  ++  K LAEPP GSGLKPV+GDA
Sbjct  3    ATISTPQYLLDQARRRFTPTLNTIPGMGAIEKRLLAHEWQTKVLAEPPAGSGLKPVLGDA  62

Query  62   GLPILGHMIEMLRGGPDYLMFLYKTKGPVVFGDSAVLPGVAALGPDAAQVIYSNRNKDYS  121
            GLPILGH+IE+ RGGPDY +FLY+  GP+++ DS ++P V A+GPDA Q ++SNRNKDYS
Sbjct  63   GLPILGHIIELFRGGPDYALFLYRNHGPLIYLDSPIMPAVTAVGPDATQAVFSNRNKDYS  122

Query  122  QQGWVPVIGPFFHRGLMLLDFEEHMFHRRIMQEAFVRSRLAGYLEQMDRVVSRVVADDWV  181
            Q+GW PVIGPFF+RGLM+LDF+EHM+HRRIMQEAF RSRL GY+E +DRV + +VAD W 
Sbjct  123  QKGWHPVIGPFFNRGLMMLDFDEHMYHRRIMQEAFTRSRLTGYVEHIDRVATAIVAD-WP  181

Query  182  VNDARFLVYPAMKALTLDIASMVFMGHEPGTDHELVTKVNKAFTITTRAGNAVIRTSVPP  241
             NDARFL +PAMK LTLDIAS+VFMGHEPGTDH+LVT VN+AFT TTRAG A+IR  +PP
Sbjct  182  TNDARFLFHPAMKELTLDIASLVFMGHEPGTDHDLVTTVNQAFTTTTRAGGAIIRQPIPP  241

Query  242  FTWWRGLRARELLENYFTARVKERREASGNDLLTVLCQTEDDDGNRFSDADIVNHMIFLM  301
            F WWRGLRAR+LLE+YF+ RVKERR A+GND+LTVLC TEDDDGN F+D DIVNHMIFLM
Sbjct  242  FKWWRGLRARQLLEDYFSERVKERRNATGNDMLTVLCHTEDDDGNSFTDDDIVNHMIFLM  301

Query  302  MAAHDTSTSTATTMAYQLAAHPEWQQRCRDESDRHGDGPLDIESLEQLESLDLVMNESIR  361
            MAAHDTSTST TTM Y +AAHPEWQ+R R+ES R GDGPLDIE+LE+LE+L+L+MNES+R
Sbjct  302  MAAHDTSTSTTTTMVYNMAAHPEWQERAREESARLGDGPLDIEALEKLETLELIMNESLR  361

Query  362  LVTPVQWAMRQTVRDTELLGYYLPKGTNVIAYPGMNHRLPEIWTDPLTFDPERFTEPRNE  421
            +VTP+ + MRQ VRDTELLG+Y+P GTN+  +PGMNHRLPE+WTDP  FDPERF EPR E
Sbjct  362  MVTPLPFNMRQAVRDTELLGHYIPAGTNITIWPGMNHRLPELWTDPDKFDPERFAEPRAE  421

Query  422  HKRHRYAFTPFGGGVHKCIGMVFDQLEIKTILHRLLRRYRLELSRPDYQPRWDYSAMPIP  481
            HK+HRYAF PFGGG HKCIGMVF QLE+KT++HRLLRRYRLEL+RP YQPRWDY  MPIP
Sbjct  422  HKKHRYAFAPFGGGAHKCIGMVFGQLEVKTVVHRLLRRYRLELARPGYQPRWDYGGMPIP  481

Query  482  MDGMPIVLRP  491
            MDGMPIVLRP
Sbjct  482  MDGMPIVLRP  491


>gi|296171145|ref|ZP_06852593.1| P450 heme-thiolate protein [Mycobacterium parascrofulaceum ATCC 
BAA-614]
 gi|295894281|gb|EFG74036.1| P450 heme-thiolate protein [Mycobacterium parascrofulaceum ATCC 
BAA-614]
Length=492

 Score =  734 bits (1895),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 359/490 (74%), Positives = 418/490 (86%), Gaps = 1/490 (0%)

Query  2    ATIHPPAYLLDQAKRRFTPSFNNFPGMSLVEHMLLNTKFPEKKLAEPPPGSGLKPVVGDA  61
            ATI  P YLLDQA+RRFTP+ N  PGM  VE  LL   +  K LAEPP GSGLKPV GDA
Sbjct  3    ATISTPQYLLDQARRRFTPTLNTIPGMGAVEKRLLAHDWDVKVLAEPPAGSGLKPVTGDA  62

Query  62   GLPILGHMIEMLRGGPDYLMFLYKTKGPVVFGDSAVLPGVAALGPDAAQVIYSNRNKDYS  121
            GLPILGH+IEM RGGPDY + LY+T+GP+ F DS ++P V ALGPDA Q ++SN+NKD+S
Sbjct  63   GLPILGHIIEMFRGGPDYALHLYRTRGPLHFLDSPIMPAVTALGPDATQAVFSNKNKDFS  122

Query  122  QQGWVPVIGPFFHRGLMLLDFEEHMFHRRIMQEAFVRSRLAGYLEQMDRVVSRVVADDWV  181
            Q+GW PVIGPFF+RGLM+LDF+EHM+HRRIMQEAF RSRL GY+E +DRV S +VA+ W 
Sbjct  123  QRGWHPVIGPFFNRGLMMLDFDEHMYHRRIMQEAFTRSRLTGYVEHIDRVASDIVAN-WP  181

Query  182  VNDARFLVYPAMKALTLDIASMVFMGHEPGTDHELVTKVNKAFTITTRAGNAVIRTSVPP  241
             NDARFL +PAMK LTLD+AS+VFMGHEPGTDH LVTKVN+AFTITTRAG A+IR  VPP
Sbjct  182  TNDARFLFHPAMKELTLDVASLVFMGHEPGTDHNLVTKVNQAFTITTRAGGAIIRQPVPP  241

Query  242  FTWWRGLRARELLENYFTARVKERREASGNDLLTVLCQTEDDDGNRFSDADIVNHMIFLM  301
            F WWRGLRAR LLE YF  RVKERR+A+GND+LTVLC TED+DGNRF+D DIVNHMIFLM
Sbjct  242  FKWWRGLRARTLLEEYFADRVKERRQATGNDMLTVLCHTEDEDGNRFTDEDIVNHMIFLM  301

Query  302  MAAHDTSTSTATTMAYQLAAHPEWQQRCRDESDRHGDGPLDIESLEQLESLDLVMNESIR  361
            MAAHDTSTST TTM Y +AA+PEWQ+R R+ES R GDGPLDIE+LE+LE+L+L+MNES+R
Sbjct  302  MAAHDTSTSTTTTMVYNMAANPEWQERAREESARLGDGPLDIEALEKLETLELIMNESLR  361

Query  362  LVTPVQWAMRQTVRDTELLGYYLPKGTNVIAYPGMNHRLPEIWTDPLTFDPERFTEPRNE  421
            +VTP+ + MRQ +RDTELLG+Y+P GTN+  +PGMNHRLPE+WTDP  FDPERF EPR+E
Sbjct  362  MVTPLPFNMRQAIRDTELLGHYIPAGTNITIWPGMNHRLPELWTDPDKFDPERFAEPRSE  421

Query  422  HKRHRYAFTPFGGGVHKCIGMVFDQLEIKTILHRLLRRYRLELSRPDYQPRWDYSAMPIP  481
            HK+HRYAF PFGGG HKCIGMVF QLE+KT++HRLLRRYRLEL+RP Y+P WDY  MPIP
Sbjct  422  HKKHRYAFAPFGGGAHKCIGMVFGQLEVKTVVHRLLRRYRLELARPGYEPHWDYGGMPIP  481

Query  482  MDGMPIVLRP  491
            MDGMPIVLRP
Sbjct  482  MDGMPIVLRP  491


>gi|145224894|ref|YP_001135572.1| cytochrome P450 [Mycobacterium gilvum PYR-GCK]
 gi|315445223|ref|YP_004078102.1| cytochrome P450 [Mycobacterium sp. Spyr1]
 gi|145217380|gb|ABP46784.1| cytochrome P450 [Mycobacterium gilvum PYR-GCK]
 gi|315263526|gb|ADU00268.1| cytochrome P450 [Mycobacterium sp. Spyr1]
Length=493

 Score =  703 bits (1815),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 320/491 (66%), Positives = 392/491 (80%), Gaps = 0/491 (0%)

Query  1    MATIHPPAYLLDQAKRRFTPSFNNFPGMSLVEHMLLNTKFPEKKLAEPPPGSGLKPVVGD  60
            M  I  P YLLDQAKRR  P+    PGM  +E  LL  ++ E  LAEPP GSGLK V GD
Sbjct  1    MTAISTPEYLLDQAKRRLKPTPVTIPGMGAIEKRLLEKQWDEIILAEPPAGSGLKAVRGD  60

Query  61   AGLPILGHMIEMLRGGPDYLMFLYKTKGPVVFGDSAVLPGVAALGPDAAQVIYSNRNKDY  120
             GLPI+ HMIEM RGGPD+++  Y+  GPV +  S VLP V ALGPDA Q ++SNRNKD+
Sbjct  61   NGLPIVAHMIEMFRGGPDFILHQYRKYGPVYYSGSQVLPAVGALGPDATQAVFSNRNKDF  120

Query  121  SQQGWVPVIGPFFHRGLMLLDFEEHMFHRRIMQEAFVRSRLAGYLEQMDRVVSRVVADDW  180
            SQ+ W PVIGPFF  GLML DFE+HM+HRRIMQEAF RSRL GY+E +D+V S V+A+DW
Sbjct  121  SQRAWDPVIGPFFEGGLMLRDFEDHMYHRRIMQEAFTRSRLTGYVEHIDQVASAVIANDW  180

Query  181  VVNDARFLVYPAMKALTLDIASMVFMGHEPGTDHELVTKVNKAFTITTRAGNAVIRTSVP  240
            V +D RFL YPA+K LTLDIAS+VFMGH+ GTD +LVT VN+AFT TTRAGNA++R  VP
Sbjct  181  VADDRRFLFYPAVKELTLDIASVVFMGHKAGTDKQLVTTVNEAFTTTTRAGNAIVRKPVP  240

Query  241  PFTWWRGLRARELLENYFTARVKERREASGNDLLTVLCQTEDDDGNRFSDADIVNHMIFL  300
            P +WWRG+RAR+ LE+YF A + E+R +   D+ +VLC  +D+DG  F+D D+V+HMIFL
Sbjct  241  PLSWWRGIRARKTLEDYFNAGIAEKRRSESTDMFSVLCHAQDEDGQSFTDQDVVSHMIFL  300

Query  301  MMAAHDTSTSTATTMAYQLAAHPEWQQRCRDESDRHGDGPLDIESLEQLESLDLVMNESI  360
            MMAAHDTSTST TTMAY LAA+PEWQ RCR+ES+R GDGPLDIE+LE+LE+ DLV+NE++
Sbjct  301  MMAAHDTSTSTLTTMAYHLAANPEWQDRCREESERIGDGPLDIEALEKLETYDLVINEAL  360

Query  361  RLVTPVQWAMRQTVRDTELLGYYLPKGTNVIAYPGMNHRLPEIWTDPLTFDPERFTEPRN  420
            R+VTP+ +  R+ VRDTELLGYY+P GT ++ +P +NHRLPE+WTDP  FDP RF EPRN
Sbjct  361  RMVTPLPFNFREAVRDTELLGYYIPAGTAIMTWPALNHRLPELWTDPEKFDPARFAEPRN  420

Query  421  EHKRHRYAFTPFGGGVHKCIGMVFDQLEIKTILHRLLRRYRLELSRPDYQPRWDYSAMPI  480
            EHK+HRYAF PFGGG HKCIGMVF QLEIKT++HRLLR+YRLE   P+Y+PR+D+  M +
Sbjct  421  EHKKHRYAFAPFGGGAHKCIGMVFGQLEIKTVMHRLLRKYRLEPVSPNYRPRYDHGGMAV  480

Query  481  PMDGMPIVLRP  491
            P+DGMPIVLRP
Sbjct  481  PIDGMPIVLRP  491


>gi|120403025|ref|YP_952854.1| cytochrome P450 [Mycobacterium vanbaalenii PYR-1]
 gi|119955843|gb|ABM12848.1| cytochrome P450 [Mycobacterium vanbaalenii PYR-1]
Length=493

 Score =  681 bits (1756),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 320/491 (66%), Positives = 392/491 (80%), Gaps = 0/491 (0%)

Query  1    MATIHPPAYLLDQAKRRFTPSFNNFPGMSLVEHMLLNTKFPEKKLAEPPPGSGLKPVVGD  60
            M +I    Y+LDQAKRR  P+    PGM  VE  L +  + +  LAEPP GS LKP++GD
Sbjct  1    MPSISTTDYVLDQAKRRLKPTPVTIPGMGAVEKRLKDKHWDQFVLAEPPAGSDLKPILGD  60

Query  61   AGLPILGHMIEMLRGGPDYLMFLYKTKGPVVFGDSAVLPGVAALGPDAAQVIYSNRNKDY  120
            AGLPI+GHMIE+ RGGPD+++ +Y+  GPV F +S  L  V ALGPDA Q ++SNRNKD+
Sbjct  61   AGLPIIGHMIEIFRGGPDFILEIYRKHGPVYFAESPALSSVMALGPDATQAVFSNRNKDF  120

Query  121  SQQGWVPVIGPFFHRGLMLLDFEEHMFHRRIMQEAFVRSRLAGYLEQMDRVVSRVVADDW  180
            SQ+ W PVIGPFF  GLMLLDF+EHMFHRRIMQEAF RSRL GY+  +D V S V+A+DW
Sbjct  121  SQRAWDPVIGPFFEGGLMLLDFDEHMFHRRIMQEAFTRSRLTGYVSHIDSVASAVLANDW  180

Query  181  VVNDARFLVYPAMKALTLDIASMVFMGHEPGTDHELVTKVNKAFTITTRAGNAVIRTSVP  240
            V ND RFL +PA+K LTLDIAS VFMG   GTD  LVT VN+AFT TTRAGNA++R  VP
Sbjct  181  VANDPRFLFHPAIKELTLDIASEVFMGVPAGTDRALVTTVNQAFTTTTRAGNAIVRKPVP  240

Query  241  PFTWWRGLRARELLENYFTARVKERREASGNDLLTVLCQTEDDDGNRFSDADIVNHMIFL  300
            P TWWRG++AR+ LE+YF++R+ E+R +   D+ +VLC + D+DG  F+D  IV+HMIFL
Sbjct  241  PLTWWRGIKARKTLEDYFSSRIGEKRRSESTDMFSVLCHSADEDGQSFTDDQIVSHMIFL  300

Query  301  MMAAHDTSTSTATTMAYQLAAHPEWQQRCRDESDRHGDGPLDIESLEQLESLDLVMNESI  360
            MMAAHDTSTST TTMAY LAA+PEWQ R R+ES R GDGPLDIE+LE+LE+ DLV+NE++
Sbjct  301  MMAAHDTSTSTMTTMAYHLAANPEWQDRLREESARIGDGPLDIEALEKLETYDLVINEAL  360

Query  361  RLVTPVQWAMRQTVRDTELLGYYLPKGTNVIAYPGMNHRLPEIWTDPLTFDPERFTEPRN  420
            R++TP+ +  RQ +RDT+LLGYY+P GTNV+ +P +NHRLPE+WTDP  FDPERF EPR+
Sbjct  361  RMMTPLPFNFRQAIRDTDLLGYYIPAGTNVVTWPSINHRLPELWTDPEKFDPERFAEPRS  420

Query  421  EHKRHRYAFTPFGGGVHKCIGMVFDQLEIKTILHRLLRRYRLELSRPDYQPRWDYSAMPI  480
            EHK+HRYAF PFGGG HKCIGMVF QLEIKT++HRLL+ YRLEL RPDYQPR+DY  MP+
Sbjct  421  EHKKHRYAFAPFGGGAHKCIGMVFGQLEIKTVVHRLLQNYRLELPRPDYQPRYDYGGMPV  480

Query  481  PMDGMPIVLRP  491
            P+DGMPIVLRP
Sbjct  481  PLDGMPIVLRP  491


>gi|169630504|ref|YP_001704153.1| cytochrome P450 [Mycobacterium abscessus ATCC 19977]
 gi|169242471|emb|CAM63499.1| Probable cytochrome P450 [Mycobacterium abscessus]
Length=492

 Score =  681 bits (1756),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 325/492 (67%), Positives = 399/492 (82%), Gaps = 3/492 (0%)

Query  1    MATIHPPAYLLDQAKRRFTPSFNNFPGMSLVEHMLLNTKFPEKKLAEPPPGSGLKPVVGD  60
            MATI    YL+DQAKRR  P+ N  PGM  +E+ L N ++P  +LA PPPGSGLKPV+GD
Sbjct  1    MATISSTDYLIDQAKRRL-PTMNTLPGMGYIENYLNNREWPMTELAAPPPGSGLKPVMGD  59

Query  61   AGLPILGHMIEMLRGGPDYLMFLYKTKGPVVFGDSAVLPGVAALGPDAAQVIYSNRNKDY  120
             GLP+LGHM+EM RGG D+++ +Y+ +GPV +  + +   VAALGPDA Q ++SN NKD+
Sbjct  60   QGLPMLGHMVEMFRGGIDWVLNMYQERGPVSWTQTPIGKIVAALGPDATQAVFSNANKDF  119

Query  121  SQQGWVPVIGPFFHRGLMLLDFEEHMFHRRIMQEAFVRSRLAGYLEQMDRVVSRVVADDW  180
            SQQGWVPVIGPFF+RGLMLLDF+EH  HR IMQ+AF+RSRLAGY+EQ+D V S +VA  W
Sbjct  120  SQQGWVPVIGPFFNRGLMLLDFQEHREHRLIMQQAFLRSRLAGYVEQIDAVASEIVAQ-W  178

Query  181  VVNDARFLVYPAMKALTLDIASMVFMGHEPGTDHELVTKVNKAFTITTRAGNAVIRTSVP  240
              ND RFL YPA+K LTLD+AS+VFMG+EP   HE + KVNKAF  TTRAG A+ R  +P
Sbjct  179  PTNDNRFLFYPAIKELTLDVASVVFMGNEPHAQHERLEKVNKAFVATTRAGGAIFRFGLP  238

Query  241  PFTWWRGLRARELLENYFTARVK-ERREASGNDLLTVLCQTEDDDGNRFSDADIVNHMIF  299
            PF WW+GL+ R+LLE YF  RV   R++  G D+LT LC  E D+G+ F+D DIVNHMIF
Sbjct  239  PFKWWQGLQGRKLLEEYFAERVGIARQKTEGADMLTALCHAETDEGDAFTDTDIVNHMIF  298

Query  300  LMMAAHDTSTSTATTMAYQLAAHPEWQQRCRDESDRHGDGPLDIESLEQLESLDLVMNES  359
            LMMAAHDT+TST TTMAY LAA+PEWQ+R RDESDR GDGPLDI+SLE+LESLDLVMNE+
Sbjct  299  LMMAAHDTTTSTTTTMAYYLAANPEWQERVRDESDRLGDGPLDIDSLEKLESLDLVMNEA  358

Query  360  IRLVTPVQWAMRQTVRDTELLGYYLPKGTNVIAYPGMNHRLPEIWTDPLTFDPERFTEPR  419
            +RLVTP+ + +R TVRDT+LLG+++P GT +  +PGMNHRLPE+WT+P  FDP+RF+EPR
Sbjct  359  LRLVTPLPFNIRSTVRDTDLLGFHIPAGTMINIWPGMNHRLPELWTEPDKFDPDRFSEPR  418

Query  420  NEHKRHRYAFTPFGGGVHKCIGMVFDQLEIKTILHRLLRRYRLELSRPDYQPRWDYSAMP  479
            NEHKRHRYAF+PFGGG HKCIGMVF QLEIK ++HRLLRRYR EL+ P YQP+WDY+ MP
Sbjct  419  NEHKRHRYAFSPFGGGAHKCIGMVFGQLEIKAVMHRLLRRYRFELAHPHYQPKWDYAGMP  478

Query  480  IPMDGMPIVLRP  491
            +P+DGMPI+LRP
Sbjct  479  LPIDGMPIILRP  490


>gi|333991433|ref|YP_004524047.1| cytochrome P450 [Mycobacterium sp. JDM601]
 gi|333487401|gb|AEF36793.1| cytochrome P450 136A2 Cyp136A2 [Mycobacterium sp. JDM601]
Length=491

 Score =  681 bits (1756),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 334/491 (69%), Positives = 401/491 (82%), Gaps = 1/491 (0%)

Query  1    MATIHPPAYLLDQAKRRFTPSFNNFPGMSLVEHMLLNTKFPEKKLAEPPPGSGLKPVVGD  60
            M T+  P YLLDQA+RRFTP+ N  PGM  +E  LL   + +K LAEPP GSGLKP+VGD
Sbjct  1    MTTMTTPQYLLDQARRRFTPTLNTIPGMGAIEKRLLTVDWKQKTLAEPPAGSGLKPIVGD  60

Query  61   AGLPILGHMIEMLRGGPDYLMFLYKTKGPVVFGDSAVLPGVAALGPDAAQVIYSNRNKDY  120
            +GLP+LGH++EM RGGPD+ M +Y+  GPV F +S +L  V ALGPDA + +++NR KDY
Sbjct  61   SGLPVLGHIVEMFRGGPDFAMHIYRKHGPVYFAESPILSSVVALGPDATETVFANRKKDY  120

Query  121  SQQGWVPVIGPFFHRGLMLLDFEEHMFHRRIMQEAFVRSRLAGYLEQMDRVVSRVVADDW  180
            S  GW+PVIGPFF+RGLMLLDFEEH+ H+RIMQ AF R RLA Y+E MDRV S +VA  W
Sbjct  121  STTGWIPVIGPFFNRGLMLLDFEEHLAHKRIMQGAFTRPRLASYVEDMDRVASALVAK-W  179

Query  181  VVNDARFLVYPAMKALTLDIASMVFMGHEPGTDHELVTKVNKAFTITTRAGNAVIRTSVP  240
              ND RFL YPA+K LTLD+AS+VFMG +   D + V KVN AF  TTRAG A+IRTSVP
Sbjct  180  PTNDPRFLFYPAVKELTLDVASVVFMGMDLRDDQKTVAKVNHAFEQTTRAGGAIIRTSVP  239

Query  241  PFTWWRGLRARELLENYFTARVKERREASGNDLLTVLCQTEDDDGNRFSDADIVNHMIFL  300
            PF WWRGL+ R++LE+YFT RV+ERR   G D+LTVLC T D+DGN FSDADIVNHMIFL
Sbjct  240  PFKWWRGLQGRKVLEDYFTQRVRERRNVEGTDMLTVLCHTADEDGNTFSDADIVNHMIFL  299

Query  301  MMAAHDTSTSTATTMAYQLAAHPEWQQRCRDESDRHGDGPLDIESLEQLESLDLVMNESI  360
            MMAAHDT+TST TTMAY LAA+PEWQ+R R+ES R GD PLDIE+LE+LE+LDLVM+ES+
Sbjct  300  MMAAHDTTTSTLTTMAYHLAANPEWQERAREESARLGDSPLDIEALEKLETLDLVMDESL  359

Query  361  RLVTPVQWAMRQTVRDTELLGYYLPKGTNVIAYPGMNHRLPEIWTDPLTFDPERFTEPRN  420
            RLVTP+ + MRQ VRDTELLG+Y+P GTNV  +PGMNH LPE++T+P  FDPERF EPR+
Sbjct  360  RLVTPLPFNMRQAVRDTELLGHYVPAGTNVTLWPGMNHWLPELYTNPRQFDPERFLEPRS  419

Query  421  EHKRHRYAFTPFGGGVHKCIGMVFDQLEIKTILHRLLRRYRLELSRPDYQPRWDYSAMPI  480
            EHK+HRYAF PFGGG HKCIGMV+ +LE+KT++HRLLRRYRLELSRP Y+P+WDY+ MP+
Sbjct  420  EHKKHRYAFAPFGGGAHKCIGMVYGRLEVKTVMHRLLRRYRLELSRPGYRPKWDYAGMPL  479

Query  481  PMDGMPIVLRP  491
            PMDGMPIVLRP
Sbjct  480  PMDGMPIVLRP  490


>gi|118468969|ref|YP_886639.1| cytochrome p450 [Mycobacterium smegmatis str. MC2 155]
 gi|118471223|ref|YP_885410.1| cytochrome p450 [Mycobacterium smegmatis str. MC2 155]
 gi|118170256|gb|ABK71152.1| cytochrome p450 [Mycobacterium smegmatis str. MC2 155]
 gi|118172510|gb|ABK73406.1| cytochrome p450 [Mycobacterium smegmatis str. MC2 155]
Length=494

 Score =  679 bits (1753),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 319/490 (66%), Positives = 392/490 (80%), Gaps = 0/490 (0%)

Query  2    ATIHPPAYLLDQAKRRFTPSFNNFPGMSLVEHMLLNTKFPEKKLAEPPPGSGLKPVVGDA  61
             TI  P YLLDQA+RRFTP+ N  PGM  +E  L   ++ +   + PP GSGLKP++GD+
Sbjct  3    TTISTPRYLLDQARRRFTPTPNTIPGMGAIEKRLKRKQWDQFVFSTPPAGSGLKPIMGDS  62

Query  62   GLPILGHMIEMLRGGPDYLMFLYKTKGPVVFGDSAVLPGVAALGPDAAQVIYSNRNKDYS  121
            GLP+LGHMIE+ RGGPD+++  Y+  GP+ +  S  L  V ALGPDA Q ++SNRNKDYS
Sbjct  63   GLPVLGHMIEIFRGGPDFILEQYRRNGPIHYAYSPALSSVMALGPDATQTVFSNRNKDYS  122

Query  122  QQGWVPVIGPFFHRGLMLLDFEEHMFHRRIMQEAFVRSRLAGYLEQMDRVVSRVVADDWV  181
            Q+ W PVIGPFF  GLMLLDF+EHM+HRRIMQ+AF RSRL GY+  +D V S+V+A+DWV
Sbjct  123  QRAWDPVIGPFFEGGLMLLDFDEHMYHRRIMQDAFTRSRLTGYIPHIDSVASQVLANDWV  182

Query  182  VNDARFLVYPAMKALTLDIASMVFMGHEPGTDHELVTKVNKAFTITTRAGNAVIRTSVPP  241
             +D RFL YPA+K LTLDIAS VFMG   GTD +LVT VN AFT TTRAGNA++RT VPP
Sbjct  183  SDDPRFLFYPAIKELTLDIASEVFMGVPAGTDKKLVTTVNHAFTTTTRAGNAIVRTPVPP  242

Query  242  FTWWRGLRARELLENYFTARVKERREASGNDLLTVLCQTEDDDGNRFSDADIVNHMIFLM  301
              WWRG++AR+ LE+YF +R+ E+R A   D+ +VLC + D+DG  F+D  IV+HMIFLM
Sbjct  243  LKWWRGIQARKTLEDYFLSRIDEKRRAESTDMFSVLCHSADEDGQTFTDDQIVSHMIFLM  302

Query  302  MAAHDTSTSTATTMAYQLAAHPEWQQRCRDESDRHGDGPLDIESLEQLESLDLVMNESIR  361
            MAAHDTSTST TTMAY LAA+PEWQ R RDES+R GDGPLDIE+LE+LE+ DLV+NE++R
Sbjct  303  MAAHDTSTSTMTTMAYHLAANPEWQDRLRDESERIGDGPLDIEALEKLETYDLVINEALR  362

Query  362  LVTPVQWAMRQTVRDTELLGYYLPKGTNVIAYPGMNHRLPEIWTDPLTFDPERFTEPRNE  421
            ++TP+ +  RQ VRDTELLGY++P GTNV+ +P +NHRLPE+WTDP  FDPERF EPR+E
Sbjct  363  MMTPLPFNFRQAVRDTELLGYFIPAGTNVVTWPSINHRLPELWTDPEKFDPERFAEPRSE  422

Query  422  HKRHRYAFTPFGGGVHKCIGMVFDQLEIKTILHRLLRRYRLELSRPDYQPRWDYSAMPIP  481
            HK+HRYAF PFGGG HKCIGMVF QLEIKT++HRLLR+YRLEL RP Y PR+DY  MP+P
Sbjct  423  HKKHRYAFAPFGGGAHKCIGMVFGQLEIKTVMHRLLRQYRLELPRPGYTPRYDYGGMPVP  482

Query  482  MDGMPIVLRP  491
            +DGMPIVLRP
Sbjct  483  IDGMPIVLRP  492


>gi|296395038|ref|YP_003659922.1| cytochrome P450 [Segniliparus rotundus DSM 44985]
 gi|296182185|gb|ADG99091.1| cytochrome P450 [Segniliparus rotundus DSM 44985]
Length=489

 Score =  609 bits (1570),  Expect = 4e-172, Method: Compositional matrix adjust.
 Identities = 294/477 (62%), Positives = 361/477 (76%), Gaps = 6/477 (1%)

Query  20   PSFNNFPGMSLVEHMLL-NTKFPEKKLAEPPPGSGLKPVVGDAGLPILGHMIEMLRGGPD  78
            P  +  PG+  VE  LL  ++ P   LAEPPPGSGLKPV+GD GLP+LGH IE +RGG  
Sbjct  11   PRISTLPGLGAVERRLLEKSRPPNVVLAEPPPGSGLKPVLGDNGLPLLGHSIEFMRGGSA  70

Query  79   YLMFLYKTKGPVVFGDSAVLPGVAALGPDAAQVIYSNRNKDYSQQGWVPVIGPFFHRGLM  138
            Y+  +Y+T+GPV F  +  +  V ALGPDA Q +++NR K++SQQGW P+IGPFFHRGLM
Sbjct  71   YIEHVYRTRGPVSFQTNFGITMVTALGPDATQAVFTNREKEFSQQGWTPIIGPFFHRGLM  130

Query  139  LLDFEEHMFHRRIMQEAFVRSRLAGYLEQMDRVVSRVVADDWVVNDARFLVYPAMKALTL  198
            LLD  EH+ HR IMQEAF RS L+GY+E +D V + VV   W  ND  F  + A K LTL
Sbjct  131  LLDHPEHLAHRHIMQEAFTRSALSGYVEHIDEVATEVVRG-WPRNDPAFQFHAAAKDLTL  189

Query  199  DIASMVFMGHEPGT-DHELVTKVNKAFTITTRAGNAVIRTSVPPFTW--W-RGLRARELL  254
            DIA++VFMG + GT DH  +++VN AF  TTRAG A IR  VP   W  W +GL  R LL
Sbjct  190  DIAAVVFMGAQHGTIDHAELSRVNTAFIDTTRAGGAFIRRKVPGMPWLKWNKGLAGRTLL  249

Query  255  ENYFTARVKERREASGNDLLTVLCQTEDDDGNRFSDADIVNHMIFLMMAAHDTSTSTATT  314
            E +F  R++ RR + G D+LTVLC     +G  F+D DIV+HMIFLMMAAHDTSTST TT
Sbjct  250  ERFFAERIQGRRGSEGKDMLTVLCNAVTKEGQCFTDDDIVSHMIFLMMAAHDTSTSTCTT  309

Query  315  MAYQLAAHPEWQQRCRDESDRHGDGPLDIESLEQLESLDLVMNESIRLVTPVQWAMRQTV  374
            MAY LAAHPEWQ+R RDES R GDGPLDI++L++LESLDL+MNES+RLVTP+ +  R TV
Sbjct  310  MAYYLAAHPEWQERARDESARLGDGPLDIDALDKLESLDLIMNESLRLVTPLPFNFRSTV  369

Query  375  RDTELLGYYLPKGTNVIAYPGMNHRLPEIWTDPLTFDPERFTEPRNEHKRHRYAFTPFGG  434
            RD +L+G+++P  + +I  PGMNHRL E+WT+P TFDPERF EPRNEHKRHRYAF+PFGG
Sbjct  370  RDIDLMGHHVPANSIIITQPGMNHRLAELWTEPDTFDPERFAEPRNEHKRHRYAFSPFGG  429

Query  435  GVHKCIGMVFDQLEIKTILHRLLRRYRLELSRPDYQPRWDYSAMPIPMDGMPIVLRP  491
            G HKCIGMVF QLEIK I+HR+LR YR+EL+ PDYQPRWD+  MP+P+DGMP+VLRP
Sbjct  430  GAHKCIGMVFGQLEIKAIMHRILREYRIELASPDYQPRWDHGGMPVPIDGMPLVLRP  486


>gi|317508965|ref|ZP_07966598.1| cytochrome P450 [Segniliparus rugosus ATCC BAA-974]
 gi|316252730|gb|EFV12167.1| cytochrome P450 [Segniliparus rugosus ATCC BAA-974]
Length=495

 Score =  592 bits (1526),  Expect = 5e-167, Method: Compositional matrix adjust.
 Identities = 289/477 (61%), Positives = 354/477 (75%), Gaps = 6/477 (1%)

Query  20   PSFNNFPGMSLVEHMLLNTKF-PEKKLAEPPPGSGLKPVVGDAGLPILGHMIEMLRGGPD  78
            P  +  PG++ VE  LL   + P   LAEPPPGSGLKPV GD GLP+LGH +E +RGG  
Sbjct  11   PRISTLPGLAAVERKLLAQPYRPTAVLAEPPPGSGLKPVRGDNGLPLLGHAVEFMRGGSA  70

Query  79   YLMFLYKTKGPVVFGDSAVLPGVAALGPDAAQVIYSNRNKDYSQQGWVPVIGPFFHRGLM  138
            Y+  LY+T+GPV F  +  +  VAALGPDA Q +++NR K ++QQGWV +IGPFF RGLM
Sbjct  71   YMEHLYRTRGPVSFQTNFGITMVAALGPDATQALFTNREKQFAQQGWVTIIGPFFRRGLM  130

Query  139  LLDFEEHMFHRRIMQEAFVRSRLAGYLEQMDRVVSRVVADDWVVNDARFLVYPAMKALTL  198
            LLDF EH+ HR IMQEAF R+ LAGY+E +D V + VV  +W  +   F V+ A K LTL
Sbjct  131  LLDFPEHLAHRHIMQEAFTRAALAGYVEHIDAVATDVV-RNWPKDGRAFRVHDATKELTL  189

Query  199  DIASMVFMGHEPG-TDHELVTKVNKAFTITTRAGNAVIRTSVPPFTW--W-RGLRARELL  254
            DIAS+VFMG   G   H  + +VN AF  TTRAG A  R   P   W  W +GL  R+LL
Sbjct  190  DIASVVFMGARHGEIGHAELAEVNTAFLNTTRAGGAFFRRPAPGMPWLKWNKGLAGRKLL  249

Query  255  ENYFTARVKERREASGNDLLTVLCQTEDDDGNRFSDADIVNHMIFLMMAAHDTSTSTATT  314
            E +F  R+   R A G D+LTVLC T  +DG  F+D DIV+HMIFLMMAAHDTSTST TT
Sbjct  250  ERFFAERIPAHRGAEGKDMLTVLCNTVTEDGMSFADDDIVSHMIFLMMAAHDTSTSTLTT  309

Query  315  MAYQLAAHPEWQQRCRDESDRHGDGPLDIESLEQLESLDLVMNESIRLVTPVQWAMRQTV  374
            MAY LAA+PEWQ R RDES R GDGPLDI++LE+LE+LDLVM+ES+RLVTP+ +  R TV
Sbjct  310  MAYYLAANPEWQDRARDESARLGDGPLDIDALEKLETLDLVMHESLRLVTPLPFNFRNTV  369

Query  375  RDTELLGYYLPKGTNVIAYPGMNHRLPEIWTDPLTFDPERFTEPRNEHKRHRYAFTPFGG  434
            RD +LLG+++P+GT ++ +P MNHRLPEIWT+P  FDP+RF EPRNEHKRHRYAF PFGG
Sbjct  370  RDVDLLGHHVPEGTTILTHPAMNHRLPEIWTEPEKFDPDRFAEPRNEHKRHRYAFAPFGG  429

Query  435  GVHKCIGMVFDQLEIKTILHRLLRRYRLELSRPDYQPRWDYSAMPIPMDGMPIVLRP  491
            G HKCIGM F QLEIK I+HR+LR YR+ L+ PDYQP+WDY+ MP+P+DGMP+ LRP
Sbjct  430  GAHKCIGMTFGQLEIKAIMHRVLREYRIGLTSPDYQPKWDYAGMPLPVDGMPLALRP  486


>gi|300784780|ref|YP_003765071.1| cytochrome P450 [Amycolatopsis mediterranei U32]
 gi|299794294|gb|ADJ44669.1| cytochrome P450 [Amycolatopsis mediterranei U32]
Length=486

 Score =  477 bits (1228),  Expect = 2e-132, Method: Compositional matrix adjust.
 Identities = 243/480 (51%), Positives = 315/480 (66%), Gaps = 6/480 (1%)

Query  13   QAKRRFTPSFNNFPGMSLVEHMLLNTKFPEKKLAEPPPGSGLKPVVGDAGLPILGHMIEM  72
            +A R   P+    P    V+   L +++P ++LA PP GSGLKPV+GDAG P++GHM+EM
Sbjct  13   EALRERVPTLTALPLPPKVDERWLRSRWPVEELATPPAGSGLKPVLGDAGPPVVGHMLEM  72

Query  73   LRGGPDYLMFLYKTKGPVVFGDSAVLPGVAALGPDAAQVIYSNRNKDYSQQGWVPVIGPF  132
            +R GP + +  Y+  GPV +        VA  GP+A Q+   N++K +SQ+GW   I  F
Sbjct  73   MRFGPAFGLRRYELYGPVSWTGGFGRRIVALSGPEATQIALVNKDKAFSQEGWKFFIEKF  132

Query  133  FHRGLMLLDFEEHMFHRRIMQEAFVRSRLAGYLEQMDRVVSRVVADDWVVNDARFLVYPA  192
            F RGLML+DF EH  HRRIMQEAF R RLAGY+ +M   +   VA  W  ++ R  +Y A
Sbjct  133  FERGLMLMDFGEHHLHRRIMQEAFTRPRLAGYVGEMGPALREGVAS-WGSSE-RPRLYWA  190

Query  193  MKALTLDIASMVFMGHEPGTDHELVTKVNKAFTITTRAGNAVIRTSVPPFTWWRGLRARE  252
            +K LTLD+A+ VFMG   G D     ++N+AF  + RAG A +R  VP   W  GL  R+
Sbjct  191  LKQLTLDVATRVFMGMRSGDD---AARINRAFVSSVRAGTAFVRFPVPGGRWSAGLHGRK  247

Query  253  LLENYFTARVKERREASGNDLLTVLCQTEDDDGNRFSDADIVNHMIFLMMAAHDTSTSTA  312
            +LE YF   +  +R + G+DL   LCQ    DG+RFSD D+VNHMIFLMMAAHDT+T T+
Sbjct  248  VLERYFGETLPAKRRSGGDDLFAALCQATTKDGDRFSDTDVVNHMIFLMMAAHDTTTITS  307

Query  313  TTMAYQLAAHPEWQQRCRDESDRHGDGPLDIESLEQLESLDLVMNESIRLVTPVQWAMRQ  372
            + MAY LA HPEWQ+R R ES   GD   DI +LE+LE+LDLVM E++RLV PV    RQ
Sbjct  308  SAMAYYLAKHPEWQERARAESLALGDDLPDIAALERLETLDLVMKEALRLVAPVPSLTRQ  367

Query  373  TVRDTELLGYYLPKGTNVIAYPGMNHRLPEIWTDPLTFDPERFTEPRNEHKRHRYAFTPF  432
            TV+DTE+LG+Y+P GT V   P +NH  PE WT+P  FDPERF EPR E K HR A+ PF
Sbjct  368  TVKDTEVLGHYIPAGTLVGVSPTVNHFTPECWTNPFEFDPERFAEPRREDKSHRMAWMPF  427

Query  433  GGGVHKCIGMVFDQLEIKTILHRLLRRYRLELSRPDYQPRWDYSAMPIPMDGMPIVLRPR  492
            GGG HKCIG+ F  LE+K ++H LLR YR  +    Y  RWDY ++P+P DG+P+ L PR
Sbjct  428  GGGAHKCIGLHFGSLEVKLLMHELLRAYRWSVPE-SYTARWDYVSLPVPADGLPVHLAPR  486


>gi|302525962|ref|ZP_07278304.1| cytochrome P450 [Streptomyces sp. AA4]
 gi|302434857|gb|EFL06673.1| cytochrome P450 [Streptomyces sp. AA4]
Length=505

 Score =  457 bits (1175),  Expect = 3e-126, Method: Compositional matrix adjust.
 Identities = 240/486 (50%), Positives = 306/486 (63%), Gaps = 15/486 (3%)

Query  11   LDQAKRRFTPSFNNFPGMSLVEHMLLNTKFPEKKLAEPPPGSGLKPVVGDAGLPILGHMI  70
            L +  R   P     P     +   L  ++P ++LA PP GSGLKPV+GD G P++GH +
Sbjct  31   LSENLRGRMPPLTAIPLPRKFDERWLGARWPVRELAAPPAGSGLKPVLGDDGPPLIGHTL  90

Query  71   EMLRGGPDYLMFLYKTKGPV----VFGDSAVLPGVAALGPDAAQVIYSNRNKDYSQQGWV  126
            + +R G D+ +  ++  GPV    VFG   V       GP+A Q    N++K +SQ+GW 
Sbjct  91   DGMRFGLDFSLHRFEQFGPVSWMGVFGQRIV----TLSGPEATQAALINKDKAFSQEGWK  146

Query  127  PVIGPFFHRGLMLLDFEEHMFHRRIMQEAFVRSRLAGYLEQMDRVVSRVVADDWVVNDAR  186
              I  FF RGLMLLDF EH  HRRIMQEAF R RL GY+ QM   +   VA    +   R
Sbjct  147  FFIERFFERGLMLLDFGEHHLHRRIMQEAFTRDRLRGYVAQMGPALREGVA---ALPSGR  203

Query  187  FLVYPAMKALTLDIASMVFMGHEPGTDHELVTKVNKAFTITTRAGNAVIRTSVPPFTWWR  246
              +Y A K LTLD+A+ VFMG     D E   ++N+AF    RAG AV+R  VP   W  
Sbjct  204  PQLYWAFKQLTLDVATQVFMGMRSAADAE---RINRAFVAAVRAGTAVVRYPVPGGRWAA  260

Query  247  GLRARELLENYFTARVKERREASGNDLLTVLCQTEDDDGNRFSDADIVNHMIFLMMAAHD  306
            GLR R  LE YF   +  +R+A G+DL + LC    +DG+RFSDADIVNHMIFLMMAAHD
Sbjct  261  GLRGRRTLERYFGENLAAKRDADGDDLFSALCHAVSEDGDRFSDADIVNHMIFLMMAAHD  320

Query  307  TSTSTATTMAYQLAAHPEWQQRCRDESDRHGDGPLDIESLEQLESLDLVMNESIRLVTPV  366
            T+T TA+ MAY LA HPEWQ+R R+ES R GD   D+E+LE LE+LDLVM E++RL  PV
Sbjct  321  TTTITASAMAYYLAKHPEWQERAREESLRLGDDLPDLEALESLETLDLVMKEALRLRAPV  380

Query  367  QWAMRQTVRDTELLGYYLPKGTNVIAYPGMNHRLPEIWTDPLTFDPERFTEPRNEHKRHR  426
                R+T +DT +LG+YLP+GT V   P +NH  PE WTDPL FDPERF   R E K HR
Sbjct  381  PSLARKTTKDTAVLGHYLPEGTMVAVSPTLNHYSPEHWTDPLRFDPERFGPDRREDKSHR  440

Query  427  YAFTPFGGGVHKCIGMVFDQLEIKTILHRLLRRYRLELSRPDYQPRWDYSAMPIPMDGMP  486
            +A+ PFGGG HKCIG+ F  LE+K ++H LLR +R  +   DY  +WDY ++P+P DG+P
Sbjct  441  FAWMPFGGGAHKCIGLQFGGLEVKALMHELLRAHRWSVPE-DYVAKWDYVSLPVPADGLP  499

Query  487  IVLRPR  492
              L  R
Sbjct  500  ARLAYR  505


>gi|226349657|ref|YP_002776771.1| cytochrome P450 [Rhodococcus opacus B4]
 gi|226245572|dbj|BAH55919.1| cytochrome P450 [Rhodococcus opacus B4]
Length=486

 Score =  450 bits (1157),  Expect = 3e-124, Method: Compositional matrix adjust.
 Identities = 235/491 (48%), Positives = 311/491 (64%), Gaps = 11/491 (2%)

Query  4    IHPPAYLLDQAKRRFTPSFNNFPGMSLVEHML--LNTKFPEKKLAEPPPGSGLKPVVGDA  61
            IH P   LD+A+ R + S    P    +E+ L   + K+P + LAEPP GSGLKPV GD 
Sbjct  5    IHAP---LDKARERVS-SVVMLPAPRRIENALRSFSHKWPTRHLAEPPSGSGLKPVEGDR  60

Query  62   GLPILGHMIEMLRGGPDYLMFLYKTKGPVVFGDSAVLPGVAALGPDAAQVIYSNRNKDYS  121
            GLP+LGH ++ +R G D+    Y   GPV +  +     V   GPDA Q + +N++K +S
Sbjct  61   GLPLLGHTLDYIRFGSDFTRDRYNQFGPVCWMGAFGTRMVIVSGPDATQHVLTNKDKAFS  120

Query  122  QQGWVPVIGPFFHRGLMLLDFEEHMFHRRIMQEAFVRSRLAGYLEQMDRVVSRVVADDWV  181
            Q GW  +I  FFHRGLML+ F+EH  HRRIMQEAF R RLAGY  Q+   V   V   W 
Sbjct  121  QDGWTYLIDKFFHRGLMLMSFDEHRMHRRIMQEAFTRDRLAGYANQVGPCVRENVPT-WP  179

Query  182  VNDARFLVYPAMKALTLDIASMVFMGHEPGTDHELVTKVNKAFTITTRAGNAVIRTSVPP  241
              D+   +YP +K LTLDIA+ VFMG   G   E    +N+AF  T RA ++++R  +P 
Sbjct  180  -TDSTLRIYPRLKNLTLDIATEVFMGGCGGG--EDAAAINQAFVATVRAASSIVRAPLPA  236

Query  242  FTWWRGLRARELLENYFTARVKERREASGNDLLTVLCQTEDDDGNRFSDADIVNHMIFLM  301
              W  G++ R +LE+YF   + E R   GNDL   LC     DG RF+D D+++HMIFLM
Sbjct  237  TRWRAGVKGRRVLEDYFARHLPETRSGDGNDLFAGLCHATTADGERFTDDDVISHMIFLM  296

Query  302  MAAHDTSTSTATTMAYQLAAHPEWQQRCRDESDRHGDGPLDIESLEQLESLDLVMNESIR  361
            MAAHDTST T    AY LA +P WQQ+ RDESD  GD   DI++LE L++LDL++ E++R
Sbjct  297  MAAHDTSTITTAACAYYLAKNPAWQQQARDESDALGDDLPDIDALEGLQTLDLIIKETLR  356

Query  362  LVTPVQWAMRQTVRDTELLGYYLPKGTNVIAYPGMNHRLPEIWTDPLTFDPERFTEPRNE  421
            LV PV   MR+TV DT++LG+Y+P  T V   P +NH + + WT+P TFDP RF   R E
Sbjct  357  LVAPVPIVMRKTVADTDVLGHYIPADTLVAVAPAVNHFVEDYWTNPDTFDPNRFAPDRQE  416

Query  422  HKRHRYAFTPFGGGVHKCIGMVFDQLEIKTILHRLLRRYRLELSRPDYQPRWDYSAMPIP  481
             + HR+A+ PFGGGVHKCIG+ F  LE+K ILH +LR Y   +   DY  RWD +++P+P
Sbjct  417  DQSHRFAWIPFGGGVHKCIGLHFGTLEVKAILHEMLRVYTWTVP-DDYTVRWDNTSLPVP  475

Query  482  MDGMPIVLRPR  492
            +DG+PI L  R
Sbjct  476  VDGLPIQLSRR  486


>gi|333920600|ref|YP_004494181.1| cytochrome P450 [Amycolicicoccus subflavus DQS3-9A1]
 gi|333482821|gb|AEF41381.1| Cytochrome P450 [Amycolicicoccus subflavus DQS3-9A1]
Length=486

 Score =  441 bits (1135),  Expect = 1e-121, Method: Compositional matrix adjust.
 Identities = 239/479 (50%), Positives = 302/479 (64%), Gaps = 5/479 (1%)

Query  11   LDQAKRRFTPSFNNFPGMSLVEHMLLNTKFPEKKLAEPPPGSGLKPVVGDAGLPILGHMI  70
            +  A  R  P+    PG  L+   L +     +  A PP  SGLKPV+GDAGLP+LGH  
Sbjct  10   IKHAVARHKPTIATLPGTRLIADTLEHHHRRAEPFATPPADSGLKPVLGDAGLPVLGHTF  69

Query  71   EMLRGGPDYLMFLYKTKGPVVFGDSAVLPGVAALGPDAAQVIYSNRNKDYSQQGWVPVIG  130
            E++R GP+Y M  Y   GPV + +     GVA  GP+A Q +  NR+  Y+Q GW  +I 
Sbjct  70   ELMRLGPEYQMRRYNQLGPVSWANVFGRRGVAIAGPEATQAVLVNRDNTYTQGGWRYLID  129

Query  131  PFFHRGLMLLDFEEHMFHRRIMQEAFVRSRLAGYLEQMDRVVSRVVADDWVVNDARFLVY  190
             FFHRGLMLLD +EH +HRRIMQ AF + RL GY+   D VV   V       D    +Y
Sbjct  130  AFFHRGLMLLDADEHRYHRRIMQAAFTKERLEGYVAVADEVVDAQVWKFTRGGDVE--LY  187

Query  191  PAMKALTLDIASMVFMGHEPGTDHELVTKVNKAFTITTRAGNAVIRTSVPPFTWWRGLRA  250
            P +K LTL++A+ VFM     +D ++VTK+N AF    R G A++R  VP   W RGLR 
Sbjct  188  PTLKQLTLEVATRVFMDAGKQSD-DVVTKLNDAFIACVRGGTAIVRYPVPGGRWARGLRG  246

Query  251  RELLENYFTARVKERREASGNDLLTVLCQTEDDDGNRFSDADIVNHMIFLMMAAHDTSTS  310
            R  LE+YF   +  +R  +  DL   LC    +DG  FSD DIVNHMIFLMMAAHDT+T 
Sbjct  247  RRTLESYFREHLPAKRRENSRDLFAALCHATSEDGETFSDDDIVNHMIFLMMAAHDTATI  306

Query  311  TATTMAYQLAAHPEWQQRCRDESDRHGDGPLDIESLEQLESLDLVMNESIRLVTPVQWAM  370
            TAT  AY LA HPEWQ++ R E   H DGP+    L+ L +LD V++ES+RLV PV   M
Sbjct  307  TATATAYHLAKHPEWQEKVRAEVAAH-DGPVSPSYLDGLMTLDNVISESLRLVAPVPAFM  365

Query  371  RQTVRDTELLGYYLPKGTNVIAYPGMNHRLPEIWTDPLTFDPERFTEPRNEHKRHRYAFT  430
            R+T +DTE+LG+Y+PKGT ++  P +NH LPE WT+P  FDPERF   R E K+H + F 
Sbjct  366  RETTKDTEILGFYIPKGTFLLVDPWVNHLLPEYWTEPTRFDPERFAPHRREDKQHPFLFV  425

Query  431  PFGGGVHKCIGMVFDQLEIKTILHRLLRRYRLELSRPDYQPRWDYSAMPIPMDGMPIVL  489
            PFGGG H+CIGM F  LE+KTILH LLR YRLEL +P Y   WD S++P P DG+PI L
Sbjct  426  PFGGGAHRCIGMKFGMLEVKTILHYLLRTYRLEL-KPGYDVHWDTSSLPFPTDGLPITL  483


>gi|229491086|ref|ZP_04384916.1| cytochrome P450 monooxygenase [Rhodococcus erythropolis SK121]
 gi|229322006|gb|EEN87797.1| cytochrome P450 monooxygenase [Rhodococcus erythropolis SK121]
Length=497

 Score =  431 bits (1109),  Expect = 1e-118, Method: Compositional matrix adjust.
 Identities = 232/492 (48%), Positives = 308/492 (63%), Gaps = 12/492 (2%)

Query  4    IHPPAYLLDQAKRRFTPSFNNFPGMSLVEHMLLNT--KFPEKKLAEPPPGSGLKPVVGDA  61
            IH P   L + + R + S    P  S V+  LL    ++P ++LA PP GSGLKPV+G A
Sbjct  15   IHLP---LAKGRERLS-SVLMVPLPSRVDAALLGASDRWPVRELAPPPAGSGLKPVLGTA  70

Query  62   GLPILGHMIEMLRGGPDYLMFLYKTKGPVVFGDSAVLPGVAALGPDAAQVIYSNRNKDYS  121
            G+P+LGH ++ +R G ++    Y+  GPV +  +     VA  GPDA Q + + + K +S
Sbjct  71   GMPLLGHTLDYIRFGSNFSRARYQRLGPVSWMGAFGTKIVAVAGPDAIQEVLTTKAKSFS  130

Query  122  QQGWVPVIGPFFHRGLMLLDFEEHMFHRRIMQEAFVRSRLAGYLEQMDRVVSRVVADDWV  181
            Q GW  +I  FFHRGLML+ F+EH  HRRIMQEAF R RLAGY++Q+   +   +   W 
Sbjct  131  QDGWTYLIDAFFHRGLMLMSFDEHRMHRRIMQEAFTRDRLAGYVDQLGPTLEASIPG-WT  189

Query  182  VNDARFLVYPAMKALTLDIASMVFMGHEPGTDHELVTKVNKAFTITTRAGNAVIRTSVPP  241
               +   +YP +KALTLD+A+ VFM    G+  E    +N AF  T RA +++IR  +P 
Sbjct  190  AGQSTTRIYPLLKALTLDVATKVFMAGRGGS--EDTDAINDAFVATVRAASSIIRFPLPG  247

Query  242  FTWWRGLRARELLENYFTARVKERREASGNDLLTVLCQTEDDDGNRFSDADIVNHMIFLM  301
              W  G+R R LLE+YFT  +   R   G DL   LC     DG  F+D D+V+HMIFLM
Sbjct  248  TRWRAGVRGRALLEDYFTRHLPAARSGQGGDLFAGLCHARTADGEAFTDEDVVSHMIFLM  307

Query  302  MAAHDTSTSTATTMAYQLAAHPEWQQRCRDESDRHGDGPLDIESLEQLESLDLVMNESIR  361
            MAAHDTST T T  AY LA HP WQ+R R ESDR G    DI+ L+ LE+LDLV+ E++R
Sbjct  308  MAAHDTSTITTTAAAYFLAKHPAWQERARAESDRLGGRRPDIDDLDSLETLDLVIKETLR  367

Query  362  LVTPVQWAMRQTVRDTELLGYYLPKGTNVIAYPGMNHRLPEIWTDPLTFDPERFTEPRNE  421
            LV PV   MR+TV D ++ G+++P  T V   P +NH     WTDP TFDP+RF+EPR E
Sbjct  368  LVAPVPIVMRKTVEDVDIAGHHIPADTLVAVAPSVNHFDESCWTDPDTFDPDRFSEPRRE  427

Query  422  HKRHRYAFTPFGGGVHKCIGMVFDQLEIKTILHRLLRRYRLELSRPD-YQPRWDYSAMPI  480
             + HR  + PFGGGVHKCIG+ F  LE+K ILH +LR Y   +  PD Y+ RWD +++PI
Sbjct  428  DQNHRLGWIPFGGGVHKCIGLHFGTLEVKAILHHMLRTYTWTV--PDQYEARWDNTSLPI  485

Query  481  PMDGMPIVLRPR  492
            P+DG+PI L  R
Sbjct  486  PVDGLPITLERR  497


>gi|269127924|ref|YP_003301294.1| cytochrome P450 [Thermomonospora curvata DSM 43183]
 gi|268312882|gb|ACY99256.1| cytochrome P450 [Thermomonospora curvata DSM 43183]
Length=448

 Score =  422 bits (1084),  Expect = 1e-115, Method: Compositional matrix adjust.
 Identities = 219/448 (49%), Positives = 292/448 (66%), Gaps = 6/448 (1%)

Query  43   KKLAEPPPGSGLKPVVGDAGLPILGHMIEMLRGGPDYLMFLYKTKGPVVFGDSAVLPGVA  102
            K LA PPPGS LKPV+GD GLP++G+ ++ +R         Y   GPV +G +  L  V 
Sbjct  3    KVLAPPPPGSDLKPVLGDPGLPLIGNTLQTMRDPFGMARNRYLRFGPVTWGWTLGLRTVM  62

Query  103  ALGPDAAQVIYSNRNKDYSQQ-GWVPVIGPFFHRGLMLLDFEEHMFHRRIMQEAFVRSRL  161
              GP+ A+ I  N++K ++    W   IGPFF RG+MLLDFEEH+ HRRIMQ+AF R ++
Sbjct  63   VQGPEGAEAILVNKDKAFANGPAWTYYIGPFFRRGIMLLDFEEHLHHRRIMQQAFTRPKM  122

Query  162  AGYLEQMDRVVSRVVADDWVVNDARFLVYPAMKALTLDIASMVFMGHEPGTDHELVTKVN  221
              YLE M   ++R +   W   D  F  Y  +K L LD+A  VF+G +   +   + ++N
Sbjct  123  RSYLEIMTPGITRGI-KAWPTGDG-FQFYKRIKQLMLDLAIDVFVGVD--LEQAEIDRLN  178

Query  222  KAFTITTRAGNAVIRTSVPPFTWWRGLRARELLENYFTARVKERREASGNDLLTVLCQTE  281
             AF    RAG A+IRTSVP   W +GL+AR+ LE +F   +  +R   G+DL   LCQ E
Sbjct  179  GAFIDAVRAGTAIIRTSVPGLRWHKGLQARKELEAFFYRHLPAKRRDGGDDLFAALCQAE  238

Query  282  DDDGNRFSDADIVNHMIFLMMAAHDTSTSTATTMAYQLAAHPEWQQRCRDESDRHGDGPL  341
             +DG+RF+D D+VNHMIF +MAAHDTST T TTMAY LA HPEWQ+R R+ES   G   L
Sbjct  239  TEDGHRFTDEDVVNHMIFALMAAHDTSTITMTTMAYYLAKHPEWQERVREESQALGKPTL  298

Query  342  DIESLEQLESLDLVMNESIRLVTPVQWAMRQTVRDTELLGYYLPKGTNVIAYPGMNHRLP  401
            D + +++L SLDLVM E++RLV PV    R+ V+DT +LGY++PKGT V+     NHR+P
Sbjct  299  DFDDIDKLVSLDLVMKEALRLVPPVPALPRRAVKDTSILGYHIPKGTTVVVAALTNHRMP  358

Query  402  EIWTDPLTFDPERFTEPRNEHKRHRYAFTPFGGGVHKCIGMVFDQLEIKTILHRLLRRYR  461
            EIW DP  FDPERF E R E K HRYA+ PFGGG HKCIGM F  ++IK++LH++L  YR
Sbjct  359  EIWKDPERFDPERFAEHRREDKVHRYAWAPFGGGAHKCIGMHFAGVQIKSVLHQVLLNYR  418

Query  462  LELSRPDYQPRWDYSAMPIPMDGMPIVL  489
              + R  Y+   D +++P P DG+P+ L
Sbjct  419  WSVPR-GYEWPLDTTSLPSPKDGLPVRL  445


>gi|325001074|ref|ZP_08122186.1| cytochrome P450 [Pseudonocardia sp. P1]
Length=486

 Score =  417 bits (1071),  Expect = 3e-114, Method: Compositional matrix adjust.
 Identities = 210/435 (49%), Positives = 281/435 (65%), Gaps = 6/435 (1%)

Query  57   VVGDAGLPILGHMIEMLRGGPDYLMFLYKTKGPVVFGDSAVLPGVAALGPDAAQVIYSNR  116
            V+GD GLP LG  +E +R G D+    ++  GPV +        V   GP+A   + +N 
Sbjct  56   VLGDQGLPGLGRTLEYIRFGSDFTRARFERFGPVSWTGFLGERVVQVAGPEATHAVLTNA  115

Query  117  NKDYSQQGWVPVIGPFFHRGLMLLDFEEHMFHRRIMQEAFVRSRLAGYLEQMDRVVSRVV  176
            +K +SQ+GW  +I  FFHRGLMLLDF+EH FHRR+MQEAF   RL GY ++    V   V
Sbjct  116  DKAFSQEGWRFLIDNFFHRGLMLLDFDEHRFHRRVMQEAFTAERLQGYTDETVACVRETV  175

Query  177  ADDWVVNDARFLVYPAMKALTLDIASMVFMGHEPGTDHELVTKVNKAFTITTRAGNAVIR  236
               W   DA   +YPA+K+LTLD+A+ VFM   PG + E   +VNKAF    RA +++++
Sbjct  176  PT-WR-QDAPMRLYPALKSLTLDVATRVFMDDRPGPEAE---EVNKAFVDCVRAASSIVK  230

Query  237  TSVPPFTWWRGLRARELLENYFTARVKERREASGNDLLTVLCQTEDDDGNRFSDADIVNH  296
              VP   W  GLR R +LE YF A +  +R + G DL + LCQ    DG  FSD D+VNH
Sbjct  231  WDVPGTRWHAGLRGRRVLERYFRANLAAKRTSDGADLFSALCQARTPDGETFSDDDVVNH  290

Query  297  MIFLMMAAHDTSTSTATTMAYQLAAHPEWQQRCRDESDRHGDGPLDIESLEQLESLDLVM  356
            MIFLMMAAHDTST T++ +AY L A+PEWQ+R R ES   GD P D  +LE L++L+  +
Sbjct  291  MIFLMMAAHDTSTITSSAVAYYLGANPEWQERARAESLALGDTPPDRAALESLDTLNRAI  350

Query  357  NESIRLVTPVQWAMRQTVRDTELLGYYLPKGTNVIAYPGMNHRLPEIWTDPLTFDPERFT  416
             ES+RLV PV   MR+TV  T + G+Y+P  + V+    +NH  P  W++P TFDP+RF 
Sbjct  351  KESLRLVAPVPVVMRRTVAATAVCGHYVPANSLVMVAGAVNHFDPACWSEPDTFDPDRFA  410

Query  417  EPRNEHKRHRYAFTPFGGGVHKCIGMVFDQLEIKTILHRLLRRYRLELSRPDYQPRWDYS  476
            EPR E K HR A+ PFGGGVHKCIGM+F  LE+  I+H +LR +R  +  P Y+PRWD +
Sbjct  411  EPRREDKSHRDAWIPFGGGVHKCIGMIFGSLEVTAIMHEMLRAHRWSID-PGYRPRWDNT  469

Query  477  AMPIPMDGMPIVLRP  491
            ++P+P DG+P+ LRP
Sbjct  470  SLPVPADGLPLRLRP  484


>gi|326385246|ref|ZP_08206910.1| cytochrome P450 [Gordonia neofelifaecis NRRL B-59395]
 gi|326196030|gb|EGD53240.1| cytochrome P450 [Gordonia neofelifaecis NRRL B-59395]
Length=486

 Score =  413 bits (1061),  Expect = 4e-113, Method: Compositional matrix adjust.
 Identities = 220/484 (46%), Positives = 302/484 (63%), Gaps = 8/484 (1%)

Query  11   LDQAKRRFTPSF-NNFPGMSLVEHMLLNTKFPEKKLAEPPPGSGLKPVVGDAGLPILGHM  69
            L + + R +  F    P  +    + ++ ++P ++LA PP GSGL+PV G AG+P+LGH 
Sbjct  9    LAKGRERLSSVFLAPLPSRADATLLGVSDQWPVRELAPPPAGSGLEPVRGTAGMPLLGHT  68

Query  70   IEMLRGGPDYLMFLYKTKGPVVFGDSAVLPGVAALGPDAAQVIYSNRNKDYSQQGWVPVI  129
            ++ +R G ++    Y+  GPV +  +     V   G DA Q   + + K +SQ GW  +I
Sbjct  69   LDYIRFGSNFTRARYQRFGPVWWMGAFGTRIVMVAGADATQEALTTKAKSFSQDGWTYLI  128

Query  130  GPFFHRGLMLLDFEEHMFHRRIMQEAFVRSRLAGYLEQMDRVVSRVVADDWVVNDARFLV  189
              FFHRGLML+ F+EH  HRRIMQEAF R RLAGY++Q+   +   +   W    +   +
Sbjct  129  DAFFHRGLMLMSFDEHRMHRRIMQEAFTRDRLAGYVDQLGPTLETSIRR-WTAGRST-RI  186

Query  190  YPAMKALTLDIASMVFMGHEPGTDHELVTKVNKAFTITTRAGNAVIRTSVPPFTWWRGLR  249
            YP +KALTLD+A+ VFM    G+  E    +N AF  T RA +++IR  +P   W  G+ 
Sbjct  187  YPLLKALTLDVATEVFMAGRGGS--EDTDAINDAFVATVRAASSIIRFPLPGTRWRAGVH  244

Query  250  ARELLENYFTARVKERREASGNDLLTVLCQTEDDDGNRFSDADIVNHMIFLMMAAHDTST  309
             R LLE+YFT  +   R A G+DL   LC     DG  F+D D+VNHMIFLMMAAHDTST
Sbjct  245  GRTLLEDYFTRHLPTARSAQGDDLFAGLCHARTADGEAFTDEDVVNHMIFLMMAAHDTST  304

Query  310  STATTMAYQLAAHPEWQQRCRDESDRHGDGPLDIESLEQLESLDLVMNESIRLVTPVQWA  369
             T T  AY LA HP WQ+R R ESDR G+   DI+ L+ + +LDLV+ E++RLV PV   
Sbjct  305  ITTTAAAYFLAKHPAWQERARAESDRLGERRPDIDDLDSMATLDLVIKETLRLVAPVPIV  364

Query  370  MRQTVRDTELLGYYLPKGTNVIAYPGMNHRLPEIWTDPLTFDPERFTEPRNEHKRHRYAF  429
            MR+T+ + E+ G ++P  T V   P +NH     WT+P TFDP+RF+EPR+E + HR+ +
Sbjct  365  MRKTIENVEIAGRHIPADTLVAVAPAVNHFDESCWTEPDTFDPDRFSEPRHEDQNHRFGW  424

Query  430  TPFGGGVHKCIGMVFDQLEIKTILHRLLRRYRLELSRPD-YQPRWDYSAMPIPMDGMPIV  488
             PFGGGVHKCIG+ F  LE+K ILH +LR Y    S PD Y+ RWD +++PIP+DG+PI 
Sbjct  425  IPFGGGVHKCIGLHFGTLEVKAILHHMLRTY--TWSVPDQYEVRWDNTSLPIPVDGLPIT  482

Query  489  LRPR  492
            L  R
Sbjct  483  LERR  486


>gi|226364670|ref|YP_002782452.1| cytochrome P450 [Rhodococcus opacus B4]
 gi|226243159|dbj|BAH53507.1| putative cytochrome P450 [Rhodococcus opacus B4]
Length=464

 Score =  410 bits (1054),  Expect = 2e-112, Method: Compositional matrix adjust.
 Identities = 213/451 (48%), Positives = 277/451 (62%), Gaps = 4/451 (0%)

Query  43   KKLAEPPPGSGLKPVVGDAGLPILGHMIEMLRGGPDYLMFLYKTKGPVVFGDSAVLPGVA  102
            K LA PP  S L P+ G+AG P++GH +E  R     L   +   GPV +   A    V 
Sbjct  15   KVLAAPPQESTLSPISGNAGFPVIGHSLEYFRDPMGLLQSRWDRYGPVSWLSMAGKRWVT  74

Query  103  ALGPDAAQVIYSNRNKDY-SQQGWVPVIGPFFHRGLMLLDFEEHMFHRRIMQEAFVRSRL  161
             LGPD  Q +  NR++ + +  GW  +IGPFFHRGLMLLD +EH+ HRRIMQ+AF R RL
Sbjct  75   VLGPDGCQAVLQNRDRAFVNSDGWSVLIGPFFHRGLMLLDGDEHLAHRRIMQQAFTRDRL  134

Query  162  AGYLEQMDRVVSRVVADDWVVNDARFLVYPAMKALTLDIASMVFMGHEPGTDHELVTKVN  221
            + Y + +   V R + D W      F VYPA+K LTLD+A+ +FMG   G+ H  + +VN
Sbjct  135  SRYTDALHPAVERGL-DAWRPTPG-FAVYPALKELTLDLATSIFMGGAEGSTHREMAEVN  192

Query  222  KAFTITTRAGNAVIRTSVPPFTWWRGLRARELLENYFTARVKERREASGNDLLTVLCQTE  281
            KAF    +A  +V+R  +P   W RG+  R  LE +F   +  RR  +G DL + LC  E
Sbjct  193  KAFIDCVQAATSVVRYPLPGTRWKRGIDGRGRLEEFFRRYLPARRAGAGEDLFSALCHIE  252

Query  282  DDDGNRFSDADIVNHMIFLMMAAHDTSTSTATTMAYQLAAHPEWQQRCRDESDRHGDGPL  341
             +DG RFSD D++NHMIFL+MAAHDTST T +TM   L  HP+WQ RCR +S   G    
Sbjct  253  SEDGQRFSDDDVINHMIFLLMAAHDTSTITLSTMMQYLGQHPQWQDRCRRQSAALGTSTP  312

Query  342  DIESLEQLESLDLVMNESIRLVTPVQWAMRQTVRDTELLGYYLPKGTNVIAYPGMNHRLP  401
            D   LE+L  LDLVM E +RLV PV    R+ V+DTE+LG+Y+PKGT +       H +P
Sbjct  313  DYGELEELTDLDLVMKECLRLVPPVPVVARRAVQDTEVLGHYIPKGTYMSVVVHFTHHMP  372

Query  402  EIWTDPLTFDPERFTEPRNEHKRHRYAFTPFGGGVHKCIGMVFDQLEIKTILHRLLRRYR  461
            E W DP  FDPERF   R E K HRYA+ PFGGGVHKC+GM F   EIKT++H LL+R+ 
Sbjct  373  EYWPDPERFDPERFAPERREDKVHRYAWEPFGGGVHKCLGMHFAGAEIKTVMHHLLQRFD  432

Query  462  LELSRPDYQPRWDYSAMPIPMDGMPIVLRPR  492
              +S P Y    +Y+++P P DG P+ L  R
Sbjct  433  WRVS-PGYVAPLNYTSLPFPSDGQPVDLYHR  462


>gi|294811192|ref|ZP_06769835.1| Cytochrome P450 [Streptomyces clavuligerus ATCC 27064]
 gi|326439693|ref|ZP_08214427.1| cytochrome P450 [Streptomyces clavuligerus ATCC 27064]
 gi|294323791|gb|EFG05434.1| Cytochrome P450 [Streptomyces clavuligerus ATCC 27064]
Length=457

 Score =  405 bits (1040),  Expect = 1e-110, Method: Compositional matrix adjust.
 Identities = 216/451 (48%), Positives = 278/451 (62%), Gaps = 7/451 (1%)

Query  42   EKKLAEPPPGSGLKPVVGDAGLPILGHMIEMLRGGPDYLMFLYKTKGPVVFGDSAVLPGV  101
               LA  P GS L PV+GD GLP +G+ +  +     +    Y   GPV +G+    P V
Sbjct  7    SSSLAPAPSGSALAPVMGDPGLPYIGYALHTMWNPIRHFRRRYDQYGPVSWGNFLGRPIV  66

Query  102  AALGPDAAQVIYSNRNKDY-SQQGWVPVIGPFFHRGLMLLDFEEHMFHRRIMQEAFVRSR  160
            +  GP+AAQV+  NR K + S   W   IGPFF RG+MLLD +EH+ HRRIMQ+AF R R
Sbjct  67   SVQGPEAAQVVLGNREKAFASGPAWDYFIGPFFERGIMLLDSDEHLRHRRIMQQAFTRER  126

Query  161  LAGYLEQMDRVVSRVVADDWVVNDARFLVYPAMKALTLDIASMVFMGHEPGTDHELVTKV  220
            LAGYLE +D+   R + D W     R  + P  + LTLD+A  VF+  +   D     +V
Sbjct  127  LAGYLEYIDQSARRGI-DAW--RPGRRTLLPLFRRLTLDMALDVFLALD--LDRAGSHRV  181

Query  221  NKAFTITTRAGNAVIRTSVPPFTWWRGLRARELLENYFTARVKERREASGNDLLTVLCQT  280
             +AF    RAG A++R  VP   W RGL+AR  L ++ T  +  +R+  G+DL  VLC  
Sbjct  182  ERAFEDAVRAGLALVRFPVPGLRWSRGLKARRYLVDFLTGHIPAKRDRGGDDLFAVLCGA  241

Query  281  EDDDGNRFSDADIVNHMIFLMMAAHDTSTSTATTMAYQLAAHPEWQQRCRDESDRHGDGP  340
              +DG RFSD D+VNHMIF++MAAHDTST   TTMAY LA HPEWQ+RCRD S   GDGP
Sbjct  242  RSEDGERFSDTDVVNHMIFVLMAAHDTSTIALTTMAYYLARHPEWQERCRDRSLALGDGP  301

Query  341  LDIESLEQLESLDLVMNESIRLVTPVQWAMRQTVRDTELLGYYLPKGTNVIAYPGMNHRL  400
            +D  +L+ L  LDLV+ ES+RL  PV    R  VRDTE+LG+++P GT V      NHRL
Sbjct  302  VDSAALDALTELDLVLRESLRLCPPVPLLPRIAVRDTEVLGHHIPAGTFVGVTAFSNHRL  361

Query  401  PEIWTDPLTFDPERFTEPRNEHKRHRYAFTPFGGGVHKCIGMVFDQLEIKTILHRLLRRY  460
            PE W DP  FDPERF   R     H Y++ PFGGGVHKCIGM F  L+IK ++H++LR +
Sbjct  362  PEHWPDPERFDPERFAVARRTEITHPYSWFPFGGGVHKCIGMHFANLQIKAVMHQMLRTH  421

Query  461  RLELSRPDYQPRWDYSAMPIPMDGMPIVLRP  491
               +    Y  R D S +P+P DG+P+ LRP
Sbjct  422  AWSVPE-GYTWRLDMSTLPVPRDGLPVTLRP  451


>gi|262202429|ref|YP_003273637.1| cytochrome P450 [Gordonia bronchialis DSM 43247]
 gi|262085776|gb|ACY21744.1| cytochrome P450 [Gordonia bronchialis DSM 43247]
Length=480

 Score =  400 bits (1028),  Expect = 3e-109, Method: Compositional matrix adjust.
 Identities = 210/452 (47%), Positives = 281/452 (63%), Gaps = 8/452 (1%)

Query  43   KKLAEPPPGSGLKPVVGDAGLPILGHMIEMLRGGPDYLMFLYKTKGPVVFGDSAVLPGVA  102
            + LAEPP GSGLKPV+GD GLP+LG+ +E L       M  Y+  GPV +  S  +  V 
Sbjct  35   RPLAEPPAGSGLKPVLGDPGLPLLGNTLEALADPLRSAMQRYERYGPVTWSGSLGMNIVT  94

Query  103  ALGPDAAQVIYSNRNKDYS-QQGWVPVIGPFFHRGLMLLDFEEHMFHRRIMQEAFVRSRL  161
             +GP+A +  + NR K +S +QGW P+IGPFF RG+ML+DFEEHM HRRI+Q+AF  +RL
Sbjct  95   LVGPEAIECAWMNREKAFSSEQGWEPMIGPFFRRGVMLMDFEEHMHHRRILQQAFTTNRL  154

Query  162  AGYLEQMDRVVSRVVADDWVVNDARFLVYPAMKALTLDIASMVFMGHEPGTDHELVTKVN  221
             GYL  M   + + +A+ W V +  F +Y   K LTL +A+ VF+G     +     ++ 
Sbjct  155  KGYLGMMTPHIEKTLAN-WPVGEG-FPMYSRTKDLTLSLATEVFVG--ASLNEAEAHRLE  210

Query  222  KAFTITTRAGNAVIRTSVPPFTWWRGLRARELLENYFTARVKERREASGNDLLTVLCQTE  281
             AF    R G A+IR  V   TW RGLR RE L+ YF + +  RR   G+DL +VLC +E
Sbjct  211  TAFEAAVRGGQAIIRADVKFGTWARGLRGREALQRYFRSEIAARRAGDGDDLFSVLCHSE  270

Query  282  DDDGNRFSDADIVNHMIFLMMAAHDTSTSTATTMAYQLAAHPEWQQRCRDESDRHGDGPL  341
              +G+ F+D D+VNHMIF+MMAAHDTST   + + Y L  HPEWQ R R ES   G   L
Sbjct  271  SPEGDTFTDEDVVNHMIFVMMAAHDTSTIALSMLTYFLGRHPEWQDRLRAESLALGKDTL  330

Query  342  DIESLEQLESLDLVMNESIRLVTPVQWAMRQTVRDTELLGYYLPKGTNVIAYPGMNHRLP  401
            D E ++ L SLDL   E+IR+  PV    R+ VRDT++LG+Y+P GT V  +P       
Sbjct  331  DYEDIDALTSLDLAFKETIRINAPVGMLFRKAVRDTDILGHYVPAGTLVAIHPWATMLRE  390

Query  402  EIWTDPLTFDPERFTEPRNEHKRHRYAFTPFGGGVHKCIGMVFDQLEIKTILHRLLRRYR  461
            E W +P  +DPERF+  R E K HR+A+ PFGGG HKCIG+ F  +E+K I+H++L+R+ 
Sbjct  391  EWWPNPTHWDPERFSPERREDKVHRFAWAPFGGGAHKCIGLYFGGMEVKAIMHQMLQRF-  449

Query  462  LELSRP-DYQPRWDYSAMPIPMDGMPIVLRPR  492
             E S P  Y P  +Y   P P DG+PI  R R
Sbjct  450  -EWSVPAGYFPELEYGTGPTPADGLPIDFRRR  480


>gi|111022177|ref|YP_705149.1| cytochrome P450 [Rhodococcus jostii RHA1]
 gi|110821707|gb|ABG96991.1| cytochrome P450 CYP136 [Rhodococcus jostii RHA1]
Length=463

 Score =  400 bits (1027),  Expect = 3e-109, Method: Compositional matrix adjust.
 Identities = 206/451 (46%), Positives = 277/451 (62%), Gaps = 4/451 (0%)

Query  43   KKLAEPPPGSGLKPVVGDAGLPILGHMIEMLRGGPDYLMFLYKTKGPVVFGDSAVLPGVA  102
            K LA PPP S L+P+ G+AG P++GH ++  R     L   +   GPV +   A    V 
Sbjct  9    KVLAAPPPQSTLQPISGNAGFPVIGHSLDYFRDPMGLLQSRWDRYGPVSWLSMAGKRWVT  68

Query  103  ALGPDAAQVIYSNRNKDY-SQQGWVPVIGPFFHRGLMLLDFEEHMFHRRIMQEAFVRSRL  161
             LGPD  Q +  N+++ + +  GW  +IGPFFHRGLMLLD +EH+ HRRIMQ+AF R RL
Sbjct  69   VLGPDGCQTVLQNKDRAFVNSDGWSVLIGPFFHRGLMLLDGDEHLAHRRIMQQAFTRDRL  128

Query  162  AGYLEQMDRVVSRVVADDWVVNDARFLVYPAMKALTLDIASMVFMGHEPGTDHELVTKVN  221
            + Y E +   V + + D W    A F  YPA+K LTLD+A+ +FMG   G+    + ++N
Sbjct  129  SRYTEALHPAVEKGL-DGWQPT-AGFAAYPALKELTLDLATSIFMGGAEGSTPREMAEIN  186

Query  222  KAFTITTRAGNAVIRTSVPPFTWWRGLRARELLENYFTARVKERREASGNDLLTVLCQTE  281
            +AF    +A  +VIR  +    W RG+  R  LE +F   +  RR  +G DL + LC  E
Sbjct  187  RAFIDCVQAATSVIRYPLLGTRWKRGIDGRARLEEFFRRYLPARRAGAGEDLFSALCHIE  246

Query  282  DDDGNRFSDADIVNHMIFLMMAAHDTSTSTATTMAYQLAAHPEWQQRCRDESDRHGDGPL  341
             ++G RFSD D+VNHMIFL+MAAHDTST T +TM   L  HP+WQ+RCR +S   G    
Sbjct  247  SEEGQRFSDDDVVNHMIFLLMAAHDTSTITLSTMMQYLGQHPDWQERCRRQSAALGTSTP  306

Query  342  DIESLEQLESLDLVMNESIRLVTPVQWAMRQTVRDTELLGYYLPKGTNVIAYPGMNHRLP  401
              + L++L  LDLVM E +RLV PV    R+ V DTE+LG+Y+P+GT +       H +P
Sbjct  307  TYDQLDELTDLDLVMKECLRLVPPVPVVARRAVEDTEVLGHYIPRGTYMSVVVHFTHHMP  366

Query  402  EIWTDPLTFDPERFTEPRNEHKRHRYAFTPFGGGVHKCIGMVFDQLEIKTILHRLLRRYR  461
            E W DP  FDPERF   R E K HR+A+ PFGGGVHKC+GM F   EIKT++H LLRR+ 
Sbjct  367  EYWPDPERFDPERFAPERREDKVHRFAWEPFGGGVHKCLGMHFAGAEIKTVMHHLLRRFH  426

Query  462  LELSRPDYQPRWDYSAMPIPMDGMPIVLRPR  492
              +S P Y    +Y+++P P DG P+ L  R
Sbjct  427  WHVS-PGYVAPLNYTSLPFPSDGQPVDLYHR  456


>gi|183983133|ref|YP_001851424.1| cytochrome P450 136B2 Cyp136B2 [Mycobacterium marinum M]
 gi|183176459|gb|ACC41569.1| cytochrome P450 136B2 Cyp136B2 [Mycobacterium marinum M]
Length=485

 Score =  399 bits (1026),  Expect = 5e-109, Method: Compositional matrix adjust.
 Identities = 207/450 (46%), Positives = 284/450 (64%), Gaps = 6/450 (1%)

Query  43   KKLAEPPPGSGLKPVVGDAGLPILGHMIEMLRGGPDYLMFLYKTKGPVVFGDSAVLPGVA  102
            ++LA  P GSGL+ V+GDAGLP+LGH ++ +R G ++    Y+  G V +  +     V 
Sbjct  42   RELAPAPAGSGLRAVLGDAGLPLLGHTVDYIRFGSEFSRERYERLGSVSWMGAFGTKMVV  101

Query  103  ALGPDAAQVIYSNRNKDYSQQGWVPVIGPFFHRGLMLLDFEEHMFHRRIMQEAFVRSRLA  162
              GPDA +  +++  K +SQ GW  +I  FFHRGLML+ F+EH+ HRRIMQEAF R RL 
Sbjct  102  IAGPDATREAFTSEAKAFSQDGWSFLIDAFFHRGLMLMSFDEHLMHRRIMQEAFTRPRLT  161

Query  163  GYLEQMDRVVSRVVADDWVVNDARFLVYPAMKALTLDIASMVFMGHEPGTDHELVTKVNK  222
            GY+ Q+   V R     W    +   +YP +K LTLDIA+ VFMG   G   +    VN+
Sbjct  162  GYVGQVAPCV-RAAVPAWPTGPS-VRIYPLLKNLTLDIATDVFMG---GRGKDESAAVNE  216

Query  223  AFTITTRAGNAVIRTSVPPFTWWRGLRARELLENYFTARVKERREASGNDLLTVLCQTED  282
            AF  T RA ++ +R  +P   +  G+  R +LE+YF+  +   R    +DL   LCQ   
Sbjct  217  AFVSTVRAASSFVRVPLPGTRFRAGVHGRRVLEDYFSRHLPAARAGETDDLFAALCQATT  276

Query  283  DDGNRFSDADIVNHMIFLMMAAHDTSTSTATTMAYQLAAHPEWQQRCRDESDRHGDGPLD  342
            +DG RFSD D++NHMIFLMMAAHDTST T T + Y LA HPEWQ++   E+   G    D
Sbjct  277  EDGERFSDEDVINHMIFLMMAAHDTSTITTTAVTYFLAKHPEWQEKAAAEARSFGHDSPD  336

Query  343  IESLEQLESLDLVMNESIRLVTPVQWAMRQTVRDTELLGYYLPKGTNVIAYPGMNHRLPE  402
            I+ LE++  LDL++ E++RL+ PV   MR+TVRD  + GY++P+ T     P +NH    
Sbjct  337  IDELERMTVLDLILKEALRLLAPVPLVMRKTVRDVAIDGYHIPRETLCAITPAVNHFDRR  396

Query  403  IWTDPLTFDPERFTEPRNEHKRHRYAFTPFGGGVHKCIGMVFDQLEIKTILHRLLRRYRL  462
            IW+DP  FDP RF EPR E ++HR+A+ PFGGG HKCIGM F  LE+K ILH++LR Y  
Sbjct  397  IWSDPDRFDPSRFDEPRREDQQHRFAWVPFGGGAHKCIGMQFGTLEVKAILHQMLRTYTW  456

Query  463  ELSRPDYQPRWDYSAMPIPMDGMPIVLRPR  492
             +   DY  RWD +++PIP+DG+P+ LR R
Sbjct  457  TVPN-DYHVRWDNTSLPIPVDGLPVTLRHR  485


>gi|343927897|ref|ZP_08767363.1| putative cytochrome P450 [Gordonia alkanivorans NBRC 16433]
 gi|343762120|dbj|GAA14289.1| putative cytochrome P450 [Gordonia alkanivorans NBRC 16433]
Length=464

 Score =  399 bits (1025),  Expect = 5e-109, Method: Compositional matrix adjust.
 Identities = 205/460 (45%), Positives = 288/460 (63%), Gaps = 8/460 (1%)

Query  36   LNTKFPEKK--LAEPPPGSGLKPVVGDAGLPILGHMIEMLRGGPDYLMFLYKTKGPVVFG  93
            L++ +P K+  LAEPP GSGLKPV+GD G+P LG+ ++ L       M  ++  G V + 
Sbjct  8    LSSMYPSKERPLAEPPAGSGLKPVMGDPGIPYLGNTLQALADPLQSAMDRFERYGQVSWS  67

Query  94   DSAVLPGVAALGPDAAQVIYSNRNKDYSQQ-GWVPVIGPFFHRGLMLLDFEEHMFHRRIM  152
             +  +  V  +GPDA + ++ NRNK +S + GW P+IGPFF RG+ML+DF+EHM HRRIM
Sbjct  68   GALGMNMVTLVGPDAIEAVWMNRNKAFSSELGWEPMIGPFFRRGVMLMDFDEHMQHRRIM  127

Query  153  QEAFVRSRLAGYLEQMDRVVSRVVADDWVVNDARFLVYPAMKALTLDIASMVFMGHEPGT  212
            Q+AF R RL GYL+ M   + + +A+ W V    F +Y   K LTL +A+ VFMG     
Sbjct  128  QQAFSRPRLNGYLDIMTPHIEKTLAN-WQVGKG-FHMYSNTKDLTLSLATEVFMGAH--V  183

Query  213  DHELVTKVNKAFTITTRAGNAVIRTSVPPFTWWRGLRARELLENYFTARVKERREASGND  272
                  ++ KAF    R G A++R  V  +TW +GLR RE+L+ YF + +  RR +  +D
Sbjct  184  SEAEAHRLEKAFEAAVRGGQAMVRKDVGNWTWAQGLRGREVLQEYFRSEIPLRRGSDADD  243

Query  273  LLTVLCQTEDDDGNRFSDADIVNHMIFLMMAAHDTSTSTATTMAYQLAAHPEWQQRCRDE  332
            L TVLC +E D+G  F+D DIVNHMIF+MMAAHDTST   + + Y L  HPEWQQR R+E
Sbjct  244  LFTVLCNSESDEGETFTDEDIVNHMIFVMMAAHDTSTIALSMLTYFLGRHPEWQQRLREE  303

Query  333  SDRHGDGPLDIESLEQLESLDLVMNESIRLVTPVQWAMRQTVRDTELLGYYLPKGTNVIA  392
            S       +D + +++L S++L   E++RL  PV    R  + DTE+ G+Y+PKGT +  
Sbjct  304  SLALNKPTIDYDDVDKLPSMELAFKETLRLNAPVGMLFRMAIEDTEICGHYIPKGTLLAI  363

Query  393  YPGMNHRLPEIWTDPLTFDPERFTEPRNEHKRHRYAFTPFGGGVHKCIGMVFDQLEIKTI  452
            +P       E W +P  FDPERF+  R E K HR+A+ PFGGG HKCIG+ F  +E+K+I
Sbjct  364  HPWATMLRKEWWPNPTHFDPERFSAERREDKVHRFAWAPFGGGAHKCIGLYFGGMEVKSI  423

Query  453  LHRLLRRYRLELSRPDYQPRWDYSAMPIPMDGMPIVLRPR  492
            LH++L+R+   +    Y+P   Y   P P DG+PI +R R
Sbjct  424  LHQMLQRFEWTVP-AGYKPELTYGTGPTPADGLPIDIRHR  462


>gi|108800154|ref|YP_640351.1| cytochrome P450 [Mycobacterium sp. MCS]
 gi|119869282|ref|YP_939234.1| cytochrome P450 [Mycobacterium sp. KMS]
 gi|126435779|ref|YP_001071470.1| cytochrome P450 [Mycobacterium sp. JLS]
 gi|108770573|gb|ABG09295.1| cytochrome P450 [Mycobacterium sp. MCS]
 gi|119695371|gb|ABL92444.1| cytochrome P450 [Mycobacterium sp. KMS]
 gi|126235579|gb|ABN98979.1| cytochrome P450 [Mycobacterium sp. JLS]
Length=485

 Score =  397 bits (1019),  Expect = 3e-108, Method: Compositional matrix adjust.
 Identities = 211/453 (47%), Positives = 286/453 (64%), Gaps = 6/453 (1%)

Query  40   FPEKKLAEPPPGSGLKPVVGDAGLPILGHMIEMLRGGPDYLMFLYKTKGPVVFGDSAVLP  99
            +P ++LA  P GSGLK V GDAGLP +GH ++ +R G D+    Y   G V +  +    
Sbjct  39   WPVRELAPAPAGSGLKAVRGDAGLPFVGHTLDYIRFGSDFSRERYDRLGSVSWMGAFGTK  98

Query  100  GVAALGPDAAQVIYSNRNKDYSQQGWVPVIGPFFHRGLMLLDFEEHMFHRRIMQEAFVRS  159
             V   GPDA +  +++  K +SQ GW  +I  FFHRGLML+ F+EH+ HRRIMQEAF R 
Sbjct  99   MVVIAGPDATREAFTSEAKAFSQDGWSFLIDAFFHRGLMLMSFDEHLMHRRIMQEAFTRP  158

Query  160  RLAGYLEQMDRVVSRVVADDWVVNDARFLVYPAMKALTLDIASMVFMGHEPGTDHELVTK  219
            RL GY+EQ+   V R     W V  +   +YP +K LTLDIA+ VFMG   G   +    
Sbjct  159  RLTGYVEQVTPCV-RSAVPAWPVGPS-VRIYPLLKELTLDIATDVFMG---GRGKDESDA  213

Query  220  VNKAFTITTRAGNAVIRTSVPPFTWWRGLRARELLENYFTARVKERREASGNDLLTVLCQ  279
            VNKAF  T RA ++++R  +P   +  G++ R +LE+YF   +   R     DL   LCQ
Sbjct  214  VNKAFVATVRAASSLVRAPLPGTRFRAGVQGRRVLEDYFFRHLPAARAGETEDLFAALCQ  273

Query  280  TEDDDGNRFSDADIVNHMIFLMMAAHDTSTSTATTMAYQLAAHPEWQQRCRDESDRHGDG  339
               +DG RFSD D+VNHMIFLMMAAHDTST T T + Y LA +P+WQ+    E+   GDG
Sbjct  274  ATTEDGERFSDEDVVNHMIFLMMAAHDTSTITTTAVTYFLAKYPQWQEAAAAEAAAIGDG  333

Query  340  PLDIESLEQLESLDLVMNESIRLVTPVQWAMRQTVRDTELLGYYLPKGTNVIAYPGMNHR  399
              DIE+LE++  +DLV+ E++RL+ PV   MR+TVRD  + GY++P  T     P +NH 
Sbjct  334  LPDIEALEKMTVIDLVIKEALRLLAPVPLVMRKTVRDVAIDGYHIPSNTLCAITPAVNHF  393

Query  400  LPEIWTDPLTFDPERFTEPRNEHKRHRYAFTPFGGGVHKCIGMVFDQLEIKTILHRLLRR  459
               IW+DP  FDP RF EPR E + HR+A+ PFGGG HKCIGM F  LE+K ILHR+LR 
Sbjct  394  DRTIWSDPERFDPSRFDEPRREDQHHRFAWVPFGGGAHKCIGMQFGTLEVKAILHRMLRS  453

Query  460  YRLELSRPDYQPRWDYSAMPIPMDGMPIVLRPR  492
            +  ++   +Y  RWD +++PIP+DG+P+ ++ R
Sbjct  454  FTWKVPE-NYHVRWDNTSLPIPVDGLPLEMKRR  485


>gi|296165242|ref|ZP_06847789.1| P450 heme-thiolate protein [Mycobacterium parascrofulaceum ATCC 
BAA-614]
 gi|295899431|gb|EFG78890.1| P450 heme-thiolate protein [Mycobacterium parascrofulaceum ATCC 
BAA-614]
Length=485

 Score =  395 bits (1016),  Expect = 7e-108, Method: Compositional matrix adjust.
 Identities = 212/453 (47%), Positives = 284/453 (63%), Gaps = 6/453 (1%)

Query  40   FPEKKLAEPPPGSGLKPVVGDAGLPILGHMIEMLRGGPDYLMFLYKTKGPVVFGDSAVLP  99
            +P ++LA  P GSGLK V GDAGLP +GH ++ +R G D+    Y   G V +  +    
Sbjct  39   WPVRELAPAPAGSGLKAVRGDAGLPFVGHTLDYIRFGSDFSRERYDRLGSVSWMGAFGTK  98

Query  100  GVAALGPDAAQVIYSNRNKDYSQQGWVPVIGPFFHRGLMLLDFEEHMFHRRIMQEAFVRS  159
             V   GPDA +  +++  K +SQ GW  +I  FFHRGLML+ F+EH+ HRRIMQEAF R 
Sbjct  99   MVVIAGPDATREAFTSEAKAFSQDGWSFLIDAFFHRGLMLMSFDEHLMHRRIMQEAFTRP  158

Query  160  RLAGYLEQMDRVVSRVVADDWVVNDARFLVYPAMKALTLDIASMVFMGHEPGTDHELVTK  219
            RL GY+EQ+   V R     W V  +   +YP +K LTLDIA+ VFMG   G   +    
Sbjct  159  RLTGYVEQVTPCV-RSAVPAWPVGPS-VRIYPLLKELTLDIATDVFMG---GRGKDESDA  213

Query  220  VNKAFTITTRAGNAVIRTSVPPFTWWRGLRARELLENYFTARVKERREASGNDLLTVLCQ  279
            VNKAF  T RA ++++R  +P   +  G++ R +LE+YF   +   R     DL   LCQ
Sbjct  214  VNKAFVATVRAASSLVRAPLPGTRFRAGVQGRRVLEDYFFRHLPAARAGETEDLFAALCQ  273

Query  280  TEDDDGNRFSDADIVNHMIFLMMAAHDTSTSTATTMAYQLAAHPEWQQRCRDESDRHGDG  339
               +DG RFSD D+VNHMIFLMMAAHDTST T T + Y LA +P+WQ+    E+   GDG
Sbjct  274  ATTEDGERFSDEDVVNHMIFLMMAAHDTSTITTTAVTYFLAKYPQWQEAAAAEAAAIGDG  333

Query  340  PLDIESLEQLESLDLVMNESIRLVTPVQWAMRQTVRDTELLGYYLPKGTNVIAYPGMNHR  399
              DIE+LE++  +DLV+ E++RL+ PV   MR+TVRD  + GY++P  T     P +NH 
Sbjct  334  LPDIEALEKMTVIDLVIKEALRLLAPVPLVMRKTVRDVAIDGYHIPSNTLCAITPAVNHF  393

Query  400  LPEIWTDPLTFDPERFTEPRNEHKRHRYAFTPFGGGVHKCIGMVFDQLEIKTILHRLLRR  459
               IW+DP  FDP RF EPR E + HR+A+ PFGGG HKCIGM F  LE+K ILHR+LR 
Sbjct  394  DRTIWSDPGRFDPSRFDEPRREDQHHRFAWVPFGGGAHKCIGMQFGTLEVKAILHRMLRS  453

Query  460  YRLELSRPDYQPRWDYSAMPIPMDGMPIVLRPR  492
                +   +Y  RWD +++PIP+DG+P+ L+ R
Sbjct  454  LTWTVPE-NYHVRWDNTSLPIPVDGLPLQLKRR  485


>gi|23573434|gb|AAN38721.1| cytochrome p450 [Mycobacterium abscessus]
Length=498

 Score =  394 bits (1011),  Expect = 2e-107, Method: Compositional matrix adjust.
 Identities = 210/453 (47%), Positives = 284/453 (63%), Gaps = 6/453 (1%)

Query  40   FPEKKLAEPPPGSGLKPVVGDAGLPILGHMIEMLRGGPDYLMFLYKTKGPVVFGDSAVLP  99
            +P ++LA  P GSGLK V GDAGLP +GH ++ +R G D+    Y   G V +  +    
Sbjct  52   WPVRELAPAPAGSGLKAVRGDAGLPFVGHTLDYIRFGSDFSRERYDRLGSVSWMGAFGTK  111

Query  100  GVAALGPDAAQVIYSNRNKDYSQQGWVPVIGPFFHRGLMLLDFEEHMFHRRIMQEAFVRS  159
             V   GPDA +  +++  K +SQ GW  +I  FFHRGLML+ F+EH+ HRRIMQEAF R 
Sbjct  112  MVVIAGPDATREAFTSEAKAFSQDGWSFLIDAFFHRGLMLMSFDEHLMHRRIMQEAFTRP  171

Query  160  RLAGYLEQMDRVVSRVVADDWVVNDARFLVYPAMKALTLDIASMVFMGHEPGTDHELVTK  219
            RL GY+EQ+   V R     W V  +   +YP +K LTLDIA+ VFMG   G   +    
Sbjct  172  RLTGYVEQVTPCV-RSAVPAWPVGPS-VRIYPLLKELTLDIATDVFMG---GRGKDESDA  226

Query  220  VNKAFTITTRAGNAVIRTSVPPFTWWRGLRARELLENYFTARVKERREASGNDLLTVLCQ  279
            VNKAF  T RA ++++R  +P   +  G++ R +LE+YF   +   R     DL   LCQ
Sbjct  227  VNKAFVATVRAASSLVRAPLPGTRFRAGVQGRRVLEDYFFRHLPAARAGETEDLFAALCQ  286

Query  280  TEDDDGNRFSDADIVNHMIFLMMAAHDTSTSTATTMAYQLAAHPEWQQRCRDESDRHGDG  339
               +DG RFSD D+VNHMIFLMMAAHDTST T T + Y LA +P+WQ+    E+   GDG
Sbjct  287  ATTEDGERFSDEDVVNHMIFLMMAAHDTSTITTTAVTYFLAKYPQWQEAAAAEAAAIGDG  346

Query  340  PLDIESLEQLESLDLVMNESIRLVTPVQWAMRQTVRDTELLGYYLPKGTNVIAYPGMNHR  399
              DIE+LE++  +D V+ E++RL+ PV   MR+TVRD  + GY++P  T     P +NH 
Sbjct  347  LPDIEALEKMTVIDRVIKEALRLLAPVPLVMRKTVRDVAIDGYHIPSNTLCAITPAVNHF  406

Query  400  LPEIWTDPLTFDPERFTEPRNEHKRHRYAFTPFGGGVHKCIGMVFDQLEIKTILHRLLRR  459
               IW DP  FDP RF EPR E + HR+A+ PFGGG HKCIGM F  LE+K ILHR+LR 
Sbjct  407  DRTIWNDPERFDPSRFDEPRREDQHHRFAWVPFGGGAHKCIGMQFGTLEVKAILHRMLRS  466

Query  460  YRLELSRPDYQPRWDYSAMPIPMDGMPIVLRPR  492
            +  ++   +Y  RWD +++PIP+DG+P+ ++ R
Sbjct  467  FTWKVPE-NYHVRWDNTSLPIPVDGLPLEMKRR  498


>gi|169629164|ref|YP_001702813.1| cytochrome P450 [Mycobacterium abscessus ATCC 19977]
 gi|169241131|emb|CAM62159.1| Probable cytochrome P450 [Mycobacterium abscessus]
Length=485

 Score =  394 bits (1011),  Expect = 2e-107, Method: Compositional matrix adjust.
 Identities = 210/453 (47%), Positives = 284/453 (63%), Gaps = 6/453 (1%)

Query  40   FPEKKLAEPPPGSGLKPVVGDAGLPILGHMIEMLRGGPDYLMFLYKTKGPVVFGDSAVLP  99
            +P ++LA  P GSGLK V GDAGLP +GH ++ +R G D+    Y   G V +  +    
Sbjct  39   WPVRELAPAPAGSGLKAVRGDAGLPFVGHTLDYIRFGSDFSRERYDRLGSVSWMGAFGTK  98

Query  100  GVAALGPDAAQVIYSNRNKDYSQQGWVPVIGPFFHRGLMLLDFEEHMFHRRIMQEAFVRS  159
             V   GPDA +  +++  K +SQ GW  +I  FFHRGLML+ F+EH+ HRRIMQEAF R 
Sbjct  99   MVVIAGPDATREAFTSEAKAFSQDGWSFLIDAFFHRGLMLMSFDEHLMHRRIMQEAFTRP  158

Query  160  RLAGYLEQMDRVVSRVVADDWVVNDARFLVYPAMKALTLDIASMVFMGHEPGTDHELVTK  219
            RL GY+EQ+   V R     W V  +   +YP +K LTLDIA+ VFMG   G   +    
Sbjct  159  RLTGYVEQVTPCV-RSAVPAWPVGPS-VRIYPLLKELTLDIATDVFMG---GRGKDESDA  213

Query  220  VNKAFTITTRAGNAVIRTSVPPFTWWRGLRARELLENYFTARVKERREASGNDLLTVLCQ  279
            VNKAF  T RA ++++R  +P   +  G++ R +LE+YF   +   R     DL   LCQ
Sbjct  214  VNKAFVATVRAASSLVRAPLPGTRFRAGVQGRRVLEDYFFRHLPAARAGETEDLFAALCQ  273

Query  280  TEDDDGNRFSDADIVNHMIFLMMAAHDTSTSTATTMAYQLAAHPEWQQRCRDESDRHGDG  339
               +DG RFSD D+VNHMIFLMMAAHDTST T T + Y LA +P+WQ+    E+   GDG
Sbjct  274  ATTEDGERFSDEDVVNHMIFLMMAAHDTSTITTTAVTYFLAKYPQWQEAAAAEAAAIGDG  333

Query  340  PLDIESLEQLESLDLVMNESIRLVTPVQWAMRQTVRDTELLGYYLPKGTNVIAYPGMNHR  399
              DIE+LE++  +D V+ E++RL+ PV   MR+TVRD  + GY++P  T     P +NH 
Sbjct  334  LPDIEALEKMTVIDRVIKEALRLLAPVPLVMRKTVRDVAIDGYHIPSNTLCAITPAVNHF  393

Query  400  LPEIWTDPLTFDPERFTEPRNEHKRHRYAFTPFGGGVHKCIGMVFDQLEIKTILHRLLRR  459
               IW DP  FDP RF EPR E + HR+A+ PFGGG HKCIGM F  LE+K ILHR+LR 
Sbjct  394  DRTIWNDPERFDPSRFDEPRREDQHHRFAWVPFGGGAHKCIGMQFGTLEVKAILHRMLRS  453

Query  460  YRLELSRPDYQPRWDYSAMPIPMDGMPIVLRPR  492
            +  ++   +Y  RWD +++PIP+DG+P+ ++ R
Sbjct  454  FTWKVPE-NYHVRWDNTSLPIPVDGLPLEMKRR  485


>gi|326330071|ref|ZP_08196385.1| P450 heme-thiolate protein [Nocardioidaceae bacterium Broad-1]
 gi|325952279|gb|EGD44305.1| P450 heme-thiolate protein [Nocardioidaceae bacterium Broad-1]
Length=446

 Score =  386 bits (992),  Expect = 4e-105, Method: Compositional matrix adjust.
 Identities = 206/432 (48%), Positives = 265/432 (62%), Gaps = 5/432 (1%)

Query  59   GDAGLPILGHMIEMLRGGPDYLMFLYKTKGPVVFGDSAVLPGVAALGPDAAQVIYSNRNK  118
            GD GLP +G +++  R    +    ++T GPV     A   GV  LGPDA + +  N++K
Sbjct  16   GDRGLPWVGRLLDYSRDPVGFYRHQWETYGPVSPFFRAGETGVVVLGPDACEAVLRNKDK  75

Query  119  DYSQQ-GWVPVIGPFFHRGLMLLDFEEHMFHRRIMQEAFVRSRLAGYLEQMDRVVSRVVA  177
             Y+    W  ++GPFF RGLMLLDFEEH  HRRIMQEAF R RLA Y   M   +++ + 
Sbjct  76   AYANGPAWGQIVGPFFDRGLMLLDFEEHHVHRRIMQEAFTRDRLATYTTAMHPAIAQGI-  134

Query  178  DDWVVNDARFLVYPAMKALTLDIASMVFMGHEPGTDHELVTKVNKAFTITTRAGNAVIRT  237
              W  N   F  YP +K LTLDIA+ +FMG    T    + +VN+AF    +A   V+R 
Sbjct  135  RGWA-NAPAFQSYPRLKQLTLDIAADIFMGGAAETSRAEMDRVNRAFIACVQAAAGVVRA  193

Query  238  SVPPFTWWRGLRARELLENYFTARVKERREASGNDLLTVLCQTEDDDGNRFSDADIVNHM  297
             VP   W R  R R++LE +    +  +R    +D+ +VLC  E DDG RFSD D+VNHM
Sbjct  194  DVPFTRWGRAFRGRKVLEGFLRHYLPAKRAQQTDDIFSVLCHIETDDGERFSDEDVVNHM  253

Query  298  IFLMMAAHDTSTSTATTMAYQLAAHPEWQQRCRDESDRHGDGPLDIESLEQLESLDLVMN  357
            IFLMMAAHDTST T +TM   L  HP+WQQRCR+ES   G  P   E +E L SLDLVM 
Sbjct  254  IFLMMAAHDTSTITTSTMLQYLGQHPQWQQRCREESLALGPAPTMAE-IESLTSLDLVMK  312

Query  358  ESIRLVTPVQWAMRQTVRDTELLGYYLPKGTNVIAYPGMNHRLPEIWTDPLTFDPERFTE  417
            E++RL  PV   +R+TV++T LLG  +P  T V+     +H + + WT+P  FDPERF  
Sbjct  313  EALRLRAPVPALIRRTVKETRLLGVRIPADTAVMVGVQFSHMMEDYWTNPTVFDPERFAP  372

Query  418  PRNEHKRHRYAFTPFGGGVHKCIGMVFDQLEIKTILHRLLRRYRLELSRPDYQPRWDYSA  477
             R E K HR A+ PFGGGVHKCIG+ F  LE+K+ILHRLLR YR  +S P Y+   D S+
Sbjct  373  HRREDKSHRMAWEPFGGGVHKCIGLYFAGLEVKSILHRLLRDYRWSVS-PGYRAPLDNSS  431

Query  478  MPIPMDGMPIVL  489
            +P P DG PI L
Sbjct  432  LPFPKDGNPIHL  443


>gi|321176309|gb|ADW77638.1| cytochrome P450 [Rhodococcus sp. R04]
Length=459

 Score =  386 bits (991),  Expect = 6e-105, Method: Compositional matrix adjust.
 Identities = 203/449 (46%), Positives = 276/449 (62%), Gaps = 4/449 (0%)

Query  45   LAEPPPGSGLKPVVGDAGLPILGHMIEMLRGGPDYLMFLYKTKGPVVFGDSAVLPGVAAL  104
            LA PP  S L+PV G +G+P +GH++E +R     +   +   G V    +A    ++ L
Sbjct  5    LAAPPAHSHLRPVPGRSGIPGIGHVLEYIRNPLAMMQKHWDRYGEVSCFSAAGRRWISVL  64

Query  105  GPDAAQVIYSNRNKDYSQ-QGWVPVIGPFFHRGLMLLDFEEHMFHRRIMQEAFVRSRLAG  163
            GPDA Q +  N+++ ++   GW  +IGPFFH GLMLLD EEH+ HRRIMQ+AF RSRL  
Sbjct  65   GPDACQEVLQNKDRAFANGDGWSALIGPFFHGGLMLLDSEEHLRHRRIMQQAFTRSRLEK  124

Query  164  YLEQMDRVVSRVVADDWVVNDARFLVYPAMKALTLDIASMVFMGHEPGTDHELVTKVNKA  223
             ++ M+  +++ + D WV +D  F  Y A+K LTLD+A+ +FMG    +    +  V KA
Sbjct  125  TVDAMNPSIAQKL-DRWVPSDG-FRAYTALKTLTLDLATDIFMGGAEDSTPAEIEVVKKA  182

Query  224  FTITTRAGNAVIRTSVPPFTWWRGLRARELLENYFTARVKERREASGNDLLTVLCQTEDD  283
            F    +A  +++R  VP   W RGL  R +LE++F   +  RR    +DL +VLC  E +
Sbjct  183  FIDCVQAATSIVRYPVPGTRWKRGLDGRRVLEDFFRHYLPARRSRETDDLFSVLCHIESE  242

Query  284  DGNRFSDADIVNHMIFLMMAAHDTSTSTATTMAYQLAAHPEWQQRCRDESDRHGDGPLDI  343
             G RFSD +IV+HMIFL+MAAHDTST T +TM   L  HP+WQ RCR ES   G      
Sbjct  243  AGQRFSDDEIVDHMIFLLMAAHDTSTITISTMMQYLGQHPQWQDRCRAESLALGTAAPSH  302

Query  344  ESLEQLESLDLVMNESIRLVTPVQWAMRQTVRDTELLGYYLPKGTNVIAYPGMNHRLPEI  403
              L+ L SLDLVM E +RLV+PV    R+ VRDTE+ GY++P GT     P   H + E 
Sbjct  303  ADLDALGSLDLVMKECLRLVSPVPVLARRAVRDTEVRGYFVPAGTYASVAPHFTHHMAEY  362

Query  404  WTDPLTFDPERFTEPRNEHKRHRYAFTPFGGGVHKCIGMVFDQLEIKTILHRLLRRYRLE  463
            W +P  FDPERF E R E K HRYA+ PFGGGVHKC+GM F  +E+K I+H+LL R+   
Sbjct  363  WPEPERFDPERFAEHRREDKVHRYAWEPFGGGVHKCLGMHFAGVEVKAIVHQLLLRFEWH  422

Query  464  LSRPDYQPRWDYSAMPIPMDGMPIVLRPR  492
            +  P Y    D++++P P DG P+ LR R
Sbjct  423  VD-PGYVAPLDFTSLPFPSDGQPVDLRLR  450


>gi|229493038|ref|ZP_04386833.1| cytochrome P450 [Rhodococcus erythropolis SK121]
 gi|229320068|gb|EEN85894.1| cytochrome P450 [Rhodococcus erythropolis SK121]
Length=457

 Score =  385 bits (990),  Expect = 7e-105, Method: Compositional matrix adjust.
 Identities = 203/451 (46%), Positives = 272/451 (61%), Gaps = 4/451 (0%)

Query  42   EKKLAEPPPGSGLKPVVGDAGLPILGHMIEMLRGGPDYLMFLYKTKGPVVFGDSAVLPGV  101
             K LA PP  S L+P+ G++GLP +G   E +R     +   +   G V +   A    V
Sbjct  3    SKILAAPPIRSQLRPISGNSGLPGIGQTFEYIRDPLALMQKRWDRYGEVSWFSMAGRRWV  62

Query  102  AALGPDAAQVIYSNRNKDY-SQQGWVPVIGPFFHRGLMLLDFEEHMFHRRIMQEAFVRSR  160
            AALGPDA Q +  N+++ + +  GW  +IGPFFH GLMLLD EEH+  RRIMQ+AF RSR
Sbjct  63   AALGPDACQEVLQNKDRAFVNSDGWSVLIGPFFHGGLMLLDSEEHLRQRRIMQQAFTRSR  122

Query  161  LAGYLEQMDRVVSRVVADDWVVNDARFLVYPAMKALTLDIASMVFMGHEPGTDHELVTKV  220
            L   ++ ++  ++  + D W  +D  F  Y A+KALTL++A+ +FMG   GT    +  V
Sbjct  123  LEKTVDVLNPAIASAL-DAWTPSDG-FRAYTALKALTLNLATDIFMGGAEGTTESEIDSV  180

Query  221  NKAFTITTRAGNAVIRTSVPPFTWWRGLRARELLENYFTARVKERREASGNDLLTVLCQT  280
             KAF    +A  +VIR  VP   W RGL  R  LEN+F   +  RR    +DL +VLC  
Sbjct  181  KKAFVDCVQAATSVIRYRVPGTRWKRGLDGRRTLENFFRRYLPARRSRETDDLFSVLCHI  240

Query  281  EDDDGNRFSDADIVNHMIFLMMAAHDTSTSTATTMAYQLAAHPEWQQRCRDESDRHGDGP  340
            E D G RFSD ++++HMIFL+MAAHDTST T +TM   L  +P+WQ RCR ES       
Sbjct  241  ESDTGQRFSDGEVIDHMIFLLMAAHDTSTITISTMMQYLGQNPQWQNRCRAESLALSTST  300

Query  341  LDIESLEQLESLDLVMNESIRLVTPVQWAMRQTVRDTELLGYYLPKGTNVIAYPGMNHRL  400
                 L+QL  LDLVM E +RLV PV    R+ V DT++  +++P GT V   P   H +
Sbjct  301  PSYAELDQLAGLDLVMKECLRLVAPVPVMARRAVCDTQIQDHFVPAGTYVSVVPHFTHHM  360

Query  401  PEIWTDPLTFDPERFTEPRNEHKRHRYAFTPFGGGVHKCIGMVFDQLEIKTILHRLLRRY  460
            P+ W DP  FDPERF + R E K HRYA+ PFGGGVHKC+GM F  +EIK I+H LL R+
Sbjct  361  PQYWPDPEHFDPERFADHRREDKVHRYAWEPFGGGVHKCLGMHFAGIEIKAIMHHLLTRF  420

Query  461  RLELSRPDYQPRWDYSAMPIPMDGMPIVLRP  491
              +++ P Y    +Y ++P P DG PI L+P
Sbjct  421  DWQVA-PGYTAPLNYMSLPFPSDGQPIDLKP  450


>gi|226308490|ref|YP_002768450.1| cytochrome P450 [Rhodococcus erythropolis PR4]
 gi|226187607|dbj|BAH35711.1| putative cytochrome P450 [Rhodococcus erythropolis PR4]
Length=455

 Score =  382 bits (982),  Expect = 6e-104, Method: Compositional matrix adjust.
 Identities = 198/452 (44%), Positives = 272/452 (61%), Gaps = 4/452 (0%)

Query  42   EKKLAEPPPGSGLKPVVGDAGLPILGHMIEMLRGGPDYLMFLYKTKGPVVFGDSAVLPGV  101
             K LA PP  S L P+ G +GLP++GH +  +R     +   +   G V +        +
Sbjct  2    SKILARPPMNSQLHPISGRSGLPLVGHALAYIRDPLALMQENWDRYGEVSWFSMVGRQWI  61

Query  102  AALGPDAAQVIYSNRNKDY-SQQGWVPVIGPFFHRGLMLLDFEEHMFHRRIMQEAFVRSR  160
            A LGPDA Q +  N+++ + +  GW  +IGPFFH GLMLLD EEH+ HRRIMQ+AF R+R
Sbjct  62   AVLGPDACQEVLQNKDRAFVNSDGWSVLIGPFFHGGLMLLDSEEHLRHRRIMQQAFTRTR  121

Query  161  LAGYLEQMDRVVSRVVADDWVVNDARFLVYPAMKALTLDIASMVFMGHEPGTDHELVTKV  220
            +   ++ ++  +   + D W   D  F  Y A+K LTLD+A+ +FMG   G+    ++ V
Sbjct  122  IEKSVDVLNPAIDSAL-DTWTPTDG-FRAYTALKTLTLDLATDIFMGGAEGSTESEISSV  179

Query  221  NKAFTITTRAGNAVIRTSVPPFTWWRGLRARELLENYFTARVKERREASGNDLLTVLCQT  280
             KAF    +A  +++R  VP   W RGL  R +LE++F   +  RR  + +DL +VLC  
Sbjct  180  KKAFVDCVQAATSLVRYRVPGTRWKRGLDGRRVLEDFFRRYLPARRARATDDLFSVLCHI  239

Query  281  EDDDGNRFSDADIVNHMIFLMMAAHDTSTSTATTMAYQLAAHPEWQQRCRDESDRHGDGP  340
            E + G RFSD ++++HMIFL+MAAHDTST T +TM   L  HP+WQ RCR ES   G   
Sbjct  240  ESEAGQRFSDDEVIDHMIFLLMAAHDTSTITLSTMMQYLGQHPKWQDRCRAESLALGTST  299

Query  341  LDIESLEQLESLDLVMNESIRLVTPVQWAMRQTVRDTELLGYYLPKGTNVIAYPGMNHRL  400
                 L+ L SLDLVM E +RLV+PV    R+ VRDT++ G+++P GT V   P   H +
Sbjct  300  PSYADLDGLSSLDLVMKECLRLVSPVPVMARRAVRDTQVRGHFVPAGTYVSVAPHFTHHM  359

Query  401  PEIWTDPLTFDPERFTEPRNEHKRHRYAFTPFGGGVHKCIGMVFDQLEIKTILHRLLRRY  460
             + W DP  FDPERF E R E K HRYA+ PFGGGVHKC+GM F   EIK I+H LL R+
Sbjct  360  AQYWPDPERFDPERFAENRREDKVHRYAWEPFGGGVHKCLGMHFAGAEIKAIMHHLLMRF  419

Query  461  RLELSRPDYQPRWDYSAMPIPMDGMPIVLRPR  492
               +   DY    D++++P P DG P+ LR R
Sbjct  420  DWNVD-ADYVAPLDFTSLPFPSDGQPVDLRRR  450


>gi|311742069|ref|ZP_07715879.1| P450 heme-thiolate protein [Aeromicrobium marinum DSM 15272]
 gi|311314562|gb|EFQ84469.1| P450 heme-thiolate protein [Aeromicrobium marinum DSM 15272]
Length=448

 Score =  378 bits (971),  Expect = 1e-102, Method: Compositional matrix adjust.
 Identities = 196/428 (46%), Positives = 267/428 (63%), Gaps = 5/428 (1%)

Query  63   LPILGHMIEMLRGGPDYLMFLYKTKGPVVFGDSAVLPGVAALGPDAAQVIYSNRNKDY-S  121
            +P++G  +  +R     +   Y   GPV           A LGPDA +    N +K + S
Sbjct  17   VPLVGRTLAYVRDPLAMMRDQYDRSGPVSDITFIGRTWTALLGPDACEAALRNGDKAFAS  76

Query  122  QQGWVPVIGPFFHRGLMLLDFEEHMFHRRIMQEAFVRSRLAGYLEQMDRVVSRVVADDWV  181
            + GW  ++GPFFHRGLMLLDF EH  HRR+MQEAF R RL GY  ++   V+  + D W 
Sbjct  77   EDGWGYLVGPFFHRGLMLLDFAEHHQHRRLMQEAFTRDRLRGYTARLGPAVTAGL-DAWR  135

Query  182  VNDARFLVYPAMKALTLDIASMVFMGHEPGTDHELVTKVNKAFTITTRAGNAVIRTSVPP  241
              D  FL YPA+K LTLD+A+ +FMG     D   + ++N+AF    +A  A IR  +P 
Sbjct  136  PGDD-FLAYPALKQLTLDLATQIFMGGADLADDAELDRLNRAFIDCVQAATAFIRVPLPG  194

Query  242  FTWWRGLRARELLENYFTARVKERREASGNDLLTVLCQTEDDDGNRFSDADIVNHMIFLM  301
              W R  + R+LLE +    +  +R + G DL +VLC+  DDDG+ F+D D+VNHMIFL+
Sbjct  195  TRWGRATKGRKLLEEFLYRHIDTKRASDGEDLFSVLCRLTDDDGSAFTDEDVVNHMIFLL  254

Query  302  MAAHDTSTSTATTMAYQLAAHPEWQQRCRDESDRHGDGPLDIESLEQLESLDLVMNESIR  361
            MAAHDTST T +TM   L  HPEWQ+RCR ES   GD P  ++ L+ L SLDLVM E +R
Sbjct  255  MAAHDTSTITVSTMMQYLGQHPEWQERCRAESMALGDHPT-LDELDTLTSLDLVMKECLR  313

Query  362  LVTPVQWAMRQTVRDTELLGYYLPKGTNVIAYPGMNHRLPEIWTDPLTFDPERFTEPRNE  421
            +V PV    R+TV++TE+LG+ +P G   +    ++H +PE+W DP  FDPERF E R +
Sbjct  314  IVPPVPVLARKTVKETEVLGHTIPAGRLTVVMMHLSHHMPELWEDPERFDPERFAEDRRD  373

Query  422  HKRHRYAFTPFGGGVHKCIGMVFDQLEIKTILHRLLRRYRLELSRPDYQPRWDYSAMPIP  481
             K HRYA+ PFGGGVHKC+G+ F   E+ TI+H+LLRR+  E+  PDY+   +Y ++P P
Sbjct  374  DKVHRYAWEPFGGGVHKCLGLHFAGAEVSTIMHQLLRRFSWEVD-PDYRAPMNYHSLPFP  432

Query  482  MDGMPIVL  489
             DG P+ L
Sbjct  433  SDGQPVDL  440


>gi|325673495|ref|ZP_08153186.1| P450 heme-thiolate protein [Rhodococcus equi ATCC 33707]
 gi|325555516|gb|EGD25187.1| P450 heme-thiolate protein [Rhodococcus equi ATCC 33707]
Length=469

 Score =  378 bits (970),  Expect = 1e-102, Method: Compositional matrix adjust.
 Identities = 198/451 (44%), Positives = 269/451 (60%), Gaps = 4/451 (0%)

Query  43   KKLAEPPPGSGLKPVVGDAGLPILGHMIEMLRGGPDYLMFLYKTKGPVVFGDSAVLPGVA  102
            K LA+PP  SGL+PV G  GLP++G ++  +R     +   +   G + +        +A
Sbjct  10   KLLADPPTQSGLRPVAGRPGLPLVGQVLAYIRDPLALMQRQWDRYGEISWFSMLGRRWLA  69

Query  103  ALGPDAAQVIYSNRNKDYSQ-QGWVPVIGPFFHRGLMLLDFEEHMFHRRIMQEAFVRSRL  161
             LGPDA Q +  N+++ ++   GW  +IGPFFH GLMLLD EEH+ HRRIMQ+AF R+RL
Sbjct  70   VLGPDACQEVLQNKDRAFANGDGWSVLIGPFFHGGLMLLDSEEHLRHRRIMQQAFTRARL  129

Query  162  AGYLEQMDRVVSRVVADDWVVNDARFLVYPAMKALTLDIASMVFMGHEPGTDHELVTKVN  221
               +  +   +   +   W   +  F  Y A+KALTLD+A+ +FMG   G     +  V 
Sbjct  130  EKTVAALHPAIDSAL-QGWTPTEG-FRAYTALKALTLDLATDIFMGGAEGATDSEIASVQ  187

Query  222  KAFTITTRAGNAVIRTSVPPFTWWRGLRARELLENYFTARVKERREASGNDLLTVLCQTE  281
            KAF    +A  +VIR  VP   W RGL  R +LE++F   +  RR    +DL +VLC  E
Sbjct  188  KAFVDCVQAATSVIRRPVPGTRWKRGLDGRRVLEDFFHRYLPARRARETDDLFSVLCHIE  247

Query  282  DDDGNRFSDADIVNHMIFLMMAAHDTSTSTATTMAYQLAAHPEWQQRCRDESDRHGDGPL  341
             D G RF+D ++++HMIFL+MAAHDTST T +TM   L  HP+WQ RCR ES   G    
Sbjct  248  ADAGQRFADDEVIDHMIFLLMAAHDTSTITLSTMMQYLGQHPQWQDRCRAESLALGTSTP  307

Query  342  DIESLEQLESLDLVMNESIRLVTPVQWAMRQTVRDTELLGYYLPKGTNVIAYPGMNHRLP  401
                L+ L+SLDLVM E +R+V+PV    R+ VRDT++ G+++P GT     P   H + 
Sbjct  308  SHAELDGLDSLDLVMKECLRIVSPVPVVARRAVRDTQVRGHFVPAGTYAAVAPHFTHHMA  367

Query  402  EIWTDPLTFDPERFTEPRNEHKRHRYAFTPFGGGVHKCIGMVFDQLEIKTILHRLLRRYR  461
            E W DP  FDPERF   R E K HRYA+ PFGGGVHKC+GM F   EIK I+H LL R+ 
Sbjct  368  EYWPDPECFDPERFAPHRREDKVHRYAWEPFGGGVHKCLGMHFAGAEIKAIMHHLLLRFD  427

Query  462  LELSRPDYQPRWDYSAMPIPMDGMPIVLRPR  492
             ++   DY    D++++P P DG P+ LR R
Sbjct  428  WQVD-ADYVAPLDFTSLPFPSDGQPVDLRLR  457


>gi|108801810|ref|YP_642007.1| cytochrome P450 [Mycobacterium sp. MCS]
 gi|119870962|ref|YP_940914.1| cytochrome P450 [Mycobacterium sp. KMS]
 gi|108772229|gb|ABG10951.1| cytochrome P450 [Mycobacterium sp. MCS]
 gi|119697051|gb|ABL94124.1| cytochrome P450 [Mycobacterium sp. KMS]
Length=480

 Score =  374 bits (959),  Expect = 3e-101, Method: Compositional matrix adjust.
 Identities = 204/465 (44%), Positives = 278/465 (60%), Gaps = 12/465 (2%)

Query  31   VEHMLLNTKFP--EKKLAEPPPGSGLKPVVGDAGLPILGHMIEMLRGGPDYLMFLYKTKG  88
            V    L ++FP  E+ LA PPPGS LKPV+G+ G P LGH +  L    D+    Y   G
Sbjct  19   VAGAALTSRFPSREEPLATPPPGSNLKPVMGNYGFPFLGHTLSALAEPLDFARRRYDMYG  78

Query  89   PVVFGDSAVLPGVAALGPDAAQVIYSNRNKDYSQ-QGWVPVIGPFFHRGLMLLDFEEHMF  147
            PV +        VA +GPDA +  + NR+K +S  +GW PVIGPFFHRG+MLLDFEEH  
Sbjct  79   PVSWAGGVGFRVVALMGPDALETAWINRDKVFSSTRGWAPVIGPFFHRGIMLLDFEEHRD  138

Query  148  HRRIMQEAFVRSRLAGYLEQMDRVVSRVVADDWVVNDARFLVYPAMKALTLDIASMVFMG  207
            HRRIMQ+AF R+ L GYLE M   + R +   W  +DA F  YP++K L L+ A+ VF+G
Sbjct  139  HRRIMQQAFARTALDGYLELMRPGIDRTLGG-WPASDA-FPFYPSIKHLLLEQAAEVFVG  196

Query  208  HEPGTDHELVTKVNKAFTITTRAGNAVIRTSVPPFTWWRGLRARELLENYFTARVKERRE  267
               G + +   +++  F  T R G A++R  VP   W RGLRAR+ LE YF  ++ +R+ 
Sbjct  197  THLGPESD---QLSADFHDTVRGGQALLRADVPGGVWARGLRARKRLERYFGDQIADRQR  253

Query  268  ASGNDLLTVLCQTEDDDGNRFSDADIVNHMIFLMMAAHDTSTSTATTMAYQLAAHPEWQQ  327
              G DL ++LC++EDDDG RF+ ADIVNHMIFL+MAAHDT+    + + Y+L  + +WQ+
Sbjct  254  GDGADLFSMLCRSEDDDGARFTPADIVNHMIFLLMAAHDTTAIALSMLVYELGRNQKWQK  313

Query  328  RCRDES-DRHGDGPLDIESLEQLESLDLVMNESIRLVTPVQWAMRQTVRDTELLGYYLPK  386
              RDE+  R  D P  +  L+    LD    E +R+  P     RQT RDT++LG+++P 
Sbjct  314  TLRDEAVGRPNDAPA-VGDLDAYPLLDAAFKEILRMYAPAGTLFRQTTRDTDILGHFVPA  372

Query  387  GTNVIAYPGMNHRLPEIWTDPLTFDPERFT-EPRNEHKRHRYAFTPFGGGVHKCIGMVFD  445
             T V      + RL + W DP TFDP RF  +P       RYAF PFGGG HKCIG  F 
Sbjct  373  KTQVAINVHASMRLADWWPDPDTFDPARFIDQPGARAAVSRYAFAPFGGGAHKCIGQQFA  432

Query  446  QLEIKTILHRLLRRYRLELSRPDYQPRWDYSAMPIPMDGMPIVLR  490
             + +KT +H++LRR+   ++   Y+    +   P P D +PI LR
Sbjct  433  DMTVKTTMHQMLRRFEWSVAD-GYRIPLTWGTGPTPADDLPITLR  476


>gi|126437779|ref|YP_001073470.1| cytochrome P450 [Mycobacterium sp. JLS]
 gi|126237579|gb|ABO00980.1| cytochrome P450 [Mycobacterium sp. JLS]
Length=480

 Score =  373 bits (958),  Expect = 4e-101, Method: Compositional matrix adjust.
 Identities = 204/465 (44%), Positives = 277/465 (60%), Gaps = 12/465 (2%)

Query  31   VEHMLLNTKFP--EKKLAEPPPGSGLKPVVGDAGLPILGHMIEMLRGGPDYLMFLYKTKG  88
            V    L ++FP  E+ LA PPPGS LKPV G+ G P LGH +  L    D+    Y   G
Sbjct  19   VAGAALTSRFPSREEPLATPPPGSNLKPVTGNYGFPFLGHTLSALAEPLDFARRRYDMYG  78

Query  89   PVVFGDSAVLPGVAALGPDAAQVIYSNRNKDYSQ-QGWVPVIGPFFHRGLMLLDFEEHMF  147
            PV +        VA +GPDA +  + NR+K +S  +GW PVIGPFFHRG+MLLDFEEH  
Sbjct  79   PVSWAGGVGFRVVALMGPDALETAWINRDKVFSSTRGWAPVIGPFFHRGIMLLDFEEHRD  138

Query  148  HRRIMQEAFVRSRLAGYLEQMDRVVSRVVADDWVVNDARFLVYPAMKALTLDIASMVFMG  207
            HRRIMQ+AF R+ L GYLE M   + R +   W  +DA F  YP++K L L+ A+ VF+G
Sbjct  139  HRRIMQQAFTRTALDGYLELMRPGIDRTLGG-WPASDA-FPFYPSIKHLLLEQAAEVFVG  196

Query  208  HEPGTDHELVTKVNKAFTITTRAGNAVIRTSVPPFTWWRGLRARELLENYFTARVKERRE  267
               G + +   +++  F  T R G A++R  VP   W RGLRAR+ LE YF  ++ +R+ 
Sbjct  197  THLGPESD---QLSADFHDTVRGGQALLRADVPGGVWARGLRARKRLERYFGDQIADRQR  253

Query  268  ASGNDLLTVLCQTEDDDGNRFSDADIVNHMIFLMMAAHDTSTSTATTMAYQLAAHPEWQQ  327
              G DL ++LC++EDDDG RF+ ADIVNHMIFL+MAAHDT+    + + Y+L  + +WQ+
Sbjct  254  GDGADLFSMLCRSEDDDGARFTPADIVNHMIFLLMAAHDTTAIALSMLVYELGRNQKWQK  313

Query  328  RCRDES-DRHGDGPLDIESLEQLESLDLVMNESIRLVTPVQWAMRQTVRDTELLGYYLPK  386
              RDE+  R  D P  +  L+    LD    E +R+  P     RQT RDT++LG+++P 
Sbjct  314  TLRDEAVGRPNDAPA-VGDLDAYPLLDAAFKEILRMYAPAGTLFRQTTRDTDILGHFVPA  372

Query  387  GTNVIAYPGMNHRLPEIWTDPLTFDPERFT-EPRNEHKRHRYAFTPFGGGVHKCIGMVFD  445
             T V      + RL + W DP TFDP RF  +P       RYAF PFGGG HKCIG  F 
Sbjct  373  KTQVAINVHASMRLADWWPDPDTFDPARFIDQPGARAAVSRYAFAPFGGGAHKCIGQQFA  432

Query  446  QLEIKTILHRLLRRYRLELSRPDYQPRWDYSAMPIPMDGMPIVLR  490
             + +KT +H++LRR+   ++   Y+    +   P P D +PI LR
Sbjct  433  DMTVKTTMHQMLRRFEWSVAD-GYRIPLTWGTGPTPADDLPITLR  476



Lambda     K      H
   0.323    0.139    0.432 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Effective search space used: 1053329043408


  Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
    Posted date:  Sep 5, 2011  4:36 AM
  Number of letters in database: 5,219,829,388
  Number of sequences in database:  15,229,318



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40