BLASTP 2.2.25+
Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
15,229,318 sequences; 5,219,829,388 total letters
Query= Rv3065
Length=107
Score E
Sequences producing significant alignments: (Bits) Value
gi|15842634|ref|NP_337671.1| emrE protein [Mycobacterium tubercu... 203 5e-51
gi|240170696|ref|ZP_04749355.1| transporter, small multidrug res... 176 8e-43
gi|118462364|ref|YP_883109.1| transporter, small multidrug resis... 175 2e-42
gi|57012894|sp|Q73V87.2|MMR_MYCPA RecName: Full=Multidrug resist... 174 3e-42
gi|41409225|ref|NP_962061.1| EmrE [Mycobacterium avium subsp. pa... 173 6e-42
gi|254820751|ref|ZP_05225752.1| transporter, small multidrug res... 172 1e-41
gi|254776368|ref|ZP_05217884.1| transporter, small multidrug res... 172 2e-41
gi|15827941|ref|NP_302204.1| multidrug resistance protein [Mycob... 167 6e-40
gi|342860914|ref|ZP_08717563.1| transporter, small multidrug res... 166 7e-40
gi|296171089|ref|ZP_06852542.1| DMT superfamily multidrug transp... 166 1e-39
gi|183981627|ref|YP_001849918.1| multidrug-transport integral me... 150 4e-35
gi|118618737|ref|YP_907069.1| multidrug-transport integral membr... 147 6e-34
gi|120401364|ref|YP_951193.1| small multidrug resistance protein... 135 2e-30
gi|330466683|ref|YP_004404426.1| small multidrug resistance prot... 124 6e-27
gi|302866671|ref|YP_003835308.1| small multidrug resistance prot... 121 4e-26
gi|337763591|emb|CCB72301.1| Multidrug resistance protein [Strep... 117 8e-25
gi|302546206|ref|ZP_07298548.1| EmrE protein [Streptomyces hygro... 107 6e-22
gi|239986857|ref|ZP_04707521.1| putative SMR-type multi-drug eff... 105 2e-21
gi|344998943|ref|YP_004801797.1| small multidrug resistance prot... 100 9e-20
gi|291440359|ref|ZP_06579749.1| SMR-type multi-drug efflux trans... 98.2 4e-19
gi|328881596|emb|CCA54835.1| Ethidium bromide-methyl viologen re... 97.8 5e-19
gi|302546313|ref|ZP_07298655.1| multidrug transporter EmrE [Stre... 96.7 9e-19
gi|302533772|ref|ZP_07286114.1| conserved hypothetical protein [... 96.7 1e-18
gi|290961361|ref|YP_003492543.1| protein [Streptomyces scabiei 8... 95.5 2e-18
gi|182439397|ref|YP_001827116.1| putative SMR-type multi-drug ef... 95.1 3e-18
gi|331699227|ref|YP_004335466.1| small multidrug resistance prot... 95.1 3e-18
gi|126650743|ref|ZP_01722959.1| multidrug resistance protein, SM... 94.0 6e-18
gi|297198855|ref|ZP_06916252.1| multidrug resistance efflux prot... 94.0 7e-18
gi|169827833|ref|YP_001697991.1| multidrug resistance protein [L... 93.6 8e-18
gi|295839577|ref|ZP_06826510.1| multidrug transporter EmrE [Stre... 92.8 2e-17
gi|89095990|ref|ZP_01168883.1| multidrug resistance protein [Bac... 92.0 2e-17
gi|302518365|ref|ZP_07270707.1| integral membrane protein [Strep... 92.0 3e-17
gi|333027965|ref|ZP_08456029.1| putative SMR-type multi-drug eff... 92.0 3e-17
gi|302550605|ref|ZP_07302947.1| multidrug resistance efflux prot... 92.0 3e-17
gi|163841151|ref|YP_001625556.1| quaternary ammonium compound-re... 91.7 3e-17
gi|302561298|ref|ZP_07313640.1| multidrug transporter EmrE [Stre... 91.7 3e-17
gi|311898957|dbj|BAJ31365.1| putative multidrug resistance prote... 91.3 4e-17
gi|297161463|gb|ADI11175.1| SMR-type multi-drug efflux transport... 90.9 5e-17
gi|329940791|ref|ZP_08290071.1| integral membrane protein [Strep... 90.9 6e-17
gi|257094493|ref|YP_003168134.1| small multidrug resistance prot... 90.9 6e-17
gi|134301118|ref|YP_001114614.1| small multidrug resistance prot... 90.5 7e-17
gi|54023944|ref|YP_118186.1| putative multi-drug efflux transpor... 90.5 7e-17
gi|345014302|ref|YP_004816656.1| small multidrug resistance prot... 89.7 1e-16
gi|1848269|gb|AAB47993.1| quaternary ammonium compounds resistan... 89.0 2e-16
gi|88800946|ref|ZP_01116498.1| multidrug resistance protein [Rei... 89.0 2e-16
gi|298504825|gb|ADI83548.1| small multidrug resistance family tr... 88.6 3e-16
gi|299536851|ref|ZP_07050158.1| multidrug resistance protein [Ly... 88.6 3e-16
gi|34498135|ref|NP_902350.1| quaternary ammonium compound resist... 87.8 5e-16
gi|300716358|ref|YP_003741161.1| hypothetical protein EbC_17790 ... 87.4 6e-16
gi|337750354|ref|YP_004644516.1| multidrug resistance protein [P... 86.7 1e-15
>gi|15842634|ref|NP_337671.1| emrE protein [Mycobacterium tuberculosis CDC1551]
gi|31794244|ref|NP_856737.1| multidrugs-transport integral membrane protein MMR [Mycobacterium
bovis AF2122/97]
gi|57117052|ref|YP_177922.1| multidrugs-transport integral membrane protein MMR [Mycobacterium
tuberculosis H37Rv]
82 more sequence titles
Length=107
Score = 203 bits (517), Expect = 5e-51, Method: Compositional matrix adjust.
Identities = 106/107 (99%), Positives = 107/107 (100%), Gaps = 0/107 (0%)
Query 1 LIYLYLLCAIFAEVVATSLLKSTEGFTRLWPTVGCLVGYGIAFALLALSISHGMQTDVAY 60
+IYLYLLCAIFAEVVATSLLKSTEGFTRLWPTVGCLVGYGIAFALLALSISHGMQTDVAY
Sbjct 1 MIYLYLLCAIFAEVVATSLLKSTEGFTRLWPTVGCLVGYGIAFALLALSISHGMQTDVAY 60
Query 61 ALWSAIGTAAIVLVAVLFLGSPISVMKVVGVGLIVVGVVTLNLAGAH 107
ALWSAIGTAAIVLVAVLFLGSPISVMKVVGVGLIVVGVVTLNLAGAH
Sbjct 61 ALWSAIGTAAIVLVAVLFLGSPISVMKVVGVGLIVVGVVTLNLAGAH 107
>gi|240170696|ref|ZP_04749355.1| transporter, small multidrug resistance (SMR) family protein
[Mycobacterium kansasii ATCC 12478]
Length=107
Score = 176 bits (447), Expect = 8e-43, Method: Compositional matrix adjust.
Identities = 89/105 (85%), Positives = 98/105 (94%), Gaps = 0/105 (0%)
Query 3 YLYLLCAIFAEVVATSLLKSTEGFTRLWPTVGCLVGYGIAFALLALSISHGMQTDVAYAL 62
YL+L CAIFAEVVATSLLKSTEGFTRLWPTV CL GY +AFALLALSI+ GMQTDVAYAL
Sbjct 3 YLFLFCAIFAEVVATSLLKSTEGFTRLWPTVVCLTGYAVAFALLALSIARGMQTDVAYAL 62
Query 63 WSAIGTAAIVLVAVLFLGSPISVMKVVGVGLIVVGVVTLNLAGAH 107
WSAIGTAAIVL+AVLFLGSP+S+ KV+GVGLI+ GV+TLNLAGAH
Sbjct 63 WSAIGTAAIVLIAVLFLGSPVSLAKVLGVGLIIGGVLTLNLAGAH 107
>gi|118462364|ref|YP_883109.1| transporter, small multidrug resistance (SMR) family protein
[Mycobacterium avium 104]
gi|118163651|gb|ABK64548.1| transporter, small multidrug resistance (SMR) family protein
[Mycobacterium avium 104]
Length=114
Score = 175 bits (443), Expect = 2e-42, Method: Compositional matrix adjust.
Identities = 89/107 (84%), Positives = 98/107 (92%), Gaps = 0/107 (0%)
Query 1 LIYLYLLCAIFAEVVATSLLKSTEGFTRLWPTVGCLVGYGIAFALLALSISHGMQTDVAY 60
L YL+L+CAI AEVVATSLLKST+GFTRLWPTV CL+GY ++FALLA+SIS GMQTDVAY
Sbjct 8 LTYLFLICAILAEVVATSLLKSTQGFTRLWPTVICLLGYAVSFALLAVSISRGMQTDVAY 67
Query 61 ALWSAIGTAAIVLVAVLFLGSPISVMKVVGVGLIVVGVVTLNLAGAH 107
ALWSAIGTA IVL+AVLFLGSPISV KVVGVGLI+ GVVTLNL GAH
Sbjct 68 ALWSAIGTALIVLIAVLFLGSPISVTKVVGVGLIIAGVVTLNLTGAH 114
>gi|57012894|sp|Q73V87.2|MMR_MYCPA RecName: Full=Multidrug resistance protein mmr
gi|336459227|gb|EGO38172.1| cation/cationic drug transporter [Mycobacterium avium subsp.
paratuberculosis S397]
Length=107
Score = 174 bits (442), Expect = 3e-42, Method: Compositional matrix adjust.
Identities = 88/107 (83%), Positives = 98/107 (92%), Gaps = 0/107 (0%)
Query 1 LIYLYLLCAIFAEVVATSLLKSTEGFTRLWPTVGCLVGYGIAFALLALSISHGMQTDVAY 60
+ YL+L+CAI AEVVATSLLKST+GFTRLWPTV CL+GY ++FALLA+SIS GMQTDVAY
Sbjct 1 MTYLFLICAILAEVVATSLLKSTQGFTRLWPTVICLLGYAVSFALLAVSISRGMQTDVAY 60
Query 61 ALWSAIGTAAIVLVAVLFLGSPISVMKVVGVGLIVVGVVTLNLAGAH 107
ALWSAIGTA IVL+AVLFLGSPISV KVVGVGLI+ GVVTLNL GAH
Sbjct 61 ALWSAIGTALIVLIAVLFLGSPISVTKVVGVGLIIAGVVTLNLTGAH 107
>gi|41409225|ref|NP_962061.1| EmrE [Mycobacterium avium subsp. paratuberculosis K-10]
gi|41398045|gb|AAS05675.1| EmrE [Mycobacterium avium subsp. paratuberculosis K-10]
Length=134
Score = 173 bits (439), Expect = 6e-42, Method: Compositional matrix adjust.
Identities = 89/107 (84%), Positives = 98/107 (92%), Gaps = 0/107 (0%)
Query 1 LIYLYLLCAIFAEVVATSLLKSTEGFTRLWPTVGCLVGYGIAFALLALSISHGMQTDVAY 60
L YL+L+CAI AEVVATSLLKST+GFTRLWPTV CL+GY ++FALLA+SIS GMQTDVAY
Sbjct 28 LTYLFLICAILAEVVATSLLKSTQGFTRLWPTVICLLGYAVSFALLAVSISRGMQTDVAY 87
Query 61 ALWSAIGTAAIVLVAVLFLGSPISVMKVVGVGLIVVGVVTLNLAGAH 107
ALWSAIGTA IVL+AVLFLGSPISV KVVGVGLI+ GVVTLNL GAH
Sbjct 88 ALWSAIGTALIVLIAVLFLGSPISVTKVVGVGLIIAGVVTLNLTGAH 134
>gi|254820751|ref|ZP_05225752.1| transporter, small multidrug resistance (SMR) family protein
[Mycobacterium intracellulare ATCC 13950]
Length=107
Score = 172 bits (436), Expect = 1e-41, Method: Compositional matrix adjust.
Identities = 89/107 (84%), Positives = 98/107 (92%), Gaps = 0/107 (0%)
Query 1 LIYLYLLCAIFAEVVATSLLKSTEGFTRLWPTVGCLVGYGIAFALLALSISHGMQTDVAY 60
+ YLYLL AIFAEVVATSLLKSTEGF+RLWPTV CL+GY I+FALLA+SIS GMQTDVAY
Sbjct 1 MTYLYLLGAIFAEVVATSLLKSTEGFSRLWPTVVCLIGYAISFALLAVSISRGMQTDVAY 60
Query 61 ALWSAIGTAAIVLVAVLFLGSPISVMKVVGVGLIVVGVVTLNLAGAH 107
ALWSAIGTA IVL+AVLFLGS IS+ KVVGVGLI+ GVVTLNL+GAH
Sbjct 61 ALWSAIGTALIVLIAVLFLGSSISLTKVVGVGLIIAGVVTLNLSGAH 107
>gi|254776368|ref|ZP_05217884.1| transporter, small multidrug resistance (SMR) family protein
[Mycobacterium avium subsp. avium ATCC 25291]
Length=107
Score = 172 bits (435), Expect = 2e-41, Method: Compositional matrix adjust.
Identities = 87/107 (82%), Positives = 97/107 (91%), Gaps = 0/107 (0%)
Query 1 LIYLYLLCAIFAEVVATSLLKSTEGFTRLWPTVGCLVGYGIAFALLALSISHGMQTDVAY 60
+ YL+L+CAI AEVVATSLLKST+GFTRLWPTV CL+GY +FALLA+SIS GMQTDVAY
Sbjct 1 MTYLFLICAILAEVVATSLLKSTQGFTRLWPTVICLLGYAASFALLAVSISRGMQTDVAY 60
Query 61 ALWSAIGTAAIVLVAVLFLGSPISVMKVVGVGLIVVGVVTLNLAGAH 107
ALWSAIGTA IVL+AVLFLGSPIS+ KVVGVGLI+ GVVTLNL GAH
Sbjct 61 ALWSAIGTALIVLIAVLFLGSPISMTKVVGVGLIIAGVVTLNLTGAH 107
>gi|15827941|ref|NP_302204.1| multidrug resistance protein [Mycobacterium leprae TN]
gi|221230418|ref|YP_002503834.1| putative multidrug resistance protein [Mycobacterium leprae Br4923]
gi|57012896|sp|Q9CBP1.1|MMR_MYCLE RecName: Full=Multidrug resistance protein mmr
gi|13093494|emb|CAC30709.1| probable multidrug resistance protein [Mycobacterium leprae]
gi|219933525|emb|CAR71851.1| probable multidrug resistance protein [Mycobacterium leprae Br4923]
Length=107
Score = 167 bits (422), Expect = 6e-40, Method: Compositional matrix adjust.
Identities = 83/105 (80%), Positives = 92/105 (88%), Gaps = 0/105 (0%)
Query 3 YLYLLCAIFAEVVATSLLKSTEGFTRLWPTVGCLVGYGIAFALLALSISHGMQTDVAYAL 62
YL+L CAIF EVVAT+LLKSTEGFTRL PT+ CL GY + F LLALSIS GM+TDVAYAL
Sbjct 3 YLFLFCAIFVEVVATTLLKSTEGFTRLVPTLACLAGYAVTFTLLALSISRGMKTDVAYAL 62
Query 63 WSAIGTAAIVLVAVLFLGSPISVMKVVGVGLIVVGVVTLNLAGAH 107
WSAIGTAAIVL+AVLFL SP+SV KVVGV LI+VGV+TLNLA AH
Sbjct 63 WSAIGTAAIVLIAVLFLDSPVSVAKVVGVALIIVGVITLNLADAH 107
>gi|342860914|ref|ZP_08717563.1| transporter, small multidrug resistance (SMR) family protein
[Mycobacterium colombiense CECT 3035]
gi|342131358|gb|EGT84628.1| transporter, small multidrug resistance (SMR) family protein
[Mycobacterium colombiense CECT 3035]
Length=107
Score = 166 bits (421), Expect = 7e-40, Method: Compositional matrix adjust.
Identities = 84/107 (79%), Positives = 97/107 (91%), Gaps = 0/107 (0%)
Query 1 LIYLYLLCAIFAEVVATSLLKSTEGFTRLWPTVGCLVGYGIAFALLALSISHGMQTDVAY 60
+ YL+LL AIFAEV+ATSLLKST+GF+RLWPTV CL+GY ++FALLA+SIS GMQTDVAY
Sbjct 1 MTYLFLLGAIFAEVIATSLLKSTDGFSRLWPTVVCLIGYAVSFALLAVSISRGMQTDVAY 60
Query 61 ALWSAIGTAAIVLVAVLFLGSPISVMKVVGVGLIVVGVVTLNLAGAH 107
ALWSAIGTA IVL+AVLFLGS IS+ KV+GVGLI+ GVVTLNL GAH
Sbjct 61 ALWSAIGTALIVLIAVLFLGSSISLTKVLGVGLIIAGVVTLNLTGAH 107
>gi|296171089|ref|ZP_06852542.1| DMT superfamily multidrug transporter EmrE [Mycobacterium parascrofulaceum
ATCC BAA-614]
gi|295894345|gb|EFG74098.1| DMT superfamily multidrug transporter EmrE [Mycobacterium parascrofulaceum
ATCC BAA-614]
Length=116
Score = 166 bits (420), Expect = 1e-39, Method: Compositional matrix adjust.
Identities = 84/107 (79%), Positives = 94/107 (88%), Gaps = 0/107 (0%)
Query 1 LIYLYLLCAIFAEVVATSLLKSTEGFTRLWPTVGCLVGYGIAFALLALSISHGMQTDVAY 60
L YL+L CAIF EV+ATSLLKST+GFTRLWPTV CL GY I+FALLALSI+ GMQTDVAY
Sbjct 10 LTYLFLFCAIFVEVIATSLLKSTDGFTRLWPTVVCLTGYAISFALLALSIARGMQTDVAY 69
Query 61 ALWSAIGTAAIVLVAVLFLGSPISVMKVVGVGLIVVGVVTLNLAGAH 107
ALWSAIGTA IVL+AVLFLGS I+V KV G+ LI+ GVVTLNL+GAH
Sbjct 70 ALWSAIGTALIVLIAVLFLGSTITVAKVAGIALIIAGVVTLNLSGAH 116
>gi|183981627|ref|YP_001849918.1| multidrug-transport integral membrane protein Mmr [Mycobacterium
marinum M]
gi|183174953|gb|ACC40063.1| multidrug-transport integral membrane protein Mmr [Mycobacterium
marinum M]
Length=107
Score = 150 bits (380), Expect = 4e-35, Method: Compositional matrix adjust.
Identities = 79/105 (76%), Positives = 90/105 (86%), Gaps = 0/105 (0%)
Query 3 YLYLLCAIFAEVVATSLLKSTEGFTRLWPTVGCLVGYGIAFALLALSISHGMQTDVAYAL 62
YL LL AI EV+ATS LKSTEGFTRLWPTV CL YG +FA+LA+SI+ GMQTDVAYAL
Sbjct 3 YLLLLGAIAMEVMATSFLKSTEGFTRLWPTVICLTVYGFSFAMLAMSIARGMQTDVAYAL 62
Query 63 WSAIGTAAIVLVAVLFLGSPISVMKVVGVGLIVVGVVTLNLAGAH 107
WSAIGT AIVL+AVLFLGS +S+ KV+GVGLI+ GV+TLNL GAH
Sbjct 63 WSAIGTGAIVLIAVLFLGSHLSLTKVLGVGLIIGGVLTLNLTGAH 107
>gi|118618737|ref|YP_907069.1| multidrug-transport integral membrane protein Mmr [Mycobacterium
ulcerans Agy99]
gi|118570847|gb|ABL05598.1| multidrug-transport integral membrane protein Mmr [Mycobacterium
ulcerans Agy99]
Length=107
Score = 147 bits (371), Expect = 6e-34, Method: Compositional matrix adjust.
Identities = 77/105 (74%), Positives = 88/105 (84%), Gaps = 0/105 (0%)
Query 3 YLYLLCAIFAEVVATSLLKSTEGFTRLWPTVGCLVGYGIAFALLALSISHGMQTDVAYAL 62
YL LL AI EV+ATS LKSTEGFTRLWPTV CL YG +FA+LA+S + GMQTDVAYAL
Sbjct 3 YLLLLGAIAMEVMATSFLKSTEGFTRLWPTVICLTIYGFSFAMLAMSTARGMQTDVAYAL 62
Query 63 WSAIGTAAIVLVAVLFLGSPISVMKVVGVGLIVVGVVTLNLAGAH 107
WSAIGT AIVL+ VLFLGS +S+ KV+GVGLI+ GV+TLNL GAH
Sbjct 63 WSAIGTGAIVLIVVLFLGSHLSLTKVLGVGLIIGGVLTLNLTGAH 107
>gi|120401364|ref|YP_951193.1| small multidrug resistance protein [Mycobacterium vanbaalenii
PYR-1]
gi|119954182|gb|ABM11187.1| small multidrug resistance protein [Mycobacterium vanbaalenii
PYR-1]
Length=111
Score = 135 bits (340), Expect = 2e-30, Method: Compositional matrix adjust.
Identities = 70/97 (73%), Positives = 78/97 (81%), Gaps = 0/97 (0%)
Query 9 AIFAEVVATSLLKSTEGFTRLWPTVGCLVGYGIAFALLALSISHGMQTDVAYALWSAIGT 68
AI AEV+ATS+LKSTEGFTRLWPT+ CL+ YG AF LLA SISHGMQ +AYALWSAIGT
Sbjct 12 AILAEVIATSMLKSTEGFTRLWPTLACLLLYGAAFMLLAQSISHGMQVGIAYALWSAIGT 71
Query 69 AAIVLVAVLFLGSPISVMKVVGVGLIVVGVVTLNLAG 105
IV V V FLG PIS +KV+GV L+V GVVTL L G
Sbjct 72 TVIVAVGVTFLGEPISTLKVIGVALVVSGVVTLQLDG 108
>gi|330466683|ref|YP_004404426.1| small multidrug resistance protein [Verrucosispora maris AB-18-032]
gi|328809654|gb|AEB43826.1| small multidrug resistance protein [Verrucosispora maris AB-18-032]
Length=128
Score = 124 bits (310), Expect = 6e-27, Method: Compositional matrix adjust.
Identities = 67/105 (64%), Positives = 80/105 (77%), Gaps = 1/105 (0%)
Query 3 YLYLLCAIFAEVVATSLLKSTEGFTRLWPTVGCLVGYGIAFALLALSISHGMQTDVAYAL 62
Y++LL AI AEV TSLLK+TEGFTRLWPT+G V Y AFALLA ++ G++ VAYAL
Sbjct 25 YVFLLLAIAAEVTGTSLLKATEGFTRLWPTLGLAVSYLTAFALLAQAV-KGIEVGVAYAL 83
Query 63 WSAIGTAAIVLVAVLFLGSPISVMKVVGVGLIVVGVVTLNLAGAH 107
WS +GTAAIV + LG P++V KVVGVGLI+ GVV LNL GAH
Sbjct 84 WSGLGTAAIVAIGATVLGEPLTVTKVVGVGLIIAGVVLLNLRGAH 128
>gi|302866671|ref|YP_003835308.1| small multidrug resistance protein [Micromonospora aurantiaca
ATCC 27029]
gi|315503085|ref|YP_004081972.1| small multidrug resistance protein [Micromonospora sp. L5]
gi|302569530|gb|ADL45732.1| small multidrug resistance protein [Micromonospora aurantiaca
ATCC 27029]
gi|315409704|gb|ADU07821.1| small multidrug resistance protein [Micromonospora sp. L5]
Length=106
Score = 121 bits (303), Expect = 4e-26, Method: Compositional matrix adjust.
Identities = 64/105 (61%), Positives = 79/105 (76%), Gaps = 1/105 (0%)
Query 3 YLYLLCAIFAEVVATSLLKSTEGFTRLWPTVGCLVGYGIAFALLALSISHGMQTDVAYAL 62
YL+LL AI AEV+ TSLLK+T+GFTRLWPTVG V Y AF LL+L++ + VAYA+
Sbjct 3 YLFLLGAITAEVIGTSLLKATDGFTRLWPTVGLAVAYLSAFGLLSLAVKD-IPVGVAYAV 61
Query 63 WSAIGTAAIVLVAVLFLGSPISVMKVVGVGLIVVGVVTLNLAGAH 107
WS +GTAAI+ + FLG P+SV KVVG GL++ GVV LNL GAH
Sbjct 62 WSGLGTAAIMAIGAAFLGEPLSVTKVVGAGLVIAGVVVLNLGGAH 106
>gi|337763591|emb|CCB72301.1| Multidrug resistance protein [Streptomyces cattleya NRRL 8057]
Length=107
Score = 117 bits (292), Expect = 8e-25, Method: Compositional matrix adjust.
Identities = 59/105 (57%), Positives = 72/105 (69%), Gaps = 0/105 (0%)
Query 3 YLYLLCAIFAEVVATSLLKSTEGFTRLWPTVGCLVGYGIAFALLALSISHGMQTDVAYAL 62
YL+LL AI EV TSLLK+T GFTRLWPT CL Y +AF LA +I G+ V YA+
Sbjct 3 YLFLLLAIITEVAGTSLLKATAGFTRLWPTAACLACYAVAFLALARAIGRGLHVGVGYAM 62
Query 63 WSAIGTAAIVLVAVLFLGSPISVMKVVGVGLIVVGVVTLNLAGAH 107
WS +GT IVL+ LFL P++ KV+GV L++ GVV LNL GAH
Sbjct 63 WSGLGTTLIVLIGALFLHEPLTAAKVLGVALVIAGVVVLNLGGAH 107
>gi|302546206|ref|ZP_07298548.1| EmrE protein [Streptomyces hygroscopicus ATCC 53653]
gi|302463824|gb|EFL26917.1| EmrE protein [Streptomyces himastatinicus ATCC 53653]
Length=107
Score = 107 bits (267), Expect = 6e-22, Method: Compositional matrix adjust.
Identities = 56/101 (56%), Positives = 72/101 (72%), Gaps = 0/101 (0%)
Query 3 YLYLLCAIFAEVVATSLLKSTEGFTRLWPTVGCLVGYGIAFALLALSISHGMQTDVAYAL 62
YL LL AI AE++ TSLLKST GF+R P + CL Y +A LLA +I GMQ V YAL
Sbjct 3 YLLLLAAITAELIGTSLLKSTAGFSRPGPALACLASYAVACFLLARAIHDGMQVGVGYAL 62
Query 63 WSAIGTAAIVLVAVLFLGSPISVMKVVGVGLIVVGVVTLNL 103
WS +GTA IV++ +LFLG P++ K +GV L++ GV+TLNL
Sbjct 63 WSGLGTALIVVIGLLFLGEPLTAAKALGVALVIGGVITLNL 103
>gi|239986857|ref|ZP_04707521.1| putative SMR-type multi-drug efflux transporter [Streptomyces
roseosporus NRRL 11379]
gi|291443809|ref|ZP_06583199.1| SMR-type multi-drug efflux transporter [Streptomyces roseosporus
NRRL 15998]
gi|291346756|gb|EFE73660.1| SMR-type multi-drug efflux transporter [Streptomyces roseosporus
NRRL 15998]
Length=108
Score = 105 bits (262), Expect = 2e-21, Method: Compositional matrix adjust.
Identities = 55/105 (53%), Positives = 74/105 (71%), Gaps = 1/105 (0%)
Query 3 YLYLLCAIFAEVVATSLLKSTEGFTRLWPTVGCLVGYGIAFALLALSISHGMQTDVAYAL 62
Y L AI AEV T+ +K +EGFTRLWP++G +VGY IAF LLA ++ + AYA+
Sbjct 5 YGLLAGAIAAEVAGTTAMKYSEGFTRLWPSIGTVVGYLIAFTLLAQTLKT-LSVGTAYAI 63
Query 63 WSAIGTAAIVLVAVLFLGSPISVMKVVGVGLIVVGVVTLNLAGAH 107
W+ +GTAA+ L+ +LFLG S++K+ G+ LIV GVV LNL GAH
Sbjct 64 WAGVGTAAVALIGILFLGESSSLVKIAGIALIVAGVVVLNLGGAH 108
>gi|344998943|ref|YP_004801797.1| small multidrug resistance protein [Streptomyces sp. SirexAA-E]
gi|344314569|gb|AEN09257.1| small multidrug resistance protein [Streptomyces sp. SirexAA-E]
Length=106
Score = 100 bits (248), Expect = 9e-20, Method: Compositional matrix adjust.
Identities = 53/105 (51%), Positives = 73/105 (70%), Gaps = 1/105 (0%)
Query 3 YLYLLCAIFAEVVATSLLKSTEGFTRLWPTVGCLVGYGIAFALLALSISHGMQTDVAYAL 62
Y L AI AEV AT+ +K +EGF+RLWP+V VGY +AFALLA ++ + AYA+
Sbjct 3 YALLAGAIAAEVTATTAMKYSEGFSRLWPSVVTAVGYVLAFALLAQTLKT-LSIGTAYAI 61
Query 63 WSAIGTAAIVLVAVLFLGSPISVMKVVGVGLIVVGVVTLNLAGAH 107
W+ +GTAA+ L+ +L++G P K+VG+ LI+VGVV LNL G H
Sbjct 62 WAGVGTAAVALIGILWMGEPAGAAKLVGLALIIVGVVVLNLGGTH 106
>gi|291440359|ref|ZP_06579749.1| SMR-type multi-drug efflux transporter [Streptomyces ghanaensis
ATCC 14672]
gi|291343254|gb|EFE70210.1| SMR-type multi-drug efflux transporter [Streptomyces ghanaensis
ATCC 14672]
Length=106
Score = 98.2 bits (243), Expect = 4e-19, Method: Compositional matrix adjust.
Identities = 52/105 (50%), Positives = 74/105 (71%), Gaps = 1/105 (0%)
Query 3 YLYLLCAIFAEVVATSLLKSTEGFTRLWPTVGCLVGYGIAFALLALSISHGMQTDVAYAL 62
YL L AI AEV AT+ +K ++GF+RLWP++ L+GY ++FALLA ++ + AYA+
Sbjct 3 YLLLAGAIVAEVCATTAMKYSDGFSRLWPSLLTLLGYVVSFALLAQTLRT-VAVGTAYAI 61
Query 63 WSAIGTAAIVLVAVLFLGSPISVMKVVGVGLIVVGVVTLNLAGAH 107
W+ +GTAAI + VLFLG ++ K G+ LI++GVV LNL GAH
Sbjct 62 WAGVGTAAIATIGVLFLGEGLTAAKAAGIALIIIGVVVLNLGGAH 106
>gi|328881596|emb|CCA54835.1| Ethidium bromide-methyl viologen resistance protein EmrE [Streptomyces
venezuelae ATCC 10712]
Length=112
Score = 97.8 bits (242), Expect = 5e-19, Method: Compositional matrix adjust.
Identities = 53/105 (51%), Positives = 73/105 (70%), Gaps = 1/105 (0%)
Query 3 YLYLLCAIFAEVVATSLLKSTEGFTRLWPTVGCLVGYGIAFALLALSISHGMQTDVAYAL 62
Y L AI AE++AT+ +K +EGF++LWP++ GY IAFALLA ++ +Q AYA+
Sbjct 9 YGLLAGAIAAEILATTSMKYSEGFSKLWPSIITGAGYVIAFALLAQALKT-LQVGTAYAI 67
Query 63 WSAIGTAAIVLVAVLFLGSPISVMKVVGVGLIVVGVVTLNLAGAH 107
WS +GTAA+ + +LFLG +S+ KV G+ LIV GV LNL GAH
Sbjct 68 WSGVGTAAVAAIGILFLGETLSLAKVAGIVLIVAGVAVLNLGGAH 112
>gi|302546313|ref|ZP_07298655.1| multidrug transporter EmrE [Streptomyces hygroscopicus ATCC 53653]
gi|302463931|gb|EFL27024.1| multidrug transporter EmrE [Streptomyces himastatinicus ATCC
53653]
Length=106
Score = 96.7 bits (239), Expect = 9e-19, Method: Compositional matrix adjust.
Identities = 51/105 (49%), Positives = 73/105 (70%), Gaps = 1/105 (0%)
Query 3 YLYLLCAIFAEVVATSLLKSTEGFTRLWPTVGCLVGYGIAFALLALSISHGMQTDVAYAL 62
YL L AI AEV+AT+ +K ++GF++LWP+V +GYGIAF LLA ++ + AYA+
Sbjct 3 YLTLSGAILAEVLATTSMKYSDGFSKLWPSVATALGYGIAFVLLAQTLKT-VSVGTAYAI 61
Query 63 WSAIGTAAIVLVAVLFLGSPISVMKVVGVGLIVVGVVTLNLAGAH 107
W+ GTA I + ++FLG ++ +VVGV L++ GVV LNL GAH
Sbjct 62 WAGAGTAVIAAIGMVFLGEAVTAARVVGVLLVIAGVVVLNLGGAH 106
>gi|302533772|ref|ZP_07286114.1| conserved hypothetical protein [Streptomyces sp. C]
gi|302442667|gb|EFL14483.1| conserved hypothetical protein [Streptomyces sp. C]
Length=113
Score = 96.7 bits (239), Expect = 1e-18, Method: Compositional matrix adjust.
Identities = 51/104 (50%), Positives = 71/104 (69%), Gaps = 1/104 (0%)
Query 3 YLYLLCAIFAEVVATSLLKSTEGFTRLWPTVGCLVGYGIAFALLALSISHGMQTDVAYAL 62
Y+ L AI AEV T+ +K ++GFTRLWP++G LVGY IAF LLA ++ M AYA+
Sbjct 9 YVLLALAIAAEVAGTTAMKYSDGFTRLWPSLGTLVGYVIAFTLLARTLKS-MSVGTAYAI 67
Query 63 WSAIGTAAIVLVAVLFLGSPISVMKVVGVGLIVVGVVTLNLAGA 106
W+ +GTAAI + ++FLG + K+ G+ L++ GVV LNL GA
Sbjct 68 WAGVGTAAIAAIGMVFLGEAATAAKIAGIALVIGGVVLLNLGGA 111
>gi|290961361|ref|YP_003492543.1| protein [Streptomyces scabiei 87.22]
gi|260650887|emb|CBG74004.1| putative integral membrane protein [Streptomyces scabiei 87.22]
Length=106
Score = 95.5 bits (236), Expect = 2e-18, Method: Compositional matrix adjust.
Identities = 53/105 (51%), Positives = 72/105 (69%), Gaps = 1/105 (0%)
Query 3 YLYLLCAIFAEVVATSLLKSTEGFTRLWPTVGCLVGYGIAFALLALSISHGMQTDVAYAL 62
YL L+ AI AEV AT+ +K +EGF++LWP+V VGY ++F LLA ++ M AYA+
Sbjct 3 YLLLVGAIAAEVAATTAMKYSEGFSKLWPSVVTGVGYLVSFVLLAQALKS-MSIGTAYAI 61
Query 63 WSAIGTAAIVLVAVLFLGSPISVMKVVGVGLIVVGVVTLNLAGAH 107
WS +GTAA+ + ++ G +SV KV G+ LIV GVV LNL GAH
Sbjct 62 WSGVGTAAVAALGLMLFGEHLSVAKVAGIVLIVAGVVVLNLGGAH 106
>gi|182439397|ref|YP_001827116.1| putative SMR-type multi-drug efflux transporter [Streptomyces
griseus subsp. griseus NBRC 13350]
gi|326780053|ref|ZP_08239318.1| small multidrug resistance protein [Streptomyces cf. griseus
XylebKG-1]
gi|178467913|dbj|BAG22433.1| putative SMR-type multi-drug efflux transporter [Streptomyces
griseus subsp. griseus NBRC 13350]
gi|326660386|gb|EGE45232.1| small multidrug resistance protein [Streptomyces griseus XylebKG-1]
Length=108
Score = 95.1 bits (235), Expect = 3e-18, Method: Compositional matrix adjust.
Identities = 47/91 (52%), Positives = 66/91 (73%), Gaps = 1/91 (1%)
Query 17 TSLLKSTEGFTRLWPTVGCLVGYGIAFALLALSISHGMQTDVAYALWSAIGTAAIVLVAV 76
T+ +K +EGFTRLWP++G +VGY IAF LLA ++ + AYA+W+ +GTAA+ L+ +
Sbjct 19 TTAMKYSEGFTRLWPSLGTVVGYLIAFTLLAQTLKT-LSVGTAYAIWAGVGTAAVALIGI 77
Query 77 LFLGSPISVMKVVGVGLIVVGVVTLNLAGAH 107
LFLG ++K+ G+ LIV GVV LNL GAH
Sbjct 78 LFLGESSGLVKITGIALIVAGVVVLNLGGAH 108
>gi|331699227|ref|YP_004335466.1| small multidrug resistance protein [Pseudonocardia dioxanivorans
CB1190]
gi|326953916|gb|AEA27613.1| small multidrug resistance protein [Pseudonocardia dioxanivorans
CB1190]
Length=106
Score = 95.1 bits (235), Expect = 3e-18, Method: Compositional matrix adjust.
Identities = 57/105 (55%), Positives = 76/105 (73%), Gaps = 1/105 (0%)
Query 3 YLYLLCAIFAEVVATSLLKSTEGFTRLWPTVGCLVGYGIAFALLALSISHGMQTDVAYAL 62
+L+LL AI EVVAT+ LK ++GF+RL P+V ++GY AF LLA ++ + AYAL
Sbjct 3 WLWLLGAIATEVVATTSLKLSDGFSRLVPSVVVVLGYVGAFVLLAQALKR-FEVGTAYAL 61
Query 63 WSAIGTAAIVLVAVLFLGSPISVMKVVGVGLIVVGVVTLNLAGAH 107
WS IGTAA+VL+ VLFLG +S++K GV LI+ GVV LNL+G H
Sbjct 62 WSGIGTAAVVLIGVLFLGEGLSLVKAGGVLLIIGGVVLLNLSGGH 106
>gi|126650743|ref|ZP_01722959.1| multidrug resistance protein, SMR family [Bacillus sp. B14905]
gi|126592408|gb|EAZ86426.1| multidrug resistance protein, SMR family [Bacillus sp. B14905]
Length=107
Score = 94.0 bits (232), Expect = 6e-18, Method: Compositional matrix adjust.
Identities = 50/106 (48%), Positives = 72/106 (68%), Gaps = 1/106 (0%)
Query 2 IYLYLLCAIFAEVVATSLLKSTEGFTRLWPTVGCLVGYGIAFALLALSISHGMQTDVAYA 61
++ +L AI AEV A+S+LK TEGF+R+WP++G +VGYG AF LAL++ + AYA
Sbjct 3 VFSFLFIAIVAEVFASSMLKRTEGFSRIWPSLGVVVGYGTAFYCLALTLKT-IPIGTAYA 61
Query 62 LWSAIGTAAIVLVAVLFLGSPISVMKVVGVGLIVVGVVTLNLAGAH 107
+W+ +GTA +V V+ + KV+G+ I+VGVV LNLAG H
Sbjct 62 IWAGLGTALTAIVGVVLYKEIFNRKKVLGILCIIVGVVVLNLAGGH 107
>gi|297198855|ref|ZP_06916252.1| multidrug resistance efflux protein [Streptomyces sviceus ATCC
29083]
gi|197711224|gb|EDY55258.1| multidrug resistance efflux protein [Streptomyces sviceus ATCC
29083]
Length=106
Score = 94.0 bits (232), Expect = 7e-18, Method: Compositional matrix adjust.
Identities = 52/105 (50%), Positives = 74/105 (71%), Gaps = 1/105 (0%)
Query 3 YLYLLCAIFAEVVATSLLKSTEGFTRLWPTVGCLVGYGIAFALLALSISHGMQTDVAYAL 62
YL L AI AEV AT+ +K TEGF+RL P++ ++GY ++FALLA ++ + AYA+
Sbjct 3 YLLLAGAIAAEVGATTAMKYTEGFSRLGPSLLTVLGYVLSFALLAQTLKS-VSVGTAYAI 61
Query 63 WSAIGTAAIVLVAVLFLGSPISVMKVVGVGLIVVGVVTLNLAGAH 107
W+ +GTAAIV + ++FLG ++ K G+ LI+VGVV LNL GAH
Sbjct 62 WAGVGTAAIVTIGMVFLGEALTPAKAAGIALIIVGVVVLNLGGAH 106
>gi|169827833|ref|YP_001697991.1| multidrug resistance protein [Lysinibacillus sphaericus C3-41]
gi|168992321|gb|ACA39861.1| Multidrug resistance protein [Lysinibacillus sphaericus C3-41]
Length=107
Score = 93.6 bits (231), Expect = 8e-18, Method: Compositional matrix adjust.
Identities = 49/107 (46%), Positives = 74/107 (70%), Gaps = 1/107 (0%)
Query 1 LIYLYLLCAIFAEVVATSLLKSTEGFTRLWPTVGCLVGYGIAFALLALSISHGMQTDVAY 60
+++ +L AI AEV A+S+LK TEGF+R+WP++G +VGYG AF LAL++ + AY
Sbjct 2 MVFSFLFIAIVAEVFASSMLKRTEGFSRIWPSLGVVVGYGTAFYCLALTLKT-IPIGTAY 60
Query 61 ALWSAIGTAAIVLVAVLFLGSPISVMKVVGVGLIVVGVVTLNLAGAH 107
A+W+ +GTA +V V+ + KV+G+ I++GVV LNLAG+H
Sbjct 61 AIWAGLGTALTAIVGVVLYKELFNRKKVLGILCIILGVVVLNLAGSH 107
>gi|295839577|ref|ZP_06826510.1| multidrug transporter EmrE [Streptomyces sp. SPB74]
gi|197696840|gb|EDY43773.1| multidrug transporter EmrE [Streptomyces sp. SPB74]
Length=106
Score = 92.8 bits (229), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 48/105 (46%), Positives = 72/105 (69%), Gaps = 1/105 (0%)
Query 3 YLYLLCAIFAEVVATSLLKSTEGFTRLWPTVGCLVGYGIAFALLALSISHGMQTDVAYAL 62
YL L AI +EV AT+ +K +EGFTRLWP++ GY + FALLA ++ +Q AYA+
Sbjct 3 YLLLTGAILSEVTATTAMKYSEGFTRLWPSLLTAGGYVVCFALLAQTLKT-LQVGTAYAI 61
Query 63 WSAIGTAAIVLVAVLFLGSPISVMKVVGVGLIVVGVVTLNLAGAH 107
W+ GTA + L+ ++FLG ++ +++ G+ L++ GVV LNL GAH
Sbjct 62 WAGAGTALVALIGMMFLGESVTPVRLAGIALVIGGVVLLNLGGAH 106
>gi|89095990|ref|ZP_01168883.1| multidrug resistance protein [Bacillus sp. NRRL B-14911]
gi|89088844|gb|EAR67952.1| multidrug resistance protein [Bacillus sp. NRRL B-14911]
Length=123
Score = 92.0 bits (227), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 46/102 (46%), Positives = 72/102 (71%), Gaps = 1/102 (0%)
Query 3 YLYLLCAIFAEVVATSLLKSTEGFTRLWPTVGCLVGYGIAFALLALSISHGMQTDVAYAL 62
YL+L AI AE+ TS+LK++EGFT++WP +G L G+G+AF L+LS+ + +AYA+
Sbjct 4 YLFLFIAIAAELFGTSMLKASEGFTKIWPALGVLFGFGVAFFALSLSLKT-IPLSIAYAI 62
Query 63 WSAIGTAAIVLVAVLFLGSPISVMKVVGVGLIVVGVVTLNLA 104
WS IGTAA ++ +L ++++ G+ LI++GVV LN+A
Sbjct 63 WSGIGTAATAVIGILIWKEKLNMLSAAGIILIILGVVLLNMA 104
>gi|302518365|ref|ZP_07270707.1| integral membrane protein [Streptomyces sp. SPB78]
gi|318056390|ref|ZP_07975113.1| SMR-type multi-drug efflux transporter [Streptomyces sp. SA3_actG]
gi|318075709|ref|ZP_07983041.1| SMR-type multi-drug efflux transporter [Streptomyces sp. SA3_actF]
gi|302427260|gb|EFK99075.1| integral membrane protein [Streptomyces sp. SPB78]
Length=106
Score = 92.0 bits (227), Expect = 3e-17, Method: Compositional matrix adjust.
Identities = 48/105 (46%), Positives = 72/105 (69%), Gaps = 1/105 (0%)
Query 3 YLYLLCAIFAEVVATSLLKSTEGFTRLWPTVGCLVGYGIAFALLALSISHGMQTDVAYAL 62
YL L AI +EV AT+ +K +EGFTRLWP++ GY + FALLA ++ ++ AYA+
Sbjct 3 YLLLTGAILSEVTATTAMKYSEGFTRLWPSLLTAGGYVVCFALLAQTLKT-LEVGTAYAI 61
Query 63 WSAIGTAAIVLVAVLFLGSPISVMKVVGVGLIVVGVVTLNLAGAH 107
W+ GTA I L+ ++FLG ++ +++ G+ L++ GVV LNL GAH
Sbjct 62 WAGAGTALIALIGMMFLGESVTPVRLAGIALVIGGVVLLNLGGAH 106
>gi|333027965|ref|ZP_08456029.1| putative SMR-type multi-drug efflux transporter [Streptomyces
sp. Tu6071]
gi|332747817|gb|EGJ78258.1| putative SMR-type multi-drug efflux transporter [Streptomyces
sp. Tu6071]
Length=112
Score = 92.0 bits (227), Expect = 3e-17, Method: Compositional matrix adjust.
Identities = 48/105 (46%), Positives = 72/105 (69%), Gaps = 1/105 (0%)
Query 3 YLYLLCAIFAEVVATSLLKSTEGFTRLWPTVGCLVGYGIAFALLALSISHGMQTDVAYAL 62
YL L AI +EV AT+ +K +EGFTRLWP++ GY + FALLA ++ ++ AYA+
Sbjct 9 YLLLTGAILSEVTATTAMKYSEGFTRLWPSLLTAGGYVVCFALLAQTLKT-LEVGTAYAI 67
Query 63 WSAIGTAAIVLVAVLFLGSPISVMKVVGVGLIVVGVVTLNLAGAH 107
W+ GTA I L+ ++FLG ++ +++ G+ L++ GVV LNL GAH
Sbjct 68 WAGAGTALIALIGMMFLGESVTPVRLAGIALVIGGVVLLNLGGAH 112
>gi|302550605|ref|ZP_07302947.1| multidrug resistance efflux protein [Streptomyces viridochromogenes
DSM 40736]
gi|302468223|gb|EFL31316.1| multidrug resistance efflux protein [Streptomyces viridochromogenes
DSM 40736]
Length=106
Score = 92.0 bits (227), Expect = 3e-17, Method: Compositional matrix adjust.
Identities = 50/105 (48%), Positives = 72/105 (69%), Gaps = 1/105 (0%)
Query 3 YLYLLCAIFAEVVATSLLKSTEGFTRLWPTVGCLVGYGIAFALLALSISHGMQTDVAYAL 62
YL L AI AEV AT+ +K +EGF+RL P+V +GY ++F LLA ++ + AYA+
Sbjct 3 YLLLSAAIAAEVGATTAMKYSEGFSRLGPSVLTFLGYVVSFTLLAQTLKS-VSMGTAYAI 61
Query 63 WSAIGTAAIVLVAVLFLGSPISVMKVVGVGLIVVGVVTLNLAGAH 107
W+ +GTAAI + ++F+G ++V K G+ LI+VGVV LNL GAH
Sbjct 62 WAGVGTAAIATIGMVFMGEGMTVAKAAGLALIIVGVVVLNLGGAH 106
>gi|163841151|ref|YP_001625556.1| quaternary ammonium compound-resistance protein [Renibacterium
salmoninarum ATCC 33209]
gi|162954627|gb|ABY24142.1| quaternary ammonium compound-resistance protein [Renibacterium
salmoninarum ATCC 33209]
Length=92
Score = 91.7 bits (226), Expect = 3e-17, Method: Compositional matrix adjust.
Identities = 45/93 (49%), Positives = 65/93 (70%), Gaps = 1/93 (1%)
Query 15 VATSLLKSTEGFTRLWPTVGCLVGYGIAFALLALSISHGMQTDVAYALWSAIGTAAIVLV 74
+ATSLLK ++GF++LWP+VG +VGY I+F L+L++ + AYA+WS +GTA I ++
Sbjct 1 MATSLLKVSDGFSKLWPSVGVVVGYAISFYALSLALKE-VPVSTAYAIWSGVGTAVIAVI 59
Query 75 AVLFLGSPISVMKVVGVGLIVVGVVTLNLAGAH 107
P+SV K++G+ LIV GVV LNL G H
Sbjct 60 GFWLFKEPLSVTKIIGITLIVAGVVALNLDGGH 92
>gi|302561298|ref|ZP_07313640.1| multidrug transporter EmrE [Streptomyces griseoflavus Tu4000]
gi|302478916|gb|EFL42009.1| multidrug transporter EmrE [Streptomyces griseoflavus Tu4000]
Length=106
Score = 91.7 bits (226), Expect = 3e-17, Method: Compositional matrix adjust.
Identities = 56/105 (54%), Positives = 72/105 (69%), Gaps = 1/105 (0%)
Query 3 YLYLLCAIFAEVVATSLLKSTEGFTRLWPTVGCLVGYGIAFALLALSISHGMQTDVAYAL 62
Y L AI AEVV T+ +K +EGFTRLWP+V VGY +AFALLA ++ M AYA+
Sbjct 3 YALLAGAIAAEVVGTTAMKYSEGFTRLWPSVITAVGYLVAFALLAQTLKT-MSVGTAYAI 61
Query 63 WSAIGTAAIVLVAVLFLGSPISVMKVVGVGLIVVGVVTLNLAGAH 107
WS GTAAI + ++F+G ++ K VG+ LI+VGVV LNL GAH
Sbjct 62 WSGAGTAAIAAIGMMFMGEGLTAAKAVGIALIIVGVVVLNLGGAH 106
>gi|311898957|dbj|BAJ31365.1| putative multidrug resistance protein [Kitasatospora setae KM-6054]
Length=106
Score = 91.3 bits (225), Expect = 4e-17, Method: Compositional matrix adjust.
Identities = 49/107 (46%), Positives = 70/107 (66%), Gaps = 1/107 (0%)
Query 1 LIYLYLLCAIFAEVVATSLLKSTEGFTRLWPTVGCLVGYGIAFALLALSISHGMQTDVAY 60
+ Y+ L AI +EV ATSLLK T+GF+RLWP++ GY ++FALL ++ H + VAY
Sbjct 1 MPYVLLGLAIASEVCATSLLKLTDGFSRLWPSLAVAAGYVLSFALLGRALKH-LPVSVAY 59
Query 61 ALWSAIGTAAIVLVAVLFLGSPISVMKVVGVGLIVVGVVTLNLAGAH 107
A+WS GTAA+ + +F G P+ + G+ L++ GVV LNL AH
Sbjct 60 AVWSGAGTAAVAAIGAVFFGEPLGRPQWCGIVLVIAGVVLLNLRPAH 106
>gi|297161463|gb|ADI11175.1| SMR-type multi-drug efflux transporter [Streptomyces bingchenggensis
BCW-1]
Length=106
Score = 90.9 bits (224), Expect = 5e-17, Method: Compositional matrix adjust.
Identities = 50/105 (48%), Positives = 70/105 (67%), Gaps = 1/105 (0%)
Query 3 YLYLLCAIFAEVVATSLLKSTEGFTRLWPTVGCLVGYGIAFALLALSISHGMQTDVAYAL 62
YL L AI AE++AT+ +K + GF++LWP++ VGY +AFALLA ++ + AYA+
Sbjct 3 YLTLAGAIAAEILATTSMKYSHGFSKLWPSLATAVGYLVAFALLAQTLKT-VSMGTAYAI 61
Query 63 WSAIGTAAIVLVAVLFLGSPISVMKVVGVGLIVVGVVTLNLAGAH 107
W+ GTA I + +LFLG + KV GV L++ GVV LNL GAH
Sbjct 62 WAGAGTAVIAAIGMLFLGEAATAAKVTGVLLVIAGVVVLNLDGAH 106
>gi|329940791|ref|ZP_08290071.1| integral membrane protein [Streptomyces griseoaurantiacus M045]
gi|329300085|gb|EGG43983.1| integral membrane protein [Streptomyces griseoaurantiacus M045]
Length=103
Score = 90.9 bits (224), Expect = 6e-17, Method: Compositional matrix adjust.
Identities = 49/99 (50%), Positives = 67/99 (68%), Gaps = 1/99 (1%)
Query 9 AIFAEVVATSLLKSTEGFTRLWPTVGCLVGYGIAFALLALSISHGMQTDVAYALWSAIGT 68
AI AEV ATS +K +EGFTRLWP+V + GY ++F LLA ++ + AYA+WS +GT
Sbjct 6 AIAAEVAATSAMKYSEGFTRLWPSVLTVAGYLVSFVLLAQTLKT-VSIGSAYAIWSGVGT 64
Query 69 AAIVLVAVLFLGSPISVMKVVGVGLIVVGVVTLNLAGAH 107
AAI ++ +L P++ K+ G+ LIV GVV LN GAH
Sbjct 65 AAIAVIGLLVFDEPLTAAKLAGLALIVAGVVVLNTGGAH 103
>gi|257094493|ref|YP_003168134.1| small multidrug resistance protein [Candidatus Accumulibacter
phosphatis clade IIA str. UW-1]
gi|257047017|gb|ACV36205.1| small multidrug resistance protein [Candidatus Accumulibacter
phosphatis clade IIA str. UW-1]
Length=152
Score = 90.9 bits (224), Expect = 6e-17, Method: Compositional matrix adjust.
Identities = 52/102 (51%), Positives = 68/102 (67%), Gaps = 1/102 (0%)
Query 1 LIYLYLLCAIFAEVVATSLLKSTEGFTRLWPTVGCLVGYGIAFALLALSISHGMQTDVAY 60
L +L L+ AI AEV+AT++LKSTEGFTRLW +V + Y IAF LLAL + + V Y
Sbjct 44 LYWLLLVIAIVAEVIATTMLKSTEGFTRLWSSVIVITCYEIAFILLALCVKR-IAVSVVY 102
Query 61 ALWSAIGTAAIVLVAVLFLGSPISVMKVVGVGLIVVGVVTLN 102
ALWS +G A + LVA +L P+ + GVGLI+ GVV +N
Sbjct 103 ALWSGVGVALVTLVAWFWLDQPLDAAGLAGVGLIIAGVVAIN 144
>gi|134301118|ref|YP_001114614.1| small multidrug resistance protein [Desulfotomaculum reducens
MI-1]
gi|134053818|gb|ABO51789.1| small multidrug resistance protein [Desulfotomaculum reducens
MI-1]
Length=126
Score = 90.5 bits (223), Expect = 7e-17, Method: Compositional matrix adjust.
Identities = 45/103 (44%), Positives = 74/103 (72%), Gaps = 1/103 (0%)
Query 3 YLYLLCAIFAEVVATSLLKSTEGFTRLWPTVGCLVGYGIAFALLALSISHGMQTDVAYAL 62
YLYL+ AI E++ TSLLK++ GF++L+PT+G LV + +AF L+LS+ + ++AYA+
Sbjct 3 YLYLILAILCELIGTSLLKASAGFSKLFPTLGLLVSFSLAFFFLSLSL-KTIPLNLAYAI 61
Query 63 WSAIGTAAIVLVAVLFLGSPISVMKVVGVGLIVVGVVTLNLAG 105
WS +GT A V++++L +++ + G+ LI+VGV+ LNL G
Sbjct 62 WSGLGTIATVIISILIWQERVNIASITGISLIIVGVIILNLYG 104
>gi|54023944|ref|YP_118186.1| putative multi-drug efflux transporter [Nocardia farcinica IFM
10152]
gi|54015452|dbj|BAD56822.1| putative multi-drug efflux transporter [Nocardia farcinica IFM
10152]
Length=107
Score = 90.5 bits (223), Expect = 7e-17, Method: Compositional matrix adjust.
Identities = 47/98 (48%), Positives = 69/98 (71%), Gaps = 0/98 (0%)
Query 10 IFAEVVATSLLKSTEGFTRLWPTVGCLVGYGIAFALLALSISHGMQTDVAYALWSAIGTA 69
I +EV AT LK +EGFT+L P++ +VGY AF L+ ++ GM VAY +WSA+G A
Sbjct 10 IASEVTATVSLKLSEGFTKLTPSIVVVVGYCAAFYFLSQALKRGMAIGVAYGIWSAVGVA 69
Query 70 AIVLVAVLFLGSPISVMKVVGVGLIVVGVVTLNLAGAH 107
AI L+ VLFL +++++V G+GL+++GV+ L L GAH
Sbjct 70 AIALIGVLFLNERLTLVQVGGIGLVILGVLALELGGAH 107
>gi|345014302|ref|YP_004816656.1| small multidrug resistance protein [Streptomyces violaceusniger
Tu 4113]
gi|344040651|gb|AEM86376.1| small multidrug resistance protein [Streptomyces violaceusniger
Tu 4113]
Length=106
Score = 89.7 bits (221), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 50/108 (47%), Positives = 72/108 (67%), Gaps = 7/108 (6%)
Query 3 YLYLLCAIFAEVVATSLLKSTEGFTRLWPTVGCLVGYGIAFALLALSISHGMQT---DVA 59
Y+ L AI AE++AT+ +K +EGF+RLWP++ GY ++F LLA H ++T A
Sbjct 3 YVTLSGAILAEILATTSMKYSEGFSRLWPSLATGAGYLLSFVLLA----HTLKTISVSTA 58
Query 60 YALWSAIGTAAIVLVAVLFLGSPISVMKVVGVGLIVVGVVTLNLAGAH 107
YA+W+ GTA I + +LFLG ++ KV+GV L++ GVV LNL GAH
Sbjct 59 YAIWAGAGTAVIAAIGMLFLGEAMTAAKVLGVLLVIAGVVVLNLNGAH 106
>gi|1848269|gb|AAB47993.1| quaternary ammonium compounds resistance protein Qac [Staphylococcus
aureus]
Length=107
Score = 89.0 bits (219), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 42/104 (41%), Positives = 70/104 (68%), Gaps = 1/104 (0%)
Query 3 YLYLLCAIFAEVVATSLLKSTEGFTRLWPTVGCLVGYGIAFALLALSISHGMQTDVAYAL 62
Y+YLL AI E++ TS LKS EGFT+LWPT+G L+ +GI F L+ ++ + + +++YA
Sbjct 3 YIYLLIAIITEIIGTSFLKSAEGFTKLWPTLGTLISFGICFYFLSTAMKY-LPLNISYAT 61
Query 63 WSAIGTAAIVLVAVLFLGSPISVMKVVGVGLIVVGVVTLNLAGA 106
W+ +G LV+V+ I+++ + + LI++GVV LN+ G+
Sbjct 62 WAGLGLVLTTLVSVIIFKENINLISIFSITLIIIGVVLLNVFGS 105
>gi|88800946|ref|ZP_01116498.1| multidrug resistance protein [Reinekea sp. MED297]
gi|88776321|gb|EAR07544.1| multidrug resistance protein [Reinekea sp. MED297]
Length=109
Score = 89.0 bits (219), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 50/101 (50%), Positives = 69/101 (69%), Gaps = 1/101 (0%)
Query 3 YLYLLCAIFAEVVATSLLKSTEGFTRLWPTVGCLVGYGIAFALLALSISHGMQTDVAYAL 62
+LYLL AI AEV+AT+ LK EGFT+LWP+V ++GY +AF L+L++ + VAYA+
Sbjct 3 WLYLLIAIVAEVIATTSLKPAEGFTKLWPSVVVVIGYAVAFFFLSLTLKT-IPVGVAYAI 61
Query 63 WSAIGTAAIVLVAVLFLGSPISVMKVVGVGLIVVGVVTLNL 103
WS +G A + L++ F G + V+GV LIV GVV LNL
Sbjct 62 WSGLGVALVALLSWWFYGQAFDLAGVIGVCLIVSGVVVLNL 102
>gi|298504825|gb|ADI83548.1| small multidrug resistance family transporter EmrE [Geobacter
sulfurreducens KN400]
Length=110
Score = 88.6 bits (218), Expect = 3e-16, Method: Compositional matrix adjust.
Identities = 49/101 (49%), Positives = 69/101 (69%), Gaps = 1/101 (0%)
Query 3 YLYLLCAIFAEVVATSLLKSTEGFTRLWPTVGCLVGYGIAFALLALSISHGMQTDVAYAL 62
+LYLL AI +EV T+ LKS EGFTRLWP+ +VGY AF L+L++ + +AYA+
Sbjct 4 WLYLLVAIISEVAGTTALKSAEGFTRLWPSCVVVVGYASAFYFLSLTLK-SIPVGIAYAI 62
Query 63 WSAIGTAAIVLVAVLFLGSPISVMKVVGVGLIVVGVVTLNL 103
WS +GTA I +VA +F+G + + V G+ LI+ GV+ LNL
Sbjct 63 WSGLGTALIAVVAWVFMGQRLDLPAVFGILLIIAGVLVLNL 103
>gi|299536851|ref|ZP_07050158.1| multidrug resistance protein [Lysinibacillus fusiformis ZC1]
gi|298727675|gb|EFI68243.1| multidrug resistance protein [Lysinibacillus fusiformis ZC1]
Length=107
Score = 88.6 bits (218), Expect = 3e-16, Method: Compositional matrix adjust.
Identities = 48/105 (46%), Positives = 70/105 (67%), Gaps = 1/105 (0%)
Query 3 YLYLLCAIFAEVVATSLLKSTEGFTRLWPTVGCLVGYGIAFALLALSISHGMQTDVAYAL 62
+ +L AI AEV A+S+LK TEGFTR+ P++G +VGYG AF LAL++ + AYA+
Sbjct 4 FSFLTLAIIAEVFASSMLKRTEGFTRIGPSIGVVVGYGTAFYCLALTLKV-IPIGTAYAI 62
Query 63 WSAIGTAAIVLVAVLFLGSPISVMKVVGVGLIVVGVVTLNLAGAH 107
W+ +GTA +V V+ + K++G+ I++GVV LNLAG H
Sbjct 63 WAGLGTALTAIVGVVLYKERFNRKKILGILCIILGVVVLNLAGGH 107
>gi|34498135|ref|NP_902350.1| quaternary ammonium compound resistance protein / ethidium bromide
resistant protein [Chromobacterium violaceum ATCC 12472]
gi|34103990|gb|AAQ60350.1| quaternary ammonium compound resistance protein / ethidium bromide
resistant protein [Chromobacterium violaceum ATCC 12472]
Length=110
Score = 87.8 bits (216), Expect = 5e-16, Method: Compositional matrix adjust.
Identities = 47/102 (47%), Positives = 70/102 (69%), Gaps = 1/102 (0%)
Query 2 IYLYLLCAIFAEVVATSLLKSTEGFTRLWPTVGCLVGYGIAFALLALSISHGMQTDVAYA 61
++L+L+ AI +EVVATS LK+++GFTRLWP++ GY +AF LL+ ++ H + +AYA
Sbjct 3 VWLFLMGAILSEVVATSALKASDGFTRLWPSLLTAGGYVLAFYLLSQTLRH-IPVGIAYA 61
Query 62 LWSAIGTAAIVLVAVLFLGSPISVMKVVGVGLIVVGVVTLNL 103
LWS IG + L+A L G + + V G+GLI+ GV +NL
Sbjct 62 LWSGIGIVLVSLIAWLLYGQKLDLAAVAGMGLIIAGVAVINL 103
>gi|300716358|ref|YP_003741161.1| hypothetical protein EbC_17790 [Erwinia billingiae Eb661]
gi|299062194|emb|CAX59310.1| putative membrane protein [Erwinia billingiae Eb661]
Length=111
Score = 87.4 bits (215), Expect = 6e-16, Method: Compositional matrix adjust.
Identities = 46/101 (46%), Positives = 68/101 (68%), Gaps = 1/101 (0%)
Query 3 YLYLLCAIFAEVVATSLLKSTEGFTRLWPTVGCLVGYGIAFALLALSISHGMQTDVAYAL 62
Y++L AI AEV+ATS LKS+E FTRLWPTV C++GY +AF L+L++ + T +AYA+
Sbjct 5 YMFLGIAIIAEVIATSSLKSSESFTRLWPTVLCVLGYTVAFFFLSLTL-KALPTGIAYAI 63
Query 63 WSAIGTAAIVLVAVLFLGSPISVMKVVGVGLIVVGVVTLNL 103
WS +G I + + L G + + G+ LI+ GV+ +NL
Sbjct 64 WSGVGIVLISVTSYLLYGQKLDPAGIAGLTLIIAGVLVVNL 104
>gi|337750354|ref|YP_004644516.1| multidrug resistance protein [Paenibacillus mucilaginosus KNP414]
gi|336301543|gb|AEI44646.1| multidrug resistance protein [Paenibacillus mucilaginosus KNP414]
Length=108
Score = 86.7 bits (213), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 50/106 (48%), Positives = 70/106 (67%), Gaps = 2/106 (1%)
Query 3 YLYLLCAIFAEVVATSLLKSTEGFTRLWPTVGCLVGYGIAFALLALSISHGMQTDVAYAL 62
YL+L AI E+ TS+LK++ GFT+LWP++G L+G+GIAF L+LS+ + VAYA+
Sbjct 4 YLFLALAIVTELFGTSMLKASAGFTKLWPSLGVLMGFGIAFYSLSLSL-QSIPLSVAYAI 62
Query 63 WSAIGTAAIVLVAVLFLGSPISVMKVVGVGLIVVGVVTLNLAG-AH 107
WS +GTA + VL IS+ G+ LI+ GVV +NL G AH
Sbjct 63 WSGVGTALTAAIGVLIWKESISLPTAGGILLIIAGVVLINLKGPAH 108
Lambda K H
0.329 0.141 0.422
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 130484177216
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
Posted date: Sep 5, 2011 4:36 AM
Number of letters in database: 5,219,829,388
Number of sequences in database: 15,229,318
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40