BLASTP 2.2.25+
Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
15,229,318 sequences; 5,219,829,388 total letters
Query= Rv3066
Length=202
Score E
Sequences producing significant alignments: (Bits) Value
gi|15610203|ref|NP_217582.1| DeoR family transcriptional regulat... 394 3e-108
gi|240170695|ref|ZP_04749354.1| transcriptional regulatory prote... 256 1e-66
gi|118618738|ref|YP_907070.1| transcriptional regulatory protein... 248 3e-64
gi|259090351|pdb|3IUV|A Chain A, The Structure Of A Member Of Te... 112 4e-23
gi|337763592|emb|CCB72302.1| Transcriptional regulatory protein ... 111 5e-23
gi|291440360|ref|ZP_06579750.1| TetR-family transcriptional regu... 111 6e-23
gi|21220404|ref|NP_626183.1| hypothetical protein SCO1917 [Strep... 111 6e-23
gi|300508406|pdb|3HTA|A Chain A, Crystal Structure Of Multidrug ... 111 6e-23
gi|297198854|ref|ZP_06916251.1| ebrA repressor [Streptomyces svi... 108 3e-22
gi|300789381|ref|YP_003769672.1| TetR family transcriptional reg... 107 1e-21
gi|302533771|ref|ZP_07286113.1| ebrA repressor [Streptomyces sp.... 105 5e-21
gi|294628707|ref|ZP_06707267.1| transcriptional regulatory prote... 103 1e-20
gi|302550604|ref|ZP_07302946.1| TetR family transcriptional regu... 102 2e-20
gi|290961362|ref|YP_003492544.1| repressor [Streptomyces scabiei... 100 9e-20
gi|29832878|ref|NP_827512.1| TetR family transcriptional regulat... 99.4 3e-19
gi|320011459|gb|ADW06309.1| transcriptional regulator, TetR fami... 98.2 6e-19
gi|302546314|ref|ZP_07298656.1| TetR family transcriptional regu... 97.4 1e-18
gi|294632913|ref|ZP_06711472.1| conserved hypothetical protein [... 96.7 2e-18
gi|326780054|ref|ZP_08239319.1| transcriptional regulator, TetR ... 95.9 3e-18
gi|344998942|ref|YP_004801796.1| TetR family transcriptional reg... 94.0 1e-17
gi|328881595|emb|CCA54834.1| Transcriptional regulator, TetR fam... 93.6 1e-17
gi|262201944|ref|YP_003273152.1| TetR family transcriptional reg... 91.3 7e-17
gi|182439398|ref|YP_001827117.1| TetR family transcriptional reg... 90.9 1e-16
gi|254384161|ref|ZP_04999505.1| ebrA repressor [Streptomyces sp.... 88.2 6e-16
gi|257057139|ref|YP_003134971.1| hypothetical protein Svir_31710... 88.2 6e-16
gi|269219739|ref|ZP_06163593.1| putative transcriptional regulat... 87.8 8e-16
gi|296137890|ref|YP_003645133.1| TetR family transcriptional reg... 87.4 1e-15
gi|326383954|ref|ZP_08205638.1| regulatory protein TetR [Gordoni... 86.7 2e-15
gi|333920137|ref|YP_004493718.1| hypothetical protein AS9A_2471 ... 85.9 3e-15
gi|295839578|ref|ZP_06826511.1| TetR family transcriptional regu... 84.3 8e-15
gi|318056391|ref|ZP_07975114.1| hypothetical protein SSA3_00505 ... 83.2 2e-14
gi|311280270|ref|YP_003942501.1| transcriptional regulator, TetR... 83.2 2e-14
gi|302518364|ref|ZP_07270706.1| ebrA repressor [Streptomyces sp.... 82.8 3e-14
gi|333027966|ref|ZP_08456030.1| hypothetical protein STTU_5470 [... 82.0 4e-14
gi|260597241|ref|YP_003209812.1| HTH-type transcriptional regula... 82.0 5e-14
gi|157146502|ref|YP_001453820.1| hypothetical protein CKO_02263 ... 81.6 6e-14
gi|271969071|ref|YP_003343267.1| TetR family transcriptional reg... 80.9 9e-14
gi|146310995|ref|YP_001176069.1| TetR family transcriptional reg... 80.5 1e-13
gi|239986856|ref|ZP_04707520.1| TetR family transcriptional regu... 80.5 1e-13
gi|134103635|ref|YP_001109296.1| putative DeoR-type transcriptio... 80.5 1e-13
gi|170768984|ref|ZP_02903437.1| transcriptional regulator, TetR ... 79.3 3e-13
gi|297560633|ref|YP_003679607.1| TetR family transcriptional reg... 79.3 3e-13
gi|257057801|ref|YP_003135633.1| hypothetical protein Svir_38620... 78.2 7e-13
gi|302531180|ref|ZP_07283522.1| predicted protein [Streptomyces ... 77.8 8e-13
gi|283784609|ref|YP_003364474.1| TetR family transcriptional reg... 77.8 8e-13
gi|336249446|ref|YP_004593156.1| putative DeoR-type transcriptio... 77.8 9e-13
gi|324112718|gb|EGC06694.1| tetR family protein regulatory prote... 77.8 9e-13
gi|134101872|ref|YP_001107533.1| TetR family transcriptional reg... 77.4 1e-12
gi|333955922|gb|EGL73629.1| hypothetical protein CSE899_05067 [C... 77.4 1e-12
gi|345014301|ref|YP_004816655.1| TetR family transcriptional reg... 77.4 1e-12
>gi|15610203|ref|NP_217582.1| DeoR family transcriptional regulator [Mycobacterium tuberculosis
H37Rv]
gi|15842635|ref|NP_337672.1| hypothetical protein MT3151 [Mycobacterium tuberculosis CDC1551]
gi|31794245|ref|NP_856738.1| DeoR family transcriptional regulator [Mycobacterium bovis AF2122/97]
78 more sequence titles
gi|121638951|ref|YP_979175.1| DeoR family transcriptional regulator [Mycobacterium bovis BCG
str. Pasteur 1173P2]
gi|148662920|ref|YP_001284443.1| DeoR family transcriptional regulator [Mycobacterium tuberculosis
H37Ra]
gi|148824258|ref|YP_001289012.1| DeoR family transcriptional regulator [Mycobacterium tuberculosis
F11]
gi|167969669|ref|ZP_02551946.1| hypothetical transcriptional regulatory protein, deoR-family
[Mycobacterium tuberculosis H37Ra]
gi|224991443|ref|YP_002646132.1| putative transcriptional regulatory protein [Mycobacterium bovis
BCG str. Tokyo 172]
gi|253797834|ref|YP_003030835.1| transcriptional regulator, deoR-family [Mycobacterium tuberculosis
KZN 1435]
gi|254365695|ref|ZP_04981740.1| hypothetical transcriptional regulatory protein (probably deoR-family)
[Mycobacterium tuberculosis str. Haarlem]
gi|254552142|ref|ZP_05142589.1| transcriptional regulator, deoR-family protein [Mycobacterium
tuberculosis '98-R604 INH-RIF-EM']
gi|289444629|ref|ZP_06434373.1| transcriptional regulator, deoR-family [Mycobacterium tuberculosis
T46]
gi|289448745|ref|ZP_06438489.1| transcriptional regulator, deoR-family [Mycobacterium tuberculosis
CPHL_A]
gi|289553143|ref|ZP_06442353.1| transcriptional regulator, deoR-family [Mycobacterium tuberculosis
KZN 605]
gi|289571272|ref|ZP_06451499.1| transcriptional regulator, deoR-family [Mycobacterium tuberculosis
T17]
gi|289575777|ref|ZP_06456004.1| transcriptional regulator, deoR-family [Mycobacterium tuberculosis
K85]
gi|289746875|ref|ZP_06506253.1| DeoR family transcriptional regulator [Mycobacterium tuberculosis
02_1987]
gi|289751740|ref|ZP_06511118.1| transcriptional regulator, deoR-family [Mycobacterium tuberculosis
T92]
gi|289755183|ref|ZP_06514561.1| deor-family transcriptional regulator [Mycobacterium tuberculosis
EAS054]
gi|289759191|ref|ZP_06518569.1| DeoR family transcriptional regulator [Mycobacterium tuberculosis
T85]
gi|289763245|ref|ZP_06522623.1| deor-family transcriptional regulator [Mycobacterium tuberculosis
GM 1503]
gi|294993430|ref|ZP_06799121.1| transcriptional regulator, deoR-family protein [Mycobacterium
tuberculosis 210]
gi|297635699|ref|ZP_06953479.1| transcriptional regulator, deoR-family protein [Mycobacterium
tuberculosis KZN 4207]
gi|297732697|ref|ZP_06961815.1| transcriptional regulator, deoR-family protein [Mycobacterium
tuberculosis KZN R506]
gi|298526538|ref|ZP_07013947.1| hypothetical transcriptional regulatory protein, deoR-family
[Mycobacterium tuberculosis 94_M4241A]
gi|306777373|ref|ZP_07415710.1| transcriptional regulator, deoR-family [Mycobacterium tuberculosis
SUMu001]
gi|306781277|ref|ZP_07419614.1| transcriptional regulator, deoR-family [Mycobacterium tuberculosis
SUMu002]
gi|306785918|ref|ZP_07424240.1| transcriptional regulator, deoR-family [Mycobacterium tuberculosis
SUMu003]
gi|306790272|ref|ZP_07428594.1| transcriptional regulator, deoR-family [Mycobacterium tuberculosis
SUMu004]
gi|306794767|ref|ZP_07433069.1| transcriptional regulator, deoR-family [Mycobacterium tuberculosis
SUMu005]
gi|306799009|ref|ZP_07437311.1| transcriptional regulator, deoR-family [Mycobacterium tuberculosis
SUMu006]
gi|306804852|ref|ZP_07441520.1| transcriptional regulator, deoR-family [Mycobacterium tuberculosis
SUMu008]
gi|306809045|ref|ZP_07445713.1| transcriptional regulator, deoR-family [Mycobacterium tuberculosis
SUMu007]
gi|306969145|ref|ZP_07481806.1| transcriptional regulator, deoR-family [Mycobacterium tuberculosis
SUMu009]
gi|306973489|ref|ZP_07486150.1| transcriptional regulator, deoR-family [Mycobacterium tuberculosis
SUMu010]
gi|307081199|ref|ZP_07490369.1| transcriptional regulator, deoR-family [Mycobacterium tuberculosis
SUMu011]
gi|307085798|ref|ZP_07494911.1| transcriptional regulator, deoR-family [Mycobacterium tuberculosis
SUMu012]
gi|313660029|ref|ZP_07816909.1| transcriptional regulator, deoR-family protein [Mycobacterium
tuberculosis KZN V2475]
gi|339633074|ref|YP_004724716.1| transcriptional regulator (probably DEOR-family) [Mycobacterium
africanum GM041182]
gi|340628057|ref|YP_004746509.1| putative transcriptional regulatory protein [Mycobacterium canettii
CIPT 140010059]
gi|1781147|emb|CAB06257.1| PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY DEOR-FAMILY)
[Mycobacterium tuberculosis H37Rv]
gi|13882951|gb|AAK47486.1| conserved hypothetical protein [Mycobacterium tuberculosis CDC1551]
gi|31619840|emb|CAD96780.1| PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY DEOR-FAMILY)
[Mycobacterium bovis AF2122/97]
gi|121494599|emb|CAL73080.1| Probable transcriptional regulatory protein (probably deoR-family)
[Mycobacterium bovis BCG str. Pasteur 1173P2]
gi|134151208|gb|EBA43253.1| hypothetical transcriptional regulatory protein (probably deoR-family)
[Mycobacterium tuberculosis str. Haarlem]
gi|148507072|gb|ABQ74881.1| Deor-family transcriptional regulator [Mycobacterium tuberculosis
H37Ra]
gi|148722785|gb|ABR07410.1| hypothetical transcriptional regulatory protein, deoR-family
[Mycobacterium tuberculosis F11]
gi|224774558|dbj|BAH27364.1| putative transcriptional regulatory protein [Mycobacterium bovis
BCG str. Tokyo 172]
gi|253319337|gb|ACT23940.1| transcriptional regulator, deoR-family [Mycobacterium tuberculosis
KZN 1435]
gi|289417548|gb|EFD14788.1| transcriptional regulator, deoR-family [Mycobacterium tuberculosis
T46]
gi|289421703|gb|EFD18904.1| transcriptional regulator, deoR-family [Mycobacterium tuberculosis
CPHL_A]
gi|289437775|gb|EFD20268.1| transcriptional regulator, deoR-family [Mycobacterium tuberculosis
KZN 605]
gi|289540208|gb|EFD44786.1| transcriptional regulator, deoR-family [Mycobacterium tuberculosis
K85]
gi|289545026|gb|EFD48674.1| transcriptional regulator, deoR-family [Mycobacterium tuberculosis
T17]
gi|289687403|gb|EFD54891.1| DeoR family transcriptional regulator [Mycobacterium tuberculosis
02_1987]
gi|289692327|gb|EFD59756.1| transcriptional regulator, deoR-family [Mycobacterium tuberculosis
T92]
gi|289695770|gb|EFD63199.1| deor-family transcriptional regulator [Mycobacterium tuberculosis
EAS054]
gi|289710751|gb|EFD74767.1| deor-family transcriptional regulator [Mycobacterium tuberculosis
GM 1503]
gi|289714755|gb|EFD78767.1| DeoR family transcriptional regulator [Mycobacterium tuberculosis
T85]
gi|298496332|gb|EFI31626.1| hypothetical transcriptional regulatory protein, deoR-family
[Mycobacterium tuberculosis 94_M4241A]
gi|308214264|gb|EFO73663.1| transcriptional regulator, deoR-family [Mycobacterium tuberculosis
SUMu001]
gi|308325919|gb|EFP14770.1| transcriptional regulator, deoR-family [Mycobacterium tuberculosis
SUMu002]
gi|308329441|gb|EFP18292.1| transcriptional regulator, deoR-family [Mycobacterium tuberculosis
SUMu003]
gi|308333286|gb|EFP22137.1| transcriptional regulator, deoR-family [Mycobacterium tuberculosis
SUMu004]
gi|308336941|gb|EFP25792.1| transcriptional regulator, deoR-family [Mycobacterium tuberculosis
SUMu005]
gi|308340757|gb|EFP29608.1| transcriptional regulator, deoR-family [Mycobacterium tuberculosis
SUMu006]
gi|308344624|gb|EFP33475.1| transcriptional regulator, deoR-family [Mycobacterium tuberculosis
SUMu007]
gi|308348572|gb|EFP37423.1| transcriptional regulator, deoR-family [Mycobacterium tuberculosis
SUMu008]
gi|308353298|gb|EFP42149.1| transcriptional regulator, deoR-family [Mycobacterium tuberculosis
SUMu009]
gi|308357131|gb|EFP45982.1| transcriptional regulator, deoR-family [Mycobacterium tuberculosis
SUMu010]
gi|308361083|gb|EFP49934.1| transcriptional regulator, deoR-family [Mycobacterium tuberculosis
SUMu011]
gi|308364718|gb|EFP53569.1| transcriptional regulator, deoR-family [Mycobacterium tuberculosis
SUMu012]
gi|323718298|gb|EGB27476.1| transcriptional regulator [Mycobacterium tuberculosis CDC1551A]
gi|326902712|gb|EGE49645.1| transcriptional regulator, deoR-family [Mycobacterium tuberculosis
W-148]
gi|328457613|gb|AEB03036.1| transcriptional regulator, deoR-family [Mycobacterium tuberculosis
KZN 4207]
gi|339295901|gb|AEJ48012.1| DeoR family transcriptional regulator [Mycobacterium tuberculosis
CCDC5079]
gi|339299514|gb|AEJ51624.1| DeoR family transcriptional regulator [Mycobacterium tuberculosis
CCDC5180]
gi|339332430|emb|CCC28143.1| putative transcriptional regulatory protein (probably DEOR-family)
[Mycobacterium africanum GM041182]
gi|340006247|emb|CCC45422.1| putative transcriptional regulatory protein (probably DEOR-family)
[Mycobacterium canettii CIPT 140010059]
gi|341602990|emb|CCC65668.1| probable transcriptional regulatory protein (probably deoR-family)
[Mycobacterium bovis BCG str. Moreau RDJ]
gi|344220902|gb|AEN01533.1| DeoR family transcriptional regulator [Mycobacterium tuberculosis
CTRI-2]
Length=202
Score = 394 bits (1013), Expect = 3e-108, Method: Compositional matrix adjust.
Identities = 201/202 (99%), Positives = 202/202 (100%), Gaps = 0/202 (0%)
Query 1 LTAGSDRRPRDPAGRRQAIVEAAERVIARQGLGGLSHRRVAAEANVPVGSTTYYFNDLDA 60
+TAGSDRRPRDPAGRRQAIVEAAERVIARQGLGGLSHRRVAAEANVPVGSTTYYFNDLDA
Sbjct 1 MTAGSDRRPRDPAGRRQAIVEAAERVIARQGLGGLSHRRVAAEANVPVGSTTYYFNDLDA 60
Query 61 LREAALAHAANASADLLAQWRSDLDKDRDLAATLARLTTVYLADQDRYRTLNELYMAAAH 120
LREAALAHAANASADLLAQWRSDLDKDRDLAATLARLTTVYLADQDRYRTLNELYMAAAH
Sbjct 61 LREAALAHAANASADLLAQWRSDLDKDRDLAATLARLTTVYLADQDRYRTLNELYMAAAH 120
Query 121 RPELQRLARLWPDGLLALLEPRIGRRAANAVTVFFDGATLHALITGTPLSTDELTDAIAR 180
RPELQRLARLWPDGLLALLEPRIGRRAANAVTVFFDGATLHALITGTPLSTDELTDAIAR
Sbjct 121 RPELQRLARLWPDGLLALLEPRIGRRAANAVTVFFDGATLHALITGTPLSTDELTDAIAR 180
Query 181 LVADGPEQREVGQSAHAGRTPD 202
LVADGPEQREVGQSAHAGRTPD
Sbjct 181 LVADGPEQREVGQSAHAGRTPD 202
>gi|240170695|ref|ZP_04749354.1| transcriptional regulatory protein [Mycobacterium kansasii ATCC
12478]
Length=185
Score = 256 bits (654), Expect = 1e-66, Method: Compositional matrix adjust.
Identities = 139/184 (76%), Positives = 157/184 (86%), Gaps = 0/184 (0%)
Query 1 LTAGSDRRPRDPAGRRQAIVEAAERVIARQGLGGLSHRRVAAEANVPVGSTTYYFNDLDA 60
+TA RRPRDP GRRQAI+EAA RVIAR GLG L+HRRVAAEA+VPVGSTTYYF+DL
Sbjct 1 MTAEPHRRPRDPVGRRQAIIEAAGRVIARHGLGELTHRRVAAEADVPVGSTTYYFSDLGT 60
Query 61 LREAALAHAANASADLLAQWRSDLDKDRDLAATLARLTTVYLADQDRYRTLNELYMAAAH 120
LREAALAHAA ++AD L QWR DLD+ DL TLARLT YL D DR+RTL+ELY+AA+H
Sbjct 61 LREAALAHAATSAADWLEQWRRDLDRAADLPVTLARLTAEYLTDPDRHRTLSELYVAASH 120
Query 121 RPELQRLARLWPDGLLALLEPRIGRRAANAVTVFFDGATLHALITGTPLSTDELTDAIAR 180
RPELQ LARLWP+GL+ALLEPRIGRRAA AVTVF DGAT+H+LITGTPLS + LTDA+AR
Sbjct 121 RPELQSLARLWPEGLVALLEPRIGRRAAEAVTVFLDGATVHSLITGTPLSVEALTDAVAR 180
Query 181 LVAD 184
L AD
Sbjct 181 LAAD 184
>gi|118618738|ref|YP_907070.1| transcriptional regulatory protein [Mycobacterium ulcerans Agy99]
gi|183981626|ref|YP_001849917.1| transcriptional regulatory protein [Mycobacterium marinum M]
gi|118570848|gb|ABL05599.1| transcriptional regulatory protein [Mycobacterium ulcerans Agy99]
gi|183174952|gb|ACC40062.1| transcriptional regulatory protein [Mycobacterium marinum M]
Length=192
Score = 248 bits (634), Expect = 3e-64, Method: Compositional matrix adjust.
Identities = 126/184 (69%), Positives = 148/184 (81%), Gaps = 0/184 (0%)
Query 1 LTAGSDRRPRDPAGRRQAIVEAAERVIARQGLGGLSHRRVAAEANVPVGSTTYYFNDLDA 60
+T +RRPRDPAGRRQ I+EAA R+IAR GLG L+HRRVAAEA+VPVGSTTYYF+DL
Sbjct 1 MTREVERRPRDPAGRRQTIIEAAGRLIARHGLGDLTHRRVAAEADVPVGSTTYYFSDLGE 60
Query 61 LREAALAHAANASADLLAQWRSDLDKDRDLAATLARLTTVYLADQDRYRTLNELYMAAAH 120
LREAALAH A ++ D L W DLD+ D+ ATLARLT YL D DR+RTLNELY+AA+H
Sbjct 61 LREAALAHVATSATDWLEHWERDLDESTDIPATLARLTADYLTDPDRHRTLNELYVAASH 120
Query 121 RPELQRLARLWPDGLLALLEPRIGRRAANAVTVFFDGATLHALITGTPLSTDELTDAIAR 180
+PELQ LA+LW DGL+ALLEPRIG RAA V++F DGATLHA+I+ TPL LTDAIAR
Sbjct 121 QPELQSLAQLWSDGLVALLEPRIGPRAARVVSIFLDGATLHAMISDTPLDAPALTDAIAR 180
Query 181 LVAD 184
LV +
Sbjct 181 LVGN 184
>gi|259090351|pdb|3IUV|A Chain A, The Structure Of A Member Of Tetr Family (Sco1917) From
Streptomyces Coelicolor A3
Length=201
Score = 112 bits (279), Expect = 4e-23, Method: Compositional matrix adjust.
Identities = 74/180 (42%), Positives = 102/180 (57%), Gaps = 2/180 (1%)
Query 4 GSDRRPRDPAGRRQAIVEAAERVIARQGLGGLSHRRVAAEANVPVGSTTYYFNDLDALRE 63
G R DP RRQ I++AA RV+ ++G+ GLSHR VAAEA+VP+GSTTY+F LD L
Sbjct 1 GHXPRRHDPE-RRQRIIDAAIRVVGQKGIAGLSHRTVAAEADVPLGSTTYHFATLDDLXV 59
Query 64 AALAHAANASADLLAQWRSDLDKDRDLAATLARLTTVYL-ADQDRYRTLNELYMAAAHRP 122
AAL A A ++A + D + DL+ LAR+ +L D+ ELY+AA RP
Sbjct 60 AALRQANEGFARVVAAHPALSDPEADLSGELARVLGEWLGGDRTGVELEYELYLAALRRP 119
Query 123 ELQRLARLWPDGLLALLEPRIGRRAANAVTVFFDGATLHALITGTPLSTDELTDAIARLV 182
L+ +A W +G+ ALL R A A+ DG L L+T TP + + + RL+
Sbjct 120 ALRPVAAEWAEGVGALLAARTDPTTARALVAVLDGICLQVLLTDTPYDEEYAREVLTRLI 179
>gi|337763592|emb|CCB72302.1| Transcriptional regulatory protein [Streptomyces cattleya NRRL
8057]
Length=194
Score = 111 bits (278), Expect = 5e-23, Method: Compositional matrix adjust.
Identities = 82/170 (49%), Positives = 97/170 (58%), Gaps = 0/170 (0%)
Query 18 AIVEAAERVIARQGLGGLSHRRVAAEANVPVGSTTYYFNDLDALREAALAHAANASADLL 77
AIVEAA +I G+ GLSHR VAA A VP+G+TTYYF DL L AAL HAA + L
Sbjct 20 AIVEAACALIPDTGIHGLSHRLVAARAGVPLGATTYYFTDLADLSRAALEHAAARWTEEL 79
Query 78 AQWRSDLDKDRDLAATLARLTTVYLADQDRYRTLNELYMAAAHRPELQRLARLWPDGLLA 137
W + L D+ A LA L Y D+ R ELY AAA RPEL+ LA LW DGL+
Sbjct 80 RAWATALRDSDDVPAALAALAARYAEDRPRALIEAELYTAAARRPELRPLAHLWFDGLVR 139
Query 138 LLEPRIGRRAANAVTVFFDGATLHALITGTPLSTDELTDAIARLVADGPE 187
+L AA A + DGA L AL P+ ELT A+ L+ DGPE
Sbjct 140 VLRAHTTPAAATATALLLDGALLRALRDEDPVDVTELTAALRTLMGDGPE 189
>gi|291440360|ref|ZP_06579750.1| TetR-family transcriptional regulator [Streptomyces ghanaensis
ATCC 14672]
gi|291343255|gb|EFE70211.1| TetR-family transcriptional regulator [Streptomyces ghanaensis
ATCC 14672]
Length=181
Score = 111 bits (278), Expect = 6e-23, Method: Compositional matrix adjust.
Identities = 75/176 (43%), Positives = 98/176 (56%), Gaps = 2/176 (1%)
Query 8 RPRDPAGRRQAIVEAAERVIARQGLGGLSHRRVAAEANVPVGSTTYYFNDLDALREAALA 67
R DP RRQ I++AA RV+ R G+ GLSHR AAEA+VP+GSTTY+F LD L AAL
Sbjct 4 RRHDPE-RRQRIIDAAIRVVGRGGIAGLSHRSAAAEADVPLGSTTYHFKTLDELLVAALR 62
Query 68 HAANASADLLAQWRSDLDKDRDLAATLARLTTVYLADQDRYRTLN-ELYMAAAHRPELQR 126
A +A R+ +D DLAA LA L +LA + L ELY+AA RP L+
Sbjct 63 QTNEGFAKAVAARRTLMDPRTDLAAELAALIGEWLAGERTGVELEYELYLAALRRPALRP 122
Query 127 LARLWPDGLLALLEPRIGRRAANAVTVFFDGATLHALITGTPLSTDELTDAIARLV 182
+A W + + LL R A A+ DG L L+TG P + + +AR+V
Sbjct 123 VAAEWCEEVTELLSRRTDPVTARALVALMDGICLQVLLTGGPYDEEYAREMMARIV 178
>gi|21220404|ref|NP_626183.1| hypothetical protein SCO1917 [Streptomyces coelicolor A3(2)]
gi|289772362|ref|ZP_06531740.1| ebrA repressor [Streptomyces lividans TK24]
gi|5420026|emb|CAB46418.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)]
gi|16604268|gb|AAK95485.1| ebrA repressor [Streptomyces lividans]
gi|289702561|gb|EFD69990.1| ebrA repressor [Streptomyces lividans TK24]
Length=197
Score = 111 bits (278), Expect = 6e-23, Method: Compositional matrix adjust.
Identities = 70/169 (42%), Positives = 98/169 (58%), Gaps = 1/169 (0%)
Query 15 RRQAIVEAAERVIARQGLGGLSHRRVAAEANVPVGSTTYYFNDLDALREAALAHAANASA 74
RRQ I++AA RV+ ++G+ GLSHR VAAEA+VP+GSTTY+F LD L AAL A A
Sbjct 9 RRQRIIDAAIRVVGQKGIAGLSHRTVAAEADVPLGSTTYHFATLDDLMVAALRQANEGFA 68
Query 75 DLLAQWRSDLDKDRDLAATLARLTTVYL-ADQDRYRTLNELYMAAAHRPELQRLARLWPD 133
++A + D + DL+ LAR+ +L D+ ELY+AA RP L+ +A W +
Sbjct 69 RVVAAHPALSDPEADLSGELARVLGEWLGGDRTGVELEYELYLAALRRPALRPVAAEWAE 128
Query 134 GLLALLEPRIGRRAANAVTVFFDGATLHALITGTPLSTDELTDAIARLV 182
G+ ALL R A A+ DG L L+T TP + + + RL+
Sbjct 129 GVGALLAARTDPTTARALVAVLDGICLQVLLTDTPYDEEYAREVLTRLI 177
>gi|300508406|pdb|3HTA|A Chain A, Crystal Structure Of Multidrug Binding Protein Ebrr
Complexed With Imidazole
gi|300508407|pdb|3HTA|B Chain B, Crystal Structure Of Multidrug Binding Protein Ebrr
Complexed With Imidazole
gi|300508408|pdb|3HTA|C Chain C, Crystal Structure Of Multidrug Binding Protein Ebrr
Complexed With Imidazole
7 more sequence titles
Length=217
Score = 111 bits (277), Expect = 6e-23, Method: Compositional matrix adjust.
Identities = 70/169 (42%), Positives = 98/169 (58%), Gaps = 1/169 (0%)
Query 15 RRQAIVEAAERVIARQGLGGLSHRRVAAEANVPVGSTTYYFNDLDALREAALAHAANASA 74
RRQ I++AA RV+ ++G+ GLSHR VAAEA+VP+GSTTY+F LD L AAL A A
Sbjct 29 RRQRIIDAAIRVVGQKGIAGLSHRTVAAEADVPLGSTTYHFATLDDLMVAALRQANEGFA 88
Query 75 DLLAQWRSDLDKDRDLAATLARLTTVYL-ADQDRYRTLNELYMAAAHRPELQRLARLWPD 133
++A + D + DL+ LAR+ +L D+ ELY+AA RP L+ +A W +
Sbjct 89 RVVAAHPALSDPEADLSGELARVLGEWLGGDRTGVELEYELYLAALRRPALRPVAAEWAE 148
Query 134 GLLALLEPRIGRRAANAVTVFFDGATLHALITGTPLSTDELTDAIARLV 182
G+ ALL R A A+ DG L L+T TP + + + RL+
Sbjct 149 GVGALLAARTDPTTARALVAVLDGICLQVLLTDTPYDEEYAREVLTRLI 197
>gi|297198854|ref|ZP_06916251.1| ebrA repressor [Streptomyces sviceus ATCC 29083]
gi|197711225|gb|EDY55259.1| ebrA repressor [Streptomyces sviceus ATCC 29083]
Length=183
Score = 108 bits (271), Expect = 3e-22, Method: Compositional matrix adjust.
Identities = 74/179 (42%), Positives = 95/179 (54%), Gaps = 2/179 (1%)
Query 8 RPRDPAGRRQAIVEAAERVIARQGLGGLSHRRVAAEANVPVGSTTYYFNDLDALREAALA 67
R DP RRQ I++AA RV+ R+GL GLSHR AAEA+VP+GSTTY+F LD L AAL
Sbjct 4 RRHDPE-RRQRIIDAAIRVVGRKGLAGLSHRSAAAEADVPLGSTTYHFKSLDELMVAALC 62
Query 68 HAANASADLLAQWRSDLDKDRDLAATLARLTTVYL-ADQDRYRTLNELYMAAAHRPELQR 126
A+ A +A + D DL A LAR+ +L D+ ELY+AA RP L+
Sbjct 63 QASEGFAKAVAAHGALDDPGGDLPAGLARVLGDWLGGDRTGVELEYELYLAALRRPALRP 122
Query 127 LARLWPDGLLALLEPRIGRRAANAVTVFFDGATLHALITGTPLSTDELTDAIARLVADG 185
+A W D L L R A A+ DG L L+TG P + R++ G
Sbjct 123 VAAEWADDLAERLAHRTDPVTARALVALMDGICLQVLLTGAPYDEGYAREVFGRVIPAG 181
>gi|300789381|ref|YP_003769672.1| TetR family transcriptional regulator [Amycolatopsis mediterranei
U32]
gi|299798895|gb|ADJ49270.1| TetR family transcriptional regulator [Amycolatopsis mediterranei
U32]
gi|340531028|gb|AEK46233.1| TetR family transcriptional regulator [Amycolatopsis mediterranei
S699]
Length=192
Score = 107 bits (267), Expect = 1e-21, Method: Compositional matrix adjust.
Identities = 71/181 (40%), Positives = 96/181 (54%), Gaps = 3/181 (1%)
Query 7 RRPRDPAGRRQAIVEAAERVIARQGLGGLSHRRVAAEANVPVGSTTYYFNDLDALREAAL 66
R P DP RR I +AA V+A++G+ G++HR VAA A VP+GSTTY+F LD L E AL
Sbjct 12 RGPNDPE-RRARIAKAAIEVVAQRGIDGVTHRAVAAAAGVPLGSTTYHFATLDDLLEVAL 70
Query 67 AHAANASADLLAQWRSDLDKDRDLAATLARLTTVYLADQDRYRTLN-ELYMAAAHRPELQ 125
AA + L +W S L D D AA LA L Y+ +Q R + +LY+AA HRP L+
Sbjct 71 HEAAERNVHALKEWESALPPDTDFAAALADLVMGYINEQYRDTVVEYDLYVAALHRPALR 130
Query 126 RLARLWPDGLLALLEPRIGRRAANAVTVFFDGATLHALITGTPLSTDELTDAIARLVADG 185
+ + W D L+A R + F G + A + P E + + R DG
Sbjct 131 KASAAWDDALIAFFGSRTDPLTGRLLAGLFCGLLMQAAL-ADPRPNREEIETLFRRAIDG 189
Query 186 P 186
P
Sbjct 190 P 190
>gi|302533771|ref|ZP_07286113.1| ebrA repressor [Streptomyces sp. C]
gi|302442666|gb|EFL14482.1| ebrA repressor [Streptomyces sp. C]
Length=187
Score = 105 bits (261), Expect = 5e-21, Method: Compositional matrix adjust.
Identities = 75/179 (42%), Positives = 99/179 (56%), Gaps = 11/179 (6%)
Query 15 RRQAIVEAAERVIARQGLGGLSHRRVAAEANVPVGSTTYYFNDLDALREAALAHAANASA 74
RRQ I++AA RV++ +G+ GLSHR AAEA+VP+GSTTY+F LD L AAL A A A
Sbjct 12 RRQRIIDAAIRVVSAKGIAGLSHRSAAAEADVPLGSTTYHFETLDDLLVAALRQANEAYA 71
Query 75 DLLAQWRSDLDKDRDLAATLARLT-TVYLADQDRYRTLNELYMAAAHRPELQRLARLWPD 133
L + + DLA LARL V AD+ R ELY+AA RP L+ +A W +
Sbjct 72 PALV-----IREGEDLAGALARLLGEVLEADRGRAELEYELYLAALRRPALRPVAAEWCE 126
Query 134 GLLALLEPRIGRRAANAVTVFFDGATLHALITGTPLSTDELTDAIARLVAD-----GPE 187
+ A L A A+ DG +L L+TGTP + + + R+VA GPE
Sbjct 127 AVTAALAEHTDPLTARALVAVMDGISLQVLLTGTPYDGAYVRELLRRVVAGADGRRGPE 185
>gi|294628707|ref|ZP_06707267.1| transcriptional regulatory protein [Streptomyces sp. e14]
gi|292832040|gb|EFF90389.1| transcriptional regulatory protein [Streptomyces sp. e14]
Length=179
Score = 103 bits (258), Expect = 1e-20, Method: Compositional matrix adjust.
Identities = 70/165 (43%), Positives = 91/165 (56%), Gaps = 1/165 (0%)
Query 19 IVEAAERVIARQGLGGLSHRRVAAEANVPVGSTTYYFNDLDALREAALAHAANASADLLA 78
I++AA RV+ R G+ GLSHR VAAEA+VP+GSTTY+F LD L AAL + L+A
Sbjct 14 IIDAAIRVVRRAGIAGLSHRTVAAEADVPLGSTTYHFATLDELMVAALRQSGEGFCRLVA 73
Query 79 QWRSDLDKDRDLAATLARLTTVYLADQDRYRTLN-ELYMAAAHRPELQRLARLWPDGLLA 137
D DLA LA +LA L ELY+AA RP L+ +A W D L A
Sbjct 74 AREGLTDPGGDLAGELAAALGEWLAAGRAGAELEYELYLAALRRPALRPVAAGWADDLAA 133
Query 138 LLEPRIGRRAANAVTVFFDGATLHALITGTPLSTDELTDAIARLV 182
LL PR A A+ DG L+ L+TG + +A+AR++
Sbjct 134 LLAPRTDPLTARALVALMDGICLNVLLTGGSYDEEYAREALARMI 178
>gi|302550604|ref|ZP_07302946.1| TetR family transcriptional regulator [Streptomyces viridochromogenes
DSM 40736]
gi|302468222|gb|EFL31315.1| TetR family transcriptional regulator [Streptomyces viridochromogenes
DSM 40736]
Length=183
Score = 102 bits (255), Expect = 2e-20, Method: Compositional matrix adjust.
Identities = 73/181 (41%), Positives = 95/181 (53%), Gaps = 2/181 (1%)
Query 8 RPRDPAGRRQAIVEAAERVIARQGLGGLSHRRVAAEANVPVGSTTYYFNDLDALREAALA 67
R DP RRQ I++AA RV+ +G+ GLSHR AAEA+VP+GSTTY+F LD L AAL
Sbjct 4 RRHDPE-RRQRIIDAAIRVVGAKGIAGLSHRSAAAEADVPLGSTTYHFKTLDELLVAALR 62
Query 68 HAANASADLLAQWRSDLDKDRDLAATLARLTTVYLA-DQDRYRTLNELYMAAAHRPELQR 126
A A ++A D DLAA LA +LA D+ ELY+AA RP L+
Sbjct 63 QANEGFAKVIASRGGLEDPRTDLAAELAGSMGEWLAGDRTGVELEYELYLAALRRPALRP 122
Query 127 LARLWPDGLLALLEPRIGRRAANAVTVFFDGATLHALITGTPLSTDELTDAIARLVADGP 186
+A W + + L R A A+ DG L L+TG P + + R+VA
Sbjct 123 VADEWAEQVAESLSRRTDPVTARALVAVVDGICLQVLLTGVPYDESYAREVLGRIVAGAR 182
Query 187 E 187
E
Sbjct 183 E 183
>gi|290961362|ref|YP_003492544.1| repressor [Streptomyces scabiei 87.22]
gi|260650888|emb|CBG74005.1| putative repressor [Streptomyces scabiei 87.22]
Length=178
Score = 100 bits (250), Expect = 9e-20, Method: Compositional matrix adjust.
Identities = 71/176 (41%), Positives = 93/176 (53%), Gaps = 2/176 (1%)
Query 8 RPRDPAGRRQAIVEAAERVIARQGLGGLSHRRVAAEANVPVGSTTYYFNDLDALREAALA 67
R DP RRQ I++AA RV+A +G+ GLSHR AAEA+VP+GSTTY+F LD L AAL
Sbjct 3 RRYDPE-RRQRIIDAAIRVVAERGIAGLSHRSAAAEADVPLGSTTYHFKTLDDLMVAALR 61
Query 68 HAANASADLLAQWRSDLDKDRDLAATLARLTTVYL-ADQDRYRTLNELYMAAAHRPELQR 126
A A +A + D DLAA LA L + D+ ELY+AA RP L+
Sbjct 62 QANERFAKSVAAREALRDPGTDLAAELAALGGEWFTGDRTGLEVEYELYLAALRRPALRP 121
Query 127 LARLWPDGLLALLEPRIGRRAANAVTVFFDGATLHALITGTPLSTDELTDAIARLV 182
+A W L R A A+ DG L L+TG P + + +AR++
Sbjct 122 VADEWGRAFADCLADRTDPVTARALVALVDGICLQVLLTGAPYDEEYAREVLARVI 177
>gi|29832878|ref|NP_827512.1| TetR family transcriptional regulator [Streptomyces avermitilis
MA-4680]
gi|29609999|dbj|BAC74047.1| putative TetR-family transcriptional regulator [Streptomyces
avermitilis MA-4680]
Length=178
Score = 99.4 bits (246), Expect = 3e-19, Method: Compositional matrix adjust.
Identities = 71/170 (42%), Positives = 94/170 (56%), Gaps = 3/170 (1%)
Query 15 RRQAIVEAAERVIARQGLGGLSHRRVAAEANVPVGSTTYYFNDLDALREAALAHAANASA 74
RRQ I++AA RV+ +G+ GLSHR VAAEA+VP+GSTTY+F LD L AAL A A
Sbjct 9 RRQRIIDAAIRVVGDKGIAGLSHRSVAAEADVPLGSTTYHFKTLDDLMVAALRQANEGFA 68
Query 75 DLLAQWRSDLDKDR-DLAATLARLTTVYLA-DQDRYRTLNELYMAAAHRPELQRLARLWP 132
++A R L+ R DLA +A L +LA D+ ELY+AA RP L+ +A
Sbjct 69 KVVAA-RGHLEDPRADLAGDIAALIGDWLAGDRTGVELEYELYLAALRRPALRPVAAECI 127
Query 133 DGLLALLEPRIGRRAANAVTVFFDGATLHALITGTPLSTDELTDAIARLV 182
DG + R A A+ DG L L+TG P + +ARL+
Sbjct 128 DGFAEAVARRTDPVTARALVALVDGICLQVLLTGAPYDEAYARELLARLI 177
>gi|320011459|gb|ADW06309.1| transcriptional regulator, TetR family [Streptomyces flavogriseus
ATCC 33331]
Length=205
Score = 98.2 bits (243), Expect = 6e-19, Method: Compositional matrix adjust.
Identities = 71/180 (40%), Positives = 92/180 (52%), Gaps = 2/180 (1%)
Query 8 RPRDPAGRRQAIVEAAERVIARQGLGGLSHRRVAAEANVPVGSTTYYFNDLDALREAALA 67
R DP RR+ I+EAA RV+ QG+ GLSHR VAAEA+VP+GSTTY+F LD L AAL
Sbjct 3 RRHDPE-RRERIIEAAIRVVGAQGIAGLSHRSVAAEADVPLGSTTYHFASLDELLVAALR 61
Query 68 HAANASADLLAQWRSDLDKDRDLAATLARLTTVYLADQDRYRTLN-ELYMAAAHRPELQR 126
A ++ + D LA L RL + + L ELY+AA RP L+
Sbjct 62 RCNENFARMVREGDGLADPAVPLADALTRLLGEWFSGGRGPMELEYELYLAALRRPVLRP 121
Query 127 LARLWPDGLLALLEPRIGRRAANAVTVFFDGATLHALITGTPLSTDELTDAIARLVADGP 186
+A W D L+ + R A A+T DG L L+TG + +ARL P
Sbjct 122 VAGEWADALVEPIAHRTDPATARALTALLDGICLQVLLTGGEFDPVYTREMLARLAEGEP 181
>gi|302546314|ref|ZP_07298656.1| TetR family transcriptional regulator [Streptomyces hygroscopicus
ATCC 53653]
gi|302463932|gb|EFL27025.1| TetR family transcriptional regulator [Streptomyces himastatinicus
ATCC 53653]
Length=180
Score = 97.4 bits (241), Expect = 1e-18, Method: Compositional matrix adjust.
Identities = 72/176 (41%), Positives = 94/176 (54%), Gaps = 3/176 (1%)
Query 8 RPRDPAGRRQAIVEAAERVIARQGLGGLSHRRVAAEANVPVGSTTYYFNDLDALREAALA 67
R DP RRQ I++AA V+ +G+GGLSHR VAAEA+VP+GSTTY+F LD L AAL
Sbjct 4 RRYDPE-RRQRIIDAAIAVVGERGIGGLSHRAVAAEADVPLGSTTYHFATLDDLLVAALD 62
Query 68 HAANASADLLAQWRSDLDKDRDLAATLARLTTVYL-ADQDRYRTLNELYMAAAHRPELQR 126
+ +W D D LA +A L + L D+ R ELY+AA R ++
Sbjct 63 QVNAEWLADMERWERDAPPDAPLADGMAGLMEMLLTGDRKRLELEYELYLAALRRTSVRP 122
Query 127 LARLWPDGLLALLEPRIGR-RAANAVTVFFDGATLHALITGTPLSTDELTDAIARL 181
LA + D + LL R G A A+ FDG L L+TG +E A AR+
Sbjct 123 LAAAFLDRMTELLVRRTGDVDVARAINALFDGMLLQVLLTGREFDREEARAAFARV 178
>gi|294632913|ref|ZP_06711472.1| conserved hypothetical protein [Streptomyces sp. e14]
gi|292830694|gb|EFF89044.1| conserved hypothetical protein [Streptomyces sp. e14]
Length=192
Score = 96.7 bits (239), Expect = 2e-18, Method: Compositional matrix adjust.
Identities = 72/165 (44%), Positives = 89/165 (54%), Gaps = 0/165 (0%)
Query 19 IVEAAERVIARQGLGGLSHRRVAAEANVPVGSTTYYFNDLDALREAALAHAANASADLLA 78
IVEAA ++ GLGGL+HR VA A V +GSTT+YF LD LREAAL H A+ LA
Sbjct 16 IVEAAAALVIEVGLGGLTHRMVANRAQVALGSTTHYFATLDDLREAALRHLADQVDSGLA 75
Query 79 QWRSDLDKDRDLAATLARLTTVYLADQDRYRTLNELYMAAAHRPELQRLARLWPDGLLAL 138
+ + LD+ A LA YLAD R L AA P + LA D L+AL
Sbjct 76 EVKRSLDEHGADPAVLAEALFAYLADTHLVRADTCLLSAAVVDPHFRSLALQTFDRLVAL 135
Query 139 LEPRIGRRAANAVTVFFDGATLHALITGTPLSTDELTDAIARLVA 183
+ +G R A A+ VF GA HA + PL LT+ I RL+A
Sbjct 136 MSAYVGVREATAIAVFAQGAAAHAALHEEPLDVASLTEVITRLLA 180
>gi|326780054|ref|ZP_08239319.1| transcriptional regulator, TetR family [Streptomyces cf. griseus
XylebKG-1]
gi|326660387|gb|EGE45233.1| transcriptional regulator, TetR family [Streptomyces griseus
XylebKG-1]
Length=198
Score = 95.9 bits (237), Expect = 3e-18, Method: Compositional matrix adjust.
Identities = 74/193 (39%), Positives = 93/193 (49%), Gaps = 19/193 (9%)
Query 11 DPAGRRQAIVEAAERVIARQGLGGLSHRRVAAEANVPVGSTTYYFNDLDALREA------ 64
DP GRR+ IV+AA RVIA G+ GLSHR VAAEA+VP+GSTTY+F LD L A
Sbjct 6 DP-GRRERIVDAALRVIAADGIAGLSHRTVAAEADVPLGSTTYHFGSLDELLVAALRRYN 64
Query 65 -----------ALAHAANASADLLAQWRSDLDKDRDLAATLARLTTVYLADQDRYRTLN- 112
ALA AS + D LA L RL + A + L
Sbjct 65 DNFVRELRGSQALAGPTGASGPTGPTGPAGPDGPAGLAEELTRLLGRWFAGERGAIELEY 124
Query 113 ELYMAAAHRPELQRLARLWPDGLLALLEPRIGRRAANAVTVFFDGATLHALITGTPLSTD 172
ELY+AA RP L+ +A W + + LL R R A A+ DG L L+TG
Sbjct 125 ELYLAALRRPVLRPVAAEWTEEAIELLSRRTDRETARALVALMDGVCLQVLLTGGAFDAP 184
Query 173 ELTDAIARLVADG 185
+ + R+V G
Sbjct 185 RTREMLGRIVDGG 197
>gi|344998942|ref|YP_004801796.1| TetR family transcriptional regulator [Streptomyces sp. SirexAA-E]
gi|344314568|gb|AEN09256.1| transcriptional regulator, TetR family [Streptomyces sp. SirexAA-E]
Length=183
Score = 94.0 bits (232), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 70/179 (40%), Positives = 92/179 (52%), Gaps = 2/179 (1%)
Query 8 RPRDPAGRRQAIVEAAERVIARQGLGGLSHRRVAAEANVPVGSTTYYFNDLDALREAALA 67
R DP RR I+EAA R++A +G+ GLSHR VAAEA+VP+GSTTY+F LD L AAL
Sbjct 3 RRYDPE-RRDRIIEAAIRIVADRGIAGLSHRTVAAEADVPLGSTTYHFASLDELLVAALR 61
Query 68 HAANASADLLAQWRSDLDKDRDLAATLARLTTVYLADQDRYRTLN-ELYMAAAHRPELQR 126
+ + D + DLA L RL + A + L ELY+AA RP L+
Sbjct 62 RCNENFVRTVRESARLADPEADLADELTRLLGEWFAGERGAIELEYELYLAALRRPALRP 121
Query 127 LARLWPDGLLALLEPRIGRRAANAVTVFFDGATLHALITGTPLSTDELTDAIARLVADG 185
+A W D LL R A A+ DG +L L+ G + +AR+V G
Sbjct 122 VAAEWADEAGELLARRTDPATARALVALLDGISLQVLLAGGDFDAAYTREMLARIVEGG 180
>gi|328881595|emb|CCA54834.1| Transcriptional regulator, TetR family [Streptomyces venezuelae
ATCC 10712]
Length=182
Score = 93.6 bits (231), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 75/164 (46%), Positives = 95/164 (58%), Gaps = 4/164 (2%)
Query 8 RPR--DPAGRRQAIVEAAERVIARQGLGGLSHRRVAAEANVPVGSTTYYFNDLDALREAA 65
RPR DPA RR+ IV+AA RV AR G+ GLSHR VAAEA+VP+GSTTY+F LD L AA
Sbjct 3 RPRRHDPA-RRERIVDAALRVAARSGIAGLSHRTVAAEADVPLGSTTYHFASLDELLVAA 61
Query 66 LAHAANASADLLAQWRSDLDKDRDLAATLARLTTVYL-ADQDRYRTLNELYMAAAHRPEL 124
L A LL + + DLAA LARL +L ++ R ELY+AA RP L
Sbjct 62 LRKANEGFDRLLRENSALTAPGTDLAAALARLLGEWLGGERARVELEYELYLAALRRPAL 121
Query 125 QRLARLWPDGLLALLEPRIGRRAANAVTVFFDGATLHALITGTP 168
+ +A W + ++A L P A A+ DG L +L+T P
Sbjct 122 RPVAVEWAETVVAALSPHTDPVTARALVALMDGICLQSLLTDEP 165
>gi|262201944|ref|YP_003273152.1| TetR family transcriptional regulator [Gordonia bronchialis DSM
43247]
gi|262085291|gb|ACY21259.1| regulatory protein TetR [Gordonia bronchialis DSM 43247]
Length=196
Score = 91.3 bits (225), Expect = 7e-17, Method: Compositional matrix adjust.
Identities = 63/167 (38%), Positives = 83/167 (50%), Gaps = 0/167 (0%)
Query 19 IVEAAERVIARQGLGGLSHRRVAAEANVPVGSTTYYFNDLDALREAALAHAANASADLLA 78
I++AA +I G GL+HR VA A VP+GSTT YF LD LREA L H A+ +
Sbjct 22 IIDAAAELIVELGSAGLTHRLVADRAGVPLGSTTQYFTSLDELREAGLHHLADEIDGEVR 81
Query 79 QWRSDLDKDRDLAATLARLTTVYLADQDRYRTLNELYMAAAHRPELQRLARLWPDGLLAL 138
+ L + A + YL D R L AA P L LA P ++ L
Sbjct 82 DFAGVLRERGASADVFGEMLHAYLCDIRLVRADLALLNAAFVDPALGPLALRLPTAVIYL 141
Query 139 LEPRIGRRAANAVTVFFDGATLHALITGTPLSTDELTDAIARLVADG 185
L P IG + A AV + DG +H ++ GT + EL+DA+A L G
Sbjct 142 LIPHIGEQRARAVAAYVDGVAMHTVLRGTTPTIAELSDALAALTNSG 188
>gi|182439398|ref|YP_001827117.1| TetR family transcriptional regulator [Streptomyces griseus subsp.
griseus NBRC 13350]
gi|178467914|dbj|BAG22434.1| putative TetR-family transcriptional regulator [Streptomyces
griseus subsp. griseus NBRC 13350]
Length=198
Score = 90.9 bits (224), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 72/193 (38%), Positives = 90/193 (47%), Gaps = 19/193 (9%)
Query 11 DPAGRRQAIVEAAERVIARQGLGGLSHRRVAAEANVPVGSTTYYFNDLDALREAAL---- 66
DP GRR+ IV+AA RVIA G+ GLSHR VAAEA+VP+GSTTY+F LD L AAL
Sbjct 6 DP-GRRERIVDAALRVIAADGIAGLSHRTVAAEADVPLGSTTYHFGSLDELLVAALRRYN 64
Query 67 -------------AHAANASADLLAQWRSDLDKDRDLAATLARLTTVYLADQDRYRTLN- 112
A S LA L RL + A + L
Sbjct 65 DNFVRELRGSQALAGPGGVSGPTGPAGPDGPAGPAGLAEELTRLLGRWFAGERGAIELEY 124
Query 113 ELYMAAAHRPELQRLARLWPDGLLALLEPRIGRRAANAVTVFFDGATLHALITGTPLSTD 172
ELY+AA RP L+ +A W + + LL R R A A+ DG L L+TG
Sbjct 125 ELYLAALRRPVLRPVAAEWTEEAVELLSRRTDRETARALVALMDGVCLQVLLTGGAFDAP 184
Query 173 ELTDAIARLVADG 185
+ + R+V G
Sbjct 185 RTREMLGRIVDGG 197
>gi|254384161|ref|ZP_04999505.1| ebrA repressor [Streptomyces sp. Mg1]
gi|194343050|gb|EDX24016.1| ebrA repressor [Streptomyces sp. Mg1]
Length=199
Score = 88.2 bits (217), Expect = 6e-16, Method: Compositional matrix adjust.
Identities = 65/169 (39%), Positives = 89/169 (53%), Gaps = 4/169 (2%)
Query 15 RRQAIVEAAERVIARQGLGGLSHRRVAAEANVPVGSTTYYFNDLDALREAALAHAANASA 74
RRQ I++AA RV+ +G+ GLSHR VAAEA+VP+GSTTY+F LD L AAL A A
Sbjct 31 RRQRIIDAAIRVVGAKGIAGLSHRSVAAEADVPLGSTTYHFKTLDELLVAALRQANQAFT 90
Query 75 DLLAQWRSDLDKDRDLAAT-LARLTTVYLADQDRYRTLNELYMAAAHRPELQRLARLWPD 133
L + D+A + L + AD+ R ELY+AA RP L+ +A W +
Sbjct 91 VTLPATPAPAG---DVAGSLARLLGRLLAADRGRVELEYELYLAALRRPALRPVAAEWYE 147
Query 134 GLLALLEPRIGRRAANAVTVFFDGATLHALITGTPLSTDELTDAIARLV 182
+ L P A A+ DG L L+T TP + +AR++
Sbjct 148 AVATALAPWTDPVTARALVAVMDGICLQVLLTDTPYDERYAREVLARVL 196
>gi|257057139|ref|YP_003134971.1| hypothetical protein Svir_31710 [Saccharomonospora viridis DSM
43017]
gi|256587011|gb|ACU98144.1| uncharacterized conserved protein [Saccharomonospora viridis
DSM 43017]
Length=189
Score = 88.2 bits (217), Expect = 6e-16, Method: Compositional matrix adjust.
Identities = 63/164 (39%), Positives = 81/164 (50%), Gaps = 4/164 (2%)
Query 7 RRPRDPAGRRQAIVEAAERVIARQGLGGLSHRRVAAEANVPVGSTTYYFNDLDALREAAL 66
R P DP RR I AA VIA +G+ L+HR VAAEA VP+GSTTY+F LD L AL
Sbjct 13 RGPNDP-DRRNRIARAAITVIAERGINALTHRMVAAEAGVPLGSTTYHFATLDDLVAVAL 71
Query 67 AHAANASADLLAQWRSDLDKDRDLAATLARLTTVYLADQDRYRTLNE--LYMAAAHRPEL 124
AA + D L +W + L +D DL L L + Q R T+ E LY A RP L
Sbjct 72 DEAARRNIDALREWNAALPEDVDLVTALTDLVLDSVTKQ-RADTIAEYNLYALALQRPHL 130
Query 125 QRLARLWPDGLLALLEPRIGRRAANAVTVFFDGATLHALITGTP 168
+R A W + L + R + G + ++ TP
Sbjct 131 RRAAVAWDNALADVFSTRTDPLTGRMIATLTCGLMMQTVLGETP 174
>gi|269219739|ref|ZP_06163593.1| putative transcriptional regulatory protein [Actinomyces sp.
oral taxon 848 str. F0332]
gi|269210981|gb|EEZ77321.1| putative transcriptional regulatory protein [Actinomyces sp.
oral taxon 848 str. F0332]
Length=248
Score = 87.8 bits (216), Expect = 8e-16, Method: Compositional matrix adjust.
Identities = 65/182 (36%), Positives = 93/182 (52%), Gaps = 7/182 (3%)
Query 8 RPRDPAGRRQAIVEAAERVIARQGLGGLSHRRVAAEANVPVGSTTYYFNDLDALREA--- 64
R RDP RR+AI+ AA VI +G L+HR VAA A V +GSTT YF+ ++ LRE
Sbjct 58 RKRDPEARRRAILNAAIDVIVEKGAAALTHRAVAARAGVSLGSTTKYFSSIEDLRENAMD 117
Query 65 ALAHAANASADLLAQWRSDLDKDRDLAATLARLTTVYLADQDRYRTLNELYMAAAHRPEL 124
AL +A D + S+L+ D+ + L YL D + R L A A L
Sbjct 118 ALVREMDAGVD---AFESELEACDDVESYCIGLAYEYLRDVRQVRADVALLNAGARDDGL 174
Query 125 QRLARLWPDGLLALLEPRIGRRAANAVTVFFDGATLHALITGTPLSTDELTDAIARLVAD 184
+ +A PD L+A L P G A A+ + +GA +H+ + TP+ E+ + I R +
Sbjct 175 REIALRNPDRLIAALAPHFGAERAMALELCLEGAVVHSALRSTPIDK-EVIERIFRGIIS 233
Query 185 GP 186
P
Sbjct 234 AP 235
>gi|296137890|ref|YP_003645133.1| TetR family transcriptional regulator [Tsukamurella paurometabola
DSM 20162]
gi|296026024|gb|ADG76794.1| transcriptional regulator, TetR family [Tsukamurella paurometabola
DSM 20162]
Length=192
Score = 87.4 bits (215), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 64/155 (42%), Positives = 85/155 (55%), Gaps = 8/155 (5%)
Query 19 IVEAAERVIARQGLGGLSHRRVAAEANVPVGSTTYYFNDLDALREAALAHAANASADLLA 78
IV+AA ++ G L+HR+VAA A VP+GSTT YF LD LREAAL + D
Sbjct 17 IVDAAAALVLESGADALTHRKVAARAGVPLGSTTQYFATLDDLREAALRNL----MDEAE 72
Query 79 QWRSDLDKD--RDLAATLARLTTV--YLADQDRYRTLNELYMAAAHRPELQRLARLWPDG 134
QW +DL+ + RD A++ A + YL+D R + AAA P+++ LAR W
Sbjct 73 QWLADLEAEFVRDGASSAAYTGALHRYLSDPQLVRGDFAMTCAAASSPDMEELARHWTAR 132
Query 135 LLALLEPRIGRRAANAVTVFFDGATLHALITGTPL 169
L+ L I A AV F DGAT+ A+I PL
Sbjct 133 LVEALARYIPVENARAVATFSDGATMDAVIAERPL 167
>gi|326383954|ref|ZP_08205638.1| regulatory protein TetR [Gordonia neofelifaecis NRRL B-59395]
gi|326197413|gb|EGD54603.1| regulatory protein TetR [Gordonia neofelifaecis NRRL B-59395]
Length=183
Score = 86.7 bits (213), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 65/174 (38%), Positives = 83/174 (48%), Gaps = 0/174 (0%)
Query 10 RDPAGRRQAIVEAAERVIARQGLGGLSHRRVAAEANVPVGSTTYYFNDLDALREAALAHA 69
RDP RR AIVEAA ++ G L+HRRVA A VP+GSTT YF+ +D LR ALA
Sbjct 4 RDPEARRAAIVEAAADLVVELGPERLTHRRVAERAGVPLGSTTQYFSSIDDLRTQALARL 63
Query 70 ANASADLLAQWRSDLDKDRDLAATLARLTTVYLADQDRYRTLNELYMAAAHRPELQRLAR 129
A D L R L L YL + L AAA EL+ LA
Sbjct 64 ATEIDDDLDAVRQSLADSGGSVEVLVEQMHDYLTNSRNVSADVSLMSAAAFDAELRTLAL 123
Query 130 LWPDGLLALLEPRIGRRAANAVTVFFDGATLHALITGTPLSTDELTDAIARLVA 183
W L+ +L +G A A+ + DG T+HA + P+S L +A +A
Sbjct 124 RWQHNLVDILTGYVGPDNALALAMLADGVTVHAALHDAPVSKQFLHTLVAPFMA 177
>gi|333920137|ref|YP_004493718.1| hypothetical protein AS9A_2471 [Amycolicicoccus subflavus DQS3-9A1]
gi|333482358|gb|AEF40918.1| hypothetical protein AS9A_2471 [Amycolicicoccus subflavus DQS3-9A1]
Length=193
Score = 85.9 bits (211), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 66/161 (41%), Positives = 84/161 (53%), Gaps = 4/161 (2%)
Query 7 RRPRDPAGRRQAIVEAAERVIARQGLGGLSHRRVAAEANVPVGSTTYYFNDLDALREAAL 66
R P DP RR IVEAA V+ QG+ L+HRRVAA A VP+GSTTY+F LD L AAL
Sbjct 10 RGPTDP-DRRDRIVEAAIVVLTEQGVSALTHRRVAAAAEVPLGSTTYHFATLDDLLAAAL 68
Query 67 AHAANASADLLAQWRSDLDKDRDLAATLARLTTVYLADQDRYRTLNE--LYMAAAHRPEL 124
AA S L W LD D D+A L+ V + R T+ E LY A HRP L
Sbjct 69 TKAAERSVAALRAWEESLDPDADIAHALSEF-VVRSVSETRSDTMAEYNLYALALHRPHL 127
Query 125 QRLARLWPDGLLALLEPRIGRRAANAVTVFFDGATLHALIT 165
+ A W + L +L R A + + V G + +++
Sbjct 128 RAAAVAWDNALAEVLSRRTDPVAGHMLGVLLCGLLMQVVLS 168
>gi|295839578|ref|ZP_06826511.1| TetR family transcriptional regulator [Streptomyces sp. SPB74]
gi|295827546|gb|EDY43772.2| TetR family transcriptional regulator [Streptomyces sp. SPB74]
Length=189
Score = 84.3 bits (207), Expect = 8e-15, Method: Compositional matrix adjust.
Identities = 71/177 (41%), Positives = 90/177 (51%), Gaps = 2/177 (1%)
Query 15 RRQAIVEAAERVIARQGLGGLSHRRVAAEANVPVGSTTYYFNDLDALREAALAHAANASA 74
RRQ I++AA RV R G+ GLSHR AAEA+VP+GSTTY+F LD L AAL A A
Sbjct 11 RRQRIIDAAIRVTGRSGIAGLSHRTAAAEADVPLGSTTYHFATLDDLLVAALRQANENFA 70
Query 75 DLLAQWRSDLDKDRDLAATLARLTTVYL-ADQDRYRTLNELYMAAAHRPELQRLARLWPD 133
L+ + LAA LA +L AD+ ELY+AA RP L+ +A W
Sbjct 71 RLVRDRGALRAPPGGLAAALADAMGAWLAADRANAELEYELYLAALRRPPLRPVAAEWSR 130
Query 134 GLLALLEPRIGRRAANAVTVFFDGATLHALITGTPLSTDELTDAIARLV-ADGPEQR 189
L L R A AV DG L L+T +P + + R++ DGP R
Sbjct 131 ALEEPLTARTDPATARAVVALMDGLCLQVLLTDSPYDEAYAREMLGRVLREDGPPAR 187
>gi|318056391|ref|ZP_07975114.1| hypothetical protein SSA3_00505 [Streptomyces sp. SA3_actG]
gi|318075708|ref|ZP_07983040.1| hypothetical protein SSA3_03097 [Streptomyces sp. SA3_actF]
Length=181
Score = 83.2 bits (204), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 69/176 (40%), Positives = 90/176 (52%), Gaps = 2/176 (1%)
Query 8 RPRDPAGRRQAIVEAAERVIARQGLGGLSHRRVAAEANVPVGSTTYYFNDLDALREAALA 67
R DP RRQ I++AA RV+ R G+ GLSHR AAEA+VP+GSTTY+F LD L AAL
Sbjct 5 RRYDP-DRRQRIIDAAIRVVGRSGIAGLSHRSAAAEADVPLGSTTYHFATLDDLLVAALR 63
Query 68 HAANASADLLAQWRSDLDKDRDLAATLARLTTVYLADQDRYRTLN-ELYMAAAHRPELQR 126
A A L+ LAA LA +LA + L ELY+AA +P L+
Sbjct 64 QANENFARLVRDLGVLRAPPAGLAAALAGAMGAWLAADRAHAELEYELYLAAVRKPVLRP 123
Query 127 LARLWPDGLLALLEPRIGRRAANAVTVFFDGATLHALITGTPLSTDELTDAIARLV 182
+A W L L R A AV DG L L+T +P + + + R++
Sbjct 124 VAAEWSRALEEPLAARTDPATARAVVALMDGLCLQVLLTDSPYDEEYAREMLGRVL 179
>gi|311280270|ref|YP_003942501.1| transcriptional regulator, TetR family [Enterobacter cloacae
SCF1]
gi|308749465|gb|ADO49217.1| transcriptional regulator, TetR family [Enterobacter cloacae
SCF1]
Length=188
Score = 83.2 bits (204), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 52/183 (29%), Positives = 88/183 (49%), Gaps = 2/183 (1%)
Query 7 RRPRDPAGRRQAIVEAAERVIARQGLGGLSHRRVAAEANVPVGSTTYYFNDLDALREAAL 66
RRP DP RR+ I++A IAR G+ ++HR++A A+VP+GS TYYF+ +DAL E A
Sbjct 3 RRPNDPL-RRERIIQATLDTIARHGIQAVTHRKIAQCADVPLGSMTYYFSGIDALLEEAF 61
Query 67 AHAANASADLLAQWRSDLDKDRDLAATLARLTT-VYLADQDRYRTLNELYMAAAHRPELQ 125
+ + +D+ D + RL + + + ++Y + +P L+
Sbjct 62 TSFTAQMSRQYQAFFTDVLTPDDACDAITRLISGAEVTTARNMELMYQMYAFTSCKPALK 121
Query 126 RLARLWPDGLLALLEPRIGRRAANAVTVFFDGATLHALITGTPLSTDELTDAIARLVADG 185
+ + W LE A A+ F +G TLH + PL DE+ + R+ +
Sbjct 122 GVMQDWMQRSQQTLERWFDAPTARALDAFIEGMTLHFVTDRAPLGRDEIRQMVGRIAGEQ 181
Query 186 PEQ 188
++
Sbjct 182 KQK 184
>gi|302518364|ref|ZP_07270706.1| ebrA repressor [Streptomyces sp. SPB78]
gi|302427259|gb|EFK99074.1| ebrA repressor [Streptomyces sp. SPB78]
Length=181
Score = 82.8 bits (203), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 69/176 (40%), Positives = 90/176 (52%), Gaps = 2/176 (1%)
Query 8 RPRDPAGRRQAIVEAAERVIARQGLGGLSHRRVAAEANVPVGSTTYYFNDLDALREAALA 67
R DP RRQ I++AA RV+ R G+ GLSHR AAEA+VP+GSTTY+F LD L AAL
Sbjct 5 RRYDP-DRRQRIIDAAIRVVGRAGIAGLSHRSAAAEADVPLGSTTYHFATLDDLLVAALR 63
Query 68 HAANASADLLAQWRSDLDKDRDLAATLARLTTVYLADQDRYRTLN-ELYMAAAHRPELQR 126
A A L+ LAA LA +LA + L ELY+AA +P L+
Sbjct 64 QANENFARLVRDLGVLRAPPAGLAAALAGAMGAWLAADRAHAELEYELYLAAVRKPVLRP 123
Query 127 LARLWPDGLLALLEPRIGRRAANAVTVFFDGATLHALITGTPLSTDELTDAIARLV 182
+A W L L R A AV DG L L+T +P + + + R++
Sbjct 124 VAAEWSRALEEPLAARTDPATARAVVALMDGLCLQVLLTDSPYDEEYAREMLGRVL 179
>gi|333027966|ref|ZP_08456030.1| hypothetical protein STTU_5470 [Streptomyces sp. Tu6071]
gi|332747818|gb|EGJ78259.1| hypothetical protein STTU_5470 [Streptomyces sp. Tu6071]
Length=181
Score = 82.0 bits (201), Expect = 4e-14, Method: Compositional matrix adjust.
Identities = 68/176 (39%), Positives = 89/176 (51%), Gaps = 2/176 (1%)
Query 8 RPRDPAGRRQAIVEAAERVIARQGLGGLSHRRVAAEANVPVGSTTYYFNDLDALREAALA 67
R DP RRQ I++AA RV+ R G+ GLSHR AAEA+VP+GSTTY+F LD L AAL
Sbjct 5 RRYDP-DRRQRIIDAAIRVVGRSGIAGLSHRSAAAEADVPLGSTTYHFATLDDLLVAALR 63
Query 68 HAANASADLLAQWRSDLDKDRDLAATLARLTTVYLADQDRYRTLN-ELYMAAAHRPELQR 126
A L+ LAA LA +LA + L ELY+AA +P L+
Sbjct 64 QVNENFARLVRDLGVLRAPPAGLAAALAGAMGAWLAADRAHAELEYELYLAAVRKPVLRP 123
Query 127 LARLWPDGLLALLEPRIGRRAANAVTVFFDGATLHALITGTPLSTDELTDAIARLV 182
+A W L L R A AV DG L L+T +P + + + R++
Sbjct 124 VAAEWSRALEEPLAARTDPATARAVVALMDGLCLQVLLTDSPYDEEYAREMLGRVL 179
>gi|260597241|ref|YP_003209812.1| HTH-type transcriptional regulator YbjK [Cronobacter turicensis
z3032]
gi|260216418|emb|CBA29506.1| Uncharacterized HTH-type transcriptional regulator ybjK [Cronobacter
turicensis z3032]
Length=181
Score = 82.0 bits (201), Expect = 5e-14, Method: Compositional matrix adjust.
Identities = 58/184 (32%), Positives = 93/184 (51%), Gaps = 12/184 (6%)
Query 8 RPRDPAGRRQAIVEAAERVIARQGLGGLSHRRVAAEANVPVGSTTYYFNDLDALREAALA 67
R DP RR+ I+EA IA G ++HR++A EA VP+GS TYYF L+AL A
Sbjct 4 RQNDPQ-RRERILEATLACIAAHGFHHITHRKIALEAGVPLGSVTYYFTTLEALLAEAFT 62
Query 68 HAANASAD----LLAQWRSDLDKDRDLAATL--ARLTTVYLADQDRYRTLNELYMAAAHR 121
A + + L+AQ +S + L A + A++TT + + +LY A+ +
Sbjct 63 RFAESMSCQYQALMAQAQSREEACEALTALICGAQVTT-----PENMELMYQLYAYASRQ 117
Query 122 PELQRLARLWPDGLLALLEPRIGRRAANAVTVFFDGATLHALITGTPLSTDELTDAIARL 181
P+L+ + + W LE A A+ F +G TLH ++ PL+ + + + R+
Sbjct 118 PQLKIIMQDWMRRSQQTLETWFDPATARALDAFVEGMTLHYVVDREPLNRETIRSMVGRI 177
Query 182 VADG 185
V +G
Sbjct 178 VGEG 181
>gi|157146502|ref|YP_001453820.1| hypothetical protein CKO_02263 [Citrobacter koseri ATCC BAA-895]
gi|157083707|gb|ABV13385.1| hypothetical protein CKO_02263 [Citrobacter koseri ATCC BAA-895]
Length=185
Score = 81.6 bits (200), Expect = 6e-14, Method: Compositional matrix adjust.
Identities = 51/176 (29%), Positives = 85/176 (49%), Gaps = 2/176 (1%)
Query 7 RRPRDPAGRRQAIVEAAERVIARQGLGGLSHRRVAAEANVPVGSTTYYFNDLDALREAAL 66
RR DP RR IV+A + I G+ G++HR++AA A VP+GS TYYF+ +D L AL
Sbjct 7 RRANDPL-RRDKIVQATQEAIITHGIHGVTHRKIAAIAQVPLGSMTYYFSGIDELLIEAL 65
Query 67 AHAANASADLLAQWRSDLDKDRDLAATLARLTTVYLADQ-DRYRTLNELYMAAAHRPELQ 125
+ + + +D+ +D + + L D + +LY A+ +P L+
Sbjct 66 SRFTETMSHQFQLFFADVTNVQDACHAITDMIYSSLVTTPDNMELMYQLYAFASRKPALK 125
Query 126 RLARLWPDGLLALLEPRIGRRAANAVTVFFDGATLHALITGTPLSTDELTDAIARL 181
+ + W LE A A+ F +G TLH + PL+ +++ + R+
Sbjct 126 TVMQNWMQRSQQTLEQWFEPVTARALDAFIEGMTLHFVTDRAPLTREDILVMVKRI 181
>gi|271969071|ref|YP_003343267.1| TetR family transcriptional regulator [Streptosporangium roseum
DSM 43021]
gi|270512246|gb|ACZ90524.1| transcriptional regulator, TetR family [Streptosporangium roseum
DSM 43021]
Length=240
Score = 80.9 bits (198), Expect = 9e-14, Method: Compositional matrix adjust.
Identities = 65/186 (35%), Positives = 89/186 (48%), Gaps = 12/186 (6%)
Query 7 RRPR--DPAGRRQAIVEAAERVIARQGLGGLSHRRVAAEANVPVGSTTYYFNDLDALREA 64
RRPR DP RR I++ VIA GL G HR VA A+VP+GS TY+F LD L E
Sbjct 59 RRPRRHDP-NRRDRIIDVTIDVIAEHGLAGTGHRSVAEAADVPLGSMTYHFASLDELVEL 117
Query 65 ALAHAANASADLLAQWRSDLDKDRDLAATLARLTTVYLADQDRYR----TLNELYMAAAH 120
A + + AD + + DLAA +T V + D R R ELY+ AA
Sbjct 118 AFSRYVSVLADRFDARLAAAPESGDLAAI---VTDVIMVDFLRARRDLVLAYELYLGAAR 174
Query 121 RPELQRLARLWPDGLLALLEPRIGRRAANAVTVFFDGATLHALITGTPLSTDELTDAIAR 180
P L+ + R W LE A + +G LH + P++ +E+ A+AR
Sbjct 175 NPALREVTRTWMRRSRRALERLTDPATARVLDALLEGLVLHNFLATDPMTREEVHQAVAR 234
Query 181 LVADGP 186
++ GP
Sbjct 235 VI--GP 238
>gi|146310995|ref|YP_001176069.1| TetR family transcriptional regulator [Enterobacter sp. 638]
gi|145317871|gb|ABP60018.1| transcriptional regulator, TetR family [Enterobacter sp. 638]
Length=182
Score = 80.5 bits (197), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 51/183 (28%), Positives = 86/183 (47%), Gaps = 8/183 (4%)
Query 7 RRPRDPAGRRQAIVEAAERVIARQGLGGLSHRRVAAEANVPVGSTTYYFNDLDALREAAL 66
RRP DP RR+ I++A IA G+ ++HR++A A VP+GS TYYF +D+L E A
Sbjct 3 RRPNDPL-RRERILQATLETIAEHGIDAVTHRKIATCAGVPLGSMTYYFEGMDSLLEEAF 61
Query 67 AHAANASADLLAQWRSDLDKDRDLAATLARLTTVYLADQ----DRYRTLNELYMAAAHRP 122
+ D+ Q+ +TT+ + + + +LY + +P
Sbjct 62 ---TRFTCDMSQQYCDFFAGVTGPEMACESITTLIHSSEVTTPHNMELMYQLYALMSRKP 118
Query 123 ELQRLARLWPDGLLALLEPRIGRRAANAVTVFFDGATLHALITGTPLSTDELTDAIARLV 182
L+++ + W + LE A A+ F +G TLH + PLS D++ + R+
Sbjct 119 ALKKVMQDWMQTSQSTLEQWFDPVTARALDAFIEGMTLHFVTDRQPLSRDDIRRMVGRIA 178
Query 183 ADG 185
+
Sbjct 179 GEN 181
>gi|239986856|ref|ZP_04707520.1| TetR family transcriptional regulator [Streptomyces roseosporus
NRRL 11379]
gi|291443808|ref|ZP_06583198.1| ebrA repressor [Streptomyces roseosporus NRRL 15998]
gi|291346755|gb|EFE73659.1| ebrA repressor [Streptomyces roseosporus NRRL 15998]
Length=200
Score = 80.5 bits (197), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 73/197 (38%), Positives = 93/197 (48%), Gaps = 20/197 (10%)
Query 8 RPRDPAGRRQAIVEAAERVIARQGLGGLSHRRVAAEANVPVGSTTYYFNDLDALREAALA 67
R DP RR I++AA VIA G+ GLSHR VAAEA+VP+GSTTY+F LD L AAL
Sbjct 3 RRYDPE-RRTRIIDAALTVIAADGMAGLSHRTVAAEADVPLGSTTYHFASLDELLVAALR 61
Query 68 HA------ANASADLLAQWRSDLD------------KDRDLAATLARLTTVYLADQDRYR 109
A S+ L A+ + + LA L RL + A +
Sbjct 62 RCNENFVQALRSSGLFAEEAEEGGAGRGEGDAGQGAEGAGLAEELTRLLDRWFAGERGAI 121
Query 110 TLN-ELYMAAAHRPELQRLARLWPDGLLALLEPRIGRRAANAVTVFFDGATLHALITGTP 168
L ELY+AA RP L+ +A W +ALL R A A+ DG L L+TG
Sbjct 122 ELEYELYLAALRRPALRPVAAEWTTEAVALLSRRTDPETARALVALMDGVCLQVLLTGGT 181
Query 169 LSTDELTDAIARLVADG 185
+ R+VA G
Sbjct 182 FDAAYTRVMLERIVAGG 198
>gi|134103635|ref|YP_001109296.1| putative DeoR-type transcriptional regulator [Saccharopolyspora
erythraea NRRL 2338]
gi|291004829|ref|ZP_06562802.1| putative DeoR-type transcriptional regulator [Saccharopolyspora
erythraea NRRL 2338]
gi|133916258|emb|CAM06371.1| putative DeoR-type transcriptional regulator [Saccharopolyspora
erythraea NRRL 2338]
Length=201
Score = 80.5 bits (197), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 60/179 (34%), Positives = 90/179 (51%), Gaps = 7/179 (3%)
Query 19 IVEAAERVIARQGLGGLSHRRVAAEANVPVGSTTYYFNDLDALREAALAHAANASADLLA 78
IV+A RV+AR G+ G+SHR +A EA VP S YYF+ +D L A L + +
Sbjct 22 IVDATLRVVARDGIAGVSHRNIAREAGVPAASVGYYFDSIDDLLVATLLDSVEVLIAEID 81
Query 79 QWRSDLDKDRDLAATLARLTTVYLADQDRYRTL--NELYMAAAHRPELQRLARLWPDGLL 136
+ S++ D +AR+ + D+ R RTL ELY+ AA RP L+ AR W +
Sbjct 82 RMTSEVGSDEQWPGVVARMLA-RMIDEHRERTLAEYELYLLAARRPALRPAARRWIEVAT 140
Query 137 ALLEPRIGRRAANAVTVFF---DGATLHALITGTPLSTDELTDAIARLVADGPEQREVG 192
+ G +A+ FF DG L AL+ P + +EL ++ ++ G R +G
Sbjct 141 GYVNGGEGGD-PHAMRAFFAAIDGLVLQALVADEPPTAEELEASLRYVMQPGSYLRSLG 198
>gi|170768984|ref|ZP_02903437.1| transcriptional regulator, TetR family [Escherichia albertii
TW07627]
gi|170122056|gb|EDS90987.1| transcriptional regulator, TetR family [Escherichia albertii
TW07627]
Length=191
Score = 79.3 bits (194), Expect = 3e-13, Method: Compositional matrix adjust.
Identities = 49/179 (28%), Positives = 86/179 (49%), Gaps = 8/179 (4%)
Query 7 RRPRDPAGRRQAIVEAAERVIARQGLGGLSHRRVAAEANVPVGSTTYYFNDLDALREAAL 66
RR DP RR+ I+ A + G+ ++HR++A A VP+GS TYYF+ +D L A
Sbjct 2 RRANDPQ-RREKIIRATLEAVKLYGIHAVTHRKIAVLAQVPLGSMTYYFSGIDELLLEAF 60
Query 67 AHAANASADLLAQWRSDLDKDRDLAATLARLTTVYLADQ----DRYRTLNELYMAAAHRP 122
+ + Q+++ D D ++ +T + + Q + + +LY A+ +P
Sbjct 61 SRFTQTMS---LQYQTFFDDVSDASSACQAITEMIYSSQVATPNNMELMYQLYALASRKP 117
Query 123 ELQRLARLWPDGLLALLEPRIGRRAANAVTVFFDGATLHALITGTPLSTDELTDAIARL 181
+L+ + + W LE A A+ F +G TLH + PLS +E+ + R+
Sbjct 118 QLKTVMQNWMQRSQQTLEQWFEPGTARALDAFIEGMTLHFVTDCKPLSREEILKMVERV 176
>gi|297560633|ref|YP_003679607.1| TetR family transcriptional regulator [Nocardiopsis dassonvillei
subsp. dassonvillei DSM 43111]
gi|296845081|gb|ADH67101.1| transcriptional regulator, TetR family [Nocardiopsis dassonvillei
subsp. dassonvillei DSM 43111]
Length=184
Score = 79.3 bits (194), Expect = 3e-13, Method: Compositional matrix adjust.
Identities = 60/172 (35%), Positives = 83/172 (49%), Gaps = 7/172 (4%)
Query 5 SDRRPRDPAGRRQAIVEAAERVIARQGLGGLSHRRVAAEANVPVGSTTYYFNDLDALREA 64
SD R RRQA++EA RVI R G+ G+SHR V+ EA VP +TTYYF L L A
Sbjct 4 SDGRRLKGEQRRQALIEATLRVIERDGVAGVSHRTVSQEAGVPTSATTYYFTGLGDLLTA 63
Query 65 ALAHAANASADLLAQWRSDLDKDRDLAATLARLTTVYLADQDRYRTLNELYMAAAHRPEL 124
AL + ++ + + S D+ RDLA L+++ + D R EL++ AA +P L
Sbjct 64 ALTGVMDEDSERMRRMSSGGDRRRDLAELLSKVAS----DPGRLLAEYELFLLAARQPHL 119
Query 125 QRLARLWPDGLLALLEPRIGR--RAANAVTVFFDGATLHALITGTPLSTDEL 174
+ W + A R N V DG LH L++ DE
Sbjct 120 REATDRWLAAVSAFARCYTDDPVRVRNVAAV-IDGILLHTLLSDHKPDADEF 170
>gi|257057801|ref|YP_003135633.1| hypothetical protein Svir_38620 [Saccharomonospora viridis DSM
43017]
gi|256587673|gb|ACU98806.1| uncharacterized conserved protein [Saccharomonospora viridis
DSM 43017]
Length=186
Score = 78.2 bits (191), Expect = 7e-13, Method: Compositional matrix adjust.
Identities = 64/168 (39%), Positives = 85/168 (51%), Gaps = 15/168 (8%)
Query 15 RRQAIVEAAERVIARQGLGGLSHRRVAAEANVPVGSTTYYFNDLDALREAALAHAANASA 74
RRQ I+EA RVI R G+ G++HR VA EA VP STTY+F+ LD L A L A
Sbjct 15 RRQEIIEATLRVIERDGVAGVTHRTVAKEAGVPTTSTTYHFSSLDDLLIATLISCAR--- 71
Query 75 DLLAQWRSDLDKDRDLAATLARLTTVYLAD---QDRYRTL--NELYMAAAHRPELQRLAR 129
D+ + +D+ R + A LA+ R RT+ ELY+ AA RPEL+ AR
Sbjct 72 DMATEVYWMIDRARSRGSRGADEVANLLAEAIGPRRGRTMAEYELYLLAARRPELRPAAR 131
Query 130 LWPDGLLALLEPRIGRRAANAVTVFF---DGATLHALITGTPLSTDEL 174
W D L ++ + A VF DG + LI P + +EL
Sbjct 132 RWLDVLTSM----VRHDDEVAFRVFLAGIDGLLIQGLIDDEPPTAEEL 175
>gi|302531180|ref|ZP_07283522.1| predicted protein [Streptomyces sp. AA4]
gi|302440075|gb|EFL11891.1| predicted protein [Streptomyces sp. AA4]
Length=186
Score = 77.8 bits (190), Expect = 8e-13, Method: Compositional matrix adjust.
Identities = 64/168 (39%), Positives = 85/168 (51%), Gaps = 15/168 (8%)
Query 15 RRQAIVEAAERVIARQGLGGLSHRRVAAEANVPVGSTTYYFNDLDALREAALAHAANASA 74
RR I+EA RVI R G+ G++HR VAAEA VP STTY+F+ LD L A L A
Sbjct 15 RRTEIIEATLRVIERDGVAGVTHRTVAAEAGVPTTSTTYHFSSLDDLLVATLISCAR--- 71
Query 75 DLLAQWRSDLDKDRDLAATLARLTTVYLADQ---DRYRTL--NELYMAAAHRPELQRLAR 129
D+ + +D+ R + A LA+ R RT+ ELY+ AA +PEL+ AR
Sbjct 72 DMATEVYWMIDRARSRGSRGAEEVAGLLAEALGPRRGRTMAEYELYLLAARKPELRPAAR 131
Query 130 LWPDGLLALLEPRIGRRAANAVTVFF---DGATLHALITGTPLSTDEL 174
W D L ++ + A VF DG + LI P S +EL
Sbjct 132 RWLDVLTSM----VRHDDEVAFRVFLAGIDGLLIQGLIDDEPPSAEEL 175
>gi|283784609|ref|YP_003364474.1| TetR family transcriptional regulator [Citrobacter rodentium
ICC168]
gi|282948063|emb|CBG87628.1| TetR-family transcriptional regulator [Citrobacter rodentium
ICC168]
Length=193
Score = 77.8 bits (190), Expect = 8e-13, Method: Compositional matrix adjust.
Identities = 56/189 (30%), Positives = 92/189 (49%), Gaps = 12/189 (6%)
Query 7 RRPRDPAGRRQAIVEAAERVIARQGLGGLSHRRVAAEANVPVGSTTYYFNDLDALREAAL 66
RR DP RR+ I+ A + G+ ++HR++AA A+VP+GS TYYF+ +D L L
Sbjct 2 RRANDPQ-RREKIITATLEAVKEHGIHAVTHRKIAAIADVPLGSLTYYFSGIDEL----L 56
Query 67 AHAANASADLL-AQWRSDLDKDRDLAATLARLTTVYLADQ----DRYRTLNELYMAAAHR 121
+ A N D++ AQ+++ D + + + Q + + +LY A+ +
Sbjct 57 SEAFNCFTDVMSAQYQAFFSGVTDAQGACQAIAEMIDSSQVTTPENMALMYQLYAFASRK 116
Query 122 PELQRLARLWPDGLLALLEPRIGRRAANAVTVFFDGATLHALITGTPLSTDELTDAIARL 181
P L+ + + W LE A A+ F +G TLH + PLS +E+ + R+
Sbjct 117 PALKTVMQNWMQRSQQTLEQWFDPGTARALDAFIEGMTLHFVTDRAPLSREEILLMVRRV 176
Query 182 VADGPEQRE 190
G E RE
Sbjct 177 A--GEEVRE 183
>gi|336249446|ref|YP_004593156.1| putative DeoR-type transcriptional regulator [Enterobacter aerogenes
KCTC 2190]
gi|334735502|gb|AEG97877.1| putative DeoR-type transcriptional regulator [Enterobacter aerogenes
KCTC 2190]
Length=184
Score = 77.8 bits (190), Expect = 9e-13, Method: Compositional matrix adjust.
Identities = 52/182 (29%), Positives = 87/182 (48%), Gaps = 8/182 (4%)
Query 7 RRPRDPAGRRQAIVEAAERVIARQGLGGLSHRRVAAEANVPVGSTTYYFNDLDALREAAL 66
RRP DP RR+ I++A IA G+ ++HR++A+ A VP+GS TYYF+ ++AL E A
Sbjct 3 RRPNDPQ-RRERILQATLDTIAAHGIHAVTHRKIASCAGVPLGSLTYYFSGIEALIEEAF 61
Query 67 AHAANASADLLAQWRSDLD----KDRDLAATLARLTTVYLADQDRYRTLNELYMAAAHRP 122
N + ++ AQ++ D + + A + + + + +LY + RP
Sbjct 62 ---RNFTVEMSAQYQQFFDGVGSRQQACDAIAELIFSAQVTTARNMELMYQLYAFCSSRP 118
Query 123 ELQRLARLWPDGLLALLEPRIGRRAANAVTVFFDGATLHALITGTPLSTDELTDAIARLV 182
L+ + + W LE A + F +G TLH + PLS + + RL
Sbjct 119 ALKTVMQSWMLRSQQTLEQWFEPATARGLDAFIEGMTLHFVTDSAPLSKAAIRLMVGRLA 178
Query 183 AD 184
+
Sbjct 179 GE 180
>gi|324112718|gb|EGC06694.1| tetR family protein regulatory protein [Escherichia fergusonii
B253]
Length=179
Score = 77.8 bits (190), Expect = 9e-13, Method: Compositional matrix adjust.
Identities = 45/176 (26%), Positives = 83/176 (48%), Gaps = 2/176 (1%)
Query 7 RRPRDPAGRRQAIVEAAERVIARQGLGGLSHRRVAAEANVPVGSTTYYFNDLDALREAAL 66
RR DP RR+ I+ A IA G+ ++HR++A A VP+GS TYYF+ +D L A
Sbjct 2 RRSNDPQ-RREKIIAATLEAIATHGIHAVTHRKIAIIAQVPLGSLTYYFSGIDELLTIAF 60
Query 67 AHAANASADLLAQWRSDLDKDRDLAATLARLT-TVYLADQDRYRTLNELYMAAAHRPELQ 125
+ + + + + + + + + + ++ + +LY A+ +P L+
Sbjct 61 RRFTEIMTEQYQSFFTGVSEPIEACEAITEMIHSAQITTPEKMALMYQLYAFASRKPALK 120
Query 126 RLARLWPDGLLALLEPRIGRRAANAVTVFFDGATLHALITGTPLSTDELTDAIARL 181
++ + W L+ A A+ F +G TLH + PL+ DE+ + R+
Sbjct 121 KVMQNWMHSSQQTLQQWFDPDTARALDAFIEGMTLHFVTDSKPLTRDEILKMVKRI 176
>gi|134101872|ref|YP_001107533.1| TetR family transcriptional regulator [Saccharopolyspora erythraea
NRRL 2338]
gi|291008598|ref|ZP_06566571.1| TetR family transcriptional regulator [Saccharopolyspora erythraea
NRRL 2338]
gi|133914495|emb|CAM04608.1| TetR-family transcriptional regulator [Saccharopolyspora erythraea
NRRL 2338]
Length=295
Score = 77.4 bits (189), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 70/184 (39%), Positives = 96/184 (53%), Gaps = 6/184 (3%)
Query 8 RPRDPAGRRQAIVEAAERVIARQGLGGLSHRRVAAEANVPVGSTTYYFNDLDALREAALA 67
RP+DPA RR+ I AA V+A +G+ L+HR VAA A VP+GSTTYYF +LD L AL
Sbjct 115 RPKDPA-RRERIARAAISVVAERGIEKLTHRAVAAAAGVPLGSTTYYFANLDDLLAEALR 173
Query 68 HAANASADLLAQWRSDLDKDRDLAATLARLTTVYLADQDRYRTL--NELYMAAAHRPELQ 125
AA L +W LD D AA LA L YL + R RT+ +ELY+AA HRP L
Sbjct 174 QAAGDDVAQLREWARGLDPSADFAAALADLVLHYLGPE-RSRTVVEHELYVAALHRPALA 232
Query 126 RLARLWPDGLLALLEPRIGRRAANAVTVFFDGATLHALITGTPLSTDELTDAIARLVADG 185
++ W L ++ F G L ++ + + DE+ R++ G
Sbjct 233 HVSTEWDAALAEEFTAHTDPVTGKVLSALFCGLLLQGVVRESVPTRDEIETLFRRVL--G 290
Query 186 PEQR 189
P ++
Sbjct 291 PAEK 294
>gi|333955922|gb|EGL73629.1| hypothetical protein CSE899_05067 [Cronobacter sakazakii E899]
Length=181
Score = 77.4 bits (189), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 58/180 (33%), Positives = 89/180 (50%), Gaps = 12/180 (6%)
Query 8 RPRDPAGRRQAIVEAAERVIARQGLGGLSHRRVAAEANVPVGSTTYYFNDLDALREAALA 67
R DP RR+ I+EA IA G ++HR++A EA VP+GS TYYF L+AL A
Sbjct 4 RQNDP-QRRERILEATLACIATHGFHHITHRKIALEAGVPLGSVTYYFTSLEALLAEAFT 62
Query 68 HAANASAD----LLAQWRSDLDKDRDLAATL--ARLTTVYLADQDRYRTLNELYMAAAHR 121
A + + L+AQ +S + L A + A++TT + + +LY A+ +
Sbjct 63 RFAESMSRQYQALMAQAQSREEACEALTALICGAQVTT-----PENMELMYQLYAYASRQ 117
Query 122 PELQRLARLWPDGLLALLEPRIGRRAANAVTVFFDGATLHALITGTPLSTDELTDAIARL 181
P+L+ + + W LE A A+ F +G TLH ++ PL E+ + RL
Sbjct 118 PQLKIIMQDWMRRSQQTLETWFDPATARALDAFVEGMTLHYVVDREPLKEAEIRVIVLRL 177
>gi|345014301|ref|YP_004816655.1| TetR family transcriptional regulator [Streptomyces violaceusniger
Tu 4113]
gi|344040650|gb|AEM86375.1| transcriptional regulator, TetR family [Streptomyces violaceusniger
Tu 4113]
Length=189
Score = 77.4 bits (189), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 65/173 (38%), Positives = 88/173 (51%), Gaps = 8/173 (4%)
Query 15 RRQAIVEAAERVIARQGLGGLSHRRVAAEANVPVGSTTYYFNDLDALREAALAHAANASA 74
RRQ I++AA V+ G+GGL HR VAA A+VP+GSTTY+F LD L AAL +A
Sbjct 9 RRQRIIDAAAAVVRESGIGGLGHRAVAAAADVPLGSTTYHFATLDDLLIAALRQ---INA 65
Query 75 DLLAQ---WRSDLDKDRDLAATLAR-LTTVYLADQDRYRTLNELYMAAAHRPELQRLARL 130
+ LA+ W +D A LAR L + D+ R ELY AA L+ LA
Sbjct 66 EWLAEVRHWVEGVDPAAPPADELARWLGEQFTGDRARMELEYELYFAALRHEGLRPLAAE 125
Query 131 WPDGLLALLEPRI-GRRAANAVTVFFDGATLHALITGTPLSTDELTDAIARLV 182
D + +L + A AV DG TL L+ P + + A+AR++
Sbjct 126 CLDEMARMLTRLVPDATTARAVVALIDGLTLQVLLADRPYDREGTSAALARIM 178
Lambda K H
0.319 0.132 0.380
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 220408776486
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
Posted date: Sep 5, 2011 4:36 AM
Number of letters in database: 5,219,829,388
Number of sequences in database: 15,229,318
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40