BLASTP 2.2.25+
Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
15,229,318 sequences; 5,219,829,388 total letters
Query= Rv3076
Length=158
Score E
Sequences producing significant alignments: (Bits) Value
gi|15610213|ref|NP_217592.1| hypothetical protein Rv3076 [Mycoba... 316 6e-85
gi|289553133|ref|ZP_06442343.1| conserved hypothetical protein [... 313 5e-84
gi|308232331|ref|ZP_07415722.2| hypothetical protein TMAG_03249 ... 304 3e-81
gi|289763255|ref|ZP_06522633.1| conserved hypothetical protein [... 286 5e-76
gi|118618759|ref|YP_907091.1| hypothetical protein MUL_3456 [Myc... 194 3e-48
gi|183981594|ref|YP_001849885.1| hypothetical protein MMAR_1578 ... 184 3e-45
gi|296166343|ref|ZP_06848779.1| cyclase/dehydratase [Mycobacteri... 166 1e-39
gi|342857444|ref|ZP_08714100.1| hypothetical protein MCOL_01170 ... 164 5e-39
gi|118469635|ref|YP_885677.1| cyclase/dehydrase [Mycobacterium s... 152 2e-35
gi|240168677|ref|ZP_04747336.1| hypothetical protein MkanA1_0515... 136 1e-30
gi|126433509|ref|YP_001069200.1| cyclase/dehydrase [Mycobacteriu... 124 7e-27
gi|108797869|ref|YP_638066.1| cyclase/dehydrase [Mycobacterium s... 117 4e-25
gi|120405227|ref|YP_955056.1| cyclase/dehydrase [Mycobacterium v... 111 3e-23
gi|145222960|ref|YP_001133638.1| hypothetical protein Mflv_2373 ... 97.8 5e-19
gi|213649223|ref|ZP_03379276.1| hypothetical protein SentesTy_19... 65.9 2e-09
gi|333992691|ref|YP_004525305.1| hypothetical protein JDM601_405... 53.9 7e-06
gi|254438318|ref|ZP_05051812.1| hypothetical protein OA307_3188 ... 47.4 7e-04
gi|217976669|ref|YP_002360816.1| MxaD protein [Methylocella silv... 46.6 0.001
gi|254440310|ref|ZP_05053804.1| hypothetical protein OA307_5180 ... 44.7 0.005
gi|220914883|ref|YP_002490191.1| MxaD protein, putative [Methylo... 43.1 0.014
gi|119510311|ref|ZP_01629447.1| cyclase/dehydrase-like protein [... 42.7 0.018
gi|342859685|ref|ZP_08716338.1| hypothetical protein MCOL_12418 ... 42.7 0.019
gi|312140175|ref|YP_004007511.1| hypothetical protein REQ_28120 ... 42.4 0.026
gi|340776242|ref|ZP_08696185.1| polyketide cyclase/dehydrase [Ac... 41.6 0.042
gi|302869153|ref|YP_003837790.1| polyketide cyclase/dehydrase [M... 41.2 0.047
gi|158335414|ref|YP_001516586.1| hypothetical protein AM1_2259 [... 41.2 0.049
gi|148553952|ref|YP_001261534.1| hypothetical protein Swit_1029 ... 41.2 0.049
gi|170690404|ref|ZP_02881571.1| hypothetical protein BgramDRAFT_... 40.8 0.064
gi|17228347|ref|NP_484895.1| hypothetical protein all0852 [Nosto... 40.4 0.091
gi|75910653|ref|YP_324949.1| cyclase/dehydrase [Anabaena variabi... 40.4 0.094
gi|288916002|ref|ZP_06410384.1| hypothetical protein FrEUN1fDRAF... 40.0 0.12
gi|338708509|ref|YP_004662710.1| polyketide cyclase/dehydrase [Z... 39.7 0.13
gi|254775258|ref|ZP_05216774.1| hypothetical protein MaviaA2_113... 39.7 0.15
gi|145595888|ref|YP_001160185.1| cyclase/dehydrase [Salinispora ... 39.7 0.16
gi|296167249|ref|ZP_06849654.1| conserved hypothetical protein [... 39.7 0.17
gi|119474947|ref|ZP_01615300.1| hypothetical protein GP2143_1404... 39.7 0.17
gi|297195733|ref|ZP_06913131.1| conserved hypothetical protein [... 39.7 0.17
gi|41407744|ref|NP_960580.1| hypothetical protein MAP1646c [Myco... 39.3 0.18
gi|118466784|ref|YP_881966.1| hypothetical protein MAV_2778 [Myc... 39.3 0.19
gi|330469479|ref|YP_004407222.1| polyketide cyclase/dehydrase [V... 38.9 0.24
gi|169627930|ref|YP_001701579.1| hypothetical protein MAB_0831 [... 38.9 0.26
gi|296115474|ref|ZP_06834107.1| hypothetical protein GXY_06810 [... 38.5 0.29
gi|271965449|ref|YP_003339645.1| hypothetical protein Sros_3994 ... 38.5 0.30
gi|91786479|ref|YP_547431.1| carbon monoxide dehydrogenase subun... 38.5 0.35
gi|159039150|ref|YP_001538403.1| cyclase/dehydrase [Salinispora ... 38.1 0.42
gi|334132818|ref|ZP_08506574.1| MxaD protein [Methyloversatilis ... 38.1 0.46
gi|311105019|ref|YP_003977872.1| polyketide cyclase/dehydrase fa... 37.7 0.56
gi|311695709|gb|ADP98582.1| conserved hypothetical protein [Mari... 37.7 0.57
gi|134099544|ref|YP_001105205.1| cyclase/dehydrase [Saccharopoly... 37.7 0.57
gi|345013238|ref|YP_004815592.1| polyketide cyclase/dehydrase [S... 37.4 0.81
>gi|15610213|ref|NP_217592.1| hypothetical protein Rv3076 [Mycobacterium tuberculosis H37Rv]
gi|15842646|ref|NP_337683.1| hypothetical protein MT3161 [Mycobacterium tuberculosis CDC1551]
gi|31794255|ref|NP_856748.1| hypothetical protein Mb3103 [Mycobacterium bovis AF2122/97]
68 more sequence titles
Length=158
Score = 316 bits (810), Expect = 6e-85, Method: Compositional matrix adjust.
Identities = 158/158 (100%), Positives = 158/158 (100%), Gaps = 0/158 (0%)
Query 1 MVLDGVVSDTRRSRTIAARQQTIWDVLADFGSLSSWVEGVDHSCVLNHGPDGGALGSTRR 60
MVLDGVVSDTRRSRTIAARQQTIWDVLADFGSLSSWVEGVDHSCVLNHGPDGGALGSTRR
Sbjct 1 MVLDGVVSDTRRSRTIAARQQTIWDVLADFGSLSSWVEGVDHSCVLNHGPDGGALGSTRR 60
Query 61 VQVGRNTLVERVIEFDPPTTLAYRIEGLPARLRKVTNRWTLRPADPVGAVTVVTLTSTIE 120
VQVGRNTLVERVIEFDPPTTLAYRIEGLPARLRKVTNRWTLRPADPVGAVTVVTLTSTIE
Sbjct 61 VQVGRNTLVERVIEFDPPTTLAYRIEGLPARLRKVTNRWTLRPADPVGAVTVVTLTSTIE 120
Query 121 IGGNPLARLAELVVGRAMAKRSNTMLAGLAQRLEDKHG 158
IGGNPLARLAELVVGRAMAKRSNTMLAGLAQRLEDKHG
Sbjct 121 IGGNPLARLAELVVGRAMAKRSNTMLAGLAQRLEDKHG 158
>gi|289553133|ref|ZP_06442343.1| conserved hypothetical protein [Mycobacterium tuberculosis KZN
605]
gi|289437765|gb|EFD20258.1| conserved hypothetical protein [Mycobacterium tuberculosis KZN
605]
Length=157
Score = 313 bits (802), Expect = 5e-84, Method: Compositional matrix adjust.
Identities = 156/157 (99%), Positives = 157/157 (100%), Gaps = 0/157 (0%)
Query 2 VLDGVVSDTRRSRTIAARQQTIWDVLADFGSLSSWVEGVDHSCVLNHGPDGGALGSTRRV 61
+LDGVVSDTRRSRTIAARQQTIWDVLADFGSLSSWVEGVDHSCVLNHGPDGGALGSTRRV
Sbjct 1 MLDGVVSDTRRSRTIAARQQTIWDVLADFGSLSSWVEGVDHSCVLNHGPDGGALGSTRRV 60
Query 62 QVGRNTLVERVIEFDPPTTLAYRIEGLPARLRKVTNRWTLRPADPVGAVTVVTLTSTIEI 121
QVGRNTLVERVIEFDPPTTLAYRIEGLPARLRKVTNRWTLRPADPVGAVTVVTLTSTIEI
Sbjct 61 QVGRNTLVERVIEFDPPTTLAYRIEGLPARLRKVTNRWTLRPADPVGAVTVVTLTSTIEI 120
Query 122 GGNPLARLAELVVGRAMAKRSNTMLAGLAQRLEDKHG 158
GGNPLARLAELVVGRAMAKRSNTMLAGLAQRLEDKHG
Sbjct 121 GGNPLARLAELVVGRAMAKRSNTMLAGLAQRLEDKHG 157
>gi|308232331|ref|ZP_07415722.2| hypothetical protein TMAG_03249 [Mycobacterium tuberculosis SUMu001]
gi|308372419|ref|ZP_07428606.2| hypothetical protein TMDG_03316 [Mycobacterium tuberculosis SUMu004]
gi|308375982|ref|ZP_07445724.2| hypothetical protein TMGG_02616 [Mycobacterium tuberculosis SUMu007]
gi|308378183|ref|ZP_07481817.2| hypothetical protein TMIG_02582 [Mycobacterium tuberculosis SUMu009]
gi|308214273|gb|EFO73672.1| hypothetical protein TMAG_03249 [Mycobacterium tuberculosis SUMu001]
gi|308333295|gb|EFP22146.1| hypothetical protein TMDG_03316 [Mycobacterium tuberculosis SUMu004]
gi|308344633|gb|EFP33484.1| hypothetical protein TMGG_02616 [Mycobacterium tuberculosis SUMu007]
gi|308353306|gb|EFP42157.1| hypothetical protein TMIG_02582 [Mycobacterium tuberculosis SUMu009]
Length=152
Score = 304 bits (779), Expect = 3e-81, Method: Compositional matrix adjust.
Identities = 151/152 (99%), Positives = 152/152 (100%), Gaps = 0/152 (0%)
Query 7 VSDTRRSRTIAARQQTIWDVLADFGSLSSWVEGVDHSCVLNHGPDGGALGSTRRVQVGRN 66
+SDTRRSRTIAARQQTIWDVLADFGSLSSWVEGVDHSCVLNHGPDGGALGSTRRVQVGRN
Sbjct 1 MSDTRRSRTIAARQQTIWDVLADFGSLSSWVEGVDHSCVLNHGPDGGALGSTRRVQVGRN 60
Query 67 TLVERVIEFDPPTTLAYRIEGLPARLRKVTNRWTLRPADPVGAVTVVTLTSTIEIGGNPL 126
TLVERVIEFDPPTTLAYRIEGLPARLRKVTNRWTLRPADPVGAVTVVTLTSTIEIGGNPL
Sbjct 61 TLVERVIEFDPPTTLAYRIEGLPARLRKVTNRWTLRPADPVGAVTVVTLTSTIEIGGNPL 120
Query 127 ARLAELVVGRAMAKRSNTMLAGLAQRLEDKHG 158
ARLAELVVGRAMAKRSNTMLAGLAQRLEDKHG
Sbjct 121 ARLAELVVGRAMAKRSNTMLAGLAQRLEDKHG 152
>gi|289763255|ref|ZP_06522633.1| conserved hypothetical protein [Mycobacterium tuberculosis GM
1503]
gi|289710761|gb|EFD74777.1| conserved hypothetical protein [Mycobacterium tuberculosis GM
1503]
Length=186
Score = 286 bits (733), Expect = 5e-76, Method: Compositional matrix adjust.
Identities = 146/152 (97%), Positives = 147/152 (97%), Gaps = 1/152 (0%)
Query 6 VVSDTRRSRTIAARQQTIWDVLADFGSLSSWVEGVDHSCVLNHGPDGGALGSTRRVQVGR 65
+VSDTRRSRTIAARQQTIWDVLADFGSLSSWVEGVDHSCVLNHGPDGGALGSTRRVQVGR
Sbjct 1 MVSDTRRSRTIAARQQTIWDVLADFGSLSSWVEGVDHSCVLNHGPDGGALGSTRRVQVGR 60
Query 66 NTLVERVIEFDPPTTLAYRIEGLPARLRKVTNRWTLRPADPVGAVTVVTLTSTIEIGGNP 125
NTLVERVIEFDPPTTLAYRIEGLPARLRKVTNRWTLRPADPVGAVTVVTLTSTIEIGGNP
Sbjct 61 NTLVERVIEFDPPTTLAYRIEGLPARLRKVTNRWTLRPADPVGAVTVVTLTSTIEIGGNP 120
Query 126 LARLAELVVGRAMAKRSNTMLAGLAQR-LEDK 156
LARLAELVVGRAMAKRSNTMLAG LEDK
Sbjct 121 LARLAELVVGRAMAKRSNTMLAGPGNNGLEDK 152
>gi|118618759|ref|YP_907091.1| hypothetical protein MUL_3456 [Mycobacterium ulcerans Agy99]
gi|118570869|gb|ABL05620.1| conserved hypothetical protein [Mycobacterium ulcerans Agy99]
Length=149
Score = 194 bits (493), Expect = 3e-48, Method: Compositional matrix adjust.
Identities = 95/152 (63%), Positives = 117/152 (77%), Gaps = 3/152 (1%)
Query 7 VSDTRRSRTIAARQQTIWDVLADFGSLSSWVEGVDHSCVLNHGPDGGALGSTRRVQVGRN 66
++D RSRTI A Q IW+VLADFG+LS+W +G+DHSCVLN GPDG +G+TRRVQVGRN
Sbjct 1 MADISRSRTIVAEPQAIWNVLADFGALSTWADGIDHSCVLNEGPDGEPVGTTRRVQVGRN 60
Query 67 TLVERVIEFDPPTTLAYRIEGLPARLRKVTNRWTLRPADPVGAVTVVTLTSTIEIGGNPL 126
TLVER+ FDPPT+LAY IEGLP RLRKV N W LR + G T+V LTST+E+G + L
Sbjct 61 TLVERITAFDPPTSLAYDIEGLPNRLRKVANHWRLRRS---GNATIVDLTSTVEVGTSRL 117
Query 127 ARLAELVVGRAMAKRSNTMLAGLAQRLEDKHG 158
A++AE V R +A++S+ MLAGLA RLE H
Sbjct 118 AQMAERVALRVLAQQSDAMLAGLASRLEKTHA 149
>gi|183981594|ref|YP_001849885.1| hypothetical protein MMAR_1578 [Mycobacterium marinum M]
gi|183174920|gb|ACC40030.1| conserved hypothetical protein [Mycobacterium marinum M]
Length=139
Score = 184 bits (468), Expect = 3e-45, Method: Compositional matrix adjust.
Identities = 90/141 (64%), Positives = 109/141 (78%), Gaps = 3/141 (2%)
Query 18 ARQQTIWDVLADFGSLSSWVEGVDHSCVLNHGPDGGALGSTRRVQVGRNTLVERVIEFDP 77
A Q IW+VLADFG+LS+W +G+DHSCVLN GPDG +G+TRRVQVGRNTLVER+ FDP
Sbjct 2 AEPQAIWNVLADFGALSTWADGIDHSCVLNEGPDGEPVGTTRRVQVGRNTLVERITAFDP 61
Query 78 PTTLAYRIEGLPARLRKVTNRWTLRPADPVGAVTVVTLTSTIEIGGNPLARLAELVVGRA 137
PT+LAY IEGLP RLRKV N W LR + G T+V LTST+E+G + LA++AE V R
Sbjct 62 PTSLAYDIEGLPNRLRKVANHWRLRRS---GNATIVELTSTVEVGTSRLAQMAERVALRV 118
Query 138 MAKRSNTMLAGLAQRLEDKHG 158
+AK+S+ MLAGLA RLE H
Sbjct 119 LAKQSDAMLAGLASRLEKTHA 139
>gi|296166343|ref|ZP_06848779.1| cyclase/dehydratase [Mycobacterium parascrofulaceum ATCC BAA-614]
gi|295898306|gb|EFG77876.1| cyclase/dehydratase [Mycobacterium parascrofulaceum ATCC BAA-614]
Length=152
Score = 166 bits (420), Expect = 1e-39, Method: Compositional matrix adjust.
Identities = 90/151 (60%), Positives = 110/151 (73%), Gaps = 0/151 (0%)
Query 7 VSDTRRSRTIAARQQTIWDVLADFGSLSSWVEGVDHSCVLNHGPDGGALGSTRRVQVGRN 66
++D R+RTIAAR IW+ LADFGS+SSW VDHSC+L GP GG G+ RRVQV R+
Sbjct 1 MADIHRTRTIAARIGDIWETLADFGSISSWAGNVDHSCILLPGPGGGVPGTVRRVQVKRD 60
Query 67 TLVERVIEFDPPTTLAYRIEGLPARLRKVTNRWTLRPADPVGAVTVVTLTSTIEIGGNPL 126
L+ERV EFDPP L Y IEGLP+RLR+V NRWTL A G T VTLTST+EIG P+
Sbjct 61 ALLERVTEFDPPRALGYDIEGLPSRLRRVANRWTLATAGEAGLTTRVTLTSTVEIGPRPV 120
Query 127 ARLAELVVGRAMAKRSNTMLAGLAQRLEDKH 157
+LAE V+ R +A++S+ MLAGLA RLE +
Sbjct 121 QKLAEEVLCRFLARQSDAMLAGLANRLEHAY 151
>gi|342857444|ref|ZP_08714100.1| hypothetical protein MCOL_01170 [Mycobacterium colombiense CECT
3035]
gi|342134777|gb|EGT87943.1| hypothetical protein MCOL_01170 [Mycobacterium colombiense CECT
3035]
Length=153
Score = 164 bits (414), Expect = 5e-39, Method: Compositional matrix adjust.
Identities = 85/146 (59%), Positives = 108/146 (74%), Gaps = 1/146 (0%)
Query 11 RRSRTIAARQQTIWDVLADFGSLSSWVEGVDHSCVLNHGPDGGALGSTRRVQVGRNTLVE 70
+R+RTIAAR IW+VLADFGS+S+W VDHSC+L+ G +G +G+ RRVQV R+ LVE
Sbjct 5 QRTRTIAARVDDIWNVLADFGSISAWAGNVDHSCILHAGRNGQPVGTARRVQVKRDALVE 64
Query 71 RVIEFDPPTTLAYRIEGLPARLRKVTNRWTLRPADPVGA-VTVVTLTSTIEIGGNPLARL 129
R+ EF+PP LAY I+GLP RLR+V+NRWTL A T VTLTST+EIG P RL
Sbjct 65 RITEFEPPRALAYDIDGLPRRLRRVSNRWTLAAAAGAAVPETRVTLTSTVEIGPRPTHRL 124
Query 130 AELVVGRAMAKRSNTMLAGLAQRLED 155
AE ++ R +A++ + MLAGLA RLED
Sbjct 125 AERILCRFLARQFDAMLAGLANRLED 150
>gi|118469635|ref|YP_885677.1| cyclase/dehydrase [Mycobacterium smegmatis str. MC2 155]
gi|118170922|gb|ABK71818.1| cyclase/dehydrase superfamily protein [Mycobacterium smegmatis
str. MC2 155]
Length=145
Score = 152 bits (384), Expect = 2e-35, Method: Compositional matrix adjust.
Identities = 82/142 (58%), Positives = 103/142 (73%), Gaps = 6/142 (4%)
Query 12 RSRTIAARQQTIWDVLADFGSLSSWVEGVDHSCVLNHGPDGGALGSTRRVQVGRNTLVER 71
RSR I A QQ IWDVLADFG+LSSWV+ +DHSCVLN P+ LG+TRRVQVGR LVER
Sbjct 6 RSRVIPAPQQAIWDVLADFGALSSWVDKIDHSCVLNAHPE--VLGTTRRVQVGRTVLVER 63
Query 72 VIEFDPPTTLAYRIEGLPARLRKVTNRWTLRPADPVGAVTVVTLTSTIEIGGNPLARLAE 131
+ E+ P+TLAY IEGLPA + ++TNRWTLRPA G T VT+TST++ G + +
Sbjct 64 ITEYREPSTLAYAIEGLPAWMGRLTNRWTLRPA---GVGTEVTVTSTVDPAGFA-SLVTS 119
Query 132 LVVGRAMAKRSNTMLAGLAQRL 153
V R +AK+S+ ML GLA+ +
Sbjct 120 AVTARVLAKQSDAMLDGLARTM 141
>gi|240168677|ref|ZP_04747336.1| hypothetical protein MkanA1_05150 [Mycobacterium kansasii ATCC
12478]
Length=114
Score = 136 bits (342), Expect = 1e-30, Method: Compositional matrix adjust.
Identities = 75/114 (66%), Positives = 88/114 (78%), Gaps = 0/114 (0%)
Query 45 VLNHGPDGGALGSTRRVQVGRNTLVERVIEFDPPTTLAYRIEGLPARLRKVTNRWTLRPA 104
+LNHGP GG +G+TRRVQVG N LVER+ EF+PPT L Y IEGLP RLRKV N WTLRP+
Sbjct 1 MLNHGPGGGPVGTTRRVQVGSNALVERITEFEPPTRLTYDIEGLPPRLRKVANCWTLRPS 60
Query 105 DPVGAVTVVTLTSTIEIGGNPLARLAELVVGRAMAKRSNTMLAGLAQRLEDKHG 158
P GA TVV+LTST+E+G AR+AE V R +AK+S MLAGLA RLE+ HG
Sbjct 61 GPAGAATVVSLTSTVEVGDGKPARMAEWVALRVLAKQSEAMLAGLAHRLENMHG 114
>gi|126433509|ref|YP_001069200.1| cyclase/dehydrase [Mycobacterium sp. JLS]
gi|126233309|gb|ABN96709.1| cyclase/dehydrase [Mycobacterium sp. JLS]
Length=150
Score = 124 bits (310), Expect = 7e-27, Method: Compositional matrix adjust.
Identities = 78/153 (51%), Positives = 102/153 (67%), Gaps = 5/153 (3%)
Query 6 VVSDTRRSRTIAARQQTIWDVLADFGSLSSWVEGVDHSCVLNHGPDGGALGSTRRVQVGR 65
+V+ R RT+ A Q +W++LADFG++ W++GVDHSC+L DG +G+ RRVQ+GR
Sbjct 1 MVAQISRRRTMRADPQQVWEMLADFGAIGQWLDGVDHSCILTTNADG-PVGTARRVQMGR 59
Query 66 NTLVERVIEFDPPTTLAYRIEGLPARLRKVTNRWTLRPADPVGAVTVVTLTSTIEIGGNP 125
TLVE + EFD PTTLAY I GLP LR NRWTLR AD G+ T VTLT+T+++G
Sbjct 60 MTLVETITEFDAPTTLAYDIVGLPRWLRHFNNRWTLR-AD--GSATAVTLTTTVDLGPGR 116
Query 126 LARLAELVVGRAMAK-RSNTMLAGLAQRLEDKH 157
LA +V ++K S+TMLA LA R E H
Sbjct 117 TRELAARLVCLLLSKMSSDTMLAALATRSECAH 149
>gi|108797869|ref|YP_638066.1| cyclase/dehydrase [Mycobacterium sp. MCS]
gi|119866963|ref|YP_936915.1| cyclase/dehydrase [Mycobacterium sp. KMS]
gi|108768288|gb|ABG07010.1| cyclase/dehydrase [Mycobacterium sp. MCS]
gi|119693052|gb|ABL90125.1| cyclase/dehydrase [Mycobacterium sp. KMS]
Length=150
Score = 117 bits (294), Expect = 4e-25, Method: Compositional matrix adjust.
Identities = 80/153 (53%), Positives = 102/153 (67%), Gaps = 5/153 (3%)
Query 6 VVSDTRRSRTIAARQQTIWDVLADFGSLSSWVEGVDHSCVLNHGPDGGALGSTRRVQVGR 65
+V+ R RT+ A Q +W+VLADFG++ W+ GVDHSC+L DG +G+ RRVQ+GR
Sbjct 1 MVAQLSRRRTMRADPQQVWEVLADFGAIGQWLSGVDHSCILTTNADG-PVGTARRVQMGR 59
Query 66 NTLVERVIEFDPPTTLAYRIEGLPARLRKVTNRWTLRPADPVGAVTVVTLTSTIEIGGNP 125
TLVE + EFD PTTLAY I GLP LR NRWTLR AD G+ T VTLT+T+++G
Sbjct 60 MTLVETITEFDAPTTLAYDIVGLPRWLRHFNNRWTLR-AD--GSATAVTLTTTVDLGPGR 116
Query 126 LARLAELVVGRAMAK-RSNTMLAGLAQRLEDKH 157
LA L+V ++K S+TMLA LA R E H
Sbjct 117 TRELAALLVCLLLSKMSSDTMLAALATRSECAH 149
>gi|120405227|ref|YP_955056.1| cyclase/dehydrase [Mycobacterium vanbaalenii PYR-1]
gi|119958045|gb|ABM15050.1| cyclase/dehydrase [Mycobacterium vanbaalenii PYR-1]
Length=153
Score = 111 bits (278), Expect = 3e-23, Method: Compositional matrix adjust.
Identities = 68/153 (45%), Positives = 92/153 (61%), Gaps = 3/153 (1%)
Query 2 VLDGVVSDTRRSRTIAARQQTIWDVLADFGSLSSWVEGVDHSCVLNHGPDGGALGSTRRV 61
+L+ V++ RSRT++A IW LADFGSLS+W +G+DHSC+LN +G TRR+
Sbjct 1 MLNEAVAEVSRSRTVSAESAAIWARLADFGSLSAWADGIDHSCLLNGDDHPEPVGLTRRI 60
Query 62 QVGRNTLVERVIEFDPPTTLAYRIEGLPARLRKVTNRWTLRPADPVGAVTVVTLTSTIEI 121
Q GR+T VE ++ F+P L Y I G+P R V+NRW L P T VTLT+TI
Sbjct 61 QSGRDTFVETIVAFEPSRVLGYEIAGVPKGFR-VSNRWNLEPR--AHGATTVTLTTTIRT 117
Query 122 GGNPLARLAELVVGRAMAKRSNTMLAGLAQRLE 154
L L E R MA+RS+++L LA+ E
Sbjct 118 SRALLRPLGERAFARLMARRSDSLLDSLAKATE 150
>gi|145222960|ref|YP_001133638.1| hypothetical protein Mflv_2373 [Mycobacterium gilvum PYR-GCK]
gi|315443422|ref|YP_004076301.1| polyketide cyclase / dehydrase and lipid transport [Mycobacterium
sp. Spyr1]
gi|145215446|gb|ABP44850.1| hypothetical protein Mflv_2373 [Mycobacterium gilvum PYR-GCK]
gi|315261725|gb|ADT98466.1| Polyketide cyclase / dehydrase and lipid transport [Mycobacterium
sp. Spyr1]
Length=146
Score = 97.8 bits (242), Expect = 5e-19, Method: Compositional matrix adjust.
Identities = 59/145 (41%), Positives = 76/145 (53%), Gaps = 5/145 (3%)
Query 12 RSRTIAARQQTIWDVLADFGSLSSWVEGVDHSCVLNHGPDGGALGSTRRVQVGRNTLVER 71
SR +A IW VLADFG L +W + VDH C+LN G +G +RRVQ GR+T VE
Sbjct 6 HSRQVAGDPIAIWTVLADFGGLHAWADRVDHCCLLNSREPG--IGLSRRVQSGRDTFVES 63
Query 72 VIEFDPPTTLAYRIEGLPARLRKVTNRWTLRPADPVGAVTVVTLTSTIEIGGNPLARLAE 131
+ FDPP LAY I G+P+ +NRW + T VTLTS + L AE
Sbjct 64 ITAFDPPRLLAYDISGVPSEF-TASNRWDI--GVHRDGHTAVTLTSAATVTARCLPTGAE 120
Query 132 LVVGRAMAKRSNTMLAGLAQRLEDK 156
V +A RS +L L + L +
Sbjct 121 RVFAHLVAHRSKYLLDALDRTLREN 145
>gi|213649223|ref|ZP_03379276.1| hypothetical protein SentesTy_19238 [Salmonella enterica subsp.
enterica serovar Typhi str. J185]
Length=33
Score = 65.9 bits (159), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 32/33 (97%), Positives = 33/33 (100%), Gaps = 0/33 (0%)
Query 126 LARLAELVVGRAMAKRSNTMLAGLAQRLEDKHG 158
+ARLAELVVGRAMAKRSNTMLAGLAQRLEDKHG
Sbjct 1 MARLAELVVGRAMAKRSNTMLAGLAQRLEDKHG 33
>gi|333992691|ref|YP_004525305.1| hypothetical protein JDM601_4051 [Mycobacterium sp. JDM601]
gi|333488659|gb|AEF38051.1| conserved hypothetical protein [Mycobacterium sp. JDM601]
Length=137
Score = 53.9 bits (128), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 27/72 (38%), Positives = 42/72 (59%), Gaps = 3/72 (4%)
Query 23 IWDVLADFGSLSSWVEGVDHSCVLNHGPDGGALGSTRRVQV--GRNTLVERVIEFDPPTT 80
+W+VL+D+ +SSW G+ + V P+ +G+ RR+Q G LVE + FDP
Sbjct 16 VWEVLSDYEGMSSWAPGLKITVVRPGAPEPNGVGAQRRIQAVPGMAPLVEEITVFDPDHR 75
Query 81 LAYR-IEGLPAR 91
L+YR + G+P R
Sbjct 76 LSYRGVSGIPFR 87
>gi|254438318|ref|ZP_05051812.1| hypothetical protein OA307_3188 [Octadecabacter antarcticus 307]
gi|198253764|gb|EDY78078.1| hypothetical protein OA307_3188 [Octadecabacter antarcticus 307]
Length=145
Score = 47.4 bits (111), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 34/95 (36%), Positives = 49/95 (52%), Gaps = 10/95 (10%)
Query 13 SRTIAARQQTIWDVLA-DFGSLSSWVEGVDHSCVLNHGPDGG-ALGSTRRVQVGRNTLV- 69
S I A T W V DF +S W++ + S + DG A+G TR ++ ++
Sbjct 6 SIEINASVDTAWQVFGEDFEGISKWLDAIISSSL-----DGDLAVGVTRTCNFPKDLVIK 60
Query 70 ERVIEFDPPT-TLAYRI-EGLPARLRKVTNRWTLR 102
E++ FDP T +L Y I GLPA + KV N WT+
Sbjct 61 EKLTHFDPKTRSLTYAILSGLPAFMLKVDNAWTIE 95
>gi|217976669|ref|YP_002360816.1| MxaD protein [Methylocella silvestris BL2]
gi|217502045|gb|ACK49454.1| MxaD protein, putative [Methylocella silvestris BL2]
Length=176
Score = 46.6 bits (109), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 42/151 (28%), Positives = 69/151 (46%), Gaps = 18/151 (11%)
Query 16 IAARQQTIWDVLADFGSLSSWVEGVDHSCVL-NHGPDGGALGSTRRVQVGR-NTLVERVI 73
IAA +W ++ADFG++SSW H + + DG G+TR++ + + L E +
Sbjct 33 IAASPNAVWAIVADFGAISSW-----HPLIAESQSTDGNKAGATRKLTLKKGGVLTEDLD 87
Query 74 EFDPP-TTLAYRIE-----GLPARLRKVTNRWTLRPADPVGAVTVVTLTSTI--EIGGNP 125
E+D P + +YR+E L T +++PA G TV + G P
Sbjct 88 EYDAPGMSYSYRVEDPNLDALAVSFYSAT--LSVKPA-ADGGSTVEWFGRFYRGDTGNFP 144
Query 126 LARLAELVVGRAMAKRSNTMLAGLAQRLEDK 156
L + ++M++ LAGL + E K
Sbjct 145 PEDLNDEAAQKSMSEFMKAGLAGLKAKAEAK 175
>gi|254440310|ref|ZP_05053804.1| hypothetical protein OA307_5180 [Octadecabacter antarcticus 307]
gi|198255756|gb|EDY80070.1| hypothetical protein OA307_5180 [Octadecabacter antarcticus 307]
Length=166
Score = 44.7 bits (104), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 29/66 (44%), Positives = 38/66 (58%), Gaps = 3/66 (4%)
Query 13 SRTIAARQQTIWDVLADFGSLSSWVEGVDHSCVLNHGPDGGALGSTRRVQVGRNTLVERV 72
SRTI A +WD+LADFG + ++ VD S + N G D G LG+ R ++ T V V
Sbjct 7 SRTIQAPADRVWDILADFGGVHNFHPMVDTSPITN-GQDTG-LGAERCCELYNGTKVNEV 64
Query 73 I-EFDP 77
I FDP
Sbjct 65 ITSFDP 70
>gi|220914883|ref|YP_002490191.1| MxaD protein, putative [Methylobacterium nodulans ORS 2060]
gi|219952634|gb|ACL63024.1| MxaD protein, putative [Methylobacterium nodulans ORS 2060]
Length=177
Score = 43.1 bits (100), Expect = 0.014, Method: Compositional matrix adjust.
Identities = 45/147 (31%), Positives = 61/147 (42%), Gaps = 9/147 (6%)
Query 13 SRTIAARQQTIWDVLADFGSLSSWVEGVDHSCVLNHGPDGGALGSTRRVQVGR-NTLVER 71
S IAA Q +W VL DFG + W V V + G G A G+TR V + R L E
Sbjct 32 STAIAAPPQKVWAVLGDFGGIGGWHPAV----VTSEGSGGTANGATRAVTLKRGGVLRES 87
Query 72 VIEFDPP-TTLAYRIEGLPARLRKVTNRWTLRPADPVGAVTVVTLTSTI---EIGGNPLA 127
+ E+D T +YR+ V++ P GA + V + G P
Sbjct 88 LDEYDAGRMTYSYRLSEPDLAALPVSSYSATIAVTPDGAGSRVAWFGRFYRGDTGNEPPE 147
Query 128 RLAELVVGRAMAKRSNTMLAGLAQRLE 154
L + AM T LAGL ++E
Sbjct 148 ELNDAAGRAAMKAYFETGLAGLKAKVE 174
>gi|119510311|ref|ZP_01629447.1| cyclase/dehydrase-like protein [Nodularia spumigena CCY9414]
gi|119465055|gb|EAW45956.1| cyclase/dehydrase-like protein [Nodularia spumigena CCY9414]
Length=196
Score = 42.7 bits (99), Expect = 0.018, Method: Compositional matrix adjust.
Identities = 40/155 (26%), Positives = 68/155 (44%), Gaps = 18/155 (11%)
Query 11 RRSRTIAARQQT------IWDVLADFGSLSSWVEGVDHSCVLNHGPDGG----ALGSTRR 60
R R I+A+ Q IW VL D+ +LS ++ + SC+L H P GG +GS R
Sbjct 45 ERQRKISAKIQIPQPVERIWKVLTDYEALSEFIPNLAKSCLLEH-PQGGIRLEQIGSQRL 103
Query 61 VQVGRNTLVERVIEFDPPTTLAYR-IEGLPARLRKVTNRWTLRPADPVGAVTVVTLTSTI 119
++ + V +E P + + +EG + + W L P G T+ TI
Sbjct 104 LKFNFSARVVLDLEECFPQEINFSMVEG---DFKGFSGSWCLEPYSQ-GEDQGTTVCYTI 159
Query 120 EIGGNPLARLAELVVGRAMAKRSNTMLAGLAQRLE 154
++ P + ++ R ++ L + QR+E
Sbjct 160 QVW--PKLTMPITIIERRLSNDLRVNLLAIHQRVE 192
>gi|342859685|ref|ZP_08716338.1| hypothetical protein MCOL_12418 [Mycobacterium colombiense CECT
3035]
gi|342132817|gb|EGT86037.1| hypothetical protein MCOL_12418 [Mycobacterium colombiense CECT
3035]
Length=144
Score = 42.7 bits (99), Expect = 0.019, Method: Compositional matrix adjust.
Identities = 37/113 (33%), Positives = 56/113 (50%), Gaps = 5/113 (4%)
Query 13 SRTIAARQQTIWDVLADFGSLSSWVEGVDHSCVLNHG-PDGGALGSTRRVQVGRNTLVER 71
+RT A +T++D + D ++ +V S + G P +G+ RR+ V VE
Sbjct 7 TRTSTAPIETVFDAMTDHRGIADYVWACRRSTLDREGTPAPNGVGAIRRLVVIGPPFVEE 66
Query 72 VIEFDPPTTLAYR-IEGLPARLRKVTNRWTLRPADPVGAVTVVTLTSTIEIGG 123
VIE++ PT AY+ + G P R T + LR AD G L ST++I G
Sbjct 67 VIEYERPTRYAYKMLSGAPTRNHIGTIQ--LREAD-TGTEVSWHLRSTLKIAG 116
>gi|312140175|ref|YP_004007511.1| hypothetical protein REQ_28120 [Rhodococcus equi 103S]
gi|325676943|ref|ZP_08156615.1| cyclase/dehydrase [Rhodococcus equi ATCC 33707]
gi|311889514|emb|CBH48831.1| conserved hypothetical protein [Rhodococcus equi 103S]
gi|325552243|gb|EGD21933.1| cyclase/dehydrase [Rhodococcus equi ATCC 33707]
Length=145
Score = 42.4 bits (98), Expect = 0.026, Method: Compositional matrix adjust.
Identities = 22/45 (49%), Positives = 26/45 (58%), Gaps = 0/45 (0%)
Query 10 TRRSRTIAARQQTIWDVLADFGSLSSWVEGVDHSCVLNHGPDGGA 54
T+RS TI A + V+ADFG+ SWVE VL GPDG A
Sbjct 5 TKRSITIDAPAAEVMGVIADFGAYPSWVEAAKSVEVLASGPDGRA 49
>gi|340776242|ref|ZP_08696185.1| polyketide cyclase/dehydrase [Acetobacter aceti NBRC 14818]
Length=150
Score = 41.6 bits (96), Expect = 0.042, Method: Compositional matrix adjust.
Identities = 18/52 (35%), Positives = 32/52 (62%), Gaps = 1/52 (1%)
Query 13 SRTIAARQQTIWDVLADFGSLSSWVEGVDHSCVLNHGPDGGALGSTRRVQVG 64
S + A ++WD++ DFG+L W+ GV +CV+ G +G+ RR+++G
Sbjct 7 SSVLPASVSSVWDLVRDFGALGKWLPGV-KTCVIEGDEAGDQVGAIRRLEMG 57
>gi|302869153|ref|YP_003837790.1| polyketide cyclase/dehydrase [Micromonospora aurantiaca ATCC
27029]
gi|315504371|ref|YP_004083258.1| polyketide cyclase/dehydrase [Micromonospora sp. L5]
gi|302572012|gb|ADL48214.1| Polyketide cyclase/dehydrase [Micromonospora aurantiaca ATCC
27029]
gi|315410990|gb|ADU09107.1| Polyketide cyclase/dehydrase [Micromonospora sp. L5]
Length=148
Score = 41.2 bits (95), Expect = 0.047, Method: Compositional matrix adjust.
Identities = 36/107 (34%), Positives = 48/107 (45%), Gaps = 7/107 (6%)
Query 12 RSRTIAARQQTIWDVLADFGSLSSWVEGVDHSCVLNHGPDGGALGSTRRVQVGRNTLVE- 70
RS +AA +WDV+ L +W+ GV + VL+ G G + VQ GR E
Sbjct 6 RSAHVAAPVDVVWDVVQRAEQLPAWLAGVRAAEVLS----GEGFGRRQLVQAGRGAAHEA 61
Query 71 RVIEFDPPTTLAY--RIEGLPARLRKVTNRWTLRPADPVGAVTVVTL 115
VI F PT + + R +G AR T + D G TVV L
Sbjct 62 EVIAFQEPTLIGWRERAKGAGARAEARTEIYVQLTPDEEGGGTVVRL 108
>gi|158335414|ref|YP_001516586.1| hypothetical protein AM1_2259 [Acaryochloris marina MBIC11017]
gi|158305655|gb|ABW27272.1| hypothetical protein AM1_2259 [Acaryochloris marina MBIC11017]
Length=155
Score = 41.2 bits (95), Expect = 0.049, Method: Compositional matrix adjust.
Identities = 27/90 (30%), Positives = 47/90 (53%), Gaps = 5/90 (5%)
Query 14 RTIAARQQTIWDVLADFGSLSSWVEGVDHSCVLNHGPDGGALGSTRRVQV--GRNTLVER 71
RTI A + +W+ DFG++ + + HS +L G G+ R+ + G+N + E
Sbjct 8 RTIYASLEKVWESWDDFGNIYQFNPNLTHSHLLEDSLPKGQ-GAKRQCDLNDGKNWIREE 66
Query 72 VIEFDPPTTLAYRI-EG-LPARLRKVTNRW 99
V+E+ P + + I EG +P + K T R+
Sbjct 67 VVEYIPYQQMTFNIYEGTMPLKSAKATLRF 96
>gi|148553952|ref|YP_001261534.1| hypothetical protein Swit_1029 [Sphingomonas wittichii RW1]
gi|148499142|gb|ABQ67396.1| hypothetical protein Swit_1029 [Sphingomonas wittichii RW1]
Length=145
Score = 41.2 bits (95), Expect = 0.049, Method: Compositional matrix adjust.
Identities = 21/57 (37%), Positives = 30/57 (53%), Gaps = 5/57 (8%)
Query 21 QTIWDVLADFGSLSSWVEGVDHSCVLNHGPDGGALGSTRRVQVGRNTLVERVIEFDP 77
+ +W ++ADFG LS+W GV + GP G+ RRV +G ER+ DP
Sbjct 20 ERVWPLIADFGGLSAWAAGVTGCTLEGEGP-----GAVRRVALGDRVAHERLEAIDP 71
>gi|170690404|ref|ZP_02881571.1| hypothetical protein BgramDRAFT_0380 [Burkholderia graminis C4D1M]
gi|170144839|gb|EDT13000.1| hypothetical protein BgramDRAFT_0380 [Burkholderia graminis C4D1M]
Length=164
Score = 40.8 bits (94), Expect = 0.064, Method: Compositional matrix adjust.
Identities = 23/68 (34%), Positives = 36/68 (53%), Gaps = 1/68 (1%)
Query 16 IAARQQTIWDVLADFGSLSSWVEGVDHSCVLNHGPDGGALGSTRRVQVGRNTLVERVIEF 75
++A +TIW +L DF S ++ GV H L+ G D LG+T + + V EF
Sbjct 26 VSASVETIWSLLTDFDSWPAFYPGVQHVQPLDGG-DHFGLGTTFETNLAGQDVFASVQEF 84
Query 76 DPPTTLAY 83
+P T +A+
Sbjct 85 EPMTRIAW 92
>gi|17228347|ref|NP_484895.1| hypothetical protein all0852 [Nostoc sp. PCC 7120]
gi|17130197|dbj|BAB72809.1| all0852 [Nostoc sp. PCC 7120]
Length=202
Score = 40.4 bits (93), Expect = 0.091, Method: Compositional matrix adjust.
Identities = 41/158 (26%), Positives = 70/158 (45%), Gaps = 26/158 (16%)
Query 12 RSRTIAARQQ------TIWDVLADFGSLSSWVEGVDHSCVLNHGPDGGALGSTRRVQVGR 65
R R I AR Q +W VL ++ +L+ ++ + S +L H P+GG R QVG
Sbjct 49 RQRQITARVQIPQPVEQVWQVLTNYEALADFIPNLAKSSLLEH-PNGG----IRLEQVGS 103
Query 66 NTLVE-----RVI----EFDPPTTLAYRIEGLPARLRKVTNRWTLRPADPVGAVTVVTLT 116
L+ RV+ E+ P +EG + + W L+P +G V L
Sbjct 104 QRLLNFKFCARVVLDLEEYFPKEINFQMVEG---DFKGFSGNWCLQPY-ALGNVIGTDLC 159
Query 117 STIEIGGNPLARLAELVVGRAMAKRSNTMLAGLAQRLE 154
TI++ P + ++ R +++ + L + QR+E
Sbjct 160 YTIQVW--PKLTMPITIIERRLSQDLRSNLLAIYQRVE 195
>gi|75910653|ref|YP_324949.1| cyclase/dehydrase [Anabaena variabilis ATCC 29413]
gi|75704378|gb|ABA24054.1| cyclase/dehydrase [Anabaena variabilis ATCC 29413]
Length=202
Score = 40.4 bits (93), Expect = 0.094, Method: Compositional matrix adjust.
Identities = 41/158 (26%), Positives = 70/158 (45%), Gaps = 26/158 (16%)
Query 12 RSRTIAARQQ------TIWDVLADFGSLSSWVEGVDHSCVLNHGPDGGALGSTRRVQVGR 65
R R I AR Q +W VL ++ +L+ ++ + S +L H P+GG R QVG
Sbjct 49 RQRQITARVQIPQPVEQVWQVLTNYEALADFIPNLAKSSLLEH-PNGG----IRLEQVGS 103
Query 66 NTLVE-----RVI----EFDPPTTLAYRIEGLPARLRKVTNRWTLRPADPVGAVTVVTLT 116
L+ RV+ E+ P +EG + + W L+P +G V L
Sbjct 104 QRLLNFKFCARVVLDLEEYFPKEINFQMVEG---DFKGFSGNWCLQPY-ALGDVIGTDLC 159
Query 117 STIEIGGNPLARLAELVVGRAMAKRSNTMLAGLAQRLE 154
TI++ P + ++ R +++ + L + QR+E
Sbjct 160 YTIQVW--PKLTMPITIIERRLSQDLRSNLLAIYQRVE 195
>gi|288916002|ref|ZP_06410384.1| hypothetical protein FrEUN1fDRAFT_0077 [Frankia sp. EUN1f]
gi|288352631|gb|EFC86826.1| hypothetical protein FrEUN1fDRAFT_0077 [Frankia sp. EUN1f]
Length=157
Score = 40.0 bits (92), Expect = 0.12, Method: Compositional matrix adjust.
Identities = 23/70 (33%), Positives = 36/70 (52%), Gaps = 4/70 (5%)
Query 23 IWDVLADFGSLSSWVEGVDHSCVLNHGPDGGALGSTRRVQVG--RNTLVERVIEFDPPT- 79
+W VL DF + W+E V H+ G +GS R++ VG R+T ER++ +D
Sbjct 17 VWTVLGDFHRVDRWIEIV-HASEPEDGDQAATIGSIRKLTVGDDRHTTRERLVSYDAMNR 75
Query 80 TLAYRIEGLP 89
+ Y + LP
Sbjct 76 QMTYELPDLP 85
>gi|338708509|ref|YP_004662710.1| polyketide cyclase/dehydrase [Zymomonas mobilis subsp. pomaceae
ATCC 29192]
gi|336295313|gb|AEI38420.1| Polyketide cyclase/dehydrase [Zymomonas mobilis subsp. pomaceae
ATCC 29192]
Length=149
Score = 39.7 bits (91), Expect = 0.13, Method: Compositional matrix adjust.
Identities = 18/52 (35%), Positives = 31/52 (60%), Gaps = 1/52 (1%)
Query 13 SRTIAARQQTIWDVLADFGSLSSWVEGVDHSCVLNHGPDGGALGSTRRVQVG 64
S I A ++W ++ DFG+L+ W+ GV H C + G +G+ RR+++G
Sbjct 7 SSVIHAPVSSVWRMIRDFGALADWLPGVKH-CSIEGDESGDRVGAIRRLEMG 57
>gi|254775258|ref|ZP_05216774.1| hypothetical protein MaviaA2_11391 [Mycobacterium avium subsp.
avium ATCC 25291]
Length=155
Score = 39.7 bits (91), Expect = 0.15, Method: Compositional matrix adjust.
Identities = 35/122 (29%), Positives = 56/122 (46%), Gaps = 5/122 (4%)
Query 13 SRTIAARQQTIWDVLADFGSLSSWVEG-VDHSCVLNHG-PDGGALGSTRRVQVGRNTLVE 70
+RT +A T++ ++AD + S W + V HS G P G +G+ R+V + + E
Sbjct 11 TRTSSAPAATLFRLVADGANWSRWAKPIVLHSSWAGQGDPAPGGVGAIRKVGLWPVLVQE 70
Query 71 RVIEFDPPTTLAYRIEGLPARLRKVTNRWTLRPADPVGAVTVVTLTSTIE--IGGNPLAR 128
E++P AY++ G P+ + T P +P G + S E G PL R
Sbjct 71 ETTEYEPDRRHAYKLVGPPSPAKDYTGEVVFTP-NPAGGTDIRWTGSFTEGVRGTGPLMR 129
Query 129 LA 130
A
Sbjct 130 AA 131
>gi|145595888|ref|YP_001160185.1| cyclase/dehydrase [Salinispora tropica CNB-440]
gi|145305225|gb|ABP55807.1| cyclase/dehydrase [Salinispora tropica CNB-440]
Length=148
Score = 39.7 bits (91), Expect = 0.16, Method: Compositional matrix adjust.
Identities = 34/107 (32%), Positives = 48/107 (45%), Gaps = 7/107 (6%)
Query 12 RSRTIAARQQTIWDVLADFGSLSSWVEGVDHSCVLNHGPDGGALGSTRRVQVGRNTLVE- 70
RS + A + +W V+ L +W+ GV + VL+ G G +RVQ GR E
Sbjct 6 RSSHVTAPIEAVWGVVQRAEQLPAWLAGVRAAEVLS----GEGFGRRQRVQAGRGAAHEA 61
Query 71 RVIEFDPPTTLAY--RIEGLPARLRKVTNRWTLRPADPVGAVTVVTL 115
VI + PT + + R +G AR T + AD TVV L
Sbjct 62 EVIAYQEPTLIGWRERAKGAGARAEARTEIYVQLTADEAEGGTVVRL 108
>gi|296167249|ref|ZP_06849654.1| conserved hypothetical protein [Mycobacterium parascrofulaceum
ATCC BAA-614]
gi|295897425|gb|EFG77026.1| conserved hypothetical protein [Mycobacterium parascrofulaceum
ATCC BAA-614]
Length=144
Score = 39.7 bits (91), Expect = 0.17, Method: Compositional matrix adjust.
Identities = 23/81 (29%), Positives = 41/81 (51%), Gaps = 2/81 (2%)
Query 13 SRTIAARQQTIWDVLADFGSLSSWVEGVDHSCVLNHG-PDGGALGSTRRVQVGRNTLVER 71
+RT A +T++D + D ++ + + S + G P +G+ RR+ VE
Sbjct 7 TRTSTAPIETVFDAMTDHRGIADYTWAIRRSTLDREGTPAPNGVGAIRRLAAVGPPFVEE 66
Query 72 VIEFDPPTTLAYR-IEGLPAR 91
+IE++ PT AY+ + G P R
Sbjct 67 IIEYERPTRYAYKMLSGAPTR 87
>gi|119474947|ref|ZP_01615300.1| hypothetical protein GP2143_14046 [marine gamma proteobacterium
HTCC2143]
gi|119451150|gb|EAW32383.1| hypothetical protein GP2143_14046 [marine gamma proteobacterium
HTCC2143]
Length=168
Score = 39.7 bits (91), Expect = 0.17, Method: Compositional matrix adjust.
Identities = 21/69 (31%), Positives = 34/69 (50%), Gaps = 7/69 (10%)
Query 16 IAARQQTIWDVLADFGSLSSWVEGVDHSCVLNHGPDGGALGSTRRVQVGRNTLVERVIEF 75
I + Q +W++L DFG L + + DG +G+ R + +G +VER+ EF
Sbjct 39 IGSNAQAVWNILGDFGGLKA------GGHITEFSLDGEGVGAVRTITMGGTNIVERLEEF 92
Query 76 DPPT-TLAY 83
D +L Y
Sbjct 93 DAENRSLKY 101
>gi|297195733|ref|ZP_06913131.1| conserved hypothetical protein [Streptomyces pristinaespiralis
ATCC 25486]
gi|197718923|gb|EDY62831.1| conserved hypothetical protein [Streptomyces pristinaespiralis
ATCC 25486]
Length=163
Score = 39.7 bits (91), Expect = 0.17, Method: Compositional matrix adjust.
Identities = 41/142 (29%), Positives = 66/142 (47%), Gaps = 11/142 (7%)
Query 14 RTIAARQQTIWDVLADFGSLSSWVEGVDHSCVLNHGPDGGALGSTRRVQVGR-NTLVERV 72
R AA ++W V+ADF +L+ G+ S + G +G+ R+V + +LVE V
Sbjct 23 RRAAASPASVWAVVADFPNLAGIWNGLKGSRAIGDQARG--VGARRQVDLKPVGSLVETV 80
Query 73 IEFDPPTTLAYRIEGLPARL---RKVTNRWTLRPADPVGAVTVVTLTSTIEIGGNPLARL 129
++ LA E P+ L ++ R TL DP GA T +T G P+ +L
Sbjct 81 TAWEEGRALA--TENRPSALVPMKRAAARITL---DPEGAGTAITFDYRYVPRGGPMGQL 135
Query 130 AELVVGRAMAKRSNTMLAGLAQ 151
V+ R + + MLA + +
Sbjct 136 TGPVIDRMLTGQFEGMLAAVEE 157
>gi|41407744|ref|NP_960580.1| hypothetical protein MAP1646c [Mycobacterium avium subsp. paratuberculosis
K-10]
gi|41396097|gb|AAS03963.1| hypothetical protein MAP_1646c [Mycobacterium avium subsp. paratuberculosis
K-10]
gi|336457404|gb|EGO36413.1| Polyketide cyclase / dehydrase and lipid transport [Mycobacterium
avium subsp. paratuberculosis S397]
Length=155
Score = 39.3 bits (90), Expect = 0.18, Method: Compositional matrix adjust.
Identities = 35/122 (29%), Positives = 56/122 (46%), Gaps = 5/122 (4%)
Query 13 SRTIAARQQTIWDVLADFGSLSSWVEG-VDHSCVLNHG-PDGGALGSTRRVQVGRNTLVE 70
+RT +A T++ ++AD + S W + V HS G P G +G+ R+V + + E
Sbjct 11 TRTSSAPAATLFRLVADGANWSRWAKPIVLHSSWARQGDPAPGGVGAIRKVGLWPVLVQE 70
Query 71 RVIEFDPPTTLAYRIEGLPARLRKVTNRWTLRPADPVGAVTVVTLTSTIE--IGGNPLAR 128
E++P AY++ G P+ + T P +P G + S E G PL R
Sbjct 71 ETTEYEPDRRHAYKLVGPPSPAKDYTGEVVFTP-NPAGGTDIRWTGSFTEGVRGTGPLMR 129
Query 129 LA 130
A
Sbjct 130 AA 131
>gi|118466784|ref|YP_881966.1| hypothetical protein MAV_2778 [Mycobacterium avium 104]
gi|118168071|gb|ABK68968.1| conserved hypothetical protein [Mycobacterium avium 104]
Length=155
Score = 39.3 bits (90), Expect = 0.19, Method: Compositional matrix adjust.
Identities = 35/122 (29%), Positives = 56/122 (46%), Gaps = 5/122 (4%)
Query 13 SRTIAARQQTIWDVLADFGSLSSWVEG-VDHSCVLNHG-PDGGALGSTRRVQVGRNTLVE 70
+RT +A T++ ++AD + S W + V HS G P G +G+ R+V + + E
Sbjct 11 TRTSSAPAATLFRLVADGANWSRWAKPIVLHSSWARQGDPAPGGVGAIRKVGLWPVLVQE 70
Query 71 RVIEFDPPTTLAYRIEGLPARLRKVTNRWTLRPADPVGAVTVVTLTSTIE--IGGNPLAR 128
E++P AY++ G P+ + T P +P G + S E G PL R
Sbjct 71 ETTEYEPDRRHAYKLVGPPSPAKDYTGEVVFTP-NPAGGTDIRWTGSFTEGVRGTGPLMR 129
Query 129 LA 130
A
Sbjct 130 AA 131
>gi|330469479|ref|YP_004407222.1| polyketide cyclase/dehydrase [Verrucosispora maris AB-18-032]
gi|328812450|gb|AEB46622.1| polyketide cyclase/dehydrase [Verrucosispora maris AB-18-032]
Length=148
Score = 38.9 bits (89), Expect = 0.24, Method: Compositional matrix adjust.
Identities = 25/74 (34%), Positives = 37/74 (50%), Gaps = 5/74 (6%)
Query 12 RSRTIAARQQTIWDVLADFGSLSSWVEGVDHSCVLNHGPDGGALGSTRRVQVGRNTLVE- 70
RS +AA + +WDV+ L +W+ GV + VL+ G G + VQ GR E
Sbjct 6 RSAHVAAPVEAVWDVVQRAEQLPAWLAGVRAAEVLS----GEGFGRRQLVQAGRGAAHEA 61
Query 71 RVIEFDPPTTLAYR 84
VI + PT + +R
Sbjct 62 EVIAYQEPTLIGWR 75
>gi|169627930|ref|YP_001701579.1| hypothetical protein MAB_0831 [Mycobacterium abscessus ATCC 19977]
gi|169239897|emb|CAM60925.1| Conserved hypothetical protein [Mycobacterium abscessus]
Length=145
Score = 38.9 bits (89), Expect = 0.26, Method: Compositional matrix adjust.
Identities = 42/146 (29%), Positives = 63/146 (44%), Gaps = 9/146 (6%)
Query 8 SDTRRSRTIAARQQTIWDVLADFGSLSSWVEGVDHSCVLNHGPDGGALGSTRRVQVGRNT 67
SDTR I A + I DV+ADF L W S VL G DG T +V+ T
Sbjct 4 SDTREI-VIEATPEQIMDVIADFEVLPKWSSAHQSSTVLTTGEDGRPHQVTMKVKTAGIT 62
Query 68 LVERVIEFDPPTTLAYRIEGLPARLRKVTNRWTLRPADPVGAVTVVTLTSTIEIGGNPLA 127
+ V P T+++ + ++ R+ ++T P G T V T+ +PL
Sbjct 63 DEQTVAYTWGPDTVSWTLVKA-SQQRRQDGKYTFTPQ---GDKTHVKFELTV----DPLI 114
Query 128 RLAELVVGRAMAKRSNTMLAGLAQRL 153
L V+ RA+ T GL +++
Sbjct 115 PLPGFVLKRAIKGAMETATDGLRKQV 140
>gi|296115474|ref|ZP_06834107.1| hypothetical protein GXY_06810 [Gluconacetobacter hansenii ATCC
23769]
gi|295977957|gb|EFG84702.1| hypothetical protein GXY_06810 [Gluconacetobacter hansenii ATCC
23769]
Length=144
Score = 38.5 bits (88), Expect = 0.29, Method: Compositional matrix adjust.
Identities = 17/52 (33%), Positives = 31/52 (60%), Gaps = 1/52 (1%)
Query 13 SRTIAARQQTIWDVLADFGSLSSWVEGVDHSCVLNHGPDGGALGSTRRVQVG 64
S + A ++W ++ DFG+L W+ GV +CV+ G +G+ RR+++G
Sbjct 7 SSVLPASVSSVWGLIRDFGALGKWLPGV-KTCVIEGDEPGDRVGAVRRLEMG 57
>gi|271965449|ref|YP_003339645.1| hypothetical protein Sros_3994 [Streptosporangium roseum DSM
43021]
gi|270508624|gb|ACZ86902.1| conserved hypothetical protein [Streptosporangium roseum DSM
43021]
Length=140
Score = 38.5 bits (88), Expect = 0.30, Method: Compositional matrix adjust.
Identities = 32/122 (27%), Positives = 57/122 (47%), Gaps = 6/122 (4%)
Query 13 SRTIAARQQTIWDVLADFGSLSSWVEGVDHSCVLNHGPDGGALGSTRRVQVGRNTLVERV 72
S + A + +W L DFG+L+ W+ G+ C + G D G+ RR++ T ER+
Sbjct 6 STVVNASAEEVWGYLRDFGNLAEWLPGITL-CEIEEG-DALRPGAVRRIEGPGGTFRERL 63
Query 73 IEFDPPTTLA-YRIEGLPARLRKVTNRWTLRPADPVGAVTVVTLTSTIEIGGNPLARLAE 131
+ D + A Y I P +R + + P G + ++T E + A++A+
Sbjct 64 LTVDDGSRSATYEIFESPLPVRDYRGLYRVSPVTDSGQA-FIEWSATFE--ADDAAKMAK 120
Query 132 LV 133
+V
Sbjct 121 IV 122
>gi|91786479|ref|YP_547431.1| carbon monoxide dehydrogenase subunit G [Polaromonas sp. JS666]
gi|91695704|gb|ABE42533.1| carbon monoxide dehydrogenase subunit G [Polaromonas sp. JS666]
Length=197
Score = 38.5 bits (88), Expect = 0.35, Method: Compositional matrix adjust.
Identities = 37/153 (25%), Positives = 64/153 (42%), Gaps = 10/153 (6%)
Query 9 DTRRSRTIAARQQTIWDVLADFGSLSSWVEGVDHSCVLNHGPDGGALGSTRRVQVGRNTL 68
D + SR +A QQ WD L D L + + G D V G + A+G ++
Sbjct 2 DMQGSRQLAVTQQQAWDALNDPAVLKTCIPGCDK--VEAAGENQYAIGMALKIGPVSAKF 59
Query 69 VERVIEFD--PPTT--LAYRIEGLPARLRKVTNRWTLRPADPVGAVTVVTLTSTIEIGGN 124
++ D PP + L++ +G PA K + TL P D G T+ +T+ G
Sbjct 60 SGKITLSDITPPASYRLSFEGQGGPAGFGKGSAAVTLTP-DADGCELSYTVNATV---GG 115
Query 125 PLARLAELVVGRAMAKRSNTMLAGLAQRLEDKH 157
+A+L + ++ A + ++ +H
Sbjct 116 KIAQLGQRLIDGAAKSMAEDFFKRFDGEMQRQH 148
>gi|159039150|ref|YP_001538403.1| cyclase/dehydrase [Salinispora arenicola CNS-205]
gi|157917985|gb|ABV99412.1| cyclase/dehydrase [Salinispora arenicola CNS-205]
Length=148
Score = 38.1 bits (87), Expect = 0.42, Method: Compositional matrix adjust.
Identities = 34/107 (32%), Positives = 48/107 (45%), Gaps = 7/107 (6%)
Query 12 RSRTIAARQQTIWDVLADFGSLSSWVEGVDHSCVLNHGPDGGALGSTRRVQVGRNTLVE- 70
RS + A + +W V+ L +W+ GV + VL+ G G + VQ GR T E
Sbjct 6 RSSHVTAPIEAVWGVVQRAEQLPAWLAGVRAAEVLS----GEGFGRRQLVQAGRGTAHEA 61
Query 71 RVIEFDPPTTLAY--RIEGLPARLRKVTNRWTLRPADPVGAVTVVTL 115
VI + PT + + R +G AR T + AD TVV L
Sbjct 62 EVIAYQEPTLIGWRERAKGAGARAEARTEIYVQLTADEAEGGTVVRL 108
>gi|334132818|ref|ZP_08506574.1| MxaD protein [Methyloversatilis universalis FAM5]
gi|333442302|gb|EGK70273.1| MxaD protein [Methyloversatilis universalis FAM5]
Length=175
Score = 38.1 bits (87), Expect = 0.46, Method: Compositional matrix adjust.
Identities = 32/104 (31%), Positives = 48/104 (47%), Gaps = 13/104 (12%)
Query 15 TIAARQQTIWDVLADFGSLSSWVEGVDHSCVLNHGPDGGALGSTRRVQV-GRNTLVERVI 73
TI A +W ++DF L SW V+ S N G GS R +++ G LVE +
Sbjct 35 TIKASPDAVWAKVSDFTQLQSWHPAVESSTATN----GSNAGSVRTLKLKGGGELVETLE 90
Query 74 EFDPPT-TLAYRIE---GLPARLRKVTNRWTLRPADPVGAVTVV 113
DP +YR + LP + ++ T++P D G +VV
Sbjct 91 SIDPAAKKFSYRAKDGGALP--VTNYSSNLTVKPGD--GGTSVV 130
>gi|311105019|ref|YP_003977872.1| polyketide cyclase/dehydrase family protein [Achromobacter xylosoxidans
A8]
gi|310759708|gb|ADP15157.1| polyketide cyclase/dehydrase family protein [Achromobacter xylosoxidans
A8]
Length=146
Score = 37.7 bits (86), Expect = 0.56, Method: Compositional matrix adjust.
Identities = 41/146 (29%), Positives = 62/146 (43%), Gaps = 9/146 (6%)
Query 13 SRTIAARQQTIWDVLADFGSLSSWVEGVDHSCVLNHGPDGGALGSTRRVQVGRNTLV-ER 71
S + A + +W DF L+ W GV S + G A+GS R + + V E+
Sbjct 8 SAIVHAPLEKVWACFRDFDGLARWQPGVAESRI-EEGGRHDAVGSVRYLTGKSSGFVREK 66
Query 72 VIEFDPP-TTLAYRIEGLPARLRKVTNRWTLRPADPVGAVTVVTLTSTIEIGGNPLARLA 130
++ D P TTL Y + LR +L P G T+V + + G PL+ +A
Sbjct 67 LLMLDDPGTTLRYAVIETSLPLRDGIAGVSLHPITESGH-TLVQWWADFRVEGAPLSDVA 125
Query 131 ELVVGRAMAKRSNTMLAGLAQRLEDK 156
AM T LA L +L ++
Sbjct 126 -----NAMQAMYATALAALDAKLREE 146
>gi|311695709|gb|ADP98582.1| conserved hypothetical protein [Marinobacter adhaerens HP15]
Length=144
Score = 37.7 bits (86), Expect = 0.57, Method: Compositional matrix adjust.
Identities = 34/135 (26%), Positives = 62/135 (46%), Gaps = 14/135 (10%)
Query 21 QTIWDVLADFGSLSSWVEGVDHSCVLNHGP-DGGALGSTRRVQVGRNTLVERVIEFDPPT 79
++++ ++D S + GV S ++ G + G+ R + GR L ER+ F+ P
Sbjct 15 ESVFKAISDHARYSRF-PGVSKSLLIEEGRGEKNGTGALRIIGAGRLELTERITRFERPN 73
Query 80 TLAYRIE-GLPARLRKVTNRWTLRPADPVGAVTVVTLTS----TIEIGGNPLARLAELVV 134
+ Y+IE P ++ L+P G T VT S + + G + RLAE
Sbjct 74 RMHYQIEKSSPFAVQHTKGEIVLKPE---GEQTRVTWVSEGHVQVPLLGGVMDRLAE--- 127
Query 135 GRAMAKRSNTMLAGL 149
R+ ++ N++L +
Sbjct 128 -RSFSRAFNSLLKSI 141
>gi|134099544|ref|YP_001105205.1| cyclase/dehydrase [Saccharopolyspora erythraea NRRL 2338]
gi|291009272|ref|ZP_06567245.1| cyclase/dehydrase [Saccharopolyspora erythraea NRRL 2338]
gi|133912167|emb|CAM02280.1| cyclase/dehydrase [Saccharopolyspora erythraea NRRL 2338]
Length=172
Score = 37.7 bits (86), Expect = 0.57, Method: Compositional matrix adjust.
Identities = 19/49 (39%), Positives = 28/49 (58%), Gaps = 1/49 (2%)
Query 55 LGSTRRVQVGRNTLVERVIEFDPPTTLAYRIEGLPARLRKVTNRWTLRP 103
+GS+R +G + RV+EFDPP A+ +EG P T R+T+ P
Sbjct 63 VGSSRHESLGEWSTSSRVVEFDPPRVFAWEVEG-PDADPSATWRFTVEP 110
>gi|345013238|ref|YP_004815592.1| polyketide cyclase/dehydrase [Streptomyces violaceusniger Tu
4113]
gi|344039587|gb|AEM85312.1| Polyketide cyclase/dehydrase [Streptomyces violaceusniger Tu
4113]
Length=157
Score = 37.4 bits (85), Expect = 0.81, Method: Compositional matrix adjust.
Identities = 30/96 (32%), Positives = 41/96 (43%), Gaps = 7/96 (7%)
Query 16 IAARQQTIWDVLADFGSLSSWVEGVDHSCVLNHGPDGGALGSTRRVQVGRNTLVERVIEF 75
I+A + +++ D W V + DGG + R V GR E V+
Sbjct 26 ISASPEAVFEAFTDVEGWPRWFTSVKEA----RSTDGGKGRAIRLVGGGR--FRETVMAV 79
Query 76 DPPTTLAYRIEGLPAR-LRKVTNRWTLRPADPVGAV 110
DP AYR++ A LR + WTLRP D G V
Sbjct 80 DPHERYAYRVDETNAPGLRALLEEWTLRPTDGGGTV 115
Lambda K H
0.319 0.135 0.397
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 128907826664
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
Posted date: Sep 5, 2011 4:36 AM
Number of letters in database: 5,219,829,388
Number of sequences in database: 15,229,318
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40