BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv3093c Length=334 Score E Sequences producing significant alignments: (Bits) Value gi|15610230|ref|NP_217609.1| oxidoreductase [Mycobacterium tuber... 650 0.0 gi|31794272|ref|NP_856765.1| oxidoreductase [Mycobacterium bovis... 646 0.0 gi|167969699|ref|ZP_02551976.1| hypothetical oxidoreductase [Myc... 646 0.0 gi|340628084|ref|YP_004746536.1| hypothetical protein MCAN_31191... 643 0.0 gi|289448772|ref|ZP_06438516.1| oxidoreductase [Mycobacterium tu... 585 3e-165 gi|240168662|ref|ZP_04747321.1| oxidoreductase [Mycobacterium ka... 471 7e-131 gi|289763271|ref|ZP_06522649.1| conserved hypothetical protein [... 449 3e-124 gi|183981573|ref|YP_001849864.1| oxidoreductase [Mycobacterium m... 444 9e-123 gi|298526565|ref|ZP_07013974.1| conserved hypothetical protein [... 384 1e-104 gi|345012286|ref|YP_004814640.1| putative F420-dependent oxidore... 321 1e-85 gi|331699053|ref|YP_004335292.1| putative F420-dependent oxidore... 249 5e-64 gi|271963073|ref|YP_003337269.1| coenzyme F420-dependent N5 N10-... 243 3e-62 gi|254482216|ref|ZP_05095457.1| Luciferase-like monooxygenase su... 239 5e-61 gi|254365720|ref|ZP_04981765.1| hypothetical oxidoreductase [Myc... 238 1e-60 gi|300788784|ref|YP_003769075.1| oxidoreductase [Amycolatopsis m... 219 4e-55 gi|226307967|ref|YP_002767927.1| hypothetical protein RER_44800 ... 200 2e-49 gi|297161046|gb|ADI10758.1| Coenzyme F420-dependent N5 N10-methy... 194 2e-47 gi|229495130|ref|ZP_04388876.1| conserved hypothetical oxidoredu... 184 1e-44 gi|302550447|ref|ZP_07302789.1| oxidoreductase [Streptomyces vir... 177 2e-42 gi|256391381|ref|YP_003112945.1| oxidoreductase [Catenulispora a... 123 4e-26 gi|256379127|ref|YP_003102787.1| luciferase-like monooxygenase [... 110 4e-22 gi|134099545|ref|YP_001105206.1| FMN-dependent monooxygenase [Sa... 109 7e-22 gi|300789466|ref|YP_003769757.1| FMN-dependent monooxygenase [Am... 106 5e-21 gi|345004879|ref|YP_004807732.1| 5,10-methylenetetrahydromethano... 104 2e-20 gi|269128174|ref|YP_003301544.1| luciferase-like monooxygenase [... 104 2e-20 gi|296271475|ref|YP_003654107.1| luciferase-like monooxygenase [... 103 4e-20 gi|271970470|ref|YP_003344666.1| coenzyme F420-dependent N5 N10-... 102 7e-20 gi|16554492|ref|NP_444216.1| flavin-dependent oxidoreductase [Ha... 102 1e-19 gi|300710887|ref|YP_003736701.1| N5N10-methylenetetrahydromethan... 100 2e-19 gi|284166171|ref|YP_003404450.1| 5,10-methylenetetrahydromethano... 100 3e-19 gi|183980369|ref|YP_001848660.1| coenzyme F420-dependent oxidore... 100 4e-19 gi|118619837|ref|YP_908169.1| coenzyme F420-dependent oxidoreduc... 99.8 6e-19 gi|317124875|ref|YP_004098987.1| F420-dependent oxidoreductase [... 99.4 7e-19 gi|284034897|ref|YP_003384828.1| luciferase-like monooxygenase [... 99.4 8e-19 gi|76802821|ref|YP_330916.1| alkanesulfonate monooxygenase [Natr... 99.4 8e-19 gi|289580736|ref|YP_003479202.1| 5,10-methylenetetrahydromethano... 98.6 1e-18 gi|298243661|ref|ZP_06967468.1| 5,10-methylenetetrahydromethanop... 98.6 1e-18 gi|300786515|ref|YP_003766806.1| coenzyme F420-dependent N5,N10-... 98.2 2e-18 gi|330468968|ref|YP_004406711.1| luciferase-like, subgroup [Verr... 98.2 2e-18 gi|300784594|ref|YP_003764885.1| luciferase family protein [Amyc... 97.1 4e-18 gi|315428016|dbj|BAJ49605.1| FMN-dependent monooxygenase [Candid... 96.3 6e-18 gi|315426661|dbj|BAJ48287.1| FMN-dependent monooxygenase [Candid... 95.9 7e-18 gi|302529664|ref|ZP_07282006.1| 5,10-methylenetetrahydromethanop... 95.9 7e-18 gi|322369288|ref|ZP_08043853.1| N5N10-methylenetetrahydromethano... 94.7 2e-17 gi|158314537|ref|YP_001507045.1| luciferase family protein [Fran... 94.7 2e-17 gi|302561524|ref|ZP_07313866.1| 5,10-methylenetetrahydromethanop... 93.6 4e-17 gi|4218561|emb|CAA09650.1| putative FMN-dependent monooxygenase ... 93.6 4e-17 gi|119475720|ref|ZP_01616073.1| hypothetical protein GP2143_1791... 92.8 7e-17 gi|290954923|ref|YP_003486105.1| oxidoreductase [Streptomyces sc... 92.8 7e-17 gi|312197446|ref|YP_004017507.1| F420-dependent oxidoreductase [... 92.8 7e-17 >gi|15610230|ref|NP_217609.1| oxidoreductase [Mycobacterium tuberculosis H37Rv] gi|148662947|ref|YP_001284470.1| oxidoreductase [Mycobacterium tuberculosis H37Ra] gi|306777402|ref|ZP_07415739.1| oxidoreductase [Mycobacterium tuberculosis SUMu001] 7 more sequence titles Length=334 Score = 650 bits (1678), Expect = 0.0, Method: Compositional matrix adjust. Identities = 334/334 (100%), Positives = 334/334 (100%), Gaps = 0/334 (0%) Query 1 MTDIEVALPFWLDRPDHEATDVALAAADTGFAALWIGEMATYDAFALATSIGLRTPNMTL 60 MTDIEVALPFWLDRPDHEATDVALAAADTGFAALWIGEMATYDAFALATSIGLRTPNMTL Sbjct 1 MTDIEVALPFWLDRPDHEATDVALAAADTGFAALWIGEMATYDAFALATSIGLRTPNMTL 60 Query 61 KVGPLAVGVRGPVGLALGVSSVASLTGCRVDLALGASSPAIVAGWHGRPWAHHVPVMRET 120 KVGPLAVGVRGPVGLALGVSSVASLTGCRVDLALGASSPAIVAGWHGRPWAHHVPVMRET Sbjct 61 KVGPLAVGVRGPVGLALGVSSVASLTGCRVDLALGASSPAIVAGWHGRPWAHHVPVMRET 120 Query 121 IECLRSIFTGARVEYSGRHVNSRGFRLRGAAPDTRIALGAFGPGMIRLAAQHADEVVLNL 180 IECLRSIFTGARVEYSGRHVNSRGFRLRGAAPDTRIALGAFGPGMIRLAAQHADEVVLNL Sbjct 121 IECLRSIFTGARVEYSGRHVNSRGFRLRGAAPDTRIALGAFGPGMIRLAAQHADEVVLNL 180 Query 181 ASPFRVGRVRAAIDSAAAAAGRAAPRLTVCVPVAVNPGAAAHSQLAAQLAVYLAPPGYGE 240 ASPFRVGRVRAAIDSAAAAAGRAAPRLTVCVPVAVNPGAAAHSQLAAQLAVYLAPPGYGE Sbjct 181 ASPFRVGRVRAAIDSAAAAAGRAAPRLTVCVPVAVNPGAAAHSQLAAQLAVYLAPPGYGE 240 Query 241 MFSALGFDGLVRSARSRATRRELAVAVPSELLDRVCALGSPDRVAARLRAYADAGADCVA 300 MFSALGFDGLVRSARSRATRRELAVAVPSELLDRVCALGSPDRVAARLRAYADAGADCVA Sbjct 241 MFSALGFDGLVRSARSRATRRELAVAVPSELLDRVCALGSPDRVAARLRAYADAGADCVA 300 Query 301 VVPATAEDPGGRVALRALRPGGLYGTAGDNDGRR 334 VVPATAEDPGGRVALRALRPGGLYGTAGDNDGRR Sbjct 301 VVPATAEDPGGRVALRALRPGGLYGTAGDNDGRR 334 >gi|31794272|ref|NP_856765.1| oxidoreductase [Mycobacterium bovis AF2122/97] gi|121638978|ref|YP_979202.1| putative oxidoreductase [Mycobacterium bovis BCG str. Pasteur 1173P2] gi|148824285|ref|YP_001289039.1| oxidoreductase [Mycobacterium tuberculosis F11] 51 more sequence titles Length=334 Score = 646 bits (1666), Expect = 0.0, Method: Compositional matrix adjust. Identities = 333/334 (99%), Positives = 333/334 (99%), Gaps = 0/334 (0%) Query 1 MTDIEVALPFWLDRPDHEATDVALAAADTGFAALWIGEMATYDAFALATSIGLRTPNMTL 60 MTDIEVALPFWLDRPDHEATDVALAAADTGFAALWIGEMATYDAFALATSIGLRTPNMTL Sbjct 1 MTDIEVALPFWLDRPDHEATDVALAAADTGFAALWIGEMATYDAFALATSIGLRTPNMTL 60 Query 61 KVGPLAVGVRGPVGLALGVSSVASLTGCRVDLALGASSPAIVAGWHGRPWAHHVPVMRET 120 KVGPLAVGVRGPVGLALGVSSVASLTGCRVDLALGASSPAIVAGWHGRPWAHHVPVMRET Sbjct 61 KVGPLAVGVRGPVGLALGVSSVASLTGCRVDLALGASSPAIVAGWHGRPWAHHVPVMRET 120 Query 121 IECLRSIFTGARVEYSGRHVNSRGFRLRGAAPDTRIALGAFGPGMIRLAAQHADEVVLNL 180 IECLRSIFTGARVEYSGRHVNSRGFRLRGAAPDTRIALGAFGPGMIRLAAQHADEVVLNL Sbjct 121 IECLRSIFTGARVEYSGRHVNSRGFRLRGAAPDTRIALGAFGPGMIRLAAQHADEVVLNL 180 Query 181 ASPFRVGRVRAAIDSAAAAAGRAAPRLTVCVPVAVNPGAAAHSQLAAQLAVYLAPPGYGE 240 ASPFRVGRVRAAIDSAAAAAGRAAPRLTV VPVAVNPGAAAHSQLAAQLAVYLAPPGYGE Sbjct 181 ASPFRVGRVRAAIDSAAAAAGRAAPRLTVWVPVAVNPGAAAHSQLAAQLAVYLAPPGYGE 240 Query 241 MFSALGFDGLVRSARSRATRRELAVAVPSELLDRVCALGSPDRVAARLRAYADAGADCVA 300 MFSALGFDGLVRSARSRATRRELAVAVPSELLDRVCALGSPDRVAARLRAYADAGADCVA Sbjct 241 MFSALGFDGLVRSARSRATRRELAVAVPSELLDRVCALGSPDRVAARLRAYADAGADCVA 300 Query 301 VVPATAEDPGGRVALRALRPGGLYGTAGDNDGRR 334 VVPATAEDPGGRVALRALRPGGLYGTAGDNDGRR Sbjct 301 VVPATAEDPGGRVALRALRPGGLYGTAGDNDGRR 334 >gi|167969699|ref|ZP_02551976.1| hypothetical oxidoreductase [Mycobacterium tuberculosis H37Ra] Length=334 Score = 646 bits (1666), Expect = 0.0, Method: Compositional matrix adjust. Identities = 332/334 (99%), Positives = 332/334 (99%), Gaps = 0/334 (0%) Query 1 MTDIEVALPFWLDRPDHEATDVALAAADTGFAALWIGEMATYDAFALATSIGLRTPNMTL 60 MTDIEVALPFWLDRPDHEATDVALAAADTGFAALWIGEMATYDAFALATSIGLRTPNMTL Sbjct 1 MTDIEVALPFWLDRPDHEATDVALAAADTGFAALWIGEMATYDAFALATSIGLRTPNMTL 60 Query 61 KVGPLAVGVRGPVGLALGVSSVASLTGCRVDLALGASSPAIVAGWHGRPWAHHVPVMRET 120 KVGPLAVGVRGPVGLALGVSSVASLTGCRVDLALGASSPAIVAGWHGRPWAHHVPVMRET Sbjct 61 KVGPLAVGVRGPVGLALGVSSVASLTGCRVDLALGASSPAIVAGWHGRPWAHHVPVMRET 120 Query 121 IECLRSIFTGARVEYSGRHVNSRGFRLRGAAPDTRIALGAFGPGMIRLAAQHADEVVLNL 180 IECLRSIFTGARVEYSGRHVNSRGFRLRGAAPDTRIALGAFGPGMIRLAAQHADEVVLNL Sbjct 121 IECLRSIFTGARVEYSGRHVNSRGFRLRGAAPDTRIALGAFGPGMIRLAAQHADEVVLNL 180 Query 181 ASPFRVGRVRAAIDSAAAAAGRAAPRLTVCVPVAVNPGAAAHSQLAAQLAVYLAPPGYGE 240 ASPFRVGRVRAAIDSAAAAAGRAAPRLTVCVPVAVNPGAAAHSQLAAQLAVYLAPPGYGE Sbjct 181 ASPFRVGRVRAAIDSAAAAAGRAAPRLTVCVPVAVNPGAAAHSQLAAQLAVYLAPPGYGE 240 Query 241 MFSALGFDGLVRSARSRATRRELAVAVPSELLDRVCALGSPDRVAARLRAYADAGADCVA 300 MFSALGFDGLVRSARSRATRR LAVAVPS LLDRVCALGSPDRVAARLRAYADAGADCVA Sbjct 241 MFSALGFDGLVRSARSRATRRALAVAVPSALLDRVCALGSPDRVAARLRAYADAGADCVA 300 Query 301 VVPATAEDPGGRVALRALRPGGLYGTAGDNDGRR 334 VVPATAEDPGGRVALRALRPGGLYGTAGDNDGRR Sbjct 301 VVPATAEDPGGRVALRALRPGGLYGTAGDNDGRR 334 >gi|340628084|ref|YP_004746536.1| hypothetical protein MCAN_31191 [Mycobacterium canettii CIPT 140010059] gi|340006274|emb|CCC45450.1| hypothetical oxidoreductase [Mycobacterium canettii CIPT 140010059] Length=334 Score = 643 bits (1659), Expect = 0.0, Method: Compositional matrix adjust. Identities = 332/334 (99%), Positives = 332/334 (99%), Gaps = 0/334 (0%) Query 1 MTDIEVALPFWLDRPDHEATDVALAAADTGFAALWIGEMATYDAFALATSIGLRTPNMTL 60 MTDIEVALPFWLDRPDHEATDVALAAADTGFAALWIGEMATYDAFALATSIGLRTPNMTL Sbjct 1 MTDIEVALPFWLDRPDHEATDVALAAADTGFAALWIGEMATYDAFALATSIGLRTPNMTL 60 Query 61 KVGPLAVGVRGPVGLALGVSSVASLTGCRVDLALGASSPAIVAGWHGRPWAHHVPVMRET 120 KVGPLAVGVRGPVGLALGVSSVASLTGCRVDLALGASSPAIVAGWHGRPWAHHVPVMRET Sbjct 61 KVGPLAVGVRGPVGLALGVSSVASLTGCRVDLALGASSPAIVAGWHGRPWAHHVPVMRET 120 Query 121 IECLRSIFTGARVEYSGRHVNSRGFRLRGAAPDTRIALGAFGPGMIRLAAQHADEVVLNL 180 IECLRSIFTGARVEYSGRHVNSRGFRLRGAAPDTRIALGAFGPGMIRLAAQHADEVVLNL Sbjct 121 IECLRSIFTGARVEYSGRHVNSRGFRLRGAAPDTRIALGAFGPGMIRLAAQHADEVVLNL 180 Query 181 ASPFRVGRVRAAIDSAAAAAGRAAPRLTVCVPVAVNPGAAAHSQLAAQLAVYLAPPGYGE 240 ASPFRVGRVRAAIDSAAAAAGRAAPRLTV VPVAVNPGAAAHSQLAAQLAVYLAPPGYGE Sbjct 181 ASPFRVGRVRAAIDSAAAAAGRAAPRLTVWVPVAVNPGAAAHSQLAAQLAVYLAPPGYGE 240 Query 241 MFSALGFDGLVRSARSRATRRELAVAVPSELLDRVCALGSPDRVAARLRAYADAGADCVA 300 MFSALGFDGLVRSARSRATRRELAVAVP ELLDRVCALGSPDRVAARLRAYADAGADCVA Sbjct 241 MFSALGFDGLVRSARSRATRRELAVAVPGELLDRVCALGSPDRVAARLRAYADAGADCVA 300 Query 301 VVPATAEDPGGRVALRALRPGGLYGTAGDNDGRR 334 VVPATAEDPGGRVALRALRPGGLYGTAGDNDGRR Sbjct 301 VVPATAEDPGGRVALRALRPGGLYGTAGDNDGRR 334 >gi|289448772|ref|ZP_06438516.1| oxidoreductase [Mycobacterium tuberculosis CPHL_A] gi|289421730|gb|EFD18931.1| oxidoreductase [Mycobacterium tuberculosis CPHL_A] Length=314 Score = 585 bits (1508), Expect = 3e-165, Method: Compositional matrix adjust. Identities = 303/304 (99%), Positives = 303/304 (99%), Gaps = 0/304 (0%) Query 31 FAALWIGEMATYDAFALATSIGLRTPNMTLKVGPLAVGVRGPVGLALGVSSVASLTGCRV 90 FAALWIGEMATYDAFALATSIGLRTPNMTLKVGPLAVGVRGPVGLALGVSSVASLTGCRV Sbjct 11 FAALWIGEMATYDAFALATSIGLRTPNMTLKVGPLAVGVRGPVGLALGVSSVASLTGCRV 70 Query 91 DLALGASSPAIVAGWHGRPWAHHVPVMRETIECLRSIFTGARVEYSGRHVNSRGFRLRGA 150 DLALGASSPAIVAGWHGRPWAHHVPVMRETIECLRSIFTGARVEYSGRHVNSRGFRLRGA Sbjct 71 DLALGASSPAIVAGWHGRPWAHHVPVMRETIECLRSIFTGARVEYSGRHVNSRGFRLRGA 130 Query 151 APDTRIALGAFGPGMIRLAAQHADEVVLNLASPFRVGRVRAAIDSAAAAAGRAAPRLTVC 210 APDTRIALGAFGPGMIRLAAQHADEVVLNLASPFRVGRVRAAIDSAAAAAGRAAPRLTV Sbjct 131 APDTRIALGAFGPGMIRLAAQHADEVVLNLASPFRVGRVRAAIDSAAAAAGRAAPRLTVW 190 Query 211 VPVAVNPGAAAHSQLAAQLAVYLAPPGYGEMFSALGFDGLVRSARSRATRRELAVAVPSE 270 VPVAVNPGAAAHSQLAAQLAVYLAPPGYGEMFSALGFDGLVRSARSRATRRELAVAVPSE Sbjct 191 VPVAVNPGAAAHSQLAAQLAVYLAPPGYGEMFSALGFDGLVRSARSRATRRELAVAVPSE 250 Query 271 LLDRVCALGSPDRVAARLRAYADAGADCVAVVPATAEDPGGRVALRALRPGGLYGTAGDN 330 LLDRVCALGSPDRVAARLRAYADAGADCVAVVPATAEDPGGRVALRALRPGGLYGTAGDN Sbjct 251 LLDRVCALGSPDRVAARLRAYADAGADCVAVVPATAEDPGGRVALRALRPGGLYGTAGDN 310 Query 331 DGRR 334 DGRR Sbjct 311 DGRR 314 >gi|240168662|ref|ZP_04747321.1| oxidoreductase [Mycobacterium kansasii ATCC 12478] Length=332 Score = 471 bits (1212), Expect = 7e-131, Method: Compositional matrix adjust. Identities = 251/317 (80%), Positives = 278/317 (88%), Gaps = 0/317 (0%) Query 3 DIEVALPFWLDRPDHEATDVALAAADTGFAALWIGEMATYDAFALATSIGLRTPNMTLKV 62 D+EV LPFWLDRPDHEA +VALAA+D GF LWIGEMATYDAFALAT++G+R P++TLK+ Sbjct 5 DVEVVLPFWLDRPDHEAIEVALAASDAGFDGLWIGEMATYDAFALATAVGMRAPHLTLKI 64 Query 63 GPLAVGVRGPVGLALGVSSVASLTGCRVDLALGASSPAIVAGWHGRPWAHHVPVMRETIE 122 GPLAVGVRGPV LALGV+SVA+LTG RVDLALGASSPAIV+GWH R WAHHVPVMRETIE Sbjct 65 GPLAVGVRGPVTLALGVASVAALTGNRVDLALGASSPAIVSGWHNRQWAHHVPVMRETIE 124 Query 123 CLRSIFTGARVEYSGRHVNSRGFRLRGAAPDTRIALGAFGPGMIRLAAQHADEVVLNLAS 182 CLR I G RV+Y+GRHV+S GFRLR A PDTRIALGAFGPGMIRLAA+HADEVVLNLAS Sbjct 125 CLRPILAGERVDYAGRHVSSHGFRLRDAPPDTRIALGAFGPGMIRLAARHADEVVLNLAS 184 Query 183 PFRVGRVRAAIDSAAAAAGRAAPRLTVCVPVAVNPGAAAHSQLAAQLAVYLAPPGYGEMF 242 P RV +VR +D+ AAA R APRLT VPVAVNPGAAAH+Q+AAQLAVYLAPPGYGEMF Sbjct 185 PARVAQVREVLDTEAAAVRRPAPRLTAWVPVAVNPGAAAHAQVAAQLAVYLAPPGYGEMF 244 Query 243 SALGFDGLVRSARSRATRRELAVAVPSELLDRVCALGSPDRVAARLRAYADAGADCVAVV 302 +ALGF LVRSAR+ ATRRELA AVP ELLD+V ALG D VAARLRAY DAGADCVAVV Sbjct 245 AALGFGDLVRSARTGATRRELAAAVPVELLDQVGALGGADEVAARLRAYHDAGADCVAVV 304 Query 303 PATAEDPGGRVALRALR 319 P+TAEDPGGR+ LR +R Sbjct 305 PSTAEDPGGRMTLRTVR 321 >gi|289763271|ref|ZP_06522649.1| conserved hypothetical protein [Mycobacterium tuberculosis GM 1503] gi|289710777|gb|EFD74793.1| conserved hypothetical protein [Mycobacterium tuberculosis GM 1503] Length=233 Score = 449 bits (1154), Expect = 3e-124, Method: Compositional matrix adjust. Identities = 231/233 (99%), Positives = 232/233 (99%), Gaps = 0/233 (0%) Query 102 VAGWHGRPWAHHVPVMRETIECLRSIFTGARVEYSGRHVNSRGFRLRGAAPDTRIALGAF 161 +AGWHGRPWAHHVPVMRETIECLRSIFTGARVEYSGRHVNSRGFRLRGAAPDTRIALGAF Sbjct 1 MAGWHGRPWAHHVPVMRETIECLRSIFTGARVEYSGRHVNSRGFRLRGAAPDTRIALGAF 60 Query 162 GPGMIRLAAQHADEVVLNLASPFRVGRVRAAIDSAAAAAGRAAPRLTVCVPVAVNPGAAA 221 GPGMIRLAAQHADEVVLNLASPFRVGRVRAAIDSAAAAAGRAAPRLTV VPVAVNPGAAA Sbjct 61 GPGMIRLAAQHADEVVLNLASPFRVGRVRAAIDSAAAAAGRAAPRLTVWVPVAVNPGAAA 120 Query 222 HSQLAAQLAVYLAPPGYGEMFSALGFDGLVRSARSRATRRELAVAVPSELLDRVCALGSP 281 HSQLAAQLAVYLAPPGYGEMFSALGFDGLVRSARSRATRRELAVAVPSELLDRVCALGSP Sbjct 121 HSQLAAQLAVYLAPPGYGEMFSALGFDGLVRSARSRATRRELAVAVPSELLDRVCALGSP 180 Query 282 DRVAARLRAYADAGADCVAVVPATAEDPGGRVALRALRPGGLYGTAGDNDGRR 334 DRVAARLRAYADAGADCVAVVPATAEDPGGRVALRALRPGGLYGTAGDNDGRR Sbjct 181 DRVAARLRAYADAGADCVAVVPATAEDPGGRVALRALRPGGLYGTAGDNDGRR 233 >gi|183981573|ref|YP_001849864.1| oxidoreductase [Mycobacterium marinum M] gi|183174899|gb|ACC40009.1| conserved hypothetical oxidoreductase [Mycobacterium marinum M] Length=325 Score = 444 bits (1142), Expect = 9e-123, Method: Compositional matrix adjust. Identities = 254/323 (79%), Positives = 277/323 (86%), Gaps = 1/323 (0%) Query 1 MTDIEVALPFWLDRPDHEATDVALAAADTGFAALWIGEMATYDAFALATSIGLRTPNMTL 60 MTD+EVALPFWLDRPD EA +VALAA++ GF LW+GEMATYDAFALAT+IGL P M L Sbjct 1 MTDLEVALPFWLDRPDDEAMEVALAASNAGFDVLWVGEMATYDAFALATAIGLGAPGMGL 60 Query 61 KVGPLAVGVRGPVGLALGVSSVASLTGCRVDLALGASSPAIVAGWHGRPWAHHVPVMRET 120 K+GPLAV VRGPVGLALGVSSVASLTG RVD+ALGASSPAIVAGWH RPWAHHVPVMRET Sbjct 61 KIGPLAVAVRGPVGLALGVSSVASLTGSRVDIALGASSPAIVAGWHDRPWAHHVPVMRET 120 Query 121 IECLRSIFTGARVEYSGRHVNSRGFRLRGAAPDTRIALGAFGPGMIRLAAQHADEVVLNL 180 IECLRSI GARV+Y GRHV S GFRLR P+ RIALGAFGPGMIRLAA+HADEVVLNL Sbjct 121 IECLRSILGGARVDYHGRHVASHGFRLRNPQPEARIALGAFGPGMIRLAARHADEVVLNL 180 Query 181 ASPFRVGRVRAAIDS-AAAAAGRAAPRLTVCVPVAVNPGAAAHSQLAAQLAVYLAPPGYG 239 ASP RV VR AIDS AAAAAGRAAPRLTV VPVAV+PGAAAH+QLAAQLAVYL PPGYG Sbjct 181 ASPARVAEVRHAIDSAAAAAAGRAAPRLTVWVPVAVDPGAAAHAQLAAQLAVYLGPPGYG 240 Query 240 EMFSALGFDGLVRSARSRATRRELAVAVPSELLDRVCALGSPDRVAARLRAYADAGADCV 299 EMFSALGFD LV +AR+ A+RRELA A+P ELL++V ALG+ +RVAARLR Y AGADC+ Sbjct 241 EMFSALGFDRLVGAARAGASRRELAAAIPVELLEQVGALGTAERVAARLRDYEAAGADCL 300 Query 300 AVVPATAEDPGGRVALRALRPGG 322 A+VP TAEDP GR L AL G Sbjct 301 ALVPCTAEDPAGRATLNALSRKG 323 >gi|298526565|ref|ZP_07013974.1| conserved hypothetical protein [Mycobacterium tuberculosis 94_M4241A] gi|298496359|gb|EFI31653.1| conserved hypothetical protein [Mycobacterium tuberculosis 94_M4241A] Length=229 Score = 384 bits (987), Expect = 1e-104, Method: Compositional matrix adjust. Identities = 202/209 (97%), Positives = 204/209 (98%), Gaps = 0/209 (0%) Query 1 MTDIEVALPFWLDRPDHEATDVALAAADTGFAALWIGEMATYDAFALATSIGLRTPNMTL 60 MTDIEVALPFWLDRPDHEATDVALAAADTGFAALWIGEMATYDAFALATSIGLRTPNMTL Sbjct 1 MTDIEVALPFWLDRPDHEATDVALAAADTGFAALWIGEMATYDAFALATSIGLRTPNMTL 60 Query 61 KVGPLAVGVRGPVGLALGVSSVASLTGCRVDLALGASSPAIVAGWHGRPWAHHVPVMRET 120 KVGPLAVGVRGPVGLALGVSSVASLTGCRVDLALGASSPAIVAGWHGRPWAHHVPVMRET Sbjct 61 KVGPLAVGVRGPVGLALGVSSVASLTGCRVDLALGASSPAIVAGWHGRPWAHHVPVMRET 120 Query 121 IECLRSIFTGARVEYSGRHVNSRGFRLRGAAPDTRIALGAFGPGMIRLAAQHADEVVLNL 180 IECLRSIFTGARVEYSGRHVNSRGFRLRGAAPDTRIALGAFGPGMIRLAAQHADEVVLNL Sbjct 121 IECLRSIFTGARVEYSGRHVNSRGFRLRGAAPDTRIALGAFGPGMIRLAAQHADEVVLNL 180 Query 181 ASPFRVGRVRAAIDSAAAAAGRAAPRLTV 209 ASPFRVGRVRAAIDSAAAA+GR L + Sbjct 181 ASPFRVGRVRAAIDSAAAASGRVTTHLII 209 >gi|345012286|ref|YP_004814640.1| putative F420-dependent oxidoreductase [Streptomyces violaceusniger Tu 4113] gi|344038635|gb|AEM84360.1| putative F420-dependent oxidoreductase [Streptomyces violaceusniger Tu 4113] Length=351 Score = 321 bits (822), Expect = 1e-85, Method: Compositional matrix adjust. Identities = 169/314 (54%), Positives = 213/314 (68%), Gaps = 0/314 (0%) Query 6 VALPFWLDRPDHEATDVALAAADTGFAALWIGEMATYDAFALATSIGLRTPNMTLKVGPL 65 V LP+WLDRPD EA +A A++ GF LW+GEMAT+D FALAT++ T L VGPL Sbjct 8 VVLPYWLDRPDLEALGIAHQASECGFERLWLGEMATFDVFALATAVANSTSIPRLTVGPL 67 Query 66 AVGVRGPVGLALGVSSVASLTGCRVDLALGASSPAIVAGWHGRPWAHHVPVMRETIECLR 125 AVGVR PV +A+G +SVA+LTG VD+ALGASSP IV+ WH R W+ + RE++ LR Sbjct 68 AVGVRSPVAIAMGAASVATLTGTHVDVALGASSPHIVSDWHDRSWSGNPQRTRESVTVLR 127 Query 126 SIFTGARVEYSGRHVNSRGFRLRGAAPDTRIALGAFGPGMIRLAAQHADEVVLNLASPFR 185 + G R +SGRH+ +RGFRLR PD+ I++ AFGP M R+AA+ ADEVVLNL P Sbjct 128 ELLGGGRAAFSGRHIRTRGFRLRQPQPDSTISVAAFGPRMTRVAAETADEVVLNLVPPEH 187 Query 186 VGRVRAAIDSAAAAAGRAAPRLTVCVPVAVNPGAAAHSQLAAQLAVYLAPPGYGEMFSAL 245 + VRA+ID++A A G +PRL V V +V P A H QLA+QLAVYL PPGYGEMF+ L Sbjct 188 IAEVRASIDASAEARGLPSPRLAVWVTCSVEPHPATHHQLASQLAVYLRPPGYGEMFTEL 247 Query 246 GFDGLVRSARSRATRRELAVAVPSELLDRVCALGSPDRVAARLRAYADAGADCVAVVPAT 305 GF LVR ARS A R L +P EL V A+GS V R+ +Y +AGAD + +VP T Sbjct 248 GFGSLVRQARSTAGRHTLVPEIPPELPAAVGAIGSGPEVLRRIESYFNAGADHIGLVPTT 307 Query 306 AEDPGGRVALRALR 319 A+DP G L +R Sbjct 308 ADDPDGAKTLGFIR 321 >gi|331699053|ref|YP_004335292.1| putative F420-dependent oxidoreductase [Pseudonocardia dioxanivorans CB1190] gi|326953742|gb|AEA27439.1| putative F420-dependent oxidoreductase [Pseudonocardia dioxanivorans CB1190] Length=320 Score = 249 bits (635), Expect = 5e-64, Method: Compositional matrix adjust. Identities = 152/321 (48%), Positives = 201/321 (63%), Gaps = 4/321 (1%) Query 1 MTDIEVALPFWLDRPDHEATDVALAAADTGFAALWIGEMATYDAFALATSIGLRTPNMTL 60 MT++ V+L W DRP EA D A AA + G+A LWIGEMATYDAFALA ++ P L Sbjct 1 MTELSVSLGLWQDRPSIEAVDTARAADELGYARLWIGEMATYDAFALAAALPGTIP---L 57 Query 61 KVGPLAVGVRGPVGLALGVSSVASLTGCRVDLALGASSPAIVAGWHGRPWAHHVPVMRET 120 +GP AV VR PV +A+G ++VA LTG V++A+G+SSP +V+ WHGR + ET Sbjct 58 VLGPFAVAVRTPVQIAVGAATVAELTGRTVEVAIGSSSPVVVSAWHGRAAPAPALALAET 117 Query 121 IECLRSIFTGARVEYSGRHVNSRGFRLRGAAPDTRIALGAFGPGMIRLAAQHADEVVLNL 180 + LR++ G R + G+ V +RG+RLR AP + + AFGP +R+A ++AD +VLNL Sbjct 118 AQTLRTLLDGGRADVDGKVVRTRGYRLRAPAPGGPVTIAAFGPQAVRVAGRYADRMVLNL 177 Query 181 ASPFRVGRVRAAIDSAAAAAGRAAPRLTVCVPVAVNPGAAAHSQLAAQLAVYLAPPGYGE 240 P R+ A+ +AA AGR PR+ V AV+P A A ++LA + YLA PGYGE Sbjct 178 LPPSVATRLVEAVRAAAREAGREPPRVAAWVTAAVDPDAEAMARLARGVVGYLAVPGYGE 237 Query 241 MFSALGFDGLVRSARSRATRRELAVAVPSELLDRVCALGSPDRVAARLRAYADAGADCVA 300 +F+ GF LV AR+ + REL AVPS L V A+G+ D V AR+ YA AG D V Sbjct 238 VFAEAGFGDLVGFARTGPSPRELFAAVPSSLTAAVGAIGTVDEVTARIAEYAAAGVDEVC 297 Query 301 VVP-ATAEDPGGRVALRALRP 320 +VP AT DP GR L AL P Sbjct 298 LVPVATDADPAGRRTLTALAP 318 >gi|271963073|ref|YP_003337269.1| coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase-like protein [Streptosporangium roseum DSM 43021] gi|270506248|gb|ACZ84526.1| Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase-like protein [Streptosporangium roseum DSM 43021] Length=323 Score = 243 bits (620), Expect = 3e-62, Method: Compositional matrix adjust. Identities = 148/314 (48%), Positives = 195/314 (63%), Gaps = 5/314 (1%) Query 6 VALPFWLDRPDHEATDVALAAADTGFAALWIGEMATYDAFALATSIGLRTPNMTLKVGPL 65 V+L W DRP EA A AA + G+ LW+GEMATYDAFALAT++GL T + L VGPL Sbjct 12 VSLGLWQDRPAGEALLTARAADELGYGELWVGEMATYDAFALATAVGLATGRIGLTVGPL 71 Query 66 AVGVRGPVGLALGVSSVASLTGCRVDLALGASSPAIVAGWHGRPWAHHVPVMRETIECLR 125 AV VR P+ +A+GV+SV+ L G VD+A+G SSP +V GWHGR A +RE + LR Sbjct 72 AVTVRDPMMIAMGVASVSDLVGRPVDVAVGTSSPLVVEGWHGRSRARAATALREAVRALR 131 Query 126 SIFTGARVEYSGRHVNSRGFRLRGAAPDTRIALGAFGPGMIRLAAQHADEVVLNLASPFR 185 + G R +++G ++SRG+ LR AP + +++ AFG +R AA AD +VLNL +P Sbjct 132 PLLDGGRSDFAGECLSSRGYHLRLPAPRSELSVAAFGASAVRTAAT-ADRMVLNLVTPAS 190 Query 186 VGRVRAAIDSAAAAAGRAAPRLTVCVPVAVNPGAAAHSQLAAQLAVYLAPPGYGEMFSAL 245 R+ A + +A+ PR+ V AV+PG A ++ + YLA PGYGEMF+ Sbjct 191 AARLVADLRTASEG---PPPRVAAWVTAAVDPGREAVDRIRRGVVGYLAAPGYGEMFAEA 247 Query 246 GFDGLVRSARSRATRRELAVAVPSELLDRVCALGSPDRVAARLRAYADAGADCVAVVP-A 304 GF +V AR+R REL A+P LL+ V LG V RL AYA+AG D VA+VP A Sbjct 248 GFGDVVEFARTRPHPRELLAAIPDGLLESVALLGDVGAVRERLGAYAEAGVDEVALVPVA 307 Query 305 TAEDPGGRVALRAL 318 T DPGG LRAL Sbjct 308 TDADPGGVATLRAL 321 >gi|254482216|ref|ZP_05095457.1| Luciferase-like monooxygenase superfamily protein [marine gamma proteobacterium HTCC2148] gi|214037541|gb|EEB78207.1| Luciferase-like monooxygenase superfamily protein [marine gamma proteobacterium HTCC2148] Length=325 Score = 239 bits (609), Expect = 5e-61, Method: Compositional matrix adjust. Identities = 138/314 (44%), Positives = 189/314 (61%), Gaps = 0/314 (0%) Query 6 VALPFWLDRPDHEATDVALAAADTGFAALWIGEMATYDAFALATSIGLRTPNMTLKVGPL 65 V P W DRP E VA A GF LWIGEMATYDAFA AT+ GL+T ++ L VGPL Sbjct 5 VVTPLWQDRPAAENLQVAKLADRLGFEELWIGEMATYDAFAFATAAGLQTEHIRLTVGPL 64 Query 66 AVGVRGPVGLALGVSSVASLTGCRVDLALGASSPAIVAGWHGRPWAHHVPVMRETIECLR 125 +V VR P+ +A+G +SVA +TG R +ALGASS +V WHGR + E+ + LR Sbjct 65 SVSVRTPMTIAMGAASVADITGRRTAVALGASSVVVVEEWHGRDRTRTATHLAESAQILR 124 Query 126 SIFTGARVEYSGRHVNSRGFRLRGAAPDTRIALGAFGPGMIRLAAQHADEVVLNLASPFR 185 ++ G + ++SG +S+G++LR A + I + AFGP +R AA+HAD ++LN+ +P Sbjct 125 ALLAGEKTDFSGECASSKGYKLRLDAVEGPITIAAFGPAAVRAAARHADRMLLNMVTPLS 184 Query 186 VGRVRAAIDSAAAAAGRAAPRLTVCVPVAVNPGAAAHSQLAAQLAVYLAPPGYGEMFSAL 245 V +R + AA AGRA P + + +P AVNP QL + YLA PGYGEM Sbjct 185 VAALRDQLIRAAEKAGRATPEIAIWLPCAVNPQRETIDQLKRGIVGYLAAPGYGEMMMQA 244 Query 246 GFDGLVRSARSRATRRELAVAVPSELLDRVCALGSPDRVAARLRAYADAGADCVAVVPAT 305 GF+ LV AR+R REL A+P +L+ + +G + AR+ Y DAGA + +VPAT Sbjct 245 GFEDLVNYARTRPHPRELLAAMPDKLISAIGLVGDLSAIQARVDEYRDAGAGEICLVPAT 304 Query 306 AEDPGGRVALRALR 319 A D GR L ++ Sbjct 305 AGDELGRQTLETMK 318 >gi|254365720|ref|ZP_04981765.1| hypothetical oxidoreductase [Mycobacterium tuberculosis str. Haarlem] gi|134151233|gb|EBA43278.1| hypothetical oxidoreductase [Mycobacterium tuberculosis str. Haarlem] Length=126 Score = 238 bits (607), Expect = 1e-60, Method: Compositional matrix adjust. Identities = 124/124 (100%), Positives = 124/124 (100%), Gaps = 0/124 (0%) Query 211 VPVAVNPGAAAHSQLAAQLAVYLAPPGYGEMFSALGFDGLVRSARSRATRRELAVAVPSE 270 VPVAVNPGAAAHSQLAAQLAVYLAPPGYGEMFSALGFDGLVRSARSRATRRELAVAVPSE Sbjct 3 VPVAVNPGAAAHSQLAAQLAVYLAPPGYGEMFSALGFDGLVRSARSRATRRELAVAVPSE 62 Query 271 LLDRVCALGSPDRVAARLRAYADAGADCVAVVPATAEDPGGRVALRALRPGGLYGTAGDN 330 LLDRVCALGSPDRVAARLRAYADAGADCVAVVPATAEDPGGRVALRALRPGGLYGTAGDN Sbjct 63 LLDRVCALGSPDRVAARLRAYADAGADCVAVVPATAEDPGGRVALRALRPGGLYGTAGDN 122 Query 331 DGRR 334 DGRR Sbjct 123 DGRR 126 >gi|300788784|ref|YP_003769075.1| oxidoreductase [Amycolatopsis mediterranei U32] gi|299798298|gb|ADJ48673.1| oxidoreductase [Amycolatopsis mediterranei U32] gi|340530403|gb|AEK45608.1| oxidoreductase [Amycolatopsis mediterranei S699] Length=327 Score = 219 bits (559), Expect = 4e-55, Method: Compositional matrix adjust. Identities = 141/317 (45%), Positives = 188/317 (60%), Gaps = 1/317 (0%) Query 4 IEVALPFWLDRPDHEATDVALAAADTGFAALWIGEMATYDAFALATSIGLRTPNMTLKVG 63 + +L W DRP EA D A AA G+ LWIGEMAT+DAFAL T+IG T ++L G Sbjct 3 LSASLGLWQDRPPEEALDTARAAEAAGYPELWIGEMATWDAFALGTAIGAATSRISLTFG 62 Query 64 PLAVGVRGPVGLALGVSSVASLTGCRVDLALGASSPAIVAGWHGRPWAHHVPVMRETIEC 123 PLAV VR P +A+GV+SVA+LTG +ALG SS +V GWHGR + E+ Sbjct 63 PLAVTVRDPATIAMGVASVAALTGRATGVALGTSSDVVVRGWHGRSRDRAATALAESAVA 122 Query 124 LRSIFTGARVEYSGRHVNSRGFRLRGAAPDTRIALGAFGPGMIRLAAQHADEVVLNLASP 183 +R + G + G V S G+RLR AP++ + + AFGP + +AA+HAD +V+NL SP Sbjct 123 VRQLLAGEKSSVDGTVVGSLGYRLRLPAPESPLTIAAFGPRALDVAARHADRMVVNLVSP 182 Query 184 FRVGRVRAAIDSAAAAAGRAAPRLTVCVPVAVNPGAAAHSQLAAQLAVYLAPPGYGEMFS 243 + + +AA AG P + V A +PG A QL + YLA PGY +MF Sbjct 183 AAAATLVRGLHAAAGRAGTTPPPVAAWVVAAADPGPAELEQLRRGVVGYLAAPGYADMFR 242 Query 244 ALGFDGLVRSARSRATRRELAVAVPSELLDRVCALGSPDRVAARLRAYADAGADCVAVVP 303 A GF L+ AR+R REL AVP+E + V GS D +AA++ +YA AG D +A+VP Sbjct 243 AAGFGDLIDFARTRPHPRELLAAVPAEAIAAVGLFGSRDEIAAKIGSYAAAGVDELAIVP 302 Query 304 ATA-EDPGGRVALRALR 319 AT+ +DPGG L A R Sbjct 303 ATSDDDPGGEKTLAACR 319 >gi|226307967|ref|YP_002767927.1| hypothetical protein RER_44800 [Rhodococcus erythropolis PR4] gi|226187084|dbj|BAH35188.1| conserved hypothetical protein [Rhodococcus erythropolis PR4] Length=319 Score = 200 bits (509), Expect = 2e-49, Method: Compositional matrix adjust. Identities = 124/313 (40%), Positives = 171/313 (55%), Gaps = 4/313 (1%) Query 10 FWLDRPDHEATDVALAAADTGFAALWIGEMATYDAFALATSIGLRTPNMTLKVGPLAVGV 69 W DRP E T A A GF +W+GEMATYDAFALATS+G + L VGPLAV V Sbjct 3 LWQDRPPREVTTTARLADKLGFGRVWVGEMATYDAFALATSVGAGFEHSELVVGPLAVTV 62 Query 70 RGPVGLALGVSSVASLTGCRVDLALGASSPAIVAGWHGRPWAHHVPVMRETIECLRSIFT 129 R P +A+G +SVA LTG V +ALG SS +V WHGR + + E+ +R++ Sbjct 63 RDPAMIAIGAASVADLTGRHVSIALGTSSTVVVEKWHGRSRSGAARALAESARGVRALMN 122 Query 130 GARVEYSGRHVNSRGFRLRGAAPDTRIALGAFGPGMIRLAAQHADEVVLNLASPFRVGRV 189 G R E +G + + G+RLR P R+ + AFG +R A + DE+VLNL SP + GR+ Sbjct 123 GERGEVAGTVMRTSGYRLRLQPPGGRLIVAAFGDKALRAAVELGDELVLNLVSPEQAGRL 182 Query 190 RAAIDSAAAAAGRAAPRLTVCVPVAV---NPGAAAHSQLAAQLAVYLAPPGYGEMFSALG 246 A AA P+++V P AV P + QL L YLA PGY +MF G Sbjct 183 IARCKEIAAEMETPMPQVSVWAPAAVATEGPTQMSIDQLRRGLVPYLAAPGYSDMFVRAG 242 Query 247 FDGLVRSARSRATRRELAVAVPSELLDRVCALGSPDRVAARLRAYADAGADCVAVVPATA 306 F ++ +AR+ A RE+ V ++ V +G+ +L AY G + V VP++ Sbjct 243 FASVIEAARAGAAPREILSQVSDAMVATVGIVGTAADAREQLEAYRAVGVETVVAVPSST 302 Query 307 E-DPGGRVALRAL 318 + DP G+V + L Sbjct 303 DSDPAGQVTMELL 315 >gi|297161046|gb|ADI10758.1| Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase-like protein [Streptomyces bingchenggensis BCW-1] Length=334 Score = 194 bits (493), Expect = 2e-47, Method: Compositional matrix adjust. Identities = 128/313 (41%), Positives = 171/313 (55%), Gaps = 3/313 (0%) Query 10 FWLDRPDHEATDVALAAADTGFAALWIGEMATYDAFALATSIGLRTPNMTLKVGPLAVGV 69 W DRP HEA + A A + F LWIGE TYD FALAT+IG T + L +GPL V V Sbjct 3 LWKDRPTHEALETAKLADEYNFPELWIGERETYDTFALATAIGSCTQRIPLTLGPLPVAV 62 Query 70 RGPVGLALGVSSVASLTGCR-VDLALGASSPAIVAGWHGRPWAHHVPVMRETIECLRSIF 128 R P +A G +SVA+L+G R V +A+G SSP IV GWHGR M E+++ LR Sbjct 63 RDPAMIARGAASVAALSGGRKVRIAVGPSSPIIVTGWHGRDHRRPARAMSESVQALRHFL 122 Query 129 TGARVEYSGRHVNSRGFRLRGAAPDTRIALGAFGPGMIRLAAQHADEVVLNLASPFRVGR 188 R G+ + +RG+RLR AP + + AFG IR AA+ AD + + L + Sbjct 123 AQERAVVDGQVIRTRGYRLRLPAPTGYLTMAAFGTHTIRTAARQADRMAVALVTVETAAE 182 Query 189 VRAAIDSAAAAAGRAAPRLTVCVPVAVNPGAAAHSQLAAQLAVYLAPPGYGEMFSALGFD 248 + + + AA R P + VPVA GAAA Q+ LA YL PGY EMF+ G+ Sbjct 183 LAKQLAKESEAALRPRPPVAAWVPVAATAGAAALKQVRNMLADYLNAPGYSEMFARAGYG 242 Query 249 GLVRSARS--RATRRELAVAVPSELLDRVCALGSPDRVAARLRAYADAGADCVAVVPATA 306 +V ARS R R +L AVP EL+ ++ G + V L AY A + VA+ +T Sbjct 243 DVVDFARSSPRPRRSQLIEAVPFELVKKIGIFGDKEAVRQGLLAYGAAVDEVVALPCSTP 302 Query 307 EDPGGRVALRALR 319 +DP G L+ L+ Sbjct 303 DDPSGAHTLQVLQ 315 >gi|229495130|ref|ZP_04388876.1| conserved hypothetical oxidoreductase [Rhodococcus erythropolis SK121] gi|229318061|gb|EEN83936.1| conserved hypothetical oxidoreductase [Rhodococcus erythropolis SK121] Length=308 Score = 184 bits (468), Expect = 1e-44, Method: Compositional matrix adjust. Identities = 115/293 (40%), Positives = 162/293 (56%), Gaps = 4/293 (1%) Query 30 GFAALWIGEMATYDAFALATSIGLRTPNMTLKVGPLAVGVRGPVGLALGVSSVASLTGCR 89 GF +W+GEMATYDAFALATS+G + L VGPLAV VR P +A+G +SV+ LTG Sbjct 12 GFGRVWVGEMATYDAFALATSVGTGFEHSELVVGPLAVTVRDPAMIAIGAASVSDLTGRD 71 Query 90 VDLALGASSPAIVAGWHGRPWAHHVPVMRETIECLRSIFTGARVEYSGRHVNSRGFRLRG 149 V +ALG SS +V WHGR + + E+ +R++ G R E +G + + G+RLR Sbjct 72 VSIALGTSSTVVVEKWHGRSRSGAARALAESARGVRALMNGERGEVAGTVMRTSGYRLRL 131 Query 150 AAPDTRIALGAFGPGMIRLAAQHADEVVLNLASPFRVGRVRAAIDSAAAAAGRAAPRLTV 209 P R+ + AFG +R A + DE+VLNL S + GR+ AA P+++V Sbjct 132 QPPGGRLIVAAFGDKALRAAVELGDELVLNLVSAEQAGRLITRCKEIAAETETVMPQVSV 191 Query 210 CVPVAV---NPGAAAHSQLAAQLAVYLAPPGYGEMFSALGFDGLVRSARSRATRRELAVA 266 P AV P + QL L YLA PGY +MF GF ++ +AR+ REL+ Sbjct 192 WAPAAVATEGPTQMSIDQLRRGLVPYLAAPGYSDMFVRAGFADVIEAARAGTAPRELSSQ 251 Query 267 VPSELLDRVCALGSPDRVAARLRAYADAGADCVAVVPATAE-DPGGRVALRAL 318 V ++ V +G+ A+L AY AG D V VP++ + DP G+ + L Sbjct 252 VSDAMVAAVGIVGTAADARAQLEAYRAAGVDTVVAVPSSTDSDPAGQETMELL 304 >gi|302550447|ref|ZP_07302789.1| oxidoreductase [Streptomyces viridochromogenes DSM 40736] gi|302468065|gb|EFL31158.1| oxidoreductase [Streptomyces viridochromogenes DSM 40736] Length=328 Score = 177 bits (449), Expect = 2e-42, Method: Compositional matrix adjust. Identities = 119/308 (39%), Positives = 164/308 (54%), Gaps = 3/308 (0%) Query 13 DRPDHEATDVALAAADTGFAALWIGEMATYDAFALATSIGLRTPNMTLKVGPLAVGVRGP 72 D P E VA+ A G+ +W GE AT+D+F LAT+IG T L GP+ V VR P Sbjct 23 DSPIEEPLRVAMLADRLGYREVWAGEGATWDSFVLATAIGAATEQAVLTAGPVPVNVRDP 82 Query 73 VGLALGVSSVASLTGCRVDLALGASSPAIVAGWHGRPWAHHVPVMRETIECLRSIFTGAR 132 + + G +S A++TG V +ALG SS +V G HGRP + E++ + ++ Sbjct 83 LTIVRGAASTAAVTGRPVGVALGTSSKRVVEGVHGRPRTRPAATLAESVAAVSALMHSVP 142 Query 133 VEYSGRHVNSRGFRLRGAAPDTRIALGAFGPGMIRLAAQHADEVVLNLASPFRVGRVRAA 192 E V GF R P + + AFG + A +HAD ++L++ SP +V +RA Sbjct 143 GEPI---VPGSGFLRRLPPPGGMVTVAAFGERAVAAAVEHADRMLLDIVSPEQVRMLRAR 199 Query 193 IDSAAAAAGRAAPRLTVCVPVAVNPGAAAHSQLAAQLAVYLAPPGYGEMFSALGFDGLVR 252 + +AA AGR PRL +P AV+P Q+ + YL PGY +MF GF +V Sbjct 200 MLAAAEKAGRTPPRLASWLPAAVDPKPETLQQVLRSVVGYLRVPGYSDMFVDAGFAEIVE 259 Query 253 SARSRATRRELAVAVPSELLDRVCALGSPDRVAARLRAYADAGADCVAVVPATAEDPGGR 312 A A L A+P E+ V +G D V AR+ AYA+AG D +A+VPATA DP G Sbjct 260 LAAKGADPDTLLRAMPPEVAGTVALVGDADTVRARIDAYAEAGLDEIALVPATAGDPAGE 319 Query 313 VALRALRP 320 L ALRP Sbjct 320 RTLGALRP 327 >gi|256391381|ref|YP_003112945.1| oxidoreductase [Catenulispora acidiphila DSM 44928] gi|256357607|gb|ACU71104.1| oxidoreductase [Catenulispora acidiphila DSM 44928] Length=357 Score = 123 bits (309), Expect = 4e-26, Method: Compositional matrix adjust. Identities = 87/252 (35%), Positives = 125/252 (50%), Gaps = 0/252 (0%) Query 56 PNMTLKVGPLAVGVRGPVGLALGVSSVASLTGCRVDLALGASSPAIVAGWHGRPWAHHVP 115 P L +GPL VR PV A G +SVA+LTG + LAL AS+ +V WHGRP Sbjct 93 PLAALTLGPLPAAVRDPVTAARGAASVAALTGRDIGLALTASTGLVVVDWHGRPRTDPAT 152 Query 116 VMRETIECLRSIFTGARVEYSGRHVNSRGFRLRGAAPDTRIALGAFGPGMIRLAAQHADE 175 + E++ L + G V + G V SRGFR R + + AFG +A AD Sbjct 153 ALAESLSVLAPLTRGEPVSFQGVSVRSRGFRSRLEPSHASLTVLAFGLEACEVAVGRADR 212 Query 176 VVLNLASPFRVGRVRAAIDSAAAAAGRAAPRLTVCVPVAVNPGAAAHSQLAAQLAVYLAP 235 V + LA+ R++A + + RA PRL V +P V+P A + + L YL Sbjct 213 VAVPLATVEHAARIKARLALTSDRMNRAVPRLAVFLPTVVDPDAESLDWIRRSLLPYLDA 272 Query 236 PGYGEMFSALGFDGLVRSARSRATRRELAVAVPSELLDRVCALGSPDRVAARLRAYADAG 295 G+G MF+ G L+ AR A R L A+P E+L + A+G ++V Y AG Sbjct 273 DGFGRMFAEAGHGELIDLARGGAHERSLLAAMPEEVLRSIAAVGDLNQVCTAFEDYRQAG 332 Query 296 ADCVAVVPATAE 307 D + ++P + + Sbjct 333 VDEIVMLPESYD 344 >gi|256379127|ref|YP_003102787.1| luciferase-like monooxygenase [Actinosynnema mirum DSM 43827] gi|255923430|gb|ACU38941.1| Luciferase-like monooxygenase [Actinosynnema mirum DSM 43827] Length=327 Score = 110 bits (274), Expect = 4e-22, Method: Compositional matrix adjust. Identities = 100/303 (34%), Positives = 141/303 (47%), Gaps = 22/303 (7%) Query 15 PDHEATDVALAAADTGFAALWIGEMATYDAFALATSIGLRTPNMTLKVGPLAVGVRGPVG 74 PDH A L A G+ +W E + DAF +P + L V RGP Sbjct 25 PDHRALVAELTA--LGYTDVWSAETSGSDAFTPLALAAQWSPEVRLGTAIAPVYTRGPAL 82 Query 75 LALGVSSVASLTGCRVDLALGASSPAIVAGWHGRPWAHHVPVMRETIECLRSIFTGARVE 134 LA+ +++A ++G R L +G+SSPAIV W+G +A R+T+ LR+ G +V Sbjct 83 LAMSAATLAEVSGGRFVLGIGSSSPAIVTRWNGAEFAEPYARTRDTLRFLRAALAGEKVT 142 Query 135 YSGRHVNSRGFRLRGAAPDTR--IALGAFGPGMIRLAAQHADEVVLNLASPFRVGRVRAA 192 + GFRL AP+ I L A PGM+RLAA+ AD + N + V RVR A Sbjct 143 REYPTFSVSGFRLE-KAPEHHVPIVLAALRPGMLRLAAREADGAITNWLAAEDVPRVREA 201 Query 193 I--DSAAAAAGRAAPRLTVCVPVAVNPGAAAHSQLAAQLAVYLAPPGYGEMFSALGF-DG 249 + D AA R+ VC AA + A + YL P Y LG + Sbjct 202 LGPDKELAA------RIFVC---PTEDADAARALGRALICAYLTVPAYAAFHDWLGRGEA 252 Query 250 L--VRSARSRATRRELAVAVPSELLDRVCALGSPDRVAARLRAYADAGADC--VAVVPAT 305 L +R A + R E VP E++D + GSP+R + + YA G D + ++P T Sbjct 253 LTPMREAWAAGRRTEANALVPDEVVDALVVHGSPERCRSEIAQYAANGVDTPIIGLLP-T 311 Query 306 AED 308 ED Sbjct 312 GED 314 >gi|134099545|ref|YP_001105206.1| FMN-dependent monooxygenase [Saccharopolyspora erythraea NRRL 2338] gi|291009271|ref|ZP_06567244.1| FMN-dependent monooxygenase [Saccharopolyspora erythraea NRRL 2338] gi|133912168|emb|CAM02281.1| FMN-dependent monooxygenase [Saccharopolyspora erythraea NRRL 2338] Length=353 Score = 109 bits (272), Expect = 7e-22, Method: Compositional matrix adjust. Identities = 103/325 (32%), Positives = 140/325 (44%), Gaps = 26/325 (8%) Query 14 RPDHEATDVALAAADTGFAALWIGEMATYDAFALATSIGLRTPNMTLKVGPLAVGVRGPV 73 R E ++A+ A G W+ E D + + RT M L G + +G R PV Sbjct 13 RTWSEPMELAVEAEKLGLDVCWVAEAWGSDGPSALGYLAARTDRMLLGSGIMQLGTRTPV 72 Query 74 GLALGVSSVASLTGCRVDLALGASSPAIVAGWHGRPWAHHVPVMRETIECLRSIFTGARV 133 +A +++ L+G R L LG S P +V G HG P+A + MRET+E +R G ++ Sbjct 73 AIAQAAIALSQLSGGRFLLGLGPSGPQVVEGLHGVPFARPLVRMRETVEIVRQAIAGEKI 132 Query 134 EYSGRHV------NSRGFRLRGAAP-DTRIALGAFGPGMIRLAAQHADEVVLNLASPFRV 186 YSGRH SR RL A D + L P M+RL + AD + P Sbjct 133 SYSGRHFRIPLPGESRPMRLSMRAEHDIPVYLATLSPAMLRLTGRVADGWLGTSFVPEGA 192 Query 187 GRVR-AAIDSAAAAAGRAAPRLTVCVPVAVNPGAAAHSQL-------AAQLAVYLAPPG- 237 A +DS A AGR+ L VC V AA QL +LA L G Sbjct 193 DEAYFAHLDSGLADAGRSRADLDVCQGAEV-AFAADEDQLREMVAGRKKELAFSLGGMGS 251 Query 238 -----YGEMFSALGFDGLVRSARSR---ATRRELAVAVPSELLDRVCALGSPDRVAARLR 289 Y +S G+ + R R R A V E++ +G+ D V RLR Sbjct 252 ATTNFYNNAYSRQGWVQVAAEVRERWQAGDRDGAAELVTDEMVLATTLIGTEDGVRTRLR 311 Query 290 AYADAGADCVAVVPATAEDPGGRVA 314 + DAG D V + PA ED R+A Sbjct 312 VWRDAGVDTVRLYPA-GEDLDARLA 335 >gi|300789466|ref|YP_003769757.1| FMN-dependent monooxygenase [Amycolatopsis mediterranei U32] gi|299798980|gb|ADJ49355.1| FMN-dependent monooxygenase [Amycolatopsis mediterranei U32] gi|340531120|gb|AEK46325.1| FMN-dependent monooxygenase [Amycolatopsis mediterranei S699] Length=341 Score = 106 bits (265), Expect = 5e-21, Method: Compositional matrix adjust. Identities = 93/306 (31%), Positives = 129/306 (43%), Gaps = 22/306 (7%) Query 21 DVALAAADTGFAALWIGEMATYDAFALATSIGLRTPNMTLKVGPLAVGVRGPVGLALGVS 80 D L A G W+ E DA + + RT + L G + +G R PV +A Sbjct 18 DFVLEAEKLGLDVCWVAEAWGSDAPSALGYLAARTDRIRLGSGIIQLGTRTPVAIAQAAL 77 Query 81 SVASLTGCRVDLALGASSPAIVAGWHGRPWAHHVPVMRETIECLRSIFTGARVEYSGRHV 140 ++A L+G R L LG S P +V G HG P+A + MRET+E +R F G ++ +SGR Sbjct 78 TLADLSGGRFALGLGPSGPQVVEGLHGVPFAKPLTRMRETVEIIRQAFAGEKISFSGRAF 137 Query 141 ------NSRGFRLRGA-APDTRIALGAFGPGMIRLAAQHADEVVLNLASPFRVGRVRAAI 193 +R RL A PD I L P ++ L + AD + P + Sbjct 138 EIPLPGEARPMRLSTAPNPDIPIYLATLSPKLLELTGEVADGWLGTSFVPEGADAYFTHL 197 Query 194 DSAAAAAGRAAPRLTVC--VPVAVNPGAAAHSQL----AAQLAVYLAPPG------YGEM 241 D+ A AGR + VC VA A L +LA L G Y Sbjct 198 DAGLAKAGRQRKDIDVCQGAEVAFADNEAELRTLVGSRKKELAFSLGGMGSASTNFYNNA 257 Query 242 FSALGFDGLVRSARSR---ATRRELAVAVPSELLDRVCALGSPDRVAARLRAYADAGADC 298 +S G+ + R R R A V E++ LG+ + V RLR + DAG D Sbjct 258 YSRQGWADVAAEVRERWQAGDRDGAAALVTDEMVLGTTLLGTEEMVRERLRVWRDAGIDT 317 Query 299 VAVVPA 304 V + PA Sbjct 318 VRLYPA 323 >gi|345004879|ref|YP_004807732.1| 5,10-methylenetetrahydromethanopterin reductase [halophilic archaeon DL31] gi|344320505|gb|AEN05359.1| 5,10-methylenetetrahydromethanopterin reductase [halophilic archaeon DL31] Length=334 Score = 104 bits (260), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 91/310 (30%), Positives = 140/310 (46%), Gaps = 14/310 (4%) Query 4 IEVALPFWLDRPDHEATDVALAAADTGFAALWIGEMATYDAFALATSIGLRTPNMTLKVG 63 +E++LP + +A+ A G+ +W+ E DA + + RT + L Sbjct 5 MELSLPVAAQPSLDDVVSLAVDAEAAGYERVWLPETWGRDAVTMLSLAAERTETVELGTS 64 Query 64 PLAVGVRGPVGLALGVSSVASLTGCRVDLALGASSPAIVAGWHGRPWAHHVPVMRETIEC 123 + V R P L +++ + R L +G S PA++ WHG+P+ + RET+E Sbjct 65 IVNVYSRSPALLGQTAATLQEASDGRFRLGIGPSGPAVIENWHGQPFTQPLRQTRETVEI 124 Query 124 LRSIFTGARVEYSGRHVNSRGFRLRGAAPDTRIALGA--FGPGMIRLAAQHADEVVLNLA 181 ++ + +G VEY+G H + GFRLR AP+ + A GP + LA + AD Sbjct 125 IKQVLSGEPVEYAGDHFDLSGFRLRCDAPEPAPPVDAAGMGPKAVELAGRFADGWHALTF 184 Query 182 SPFRVGRVRAAIDSAAAAAGRAAP--RLTVCVPVAVNPGAAAHSQLAAQ-LAVYLAPPGY 238 +P + A + A R R+T+ +P A LA Q LA Y+ G Sbjct 185 TPDGMCERLADLRRGAEMGDRDPENVRVTLSLPCCALEDAEQARSLARQHLAFYIG--GM 242 Query 239 GEMF-SALGFDGLVRSARS-----RATRRELAVAVPSELLDRVCALGSPDRVAARLRAYA 292 G + AL G +A +A R AVA LLD + A+GSP+ RL A+ Sbjct 243 GTFYRDALARQGHADTAEQIYDAWQAGERGTAVAAIDPLLDDLAAVGSPEHARERLAAFG 302 Query 293 DA-GADCVAV 301 D G D V+V Sbjct 303 DIDGVDAVSV 312 >gi|269128174|ref|YP_003301544.1| luciferase-like monooxygenase [Thermomonospora curvata DSM 43183] gi|268313132|gb|ACY99506.1| Luciferase-like monooxygenase [Thermomonospora curvata DSM 43183] Length=318 Score = 104 bits (259), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 98/315 (32%), Positives = 140/315 (45%), Gaps = 23/315 (7%) Query 15 PDHEATDVALAAADTGFAALWIGEMATYDAF---ALATSIGLRTPNMTLKVGPLAVGVRG 71 P E + D G+ +W E D F AL++ G P++ L + V RG Sbjct 15 PLAEHRQIVTELTDLGYTDVWSAETNGADGFTPLALSSQWG---PDLRLGTAIVPVYTRG 71 Query 72 PVGLALGVSSVASLTGCRVDLALGASSPAIVAGWHGRPWAHHVPVMRETIECLRSIFTGA 131 P LA +++ASL R L +G+SS IV W+G P+ +R+T+ LR TG Sbjct 72 PALLAQQAATLASLAPGRFVLGIGSSSDTIVQRWNGIPFTEPYQRVRDTLRFLRKALTGE 131 Query 132 RVEYSGRHVNSRGFRLRGAAPDT-RIALGAFGPGMIRLAAQHADEVVLNLASPFRVGRVR 190 +V S + +GF+L P I L A PGM+RLAA+ AD + N +P V VR Sbjct 132 KV--SDEALGVQGFKLDAPPPQQPPIVLAALRPGMLRLAAREADGAITNWLAPHDVRTVR 189 Query 191 AAIDSAAAAAGRAAPRLTVCVPVAVNPGAAAHSQLAAQLAVYLAPPGYGEMFSALGF-DG 249 + RL VC + A + +A Y+ P Y LG D Sbjct 190 GVLGEEPELLA----RLFVC---PTDDAEKARATGRWMIAAYMNVPVYRAFHQWLGRGDA 242 Query 250 L--VRSARSRATRRELAVAVPSELLDRVCALGSPDRVAARLRAYADAG--ADCVAVVPAT 305 L + A R+ A+P E++D + GSP R+R Y +AG +AVVP + Sbjct 243 LKPMNDAWDAGDRKAALEAIPDEVVDDLIVHGSPAACRDRIRQYVEAGLTTPILAVVPGS 302 Query 306 AEDPGGRVALRALRP 320 P A+RAL P Sbjct 303 GMSP--LEAVRALAP 315 >gi|296271475|ref|YP_003654107.1| luciferase-like monooxygenase [Thermobispora bispora DSM 43833] gi|296094262|gb|ADG90214.1| Luciferase-like monooxygenase [Thermobispora bispora DSM 43833] Length=318 Score = 103 bits (257), Expect = 4e-20, Method: Compositional matrix adjust. Identities = 94/307 (31%), Positives = 131/307 (43%), Gaps = 11/307 (3%) Query 18 EATDVALAAADTGFAALWIGEMATYDAFALATSIGLRTPNMTLKVGPLAVGVRGPVGLAL 77 E+ V A+ G+ W E+ D P + L + V RGP LA+ Sbjct 17 ESKQVISELAELGYTDAWSAEVNGTDGLIPLALAADWAPTLRLGSAIVPVYTRGPALLAM 76 Query 78 GVSSVASLTGCRVDLALGASSPAIVAGWHGRPWAHHVPVMRETIECLRSIFTGARVEYSG 137 +++A L R L +G SS IV W+G +A +R+T+ LR TG ++ Sbjct 77 SAATLADLAPGRFVLGIGTSSKVIVERWNGGEFAKPYARVRDTLRFLRDALTGKKITQRY 136 Query 138 RHVNSRGFRL-RGAAPDTRIALGAFGPGMIRLAAQHADEVVLNLASPFRVGRVRAAIDSA 196 GFRL R A +IAL A PGM+RLAA+ AD + N+ SP V +VRA + Sbjct 137 ETFEVDGFRLERPPAVPPKIALAALRPGMLRLAAREADAAITNMLSPQDVRKVRAEV--- 193 Query 197 AAAAGRAAPRLTVCVPVAVNPGAAAHSQLAAQLAVYLAPPGYGEMFSALGFDGLVRSARS 256 A R+ V V A +L LA YL P Y LG +R + Sbjct 194 -GADTELIARIFVVVTEDRERARAIGRRL---LAGYLTVPVYAAFHEWLGRGEALRRMQE 249 Query 257 R---ATRRELAVAVPSELLDRVCALGSPDRVAARLRAYADAGADCVAVVPATAEDPGGRV 313 RR A+P E++D + G P AR+R Y +G D + P D Sbjct 250 LWAAGDRRGAVEAIPDEVVDDLIVHGDPATCRARIREYVASGLDTPVLAPLLGADVPVAQ 309 Query 314 ALRALRP 320 A+R L P Sbjct 310 AVRDLAP 316 >gi|271970470|ref|YP_003344666.1| coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase-like protein [Streptosporangium roseum DSM 43021] gi|270513645|gb|ACZ91923.1| Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase-like protein [Streptosporangium roseum DSM 43021] Length=322 Score = 102 bits (255), Expect = 7e-20, Method: Compositional matrix adjust. Identities = 101/328 (31%), Positives = 144/328 (44%), Gaps = 26/328 (7%) Query 6 VALPFWLDRPDHEATDVALAAADTGFAALWIGEMATYDAFALATSIGLRTPNMTLKVGPL 65 + +PF+ DR E+ ++ G+ +W E+ D F P + L + Sbjct 9 MTVPFY-DRTLAESRELVAELPALGYTDVWSAEVNGVDGFVPLALAAEWAPGVRLGSAIV 67 Query 66 AVGVRGPVGLALGVSSVASLTGCRVDLALGASSPAIVAGWHGRPWAHHVPVMRETIECLR 125 V RGP LA+ +++A L R L +GASSPAIV W+ + R+T+ L+ Sbjct 68 PVSTRGPGLLAMSAATLADLAPERFVLGIGASSPAIVERWNAGEFVKPFARTRDTLRFLK 127 Query 126 SIFTGARVEYSGRHVNSRGFRL-RGAAPDTRIALGAFGPGMIRLAAQHADEVVLNLASPF 184 G +V +GFRL R +I L A P M+RLAA+ AD + N SP Sbjct 128 KALAGEKVTERYETFEVKGFRLERAPKVPPKIVLAALRPRMLRLAAEEADGAITNWLSPQ 187 Query 185 RVGRVRAAI--DSAAAAAGRAAPRLTVCVPVAVNPGAAAHSQLAAQ-LAVYLAPPGYGEM 241 V +VR+ I D+ A RL VC V+ A +L + LA YL P Y Sbjct 188 DVRKVRSEIGPDTELIA------RLFVC----VSEDAEKVRELGRRMLAGYLTVPVYAAF 237 Query 242 FSALGFDGLVR---SARSRATRRELAVAVPSELLDRVCALGSPDRVAARLRAYADAGADC 298 LG ++R A + R+ A+P E++D + G AR+R Y D G Sbjct 238 HEWLGRGEVLRPMHEAWAAGDRQTALRAIPDEVVDALIVHGDAATCRARIRQYVDNG--- 294 Query 299 VAVVPATAEDPGGRV----ALRALRPGG 322 P A PGG V A+R L P G Sbjct 295 -LTTPVLAPIPGGGVPISQAVRDLAPTG 321 >gi|16554492|ref|NP_444216.1| flavin-dependent oxidoreductase [Halobacterium sp. NRC-1] gi|169236107|ref|YP_001689307.1| alkanesulfonate monooxygenase [Halobacterium salinarum R1] gi|167727173|emb|CAP13959.1| monooxygenase (homolog to alkanesulfonate monooxygenase) [Halobacterium salinarum R1] Length=338 Score = 102 bits (253), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 97/316 (31%), Positives = 140/316 (45%), Gaps = 19/316 (6%) Query 1 MTDIEVALPFWLDRPDHEATDVALAAADTGFAALWIGEMATYDAFALATSIGLRTPNMTL 60 MT V LP + TD+A A G+ +W E DA T+I RT ++ + Sbjct 1 MTRRTVHLPVAAQDSLADITDIAERAETLGYDRVWFPETWGRDAATTLTAIADRTTDIGI 60 Query 61 KVGPLAVGVRGPVGLALGVSSVASLTGCRVDLALGASSPAIVAGWHGRPWAHHVPVMRET 120 + R P + +++ +G R L +G S PA++ GWHG+ + + RE Sbjct 61 GTSIINTYSRSPALVGQTAATLQEHSGGRFRLGMGPSGPAVIQGWHGQSFERPLRRTREY 120 Query 121 IECLRSIFTGARVEYSGRHVNSRGFRLRGAAPD--TRIALGAFGPGMIRLAAQHAD--EV 176 I+ +R++ TG V+Y G + ++GFRLR APD I + GP + LA + AD Sbjct 121 IDVVRAVLTGDPVDYDGDLIQTQGFRLRQDAPDPAPAIDVTGMGPKAVELAGRFADGWHA 180 Query 177 VLNLASPF--RVGRVRAAIDSAAAAAGRAAPRLTVCVPVAVNPGAAAHSQLAAQ-LAVYL 233 +L A R+ +R +D A A + T+ VP P AAA L Q LA Y+ Sbjct 181 LLFTADGIRERLADLRRGMDLGDRDAD--AVQTTLVVPCCAQPDAAAARDLTRQHLAFYV 238 Query 234 APPGYGEMF-SALGFDGL------VRSARSRATRRELAVAVPSELLDRVCALGSPDRVAA 286 G GE + +L G V A V +LLD A G+ V Sbjct 239 G--GMGEFYRDSLARQGYEAPATDVYDAWQDGDHERAVGLVTDDLLDAFAAAGTQADVRD 296 Query 287 RLRAYAD-AGADCVAV 301 RL A+A G D VAV Sbjct 297 RLAAFAGIDGVDAVAV 312 >gi|300710887|ref|YP_003736701.1| N5N10-methylenetetrahydromethanopterin reductase [Halalkalicoccus jeotgali B3] gi|299124570|gb|ADJ14909.1| N5N10-methylenetetrahydromethanopterin reductase [Halalkalicoccus jeotgali B3] Length=332 Score = 100 bits (250), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 85/287 (30%), Positives = 128/287 (45%), Gaps = 11/287 (3%) Query 26 AADTGFAALWIGEMATYDAFALATSIGLRTPNMTLKVGPLAVGVRGPVGLALGVSSVASL 85 A TG+ +W+ E DA + I RT ++ L L V R P + +++ + Sbjct 26 AERTGYDRVWLPETWGRDAATVLAVIAERTDSVGLGASILPVYSRSPALIGQTAATLQEV 85 Query 86 TGCRVDLALGASSPAIVAGWHGRPWAHHVPVMRETIECLRSIFTGARVEYSGRHVNSRGF 145 + R L +G S PA++ GWHG + + RET+E +R + +G RVEY G GF Sbjct 86 SEGRFRLGIGPSGPAVIEGWHGESFERPLKRTRETVEIVRRVLSGERVEYDGEIFGLSGF 145 Query 146 RLRGAAPDTR--IALGAFGPGMIRLAAQHADEVVLNLASPFRVGRVRAAIDSAAAAAGR- 202 RLR P+T I + GP + LA + D + +P + A ++ A R Sbjct 146 RLRSDPPETAPGIDVAGLGPKSVELAGRFGDGWHAVVFTPDGIRDRLADLERGAELGDRD 205 Query 203 -AAPRLTVCVPVAVNPGAAAHSQLAAQ-LAVYLAPPG--YGEMFSALGFD---GLVRSAR 255 A R T+ + +LA Q A Y+ G Y E + G++ V SA Sbjct 206 PAELRTTLSLTCCALADRERARELARQHTAFYVGGMGTYYRESLARQGYEEEANAVASAW 265 Query 256 SRATRRELAVAVPSELLDRVCALGSPDRVAARLRAY-ADAGADCVAV 301 R A+P ELLD +CA G+P+ + + A G D VAV Sbjct 266 GSGDREAALAAIPDELLDDLCAAGTPEEARETIERFEAVEGLDAVAV 312 >gi|284166171|ref|YP_003404450.1| 5,10-methylenetetrahydromethanopterin reductase [Haloterrigena turkmenica DSM 5511] gi|284015826|gb|ADB61777.1| 5,10-methylenetetrahydromethanopterin reductase [Haloterrigena turkmenica DSM 5511] Length=333 Score = 100 bits (249), Expect = 3e-19, Method: Compositional matrix adjust. Identities = 88/331 (27%), Positives = 136/331 (42%), Gaps = 11/331 (3%) Query 1 MTDIEVALPFWLDRPDHEATDVALAAADTGFAALWIGEMATYDAFALATSIGLRTPNMTL 60 MTD +V LP D A + G+ W+ E D + T++ RT + + Sbjct 1 MTDRDVHLPVAAQPTVDSIVDYTQRAEEGGYDCAWLPETWGRDGATVLTAMAERTAEIDI 60 Query 61 KVGPLAVGVRGPVGLALGVSSVASLTGCRVDLALGASSPAIVAGWHGRPWAHHVPVMRET 120 L R P L +++ ++ R L LG S P ++ WHG + + + RET Sbjct 61 GSSILNTYSRSPALLGQTAATLQEVSDGRFRLGLGPSGPVVIENWHGMEYGNPLRRTRET 120 Query 121 IECLRSIFTGARVEYSGRHVNSRGFRLRGAAPDTR--IALGAFGPGMIRLAAQHADEVVL 178 +E +R + +G V+Y G GFRLR APD + + + GP + LA + AD Sbjct 121 VEIVRQVLSGETVDYDGDDFQLSGFRLRCEAPDPQPPVEVTGMGPKAVELAGRFADGWHG 180 Query 179 NLASPFRVGRVRAAIDSAAAAAGRAAPRLTVCVPV---AVNPGAAAHSQLAAQLAVYLAP 235 + +P + I+ A R + V V A+ A +A Y+ Sbjct 181 IMLTPEGMADRIEDIERGADLGDRDPDEVQVTAGVTCCALEDTERARELARQHVAFYVGG 240 Query 236 PG--YGEMFSALGFD--GLVRSARSRATRRELAVAVPSELLDRVCALGSPDRVAARLRAY 291 G Y + G+D G + A R V +L+ +CA G P+ RL Y Sbjct 241 MGTFYRDALERQGYDAAGEIHDAWQAGDRERALELVDETVLEDLCAFGDPETARERLERY 300 Query 292 -ADAGADCVAV-VPATAEDPGGRVALRALRP 320 A G D VAV P A++ R + A+ P Sbjct 301 EAVDGIDAVAVSFPRGADEDEIRRTMDAVAP 331 >gi|183980369|ref|YP_001848660.1| coenzyme F420-dependent oxidoreductase [Mycobacterium marinum M] gi|183173695|gb|ACC38805.1| coenzyme F420-dependent oxidoreductase [Mycobacterium marinum M] Length=352 Score = 100 bits (248), Expect = 4e-19, Method: Compositional matrix adjust. Identities = 93/315 (30%), Positives = 137/315 (44%), Gaps = 24/315 (7%) Query 14 RPDHEATDVALAAADTGFAALWIGEMATYDAFALATSIGLRTPNMTLKVGPLAVGVRGPV 73 + + D + A G W+ E DA + I RT M L G L VG R PV Sbjct 16 KDGKDVVDFVVEAEKLGLHTCWVAEAWGSDAPSALGYIAARTERMQLGSGVLQVGTRSPV 75 Query 74 GLALGVSSVASLTGCRVDLALGASSPAIVAGWHGRPWAHHVPVMRETIECLRSIFTGARV 133 +A ++++L+ R L LGAS P ++ G HG + + ++ET+E +R +F G +V Sbjct 76 LVAQTAITLSNLSCGRFLLGLGASGPQVIEGLHGVAFDRPLARLKETVEIVRQVFAGGKV 135 Query 134 EYSGR--HVNSRGFRLRGAAPDTR------IALGAFGPGMIRLAAQHADEVVLNLASPFR 185 YSG + RG R TR I L A P M+RL + AD + P Sbjct 136 TYSGSEFQIPRRGGEARPMRLSTRPEYDIPIYLAALSPAMLRLTGRIADGWLGTSFVPEG 195 Query 186 VGRVR-AAIDSAAAAAGRAAPRLTVC--VPVAVNPGAAAHSQLAA----QLAVYLAPPG- 237 G +D+ AAAGR+ + C VA G + A +LA L G Sbjct 196 AGDAYFTHLDAGLAAAGRSRADIDFCQGAEVAFASGVEELRDMVAARKTELAFSLGGMGS 255 Query 238 -----YGEMFSALGFDGL---VRSARSRATRRELAVAVPSELLDRVCALGSPDRVAARLR 289 Y + +S G+ + VR R R A V E++ +G+ + V +RL Sbjct 256 ASTNYYNQAYSRQGWSEVAAAVRERWQRGDREGAARLVTDEMVLATTLIGTEEMVRSRLV 315 Query 290 AYADAGADCVAVVPA 304 A+ DAG + V + PA Sbjct 316 AWRDAGVNTVRLYPA 330 >gi|118619837|ref|YP_908169.1| coenzyme F420-dependent oxidoreductase [Mycobacterium ulcerans Agy99] gi|118571947|gb|ABL06698.1| coenzyme F420-dependent oxidoreductase [Mycobacterium ulcerans Agy99] Length=349 Score = 99.8 bits (247), Expect = 6e-19, Method: Compositional matrix adjust. Identities = 93/315 (30%), Positives = 137/315 (44%), Gaps = 24/315 (7%) Query 14 RPDHEATDVALAAADTGFAALWIGEMATYDAFALATSIGLRTPNMTLKVGPLAVGVRGPV 73 + + D + A G W+ E DA + I RT M L G L VG R PV Sbjct 13 KDGKDTVDFVVEAEKLGLHTCWVAEAWGSDAPSALGYIAARTERMQLGSGVLQVGTRSPV 72 Query 74 GLALGVSSVASLTGCRVDLALGASSPAIVAGWHGRPWAHHVPVMRETIECLRSIFTGARV 133 +A ++++L+ R L LGAS P ++ G HG + + ++ET+E +R +F G +V Sbjct 73 LVAQTAITLSNLSCGRFLLGLGASGPRVIEGLHGVAFDRPLARLKETVEIVRQVFAGGKV 132 Query 134 EYSGR--HVNSRGFRLRGAAPDTR------IALGAFGPGMIRLAAQHADEVVLNLASPFR 185 YSG + RG R TR I L A P M+RL + AD + P Sbjct 133 TYSGSEFQIPRRGGEARPMRLSTRPEYDIPIYLAALSPAMLRLTGRIADGWLGTSFVPEG 192 Query 186 VGRVR-AAIDSAAAAAGRAAPRLTVC--VPVAVNPGAAAHSQLAA----QLAVYLAPPG- 237 G +D+ AAAGR+ + C VA G + A +LA L G Sbjct 193 AGDAYFTHLDAGLAAAGRSRADIDFCQGAEVAFASGVEELRDMVAARKTELAFSLGGMGS 252 Query 238 -----YGEMFSALGFDGL---VRSARSRATRRELAVAVPSELLDRVCALGSPDRVAARLR 289 Y + +S G+ + VR R R A V E++ +G+ + V +RL Sbjct 253 ASTNYYNQAYSRQGWSEVAAAVRERWQRGDREGAARLVTDEMVLATTLIGTEEMVRSRLV 312 Query 290 AYADAGADCVAVVPA 304 A+ DAG + V + PA Sbjct 313 AWRDAGVNTVRLYPA 327 >gi|317124875|ref|YP_004098987.1| F420-dependent oxidoreductase [Intrasporangium calvum DSM 43043] gi|315588963|gb|ADU48260.1| putative F420-dependent oxidoreductase [Intrasporangium calvum DSM 43043] Length=354 Score = 99.4 bits (246), Expect = 7e-19, Method: Compositional matrix adjust. Identities = 94/325 (29%), Positives = 140/325 (44%), Gaps = 31/325 (9%) Query 6 VALPFWLDRPD--HEATDVALAAADTGFAALWIGEMATYDAFALATSIGLRTPNMTLKVG 63 V L +W DRP H+ +A A G+ +LW+ E DA ++ IG T + L Sbjct 5 VNLGYW-DRPSAGHDMVAIAREADRLGYDSLWVAEAYGSDAPSMLAWIGALTERIHLGSA 63 Query 64 PLAVGVRGPVGLALGVSSVASLTGCRVDLALGASSPAIVAGWHGRPWAHHVPVMRETIEC 123 + + R P A+ +++ +++ R L LG S P + GWHG + + R+ +E Sbjct 64 VMQIPARTPALTAMTAATIDTMSQGRFRLGLGVSGPQVSEGWHGVRFTSPLGRTRDYVEI 123 Query 124 LRSIFTGARVEYSGRHVN-------SRGFRLRGAAP---DTRIALGAFGPGMIRLAAQHA 173 +RS R+ + G H + +L G+ P + + L A GP + L + A Sbjct 124 VRSALARERLTHPGPHYELPLPDGPGKALKL-GSRPLRSEVPVYLAAVGPRNLALTGEIA 182 Query 174 DEVVLNLASPFRVGRVRAAIDSAAAAAGRAAPR-------LTVCVPVA-VNPGAAAHSQL 225 D + SP + I A AAGR AP + PV V+ A A L Sbjct 183 DGWLAIFLSPEQAREEIRLIAEARQAAGRGAPEDPMAGFDVVSSTPVILVDDVAEAAGHL 242 Query 226 AAQLAVYLAPPG------YGEMFSALGFDGL---VRSARSRATRRELAVAVPSELLDRVC 276 A+YL G Y + +GF+ V+ RE A AVP + +D Sbjct 243 RDYCALYLGGMGSREQNFYNRLACRMGFEQEAADVQDLYLAGRHREAAAAVPLDFIDETA 302 Query 277 ALGSPDRVAARLRAYADAGADCVAV 301 LGSP RVA RL+ Y D G +AV Sbjct 303 LLGSPQRVARRLQRYEDVGVTTLAV 327 >gi|284034897|ref|YP_003384828.1| luciferase-like monooxygenase [Kribbella flavida DSM 17836] gi|283814190|gb|ADB36029.1| Luciferase-like monooxygenase [Kribbella flavida DSM 17836] Length=315 Score = 99.4 bits (246), Expect = 8e-19, Method: Compositional matrix adjust. Identities = 93/284 (33%), Positives = 130/284 (46%), Gaps = 15/284 (5%) Query 27 ADTGFAALWIGEMATYDAFALATSIGLRTPNMTLKVGPLAVGVRGPVGLALGVSSVASLT 86 AD G+ LW E+A DAF + L + V RGP LA+ +++A L Sbjct 25 ADLGYTDLWSAEVAGADAFTPLVLASEWDQRLRLGTAVVPVHTRGPAALAMSAAALAELA 84 Query 87 GCRVDLALGASSPAIVAGWHGRPWAHHVPVMRETIECLRSIFTGARVEYSGRHVNSRGFR 146 R L +GASS IV GW+G + + R+ + LR F G +V+ R FR Sbjct 85 PGRFVLGIGASSETIVTGWNGIAYDPPLARTRDVLRFLRQAFAGEKVDGEFDSFTIRRFR 144 Query 147 LRGAAPDT--RIALGAFGPGMIRLAAQHADEVVLNLASPFRVGRVRAAIDSAAAAAGRAA 204 L APD + L A P M+RLA + AD + N S V +VRA + A A Sbjct 145 LE-KAPDVPPAVMLAALRPQMLRLARREADGAITNWLSAQDVRQVRAELGDAKELAA--- 200 Query 205 PRLTVCVPVAVNPGAAAHSQLAAQLAVYLAPPGYGEMFSALGF-DGL--VRSARSRATRR 261 R+ VCV A + +A YL PGY LG + L +RSA + R Sbjct 201 -RIFVCV---TEDAEMARNIGRFLIATYLTVPGYAAFHDWLGRGEALQEMRSAWAAGDRN 256 Query 262 ELAVAVPSELLDRVCALGSPDRVAARLRAYADAGADC--VAVVP 303 AVP +++D + GS D A+++AY D G D +A +P Sbjct 257 AAMAAVPVQVIDELVVHGSADDCRAKIQAYVDNGLDTAIIATLP 300 >gi|76802821|ref|YP_330916.1| alkanesulfonate monooxygenase [Natronomonas pharaonis DSM 2160] gi|76558686|emb|CAI50278.1| monooxygenase (homolog to alkanesulfonate monooxygenase) 2 [Natronomonas pharaonis DSM 2160] Length=333 Score = 99.4 bits (246), Expect = 8e-19, Method: Compositional matrix adjust. Identities = 90/313 (29%), Positives = 136/313 (44%), Gaps = 15/313 (4%) Query 1 MTDIEVALPFWLDRPDHEATDVALAAADTGFAALWIGEMATYDAFALATSIGLRTPNMTL 60 M D ++ LP LD D + VA A G+ L + E+ D L ++ RT + L Sbjct 1 MVDRDIVLPSGLDSLD-DVVAVAQRAESLGYDRLSLPEVTGRDGVTLLATLAARTDRIGL 59 Query 61 KVGPLAVGVRGPVGLALGVSSVASLTGCRVDLALGASSPAIVAGWHGRPWAHHVPVMRET 120 + R P L +V +G R + LG SSP + GWH + + +RET Sbjct 60 SNDVFSPWGRSPAMLGQTGVTVQEASGGRYRMGLGTSSPNLTEGWHLAAYERPLRRLRET 119 Query 121 IECLRSIFTGARVEYSGRHVNSRGFRLRGAAPDTR-IALGAFGPGMIRLAAQHADEVVLN 179 I+ +R + G ++Y G H + G RLRG P + + + A GP + LA + AD V Sbjct 120 IDIIRQVTAGEELDYDGDHFDGGGLRLRGVEPRSVPVDVAALGPKAVELAGRFADGWVPQ 179 Query 180 LASPFRVGRVRAAIDSAAAAAGRAAPRLTVCVPV-------AVNPGAAAHSQLAAQLAVY 232 L + + + AA R+ L V V V A AA QLA + Y Sbjct 180 LFTVAALEDRLEDLRRGAALGDRSTDDLRVAVTVRSCALEDASRARTAARKQLAFMVGAY 239 Query 233 LAPPGYGEMFSALGFDGL---VRSARSRATRRELAVAVPSELLDRVCALGSPDRVAARLR 289 P Y + + GF+ + A + R+ AV E++D + A G+P+ V +R Sbjct 240 --GPYYRQSIARQGFEAATDDIHGAWTDGDRQRAIEAVTEEMVDSLVAAGTPEAVRETVR 297 Query 290 AY-ADAGADCVAV 301 Y A G D V + Sbjct 298 RYEAVDGVDAVRI 310 >gi|289580736|ref|YP_003479202.1| 5,10-methylenetetrahydromethanopterin reductase [Natrialba magadii ATCC 43099] gi|289530289|gb|ADD04640.1| 5,10-methylenetetrahydromethanopterin reductase [Natrialba magadii ATCC 43099] Length=336 Score = 98.6 bits (244), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 85/311 (28%), Positives = 138/311 (45%), Gaps = 10/311 (3%) Query 1 MTDIEVALPFWLDRPDHEATDVALAAADTGFAALWIGEMATYDAFALATSIGLRTPNMTL 60 MT+ +V LP + A A G+ W+ E DA + T+I RT + L Sbjct 1 MTERDVHLPVAAQPSVDSLVEYAQTAEAGGYDCAWLPETWGRDAVTVLTAIAERTDEIDL 60 Query 61 KVGPLAVGVRGPVGLALGVSSVASLTGCRVDLALGASSPAIVAGWHGRPWAHHVPVMRET 120 + R P L +++ ++ R L LG S P ++ WHG + + + RET Sbjct 61 GSSIVNTYSRSPALLGQTAATLQEVSDGRFRLGLGPSGPVVIENWHGIEYGNPLKRTRET 120 Query 121 IECLRSIFTGARVEYSGRHVNSRGFRLRGAAPDTR--IALGAFGPGMIRLAAQHADEVVL 178 ++ +R++ +G VEY G + + GFRLR PD + + GP + LA + AD Sbjct 121 VDIVRAVLSGEPVEYDGDYFSLSGFRLRCEVPDPSPPVEVTGMGPKAVELAGRFADGWHG 180 Query 179 NLASPFRVGRVRAAIDSAAAAAGRAAPRLTVCVPV---AVNPGAAAHSQLAAQLAVYLAP 235 + +P V I+ A R + V + V A++ + A A Y+ Sbjct 181 IMLTPEGVADRIEDIERGADLGDRDPDDVQVTIGVTCCALDDASRARDLARQHTAFYIGG 240 Query 236 PG--YGEMFSALGFDGLVRSARS-RATRRELAVAVPSE-LLDRVCALGSPDRVAARLRAY 291 G Y + G+D + +A RE A+++ E +LD +CA G+P+ V ++ Y Sbjct 241 MGTFYRDALERQGYDEASEIHNAWQAGDRERALSLVDEAILDDLCAAGTPEDVREQVERY 300 Query 292 -ADAGADCVAV 301 A G D VAV Sbjct 301 EAVDGIDAVAV 311 >gi|298243661|ref|ZP_06967468.1| 5,10-methylenetetrahydromethanopterin reductase [Ktedonobacter racemifer DSM 44963] gi|297556715|gb|EFH90579.1| 5,10-methylenetetrahydromethanopterin reductase [Ktedonobacter racemifer DSM 44963] Length=359 Score = 98.6 bits (244), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 78/297 (27%), Positives = 134/297 (46%), Gaps = 16/297 (5%) Query 17 HEATDVALAAADTGFAALWIGEMATYDAFALATSIGLRTPNMTLKVGPLAVGVRGPVGLA 76 +E + A + GF ++W+GE Y+ F + T + + G + R P +A Sbjct 35 NEIVEKVRLADELGFDSVWLGESWGYELFTSMGDLLRATKRIKVGAGIANIYSRTPALIA 94 Query 77 LGVSSVASLTGCRVDLALGASSPAIVAGWHGRPWAHHVPVMRETIECLRSIFTGARVEYS 136 ++++ +G R L LG S ++ WHG + + E ++ +R I G ++ Y+ Sbjct 95 STIATLDERSGGRALLGLGPSGANVIEHWHGVKFEKPLKRTHEYVDIIRMILRGEKLAYT 154 Query 137 GRHVN-SRGFRLRGAA--PDTRIALGAFGPGMIRLAAQHADEVVLNLASPFRVGRVRAAI 193 G RGF+LR D I + A GP I + D ++ + G +RA + Sbjct 155 GEFFQLERGFKLRFTPLRADIPIYIAAMGPKNISQTGEIGDGILPVYWPVEKFGEMRAQL 214 Query 194 DSAAAAAGRAAPRLTVC--VPVAVNPGAAAHSQL-------AAQLAVYLAPPG--YGEMF 242 D ++ AGR A + + + A+ P A+ Q+ A+ LA Y+ G Y +M Sbjct 215 DESSQQAGRPAHSVAIAPYITTALLPEGASEQQILSARRAAASPLAYYIGKMGVYYAQML 274 Query 243 SALGFDGLVRSARSRATR--RELAVAVPSELLDRVCALGSPDRVAARLRAYADAGAD 297 S G+ V++ + + + AV +LD V +G+P V ARL +AD G D Sbjct 275 SRHGYTEDVQAVLAGWEKGMKTAIEAVSPRMLDAVSIVGTPREVVARLDQWADLGVD 331 >gi|300786515|ref|YP_003766806.1| coenzyme F420-dependent N5,N10-methenyltetrahydromethanopterin reductase [Amycolatopsis mediterranei U32] gi|299796029|gb|ADJ46404.1| coenzyme F420-dependent N5,N10-methenyltetrahydromethanopterin reductase [Amycolatopsis mediterranei U32] gi|340527995|gb|AEK43200.1| coenzyme F420-dependent N5,N10-methenyltetrahydromethanopterin reductase [Amycolatopsis mediterranei S699] Length=345 Score = 98.2 bits (243), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 93/338 (28%), Positives = 139/338 (42%), Gaps = 22/338 (6%) Query 8 LPFWLDRPDHEATDVALAAADTGFAALWIGEMATYDAFALATSIGLRTPNMTLKVGPLAV 67 L +W D +A A D G+A +W E DA + + I RT + + L + Sbjct 7 LGYWGSGNDPANLALAKQAEDLGYAVVWAAEAYGSDAVTVLSWIAARTSRIDVGAAVLQI 66 Query 68 GVRGPVGLALGVSSVASLTGCRVDLALGASSPAIVAGWHGRPWAHHVPVMRETIECLRSI 127 R P A+ +++ +L+G R L LG S P + GWHG + V RE +R+ Sbjct 67 PARTPAMTAMTAATLDTLSGGRFRLGLGVSGPQVSEGWHGVRFTSPVGRTREYAAVVRTA 126 Query 128 FTGARVEYSGRHVN-------SRGFRL--RGAAPDTRIALGAFGPGMIRLAAQHADEVVL 178 R+++ G H + RL R A + L A GP + LA + AD + Sbjct 127 LRRERLKFEGEHFTLPLPDGPGKALRLTVRPARKHIPLYLAAIGPKNLELAGEIADGWLP 186 Query 179 NLASPFRVGRVRAAIDSAAAAAGRAAPRLTVCVPVAVNPGAAAHS---QLAAQLAVYLAP 235 SP G A + + A AGR V V + PG + + A+YL Sbjct 187 VFFSPAHAGEQLAHVRAGAGRAGRTLDGFDVVPSVPLVPGDDWRTCADAVRGYAALYLGG 246 Query 236 PG------YGEMFSALGFDGLVRSARSR---ATRRELAVAVPSELLDRVCALGSPDRVAA 286 G Y + +GF + + R AVP E LD LG +R+A Sbjct 247 MGSKEKNFYNRLACRMGFAAEAAEVQEKYLAGDRAGAMAAVPPEFLDATSLLGPKERIAE 306 Query 287 RLRAYADAGADCVAVVPATAEDPGG-RVALRALRPGGL 323 ++ YA+AG ++V P T E R A+ AL G+ Sbjct 307 KMTEYAEAGVTTLSVSPYTPEPAAALRTAVEALELAGV 344 >gi|330468968|ref|YP_004406711.1| luciferase-like, subgroup [Verrucosispora maris AB-18-032] gi|328811939|gb|AEB46111.1| luciferase-like, subgroup [Verrucosispora maris AB-18-032] Length=321 Score = 98.2 bits (243), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 94/290 (33%), Positives = 130/290 (45%), Gaps = 16/290 (5%) Query 16 DHEATDVALAAADTGFAALWIGEMATYDAFALATSIGLRTPNMTLKVGPLAVGVRGPVGL 75 DH A ALA D GF LW E+ DAF T + P + L V RGP L Sbjct 12 DHAAVYEALA--DAGFTDLWSSEVNGVDAFTPLTLAAVWQPGLRLGTAVTPVFTRGPGLL 69 Query 76 ALGVSSVASLTGCRVDLALGASSPAIVAGWHGRPWAHHVPVMRETIECLRSIFTGARVEY 135 A+ +++A + R L +GASSP +V+ W+ + R+ + LR+ G V+ Sbjct 70 AMSAAALADVAPGRFALGIGASSPVVVSDWNAVEFTEPFRRTRDVLRFLRAALRGETVDG 129 Query 136 SGRHVNSRGFRL-RGAAPDTRIALGAFGPGMIRLAAQHADEVVLNLASPFRVGRVRAAID 194 + R F L R A + LGA PGM+RLAA AD V+LN + V R Sbjct 130 AFDTFAVRRFSLQRPPAVPPPLLLGALRPGMLRLAAAEADGVILNWLAATDVPR------ 183 Query 195 SAAAAAGRAAPRLTVCVPVAVNP---GAAAHSQLAAQLAVYLAPPGYGEMFSALGFD--- 248 A A G P+ V + V P A + + YL P Y E LG Sbjct 184 -AVAELGERRPQFEVVARIFVCPTEDAGYARTLGRRMITSYLTVPAYAEFHRWLGRQEAL 242 Query 249 GLVRSARSRATRRELAVAVPSELLDRVCALGSPDRVAARLRAYADAGADC 298 + A + RR AVP E++D + GSP++ A++R YA+AG D Sbjct 243 SAMWEAWAAGDRRAALAAVPDEVVDALIVHGSPEQCRAKVRRYAEAGVDV 292 >gi|300784594|ref|YP_003764885.1| luciferase family protein [Amycolatopsis mediterranei U32] gi|299794108|gb|ADJ44483.1| luciferase family protein [Amycolatopsis mediterranei U32] gi|340526016|gb|AEK41221.1| luciferase family protein [Amycolatopsis mediterranei S699] Length=316 Score = 97.1 bits (240), Expect = 4e-18, Method: Compositional matrix adjust. Identities = 90/299 (31%), Positives = 130/299 (44%), Gaps = 16/299 (5%) Query 28 DTGFAALWIGEMATYDAFALATSIGLRTPNMTLKVGPLAVGVRGPVGLALGVSSVASLTG 87 D G+ W E A DAF P + L + V RGP LA+ ++VA L Sbjct 27 DLGYTDAWTAETAGTDAFTPLVLASQWAPQLRLGTAIVPVYTRGPGLLAMQAATVAELAP 86 Query 88 CRVDLALGASSPAIVAGWHGRPWAHHVPVMRETIECLRSIFTGARVEYSGRHVNSRGFRL 147 R L +GASSP IV+ W+ + R+T+ LRS G +V FRL Sbjct 87 GRFVLGIGASSPVIVSQWNAASFDEPFARSRDTLRFLRSALAGEKVSEKYETFAVSKFRL 146 Query 148 -RGAAPDTRIALGAFGPGMIRLAAQHADEVVLNLASPFRVGRVRAAIDSAAAAAGRAAPR 206 R P I L A PGM+RLAA+ AD + N + V +VR+ + A R Sbjct 147 ERPTDPPPSIMLAALRPGMLRLAAREADGAITNWLAASDVPQVRSVVGPDVELAA----R 202 Query 207 LTVCVPVAVNPGAAAHSQLAAQLAVYLAPPGYGEMFSALGF-DGL--VRSARSRATRREL 263 + VC AA ++ YL P Y LG + L + A + R++ Sbjct 203 IFVC---PTEDAEAARGLGRMLISSYLTVPVYAAFHEWLGRGEALAPMHEAWAAGDRQKA 259 Query 264 AVAVPSELLDRVCALGSPDRVAARLRAYADAG--ADCVAVVPATAEDPGGRVALRALRP 320 +P ++D + GS D ++++Y D G +A++P T EDP +V R L P Sbjct 260 NQVIPDSVVDELVIHGSVDSCREQVQSYVDNGLTTPIIALLP-TGEDPFEQV--RGLAP 315 >gi|315428016|dbj|BAJ49605.1| FMN-dependent monooxygenase [Candidatus Caldiarchaeum subterraneum] Length=329 Score = 96.3 bits (238), Expect = 6e-18, Method: Compositional matrix adjust. Identities = 93/321 (29%), Positives = 138/321 (43%), Gaps = 25/321 (7%) Query 12 LDRPDHEATDVALAAADTGFAALWIGE-MATYDAFALATSIGLRTPNMTLKVGPLAVGVR 70 +D + +VA A + G+++LW+ E M+ LA + L T + L L + R Sbjct 14 VDLTPQQFIEVAKRAEELGYSSLWMTEEMSRASPITLAAA-ALHTKRIKLGAAILNIFAR 72 Query 71 GPVGLALGVSSVASLTGCRVDLALGASSPAIVAGWHGRPWAHHVPVMRETIECLRSIFTG 130 P+ A+ +++ L+ R L LG P I HG ++ V M E IE +R TG Sbjct 73 TPMATAMETATLQELSQNRFILGLGVGGPDISRKGHGADISNPVQKMSEYIEIVRKFLTG 132 Query 131 ARVEYSGRHVNSRGFRLRGAAPD-TRIALGAFGPGMIRLAAQHADEVVLNLASPFRVGRV 189 R+ Y+GRH G RL P T I L A P M+ LA AD ++LNL P V Sbjct 133 ERLNYAGRHYRVDGVRLWIKQPRPTEIYLAALNPQMLTLAGAKADGLILNLFDPRAAEYV 192 Query 190 RAAIDSAAAAA---GRAAPRLTVCVPVAVNPGAAAHSQLAAQLAVYLAPPGYGEMFSALG 246 AI+ + R + + + A + S L +A YL+ P Y + G Sbjct 193 HKAINKGLKNSHDQNRPFKKFSFVL-AAASSEPEYFSALKRSVAFYLSSPAYRRIMREAG 251 Query 247 F-DGLVRSARSRATR-RELAV-AVPSELLDRVCALGSPDRVAARLRAYADAGADCVAVVP 303 + + R A TR RE AV + ++++ V + D V+ +L Y AG V P Sbjct 252 HGEAVERFATVLETRGREAAVETIDDDVVESVSVICDRD-VSDQLERYRKAG-----VTP 305 Query 304 ATAEDPGGRVALRALRPGGLY 324 P RPG Y Sbjct 306 LIYPQP---------RPGNEY 317 >gi|315426661|dbj|BAJ48287.1| FMN-dependent monooxygenase [Candidatus Caldiarchaeum subterraneum] gi|343485427|dbj|BAJ51081.1| FMN-dependent monooxygenase [Candidatus Caldiarchaeum subterraneum] Length=331 Score = 95.9 bits (237), Expect = 7e-18, Method: Compositional matrix adjust. Identities = 93/321 (29%), Positives = 138/321 (43%), Gaps = 25/321 (7%) Query 12 LDRPDHEATDVALAAADTGFAALWIGE-MATYDAFALATSIGLRTPNMTLKVGPLAVGVR 70 +D + +VA A + G+++LW+ E M+ LA + L T + L L + R Sbjct 16 VDLTPQQFIEVAKRAEELGYSSLWMTEEMSRASPITLAAA-ALHTKRIKLGAAILNIFAR 74 Query 71 GPVGLALGVSSVASLTGCRVDLALGASSPAIVAGWHGRPWAHHVPVMRETIECLRSIFTG 130 P+ A+ +++ L+ R L LG P I HG ++ V M E IE +R TG Sbjct 75 TPMATAMEAATLQELSQNRFILGLGVGGPDISRKGHGADISNPVQKMSEYIEIVRKFLTG 134 Query 131 ARVEYSGRHVNSRGFRLRGAAPD-TRIALGAFGPGMIRLAAQHADEVVLNLASPFRVGRV 189 R+ Y+GRH G RL P T I L A P M+ LA AD ++LNL P V Sbjct 135 ERLNYAGRHYRVDGVRLWIKQPRPTEIYLAALNPQMLTLAGAKADGLILNLFDPRAAEYV 194 Query 190 RAAIDSAAAAA---GRAAPRLTVCVPVAVNPGAAAHSQLAAQLAVYLAPPGYGEMFSALG 246 AI+ + R + + + A + S L +A YL+ P Y + G Sbjct 195 HKAINKGLKNSHDQNRPFKKFSFVL-AAASSEPEYFSALKRSVAFYLSSPAYRRIMREAG 253 Query 247 F-DGLVRSARSRATR-RELAV-AVPSELLDRVCALGSPDRVAARLRAYADAGADCVAVVP 303 + + R A TR RE AV + ++++ V + D V+ +L Y AG V P Sbjct 254 HGEAVERFATVLETRGREAAVETIDDDVVESVSVICDRD-VSDQLERYRKAG-----VTP 307 Query 304 ATAEDPGGRVALRALRPGGLY 324 P RPG Y Sbjct 308 LIYPQP---------RPGNEY 319 >gi|302529664|ref|ZP_07282006.1| 5,10-methylenetetrahydromethanopterin reductase [Streptomyces sp. AA4] gi|302438559|gb|EFL10375.1| 5,10-methylenetetrahydromethanopterin reductase [Streptomyces sp. AA4] Length=346 Score = 95.9 bits (237), Expect = 7e-18, Method: Compositional matrix adjust. Identities = 90/309 (30%), Positives = 131/309 (43%), Gaps = 28/309 (9%) Query 21 DVALAAADTGFAALWIGEMATYDAFALATSIGLRTPNMTLKVGPLAVGVRGPVGLALGVS 80 D L A G W+ E D ++ + RT + L G + +GVR PV A Sbjct 19 DFVLEAEKLGLGECWVAEAWGSDGPSVLGYLAARTDRIRLGSGIMQLGVRTPVAAAQAAL 78 Query 81 SVASLTGCRVDLALGASSPAIVAGWHGRPWAHHVPVMRETIECLRSIFTGARVEYSGRHV 140 ++A ++G R L LGAS P +V G HG P+A + MRET++ +RS F G ++ ++G+ Sbjct 79 TLAEMSGGRFALGLGASGPQVVEGLHGVPFARPLTRMRETVQIIRSAFAGEKISFAGKAF 138 Query 141 N------SRGFRLRGA-APDTRIALGAFGPGMIRLAAQHADEVVLNLASPFRVGRVRAAI 193 SR RL A D I L P M+ L + AD + P + Sbjct 139 QIPLPGESRPMRLSTAPNEDIPIYLATLSPRMLELTGELADGWLGTSFVPEGADAYFRHL 198 Query 194 DSAAAAAGRAAPRLTVCVPVAV---------NPGAAAHSQLAAQLAVYLAPPG------Y 238 D+ A AGR+ L VC V P A + +LA L G Y Sbjct 199 DAGLAKAGRSRGDLVVCQGAEVAFASDEDELRPMVAGRKK---ELAFSLGGMGSASTNFY 255 Query 239 GEMFSALGFDGLVRSARSR---ATRRELAVAVPSELLDRVCALGSPDRVAARLRAYADAG 295 + + G+ + R R R A V E++ +G+ D V ARL+ + AG Sbjct 256 HDAYRRQGWADVAAEVRQRWQSGDRDGAAGLVTDEMVLATTLIGTEDMVRARLKVWRAAG 315 Query 296 ADCVAVVPA 304 D V + PA Sbjct 316 VDTVRLYPA 324 >gi|322369288|ref|ZP_08043853.1| N5N10-methylenetetrahydromethanopterin reductase [Haladaptatus paucihalophilus DX253] gi|320551020|gb|EFW92669.1| N5N10-methylenetetrahydromethanopterin reductase [Haladaptatus paucihalophilus DX253] Length=333 Score = 94.7 bits (234), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 83/313 (27%), Positives = 134/313 (43%), Gaps = 14/313 (4%) Query 21 DVALAAADTGFAALWIGEMATYDAFALATSIGLRTPNMTLKVGPLAVGVRGPVGLALGVS 80 D+ A + G+ W+ E DA T++ L T + L + V R P + + Sbjct 22 DLTRTAEELGYDHAWLPETWGRDAVTSLTAMALGTDEIGLGPSIVNVYSRSPALIGQTAA 81 Query 81 SVASLTGCRVDLALGASSPAIVAGWHGRPWAHHVPVMRETIECLRSIFTGARVEYSGRHV 140 ++ ++ R + +G S PA++ GWHG + + RETI+ +R + +G V Y G Sbjct 82 TLQEVSDGRFRVGIGPSGPAVIQGWHGEAFDRPLRRTRETIDIVRKVLSGETVNYDGDCF 141 Query 141 NSRGFRLRGAAPDT--RIALGAFGPGMIRLAAQHADEVVLNLASP----FRVGRVRAAID 194 GFRLR P+T I GP + LA + AD L +P R+ +R +D Sbjct 142 TLGGFRLRCDPPETPPPIDAAGMGPKSVELAGRFADGWHATLFTPDGMEDRLDDLRRGVD 201 Query 195 SAAAAAGRAAPRLTVCVPVAVNPGAAAHSQLAAQLAVYLAPPG--YGEMFSALGFDGL-- 250 L++ A++ G A + A Y+ G Y + + G++ + Sbjct 202 LGDRDEDDVEVTLSLTC-CALDDGERARTLARQHAAFYIGGMGTYYRDSLARQGYEDVAY 260 Query 251 -VRSARSRATRRELAVAVPSELLDRVCALGSPDRVAARLRAYAD-AGADCVAV-VPATAE 307 + +A + V +LLD + A G+P+R +AD G D VAV P A Sbjct 261 DISTAWGNGDKERATELVNDDLLDHLSAAGTPERAREEFEKFADIDGVDSVAVGSPRGAT 320 Query 308 DPGGRVALRALRP 320 R +RAL P Sbjct 321 VEEARETMRALAP 333 >gi|158314537|ref|YP_001507045.1| luciferase family protein [Frankia sp. EAN1pec] gi|158109942|gb|ABW12139.1| luciferase family protein [Frankia sp. EAN1pec] Length=359 Score = 94.7 bits (234), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 87/305 (29%), Positives = 133/305 (44%), Gaps = 25/305 (8%) Query 21 DVALAAADTGFAALWIGEMATYDAFALATSIGLRTPNMTLKVGPLAVGVRGPVGLALGVS 80 DVA A +G+ ++W E DAF I T + L + R P A+ V Sbjct 45 DVARRAERSGYDSVWTSEAWGSDAFTPLAYIAALTSRLRLGTAIAQMPARTPATTAMTVL 104 Query 81 SVASLTGCRVDLALGASSPAIVAGWHGRPWAHHVPVMRETIECLRSI--------FTGA- 131 ++ L+ RV L LGAS P +V GWHG P+ V + RE + LR F+GA Sbjct 105 TLQQLSQGRVLLGLGASGPQVVEGWHGVPYRPPVRMTREYLAVLRKALAATERLEFSGAI 164 Query 132 -RVEYSGRHVNSRGFRLRGAAP---DTRIALGAFGPGMIRLAAQHADEVVLNLASPFRVG 187 V Y+G +G LR P DT I + A GP + +A + AD ++ L SP R Sbjct 165 FTVPYTGPDSTGQGRPLRSTLPGAADTPILIAALGPKNVAMAVEEADGLLPYLWSPARWS 224 Query 188 RVRAAIDSAAAAAGRAAPRLTVCVPVAVNPGAAAHSQLAAQLAVYLAPPG------YGEM 241 + A + AP + CV ++ A +Q+ ++A+++ G Y + Sbjct 225 KAWGETLEKAPEGFQVAPTVLACVGDDLD---ACRNQVRPRIALHIGGMGSRSKNFYALL 281 Query 242 FSALGF---DGLVRSARSRATRRELAVAVPSELLDRVCALGSPDRVAARLRAYADAGADC 298 S G+ ++ R AVP EL+D + +G P R+A +L + D Sbjct 282 VSRYGYADEASRIQDLYLGGDRAAACAAVPDELVDDLALVGPPARIADQLAVWRDGPITT 341 Query 299 VAVVP 303 + V P Sbjct 342 LIVEP 346 >gi|302561524|ref|ZP_07313866.1| 5,10-methylenetetrahydromethanopterin reductase [Streptomyces griseoflavus Tu4000] gi|302479142|gb|EFL42235.1| 5,10-methylenetetrahydromethanopterin reductase [Streptomyces griseoflavus Tu4000] Length=351 Score = 93.6 bits (231), Expect = 4e-17, Method: Compositional matrix adjust. Identities = 87/324 (27%), Positives = 137/324 (43%), Gaps = 26/324 (8%) Query 6 VALPFWLDRPDHEATDVALAAADTGFAALWIGEMATYDAFALATSIGLRTPNMTLKVGPL 65 + L +W D + VA A G+A W E DA + T + +T + + Sbjct 5 INLGYWGAGMDADNLAVAQEADRLGYAVCWAAEAYGSDAATVLTWVAAQTHRIDVGSAIF 64 Query 66 AVGVRGPVGLALGVSSVASLTGCRVDLALGASSPAIVAGWHGRPWAHHVPVMRETIECLR 125 + R P A+ +++ SL+G R L LG S P + GW+G + + RE +E +R Sbjct 65 QIPARQPAMTAMTAATLDSLSGGRFRLGLGVSGPQVSEGWYGVKFDKPLARTREYVEIIR 124 Query 126 SIFTGARVEYSGRHVN-------SRGFRLRGAAPDTRIAL--GAFGPGMIRLAAQHADEV 176 T R+ Y G H + +L RI L A GP + + AD Sbjct 125 KAMTRERLSYEGEHWTLPLPGGPGKPIKLTVHPERERIPLYIAAIGPKNLEQTGEIADGA 184 Query 177 VLNLASPFRVGRVRA-AIDSAAAAAGRAAPRLTVC--VPVAVNPGAAAHSQLAAQL---- 229 +L S + I + AG+ +C VP+AV S LA Sbjct 185 LLIFPSADHLEDTAVRHIRAGREKAGKTLDGFDICPTVPLAVGDDKDV-STLADTFRPYT 243 Query 230 AVYLAPPG------YGEMFSALGFD---GLVRSARSRATRRELAVAVPSELLDRVCALGS 280 A+Y+ G Y ++ +G++ ++ ++ A AVP EL+D+ LGS Sbjct 244 ALYVGGMGSRKQNFYNQLAQRMGYEREAAEIQDKYLTGDKQGAAAAVPHELIDKTTLLGS 303 Query 281 PDRVAARLRAYADAGADCVAVVPA 304 DR+A R++AYA AGA + + PA Sbjct 304 VDRIADRMKAYAAAGATTLTLAPA 327 >gi|4218561|emb|CAA09650.1| putative FMN-dependent monooxygenase [Streptomyces violaceoruber] Length=343 Score = 93.6 bits (231), Expect = 4e-17, Method: Compositional matrix adjust. Identities = 102/335 (31%), Positives = 147/335 (44%), Gaps = 30/335 (8%) Query 19 ATDVALAAADTGFAALWIGEMATYDAFALATSIGLRTPNMTLKVGPLAVGVRGPVGLALG 78 A ++A AA +G+AA E DA ++ + T + L G + + R P AL Sbjct 12 AGELARAAERSGYAAALAPEGYRSDAASVLGLVAGVTERIALISGVMQIPGRPPAMTALT 71 Query 79 VSSVASLTGCRVDLALGASSPAIVAGWHGRPWAHHVPVMRETIECLRSIFTGARVEYSGR 138 +++ SL+G R L LG S+P + GW+G P+A + RE ++ +R G V Y G Sbjct 72 AATLDSLSGGRFRLGLGVSNPDVSVGWYGVPFARPLERTREYVDIVRRALEGDPVTYQGT 131 Query 139 HVNSRGFRLRGAAP-----DTR-----IALGAFGPGMIRLAAQHADEVVLNLASPFRVGR 188 H F + G AP + R + L A GP +RLA + AD + SP V Sbjct 132 H-----FEVGGPAPLHLLTERRPGRLPVLLAAVGPRNLRLAGEIADGWLGVFTSPEAVAE 186 Query 189 VRAAIDSAAAAAGRAAPRLTVCVPVAVNPGAAAHSQLAAQLAVYLAPPG------YGEMF 242 A I + +P AV A + + VYL G Y M Sbjct 187 SVAEIRKGRGTDDLDGFEVLPSLPTAVADSAQDAADMLRGQYVYLMGIGDPDRNFYCAMA 246 Query 243 SALGFDGLVRSARSR---ATRRELAVAVPSELLDRVCALGSPDRVAARLRAYADAGADCV 299 ++G++ V + R R A+P +DR +G DR+A R+RAYADAG + Sbjct 247 RSMGYEAEVAAFLERLAAGDRTGAGAALPLGFIDRTALIGPVDRIADRMRAYADAGVTTL 306 Query 300 AV-VPATAEDPGGRVAL-----RALRPGGLYGTAG 328 V V A A GR+A+ RAL G TAG Sbjct 307 GVMVSAAATGLEGRLAIVEAAARALERSGTATTAG 341 >gi|119475720|ref|ZP_01616073.1| hypothetical protein GP2143_17911 [marine gamma proteobacterium HTCC2143] gi|119451923|gb|EAW33156.1| hypothetical protein GP2143_17911 [marine gamma proteobacterium HTCC2143] Length=332 Score = 92.8 bits (229), Expect = 7e-17, Method: Compositional matrix adjust. Identities = 67/291 (24%), Positives = 125/291 (43%), Gaps = 8/291 (2%) Query 26 AADTGFAALWIGEMATYDAFALATSIGLRTPNMTLKVGPLAVGVRGPVGLALGVSSVASL 85 A D GF+ W + D+ +I T N+ + + V R P LA + + + Sbjct 27 AEDNGFSDAWFSDSGAPDSLTQVAAIAHHTTNLRIGIAVTPVYTRSPSVLAASANVIGQV 86 Query 86 TGCRVDLALGASSPAIVAGWHGRPWAHHVPVMRETIECLRSIFTGARVEYSGRHVNSRGF 145 R + LG+SS I+ ++G P + ++ET + ++ + G + + G V+S G+ Sbjct 87 LPGRFVMGLGSSSQTIMGKFNGIPLEKPLTRVKETAQLVKIMLAGEKTSFDGETVSSNGY 146 Query 146 RLRGAAPDTRIALGAFGPGMIRLAAQHADEVVLNLASPFRVGRVRAAIDSAAAAAGRAAP 205 R + L A MI +AA+ D V+ NL + ++ + AA AG+ Sbjct 147 RQAPMENPPPVYLAALRENMIEMAAEVGDGVIFNLWPKGALPKMMEHVAIGAARAGKKVE 206 Query 206 RLTVC---VPVAVNPGAAAHSQLAAQLAVYLAPPGYGEMFSALGFD---GLVRSARSRAT 259 + + + + + A A A Y A P Y + + G+ + + Sbjct 207 DVEIVNRAMVLCTDDKAYGRKLFRAAFAPYFATPVYNKFLAWAGYSDAANTINEGWAAKD 266 Query 260 RRELAVAVPSELLDRVCALGSPDRVAARLRAYADAGADCVAVVP--ATAED 308 R + A+ +L+D + +G+ + + R+R+ AD G + P ATA+D Sbjct 267 REKTGNALTDDLIDEIAIIGTREEIQQRIRSDADGGVHTHIIAPLAATADD 317 >gi|290954923|ref|YP_003486105.1| oxidoreductase [Streptomyces scabiei 87.22] gi|260644449|emb|CBG67534.1| putative oxidoreductase [Streptomyces scabiei 87.22] Length=384 Score = 92.8 bits (229), Expect = 7e-17, Method: Compositional matrix adjust. Identities = 90/335 (27%), Positives = 143/335 (43%), Gaps = 21/335 (6%) Query 6 VALPFWLDRPDHEATDVALAAADTGFAALWIGEMATYDAFALATSIGLRTPNMTLKVGPL 65 + L +W+ D +A A D G++A+W+ E DA + + I RT + + L Sbjct 10 LNLGYWVGGNDASNLSLASLAEDLGYSAVWVSEAYGSDAVTVMSWIAARTTRIDVGSAVL 69 Query 66 AVGVRGPVGLALGVSSVASLTGCRVDLALGASSPAIVAGWHGRPWAHHVPVMRETIECLR 125 + R P A+ +++ +L+G R+ L LG S P + GWHG +A + RE + +R Sbjct 70 QIPARSPATTAMTATTLDTLSGGRLRLGLGVSGPQVSEGWHGVRFASPLGRTREYVSLVR 129 Query 126 SIFTGARVEYSGRHVN-------SRGFRLRGAAPDTRIA--LGAFGPGMIRLAAQHADEV 176 + ++GRH + L P RI L A GP + L + AD Sbjct 130 RALRREPLAHAGRHFTLPLPDGPGKALTLTIRPPRERIPVYLAALGPKNLELTGEIADGW 189 Query 177 VLNLASPFRVGRVRAAIDSAAAAAGRAAPRLTVC--VPVAVNPG-AAAHSQLAAQLAVYL 233 + SP R + + A AGR + VP+ P + ++ A+YL Sbjct 190 LPVFFSPAHAARQLVPLKAGLAKAGRTLAGFDIAPGVPLVTGPDWRSCARRVRGYAALYL 249 Query 234 APPG------YGEMFSALGFDGLVRSARSRATRREL---AVAVPSELLDRVCALGSPDRV 284 G Y + +GF R+ + R + AVP LD LG +R+ Sbjct 250 GGMGGREDNHYTRLAERMGFGEGARAVQERFLAGDYPGAMAAVPLAFLDATSLLGPRERI 309 Query 285 AARLRAYADAGADCVAVVPATAEDPGGRVALRALR 319 A R+ A+A+AGA + ++P PG A ALR Sbjct 310 AERMTAFAEAGATTLNLMPVGPGLPGPDRAAGALR 344 >gi|312197446|ref|YP_004017507.1| F420-dependent oxidoreductase [Frankia sp. EuI1c] gi|311228782|gb|ADP81637.1| putative F420-dependent oxidoreductase [Frankia sp. EuI1c] Length=346 Score = 92.8 bits (229), Expect = 7e-17, Method: Compositional matrix adjust. Identities = 89/326 (28%), Positives = 140/326 (43%), Gaps = 31/326 (9%) Query 18 EATDVALAAADTGFAALWIGEMATYDAFALATSIGLRTPNMTLKVGPLAVGVRGPVGLAL 77 EA + G +++ E ++DA + + RT + L G L + R P A+ Sbjct 15 EAVEELADYEKAGLDIVFVAEAYSFDAVSQLGFLAARTARIELAAGILPIYTRTPTLTAM 74 Query 78 GVSSVASLTGCRVDLALGASSPAIVAGWHGRPWAHHVPVMRETIECLRSIFTGARVEYSG 137 + + ++G R L LGAS P ++ G+HG P+ + RE I+ R+++ R+EY G Sbjct 75 TAAGLDYVSGGRFTLGLGASGPQVIEGFHGVPYDAPLGRTREIIDICRAVWRRDRLEYQG 134 Query 138 RHVN-----------SRGFRLRGAAPDTRIA--LGAFGPGMIRLAAQHADEVVLNLASPF 184 +H + +L T I + A GP + LAA+ A+ P Sbjct 135 KHYTLPLPPEQGTGLGKPLKLINHPVRTHIPIFIAAIGPKNVELAAEKAEGWQPFFFHPG 194 Query 185 RVGRVRAAIDSAAAAAGRAAPRL-----TVCVPVAVNPGAAAHSQLA-AQLAVYLAPPG- 237 R G V A S AA + P L V P+A+ A + L A+Y+ G Sbjct 195 RAGDVWGA--SLAAGKAKRDPELGDLDVVVQAPLAIGDDAESWLDLMRPMFALYIGGMGA 252 Query 238 -----YGEMFSALGFD---GLVRSARSRATRRELAVAVPSELLDRVCALGSPDRVAARLR 289 Y + G++ L++ ++E AVP++LL +GS V +L Sbjct 253 KGKNFYNSLAQRYGYEKEAALIQDLYLDGKKKEAEAAVPADLLRATAMVGSEGEVREKLA 312 Query 290 AYADAGADCVAVVPATAEDPGGRVAL 315 YA+AGA + V P A D RVAL Sbjct 313 EYAEAGATTLNVTP-LAPDHRSRVAL 337 Lambda K H 0.322 0.136 0.410 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 599018624392 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40