BLASTP 2.2.25+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.



Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
           15,229,318 sequences; 5,219,829,388 total letters



Query= Rv3120

Length=200
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

gi|15610257|ref|NP_217636.1|  hypothetical protein Rv3120 [Mycoba...   399    9e-110
gi|340628306|ref|YP_004746758.1|  putative methyltransferase [Myc...   199    2e-49 
gi|167966723|ref|ZP_02549000.1|  hypothetical methyltransferase [...   199    2e-49 
gi|15842914|ref|NP_337951.1|  hypothetical protein MT3423 [Mycoba...   199    3e-49 
gi|257056858|ref|YP_003134690.1|  methyltransferase family protei...   105    3e-21 
gi|333921101|ref|YP_004494682.1|  methyltransferase [Amycolicicoc...  89.7    2e-16 
gi|336255061|ref|YP_004598168.1|  type 11 methyltransferase [Halo...  74.3    1e-11 
gi|225849486|ref|YP_002729651.1|  tellurite resistance protein Te...  63.5    2e-08 
gi|315505478|ref|YP_004084365.1|  type 12 methyltransferase [Micr...  62.8    2e-08 
gi|163782520|ref|ZP_02177517.1|  Tellurite resistance protein Teh...  62.8    3e-08 
gi|317506538|ref|ZP_07964335.1|  methyltransferase domain-contain...  61.2    7e-08 
gi|302868125|ref|YP_003836762.1|  thiopurine S-methyltransferase ...  60.8    1e-07 
gi|77917643|ref|YP_355458.1|  tellurite resistance protein [Pelob...  60.8    1e-07 
gi|182413260|ref|YP_001818326.1|  type 11 methyltransferase [Opit...  60.1    2e-07 
gi|258404394|ref|YP_003197136.1|  Methyltransferase type 12 [Desu...  59.3    3e-07 
gi|302524893|ref|ZP_07277235.1|  thioredoxin-disulfide reductase ...  58.9    4e-07 
gi|118470561|ref|YP_888580.1|  methyltransferase [Mycobacterium s...  58.9    4e-07 
gi|335040506|ref|ZP_08533633.1|  Methyltransferase type 11 [Calda...  58.2    7e-07 
gi|256397792|ref|YP_003119356.1|  methyltransferase type 12 [Cate...  58.2    7e-07 
gi|222479984|ref|YP_002566221.1|  methyltransferase type 11 [Halo...  58.2    7e-07 
gi|300710301|ref|YP_003736115.1|  pyridine nucleotide-disulfide o...  57.8    8e-07 
gi|296159000|ref|ZP_06841828.1|  Methyltransferase type 11 [Burkh...  57.8    9e-07 
gi|239989823|ref|ZP_04710487.1|  putative methyltransferase [Stre...  57.8    9e-07 
gi|114319823|ref|YP_741506.1|  type 12 methyltransferase [Alkalil...  57.4    1e-06 
gi|94310012|ref|YP_583222.1|  hypothetical protein Rmet_1067 [Cup...  56.6    2e-06 
gi|302548913|ref|ZP_07301255.1|  methyltransferase type 11 [Strep...  56.2    3e-06 
gi|288817454|ref|YP_003431801.1|  tellurite resistance protein [H...  55.8    4e-06 
gi|322418324|ref|YP_004197547.1|  type 12 methyltransferase [Geob...  55.5    4e-06 
gi|297560673|ref|YP_003679647.1|  hypothetical protein Ndas_1712 ...  55.1    5e-06 
gi|257054281|ref|YP_003132113.1|  methyltransferase family protei...  55.1    5e-06 
gi|158520928|ref|YP_001528798.1|  tellurite resistance protein Te...  54.7    7e-06 
gi|119475263|ref|ZP_01615616.1|  hypothetical protein GP2143_1562...  54.3    1e-05 
gi|326777466|ref|ZP_08236731.1|  Methyltransferase type 11 [Strep...  54.3    1e-05 
gi|319956879|ref|YP_004168142.1|  methyltransferase type 11 [Nitr...  54.3    1e-05 
gi|182436871|ref|YP_001824590.1|  putative methyltransferase [Str...  54.3    1e-05 
gi|197117283|ref|YP_002137710.1|  SAM-dependent methyltransferase...  53.9    1e-05 
gi|253701962|ref|YP_003023151.1|  methyltransferase type 12 [Geob...  53.5    2e-05 
gi|198284892|ref|YP_002221213.1|  type 12 methyltransferase [Acid...  53.5    2e-05 
gi|326316171|ref|YP_004233843.1|  type 11 methyltransferase [Acid...  53.1    2e-05 
gi|159038190|ref|YP_001537443.1|  type 11 methyltransferase [Sali...  52.8    3e-05 
gi|126731920|ref|ZP_01747724.1|  putative methyltransferase [Sagi...  52.8    3e-05 
gi|297153463|gb|ADI03175.1|  methyltransferase type 12 [Streptomy...  52.4    4e-05 
gi|218665549|ref|YP_002427572.1|  hypothetical protein AFE_3216 [...  52.4    4e-05 
gi|162450418|ref|YP_001612785.1|  methyltransferase [Sorangium ce...  52.4    4e-05 
gi|118470628|ref|YP_886876.1|  thiopurine S-methyltransferase (tp...  51.6    6e-05 
gi|95928815|ref|ZP_01311561.1|  Methyltransferase type 11 [Desulf...  51.6    7e-05 
gi|254564116|ref|YP_003071211.1|  S-adenosyl-L-methionine-depende...  51.2    9e-05 
gi|84686208|ref|ZP_01014103.1|  hypothetical protein 109945700025...  50.8    1e-04 
gi|240141606|ref|YP_002966086.1|  S-adenosyl-L-methionine-depende...  50.8    1e-04 
gi|315443843|ref|YP_004076722.1|  methylase involved in ubiquinon...  50.4    1e-04 


>gi|15610257|ref|NP_217636.1| hypothetical protein Rv3120 [Mycobacterium tuberculosis H37Rv]
 gi|15842691|ref|NP_337728.1| hypothetical protein MT3202 [Mycobacterium tuberculosis CDC1551]
 gi|148662974|ref|YP_001284497.1| hypothetical protein MRA_3152 [Mycobacterium tuberculosis H37Ra]
 71 more sequence titles
 Length=200

 Score =  399 bits (1026),  Expect = 9e-110, Method: Compositional matrix adjust.
 Identities = 200/200 (100%), Positives = 200/200 (100%), Gaps = 0/200 (0%)

Query  1    MSPSPSALLADHPDRIRWNAKYECADPTEAVFAPISWLGDVLQFGVPEGPVLELACGRSG  60
            MSPSPSALLADHPDRIRWNAKYECADPTEAVFAPISWLGDVLQFGVPEGPVLELACGRSG
Sbjct  1    MSPSPSALLADHPDRIRWNAKYECADPTEAVFAPISWLGDVLQFGVPEGPVLELACGRSG  60

Query  61   TALGLAAAGRCVTAIDVSDTALVQLELEATRRELADRLTLVHADLCSWQSGDGRFALVLC  120
            TALGLAAAGRCVTAIDVSDTALVQLELEATRRELADRLTLVHADLCSWQSGDGRFALVLC
Sbjct  61   TALGLAAAGRCVTAIDVSDTALVQLELEATRRELADRLTLVHADLCSWQSGDGRFALVLC  120

Query  121  RLFWHPPTFRQACEAVAPGGVVAWEAWRRPIDVARDTRRAEWCLKPGQPESELPAGFTVI  180
            RLFWHPPTFRQACEAVAPGGVVAWEAWRRPIDVARDTRRAEWCLKPGQPESELPAGFTVI
Sbjct  121  RLFWHPPTFRQACEAVAPGGVVAWEAWRRPIDVARDTRRAEWCLKPGQPESELPAGFTVI  180

Query  181  RVVDTDGSEPSRRIIAQRSL  200
            RVVDTDGSEPSRRIIAQRSL
Sbjct  181  RVVDTDGSEPSRRIIAQRSL  200


>gi|340628306|ref|YP_004746758.1| putative methyltransferase [Mycobacterium canettii CIPT 140010059]
 gi|340006496|emb|CCC45679.1| putative methyltransferase [Mycobacterium canettii CIPT 140010059]
Length=204

 Score =  199 bits (506),  Expect = 2e-49, Method: Compositional matrix adjust.
 Identities = 115/200 (58%), Positives = 135/200 (68%), Gaps = 2/200 (1%)

Query  1    MSPSPSALLADHPDRIRWNAKYECADPTEAVFAPISWLGDVLQFGVPEGPVLELACGRSG  60
            MS      L +HP+R+ WNA+YE A    A FAP+ WL DVL+ GVP+GPVLELA GRSG
Sbjct  1    MSVQTDPALREHPNRVDWNARYERAGSAHAPFAPVPWLADVLRAGVPDGPVLELASGRSG  60

Query  61   TALGLAAAGRCVTAIDVSDTALVQLELEATRRELADRLTLVHADLCSWQSGDGRFALVLC  120
            TAL LAA GR VTAIDVSD AL+QLE EA RR +ADRL LV ADL  W+ G+ RFALVL 
Sbjct  61   TALALAAHGRQVTAIDVSDVALLQLESEAVRRGVADRLNLVQADLGCWEPGETRFALVLS  120

Query  121  RLFWHPPTFRQACEAVAPGGVVAWEAWRRPIDVARDTRRAEWCLKPGQPESELPAGFTVI  180
            RLFW    F +ACEAV PGGV+AWE+       A  T  A+  +KPG+P   LPA FTV+
Sbjct  121  RLFWDAAIFHRACEAVMPGGVLAWESLALSGAEA-GTASAKRRVKPGEPACLLPADFTVV  179

Query  181  RVVDTD-GSEPSRRIIAQRS  199
                    S PSR +IA+RS
Sbjct  180  HEGQGSCDSAPSRIMIARRS  199


>gi|167966723|ref|ZP_02549000.1| hypothetical methyltransferase [Mycobacterium tuberculosis H37Ra]
 gi|253800367|ref|YP_003033368.1| methyltransferase [Mycobacterium tuberculosis KZN 1435]
 gi|254365943|ref|ZP_04981988.1| hypothetical methyltransferase [Mycobacterium tuberculosis str. 
Haarlem]
 gi|254552426|ref|ZP_05142873.1| methyltransferase [Mycobacterium tuberculosis '98-R604 INH-RIF-EM']
 gi|134151456|gb|EBA43501.1| hypothetical methyltransferase [Mycobacterium tuberculosis str. 
Haarlem]
 gi|253321870|gb|ACT26473.1| methyltransferase [Mycobacterium tuberculosis KZN 1435]
 gi|339296149|gb|AEJ48260.1| hypothetical methyltransferase [Mycobacterium tuberculosis CCDC5079]
 gi|339299758|gb|AEJ51868.1| hypothetical methyltransferase [Mycobacterium tuberculosis CCDC5180]
Length=210

 Score =  199 bits (506),  Expect = 2e-49, Method: Compositional matrix adjust.
 Identities = 114/200 (57%), Positives = 136/200 (68%), Gaps = 2/200 (1%)

Query  1    MSPSPSALLADHPDRIRWNAKYECADPTEAVFAPISWLGDVLQFGVPEGPVLELACGRSG  60
            MS      L +HP+R+ WNA+YE A    A FAP+ WL DVL+ GVP+GPVLELA GRSG
Sbjct  7    MSVQTDPALREHPNRVDWNARYERAGSAHAPFAPVPWLADVLRAGVPDGPVLELASGRSG  66

Query  61   TALGLAAAGRCVTAIDVSDTALVQLELEATRRELADRLTLVHADLCSWQSGDGRFALVLC  120
            TAL LAA GR VTAIDVSD AL+QL+ EA RR +ADRL LV ADL  W+ G+ RFALVL 
Sbjct  67   TALALAAHGRQVTAIDVSDVALLQLDSEAVRRGVADRLNLVQADLGCWEPGETRFALVLS  126

Query  121  RLFWHPPTFRQACEAVAPGGVVAWEAWRRPIDVARDTRRAEWCLKPGQPESELPAGFTVI  180
            RLFW    F +ACEAV PGGV+AWE+       A  T  A+  +KPG+P   LPA FTV+
Sbjct  127  RLFWDAAIFHRACEAVMPGGVLAWESLALSGAEA-GTASAKRRVKPGEPACLLPADFTVV  185

Query  181  RVVDTD-GSEPSRRIIAQRS  199
                 +  S PSR +IA+RS
Sbjct  186  HEGQGNCDSAPSRIMIARRS  205


>gi|15842914|ref|NP_337951.1| hypothetical protein MT3423 [Mycobacterium tuberculosis CDC1551]
 gi|31794503|ref|NP_856996.1| methyltransferase [Mycobacterium bovis AF2122/97]
 gi|57117089|ref|YP_177958.1| methyltransferase [Mycobacterium tuberculosis H37Rv]
 68 more sequence titles
 Length=204

 Score =  199 bits (505),  Expect = 3e-49, Method: Compositional matrix adjust.
 Identities = 114/200 (57%), Positives = 136/200 (68%), Gaps = 2/200 (1%)

Query  1    MSPSPSALLADHPDRIRWNAKYECADPTEAVFAPISWLGDVLQFGVPEGPVLELACGRSG  60
            MS      L +HP+R+ WNA+YE A    A FAP+ WL DVL+ GVP+GPVLELA GRSG
Sbjct  1    MSVQTDPALREHPNRVDWNARYERAGSAHAPFAPVPWLADVLRAGVPDGPVLELASGRSG  60

Query  61   TALGLAAAGRCVTAIDVSDTALVQLELEATRRELADRLTLVHADLCSWQSGDGRFALVLC  120
            TAL LAA GR VTAIDVSD AL+QL+ EA RR +ADRL LV ADL  W+ G+ RFALVL 
Sbjct  61   TALALAAHGRQVTAIDVSDVALLQLDSEAVRRGVADRLNLVQADLGCWEPGETRFALVLS  120

Query  121  RLFWHPPTFRQACEAVAPGGVVAWEAWRRPIDVARDTRRAEWCLKPGQPESELPAGFTVI  180
            RLFW    F +ACEAV PGGV+AWE+       A  T  A+  +KPG+P   LPA FTV+
Sbjct  121  RLFWDAAIFHRACEAVMPGGVLAWESLALSGAEA-GTASAKRRVKPGEPACLLPADFTVV  179

Query  181  RVVDTD-GSEPSRRIIAQRS  199
                 +  S PSR +IA+RS
Sbjct  180  HEGQGNCDSAPSRIMIARRS  199


>gi|257056858|ref|YP_003134690.1| methyltransferase family protein [Saccharomonospora viridis DSM 
43017]
 gi|256586730|gb|ACU97863.1| methyltransferase family protein [Saccharomonospora viridis DSM 
43017]
Length=256

 Score =  105 bits (262),  Expect = 3e-21, Method: Compositional matrix adjust.
 Identities = 68/133 (52%), Positives = 84/133 (64%), Gaps = 3/133 (2%)

Query  14   DRIRWNAKYECADPTEAVFAPISWLGDVLQFGVPEGPVLELACGRSGTALGLAAAGRCVT  73
            DR+RWNA+Y  + P    F P   + +    G+ +GPVLELACGRSG+AL LA AGR V 
Sbjct  17   DRLRWNARYRRSAPD---FTPHPLVAEAFAAGMVDGPVLELACGRSGSALALAEAGRRVV  73

Query  74   AIDVSDTALVQLELEATRRELADRLTLVHADLCSWQSGDGRFALVLCRLFWHPPTFRQAC  133
            A+DVSD AL QL  EA RR +A R+  V ADL ++    G FA VL   FW    F  A 
Sbjct  74   AVDVSDVALQQLATEAKRRGVAARVACVQADLETFVPPRGMFAFVLATRFWDAAVFDAAR  133

Query  134  EAVAPGGVVAWEA  146
            EAV+PGG++ WEA
Sbjct  134  EAVSPGGLLGWEA  146


>gi|333921101|ref|YP_004494682.1| methyltransferase [Amycolicicoccus subflavus DQS3-9A1]
 gi|333483322|gb|AEF41882.1| Methyltransferase [Amycolicicoccus subflavus DQS3-9A1]
Length=184

 Score = 89.7 bits (221),  Expect = 2e-16, Method: Compositional matrix adjust.
 Identities = 64/168 (39%), Positives = 85/168 (51%), Gaps = 9/168 (5%)

Query  13   PDRIRWNAKYECADPTEAVFAPISWLGDVLQFGVPEGPVLELACGRSGTALGLAAAGRCV  72
            PD+ RWN ++    P+  V   +S L  +     P+GPVLE+ACG SG+AL  A  GR V
Sbjct  5    PDQERWNRRHSLQAPSFRVSPLVSQLRAI---NPPDGPVLEIACGTSGSALEFAREGRRV  61

Query  73   TAIDVSDTALVQLELEATRRELADRLTLVHADLCSWQSGDGRFALVLCRLFWHPPTFRQA  132
             A+DVSD AL  L  EA R  + D +  V AD  +       FA+VL   FW    F  A
Sbjct  62   VAVDVSDVALNHLAAEAARLGVTDFIEFVEADAAAHSFTPRHFAIVLATFFWDAAAFEHA  121

Query  133  CEAVAPGGVVAWEAWRRPIDVARDTRRAEWCLKPGQPESELPAGFTVI  180
            C AVAP G + W+A   P+  +R      W +  G   + LP  F  +
Sbjct  122  CNAVAPDGALGWQALASPVAGSR------WRVPHGHLSAALPGDFGAV  163


>gi|336255061|ref|YP_004598168.1| type 11 methyltransferase [Halopiger xanaduensis SH-6]
 gi|335339050|gb|AEH38289.1| Methyltransferase type 11 [Halopiger xanaduensis SH-6]
Length=213

 Score = 74.3 bits (181),  Expect = 1e-11, Method: Compositional matrix adjust.
 Identities = 54/150 (36%), Positives = 74/150 (50%), Gaps = 5/150 (3%)

Query  8    LLADHPDRIRWNAKYECADPTEAVFAPISWLGDVLQFGVPEGPVLELACGRSGTALGLAA  67
            +  D  DR RWN KY  AD  E    PI  L   L+  +PEG  L++A G    A+ LAA
Sbjct  1    MTDDRDDRERWNEKYNDAD-FELPGDPIPVLERRLET-LPEGRALDVATGTGRNAVFLAA  58

Query  68   AGRCVTAIDVSDTALVQLELEATRRELADRLTLVHADLCSWQSGDGRFALVLCRLFWHPP  127
             G  V A+DVSD AL + +  A  R + D +  + ADL  ++   G + ++    F    
Sbjct  59   NGYDVDAVDVSDEALERAQQRADERGVDDSVDWIRADLAEYEFESGAYDVITIGFFAALE  118

Query  128  TFRQACEAVAPGGVVAWEAWRR---PIDVA  154
                  EA+AP GV+ +E   R   PIDV 
Sbjct  119  HLPDIKEALAPSGVLVYEHHLRSSDPIDVG  148


>gi|225849486|ref|YP_002729651.1| tellurite resistance protein TehB [Sulfurihydrogenibium azorense 
Az-Fu1]
 gi|225644321|gb|ACN99371.1| tellurite resistance protein TehB [Sulfurihydrogenibium azorense 
Az-Fu1]
Length=184

 Score = 63.5 bits (153),  Expect = 2e-08, Method: Compositional matrix adjust.
 Identities = 43/135 (32%), Positives = 65/135 (49%), Gaps = 11/135 (8%)

Query  14   DRIRWNAKY-ECADPTEAVFAPISWLGDVLQFGVPEGPVLELACGRSGTALGLAAAGRCV  72
            DR RWN KY E   P E    P + L D +     +G  L++A G    AL LA  G  V
Sbjct  5    DRERWNKKYLEGFLPKEE---PSTILKDFIHLA-NKGKALDIAAGLGRNALFLAQNGFTV  60

Query  73   TAIDVSDTALVQLELEATRRELADRLTLVHADLCSWQSGDGRFALVLCRLFWHPPTFRQA  132
             A+D+SD A+ +L      + L   +  +HADL  ++  +  + L++   F     F   
Sbjct  61   DAVDISDVAIEKL------KNLHPNINPIHADLKEYRPPENTYDLIVNVNFLERSLFPYI  114

Query  133  CEAVAPGGVVAWEAW  147
             EA+  GGV+ +E +
Sbjct  115  KEALKEGGVLIFETF  129


>gi|315505478|ref|YP_004084365.1| type 12 methyltransferase [Micromonospora sp. L5]
 gi|315412097|gb|ADU10214.1| Methyltransferase type 12 [Micromonospora sp. L5]
Length=216

 Score = 62.8 bits (151),  Expect = 2e-08, Method: Compositional matrix adjust.
 Identities = 43/101 (43%), Positives = 56/101 (56%), Gaps = 7/101 (6%)

Query  46   VPEGPVLELACGRSGTALGLAAAGRCVTAIDVSDTALVQLELEATRRELADRLTLVHADL  105
            +P G VL+L  G  G A+ LA+ G  VTA+D+S  AL +L +EA R  +ADR+T V  DL
Sbjct  45   LPPGTVLDLGSGEGGDAVWLASKGWRVTAVDISSVALDRLTVEAERAGVADRITTVRHDL  104

Query  106  CSWQSGDGRFALVLCRLFWHPPTFRQ------ACEAVAPGG  140
                   GR+ LV  + F  P    +      A EAVAPGG
Sbjct  105  TQGFP-PGRYDLVSAQFFQSPLVLPREKVLPPAAEAVAPGG  144


>gi|163782520|ref|ZP_02177517.1| Tellurite resistance protein TehB [Hydrogenivirga sp. 128-5-R1-1]
 gi|159882093|gb|EDP75600.1| Tellurite resistance protein TehB [Hydrogenivirga sp. 128-5-R1-1]
Length=166

 Score = 62.8 bits (151),  Expect = 3e-08, Method: Compositional matrix adjust.
 Identities = 37/127 (30%), Positives = 62/127 (49%), Gaps = 2/127 (1%)

Query  47   PEGPVLELACGRSGTALGLAAAGRCVTAIDVSDTALVQLELEATRRELADRLTLVHADLC  106
            P G  L++ACG   T++ LA  G  V A DVSD A+ +  L+A R  ++ +   + AD  
Sbjct  20   PYGRALDIACGTGETSIYLAKKGFSVEAFDVSDVAIRKARLKAKREGVSVKFKPLDADRF  79

Query  107  SWQSGDGRFALVLCRLFWHPPTFRQACEAVAPGGVVAWEAWRRPIDVARDTRRAEWCLKP  166
            S+  G  R+ L+L   F +  TF +   ++  GGV+ +E +         +    + L+ 
Sbjct  80   SF--GVSRYNLILNFYFLNRNTFPKIKRSLKSGGVLIFETYNEDHSSVNPSFNPSYLLRK  137

Query  167  GQPESEL  173
            G+   E 
Sbjct  138  GELIEEF  144


>gi|317506538|ref|ZP_07964335.1| methyltransferase domain-containing protein [Segniliparus rugosus 
ATCC BAA-974]
 gi|316255177|gb|EFV14450.1| methyltransferase domain-containing protein [Segniliparus rugosus 
ATCC BAA-974]
Length=225

 Score = 61.2 bits (147),  Expect = 7e-08, Method: Compositional matrix adjust.
 Identities = 43/133 (33%), Positives = 62/133 (47%), Gaps = 14/133 (10%)

Query  14   DRIRWNAKYECADPTEAVFAPISWLGDVLQFGVPEGPVLELACGRSGTALGLAAAGRCVT  73
            DRI     +   +P   + A       +++ G   G VL+  CG + T+L LAA G  V 
Sbjct  12   DRISGEPPWNIGEPQPEINA-------LIEAGEFHGTVLDAGCGHAETSLKLAALGYTVV  64

Query  74   AIDVSDTALVQLELEATRRELADRLTLVHADLCSWQSGDGRFALVLCRLFWH--PPTFRQ  131
             +D+S TA+      A  R L+DR T   AD+ S+   DGRF  ++    +H  P  FR+
Sbjct  65   GLDLSPTAIAAATKSAEERGLSDRATYEVADISSFTGYDGRFDTIVDSTLFHSMPVEFRE  124

Query  132  A-----CEAVAPG  139
                    A APG
Sbjct  125  GYLSSILRAAAPG  137


>gi|302868125|ref|YP_003836762.1| thiopurine S-methyltransferase [Micromonospora aurantiaca ATCC 
27029]
 gi|302570984|gb|ADL47186.1| thiopurine S-methyltransferase [Micromonospora aurantiaca ATCC 
27029]
Length=216

 Score = 60.8 bits (146),  Expect = 1e-07, Method: Compositional matrix adjust.
 Identities = 42/101 (42%), Positives = 55/101 (55%), Gaps = 7/101 (6%)

Query  46   VPEGPVLELACGRSGTALGLAAAGRCVTAIDVSDTALVQLELEATRRELADRLTLVHADL  105
            +P G VL+L  G  G A+ LA+ G  V A+D+S  AL +L +EA R  +ADR+T V  DL
Sbjct  45   LPPGTVLDLGSGEGGDAVWLASKGWRVAAVDISSVALDRLTVEAERAGVADRITTVRHDL  104

Query  106  CSWQSGDGRFALVLCRLFWHPPTFRQ------ACEAVAPGG  140
                   GR+ LV  + F  P    +      A EAVAPGG
Sbjct  105  TQGFP-PGRYDLVSAQFFQSPLVLPREKVLPPAAEAVAPGG  144


>gi|77917643|ref|YP_355458.1| tellurite resistance protein [Pelobacter carbinolicus DSM 2380]
 gi|77543726|gb|ABA87288.1| tellurite resistance protein [Pelobacter carbinolicus DSM 2380]
Length=194

 Score = 60.8 bits (146),  Expect = 1e-07, Method: Compositional matrix adjust.
 Identities = 55/168 (33%), Positives = 76/168 (46%), Gaps = 14/168 (8%)

Query  18   WNAKYECADPTEAVFAPISWLGDVLQFGVPEGPVLELACGRSGTALGLAAAGRCVTAIDV  77
            WN  ++    T+    P  WL  VL    P G VL+LACGR   AL LA  G  VTA+D 
Sbjct  8    WNKIWQERANTD--LHPDPWLRKVLPLLPPAGRVLDLACGRGRNALFLAEGGYAVTAVDA  65

Query  78   SDTALVQLELEATRRELADRLTLVHADLCSWQSGDGR-----FALVLCRLFWHPPTFRQA  132
            S  AL QL  EA RR L  R+  +  DL +    D R     F +V+   +       + 
Sbjct  66   SGEALGQLASEAQRRGL--RIDRLQQDLET----DPRLVLDPFDVVIQFFYLQRSLIPEM  119

Query  133  CEAVAPGGVVAWEAWRRPIDVARDTRRAEWCLKPGQPESELPAGFTVI  180
               V PGG+     + R  +         + L PG+ ++ L AG+ V+
Sbjct  120  QRLVKPGGIAVMRTFSRAGNFPGGPGNPAFSLDPGELQA-LFAGWQVL  166


>gi|182413260|ref|YP_001818326.1| type 11 methyltransferase [Opitutus terrae PB90-1]
 gi|177840474|gb|ACB74726.1| Methyltransferase type 11 [Opitutus terrae PB90-1]
Length=200

 Score = 60.1 bits (144),  Expect = 2e-07, Method: Compositional matrix adjust.
 Identities = 46/135 (35%), Positives = 62/135 (46%), Gaps = 9/135 (6%)

Query  18   WNAKYECADPTEAVFAPISWLGDVLQFGVPEGPVLELACGRSGTALGLAAAGRCVTAIDV  77
            WNA+Y  AD      AP  +L D     +P GPVL L  G    A+ LA  G  VTA+D 
Sbjct  6    WNARYSAADYVYGT-APNGFLVDCAAH-IPSGPVLCLGEGEGRNAVFLAGRGHAVTAVDQ  63

Query  78   SDTALVQLELEATRRELADRLTLVHADLCSWQSGDGRFALVLCRLFWHPPTFR-----QA  132
            S+  L +    A  R ++  L  V  D+  +    G +A V+   F  PP  R     QA
Sbjct  64   SEVGLAKARRLAAERGVS--LATVVTDISDYAIAPGAWAAVVSIFFHLPPALRRRVHQQA  121

Query  133  CEAVAPGGVVAWEAW  147
               +  GGV+  EA+
Sbjct  122  AAGLQSGGVIILEAY  136


>gi|258404394|ref|YP_003197136.1| Methyltransferase type 12 [Desulfohalobium retbaense DSM 5692]
 gi|257796621|gb|ACV67558.1| Methyltransferase type 12 [Desulfohalobium retbaense DSM 5692]
Length=182

 Score = 59.3 bits (142),  Expect = 3e-07, Method: Compositional matrix adjust.
 Identities = 56/177 (32%), Positives = 80/177 (46%), Gaps = 25/177 (14%)

Query  14   DRIRWNAKYECADPTEAVFAPISWLGDVLQFGVPEGP---VLELACGRSGTALGLAAAGR  70
            DR RWN +Y    P E V A       +L   VP+G     L+LA G    A  LA  G 
Sbjct  4    DRTRWNDRYRNNPPPERVCA-------LLPDHVPDGEGKTALDLAGGTGANAAFLADKGY  56

Query  71   CVTAIDVSDTALVQLELEATRRELADRLTLVHADLCSWQSGDGRFALVLCRLFWHPPTFR  130
             V ++D++D A+ +L+          R+  V ADL +++    RF LVL   F     F 
Sbjct  57   QVYSVDIADAAIQRLQERG-----HPRIHPVQADLDTYRPPAERFDLVLTVRFLDRRLFP  111

Query  131  QACEAVAPGGVVAWEAW----RRPIDVARDTRRAEWCLKPGQPESELPAGFTVIRVV  183
               EA+ PGGV+         RR  D  + T   +  L+P    +EL   F+ +R+V
Sbjct  112  YLAEALVPGGVLLIHTLLDDPRR--DCPQMTSNRDHLLRP----NELVRSFSNLRIV  162


>gi|302524893|ref|ZP_07277235.1| thioredoxin-disulfide reductase [Streptomyces sp. AA4]
 gi|302433788|gb|EFL05604.1| thioredoxin-disulfide reductase [Streptomyces sp. AA4]
Length=531

 Score = 58.9 bits (141),  Expect = 4e-07, Method: Compositional matrix adjust.
 Identities = 53/147 (37%), Positives = 67/147 (46%), Gaps = 24/147 (16%)

Query  10   ADHP--DRIRWNAKYECADPTEAVFAPISWLGDVLQFGVPE------GPVLELACGRSGT  61
            AD P  DR  W  +Y   D          W G      V E      G  L+  CG  G 
Sbjct  331  ADTPPFDRASWEERYRSRDEM--------WSGRPNDQLVTEARDLEPGHALDAGCGEGGD  382

Query  62   ALGLAAAGRCVTAIDVSDTALVQLELEATRRELADRLTLVHADLCSWQSGDGRFALVLCR  121
            AL LA  G  VTA+D S TA+ +   +A +  LADR+T V ADL  W   + +F LV   
Sbjct  383  ALWLAQQGWRVTAVDFSTTAIERGRAQAAKLGLADRITWVAADLAEWLP-ESKFDLVTTH  441

Query  122  LFWHPPT------FRQACEAVAPGGVV  142
             F H P+      F +  +AVAPGG +
Sbjct  442  -FLHVPSAARTAAFARLADAVAPGGTL  467


>gi|118470561|ref|YP_888580.1| methyltransferase [Mycobacterium smegmatis str. MC2 155]
 gi|118171848|gb|ABK72744.1| methyltransferase [Mycobacterium smegmatis str. MC2 155]
Length=518

 Score = 58.9 bits (141),  Expect = 4e-07, Method: Compositional matrix adjust.
 Identities = 43/102 (43%), Positives = 53/102 (52%), Gaps = 9/102 (8%)

Query  46   VPEGPVLELACGRSGTALGLAAAGRCVTAIDVSDTALVQLELEATRRELADRLTLVHADL  105
            +P G  L+L CG  G A+ LA  G  VTA+D+S TAL +   EA RR +ADR+T    DL
Sbjct  346  LPAGHALDLGCGEGGDAVWLAERGWRVTAVDISHTALSRAAAEAGRRGVADRITFERHDL  405

Query  106  CSWQSGDGRFALVLCRLFWH-------PPTFRQACEAVAPGG  140
             S    DG F LV  + F H       P     A  A+ PGG
Sbjct  406  -SESFPDGEFDLVSAQ-FLHSTVRLERPRILSTAARAIRPGG  445


>gi|335040506|ref|ZP_08533633.1| Methyltransferase type 11 [Caldalkalibacillus thermarum TA2.A1]
 gi|334179586|gb|EGL82224.1| Methyltransferase type 11 [Caldalkalibacillus thermarum TA2.A1]
Length=195

 Score = 58.2 bits (139),  Expect = 7e-07, Method: Compositional matrix adjust.
 Identities = 49/162 (31%), Positives = 75/162 (47%), Gaps = 9/162 (5%)

Query  14   DRIRWNAKYECADPTEAVFAP----ISWLGDVLQFGVP---EGPVLELACGRSGTALGLA  66
            DRI+WN KYE         +P    ++ L  VL+ G+    +G  L+LACG  G +L LA
Sbjct  5    DRIKWNHKYESKLAKTVQPSPPNKRLALLMPVLKNGLKSNCKGEALDLACGLGGNSLYLA  64

Query  67   AAGRCVTAIDVSDTALVQLELEATRRELADRLTLVHADLCSWQSGDGRFALVLCRLFWHP  126
              G  VTA+D+SD A+  L   A   +L     +V  DL   +    ++ LV+   +   
Sbjct  65   RQGFRVTALDISDVAINCLAKLAEEEQLPIDGRVV--DLEEIKLPPVQYDLVIKTYYLQR  122

Query  127  PTFRQACEAVAPGGVVAWEAWRRPIDVARDTRRAEWCLKPGQ  168
              F Q    + P G+V  E + +    A    R  + L+P +
Sbjct  123  DLFEQVKRTLKPSGLVFVETFLQTEHDANPHIRPAYKLQPQE  164


>gi|256397792|ref|YP_003119356.1| methyltransferase type 12 [Catenulispora acidiphila DSM 44928]
 gi|256364018|gb|ACU77515.1| Methyltransferase type 12 [Catenulispora acidiphila DSM 44928]
Length=217

 Score = 58.2 bits (139),  Expect = 7e-07, Method: Compositional matrix adjust.
 Identities = 50/134 (38%), Positives = 67/134 (50%), Gaps = 13/134 (9%)

Query  18   WNAKYECADPTEAVFAPISWLGDVL-QFGVPEGPVLELACGRSGTALGLAAAGRCVTAID  76
            W   Y   DP+     P   L D+L  F  P G  L+L CG  G A+ LA  G  VTA+D
Sbjct  13   WEKHYARFDPSWGT-KPNVVLKDLLATFAPPPGTALDLGCGHGGDAIWLATQGWDVTAVD  71

Query  77   VSDTALVQLELEATRRELADRLTLVHADLC-SWQSGDGRFALVLCRLFWHPP-------T  128
            VS TAL ++   A     A+R+  V  DL  ++ +GD  F LV C  ++H P        
Sbjct  72   VSQTALDRVAEGAWAVSAAERVHPVRHDLAQTFPAGD--FDLV-CATYFHTPIAIPRTEV  128

Query  129  FRQACEAVAPGGVV  142
             R+A  AVAP G++
Sbjct  129  LRKAARAVAPNGLL  142


>gi|222479984|ref|YP_002566221.1| methyltransferase type 11 [Halorubrum lacusprofundi ATCC 49239]
 gi|222452886|gb|ACM57151.1| Methyltransferase type 11 [Halorubrum lacusprofundi ATCC 49239]
Length=216

 Score = 58.2 bits (139),  Expect = 7e-07, Method: Compositional matrix adjust.
 Identities = 33/108 (31%), Positives = 51/108 (48%), Gaps = 0/108 (0%)

Query  46   VPEGPVLELACGRSGTALGLAAAGRCVTAIDVSDTALVQLELEATRRELADRLTLVHADL  105
            +P+G  L++A G    A+ LA AG  V A+D S   L  +   A  R++ADR+  + AD 
Sbjct  30   IPDGRALDVAAGTGRNAVYLAEAGYAVDALDASREGLAIVRERAAERDVADRVETIQADA  89

Query  106  CSWQSGDGRFALVLCRLFWHPPTFRQACEAVAPGGVVAWEAWRRPIDV  153
             ++   D  + L+    F     F    E++ PGG +  E   R  D 
Sbjct  90   STYGFPDETYELITMSFFHTLDRFADLIESLTPGGYLFVEGHLRSADA  137


>gi|300710301|ref|YP_003736115.1| pyridine nucleotide-disulfide oxidoreductase, class II [Halalkalicoccus 
jeotgali B3]
 gi|299123984|gb|ADJ14323.1| pyridine nucleotide-disulfide oxidoreductase, class II, putative 
[Halalkalicoccus jeotgali B3]
Length=183

 Score = 57.8 bits (138),  Expect = 8e-07, Method: Compositional matrix adjust.
 Identities = 38/132 (29%), Positives = 65/132 (50%), Gaps = 6/132 (4%)

Query  14   DRIRWNAKYECADPTEAVFAPI-SWLGDVLQFGVPEGPVLELACGRSGTALGLAAAGRCV  72
            +R RWN +Y   DP +     +  W+ D+     PEG  L++A G    A+ LA  G  V
Sbjct  4    ERTRWNERYRERDPPDDPSDLLREWVDDL-----PEGRALDVATGGGRNAICLAEHGYAV  58

Query  73   TAIDVSDTALVQLELEATRRELADRLTLVHADLCSWQSGDGRFALVLCRLFWHPPTFRQA  132
             AID S+  L      A+ R +++R+  V  D+ ++    G + +++   ++        
Sbjct  59   DAIDCSEEGLEIARDRASDRGVSERIGFVRDDVETYDFPAGTYDVIVVSRYYSLNVLPAL  118

Query  133  CEAVAPGGVVAW  144
             EA+APGGV+ +
Sbjct  119  KEALAPGGVLLY  130


>gi|296159000|ref|ZP_06841828.1| Methyltransferase type 11 [Burkholderia sp. Ch1-1]
 gi|295890875|gb|EFG70665.1| Methyltransferase type 11 [Burkholderia sp. Ch1-1]
Length=199

 Score = 57.8 bits (138),  Expect = 9e-07, Method: Compositional matrix adjust.
 Identities = 45/138 (33%), Positives = 62/138 (45%), Gaps = 10/138 (7%)

Query  34   PISWLGDVLQFGVPEGPVLELACGRSGTALGLAAAGRCVTAIDVSDTALVQLELEATRRE  93
            P  W+ D        GPVL++ACG    A   AA G  VTAID    AL  L  E     
Sbjct  14   PSPWVRDWAHLVAAGGPVLDVACGAGRHARFFAALGHPVTAIDRDAAALATLRGEPL---  70

Query  94   LADRLTLVHADL--CSWQ-SGDGRFALVLCRLFWHPPTFRQACEAVAPGGVVAWEAWRRP  150
                +T + ADL    W    + +FA V+   + H P F Q   A+APGGV+ +E + + 
Sbjct  71   ----VTPLEADLEGAGWPLPAEAKFAAVVVTNYLHRPLFAQLLHALAPGGVLVYETFAQG  126

Query  151  IDVARDTRRAEWCLKPGQ  168
             +         + L PG+
Sbjct  127  NERVGKPSNPAFLLAPGE  144


>gi|239989823|ref|ZP_04710487.1| putative methyltransferase [Streptomyces roseosporus NRRL 11379]
 gi|291446838|ref|ZP_06586228.1| methyltransferase [Streptomyces roseosporus NRRL 15998]
 gi|291349785|gb|EFE76689.1| methyltransferase [Streptomyces roseosporus NRRL 15998]
Length=227

 Score = 57.8 bits (138),  Expect = 9e-07, Method: Compositional matrix adjust.
 Identities = 50/137 (37%), Positives = 63/137 (46%), Gaps = 14/137 (10%)

Query  18   WNAKYECADPTEAVFAPISWLGDVLQFGVPE------GPVLELACGRSGTALGLAAAGRC  71
            W   Y   DP      P + L +V+     E      G  L+L CG  G AL LA+ G  
Sbjct  18   WENHYAGVDPQWGT-RPNAVLAEVVTALASEPGSGGGGRALDLGCGHGGDALWLASLGWD  76

Query  72   VTAIDVSDTALVQLELEATRRELADRLTLVHADLCSWQSGDGRFALVLCRLFWHP-----  126
            VTA+DVS TAL ++   A    L DR+  +  DL      DG F LV    F  P     
Sbjct  77   VTAVDVSATALERVAAGADAAGLTDRVHPIRHDLAR-SFPDGTFELVTASYFHTPVEIPR  135

Query  127  -PTFRQACEAVAPGGVV  142
                R+A EAVAPGG++
Sbjct  136  EQVLRRAAEAVAPGGLL  152


>gi|114319823|ref|YP_741506.1| type 12 methyltransferase [Alkalilimnicola ehrlichii MLHE-1]
 gi|114226217|gb|ABI56016.1| Methyltransferase type 12 [Alkalilimnicola ehrlichii MLHE-1]
Length=200

 Score = 57.4 bits (137),  Expect = 1e-06, Method: Compositional matrix adjust.
 Identities = 45/135 (34%), Positives = 62/135 (46%), Gaps = 6/135 (4%)

Query  15   RIRWNAKYECADPTEAVFAPISWLGDVLQFGVPEGPVLELACGRSGTALGLAAAGRCVTA  74
            R  W+ +Y  A+P  A     + L D L    P G  L+LACG    A+ LA AG    A
Sbjct  15   RQGWDQRYRQAEPGSAA----AVLADNLHLLPPRGRALDLACGLGSNAMLLAGAGLETEA  70

Query  75   IDVSDTALVQLELEATRRELADRLTLVHADLCSWQSGDGRFALVLCRLFWHPPTFRQACE  134
             D S  AL +L   A R+ LA  +T    D+         F +++   F H PT      
Sbjct  71   WDYSPVALERLMERARRQGLA--ITPRERDVEQHPPPAVSFDVIVVAHFLHRPTAPDLFR  128

Query  135  AVAPGGVVAWEAWRR  149
            A+ PGGV+ ++ W R
Sbjct  129  ALRPGGVLFYQTWSR  143


>gi|94310012|ref|YP_583222.1| hypothetical protein Rmet_1067 [Cupriavidus metallidurans CH34]
 gi|93353864|gb|ABF07953.1| conserved hypothetical protein [Cupriavidus metallidurans CH34]
Length=191

 Score = 56.6 bits (135),  Expect = 2e-06, Method: Compositional matrix adjust.
 Identities = 44/137 (33%), Positives = 62/137 (46%), Gaps = 8/137 (5%)

Query  33   APISWLGDVLQFGVPEGPVLELACGRSGTALGLAAAGRCVTAIDVSDTALVQLELEATRR  92
            AP  WL        P G VL+LACG    +  LAA G  V A+D    A+  L     RR
Sbjct  10   APSPWLTRWAHLIRPGGRVLDLACGSGRHSAWLAAQGFAVLAVDRDAEAIAALPSGIERR  69

Query  93   ELADRLTLVHADLCSWQSGD-GRFALVLCRLFWHPPTFRQACEAVAPGGVVAWEAWRRPI  151
                    V  +  +W   D GRF  V+   + H P +    EA+APGGV+ +E +    
Sbjct  70   T-------VDLEQGAWPLADAGRFDAVVVTNYLHRPLWPHLIEALAPGGVLIYETFAAGN  122

Query  152  DVARDTRRAEWCLKPGQ  168
            +      R ++ L+PG+
Sbjct  123  ETVGKPSRPDFLLRPGE  139


>gi|302548913|ref|ZP_07301255.1| methyltransferase type 11 [Streptomyces viridochromogenes DSM 
40736]
 gi|302466531|gb|EFL29624.1| methyltransferase type 11 [Streptomyces viridochromogenes DSM 
40736]
Length=181

 Score = 56.2 bits (134),  Expect = 3e-06, Method: Compositional matrix adjust.
 Identities = 41/103 (40%), Positives = 50/103 (49%), Gaps = 9/103 (8%)

Query  45   GVPEGPVLELACGRSGTALGLAAAGRCVTAIDVSDTALVQLELEATRRELADRLTLVHAD  104
            G+P G  L+L CG  G AL LA  G  VTA+D+S  A+ +L   A    L DR+  V  D
Sbjct  8    GLPPGEALDLGCGDGGDALWLAGQGWQVTAVDISAVAVERLAALAHSHALGDRVCTVRGD  67

Query  105  LCSWQSGDGRFALVLCRLFWHPP-------TFRQACEAVAPGG  140
            L    S  G F LV C  + H P         R A  A+ PGG
Sbjct  68   LHK-SSPPGEFDLV-CAHYLHTPFGLDRSTVLRSAAHALRPGG  108


>gi|288817454|ref|YP_003431801.1| tellurite resistance protein [Hydrogenobacter thermophilus TK-6]
 gi|288786853|dbj|BAI68600.1| tellurite resistance protein [Hydrogenobacter thermophilus TK-6]
 gi|308751061|gb|ADO44544.1| Methyltransferase type 11 [Hydrogenobacter thermophilus TK-6]
Length=180

 Score = 55.8 bits (133),  Expect = 4e-06, Method: Compositional matrix adjust.
 Identities = 46/172 (27%), Positives = 77/172 (45%), Gaps = 15/172 (8%)

Query  14   DRIRWNAKYECADPTEAVFAPISWLGDVLQFGVPEGPVLELACGRSGTALGLAAAGRCVT  73
            DR RW+ +Y     T+     + +         P G  LELACG    A+ LA  G  V 
Sbjct  5    DRERWDKRYAGGWKTQLHRTLLEFYH-----LAPVGKALELACGTGENAVFLAKVGFNVD  59

Query  74   AIDVSDTALVQLELEATRRELAD--RLTLVHADLCSWQSGDGRFALVLCRLFWHPPTFRQ  131
            AIDVS  A+ +    A +R L +  ++  + ADL  ++     + LV+   + +      
Sbjct  60   AIDVSCVAIDK----AKQRALEEGVQVNFICADLDEYKLSTDTYHLVINFYYLNRKLSEA  115

Query  132  ACEAVAPGGVVAWEAWRRPIDVARDTRRAEWCLKPGQPESELPAGFTVIRVV  183
              +A+ PGG++ +E +     + R+     + LK G    ELP  F  + ++
Sbjct  116  IVKALKPGGILIFETYNEKHIILREDFNPLYLLKCG----ELPDLFKDLELI  163


>gi|322418324|ref|YP_004197547.1| type 12 methyltransferase [Geobacter sp. M18]
 gi|320124711|gb|ADW12271.1| methyltransferase type 12 [Geobacter sp. M18]
Length=190

 Score = 55.5 bits (132),  Expect = 4e-06, Method: Compositional matrix adjust.
 Identities = 49/163 (31%), Positives = 76/163 (47%), Gaps = 18/163 (11%)

Query  14   DRIRWNAKYECADPTEAVFA--PISWLGDVLQ---FGVPEGPVLELACGRSGTALGLAAA  68
            DRI+W+ +Y      E VF+  P  +L D L+     +P    L+LACG    ++ LA  
Sbjct  4    DRIKWDERYSG---PENVFSLEPSRFLADSLRQILSLIPGKRALDLACGEGRNSIYLAQH  60

Query  69   GRCVTAIDVSDTALVQLELEATRR---ELADRLTLVHADLCSWQSGDGRFALVLCRLFWH  125
            G  V  +D+S        LE  RR   E+   +  + ADL  W+  +G + L+L   F  
Sbjct  61   GFEVAGVDISPRG-----LERARRRAAEVGVSVDFIEADLDQWRP-EGVYHLILNFNFLM  114

Query  126  PPTFRQACEAVAPGGVVAWEAWRRPIDVARDTRRAEWCLKPGQ  168
                    E +APGGVV  E       +  + R+ ++ L+PG+
Sbjct  115  RELIPSLVEVLAPGGVVLMETILDAPGLQGEHRK-DYLLQPGE  156


>gi|297560673|ref|YP_003679647.1| hypothetical protein Ndas_1712 [Nocardiopsis dassonvillei subsp. 
dassonvillei DSM 43111]
 gi|296845121|gb|ADH67141.1| protein of unknown function DUF664 [Nocardiopsis dassonvillei 
subsp. dassonvillei DSM 43111]
Length=396

 Score = 55.1 bits (131),  Expect = 5e-06, Method: Compositional matrix adjust.
 Identities = 50/149 (34%), Positives = 65/149 (44%), Gaps = 21/149 (14%)

Query  13   PDRIRWNAKYECADPT------EAVFAPISWLGDVLQFGVPEGP-------VLELACGRS  59
            P R  W  +Y   DP+       A FA ++  G++     PE          LELACGR 
Sbjct  9    PSREFWEPRYRGGDPSTPPPGPNAAFARLA--GELALVPPPEPERGADARRALELACGRG  66

Query  60   GTALGLAAAGRCVTAIDVSDTALVQLELEATRRELADRLTLVHADLCSWQSGDGRFALVL  119
            G AL LA  G  VTA+DV++ AL  L   A R  + DRLT    DL       G + LV 
Sbjct  67   GDALWLAGRGWDVTAVDVAEHALAVLAERARRAGVGDRLTTRRHDLALSVPDAGPWDLVY  126

Query  120  CRLFWHP------PTFRQACEAVAPGGVV  142
               F  P         R+   +V  GG++
Sbjct  127  ANYFHTPVDIDRDAVLRRVSRSVGGGGLL  155


>gi|257054281|ref|YP_003132113.1| methyltransferase family protein [Saccharomonospora viridis DSM 
43017]
 gi|256584153|gb|ACU95286.1| methyltransferase family protein [Saccharomonospora viridis DSM 
43017]
Length=208

 Score = 55.1 bits (131),  Expect = 5e-06, Method: Compositional matrix adjust.
 Identities = 40/103 (39%), Positives = 51/103 (50%), Gaps = 9/103 (8%)

Query  45   GVPEGPVLELACGRSGTALGLAAAGRCVTAIDVSDTALVQLELEATRRELADRLTLVHAD  104
            G+P G  L+L CG  G AL LA  G  VTA+D+S  A+ +L   A   +LADR+T V  D
Sbjct  35   GLPPGDALDLGCGNGGDALWLAGQGWHVTAVDISTVAVERLTALAASGDLADRVTAVRCD  94

Query  105  LCSWQSGDGRFALVLCRLFWHPP-------TFRQACEAVAPGG  140
            L       G F L+ C  + H P         R A  A+  GG
Sbjct  95   LGE-SFPAGEFDLI-CAHYLHTPFDLDRATVLRSAAHALRTGG  135


>gi|158520928|ref|YP_001528798.1| tellurite resistance protein TehB [Desulfococcus oleovorans Hxd3]
 gi|158509754|gb|ABW66721.1| Tellurite resistance protein TehB [Desulfococcus oleovorans Hxd3]
Length=183

 Score = 54.7 bits (130),  Expect = 7e-06, Method: Compositional matrix adjust.
 Identities = 51/187 (28%), Positives = 85/187 (46%), Gaps = 28/187 (14%)

Query  12   HPDRIRWNAKYE----CADPTEAVFAPISWLGDVLQFGVPEGPVLELACGRSGTALGLAA  67
            H DR RWN KY      A+P++ V    S            G  L++  G    ++ LA 
Sbjct  2    HEDRTRWNKKYTDREWTAEPSDIVRRFYSL--------AKPGMALDIGAGTGRNSVFLAE  53

Query  68   AGRCVTAIDVSDTALVQLELEATRRELADRLTLVHADLCSWQSGDGRFALVLCRLFWHPP  127
             G  V A+D+++  L Q+            L  V ADL  ++  + RF+L+   LF +  
Sbjct  54   QGFDVVAVDIAEKGLAQMAGAHAN------LLPVCADLDVFEIPENRFSLIANILFLNRR  107

Query  128  TFRQACEAVAPGGVVAWEAWRRPIDV--ARDTRRA-EWCLKPGQPESELPAGFTVIRVVD  184
             F    + +APGGV+ +E +   ID    R  RR+ ++CL     E+EL   F  + ++ 
Sbjct  108  LFPWIMDGLAPGGVLIFETY---IDFPSGRGHRRSRDFCL----AENELLYAFAPLHILY  160

Query  185  TDGSEPS  191
             + ++ +
Sbjct  161  YEETQKT  167


>gi|119475263|ref|ZP_01615616.1| hypothetical protein GP2143_15626 [marine gamma proteobacterium 
HTCC2143]
 gi|119451466|gb|EAW32699.1| hypothetical protein GP2143_15626 [marine gamma proteobacterium 
HTCC2143]
Length=193

 Score = 54.3 bits (129),  Expect = 1e-05, Method: Compositional matrix adjust.
 Identities = 39/139 (29%), Positives = 68/139 (49%), Gaps = 9/139 (6%)

Query  13   PDRIRWNAKYECA-DPTEAVFAPISWLGDVLQFGVPE-GPVLELACGRSGTALGLAAAGR  70
            P + +W+ +Y+ + DP         WL     + +P  G  L+LACG    AL LAA G 
Sbjct  5    PVQKKWDQRYQHSNDPGNPC-----WLLQNHSYLLPTTGRSLDLACGLGANALFLAAQGL  59

Query  71   CVTAIDVSDTALVQLELEATRRELADRLTLVHADLCSWQSGDGRFALVLCRLFWHPPTFR  130
               A D S  AL +L L ATR++ +  +T  H ++      +  F +++   F + P   
Sbjct  60   ESHAWDCSSVALKKLTLFATRQQFS--ITTQHREIEQHPPEENSFDIIVVSQFLYRPIMP  117

Query  131  QACEAVAPGGVVAWEAWRR  149
               +A+ PGG++ ++ + +
Sbjct  118  ALIDALLPGGLLFYQTFNQ  136


>gi|326777466|ref|ZP_08236731.1| Methyltransferase type 11 [Streptomyces cf. griseus XylebKG-1]
 gi|326657799|gb|EGE42645.1| Methyltransferase type 11 [Streptomyces griseus XylebKG-1]
Length=232

 Score = 54.3 bits (129),  Expect = 1e-05, Method: Compositional matrix adjust.
 Identities = 47/130 (37%), Positives = 60/130 (47%), Gaps = 16/130 (12%)

Query  52   LELACGRSGTALGLAAAGRCVTAIDVSDTALVQLELEATRRELADRLTLVHADLCSWQSG  111
            L+L CG  G AL LA+ G  VTA+DVS TAL ++   A    LADR+  V  DL      
Sbjct  64   LDLGCGHGGDALWLASLGWDVTAVDVSSTALGRVAAGAAEAGLADRVHPVRHDLAR-TFP  122

Query  112  DGRFALVLCRLFWHP------PTFRQACEAVAPGGVVAWEAWRRPIDVARDTRRAEWCLK  165
            +G F LV    F  P         R+A EAVAPGG++          +      A W  +
Sbjct  123  EGTFGLVTAGYFHTPVEIPREQVLRRAAEAVAPGGLLV---------LVEHASLAPWSWR  173

Query  166  PGQPESELPA  175
             G  +   PA
Sbjct  174  DGHEDVRFPA  183


>gi|319956879|ref|YP_004168142.1| methyltransferase type 11 [Nitratifractor salsuginis DSM 16511]
 gi|319419283|gb|ADV46393.1| Methyltransferase type 11 [Nitratifractor salsuginis DSM 16511]
Length=194

 Score = 54.3 bits (129),  Expect = 1e-05, Method: Compositional matrix adjust.
 Identities = 34/120 (29%), Positives = 57/120 (48%), Gaps = 0/120 (0%)

Query  49   GPVLELACGRSGTALGLAAAGRCVTAIDVSDTALVQLELEATRRELADRLTLVHADLCSW  108
            G  L+LACG     L LA  G  V A+D+S  AL  L  +A +  LADR+     DL ++
Sbjct  38   GLALDLACGTGRNTLALARRGWQVDAVDLSPVALQILTEQAQQSGLADRIRTSMEDLDTF  97

Query  109  QSGDGRFALVLCRLFWHPPTFRQACEAVAPGGVVAWEAWRRPIDVARDTRRAEWCLKPGQ  168
             + +  + L+L   +       +   A+  GG+   E + +  D  +     ++ L+PG+
Sbjct  98   SAPEEHYDLILMTNYLDRELIERIIPALKRGGIFVVETYMQHPDNEKPNGNPDYLLQPGE  157


>gi|182436871|ref|YP_001824590.1| putative methyltransferase [Streptomyces griseus subsp. griseus 
NBRC 13350]
 gi|178465387|dbj|BAG19907.1| putative methyltransferase [Streptomyces griseus subsp. griseus 
NBRC 13350]
Length=232

 Score = 54.3 bits (129),  Expect = 1e-05, Method: Compositional matrix adjust.
 Identities = 47/130 (37%), Positives = 60/130 (47%), Gaps = 16/130 (12%)

Query  52   LELACGRSGTALGLAAAGRCVTAIDVSDTALVQLELEATRRELADRLTLVHADLCSWQSG  111
            L+L CG  G AL LA+ G  VTA+DVS TAL ++   A    LADR+  V  DL      
Sbjct  64   LDLGCGHGGDALWLASLGWDVTAVDVSSTALGRVAAGAAEAGLADRVRPVRHDLAR-TFP  122

Query  112  DGRFALVLCRLFWHP------PTFRQACEAVAPGGVVAWEAWRRPIDVARDTRRAEWCLK  165
            +G F LV    F  P         R+A EAVAPGG++          +      A W  +
Sbjct  123  EGTFGLVTAGYFHTPVEIPREQVLRRAAEAVAPGGLLV---------LVEHASLAPWSWR  173

Query  166  PGQPESELPA  175
             G  +   PA
Sbjct  174  DGHEDVRFPA  183


>gi|197117283|ref|YP_002137710.1| SAM-dependent methyltransferase [Geobacter bemidjiensis Bem]
 gi|197086643|gb|ACH37914.1| SAM-dependent methyltransferase [Geobacter bemidjiensis Bem]
Length=190

 Score = 53.9 bits (128),  Expect = 1e-05, Method: Compositional matrix adjust.
 Identities = 52/193 (27%), Positives = 91/193 (48%), Gaps = 12/193 (6%)

Query  14   DRIRWNAKYECADPTEAVFAPISWLGD----VLQFGVPEGPVLELACGRSGTALGLAAAG  69
            DRI+W+ +Y   +   ++  P  +L D    VL   V     L+LACG    ++ LA  G
Sbjct  4    DRIKWDQRYRDVERFFSL-GPSRFLADSFARVLSL-VRGRRALDLACGEGRNSIYLAQQG  61

Query  70   RCVTAIDVSDTALVQLELEATRRELADRLTLVHADLCSWQSGDGRFALVLCRLFWHPPTF  129
              V+ +D+S   L + +  A   EL   +  + ADL  W+  +  + L+L   F      
Sbjct  62   FEVSGVDISPVGLERGKRRAA--ELGVPVEFIEADLDHWRPQES-YDLILNFNFLMRDLI  118

Query  130  RQACEAVAPGGVVAWEAWRRPIDVARDTRRAEWCLKPGQPESELPAGFTVIRVVDTDGSE  189
                EA++PGGVV  E       +  + RR ++ L+PG+  +        + +++ DG++
Sbjct  119  PALIEALSPGGVVLMETILDAPGLQGEHRR-DYLLQPGELGNIFEEFEGKVLLLEEDGAQ  177

Query  190  --PSRRIIAQRSL  200
              P  R++ Q+ L
Sbjct  178  EIPVARVLFQKRL  190


>gi|253701962|ref|YP_003023151.1| methyltransferase type 12 [Geobacter sp. M21]
 gi|251776812|gb|ACT19393.1| Methyltransferase type 12 [Geobacter sp. M21]
Length=190

 Score = 53.5 bits (127),  Expect = 2e-05, Method: Compositional matrix adjust.
 Identities = 51/192 (27%), Positives = 90/192 (47%), Gaps = 10/192 (5%)

Query  14   DRIRWNAKYECADPTEAVFAPISWLGDVLQ--FGVPEGP-VLELACGRSGTALGLAAAGR  70
            DRI+W+ +Y   +   ++  P  +L D L     +  G   L+LACG    ++ LA  G 
Sbjct  4    DRIKWDQRYRDVERFFSL-GPSRFLADSLTRILSLVRGRRALDLACGEGRNSIYLAQQGF  62

Query  71   CVTAIDVSDTALVQLELEATRRELADRLTLVHADLCSWQSGDGRFALVLCRLFWHPPTFR  130
             V+ +D+S   L + +  A   EL   +  + ADL  W+   G + L+L   F       
Sbjct  63   EVSGVDISPVGLERGKRRAA--ELGVPVEFIEADLDQWRP-QGGYDLILNFNFLMRGLLP  119

Query  131  QACEAVAPGGVVAWEAWRRPIDVARDTRRAEWCLKPGQPESELPAGFTVIRVVDTDGSE-  189
               EA++PGGVV  E       +  + RR ++ L+PG+  +        + +++ D ++ 
Sbjct  120  TLVEALSPGGVVLMETILDAPGLQGEHRR-DYLLQPGELGNIFEEFDGKVLLLEEDAAQE  178

Query  190  -PSRRIIAQRSL  200
             P  R++ Q+ L
Sbjct  179  TPVARMLFQKRL  190


>gi|198284892|ref|YP_002221213.1| type 12 methyltransferase [Acidithiobacillus ferrooxidans ATCC 
53993]
 gi|198249413|gb|ACH85006.1| Methyltransferase type 12 [Acidithiobacillus ferrooxidans ATCC 
53993]
 gi|339832755|gb|EGQ60648.1| type 12 methyltransferase [Acidithiobacillus sp. GGI-221]
Length=180

 Score = 53.5 bits (127),  Expect = 2e-05, Method: Compositional matrix adjust.
 Identities = 52/171 (31%), Positives = 77/171 (46%), Gaps = 13/171 (7%)

Query  8    LLADHPDRIRWNAKYECADPTEAVF-APISWLGDVLQFGVPEGPVLELACGRSGTALGLA  66
            ++A+   R RW+A   C   TE +   P+ +L     +    G  L+LACGR G AL LA
Sbjct  1    MMAEDEKRARWHA---CYAQTETLAPEPLPFLAAHADWLPASGRALDLACGRGGNALFLA  57

Query  67   AAGRCVTAIDVSDTALVQLELEATRRELADRLTLVHA--DLCSWQSGDGRFALVLCRLFW  124
              G    A D +++A+  L      R+ AD L L     D+ +       F +++   F 
Sbjct  58   RRGLKTWAWDYAESAVAGL------RQRADGLPLWVECRDVVTHPPEPESFDVIVVAHFL  111

Query  125  HPPTFRQACEAVAPGGVVAWEAWRRPIDVARDTRRAEWCLKPGQPESELPA  175
            H P F     A  PGG++ +E W       R  +  E+ LKPG+     PA
Sbjct  112  HRPLFPALAAAARPGGLLFYETWAGAY-AGRGPQNPEYRLKPGELAGAFPA  161


>gi|326316171|ref|YP_004233843.1| type 11 methyltransferase [Acidovorax avenae subsp. avenae ATCC 
19860]
 gi|323373007|gb|ADX45276.1| Methyltransferase type 11 [Acidovorax avenae subsp. avenae ATCC 
19860]
Length=195

 Score = 53.1 bits (126),  Expect = 2e-05, Method: Compositional matrix adjust.
 Identities = 54/170 (32%), Positives = 70/170 (42%), Gaps = 18/170 (10%)

Query  33   APISWLGDVLQFGVPEGPVLELACGRSGTALGLAAAGRCVTAIDVSDTALVQLELEATRR  92
            AP  W+          G VL++ACG         A G  VT +D S  A+          
Sbjct  17   APSGWITRWAHLVPLHGHVLDVACGSGRHLRWFHARGHAVTGVDRSAEAIA---------  67

Query  93   ELADRLTLVHADL--CSWQSGDGRF-ALVLCRLFWHPPTFRQACEAVAPGGVVAWEAWRR  149
             LA    LVHAD+    W     RF  +V+    W P        +VAPGGV+ +E + R
Sbjct  68   PLAQLGELVHADIEQGPWPFTGRRFDGVVVTHYLWRP-LLPALAASVAPGGVLLYETFAR  126

Query  150  PIDVARDTRRAEWCLKPGQPESELPAGFTVIRVVDT-DGSEPSRRIIAQR  198
                     R E+ L+PG    EL A F  +RV+   DG  PS     QR
Sbjct  127  GNGTVGRPSRPEFLLEPG----ELLAAFPGLRVIAYEDGFLPSPERFVQR  172


>gi|159038190|ref|YP_001537443.1| type 11 methyltransferase [Salinispora arenicola CNS-205]
 gi|157917025|gb|ABV98452.1| Methyltransferase type 11 [Salinispora arenicola CNS-205]
Length=208

 Score = 52.8 bits (125),  Expect = 3e-05, Method: Compositional matrix adjust.
 Identities = 46/129 (36%), Positives = 58/129 (45%), Gaps = 9/129 (6%)

Query  18   WNAKYECADPTEAVFAPISWLGDVLQFGVPEGPVLELACGRSGTALGLAAAGRCVTAIDV  77
            WN  Y  + P      P + L +V+   +P G  L+L CG  G AL LA  G  VTA D+
Sbjct  10   WNGVYS-SRPAATTPNPNARLTEVVT-NLPAGEALDLGCGTGGDALWLAGRGWRVTAADI  67

Query  78   SDTALVQLELEATRRELADRLTLVHADLCSWQSGDGRFALVLCRLFWHP------PTFRQ  131
            S  A+ +L   A    LADR+T V  DL S     G+F LV       P         R 
Sbjct  68   STVAVERLTTLAATLGLADRVTAVQCDLSSLFP-HGQFDLVSAHYLQTPLGLDRATVLRA  126

Query  132  ACEAVAPGG  140
            A  A+ P G
Sbjct  127  AAHALRPQG  135


>gi|126731920|ref|ZP_01747724.1| putative methyltransferase [Sagittula stellata E-37]
 gi|126707747|gb|EBA06809.1| putative methyltransferase [Sagittula stellata E-37]
Length=211

 Score = 52.8 bits (125),  Expect = 3e-05, Method: Compositional matrix adjust.
 Identities = 40/105 (39%), Positives = 52/105 (50%), Gaps = 9/105 (8%)

Query  45   GVPEGPVLELACGRSGTALGLAAAGRCVTAIDVSDTALVQLELEATRRELADRLTLVHAD  104
            G P G  ++L CGR   A+ LA  G  V A+DVS  AL  +   A    +A+R+T +  D
Sbjct  40   GRPAGRAVDLGCGRGDDAIWLARNGWKVVAVDVSQAALDTVRRNAETAGVAERVTWLRHD  99

Query  105  LCSWQSGDGRFALVLCRLFWHPP-------TFRQACEAVAPGGVV  142
            L      DG F LVL  +F H P         R A   VAPGG++
Sbjct  100  LSK-SLPDGPFDLVLS-MFTHTPLEFDRAAMLRAAATLVAPGGLL  142


>gi|297153463|gb|ADI03175.1| methyltransferase type 12 [Streptomyces bingchenggensis BCW-1]
Length=208

 Score = 52.4 bits (124),  Expect = 4e-05, Method: Compositional matrix adjust.
 Identities = 46/130 (36%), Positives = 60/130 (47%), Gaps = 11/130 (8%)

Query  18   WNAKYECADPTEAVFAPISWLGDVLQFGVPEGPVLELACGRSGTALGLAAAGRCVTAIDV  77
            W+  Y  A P      P + L + +  G+P G  L+L CG  G AL LA  G  VTA D+
Sbjct  10   WDGVY-AARPAAGNPQPNARLTETVT-GLPAGDALDLGCGDGGDALWLAGQGWQVTAADI  67

Query  78   SDTALVQLELEATRRELADRLTLVHADLCSWQSGDGRFALVLCRLFWHPP-------TFR  130
            S  A+ +L   A    L DR+T V  DL +     G F L+ C  + H P         R
Sbjct  68   SAVAVERLAALARAHGLGDRVTAVRHDLHT-SFPPGGFDLI-CAHYLHTPCDLDRATVLR  125

Query  131  QACEAVAPGG  140
             A  A+ PGG
Sbjct  126  SAAHALRPGG  135


>gi|218665549|ref|YP_002427572.1| hypothetical protein AFE_3216 [Acidithiobacillus ferrooxidans 
ATCC 23270]
 gi|218517762|gb|ACK78348.1| conserved hypothetical protein [Acidithiobacillus ferrooxidans 
ATCC 23270]
Length=179

 Score = 52.4 bits (124),  Expect = 4e-05, Method: Compositional matrix adjust.
 Identities = 52/170 (31%), Positives = 76/170 (45%), Gaps = 13/170 (7%)

Query  9    LADHPDRIRWNAKYECADPTEAVF-APISWLGDVLQFGVPEGPVLELACGRSGTALGLAA  67
            +A+   R RW+A   C   TE +   P+ +L     +    G  L+LACGR G AL LA 
Sbjct  1    MAEDEKRARWHA---CYAQTETLAPEPLPFLAAHADWLPASGRALDLACGRGGNALFLAR  57

Query  68   AGRCVTAIDVSDTALVQLELEATRRELADRLTLVHA--DLCSWQSGDGRFALVLCRLFWH  125
             G    A D +++A+  L      R+ AD L L     D+ +       F +++   F H
Sbjct  58   RGLKTWAWDYAESAVAGL------RQRADGLPLWVECRDVVTHPPEPESFDVIVVAHFLH  111

Query  126  PPTFRQACEAVAPGGVVAWEAWRRPIDVARDTRRAEWCLKPGQPESELPA  175
             P F     A  PGG++ +E W       R  +  E+ LKPG+     PA
Sbjct  112  RPLFPALAAAARPGGLLFYETWAGAY-AGRGPQNPEYRLKPGELAGAFPA  160


>gi|162450418|ref|YP_001612785.1| methyltransferase [Sorangium cellulosum 'So ce 56']
 gi|161161000|emb|CAN92305.1| putative Methyltransferase [Sorangium cellulosum 'So ce 56']
Length=206

 Score = 52.4 bits (124),  Expect = 4e-05, Method: Compositional matrix adjust.
 Identities = 42/115 (37%), Positives = 55/115 (48%), Gaps = 9/115 (7%)

Query  45   GVPEGPVLELACGRSGTALGLAAAGRCVTAIDVSDTALV--QLELEATRRELADRLTLVH  102
            G+  G  L+  CG     L LAA G  VTA+D S +AL   Q   EA   ++A+R+  V 
Sbjct  38   GLRPGRALDAGCGHGAETLWLAAHGWKVTAVDFSASALAHGQSTAEALGADIAERIAWVE  97

Query  103  ADLCSWQSGDGRFALVLCRLFWH-----PPTFRQACEAVAPGGVVAWEAWRRPID  152
             DL  W      F LV+C L+ H         R+    VAPGG + +    RPID
Sbjct  98   GDLAVWTPPRDHFDLVVC-LYVHVAGSVEDMVRRMASGVAPGGAL-FMVGHRPID  150


>gi|118470628|ref|YP_886876.1| thiopurine S-methyltransferase (tpmt) superfamily protein [Mycobacterium 
smegmatis str. MC2 155]
 gi|118171915|gb|ABK72811.1| thiopurine S-methyltransferase (tpmt) superfamily protein [Mycobacterium 
smegmatis str. MC2 155]
Length=226

 Score = 51.6 bits (122),  Expect = 6e-05, Method: Compositional matrix adjust.
 Identities = 47/160 (30%), Positives = 67/160 (42%), Gaps = 23/160 (14%)

Query  41   VLQFGVPEGPVLELACGRSGTALGLAAAGRCVTAIDVSDTALVQLELEATRRELADRLTL  100
            ++  G   G VL+  CG + TAL LAA G     +D S TA+     EA RR L +  T 
Sbjct  38   LIDAGKFHGEVLDAGCGEAATALYLAAQGFTTVGLDQSPTAIELARAEAARRGLTN-ATF  96

Query  101  VHADLCSWQSGDGRFALVLCRLFWH--PPTFRQACE-----AVAPGGVVAWEAWRR----  149
              AD+ S+   DGRF  ++    +H  P   R   +     A APG       + +    
Sbjct  97   EVADISSFTGYDGRFGTIVDSTLFHSMPVELRDGYQQSIVRAAAPGATYVVLVFDKTTMG  156

Query  150  ------PI--DVARDTRRAEWC---LKPGQPESELPAGFT  178
                  P+  D  RD     W    + P +  + +PA FT
Sbjct  157  DTGPANPVTDDELRDVVGRYWVIDDISPARIHANVPAEFT  196


>gi|95928815|ref|ZP_01311561.1| Methyltransferase type 11 [Desulfuromonas acetoxidans DSM 684]
 gi|95135160|gb|EAT16813.1| Methyltransferase type 11 [Desulfuromonas acetoxidans DSM 684]
Length=183

 Score = 51.6 bits (122),  Expect = 7e-05, Method: Compositional matrix adjust.
 Identities = 53/191 (28%), Positives = 81/191 (43%), Gaps = 19/191 (9%)

Query  17   RWNAKYECADPTEAVFAPISWLGDVLQFGVPEGPVLELACGRSGTALGLAAAGRCVTAID  76
             WN +++  +  E      +WL  +L      G VL++ACGR   A+ L   G  VTA+D
Sbjct  5    NWNQRWK--ERQERPLQADNWLLKMLPLLPETGTVLDIACGRGRNAVYLQQHGWQVTAVD  62

Query  77   VSDTALVQLELEATRRELADRLTLVHADLCSWQSGDGRFALVLCRLFWHPPTFRQACEAV  136
             SD AL QL+       +  ++   H DL        RF LVL   F +        + V
Sbjct  63   GSDEALHQLQ------SVCPQIITRHHDLDQPLELSQRFDLVLQFFFLNRRQLPHFMQQV  116

Query  137  APGGVVAWEAWRRPIDVARDTRRAEWCLKPGQPESELPAGFTVIRVV-DTDGSEPSRR--  193
             PGG +    +    +        E  L+PG    EL   F+   ++   +G +PS +  
Sbjct  117  RPGGAMIVRTFSDAGEFGSKGGNPEHRLQPG----ELLEIFSPWEILCHEEGLDPSHKGG  172

Query  194  ----IIAQRSL  200
                I+A+R L
Sbjct  173  SLAGIVARRPL  183


>gi|254564116|ref|YP_003071211.1| S-adenosyl-L-methionine-dependent methyltransferase [Methylobacterium 
extorquens DM4]
 gi|254271394|emb|CAX27407.1| putative S-adenosyl-L-methionine-dependent methyltransferase 
[Methylobacterium extorquens DM4]
Length=259

 Score = 51.2 bits (121),  Expect = 9e-05, Method: Compositional matrix adjust.
 Identities = 46/139 (34%), Positives = 58/139 (42%), Gaps = 25/139 (17%)

Query  47   PEGPVLELACGRSGTALGLAAAGRCVTAIDVSDTALVQLELEATRRELADRLTLVHADLC  106
            P   VL+L CG       +A   R VTA+D+S + L  +  EA RR LA+  T   A + 
Sbjct  44   PHAAVLDLGCGGGHVTYAVAPEVRSVTALDLSQSMLDAVAAEAKRRGLANVATR-QASVE  102

Query  107  SWQSGDGRFALVLCRLFWH-----PPTFRQACEAVAPGG------------------VVA  143
            +    D  F  VL R   H     P   R+A   +APGG                  + A
Sbjct  103  ALPFADASFDGVLSRYSAHHWGDVPAALREAHRVLAPGGRFGLVDVVHPGPPLLDTHLQA  162

Query  144  WEAWRRPIDVARDTRRAEW  162
            WE  R P  V RD   AEW
Sbjct  163  WELLRDPSHV-RDYGEAEW  180


>gi|84686208|ref|ZP_01014103.1| hypothetical protein 1099457000256_RB2654_08392 [Maritimibacter 
alkaliphilus HTCC2654]
 gi|84665735|gb|EAQ12210.1| hypothetical protein RB2654_08392 [Rhodobacterales bacterium 
HTCC2654]
Length=210

 Score = 50.8 bits (120),  Expect = 1e-04, Method: Compositional matrix adjust.
 Identities = 49/135 (37%), Positives = 58/135 (43%), Gaps = 11/135 (8%)

Query  15   RIRWNAKY-ECADPTEAVFAPISWLGDVLQFGVPEGPVLELACGRSGTALGLAAAGRCVT  73
            R  W  +Y    DPT     P   L  +    VP G  L++ C R   AL LAA G  VT
Sbjct  8    RTFWEDRYGAMTDPTNG--KPSGVLERLATGRVP-GRALDIGCARGDDALWLAATGWTVT  64

Query  74   AIDVSDTALVQLELEATRRELADRLTLVHADLCSWQSGDGRFALVLCRLFWHPPTFRQ--  131
             +DVS TAL      A    LADR+T     L      DG F LV    F  P  F +  
Sbjct  65   GVDVSQTALDIAADRARTAGLADRITFERHTLPE-TFPDGSFDLVSALFFQSPMAFDRAR  123

Query  132  ----ACEAVAPGGVV  142
                A  A APGG++
Sbjct  124  VLELAARATAPGGLL  138


>gi|240141606|ref|YP_002966086.1| S-adenosyl-L-methionine-dependent methyltransferase [methylobacterium 
extorquens AM1]
 gi|240011583|gb|ACS42809.1| putative S-adenosyl-L-methionine-dependent methyltransferase 
[Methylobacterium extorquens AM1]
Length=259

 Score = 50.8 bits (120),  Expect = 1e-04, Method: Compositional matrix adjust.
 Identities = 46/139 (34%), Positives = 58/139 (42%), Gaps = 25/139 (17%)

Query  47   PEGPVLELACGRSGTALGLAAAGRCVTAIDVSDTALVQLELEATRRELADRLTLVHADLC  106
            P   VL+L CG       +A   R VTA+D+S T L  +  EA RR LA+  T   A + 
Sbjct  44   PHAAVLDLGCGGGHVTYAVAPQVRSVTALDLSQTMLDAVAAEAQRRGLANVATR-RASVE  102

Query  107  SWQSGDGRFALVLCRLFWH-----PPTFRQACEAVAPGG------------------VVA  143
            +    D  F  V+ R   H     P   R+A   +APGG                  + A
Sbjct  103  ALPFADASFDGVVSRYSAHHWGDVPAALREAHRVLAPGGRFGLVDVVHPGPPLLDTHLQA  162

Query  144  WEAWRRPIDVARDTRRAEW  162
            WE  R P  V RD   AEW
Sbjct  163  WELLRDPSHV-RDYGEAEW  180


>gi|315443843|ref|YP_004076722.1| methylase involved in ubiquinone/menaquinone biosynthesis [Mycobacterium 
sp. Spyr1]
 gi|315262146|gb|ADT98887.1| methylase involved in ubiquinone/menaquinone biosynthesis [Mycobacterium 
sp. Spyr1]
Length=206

 Score = 50.4 bits (119),  Expect = 1e-04, Method: Compositional matrix adjust.
 Identities = 41/100 (41%), Positives = 50/100 (50%), Gaps = 7/100 (7%)

Query  49   GPVLELACGRSGTALGLAAAGRCVTAIDVSDTALVQLELEATRRELADRLTLVHADLCSW  108
            G  L+L CG  G  L LA  G  V  +D+SDTAL +   EA +R LADR+ L   DL + 
Sbjct  37   GRALDLGCGEGGDTLWLAEHGWEVVGVDISDTALRRAAEEADKRGLADRVQLRQTDLSA-  95

Query  109  QSGDGRFALVLCRLFW------HPPTFRQACEAVAPGGVV  142
               DG F LV  +             F  A  AVAPGGV+
Sbjct  96   SFPDGVFDLVSAQFLQSMVHLDRERIFAAAARAVAPGGVL  135



Lambda     K      H
   0.322    0.136    0.443 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Effective search space used: 218250040016


  Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
    Posted date:  Sep 5, 2011  4:36 AM
  Number of letters in database: 5,219,829,388
  Number of sequences in database:  15,229,318



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40