BLASTP 2.2.25+
Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
15,229,318 sequences; 5,219,829,388 total letters
Query= Rv3132c
Length=578
Score E
Sequences producing significant alignments: (Bits) Value
gi|15610268|ref|NP_217648.1| two component sensor histidine kina... 1139 0.0
gi|289763315|ref|ZP_06522693.1| two component sensor histidine k... 1139 0.0
gi|31794308|ref|NP_856801.1| two component sensor histidine kina... 1137 0.0
gi|289448811|ref|ZP_06438555.1| two component system sensor hist... 1137 0.0
gi|340628108|ref|YP_004746560.1| two component sensor histidine ... 1135 0.0
gi|183981532|ref|YP_001849823.1| two-component sensor histidine ... 841 0.0
gi|118617913|ref|YP_906245.1| two component sensor histidine kin... 837 0.0
gi|240168621|ref|ZP_04747280.1| two component sensor histidine k... 829 0.0
gi|118468427|ref|YP_889487.1| GAF family protein [Mycobacterium ... 711 0.0
gi|333991619|ref|YP_004524233.1| two-component sensor histidine ... 707 0.0
gi|120402406|ref|YP_952235.1| GAF sensor signal transduction his... 675 0.0
gi|108801089|ref|YP_641286.1| putative signal transduction histi... 671 0.0
gi|108798050|ref|YP_638247.1| GAF sensor signal transduction his... 668 0.0
gi|126436927|ref|YP_001072618.1| GAF sensor signal transduction ... 668 0.0
gi|315444759|ref|YP_004077638.1| histidine kinase with GAF domai... 645 0.0
gi|145224426|ref|YP_001135104.1| GAF sensor signal transduction ... 645 0.0
gi|15609164|ref|NP_216543.1| histidine kinase response regulator... 626 4e-177
gi|31793209|ref|NP_855702.1| histidine kinase response regulator... 624 1e-176
gi|167970443|ref|ZP_02552720.1| hypothetical histidine kinase re... 622 4e-176
gi|340627038|ref|YP_004745490.1| putative histidine kinase respo... 613 4e-173
gi|333919784|ref|YP_004493365.1| GAF sensor signal transduction ... 604 1e-170
gi|111017071|ref|YP_700043.1| sensor kinase, two-component syste... 596 5e-168
gi|226359607|ref|YP_002777385.1| two-component histidine kinase ... 577 3e-162
gi|302526810|ref|ZP_07279152.1| predicted protein [Streptomyces ... 533 3e-149
gi|343925109|ref|ZP_08764641.1| two-component histidine kinase D... 526 4e-147
gi|326385155|ref|ZP_08206823.1| sensor kinase, two-component sys... 525 1e-146
gi|317507620|ref|ZP_07965333.1| GAF domain-containing protein [S... 512 7e-143
gi|54024863|ref|YP_119105.1| putative two-component system senso... 504 1e-140
gi|169630969|ref|YP_001704618.1| histidine kinase response regul... 488 1e-135
gi|226306907|ref|YP_002766867.1| two-component histidine kinase ... 488 2e-135
gi|258652223|ref|YP_003201379.1| GAF sensor signal transduction ... 486 4e-135
gi|300787342|ref|YP_003767633.1| two-component system sensor kin... 474 1e-131
gi|296394764|ref|YP_003659648.1| GAF sensor signal transduction ... 457 3e-126
gi|72163445|ref|YP_291102.1| GAF:ATP-binding protein [Thermobifi... 412 9e-113
gi|240171513|ref|ZP_04750172.1| two-component sensor histidine k... 407 2e-111
gi|296171252|ref|ZP_06852656.1| GAF family protein [Mycobacteriu... 398 1e-108
gi|300787438|ref|YP_003767729.1| two-component system sensor kin... 397 2e-108
gi|296169095|ref|ZP_06850754.1| GAF family protein [Mycobacteriu... 395 1e-107
gi|41409368|ref|NP_962204.1| hypothetical protein MAP3270c [Myco... 393 5e-107
gi|288917580|ref|ZP_06411944.1| GAF sensor signal transduction h... 392 7e-107
gi|256376041|ref|YP_003099701.1| GAF sensor signal transduction ... 392 9e-107
gi|158313804|ref|YP_001506312.1| GAF sensor signal transduction ... 392 1e-106
gi|336459463|gb|EGO38403.1| histidine kinase,GAF domain-containi... 391 1e-106
gi|183983462|ref|YP_001851753.1| two-component sensor histidine ... 391 2e-106
gi|254776534|ref|ZP_05218050.1| hypothetical protein MaviaA2_179... 389 6e-106
gi|118467162|ref|YP_883257.1| GAF family protein [Mycobacterium ... 388 1e-105
gi|340528954|gb|AEK44159.1| two-component system sensor kinase [... 387 3e-105
gi|337764230|emb|CCB72939.1| Two-component sensor [Streptomyces ... 385 1e-104
gi|336179935|ref|YP_004585310.1| putative signal transduction hi... 384 2e-104
gi|296269629|ref|YP_003652261.1| GAF sensor signal transduction ... 383 5e-104
>gi|15610268|ref|NP_217648.1| two component sensor histidine kinase DEVS [Mycobacterium tuberculosis
H37Rv]
gi|15842705|ref|NP_337742.1| GAF family protein [Mycobacterium tuberculosis CDC1551]
gi|148662986|ref|YP_001284509.1| two component sensor histidine kinase DevS [Mycobacterium tuberculosis
H37Ra]
56 more sequence titles
Length=578
Score = 1139 bits (2947), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 578/578 (100%), Positives = 578/578 (100%), Gaps = 0/578 (0%)
Query 1 MTTGGLVDENDGAAMRPLRHTLSQLRLHELLVEVQDRVEQIVEGRDRLDGLVEAMLVVTA 60
MTTGGLVDENDGAAMRPLRHTLSQLRLHELLVEVQDRVEQIVEGRDRLDGLVEAMLVVTA
Sbjct 1 MTTGGLVDENDGAAMRPLRHTLSQLRLHELLVEVQDRVEQIVEGRDRLDGLVEAMLVVTA 60
Query 61 GLDLEATLRAIVHSATSLVDARYGAMEVHDRQHRVLHFVYEGIDEETVRRIGHLPKGLGV 120
GLDLEATLRAIVHSATSLVDARYGAMEVHDRQHRVLHFVYEGIDEETVRRIGHLPKGLGV
Sbjct 61 GLDLEATLRAIVHSATSLVDARYGAMEVHDRQHRVLHFVYEGIDEETVRRIGHLPKGLGV 120
Query 121 IGLLIEDPKPLRLDDVSAHPASIGFPPYHPPMRTFLGVPVRVRDESFGTLYLTDKTNGQP 180
IGLLIEDPKPLRLDDVSAHPASIGFPPYHPPMRTFLGVPVRVRDESFGTLYLTDKTNGQP
Sbjct 121 IGLLIEDPKPLRLDDVSAHPASIGFPPYHPPMRTFLGVPVRVRDESFGTLYLTDKTNGQP 180
Query 181 FSDDDEVLVQALAAAAGIAVANARLYQQAKARQSWIEATRDIATELLSGTEPATVFRLVA 240
FSDDDEVLVQALAAAAGIAVANARLYQQAKARQSWIEATRDIATELLSGTEPATVFRLVA
Sbjct 181 FSDDDEVLVQALAAAAGIAVANARLYQQAKARQSWIEATRDIATELLSGTEPATVFRLVA 240
Query 241 AEALKLTAADAALVAVPVDEDMPAADVGELLVIETVGSAVASIVGRTIPVAGAVLREVFV 300
AEALKLTAADAALVAVPVDEDMPAADVGELLVIETVGSAVASIVGRTIPVAGAVLREVFV
Sbjct 241 AEALKLTAADAALVAVPVDEDMPAADVGELLVIETVGSAVASIVGRTIPVAGAVLREVFV 300
Query 301 NGIPRRVDRVDLEGLDELADAGPALLLPLRARGTVAGVVVVLSQGGPGAFTDEQLEMMAA 360
NGIPRRVDRVDLEGLDELADAGPALLLPLRARGTVAGVVVVLSQGGPGAFTDEQLEMMAA
Sbjct 301 NGIPRRVDRVDLEGLDELADAGPALLLPLRARGTVAGVVVVLSQGGPGAFTDEQLEMMAA 360
Query 361 FADQAALAWQLATSQRRMRELDVLTDRDRIARDLHDHVIQRLFAIGLALQGAVPHERNPE 420
FADQAALAWQLATSQRRMRELDVLTDRDRIARDLHDHVIQRLFAIGLALQGAVPHERNPE
Sbjct 361 FADQAALAWQLATSQRRMRELDVLTDRDRIARDLHDHVIQRLFAIGLALQGAVPHERNPE 420
Query 421 VQQRLSDVVDDLQDVIQEIRTTIYDLHGASQGITRLRQRIDAAVAQFADSGLRTSVQFVG 480
VQQRLSDVVDDLQDVIQEIRTTIYDLHGASQGITRLRQRIDAAVAQFADSGLRTSVQFVG
Sbjct 421 VQQRLSDVVDDLQDVIQEIRTTIYDLHGASQGITRLRQRIDAAVAQFADSGLRTSVQFVG 480
Query 481 PLSVVDSALADQAEAVVREAVSNAVRHAKASTLTVRVKVDDDLCIEVTDNGRGLPDEFTG 540
PLSVVDSALADQAEAVVREAVSNAVRHAKASTLTVRVKVDDDLCIEVTDNGRGLPDEFTG
Sbjct 481 PLSVVDSALADQAEAVVREAVSNAVRHAKASTLTVRVKVDDDLCIEVTDNGRGLPDEFTG 540
Query 541 SGLTNLRQRAEQAGGEFTLASVPGASGTVLRWSAPLSQ 578
SGLTNLRQRAEQAGGEFTLASVPGASGTVLRWSAPLSQ
Sbjct 541 SGLTNLRQRAEQAGGEFTLASVPGASGTVLRWSAPLSQ 578
>gi|289763315|ref|ZP_06522693.1| two component sensor histidine kinase devS [Mycobacterium tuberculosis
GM 1503]
gi|289710821|gb|EFD74837.1| two component sensor histidine kinase devS [Mycobacterium tuberculosis
GM 1503]
Length=578
Score = 1139 bits (2945), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 577/578 (99%), Positives = 577/578 (99%), Gaps = 0/578 (0%)
Query 1 MTTGGLVDENDGAAMRPLRHTLSQLRLHELLVEVQDRVEQIVEGRDRLDGLVEAMLVVTA 60
MTTGGLVDENDGAAMRPLRHTLSQLRLHELLVEVQDRVEQIVEGRDRLDGLVEAMLVVTA
Sbjct 1 MTTGGLVDENDGAAMRPLRHTLSQLRLHELLVEVQDRVEQIVEGRDRLDGLVEAMLVVTA 60
Query 61 GLDLEATLRAIVHSATSLVDARYGAMEVHDRQHRVLHFVYEGIDEETVRRIGHLPKGLGV 120
GLDLEATLRAIVHSATSLVDARYGAMEVHDRQHRVLHFVYEGIDEETVRRIGHLPKGLGV
Sbjct 61 GLDLEATLRAIVHSATSLVDARYGAMEVHDRQHRVLHFVYEGIDEETVRRIGHLPKGLGV 120
Query 121 IGLLIEDPKPLRLDDVSAHPASIGFPPYHPPMRTFLGVPVRVRDESFGTLYLTDKTNGQP 180
IGLLIEDPKPLRLDDVSAHPASIGFPPYHPPMRTFLGVPVRVRDESFGTLYLTDKTNGQP
Sbjct 121 IGLLIEDPKPLRLDDVSAHPASIGFPPYHPPMRTFLGVPVRVRDESFGTLYLTDKTNGQP 180
Query 181 FSDDDEVLVQALAAAAGIAVANARLYQQAKARQSWIEATRDIATELLSGTEPATVFRLVA 240
FSDDDEVLVQALAAAAGIAVANARLYQQ KARQSWIEATRDIATELLSGTEPATVFRLVA
Sbjct 181 FSDDDEVLVQALAAAAGIAVANARLYQQVKARQSWIEATRDIATELLSGTEPATVFRLVA 240
Query 241 AEALKLTAADAALVAVPVDEDMPAADVGELLVIETVGSAVASIVGRTIPVAGAVLREVFV 300
AEALKLTAADAALVAVPVDEDMPAADVGELLVIETVGSAVASIVGRTIPVAGAVLREVFV
Sbjct 241 AEALKLTAADAALVAVPVDEDMPAADVGELLVIETVGSAVASIVGRTIPVAGAVLREVFV 300
Query 301 NGIPRRVDRVDLEGLDELADAGPALLLPLRARGTVAGVVVVLSQGGPGAFTDEQLEMMAA 360
NGIPRRVDRVDLEGLDELADAGPALLLPLRARGTVAGVVVVLSQGGPGAFTDEQLEMMAA
Sbjct 301 NGIPRRVDRVDLEGLDELADAGPALLLPLRARGTVAGVVVVLSQGGPGAFTDEQLEMMAA 360
Query 361 FADQAALAWQLATSQRRMRELDVLTDRDRIARDLHDHVIQRLFAIGLALQGAVPHERNPE 420
FADQAALAWQLATSQRRMRELDVLTDRDRIARDLHDHVIQRLFAIGLALQGAVPHERNPE
Sbjct 361 FADQAALAWQLATSQRRMRELDVLTDRDRIARDLHDHVIQRLFAIGLALQGAVPHERNPE 420
Query 421 VQQRLSDVVDDLQDVIQEIRTTIYDLHGASQGITRLRQRIDAAVAQFADSGLRTSVQFVG 480
VQQRLSDVVDDLQDVIQEIRTTIYDLHGASQGITRLRQRIDAAVAQFADSGLRTSVQFVG
Sbjct 421 VQQRLSDVVDDLQDVIQEIRTTIYDLHGASQGITRLRQRIDAAVAQFADSGLRTSVQFVG 480
Query 481 PLSVVDSALADQAEAVVREAVSNAVRHAKASTLTVRVKVDDDLCIEVTDNGRGLPDEFTG 540
PLSVVDSALADQAEAVVREAVSNAVRHAKASTLTVRVKVDDDLCIEVTDNGRGLPDEFTG
Sbjct 481 PLSVVDSALADQAEAVVREAVSNAVRHAKASTLTVRVKVDDDLCIEVTDNGRGLPDEFTG 540
Query 541 SGLTNLRQRAEQAGGEFTLASVPGASGTVLRWSAPLSQ 578
SGLTNLRQRAEQAGGEFTLASVPGASGTVLRWSAPLSQ
Sbjct 541 SGLTNLRQRAEQAGGEFTLASVPGASGTVLRWSAPLSQ 578
>gi|31794308|ref|NP_856801.1| two component sensor histidine kinase DEVS [Mycobacterium bovis
AF2122/97]
gi|121639015|ref|YP_979239.1| two component sensor histidine kinase devS [Mycobacterium bovis
BCG str. Pasteur 1173P2]
gi|224991507|ref|YP_002646196.1| two component sensor histidine kinase [Mycobacterium bovis BCG
str. Tokyo 172]
16 more sequence titles
Length=578
Score = 1137 bits (2941), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 577/578 (99%), Positives = 577/578 (99%), Gaps = 0/578 (0%)
Query 1 MTTGGLVDENDGAAMRPLRHTLSQLRLHELLVEVQDRVEQIVEGRDRLDGLVEAMLVVTA 60
MTTGGLVDENDGAAMRPLRHTLSQLRLHELLVEVQDRVEQIVEGRDRLDGLVEAMLVVTA
Sbjct 1 MTTGGLVDENDGAAMRPLRHTLSQLRLHELLVEVQDRVEQIVEGRDRLDGLVEAMLVVTA 60
Query 61 GLDLEATLRAIVHSATSLVDARYGAMEVHDRQHRVLHFVYEGIDEETVRRIGHLPKGLGV 120
GLDLEATLRAIVHSATSLVDARYGAMEVHDRQHRVLHFVYEGIDEETVRRIGHLPKGLGV
Sbjct 61 GLDLEATLRAIVHSATSLVDARYGAMEVHDRQHRVLHFVYEGIDEETVRRIGHLPKGLGV 120
Query 121 IGLLIEDPKPLRLDDVSAHPASIGFPPYHPPMRTFLGVPVRVRDESFGTLYLTDKTNGQP 180
IGLLIEDPKPLRLDDVSAHPASIGFPPYHPPMRTFLGVPVRVRDESFGTLYLTDKTNGQP
Sbjct 121 IGLLIEDPKPLRLDDVSAHPASIGFPPYHPPMRTFLGVPVRVRDESFGTLYLTDKTNGQP 180
Query 181 FSDDDEVLVQALAAAAGIAVANARLYQQAKARQSWIEATRDIATELLSGTEPATVFRLVA 240
FSDDDEVLVQALAAAAGIAVANARLYQQAKARQSWIEATRDIATELLSGTEPATVFRLVA
Sbjct 181 FSDDDEVLVQALAAAAGIAVANARLYQQAKARQSWIEATRDIATELLSGTEPATVFRLVA 240
Query 241 AEALKLTAADAALVAVPVDEDMPAADVGELLVIETVGSAVASIVGRTIPVAGAVLREVFV 300
AEALKLTAADAALVAVPVDEDMPAADVGELLVIETVGSAVAS VGRTIPVAGAVLREVFV
Sbjct 241 AEALKLTAADAALVAVPVDEDMPAADVGELLVIETVGSAVASTVGRTIPVAGAVLREVFV 300
Query 301 NGIPRRVDRVDLEGLDELADAGPALLLPLRARGTVAGVVVVLSQGGPGAFTDEQLEMMAA 360
NGIPRRVDRVDLEGLDELADAGPALLLPLRARGTVAGVVVVLSQGGPGAFTDEQLEMMAA
Sbjct 301 NGIPRRVDRVDLEGLDELADAGPALLLPLRARGTVAGVVVVLSQGGPGAFTDEQLEMMAA 360
Query 361 FADQAALAWQLATSQRRMRELDVLTDRDRIARDLHDHVIQRLFAIGLALQGAVPHERNPE 420
FADQAALAWQLATSQRRMRELDVLTDRDRIARDLHDHVIQRLFAIGLALQGAVPHERNPE
Sbjct 361 FADQAALAWQLATSQRRMRELDVLTDRDRIARDLHDHVIQRLFAIGLALQGAVPHERNPE 420
Query 421 VQQRLSDVVDDLQDVIQEIRTTIYDLHGASQGITRLRQRIDAAVAQFADSGLRTSVQFVG 480
VQQRLSDVVDDLQDVIQEIRTTIYDLHGASQGITRLRQRIDAAVAQFADSGLRTSVQFVG
Sbjct 421 VQQRLSDVVDDLQDVIQEIRTTIYDLHGASQGITRLRQRIDAAVAQFADSGLRTSVQFVG 480
Query 481 PLSVVDSALADQAEAVVREAVSNAVRHAKASTLTVRVKVDDDLCIEVTDNGRGLPDEFTG 540
PLSVVDSALADQAEAVVREAVSNAVRHAKASTLTVRVKVDDDLCIEVTDNGRGLPDEFTG
Sbjct 481 PLSVVDSALADQAEAVVREAVSNAVRHAKASTLTVRVKVDDDLCIEVTDNGRGLPDEFTG 540
Query 541 SGLTNLRQRAEQAGGEFTLASVPGASGTVLRWSAPLSQ 578
SGLTNLRQRAEQAGGEFTLASVPGASGTVLRWSAPLSQ
Sbjct 541 SGLTNLRQRAEQAGGEFTLASVPGASGTVLRWSAPLSQ 578
>gi|289448811|ref|ZP_06438555.1| two component system sensor histidine kinase devS [Mycobacterium
tuberculosis CPHL_A]
gi|289421769|gb|EFD18970.1| two component system sensor histidine kinase devS [Mycobacterium
tuberculosis CPHL_A]
Length=578
Score = 1137 bits (2940), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 576/578 (99%), Positives = 577/578 (99%), Gaps = 0/578 (0%)
Query 1 MTTGGLVDENDGAAMRPLRHTLSQLRLHELLVEVQDRVEQIVEGRDRLDGLVEAMLVVTA 60
MTTGGL+DENDGAAMRPLRHTLSQLRLHELLVEVQDRVEQIVEGRDRLDGLVEAMLVVTA
Sbjct 1 MTTGGLIDENDGAAMRPLRHTLSQLRLHELLVEVQDRVEQIVEGRDRLDGLVEAMLVVTA 60
Query 61 GLDLEATLRAIVHSATSLVDARYGAMEVHDRQHRVLHFVYEGIDEETVRRIGHLPKGLGV 120
GLDLEATLRAIVHSATSLVDARYGAMEVHDRQHRVLHFVYEGIDEETVRRIGHLPKGLGV
Sbjct 61 GLDLEATLRAIVHSATSLVDARYGAMEVHDRQHRVLHFVYEGIDEETVRRIGHLPKGLGV 120
Query 121 IGLLIEDPKPLRLDDVSAHPASIGFPPYHPPMRTFLGVPVRVRDESFGTLYLTDKTNGQP 180
IGLLIEDPKPLRLDDVSAHPASIGFPPYHPPMRTFLGVPVRVRDESFGTLYLTDKTNGQP
Sbjct 121 IGLLIEDPKPLRLDDVSAHPASIGFPPYHPPMRTFLGVPVRVRDESFGTLYLTDKTNGQP 180
Query 181 FSDDDEVLVQALAAAAGIAVANARLYQQAKARQSWIEATRDIATELLSGTEPATVFRLVA 240
FSDDDEVLVQALAAAAGIAVANARLYQQAKARQSWIEATRDIATELLSGTEPATVFRLVA
Sbjct 181 FSDDDEVLVQALAAAAGIAVANARLYQQAKARQSWIEATRDIATELLSGTEPATVFRLVA 240
Query 241 AEALKLTAADAALVAVPVDEDMPAADVGELLVIETVGSAVASIVGRTIPVAGAVLREVFV 300
AEALKLTAADAALVAVPVDEDMPAADVGELLVIETVGSAVAS VGRTIPVAGAVLREVFV
Sbjct 241 AEALKLTAADAALVAVPVDEDMPAADVGELLVIETVGSAVASTVGRTIPVAGAVLREVFV 300
Query 301 NGIPRRVDRVDLEGLDELADAGPALLLPLRARGTVAGVVVVLSQGGPGAFTDEQLEMMAA 360
NGIPRRVDRVDLEGLDELADAGPALLLPLRARGTVAGVVVVLSQGGPGAFTDEQLEMMAA
Sbjct 301 NGIPRRVDRVDLEGLDELADAGPALLLPLRARGTVAGVVVVLSQGGPGAFTDEQLEMMAA 360
Query 361 FADQAALAWQLATSQRRMRELDVLTDRDRIARDLHDHVIQRLFAIGLALQGAVPHERNPE 420
FADQAALAWQLATSQRRMRELDVLTDRDRIARDLHDHVIQRLFAIGLALQGAVPHERNPE
Sbjct 361 FADQAALAWQLATSQRRMRELDVLTDRDRIARDLHDHVIQRLFAIGLALQGAVPHERNPE 420
Query 421 VQQRLSDVVDDLQDVIQEIRTTIYDLHGASQGITRLRQRIDAAVAQFADSGLRTSVQFVG 480
VQQRLSDVVDDLQDVIQEIRTTIYDLHGASQGITRLRQRIDAAVAQFADSGLRTSVQFVG
Sbjct 421 VQQRLSDVVDDLQDVIQEIRTTIYDLHGASQGITRLRQRIDAAVAQFADSGLRTSVQFVG 480
Query 481 PLSVVDSALADQAEAVVREAVSNAVRHAKASTLTVRVKVDDDLCIEVTDNGRGLPDEFTG 540
PLSVVDSALADQAEAVVREAVSNAVRHAKASTLTVRVKVDDDLCIEVTDNGRGLPDEFTG
Sbjct 481 PLSVVDSALADQAEAVVREAVSNAVRHAKASTLTVRVKVDDDLCIEVTDNGRGLPDEFTG 540
Query 541 SGLTNLRQRAEQAGGEFTLASVPGASGTVLRWSAPLSQ 578
SGLTNLRQRAEQAGGEFTLASVPGASGTVLRWSAPLSQ
Sbjct 541 SGLTNLRQRAEQAGGEFTLASVPGASGTVLRWSAPLSQ 578
>gi|340628108|ref|YP_004746560.1| two component sensor histidine kinase DEVS [Mycobacterium canettii
CIPT 140010059]
gi|340006298|emb|CCC45477.1| two component sensor histidine kinase DEVS [Mycobacterium canettii
CIPT 140010059]
Length=578
Score = 1135 bits (2936), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 576/578 (99%), Positives = 576/578 (99%), Gaps = 0/578 (0%)
Query 1 MTTGGLVDENDGAAMRPLRHTLSQLRLHELLVEVQDRVEQIVEGRDRLDGLVEAMLVVTA 60
MTTGGLVDENDGAAMRPLRHTLSQLRLHELLVEVQDRVEQIVEGRDRLDGLVEAMLVVTA
Sbjct 1 MTTGGLVDENDGAAMRPLRHTLSQLRLHELLVEVQDRVEQIVEGRDRLDGLVEAMLVVTA 60
Query 61 GLDLEATLRAIVHSATSLVDARYGAMEVHDRQHRVLHFVYEGIDEETVRRIGHLPKGLGV 120
GLDLEATLRAIVHSA SLVDARYGAMEVHDRQHRVLHFVYEGIDEETVRRIGHLPKGLGV
Sbjct 61 GLDLEATLRAIVHSAASLVDARYGAMEVHDRQHRVLHFVYEGIDEETVRRIGHLPKGLGV 120
Query 121 IGLLIEDPKPLRLDDVSAHPASIGFPPYHPPMRTFLGVPVRVRDESFGTLYLTDKTNGQP 180
IGLLIEDPKPLRLDDVSAHPASIGFPPYHPPMRTFLGVPVRVRDESFGTLYLTDKTNGQP
Sbjct 121 IGLLIEDPKPLRLDDVSAHPASIGFPPYHPPMRTFLGVPVRVRDESFGTLYLTDKTNGQP 180
Query 181 FSDDDEVLVQALAAAAGIAVANARLYQQAKARQSWIEATRDIATELLSGTEPATVFRLVA 240
FSDDDEVLVQALAAAAGIAVANARLYQQAKARQSWIEATRDIATELLSGTEPATVFRLVA
Sbjct 181 FSDDDEVLVQALAAAAGIAVANARLYQQAKARQSWIEATRDIATELLSGTEPATVFRLVA 240
Query 241 AEALKLTAADAALVAVPVDEDMPAADVGELLVIETVGSAVASIVGRTIPVAGAVLREVFV 300
AEALKLTAADAALVAVPVDEDMPAADVGELLVIETVGSAVAS VGRTIPVAGAVLREVFV
Sbjct 241 AEALKLTAADAALVAVPVDEDMPAADVGELLVIETVGSAVASTVGRTIPVAGAVLREVFV 300
Query 301 NGIPRRVDRVDLEGLDELADAGPALLLPLRARGTVAGVVVVLSQGGPGAFTDEQLEMMAA 360
NGIPRRVDRVDLEGLDELADAGPALLLPLRARGTVAGVVVVLSQGGPGAFTDEQLEMMAA
Sbjct 301 NGIPRRVDRVDLEGLDELADAGPALLLPLRARGTVAGVVVVLSQGGPGAFTDEQLEMMAA 360
Query 361 FADQAALAWQLATSQRRMRELDVLTDRDRIARDLHDHVIQRLFAIGLALQGAVPHERNPE 420
FADQAALAWQLATSQRRMRELDVLTDRDRIARDLHDHVIQRLFAIGLALQGAVPHERNPE
Sbjct 361 FADQAALAWQLATSQRRMRELDVLTDRDRIARDLHDHVIQRLFAIGLALQGAVPHERNPE 420
Query 421 VQQRLSDVVDDLQDVIQEIRTTIYDLHGASQGITRLRQRIDAAVAQFADSGLRTSVQFVG 480
VQQRLSDVVDDLQDVIQEIRTTIYDLHGASQGITRLRQRIDAAVAQFADSGLRTSVQFVG
Sbjct 421 VQQRLSDVVDDLQDVIQEIRTTIYDLHGASQGITRLRQRIDAAVAQFADSGLRTSVQFVG 480
Query 481 PLSVVDSALADQAEAVVREAVSNAVRHAKASTLTVRVKVDDDLCIEVTDNGRGLPDEFTG 540
PLSVVDSALADQAEAVVREAVSNAVRHAKASTLTVRVKVDDDLCIEVTDNGRGLPDEFTG
Sbjct 481 PLSVVDSALADQAEAVVREAVSNAVRHAKASTLTVRVKVDDDLCIEVTDNGRGLPDEFTG 540
Query 541 SGLTNLRQRAEQAGGEFTLASVPGASGTVLRWSAPLSQ 578
SGLTNLRQRAEQAGGEFTLASVPGASGTVLRWSAPLSQ
Sbjct 541 SGLTNLRQRAEQAGGEFTLASVPGASGTVLRWSAPLSQ 578
>gi|183981532|ref|YP_001849823.1| two-component sensor histidine kinase DevS [Mycobacterium marinum
M]
gi|183174858|gb|ACC39968.1| two-component sensor histidine kinase DevS [Mycobacterium marinum
M]
Length=585
Score = 841 bits (2173), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 448/567 (80%), Positives = 507/567 (90%), Gaps = 0/567 (0%)
Query 12 GAAMRPLRHTLSQLRLHELLVEVQDRVEQIVEGRDRLDGLVEAMLVVTAGLDLEATLRAI 71
G +RPLR TLSQLRL ELLVEVQ+RVEQIVEGRDRLDGLVEAMLVVT+GL+L ATLR I
Sbjct 19 GDGLRPLRLTLSQLRLRELLVEVQERVEQIVEGRDRLDGLVEAMLVVTSGLELNATLRTI 78
Query 72 VHSATSLVDARYGAMEVHDRQHRVLHFVYEGIDEETVRRIGHLPKGLGVIGLLIEDPKPL 131
VHSAT+LVDARY A+EVHDR RVL FVYEGIDE+TV RIGHLP+GLGVIGLLI++PKPL
Sbjct 79 VHSATNLVDARYCALEVHDRDKRVLQFVYEGIDEDTVARIGHLPEGLGVIGLLIDEPKPL 138
Query 132 RLDDVSAHPASIGFPPYHPPMRTFLGVPVRVRDESFGTLYLTDKTNGQPFSDDDEVLVQA 191
RL+D+S HPASIGFP +HPPMRTFLGVPVRVRD S GTLYLTDKTNGQPFSDDDE+LVQA
Sbjct 139 RLEDISQHPASIGFPSHHPPMRTFLGVPVRVRDVSLGTLYLTDKTNGQPFSDDDELLVQA 198
Query 192 LAAAAGIAVANARLYQQAKARQSWIEATRDIATELLSGTEPATVFRLVAAEALKLTAADA 251
LAAAAGIA+ANARLY+QAKARQ+WI ATRDIATELLSGTEPA+VFRLVA EALKLT+ADA
Sbjct 199 LAAAAGIAIANARLYEQAKARQAWIGATRDIATELLSGTEPASVFRLVAEEALKLTSADA 258
Query 252 ALVAVPVDEDMPAADVGELLVIETVGSAVASIVGRTIPVAGAVLREVFVNGIPRRVDRVD 311
ALVAVPVDED+PA++V +LLVIETVG+AVA+ G TI VAG L EV ++ PR+VD++
Sbjct 259 ALVAVPVDEDVPASEVAQLLVIETVGNAVAAAEGCTIAVAGTALAEVLLDSAPRQVDKIA 318
Query 312 LEGLDELADAGPALLLPLRARGTVAGVVVVLSQGGPGAFTDEQLEMMAAFADQAALAWQL 371
+EG+DEL D GPAL+LPLRA VAGVVV+L P + T+EQLEMMAAFADQAALA QL
Sbjct 319 VEGVDELGDTGPALVLPLRATDAVAGVVVLLHPSSPESVTEEQLEMMAAFADQAALALQL 378
Query 372 ATSQRRMRELDVLTDRDRIARDLHDHVIQRLFAIGLALQGAVPHERNPEVQQRLSDVVDD 431
ATSQRRMRELDV+T+RDRIARDLHDHVIQRLFAIGLALQG+VP R P+VQQRLS+V+DD
Sbjct 379 ATSQRRMRELDVMTERDRIARDLHDHVIQRLFAIGLALQGSVPRTREPKVQQRLSEVIDD 438
Query 432 LQDVIQEIRTTIYDLHGASQGITRLRQRIDAAVAQFADSGLRTSVQFVGPLSVVDSALAD 491
LQ VIQEIRTTI+DLHG+SQG+TRLRQRIDAAVA F SGLRT+VQF+GPLSVVD+ LAD
Sbjct 439 LQGVIQEIRTTIFDLHGSSQGVTRLRQRIDAAVAAFGSSGLRTTVQFIGPLSVVDNVLAD 498
Query 492 QAEAVVREAVSNAVRHAKASTLTVRVKVDDDLCIEVTDNGRGLPDEFTGSGLTNLRQRAE 551
AEAVVREAVSNAVRHA+A+TLTVRVKVDDDLCIEV+DNGRG+P +T SGLTNLR+RA+
Sbjct 499 HAEAVVREAVSNAVRHAQATTLTVRVKVDDDLCIEVSDNGRGMPKTYTSSGLTNLRRRAQ 558
Query 552 QAGGEFTLASVPGASGTVLRWSAPLSQ 578
+AGG+FT+ S GT+LRWSAPL Q
Sbjct 559 EAGGQFTIESPAAGGGTLLRWSAPLIQ 585
>gi|118617913|ref|YP_906245.1| two component sensor histidine kinase DevS [Mycobacterium ulcerans
Agy99]
gi|118570023|gb|ABL04774.1| two component sensor histidine kinase DevS [Mycobacterium ulcerans
Agy99]
Length=585
Score = 837 bits (2163), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 445/567 (79%), Positives = 507/567 (90%), Gaps = 0/567 (0%)
Query 12 GAAMRPLRHTLSQLRLHELLVEVQDRVEQIVEGRDRLDGLVEAMLVVTAGLDLEATLRAI 71
G +RPLR TLSQLRL ELLVEVQ+RVEQIVEGRDRLDGLVEAMLVVT+GL+L+ATLR I
Sbjct 19 GDGLRPLRLTLSQLRLRELLVEVQERVEQIVEGRDRLDGLVEAMLVVTSGLELDATLRTI 78
Query 72 VHSATSLVDARYGAMEVHDRQHRVLHFVYEGIDEETVRRIGHLPKGLGVIGLLIEDPKPL 131
VHSAT+LVDARY A+EVHDR RVL FVYEGIDE+TV RIGHLP+GLG+IGLLI++PKPL
Sbjct 79 VHSATNLVDARYCALEVHDRDKRVLQFVYEGIDEDTVARIGHLPEGLGIIGLLIDEPKPL 138
Query 132 RLDDVSAHPASIGFPPYHPPMRTFLGVPVRVRDESFGTLYLTDKTNGQPFSDDDEVLVQA 191
RL+D+S HPASIGFP +HPPMRTFLGVPVRVRD S GTLYLTDKTNGQPFSDDDE+LVQA
Sbjct 139 RLEDISQHPASIGFPSHHPPMRTFLGVPVRVRDVSLGTLYLTDKTNGQPFSDDDELLVQA 198
Query 192 LAAAAGIAVANARLYQQAKARQSWIEATRDIATELLSGTEPATVFRLVAAEALKLTAADA 251
LAAAAGIA+ANARLY+QAKARQ+WI ATRDIATELLSGTEPA+VFRLVA EALKLT+ADA
Sbjct 199 LAAAAGIAIANARLYEQAKARQAWIGATRDIATELLSGTEPASVFRLVAEEALKLTSADA 258
Query 252 ALVAVPVDEDMPAADVGELLVIETVGSAVASIVGRTIPVAGAVLREVFVNGIPRRVDRVD 311
ALVA+PVDED+PA++V +LLVIETVG+AVA+ G TI VAG L EV ++ PR+VD++
Sbjct 259 ALVAIPVDEDVPASEVAQLLVIETVGNAVAAAEGCTIAVAGTALAEVLLDSAPRQVDKIA 318
Query 312 LEGLDELADAGPALLLPLRARGTVAGVVVVLSQGGPGAFTDEQLEMMAAFADQAALAWQL 371
+E +DEL D GPAL+LPLRA VAGVVV+L P + T+EQLEMMAAFADQAALA QL
Sbjct 319 VEDVDELGDMGPALVLPLRATDAVAGVVVLLHPSSPESVTEEQLEMMAAFADQAALALQL 378
Query 372 ATSQRRMRELDVLTDRDRIARDLHDHVIQRLFAIGLALQGAVPHERNPEVQQRLSDVVDD 431
ATSQRRMRELDV+T+RDRIARDLHDHVIQRLFAIGLALQG+VP R P+VQQRLS+V+DD
Sbjct 379 ATSQRRMRELDVVTERDRIARDLHDHVIQRLFAIGLALQGSVPRTREPKVQQRLSEVIDD 438
Query 432 LQDVIQEIRTTIYDLHGASQGITRLRQRIDAAVAQFADSGLRTSVQFVGPLSVVDSALAD 491
LQ VIQEIRTTI+DLHG+SQG+TRLRQRIDAAVA F SGLRT+VQF+GPLSVVD+ LAD
Sbjct 439 LQGVIQEIRTTIFDLHGSSQGVTRLRQRIDAAVAAFGSSGLRTTVQFIGPLSVVDNVLAD 498
Query 492 QAEAVVREAVSNAVRHAKASTLTVRVKVDDDLCIEVTDNGRGLPDEFTGSGLTNLRQRAE 551
AEAVVREAVSNAVRHA+A+TLTVRVKVDDDLCIEV+DNGRG+P +T SGLTNLR+RA+
Sbjct 499 HAEAVVREAVSNAVRHAQATTLTVRVKVDDDLCIEVSDNGRGMPKTYTSSGLTNLRRRAQ 558
Query 552 QAGGEFTLASVPGASGTVLRWSAPLSQ 578
+AGG+FT+ S GT+LRWSAPL Q
Sbjct 559 EAGGQFTIESPAAGGGTLLRWSAPLIQ 585
>gi|240168621|ref|ZP_04747280.1| two component sensor histidine kinase DevS [Mycobacterium kansasii
ATCC 12478]
Length=577
Score = 829 bits (2141), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 437/566 (78%), Positives = 496/566 (88%), Gaps = 4/566 (0%)
Query 13 AAMRPLRHTLSQLRLHELLVEVQDRVEQIVEGRDRLDGLVEAMLVVTAGLDLEATLRAIV 72
+ +RPLR TLSQLRL ELLVEVQ+RVEQIV+GRDRLDGLVEAMLVVT+GLDL+ TLR IV
Sbjct 16 SGLRPLRQTLSQLRLRELLVEVQERVEQIVDGRDRLDGLVEAMLVVTSGLDLDVTLRTIV 75
Query 73 HSATSLVDARYGAMEVHDRQHRVLHFVYEGIDEETVRRIGHLPKGLGVIGLLIEDPKPLR 132
HSAT+LVDARYGA+EVHDR RVL FVYEG DEETV+ IGHLP+GLG+IGLLI++PKPLR
Sbjct 76 HSATNLVDARYGALEVHDRDKRVLQFVYEGFDEETVQAIGHLPQGLGIIGLLIDEPKPLR 135
Query 133 LDDVSAHPASIGFPPYHPPMRTFLGVPVRVRDESFGTLYLTDKTNGQPFSDDDEVLVQAL 192
LDD+S HPAS+GFP HPPMRTFLGVPVRV D S GTLYLTDKTNGQPFSDDDE+LVQAL
Sbjct 136 LDDLSLHPASVGFPANHPPMRTFLGVPVRVHDMSLGTLYLTDKTNGQPFSDDDELLVQAL 195
Query 193 AAAAGIAVANARLYQQAKARQSWIEATRDIATELLSGTEPATVFRLVAAEALKLTAADAA 252
AAAAGIA+ANARLYQQA RQSWIEATRDIATELLSG EPATVFRLVA EALKLTAADAA
Sbjct 196 AAAAGIAIANARLYQQATTRQSWIEATRDIATELLSGAEPATVFRLVAEEALKLTAADAA 255
Query 253 LVAVPVDEDMPAADVGELLVIETVGSAVASIVGRTIPVAGAVLREVFVNGIPRRVDRVDL 312
LVA+P+DE++PAA+V E+LVIETVGSAVA ++G+ I + VL +V + P++V++ +L
Sbjct 256 LVAIPLDENVPAAEVTEVLVIETVGSAVAPVMGQVISLTDTVLADVCADSSPKQVEKFEL 315
Query 313 EGLDELADAGPALLLPLRARGTVAGVVVVLSQGGPGAFTDEQLEMMAAFADQAALAWQLA 372
+G+D AGPALLLPLRA T AGVVV+L G T++QLEMMAAF+DQAALA QLA
Sbjct 316 DGVDV---AGPALLLPLRATDTCAGVVVLLRHDSSGPATEDQLEMMAAFSDQAALALQLA 372
Query 373 TSQRRMRELDVLTDRDRIARDLHDHVIQRLFAIGLALQGAVPHERNPEVQQRLSDVVDDL 432
SQRRMRELDV+T+RDRIARDLHDHVIQRLFA+GLALQ AVP R PEVQQRLS+ +DDL
Sbjct 373 GSQRRMRELDVVTERDRIARDLHDHVIQRLFAVGLALQAAVPRARVPEVQQRLSEAIDDL 432
Query 433 QDVIQEIRTTIYDLHGASQGITRLRQRIDAAVAQFADSGLRTSVQFVGPLSVVDSALADQ 492
Q VIQEIRTTI+DLHG SQGITRLRQRIDAAVAQFA SGLRTSVQFVGPLSVVD+ LAD
Sbjct 433 QGVIQEIRTTIFDLHGGSQGITRLRQRIDAAVAQFAGSGLRTSVQFVGPLSVVDNLLADH 492
Query 493 AEAVVREAVSNAVRHAKASTLTVRVKVDDDLCIEVTDNGRGLPDEFTGSGLTNLRQRAEQ 552
AEA+VREAVSNAVRHA+A+TL VRVKV DDLCIEV+DNG G+PD+FT SGLTNLR+RAE+
Sbjct 493 AEAMVREAVSNAVRHARATTLMVRVKVADDLCIEVSDNGCGMPDQFTASGLTNLRRRAEE 552
Query 553 AGGEFTLASVPGASGTVLRWSAPLSQ 578
AGGEF + + + GT+LRWSAPL Q
Sbjct 553 AGGEFAIEAT-ASGGTLLRWSAPLLQ 577
>gi|118468427|ref|YP_889487.1| GAF family protein [Mycobacterium smegmatis str. MC2 155]
gi|118169714|gb|ABK70610.1| GAF family protein [Mycobacterium smegmatis str. MC2 155]
Length=571
Score = 711 bits (1836), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 375/560 (67%), Positives = 442/560 (79%), Gaps = 8/560 (1%)
Query 17 PLRHTLSQLRLHELLVEVQDRVEQIVEGRDRLDGLVEAMLVVTAGLDLEATLRAIVHSAT 76
PLR TLSQLRL ELL EVQDRVEQIVEGRDRLDGLVEAMLVVT+GL+L+ TLR IVH+A
Sbjct 18 PLRDTLSQLRLRELLSEVQDRVEQIVEGRDRLDGLVEAMLVVTSGLELDVTLRTIVHTAI 77
Query 77 SLVDARYGAMEVHDRQHRVLHFVYEGIDEETVRRIGHLPKGLGVIGLLIEDPKPLRLDDV 136
LVDARYGA+ V H ++ F+YEGI E IG LP+G GV+G+LI+DPKP+RLDD+
Sbjct 78 ELVDARYGALGVRGEDHHLIEFIYEGITPEVREEIGPLPEGRGVLGVLIDDPKPIRLDDI 137
Query 137 SAHPASIGFPPYHPPMRTFLGVPVRVRDESFGTLYLTDKTNGQPFSDDDEVLVQALAAAA 196
HPAS+GFPP HPPMRTFLGVPVR RD+ FG LYLT+KTNGQPFS+DDEVLVQALAAAA
Sbjct 138 RLHPASVGFPPNHPPMRTFLGVPVRTRDKVFGNLYLTEKTNGQPFSEDDEVLVQALAAAA 197
Query 197 GIAVANARLYQQAKARQSWIEATRDIATELLSGTEPATVFRLVAAEALKLTAADAALVAV 256
GIAV NARLY++++ARQ+WI ATRDI T+LLSGT+PATVFRLVAAEAL LT AD LVAV
Sbjct 198 GIAVDNARLYEESQARQAWIAATRDIGTQLLSGTDPATVFRLVAAEALTLTGADGTLVAV 257
Query 257 PVDEDMPAADVGELLVIETVGSAVASIVGRTIPVAGAVLREVFVNGIPRRVDRVDLEGLD 316
P D D AA+ EL+++E G+ A + IPV + + F + PRR+D +D GL
Sbjct 258 PADPDASAAE--ELVIVEVAGAVPAEVEASAIPVQDNAIGQAFRDRAPRRLDVLDGPGL- 314
Query 317 ELADAGPALLLPLRARGTVAGVVVVLSQGGPGAFTDEQLEMMAAFADQAALAWQLATSQR 376
GPAL+LPLRA TVAGV+V + G FT EQLEMM FADQAA+AWQLA+SQR
Sbjct 315 ----GGPALVLPLRATDTVAGVLVAVQGSGARPFTAEQLEMMTGFADQAAVAWQLASSQR 370
Query 377 RMRELDVLTDRDRIARDLHDHVIQRLFAIGLALQGAVPHERNPEVQQRLSDVVDDLQDVI 436
RM ELD+L DRDRIARDLHDHVIQRLFA+GL+LQG +P R+ EVQQR++D VDDLQ VI
Sbjct 371 RMSELDILADRDRIARDLHDHVIQRLFAVGLSLQGTIPRARSAEVQQRIADCVDDLQAVI 430
Query 437 QEIRTTIYDLHGASQGITRLRQRIDAAVAQFADSGLRTSVQFVGPLSVVDSALADQAEAV 496
EIRT I+DLH + G TRLRQR+D A+AQF+ +GL T+ QFVGPLSVVD+ LAD AEAV
Sbjct 431 SEIRTAIFDLHHTAPGGTRLRQRLDEAIAQFSGAGLHTTSQFVGPLSVVDAELADHAEAV 490
Query 497 VREAVSNAVRHAKASTLTVRVKVDDDLCIEVTDNGRGLPDEFTGSGLTNLRQRAEQAGGE 556
+REAVSN VRH+ A+ LTVRVKV+DDL IEVTD+G G+ T SGL+NLRQRA+Q GGE
Sbjct 491 LREAVSNVVRHSGANELTVRVKVEDDLSIEVTDDGEGISGPVTESGLSNLRQRADQCGGE 550
Query 557 FTLASVPGASGTVLRWSAPL 576
+ PG GT+LRW+APL
Sbjct 551 LRIIDRPGG-GTILRWTAPL 569
>gi|333991619|ref|YP_004524233.1| two-component sensor histidine kinase [Mycobacterium sp. JDM601]
gi|333487587|gb|AEF36979.1| two-component sensor histidine kinase DevS [Mycobacterium sp.
JDM601]
Length=569
Score = 707 bits (1824), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 399/577 (70%), Positives = 476/577 (83%), Gaps = 9/577 (1%)
Query 1 MTTGGLVDENDGAAMRPLRHTLSQLRLHELLVEVQDRVEQIVEGRDRLDGLVEAMLVVTA 60
MT G D D PLR TLSQLRL ELLV VQDRVEQIVEGRDRLDGL+ AMLVVT+
Sbjct 1 MTDDGPADGPD-----PLRDTLSQLRLRELLVGVQDRVEQIVEGRDRLDGLLAAMLVVTS 55
Query 61 GLDLEATLRAIVHSATSLVDARYGAMEVHDRQHRVLHFVYEGIDEETVRRIGHLPKGLGV 120
GL+L+ATLR+IV +AT+LVDA+YGA+EVHD R+L FV+EGID++T RIG LP+GLGV
Sbjct 56 GLELDATLRSIVQTATNLVDAKYGALEVHDNDRRMLEFVHEGIDDDTFARIGRLPEGLGV 115
Query 121 IGLLIEDPKPLRLDDVSAHPASIGFPPYHPPMRTFLGVPVRVRDESFGTLYLTDKTNGQP 180
+GLLIEDPKPLRLDD++ HP+S+GFP HP MRTFLGVPV VRDE FG LYLT+K NG P
Sbjct 116 VGLLIEDPKPLRLDDLTKHPSSVGFPSGHPTMRTFLGVPVGVRDEVFGNLYLTEKANGLP 175
Query 181 FSDDDEVLVQALAAAAGIAVANARLYQQAKARQSWIEATRDIATELLSGTEPATVFRLVA 240
FS+DDEVLVQALAAAAGIA+ANARLY QAKARQSWIE+TRDIATELLSGT+P+TVFRL+A
Sbjct 176 FSEDDEVLVQALAAAAGIAIANARLYAQAKARQSWIESTRDIATELLSGTDPSTVFRLIA 235
Query 241 AEALKLTAADAALVAVPVDEDMPAADVGELLVIETVGSAVASIVGRTIPVAGAVLREVFV 300
EA KLT +++ALVA+P+D+D A+V ELLV+ET+G+ +A + G TIPVAG+ + E F
Sbjct 236 EEAGKLTGSESALVAIPLDDDTLEAEVNELLVVETIGAVMAPLDGDTIPVAGSSVGEAFS 295
Query 301 NGIPRRVDRVDLEGLDELADAGPALLLPLRARGTVAGVVVVLSQGGPGAFTDEQLEMMAA 360
PR+V R+ L G+D GPAL+LPLRA VAGVVVV+ G F+ EQL+MMAA
Sbjct 296 QRKPRQVARLALPGIDA---TGPALILPLRAADAVAGVVVVMRHGTTIPFSVEQLDMMAA 352
Query 361 FADQAALAWQLATSQRRMRELDVLTDRDRIARDLHDHVIQRLFAIGLALQGAVPHERNPE 420
FADQAALAWQLATSQRRM ELDVLTDRDRIARDLHDHVIQRLFA+GL+LQG +P R+
Sbjct 353 FADQAALAWQLATSQRRMHELDVLTDRDRIARDLHDHVIQRLFAVGLSLQGTIPRARDAV 412
Query 421 VQQRLSDVVDDLQDVIQEIRTTIYDLHGASQGITRLRQRIDAAVAQFADSGLRTSVQFVG 480
V++RL+D VDD+Q++I EIRTTI+DLHG S +TRLRQR+D AVAQF+ SGL T+V F+G
Sbjct 413 VRRRLTDAVDDMQEIIGEIRTTIFDLHGTSATVTRLRQRLDNAVAQFSGSGLHTTVAFIG 472
Query 481 PLSVVDSALADQAEAVVREAVSNAVRHAKASTLTVRVKVDDDLCIEVTDNGRGLPDEFTG 540
PLSVV+ LAD AEAVV EAVSNAVRH++A+ LTV++KV+DDL IEV DNGRG+P+ T
Sbjct 473 PLSVVEPVLADHAEAVVSEAVSNAVRHSRATELTVQIKVEDDLAIEVADNGRGMPEVVTP 532
Query 541 SGLTNLRQRAEQAGGEFTLASVPGASGTVLRWSAPLS 577
SGL NLR+RAEQAGG F + + PG GTV+RWSAPL+
Sbjct 533 SGLANLRRRAEQAGGTFGIEAAPGG-GTVVRWSAPLT 568
>gi|120402406|ref|YP_952235.1| GAF sensor signal transduction histidine kinase [Mycobacterium
vanbaalenii PYR-1]
gi|119955224|gb|ABM12229.1| GAF sensor signal transduction histidine kinase [Mycobacterium
vanbaalenii PYR-1]
Length=559
Score = 675 bits (1741), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 366/562 (66%), Positives = 434/562 (78%), Gaps = 4/562 (0%)
Query 15 MRPLRHTLSQLRLHELLVEVQDRVEQIVEGRDRLDGLVEAMLVVTAGLDLEATLRAIVHS 74
MRPLR TLSQLRL ELL EVQDRVEQIVEGRDRLDGL++AMLVVT+GL+L+ TLR IV +
Sbjct 1 MRPLRDTLSQLRLRELLNEVQDRVEQIVEGRDRLDGLLDAMLVVTSGLELDETLRTIVRT 60
Query 75 ATSLVDARYGAMEVHDRQHRVLHFVYEGIDEETVRRIGHLPKGLGVIGLLIEDPKPLRLD 134
A LVDA+YGA+ V H ++ F+Y+GIDE++ IGHLP+G GV+G+LI+DPKP+RLD
Sbjct 61 AIDLVDAQYGALGVRGHDHELVEFIYQGIDEQSKELIGHLPEGRGVLGVLIDDPKPIRLD 120
Query 135 DVSAHPASIGFPPYHPPMRTFLGVPVRVRDESFGTLYLTDKTNGQPFSDDDEVLVQALAA 194
+S HPAS+GFPP HPPMRTFLGVPVR+RDE FG LYLT+K +GQPFS+DDEVLVQALAA
Sbjct 121 RISQHPASVGFPPNHPPMRTFLGVPVRIRDEVFGNLYLTEKADGQPFSEDDEVLVQALAA 180
Query 195 AAGIAVANARLYQQAKARQSWIEATRDIATELLSGTEPATVFRLVAAEALKLTAADAALV 254
AAGIA+ NARLYQQ+K R+SWIEATRDI TE+LSG +P+ VFRLVA ++ L+ A + LV
Sbjct 181 AAGIAIENARLYQQSKTRRSWIEATRDIGTEMLSGADPSKVFRLVADQSRLLSGAQSTLV 240
Query 255 AVPVDEDMPAADVGELLVIETVGSAVASIVGRTIPVAGAVLREVFVNGIPRRVDRVDLEG 314
AV D D V EL+V+ T G + IP G+ + EVF P R D ++LE
Sbjct 241 AVRSDLDELDGRVDELVVVATAGDG-PGVSLSAIPTHGSAIGEVFSTKTPVRFDTLELEP 299
Query 315 LDELADAGPALLLPLRARGTVAGVVVVLSQGGPGAFTDEQLEMMAAFADQAALAWQLATS 374
LA GPAL+LPLRA TVAGV+V L G F E+L+MMAAF DQAALAWQLAT+
Sbjct 300 -RHLA-PGPALVLPLRATDTVAGVLVALRPEGAPPFNAEELDMMAAFVDQAALAWQLATT 357
Query 375 QRRMRELDVLTDRDRIARDLHDHVIQRLFAIGLALQGAVPHERNPEVQQRLSDVVDDLQD 434
QR++RELDVLTDRDRIARDLHDHVIQRLFA+GLALQG +P R PEV++RL+D VDDLQ
Sbjct 358 QRQLRELDVLTDRDRIARDLHDHVIQRLFAVGLALQGTIPRARAPEVRERLTDCVDDLQQ 417
Query 435 VIQEIRTTIYDLHGASQGITRLRQRIDAAVAQFADSGLRTSVQFVGPLSVVDSALADQAE 494
VIQEIRT I+DLHG G RLRQR+D A+AQF S + T+VQF GPLSVVD AL+D AE
Sbjct 418 VIQEIRTAIFDLHGGHGGSNRLRQRLDEAIAQFTASDVHTTVQFSGPLSVVDPALSDHAE 477
Query 495 AVVREAVSNAVRHAKASTLTVRVKVDDDLCIEVTDNGRGLPDEFTGSGLTNLRQRAEQAG 554
AVVREAVSNA+RH+ A+TL V V D+L IEV D+G G+P + T SGLTNLRQRA G
Sbjct 478 AVVREAVSNAIRHSGATTLDVSVTAADELIIEVADDGCGMPADVTESGLTNLRQRAGDVG 537
Query 555 GEFTLASVPGASGTVLRWSAPL 576
G FT+ S A GT LRW APL
Sbjct 538 GTFTVES-GDAGGTRLRWCAPL 558
>gi|108801089|ref|YP_641286.1| putative signal transduction histidine kinase [Mycobacterium
sp. MCS]
gi|119870230|ref|YP_940182.1| GAF sensor signal transduction histidine kinase [Mycobacterium
sp. KMS]
gi|108771508|gb|ABG10230.1| putative signal transduction histidine kinase [Mycobacterium
sp. MCS]
gi|119696319|gb|ABL93392.1| GAF sensor signal transduction histidine kinase [Mycobacterium
sp. KMS]
Length=568
Score = 671 bits (1731), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 365/561 (66%), Positives = 431/561 (77%), Gaps = 7/561 (1%)
Query 17 PLRHTLSQLRLHELLVEVQDRVEQIVEGRDRLDGLVEAMLVVTAGLDLEATLRAIVHSAT 76
PLR TLS LRL ELL EVQDR+E IVEGRDRLDGLV+AMLVVTAGL+L+ TLR IVH+A
Sbjct 15 PLRDTLSGLRLRELLTEVQDRIEMIVEGRDRLDGLVDAMLVVTAGLELDVTLRTIVHTAI 74
Query 77 SLVDARYGAMEVHDRQHRVLHFVYEGIDEETVRRIGHLPKGLGVIGLLIEDPKPLRLDDV 136
LVDARYGA+ V H ++ F+YEGID+ T IGHLP+G GV+G+LI+DP+P+RLDD+
Sbjct 75 QLVDARYGALGVRGHGHDLVQFIYEGIDDGTRDLIGHLPEGRGVLGVLIDDPRPIRLDDI 134
Query 137 SAHPASIGFPPYHPPMRTFLGVPVRVRDESFGTLYLTDKTNGQPFSDDDEVLVQALAAAA 196
H AS+GFP HPPMRTFLGVPVR+RDE +G LYLTDK GQPF+++DEVLVQALAAAA
Sbjct 135 RHHSASVGFPANHPPMRTFLGVPVRIRDEVYGNLYLTDKVGGQPFTEEDEVLVQALAAAA 194
Query 197 GIAVANARLYQQAKARQSWIEATRDIATELLSGTEPATVFRLVAAEALKLTAADAALVAV 256
GIA+ NARLY+QA+ARQ+WI ATRDIATE+LSG PATVFR V +AL LT AD LVAV
Sbjct 195 GIAIDNARLYEQARARQAWIAATRDIATEMLSGASPATVFRRVVDQALTLTGADGTLVAV 254
Query 257 PVDEDMPAADVGELLVIETVGSAVASIVGRTIPVAGAVLREVFVNGIPRRVDRVDLEGLD 316
P D + P V +L+V+E+ G + V T+ + + + F P RVDR+ L
Sbjct 255 PGDTEAPPDQVHDLVVVESAGMFTGAAV--TVALDESPIGLAFRKRTPVRVDRLTLGS-- 310
Query 317 ELADAGPALLLPLRARGTVAGVVVVLSQGGPGAFTDEQLEMMAAFADQAALAWQLATSQR 376
A+ G AL+LPLRA TVAGV+V G FT EQL++ AAFADQ ALAWQLA+SQR
Sbjct 311 --AECGAALVLPLRAADTVAGVLVAARVPGAQEFTAEQLDVTAAFADQMALAWQLASSQR 368
Query 377 RMRELDVLTDRDRIARDLHDHVIQRLFAIGLALQGAVPHERNPEVQQRLSDVVDDLQDVI 436
RM+EL++LTDRDRIARDLHDHVIQRLFA+GL+LQG + R+ +VQQRL+ VDDLQ VI
Sbjct 369 RMQELEILTDRDRIARDLHDHVIQRLFAVGLSLQGTLARVRDADVQQRLAGNVDDLQAVI 428
Query 437 QEIRTTIYDLHGASQGITRLRQRIDAAVAQFADSGLRTSVQFVGPLSVVDSALADQAEAV 496
QEIRTTI+DLHG S G TRLRQR+D A+ QFA +GL T+ QFVGPLSVVD+ LAD AEAV
Sbjct 429 QEIRTTIFDLHGGSSGATRLRQRLDEAIGQFAGAGLHTTAQFVGPLSVVDATLADHAEAV 488
Query 497 VREAVSNAVRHAKASTLTVRVKVDDDLCIEVTDNGRGLPDEFTGSGLTNLRQRAEQAGGE 556
VREAVSNAVRHA+A+ LTVRV V DDLCIEV DNG G+ T SGL NLR RAE AGG
Sbjct 489 VREAVSNAVRHARATELTVRVTVADDLCIEVADNGCGIDGSITESGLGNLRARAEDAGGT 548
Query 557 FTLASVPGASGTVLRWSAPLS 577
TL G GT+LRW APL+
Sbjct 549 LTLGESAGG-GTLLRWCAPLA 568
>gi|108798050|ref|YP_638247.1| GAF sensor signal transduction histidine kinase [Mycobacterium
sp. MCS]
gi|119867145|ref|YP_937097.1| GAF sensor signal transduction histidine kinase [Mycobacterium
sp. KMS]
gi|126433710|ref|YP_001069401.1| GAF sensor signal transduction histidine kinase [Mycobacterium
sp. JLS]
gi|108768469|gb|ABG07191.1| GAF sensor signal transduction histidine kinase [Mycobacterium
sp. MCS]
gi|119693234|gb|ABL90307.1| GAF sensor signal transduction histidine kinase [Mycobacterium
sp. KMS]
gi|126233510|gb|ABN96910.1| GAF sensor signal transduction histidine kinase [Mycobacterium
sp. JLS]
Length=566
Score = 668 bits (1723), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 361/573 (64%), Positives = 439/573 (77%), Gaps = 12/573 (2%)
Query 7 VDENDGAAMRPLRHTLSQLRLHELLVEVQDRVEQIVEGRDRLDGLVEAMLVVTAGLDLEA 66
V D ++RP+ TLSQLRL ELL EVQDRVE+IVEGRDRLDGLV+AML VT+GLDL+A
Sbjct 4 VGPGDQCSVRPIGETLSQLRLRELLTEVQDRVEEIVEGRDRLDGLVDAMLTVTSGLDLDA 63
Query 67 TLRAIVHSATSLVDARYGAMEVHDRQHRVLHFVYEGIDEETVRRIGHLPKGLGVIGLLIE 126
TLR IVH+A L+DARYGA+ V H ++ F+YEGIDE T IG LP+G GV+G+LI+
Sbjct 64 TLRTIVHTAIELIDARYGALGVRGHDHELVEFIYEGIDEPTRLAIGPLPQGRGVLGVLID 123
Query 127 DPKPLRLDDVSAHPASIGFPPYHPPMRTFLGVPVRVRDESFGTLYLTDKTNGQPFSDDDE 186
DP+P+RL+++ HPAS+GFP +HPPMRTFLGVP+R+RDE FG LYL++KT+GQPFS+DDE
Sbjct 124 DPQPIRLENIHDHPASVGFPEHHPPMRTFLGVPIRIRDEVFGNLYLSEKTSGQPFSEDDE 183
Query 187 VLVQALAAAAGIAVANARLYQQAKARQSWIEATRDIATELLSGTEPATVFRLVAAEALKL 246
VL QALAAAAGIA+ NARL++Q++ RQ+WIEATRDIATELL G +PA V+RLVA E+LKL
Sbjct 184 VLTQALAAAAGIAIDNARLFEQSRTRQAWIEATRDIATELLGGADPARVYRLVAEESLKL 243
Query 247 TAADAALVAVPVDEDMPAADVGELLVIETVG-SAVASIVGRTIPVAGAVLREVFVNGIPR 305
T AD A VAVP D D EL++ + G + V IP+ G + E FV PR
Sbjct 244 THADVAFVAVPADGD-------ELVIADAAGDTRTDPSVASLIPLQGNDIGEAFVARTPR 296
Query 306 RVDRVDLE-GLDELADAGPALLLPLRARGTVAGVVVVLSQGGPGAFTDEQLEMMAAFADQ 364
V+ + + GL L DAGPAL+LP+R VAGVVV+L + G AFT EQLEMMAAF DQ
Sbjct 297 LVEVIAAQTGL--LDDAGPALILPMRTTEAVAGVVVLLRRAGRPAFTAEQLEMMAAFVDQ 354
Query 365 AALAWQLATSQRRMRELDVLTDRDRIARDLHDHVIQRLFAIGLALQGAVPHERNPEVQQR 424
AALAWQ A +QRR+RELDVLTDRDRIARDLHD VIQRLF +GL LQG +P R P+VQ+R
Sbjct 355 AALAWQSAVAQRRIRELDVLTDRDRIARDLHDQVIQRLFGVGLTLQGTIPRARTPDVQRR 414
Query 425 LSDVVDDLQDVIQEIRTTIYDLHGASQGITRLRQRIDAAVAQFADSGLRTSVQFVGPLSV 484
L + VDDLQ+VIQ+IRT I+DL G S G TRLRQR+D A+A A + LRT+VQ+VGPLSV
Sbjct 415 LIESVDDLQEVIQQIRTAIFDLQGGSSGSTRLRQRLDEAIAHLAGAELRTTVQYVGPLSV 474
Query 485 VDSALADQAEAVVREAVSNAVRHAKASTLTVRVKVDDDLCIEVTDNGRGLPDEFTGSGLT 544
V + LAD AEAVV EAVSNAVRHA+A+ L+V V VDDDL IE+ DNG G+PD T SGL
Sbjct 475 VGAELADHAEAVVSEAVSNAVRHAQATELSVLVTVDDDLRIEIRDNGVGIPDNLTESGLA 534
Query 545 NLRQRAEQAGGEFTLASVPGASGTVLRWSAPLS 577
NLR+RAE+ GG T+ G GT L W+APL+
Sbjct 535 NLRRRAEEVGGALTIEPAAGG-GTCLSWTAPLT 566
>gi|126436927|ref|YP_001072618.1| GAF sensor signal transduction histidine kinase [Mycobacterium
sp. JLS]
gi|126236727|gb|ABO00128.1| GAF sensor signal transduction histidine kinase [Mycobacterium
sp. JLS]
Length=568
Score = 668 bits (1723), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 364/561 (65%), Positives = 430/561 (77%), Gaps = 7/561 (1%)
Query 17 PLRHTLSQLRLHELLVEVQDRVEQIVEGRDRLDGLVEAMLVVTAGLDLEATLRAIVHSAT 76
PLR TLS LRL ELL EVQDR+E IVEGRDRLDGLV+AMLVVTAGL+L+ TLR IVH+A
Sbjct 15 PLRDTLSGLRLRELLTEVQDRIEMIVEGRDRLDGLVDAMLVVTAGLELDVTLRTIVHTAI 74
Query 77 SLVDARYGAMEVHDRQHRVLHFVYEGIDEETVRRIGHLPKGLGVIGLLIEDPKPLRLDDV 136
LVDARYGA+ V H ++ F+YEGID+ T IGHLP+G GV+G+LI+DP+P+RLDD+
Sbjct 75 QLVDARYGALGVRGHGHDLVQFIYEGIDDGTRDLIGHLPEGRGVLGVLIDDPRPIRLDDI 134
Query 137 SAHPASIGFPPYHPPMRTFLGVPVRVRDESFGTLYLTDKTNGQPFSDDDEVLVQALAAAA 196
H AS+GFP HPPMRTFLGVPVR+RDE +G LYLTDK GQPF+++DEVLVQALAAAA
Sbjct 135 RHHSASVGFPANHPPMRTFLGVPVRIRDEVYGNLYLTDKVGGQPFTEEDEVLVQALAAAA 194
Query 197 GIAVANARLYQQAKARQSWIEATRDIATELLSGTEPATVFRLVAAEALKLTAADAALVAV 256
GIA+ NARLY+QA+ARQ+WI ATRDIATE+LSG PATVFR V +AL LT AD LVAV
Sbjct 195 GIAIDNARLYEQARARQAWIAATRDIATEMLSGASPATVFRRVVDQALTLTGADGTLVAV 254
Query 257 PVDEDMPAADVGELLVIETVGSAVASIVGRTIPVAGAVLREVFVNGIPRRVDRVDLEGLD 316
P D + P V +L+V+E+ G + V T+ + + + F P RVDR+ L
Sbjct 255 PGDTEAPPDQVHDLVVVESAGMFTGAAV--TVALDESPIGLAFRKRTPVRVDRLTLGS-- 310
Query 317 ELADAGPALLLPLRARGTVAGVVVVLSQGGPGAFTDEQLEMMAAFADQAALAWQLATSQR 376
A+ G AL+LPLRA TVAGV+V G FT EQL++ AAFADQ ALAWQLA+SQR
Sbjct 311 --AECGAALVLPLRAADTVAGVLVAARVPGAQGFTAEQLDVTAAFADQMALAWQLASSQR 368
Query 377 RMRELDVLTDRDRIARDLHDHVIQRLFAIGLALQGAVPHERNPEVQQRLSDVVDDLQDVI 436
RM+EL++LTDRDRIARDLHDHVIQRLFA+GL+LQG + R+ +VQQRL+ VDDLQ VI
Sbjct 369 RMQELEILTDRDRIARDLHDHVIQRLFAVGLSLQGTLARVRDADVQQRLAGNVDDLQAVI 428
Query 437 QEIRTTIYDLHGASQGITRLRQRIDAAVAQFADSGLRTSVQFVGPLSVVDSALADQAEAV 496
QEIRTTI+DLHG S G TRLRQR+D A+ QFA + L T+ QFVGPLSVVD+ LAD AEAV
Sbjct 429 QEIRTTIFDLHGGSSGATRLRQRLDEAIGQFAGARLHTTAQFVGPLSVVDATLADHAEAV 488
Query 497 VREAVSNAVRHAKASTLTVRVKVDDDLCIEVTDNGRGLPDEFTGSGLTNLRQRAEQAGGE 556
VREAVSNAVRHA+A+ LTVRV V DDLCIEV DNG G+ T SGL NLR RAE AGG
Sbjct 489 VREAVSNAVRHARATELTVRVTVADDLCIEVADNGCGIDGSITESGLGNLRARAEDAGGT 548
Query 557 FTLASVPGASGTVLRWSAPLS 577
TL G GT+LRW APL+
Sbjct 549 LTLGESAGG-GTLLRWCAPLA 568
>gi|315444759|ref|YP_004077638.1| histidine kinase with GAF domain [Mycobacterium sp. Spyr1]
gi|315263062|gb|ADT99803.1| histidine kinase with GAF domain [Mycobacterium sp. Spyr1]
Length=575
Score = 645 bits (1663), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 370/580 (64%), Positives = 442/580 (77%), Gaps = 10/580 (1%)
Query 1 MTTGGLVDENDGAA---MRPLRHTLSQLRLHELLVEVQDRVEQIVEGRDRLDGLVEAMLV 57
M G + D +D A RP+R TLSQLRL ELL EVQDRVEQI+ GRDRLDGLVEAML
Sbjct 1 MHDGAVADADDHRARDGARPVRTTLSQLRLRELLTEVQDRVEQIIRGRDRLDGLVEAMLA 60
Query 58 VTAGLDLEATLRAIVHSATSLVDARYGAMEVHDRQHRVLHFVYEGIDEETVRRIGHLPKG 117
VT+GL+L+ TLR IVH+A LVDA+YGA+ V ++ F+YEGIDE RIGHLP+G
Sbjct 61 VTSGLELDETLRTIVHTAIELVDAQYGALGVRGHDQELVEFIYEGIDEPMRERIGHLPEG 120
Query 118 LGVIGLLIEDPKPLRLDDVSAHPASIGFPPYHPPMRTFLGVPVRVRDESFGTLYLTDKTN 177
GV+G+LI DPKP+RL+D+S H S+GFPP HPPMRTFLGVPVR+RDE FG LYLT+K++
Sbjct 121 RGVLGVLINDPKPIRLEDISRHADSVGFPPNHPPMRTFLGVPVRIRDEVFGNLYLTEKSD 180
Query 178 GQPFSDDDEVLVQALAAAAGIAVANARLYQQAKARQSWIEATRDIATELLSGTEPATVFR 237
GQPFS+DDEVLVQALAAAAGIA+ NARLY Q++ARQSWIEATRDI TELLSG +PA VFR
Sbjct 181 GQPFSEDDEVLVQALAAAAGIAIDNARLYAQSQARQSWIEATRDIGTELLSGIDPAGVFR 240
Query 238 LVAAEALKLTAADAALVAVPVDEDMPAADVGELLVIETVGSAVASIVGRTIPVAGAVLRE 297
VA A KL+ A A LVAVP D D+P +V EL V + G +A+ IPVAG + +
Sbjct 241 RVADRAQKLSGAAATLVAVPDDPDLPVGEVAELTVAASAGETIAA-AHDPIPVAGTAIGD 299
Query 298 VFVNGIPRRVDRVDLEGLDELADAGPALLLPLRARGTVAGVVVVLSQGGPGAFTDEQLEM 357
FV+ P DR D+ G+ A GPALLLPLRA V GV++VL G F ++L+M
Sbjct 300 AFVHRTPGMTDRADI-GIG--ATVGPALLLPLRAPDAVPGVLIVLRSVGAQPFRSDELDM 356
Query 358 MAAFADQAALAWQLATSQRRMRELDVLTDRDRIARDLHDHVIQRLFAIGLALQGAVPHER 417
+AAFADQAA AWQLA++Q R+REL +LTDRDRIARDLHDHVIQRLFA+GL+LQG++ R
Sbjct 357 LAAFADQAAQAWQLASTQHRLRELGILTDRDRIARDLHDHVIQRLFAVGLSLQGSIARSR 416
Query 418 NPEVQQRLSDVVDDLQDVIQEIRTTIYDLHGASQGITRLRQRIDAAVAQFADSGLRTSVQ 477
+ EVQQRLS VDDLQ VIQEIRT I+DLHG S +TRLRQR+DAAVA F +SG+RTS+Q
Sbjct 417 SEEVQQRLSANVDDLQSVIQEIRTAIFDLHGGSSAVTRLRQRLDAAVAAFPESGVRTSMQ 476
Query 478 FVGPLSVVDSALADQAEAVVREAVSNAVRHAKASTLTVRVKVDDDLCIEVTDNGRGLPDE 537
GPLSVVD+ LAD AEAVVREAVSNAVRHA+AST+ V V V+DDL I VTD+GRG+ +
Sbjct 477 CAGPLSVVDAGLADHAEAVVREAVSNAVRHAEASTVAVTVTVEDDLAITVTDDGRGIAAD 536
Query 538 FTGSGLTNLRQRAEQAGGEFTLASVPGAS-GTVLRWSAPL 576
TGSGL NL +RA+ GG F++ GA GT L W APL
Sbjct 537 VTGSGLANLARRAQDVGGSFSVRR--GAQVGTTLTWRAPL 574
>gi|145224426|ref|YP_001135104.1| GAF sensor signal transduction histidine kinase [Mycobacterium
gilvum PYR-GCK]
gi|145216912|gb|ABP46316.1| GAF sensor signal transduction histidine kinase [Mycobacterium
gilvum PYR-GCK]
Length=575
Score = 645 bits (1663), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 370/580 (64%), Positives = 442/580 (77%), Gaps = 10/580 (1%)
Query 1 MTTGGLVDENDGAA---MRPLRHTLSQLRLHELLVEVQDRVEQIVEGRDRLDGLVEAMLV 57
M G + D +D A RP+R TLSQLRL ELL EVQDRVEQI+ GRDRLDGLVEAML
Sbjct 1 MHDGAVADADDHRARDGARPVRTTLSQLRLRELLTEVQDRVEQIIRGRDRLDGLVEAMLA 60
Query 58 VTAGLDLEATLRAIVHSATSLVDARYGAMEVHDRQHRVLHFVYEGIDEETVRRIGHLPKG 117
VT+GL+L+ TLR IVH+A LVDA+YGA+ V ++ F+YEGIDE RIGHLP+G
Sbjct 61 VTSGLELDETLRTIVHTAIELVDAQYGALGVRGHDQELVEFIYEGIDEPMRERIGHLPEG 120
Query 118 LGVIGLLIEDPKPLRLDDVSAHPASIGFPPYHPPMRTFLGVPVRVRDESFGTLYLTDKTN 177
GV+G+LI DPKP+RL+D+S H S+GFPP HPPMRTFLGVPVR+RDE FG LYLT+K++
Sbjct 121 RGVLGVLINDPKPIRLEDISRHADSVGFPPNHPPMRTFLGVPVRIRDEVFGNLYLTEKSD 180
Query 178 GQPFSDDDEVLVQALAAAAGIAVANARLYQQAKARQSWIEATRDIATELLSGTEPATVFR 237
GQPFS+DDEVLVQALAAAAGIA+ NARLY Q++ARQSWIEATRDI TELLSG +PA VFR
Sbjct 181 GQPFSEDDEVLVQALAAAAGIAIDNARLYAQSQARQSWIEATRDIGTELLSGIDPAGVFR 240
Query 238 LVAAEALKLTAADAALVAVPVDEDMPAADVGELLVIETVGSAVASIVGRTIPVAGAVLRE 297
VA A KL+ A A LVAVP D D+P +V EL V + G +A+ IPVAG + +
Sbjct 241 RVADRAQKLSGAAATLVAVPDDPDLPVGEVAELTVAASAGETIAA-AHDPIPVAGTAIGD 299
Query 298 VFVNGIPRRVDRVDLEGLDELADAGPALLLPLRARGTVAGVVVVLSQGGPGAFTDEQLEM 357
FV+ P DR D+ G+ A GPALLLPLRA V GV++VL G F ++L+M
Sbjct 300 AFVHRTPGMTDRADI-GIG--ATVGPALLLPLRAPDAVPGVLIVLRSVGAQPFRSDELDM 356
Query 358 MAAFADQAALAWQLATSQRRMRELDVLTDRDRIARDLHDHVIQRLFAIGLALQGAVPHER 417
+AAFADQAA AWQLA++Q R+REL +LTDRDRIARDLHDHVIQRLFA+GL+LQG++ R
Sbjct 357 LAAFADQAAQAWQLASTQHRLRELGILTDRDRIARDLHDHVIQRLFAVGLSLQGSIARAR 416
Query 418 NPEVQQRLSDVVDDLQDVIQEIRTTIYDLHGASQGITRLRQRIDAAVAQFADSGLRTSVQ 477
+ EVQQRLS VDDLQ VIQEIRT I+DLHG S +TRLRQR+DAAVA F +SG+RTS+Q
Sbjct 417 SEEVQQRLSANVDDLQSVIQEIRTAIFDLHGGSSAVTRLRQRLDAAVAAFPESGVRTSMQ 476
Query 478 FVGPLSVVDSALADQAEAVVREAVSNAVRHAKASTLTVRVKVDDDLCIEVTDNGRGLPDE 537
GPLSVVD+ LAD AEAVVREAVSNAVRHA+AST+ V V V+DDL I VTD+GRG+ +
Sbjct 477 CAGPLSVVDAGLADHAEAVVREAVSNAVRHAEASTVAVTVTVEDDLAITVTDDGRGIAAD 536
Query 538 FTGSGLTNLRQRAEQAGGEFTLASVPGAS-GTVLRWSAPL 576
TGSGL NL +RA+ GG F++ GA GT L W APL
Sbjct 537 VTGSGLANLARRAQDVGGSFSVRR--GAQVGTTLTWRAPL 574
>gi|15609164|ref|NP_216543.1| histidine kinase response regulator [Mycobacterium tuberculosis
H37Rv]
gi|15841514|ref|NP_336551.1| GAF family protein [Mycobacterium tuberculosis CDC1551]
gi|148661841|ref|YP_001283364.1| histidine kinase response regulator [Mycobacterium tuberculosis
H37Ra]
53 more sequence titles
Length=573
Score = 626 bits (1614), Expect = 4e-177, Method: Compositional matrix adjust.
Identities = 350/560 (63%), Positives = 442/560 (79%), Gaps = 2/560 (0%)
Query 17 PLRHTLSQLRLHELLVEVQDRVEQIVEGRDRLDGLVEAMLVVTAGLDLEATLRAIVHSAT 76
PLR TLSQLRL ELL+EVQDR+EQIVEGRDRLDGL++A+L +T+GL L+ATLRAIVH+A
Sbjct 15 PLRETLSQLRLRELLLEVQDRIEQIVEGRDRLDGLIDAILAITSGLKLDATLRAIVHTAA 74
Query 77 SLVDARYGAMEVHDRQHRVLHFVYEGIDEETVRRIGHLPKGLGVIGLLIEDPKPLRLDDV 136
LVDARYGA+ V HR++ FVYEGIDEET IG LP+G GV+G LIE+PKP+RLDD+
Sbjct 75 ELVDARYGALGVRGYDHRLVEFVYEGIDEETRHLIGSLPEGRGVLGALIEEPKPIRLDDI 134
Query 137 SAHPASIGFPPYHPPMRTFLGVPVRVRDESFGTLYLTDKTNGQPFSDDDEVLVQALAAAA 196
S HPAS+GFP +HPPMRTFLGVPVR+RDE FG LYLT+K +GQPFSDDDEVLVQALAAAA
Sbjct 135 SRHPASVGFPLHHPPMRTFLGVPVRIRDEVFGNLYLTEKADGQPFSDDDEVLVQALAAAA 194
Query 197 GIAVANARLYQQAKARQSWIEATRDIATELLSGTEPATVFRLVAAEALKLTAADAALVAV 256
GIAV NARL+++++ R++WIEATRDI T++L+G +PA VFRL+A EAL L A A LVAV
Sbjct 195 GIAVDNARLFEESRTREAWIEATRDIGTQMLAGADPAMVFRLIAEEALTLMAGAATLVAV 254
Query 257 PVDEDMPAADVGELLVIETVGSAVASIVGRTIPVAGAVLREVFVNGIPRRVDRVDLEGLD 316
P+D++ PA +V +L+++E G ++ T+ V+G + VF + PRR DR+DL +D
Sbjct 255 PLDDEAPACEVDDLVIVEVAGEISPAVKQMTVAVSGTSIGGVFHDRTPRRFDRLDL-AVD 313
Query 317 ELADAGPALLLPLRARGTVAGVVVVLSQGGPGAFTDEQLEMMAAFADQAALAWQLATSQR 376
+ GPAL+LPLRA TVAGV+V L F+D+QL+MMAAFADQAALAW+LAT+QR
Sbjct 314 GPVEPGPALVLPLRAADTVAGVLVALRSADEQPFSDKQLDMMAAFADQAALAWRLATAQR 373
Query 377 RMRELDVLTDRDRIARDLHDHVIQRLFAIGLALQGAVPHERNPEVQQRLSDVVDDLQDVI 436
+MRE+++LTDRDRIARDLHDHVIQRLFA+GL LQGA P R P V++ + +DDLQ++I
Sbjct 374 QMREVEILTDRDRIARDLHDHVIQRLFAVGLTLQGAAPRARVPAVRESIYSSIDDLQEII 433
Query 437 QEIRTTIYDLHGASQGITRLRQRIDAAVAQFADSGLRTSVQFVGPLSVVDSALADQAEAV 496
QEIR+ I+DLH T LR R+D + Q A L T+VQ+ GPLSVVD+ LA+ AEAV
Sbjct 434 QEIRSAIFDLHAGPSRATGLRHRLDKVIDQLAIPALHTTVQYTGPLSVVDTVLANHAEAV 493
Query 497 VREAVSNAVRHAKASTLTVRVKVDDDLCIEVTDNGRGLPDEFTGSGLTNLRQRAEQAGGE 556
+REAVSNAVRHA A++L + V V+DD+ +EV D+G G+ + T SGL NLRQRA+ AGGE
Sbjct 494 LREAVSNAVRHANATSLAINVSVEDDVRVEVVDDGVGISGDITESGLRNLRQRADDAGGE 553
Query 557 FTLASVPGASGTVLRWSAPL 576
FT+ ++P GT+LRWSAPL
Sbjct 554 FTVENMP-TGGTLLRWSAPL 572
>gi|31793209|ref|NP_855702.1| histidine kinase response regulator [Mycobacterium bovis AF2122/97]
gi|121637913|ref|YP_978136.1| histidine kinase response regulator [Mycobacterium bovis BCG
str. Pasteur 1173P2]
gi|224990407|ref|YP_002645094.1| histidine kinase response regulator [Mycobacterium bovis BCG
str. Tokyo 172]
8 more sequence titles
Length=573
Score = 624 bits (1610), Expect = 1e-176, Method: Compositional matrix adjust.
Identities = 349/560 (63%), Positives = 442/560 (79%), Gaps = 2/560 (0%)
Query 17 PLRHTLSQLRLHELLVEVQDRVEQIVEGRDRLDGLVEAMLVVTAGLDLEATLRAIVHSAT 76
P+R TLSQLRL ELL+EVQDR+EQIVEGRDRLDGL++A+L +T+GL L+ATLRAIVH+A
Sbjct 15 PVRETLSQLRLRELLLEVQDRIEQIVEGRDRLDGLIDAILAITSGLKLDATLRAIVHTAA 74
Query 77 SLVDARYGAMEVHDRQHRVLHFVYEGIDEETVRRIGHLPKGLGVIGLLIEDPKPLRLDDV 136
LVDARYGA+ V HR++ FVYEGIDEET IG LP+G GV+G LIE+PKP+RLDD+
Sbjct 75 ELVDARYGALGVRGYDHRLVEFVYEGIDEETRHLIGSLPEGRGVLGALIEEPKPIRLDDI 134
Query 137 SAHPASIGFPPYHPPMRTFLGVPVRVRDESFGTLYLTDKTNGQPFSDDDEVLVQALAAAA 196
S HPAS+GFP +HPPMRTFLGVPVR+RDE FG LYLT+K +GQPFSDDDEVLVQALAAAA
Sbjct 135 SRHPASVGFPLHHPPMRTFLGVPVRIRDEVFGNLYLTEKADGQPFSDDDEVLVQALAAAA 194
Query 197 GIAVANARLYQQAKARQSWIEATRDIATELLSGTEPATVFRLVAAEALKLTAADAALVAV 256
GIAV NARL+++++ R++WIEATRDI T++L+G +PA VFRL+A EAL L A A LVAV
Sbjct 195 GIAVDNARLFEESRTREAWIEATRDIGTQMLAGADPAMVFRLIAEEALTLMAGAATLVAV 254
Query 257 PVDEDMPAADVGELLVIETVGSAVASIVGRTIPVAGAVLREVFVNGIPRRVDRVDLEGLD 316
P+D++ PA +V +L+++E G ++ T+ V+G + VF + PRR DR+DL +D
Sbjct 255 PLDDEAPACEVDDLVIVEVAGEISPAVKQMTVAVSGTSIGGVFHDRTPRRFDRLDL-AVD 313
Query 317 ELADAGPALLLPLRARGTVAGVVVVLSQGGPGAFTDEQLEMMAAFADQAALAWQLATSQR 376
+ GPAL+LPLRA TVAGV+V L F+D+QL+MMAAFADQAALAW+LAT+QR
Sbjct 314 GPVEPGPALVLPLRAADTVAGVLVALRSADEQPFSDKQLDMMAAFADQAALAWRLATAQR 373
Query 377 RMRELDVLTDRDRIARDLHDHVIQRLFAIGLALQGAVPHERNPEVQQRLSDVVDDLQDVI 436
+MRE+++LTDRDRIARDLHDHVIQRLFA+GL LQGA P R P V++ + +DDLQ++I
Sbjct 374 QMREVEILTDRDRIARDLHDHVIQRLFAVGLTLQGAAPRARVPAVRESIYSSIDDLQEII 433
Query 437 QEIRTTIYDLHGASQGITRLRQRIDAAVAQFADSGLRTSVQFVGPLSVVDSALADQAEAV 496
QEIR+ I+DLH T LR R+D + Q A L T+VQ+ GPLSVVD+ LA+ AEAV
Sbjct 434 QEIRSAIFDLHAGPSRATGLRHRLDKVIDQLAIPALHTTVQYTGPLSVVDTVLANHAEAV 493
Query 497 VREAVSNAVRHAKASTLTVRVKVDDDLCIEVTDNGRGLPDEFTGSGLTNLRQRAEQAGGE 556
+REAVSNAVRHA A++L + V V+DD+ +EV D+G G+ + T SGL NLRQRA+ AGGE
Sbjct 494 LREAVSNAVRHANATSLAINVSVEDDVRVEVVDDGVGISGDITESGLRNLRQRADDAGGE 553
Query 557 FTLASVPGASGTVLRWSAPL 576
FT+ ++P GT+LRWSAPL
Sbjct 554 FTVENMP-TGGTLLRWSAPL 572
>gi|167970443|ref|ZP_02552720.1| hypothetical histidine kinase response regulator [Mycobacterium
tuberculosis H37Ra]
gi|254551052|ref|ZP_05141499.1| histidine kinase response regulator [Mycobacterium tuberculosis
'98-R604 INH-RIF-EM']
gi|297634604|ref|ZP_06952384.1| histidine kinase response regulator [Mycobacterium tuberculosis
KZN 4207]
gi|297731592|ref|ZP_06960710.1| histidine kinase response regulator [Mycobacterium tuberculosis
KZN R506]
gi|313658925|ref|ZP_07815805.1| histidine kinase response regulator [Mycobacterium tuberculosis
KZN V2475]
Length=558
Score = 622 bits (1605), Expect = 4e-176, Method: Compositional matrix adjust.
Identities = 348/559 (63%), Positives = 441/559 (79%), Gaps = 2/559 (0%)
Query 18 LRHTLSQLRLHELLVEVQDRVEQIVEGRDRLDGLVEAMLVVTAGLDLEATLRAIVHSATS 77
+R TLSQLRL ELL+EVQDR+EQIVEGRDRLDGL++A+L +T+GL L+ATLRAIVH+A
Sbjct 1 MRETLSQLRLRELLLEVQDRIEQIVEGRDRLDGLIDAILAITSGLKLDATLRAIVHTAAE 60
Query 78 LVDARYGAMEVHDRQHRVLHFVYEGIDEETVRRIGHLPKGLGVIGLLIEDPKPLRLDDVS 137
LVDARYGA+ V HR++ FVYEGIDEET IG LP+G GV+G LIE+PKP+RLDD+S
Sbjct 61 LVDARYGALGVRGYDHRLVEFVYEGIDEETRHLIGSLPEGRGVLGALIEEPKPIRLDDIS 120
Query 138 AHPASIGFPPYHPPMRTFLGVPVRVRDESFGTLYLTDKTNGQPFSDDDEVLVQALAAAAG 197
HPAS+GFP +HPPMRTFLGVPVR+RDE FG LYLT+K +GQPFSDDDEVLVQALAAAAG
Sbjct 121 RHPASVGFPLHHPPMRTFLGVPVRIRDEVFGNLYLTEKADGQPFSDDDEVLVQALAAAAG 180
Query 198 IAVANARLYQQAKARQSWIEATRDIATELLSGTEPATVFRLVAAEALKLTAADAALVAVP 257
IAV NARL+++++ R++WIEATRDI T++L+G +PA VFRL+A EAL L A A LVAVP
Sbjct 181 IAVDNARLFEESRTREAWIEATRDIGTQMLAGADPAMVFRLIAEEALTLMAGAATLVAVP 240
Query 258 VDEDMPAADVGELLVIETVGSAVASIVGRTIPVAGAVLREVFVNGIPRRVDRVDLEGLDE 317
+D++ PA +V +L+++E G ++ T+ V+G + VF + PRR DR+DL +D
Sbjct 241 LDDEAPACEVDDLVIVEVAGEISPAVKQMTVAVSGTSIGGVFHDRTPRRFDRLDL-AVDG 299
Query 318 LADAGPALLLPLRARGTVAGVVVVLSQGGPGAFTDEQLEMMAAFADQAALAWQLATSQRR 377
+ GPAL+LPLRA TVAGV+V L F+D+QL+MMAAFADQAALAW+LAT+QR+
Sbjct 300 PVEPGPALVLPLRAADTVAGVLVALRSADEQPFSDKQLDMMAAFADQAALAWRLATAQRQ 359
Query 378 MRELDVLTDRDRIARDLHDHVIQRLFAIGLALQGAVPHERNPEVQQRLSDVVDDLQDVIQ 437
MRE+++LTDRDRIARDLHDHVIQRLFA+GL LQGA P R P V++ + +DDLQ++IQ
Sbjct 360 MREVEILTDRDRIARDLHDHVIQRLFAVGLTLQGAAPRARVPAVRESIYSSIDDLQEIIQ 419
Query 438 EIRTTIYDLHGASQGITRLRQRIDAAVAQFADSGLRTSVQFVGPLSVVDSALADQAEAVV 497
EIR+ I+DLH T LR R+D + Q A L T+VQ+ GPLSVVD+ LA+ AEAV+
Sbjct 420 EIRSAIFDLHAGPSRATGLRHRLDKVIDQLAIPALHTTVQYTGPLSVVDTVLANHAEAVL 479
Query 498 REAVSNAVRHAKASTLTVRVKVDDDLCIEVTDNGRGLPDEFTGSGLTNLRQRAEQAGGEF 557
REAVSNAVRHA A++L + V V+DD+ +EV D+G G+ + T SGL NLRQRA+ AGGEF
Sbjct 480 REAVSNAVRHANATSLAINVSVEDDVRVEVVDDGVGISGDITESGLRNLRQRADDAGGEF 539
Query 558 TLASVPGASGTVLRWSAPL 576
T+ ++P GT+LRWSAPL
Sbjct 540 TVENMP-TGGTLLRWSAPL 557
>gi|340627038|ref|YP_004745490.1| putative histidine kinase response regulator [Mycobacterium canettii
CIPT 140010059]
gi|340005228|emb|CCC44382.1| putative histidine kinase response regulator [Mycobacterium canettii
CIPT 140010059]
Length=573
Score = 613 bits (1580), Expect = 4e-173, Method: Compositional matrix adjust.
Identities = 350/560 (63%), Positives = 444/560 (80%), Gaps = 2/560 (0%)
Query 17 PLRHTLSQLRLHELLVEVQDRVEQIVEGRDRLDGLVEAMLVVTAGLDLEATLRAIVHSAT 76
PLR TLSQLRL ELL+EVQDR+EQIVEGRDRLDGL++A+L +T+GL L+ATLRAIVH+A
Sbjct 15 PLRETLSQLRLRELLLEVQDRIEQIVEGRDRLDGLIDAILAITSGLKLDATLRAIVHTAA 74
Query 77 SLVDARYGAMEVHDRQHRVLHFVYEGIDEETVRRIGHLPKGLGVIGLLIEDPKPLRLDDV 136
LVDARYGA+ V HR++ FVYEGIDEET IG LP+G GV+G LIE+PKP+RLDD+
Sbjct 75 ELVDARYGALGVRGYDHRLVEFVYEGIDEETRHLIGSLPEGRGVLGALIEEPKPIRLDDI 134
Query 137 SAHPASIGFPPYHPPMRTFLGVPVRVRDESFGTLYLTDKTNGQPFSDDDEVLVQALAAAA 196
+ HPAS+GFP +HPPMRTFLGVPVR+RDE FG LYLT+K +GQPFSDDDEVLVQALAAAA
Sbjct 135 ARHPASVGFPLHHPPMRTFLGVPVRIRDEVFGNLYLTEKADGQPFSDDDEVLVQALAAAA 194
Query 197 GIAVANARLYQQAKARQSWIEATRDIATELLSGTEPATVFRLVAAEALKLTAADAALVAV 256
GIAV NARL+++++ R++WIEATRDI T++L+G +PA VFRL+A EAL L AA A LVAV
Sbjct 195 GIAVDNARLFEESRTREAWIEATRDIGTQMLAGADPAMVFRLIAEEALTLMAAAATLVAV 254
Query 257 PVDEDMPAADVGELLVIETVGSAVASIVGRTIPVAGAVLREVFVNGIPRRVDRVDLEGLD 316
P+D++ PA +V +L+++E G ++ T+ V+G + VF + PRR DR+DL +D
Sbjct 255 PLDDEAPACEVDDLVIVEVAGEISPAVKQMTVAVSGTSIGGVFHDRTPRRFDRLDLT-VD 313
Query 317 ELADAGPALLLPLRARGTVAGVVVVLSQGGPGAFTDEQLEMMAAFADQAALAWQLATSQR 376
+ GPAL+LPLRA TVAGV+V L + F+D+QL+MMAAFADQAALAW+LAT+QR
Sbjct 314 GPVEPGPALVLPLRAADTVAGVLVALRRADEQPFSDKQLDMMAAFADQAALAWRLATAQR 373
Query 377 RMRELDVLTDRDRIARDLHDHVIQRLFAIGLALQGAVPHERNPEVQQRLSDVVDDLQDVI 436
+MRE+++LTDRDRIARDLHDHVIQRLFA+GL LQGA P R P V++ + +DDLQ++I
Sbjct 374 QMREVEILTDRDRIARDLHDHVIQRLFAVGLTLQGAAPRARVPAVRESIYSSIDDLQEII 433
Query 437 QEIRTTIYDLHGASQGITRLRQRIDAAVAQFADSGLRTSVQFVGPLSVVDSALADQAEAV 496
QEIR+ I+DLH T LR R+D + Q A L T+VQ+ GPLSVVD+ LA+ AEAV
Sbjct 434 QEIRSAIFDLHAGPSRATGLRHRLDKVIDQLAIPALHTTVQYTGPLSVVDTVLANHAEAV 493
Query 497 VREAVSNAVRHAKASTLTVRVKVDDDLCIEVTDNGRGLPDEFTGSGLTNLRQRAEQAGGE 556
+REAVSNAVRHA A++L + V V+DD+ +EV D+G G+ + T SGL NLRQRA+ AGGE
Sbjct 494 LREAVSNAVRHANATSLAINVSVEDDVRVEVVDDGVGISGDITESGLRNLRQRADDAGGE 553
Query 557 FTLASVPGASGTVLRWSAPL 576
FT+ ++P GT+LRWSAPL
Sbjct 554 FTVENMP-TGGTLLRWSAPL 572
>gi|333919784|ref|YP_004493365.1| GAF sensor signal transduction histidine kinase [Amycolicicoccus
subflavus DQS3-9A1]
gi|333482005|gb|AEF40565.1| GAF sensor signal transduction histidine kinase [Amycolicicoccus
subflavus DQS3-9A1]
Length=574
Score = 604 bits (1557), Expect = 1e-170, Method: Compositional matrix adjust.
Identities = 317/571 (56%), Positives = 417/571 (74%), Gaps = 6/571 (1%)
Query 9 ENDGAAMRPLRHTLSQLRLHELLVEVQDRVEQIVEGRDRLDGLVEAMLVVTAGLDLEATL 68
E G +R TLSQLRL ELL E Q R+E++++ +DR DGL+EAMLVVT+GLD++ TL
Sbjct 6 ETHGEQPGQVRGTLSQLRLRELLRETQQRIEEMIDSKDRTDGLIEAMLVVTSGLDIDVTL 65
Query 69 RAIVHSATSLVDARYGAMEVHDRQHRVLHFVYEGIDEETVRRIGHLPKGLGVIGLLIEDP 128
R IVH A LVDARYGA+ V H ++ F+YEGIDE T IG LP+G GV+GLLI+ P
Sbjct 66 RTIVHKAIELVDARYGALGVRGHDHSLVQFIYEGIDEHTRELIGPLPEGRGVLGLLIDQP 125
Query 129 KPLRLDDVSAHPASIGFPPYHPPMRTFLGVPVRVRDESFGTLYLTDKTNGQPFSDDDEVL 188
KP+R+DD+S HP+S+GFP +HPPM+TFLGVPVR+ +E FG LYLT+K +GQPF+ DDEVL
Sbjct 126 KPIRMDDLSRHPSSVGFPTHHPPMKTFLGVPVRIGEEVFGNLYLTEKNDGQPFTADDEVL 185
Query 189 VQALAAAAGIAVANARLYQQAKARQSWIEATRDIATELLSGTEPATVFRLVAAEALKLTA 248
V+ALA+AAGIA+AN+RLY+Q + RQ+WIEATRD++TELL+G +P VFR V +A +L
Sbjct 186 VEALASAAGIAIANSRLYEQGQTRQAWIEATRDVSTELLAGHDPDVVFRSVVTKANQLGD 245
Query 249 ADAALVAVPVDEDMPAADVGELLVIETVGSAVASIVGRTIPVAGAVLREVFVNGIPRRVD 308
+ + +A+P D ++P +V EL+++ET + R IP+ F+ P+R +
Sbjct 246 GEISFLALPEDPELPFNEVHELVIVETSEKGSGLLRNR-IPLGRTSFGAAFIEQNPQRCE 304
Query 309 RVDLEGLDELAD--AGPALLLPLRARGTVAGVVVVLSQGGPGAFTDEQLEMMAAFADQAA 366
R++L+ E++ +GPALLLPLRA + +GV+V+ FTDEQ+ MM FAD AA
Sbjct 305 RLELQ-FPEVSPQCSGPALLLPLRAEESNSGVLVIARSPNSPPFTDEQMGMMVGFADHAA 363
Query 367 LAWQLATSQRRMRELDVLTDRDRIARDLHDHVIQRLFAIGLALQGAVPHERNPEVQQRLS 426
LA +LA +Q R+RELD++ DRDRIARDLHDHVIQRLFAIGL+LQGA+P R PE++QR+S
Sbjct 364 LALRLADAQARVRELDIIADRDRIARDLHDHVIQRLFAIGLSLQGAIPRTRTPEIRQRIS 423
Query 427 DVVDDLQDVIQEIRTTIYDLHGASQGITRLRQRIDAAVAQFA-DSGLRTSVQFVGPLSVV 485
D DDLQ VIQEIRT I+DLHG + G LR+R+D A++Q DS LRTSV GPLSVV
Sbjct 424 DATDDLQTVIQEIRTAIFDLHGGTHGAVGLRKRLDEAISQLTRDSSLRTSVHIAGPLSVV 483
Query 486 DSALADQAEAVVREAVSNAVRHAKASTLTVRVKVDDDLCIEVTDNGRGLPDEFTGSGLTN 545
+ LAD AEAV+REAVSNAVRHA +LT+ + VD+DL IEV D+G G+P SGL N
Sbjct 484 EPELADHAEAVLREAVSNAVRHAHGKSLTINIGVDNDLKIEVIDDGVGVPAGTPQSGLKN 543
Query 546 LRQRAEQAGGEFTLASVPGASGTVLRWSAPL 576
++ RA+ G+F++ S G GT + WSAPL
Sbjct 544 MQSRADDLDGDFSVTSTAGG-GTRVVWSAPL 573
>gi|111017071|ref|YP_700043.1| sensor kinase, two-component system [Rhodococcus jostii RHA1]
gi|110816601|gb|ABG91885.1| sensor kinase, two-component system [Rhodococcus jostii RHA1]
Length=573
Score = 596 bits (1536), Expect = 5e-168, Method: Compositional matrix adjust.
Identities = 316/546 (58%), Positives = 407/546 (75%), Gaps = 3/546 (0%)
Query 33 EVQDRVEQIVEGRDRLDGLVEAMLVVTAGLDLEATLRAIVHSATSLVDARYGAMEVHDRQ 92
EVQ+R+EQIV+ RD +DGL+EAML VT+GLDL+ TL IVH+A +LVDARYGA+ V
Sbjct 28 EVQERIEQIVDARDHVDGLLEAMLAVTSGLDLDNTLHTIVHAAINLVDARYGALGVLGPG 87
Query 93 HRVLHFVYEGIDEETVRRIGHLPKGLGVIGLLIEDPKPLRLDDVSAHPASIGFPPYHPPM 152
+ FV+EGIDEET RIG LP+G GV+G LI +PKP+RLDD+S H AS+GFP HPPM
Sbjct 88 GGLSEFVFEGIDEETRERIGDLPRGRGVLGFLITNPKPVRLDDLSHHSASVGFPAEHPPM 147
Query 153 RTFLGVPVRVRDESFGTLYLTDKTNGQPFSDDDEVLVQALAAAAGIAVANARLYQQAKAR 212
+TFLGVP+++RDE FG LYLT+K NG F++DDEVL++ALAAAAGIA+ NARLY++++ R
Sbjct 148 KTFLGVPIQIRDEVFGNLYLTEKANGSQFTEDDEVLLRALAAAAGIAIENARLYEESRTR 207
Query 213 QSWIEATRDIATELLSGTEPATVFRLVAAEALKLTAADAALVAVPVDEDMPAADVGELLV 272
Q+W+EATR+IATELL+G+E A V +++A +AL LT AD+A +AVP D D+P+ +V EL+V
Sbjct 208 QAWLEATREIATELLAGSETAEVLQVIADDALALTGADSAFLAVPDDPDIPSDEVTELVV 267
Query 273 IETVGSAVASIVGRTIPVAGAVLREVFVNGIPRRVDRVDLE-GLDELADAGPALLLPLRA 331
+ G+ I+GRTIPV + E F P RV + + G + GPAL LPLRA
Sbjct 268 TASAGTVSDRIIGRTIPVDKSTSGEAFRERTPLRVTALAFDPGFETGTRFGPALALPLRA 327
Query 332 RGTVAGVVVVLSQGGPGAFTDEQLEMMAAFADQAALAWQLATSQRRMRELDVLTDRDRIA 391
+V GV+V L FTD+QL +M+ FADQAA+A QLA SQRRMRELDVL+DRDRIA
Sbjct 328 AQSVTGVLVTLRHVDALPFTDDQLALMSGFADQAAVALQLANSQRRMRELDVLSDRDRIA 387
Query 392 RDLHDHVIQRLFAIGLALQGAVPHERNPEVQQRLSDVVDDLQDVIQEIRTTIYDLHGASQ 451
RDLHDHVIQRLFA+GL+LQ + + P V+QRL +DDL D++++IRT I+DLHG S
Sbjct 388 RDLHDHVIQRLFAVGLSLQSTLQRAKAPIVKQRLEQSIDDLHDIVRDIRTAIFDLHGGSG 447
Query 452 GITRLRQRIDAAVAQ-FADSGLRTSVQFVGPLSVVDSALADQAEAVVREAVSNAVRHAKA 510
G+T+ R+R+ VA+ ADSGLRT+V GPLSV+D+ALAD AEAV+REA+SNAVRHA A
Sbjct 448 GMTQFRRRLHEIVAETTADSGLRTTVHMSGPLSVIDAALADHAEAVLREALSNAVRHAGA 507
Query 511 STLTVRVKVDDDLCIEVTDNGRGLPDEFTGSGLTNLRQRAEQAGGEFTLASVPGASGTVL 570
T+TV + V DDL IEV D+G+G + SGL NL RA + G F + + PG GT L
Sbjct 508 DTVTVSISVYDDLAIEVADDGKGFVENVVTSGLENLAARAREVNGHFAIDTTPGG-GTTL 566
Query 571 RWSAPL 576
RW+APL
Sbjct 567 RWTAPL 572
>gi|226359607|ref|YP_002777385.1| two-component histidine kinase DevS [Rhodococcus opacus B4]
gi|226238092|dbj|BAH48440.1| two-component histidine kinase DevS [Rhodococcus opacus B4]
Length=576
Score = 577 bits (1486), Expect = 3e-162, Method: Compositional matrix adjust.
Identities = 317/546 (59%), Positives = 402/546 (74%), Gaps = 3/546 (0%)
Query 33 EVQDRVEQIVEGRDRLDGLVEAMLVVTAGLDLEATLRAIVHSATSLVDARYGAMEVHDRQ 92
EVQDR+ QIV+ RD +DGL+EAML VT+GLDL+ TLR IVH+A LVDARYGA+ V
Sbjct 31 EVQDRIAQIVDVRDHVDGLLEAMLAVTSGLDLDNTLRTIVHAAIDLVDARYGALGVLAPT 90
Query 93 HRVLHFVYEGIDEETVRRIGHLPKGLGVIGLLIEDPKPLRLDDVSAHPASIGFPPYHPPM 152
+ FVYEGID+ET RIG LP+G GV+G LI DPKP+RL D+S HP S+GFPP HPPM
Sbjct 91 EGLSEFVYEGIDQETRERIGDLPRGRGVLGFLITDPKPVRLVDLSRHPVSVGFPPDHPPM 150
Query 153 RTFLGVPVRVRDESFGTLYLTDKTNGQPFSDDDEVLVQALAAAAGIAVANARLYQQAKAR 212
+TFLGVP++VRDE FG LYLT+K NG F++DDEVL++ALAAAAGIA+ NARLY++++ R
Sbjct 151 KTFLGVPIQVRDEVFGNLYLTEKANGAQFTEDDEVLLRALAAAAGIAIENARLYEESRTR 210
Query 213 QSWIEATRDIATELLSGTEPATVFRLVAAEALKLTAADAALVAVPVDEDMPAADVGELLV 272
Q+W+EATR+IATELL+G+E A V +++A +AL LTAAD+A +AVP D D+P+ +V EL+V
Sbjct 211 QAWLEATREIATELLAGSETADVLQVIADDALALTAADSAFLAVPDDPDIPSDEVTELVV 270
Query 273 IETVGSAVASIVGRTIPVAGAVLREVFVNGIPRRVDRVDLE-GLDELADAGPALLLPLRA 331
+ G+ I+GR IPV + E F P RV + + G + A GPAL LPLRA
Sbjct 271 TASAGTVSDRIIGRAIPVERSTSGEAFRERTPLRVSALAFDPGFETGARFGPALALPLRA 330
Query 332 RGTVAGVVVVLSQGGPGAFTDEQLEMMAAFADQAALAWQLATSQRRMRELDVLTDRDRIA 391
+V+GV+V L FTD+QL +M+ FADQAA+A QLA SQRRM ELDVL+DRDRIA
Sbjct 331 AQSVSGVLVTLRHVDASPFTDDQLALMSGFADQAAVALQLANSQRRMHELDVLSDRDRIA 390
Query 392 RDLHDHVIQRLFAIGLALQGAVPHERNPEVQQRLSDVVDDLQDVIQEIRTTIYDLHGASQ 451
RDLHDHVIQRLFA+GL+LQ + + P V+ RL +DDL D++++IRT I+DLHG S
Sbjct 391 RDLHDHVIQRLFAVGLSLQSTLQRAKAPVVKDRLEQSIDDLHDIVRDIRTAIFDLHGGSG 450
Query 452 GITRLRQRIDAAVAQ-FADSGLRTSVQFVGPLSVVDSALADQAEAVVREAVSNAVRHAKA 510
GIT+ R+R+ VA+ ADSGLRT+V GPLSV+D+ LA+ AEAV+REA+SNAVRHA A
Sbjct 451 GITQFRRRLHEIVAETTADSGLRTTVHMSGPLSVIDATLAEHAEAVLREALSNAVRHAGA 510
Query 511 STLTVRVKVDDDLCIEVTDNGRGLPDEFTGSGLTNLRQRAEQAGGEFTLASVPGASGTVL 570
T+TV + V DDL IEV D+G+G SGL NL RA + G + S G GT L
Sbjct 511 DTVTVSISVYDDLAIEVADDGKGFEGSVLTSGLDNLAARAREVNGHCAVDSTLGG-GTTL 569
Query 571 RWSAPL 576
RWSAPL
Sbjct 570 RWSAPL 575
>gi|302526810|ref|ZP_07279152.1| predicted protein [Streptomyces sp. AA4]
gi|302435705|gb|EFL07521.1| predicted protein [Streptomyces sp. AA4]
Length=570
Score = 533 bits (1373), Expect = 3e-149, Method: Compositional matrix adjust.
Identities = 305/571 (54%), Positives = 395/571 (70%), Gaps = 17/571 (2%)
Query 16 RPLRHTLSQLRLHELLVEVQDRVEQIVEGRDRLDGLVEAMLVVTAGLDLEATLRAIVHSA 75
R L TLSQLRL E L ++Q+R+E ++ RD++DGL+EA+L V +GL+L+ATLR IV +A
Sbjct 6 RKLSGTLSQLRLRETLRDLQERIELLIGTRDKMDGLLEAVLAVASGLELDATLRRIVQAA 65
Query 76 TSLVDARYGAMEVHDRQHRVLHFVYEGIDEETVRRIGHLPKGLGVIGLLIEDPKPLRLDD 135
L +A YGA+ V + FVY GID ET +RIGHLP+G G++GL+I+D KPLRL +
Sbjct 66 VELGEAHYGALGVLGDDGALAEFVYLGIDAETRKRIGHLPEGHGLLGLVIDDAKPLRLTE 125
Query 136 VSAHPASIGFPPYHPPMRTFLGVPVRVRDESFGTLYLTDKTNGQPFSDDDEVLVQALAAA 195
+SAHPAS+GFP HPPM +FLGVPVRVR+E FG LYLT+K +G F+DDDEV+VQALAAA
Sbjct 126 ISAHPASVGFPANHPPMHSFLGVPVRVREEVFGNLYLTEKKDGAEFTDDDEVIVQALAAA 185
Query 196 AGIAVANARLYQQAKARQSWIEATRDIATELLSGTEPATVFRLVAAEALKLTAADAALVA 255
AGIA+ NA LY+Q + RQ W+ AT ++ TELL GT+P L+A AL+LT +D L+A
Sbjct 186 AGIAIENAHLYEQTRLRQRWLGATSEVTTELLGGTDPVDALELIAGRALELTGSDVTLLA 245
Query 256 VP------VDEDMPAADVGELLVIETVGSAVASIVGRTIPVAGAVLREVFVNGIPRRVDR 309
+P VDED AD EL V G V + G +PV G+V V+ + PRR+
Sbjct 246 LPGTGRLDVDEDW-YADSAELTVTVCAGGDVRDLTGLRMPVDGSVPGAVYRDRTPRRMAE 304
Query 310 VDLEGLDELAD--AGPALLLPLRARGTVAGVVVVLSQGGPGAFTDEQLEMMAAFADQAAL 367
+ L L D GPAL++PLRA +GV++ L + G F QL ++A+FADQAAL
Sbjct 305 LAL-----LPDRGRGPALVVPLRAGDHTSGVLIALREPGSALFETAQLPVLASFADQAAL 359
Query 368 AWQLATSQRRMRELDVLTDRDRIARDLHDHVIQRLFAIGLALQGAVPHERNPEVQQRLSD 427
A QLA+ QR RE DVL+DRDRIARDLHDHVIQRLFA+GLA+Q + PE+Q+RL +
Sbjct 360 ALQLASQQRAARERDVLSDRDRIARDLHDHVIQRLFAVGLAMQSTQRRAKTPELQRRLQE 419
Query 428 VVDDLQDVIQEIRTTIYDLHGASQGITRLRQRIDAAVAQFADSG-LRTSVQFVGPLSVVD 486
+D + ++++EIRT I+DLHG + G RLR R+ A+A+ D L +V GPL V
Sbjct 420 SIDQMHEIVREIRTAIFDLHGGAAGEARLRNRLHDAIAELTDDAPLHPAVSMAGPLDAVP 479
Query 487 SALADQAEAVVREAVSNAVRHAKASTLTVRVKVDDDLC-IEVTDNGRGLPDEFTGSGLTN 545
+ LA+ EAVVREAVSNAVRHA AS L+V V V D++ I VTD+G GLP+E + SGL N
Sbjct 480 AQLAEHVEAVVREAVSNAVRHAGASALSVSVAVRDEVVRISVTDDGTGLPEEVSPSGLGN 539
Query 546 LRQRAEQAGGEFTLASVPGASGTVLRWSAPL 576
LR+RAE AGGEF L S PG G + WSAPL
Sbjct 540 LRERAESAGGEFVLGSGPGG-GVRVEWSAPL 569
>gi|343925109|ref|ZP_08764641.1| two-component histidine kinase DevS [Gordonia alkanivorans NBRC
16433]
gi|343765040|dbj|GAA11567.1| two-component histidine kinase DevS [Gordonia alkanivorans NBRC
16433]
Length=575
Score = 526 bits (1355), Expect = 4e-147, Method: Compositional matrix adjust.
Identities = 278/568 (49%), Positives = 379/568 (67%), Gaps = 4/568 (0%)
Query 12 GAAMRPLRHTLSQLRLHELLVEVQDRVEQIVEGRDRLDGLVEAMLVVTAGLDLEATLRAI 71
G +++ LSQ+RL ELL EV+DR+ QI + RDR+DGL+EAML+V++ LDLE TL AI
Sbjct 9 GVGSFEVQNELSQMRLRELLDEVRDRITQIADVRDRIDGLLEAMLMVSSDLDLETTLEAI 68
Query 72 VHSATSLVDARYGAMEVHDRQHRVLHFVYEGIDEETVRRIGHLPKGLGVIGLLIEDPKPL 131
V + T LVDA YGA+ V H + F+ +GI E+ IGHLP G GV+G LI+DP+ L
Sbjct 69 VSAGTRLVDAEYGAVGVLGSGHDLSAFLAQGIGEDVRAEIGHLPTGRGVLGQLIDDPRVL 128
Query 132 RLDDVSAHPASIGFPPYHPPMRTFLGVPVRVRDESFGTLYLTDKTNGQPFSDDDEVLVQA 191
RL D+S HPAS+GFPP HPPM +FLG P+RVRDE FG LYLT+K NG F++DDE+++QA
Sbjct 129 RLTDLSEHPASVGFPPNHPPMTSFLGAPIRVRDEIFGNLYLTEKKNGALFTEDDELVIQA 188
Query 192 LAAAAGIAVANARLYQQAKARQSWIEATRDIATELLSGTEPATVFRLVAAEALKLTAADA 251
LA+AAGIA+ NARLY+QA+ + +WIEA RD+ ELL+G + V +A + L L AD
Sbjct 189 LASAAGIAIENARLYEQAQTQLAWIEANRDVIAELLTGADQQDVLESIARKVLTLADADL 248
Query 252 ALVAVPVDEDMPAADVGELLVIETVGSAVASIVGRTIPVAGAVLREVFVNGIP--RRVDR 309
+A P D +MPA V EL+V G GRT+P+ G+ + FV P R
Sbjct 249 VCIAEPHDHEMPAESVEELVVTVAEGVDAEVFRGRTVPIKGSTSGDAFVRRRPVLREELE 308
Query 310 VDLEGLDELADAGPALLLPLRARGTVAGVVVVLSQGGPGAFTDEQLEMMAAFADQAALAW 369
D+ G D GP ++ PLR + GV++ + G F ++ L + A FADQ ALA
Sbjct 309 YDISG-DSSTQHGPVMVAPLRTAESTRGVLIAVRSKGRDGFAEDLLSLSANFADQGALAL 367
Query 370 QLATSQRRMRELDVLTDRDRIARDLHDHVIQRLFAIGLALQGAVPHERNPEVQQRLSDVV 429
QLA++ + E+ VL DR+RIARDLHDHVIQR+FA GL LQ + ++ E++ RL+ +
Sbjct 368 QLASATNQAHEMRVLEDRERIARDLHDHVIQRIFAEGLTLQATLQRTQSSEIRARLTRSI 427
Query 430 DDLQDVIQEIRTTIYDLHGASQGITRLRQRIDAAV-AQFADSGLRTSVQFVGPLSVVDSA 488
++LQD++Q++R+TI+DL TRLRQR+ + Q D ++T V+ GPLS+V+
Sbjct 428 NNLQDIVQDVRSTIFDLQAEETETTRLRQRVQETIDQQIDDLPIQTHVRMAGPLSIVEPR 487
Query 489 LADQAEAVVREAVSNAVRHAKASTLTVRVKVDDDLCIEVTDNGRGLPDEFTGSGLTNLRQ 548
LADQ AVVREA+SNAVR+A A+T+TV + V D+L +EVTD+G GLP++ T SGL NLR
Sbjct 488 LADQVVAVVREALSNAVRYAHATTVTVAISVGDELAVEVTDDGVGLPEDVTPSGLKNLRH 547
Query 549 RAEQAGGEFTLASVPGASGTVLRWSAPL 576
RA+Q GG F L + G +RW+ PL
Sbjct 548 RAKQLGGAFALNTPDSGRGLSVRWAVPL 575
>gi|326385155|ref|ZP_08206823.1| sensor kinase, two-component system [Gordonia neofelifaecis NRRL
B-59395]
gi|326196120|gb|EGD53326.1| sensor kinase, two-component system [Gordonia neofelifaecis NRRL
B-59395]
Length=576
Score = 525 bits (1351), Expect = 1e-146, Method: Compositional matrix adjust.
Identities = 294/571 (52%), Positives = 384/571 (68%), Gaps = 2/571 (0%)
Query 8 DENDGAAMRPLRHTLSQLRLHELLVEVQDRVEQIVEGRDRLDGLVEAMLVVTAGLDLEAT 67
+EN R R LSQ+RL EL+ E+Q+R+ QI + R+ L+EAML VT GL LE T
Sbjct 5 EENARERSREFRSALSQMRLSELVDELQERLTQITDFPRRMAALMEAMLAVTTGLRLEDT 64
Query 68 LRAIVHSATSLVDARYGAMEVHDRQHRVLHFVYEGIDEETVRRIGHLPKGLGVIGLLIED 127
L+++V +A LVDA YGA+ V H + FV +GIDE+TV +G P G GV+G+LI++
Sbjct 65 LQSVVGAAARLVDAEYGALGVRGEDHHLSAFVNQGIDEDTVALLGPPPTGRGVLGVLIDE 124
Query 128 PKPLRLDDVSAHPASIGFPPYHPPMRTFLGVPVRVRDESFGTLYLTDKTNGQPFSDDDEV 187
PK LRLDD+S HP S+GFPP+HPPM TFLG P+RVRD+ FG LYLT+K G PF+DDDEV
Sbjct 125 PKVLRLDDLSRHPDSVGFPPHHPPMTTFLGAPIRVRDKVFGNLYLTEKRGGGPFTDDDEV 184
Query 188 LVQALAAAAGIAVANARLYQQAKARQSWIEATRDIATELLSGTEPATVFRLVAAEALKLT 247
++ ALA+ AGIA+ NARLY+Q++ + WIEATRD+ TELLSG E V R++A +AL LT
Sbjct 185 IIVALASIAGIAIDNARLYEQSQLQLGWIEATRDVRTELLSGAENRDVLRMLARKALTLT 244
Query 248 AADAALVAVPVDEDMPAADVGELLVIETVGSAVASIVGRTIPVAGAVLREVFVNGIPRRV 307
AD VA P D + PA V EL+V G + G TIPVAG+ F P R
Sbjct 245 DADLVFVAQPDDPEHPADMVRELIVTVAEGRSSGDEEGATIPVAGSTSGAAFTRREPIRR 304
Query 308 DRVDLEGLDELAD-AGPALLLPLRARGTVAGVVVVLSQGGPGAFTDEQLEMMAAFADQAA 366
DR++ +D++ GP L PLRA T +GV+V+L G F+D LE+ A FADQAA
Sbjct 305 DRLEYTRIDDIGTRYGPVLAAPLRAADTTSGVLVILRNVGRPQFSDHLLELCAGFADQAA 364
Query 367 LAWQLATSQRRMRELDVLTDRDRIARDLHDHVIQRLFAIGLALQGAVPHERNPEVQQRLS 426
LA +LA + R++++L DR+RIA DLHDHVIQR+FA G+ALQ + + +V+ RL+
Sbjct 365 LALELAARTTQARQVEMLADRERIANDLHDHVIQRIFAEGMALQATLQRTASADVRARLT 424
Query 427 DVVDDLQDVIQEIRTTIYDLHGASQGITRLRQRI-DAAVAQFADSGLRTSVQFVGPLSVV 485
VD+LQDV+QEIR+TI+DLH TRLRQRI D Q D+ L T ++ GPLSVV
Sbjct 425 RSVDNLQDVVQEIRSTIFDLHSDDTATTRLRQRIHDVVDEQVGDAPLETHIRLSGPLSVV 484
Query 486 DSALADQAEAVVREAVSNAVRHAKASTLTVRVKVDDDLCIEVTDNGRGLPDEFTGSGLTN 545
+A+Q AV+REAVSN VRHA A T+TV V V D++ +EV D+G GLPD+ T SGL +
Sbjct 485 APDVAEQLVAVLREAVSNVVRHAHACTMTVAVSVGDEITLEVVDDGVGLPDDITPSGLAS 544
Query 546 LRQRAEQAGGEFTLASVPGASGTVLRWSAPL 576
+R+RAE GE +L A G V+RWS PL
Sbjct 545 MRRRAESLSGELSLTPADDARGLVVRWSVPL 575
>gi|317507620|ref|ZP_07965333.1| GAF domain-containing protein [Segniliparus rugosus ATCC BAA-974]
gi|316254097|gb|EFV13454.1| GAF domain-containing protein [Segniliparus rugosus ATCC BAA-974]
Length=569
Score = 512 bits (1319), Expect = 7e-143, Method: Compositional matrix adjust.
Identities = 286/561 (51%), Positives = 379/561 (68%), Gaps = 5/561 (0%)
Query 22 LSQLRLHELLVEVQDRVEQIV-EGRDRLDGLVEAMLVVTAGLDLEATLRAIVHSATSLVD 80
L+Q +L ELLVE+Q+R+E+IV + + R+ GL++A++ V++GL+L+ TL IV +A LV+
Sbjct 10 LAQTQLRELLVEIQERIEEIVADSQTRMAGLLDAVVAVSSGLELDVTLHKIVRAAIDLVN 69
Query 81 ARYGAMEVHDRQHRVLHFVYEGIDEETVRRIGHLPKGLGVIGLLIEDPKPLRLDDVSAHP 140
ARYGA+ V R + FV+ GIDE T IG LP G GV+G++I++ KPLRL D+S HP
Sbjct 70 ARYGALGVLGRDGTLSQFVHVGIDEATRELIGPLPTGRGVLGVVIDEAKPLRLADISEHP 129
Query 141 ASIGFPPYHPPMRTFLGVPVRVRDESFGTLYLTDKTNGQPFSDDDEVLVQALAAAAGIAV 200
ASIGFPP HPPMRTFLGVPV VR + FG LYL +K G F++DDEV+V+ LA+AAGIA+
Sbjct 130 ASIGFPPNHPPMRTFLGVPVEVRGQVFGRLYLAEKHGGHQFTEDDEVVVRTLASAAGIAI 189
Query 201 ANARLYQQAKARQSWIEATRDIATELLSGTEPATVFRLVAAEALKLTAADAALVAVPVDE 260
NARLY QA+ RQ W++AT +I ELL GT+ RL+A + L AD AL+A+P D
Sbjct 190 ENARLYAQARKRQQWLQATAEITAELLRGTDLPQALRLIAVRSASLVGADYALIALPDDL 249
Query 261 DMPAADVGELLVIETVGSAVASIVGRTIPVAGAVLREVFVNGIPRRVDRVDLEGLDELAD 320
+V EL + G +++G T+PV G+ VF N PR V + L+ ++
Sbjct 250 LAGPEEVQELRFVACSGLDERTMIGMTVPVEGSTSGTVFQNRAPRSVSALALDLSEQTGI 309
Query 321 A-GPALLLPLRARGTVAGVVVVLSQGGPGAFTDEQLEMMAAFADQAALAWQLATSQRRMR 379
A GPAL+LPLR+ +V GV++++ G F ++QL+ +A+FADQAALA + A +
Sbjct 310 AFGPALVLPLRSAESVTGVLLLIRSAGAAPFGEDQLDAVASFADQAALALEQAEIRSAKH 369
Query 380 ELDVLTDRDRIARDLHDHVIQRLFAIGLALQGAVPH-ERNPEVQQRLSDVVDDLQDVIQE 438
ELDVL +RDRIARDLHDHVIQ+LFAIGL++Q +R PEV RL++ VD L D+IQ+
Sbjct 370 ELDVLAERDRIARDLHDHVIQQLFAIGLSMQSTQRRSQRIPEVAGRLTEHVDQLHDIIQD 429
Query 439 IRTTIYDLHGASQGITRLRQRIDAAVAQFA-DSGLRTSVQFVGPLSVVDSALADQAEAVV 497
IRT I+DLH A++G T LR + A VA+ DSGLR +V GPL VV ++A EAV+
Sbjct 430 IRTAIFDLHAANRGETSLRSSVRAVVAKLTDDSGLRVTVHMTGPLDVVPESIARDGEAVL 489
Query 498 REAVSNAVRHAKASTLTVRVKVDDDLCIEVTDNGRGLPDEFTGSGLTNLRQRAEQAGGEF 557
REAVSNAVRHA AS L+V V VDD IEV DNG G+P+ SGL NL +RA GG+F
Sbjct 490 REAVSNAVRHASASELSVAVSVDDHFVIEVVDNGVGIPEAVAHSGLRNLAERALAHGGQF 549
Query 558 TLASVPGASGTVLRWSAPLSQ 578
ASV GT L W L Q
Sbjct 550 EAASV-ATGGTRLFWRVRLPQ 569
>gi|54024863|ref|YP_119105.1| putative two-component system sensor kinase [Nocardia farcinica
IFM 10152]
gi|54016371|dbj|BAD57741.1| putative two-component system sensor kinase [Nocardia farcinica
IFM 10152]
Length=583
Score = 504 bits (1299), Expect = 1e-140, Method: Compositional matrix adjust.
Identities = 300/566 (54%), Positives = 397/566 (71%), Gaps = 7/566 (1%)
Query 17 PLRHTLSQLRLHELLVEVQDRVEQIVEGRDRLDGLVEAMLVVTAGLDLEATLRAIVHSAT 76
P+ TL+Q RL ELL EVQDR+ +IV RD++D L+EAMLVVTAGLDL+ TLR+IVH+A
Sbjct 18 PVIETLAQSRLRELLAEVQDRIAEIVNVRDQMDRLIEAMLVVTAGLDLDNTLRSIVHTAI 77
Query 77 SLVDARYGAMEVH--DRQHRVL-HFVYEGIDEETVRRIGHLPKGLGVIGLLIEDPKPLRL 133
LVDA+YGA+ V DR + L FVYEGID+ T IG LP+G GV+GLLI+DP+P+RL
Sbjct 78 ELVDAKYGALGVRESDRDSKELAEFVYEGIDDRTRVLIGDLPRGHGVLGLLIDDPRPIRL 137
Query 134 DDVSAHPASIGFPPYHPPMRTFLGVPVRVRDESFGTLYLTDKTNGQPFSDDDEVLVQALA 193
D+SAHPAS+GFP +HPPMRTFLGVPV+V E FG LYLT+K G F++DDEV+VQALA
Sbjct 138 ADMSAHPASVGFPDHHPPMRTFLGVPVQVGGEVFGNLYLTEKAGGHEFTEDDEVVVQALA 197
Query 194 AAAGIAVANARLYQQAKARQSWIEATRDIATELLSGTEPATVFRLVAAEALKLTAADAAL 253
AAAGIA+ANARLY++++ RQ W+EAT+ +AT LL+G E + VF ++ AL LT + A
Sbjct 198 AAAGIAIANARLYEESRIRQQWLEATQQVATRLLAGGETSEVFTVITERALALTGSACAF 257
Query 254 VAVPVDEDMPAADVGELLVIETVGSAVASIVGRTIPVAGAVLREVFVNGIPRRVDRVDLE 313
+A+P D D+P D+ EL+V+ G+ ++ G +P+ F +G P VD D
Sbjct 258 LALPEDPDVPPEDLTELVVVAAAGADADTLTGTRLPMDETHTGVAFRDGRPLAVDTADAP 317
Query 314 GLDELADAGPALLLPLRARGTVAGVVVVLSQGGPGAFTDEQLEMMAAFADQAALAWQLAT 373
+ GP L LPLRA V G++ + G MM+AFADQAALA Q+A
Sbjct 318 SFATSLEYGPVLTLPLRAGNAVVGLLTTMRALGMPPVDAAGQAMMSAFADQAALALQMAA 377
Query 374 SQRRMRELDVLTDRDRIARDLHDHVIQRLFAIGLALQGAVPHERNPEVQQRLSDVVDDLQ 433
+QRRMRELDV+++RDRIARDLHDHVIQRLFA+GL+LQ V R PE++ RL D V+D+Q
Sbjct 378 TQRRMRELDVVSERDRIARDLHDHVIQRLFAVGLSLQSTVSRARAPEIKTRLMDTVNDVQ 437
Query 434 DVIQEIRTTIYDLHGASQG-ITRLRQRIDAAVAQFA-DSGLRTSVQFVGPLSVVDSALAD 491
++QEIR +I+DLH +S LR+R+ A +A+ ++ LRTS++ GP+SV+ A+ D
Sbjct 438 SIVQEIRHSIFDLHSSSAAEAPALRKRLHAVLAEMTEETDLRTSIRLSGPVSVLAPAMFD 497
Query 492 QAEAVVREAVSNAVRHAKASTLTVRVKVDDDLCIEVTDNGRGLPDEFT-GSGLTNLRQRA 550
EAV+REAVSN VRHAKAS+L+VR+ + DD+ +E+ DNG GLP++ SGL N+ R
Sbjct 498 DVEAVLREAVSNVVRHAKASSLSVRLTIRDDVELEIVDNGIGLPEDLPRRSGLANMAART 557
Query 551 EQAGGEFTLASVPGASGTVLRWSAPL 576
E+AGG F A GTV+ WS PL
Sbjct 558 EKAGGTFR-AERGRDGGTVIHWSVPL 582
>gi|169630969|ref|YP_001704618.1| histidine kinase response regulator [Mycobacterium abscessus
ATCC 19977]
gi|169242936|emb|CAM63964.1| Probable histidine kinase response regulator [Mycobacterium abscessus]
Length=567
Score = 488 bits (1256), Expect = 1e-135, Method: Compositional matrix adjust.
Identities = 293/572 (52%), Positives = 384/572 (68%), Gaps = 12/572 (2%)
Query 9 ENDGAAMRPLRHTLSQLRLHELLVEVQDRVEQIVEG-RDRLDGLVEAMLVVTAGLDLEAT 67
E+ GA + L+ L+L ELL EVQ R+EQIV+G R R+D L++A++ V++GL+L+AT
Sbjct 3 EDVGAQPNRVTAELAHLQLRELLAEVQGRIEQIVDGTRGRMDALLDAVMAVSSGLELDAT 62
Query 68 LRAIVHSATSLVDARYGAMEVHDRQHRVLHFVYEGIDEETVRRIGHLPKGLGVIGLLIED 127
LR IV +A+ LV ARYGA+ V ++ FVYEGIDE T IG LP G GV+G++I++
Sbjct 63 LREIVCAASELVSARYGALGVVGSDEKLAEFVYEGIDEATRDLIGPLPTGHGVLGVVIDE 122
Query 128 PKPLRLDDVSAHPASIGFPPYHPPMRTFLGVPVRVRDESFGTLYLTDKTNGQPFSDDDEV 187
KPLRL D++AHPAS+GFP HPPMRTFLGVPV+VR E FG LYLT+K +GQ F++DDEV
Sbjct 123 AKPLRLRDIAAHPASVGFPANHPPMRTFLGVPVQVRGEVFGRLYLTEKLDGQEFTEDDEV 182
Query 188 LVQALAAAAGIAVANARLYQQAKARQSWIEATRDIATELLSGTEPATVFRLVAAEALKLT 247
+V+ALA AAGIA+ NARLYQ A+ R+ W AT DI ELL G +P LVA+ A L
Sbjct 183 VVRALAGAAGIAIENARLYQHARRREQWQRATADITAELLGGVDPGKALHLVASSAALLA 242
Query 248 AADAALVAVPVDEDMPAADVGELLVIETVGSAVASIVGRTIPVAGAVLREVFVNGIPRRV 307
AD A +A+P ++ D EL+V G + + IP+ G+ F++ PR V
Sbjct 243 EADFAFIALPAGDE---EDTAELVVAVCEGKGAEVLNDKLIPIDGSTSGSTFIDHEPRNV 299
Query 308 DR--VDLEGLDELADAGPALLLPLRARGTVAGVVVVLSQGGPGAFTDEQLEMMAAFADQA 365
R V+L +LA GPAL+LPL + AGV+++L G AF +EQL+M A+FA QA
Sbjct 300 GRLAVNLAEGTDLA-FGPALVLPLGGGESTAGVLILLRTVGAIAFDEEQLDMAASFAGQA 358
Query 366 ALAWQLATSQRRMRELDVLTDRDRIARDLHDHVIQRLFAIGLALQGAVPHERNPEVQQRL 425
ALA + A + ELDVL DRDRIARDLHDHVIQRLFA+GLA+Q +P V RL
Sbjct 359 ALALEQAEVRLAKHELDVLADRDRIARDLHDHVIQRLFAVGLAMQSTHRRSVDPTVAARL 418
Query 426 SDVVDDLQDVIQEIRTTIYDLHGASQGI-TRLRQRIDAAVAQFADSGLRTSVQFVGPLSV 484
+D +D L +VIQEIRT I+DLH + + LR I+ A+ +GLR SV+ GPL V
Sbjct 419 ADHIDQLHEVIQEIRTAIFDLHTNDESLRATLRSTINELTAE---TGLRVSVRMSGPLDV 475
Query 485 VDSALADQAEAVVREAVSNAVRHAKASTLTVRVKVDDDLCIEVTDNGRGLPDEFTGSGLT 544
V ++ + AEAVVREAVSN VRHA+A L+V V VDD+L IEV D+G G+PD SGL+
Sbjct 476 VPASTSGDAEAVVREAVSNVVRHARARELSVTVSVDDELVIEVVDDGIGIPDVVARSGLS 535
Query 545 NLRQRAEQAGGEFTLASVPGASGTVLRWSAPL 576
L RA Q+GG F+++++ GT L WSAPL
Sbjct 536 GLANRAAQSGGTFSVSAMD-TGGTRLVWSAPL 566
>gi|226306907|ref|YP_002766867.1| two-component histidine kinase DevS [Rhodococcus erythropolis
PR4]
gi|226186024|dbj|BAH34128.1| two-component histidine kinase DevS [Rhodococcus erythropolis
PR4]
Length=563
Score = 488 bits (1255), Expect = 2e-135, Method: Compositional matrix adjust.
Identities = 270/534 (51%), Positives = 359/534 (68%), Gaps = 3/534 (0%)
Query 45 RDRLDGLVEAMLVVTAGLDLEATLRAIVHSATSLVDARYGAMEVHDRQHRVLHFVYEGID 104
R +DGL+EA+L V+AGLDL+ TLR IV SA +LVDA++GA+ V + FVYEGID
Sbjct 26 RIHVDGLLEALLAVSAGLDLDTTLRTIVKSAIALVDAKFGALGVVGDSEELKQFVYEGID 85
Query 105 EETVRRIGHLPKGLGVIGLLIEDPKPLRLDDVSAHPASIGFPPYHPPMRTFLGVPVRVRD 164
E IG LP+G GV+G LI DPKPLRLDD+S H AS+GFP +HPPM+TFLGVP++ R
Sbjct 86 ETGRELIGDLPRGRGVLGALISDPKPLRLDDLSKHEASVGFPDHHPPMKTFLGVPIQTRG 145
Query 165 ESFGTLYLTDKTNGQPFSDDDEVLVQALAAAAGIAVANARLYQQAKARQSWIEATRDIAT 224
+ FG LYLT+KTNG+ F+ DE++V ALA+AA IA+ N++LY K +Q W+ AT ++ T
Sbjct 146 QVFGNLYLTEKTNGRAFTAHDEMIVLALASAASIAIDNSQLYALTKMKQEWLLATGEVTT 205
Query 225 ELLSGTEPATVFRLVAAEALKLTAADAALVAVPVDEDMPAADVGELLVIETVGSAVASIV 284
LL+G + V +L+A ++L LT++D A +AVP D ++ EL+V G ++V
Sbjct 206 ALLAGADALGVLQLIADKSLSLTSSDCAFLAVPPDPELTGVATAELVVTVASGLDSETLV 265
Query 285 GRTIPVAGAVLREVFVNGIPRRVDRVDLE-GLDELADAGPALLLPLRARGTVAGVVVVLS 343
G IP+ + V+ N P + ++ + G E + GPA++LPLR V GV+ VL
Sbjct 266 GHGIPLDFSTSGAVYRNKFPIVTESLEFDPGFGEGHEYGPAIVLPLRDGQQVRGVLAVLK 325
Query 344 QGGPGAFTDEQLEMMAAFADQAALAWQLATSQRRMRELDVLTDRDRIARDLHDHVIQRLF 403
G + +QL M+AFADQ A+A +LA +QRRM ELD+L DRDRIARDLHDHVIQR+F
Sbjct 326 LRGAEQYGADQLASMSAFADQGAVALRLADNQRRMAELDILADRDRIARDLHDHVIQRIF 385
Query 404 AIGLALQGAVPHERNPEVQQRLSDVVDDLQDVIQEIRTTIYDLHGASQGITRLRQRIDAA 463
A+GL++QG + R PEV QRLS +DDLQD+IQ+IR I+DLH G LR R++
Sbjct 386 AVGLSVQGTLQRTRAPEVHQRLSGTIDDLQDIIQDIRRAIFDLHATEDGAPSLRSRLNQV 445
Query 464 VAQF-ADSGLRTSVQFVGPLSVVDSALADQAEAVVREAVSNAVRHAKASTLTVRVKVDDD 522
VA+ AD+ LR +VQ GPLSVVD +L +QAEAVVREA+SN VRHA+AST+ + + V D
Sbjct 446 VAETSADTDLRVTVQVRGPLSVVDPSLGEQAEAVVREALSNVVRHAQASTVAIVIDVHDS 505
Query 523 LCIEVTDNGRGLPDEFTGSGLTNLRQRAEQAGGEFTLASVPGASGTVLRWSAPL 576
L + + D+G GLP GL NL +RA GG F S G GT L WS PL
Sbjct 506 LTVTIADDGIGLPPGAHRRGLKNLCERAFALGGTFDAQSTDGG-GTTLVWSVPL 558
>gi|258652223|ref|YP_003201379.1| GAF sensor signal transduction histidine kinase [Nakamurella
multipartita DSM 44233]
gi|258555448|gb|ACV78390.1| GAF sensor signal transduction histidine kinase [Nakamurella
multipartita DSM 44233]
Length=595
Score = 486 bits (1251), Expect = 4e-135, Method: Compositional matrix adjust.
Identities = 282/557 (51%), Positives = 381/557 (69%), Gaps = 6/557 (1%)
Query 22 LSQLRLHELLVEVQDRVEQIV-EGRDRLDGLVEAMLVVTAGLDLEATLRAIVHSATSLVD 80
LSQ RL ELL EV DRVE IV + R+R+D L++A+L V++GLD + TLR IV +A LVD
Sbjct 42 LSQERLRELLDEVGDRVEGIVSDTRERMDALLDAVLAVSSGLDQDVTLRQIVQAAIELVD 101
Query 81 ARYGAMEVHDRQHRVLHFVYEGIDEETVRRIGHLPKGLGVIGLLIEDPKPLRLDDVSAHP 140
AR+GA+ V + FV+ GID++T IG LP G GV+G++IE+ KPLRL D+S HP
Sbjct 102 ARFGALGVLGEGGMLSKFVHVGIDDQTRELIGPLPTGHGVLGVVIEENKPLRLADLSQHP 161
Query 141 ASIGFPPYHPPMRTFLGVPVRVRDESFGTLYLTDKTNGQPFSDDDEVLVQALAAAAGIAV 200
SIGFPP+HPPMRTFLGVPVR R E+FG LYLT+K NG+ F+ DDEV+V ALA AAGIA+
Sbjct 162 MSIGFPPHHPPMRTFLGVPVRARGETFGRLYLTEKRNGEEFTFDDEVVVSALAGAAGIAI 221
Query 201 ANARLYQQAKARQSWIEATRDIATELLSGTEPATVFRLVAAEALKLTAADAALVAVPVDE 260
NARLY+ A+ RQ+W+EAT ++ +LL G++ RL+A+ A +LT AD ++A+PV+
Sbjct 222 DNARLYEAARQRQAWLEATGEVTAQLLGGSDTEEALRLIASRARELTKADHTMIALPVEP 281
Query 261 DMPAADVGELLVIETVGSAVASIVGRTIPVAGAVLREVFVNGIPRRVDRVDLEGLDELAD 320
AA+ GEL++ +VG + GR +PVAG+ + VF++ +PR V R+D D
Sbjct 282 ADGAAEPGELVIAVSVGLDSVELTGRRVPVAGSTMGTVFLDRLPRNVLRLD---FDLTGQ 338
Query 321 AGPALLLPLRARGTVAGVVVVLSQGGPGAFTDEQLEMMAAFADQAALAWQLATSQRRMRE 380
GPA++LPL ++GV++ + + G F +++L +++ FADQAALA A SQ RE
Sbjct 339 FGPAMVLPLGTGEQISGVLLTVRRPGSDQFDEQELNLVSTFADQAALALDRAESQLARRE 398
Query 381 LDVLTDRDRIARDLHDHVIQRLFAIGLALQGAVPHERNPEVQQRLSDVVDDLQDVIQEIR 440
++VL DRDRIARDLHDHVIQRLFAIGL +Q E++P RL+D +D L DVIQEIR
Sbjct 399 MEVLEDRDRIARDLHDHVIQRLFAIGLGMQSTHRREKSPHQAARLADHIDQLHDVIQEIR 458
Query 441 TTIYDLHGASQGITRLRQRIDAAVAQF-ADSGLRTSVQFVGPLSVVDSALADQAEAVVRE 499
T I+DL LR ++ ++ D+ LRT+V+ GPL V+ LA +A +RE
Sbjct 459 TAIFDLQAGPAQEPGLRSALNQVISDLTGDAALRTTVRMSGPLDVIPPDLAQDVQAALRE 518
Query 500 AVSNAVRHAKASTLTVRVKVDDDLCIEVTDNGRGLPDEFTGSGLTNLRQRAEQAGGEFTL 559
AVSNAVRHA+A+ L + V V+DDL ++VTDNG GLP+ SGL NL +RA AGG ++
Sbjct 519 AVSNAVRHAQATELIITVSVEDDLVMDVTDNGVGLPETVARSGLHNLGRRAAAAGGALSV 578
Query 560 ASVPGASGTVLRWSAPL 576
P A GT L W+APL
Sbjct 579 TRPP-AGGTRLIWTAPL 594
>gi|300787342|ref|YP_003767633.1| two-component system sensor kinase [Amycolatopsis mediterranei
U32]
gi|299796856|gb|ADJ47231.1| two-component system sensor kinase [Amycolatopsis mediterranei
U32]
gi|340528850|gb|AEK44055.1| two-component system sensor kinase [Amycolatopsis mediterranei
S699]
Length=583
Score = 474 bits (1221), Expect = 1e-131, Method: Compositional matrix adjust.
Identities = 290/571 (51%), Positives = 393/571 (69%), Gaps = 14/571 (2%)
Query 16 RPLRHTLSQLRLHELLVEVQDRVEQIVEGRDRLDGLVEAMLVVTAGLDLEATLRAIVHSA 75
R + TLS LRL E+L ++QDR+E ++ RD++DGL++A+L V +GL+L+ TLR IV +A
Sbjct 18 RRMAGTLSGLRLREVLRDLQDRIELLIGTRDKMDGLLDAVLAVASGLELDTTLRRIVLAA 77
Query 76 TSLVDARYGAMEVHDRQHRVLHFVYEGIDEETVRRIGHLPKGLGVIGLLIEDPKPLRLDD 135
L +A+YGA+ V + F+Y GI++ET R IG LP G GV+G++I++ KPLR+++
Sbjct 78 IELGEAKYGALGVLADDGSMSEFIYVGIEDETRRLIGDLPTGHGVLGVVIDEAKPLRMEE 137
Query 136 VSAHPASIGFPPYHPPMRTFLGVPVRVRDESFGTLYLTDKTNGQPFSDDDEVLVQALAAA 195
+S+HPAS+GFP +HPPM +FLGVPVRVRDE FG LYLT+K NG+PF+DDDEV+VQALAAA
Sbjct 138 ISSHPASVGFPAHHPPMHSFLGVPVRVRDEVFGRLYLTEKKNGEPFTDDDEVVVQALAAA 197
Query 196 AGIAVANARLYQQAKARQSWIEATRDIATELLSGTEPATVFRLVAAEALKLTAADAALVA 255
AGIA+ NA LY+QA+ RQ W+ AT ++ TELL GT+PA L+A+ AL+LT +D ++A
Sbjct 198 AGIAIENAHLYEQARVRQQWLAATSEVTTELLGGTDPAEALNLIASRALELTGSDVTMLA 257
Query 256 VPVDEDM-----PAADVGELLVIETVGSAVASIVGRTIPVAGAVLREVFVNGIPRRVDRV 310
+P + DV +L V + G+ A + G I + +V V+ + PR V +
Sbjct 258 LPNSGRLDVDEDWGDDVDDLTVTVSAGTRAAELSGMHIGLEESVPGAVYQDRTPRNVGEL 317
Query 311 DLEGLDELADAGPALLLPLRARGTVAGVVVVLSQGGPGAFTDEQLEMMAAFADQAALAWQ 370
L GPAL++PLRA GV++ Q G G+F QL ++A+FADQAALA Q
Sbjct 318 RLPD----HRFGPALVVPLRAGDRTTGVLIAARQTGAGSFESAQLPVLASFADQAALALQ 373
Query 371 LATSQRRMRELDVLTDRDRIARDLHDHVIQRLFAIGLALQGAVPHERNPEVQQRLSDVVD 430
LA QR RELDVL DRDRIARDLHDHVIQRLFA+GL++Q ++PE+Q+RL D ++
Sbjct 374 LAAQQRAARELDVLGDRDRIARDLHDHVIQRLFAVGLSMQSTQRRTKSPELQKRLGDSIE 433
Query 431 DLQDVIQEIRTTIYDLHGASQGIT--RLRQRIDAAVAQFADSG-LRTSVQFVGPLSVVDS 487
+ +++QEIRT I+DLHG + G T RLR R+ A+A+ D + +V G + V +
Sbjct 434 QMHEIVQEIRTAIFDLHGGAAGETGLRLRHRLHDAIAELTDDAPVHPTVSMSGSIDTVPA 493
Query 488 ALADQAEAVVREAVSNAVRHAKASTLTVRVKVDDD-LCIEVTDNGRGLPDEFTGSGLTNL 546
LA+ AEAVVREAVSNAVRHA+ASTL+V V V DD L I V D+GRGLP++ + SGL NL
Sbjct 494 QLAEHAEAVVREAVSNAVRHAEASTLSVSVAVKDDVLRIVVADDGRGLPEDVSPSGLGNL 553
Query 547 RQRAEQAGGEFTLASVPGASGTVLRWSAPLS 577
RAE GG FTL P G + WSAP+S
Sbjct 554 GDRAEAVGGAFTLGRGPDG-GVKVEWSAPVS 583
>gi|296394764|ref|YP_003659648.1| GAF sensor signal transduction histidine kinase [Segniliparus
rotundus DSM 44985]
gi|296181911|gb|ADG98817.1| GAF sensor signal transduction histidine kinase [Segniliparus
rotundus DSM 44985]
Length=561
Score = 457 bits (1175), Expect = 3e-126, Method: Compositional matrix adjust.
Identities = 274/561 (49%), Positives = 362/561 (65%), Gaps = 11/561 (1%)
Query 22 LSQLRLHELLVEVQDRVEQIVEG-RDRLDGLVEAMLVVTAGLDLEATLRAIVHSATSLVD 80
L QL+L ELL EVQ+R+EQIV R+R++GL EA++ V++GL+ + TLR IV +A LV
Sbjct 5 LGQLQLRELLAEVQERIEQIVANTRNRMEGLFEAVVAVSSGLEFDLTLRQIVRAAIKLVG 64
Query 81 ARYGAMEVHDRQHRVLHFVYEGIDEETVRRIGHLPKGLGVIGLLIEDPKPLRLDDVSAHP 140
A +GA+ V + FV+EGIDEE + IG LP G G++G + E K RL D++AHP
Sbjct 65 AEHGALGVLGPDGMLTEFVHEGIDEEARKLIGPLPTGRGMLGAMAEGSKTQRLVDIAAHP 124
Query 141 ASIGFPPYHPPMRTFLGVPVRVRDESFGTLYLTDKTNGQPFSDDDEVLVQALAAAAGIAV 200
ASIGFP HP M TFLGVPV+VR E FG LYLT K +GQ F+ DDEV+V+ALA AAGIAV
Sbjct 125 ASIGFPANHPSMSTFLGVPVKVRGEVFGRLYLTGKKDGQQFTKDDEVVVRALAVAAGIAV 184
Query 201 ANARLYQQAKARQSWIEATRDIATELLSGTEPATVFRLVAAEALKLTAADAALVAVPVDE 260
NARLY++A+ RQ + A+ ++ ELL GT PA V RL+A+ A +L AD AL+A+P
Sbjct 185 ENARLYEEARRRQQQLRASAEVTAELLGGTAPAQVLRLIASRAAELVDADHALIALPRGA 244
Query 261 DMPAADVGELLVIETVGSAVASIVGRTIPVAGAVLREVFVNGIPRRVDRVDLEGLD-ELA 319
P A EL V +G + G TIPV +V VF + PR V + L D ++
Sbjct 245 AQP-AHTAELAVAVHIGPCAHEMTGMTIPVDRSVPGAVFCDRTPRNVPELALGLPDGKVV 303
Query 320 DAGPALLLPLRARGTVAGVVVVLSQGGPGAFTDEQLEMMAAFADQAALAWQLATSQRRMR 379
GPAL LPLRA + AGV++++ G F EQL++ A+FA+QAALA + A +
Sbjct 304 TLGPALALPLRAGESTAGVLLLIRDAGGAGFDMEQLDIGASFAEQAALALEQAEIRSAKH 363
Query 380 ELDVLTDRDRIARDLHDHVIQRLFAIGLALQGAVPHER---NPEVQQRLSDVVDDLQDVI 436
EL++L DRDRIARDLHDHVIQRLF IGL +Q H R P V +RL++ +D + +VI
Sbjct 364 ELEMLADRDRIARDLHDHVIQRLFVIGLGMQST--HRRAAKTPAVAERLTEHIDRIHEVI 421
Query 437 QEIRTTIYDLHGASQGITRLRQRIDAAVAQF-ADSGLRTSVQFVGPLSVVDSALADQAEA 495
+EIRT I+DLH A G+ LR + A+A+ DS LR +V+ GPL VV +A AEA
Sbjct 422 EEIRTAIFDLHTAGDGVA-LRVVLHKAIAELTGDSALRVAVRMAGPLDVVPEEIAVHAEA 480
Query 496 VVREAVSNAVRHAKASTLTVRVKVDDDLCIEVTDNGRGLPDEFTGSGLTNLRQRAEQAGG 555
VVREAV+N +RHA A+ L++ V V D I+V DNG+G+P+ SGL NL RA G
Sbjct 481 VVREAVTNVLRHAGATELSITVTVGGDFVIDVADNGKGVPEVVARSGLHNLADRASACCG 540
Query 556 EFTLASVPGASGTVLRWSAPL 576
+ + GT L W+APL
Sbjct 541 SLAVTRLQ-TGGTRLVWTAPL 560
>gi|72163445|ref|YP_291102.1| GAF:ATP-binding protein [Thermobifida fusca YX]
gi|71917177|gb|AAZ57079.1| GAF:ATP-binding region, ATPase-like [Thermobifida fusca YX]
Length=572
Score = 412 bits (1059), Expect = 9e-113, Method: Compositional matrix adjust.
Identities = 250/567 (45%), Positives = 346/567 (62%), Gaps = 24/567 (4%)
Query 24 QLRLHELLVEVQDRVEQIVEGRDRLDGLVEAMLVVTAGLDLEATLRAIVHSATSLVDARY 83
Q+RL ELL E+Q R+ ++ RDR+ L++A++ + +GLDLE+TLR IV +A LVDARY
Sbjct 17 QMRLDELLSELQVRINAVMLVRDRVRSLLDAVVSIGSGLDLESTLRRIVSTAMDLVDARY 76
Query 84 GAMEVHDRQHRVLHFVYEGIDEETVRRIGHLPKGLGVIGLLIEDPKPLRLDDVSAHPASI 143
GAM V + F+ G+ +E + + H P+G G++G+LI++PK LRL +S HP S
Sbjct 77 GAMGVIGPGGELEQFIPLGMSDEEIAAVEHWPEGRGLLGILIKEPKTLRLSCISEHPESA 136
Query 144 GFPPYHPPMRTFLGVPVRVRDESFGTLYLTDKTNGQPFSDDDEVLVQALAAAAGIAVANA 203
GFPP HPPMRTFLGVP+RVR+E FG LYLT+K N F ++DE +V ALA AAGIA+ NA
Sbjct 137 GFPPGHPPMRTFLGVPIRVRNEVFGNLYLTEKRNNAVFDEEDEAIVTALATAAGIAIENA 196
Query 204 RLYQQAKARQSWIEATRDIATELLSGTEPATVFRLVAAEALKLTAADAALVAVPVDEDMP 263
RLY++ + R++W++A+ +I T LLSGT P V LVA +A + ADA LVA+ P
Sbjct 197 RLYEETRRRETWLDASDEITTRLLSGTAPREVLHLVAKKARHM--ADADLVAIAT----P 250
Query 264 AADVGELLVIETVGSAVASIVGRTIPVAGAVLREVFVNGIPRRVDRVDLEGLDELA---- 319
D EL+V G + + GR+ PV G++ F R D + E E A
Sbjct 251 DRDEEELVVRIADGPDASVVRGRSTPVEGSLTGRAF-----RGADPIITELARESATSPT 305
Query 320 -----DAGPALLLPLRARGTVAGVVVVLSQGGPGAFTDEQLEMMAAFADQAALAWQLATS 374
D GP +L+P A + GV+++ + G F ++M+ AFA AA+ +LA +
Sbjct 306 LLHGLDIGPVVLVPFGAPDSRRGVLILGKRAGRLPFPMPTVQMLHAFAGHAAVTLELAEA 365
Query 375 QRRMRELDVLTDRDRIARDLHDHVIQRLFAIGLALQGAVPHERNPEVQQRLSDVVDDLQD 434
+R L VL DRDRIA+DLHD VIQRLFAI ++L +V + V QR+ VDDL D
Sbjct 366 RRHAERLIVLEDRDRIAKDLHDVVIQRLFAIAMSLMSSVRRIEDDTVAQRIQQAVDDLDD 425
Query 435 VIQEIRTTIYDL-HGASQGITRLRQRIDAAVAQFADS-GLRTSVQFVGPL-SVVDSALAD 491
I++IR+TI+ L H G LR RI V +S G V+ GP+ S V ++A+
Sbjct 426 TIRQIRSTIFALQHNTEGGPAWLRSRILDVVGAATESLGFSPGVRLDGPIDSAVPDSIAE 485
Query 492 QAEAVVREAVSNAVRHAKASTLTVRVKVDDDLCIEVTDNGRGLPDEFTGSGLTNLRQRAE 551
AV+REA+SN RHA+AS + V+VD + + VTD+G GLP++ SGL NL +RAE
Sbjct 486 HVLAVLREALSNVARHARASQADIVVQVDSHVTLTVTDDGVGLPEQGRRSGLRNLAERAE 545
Query 552 QAGGEFTLASVPGASGTVLRWSAPLSQ 578
GG F A P GT+LRW PL +
Sbjct 546 SLGGSFEAARRP-EGGTMLRWQVPLPR 571
>gi|240171513|ref|ZP_04750172.1| two-component sensor histidine kinase [Mycobacterium kansasii
ATCC 12478]
Length=549
Score = 407 bits (1047), Expect = 2e-111, Method: Compositional matrix adjust.
Identities = 236/545 (44%), Positives = 341/545 (63%), Gaps = 7/545 (1%)
Query 37 RVEQIVEGRDRLDGLVEAMLVVTAGLDLEATLRAIVHSATSLVDARYGAMEVHDRQHRVL 96
++++++ RD++ L+ ++ + + LDL+ TLR IV +A L A YGA+ V D + +L
Sbjct 4 QLDELLAARDQMAQLLRVIVEIGSDLDLDGTLRRIVTAARELTAAPYGALAVRDPEGTLL 63
Query 97 HFVYEGIDEETVRRIGHLPKGLGVIGLLIEDPKPLRLDDVSAHPASIGFPPYHPPMRTFL 156
F++EGID E RRIGHLP G GV+G+ + + LRLDD++AHPA+ GFP +HPPMR FL
Sbjct 64 SFIHEGIDAEMARRIGHLPVGKGVLGVSLVETPALRLDDLTAHPAACGFPEHHPPMRAFL 123
Query 157 GVPVRVRDESFGTLYLTDKTNGQPFSDDDEVLVQALAAAAGIAVANARLYQQAKARQSWI 216
GVP+ +R FG LYLT G+ FS+ DE L +ALA AAG+A+ NA++ ++ + W+
Sbjct 124 GVPIMIRGTVFGHLYLTHVDPGRVFSESDEFLARALAFAAGVAIDNAQVLERERTAVKWM 183
Query 217 EATRDIATELLSGTEPA-TVFRLVAAEALKLTAADAALVAVPVDEDMPAADVGELLVIET 275
EA+R+I T LL+ EP RL+A +A LT A+ A+V VP+D D P ++ L+V
Sbjct 184 EASREITTALLTSAEPQRRPLRLIAEKACALTDAEQAIVLVPLDADQPPDEIDTLVVSAA 243
Query 276 VGSAVASIVGRTIPVAGAVLREVFVNGIPRRVDRVD--LEGLDELADAGPALLLPLRARG 333
VG A +VG+ +PV G+ VF +G P + + + ++A A+L+PLRA
Sbjct 244 VGRHAAEVVGQRVPVDGSTTGTVFRSGQPLITEAFNHRIPAFTDVAQRS-AILMPLRAHD 302
Query 334 TVAGVVVVLSQGGPGAFTDEQLEMMAAFADQAALAWQLATSQRRMRELDVLTDRDRIARD 393
VAGV+ + F +++++ FA AA+A LA+ + R+L +L +R+RIA D
Sbjct 303 HVAGVIAIARGADKPPFDVSYVDLVSNFATHAAIALMLASGREDARQLTILAERERIAHD 362
Query 394 LHDHVIQRLFAIGLALQGAVPHERNPEVQQRLSDVVDDLQDVIQEIRTTIYDLHGASQGI 453
LHDHVIQRLFA G+ LQG + R+PEV RLS +DDLQ +I+EIRT I+ L +
Sbjct 363 LHDHVIQRLFATGMDLQGTLARARSPEVIGRLSRTLDDLQTIIEEIRTAIFQLKAPLERD 422
Query 454 TRLRQRIDAAVAQFADS-GLRTSVQFVGPLSVVDSALADQAEAVVREAVSNAVRHAKAST 512
R RI A VA + + T+VQ GP++ V LAD AEAV EAVSNA+RH+ A+
Sbjct 423 GGFRHRIQAVVADLTEHRDIVTTVQIDGPMAAVGDELADHAEAVTTEAVSNALRHSGATQ 482
Query 513 LTVRVKVDDDLCIEVTDNGRGLPDEFT-GSGLTNLRQRAEQAGGEFTLASVPGASGTVLR 571
LT+ V V D +++ DNG GLP + + SGL N++ RAEQ GG + S P GT +
Sbjct 483 LTIEVGVADMFSLDIVDNGCGLPADISRRSGLANMKHRAEQLGGSCEINSAPDG-GTRVH 541
Query 572 WSAPL 576
W+APL
Sbjct 542 WTAPL 546
>gi|296171252|ref|ZP_06852656.1| GAF family protein [Mycobacterium parascrofulaceum ATCC BAA-614]
gi|295894220|gb|EFG73977.1| GAF family protein [Mycobacterium parascrofulaceum ATCC BAA-614]
Length=569
Score = 398 bits (1023), Expect = 1e-108, Method: Compositional matrix adjust.
Identities = 226/557 (41%), Positives = 348/557 (63%), Gaps = 7/557 (1%)
Query 25 LRLHELLVEVQDRVEQIVEGRDRLDGLVEAMLVVTAGLDLEATLRAIVHSATSLVDARYG 84
LR + L+ + ++++++V R ++ L++ + + + L+L+A L IV +A + ARYG
Sbjct 12 LRQPDFLIRMHEQLDELVAERQQMGQLLQVAIEIGSDLELDAILHRIVAAAIGMTGARYG 71
Query 85 AMEVHDRQHRVLHFVYEGIDEETVRRIGHLPKGLGVIGLLIEDPKPLRLDDVSAHPASIG 144
A+ V + + FV+ G+D +TV +GHLP G GV+G L + +PLRL ++ HP+++G
Sbjct 72 AIGVWGPEGTLTSFVHSGMDPDTVALVGHLPVGKGVLGALRDRTEPLRLSRLTDHPSAVG 131
Query 145 FPPYHPPMRTFLGVPVRVRDESFGTLYLTDKTNGQPFSDDDEVLVQALAAAAGIAVANAR 204
FP +HPPM+ FLG+PV +R +G+LY+TD G+ F + DE+ V+ALA+AA +A+ NAR
Sbjct 132 FPEHHPPMQAFLGMPVIIRGAVYGSLYVTDDRPGRGFCEADEITVRALASAASVAIDNAR 191
Query 205 LYQQAKARQSWIEATRDIATELLSGTEP-ATVFRLVAAEALKLTAADAALVAVPVDEDMP 263
L+ + +A W +A+R+I+T LLS + P +L+A A +LT A+ A+V VP D D P
Sbjct 192 LFDRVRAGARWTDASREISTALLSESYPDVRPLQLIAERAAELTDAEQAIVLVPADPDQP 251
Query 264 AADVGELLVIETVGSAVASIVGRTIPVAGAVLREVFVNGIPRRVDRVDLEGLDELADAG- 322
+ +V L+V VG ++G+ +PV G+ EVF +G P + + D G
Sbjct 252 SDEVDRLVVSAAVGLHAKRVLGQEVPVRGSTSGEVFRSGRPLLTETFR-RPIPAFTDVGE 310
Query 323 -PALLLPLRARGTVAGVVVVLSQGGPGAFTDEQLEMMAAFADQAALAWQLATSQRRMREL 381
PA+L+PL + GV+VV F ++ L+++ FAD AA+A LAT +R R+L
Sbjct 311 RPAILMPLTSDQHTLGVIVVARNTDASPFDEQHLDLVRDFADHAAIALTLATERRNARDL 370
Query 382 DVLTDRDRIARDLHDHVIQRLFAIGLALQGAVPHERNPEVQQRLSDVVDDLQDVIQEIRT 441
VL DR+RIARDLHD VI R+F +G+ LQG + R+PE+ RL+ VD+LQ VI++IR
Sbjct 371 SVLVDRERIARDLHDQVISRVFTVGMDLQGVLARLRSPELAARLTQSVDELQAVIEDIRR 430
Query 442 TIYDLHGASQGITRLRQRIDAAVAQFADSGLR-TSVQFVGPLSVVDSALADQAEAVVREA 500
T++DL L +R+ A+A+ D G T+++ G ++ V LA+ AEAVVREA
Sbjct 431 TVFDLQQPPARRRSLAERVQDAIARLTDDGNEGTTLRMAGTMTAVGDELAEHAEAVVREA 490
Query 501 VSNAVRHAKASTLTVRVKVDDDLCIEVTDNGRGL-PDEFTGSGLTNLRQRAEQAGGEFTL 559
+ NAVRH++A+T+ V V V D L IE+TD+G G+ P GL + +RA+ GG+ +
Sbjct 491 LGNAVRHSRAATIAVEVTVTDQLLIEITDDGCGVAPGHRRRGGLDRIARRAKDLGGDCAI 550
Query 560 ASVPGASGTVLRWSAPL 576
S PG GT +RWSAPL
Sbjct 551 TSSPGG-GTRVRWSAPL 566
>gi|300787438|ref|YP_003767729.1| two-component system sensor kinase [Amycolatopsis mediterranei
U32]
gi|299796952|gb|ADJ47327.1| two-component system sensor kinase [Amycolatopsis mediterranei
U32]
Length=530
Score = 397 bits (1021), Expect = 2e-108, Method: Compositional matrix adjust.
Identities = 256/545 (47%), Positives = 339/545 (63%), Gaps = 25/545 (4%)
Query 39 EQIVEGRDRLDGLVEAMLVVTAGLDLEATLRAIVHSATSLVDARYGAMEVHDRQHRVLHF 98
E+ GRDR+D L A+L +AGL+LE TL IV +A LV ARYGA+ + D R F
Sbjct 3 EETTSGRDRMDALPAAVLAFSAGLELETTLDRIVTAAAGLVGARYGALALLDEDGRTTAF 62
Query 99 VYEGIDEETVRRIGHLPKGLGVIGLLIEDPKPLRLDDVSAHPASIGFPPYHPPMRTFLGV 158
G+D+ T R+G P G GV+G L+ P+RL AH + G PP HP M FLGV
Sbjct 63 AVTGVDDATRERLGPPPDGHGVLGTLVTGRAPVRL----AHLGNGGLPPEHPSMGAFLGV 118
Query 159 PVRVRDESFGTLYLTDKTNGQPFSDDDEVLVQALAAAAGIAVANARLYQQAKARQSWIEA 218
P+ VR E G LYL+ + QPF+ DDE ALAAAAGIAV NARLY+++++RQ W+EA
Sbjct 119 PLLVRGEILGRLYLSRE---QPFTTDDERATVALAAAAGIAVDNARLYEESRSRQRWLEA 175
Query 219 TRDIATELLSGTEPATVFRLVAAEALKLTAADAALVAVPVDEDMPAADVGELLVIETVGS 278
T +I+ ELL GT+ V L+A A +LT AD AL+A P + P G L+V G
Sbjct 176 TGEISAELLGGTDVREVLHLIATRAAELTGADDALIAWP---ESPG---GPLVVKVCAGP 229
Query 279 AVASIVGRTIPVAGAVLREVFVNGIPRRVDRVDLEGLDELA-DAGPALLLPLRARGTVAG 337
+ GR IP+ G+ V + +PR V + + L D GPAL++ LR+ G+ +G
Sbjct 230 DADVLAGRRIPLDGSTAGAVLRDHVPRSVPSLAFDLAAGLGVDLGPALVVRLRS-GSRSG 288
Query 338 VVVVLSQGGPGA--FTDEQLEMMAAFADQAALAWQLATSQRRMRELDVLTDRDRIARDLH 395
V+L+ G GA F + +L++++AFADQAALA + A SQ RELDV+ DRDRIARDLH
Sbjct 289 GAVLLAIRGRGAARFGEHELQLVSAFADQAALALRDAESQAARRELDVVVDRDRIARDLH 348
Query 396 DHVIQRLFAIGLALQGAVPHERNPEVQQRLSDVVDDLQDVIQEIRTTIYDLH---GASQG 452
DHVIQRLFA+GL ++G +P V RL +D LQDVI+EIR+ I+ LH GA +G
Sbjct 349 DHVIQRLFAVGLGIEGTRRRSDSPAVTSRLIQHIDQLQDVIEEIRSAIFALHAQPGAGRG 408
Query 453 ITRLRQRIDAAVAQ-FADSGLRTSVQFVGPLSVVDSALADQAEAVVREAVSNAVRHAKAS 511
LR R+ A+ ADS +RT+V+ G V + LA+ AEAVVREAV+N +RHA+A+
Sbjct 409 ---LRARLQNAITDGCADSAIRTTVRLSGAFDRVPAGLAEHAEAVVREAVTNVLRHARAA 465
Query 512 TLTVRVKVDDDLCIEVTDNGRGLPDEFTGSGLTNLRQRAEQAGGEFTLASVPGASGTVLR 571
L V V +DDDL +EV+D G G+P+ SGL NL QRA +AGG L P GT L
Sbjct 466 DLAVTVSLDDDLVVEVSDTGIGMPEAVARSGLRNLEQRAAEAGGSLRL-DRPAGGGTCLV 524
Query 572 WSAPL 576
W+ P+
Sbjct 525 WTVPV 529
>gi|296169095|ref|ZP_06850754.1| GAF family protein [Mycobacterium parascrofulaceum ATCC BAA-614]
gi|295896215|gb|EFG75877.1| GAF family protein [Mycobacterium parascrofulaceum ATCC BAA-614]
Length=574
Score = 395 bits (1015), Expect = 1e-107, Method: Compositional matrix adjust.
Identities = 242/581 (42%), Positives = 351/581 (61%), Gaps = 15/581 (2%)
Query 1 MTTGGLVDENDGAAMRPLRHTLSQLRLHELLVEVQDRVEQIVEGRDRLDGLVEAMLVVTA 60
M G+ ++ G+A L R+HE L ++++ RD+++ L+ ++ + A
Sbjct 1 MEAVGVTSDDSGSAFAGLGQRGLVSRMHEQL-------DELLAARDQMEQLLRVIVEIGA 53
Query 61 GLDLEATLRAIVHSATSLVDARYGAMEVHDRQHRVLHFVYEGIDEETVRRIGHLPKGLGV 120
GLDL ATL I+ +A L A YGA+ + D +L FV+EG+D +TV RIG LP G G+
Sbjct 54 GLDLNATLHRIIGAARRLTSAPYGALAIRDPDGNLLSFVHEGMDPDTVSRIGPLPVGKGL 113
Query 121 IGLLIEDPKPLRLDDVSAHPASIGFPPYHPPMRTFLGVPVRVRDESFGTLYLTDKTNGQP 180
+ L + D LR+DD++ HPAS GFP +HPPMR FL VP+ +R+ FG LYLT +
Sbjct 114 LSLSLLDTPALRMDDLTNHPASAGFPEHHPPMRAFLAVPITIRETVFGNLYLTHVDPERV 173
Query 181 FSDDDEVLVQALAAAAGIAVANARLYQQAKARQSWIEATRDIATELLSGTEPA-TVFRLV 239
FS+ DEV +ALA AA +A+ NA+++++ + W+EA+R+I T LLS EP +++
Sbjct 174 FSESDEVAARALAFAAAVAIDNAQVFERERTAVKWMEASREITTALLSRPEPHRRPLQVI 233
Query 240 AAEALKLTAADAALVAVPVDEDMPAADVGELLVIETVGSAVASIVGRTIPVAGAVLREVF 299
A A LT A+ A+V VP D D+P +V L+V VG A +VG+ +PV + VF
Sbjct 234 AESARTLTDAEQAIVLVPADPDLPDDEVDTLVVSAAVGLHAAEVVGQRVPVDASTSGAVF 293
Query 300 VNGIPRRVDRVDLEGLDELADAG--PALLLPLRARGTVAGVVVVLSQGGPGAFTDEQLEM 357
+G P + + + D G PA+L+PLRAR V GV+ + F D L++
Sbjct 294 RSGRPMITETLRYP-IQAFTDVGQRPAILMPLRAREEVVGVIAIARGADEPPFDDSYLDL 352
Query 358 MAAFADQAALAWQLATSQRRMRELDVLTDRDRIARDLHDHVIQRLFAIGLALQGAVPHER 417
++ FA AA+A LA+++ R L +L +R+RIA DLHDHVIQRLFA G+ LQG + R
Sbjct 353 VSDFATHAAIALVLASAREDARRLTILAERERIAHDLHDHVIQRLFAAGMDLQGTLARAR 412
Query 418 NPEVQQRLSDVVDDLQDVIQEIRTTIYDLHGASQGITRLRQRIDAAVAQFA-DSGLRTSV 476
+PEV +RL+ +DDLQ +I+EIRTTI+ L S G + R RI VA D + T+V
Sbjct 413 SPEVAERLNRTLDDLQTIIEEIRTTIFQLKSPS-GKSDFRYRIQQVVADLTEDRDIVTTV 471
Query 477 QFVGPLSVVDSALADQAEAVVREAVSNAVRHAKASTLTVRVKVDDDLCIEVTDNGRGLPD 536
+ GP++ V LAD AEAV EAVSN++RH+ A+ LTV + V D +++ DNG G+PD
Sbjct 472 RMHGPMTAVGGELADHAEAVTAEAVSNSLRHSGATRLTVEISVADMFVLDIVDNGSGIPD 531
Query 537 EFT-GSGLTNLRQRAEQAGGEFTLASVPGASGTVLRWSAPL 576
T SGL N+++RAE+ GG + P GT + W APL
Sbjct 532 GNTRHSGLANMKRRAERLGGACEITG-PPEGGTRVHWVAPL 571
>gi|41409368|ref|NP_962204.1| hypothetical protein MAP3270c [Mycobacterium avium subsp. paratuberculosis
K-10]
gi|41398188|gb|AAS05818.1| hypothetical protein MAP_3270c [Mycobacterium avium subsp. paratuberculosis
K-10]
Length=551
Score = 393 bits (1009), Expect = 5e-107, Method: Compositional matrix adjust.
Identities = 241/547 (45%), Positives = 342/547 (63%), Gaps = 8/547 (1%)
Query 36 DRVEQIVEGRDRLDGLVEAMLVVTAGLDLEATLRAIVHSATSLVDARYGAMEVHDRQHRV 95
+R +++ RD+ + L+ + + AGLDL+ATL I+ +A L A YGA+ V DR +
Sbjct 4 NRFDELAAARDQTEKLLRVIAEIGAGLDLDATLHRIISAARELTSAPYGALAVRDRHANL 63
Query 96 LHFVYEGIDEETVRRIGHLPKGLGVIGLLIEDPKPLRLDDVSAHPASIGFPPYHPPMRTF 155
+ FV+EG+D ETVRRIGH P G G++ L + D LR+DD++AHPA+ GFP +HP MR F
Sbjct 64 ISFVHEGMDAETVRRIGHHPVGKGLLSLSLLDTPALRMDDLTAHPAAAGFPEHHPAMRAF 123
Query 156 LGVPVRVRDESFGTLYLTDKTNGQPFSDDDEVLVQALAAAAGIAVANARLYQQAKARQSW 215
L VP+ +R FG LYLT + FSD DE+ +ALA AA +A+ NA+++++ + W
Sbjct 124 LAVPITIRGAVFGNLYLTHVDEARVFSDADEMAARALAFAAAVAIDNAQVFERERMSVKW 183
Query 216 IEATRDIATELLSGTEPA-TVFRLVAAEALKLTAADAALVAVPVDEDMPA-ADVGELLVI 273
IEA+R+I T LLS TEP +L+A A LT A+ A+V VP D + P +V L+V+
Sbjct 184 IEASREITTALLSRTEPHRRPMQLIAERACALTDAEQAIVLVPADPEQPGNPEVDTLVVL 243
Query 274 ETVGSAVASIVGRTIPVAGAVLREVFVNGIPRRVDRVDLEGLDELADAG--PALLLPLRA 331
VG A ++G+ +PV G+ VF +G P D + DAG PA+++PLRA
Sbjct 244 AAVGLPAADVLGQRVPVRGSTSGAVFKSGEPLITDEFRYP-IQAFTDAGRRPAIVMPLRA 302
Query 332 RGTVAGVVVVLSQGGPGAFTDEQLEMMAAFADQAALAWQLATSQRRMRELDVLTDRDRIA 391
R V GV+ + F + L+++ FA AA+A LA ++ R+L VL +R+RIA
Sbjct 303 RDEVVGVIAIARGTEQPPFDESYLDLVRDFATHAAIALVLAAAREDARQLAVLAERERIA 362
Query 392 RDLHDHVIQRLFAIGLALQGAVPHERNPEVQQRLSDVVDDLQDVIQEIRTTIYDLHGASQ 451
DLHDHVIQRLFA G+ LQG + R+PEV RL+ +DDLQ +I+EIRTTI+ L +
Sbjct 363 HDLHDHVIQRLFAAGMDLQGTLARARSPEVADRLNRTLDDLQTIIEEIRTTIFALRSPAA 422
Query 452 GITRLRQRIDAAVAQFADS-GLRTSVQFVGPLSVVDSALADQAEAVVREAVSNAVRHAKA 510
R RI +A+ ++ L T+V+ GP++ V + LA+ AEAV EAVSNAVRH+ A
Sbjct 423 VAGDFRHRIQRVIAELTENRDLVTTVRMDGPMTAVGAELAEHAEAVTAEAVSNAVRHSGA 482
Query 511 STLTVRVKVDDDLCIEVTDNGRGLPDEFT-GSGLTNLRQRAEQAGGEFTLASVPGASGTV 569
S LTV++ V D ++V DNGRG+ T SGL N+ +RAEQ GG ++S PG GT
Sbjct 483 SRLTVQIGVADMFTLDVIDNGRGIASGNTRRSGLANMTRRAEQLGGSCEISSPPGG-GTR 541
Query 570 LRWSAPL 576
+ W+APL
Sbjct 542 VHWTAPL 548
>gi|288917580|ref|ZP_06411944.1| GAF sensor signal transduction histidine kinase [Frankia sp.
EUN1f]
gi|288350973|gb|EFC85186.1| GAF sensor signal transduction histidine kinase [Frankia sp.
EUN1f]
Length=626
Score = 392 bits (1008), Expect = 7e-107, Method: Compositional matrix adjust.
Identities = 251/563 (45%), Positives = 335/563 (60%), Gaps = 20/563 (3%)
Query 23 SQLRLHELLVEVQDRVEQIVEGRDRLDGLVEAMLVVTAGLDLEATLRAIVHSATSLVDAR 82
+L L EL+V++ +R +++ + RL L+ A V A L LE LR I +A LVDAR
Sbjct 74 GRLELDELMVQLVERAHEVMTTQGRLRSLLRAHRAVAADLSLEVVLRRIAEAACELVDAR 133
Query 83 YGAMEVHDRQHRVLHFVYEGIDEETVRRIGHLPKGLGVIGLLIEDPKPLRLDDVSAHPAS 142
YGA+ V R R+ F++ G+D + VRRIGHLP+G GV+GLL DP+P+RLDD++AH +
Sbjct 134 YGALGVIARDGRMEQFIHVGMDADLVRRIGHLPRGEGVLGLLTADPRPVRLDDIAAHDHA 193
Query 143 IGFPPYHPPMRTFLGVPVRVRDESFGTLYLTDKTNGQPFSDDDEVLVQALAAAAGIAVAN 202
+GFPP HPPMRTFLGVP++VR E FG LYLT+K G+ F+ DE LV ALAA+AG+A+ N
Sbjct 194 VGFPPGHPPMRTFLGVPIKVRSEVFGNLYLTEKRGGRRFTAQDEELVLALAASAGVAIEN 253
Query 203 ARLYQQAKARQSWIEATRDIATELLS-GTEPATVFRLVAAEALKLTAADAALVAVPVDED 261
ARL+ A+ RQ W++A+ DI LL+ G EP L+ A ++ AD A V + DE
Sbjct 254 ARLFGAAQRRQQWLQASADIMRHLLADGAEP---LALIVGRAREVADADLACVLL-ADE- 308
Query 262 MPAADVGELLVIETVGSAVASIVGRTIPVAGAVLREVFVNGIPRRVDRVDLE----GLDE 317
GELL+ G A S+VG+ +P + +G P VD LE GL
Sbjct 309 ----VTGELLIEAADGLAADSLVGQVVPTEVTLAGRSVADGRPVLVDDATLEPGSSGLGA 364
Query 318 LADAGPALLLPLRARGTVAGVVVVLSQGGPGAFTDEQLEMMAAFADQAALAWQLATSQRR 377
+ GP +++PL T G VV+ + G F D L+M A FA +A LATS+
Sbjct 365 VG-IGPIMVIPLVGTQTRPGAVVLARETGGRPFADTDLDMAATFAGHVQVALGLATSRAN 423
Query 378 MRELDVLTDRDRIARDLHDHVIQRLFAIGLALQGAVPHERNPEVQQRLSDVVDDLQDVIQ 437
L VL DRDRIARDLHDHV+QRL+A+ L LQG E RLS VDDL I+
Sbjct 424 RDRLLVLEDRDRIARDLHDHVMQRLYAVALGLQGMAAAEDRAPAAGRLSTYVDDLDATIR 483
Query 438 EIRTTIYDLHG-ASQGITRLRQRIDAAVAQFADS-GLRTSVQFVGPL-SVVDSALADQAE 494
EIR+T+++L G S G +R R+ V + ++ G ++ GPL SV+ D
Sbjct 484 EIRSTVFELRGRRSSGGAGVRARLVEIVEEVGEALGFSPRLRVDGPLDSVLSGKTVDHLL 543
Query 495 AVVREAVSNAVRHAKASTLTVRVKVDDD-LCIEVTDNGRGLPDEFTGSGLTNLRQRAEQA 553
AV RE++SN RHA+AS + V V L EVTD+G GL D SGL NLR RAE+
Sbjct 544 AVARESLSNVARHARASRAELSVTVGQGWLRAEVTDDGVGLGDTSRRSGLDNLRSRAEEL 603
Query 554 GGEFTLASVPGASGTVLRWSAPL 576
GG F +A+ P + GT LRW+ PL
Sbjct 604 GGTFDIAAGP-SGGTRLRWAVPL 625
>gi|256376041|ref|YP_003099701.1| GAF sensor signal transduction histidine kinase [Actinosynnema
mirum DSM 43827]
gi|255920344|gb|ACU35855.1| GAF sensor signal transduction histidine kinase [Actinosynnema
mirum DSM 43827]
Length=566
Score = 392 bits (1007), Expect = 9e-107, Method: Compositional matrix adjust.
Identities = 246/558 (45%), Positives = 357/558 (64%), Gaps = 9/558 (1%)
Query 22 LSQLRLHELLVEVQDRVEQIVEGRDRLDGLVEAMLVVTAGLDLEATLRAIVHSATSLVDA 81
L+ LRL ELL E+++R+ +I RD++ L++A+L V GL+L++TL+ IV +A LV A
Sbjct 14 LAGLRLDELLEEMRERLTEIGSTRDKMQRLLDAVLAVGTGLELDSTLQRIVQAAVDLVGA 73
Query 82 RYGAMEVHDRQHRVLHFVYEGIDEETVRRIGHLPKGLGVIGLLIEDPKPLRLDDVSAHPA 141
RYGA+ V + + FV+ GID++ R+GHLP+G G++GLLI+DP+P+RL D+ AHPA
Sbjct 74 RYGALGVLGNRDDLSEFVHVGIDQDERARMGHLPQGKGLLGLLIKDPRPVRLHDLGAHPA 133
Query 142 SIGFPPYHPPMRTFLGVPVRVRDESFGTLYLTDKTNGQPFSDDDEVLVQALAAAAGIAVA 201
S+G PP HPPM+TFLGVPVRVRDE FG LY+ +K +G F+ DDE+++ ALAAAAG+AV
Sbjct 134 SVGLPPNHPPMKTFLGVPVRVRDEVFGNLYMAEKRDGGDFTPDDEIVLSALAAAAGVAVE 193
Query 202 NARLYQQAKARQSWIEATRDIATELLSGTEPATVFRLVAAEALKLTAADAALVAVPVDED 261
NARL+++++ R+ W+EA ++ ELL G RL++ +L AA +L+ V +E
Sbjct 194 NARLFEKSRMRERWLEAAAEVNAELLGGASAEDALRLISQRTRELAAAAVSLI-VLAEEG 252
Query 262 MPAADVGELLVIETVGSAVASIVGRTIPVAGAVLREVFVNGIPRRVDRVDLEGLDELA-D 320
+ L + G +VG + +V +G+P +R+D GL E + +
Sbjct 253 KNGRRL--LRMASAAGGDTDRLVGGLLDGENTFAHQVLDSGVPALFERLD-GGLGEASLE 309
Query 321 AGPALLLPLRARGTVAGVVVVLSQGGPGAFTDEQLEMMAAFADQAALAWQLATSQRRMRE 380
GP + +PLR V GV++ G F EQ+ ++A+FA QAA+A +LA +QR R
Sbjct 310 LGPGVAVPLRTASQVTGVLLAARDVGAAQFGAEQVPLLASFAAQAAVALELAETQRNRRL 369
Query 381 LDVLTDRDRIARDLHDHVIQRLFAIGLALQGAVPHERNPEVQQRLSDVVDDLQDVIQEIR 440
+DVL DRDRIARDLHDHVIQRLFA G++LQGA+ +P++++R+ + V L + EIR
Sbjct 370 VDVLEDRDRIARDLHDHVIQRLFATGMSLQGALNRVEDPKLRERVDNAVHQLDQTVLEIR 429
Query 441 TTIYDLHGASQGITRLRQRIDAAVAQFAD-SGLRTSVQFVGPL-SVVDSALADQAEAVVR 498
TTI+DL A LR+R+ V+Q + S L +V+ G + + V + + AEAVVR
Sbjct 430 TTIFDLQAADDE-PGLRRRLLDIVSQVTEHSALTPAVRMNGTVDNSVPDHVGEHAEAVVR 488
Query 499 EAVSNAVRHAKASTLTVRVKVDDDLCIEVTDNGRGLPDEFTGSGLTNLRQRAEQAGGEFT 558
E VSNAVRH+ AS LTV ++ D L I V DNG G+P++ SGL NL +RA + GG
Sbjct 489 ELVSNAVRHSGASELTVTIEADRQLTISVVDNGIGMPEKVARSGLRNLDERARRLGGSAV 548
Query 559 LASVPGASGTVLRWSAPL 576
+ + G GT + W PL
Sbjct 549 VEACAGG-GTRVTWQVPL 565
>gi|158313804|ref|YP_001506312.1| GAF sensor signal transduction histidine kinase [Frankia sp.
EAN1pec]
gi|158109209|gb|ABW11406.1| GAF sensor signal transduction histidine kinase [Frankia sp.
EAN1pec]
Length=568
Score = 392 bits (1007), Expect = 1e-106, Method: Compositional matrix adjust.
Identities = 248/564 (44%), Positives = 337/564 (60%), Gaps = 22/564 (3%)
Query 23 SQLRLHELLVEVQDRVEQIVEGRDRLDGLVEAMLVVTAGLDLEATLRAIVHSATSLVDAR 82
+L L EL+ ++ +R +++ + RL GL+ A V A L LE LR I +A LVDAR
Sbjct 16 GRLELDELMAQLVERAHEVMTTQGRLRGLLRAHRAVAADLSLEVVLRRIAEAACELVDAR 75
Query 83 YGAMEVHDRQHRVLHFVYEGIDEETVRRIGHLPKGLGVIGLLIEDPKPLRLDDVSAHPAS 142
YGA+ V R R+ F++ G+D + V RIGHLP+G GV+GLL +P+ +RLDD++AH +
Sbjct 76 YGALGVIARDGRLEQFIHVGMDADLVGRIGHLPRGEGVLGLLTAEPRAVRLDDIAAHEHA 135
Query 143 IGFPPYHPPMRTFLGVPVRVRDESFGTLYLTDKTNGQPFSDDDEVLVQALAAAAGIAVAN 202
+GFPP HPPMRTFLGVP++VR E FG LYLT+K G+ F+ DE LV ALAA+AG+A+ N
Sbjct 136 VGFPPGHPPMRTFLGVPIKVRSEVFGNLYLTEKRGGRRFTAQDEELVLALAASAGVAIEN 195
Query 203 ARLYQQAKARQSWIEATRDIATELLS-GTEPATVFRLVAAEALKLTAADAALVAVPVDED 261
ARL+ A+ RQ W++A+ DI LL+ G EP T L+ A A ++ AD A V
Sbjct 196 ARLFGAAQRRQQWLQASADIMRHLLADGPEPLT---LIVARAREVADADLACVL------ 246
Query 262 MPAADVGELLVIETVGSAVASIVGRTIPVAGAVLREVFVNGIPRRVDRVDLE----GLDE 317
+ ELLV G ++G ++P+AG + G P VD E G
Sbjct 247 LADGATEELLVDAADGPQADRLLGESVPMAGTLAGRAVAAGRPLLVDDAAAEPGVTGFGG 306
Query 318 LADAGPALLLPLRARGTVAGVVVVLSQGGPG-AFTDEQLEMMAAFADQAALAWQLATSQR 376
L D GP +++PL V VVL++G G F D L+M A FA +A LA S+
Sbjct 307 L-DIGPLMVIPLVG-AQVGTGAVVLARGPAGRPFADGDLDMAATFAGHVQVALGLAASRA 364
Query 377 RMRELDVLTDRDRIARDLHDHVIQRLFAIGLALQGAVPHERNPEVQQRLSDVVDDLQDVI 436
L VL DRDRIARDLHDHV+QRL+A+ L LQG E P+ RL+ VDDL I
Sbjct 365 TRDRLLVLEDRDRIARDLHDHVMQRLYAVALGLQGMAAAEERPQSAGRLTTYVDDLDATI 424
Query 437 QEIRTTIYDLHG-ASQGITRLRQRIDAAVAQFADS-GLRTSVQFVGPL-SVVDSALADQA 493
+EIR+T+++L G S G +R R+ V + A++ G ++ GPL + ++ +AD
Sbjct 425 REIRSTVFELRGRRSTGGPGVRARLGEIVEEVAEALGFSPRLRVDGPLDTALEGNIADHL 484
Query 494 EAVVREAVSNAVRHAKASTLTVRVKVDDD-LCIEVTDNGRGLPDEFTGSGLTNLRQRAEQ 552
AV RE++SN RHA+AS + + V V LC EVTD+G GL D SGL NLR RAE+
Sbjct 485 LAVARESLSNVARHARASRVELSVTVGQGWLCAEVTDDGVGLGDTGRRSGLRNLRSRAEE 544
Query 553 AGGEFTLASVPGASGTVLRWSAPL 576
GG F +A P + GT LRW+ PL
Sbjct 545 LGGTFDIAPGP-SGGTRLRWAVPL 567
>gi|336459463|gb|EGO38403.1| histidine kinase,GAF domain-containing protein [Mycobacterium
avium subsp. paratuberculosis S397]
Length=551
Score = 391 bits (1005), Expect = 1e-106, Method: Compositional matrix adjust.
Identities = 241/547 (45%), Positives = 341/547 (63%), Gaps = 8/547 (1%)
Query 36 DRVEQIVEGRDRLDGLVEAMLVVTAGLDLEATLRAIVHSATSLVDARYGAMEVHDRQHRV 95
+R +++ RD+ + L+ + + AGLDL+ATL I+ +A L A YGA+ V DR +
Sbjct 4 NRFDELAAARDQTEKLLRVIAEIGAGLDLDATLHRIISAARELTSAPYGALAVRDRHANL 63
Query 96 LHFVYEGIDEETVRRIGHLPKGLGVIGLLIEDPKPLRLDDVSAHPASIGFPPYHPPMRTF 155
+ FV+EG+D ETVRRIGH P G G++ L + D LR+DD++AHPA+ GFP +HP MR F
Sbjct 64 ISFVHEGMDAETVRRIGHHPVGKGLLSLSLLDTPALRMDDLTAHPAAAGFPEHHPAMRAF 123
Query 156 LGVPVRVRDESFGTLYLTDKTNGQPFSDDDEVLVQALAAAAGIAVANARLYQQAKARQSW 215
L VP+ +R FG LYLT + FSD DE+ +ALA AA +A+ NA+++++ + W
Sbjct 124 LAVPITIRGAVFGNLYLTHVDEARVFSDADEMAARALAFAAAVAIDNAQVFERERMSVKW 183
Query 216 IEATRDIATELLSGTEPA-TVFRLVAAEALKLTAADAALVAVPVDEDMPA-ADVGELLVI 273
IEA+R+I T LLS TEP +L+A A LT A+ A+V VP D + P +V L+V
Sbjct 184 IEASREITTALLSRTEPHRRPMQLIAERACALTDAEQAIVLVPADPEQPGNPEVDTLVVS 243
Query 274 ETVGSAVASIVGRTIPVAGAVLREVFVNGIPRRVDRVDLEGLDELADAG--PALLLPLRA 331
VG A ++G+ +PV G+ VF +G P D + DAG PA+++PLRA
Sbjct 244 AAVGLPAADVLGQRVPVRGSTSGAVFKSGEPLITDEFRYP-IQAFTDAGRRPAIVMPLRA 302
Query 332 RGTVAGVVVVLSQGGPGAFTDEQLEMMAAFADQAALAWQLATSQRRMRELDVLTDRDRIA 391
R V GV+ + F + L+++ FA AA+A LA ++ R+L VL +R+RIA
Sbjct 303 RDEVVGVIAIARGTEQPPFDESYLDLVRDFATHAAIALVLAAAREDARQLAVLAERERIA 362
Query 392 RDLHDHVIQRLFAIGLALQGAVPHERNPEVQQRLSDVVDDLQDVIQEIRTTIYDLHGASQ 451
DLHDHVIQRLFA G+ LQG + R+PEV RL+ +DDLQ +I+EIRTTI+ L +
Sbjct 363 HDLHDHVIQRLFAAGMDLQGTLARARSPEVADRLNRTLDDLQTIIEEIRTTIFALRSPAA 422
Query 452 GITRLRQRIDAAVAQFADS-GLRTSVQFVGPLSVVDSALADQAEAVVREAVSNAVRHAKA 510
R RI +A+ ++ L T+V+ GP++ V + LA+ AEAV EAVSNAVRH+ A
Sbjct 423 VAGDFRHRIQRVIAELTENRDLVTTVRMDGPMTAVGAELAEHAEAVTAEAVSNAVRHSGA 482
Query 511 STLTVRVKVDDDLCIEVTDNGRGLPDEFT-GSGLTNLRQRAEQAGGEFTLASVPGASGTV 569
S LTV++ V D ++V DNGRG+ T SGL N+ +RAEQ GG ++S PG GT
Sbjct 483 SRLTVQIGVADMFTLDVIDNGRGIASGNTRRSGLANMTRRAEQLGGSCEISSPPGG-GTR 541
Query 570 LRWSAPL 576
+ W+APL
Sbjct 542 VHWTAPL 548
>gi|183983462|ref|YP_001851753.1| two-component sensor histidine kinase [Mycobacterium marinum
M]
gi|183176788|gb|ACC41898.1| two-component sensor histidine kinase [Mycobacterium marinum
M]
Length=549
Score = 391 bits (1004), Expect = 2e-106, Method: Compositional matrix adjust.
Identities = 225/545 (42%), Positives = 335/545 (62%), Gaps = 7/545 (1%)
Query 37 RVEQIVEGRDRLDGLVEAMLVVTAGLDLEATLRAIVHSATSLVDARYGAMEVHDRQHRVL 96
++++++ RD+++ L+ ++ + + LDL+ATLR IV +A L A YGA+ V D + ++
Sbjct 4 QLDELLAARDQMEQLLRVIVEIGSDLDLDATLRRIVLAARELTSAPYGALAVRDPEGTLI 63
Query 97 HFVYEGIDEETVRRIGHLPKGLGVIGLLIEDPKPLRLDDVSAHPASIGFPPYHPPMRTFL 156
F++ G+D++ RRIGHLP G GV+G+ + + LRLDD++ HPA+ GFP +HPPMR FL
Sbjct 64 RFIHAGMDDDVARRIGHLPVGKGVLGVSLVETPALRLDDLTMHPAACGFPEHHPPMRAFL 123
Query 157 GVPVRVRDESFGTLYLTDKTNGQPFSDDDEVLVQALAAAAGIAVANARLYQQAKARQSWI 216
VP+ +R FG+LYLT G+ FS+ DE +ALA AAG+A+ NA+++++ + W+
Sbjct 124 AVPITIRGTVFGSLYLTHVDPGRKFSESDEFAARALAFAAGVAIDNAQVFERERTAVKWM 183
Query 217 EATRDIATELLSGTEP-ATVFRLVAAEALKLTAADAALVAVPVDEDMPAADVGELLVIET 275
EA+R+I T L+S TE +L+A A LT A+ A+V VPV+ D+ ++ L+V
Sbjct 184 EASREITTALMSSTESRREPLQLIAQRACTLTDAEQAIVLVPVESDLATDEIDTLVVSAA 243
Query 276 VGSAVASIVGRTIPVAGAVLREVFVNGIP--RRVDRVDLEGLDELADAGPALLLPLRARG 333
VG +VG+ +PV G+ +VF +G P +E ++A A+++PL A
Sbjct 244 VGLHAEEVVGQQVPVRGSTCGDVFRSGEPLISEAFSYPIEAFTDVAQRS-AIVMPLSAHE 302
Query 334 TVAGVVVVLSQGGPGAFTDEQLEMMAAFADQAALAWQLATSQRRMRELDVLTDRDRIARD 393
VAGV+ V F L++++ FA AA+A LA+ + R+L +L +R+RIA D
Sbjct 303 KVAGVIAVARGADQPPFDARCLDLVSQFATHAAIALLLASGREDARQLTILAERERIAHD 362
Query 394 LHDHVIQRLFAIGLALQGAVPHERNPEVQQRLSDVVDDLQDVIQEIRTTIYDLHGASQGI 453
LHDHVIQRLFA G+ LQG + R+PEV RL+ VDDLQ +I+EIR+TI+ L S
Sbjct 363 LHDHVIQRLFASGMDLQGTLARARSPEVIDRLNRTVDDLQTIIEEIRSTIFQLKSPSGRD 422
Query 454 TRLRQRIDAAVAQFADS-GLRTSVQFVGPLSVVDSALADQAEAVVREAVSNAVRHAKAST 512
RQRI VA + + T++ GP+S V LAD AEAV EA+SNAVRH+ A
Sbjct 423 GGFRQRIQQVVADLTEHRDVVTTIHMHGPMSAVQGELADHAEAVATEAISNAVRHSGAGR 482
Query 513 LTVRVKVDDDLCIEVTDNGRGL-PDEFTGSGLTNLRQRAEQAGGEFTLASVPGASGTVLR 571
+T+ V V D +EV D+G G+ PD SGL N+R RAE+ GG + + P GT +
Sbjct 483 VTLDVSVGDMFSLEVVDDGCGISPDVSRRSGLANMRSRAEKLGGTCGI-TTPTEGGTRIS 541
Query 572 WSAPL 576
W+ P
Sbjct 542 WTVPF 546
>gi|254776534|ref|ZP_05218050.1| hypothetical protein MaviaA2_17954 [Mycobacterium avium subsp.
avium ATCC 25291]
Length=551
Score = 389 bits (1000), Expect = 6e-106, Method: Compositional matrix adjust.
Identities = 241/547 (45%), Positives = 340/547 (63%), Gaps = 8/547 (1%)
Query 36 DRVEQIVEGRDRLDGLVEAMLVVTAGLDLEATLRAIVHSATSLVDARYGAMEVHDRQHRV 95
+R +++ RD+ + L+ + + AGLDL+ATL I+ +A L A YGA+ V DR +
Sbjct 4 NRFDELAAARDQTEKLLRVIAEIGAGLDLDATLHRIISAARELTSAPYGALAVRDRHANL 63
Query 96 LHFVYEGIDEETVRRIGHLPKGLGVIGLLIEDPKPLRLDDVSAHPASIGFPPYHPPMRTF 155
+ FV+EG+D ETVRRIGH P G G++ L + D LR+DD++AHPA+ GFP +HP MR F
Sbjct 64 ISFVHEGMDAETVRRIGHHPVGKGLLSLSLLDTPALRMDDLTAHPAAAGFPEHHPAMRAF 123
Query 156 LGVPVRVRDESFGTLYLTDKTNGQPFSDDDEVLVQALAAAAGIAVANARLYQQAKARQSW 215
L VP+ +R FG LYLT + FSD DE+ +ALA AA +A+ NA+++++ + W
Sbjct 124 LAVPITIRGAVFGNLYLTHVDEARVFSDADEMAARALAFAAAVAIDNAQVFERERMSVKW 183
Query 216 IEATRDIATELLSGTEPA-TVFRLVAAEALKLTAADAALVAVPVDEDMPA-ADVGELLVI 273
IEA+R+I T LLS TEP +L+A A LT A+ A+V VP D P +V L+V
Sbjct 184 IEASREITTALLSRTEPHRRPMQLIAERACALTDAEQAIVLVPADPGEPGNPEVDTLVVS 243
Query 274 ETVGSAVASIVGRTIPVAGAVLREVFVNGIPRRVDRVDLEGLDELADAG--PALLLPLRA 331
VG A ++G+ +PV G+ VF +G P D + DAG PA+++PLRA
Sbjct 244 AAVGLPAADVLGQRVPVRGSTSGAVFKSGEPLITDEFRYP-IQAFTDAGRRPAIVMPLRA 302
Query 332 RGTVAGVVVVLSQGGPGAFTDEQLEMMAAFADQAALAWQLATSQRRMRELDVLTDRDRIA 391
R V GV+ + F + L+++ FA AA+A LA ++ R+L VL +R+RIA
Sbjct 303 RDEVVGVIAIARGTEQPPFDESYLDLVRDFATHAAIALVLAAAREDARQLAVLAERERIA 362
Query 392 RDLHDHVIQRLFAIGLALQGAVPHERNPEVQQRLSDVVDDLQDVIQEIRTTIYDLHGASQ 451
DLHDHVIQRLFA G+ LQG + R+PEV RL+ +DDLQ +I+EIRTTI+ L +
Sbjct 363 HDLHDHVIQRLFAAGMDLQGTLARARSPEVADRLNRTLDDLQTIIEEIRTTIFALRSPAA 422
Query 452 GITRLRQRIDAAVAQFADS-GLRTSVQFVGPLSVVDSALADQAEAVVREAVSNAVRHAKA 510
R RI +A+ ++ L T+V+ GP++ V + LA+ AEAV EAVSNAVRH+ A
Sbjct 423 VAGDFRHRIQRVIAELTENRDLVTTVRMDGPMTAVGAELAEHAEAVTVEAVSNAVRHSGA 482
Query 511 STLTVRVKVDDDLCIEVTDNGRGLPDEFT-GSGLTNLRQRAEQAGGEFTLASVPGASGTV 569
S LTV++ V D ++V DNGRG+ T SGL N+ +RAEQ GG ++S PG GT
Sbjct 483 SRLTVQIGVADMFTLDVIDNGRGIASGNTRRSGLANMTRRAEQLGGSCEISSPPGG-GTR 541
Query 570 LRWSAPL 576
+ W+APL
Sbjct 542 VHWTAPL 548
>gi|118467162|ref|YP_883257.1| GAF family protein [Mycobacterium avium 104]
gi|118168449|gb|ABK69346.1| GAF family protein [Mycobacterium avium 104]
Length=551
Score = 388 bits (997), Expect = 1e-105, Method: Compositional matrix adjust.
Identities = 240/547 (44%), Positives = 340/547 (63%), Gaps = 8/547 (1%)
Query 36 DRVEQIVEGRDRLDGLVEAMLVVTAGLDLEATLRAIVHSATSLVDARYGAMEVHDRQHRV 95
+R +++ RD+ + L+ + + AGLDL+ATL I+ +A L A YGA+ V D +
Sbjct 4 NRFDELAAARDQTEKLLRVIAEIGAGLDLDATLHRIISAARELTSAPYGALAVRDWHANL 63
Query 96 LHFVYEGIDEETVRRIGHLPKGLGVIGLLIEDPKPLRLDDVSAHPASIGFPPYHPPMRTF 155
+ FV+EG+D ETVRRIGH P G G++ L + D LR+DD++AHPA+ GFP +HP MR F
Sbjct 64 ISFVHEGMDAETVRRIGHHPVGKGLLSLSLLDTPALRMDDLTAHPAAAGFPEHHPAMRAF 123
Query 156 LGVPVRVRDESFGTLYLTDKTNGQPFSDDDEVLVQALAAAAGIAVANARLYQQAKARQSW 215
L VP+ +R FG LYLT + FSD DE+ +ALA AA +A+ NA+++++ + W
Sbjct 124 LAVPITIRGAVFGNLYLTHVDEARVFSDADEMAARALAFAAAVAIDNAQVFERERMSVKW 183
Query 216 IEATRDIATELLSGTEPA-TVFRLVAAEALKLTAADAALVAVPVDEDMPA-ADVGELLVI 273
IEA+R+I T LLS TEP +L+A A LT A+ A+V VP D + P +V L+V
Sbjct 184 IEASREITTALLSRTEPHRRPMQLIAERACALTDAEQAIVLVPADPEQPGNPEVDTLVVS 243
Query 274 ETVGSAVASIVGRTIPVAGAVLREVFVNGIPRRVDRVDLEGLDELADAG--PALLLPLRA 331
VG A ++G+ +PV G+ VF +G P D + DAG PA+++PLRA
Sbjct 244 AAVGLPAADVLGQRVPVRGSTSGAVFKSGEPLITDEFRYP-IQAFTDAGRRPAIVMPLRA 302
Query 332 RGTVAGVVVVLSQGGPGAFTDEQLEMMAAFADQAALAWQLATSQRRMRELDVLTDRDRIA 391
R V GV+ + F + L+++ FA AA+A LA ++ R+L VL +R+RIA
Sbjct 303 RDEVVGVIAIARGTEQPPFDESYLDLVRDFATHAAIALVLAAAREDARQLAVLAERERIA 362
Query 392 RDLHDHVIQRLFAIGLALQGAVPHERNPEVQQRLSDVVDDLQDVIQEIRTTIYDLHGASQ 451
DLHDHVIQRLFA G+ LQG + R+PEV RL+ +DDLQ +I+EIRTTI+ L +
Sbjct 363 HDLHDHVIQRLFAAGMDLQGTLARARSPEVADRLNRTLDDLQTIIEEIRTTIFALRSPAA 422
Query 452 GITRLRQRIDAAVAQFADS-GLRTSVQFVGPLSVVDSALADQAEAVVREAVSNAVRHAKA 510
R RI +A+ ++ L T+V+ GP++ V + LA+ AEAV EAVSNAVRH+ A
Sbjct 423 VAGDFRHRIQRVIAELTENRDLVTTVRMDGPMTAVGAELAEHAEAVTAEAVSNAVRHSGA 482
Query 511 STLTVRVKVDDDLCIEVTDNGRGLPDEFT-GSGLTNLRQRAEQAGGEFTLASVPGASGTV 569
S LTV++ V D ++V DNGRG+ T SGL N+ +RAEQ GG ++S PG GT
Sbjct 483 SRLTVQIGVADMFTLDVIDNGRGIAAGNTRRSGLANMTRRAEQLGGSCEISSPPGG-GTR 541
Query 570 LRWSAPL 576
+ W+APL
Sbjct 542 VHWTAPL 548
>gi|340528954|gb|AEK44159.1| two-component system sensor kinase [Amycolatopsis mediterranei
S699]
Length=519
Score = 387 bits (993), Expect = 3e-105, Method: Compositional matrix adjust.
Identities = 251/536 (47%), Positives = 333/536 (63%), Gaps = 25/536 (4%)
Query 48 LDGLVEAMLVVTAGLDLEATLRAIVHSATSLVDARYGAMEVHDRQHRVLHFVYEGIDEET 107
+D L A+L +AGL+LE TL IV +A LV ARYGA+ + D R F G+D+ T
Sbjct 1 MDALPAAVLAFSAGLELETTLDRIVTAAAGLVGARYGALALLDEDGRTTAFAVTGVDDAT 60
Query 108 VRRIGHLPKGLGVIGLLIEDPKPLRLDDVSAHPASIGFPPYHPPMRTFLGVPVRVRDESF 167
R+G P G GV+G L+ P+RL AH + G PP HP M FLGVP+ VR E
Sbjct 61 RERLGPPPDGHGVLGTLVTGRAPVRL----AHLGNGGLPPEHPSMGAFLGVPLLVRGEIL 116
Query 168 GTLYLTDKTNGQPFSDDDEVLVQALAAAAGIAVANARLYQQAKARQSWIEATRDIATELL 227
G LYL+ + QPF+ DDE ALAAAAGIAV NARLY+++++RQ W+EAT +I+ ELL
Sbjct 117 GRLYLSRE---QPFTTDDERATVALAAAAGIAVDNARLYEESRSRQRWLEATGEISAELL 173
Query 228 SGTEPATVFRLVAAEALKLTAADAALVAVPVDEDMPAADVGELLVIETVGSAVASIVGRT 287
GT+ V L+A A +LT AD AL+A P + P G L+V G + GR
Sbjct 174 GGTDVREVLHLIATRAAELTGADDALIAWP---ESPG---GPLVVKVCAGPDADVLAGRR 227
Query 288 IPVAGAVLREVFVNGIPRRVDRVDLEGLDELA-DAGPALLLPLRARGTVAGVVVVLSQGG 346
IP+ G+ V + +PR V + + L D GPAL++ LR+ G+ +G V+L+ G
Sbjct 228 IPLDGSTAGAVLRDHVPRSVPSLAFDLAAGLGVDLGPALVVRLRS-GSRSGGAVLLAIRG 286
Query 347 PGA--FTDEQLEMMAAFADQAALAWQLATSQRRMRELDVLTDRDRIARDLHDHVIQRLFA 404
GA F + +L++++AFADQAALA + A SQ RELDV+ DRDRIARDLHDHVIQRLFA
Sbjct 287 RGAARFGEHELQLVSAFADQAALALRDAESQAARRELDVVVDRDRIARDLHDHVIQRLFA 346
Query 405 IGLALQGAVPHERNPEVQQRLSDVVDDLQDVIQEIRTTIYDLH---GASQGITRLRQRID 461
+GL ++G +P V RL +D LQDVI+EIR+ I+ LH GA +G LR R+
Sbjct 347 VGLGIEGTRRRSDSPAVTSRLIQHIDQLQDVIEEIRSAIFALHAQPGAGRG---LRARLQ 403
Query 462 AAVAQ-FADSGLRTSVQFVGPLSVVDSALADQAEAVVREAVSNAVRHAKASTLTVRVKVD 520
A+ ADS +RT+V+ G V + LA+ AEAVVREAV+N +RHA+A+ L V V +D
Sbjct 404 NAITDGCADSAIRTTVRLSGAFDRVPAGLAEHAEAVVREAVTNVLRHARAADLAVTVSLD 463
Query 521 DDLCIEVTDNGRGLPDEFTGSGLTNLRQRAEQAGGEFTLASVPGASGTVLRWSAPL 576
DDL +EV+D G G+P+ SGL NL QRA +AGG L P GT L W+ P+
Sbjct 464 DDLVVEVSDTGIGMPEAVARSGLRNLEQRAAEAGGSLRL-DRPAGGGTCLVWTVPV 518
>gi|337764230|emb|CCB72939.1| Two-component sensor [Streptomyces cattleya NRRL 8057]
Length=578
Score = 385 bits (989), Expect = 1e-104, Method: Compositional matrix adjust.
Identities = 257/587 (44%), Positives = 335/587 (58%), Gaps = 34/587 (5%)
Query 8 DENDGAAMRPLRHTLSQLRLHELLVEVQDRVEQIVEGRDRLDGLVEAMLVVTAGLDLEAT 67
D+ GA R R QLRL LL +Q VE++ RD++ L++++L + + LDLE
Sbjct 4 DDTLGAERR--RPAAPQLRLDVLLDALQQHVERVRGTRDQVQALLDSVLAIGSDLDLETV 61
Query 68 LRAIVHSATSLVDARYGAMEVHDRQHRVLHFVYEGIDEETVRRIGHLPKGLGVIGLLIED 127
LR IV SA LVDARYGA+ V + R+ F+ G+DE T+ IG P+G G++GLLI D
Sbjct 62 LRQIVQSAVDLVDARYGALGVLGEEGRIRRFITVGMDEGTIAAIGPYPRGEGILGLLIRD 121
Query 128 PKPLRLDDVSAHPASIGFPPYHPPMRTFLGVPVRVRDESFGTLYLTDKTNGQPFSDDDEV 187
P+PLRL D++ HP S+GFPP HPPMR FLGVPVRVRD+ FG LYLTDK + F DDE
Sbjct 122 PRPLRLPDLTRHPDSVGFPPGHPPMRGFLGVPVRVRDQVFGNLYLTDKRGTEGFDADDEA 181
Query 188 LVQALAAAAGIAVANARLYQQAKARQSWIEATRDIATELLSGTEPATVFRLVAAEALKLT 247
+++ LAAAA +A+ NARLY+ A+ RQ W+ A ++ LLSGTE + ++
Sbjct 182 VLRTLAAAASVAIDNARLYEDARRRQRWLAAGAELTRSLLSGTEVHQGLGTLTQTVREMA 241
Query 248 AADAALVAVPVDEDMPAADVGELLVIETVGSAVASIVGRTIPVAGAVLREVFVNGIPRRV 307
AD A +AVPV+ G+L+V G + G +P A + EV+ G P
Sbjct 242 GADLATLAVPVE------GTGDLVVEAAAGEQAERVRGLALPAA-TLAAEVYRTGEPVSS 294
Query 308 DRVDLE------GLDELADAGPALLLPLRARGTVAGVVVVLSQGGPGAFTDEQLEMMAAF 361
D V + G + GPA +PL + + GV+ + F D LEM+ F
Sbjct 295 DTVSADPRSRAGGSASRIELGPAFFVPLGSGDDIRGVLHIARVASGQPFGDAVLEMITGF 354
Query 362 ADQAALAWQLATSQRRMRELDVLTDRDRIARDLHDHVIQRLFAIGLALQGAVPHER---N 418
A QAALA + A +R L VL DRDRIARDLHD IQRLFA GL+LQ H R
Sbjct 355 AGQAALALKPAEHRRAAERLMVLDDRDRIARDLHDLAIQRLFASGLSLQAV--HGRLADR 412
Query 419 PEVQQRLSDVVDDLQDVIQEIRTTIYDLHGASQG-----ITRLRQRIDAAVAQFADSGLR 473
PE +R+ VVDDL D I+ IR+TIY LH G RL +DAA G
Sbjct 413 PEAAERVRRVVDDLDDTIKVIRSTIYSLHEHRHGDGTGPRARLLAEVDAAAGTL---GFT 469
Query 474 TSVQFVGPL-SVVDSALADQAEAVVREAVSNAVRHAKASTLTVRVKV-DDDLCIEVTDNG 531
S++ G L ++V ALA AV REA++NA RH+ A+T+ V V D L + V+D+G
Sbjct 470 PSLRMTGLLDTLVPDALAGHLTAVAREALANAARHSGATTVEVSAAVADGRLTLVVSDDG 529
Query 532 RGL-PDEFTGSGLTNLRQRAEQAGGEFTLASVPGAS-GTVLRWSAPL 576
RG+ P SGL NLR RAE GG F + PG S GT L WS PL
Sbjct 530 RGIDPSATRRSGLANLRSRAEDCGGTFRVG--PGRSRGTRLEWSVPL 574
>gi|336179935|ref|YP_004585310.1| putative signal transduction histidine kinase [Frankia symbiont
of Datisca glomerata]
gi|334860915|gb|AEH11389.1| putative signal transduction histidine kinase [Frankia symbiont
of Datisca glomerata]
Length=592
Score = 384 bits (987), Expect = 2e-104, Method: Compositional matrix adjust.
Identities = 237/573 (42%), Positives = 337/573 (59%), Gaps = 22/573 (3%)
Query 17 PLRH----TLSQLRLHELLVEVQDRVEQIVEGRDRLDGLVEAMLVVTAGLDLEATLRAIV 72
P+R +++L L ELL ++ DR + ++E + RL GL+ A V A L LE LR IV
Sbjct 30 PMREMAFPAVARLELDELLAQLVDRAQDVIETQSRLRGLLRATRTVIADLSLEVVLRRIV 89
Query 73 HSATSLVDARYGAMEVHDRQHRVLHFVYEGIDEETVRRIGHLPKGLGVIGLLIEDPKPLR 132
A LVDARYGA+ V R+ + F++ G++ V +IG LP+G GV+GLL P+PLR
Sbjct 90 EEACQLVDARYGALGVIAREGHLEQFIHVGMEPSLVEKIGQLPRGQGVLGLLTAQPQPLR 149
Query 133 LDDVSAHPASIGFPPYHPPMRTFLGVPVRVRDESFGTLYLTDKTNGQPFSDDDEVLVQAL 192
L+D++ +P ++GFP HPPM+TFLGVP+RVR E FG LYLT+K NG+ F+ +DE LV AL
Sbjct 150 LNDIATNPRAVGFPANHPPMQTFLGVPIRVRSEVFGNLYLTEKRNGRTFTAEDEELVLAL 209
Query 193 AAAAGIAVANARLYQQAKARQSWIEATRDIATELLS-GTEPATVFRLVAAEALKLTAADA 251
AA+AGIA+ NARL+ QA+ RQ W++A+ DI +L G P ++ + A +L AD
Sbjct 210 AASAGIAIDNARLFDQAQRRQRWLQASADITRHVLGDGERP---LNMIVSRARELAGADV 266
Query 252 ALVAVPVDEDMPAADVGELLVIETVGSAVASIVGRTIPVAGAVLREVFVNGIPRRVDRVD 311
A + + L V G + GR IP+ G++ + P V
Sbjct 267 AAIL------LSGGPSSHLTVEVADGDDAGVLQGRIIPMDGSLGGKAVRTCAPLLVSDAA 320
Query 312 LE--GLDELADA-GPALLLPLRARGTVAGVVVVLSQGGPGAFTDEQLEMMAAFADQAALA 368
E G D A GP +++PL G VV+ + G FTD L+M AAFA A A
Sbjct 321 AEASGNDPYAHGIGPLMIVPLAGSQVANGAVVLGRRHGATPFTDSDLDMAAAFAGHVATA 380
Query 369 WQLATSQRRMRELDVLTDRDRIARDLHDHVIQRLFAIGLALQGAVPHERNPEVQQRLSDV 428
++ ++ + VL DRDRIARDLHDHV+QRL+A+ L +QG E P +R++
Sbjct 381 LEITQARAARERIVVLEDRDRIARDLHDHVMQRLYAVALGMQGLAAAEERPGQARRMATY 440
Query 429 VDDLQDVIQEIRTTIYDLHG-ASQGITRLRQRIDAAVAQFADS-GLRTSVQFVGPL-SVV 485
V+DL I+EIR+T+++L G + + LR R+ + V +D+ G ++F GPL + V
Sbjct 441 VEDLDVTIREIRSTVFELRGRRTTAGSGLRARVASVVDAVSDAFGFAPYLRFEGPLDTAV 500
Query 486 DSALADQAEAVVREAVSNAVRHAKASTLTVRVKV-DDDLCIEVTDNGRGLPDEFTGSGLT 544
D+A + AVVRE +SNA RHA+AS++ V V+V L +V DNG G+ + SGL
Sbjct 501 DAAAGEHLLAVVREGLSNAARHARASSVEVIVRVTGGQLSADVIDNGVGIGNTERRSGLA 560
Query 545 NLRQRAEQAGGEFTLASVPGASGTVLRWSAPLS 577
N+R RAE GG F L++ P GT L WS PL+
Sbjct 561 NIRSRAEDLGGTFDLSAGP-EGGTHLCWSVPLA 592
>gi|296269629|ref|YP_003652261.1| GAF sensor signal transduction histidine kinase [Thermobispora
bispora DSM 43833]
gi|296092416|gb|ADG88368.1| GAF sensor signal transduction histidine kinase [Thermobispora
bispora DSM 43833]
Length=567
Score = 383 bits (983), Expect = 5e-104, Method: Compositional matrix adjust.
Identities = 241/568 (43%), Positives = 340/568 (60%), Gaps = 24/568 (4%)
Query 22 LSQLRLHELLVEVQDRVEQIVEGRDRLDGLVEAMLVVTAGLDLEATLRAIVHSATSLVDA 81
+ +RL ELL E+Q R+ ++ RDR+ L++A++ +++ LDLE LR +V +AT LVDA
Sbjct 10 IPHMRLDELLAELQVRLNAVLVTRDRVHALLQAVVSISSDLDLETVLRRLVETATDLVDA 69
Query 82 RYGAMEVHDRQHRVLHFVYEGIDEETVRRIGHLPKGLGVIGLLIEDPKPLRLDDVSAHPA 141
RYGAM V + ++ F+ G+ EE + +I H P+GLG++GLLI++P+ LRL D++ HP
Sbjct 70 RYGAMGVIGEDNTLIQFIPVGLSEEEIAKIDHWPRGLGLLGLLIKEPQTLRLADLTKHPQ 129
Query 142 SIGFPPYHPPMRTFLGVPVRVRDESFGTLYLTDKTNGQPFSDDDEVLVQALAAAAGIAVA 201
+ GFPP HP MR+FLGVP++VRDE FG LYL DK G F +DDE +V ALA AAG+A+
Sbjct 130 AYGFPPGHPHMRSFLGVPIKVRDEVFGNLYLADKRGGGSFDEDDEAIVVALATAAGVAIE 189
Query 202 NARLYQQAKARQSWIEATRDIATELLSGTEPATVFRLVAAEALKLTAADAALVAVPVDED 261
NARLY++ + R++W+EA+ +I T LLSG +P V L+A A ++T AD A + +P +D
Sbjct 190 NARLYEETRRRETWLEASSEITTRLLSGADPREVLLLIARRAREMTEADLAAILLPARDD 249
Query 262 MPAADVGELLVIETVGSAVASIVGRTIPVAGAVLREVFVNGIPRRVDR-VDLE---GLDE 317
G L V + G +PVAG++ FV P V D E GL
Sbjct 250 D-----GVLRVAAEDREQDRLVTGGEVPVAGSLAGHAFVTREPVTVSNPADTEFALGLTG 304
Query 318 LADAGPALLLPLRARGTVAGVVVVLSQGGPGAFTDEQLEMMAAFADQAALAWQLATSQRR 377
GP +PL A V GV+++ G F+ L M+ AFA AA+ +LA S++
Sbjct 305 RQPYGPVAAVPLGAADEVRGVLLLGKLSGRLPFSQADLRMLHAFAGHAAIGLELAESRKY 364
Query 378 MRELDVLTDRDRIARDLHDHVIQRLFAIGLALQGAVPH-ERNPEVQQRLSDVVDDLQDVI 436
L +L DRDRIA+DLHD VIQRLFA+ + L A E PE RL +D+L D I
Sbjct 365 AERLRLLEDRDRIAKDLHDVVIQRLFAVAMTLMSAARLVEERPEASSRLQSAIDELDDTI 424
Query 437 QEIRTTIYDLHGASQGITRLRQRIDAAVAQFADSGLRTSVQFVGPLSV-------VDSAL 489
++IRTTI+ L ++ LR +I V G R + F+ LS+ + + +
Sbjct 425 RQIRTTIFKLQMPAETEQSLRSKIVDLV-----EGARGHLGFMPGLSLEGRLDTEISAEV 479
Query 490 ADQAEAVVREAVSNAVRHAKASTLTVRVKVD-DDLCIEVTDNGRGLPDEFTGSGLTNLRQ 548
AD AV+REA+SN VRHAKA+ V V+ D + + V DNG G+P+ SGL NL +
Sbjct 480 ADHLLAVLREALSNVVRHAKATRADVSVRSDGKQVTLIVKDNGVGVPEGGRRSGLRNLAE 539
Query 549 RAEQAGGEFTLASVPGASGTVLRWSAPL 576
RAE+ GG F + P A GT+L W+APL
Sbjct 540 RAERLGGTFEITR-PEAGGTMLTWTAPL 566
Lambda K H
0.319 0.135 0.380
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 1304013394374
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
Posted date: Sep 5, 2011 4:36 AM
Number of letters in database: 5,219,829,388
Number of sequences in database: 15,229,318
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40