BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv3136 Length=380 Score E Sequences producing significant alignments: (Bits) Value gi|15842710|ref|NP_337747.1| PPE family protein [Mycobacterium t... 736 0.0 gi|306782177|ref|ZP_07420514.1| PPE family protein [Mycobacteriu... 734 0.0 gi|340628112|ref|YP_004746564.1| PPE family protein [Mycobacteri... 729 0.0 gi|167970194|ref|ZP_02552471.1| PPE family protein [Mycobacteriu... 709 0.0 gi|294993114|ref|ZP_06798805.1| PPE family protein [Mycobacteriu... 546 2e-153 gi|183980225|ref|YP_001848516.1| PPE family protein, PPE51_2 [My... 506 3e-141 gi|183981528|ref|YP_001849819.1| PPE family protein, PPE51 [Myco... 462 3e-128 gi|118617919|ref|YP_906251.1| PPE family protein [Mycobacterium ... 460 2e-127 gi|340628111|ref|YP_004746563.1| ppe family protein [Mycobacteri... 404 1e-110 gi|121639018|ref|YP_979242.1| PPE family protein [Mycobacterium ... 402 5e-110 gi|31794311|ref|NP_856804.1| PPE family protein [Mycobacterium b... 402 5e-110 gi|224991510|ref|YP_002646199.1| PPE family protein [Mycobacteri... 399 5e-109 gi|240168614|ref|ZP_04747273.1| PPE family protein, PPE51_2 [Myc... 395 6e-108 gi|240168615|ref|ZP_04747274.1| PPE family protein [Mycobacteriu... 391 1e-106 gi|183981529|ref|YP_001849820.1| PPE family protein, PPE51_1 [My... 355 6e-96 gi|118618187|ref|YP_906519.1| PPE family protein [Mycobacterium ... 350 3e-94 gi|118617918|ref|YP_906250.1| PPE family protein [Mycobacterium ... 346 3e-93 gi|289448814|ref|ZP_06438558.1| PPE family protein [Mycobacteriu... 342 8e-92 gi|183983449|ref|YP_001851740.1| PPE family protein, PPE51_3 [My... 331 1e-88 gi|289575846|ref|ZP_06456073.1| PPE family protein [Mycobacteriu... 316 4e-84 gi|298527010|ref|ZP_07014419.1| ppe family protein [Mycobacteriu... 311 2e-82 gi|289755661|ref|ZP_06515039.1| PPE family protein [Mycobacteriu... 309 6e-82 gi|289572184|ref|ZP_06452411.1| PPE family protein [Mycobacteriu... 307 2e-81 gi|31794708|ref|NP_857201.1| PPE family protein [Mycobacterium b... 305 8e-81 gi|308232493|ref|ZP_07416221.2| PPE family protein [Mycobacteriu... 305 1e-80 gi|339633530|ref|YP_004725172.1| PPE family protein [Mycobacteri... 304 2e-80 gi|289440961|ref|ZP_06430705.1| PPE family protein [Mycobacteriu... 303 4e-80 gi|240169296|ref|ZP_04747955.1| PPE family protein [Mycobacteriu... 296 3e-78 gi|183983432|ref|YP_001851723.1| PPE family protein, PPE61_1 [My... 278 1e-72 gi|183983433|ref|YP_001851724.1| PPE family protein, PPE61 [Myco... 276 3e-72 gi|118466535|ref|YP_883168.1| PPE family protein [Mycobacterium ... 267 2e-69 gi|41409283|ref|NP_962119.1| hypothetical protein MAP3185 [Mycob... 265 8e-69 gi|212596159|gb|ACJ35556.1| PPE33 [Mycobacterium avium subsp. av... 263 3e-68 gi|240173322|ref|ZP_04751980.1| PPE family protein [Mycobacteriu... 259 7e-67 gi|118618170|ref|YP_906502.1| PPE family protein [Mycobacterium ... 252 8e-65 gi|342861033|ref|ZP_08717682.1| PPE family protein [Mycobacteriu... 249 7e-64 gi|212596661|gb|ACJ35596.1| PPE32 [Mycobacterium intracellulare ... 237 3e-60 gi|118463069|ref|YP_883167.1| PPE family protein [Mycobacterium ... 230 3e-58 gi|342861034|ref|ZP_08717683.1| PPE family protein [Mycobacteriu... 228 1e-57 gi|183982688|ref|YP_001850979.1| PPE family protein, PPE31_1 [My... 224 3e-56 gi|240172861|ref|ZP_04751520.1| PPE family protein, PPE31 [Mycob... 219 4e-55 gi|240169037|ref|ZP_04747696.1| PPE family protein [Mycobacteriu... 219 5e-55 gi|212596672|gb|ACJ35597.1| PPE33 [Mycobacterium intracellulare ... 218 1e-54 gi|41409282|ref|NP_962118.1| hypothetical protein MAP3184 [Mycob... 218 1e-54 gi|254821012|ref|ZP_05226013.1| PPE family protein, PPE31 [Mycob... 211 1e-52 gi|342861296|ref|ZP_08717944.1| PPE family protein [Mycobacteriu... 210 3e-52 gi|183982689|ref|YP_001850980.1| PPE family protein [Mycobacteri... 209 4e-52 gi|296170357|ref|ZP_06851948.1| PPE family protein [Mycobacteriu... 207 3e-51 gi|240169314|ref|ZP_04747973.1| PPE family protein [Mycobacteriu... 204 2e-50 gi|240171463|ref|ZP_04750122.1| PPE family protein [Mycobacteriu... 204 3e-50 >gi|15842710|ref|NP_337747.1| PPE family protein [Mycobacterium tuberculosis CDC1551] gi|31794312|ref|NP_856805.1| PPE family protein [Mycobacterium bovis AF2122/97] gi|57117065|ref|YP_177935.1| PPE family protein [Mycobacterium tuberculosis H37Rv] 69 more sequence titles Length=380 Score = 736 bits (1901), Expect = 0.0, Method: Compositional matrix adjust. Identities = 380/380 (100%), Positives = 380/380 (100%), Gaps = 0/380 (0%) Query 1 MDFALLPPEVNSARMYTGPGAGSLLAAAGGWDSLAAELATTAEAYGSVLSGLAALHWRGP 60 MDFALLPPEVNSARMYTGPGAGSLLAAAGGWDSLAAELATTAEAYGSVLSGLAALHWRGP Sbjct 1 MDFALLPPEVNSARMYTGPGAGSLLAAAGGWDSLAAELATTAEAYGSVLSGLAALHWRGP 60 Query 61 AAESMAVTAAPYIGWLYTTAEKTQQTAIQARAAALAFEQAYAMTLPPPVVAANRIQLLAL 120 AAESMAVTAAPYIGWLYTTAEKTQQTAIQARAAALAFEQAYAMTLPPPVVAANRIQLLAL Sbjct 61 AAESMAVTAAPYIGWLYTTAEKTQQTAIQARAAALAFEQAYAMTLPPPVVAANRIQLLAL 120 Query 121 IATNFFGQNTAAIAATEAQYAEMWAQDAAAMYGYATASAAAALLTPFSPPRQTTNPAGLT 180 IATNFFGQNTAAIAATEAQYAEMWAQDAAAMYGYATASAAAALLTPFSPPRQTTNPAGLT Sbjct 121 IATNFFGQNTAAIAATEAQYAEMWAQDAAAMYGYATASAAAALLTPFSPPRQTTNPAGLT 180 Query 181 AQAAAVSQATDPLSLLIETVTQALQALTIPSFIPEDFTFLDAIFAGYATVGVTQDVESFV 240 AQAAAVSQATDPLSLLIETVTQALQALTIPSFIPEDFTFLDAIFAGYATVGVTQDVESFV Sbjct 181 AQAAAVSQATDPLSLLIETVTQALQALTIPSFIPEDFTFLDAIFAGYATVGVTQDVESFV 240 Query 241 AGTIGAESNLGLLNVGDENPAEVTPGDFGIGELVSATSPGGGVSASGAGGAASVGNTVLA 300 AGTIGAESNLGLLNVGDENPAEVTPGDFGIGELVSATSPGGGVSASGAGGAASVGNTVLA Sbjct 241 AGTIGAESNLGLLNVGDENPAEVTPGDFGIGELVSATSPGGGVSASGAGGAASVGNTVLA 300 Query 301 SVGRANSIGQLSVPPSWAAPSTRPVSALSPAGLTTLPGTDVAEHGMPGVPGVPVAAGRAS 360 SVGRANSIGQLSVPPSWAAPSTRPVSALSPAGLTTLPGTDVAEHGMPGVPGVPVAAGRAS Sbjct 301 SVGRANSIGQLSVPPSWAAPSTRPVSALSPAGLTTLPGTDVAEHGMPGVPGVPVAAGRAS 360 Query 361 GVLPRYGVRLTVMAHPPAAG 380 GVLPRYGVRLTVMAHPPAAG Sbjct 361 GVLPRYGVRLTVMAHPPAAG 380 >gi|306782177|ref|ZP_07420514.1| PPE family protein [Mycobacterium tuberculosis SUMu002] gi|306790362|ref|ZP_07428684.1| PPE family protein [Mycobacterium tuberculosis SUMu004] gi|306794889|ref|ZP_07433191.1| PPE family protein [Mycobacterium tuberculosis SUMu005] gi|308325139|gb|EFP13990.1| PPE family protein [Mycobacterium tuberculosis SUMu002] gi|308333218|gb|EFP22069.1| PPE family protein [Mycobacterium tuberculosis SUMu004] gi|308336675|gb|EFP25526.1| PPE family protein [Mycobacterium tuberculosis SUMu005] Length=380 Score = 734 bits (1895), Expect = 0.0, Method: Compositional matrix adjust. Identities = 379/380 (99%), Positives = 379/380 (99%), Gaps = 0/380 (0%) Query 1 MDFALLPPEVNSARMYTGPGAGSLLAAAGGWDSLAAELATTAEAYGSVLSGLAALHWRGP 60 MDFALLPPEVNSARMYTGPGAGSLLAAAGGWDSLAAELATTAEAYGSVLSGLAALHWRGP Sbjct 1 MDFALLPPEVNSARMYTGPGAGSLLAAAGGWDSLAAELATTAEAYGSVLSGLAALHWRGP 60 Query 61 AAESMAVTAAPYIGWLYTTAEKTQQTAIQARAAALAFEQAYAMTLPPPVVAANRIQLLAL 120 AAESMAVTAAPYIGWLYTTAEKTQQTAIQARAAALAFEQAYAMTLPPPVVAANRIQLLAL Sbjct 61 AAESMAVTAAPYIGWLYTTAEKTQQTAIQARAAALAFEQAYAMTLPPPVVAANRIQLLAL 120 Query 121 IATNFFGQNTAAIAATEAQYAEMWAQDAAAMYGYATASAAAALLTPFSPPRQTTNPAGLT 180 IATNFFGQNTAAIAATEAQYAEMWAQDAAAMYGYATASAAAALLTPFSPPRQTTNPAGLT Sbjct 121 IATNFFGQNTAAIAATEAQYAEMWAQDAAAMYGYATASAAAALLTPFSPPRQTTNPAGLT 180 Query 181 AQAAAVSQATDPLSLLIETVTQALQALTIPSFIPEDFTFLDAIFAGYATVGVTQDVESFV 240 AQAAAVSQATDPLSLLIET TQALQALTIPSFIPEDFTFLDAIFAGYATVGVTQDVESFV Sbjct 181 AQAAAVSQATDPLSLLIETATQALQALTIPSFIPEDFTFLDAIFAGYATVGVTQDVESFV 240 Query 241 AGTIGAESNLGLLNVGDENPAEVTPGDFGIGELVSATSPGGGVSASGAGGAASVGNTVLA 300 AGTIGAESNLGLLNVGDENPAEVTPGDFGIGELVSATSPGGGVSASGAGGAASVGNTVLA Sbjct 241 AGTIGAESNLGLLNVGDENPAEVTPGDFGIGELVSATSPGGGVSASGAGGAASVGNTVLA 300 Query 301 SVGRANSIGQLSVPPSWAAPSTRPVSALSPAGLTTLPGTDVAEHGMPGVPGVPVAAGRAS 360 SVGRANSIGQLSVPPSWAAPSTRPVSALSPAGLTTLPGTDVAEHGMPGVPGVPVAAGRAS Sbjct 301 SVGRANSIGQLSVPPSWAAPSTRPVSALSPAGLTTLPGTDVAEHGMPGVPGVPVAAGRAS 360 Query 361 GVLPRYGVRLTVMAHPPAAG 380 GVLPRYGVRLTVMAHPPAAG Sbjct 361 GVLPRYGVRLTVMAHPPAAG 380 >gi|340628112|ref|YP_004746564.1| PPE family protein [Mycobacterium canettii CIPT 140010059] gi|340006302|emb|CCC45481.1| PPE family protein [Mycobacterium canettii CIPT 140010059] Length=380 Score = 729 bits (1881), Expect = 0.0, Method: Compositional matrix adjust. Identities = 377/380 (99%), Positives = 378/380 (99%), Gaps = 0/380 (0%) Query 1 MDFALLPPEVNSARMYTGPGAGSLLAAAGGWDSLAAELATTAEAYGSVLSGLAALHWRGP 60 MDFALLPPEVNSARMYTGPGAGSL AAAGGWDSLAAELATTAEAYGSVLSGLAALHWRGP Sbjct 1 MDFALLPPEVNSARMYTGPGAGSLWAAAGGWDSLAAELATTAEAYGSVLSGLAALHWRGP 60 Query 61 AAESMAVTAAPYIGWLYTTAEKTQQTAIQARAAALAFEQAYAMTLPPPVVAANRIQLLAL 120 AAESMAVTAA YIGWLYTTAEKTQQTAIQARAAALAFEQAYAMTLPPP+VAANRIQLLAL Sbjct 61 AAESMAVTAAAYIGWLYTTAEKTQQTAIQARAAALAFEQAYAMTLPPPLVAANRIQLLAL 120 Query 121 IATNFFGQNTAAIAATEAQYAEMWAQDAAAMYGYATASAAAALLTPFSPPRQTTNPAGLT 180 IATNFFGQNTAAIAATEAQYAEMWAQDAAAMYGYATASAAAALLTPFSPPRQTTNPAGLT Sbjct 121 IATNFFGQNTAAIAATEAQYAEMWAQDAAAMYGYATASAAAALLTPFSPPRQTTNPAGLT 180 Query 181 AQAAAVSQATDPLSLLIETVTQALQALTIPSFIPEDFTFLDAIFAGYATVGVTQDVESFV 240 AQAAAVSQATDPLSLLIETVTQALQALTIPSFIPEDFTFLDAIFAGYATVGVTQDVESFV Sbjct 181 AQAAAVSQATDPLSLLIETVTQALQALTIPSFIPEDFTFLDAIFAGYATVGVTQDVESFV 240 Query 241 AGTIGAESNLGLLNVGDENPAEVTPGDFGIGELVSATSPGGGVSASGAGGAASVGNTVLA 300 AGTIGAESNLGLLNVGDENPAEVTPGDFGIGELVSATSPGGGVSASGAGGAASVGNTVLA Sbjct 241 AGTIGAESNLGLLNVGDENPAEVTPGDFGIGELVSATSPGGGVSASGAGGAASVGNTVLA 300 Query 301 SVGRANSIGQLSVPPSWAAPSTRPVSALSPAGLTTLPGTDVAEHGMPGVPGVPVAAGRAS 360 SVGRANSIGQLSVPPSWAAPSTRPVSALSPAGLTTLPGTDVAEHGMPGVPGVPVAAGRAS Sbjct 301 SVGRANSIGQLSVPPSWAAPSTRPVSALSPAGLTTLPGTDVAEHGMPGVPGVPVAAGRAS 360 Query 361 GVLPRYGVRLTVMAHPPAAG 380 GVLPRYGVRLTVMAHPPAAG Sbjct 361 GVLPRYGVRLTVMAHPPAAG 380 >gi|167970194|ref|ZP_02552471.1| PPE family protein [Mycobacterium tuberculosis H37Ra] Length=480 Score = 709 bits (1830), Expect = 0.0, Method: Compositional matrix adjust. Identities = 366/366 (100%), Positives = 366/366 (100%), Gaps = 0/366 (0%) Query 1 MDFALLPPEVNSARMYTGPGAGSLLAAAGGWDSLAAELATTAEAYGSVLSGLAALHWRGP 60 MDFALLPPEVNSARMYTGPGAGSLLAAAGGWDSLAAELATTAEAYGSVLSGLAALHWRGP Sbjct 1 MDFALLPPEVNSARMYTGPGAGSLLAAAGGWDSLAAELATTAEAYGSVLSGLAALHWRGP 60 Query 61 AAESMAVTAAPYIGWLYTTAEKTQQTAIQARAAALAFEQAYAMTLPPPVVAANRIQLLAL 120 AAESMAVTAAPYIGWLYTTAEKTQQTAIQARAAALAFEQAYAMTLPPPVVAANRIQLLAL Sbjct 61 AAESMAVTAAPYIGWLYTTAEKTQQTAIQARAAALAFEQAYAMTLPPPVVAANRIQLLAL 120 Query 121 IATNFFGQNTAAIAATEAQYAEMWAQDAAAMYGYATASAAAALLTPFSPPRQTTNPAGLT 180 IATNFFGQNTAAIAATEAQYAEMWAQDAAAMYGYATASAAAALLTPFSPPRQTTNPAGLT Sbjct 121 IATNFFGQNTAAIAATEAQYAEMWAQDAAAMYGYATASAAAALLTPFSPPRQTTNPAGLT 180 Query 181 AQAAAVSQATDPLSLLIETVTQALQALTIPSFIPEDFTFLDAIFAGYATVGVTQDVESFV 240 AQAAAVSQATDPLSLLIETVTQALQALTIPSFIPEDFTFLDAIFAGYATVGVTQDVESFV Sbjct 181 AQAAAVSQATDPLSLLIETVTQALQALTIPSFIPEDFTFLDAIFAGYATVGVTQDVESFV 240 Query 241 AGTIGAESNLGLLNVGDENPAEVTPGDFGIGELVSATSPGGGVSASGAGGAASVGNTVLA 300 AGTIGAESNLGLLNVGDENPAEVTPGDFGIGELVSATSPGGGVSASGAGGAASVGNTVLA Sbjct 241 AGTIGAESNLGLLNVGDENPAEVTPGDFGIGELVSATSPGGGVSASGAGGAASVGNTVLA 300 Query 301 SVGRANSIGQLSVPPSWAAPSTRPVSALSPAGLTTLPGTDVAEHGMPGVPGVPVAAGRAS 360 SVGRANSIGQLSVPPSWAAPSTRPVSALSPAGLTTLPGTDVAEHGMPGVPGVPVAAGRAS Sbjct 301 SVGRANSIGQLSVPPSWAAPSTRPVSALSPAGLTTLPGTDVAEHGMPGVPGVPVAAGRAS 360 Query 361 GVLPRY 366 GVLPRY Sbjct 361 GVLPRY 366 >gi|294993114|ref|ZP_06798805.1| PPE family protein [Mycobacterium tuberculosis 210] Length=282 Score = 546 bits (1407), Expect = 2e-153, Method: Compositional matrix adjust. Identities = 282/282 (100%), Positives = 282/282 (100%), Gaps = 0/282 (0%) Query 99 QAYAMTLPPPVVAANRIQLLALIATNFFGQNTAAIAATEAQYAEMWAQDAAAMYGYATAS 158 QAYAMTLPPPVVAANRIQLLALIATNFFGQNTAAIAATEAQYAEMWAQDAAAMYGYATAS Sbjct 1 QAYAMTLPPPVVAANRIQLLALIATNFFGQNTAAIAATEAQYAEMWAQDAAAMYGYATAS 60 Query 159 AAAALLTPFSPPRQTTNPAGLTAQAAAVSQATDPLSLLIETVTQALQALTIPSFIPEDFT 218 AAAALLTPFSPPRQTTNPAGLTAQAAAVSQATDPLSLLIETVTQALQALTIPSFIPEDFT Sbjct 61 AAAALLTPFSPPRQTTNPAGLTAQAAAVSQATDPLSLLIETVTQALQALTIPSFIPEDFT 120 Query 219 FLDAIFAGYATVGVTQDVESFVAGTIGAESNLGLLNVGDENPAEVTPGDFGIGELVSATS 278 FLDAIFAGYATVGVTQDVESFVAGTIGAESNLGLLNVGDENPAEVTPGDFGIGELVSATS Sbjct 121 FLDAIFAGYATVGVTQDVESFVAGTIGAESNLGLLNVGDENPAEVTPGDFGIGELVSATS 180 Query 279 PGGGVSASGAGGAASVGNTVLASVGRANSIGQLSVPPSWAAPSTRPVSALSPAGLTTLPG 338 PGGGVSASGAGGAASVGNTVLASVGRANSIGQLSVPPSWAAPSTRPVSALSPAGLTTLPG Sbjct 181 PGGGVSASGAGGAASVGNTVLASVGRANSIGQLSVPPSWAAPSTRPVSALSPAGLTTLPG 240 Query 339 TDVAEHGMPGVPGVPVAAGRASGVLPRYGVRLTVMAHPPAAG 380 TDVAEHGMPGVPGVPVAAGRASGVLPRYGVRLTVMAHPPAAG Sbjct 241 TDVAEHGMPGVPGVPVAAGRASGVLPRYGVRLTVMAHPPAAG 282 >gi|183980225|ref|YP_001848516.1| PPE family protein, PPE51_2 [Mycobacterium marinum M] gi|183173551|gb|ACC38661.1| PPE family protein, PPE51_2 [Mycobacterium marinum M] Length=381 Score = 506 bits (1302), Expect = 3e-141, Method: Compositional matrix adjust. Identities = 268/390 (69%), Positives = 311/390 (80%), Gaps = 19/390 (4%) Query 1 MDFALLPPEVNSARMYTGPGAGSLLAAAGGWDSLAAELATTAEAYGSVLSGLAALHWRGP 60 MDFA+LPPEVNS MYTGPGAGSLLAAA WD LA EL TTA+ Y SVLSGL +++W GP Sbjct 1 MDFAMLPPEVNSGLMYTGPGAGSLLAAANSWDELAIELGTTAQTYESVLSGLTSMYWAGP 60 Query 61 AAESMAVTAAPYIGWLYTTAEKTQQTAIQARAAALAFEQAYAMTLPPPVVAANRIQLLAL 120 A+ESMA AAPY+ WL++TAE+TQQTA Q RAAA+AFEQAYAMT+PPPV+ ANR+QL++L Sbjct 61 ASESMAAKAAPYVWWLHSTAEQTQQTATQCRAAAMAFEQAYAMTVPPPVILANRMQLMSL 120 Query 121 IATNFFGQNTAAIAATEAQYAEMWAQDAAAMYGYATASAAAALLTPFSPPRQTTNPAGLT 180 +ATNFFGQNTAAIAA EAQYAEMW QDAAAMYGYAT++A AA L PFS P+QTTNPAGL+ Sbjct 121 VATNFFGQNTAAIAALEAQYAEMWEQDAAAMYGYATSAAMAAQLVPFSSPQQTTNPAGLS 180 Query 181 AQAAAVSQ------ATDPLSLLIETVTQALQAL--TIPSFIPEDFTFLDAIFAGYATVGV 232 AQ+AAV+Q A +PLS LI V + L AL P+ +P+DF+ LD IFAGYATVGV Sbjct 181 AQSAAVNQADATAAAANPLSDLIALVQKGLAALAGAFPNLLPDDFSILDGIFAGYATVGV 240 Query 233 TQDVESFVAGTIGAESNLGLLNVGDENPAEVTPGDFGIGE-LVSATSPGGGVSASGAGGA 291 +QD ES +AG IGAESNLG+L ENPAE+ PGD GIG L SA S GG VS GA Sbjct 241 SQDCESIIAGIIGAESNLGMLGAASENPAELAPGDIGIGSVLSSAPSVGGAVSGPGA--- 297 Query 292 ASVGNTVLASVGRANSIGQLSVPPSWAAPSTRPVSALSPAGLTTLPGTDVAEHGMPGVPG 351 VL SVGRA SIGQLSVP SWAAP+TR V+ALS AGLTT+PGT+ A HG+PG+PG Sbjct 298 ------VLVSVGRAGSIGQLSVPASWAAPATRQVAALSSAGLTTIPGTEEAAHGIPGMPG 351 Query 352 VPV-AAGRASGVLPRYGVRLTVMAHPPAAG 380 +PV ++ RAS V+PRYGVRLTVMAHPPAAG Sbjct 352 MPVGSSSRASSVVPRYGVRLTVMAHPPAAG 381 >gi|183981528|ref|YP_001849819.1| PPE family protein, PPE51 [Mycobacterium marinum M] gi|183174854|gb|ACC39964.1| PPE family protein, PPE51 [Mycobacterium marinum M] Length=382 Score = 462 bits (1190), Expect = 3e-128, Method: Compositional matrix adjust. Identities = 273/389 (71%), Positives = 314/389 (81%), Gaps = 16/389 (4%) Query 1 MDFALLPPEVNSARMYTGPGAGSLLAAAGGWDSLAAELATTAEAYGSVLSGLAALHWRGP 60 MDF+LLPPEVNSARMYTGPG+GSLLAAA WD+LAAEL TTAE GS+L+GL L WRGP Sbjct 1 MDFSLLPPEVNSARMYTGPGSGSLLAAAASWDALAAELGTTAETCGSILTGLTDLSWRGP 60 Query 61 AAESMAVTAAPYIGWLYTTAEKTQQTAIQARAAALAFEQAYAMTLPPPVVAANRIQLLAL 120 A+ESMA +AAPY+GWLY TAE+TQQ AIQAR AALAFEQAYAMT+PPP+VAANR QLL L Sbjct 61 ASESMAASAAPYVGWLYRTAEQTQQAAIQARTAALAFEQAYAMTVPPPLVAANRAQLLVL 120 Query 121 IATNFFGQNTAAIAATEAQYAEMWAQDAAAMYGYATASAAAALLTPFSPPRQTTNPAGLT 180 IATNFFGQNT+AIAA EAQYAEMWAQDAAAMYGYAT SAAA +LTPFS P Q T+PAGL Sbjct 121 IATNFFGQNTSAIAANEAQYAEMWAQDAAAMYGYATTSAAAGMLTPFSSPNQATSPAGLA 180 Query 181 AQA------AAVSQATDPLSLLIETVTQALQALT-IPSFIPEDFTFLDAIFAGYATVGVT 233 AQ+ A + ATDP++ L+ ++TQ+L A+ IPS +P+DFT LD +F+ YATVGVT Sbjct 181 AQSTAVTQANATAAATDPITQLVSSLTQSLGAIQAIPSILPDDFTILDGVFSAYATVGVT 240 Query 234 QDVESFVAGTIGAESNLGLLNVGDENPAEVTPGDFGIGELVSATSPGGGVSASGAGGAAS 293 QD+ESF AG IGAE+NLGL+ ENPAEVTP DFG+G L+S+T+P S G Sbjct 241 QDIESFCAGVIGAENNLGLIG-SSENPAEVTPSDFGLGSLISSTAPASAASGGG------ 293 Query 294 VGNTVLASVGRANSIGQLSVPPSWAAPSTRPVSALSPAGLTTLPGT-DVAEHGMPGVPG- 351 +G+ V ASVGR+ SIGQLSVPPSW+APS R VSALSP+GLTT+PGT + A G PG PG Sbjct 294 LGSAVAASVGRSGSIGQLSVPPSWSAPSARMVSALSPSGLTTIPGTEEAAAAGSPGFPGM 353 Query 352 VPVAAGRASGVLPRYGVRLTVMAHPPAAG 380 V A RASGVLPRYGVRLTVMAHPPAAG Sbjct 354 VAPPATRASGVLPRYGVRLTVMAHPPAAG 382 >gi|118617919|ref|YP_906251.1| PPE family protein [Mycobacterium ulcerans Agy99] gi|118570029|gb|ABL04780.1| PPE family protein [Mycobacterium ulcerans Agy99] Length=382 Score = 460 bits (1184), Expect = 2e-127, Method: Compositional matrix adjust. Identities = 272/389 (70%), Positives = 313/389 (81%), Gaps = 16/389 (4%) Query 1 MDFALLPPEVNSARMYTGPGAGSLLAAAGGWDSLAAELATTAEAYGSVLSGLAALHWRGP 60 MDF+LLPPEVNSARMYTGPG+GSLLAAA WD+LAAEL TTAE GS+L+GL L WRGP Sbjct 1 MDFSLLPPEVNSARMYTGPGSGSLLAAAASWDALAAELGTTAETCGSILTGLTDLSWRGP 60 Query 61 AAESMAVTAAPYIGWLYTTAEKTQQTAIQARAAALAFEQAYAMTLPPPVVAANRIQLLAL 120 A+ESMA +AAP +GWLY TAE+TQQ AIQAR AALAFEQAYAMT+PPP+VAANR QLL L Sbjct 61 ASESMAASAAPCVGWLYRTAEQTQQAAIQARTAALAFEQAYAMTVPPPLVAANRAQLLVL 120 Query 121 IATNFFGQNTAAIAATEAQYAEMWAQDAAAMYGYATASAAAALLTPFSPPRQTTNPAGLT 180 IATNFFGQNT+AIAA EAQYAEMWAQDAAAMYGYAT SAAA +LTPFS P Q T+PAGL Sbjct 121 IATNFFGQNTSAIAANEAQYAEMWAQDAAAMYGYATTSAAAGMLTPFSSPNQATSPAGLA 180 Query 181 AQA------AAVSQATDPLSLLIETVTQALQALT-IPSFIPEDFTFLDAIFAGYATVGVT 233 AQ+ A + ATDP++ L+ ++TQ+L A+ IPS +P+DFT LD +F+ YATVGVT Sbjct 181 AQSTAVTQANATAAATDPITQLVSSLTQSLGAIQAIPSILPDDFTILDGVFSAYATVGVT 240 Query 234 QDVESFVAGTIGAESNLGLLNVGDENPAEVTPGDFGIGELVSATSPGGGVSASGAGGAAS 293 QD+ESF AG IGAE+NLGL+ ENPAEVTP DFG+G L+S+T+P S G Sbjct 241 QDIESFCAGVIGAENNLGLIG-SSENPAEVTPSDFGLGSLISSTAPASAASGGG------ 293 Query 294 VGNTVLASVGRANSIGQLSVPPSWAAPSTRPVSALSPAGLTTLPGT-DVAEHGMPGVPG- 351 +G+ V ASVGR+ SIGQLSVPPSW+APS R VSALSP+GLTT+PGT + A G PG PG Sbjct 294 LGSAVAASVGRSGSIGQLSVPPSWSAPSARMVSALSPSGLTTIPGTEEAAAAGSPGFPGM 353 Query 352 VPVAAGRASGVLPRYGVRLTVMAHPPAAG 380 V A RASGVLPRYGVRLTVMAHPPAAG Sbjct 354 VAPPATRASGVLPRYGVRLTVMAHPPAAG 382 >gi|340628111|ref|YP_004746563.1| ppe family protein [Mycobacterium canettii CIPT 140010059] gi|340006301|emb|CCC45480.1| ppe family protein [Mycobacterium canettii CIPT 140010059] Length=381 Score = 404 bits (1039), Expect = 1e-110, Method: Compositional matrix adjust. Identities = 252/390 (65%), Positives = 293/390 (76%), Gaps = 19/390 (4%) Query 1 MDFALLPPEVNSARMYTGPGAGSLLAAAGGWDSLAAELATTAEAYGSVLSGLAALHWRGP 60 MD+A LPPE+NSARMY+GPG S+L AA WD+LAAELA+ AE YGSV++ L +HW GP Sbjct 1 MDYAFLPPEINSARMYSGPGPNSMLVAAASWDALAAELASAAENYGSVIARLTGMHWWGP 60 Query 61 AAESMAVTAAPYIGWLYTTAEKTQQTAIQARAAALAFEQAYAMTLPPPVVAANRIQLLAL 120 A+ SM +APY+ WL TA +T+QTA QARAAA AFEQA+AMT+PP +V ANR +L AL Sbjct 61 ASTSMLAMSAPYVEWLERTAAQTKQTATQARAAAAAFEQAHAMTVPPALVTANRAELKAL 120 Query 121 IATNFFGQNTAAIAATEAQYAEMWAQDAAAMYGYATASAAAALLTPFSPPRQTTNPAGLT 180 IA+N GQNTAAIAA EAQYAEMWAQDAAAMYGYAT SAAA LTPFS P+QTTNPAGL Sbjct 121 IASNLLGQNTAAIAAIEAQYAEMWAQDAAAMYGYATTSAAARQLTPFSSPQQTTNPAGLA 180 Query 181 AQAAAVSQATDP--------LSLLIETVTQALQALT-IPSFIPEDFTFLDAIFAGYATVG 231 AQ AAV+QA LS L ++QA++A T P+ +P+DFT LD IFA YATVG Sbjct 181 AQNAAVTQAATNSAGNTPTALSQLSSFLSQAVEAPTGWPNILPDDFTILDGIFAAYATVG 240 Query 232 VTQDVESFVAGTIGAESNLGLLNVGDENPAEVTPGDFGIGELVSATSPGGGVSASGAGGA 291 VTQD+ES AG IGAE+NLGLL ENPAE+ PG FGI +S++ G A Sbjct 241 VTQDIESICAGIIGAENNLGLLGAASENPAELAPGAFGI---------DAALSSAEKGAA 291 Query 292 ASVGNTVLASVGRANSIGQLSVPPSWAAPSTRPVSALSPAGLTTLPGTDVAEHGMPGVPG 351 AS+ + VLAS GRA SIG +SVPPSWA PS+ PVSALS AGLTTL GTDVAEHG PG+PG Sbjct 292 ASMHDAVLASAGRAGSIGPMSVPPSWATPSSTPVSALSGAGLTTLDGTDVAEHGTPGLPG 351 Query 352 VPVAAG-RASGVLPRYGVRLTVMAHPPAAG 380 VP RASGV+PRYGVRLTVM+ PPAAG Sbjct 352 VPAGTDKRASGVIPRYGVRLTVMSRPPAAG 381 >gi|121639018|ref|YP_979242.1| PPE family protein [Mycobacterium bovis BCG str. Pasteur 1173P2] gi|121494666|emb|CAL73147.1| PPE family protein [Mycobacterium bovis BCG str. Pasteur 1173P2] Length=381 Score = 402 bits (1033), Expect = 5e-110, Method: Compositional matrix adjust. Identities = 251/390 (65%), Positives = 292/390 (75%), Gaps = 19/390 (4%) Query 1 MDFALLPPEVNSARMYTGPGAGSLLAAAGGWDSLAAELATTAEAYGSVLSGLAALHWRGP 60 MD+A LPPE+NSARMY+GPG S+L AA WD+LAAELA+ AE YGSV++ L +HW GP Sbjct 1 MDYAFLPPEINSARMYSGPGPNSMLVAAASWDALAAELASAAENYGSVIARLTGMHWWGP 60 Query 61 AAESMAVTAAPYIGWLYTTAEKTQQTAIQARAAALAFEQAYAMTLPPPVVAANRIQLLAL 120 A+ SM +APY+ WL TA +T+QTA QARAAA AFEQA+AMT+PP +V ANR +L AL Sbjct 61 ASTSMLAMSAPYVEWLERTAAQTKQTATQARAAAAAFEQAHAMTVPPALVTANRAELKAL 120 Query 121 IATNFFGQNTAAIAATEAQYAEMWAQDAAAMYGYATASAAAALLTPFSPPRQTTNPAGLT 180 IA+N GQNTAAIAA EAQYAEMWAQDAAAMYGYAT SAAA LTPFS P+QTTNPAGL Sbjct 121 IASNLLGQNTAAIAAIEAQYAEMWAQDAAAMYGYATTSAAARQLTPFSSPQQTTNPAGLA 180 Query 181 AQAAAVSQATDP--------LSLLIETVTQALQALT-IPSFIPEDFTFLDAIFAGYATVG 231 AQ AAV+QA LS L ++QA++A T P+ +P+DFT LD I A YATVG Sbjct 181 AQNAAVTQAATNSAGNTPTALSQLSSFLSQAVKAPTGWPNILPDDFTILDGILAAYATVG 240 Query 232 VTQDVESFVAGTIGAESNLGLLNVGDENPAEVTPGDFGIGELVSATSPGGGVSASGAGGA 291 VTQD+ES AG IGAE+NLGLL ENPAE+ PG FGI +S++ G A Sbjct 241 VTQDIESICAGIIGAENNLGLLGAASENPAELAPGAFGI---------DAALSSAEKGAA 291 Query 292 ASVGNTVLASVGRANSIGQLSVPPSWAAPSTRPVSALSPAGLTTLPGTDVAEHGMPGVPG 351 AS+ + VLAS GRA SIG +SVPPSWA PS+ PVSALS AGLTTL GTDVAEHG PG+PG Sbjct 292 ASMHDAVLASAGRAGSIGPMSVPPSWATPSSTPVSALSGAGLTTLDGTDVAEHGTPGLPG 351 Query 352 VPVAAG-RASGVLPRYGVRLTVMAHPPAAG 380 VP RASGV+PRYGVRLTVM+ PPAAG Sbjct 352 VPAGTDKRASGVIPRYGVRLTVMSRPPAAG 381 >gi|31794311|ref|NP_856804.1| PPE family protein [Mycobacterium bovis AF2122/97] gi|31619907|emb|CAD95251.1| PPE FAMILY PROTEIN [Mycobacterium bovis AF2122/97] gi|341603057|emb|CCC65735.1| PPE family protein [Mycobacterium bovis BCG str. Moreau RDJ] Length=381 Score = 402 bits (1033), Expect = 5e-110, Method: Compositional matrix adjust. Identities = 251/390 (65%), Positives = 292/390 (75%), Gaps = 19/390 (4%) Query 1 MDFALLPPEVNSARMYTGPGAGSLLAAAGGWDSLAAELATTAEAYGSVLSGLAALHWRGP 60 MD+A LPPE+NSARMY+GPG S+L AA WD+LAAELA+ AE YGSV++ L +HW GP Sbjct 1 MDYAFLPPEINSARMYSGPGPNSMLVAAASWDALAAELASAAENYGSVIARLTGMHWWGP 60 Query 61 AAESMAVTAAPYIGWLYTTAEKTQQTAIQARAAALAFEQAYAMTLPPPVVAANRIQLLAL 120 A+ SM +APY+ WL TA +T+QTA QARAAA AFEQA+AMT+PP +V ANR +L AL Sbjct 61 ASTSMLAMSAPYVEWLERTAAQTKQTATQARAAAAAFEQAHAMTVPPALVTANRAELKAL 120 Query 121 IATNFFGQNTAAIAATEAQYAEMWAQDAAAMYGYATASAAAALLTPFSPPRQTTNPAGLT 180 IA+N GQNTAAIAA EAQYAEMWAQDAAAMYGYAT SAAA LTPFS P+QTTNPAGL Sbjct 121 IASNLLGQNTAAIAAIEAQYAEMWAQDAAAMYGYATTSAAARQLTPFSSPQQTTNPAGLA 180 Query 181 AQAAAVSQATDP--------LSLLIETVTQALQALT-IPSFIPEDFTFLDAIFAGYATVG 231 AQ AAV+QA LS L ++QA++A T P+ +P+DFT LD I A YATVG Sbjct 181 AQNAAVTQAATNSAGNTPTALSQLSSFLSQAVEAPTGWPNILPDDFTILDGILAAYATVG 240 Query 232 VTQDVESFVAGTIGAESNLGLLNVGDENPAEVTPGDFGIGELVSATSPGGGVSASGAGGA 291 VTQD+ES AG IGAE+NLGLL ENPAE+ PG FGI +S++ G A Sbjct 241 VTQDIESICAGIIGAENNLGLLGAASENPAELAPGAFGI---------DAALSSAEKGAA 291 Query 292 ASVGNTVLASVGRANSIGQLSVPPSWAAPSTRPVSALSPAGLTTLPGTDVAEHGMPGVPG 351 AS+ + VLAS GRA SIG +SVPPSWA PS+ PVSALS AGLTTL GTDVAEHG PG+PG Sbjct 292 ASMHDAVLASAGRAGSIGPMSVPPSWATPSSTPVSALSGAGLTTLDGTDVAEHGTPGLPG 351 Query 352 VPVAAG-RASGVLPRYGVRLTVMAHPPAAG 380 VP RASGV+PRYGVRLTVM+ PPAAG Sbjct 352 VPAGTDKRASGVIPRYGVRLTVMSRPPAAG 381 >gi|224991510|ref|YP_002646199.1| PPE family protein [Mycobacterium bovis BCG str. Tokyo 172] gi|224774625|dbj|BAH27431.1| PPE family protein [Mycobacterium bovis BCG str. Tokyo 172] Length=381 Score = 399 bits (1024), Expect = 5e-109, Method: Compositional matrix adjust. Identities = 250/390 (65%), Positives = 291/390 (75%), Gaps = 19/390 (4%) Query 1 MDFALLPPEVNSARMYTGPGAGSLLAAAGGWDSLAAELATTAEAYGSVLSGLAALHWRGP 60 MD+A LPPE+NSARMY+GPG S+L AA WD+LAAELA+ AE YGSV++ L +HW GP Sbjct 1 MDYAFLPPEINSARMYSGPGPNSMLVAAASWDALAAELASAAENYGSVIARLTGMHWWGP 60 Query 61 AAESMAVTAAPYIGWLYTTAEKTQQTAIQARAAALAFEQAYAMTLPPPVVAANRIQLLAL 120 A+ SM +APY+ WL TA +T+QTA QARAAA AFEQA+AMT+PP +V ANR +L AL Sbjct 61 ASTSMLAMSAPYVEWLERTAAQTKQTATQARAAAAAFEQAHAMTVPPALVTANRAELKAL 120 Query 121 IATNFFGQNTAAIAATEAQYAEMWAQDAAAMYGYATASAAAALLTPFSPPRQTTNPAGLT 180 IA+N GQNTAAIAA EAQYAEMWAQDAAAMYGYAT SAAA LTPFS P+QTTNPAGL Sbjct 121 IASNLLGQNTAAIAAIEAQYAEMWAQDAAAMYGYATTSAAARQLTPFSSPQQTTNPAGLA 180 Query 181 AQAAAVSQATDP--------LSLLIETVTQALQALT-IPSFIPEDFTFLDAIFAGYATVG 231 AQ AAV+QA LS L ++QA++A T P+ +P+DFT LD I A YATVG Sbjct 181 AQNAAVTQAATNSAGNTPTALSQLSSFLSQAVEAPTGWPNILPDDFTILDGILAAYATVG 240 Query 232 VTQDVESFVAGTIGAESNLGLLNVGDENPAEVTPGDFGIGELVSATSPGGGVSASGAGGA 291 VTQD+ES AG IGA +NLGLL ENPAE+ PG FGI +S++ G A Sbjct 241 VTQDIESICAGIIGAGNNLGLLGAASENPAELAPGAFGI---------DAALSSAEKGAA 291 Query 292 ASVGNTVLASVGRANSIGQLSVPPSWAAPSTRPVSALSPAGLTTLPGTDVAEHGMPGVPG 351 AS+ + VLAS GRA SIG +SVPPSWA PS+ PVSALS AGLTTL GTDVAEHG PG+PG Sbjct 292 ASMHDAVLASAGRAGSIGPMSVPPSWATPSSTPVSALSGAGLTTLDGTDVAEHGTPGLPG 351 Query 352 VPVAAG-RASGVLPRYGVRLTVMAHPPAAG 380 VP RASGV+PRYGVRLTVM+ PPAAG Sbjct 352 VPAGTDKRASGVIPRYGVRLTVMSRPPAAG 381 >gi|240168614|ref|ZP_04747273.1| PPE family protein, PPE51_2 [Mycobacterium kansasii ATCC 12478] Length=378 Score = 395 bits (1015), Expect = 6e-108, Method: Compositional matrix adjust. Identities = 255/392 (66%), Positives = 289/392 (74%), Gaps = 26/392 (6%) Query 1 MDFALLPPEVNSARMYTGPGAGSLLAAAGGWDSLAAELATTAEAYGSVLSGLAALHWRGP 60 MDFALLPPEVNS R+YTGPG GSLLAAAG WD+LA EL TTA+ Y SV+SGL L W GP Sbjct 1 MDFALLPPEVNSGRIYTGPGPGSLLAAAGSWDALATELDTTAQTYESVVSGLTTLDWYGP 60 Query 61 AAESMAVTAAPYIGWLYTTAEKTQQTAIQARAAALAFEQAYAMTLPPPVVAANRIQLLAL 120 A+ESMA APY+ WLYTTA +T+QTA+QARAAA AF+QA+AMT+PPP +AANRIQL+AL Sbjct 61 ASESMAAKVAPYVSWLYTTATQTKQTAMQARAAAAAFDQAFAMTVPPPAIAANRIQLMAL 120 Query 121 IATNFFGQNTAAIAATEAQYAEMWAQDAAAMYGYATASAAAALLTPFSPPRQTTNPAGL- 179 IATNFFGQNTAAIAATEAQYAEMWAQDAAAMYGYAT+S AAA L PF P QTT+PAGL Sbjct 121 IATNFFGQNTAAIAATEAQYAEMWAQDAAAMYGYATSSTAAAQLMPFPSPSQTTDPAGLS 180 Query 180 -----TAQAAAVSQATDPLSLLIETVTQALQALT---IPSFIPEDFTFLDAIFAGYATVG 231 AQA A + ATDP+S L+ V+Q+L AL+ IP+F+P D+ LD IFA YAT Sbjct 181 AQSAAVAQANASAAATDPISQLVAAVSQSLGALSGLQIPNFLPADYAVLDGIFAIYATFS 240 Query 232 VTQDVESFVAGTIGAESNL--GLLNVGDENPAEVTPGDFGIGELVSATSPGGGVSASGAG 289 VES G IG E+ L L + + PAE + LV+A P G S G Sbjct 241 AIDSVESIADGIIGDEAALVPALTSATEAMPAEAS-------TLVAAQQPVGAGSGLGP- 292 Query 290 GAASVGNTVLASVGRANSIGQLSVPPSWAAPSTRPVSALSPAGLTTLPGTDVAEHGMPGV 349 N VLAS GRA SIGQLSVP SWAAP+TR VSALSPAGLTT+PGT+ A G PGV Sbjct 293 ------NAVLASAGRAGSIGQLSVPASWAAPATRTVSALSPAGLTTIPGTEEAGAGAPGV 346 Query 350 PGVPV-AAGRASGVLPRYGVRLTVMAHPPAAG 380 PG+ V A RASGVLPRYGVRLTVMAHPPAAG Sbjct 347 PGMAVPAQSRASGVLPRYGVRLTVMAHPPAAG 378 >gi|240168615|ref|ZP_04747274.1| PPE family protein [Mycobacterium kansasii ATCC 12478] Length=379 Score = 391 bits (1004), Expect = 1e-106, Method: Compositional matrix adjust. Identities = 235/391 (61%), Positives = 285/391 (73%), Gaps = 23/391 (5%) Query 1 MDFALLPPEVNSARMYTGPGAGSLLAAAGGWDSLAAELATTAEAYGSVLSGLAALHWRGP 60 MD+A LPPE+NSAR+Y+GPG GSLLAAA GWD++A EL + A Y SV+S L A++W GP Sbjct 1 MDYAFLPPEINSARIYSGPGPGSLLAAARGWDAVATELTSAAVGYRSVISSLTAMYWWGP 60 Query 61 AAESMAVTAAPYIGWLYTTAEKTQQTAIQARAAALAFEQAYAMTLPPPVVAANRIQLLAL 120 A+ SM TA P++ WL TTA + +++A Q+RAAA AFEQA+AMT+PP VVAANR QL AL Sbjct 61 ASVSMLATAGPFVEWLETTAAQAKESADQSRAAAAAFEQAHAMTVPPAVVAANRTQLKAL 120 Query 121 IATNFFGQNTAAIAATEAQYAEMWAQDAAAMYGYATASAAAALLTPFSPPRQTTNPAGLT 180 IA+NFFGQNTAAIAATEAQYAEMWAQDAAAMYGYA+ SAAA LTPFS P + +P G+ Sbjct 121 IASNFFGQNTAAIAATEAQYAEMWAQDAAAMYGYASNSAAATALTPFSSPELSVDPDGVV 180 Query 181 AQAA---------AVSQATDPLSLLIETVTQALQAL-TIPSFIPEDFTFLDAIFAGYATV 230 AQ+A + LS L +ALQA+ P+ +P+DFT LDAIFA YATV Sbjct 181 AQSAAVSQAAGGGSAGNTATVLSWLASLAPEALQAVQDWPNILPDDFTILDAIFAVYATV 240 Query 231 GVTQDVESFVAGTIGAESNLGLLNVGDENPAEVTPGDFGIGELVSATSPGGGVSASGAGG 290 GV+QDVESF AG IGAE NLGL ENPAE+ P G+ + SA S++GAG Sbjct 241 GVSQDVESFAAGIIGAEDNLGLFGT-TENPAELLPA--GLSPVFSAAE-----SSTGAG- 291 Query 291 AASVGNTVLASVGRANSIGQLSVPPSWAAPSTRPVSALSPAGLTTLPGTDVAEHGMPGVP 350 + + V AS+ RA SIG LSVP SW APST PV+ALS +GLTT+PGT+V +HG+PGVP Sbjct 292 ---LSSVVTASMSRAGSIGPLSVPASWTAPSTGPVTALSGSGLTTIPGTEVPDHGLPGVP 348 Query 351 GVPVAA-GRASGVLPRYGVRLTVMAHPPAAG 380 G+P RAS V+PRYGVRLTVM+ PPAAG Sbjct 349 GMPAGTLKRASSVVPRYGVRLTVMSRPPAAG 379 >gi|183981529|ref|YP_001849820.1| PPE family protein, PPE51_1 [Mycobacterium marinum M] gi|183174855|gb|ACC39965.1| PPE family protein, PPE51_1 [Mycobacterium marinum M] Length=381 Score = 355 bits (912), Expect = 6e-96, Method: Compositional matrix adjust. Identities = 236/390 (61%), Positives = 277/390 (72%), Gaps = 19/390 (4%) Query 1 MDFALLPPEVNSARMYTGPGAGSLLAAAGGWDSLAAELATTAEAYGSVLSGLAALHWRGP 60 M++A LPPEVNSARMY+GPG+ SLLAAA WD +A ELA+ AE Y SV+S L+ ++W GP Sbjct 1 MNYAFLPPEVNSARMYSGPGSASLLAAAASWDMVAIELASAAEGYRSVISTLSGMYWWGP 60 Query 61 AAESMAVTAAPYIGWLYTTAEKTQQTAIQARAAALAFEQAYAMTLPPPVVAANRIQLLAL 120 A+ +M P+I WL T +TA QA AAA A+EQAYAMT+PP VVAANR L+AL Sbjct 61 ASAAMLAATGPFIDWLEITGALASETANQAAAAAAAYEQAYAMTVPPIVVAANRALLVAL 120 Query 121 IATNFFGQNTAAIAATEAQYAEMWAQDAAAMYGYATASAAAALLTPFSPPRQTTNPAGLT 180 +A+NFFGQNTAAI ATEA+YAEMWAQDA AMY YA SA A L PFS P Q TNPAGL Sbjct 121 VASNFFGQNTAAIEATEAEYAEMWAQDAGAMYDYAATSAMATALVPFSAPGQDTNPAGLA 180 Query 181 AQAA--------AVSQATDPLSLLIETVTQALQALT-IPSFIPEDFTFLDAIFAGYATVG 231 AQ+A A + A S L V AL +L+ P+ +P+DF+ LD IFA YATVG Sbjct 181 AQSAAVSQAAGNAPASAQSVWSQLTSLVPDALPSLSNWPNILPDDFSILDGIFAMYATVG 240 Query 232 VTQDVESFVAGTIGAESNLGLLNVGDENPAEVTPGDFGIGELVSATSPGGGVSASGAGGA 291 VTQDVESF AG IGAE+NLGLL ENPAEVTPG G+G + S+ S GGA Sbjct 241 VTQDVESFCAGIIGAENNLGLLGAASENPAEVTPGALGLGAMFSS------AERSAVGGA 294 Query 292 ASVGNTVLASVGRANSIGQLSVPPSWAAPSTRPVSALSPAGLTTLPGTDVAEHGMPGVPG 351 N V S+ RA SIGQLSVPPSWAAPS+ SALS +GLTT+PGT+VAE G PG+PG Sbjct 295 T---NAVTVSMSRAGSIGQLSVPPSWAAPSSGSASALSVSGLTTIPGTEVAEQGAPGMPG 351 Query 352 VPVAAG-RASGVLPRYGVRLTVMAHPPAAG 380 +PV G RA+ V+PRYGVRLTVMA PPAAG Sbjct 352 MPVGTGKRATSVIPRYGVRLTVMARPPAAG 381 >gi|118618187|ref|YP_906519.1| PPE family protein [Mycobacterium ulcerans Agy99] gi|118570297|gb|ABL05048.1| PPE family protein [Mycobacterium ulcerans Agy99] Length=381 Score = 350 bits (897), Expect = 3e-94, Method: Compositional matrix adjust. Identities = 234/390 (60%), Positives = 275/390 (71%), Gaps = 19/390 (4%) Query 1 MDFALLPPEVNSARMYTGPGAGSLLAAAGGWDSLAAELATTAEAYGSVLSGLAALHWRGP 60 M++A LPPEVNSARMY+GPG+ SLLAAA WD +A ELA+ AE Y SV+S L+ ++W GP Sbjct 1 MNYAFLPPEVNSARMYSGPGSASLLAAAASWDMVAIELASAAEGYRSVISTLSGMYWWGP 60 Query 61 AAESMAVTAAPYIGWLYTTAEKTQQTAIQARAAALAFEQAYAMTLPPPVVAANRIQLLAL 120 A+ +M P+IGWL T +TA QA AAA A+EQAYAMT+PP VVAANR L+AL Sbjct 61 ASAAMLAATGPFIGWLEITGALASETANQAAAAAAAYEQAYAMTVPPIVVAANRALLVAL 120 Query 121 IATNFFGQNTAAIAATEAQYAEMWAQDAAAMYGYATASAAAALLTPFSPPRQTTNPAGLT 180 +A+N FGQNTAAI ATEA+YAEMWAQDA AMY YA SA A L PFS P Q TNPAGL Sbjct 121 VASNIFGQNTAAIEATEAEYAEMWAQDAGAMYDYAATSAMATALVPFSAPGQDTNPAGLA 180 Query 181 AQAA--------AVSQATDPLSLLIETVTQALQALT-IPSFIPEDFTFLDAIFAGYATVG 231 AQ+A A + A S L V AL +L+ P+ +P+DF+ LD IFA YATVG Sbjct 181 AQSAAVSQAAGNAPASAQSVWSQLTSLVPDALPSLSNWPNILPDDFSMLDGIFAMYATVG 240 Query 232 VTQDVESFVAGTIGAESNLGLLNVGDENPAEVTPGDFGIGELVSATSPGGGVSASGAGGA 291 VTQDVESF AG IGA +NLGLL EN AEVTPG G+G + S+ S GGA Sbjct 241 VTQDVESFCAGIIGAGNNLGLLGAASENSAEVTPGALGLGAMFSS------AERSAVGGA 294 Query 292 ASVGNTVLASVGRANSIGQLSVPPSWAAPSTRPVSALSPAGLTTLPGTDVAEHGMPGVPG 351 N V S+ RA SIGQLSVPPSWAAPS+ SALS +GLTT+PGT+VAE G PG+PG Sbjct 295 T---NAVTVSMSRAGSIGQLSVPPSWAAPSSGSASALSVSGLTTIPGTEVAEQGAPGMPG 351 Query 352 VPVAAG-RASGVLPRYGVRLTVMAHPPAAG 380 +PV G RA+ V+PRYGVRLTVMA PPAAG Sbjct 352 MPVGTGKRATSVIPRYGVRLTVMARPPAAG 381 >gi|118617918|ref|YP_906250.1| PPE family protein [Mycobacterium ulcerans Agy99] gi|118570028|gb|ABL04779.1| PPE family protein [Mycobacterium ulcerans Agy99] Length=381 Score = 346 bits (888), Expect = 3e-93, Method: Compositional matrix adjust. Identities = 233/390 (60%), Positives = 274/390 (71%), Gaps = 19/390 (4%) Query 1 MDFALLPPEVNSARMYTGPGAGSLLAAAGGWDSLAAELATTAEAYGSVLSGLAALHWRGP 60 M++A LPPEVNSARMY+GPG+ SLLAAA WD +A ELA+ AE Y SV+S L+ ++W GP Sbjct 1 MNYAFLPPEVNSARMYSGPGSASLLAAAASWDMVAIELASAAEGYRSVISTLSGMYWWGP 60 Query 61 AAESMAVTAAPYIGWLYTTAEKTQQTAIQARAAALAFEQAYAMTLPPPVVAANRIQLLAL 120 A+ +M P+IGWL T +TA QA AAA A+EQAYAMT+PP VVAANR L+AL Sbjct 61 ASAAMLAATGPFIGWLEITGALASETANQAAAAAAAYEQAYAMTVPPIVVAANRALLVAL 120 Query 121 IATNFFGQNTAAIAATEAQYAEMWAQDAAAMYGYATASAAAALLTPFSPPRQTTNPAGLT 180 +A+N FGQNTAAI ATEA+YAEMWAQDA AMY YA SA A L PFS P Q TNPAGL Sbjct 121 VASNIFGQNTAAIEATEAEYAEMWAQDAGAMYDYAATSAMATALVPFSAPGQDTNPAGLA 180 Query 181 AQAA--------AVSQATDPLSLLIETVTQALQALT-IPSFIPEDFTFLDAIFAGYATVG 231 AQ+A A + A S L V AL +L+ P+ +P+DF+ LD IFA YATVG Sbjct 181 AQSAAVSQAAGNAPASAQSVWSQLTSLVPDALPSLSNWPNILPDDFSMLDGIFAMYATVG 240 Query 232 VTQDVESFVAGTIGAESNLGLLNVGDENPAEVTPGDFGIGELVSATSPGGGVSASGAGGA 291 VTQDVESF AG IGA +NLGLL EN AEVTPG G+G + S+ S GGA Sbjct 241 VTQDVESFCAGIIGAGNNLGLLGAASENSAEVTPGALGLGAMFSS------AERSAVGGA 294 Query 292 ASVGNTVLASVGRANSIGQLSVPPSWAAPSTRPVSALSPAGLTTLPGTDVAEHGMPGVPG 351 N V S+ RA SIGQLSVPPSWAAPS+ SALS +GLTT+PGT+VAE G PG+PG Sbjct 295 T---NAVTVSMSRAGSIGQLSVPPSWAAPSSGSASALSVSGLTTIPGTEVAEQGAPGMPG 351 Query 352 VPVAAG-RASGVLPRYGVRLTVMAHPPAAG 380 +PV G RA+ V+ RYGVRLTVMA PPAAG Sbjct 352 MPVGTGKRATSVILRYGVRLTVMARPPAAG 381 >gi|289448814|ref|ZP_06438558.1| PPE family protein [Mycobacterium tuberculosis CPHL_A] gi|289421772|gb|EFD18973.1| PPE family protein [Mycobacterium tuberculosis CPHL_A] Length=387 Score = 342 bits (876), Expect = 8e-92, Method: Compositional matrix adjust. Identities = 220/348 (64%), Positives = 258/348 (75%), Gaps = 18/348 (5%) Query 1 MDFALLPPEVNSARMYTGPGAGSLLAAAGGWDSLAAELATTAEAYGSVLSGLAALHWRGP 60 MD+A LPPE+NSARMY+GPG S+L AA WD+LAAELA+ AE YGSV++ L +HW GP Sbjct 1 MDYAFLPPEINSARMYSGPGPNSMLVAAASWDALAAELASAAENYGSVIARLTGMHWWGP 60 Query 61 AAESMAVTAAPYIGWLYTTAEKTQQTAIQARAAALAFEQAYAMTLPPPVVAANRIQLLAL 120 A+ SM +APY+ WL TA +T+QTA QARAAA AFEQA+AMT+PP +V ANR +L AL Sbjct 61 ASTSMLAMSAPYVEWLERTAAQTKQTATQARAAAAAFEQAHAMTVPPALVTANRAELKAL 120 Query 121 IATNFFGQNTAAIAATEAQYAEMWAQDAAAMYGYATASAAAALLTPFSPPRQTTNPAGLT 180 IA+N GQNTAAIAA EAQYAEMWAQDAAAMYGYAT SAAA LTPFS P+QTTNPAGL Sbjct 121 IASNLLGQNTAAIAAIEAQYAEMWAQDAAAMYGYATTSAAARQLTPFSSPQQTTNPAGLA 180 Query 181 AQAAAVSQATDP--------LSLLIETVTQALQALT-IPSFIPEDFTFLDAIFAGYATVG 231 AQ AAV+QA LS L ++QA++A T P+ +P+DFT LD IFA YATVG Sbjct 181 AQNAAVTQAATNSAGNTPTALSQLSSFLSQAVEAPTGWPNILPDDFTILDGIFAAYATVG 240 Query 232 VTQDVESFVAGTIGAESNLGLLNVGDENPAEVTPGDFGIGELVSATSPGGGVSASGAGGA 291 VTQD+ES AG IGAE+NLGLL ENPAE+ PG FGI +S++ G A Sbjct 241 VTQDIESICAGIIGAENNLGLLGAASENPAELAPGAFGI---------DAALSSAEKGAA 291 Query 292 ASVGNTVLASVGRANSIGQLSVPPSWAAPSTRPVSALSPAGLTTLPGT 339 AS+ + VLAS GRA SIG +SVPPSWA PS+ PVSALS AGLTTL GT Sbjct 292 ASMHDAVLASAGRAGSIGPMSVPPSWATPSSTPVSALSGAGLTTLDGT 339 >gi|183983449|ref|YP_001851740.1| PPE family protein, PPE51_3 [Mycobacterium marinum M] gi|183176775|gb|ACC41885.1| PPE family protein, PPE51_3 [Mycobacterium marinum M] Length=380 Score = 331 bits (849), Expect = 1e-88, Method: Compositional matrix adjust. Identities = 230/389 (60%), Positives = 269/389 (70%), Gaps = 18/389 (4%) Query 1 MDFALLPPEVNSARMYTGPGAGSLLAAAGGWDSLAAELATTAEAYGSVLSGLAALHWRGP 60 M++A LPPEVNSARMY+GPG SLLAAA WD +A ELA+TAE Y SV+S L+ ++W GP Sbjct 1 MNYAFLPPEVNSARMYSGPGPESLLAAAASWDMVAIELASTAEGYRSVISTLSGMYWWGP 60 Query 61 AAESMAVTAAPYIGWLYTTAEKTQQTAIQARAAALAFEQAYAMTLPPPVVAANRIQLLAL 120 A+ +M P+I WL T +TA QA AAA A+EQAYAMT+PP VVAANR L AL Sbjct 61 ASAAMLAATGPFIDWLEITGALASETANQATAAAAAYEQAYAMTVPPIVVAANRALLAAL 120 Query 121 IATNFFGQNTAAIAATEAQYAEMWAQDAAAMYGYATASAAAALLTPFSPPRQTTNPAGLT 180 IA+N FGQNTAAI ATEA+YAEMWAQDA AMY YA SA A L PF P+Q TNPAGL Sbjct 121 IASNIFGQNTAAIEATEAEYAEMWAQDAGAMYDYAATSAMATALEPFPGPQQHTNPAGLP 180 Query 181 AQAAAVSQ--------ATDPLSLLIETVTQALQALTIPSFIPEDFTFLDAIFAGYATVGV 232 AQ AAVS+ + LS LI V QALQ L I +PE+FT LDAIFA YATVG+ Sbjct 181 AQGAAVSKAAASSEEGSQSLLSQLIALVPQALQVLGIWPILPEEFTLLDAIFAMYATVGM 240 Query 233 TQDVESFVAGTIGAESNLGLLNVGDENPAEVTPGDFGIGELVSATSPGGGVSASGAGGAA 292 T D + I A++NLGLL ENPAE+ PG G+ G +S++ G A Sbjct 241 TADAVTIPVAIIAADNNLGLLGAASENPAELAPGALGV---------GAKLSSAEMGAAR 291 Query 293 SVGNTVLASVGRANSIGQLSVPPSWAAPSTRPVSALSPAGLTTLPGTDVAEHGMPGVPGV 352 N V S+ RA SIGQLSVPPSWAAPS+ SALS +GLTT+PGT+VAE G PGVPG+ Sbjct 292 GAANAVTVSMSRAGSIGQLSVPPSWAAPSSGSASALSVSGLTTIPGTEVAEQGAPGVPGM 351 Query 353 PVAAG-RASGVLPRYGVRLTVMAHPPAAG 380 PV G RA+ V+PRYGVRLTVMA PPAAG Sbjct 352 PVGTGKRATSVIPRYGVRLTVMARPPAAG 380 >gi|289575846|ref|ZP_06456073.1| PPE family protein [Mycobacterium tuberculosis K85] gi|339633142|ref|YP_004724784.1| PPE family protein [Mycobacterium africanum GM041182] gi|289540277|gb|EFD44855.1| PPE family protein [Mycobacterium tuberculosis K85] gi|339332498|emb|CCC28213.1| PPE family protein [Mycobacterium africanum GM041182] Length=345 Score = 316 bits (809), Expect = 4e-84, Method: Compositional matrix adjust. Identities = 204/327 (63%), Positives = 241/327 (74%), Gaps = 18/327 (5%) Query 1 MDFALLPPEVNSARMYTGPGAGSLLAAAGGWDSLAAELATTAEAYGSVLSGLAALHWRGP 60 MD+A LPPE+NSARMY+GPG S+L AA WD+LAAELA+ AE YGSV++ L +HW GP Sbjct 1 MDYAFLPPEINSARMYSGPGPNSMLVAAASWDALAAELASAAENYGSVIARLTGMHWWGP 60 Query 61 AAESMAVTAAPYIGWLYTTAEKTQQTAIQARAAALAFEQAYAMTLPPPVVAANRIQLLAL 120 A+ SM +APY+ WL TA +T+QTA QARAAA AFEQA+AMT+PP +V ANR +L AL Sbjct 61 ASTSMLAMSAPYVEWLERTAAQTKQTATQARAAAAAFEQAHAMTVPPALVTANRAELKAL 120 Query 121 IATNFFGQNTAAIAATEAQYAEMWAQDAAAMYGYATASAAAALLTPFSPPRQTTNPAGLT 180 IA+N GQNTAAIAA EAQYAEMWAQDAAAMYGYAT SAAA LTPFS P+QTTNPAGL Sbjct 121 IASNLLGQNTAAIAAIEAQYAEMWAQDAAAMYGYATTSAAARQLTPFSSPQQTTNPAGLA 180 Query 181 AQAAAVSQATDP--------LSLLIETVTQALQALT-IPSFIPEDFTFLDAIFAGYATVG 231 AQ AAV+QA LS L ++QA++A T P+ +P+DFT LD IFA YATVG Sbjct 181 AQNAAVTQAATNSAGNTPTALSQLSSFLSQAVEAPTGWPNILPDDFTILDGIFAAYATVG 240 Query 232 VTQDVESFVAGTIGAESNLGLLNVGDENPAEVTPGDFGIGELVSATSPGGGVSASGAGGA 291 VTQD+ES AG IGAE+NLGLL ENPAE+ PG FGI +S++ G A Sbjct 241 VTQDIESICAGIIGAENNLGLLGAASENPAELAPGAFGI---------DAALSSAEKGAA 291 Query 292 ASVGNTVLASVGRANSIGQLSVPPSWA 318 AS+ + VLAS GRA SIG +SVPPSWA Sbjct 292 ASMHDAVLASAGRAGSIGPMSVPPSWA 318 >gi|298527010|ref|ZP_07014419.1| ppe family protein [Mycobacterium tuberculosis 94_M4241A] gi|298496804|gb|EFI32098.1| ppe family protein [Mycobacterium tuberculosis 94_M4241A] Length=405 Score = 311 bits (796), Expect = 2e-82, Method: Compositional matrix adjust. Identities = 191/407 (47%), Positives = 244/407 (60%), Gaps = 31/407 (7%) Query 1 MDFALLPPEVNSARMYTGPGAGSLLAAAGGWDSLAAELATTAEAYGSVLSGLAALHWRGP 60 MDFA+LPPEVNS RMY+GPGAGSL AAA WD ++AEL + AE Y SV++ L W GP Sbjct 3 MDFAMLPPEVNSTRMYSGPGAGSLWAAAA-WDQVSAELQSAAETYRSVIASLTGWQWLGP 61 Query 61 AAESMAVTAAPYIGWLYTTAEKTQQTAIQARAAALAFEQAYAMTLPPPVVAANRIQLLAL 120 ++ M PY+ WL TTA + +QTA Q AAA FEQA+AMT+PPP + ANR Q+L+L Sbjct 62 SSVRMGAAVTPYVEWLTTTAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVLSL 121 Query 121 IATNFFGQNTAAIAATEAQYAEMWAQDAAAMYGYATASAAAALLTPFSPPRQTTNPAGLT 180 IATNFFGQNTAAIAA E QYAEMW QDA AMY YA SAAA LTPF+ P+Q TN AGL Sbjct 122 IATNFFGQNTAAIAALETQYAEMWEQDATAMYDYAATSAAARTLTPFTSPQQDTNSAGLP 181 Query 181 AQAAAVSQAT--------------------------DPLSLLIETVTQALQALTIPSFIP 214 AQ+A VS+AT L+ + + A+ PS + Sbjct 182 AQSAEVSRATANAGAADGNWLGNLLEEIGILLLPIAPELTPFFLEAGEIVNAIPFPSIVG 241 Query 215 EDFTFLDAIFAGYATVGVTQDVESFVAGTIGAESNLGLL-NVGDENPAEVTPGDFGIGEL 273 ++F LD + A YAT+G ++ S G IGAE NLG+L +G A P Sbjct 242 DEFCLLDGLLAWYATIGSINNINSMGTGIIGAEKNLGILPELGSAAAAAAPPPADIAPAF 301 Query 274 VSATSPGGGVSASGAGGAASVGNTVLASVGRANSIGQLSVPPSWAAPSTRPVSALSPAGL 333 + +P ++ S + GA V A++ A +IGQ+SVPP+W AP+ V A + Sbjct 302 L---APLTSMAKSLSDGALRGPGEVSAAMRGAGTIGQMSVPPAWKAPAVTTVRAFDATPM 358 Query 334 TTLPGTDVAEHGMPGVPGVPVAAGRASGVLPRYGVRLTVMAHPPAAG 380 TTLPG D G+PG+PG+P + +GV+PRYGVRLTVM P + G Sbjct 359 TTLPGGDAPAAGVPGLPGMPASGAGRAGVVPRYGVRLTVMTRPLSGG 405 >gi|289755661|ref|ZP_06515039.1| PPE family protein [Mycobacterium tuberculosis EAS054] gi|289696248|gb|EFD63677.1| PPE family protein [Mycobacterium tuberculosis EAS054] Length=405 Score = 309 bits (791), Expect = 6e-82, Method: Compositional matrix adjust. Identities = 190/407 (47%), Positives = 243/407 (60%), Gaps = 31/407 (7%) Query 1 MDFALLPPEVNSARMYTGPGAGSLLAAAGGWDSLAAELATTAEAYGSVLSGLAALHWRGP 60 MDFA+LPPEVNS RMY+GPGAGSL AAA WD ++AEL + AE Y SV++ L W GP Sbjct 3 MDFAMLPPEVNSTRMYSGPGAGSLWAAAA-WDQVSAELQSAAETYRSVIASLTGWQWLGP 61 Query 61 AAESMAVTAAPYIGWLYTTAEKTQQTAIQARAAALAFEQAYAMTLPPPVVAANRIQLLAL 120 ++ M PY+ WL TTA + +QTA Q AAA FEQA+AMT+PPP + ANR Q+L+L Sbjct 62 SSVRMGAAVTPYVEWLTTTAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVLSL 121 Query 121 IATNFFGQNTAAIAATEAQYAEMWAQDAAAMYGYATASAAAALLTPFSPPRQTTNPAGLT 180 IATNFFGQNTAAIAA E QYAEMW QDA AMY YA SAAA LTPF+ P+Q TN AGL Sbjct 122 IATNFFGQNTAAIAALETQYAEMWEQDATAMYDYAATSAAARTLTPFTSPQQDTNSAGLP 181 Query 181 AQAAAVSQAT--------------------------DPLSLLIETVTQALQALTIPSFIP 214 AQ+A VS+AT L+ + + A+ PS + Sbjct 182 AQSAEVSRATANAGAADGNWLGNLLEEIGILLLPIAPELTPFFLEAGEIVNAIPFPSIVG 241 Query 215 EDFTFLDAIFAGYATVGVTQDVESFVAGTIGAESNLGLL-NVGDENPAEVTPGDFGIGEL 273 ++F LD + A YA +G ++ S G IGAE NLG+L +G A P Sbjct 242 DEFCLLDGLLAWYAMIGSINNINSMGTGIIGAEKNLGILPELGSAAAAAAPPPADIAPAF 301 Query 274 VSATSPGGGVSASGAGGAASVGNTVLASVGRANSIGQLSVPPSWAAPSTRPVSALSPAGL 333 + +P ++ S + GA V A++ A +IGQ+SVPP+W AP+ V A + Sbjct 302 L---APLTSMAKSLSDGALRGPGEVSAAMRGAGTIGQMSVPPAWKAPAVTTVRAFDATPM 358 Query 334 TTLPGTDVAEHGMPGVPGVPVAAGRASGVLPRYGVRLTVMAHPPAAG 380 TTLPG D G+PG+PG+P + +GV+PRYGVRLTVM P + G Sbjct 359 TTLPGGDAPAAGVPGLPGMPASGAGRAGVVPRYGVRLTVMTRPLSGG 405 >gi|289572184|ref|ZP_06452411.1| PPE family protein [Mycobacterium tuberculosis K85] gi|289536615|gb|EFD41193.1| PPE family protein [Mycobacterium tuberculosis K85] Length=406 Score = 307 bits (786), Expect = 2e-81, Method: Compositional matrix adjust. Identities = 192/407 (48%), Positives = 245/407 (61%), Gaps = 30/407 (7%) Query 1 MDFALLPPEVNSARMYTGPGAGSLLAAAGGWDSLAAELATTAEAYGSVLSGLAALHWRGP 60 MDFA+LPPEVNS RMY+GPGAGSL AAA WD ++AEL + AE Y SV++ L W GP Sbjct 3 MDFAMLPPEVNSTRMYSGPGAGSLWAAAAAWDQVSAELQSAAETYRSVIASLTGWQWLGP 62 Query 61 AAESMAVTAAPYIGWLYTTAEKTQQTAIQARAAALAFEQAYAMTLPPPVVAANRIQLLAL 120 ++ M PY+ WL TTA + +QTA Q AAA FEQA+AMT+PPP + ANR Q+L+L Sbjct 63 SSVRMGAAVTPYVEWLTTTAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVLSL 122 Query 121 IATNFFGQNTAAIAATEAQYAEMWAQDAAAMYGYATASAAAALLTPFSPPRQTTNPAGLT 180 IATNFFGQNTAAIAA E QYAEMW QDA AMY YA SAAA LTPF+ P+Q TN AGL Sbjct 123 IATNFFGQNTAAIAALETQYAEMWEQDATAMYDYAATSAAARTLTPFTSPQQDTNSAGLP 182 Query 181 AQAAAVSQAT--------------------------DPLSLLIETVTQALQALTIPSFIP 214 AQ+A VS+AT L+ + + A+ PS + Sbjct 183 AQSAEVSRATANAGAADGNWLGNLLEEIGILLLPIAPELTPFFLEAGEIVNAIPFPSIVG 242 Query 215 EDFTFLDAIFAGYATVGVTQDVESFVAGTIGAESNLGLL-NVGDENPAEVTPGDFGIGEL 273 ++F LD + A YAT+G ++ S G IGAE NLG+L +G A P Sbjct 243 DEFCLLDGLLAWYATIGSINNINSMGTGIIGAEKNLGILPELGSAAAAAAPPPADIAPAF 302 Query 274 VSATSPGGGVSASGAGGAASVGNTVLASVGRANSIGQLSVPPSWAAPSTRPVSALSPAGL 333 + +P ++ S + GA V A++ A +IGQ+SVPP+W AP+ V A + Sbjct 303 L---APLTSMAKSLSDGALRGPGEVSAAMRGAGTIGQMSVPPAWKAPAVTTVRAFDATPM 359 Query 334 TTLPGTDVAEHGMPGVPGVPVAAGRASGVLPRYGVRLTVMAHPPAAG 380 TTLPG DV G+PG+PG+P + +GV+PRYGVRLTVM P + G Sbjct 360 TTLPGGDVPAAGVPGLPGMPASGAGRAGVVPRYGVRLTVMTRPLSGG 406 >gi|31794708|ref|NP_857201.1| PPE family protein [Mycobacterium bovis AF2122/97] gi|57117120|ref|YP_177984.1| PPE family protein [Mycobacterium tuberculosis H37Rv] gi|121639451|ref|YP_979675.1| PPE family protein [Mycobacterium bovis BCG str. Pasteur 1173P2] 50 more sequence titles Length=406 Score = 305 bits (781), Expect = 8e-81, Method: Compositional matrix adjust. Identities = 191/407 (47%), Positives = 244/407 (60%), Gaps = 30/407 (7%) Query 1 MDFALLPPEVNSARMYTGPGAGSLLAAAGGWDSLAAELATTAEAYGSVLSGLAALHWRGP 60 MDFA+LPPEVNS RMY+GPGAGSL AAA WD ++AEL + AE Y SV++ L W GP Sbjct 3 MDFAMLPPEVNSTRMYSGPGAGSLWAAAAAWDQVSAELQSAAETYRSVIASLTGWQWLGP 62 Query 61 AAESMAVTAAPYIGWLYTTAEKTQQTAIQARAAALAFEQAYAMTLPPPVVAANRIQLLAL 120 ++ M PY+ WL TTA + +QTA Q AAA FEQA+AMT+PPP + ANR Q+L+L Sbjct 63 SSVRMGAAVTPYVEWLTTTAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVLSL 122 Query 121 IATNFFGQNTAAIAATEAQYAEMWAQDAAAMYGYATASAAAALLTPFSPPRQTTNPAGLT 180 IATNFFGQNTAAIAA E QYAEMW QDA AMY YA SAAA LTPF+ P+Q TN AGL Sbjct 123 IATNFFGQNTAAIAALETQYAEMWEQDATAMYDYAATSAAARTLTPFTSPQQDTNSAGLP 182 Query 181 AQAAAVSQAT--------------------------DPLSLLIETVTQALQALTIPSFIP 214 AQ+A VS+AT L+ + + A+ PS + Sbjct 183 AQSAEVSRATANAGAADGNWLGNLLEEIGILLLPIAPELTPFFLEAGEIVNAIPFPSIVG 242 Query 215 EDFTFLDAIFAGYATVGVTQDVESFVAGTIGAESNLGLL-NVGDENPAEVTPGDFGIGEL 273 ++F LD + A YAT+G ++ S G IGAE NLG+L +G A P Sbjct 243 DEFCLLDGLLAWYATIGSINNINSMGTGIIGAEKNLGILPELGSAAAAAAPPPADIAPAF 302 Query 274 VSATSPGGGVSASGAGGAASVGNTVLASVGRANSIGQLSVPPSWAAPSTRPVSALSPAGL 333 + +P ++ S + GA V A++ A +IGQ+SVPP+W AP+ V A + Sbjct 303 L---APLTSMAKSLSDGALRGPGEVSAAMRGAGTIGQMSVPPAWKAPAVTTVRAFDATPM 359 Query 334 TTLPGTDVAEHGMPGVPGVPVAAGRASGVLPRYGVRLTVMAHPPAAG 380 TTLPG D G+PG+PG+P + +GV+PRYGVRLTVM P + G Sbjct 360 TTLPGGDAPAAGVPGLPGMPASGAGRAGVVPRYGVRLTVMTRPLSGG 406 >gi|308232493|ref|ZP_07416221.2| PPE family protein [Mycobacterium tuberculosis SUMu001] gi|308369156|ref|ZP_07416751.2| PPE family protein [Mycobacterium tuberculosis SUMu002] gi|308371381|ref|ZP_07424759.2| PPE family protein [Mycobacterium tuberculosis SUMu003] 9 more sequence titles Length=404 Score = 305 bits (780), Expect = 1e-80, Method: Compositional matrix adjust. Identities = 191/407 (47%), Positives = 244/407 (60%), Gaps = 30/407 (7%) Query 1 MDFALLPPEVNSARMYTGPGAGSLLAAAGGWDSLAAELATTAEAYGSVLSGLAALHWRGP 60 MDFA+LPPEVNS RMY+GPGAGSL AAA WD ++AEL + AE Y SV++ L W GP Sbjct 1 MDFAMLPPEVNSTRMYSGPGAGSLWAAAAAWDQVSAELQSAAETYRSVIASLTGWQWLGP 60 Query 61 AAESMAVTAAPYIGWLYTTAEKTQQTAIQARAAALAFEQAYAMTLPPPVVAANRIQLLAL 120 ++ M PY+ WL TTA + +QTA Q AAA FEQA+AMT+PPP + ANR Q+L+L Sbjct 61 SSVRMGAAVTPYVEWLTTTAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVLSL 120 Query 121 IATNFFGQNTAAIAATEAQYAEMWAQDAAAMYGYATASAAAALLTPFSPPRQTTNPAGLT 180 IATNFFGQNTAAIAA E QYAEMW QDA AMY YA SAAA LTPF+ P+Q TN AGL Sbjct 121 IATNFFGQNTAAIAALETQYAEMWEQDATAMYDYAATSAAARTLTPFTSPQQDTNSAGLP 180 Query 181 AQAAAVSQAT--------------------------DPLSLLIETVTQALQALTIPSFIP 214 AQ+A VS+AT L+ + + A+ PS + Sbjct 181 AQSAEVSRATANAGAADGNWLGNLLEEIGILLLPIAPELTPFFLEAGEIVNAIPFPSIVG 240 Query 215 EDFTFLDAIFAGYATVGVTQDVESFVAGTIGAESNLGLL-NVGDENPAEVTPGDFGIGEL 273 ++F LD + A YAT+G ++ S G IGAE NLG+L +G A P Sbjct 241 DEFCLLDGLLAWYATIGSINNINSMGTGIIGAEKNLGILPELGSAAAAAAPPPADIAPAF 300 Query 274 VSATSPGGGVSASGAGGAASVGNTVLASVGRANSIGQLSVPPSWAAPSTRPVSALSPAGL 333 + +P ++ S + GA V A++ A +IGQ+SVPP+W AP+ V A + Sbjct 301 L---APLTSMAKSLSDGALRGPGEVSAAMRGAGTIGQMSVPPAWKAPAVTTVRAFDATPM 357 Query 334 TTLPGTDVAEHGMPGVPGVPVAAGRASGVLPRYGVRLTVMAHPPAAG 380 TTLPG D G+PG+PG+P + +GV+PRYGVRLTVM P + G Sbjct 358 TTLPGGDAPAAGVPGLPGMPASGAGRAGVVPRYGVRLTVMTRPLSGG 404 >gi|339633530|ref|YP_004725172.1| PPE family protein [Mycobacterium africanum GM041182] gi|339332886|emb|CCC28613.1| PPE family protein [Mycobacterium africanum GM041182] Length=406 Score = 304 bits (778), Expect = 2e-80, Method: Compositional matrix adjust. Identities = 190/407 (47%), Positives = 244/407 (60%), Gaps = 30/407 (7%) Query 1 MDFALLPPEVNSARMYTGPGAGSLLAAAGGWDSLAAELATTAEAYGSVLSGLAALHWRGP 60 MDFA+LPPEVNS RMY+GPGAGSL AAA WD ++AEL + AE Y S+++ L W GP Sbjct 3 MDFAMLPPEVNSTRMYSGPGAGSLWAAAAAWDQVSAELQSAAETYRSMIASLTGWQWLGP 62 Query 61 AAESMAVTAAPYIGWLYTTAEKTQQTAIQARAAALAFEQAYAMTLPPPVVAANRIQLLAL 120 ++ M PY+ WL TTA + +QTA Q AAA FEQA+AMT+PPP + ANR Q+L+L Sbjct 63 SSVRMGAAVTPYVEWLTTTAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVLSL 122 Query 121 IATNFFGQNTAAIAATEAQYAEMWAQDAAAMYGYATASAAAALLTPFSPPRQTTNPAGLT 180 IATNFFGQNTAAIAA E QYAEMW QDA AMY YA SAAA LTPF+ P+Q TN AGL Sbjct 123 IATNFFGQNTAAIAALETQYAEMWEQDATAMYDYAATSAAARTLTPFTSPQQDTNSAGLP 182 Query 181 AQAAAVSQAT--------------------------DPLSLLIETVTQALQALTIPSFIP 214 AQ+A VS+AT L+ + + A+ PS + Sbjct 183 AQSAEVSRATANAGAADGNWLGNLLEEIGILLLPIAPELTPFFLEAGEIVNAIPFPSIVG 242 Query 215 EDFTFLDAIFAGYATVGVTQDVESFVAGTIGAESNLGLL-NVGDENPAEVTPGDFGIGEL 273 ++F LD + A YAT+G ++ S G IGAE NLG+L +G A P Sbjct 243 DEFCLLDGLLAWYATIGSINNINSMGTGIIGAEKNLGILPELGSAAAAAAPPPADIAPAF 302 Query 274 VSATSPGGGVSASGAGGAASVGNTVLASVGRANSIGQLSVPPSWAAPSTRPVSALSPAGL 333 + +P ++ S + GA V A++ A +IGQ+SVPP+W AP+ V A + Sbjct 303 L---APLTSMAKSLSDGALRGPGEVSAAMRGAGTIGQMSVPPAWKAPAVTTVRAFDATPM 359 Query 334 TTLPGTDVAEHGMPGVPGVPVAAGRASGVLPRYGVRLTVMAHPPAAG 380 TTLPG D G+PG+PG+P + +GV+PRYGVRLTVM P + G Sbjct 360 TTLPGGDAPAAGVPGLPGMPASGAGRAGVVPRYGVRLTVMTRPLSGG 406 >gi|289440961|ref|ZP_06430705.1| PPE family protein [Mycobacterium tuberculosis T46] gi|289571773|ref|ZP_06452000.1| PPE family protein [Mycobacterium tuberculosis T17] gi|289752245|ref|ZP_06511623.1| PPE family protein [Mycobacterium tuberculosis T92] gi|289413880|gb|EFD11120.1| PPE family protein [Mycobacterium tuberculosis T46] gi|289545527|gb|EFD49175.1| PPE family protein [Mycobacterium tuberculosis T17] gi|289692832|gb|EFD60261.1| PPE family protein [Mycobacterium tuberculosis T92] Length=406 Score = 303 bits (775), Expect = 4e-80, Method: Compositional matrix adjust. Identities = 190/407 (47%), Positives = 243/407 (60%), Gaps = 30/407 (7%) Query 1 MDFALLPPEVNSARMYTGPGAGSLLAAAGGWDSLAAELATTAEAYGSVLSGLAALHWRGP 60 MDFA+LPPEVNS RMY+GPGAGSL AAA WD ++AEL + AE Y SV++ L W GP Sbjct 3 MDFAMLPPEVNSTRMYSGPGAGSLWAAAAAWDQVSAELQSAAETYRSVIASLTGWQWLGP 62 Query 61 AAESMAVTAAPYIGWLYTTAEKTQQTAIQARAAALAFEQAYAMTLPPPVVAANRIQLLAL 120 ++ M PY+ WL TTA + +QTA Q AAA FEQA+AMT+PPP + ANR Q+L+L Sbjct 63 SSVRMGAAVTPYVEWLTTTAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVLSL 122 Query 121 IATNFFGQNTAAIAATEAQYAEMWAQDAAAMYGYATASAAAALLTPFSPPRQTTNPAGLT 180 IATNFFGQNTAAIAA E QYAEMW QDA AMY YA SAAA LTPF+ P+Q TN AGL Sbjct 123 IATNFFGQNTAAIAALETQYAEMWEQDATAMYDYAATSAAARTLTPFTSPQQDTNSAGLP 182 Query 181 AQAAAVSQAT--------------------------DPLSLLIETVTQALQALTIPSFIP 214 AQ+A VS+AT L+ + + A+ PS + Sbjct 183 AQSAEVSRATANAGAADGNWLGNLLEEIGILLLPIAPELTPFFLEAGEIVNAIPFPSIVG 242 Query 215 EDFTFLDAIFAGYATVGVTQDVESFVAGTIGAESNLGLL-NVGDENPAEVTPGDFGIGEL 273 ++F LD + A YA +G ++ S G IGAE NLG+L +G A P Sbjct 243 DEFCLLDGLLAWYAMIGSINNINSMGTGIIGAEKNLGILPELGSAAAAAAPPPADIAPAF 302 Query 274 VSATSPGGGVSASGAGGAASVGNTVLASVGRANSIGQLSVPPSWAAPSTRPVSALSPAGL 333 + +P ++ S + GA V A++ A +IGQ+SVPP+W AP+ V A + Sbjct 303 L---APLTSMAKSLSDGALRGPGEVSAAMRGAGTIGQMSVPPAWKAPAVTTVRAFDATPM 359 Query 334 TTLPGTDVAEHGMPGVPGVPVAAGRASGVLPRYGVRLTVMAHPPAAG 380 TTLPG D G+PG+PG+P + +GV+PRYGVRLTVM P + G Sbjct 360 TTLPGGDAPAAGVPGLPGMPASGAGRAGVVPRYGVRLTVMTRPLSGG 406 >gi|240169296|ref|ZP_04747955.1| PPE family protein [Mycobacterium kansasii ATCC 12478] Length=409 Score = 296 bits (758), Expect = 3e-78, Method: Compositional matrix adjust. Identities = 200/420 (48%), Positives = 250/420 (60%), Gaps = 52/420 (12%) Query 1 MDFALLPPEVNSARMYTGPGAGSLLAAAGGWDSLAAELATTAEAYGSVLSGLAALHWRGP 60 DFALLPPEVNSARMYTGPG+ SL AA W LA EL + A Y SV+ L ++ W G Sbjct 2 FDFALLPPEVNSARMYTGPGSASLRTAAASWQLLAVELHSAASMYRSVVMDLTSMQWTGS 61 Query 61 AAESMAVTAAPYIGWLYTTAEKTQQTAIQARAAALAFEQAYAMTLPPPVVAANRIQLLAL 120 ++ SMA PY+ WL TAE+ TA QA AAA AFEQA+AMT+PPP++AANR +LLAL Sbjct 62 SSMSMAAAVIPYVDWLTVTAEQAGHTAAQATAAATAFEQAFAMTVPPPLIAANRAELLAL 121 Query 121 IATNFFGQNTAAIAATEAQYAEMWAQDAAAMYGYATASAAAALLTPFSPPRQTTNPAGLT 180 IATNFFGQNTAAIA TEAQY +MWAQDA AM Y ASAAA LTPF+ P+ TNPAG + Sbjct 122 IATNFFGQNTAAIATTEAQYMQMWAQDATAMDDYTVASAAAWKLTPFASPQPDTNPAGRS 181 Query 181 AQAAAVSQAT--------DPLSLLIETVTQALQA-------------------LTIPSFI 213 AQ AAV++A + + L++ + AL A L +P + Sbjct 182 AQHAAVTRAITKAPDNKGNWIGNLLKDIGAALTAVGLPEVGVPLYALGEFVNTLKLPKIL 241 Query 214 PEDFTFLDAIFAGYATVGVTQDVESFVAGTIGAESNLGLLN---------VGDENPAEVT 264 +DFT LDA+FA Y+T+G V G I E +LGL++ V PA + Sbjct 242 KDDFTALDALFAWYSTMGSVTGVSGMTNGIINTEKSLGLISGVTQPVAETVPKVAPALLA 301 Query 265 PGDFGIGELVSATSPGGGVSASGAGGAASVGNTVLASVGRANSIGQLSVPPSWAAP---- 320 P + L AT GGV +G V A+ A SIGQLSVPPSWA P Sbjct 302 PLNSIAKSLSGATMRAGGV----------LGGQVSAAARSAGSIGQLSVPPSWATPQAAV 351 Query 321 STRPVSALSPAGLTTLPGTDVAEHGMPGVPGVPVAAGRASGVLPRYGVRLTVMAHPPAAG 380 + + A +P LTTLP +D A MPG+PG+P AA +GV+PRYG+R+TVM+ P + G Sbjct 352 AAKTFQAATP--LTTLPTSDAAPAAMPGLPGMPSAATGRAGVVPRYGLRMTVMSRPLSGG 409 >gi|183983432|ref|YP_001851723.1| PPE family protein, PPE61_1 [Mycobacterium marinum M] gi|183176758|gb|ACC41868.1| PPE family protein, PPE61_1 [Mycobacterium marinum M] Length=391 Score = 278 bits (711), Expect = 1e-72, Method: Compositional matrix adjust. Identities = 181/406 (45%), Positives = 243/406 (60%), Gaps = 41/406 (10%) Query 1 MDFALLPPEVNSARMYTGPGAGSLLAAAGGWDSLAAELATTAEAYGSVLSGLAALHWRGP 60 M F +LPPE+NS RMY+GPG+ SL AA+ W+S++ L + AE+Y ++++ L + W GP Sbjct 1 MSFMMLPPEINSTRMYSGPGSASLRAASASWNSVSVGLHSAAESYRAMIADLTSFQWLGP 60 Query 61 AAESMAVTAAPYIGWLYTTAEKTQQTAIQARAAALAFEQAYAMTLPPPVVAANRIQLLAL 120 ++ +M + PY+GWL TA + +A+QA AAA A+EQA+AMT+PPP +A NR +L AL Sbjct 61 SSAAMVASVLPYVGWLEATAVQAGHSAMQASAAAAAYEQAFAMTVPPPAIAVNRAELAAL 120 Query 121 IATNFFGQNTAAIAATEAQYAEMWAQDAAAMYGYATASAAAALLTPFSPPRQTTNPAGLT 180 IATNFFGQNTAAIAA EA+YAEMWA DA AM Y++ SAAA LTPF+ P QTTNPAGL Sbjct 121 IATNFFGQNTAAIAANEAEYAEMWATDATAMTSYSSTSAAARALTPFTSPHQTTNPAGLG 180 Query 181 AQAAAVSQAT--------DPLSLLIETVTQAL------------------QALTIPSFIP 214 AQ+AAV+ +T + L LI+ + AL + PSF+ Sbjct 181 AQSAAVANSTANVAADSGNWLGNLIDAIGVALLPIAPELSAILIPLGELINMIPFPSFLA 240 Query 215 EDFTFLDAIFAGYATVGVTQDVESFVAGTIGAESNLGLLNVGDENPAEVTPGDFGIGELV 274 +DFT LD + A YAT+G Q+++S +G IG + LGL+ A+ +G Sbjct 241 DDFTILDGLLAFYATIGSMQNIQSMASGIIGTDDTLGLIPHAAAAAADAPNALAALGG-- 298 Query 275 SATSPGGGVSASGAGGAASVGNTVLASVGRANSIGQLSVPPSWAAPSTRPVSALSPAGLT 334 PG G A +G + A + N IGQ+SVPPSW P + AL LT Sbjct 299 ---EPGLG---------AELG-PIAAELTSGNRIGQMSVPPSWTEPKVTTIKALQATPLT 345 Query 335 TLPGTDVAEHGMPGVPGVPVAAGRASGVLPRYGVRLTVMAHPPAAG 380 TLP +V G+PG+PG+ + GV PRYGVRLTVM P + G Sbjct 346 TLPTDEVPASGIPGMPGMAMTGTGRGGVAPRYGVRLTVMTRPFSGG 391 >gi|183983433|ref|YP_001851724.1| PPE family protein, PPE61 [Mycobacterium marinum M] gi|183176759|gb|ACC41869.1| PPE family protein, PPE61 [Mycobacterium marinum M] Length=391 Score = 276 bits (707), Expect = 3e-72, Method: Compositional matrix adjust. Identities = 182/406 (45%), Positives = 243/406 (60%), Gaps = 41/406 (10%) Query 1 MDFALLPPEVNSARMYTGPGAGSLLAAAGGWDSLAAELATTAEAYGSVLSGLAALHWRGP 60 M F +LPPE+NS RMYTGPG+ SL AA+ W+S++ L + AE+Y ++++ L + W GP Sbjct 1 MSFMMLPPEINSTRMYTGPGSASLRAASASWNSVSVGLHSAAESYRAMIADLTSFQWLGP 60 Query 61 AAESMAVTAAPYIGWLYTTAEKTQQTAIQARAAALAFEQAYAMTLPPPVVAANRIQLLAL 120 ++ +M + PY+GWL TA + +A+QA AAA A+EQA+AMT+PPP +A NR +L AL Sbjct 61 SSAAMIASVLPYVGWLEATAVQAGHSAMQASAAAAAYEQAFAMTVPPPAIAVNRAELAAL 120 Query 121 IATNFFGQNTAAIAATEAQYAEMWAQDAAAMYGYATASAAAALLTPFSPPRQTTNPAGLT 180 IATNFFGQNTAAIAA EA+YAEMWA DA AM Y++ SAAA LTPF+ P+QTTNPAGL Sbjct 121 IATNFFGQNTAAIAANEAEYAEMWATDATAMTSYSSTSAAARALTPFTSPQQTTNPAGLG 180 Query 181 AQAAAVSQAT--------DPLSLLIETVTQAL------------------QALTIPSFIP 214 AQ+AAV+ +T + L LI+ + AL + PSF Sbjct 181 AQSAAVANSTANVAADSGNWLGNLIDAIGVALLPIAPELSAILIPLGELINMIPFPSFFA 240 Query 215 EDFTFLDAIFAGYATVGVTQDVESFVAGTIGAESNLGLLNVGDENPAEVTPGDFGIGELV 274 +DFT LD + A YAT+G ++++S +G IG E+ LGL+ A + Sbjct 241 DDFTILDGLLAFYATIGSIKNIQSMGSGIIGTENTLGLIPHAAAATAAAPNALAAL---- 296 Query 275 SATSPGGGVSASGAGGAASVGNTVLASVGRANSIGQLSVPPSWAAPSTRPVSALSPAGLT 334 GG A G A +G + A + N IGQ+SVPPSW P + AL LT Sbjct 297 ------GGEPALG----AELG-PIAAELTSGNRIGQMSVPPSWTEPKVTTIKALQATPLT 345 Query 335 TLPGTDVAEHGMPGVPGVPVAAGRASGVLPRYGVRLTVMAHPPAAG 380 TLP +V G+PG+PG+ + GV PRYGVRLTVM P + G Sbjct 346 TLPTDEVPASGIPGIPGMAMTGTGRGGVTPRYGVRLTVMPRPFSGG 391 >gi|118466535|ref|YP_883168.1| PPE family protein [Mycobacterium avium 104] gi|118167822|gb|ABK68719.1| PPE family protein [Mycobacterium avium 104] Length=362 Score = 267 bits (682), Expect = 2e-69, Method: Compositional matrix adjust. Identities = 202/384 (53%), Positives = 243/384 (64%), Gaps = 26/384 (6%) Query 1 MDFALLPPEVNSARMYTGPGAGSLLAAAGGWDSLAAELATTAEAYGSVLSGLAALHWRGP 60 MDF LPPEVNSARMY GPG+GSLLAAAG WDSLAAEL+ TA Y SVL+GL L+W GP Sbjct 1 MDFGFLPPEVNSARMYAGPGSGSLLAAAGSWDSLAAELSITAAVYESVLAGLTGLYWHGP 60 Query 61 AAESMAVTAAPYIGWLYTTAEKTQQTAIQARAAALAFEQAYAMTLPPPVVAANRIQLLAL 120 A+ +MA AAPY+GWL+TTAE+ QQTA QARAAA A+E A+AMT+PP VAANR QL AL Sbjct 61 ASRAMAAGAAPYVGWLHTTAERAQQTATQARAAAAAYELAHAMTVPPAAVAANRTQLAAL 120 Query 121 IATNFFGQNTAAIAATEAQYAEMWAQDAAAMYGYATASAAAALLTPFSPPRQTTNPAGLT 180 +ATNFFGQNTAAIAATEAQYAE WAQDAAAMY Y+ +SAAAA +PF+ PR+TT+P G+T Sbjct 121 VATNFFGQNTAAIAATEAQYAEYWAQDAAAMYAYSASSAAAAQFSPFASPRRTTDPGGVT 180 Query 181 AQAAAVSQATDPLSLLIETVTQALQALTIPSFIPEDFTFLDAIFAGYATVGVTQDVESFV 240 AQ AA A + S ++ TQ + S IP DF LD I T E Sbjct 181 AQQAA-VAAAETGSTGTDSGTQVIPPTAGASEIPLDFRILDTILGAQTTFRSIFTTEGIP 239 Query 241 AGTIGAESNLGLLNVGDENPAEVTPGDFGIGELVSATSPGGGVSASGAGGAASVGNTVLA 300 AG I A+ NLG+L PA + +P S +G G + A Sbjct 240 AGIIQADKNLGILPNLATIPAAL------------PRTPALSASPTGLG-------RIDA 280 Query 301 SVGRANSIGQLSVPPSWAAPSTRPVSALSPAGLTTLPGTD----VAEHGMPGVPGVPVAA 356 + RA IG +SVP W A + PV+A G + D V G+PG+PG + Sbjct 281 VLARAARIGPMSVPAGWTAATGNPVAAAPVTGWSEPSAADARPGVTAPGLPGIPGATLR- 339 Query 357 GRASGVLPRYGVRLTVMAHPPAAG 380 RA+ V+PRYGVR+TVMA PPAAG Sbjct 340 -RAALVVPRYGVRITVMARPPAAG 362 >gi|41409283|ref|NP_962119.1| hypothetical protein MAP3185 [Mycobacterium avium subsp. paratuberculosis K-10] gi|41398103|gb|AAS05733.1| hypothetical protein MAP_3185 [Mycobacterium avium subsp. paratuberculosis K-10] gi|336459363|gb|EGO38306.1| PPE family protein [Mycobacterium avium subsp. paratuberculosis S397] Length=362 Score = 265 bits (678), Expect = 8e-69, Method: Compositional matrix adjust. Identities = 205/390 (53%), Positives = 242/390 (63%), Gaps = 38/390 (9%) Query 1 MDFALLPPEVNSARMYTGPGAGSLLAAAGGWDSLAAELATTAEAYGSVLSGLAALHWRGP 60 MDF LPPEVNSARMY GPG+GSLLAAAG WDSLAAEL+ TA Y SVL+GL L+W GP Sbjct 1 MDFGFLPPEVNSARMYAGPGSGSLLAAAGSWDSLAAELSITAAVYESVLAGLTGLYWHGP 60 Query 61 AAESMAVTAAPYIGWLYTTAEKTQQTAIQARAAALAFEQAYAMTLPPPVVAANRIQLLAL 120 A+ +MA AAPY+GWL+TTAE+ QQTA QARAAA A+E A+AMT+PP VAANR QL AL Sbjct 61 ASRAMAAGAAPYVGWLHTTAERAQQTATQARAAAAAYELAHAMTVPPAAVAANRTQLAAL 120 Query 121 IATNFFGQNTAAIAATEAQYAEMWAQDAAAMYGYATASAAAALLTPFSPPRQTTNPAGLT 180 +ATNFFGQNTAAIAATEAQYAE WAQDAAAMY Y+ +SAAAA +PF PR+TT+P G+T Sbjct 121 VATNFFGQNTAAIAATEAQYAEYWAQDAAAMYAYSASSAAAAQFSPFPSPRRTTDPGGVT 180 Query 181 AQAAAV------SQATDPLSLLIETVTQALQALTIPSFIPEDFTFLDAIFAGYATVGVTQ 234 AQ AAV S TD + +I A S IP DF LD I T Sbjct 181 AQQAAVAAAETGSTGTDSGAQVIPPTAGA-------SEIPLDFRILDTILGAQTTFRSIF 233 Query 235 DVESFVAGTIGAESNLGLLNVGDENPAEVTPGDFGIGELVSATSPGGGVSASGAGGAASV 294 E AG I A+ NLG+L PA + +P S SG G Sbjct 234 TTEGIPAGIIQADKNLGILPNLATVPAAL------------PRTPALSASPSGLG----- 276 Query 295 GNTVLASVGRANSIGQLSVPPSWAAPSTRPVSALSPAGLTTLPGTD----VAEHGMPGVP 350 + A + RA IG +SVP W A + PV+A G + D V G+PG+P Sbjct 277 --RIDAVLARAARIGPMSVPAGWTAATGNPVAAAPVTGWSEPSAADARPGVTAPGLPGIP 334 Query 351 GVPVAAGRASGVLPRYGVRLTVMAHPPAAG 380 G + RA+ V+PRYGVR+TVMA PPAAG Sbjct 335 GATLR--RAALVVPRYGVRITVMARPPAAG 362 >gi|212596159|gb|ACJ35556.1| PPE33 [Mycobacterium avium subsp. avium] Length=362 Score = 263 bits (672), Expect = 3e-68, Method: Compositional matrix adjust. Identities = 201/384 (53%), Positives = 241/384 (63%), Gaps = 26/384 (6%) Query 1 MDFALLPPEVNSARMYTGPGAGSLLAAAGGWDSLAAELATTAEAYGSVLSGLAALHWRGP 60 MDF LPPEVNSARMY GPG+GSLLAAAG WDSLAAEL+ TA Y SVL GL L+W GP Sbjct 1 MDFGFLPPEVNSARMYAGPGSGSLLAAAGSWDSLAAELSITAAVYESVLGGLTGLYWHGP 60 Query 61 AAESMAVTAAPYIGWLYTTAEKTQQTAIQARAAALAFEQAYAMTLPPPVVAANRIQLLAL 120 A+ +MA AAPY+GWL+TTAE+ QQTA QARAAA A+E A+AMT+PP VAANR QL AL Sbjct 61 ASRAMAAGAAPYVGWLHTTAERAQQTATQARAAAAAYELAHAMTVPPAAVAANRTQLAAL 120 Query 121 IATNFFGQNTAAIAATEAQYAEMWAQDAAAMYGYATASAAAALLTPFSPPRQTTNPAGLT 180 +ATNFFGQNTAAIAATEAQYAE WAQDAAAMY Y+ +SAAAA +PF+ PR+TT+P G+T Sbjct 121 VATNFFGQNTAAIAATEAQYAEYWAQDAAAMYAYSASSAAAAQFSPFASPRRTTDPGGVT 180 Query 181 AQAAAVSQATDPLSLLIETVTQALQALTIPSFIPEDFTFLDAIFAGYATVGVTQDVESFV 240 AQ AA A + S ++ Q + S IP DF LD I T E Sbjct 181 AQQAA-VAAAETGSTGTDSGAQVIPPTAGGSEIPLDFRILDTILGAQTTFRSIFTTEGIP 239 Query 241 AGTIGAESNLGLLNVGDENPAEVTPGDFGIGELVSATSPGGGVSASGAGGAASVGNTVLA 300 AG I A+ NLG+L PA + +P S +G G + A Sbjct 240 AGIIQADENLGILPNLATVPAAL------------PRTPALSASPTGLG-------RIDA 280 Query 301 SVGRANSIGQLSVPPSWAAPSTRPVSALSPAGLTTLPGTD----VAEHGMPGVPGVPVAA 356 + RA IG +SVP W A + PV+A G + D V G+PG+PG + Sbjct 281 VLARAARIGPMSVPAGWTAATGNPVAAAPVTGWSEPSAADARPGVTAPGLPGIPGATLR- 339 Query 357 GRASGVLPRYGVRLTVMAHPPAAG 380 RA+ V+PRYGVR+TVMA PPAAG Sbjct 340 -RAALVVPRYGVRITVMARPPAAG 362 >gi|240173322|ref|ZP_04751980.1| PPE family protein [Mycobacterium kansasii ATCC 12478] Length=402 Score = 259 bits (661), Expect = 7e-67, Method: Compositional matrix adjust. Identities = 188/405 (47%), Positives = 236/405 (59%), Gaps = 32/405 (7%) Query 2 DFALLPPEVNSARMYTGPGAGSLLAAAGGWDSLAAELATTAEAYGSVLSGLAALHWRGPA 61 DFA LPPEV S RMY+GPG+GSL AAA GW L+AEL +A+ Y SV+S L A HW GP+ Sbjct 4 DFAFLPPEVISTRMYSGPGSGSLQAAAEGWQQLSAELHASAQTYRSVVSDLIAWHWVGPS 63 Query 62 AESMAVTAAPYIGWLYTTAEKTQQTAIQARAAALAFEQAYAMTLPPPVVAANRIQLLALI 121 + +MA A Y WL TA +T QTA QA AA AF++A+AMT+PP +V ANR QLL LI Sbjct 64 SAAMAAAATSYAEWLEATAIQTGQTARQAATAASAFDEAFAMTVPPSIVFANREQLLLLI 123 Query 122 ATNFFGQNTAAIAATEAQYAEMWAQDAAAMYGYATASAAAALLTPFSPPRQTTNPAGL-- 179 ATNFFGQNT+AIAA E YAEMW +++ M Y+ SAAA LTPF+ P+Q TNPAGL Sbjct 124 ATNFFGQNTSAIAALELAYAEMWVTNSSVMQDYSVTSAAATKLTPFASPQQATNPAGLPG 183 Query 180 ------TAQAAAVSQATDPLSLLIETVTQAL------------------QALTIPSFIPE 215 A A A + + L L+E + AL A+ PS + + Sbjct 184 QAAAVAQATAGAAADGGNWLGNLLEQIGMALLPFAPELTPFFLEAGELINAIPFPSIVAD 243 Query 216 DFTFLDAIFAGYATVGVTQDVESFVAGTIGAESNLGLLNVGDENPAEVTPGDFGIGELVS 275 DFTFLD + A YATV ++ S G IGAE NLG+L AEV P + + LV+ Sbjct 244 DFTFLDGVMAWYATVSSINNISSLGTGIIGAEKNLGILPSLAAPAAEVVPSE--LAPLVN 301 Query 276 ATSPGGGVSASGAGGAASVGNTVLASVGRANSIGQLSVPPSWAAPSTRPVSALSPAGLTT 335 + V+ + A G +G A G A SIG +SVPP+W AP+ V LTT Sbjct 302 SVK---NVADAVAKGGPGIGEVTAAFRG-AGSIGPMSVPPTWTAPAVTTVKTFQGTPLTT 357 Query 336 LPGTDVAEHGMPGVPGVPVAAGRASGVLPRYGVRLTVMAHPPAAG 380 LP D GMPG+PG+ A R GV+PRYG+ VM P + G Sbjct 358 LPAGDAGGAGMPGMPGIAPAGTRRGGVVPRYGLTPRVMTRPLSGG 402 >gi|118618170|ref|YP_906502.1| PPE family protein [Mycobacterium ulcerans Agy99] gi|118570280|gb|ABL05031.1| PPE family protein [Mycobacterium ulcerans Agy99] Length=377 Score = 252 bits (643), Expect = 8e-65, Method: Compositional matrix adjust. Identities = 173/392 (45%), Positives = 231/392 (59%), Gaps = 41/392 (10%) Query 15 MYTGPGAGSLLAAAGGWDSLAAELATTAEAYGSVLSGLAALHWRGPAAESMAVTAAPYIG 74 MYTGPG+ SL AA+ W+ ++ L + AE+Y ++++ L + W GP++ +M + PY+G Sbjct 1 MYTGPGSASLRAASASWNGVSVGLHSAAESYRAMIADLTSFQWLGPSSAAMVASVLPYVG 60 Query 75 WLYTTAEKTQQTAIQARAAALAFEQAYAMTLPPPVVAANRIQLLALIATNFFGQNTAAIA 134 WL TA + +A+QA AAA A+EQA+AMT+PPP +A NR +L ALIAT+FFGQNTAAIA Sbjct 61 WLEATAVQAGHSAMQASAAAAAYEQAFAMTVPPPAIAVNRAELAALIATDFFGQNTAAIA 120 Query 135 ATEAQYAEMWAQDAAAMYGYATASAAAALLTPFSPPRQTTNPAGLTAQAAAVSQAT---- 190 A EA+YAEMWA DA AM Y++ SAAA LTPFS P QTTNPAGL AQ+AAV+ +T Sbjct 121 ANEAEYAEMWATDATAMTSYSSTSAAARALTPFSSPHQTTNPAGLGAQSAAVAHSTANVA 180 Query 191 ----DPLSLLIETVTQAL------------------QALTIPSFIPEDFTFLDAIFAGYA 228 + L LI+ + AL + PSF+ +DFT LD + A YA Sbjct 181 ADSGNWLGNLIDAIGVALLPIAPELSAILIPLGELINMIPFPSFLADDFTVLDGLLAFYA 240 Query 229 TVGVTQDVESFVAGTIGAESNLGLLNVGDENPAEVTPGDFGIGELVSATSPGGGVSASGA 288 T+G Q+++S +G IG + LGL+ P L + GG A G Sbjct 241 TIGSMQNIQSMGSGIIGTDDTLGLI------PHAAAATADAPNALAAL----GGEPALG- 289 Query 289 GGAASVGNTVLASVGRANSIGQLSVPPSWAAPSTRPVSALSPAGLTTLPGTDVAEHGMPG 348 A +G + A + N IGQ+SVPPSW P + AL LTTLP +V G+PG Sbjct 290 ---AELG-PIAAELTSGNRIGQMSVPPSWTDPKVTTIKALQATPLTTLPTDEVPASGIPG 345 Query 349 VPGVPVAAGRASGVLPRYGVRLTVMAHPPAAG 380 +PG+ + GV PRYGVRLTVM P + G Sbjct 346 MPGMAMTGTGRGGVAPRYGVRLTVMPRPFSGG 377 >gi|342861033|ref|ZP_08717682.1| PPE family protein [Mycobacterium colombiense CECT 3035] gi|342131477|gb|EGT84747.1| PPE family protein [Mycobacterium colombiense CECT 3035] Length=376 Score = 249 bits (635), Expect = 7e-64, Method: Compositional matrix adjust. Identities = 186/389 (48%), Positives = 236/389 (61%), Gaps = 36/389 (9%) Query 15 MYTGPGAGSLLAAAGGWDSLAAELATTAEAYGSVLSGLAALHWRGPAAESMAVTAAPYIG 74 MYTGPG SLLAAAG WD+L+AELA+TAE+Y SVL GL L WRGPAAESMA +AA Y+G Sbjct 1 MYTGPGLASLLAAAGSWDALSAELASTAESYESVLVGLG-LQWRGPAAESMAYSAARYMG 59 Query 75 WLYTTAEKTQQTAIQARAAALAFEQAYAMTLPPPVVAANRIQLLALIATNFFGQNTAAIA 134 WL TAE+T+QTA+QAR AA A+EQAY+MT+PPPV+AANR L +L+ATN GQNTAAIA Sbjct 60 WLEATAEQTKQTAMQARTAAAAYEQAYSMTVPPPVIAANRTLLASLVATNIVGQNTAAIA 119 Query 135 ATEAQYAEMWAQDAAAMYGY-ATASAAAALLTPFSPPRQTTNPAGLTAQAAAVSQATDP- 192 TEAQY++ WAQDAAAM GY A+++ A A L F+ ++T +G++AQ AAV+ A Sbjct 120 DTEAQYSDFWAQDAAAMAGYSASSTVATAQLPRFATANKSTTESGVSAQNAAVATANTNA 179 Query 193 --LSLLIETVTQALQALTIPSFIPEDFTFLDAIFAGYAT-------------VGVT--QD 235 + +T + + T P P D +LDA T +G T + Sbjct 180 GATKVAAQTFSPLDTSPTGPGSTPGDIYYLDASTTSSGTNAFRVLDAIQGTSLGFTAPYN 239 Query 236 VESFVAGTIGAESNLGLLNVGDENPAEVTPGDFGIGELVSATSPGGGVSASGAGGAASVG 295 +E FV+G IGAE+NLG+L G A + G Sbjct 240 MEQFVSGIIGAENNLGIL------------AKPGAAAANLAPAIAAPALRGATAGLGGGL 287 Query 296 NTVLASVGRANSIGQLSVPPSWAAPSTRPVSALSPAGLTTLPGTD----VAEHGMPGVPG 351 V A++ A +IG +SVP SWAAP++ +S L PAG TT+PGT+ G PG+PG Sbjct 288 GNVTATLSHAGTIGPMSVPASWAAPTSTHISPLEPAGFTTIPGTEEPVASGYPGYPGLPG 347 Query 352 VPVAAGRASGVLPRYGVRLTVMAHPPAAG 380 A +GV PRYGVRLTVM PPAAG Sbjct 348 GGAARSAGAGVPPRYGVRLTVMPRPPAAG 376 >gi|212596661|gb|ACJ35596.1| PPE32 [Mycobacterium intracellulare ATCC 13950] Length=391 Score = 237 bits (604), Expect = 3e-60, Method: Compositional matrix adjust. Identities = 194/408 (48%), Positives = 239/408 (59%), Gaps = 45/408 (11%) Query 1 MDFALLPPEVNSARMYTGPGAGSLLAAAGGWDSLAAELATTAEAYGSVLSGLAALHWRGP 60 MD+A +PPE+NSARMYTGPG GSLLAAAG WD+L+AEL++ AE Y S LSGL L WRGP Sbjct 1 MDWAFVPPEINSARMYTGPGMGSLLAAAGSWDALSAELSSAAEGYESALSGLD-LQWRGP 59 Query 61 AAESMAVTAAPYIGWLYTTAEKTQQTAIQARAAALAFEQAYAMTLPPPVVAANRIQLLAL 120 AA++MA A Y WL TAE+T+QTA+QAR AA A+EQAYAMT+PPPV+ ANR L AL Sbjct 60 AAQAMAFAAIRYAEWLQVTAEQTRQTAMQARTAAAAYEQAYAMTVPPPVITANRTLLAAL 119 Query 121 IATNFFGQNTAAIAATEAQYAEMWAQDAAAMYGYATASAAAALLTPFSPPRQTTNPAGLT 180 +A+N GQNTAAIA TEAQYA+ WAQDAAAM Y+ +SAAA L F+P +TN +G++ Sbjct 120 VASNIVGQNTAAIADTEAQYADYWAQDAAAMSAYSVSSAAATQLPRFAPATNSTNESGVS 179 Query 181 AQA-------------AAVSQATDPLSLL-----------IETVTQALQALTIPSFIPED 216 AQ AV+Q+ PLS I ++ A F Sbjct 180 AQKAAVTAANSNAAANKAVTQSYSPLSTQQTGDTYNYYGDIYDLSDTTAAAGGKPF---- 235 Query 217 FTFLDAIFAGYATVGVTQDVESFVAGTIGAESNLGLLNVGDENPAEVTPGDFGIGELVSA 276 F LDAI ++E FV+G IGAE+NLG+L A Sbjct 236 FAALDAIQGTGVGFSAPYNMEQFVSGIIGAENNLGILAKPLAA------------APALA 283 Query 277 TSPGGGVSASGAGGAASVGNTVLASVGRANSIGQLSVPPSWAAPSTRPVSALSPAGLTTL 336 + S GG + V A++ A SIG +SVP SWAAP++ +S L PAG TTL Sbjct 284 APALSSTTTSLGGGLGAGLGNVTATLSHAGSIGPMSVPASWAAPTSTHISPLEPAGFTTL 343 Query 337 PGTD--VAEHGMPGVPGVPVAAGRA--SGVLPRYGVRLTVMAHPPAAG 380 PGT+ VA A R+ +GV PRYGVRLTVM PPAAG Sbjct 344 PGTEEPVASGYPGYPGMPGGGASRSVGAGVPPRYGVRLTVMPRPPAAG 391 >gi|118463069|ref|YP_883167.1| PPE family protein [Mycobacterium avium 104] gi|118164356|gb|ABK65253.1| ppe family protein [Mycobacterium avium 104] Length=391 Score = 230 bits (586), Expect = 3e-58, Method: Compositional matrix adjust. Identities = 196/402 (49%), Positives = 246/402 (62%), Gaps = 33/402 (8%) Query 1 MDFALLPPEVNSARMYTGPGAGSLLAAAGGWDSLAAELATTAEAYGSVLSGLAALHWRGP 60 MD+A LPPE+NSARMYTG GA SLLAAAG WD+L+AEL TA+ Y SVLSGL L W GP Sbjct 1 MDWAFLPPEINSARMYTGAGAASLLAAAGSWDALSAELTATADGYESVLSGLG-LQWHGP 59 Query 61 AAESMAVTAAPYIGWLYTTAEKTQQTAIQARAAALAFEQAYAMTLPPPVVAANRIQLLAL 120 AA++MA AA Y+ WL TAE+T+QTA+QAR AA A+EQAYAMT+PPPV+AANR L +L Sbjct 60 AADAMAFAAARYLTWLRATAEQTKQTAMQARTAAAAYEQAYAMTVPPPVIAANRTLLASL 119 Query 121 IATNFFGQNTAAIAATEAQYAEMWAQDAAAMYGYATASAAAALLTPFSPPRQTTNPAGLT 180 +ATN GQNTAAIA TEAQYA+ WAQD AAM GY+ +S AA L F+ +TN +G+T Sbjct 120 VATNIMGQNTAAIADTEAQYADFWAQDTAAMAGYSASSTAATQLPRFASANNSTNESGVT 179 Query 181 AQAAAVSQATDPLSLLIETVTQALQAL-------TIPSFIPE----------DFTFLDAI 223 AQ AAVS A + + VTQ+ L TI ++ + F LD I Sbjct 180 AQNAAVSAANA-NAAANKAVTQSFSPLADNPPGTTINNYYVDASSTSAANSNAFRVLDVI 238 Query 224 FAGYATVGVTQDVESFVAGTIGAESNLGLLNVGDENPAEVTPGDFGIGELVSATSPGG-G 282 ++E FV+G IGAE+NLG+L PG + +P G Sbjct 239 QGTGLGFSAPYNMEQFVSGIIGAENNLGML---------AKPGAAAANIAPALAAPALRG 289 Query 283 VSASGAGGAASVGNTVLASVGRANSIGQLSVPPSWAAPSTRPVSALSPAGLTTLPGTD-- 340 +A GG V A++ A +IG +SVP +W+AP++ VS L+PAG TTLPGT+ Sbjct 290 ATAGLGGGLGGGLGNVTATLSHAGTIGPMSVPATWSAPTSTHVSPLAPAGFTTLPGTEEP 349 Query 341 VAEHGMPGVPGVPVAAGRAS--GVLPRYGVRLTVMAHPPAAG 380 +A A R++ GV PRYGVRLTVM PPAAG Sbjct 350 MASGYPGYPGMPGGGAARSAGVGVPPRYGVRLTVMPRPPAAG 391 >gi|342861034|ref|ZP_08717683.1| PPE family protein [Mycobacterium colombiense CECT 3035] gi|342131478|gb|EGT84748.1| PPE family protein [Mycobacterium colombiense CECT 3035] Length=355 Score = 228 bits (582), Expect = 1e-57, Method: Compositional matrix adjust. Identities = 191/374 (52%), Positives = 228/374 (61%), Gaps = 27/374 (7%) Query 15 MYTGPGAGSLLAAAGGWDSLAAELATTAEAYGSVLSGLAALHWRGPAAESMAVTAAPYIG 74 MY GPG+GSLLAAAG WDSL+AEL TA Y SVLSGL LHW GPAA +MA +AAPY+ Sbjct 1 MYAGPGSGSLLAAAGSWDSLSAELGVTAAVYESVLSGLTGLHWHGPAARAMAASAAPYVA 60 Query 75 WLYTTAEKTQQTAIQARAAALAFEQAYAMTLPPPVVAANRIQLLALIATNFFGQNTAAIA 134 WLY+TAE QQTA+QARAAA A+E A+AMT+PPPVVAANR QL L+ATNFFGQNTAAIA Sbjct 61 WLYSTAELAQQTAMQARAAAAAYELAHAMTVPPPVVAANRTQLATLVATNFFGQNTAAIA 120 Query 135 ATEAQYAEMWAQDAAAMYGYATASAAAALLTPFSPPRQTTNPAGLTAQAAAVSQATDPLS 194 ATEA+YAE WAQDAAAMYGY+ +S AA +PF+ PRQTT G+ Q AV QA S Sbjct 121 ATEAEYAEYWAQDAAAMYGYSASSTAAVQFSPFASPRQTTTTNGVATQQDAVVQAAANTS 180 Query 195 LLIETVTQALQALTIP---SFIPEDFTFLDAIFAGYATVGVTQDVESFVAGTIGAESNLG 251 + A + P S IP DF LD I A T E AG I A+ LG Sbjct 181 SSGVQSGSQVVANSSPPGTSEIPLDFRILDTIQAAQFTFRSIFTAEGTPAGIIQADKTLG 240 Query 252 LLNVGDENPAEVTPGDFGIGELVSATSPGGGVSASGAGGAASVGNTVLASVGRANSIGQL 311 +L +G L +A +S G + +GN V A + RA IG + Sbjct 241 ILP--------------NLGALPAALPKAPALS----GATSGMGN-VDAVLARAARIGPM 281 Query 312 SVPPSWAAPSTRPVSALSPAGLTTLPGTD-VAEHGMPGVPGVPVAAG----RASGVLPRY 366 SVP W + + V+AL GL+ L T+ VA G PG+P G RA+ V+PRY Sbjct 282 SVPAGWTSATGNQVAALPGGGLSDLTATEAVARAGTSATPGIPALPGGTVRRAALVVPRY 341 Query 367 GVRLTVMAHPPAAG 380 G R+TVMA P AAG Sbjct 342 GRRITVMARPFAAG 355 >gi|183982688|ref|YP_001850979.1| PPE family protein, PPE31_1 [Mycobacterium marinum M] gi|183176014|gb|ACC41124.1| PPE family protein, PPE31_1 [Mycobacterium marinum M] Length=422 Score = 224 bits (570), Expect = 3e-56, Method: Compositional matrix adjust. Identities = 181/422 (43%), Positives = 231/422 (55%), Gaps = 42/422 (9%) Query 1 MDFALLPPEVNSARMYTGPGAGSLLAAAGGWDSLAAELATTAEAYGSVLSGLAALHWRGP 60 MDFA LPPE+NS RMY+GPG+ +LAA WD LAAEL +TA AY +V++ L W GP Sbjct 1 MDFAALPPEINSIRMYSGPGSAPMLAAVTAWDGLAAELRSTAAAYETVIAVLTGDGWLGP 60 Query 61 AAESMAVTAAPYIGWLYTTAEKTQQTAIQARAAALAFEQAYAMTLPPPVVAANRIQLLAL 120 A+ESM PY+ W+ T + +QTA QA AAA AFE A+AMT+PP VAANR QL L Sbjct 61 ASESMEAAVFPYLAWMNITGMQAEQTARQAAAAAGAFEAAFAMTVPPAQVAANRTQLQTL 120 Query 121 IATNFFGQNTAAIAATEAQYAEMWAQDAAAMYGYATASAAAALLTPFSPPRQTTNPAGLT 180 +ATN GQNT AIAATEA Y EMWAQDAAAMYGYA SAAA+ LT F+ P QTT+P+GL Sbjct 121 VATNLLGQNTPAIAATEAAYGEMWAQDAAAMYGYAVGSAAASTLTQFTQPAQTTDPSGLA 180 Query 181 AQAAAVSQAT---------DPLSLLIETVTQALQALTIPS------------FIPEDFTF 219 +Q+AAV+QA L L+ V +LQ L P+ + F Sbjct 181 SQSAAVTQAVGSTVGNLTQTELPQLMSAVPASLQGLASPAAASPIDAIPGSGLLAALLNF 240 Query 220 LDAIFAG-YATVGVTQDVESFV-AGTIG----------AESNLGLLNVGDENPAEVTPGD 267 LD Y + V FV AG + A +++ + +G + A V P Sbjct 241 LDGNDGNPYGVFLNSSLVNGFVSAGYVSPAVVGPAIWAAMADINAVALGAQESAAVPPMG 300 Query 268 FGIGE--LVSATSPGG--GVSASGAGGAASVGN-TVLASVGRANSIGQLSVPPSWAAPST 322 G G + A SP + G AA++G + A + +A +G++SVP SW + Sbjct 301 SGEGNPSWIPAASPASPESLPVLGEETAATLGTGGISAGMNQAELVGRMSVPQSWGVATA 360 Query 323 RPVSALSPAGLTTLPGTDV---AEHGMPGVPGVPVAA-GRASGVLPRYGVRLTVMAHPPA 378 A + A T V A GMPG+PG+P G G PRYG R T+M PPA Sbjct 361 VANHAGAAAPGGGWTSTAVVPEAAVGMPGIPGMPAGIYGHNLGNAPRYGFRPTIMGRPPA 420 Query 379 AG 380 AG Sbjct 421 AG 422 >gi|240172861|ref|ZP_04751520.1| PPE family protein, PPE31 [Mycobacterium kansasii ATCC 12478] Length=401 Score = 219 bits (559), Expect = 4e-55, Method: Compositional matrix adjust. Identities = 191/418 (46%), Positives = 232/418 (56%), Gaps = 59/418 (14%) Query 1 MDFALLPPEVNSARMYTGPGAGSLLAAAGGWDSLAAELATTAEAYGSVLSGLAALHWRGP 60 +DFA+LPPE+NSARMY+GPG+G +LAAA W SLAAEL TA +Y SVL+ L W GP Sbjct 5 LDFAMLPPEINSARMYSGPGSGPMLAAASAWKSLAAELRATALSYHSVLAALTGEEWYGP 64 Query 61 AAESMAVTAAPYIGWLYTTAEKTQQTAIQARAAALAFEQAYAMTLPPPVVAANRIQLLAL 120 A+ SMA AAPY+ WL TTA + +QTA+QA AAA A+E A+ T+PPPV+AANR QL+AL Sbjct 65 ASASMAAAAAPYVAWLNTTAVQAEQTAVQAEAAAGAYEAAFGATVPPPVIAANRAQLMAL 124 Query 121 IATNFFGQNTAAIAATEAQYAEMWAQDAAAMYGYATASAAAALLTPFSPPRQTTNPAGLT 180 IATN GQNT AIAATEAQY EMWAQDA AMYGYA +SAAA L+PF P+Q TNP+GL Sbjct 125 IATNILGQNTPAIAATEAQYTEMWAQDAMAMYGYAGSSAAATQLSPFVEPQQATNPSGLA 184 Query 181 AQAAAVSQA--------TDPLSLLIETVTQALQALTIPSFIPEDFTFLDAIF-----AGY 227 AQAAAV++A + LS LI V ALQ L+ P ++L I+ +G Sbjct 185 AQAAAVTEASANSAGNQSSTLSGLISMVPSALQGLS----GPNSTSWLQVIWDLLTGSGP 240 Query 228 ATVGVTQDVESFVAGTIGAESNLGLLNVGDE----------------------NPAEVTP 265 A +V A ++ GL G A Sbjct 241 AWWQTLWNVWGPNANVWNTITSTGLFVPGSTFAPFMASVLAGAVAADAAQDASAAAAGVG 300 Query 266 GDFGIGELVSATSPGGGVSASGAGGAASVGNTVLASVGRANSIGQLSVPPSW--AAPSTR 323 G L S S G VSA G G A VG LSVPP+W AAP Sbjct 301 SGLAAGPLASTGSVGSAVSA-GLGNAGIVGK--------------LSVPPAWTAAAPLHS 345 Query 324 PV-SALSPAGLTTLPGTDVAEHGMPGVPGVPVAAGRASGVLPRYGVRLTVMAHPPAAG 380 P+ SAL + P A GMPG+P +A +P+YG R T +A PPAAG Sbjct 346 PLGSALGGTPMVAPPPAVAA--GMPGMPFGNMAGQPFGRAVPQYGFRPTFVARPPAAG 401 >gi|240169037|ref|ZP_04747696.1| PPE family protein [Mycobacterium kansasii ATCC 12478] Length=391 Score = 219 bits (559), Expect = 5e-55, Method: Compositional matrix adjust. Identities = 180/407 (45%), Positives = 223/407 (55%), Gaps = 43/407 (10%) Query 1 MDFALLPPEVNSARMYTGPGAGSLLAAAGGWDSLAAELATTAEAYGSVLSGLAALHWRGP 60 MDF LPPE+NSARMYTGPG+GSLLAAA WD +A +L A A SV+ GL WRG Sbjct 1 MDFGALPPEINSARMYTGPGSGSLLAAAQVWDGVAIDLYNAASAVQSVIWGLLVGPWRGT 60 Query 61 AAESMAVTAAPYIGWLYTTAEKTQQTAIQARAAALAFEQAYAMTLPPPVVAANRIQLLAL 120 +A M A+PY+ WL TTA + + TA Q R AA A+E A+A T+PP V+A NRIQLL L Sbjct 61 SAGLMVAAASPYVTWLGTTAAQAELTADQVRTAATAYEAAFATTVPPAVIAGNRIQLLTL 120 Query 121 IATNFFGQNTAAIAATEAQYAEMWAQDAAAMYGYA-TASAAAALLTPFSPPRQTTNPAGL 179 IA+N FGQNT AIA TEA Y EMWAQDAAAMYGYA +A+ AA LTPF + TN GL Sbjct 121 IASNLFGQNTPAIAVTEADYGEMWAQDAAAMYGYAGSAAVAAETLTPFDESPEITNAGGL 180 Query 180 TAQAAAVSQATDP--LSLLIETVTQALQALTIPSFIPEDFTFLDAIFAGYA-TVGVTQDV 236 QA AV +ATD + LI TV QALQ L P FT + ++ + + ++ Sbjct 181 VQQAGAVEEATDTAAANQLISTVPQALQQLAEPGQGTTPFTAVGELWKAISPHLSPISNI 240 Query 237 ESFVAGTIGA-ESNLGLLNVGDENPAEVTP------------GDFGIGELVSATSPGGGV 283 S + + S + + N + P G +G L G G+ Sbjct 241 VSMLNNHVSMLSSGMSMTNTASSLLKGMAPAAAQAVESAVESGARAMGSL------GSGL 294 Query 284 SASGAGGAASVGNTVLASVGRANSIGQLSVPPSWAAPSTRPV---SALSPAGLTTLPGTD 340 SG GG+ V A +GRA SIG LSVP WAA + V AL AG+ T Sbjct 295 GTSGIGGSG-----VAAGLGRALSIGSLSVPHGWAAANQTVVPAARALPLAGVAT----- 344 Query 341 VAEHG-MPGVPGVPVA----AGRASGV--LPRYGVRLTVMAHPPAAG 380 AE G P + G+P+ AG +GV + R R VM PAAG Sbjct 345 AAETGPAPMLGGLPLGQLANAGGGNGVSGVLRVTPRPYVMPRTPAAG 391 >gi|212596672|gb|ACJ35597.1| PPE33 [Mycobacterium intracellulare ATCC 13950] Length=390 Score = 218 bits (555), Expect = 1e-54, Method: Compositional matrix adjust. Identities = 147/253 (59%), Positives = 170/253 (68%), Gaps = 3/253 (1%) Query 1 MDFALLPPEVNSARMYTGPGAGSLLAAAGGWDSLAAELATTAEAYGSVLSGLAALHWRGP 60 MDF LPPEVNS RMY GPG+GSLLAAAG WDSLAAEL+ TA Y SVLSGL L W GP Sbjct 1 MDFGFLPPEVNSGRMYAGPGSGSLLAAAGSWDSLAAELSITAAVYESVLSGLTGLSWYGP 60 Query 61 AAESMAVTAAPYIGWLYTTAEKTQQTAIQARAAALAFEQAYAMTLPPPVVAANRIQLLAL 120 A+++MA +AAPY+GWL+ TAE+ QQT IQARAAA A+E A AMT+PPP VAANR QL L Sbjct 61 ASQAMAASAAPYVGWLHATAERAQQTGIQARAAAAAYELARAMTVPPPAVAANRTQLATL 120 Query 121 IATNFFGQNTAAIAATEAQYAEMWAQDAAAMYGYATASAAAALLTPFSPPRQTTNPAGLT 180 +ATNFFGQNTAAIAA EAQYAE WAQDA+AMY Y+ +SAA +PFS PR+ T G+T Sbjct 121 VATNFFGQNTAAIAANEAQYAEYWAQDASAMYSYSASSAATVQFSPFSAPREATTQDGVT 180 Query 181 AQAAAVSQATDPLSLLIETVTQALQALTIPSFIPEDFTFLDAIFAGYATVGVTQDVESFV 240 AQ AV+QAT + L A + LD I E F Sbjct 181 AQQDAVTQATANAANSNAGPGSQLFAFSRRDGFAR---ILDTIQGAQVAFRSIFTAEGFN 237 Query 241 AGTIGAESNLGLL 253 AG I A+ NLG+L Sbjct 238 AGIIQADKNLGIL 250 >gi|41409282|ref|NP_962118.1| hypothetical protein MAP3184 [Mycobacterium avium subsp. paratuberculosis K-10] gi|41398102|gb|AAS05732.1| hypothetical protein MAP_3184 [Mycobacterium avium subsp. paratuberculosis K-10] Length=391 Score = 218 bits (555), Expect = 1e-54, Method: Compositional matrix adjust. Identities = 193/401 (49%), Positives = 242/401 (61%), Gaps = 31/401 (7%) Query 1 MDFALLPPEVNSARMYTGPGAGSLLAAAGGWDSLAAELATTAEAYGSVLSGLAALHWRGP 60 MD+A LPPE+NSARMYTG GA SLLAAAG WD+L+AEL TA+ Y SVLSGL L W GP Sbjct 1 MDWAFLPPEINSARMYTGAGAASLLAAAGSWDALSAELTATADGYESVLSGLG-LQWHGP 59 Query 61 AAESMAVTAAPYIGWLYTTAEKTQQTAIQARAAALAFEQAYAMTLPPPVVAANRIQLLAL 120 AA++MA AA Y+ WL TAE+T+QTA+QAR AA A+EQAYAMT+PPPV+AANR L +L Sbjct 60 AADAMAFAAARYLTWLRATAEQTKQTAMQARTAAAAYEQAYAMTVPPPVIAANRTLLASL 119 Query 121 IATNFFGQNTAAIAATEAQYAEMWAQDAAAMYGYATASAAAALLTPFSPPRQTTNPAGL- 179 +ATN GQNTAAIA TEAQYA+ WAQD AAM GY+ +S AA L F+ +TN +G+ Sbjct 120 VATNIMGQNTAAIADTEAQYADFWAQDTAAMAGYSASSTAATQLPRFASANNSTNESGVT 179 Query 180 ------------TAQAAAVSQATDPLSLLIETVT---QALQALTIPSFIPEDFTFLDAIF 224 A AV+Q+ PL+ T + A + + F LD I Sbjct 180 AQNAAVTAANANAAANKAVTQSFSPLADNPPGTTINNYYVDASSTSAANSNAFRVLDVIQ 239 Query 225 AGYATVGVTQDVESFVAGTIGAESNLGLLNVGDENPAEVTPGDFGIGELVSATSPGG-GV 283 ++E FV+G IGAE+NLG+L PG + +P G Sbjct 240 GTGLGFSAPYNMEQFVSGIIGAENNLGML---------AKPGAAAANIAPALAAPALRGA 290 Query 284 SASGAGGAASVGNTVLASVGRANSIGQLSVPPSWAAPSTRPVSALSPAGLTTLPGTD--- 340 +A GG V A++ A +IG +SVP +W+AP++ VS L+PAG TTLPGT+ Sbjct 291 TAGLGGGLGGGLGNVTATLSHAGTIGPMSVPATWSAPTSTHVSPLAPAGFTTLPGTEEPM 350 Query 341 -VAEHGMPGVPGVPVAAGRASGVLPRYGVRLTVMAHPPAAG 380 G PG+PG A +GV PRYGVRLTVM PPAAG Sbjct 351 ASGYPGYPGMPGGGAARSAGAGVPPRYGVRLTVMPRPPAAG 391 >gi|254821012|ref|ZP_05226013.1| PPE family protein, PPE31 [Mycobacterium intracellulare ATCC 13950] gi|212596828|gb|ACJ35609.1| PPE48 [Mycobacterium intracellulare ATCC 13950] Length=389 Score = 211 bits (538), Expect = 1e-52, Method: Compositional matrix adjust. Identities = 173/405 (43%), Positives = 223/405 (56%), Gaps = 43/405 (10%) Query 1 MDFALLPPEVNSARMYTGPGAGSLLAAAGGWDSLAAELATTAEAYGSVLSGLAALHWRGP 60 +DFA LPPE+NSARMY GPG+G +L AA W+ LAAEL + A +YGS LS L + W GP Sbjct 3 VDFATLPPEINSARMYAGPGSGPMLVAASAWNGLAAELRSAALSYGSALSSLTSEEWHGP 62 Query 61 AAESMAVTAAPYIGWLYTTAEKTQQTAIQARAAALAFEQAYAMTLPPPVVAANRIQLLAL 120 A+ +M A PY+ W+ TTA + +Q A QA AAA A+E A+A T+PPP +AANR QL L Sbjct 63 ASAAMVAAATPYVAWMSTTATQAEQAATQAEAAAAAYEAAFAATVPPPAIAANRAQLATL 122 Query 121 IATNFFGQNTAAIAATEAQYAEMWAQDAAAMYGYATASAAAALLTPFSPPRQTTNPAG-- 178 IATN GQNT AIAATEAQY EMWAQDAA MYGYA +SAAA L F+ P QTT+ G Sbjct 123 IATNVLGQNTPAIAATEAQYGEMWAQDAATMYGYAGSSAAATRLPMFTDPTQTTSQDGQA 182 Query 179 --------LTAQAAAVSQATDPLSLLIETVTQALQALTIPS------------FIPEDFT 218 T +A QAT +S L V ALQ L+ P+ + + Sbjct 183 RQAAAVAQATGTSAGNQQAT--VSQLNTAVPNALQTLSSPTESSTGSTSGLSSILDPNSN 240 Query 219 FLDAIFAGYATVGVTQDVESFVAGTIGAESNLGLLNVGDENPAEVTPGDFGIGELVSATS 278 F + I + A + Q V++ + T+ S L ++ P GIG Sbjct 241 FWNTITSTGA-LDPAQVVQTVTSSTLIGASTSALNDLASGAPVAT-----GIGTSAQ--- 291 Query 279 PGGGVSASGAGGAASVGNTVLASVGRANSIGQLSVPPSWAAPSTRPVSALSPAGLTTLPG 338 S SG G + G +V A +GRA+ +G LSVPPSWA P+ PV++ P+ L P Sbjct 292 -----SLSGLAGVGNAGASVSAGLGRASLVGPLSVPPSWAPPA--PVASPLPSALGGTPM 344 Query 339 T---DVAEHGMPGVPGVPVAAGRASGVLPRYGVRLTVMAHPPAAG 380 GMPG+P P+ +P+YG R + PPAAG Sbjct 345 VAPPPAMAAGMPGMPFSPMGNHGLGRAVPQYGFRPNFVVRPPAAG 389 >gi|342861296|ref|ZP_08717944.1| PPE family protein [Mycobacterium colombiense CECT 3035] gi|342131196|gb|EGT84477.1| PPE family protein [Mycobacterium colombiense CECT 3035] Length=395 Score = 210 bits (535), Expect = 3e-52, Method: Compositional matrix adjust. Identities = 162/406 (40%), Positives = 218/406 (54%), Gaps = 38/406 (9%) Query 1 MDFALLPPEVNSARMYTGPGAGSLLAAAGGWDSLAAELATTAEAYGSVLSGLAALHWRGP 60 +DFA LPPE+NSARMY+GPG+G +LAAA W+++AAE+ A +YGSV++ L++ W GP Sbjct 2 LDFAALPPEINSARMYSGPGSGPMLAAAAAWNTMAAEMRAAAASYGSVVTELSSEGWLGP 61 Query 61 AAESMAVTAAPYIGWLYTTAEKTQQTAIQARAAALAFEQAYAMTLPPPVVAANRIQLLAL 120 ++ SM AAPY+ WL TA + ++ QA AAA A+E A+AMT+PP VVAANR QL L Sbjct 62 SSMSMLAAAAPYLAWLDGTATQAEEVGSQAFAAATAYESAFAMTVPPAVVAANRAQLAML 121 Query 121 IATNFFGQNTAAIAATEAQYAEMWAQDAAAMYGYATASAAAALLTPFSPPRQTTNPAGLT 180 +ATN FGQNT AIAATEAQYAEMWAQDA AM GYATAS+AAA TP + P+ TN G+ Sbjct 122 VATNIFGQNTPAIAATEAQYAEMWAQDAGAMNGYATASSAAAQFTPLATPQSNTNADGVA 181 Query 181 AQAAAVSQATDPLSLLIETVTQALQALTIPSFIPEDFTFLDAIFAG--YATVGVTQDVES 238 Q AV+Q + +++ + + + S ++L + +G + G + Sbjct 182 GQTNAVAQVAQTPAGAVQSNLSSAASGSSSSSPGSVSSYLAGLLSGSDNSAFGTFTNGNF 241 Query 239 FVAGTIGAESNLGLLNVGDENPAEVTPGDFGIGELVSATSPGG----------------- 281 F + G L G NP + G+ AT+ GG Sbjct 242 FSTAVVN-----GALAGGPFNPQFIISSLQGVLAAQHATALGGLGDFAADADGVAAADLA 296 Query 282 --GVSASGAGGAASVGNTVLASVGRANSIGQLSVPPSWAA-----PSTRPVSALSPAGLT 334 V ++G GGA+ A VG A+ +G +SVP SWA+ P V A GLT Sbjct 297 SNTVGSAGLGGAS-------AGVGNAHLVGSMSVPQSWASAANINPGQTAVQATGVTGLT 349 Query 335 TLPGTDVAEHGMPGVPGVPVAAGRASGVLPRYGVRLTVMAHPPAAG 380 A + R +P+YG R VM PPAAG Sbjct 350 DAGAAPAAGGPGGVAGPMGGTGRRLRRAIPKYGFRPVVMPRPPAAG 395 >gi|183982689|ref|YP_001850980.1| PPE family protein [Mycobacterium marinum M] gi|183176015|gb|ACC41125.1| PPE family protein [Mycobacterium marinum M] Length=409 Score = 209 bits (533), Expect = 4e-52, Method: Compositional matrix adjust. Identities = 182/415 (44%), Positives = 227/415 (55%), Gaps = 46/415 (11%) Query 1 MDFALLPPEVNSARMYTGPGAGSLLAAAGGWDSLAAELATTAEAYGSVLSGLAALHWRGP 60 MDF LPPEVNS RMY+GPG+ +LAA WD ++AE+ TA AY SVLS L + W GP Sbjct 6 MDFGALPPEVNSLRMYSGPGSAPMLAAMAAWDDVSAEMLLTAAAYESVLSALLSDGWLGP 65 Query 61 AAESMAVTAAPYIGWLYTTAEKTQQTAIQARAAALAFEQAYAMTLPPPVVAANRIQLLAL 120 A+ +MA AAPY+ WL T + QTA QA AAA AFE A+AMT+PP VVAANR+QLL L Sbjct 66 ASAAMAAAAAPYVTWLSATGLQAAQTAGQAAAAAAAFEAAFAMTVPPSVVAANRVQLLTL 125 Query 121 IATNFFGQNTAAIAATEAQYAEMWAQDAAAMYGYATASAAAALLTPFSPPRQTTNPAGL- 179 +ATNF G NT AIAATEA+YAEMWAQDA AMYGYA SA A+ L PFS P T + +GL Sbjct 126 VATNFLGINTPAIAATEAEYAEMWAQDATAMYGYAAGSAVASTLEPFSEPAHTASRSGLA 185 Query 180 TAQAAAVSQATDPLSLLIETVTQALQALTIPSFIPEDFTFLDAIFAGYATVGVTQDVESF 239 AA A+ + L +T L + +P+ + A A G+ D+ +F Sbjct 186 GQTAAVAQAASTAMGGLTQTELPQLMS-AVPASLQGLAAPAAAPLDTIAGSGLLADILNF 244 Query 240 VAGTIGA------ESNL--GLLNVGDENPAEVTP---------------GDFGIGELVSA 276 + G G S+L G+++ G P V P G GI ++ Sbjct 245 LDGNDGNAFGIFLNSSLANGVISAGYTAPGIVVPAVTSAMADVNALALDGLPGIALPITG 304 Query 277 TSPGGG------VSASGAGGAASVGNTVLASVGRANSIGQLSVPPSWAAP---STRPVSA 327 + G V SG GG A A +A +G+LSVPPSWA + +A Sbjct 305 SDSGDAVWTRMTVPQSGLGGVA-------AGTNQATMVGRLSVPPSWAGTTEVTDHVATA 357 Query 328 LSPAGLTTLPGTDVAEHGMPGVPGVPV--AAGRASGVLPRYGVRLTVMAHPPAAG 380 L AG T P A MPGVPGVP A R+ G PRYG RLT+M P + G Sbjct 358 LPGAGTATAP---EASAAMPGVPGVPAPGAYARSYGTGPRYGFRLTIMPRPLSGG 409 >gi|296170357|ref|ZP_06851948.1| PPE family protein [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295895080|gb|EFG74799.1| PPE family protein [Mycobacterium parascrofulaceum ATCC BAA-614] Length=459 Score = 207 bits (526), Expect = 3e-51, Method: Compositional matrix adjust. Identities = 161/347 (47%), Positives = 207/347 (60%), Gaps = 29/347 (8%) Query 1 MDFALLPPEVNSARMYTGPGAGSLLAAAGGWDSLAAELATTAEAYGSVLSGLAALHWRGP 60 MD+ +LPPE+NSARMY GPG+GS+L AA WD LA EL + A +Y +V+SGL W GP Sbjct 1 MDYGVLPPEINSARMYAGPGSGSMLTAAAAWDELATELRSIAASYSAVISGLTTA-WLGP 59 Query 61 AAESMAVTAAPYIGWLYTTAEKTQQTAIQARAAALAFEQAYAMTLPPPVVAANRIQLLAL 120 ++ MA AAPY WL TA + +Q+ QARAAA A+E A+A T+PPPV+ NR +L +L Sbjct 60 SSTRMAAAAAPYAAWLNATAAQAEQSGSQARAAAAAYEAAFAATVPPPVIETNRAELESL 119 Query 121 IATNFFGQNTAAIAATEAQYAEMWAQDAAAMYGYATASAAAALLTPFSPPRQTTNPAGLT 180 IATN FGQNTAAIAA EA+YA MWAQDAAAMYGYA SAAAA +TPF PP Q TNPAG Sbjct 120 IATNTFGQNTAAIAANEARYARMWAQDAAAMYGYAGQSAAAAAVTPFDPPAQNTNPAGTA 179 Query 181 AQAAAVSQATDP---------LSLLIETVTQALQALTIPSFI----PEDFTFLDAIFAGY 227 Q AAVSQ LS L AL++L P+ + + Sbjct 180 GQTAAVSQVVGTSAGTNSQAALSHLTSATPSALRSLAAPAAVNPPSASSLASFLSSLNSS 239 Query 228 ATVGVTQDVESFVAGTIGAESNLGLLNVGDENPAEVTPGDFGIGEL---VSATSPGGGVS 284 + +VE + A L +G + G +G+L V A +PG Sbjct 240 PLAKLAGNVELIPKAVLPANDVLISTIMG------LVIGARHLGDLTVAVKAATPG---L 290 Query 285 ASGAGGAA-SVGNTVLASVGRANSIGQLSVPPSWAA--PSTRPVSAL 328 A+G G AA ++G+TV A+VG+A +G L+VPPSWA P+ R V+A+ Sbjct 291 AAGLGYAAPALGSTVSATVGQAGLVGGLAVPPSWAVATPAIRTVAAV 337 >gi|240169314|ref|ZP_04747973.1| PPE family protein [Mycobacterium kansasii ATCC 12478] Length=383 Score = 204 bits (519), Expect = 2e-50, Method: Compositional matrix adjust. Identities = 175/393 (45%), Positives = 211/393 (54%), Gaps = 25/393 (6%) Query 1 MDFALLPPEVNSARMYTGPGAGSLLAAAGGWDSLAAELATTAEAYGSVLSGLAALHWRGP 60 MDF LPPEVNS RMY GPG GSL AAAG WDSLAAEL TA Y SV++GL + W GP Sbjct 1 MDFGALPPEVNSVRMYAGPGPGSLAAAAGMWDSLAAELHATAGHYRSVIAGLTSGRWLGP 60 Query 61 AAESMAVTAAPYIGWLYTTAEKTQQTAIQARAAALAFEQAYAMTLPPPVVAANRIQLLAL 120 A+ SMA PY+ W A + +TA QA A +E A+AMT+PPPVVAANR L AL Sbjct 61 ASLSMASALGPYVAWTAGVAARAAETASQAVLAVEGYEAAFAMTVPPPVVAANRALLAAL 120 Query 121 IATNFFGQNTAAIAATEAQYAEMWAQDAAAMYGYATASAAAALLTPFSPPRQTTNPAGLT 180 +ATNFFGQN+ AIAATEA+Y MWAQDAAAMY YA SA A LT P + NP GL Sbjct 121 VATNFFGQNSTAIAATEAEYGVMWAQDAAAMYEYAANSATACELTLLISPPEVINPVGLA 180 Query 181 AQA-----AAVSQATDPLSL--LIETVTQALQALTIP-SFIPEDFTFLDAIFAGYATVGV 232 Q+ AA + + LSL L+ +V L L P S + E + L ATV V Sbjct 181 GQSTAVAHAAAASGAEQLSLAGLVSSVPAMLDGLASPLSGLAESSSSLMPTL---ATVPV 237 Query 233 TQDVESFVAGTIGAESNLGLLNVGDENPAEVTPGDFGIGELVSATSPGGGVSASGAGGAA 292 F+A S +L + + + G +SGAG A Sbjct 238 YALPSYFMAAATPLYSLSSILGMAQTAQGLASGAAAAAQAAAEGAA---GAVSSGAGLIA 294 Query 293 SVGNTVLASVGRANSIGQLSVPPSWAAPSTRPVSALSPAGLTTLPGTDVAEHGMPGVPGV 352 SVG V+ S+G A S+G LSVP SW S P + + A LP A + P + G Sbjct 295 SVGPGVVGSMGNAASLGPLSVPASWT--SVIPTANMGAA--AALPNGLDAANAAPSLLGA 350 Query 353 P-----VAAGRASGVLPRYGVRLTVMAHPPAAG 380 GR+ G PRYG+ TVM PPAAG Sbjct 351 APRSGLTGPGRSVG--PRYGIVPTVMTRPPAAG 381 >gi|240171463|ref|ZP_04750122.1| PPE family protein [Mycobacterium kansasii ATCC 12478] Length=408 Score = 204 bits (518), Expect = 3e-50, Method: Compositional matrix adjust. Identities = 185/411 (46%), Positives = 233/411 (57%), Gaps = 34/411 (8%) Query 1 MDFALLPPEVNSARMYTGPGAGSLLAAAGGWDSLAAELATTAEAYGSVLSGLAALHWRGP 60 MD+A LPPEVNSARMYTGPG G +LAAA WDSL+ EL++ A+ Y V++G+ + WRGP Sbjct 1 MDYAALPPEVNSARMYTGPGCGPILAAALAWDSLSGELSSAAKEYSIVVTGMTSGPWRGP 60 Query 61 AAESMAVTAAPYIGWLYTTAEKTQQTAIQARAAALAFEQAYAMTLPPPVVAANRIQLLAL 120 A+ +MA PYI WL TTA + Q A QA+AAA A+E A+AMT+PP +AANR QL +L Sbjct 61 ASSAMAAAVGPYIAWLATTASQAFQAAGQAKAAAAAYEAAFAMTVPPAEIAANRAQLASL 120 Query 121 IATNFFGQNTAAIAATEAQYAEMWAQDAAAMYGYATASAAAALLTPFSP-PRQTTNPAGL 179 +ATN GQNT AIAATEA Y +MWAQDAAAMYGYA +SAAA+ L PF+ P + AG Sbjct 121 VATNLLGQNTPAIAATEALYGQMWAQDAAAMYGYAASSAAASQLAPFADAPMTASGDAGA 180 Query 180 TAQAA-AVSQATD-PLSLLIETVTQALQALTIP---SFIPEDFTFL------DAIFAGYA 228 QAA A S A+ LS +++TV LQ L P S D L D I A Sbjct 181 LVQAASATSTASQGALSQVMQTVPATLQGLASPTGASTAGADLLGLLGSGMEDWIGLSGA 240 Query 229 TVGVTQDVESFVAGTIGAESNLGLLNV--GDENPAEVTPGDFGIGELVSAT--------- 277 + + +F++GT G+ + L +V + TPG+F +G L A Sbjct 241 DLSSPAGILAFLSGTDGSPLGVALSSVYFNALSSGFYTPGNF-LGTLADAVGLQGAEAVE 299 Query 278 ----SPGGGVSASGAGGAASVGNTVLASVGRANSIGQLSVPPSWAAPSTR--PVSALSPA 331 ++ VG V A VG A +IG LSVPP+W A S+ SAL Sbjct 300 EAAAGAAEAAASELGAATGGVGGAVSAGVGNAATIGPLSVPPAWTATSSLGAAASALPSN 359 Query 332 GLTTLPGTDVAEHGMPGVPGVPVAAGRASGV--LPRYGVRLTVMAHPPAAG 380 T PG A M G G+P++ A G PRYG R TVM HPPAAG Sbjct 360 AAATAPGITGATPSMLG--GMPLSGLGARGFAEAPRYGFRPTVMVHPPAAG 408 Lambda K H 0.314 0.128 0.370 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 734326436450 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40