BLASTP 2.2.25+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.



Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
           15,229,318 sequences; 5,219,829,388 total letters



Query= Rv3160c

Length=213
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

gi|15842737|ref|NP_337774.1|  TetR family transcriptional regulat...   419    1e-115
gi|167970173|ref|ZP_02552450.1|  transcriptional regulator, TetR ...   418    3e-115
gi|15610296|ref|NP_217676.1|  TetR family transcriptional regulat...   418    3e-115
gi|340628137|ref|YP_004746589.1|  putative transcriptional regula...   417    6e-115
gi|240168071|ref|ZP_04746730.1|  TetR family transcriptional regu...   251    4e-65 
gi|54024192|ref|YP_118434.1|  putative transcriptional regulator ...  77.4    1e-12 
gi|333991305|ref|YP_004523919.1|  transcription regulator AmtR [M...  76.3    3e-12 
gi|169631167|ref|YP_001704816.1|  TetR family transcriptional reg...  73.6    2e-11 
gi|118470544|ref|YP_888577.1|  transcription regulator AmtR [Myco...  73.2    2e-11 
gi|118472773|ref|YP_885989.1|  TetR family transcriptional regula...  72.0    5e-11 
gi|262203753|ref|YP_003274961.1|  TetR family transcriptional reg...  72.0    5e-11 
gi|226366296|ref|YP_002784079.1|  TetR family transcriptional reg...  71.6    8e-11 
gi|111023870|ref|YP_706842.1|  MalT family transcriptional regula...  71.2    8e-11 
gi|312139511|ref|YP_004006847.1|  tetr family transcriptional reg...  69.3    3e-10 
gi|317505887|ref|ZP_07963727.1|  tetR family bacterial regulatory...  68.9    5e-10 
gi|325672599|ref|ZP_08152295.1|  TetR family transcriptional regu...  68.6    5e-10 
gi|229493562|ref|ZP_04387347.1|  transcriptional regulator, MalT ...  67.4    1e-09 
gi|226306438|ref|YP_002766398.1|  TetR family transcriptional reg...  66.2    3e-09 
gi|119964272|ref|YP_946013.1|  TetR family transcriptional regula...  65.1    6e-09 
gi|326329894|ref|ZP_08196209.1|  transcriptional regulator, TetR ...  65.1    6e-09 
gi|146275919|ref|YP_001166079.1|  TetR family transcriptional reg...  65.1    6e-09 
gi|302342059|ref|YP_003806588.1|  TetR family transcriptional reg...  64.3    1e-08 
gi|343926067|ref|ZP_08765579.1|  putative TetR family transcripti...  63.9    1e-08 
gi|163760735|ref|ZP_02167815.1|  transcriptional regulator, TetR ...  63.9    1e-08 
gi|194016628|ref|ZP_03055242.1|  TetR family transcriptional regu...  63.9    1e-08 
gi|333918744|ref|YP_004492325.1|  transcription regulator AmtR [A...  63.9    2e-08 
gi|227820121|ref|YP_002824092.1|  TetR family transcriptional reg...  63.5    2e-08 
gi|29833243|ref|NP_827877.1|  TetR family transcriptional regulat...  63.2    3e-08 
gi|257791035|ref|YP_003181641.1|  TetR family transcriptional reg...  61.6    7e-08 
gi|325830706|ref|ZP_08164090.1|  transcriptional regulator, TetR ...  61.6    8e-08 
gi|311900046|dbj|BAJ32454.1|  putative TetR family transcriptiona...  61.6    8e-08 
gi|108798810|ref|YP_639007.1|  TetR family transcriptional regula...  61.2    1e-07 
gi|296139307|ref|YP_003646550.1|  TetR family transcriptional reg...  60.5    1e-07 
gi|118468120|ref|YP_885944.1|  TetR family transcriptional regula...  60.1    2e-07 
gi|229494137|ref|ZP_04387900.1|  transcriptional regulator, TetR ...  60.1    2e-07 
gi|84501810|ref|ZP_00999968.1|  transcriptional regulator, TetR f...  60.1    2e-07 
gi|288922880|ref|ZP_06417043.1|  transcriptional regulator, TetR ...  60.1    2e-07 
gi|271968981|ref|YP_003343177.1|  TetR family transcriptional reg...  60.1    2e-07 
gi|295695869|ref|YP_003589107.1|  TetR family transcriptional reg...  60.1    2e-07 
gi|163854670|ref|YP_001628968.1|  TetR family transcriptional reg...  59.3    3e-07 
gi|300784545|ref|YP_003764836.1|  TetR family transcriptional reg...  59.3    4e-07 
gi|145225177|ref|YP_001135855.1|  TetR family transcriptional reg...  59.3    4e-07 
gi|300767812|ref|ZP_07077722.1|  transcription regulator [Lactoba...  59.3    4e-07 
gi|154247994|ref|YP_001418952.1|  TetR family transcriptional reg...  58.5    5e-07 
gi|229017860|ref|ZP_04174743.1|  Transcriptional regulator, TetR ...  58.5    5e-07 
gi|229076815|ref|ZP_04209725.1|  Transcriptional regulator, TetR ...  58.5    6e-07 
gi|300781697|ref|ZP_07091551.1|  transcription regulator AmtR [Co...  58.5    6e-07 
gi|209526291|ref|ZP_03274820.1|  transcriptional regulator, TetR ...  58.5    6e-07 
gi|311895237|dbj|BAJ27645.1|  putative TetR family transcriptiona...  58.5    7e-07 
gi|119492809|ref|ZP_01623895.1|  Transcriptional Regulator, TetR ...  58.5    7e-07 


>gi|15842737|ref|NP_337774.1| TetR family transcriptional regulator [Mycobacterium tuberculosis 
CDC1551]
 gi|13883060|gb|AAK47588.1| transcriptional regulator, TetR family [Mycobacterium tuberculosis 
CDC1551]
Length=225

 Score =  419 bits (1077),  Expect = 1e-115, Method: Compositional matrix adjust.
 Identities = 213/213 (100%), Positives = 213/213 (100%), Gaps = 0/213 (0%)

Query  1    MPRQAGRWSPTALRILGAAAELIALRGYSSTSTRDIAAAVGVEQPAIYKHFSAKRDILAA  60
            MPRQAGRWSPTALRILGAAAELIALRGYSSTSTRDIAAAVGVEQPAIYKHFSAKRDILAA
Sbjct  13   MPRQAGRWSPTALRILGAAAELIALRGYSSTSTRDIAAAVGVEQPAIYKHFSAKRDILAA  72

Query  61   LVRLAVEWPLELFGHITAMPVPAVVKLHRWLTESLDHLHASPYVLVSILITPDLHQESFV  120
            LVRLAVEWPLELFGHITAMPVPAVVKLHRWLTESLDHLHASPYVLVSILITPDLHQESFV
Sbjct  73   LVRLAVEWPLELFGHITAMPVPAVVKLHRWLTESLDHLHASPYVLVSILITPDLHQESFV  132

Query  121  AERELVAEMERALVGLIETGQGEGDVRAMHPLSAARLVQALFDALALPEFAVSPDEIVEF  180
            AERELVAEMERALVGLIETGQGEGDVRAMHPLSAARLVQALFDALALPEFAVSPDEIVEF
Sbjct  133  AERELVAEMERALVGLIETGQGEGDVRAMHPLSAARLVQALFDALALPEFAVSPDEIVEF  192

Query  181  AMTALLSDPDRLAEIRAAADALEIQTAPPDRGL  213
            AMTALLSDPDRLAEIRAAADALEIQTAPPDRGL
Sbjct  193  AMTALLSDPDRLAEIRAAADALEIQTAPPDRGL  225


>gi|167970173|ref|ZP_02552450.1| transcriptional regulator, TetR family protein [Mycobacterium 
tuberculosis H37Ra]
 gi|254365785|ref|ZP_04981830.1| hypothetical transcriptional regulatory protein (probably tetR-family) 
[Mycobacterium tuberculosis str. Haarlem]
 gi|254552250|ref|ZP_05142697.1| TetR family transcriptional regulator [Mycobacterium tuberculosis 
'98-R604 INH-RIF-EM']
 gi|289746973|ref|ZP_06506351.1| transcriptional regulator [Mycobacterium tuberculosis 02_1987]
 gi|134151298|gb|EBA43343.1| hypothetical transcriptional regulatory protein (probably tetR-family) 
[Mycobacterium tuberculosis str. Haarlem]
 gi|289687501|gb|EFD54989.1| transcriptional regulator [Mycobacterium tuberculosis 02_1987]
Length=220

 Score =  418 bits (1074),  Expect = 3e-115, Method: Compositional matrix adjust.
 Identities = 213/213 (100%), Positives = 213/213 (100%), Gaps = 0/213 (0%)

Query  1    MPRQAGRWSPTALRILGAAAELIALRGYSSTSTRDIAAAVGVEQPAIYKHFSAKRDILAA  60
            MPRQAGRWSPTALRILGAAAELIALRGYSSTSTRDIAAAVGVEQPAIYKHFSAKRDILAA
Sbjct  8    MPRQAGRWSPTALRILGAAAELIALRGYSSTSTRDIAAAVGVEQPAIYKHFSAKRDILAA  67

Query  61   LVRLAVEWPLELFGHITAMPVPAVVKLHRWLTESLDHLHASPYVLVSILITPDLHQESFV  120
            LVRLAVEWPLELFGHITAMPVPAVVKLHRWLTESLDHLHASPYVLVSILITPDLHQESFV
Sbjct  68   LVRLAVEWPLELFGHITAMPVPAVVKLHRWLTESLDHLHASPYVLVSILITPDLHQESFV  127

Query  121  AERELVAEMERALVGLIETGQGEGDVRAMHPLSAARLVQALFDALALPEFAVSPDEIVEF  180
            AERELVAEMERALVGLIETGQGEGDVRAMHPLSAARLVQALFDALALPEFAVSPDEIVEF
Sbjct  128  AERELVAEMERALVGLIETGQGEGDVRAMHPLSAARLVQALFDALALPEFAVSPDEIVEF  187

Query  181  AMTALLSDPDRLAEIRAAADALEIQTAPPDRGL  213
            AMTALLSDPDRLAEIRAAADALEIQTAPPDRGL
Sbjct  188  AMTALLSDPDRLAEIRAAADALEIQTAPPDRGL  220


>gi|15610296|ref|NP_217676.1| TetR family transcriptional regulator [Mycobacterium tuberculosis 
H37Rv]
 gi|31794337|ref|NP_856830.1| TetR family transcriptional regulator [Mycobacterium bovis AF2122/97]
 gi|121639044|ref|YP_979268.1| TetR family transcriptional regulator [Mycobacterium bovis BCG 
str. Pasteur 1173P2]
 68 more sequence titles
 Length=213

 Score =  418 bits (1074),  Expect = 3e-115, Method: Compositional matrix adjust.
 Identities = 213/213 (100%), Positives = 213/213 (100%), Gaps = 0/213 (0%)

Query  1    MPRQAGRWSPTALRILGAAAELIALRGYSSTSTRDIAAAVGVEQPAIYKHFSAKRDILAA  60
            MPRQAGRWSPTALRILGAAAELIALRGYSSTSTRDIAAAVGVEQPAIYKHFSAKRDILAA
Sbjct  1    MPRQAGRWSPTALRILGAAAELIALRGYSSTSTRDIAAAVGVEQPAIYKHFSAKRDILAA  60

Query  61   LVRLAVEWPLELFGHITAMPVPAVVKLHRWLTESLDHLHASPYVLVSILITPDLHQESFV  120
            LVRLAVEWPLELFGHITAMPVPAVVKLHRWLTESLDHLHASPYVLVSILITPDLHQESFV
Sbjct  61   LVRLAVEWPLELFGHITAMPVPAVVKLHRWLTESLDHLHASPYVLVSILITPDLHQESFV  120

Query  121  AERELVAEMERALVGLIETGQGEGDVRAMHPLSAARLVQALFDALALPEFAVSPDEIVEF  180
            AERELVAEMERALVGLIETGQGEGDVRAMHPLSAARLVQALFDALALPEFAVSPDEIVEF
Sbjct  121  AERELVAEMERALVGLIETGQGEGDVRAMHPLSAARLVQALFDALALPEFAVSPDEIVEF  180

Query  181  AMTALLSDPDRLAEIRAAADALEIQTAPPDRGL  213
            AMTALLSDPDRLAEIRAAADALEIQTAPPDRGL
Sbjct  181  AMTALLSDPDRLAEIRAAADALEIQTAPPDRGL  213


>gi|340628137|ref|YP_004746589.1| putative transcriptional regulatory protein [Mycobacterium canettii 
CIPT 140010059]
 gi|340006327|emb|CCC45506.1| putative transcriptional regulatory protein (probably TETR-family) 
[Mycobacterium canettii CIPT 140010059]
Length=213

 Score =  417 bits (1072),  Expect = 6e-115, Method: Compositional matrix adjust.
 Identities = 212/213 (99%), Positives = 213/213 (100%), Gaps = 0/213 (0%)

Query  1    MPRQAGRWSPTALRILGAAAELIALRGYSSTSTRDIAAAVGVEQPAIYKHFSAKRDILAA  60
            MPRQAGRWSPTALRILGAAAELIA+RGYSSTSTRDIAAAVGVEQPAIYKHFSAKRDILAA
Sbjct  1    MPRQAGRWSPTALRILGAAAELIAVRGYSSTSTRDIAAAVGVEQPAIYKHFSAKRDILAA  60

Query  61   LVRLAVEWPLELFGHITAMPVPAVVKLHRWLTESLDHLHASPYVLVSILITPDLHQESFV  120
            LVRLAVEWPLELFGHITAMPVPAVVKLHRWLTESLDHLHASPYVLVSILITPDLHQESFV
Sbjct  61   LVRLAVEWPLELFGHITAMPVPAVVKLHRWLTESLDHLHASPYVLVSILITPDLHQESFV  120

Query  121  AERELVAEMERALVGLIETGQGEGDVRAMHPLSAARLVQALFDALALPEFAVSPDEIVEF  180
            AERELVAEMERALVGLIETGQGEGDVRAMHPLSAARLVQALFDALALPEFAVSPDEIVEF
Sbjct  121  AERELVAEMERALVGLIETGQGEGDVRAMHPLSAARLVQALFDALALPEFAVSPDEIVEF  180

Query  181  AMTALLSDPDRLAEIRAAADALEIQTAPPDRGL  213
            AMTALLSDPDRLAEIRAAADALEIQTAPPDRGL
Sbjct  181  AMTALLSDPDRLAEIRAAADALEIQTAPPDRGL  213


>gi|240168071|ref|ZP_04746730.1| TetR family transcriptional regulator [Mycobacterium kansasii 
ATCC 12478]
Length=214

 Score =  251 bits (642),  Expect = 4e-65, Method: Compositional matrix adjust.
 Identities = 130/207 (63%), Positives = 167/207 (81%), Gaps = 1/207 (0%)

Query  1    MPRQAGRWSPTALRILGAAAELIALRGYSSTSTRDIAAAVGVEQPAIYKHFSAKRDILAA  60
            M  +A R SPTA RIL AAAELI+LRGYS+TSTR+IAAAVGVEQPA+YKHFS+K+DILAA
Sbjct  1    MSGEAARRSPTADRILRAAAELISLRGYSATSTREIAAAVGVEQPALYKHFSSKKDILAA  60

Query  61   LVRLAVEWPLELFGHITAMPVPAVVKLHRWLTESLDHLHASPYVLVSILITPDLHQ-ESF  119
            LVRLA+E PL +   + A+  PAVVKLHRWL E+ ++++ SP VL +++ITP+L Q ++F
Sbjct  61   LVRLALERPLAVADELAAVRAPAVVKLHRWLQEAYEYVNRSPNVLAALIITPELQQDDAF  120

Query  120  VAERELVAEMERALVGLIETGQGEGDVRAMHPLSAARLVQALFDALALPEFAVSPDEIVE  179
             AE+ LV+++E  +V LI  GQ EGDVR ++P+SAARL++A+FDA+  P+ AV P EIVE
Sbjct  121  AAEQALVSKIEPVIVDLIRAGQDEGDVRELNPVSAARLIEAMFDAVTFPDLAVDPVEIVE  180

Query  180  FAMTALLSDPDRLAEIRAAADALEIQT  206
            F + ALLSDP RL EIR+AADALEI T
Sbjct  181  FTLVALLSDPARLPEIRSAADALEIST  207


>gi|54024192|ref|YP_118434.1| putative transcriptional regulator [Nocardia farcinica IFM 10152]
 gi|54015700|dbj|BAD57070.1| putative transcriptional regulator [Nocardia farcinica IFM 10152]
Length=227

 Score = 77.4 bits (189),  Expect = 1e-12, Method: Compositional matrix adjust.
 Identities = 49/122 (41%), Positives = 70/122 (58%), Gaps = 1/122 (0%)

Query  2    PRQAGRWSPTALRILGAAAELIALRGYSSTSTRDIAAAVGVEQPAIYKHFSAKRDILAAL  61
            PR+    +P A  IL AAAEL   +GY+STSTR +A AVG+ Q ++Y HF+AK DIL AL
Sbjct  19   PRRRQGRTPRA-EILDAAAELFTTQGYASTSTRAVADAVGIRQASLYHHFAAKDDILEAL  77

Query  62   VRLAVEWPLELFGHITAMPVPAVVKLHRWLTESLDHLHASPYVLVSILITPDLHQESFVA  121
            +   V  PL L   + A PV   V+L+      +  L ++ + L ++ + P+L    F A
Sbjct  78   LAETVSGPLALAERLRAEPVAPAVRLYALARFDVRQLCSARWNLGALYLLPELRSARFAA  137

Query  122  ER  123
             R
Sbjct  138  FR  139


>gi|333991305|ref|YP_004523919.1| transcription regulator AmtR [Mycobacterium sp. JDM601]
 gi|333487273|gb|AEF36665.1| transcription regulator AmtR [Mycobacterium sp. JDM601]
Length=219

 Score = 76.3 bits (186),  Expect = 3e-12, Method: Compositional matrix adjust.
 Identities = 47/115 (41%), Positives = 63/115 (55%), Gaps = 0/115 (0%)

Query  15   ILGAAAELIALRGYSSTSTRDIAAAVGVEQPAIYKHFSAKRDILAALVRLAVEWPLELFG  74
            IL AAAEL    GYS TSTR IA AVG+ Q ++Y HF+AK DIL AL+   V+  L+L  
Sbjct  25   ILDAAAELFTTIGYSGTSTRRIAEAVGMRQASLYHHFAAKEDILDALLAGTVDASLQLAA  84

Query  75   HITAMPVPAVVKLHRWLTESLDHLHASPYVLVSILITPDLHQESFVAERELVAEM  129
             + A   PA  +LH  +      L +  + L S+ + P+L  E F   R    E+
Sbjct  85   ELRAEDGPAAPRLHTLVVADTAQLCSGAWNLGSLYLLPELRVERFAVFRRRRDEL  139


>gi|169631167|ref|YP_001704816.1| TetR family transcriptional regulator [Mycobacterium abscessus 
ATCC 19977]
 gi|169243134|emb|CAM64162.1| Putative transcriptional regulator, TetR family [Mycobacterium 
abscessus]
Length=219

 Score = 73.6 bits (179),  Expect = 2e-11, Method: Compositional matrix adjust.
 Identities = 42/110 (39%), Positives = 62/110 (57%), Gaps = 0/110 (0%)

Query  15   ILGAAAELIALRGYSSTSTRDIAAAVGVEQPAIYKHFSAKRDILAALVRLAVEWPLELFG  74
            IL A+AEL    G+++T+TR IA +VG++Q ++Y HF  K DIL AL+ + ++ PL    
Sbjct  21   ILDASAELFTTDGFAATTTRRIAESVGIQQASLYYHFKTKDDILDALLAMTIDQPLHYAA  80

Query  75   HITAMPVPAVVKLHRWLTESLDHLHASPYVLVSILITPDLHQESFVAERE  124
             I   P   VV+L+         L AS + L ++ + PDL  E F A R 
Sbjct  81   LIADRPEAPVVRLYALALGDAAQLAASRWNLGALYLLPDLRAERFSAFRR  130


>gi|118470544|ref|YP_888577.1| transcription regulator AmtR [Mycobacterium smegmatis str. MC2 
155]
 gi|118171831|gb|ABK72727.1| transcription regulator AmtR [Mycobacterium smegmatis str. MC2 
155]
Length=225

 Score = 73.2 bits (178),  Expect = 2e-11, Method: Compositional matrix adjust.
 Identities = 74/207 (36%), Positives = 99/207 (48%), Gaps = 20/207 (9%)

Query  15   ILGAAAELIALRGYSSTSTRDIAAAVGVEQPAIYKHFSAKRDILAALVRLAVEWPLELFG  74
            IL AAAEL    GY STSTR IA  VGV Q ++Y HF+ K DIL AL+   V+ PLEL  
Sbjct  26   ILDAAAELFTTHGYGSTSTRRIADEVGVRQASLYHHFATKDDILDALLAGTVDEPLELAH  85

Query  75   HITAMPVPAVVKLHRWLTESLDHLHASPYVLVSILITPDLHQESFVAERELVAEMERALV  134
             +     PA  +LH  +      L A  + L ++ + P+L  + F   R   AE+  A  
Sbjct  86   GLLGESGPAAPRLHALVIYDASQLCAGRWNLGALYLLPELRTDRFAPFRRRRAELRSAYR  145

Query  135  GLIET------GQGEGDVRAMHPLSAARLVQALFDALALPEFAVSPDE----IVEFAMTA  184
             L         G  E D          RLV+++ ++ +  + AV P E    I E A+  
Sbjct  146  SLAAAVIAECGGPPEADDLPF------RLVESVINSRS--DDAVVPPEQPWVIGEGALRV  197

Query  185  LLSDPDRLAEIRAAADALEIQTAPPDR  211
            L  D D  AE+ AAA A  +   PP R
Sbjct  198  LGFDGD-FAEL-AAATASRLGVRPPGR  222


>gi|118472773|ref|YP_885989.1| TetR family transcriptional regulator [Mycobacterium smegmatis 
str. MC2 155]
 gi|118174060|gb|ABK74956.1| transcriptional regulator, TetR family protein, putative [Mycobacterium 
smegmatis str. MC2 155]
Length=225

 Score = 72.0 bits (175),  Expect = 5e-11, Method: Compositional matrix adjust.
 Identities = 64/211 (31%), Positives = 95/211 (46%), Gaps = 11/211 (5%)

Query  8    WSPTALRILGAAAELIALRGYSSTSTRDIAAAVGVEQPAIYKHFSAKRDILAALVRLAVE  67
            W+ T  RIL AA++L A RGY  TSTRDIA AV + QP+++ HF+AK++I   LV L + 
Sbjct  14   WASTRGRILLAASQLFAARGYFGTSTRDIADAVSIRQPSLFHHFTAKQEIFRTLVELDLG  73

Query  68   WPLELFGHITAMPVPAVVKLHRWLTESLDHLHASPYVLVSILITPDLHQESFVAERELVA  127
              ++      A       KLH  +   +  + A P+    +     L    F  ER  + 
Sbjct  74   PSIDRVRQRLAEESTWAEKLHLTVACDVREILAQPFDARGLYQDAVLAMPEFDEERRGID  133

Query  128  EMERALVGLIETGQGEG---DVRAMHPLSAARLVQALFDAL------ALPEFAVSPDEIV  178
                 +  LI +G   G   D  A   L AA  V  +F+ L      A       P +  
Sbjct  134  LFHDLVETLIRSGTDAGEFVDFEASFVLRAANGV--MFETLREQGGPAGRMRVQRPLQAA  191

Query  179  EFAMTALLSDPDRLAEIRAAADALEIQTAPP  209
            +F + A++ DP  L  IRA  +   ++   P
Sbjct  192  DFVLRAVMVDPTDLPRIRAVTENRLVKGVLP  222


>gi|262203753|ref|YP_003274961.1| TetR family transcriptional regulator [Gordonia bronchialis DSM 
43247]
 gi|262087100|gb|ACY23068.1| regulatory protein TetR [Gordonia bronchialis DSM 43247]
Length=214

 Score = 72.0 bits (175),  Expect = 5e-11, Method: Compositional matrix adjust.
 Identities = 54/149 (37%), Positives = 75/149 (51%), Gaps = 4/149 (2%)

Query  15   ILGAAAELIALRGYSSTSTRDIAAAVGVEQPAIYKHFSAKRDILAALVRLAVEWPLELFG  74
            IL AAAEL    GY+ TSTR IA AVG+ Q ++Y +FS K DILA L+   V  PLE   
Sbjct  32   ILDAAAELFTSHGYTGTSTRMIADAVGIRQASMYHYFSTKDDILATLLETTVISPLERAR  91

Query  75   HITAMPVPAVVKLHRWLTESLDHLHASPYVLVSILITPDLHQESFVAERELVAEMERALV  134
            H+     PA+ +L       +  L AS + L ++ + P+L  + F   R    E+  A  
Sbjct  92   HLLTEDGPALERLLDLARFDVTQLAASRWNLGALYLLPELRNDRFSEFRTARTELADAYT  151

Query  135  GLIETGQGE-GDVRAMHPLSAARLVQALF  162
             L     G   D R + P    RLV+++ 
Sbjct  152  QLATEVLGTASDRRNLLPF---RLVESVI  177


>gi|226366296|ref|YP_002784079.1| TetR family transcriptional regulator [Rhodococcus opacus B4]
 gi|226244786|dbj|BAH55134.1| putative TetR family transcriptional regulator [Rhodococcus opacus 
B4]
Length=235

 Score = 71.6 bits (174),  Expect = 8e-11, Method: Compositional matrix adjust.
 Identities = 51/149 (35%), Positives = 74/149 (50%), Gaps = 7/149 (4%)

Query  3    RQAGRWSPTALRILGAAAELIALRGYSSTSTRDIAAAVGVEQPAIYKHFSAKRDILAALV  62
            R+ GR +P    IL AA EL   +G+++TSTR IA  VG+ Q ++Y HF  K +ILAAL+
Sbjct  14   RRPGRTTPE--EILDAAGELFTTKGFAATSTRQIADMVGIRQASLYHHFPNKEEILAALL  71

Query  63   RLAVEWPLELFGHITAMPVPAVVKLHRWLTESLDHLHASPYVLVSILITPDL---HQESF  119
               V   L     ++    PA V+LH   T  +  L  + + L ++ + P+L     E F
Sbjct  72   EETVSPALAAAERLSDADAPATVRLHALATYDVTQLTTTRWNLGALYLLPELLADRFEPF  131

Query  120  VAERELVAEMERALV--GLIETGQGEGDV  146
              +R L+    R L    L E     GD 
Sbjct  132  RTQRTLLRGHYRLLADGALTEMSDASGDT  160


>gi|111023870|ref|YP_706842.1| MalT family transcriptional regulator [Rhodococcus jostii RHA1]
 gi|110823400|gb|ABG98684.1| transcriptional regulator, MalT family protein [Rhodococcus jostii 
RHA1]
Length=235

 Score = 71.2 bits (173),  Expect = 8e-11, Method: Compositional matrix adjust.
 Identities = 53/149 (36%), Positives = 76/149 (52%), Gaps = 7/149 (4%)

Query  3    RQAGRWSPTALRILGAAAELIALRGYSSTSTRDIAAAVGVEQPAIYKHFSAKRDILAALV  62
            R+ G+ +P    IL AA EL   +G+++TSTR IA  VG+ Q ++Y HF  K +ILAAL+
Sbjct  14   RRPGQTTPE--EILDAAGELFTTKGFAATSTRQIAEMVGIRQASLYHHFPNKEEILAALL  71

Query  63   RLAVEWPLELFGHITAMPVPAVVKLHRWLTESLDHLHASPYVLVSILITPDL---HQESF  119
               V   L   G +     PA V+LH   T  +  L A+ + L ++ + P+L     E F
Sbjct  72   EETVSPALAAAGRLADAAAPATVRLHALATYDVTQLTATKWNLGALYLLPELLTDRFEPF  131

Query  120  VAERELVAEMERALV--GLIETGQGEGDV  146
             A+R L+    R L    L E     GD 
Sbjct  132  RAQRTLLRRHYRQLADQALTEITDDSGDT  160


>gi|312139511|ref|YP_004006847.1| tetr family transcriptional regulator [Rhodococcus equi 103S]
 gi|311888850|emb|CBH48162.1| putative TetR family transcriptional regulator [Rhodococcus equi 
103S]
Length=235

 Score = 69.3 bits (168),  Expect = 3e-10, Method: Compositional matrix adjust.
 Identities = 48/131 (37%), Positives = 66/131 (51%), Gaps = 3/131 (2%)

Query  2    PRQAGRWSPTAL---RILGAAAELIALRGYSSTSTRDIAAAVGVEQPAIYKHFSAKRDIL  58
            PR   R  P A     IL AAAEL   RG++ TSTR IA AVG+ Q ++Y HF+ K DIL
Sbjct  9    PRLKTRTRPGATAREEILDAAAELFTTRGFTGTSTRMIADAVGIRQASMYHHFATKDDIL  68

Query  59   AALVRLAVEWPLELFGHITAMPVPAVVKLHRWLTESLDHLHASPYVLVSILITPDLHQES  118
            AAL+   V  PL     +       VV+L+         L  S + L ++ + P++  + 
Sbjct  69   AALLLDTVAGPLACAEMLRQNCPDPVVRLYALTLFDTAQLAESRWNLGALYLLPEVTTDR  128

Query  119  FVAERELVAEM  129
            F   R L  E+
Sbjct  129  FTEFRSLRGEL  139


>gi|317505887|ref|ZP_07963727.1| tetR family bacterial regulatory protein [Segniliparus rugosus 
ATCC BAA-974]
 gi|316255810|gb|EFV15040.1| tetR family bacterial regulatory protein [Segniliparus rugosus 
ATCC BAA-974]
Length=251

 Score = 68.9 bits (167),  Expect = 5e-10, Method: Compositional matrix adjust.
 Identities = 68/204 (34%), Positives = 95/204 (47%), Gaps = 17/204 (8%)

Query  15   ILGAAAELIALRGYSSTSTRDIAAAVGVEQPAIYKHFSAKRDILAALVRLAVEWPLELFG  74
            IL AAAEL    GY+S STR IA + G  Q ++Y +F +K DIL AL+   V+  L L  
Sbjct  54   ILDAAAELFTTEGYASVSTRKIAESAGFRQASLYHYFGSKEDILTALLGQTVDVALALAE  113

Query  75   HITAMPVPAVVKLHRWLTESLDHLHASPYVLVSILITPDLHQESFVAERELVAEMERALV  134
             +      A V+L+       + L  S + L ++ + P++  E FVA      E   AL 
Sbjct  114  RLKDGRESAAVRLYALALSDSEQLITSRWNLGALYLLPEVRAERFVA----FQEKRTALR  169

Query  135  GLIETGQGEGDVRAMH--PLSAARLVQALFDALAL--PEFAVSPD-----EIVEFAMTAL  185
            G  E  Q    V A H  P    RL   L +++ +   EFA +P      E++  A   +
Sbjct  170  GCYE--QLASAVAAEHGAPTGMRRLPFRLVESVIIERAEFAGAPGSGASPELIAEAALRM  227

Query  186  LSDPDRLAEIRAAADALEIQTAPP  209
            L   D L  IR    AL +  APP
Sbjct  228  LGCADGLEAIR--GQALALLDAPP  249


>gi|325672599|ref|ZP_08152295.1| TetR family transcriptional regulator [Rhodococcus equi ATCC 
33707]
 gi|325556476|gb|EGD26142.1| TetR family transcriptional regulator [Rhodococcus equi ATCC 
33707]
Length=235

 Score = 68.6 bits (166),  Expect = 5e-10, Method: Compositional matrix adjust.
 Identities = 48/131 (37%), Positives = 66/131 (51%), Gaps = 3/131 (2%)

Query  2    PRQAGRWSPTAL---RILGAAAELIALRGYSSTSTRDIAAAVGVEQPAIYKHFSAKRDIL  58
            PR   R  P A     IL AAAEL   RG++ TSTR IA AVG+ Q ++Y HF+ K DIL
Sbjct  9    PRLKTRTRPGATAREEILDAAAELFTTRGFTGTSTRMIADAVGIRQASMYHHFATKDDIL  68

Query  59   AALVRLAVEWPLELFGHITAMPVPAVVKLHRWLTESLDHLHASPYVLVSILITPDLHQES  118
            AAL+   V  PL     +       VV+L+         L  S + L ++ + P++  + 
Sbjct  69   AALLLDTVAGPLACAEMLRRNCPDPVVRLYALTLFDTAQLAESRWNLGALYLLPEVTTDR  128

Query  119  FVAERELVAEM  129
            F   R L  E+
Sbjct  129  FAEFRSLRGEL  139


>gi|229493562|ref|ZP_04387347.1| transcriptional regulator, MalT family [Rhodococcus erythropolis 
SK121]
 gi|229319523|gb|EEN85359.1| transcriptional regulator, MalT family [Rhodococcus erythropolis 
SK121]
Length=243

 Score = 67.4 bits (163),  Expect = 1e-09, Method: Compositional matrix adjust.
 Identities = 49/138 (36%), Positives = 70/138 (51%), Gaps = 6/138 (4%)

Query  2    PRQAGRWSPTAL---RILGAAAELIALRGYSSTSTRDIAAAVGVEQPAIYKHFSAKRDIL  58
            PR   R  P       IL AAAEL   RG+++TSTR IA AVG+ Q ++Y HF+ K DIL
Sbjct  12   PRLTARRRPGGTARAEILDAAAELFTTRGFAATSTRHIAEAVGMRQASLYNHFATKDDIL  71

Query  59   AALVRLAVEWPLELFGHITAMPVPAVVKLHRWLTESLDHLHASPYVLVSILITPDLHQE-  117
             AL+   V   L+   ++  +     VKL+         L    + L  + + P+L  + 
Sbjct  72   VALLADTVTPALDFAENLRPLDTAPEVKLYALSYIDAAQLITGRWNLGVLYLLPELRSDR  131

Query  118  --SFVAERELVAEMERAL  133
              SF A+R+ + E  RAL
Sbjct  132  FMSFRADRDRLREQYRAL  149


>gi|226306438|ref|YP_002766398.1| TetR family transcriptional regulator [Rhodococcus erythropolis 
PR4]
 gi|226185555|dbj|BAH33659.1| putative TetR family transcriptional regulator [Rhodococcus erythropolis 
PR4]
Length=240

 Score = 66.2 bits (160),  Expect = 3e-09, Method: Compositional matrix adjust.
 Identities = 49/138 (36%), Positives = 69/138 (50%), Gaps = 6/138 (4%)

Query  2    PRQAGRWSPTAL---RILGAAAELIALRGYSSTSTRDIAAAVGVEQPAIYKHFSAKRDIL  58
            PR   R  P       IL AAAEL   RG+++TSTR IA AVG+ Q ++Y HF+ K DIL
Sbjct  9    PRLTARRRPGGTARAEILDAAAELFTTRGFAATSTRHIAEAVGMRQASLYNHFATKDDIL  68

Query  59   AALVRLAVEWPLELFGHITAMPVPAVVKLHRWLTESLDHLHASPYVLVSILITPDLHQE-  117
             AL+   V   L+   ++        VKL+         L    + L  + + P+L  + 
Sbjct  69   VALLADTVTPALDFAENLRPRGTSPEVKLYALSYIDAAQLITGRWNLGVLYLLPELRSDR  128

Query  118  --SFVAERELVAEMERAL  133
              SF A+R+ + E  RAL
Sbjct  129  FMSFRADRDRLREQYRAL  146


>gi|119964272|ref|YP_946013.1| TetR family transcriptional regulator [Arthrobacter aurescens 
TC1]
 gi|119951131|gb|ABM10042.1| putative transcriptional regulator, TetR family [Arthrobacter 
aurescens TC1]
Length=232

 Score = 65.1 bits (157),  Expect = 6e-09, Method: Compositional matrix adjust.
 Identities = 55/159 (35%), Positives = 80/159 (51%), Gaps = 17/159 (10%)

Query  15   ILGAAAELIALRGYSSTSTRDIAAAVGVEQPAIYKHFSAKRDILAALVRLAVEWPLELFG  74
            IL AAAEL   +G+++TSTR IA AVG+ Q ++Y HFS K +IL  L+   V   L+   
Sbjct  25   ILDAAAELFTGQGFANTSTRAIADAVGIRQSSLYHHFSTKDEILGELLGGTVSTSLDFAR  84

Query  75   HI---TAMPVPAVVKLHRWLTESLDHLHASPYVLVSILITPDLHQESF----VAEREL--  125
             I   +A  V A  +LH  +      L  S + L  +   P+   E F     A +EL  
Sbjct  85   AIRQHSADAVSAAARLHAVVLFDGSQLCNSRWNLGVLYHLPEARAEIFQPFMAARKELRT  144

Query  126  -VAEMERALVGLIETGQGEGDVRAMHPLSAARLVQALFD  163
              +E+ R L  + +  QG GD       +A RLV++L +
Sbjct  145  IYSELGRELARVSDADQGLGD-------TAFRLVESLIN  176


>gi|326329894|ref|ZP_08196209.1| transcriptional regulator, TetR family [Nocardioidaceae bacterium 
Broad-1]
 gi|325952285|gb|EGD44310.1| transcriptional regulator, TetR family [Nocardioidaceae bacterium 
Broad-1]
Length=248

 Score = 65.1 bits (157),  Expect = 6e-09, Method: Compositional matrix adjust.
 Identities = 40/103 (39%), Positives = 57/103 (56%), Gaps = 2/103 (1%)

Query  14   RILGAAAELIALRGYSSTSTRDIAAAVGVEQPAIYKHFSAKRDILAALVRLAVEWPLELF  73
            +IL AAAEL   RGY+ T+TR+IA   G+ Q +IY HF +K +ILA L+  +V+  +E  
Sbjct  48   QILAAAAELFVGRGYAGTTTREIAEGAGLRQASIYYHFGSKEEILAELLERSVQDRVEQA  107

Query  74   GHITAMPVPAV--VKLHRWLTESLDHLHASPYVLVSILITPDL  114
            G I A    A   V L+      +  L A PY +  +   PD+
Sbjct  108  GKIEAGMASATPDVGLYALAVSDMSALVAMPYNIGMLYRLPDV  150


>gi|146275919|ref|YP_001166079.1| TetR family transcriptional regulator [Novosphingobium aromaticivorans 
DSM 12444]
 gi|145322610|gb|ABP64553.1| transcriptional regulator, TetR family [Novosphingobium aromaticivorans 
DSM 12444]
Length=222

 Score = 65.1 bits (157),  Expect = 6e-09, Method: Compositional matrix adjust.
 Identities = 35/85 (42%), Positives = 49/85 (58%), Gaps = 0/85 (0%)

Query  11   TALRILGAAAELIALRGYSSTSTRDIAAAVGVEQPAIYKHFSAKRDILAALVRLAVEWPL  70
            TA RIL  A EL A +GY +TS RDIA+ VG++QP +YKHFS K D+   +   A++  +
Sbjct  22   TANRILDVAEELFARKGYGATSLRDIASQVGLQQPGLYKHFSGKEDLYRQVYERALKPMI  81

Query  71   ELFGHITAMPVPAVVKLHRWLTESL  95
            +L   I   P      L   +T+ L
Sbjct  82   DLMDEILMRPNSDFSDLTDHITDLL  106


>gi|302342059|ref|YP_003806588.1| TetR family transcriptional regulator [Desulfarculus baarsii 
DSM 2075]
 gi|301638672|gb|ADK83994.1| transcriptional regulator, TetR family [Desulfarculus baarsii 
DSM 2075]
Length=196

 Score = 64.3 bits (155),  Expect = 1e-08, Method: Compositional matrix adjust.
 Identities = 52/185 (29%), Positives = 88/185 (48%), Gaps = 17/185 (9%)

Query  15   ILGAAAELIALRGYSSTSTRDIAAAVGVEQPAIYKHFSAKRDILAALVRLAVEWPLELFG  74
            I  AA EL A +G+   ST ++A   GV +  I+ HF  K  IL +L+    +  + + G
Sbjct  11   IRAAAIELFAAKGFQGASTAEVAKLAGVSEGTIFYHFQTKEGILLSLIDDMFDGYVAVIG  70

Query  75   HITAMPVPAVVKLHRWLTESLDHLHASPYVLVSILI--------TPDLHQESFVAERELV  126
               A     +  +  +L   L H+    +  +S+LI          D  Q + V  R  +
Sbjct  71   QSIAEAATGLEAIECYLRGHLRHVE-ERWNEISLLIRDVPPSFKDDDSPQRAHVLSR--I  127

Query  127  AEMERALVGLIETGQGEGDVRAMHPLSAARL----VQALFDALALPEFAVS--PDEIVEF  180
            A++E  +V  IE GQ +G +R   P + AR+    ++ L   +AL +F+++   DE+ +F
Sbjct  128  AQLEALIVAAIEKGQIDGSIRPCDPAAIARILRGRLKGLTSMMALEKFSITEMSDELCQF  187

Query  181  AMTAL  185
               AL
Sbjct  188  CRRAL  192


>gi|343926067|ref|ZP_08765579.1| putative TetR family transcriptional regulator [Gordonia alkanivorans 
NBRC 16433]
 gi|343763993|dbj|GAA12505.1| putative TetR family transcriptional regulator [Gordonia alkanivorans 
NBRC 16433]
Length=213

 Score = 63.9 bits (154),  Expect = 1e-08, Method: Compositional matrix adjust.
 Identities = 50/149 (34%), Positives = 75/149 (51%), Gaps = 4/149 (2%)

Query  15   ILGAAAELIALRGYSSTSTRDIAAAVGVEQPAIYKHFSAKRDILAALVRLAVEWPLELFG  74
            IL AAAEL    GY+ TSTR IA AVG+ Q ++Y HFS K DILA L+   V   +E   
Sbjct  33   ILDAAAELFTRHGYTGTSTRMIAEAVGIRQASMYHHFSTKDDILAHLLETTVVGSVEQAR  92

Query  75   HITAMPVPAVVKLHRWLTESLDHLHASPYVLVSILITPDLHQESFVAERELVAEMERALV  134
             +     PA+ +L       ++ L  + + L ++ + P++ +  FV  R    E+  A  
Sbjct  93   TLLDADGPALERLLTLARYDVEQLARARWNLGALYLLPEVGEPRFVEFRSARQELAAAYA  152

Query  135  GLIETGQGE-GDVRAMHPLSAARLVQALF  162
             L     G+  D R + P    RLV+++ 
Sbjct  153  ALTSAVLGDPADKRCLLPF---RLVESVI  178


>gi|163760735|ref|ZP_02167815.1| transcriptional regulator, TetR family protein [Hoeflea phototrophica 
DFL-43]
 gi|162282057|gb|EDQ32348.1| transcriptional regulator, TetR family protein [Hoeflea phototrophica 
DFL-43]
Length=200

 Score = 63.9 bits (154),  Expect = 1e-08, Method: Compositional matrix adjust.
 Identities = 51/169 (31%), Positives = 80/169 (48%), Gaps = 6/169 (3%)

Query  1    MPRQAGR-WSPTALRILGAAAELIALRGYSSTSTRDIAAAVGVEQPAIYKHFSAKRDILA  59
            M R+AG   + TA ++   A EL A  GY++ S R IAAA GV+  AIY HF  K+D+L 
Sbjct  1    MARRAGSSGAETAEKLRNVALELFAQSGYAAVSMRAIAAATGVQAGAIYNHFPTKQDLLN  60

Query  60   ALVRLAVEWPLELFGHITA---MPVPAVVKLHRWLTESLDHLHASPYVLVSILITPDLHQ  116
             L+++ +E  L           MP  A+ +  R+      HL  S  V +S +   +L  
Sbjct  61   ELLQVHMETLLASCAEAEQPGLMPPDALEEFVRFHIRY--HLDRSREVFISYMELRNLEG  118

Query  117  ESFVAERELVAEMERALVGLIETGQGEGDVRAMHPLSAARLVQALFDAL  165
            E+F     L  + ER    ++E G  +G    + P      + A+ + +
Sbjct  119  ENFNEIERLRRQYERVPYAILERGAADGSFSIIDPQVTTMAIIAMLNGM  167


>gi|194016628|ref|ZP_03055242.1| TetR family transcriptional regulator [Bacillus pumilus ATCC 
7061]
 gi|194012101|gb|EDW21669.1| TetR family transcriptional regulator [Bacillus pumilus ATCC 
7061]
Length=216

 Score = 63.9 bits (154),  Expect = 1e-08, Method: Compositional matrix adjust.
 Identities = 42/157 (27%), Positives = 77/157 (50%), Gaps = 11/157 (7%)

Query  15   ILGAAAELIALRGYSSTSTRDIAAAVGVEQPAIYKHFSAKRDILAALVRLAVEWPLELFG  74
            IL AA EL + +GY  T+  DI  AVG+ +   Y +FS+K +++ A++   ++  + +  
Sbjct  14   ILNAAEELFSTKGYQQTTIIDILKAVGIAKGTFYYYFSSKEEVMDAIIDRIIKADIIVAK  73

Query  75   HITAMP-VPAVVKLHRWLTESLDHLHASPYVLVSILITP---DLHQESFVAERELVAEME  130
             I A P +P V KL R +        ++   ++     P   ++HQ+S +   + + E+ 
Sbjct  74   RIAAEPDLPVVDKLFRIIMAQSPQQGSNKQGMIEQFHQPSNAEMHQKSLI---KAIKELS  130

Query  131  RALVGLIETGQGEGDVRAMHPLSAARLV----QALFD  163
              L  +I+ G GEG  +  +P      +    Q +FD
Sbjct  131  PVLADVIQQGVGEGTFKTKYPQETVEFLLASAQVIFD  167


>gi|333918744|ref|YP_004492325.1| transcription regulator AmtR [Amycolicicoccus subflavus DQS3-9A1]
 gi|333480965|gb|AEF39525.1| Transcription regulator AmtR [Amycolicicoccus subflavus DQS3-9A1]
Length=234

 Score = 63.9 bits (154),  Expect = 2e-08, Method: Compositional matrix adjust.
 Identities = 50/136 (37%), Positives = 66/136 (49%), Gaps = 6/136 (4%)

Query  2    PRQAGRWSPTAL---RILGAAAELIALRGYSSTSTRDIAAAVGVEQPAIYKHFSAKRDIL  58
            PR A R  P       IL AAAEL    GY+STSTR IA AVGV Q  IY +F  K DIL
Sbjct  10   PRSAQRRRPGETAREEILDAAAELFTTHGYASTSTRKIAEAVGVRQATIYHYFGTKDDIL  69

Query  59   AALVRLAVEWPLELFGHITAMPVPAVVKLHRWLTESLDHLHASPYVLVSILITPDLHQES  118
             AL+   V   L+    + A       +LH         L  S + + ++ + P+L  E 
Sbjct  70   EALLSGTVSHTLDAAFALHATTGDPAARLHSLAWYDGIQLWNSHWNIGALYLLPELRAER  129

Query  119  ---FVAERELVAEMER  131
               FVA R+ + ++ R
Sbjct  130  FAPFVASRDELRQVYR  145


>gi|227820121|ref|YP_002824092.1| TetR family transcriptional regulator [Sinorhizobium fredii NGR234]
 gi|227339120|gb|ACP23339.1| putative transcriptional regulator protein, TetR family [Sinorhizobium 
fredii NGR234]
Length=202

 Score = 63.5 bits (153),  Expect = 2e-08, Method: Compositional matrix adjust.
 Identities = 59/189 (32%), Positives = 85/189 (45%), Gaps = 24/189 (12%)

Query  14   RILGAAAELIALRGYSSTSTRDIAAAVGVEQPAIYKHFSAKRDILAALVRLAVEWPLELF  73
            RIL +A  L    GY+ T+  DIA  +G+    IY+ FS+K +I  AL    +E   +  
Sbjct  19   RILESAERLFRHYGYTKTNVADIARDLGMSPANIYRFFSSKTEIHQALCARMLEASYQQA  78

Query  74   GHITAMPVPA-------VVKLHRWLTES-LDHLHASPYVLVSILITPDLHQESFVAEREL  125
              I  +P+ A       V+  HR   E+ LD       V+V+I       QE  V E+ L
Sbjct  79   YEIARLPLSAPERLRRYVLAQHRMTVETMLDEQKVHEMVVVAI------EQEWHVIEKHL  132

Query  126  VAEMERALVGLIETGQGEGDVRAMHPLSAARLVQALFDALALPEFAV---------SPDE  176
               ++R L G+I  G   G+     P  AAR   A    L  P+            +PDE
Sbjct  133  -DRIDRLLAGIIREGIEAGEFAEQDPEIAARCFGASIVTLCHPQIVAQCLAKENRPTPDE  191

Query  177  IVEFAMTAL  185
            ++EFA+ AL
Sbjct  192  LIEFAVRAL  200


>gi|29833243|ref|NP_827877.1| TetR family transcriptional regulator [Streptomyces avermitilis 
MA-4680]
 gi|29610365|dbj|BAC74412.1| putative TetR-family transcriptional regulator [Streptomyces 
avermitilis MA-4680]
Length=207

 Score = 63.2 bits (152),  Expect = 3e-08, Method: Compositional matrix adjust.
 Identities = 39/117 (34%), Positives = 63/117 (54%), Gaps = 1/117 (0%)

Query  15   ILGAAAELIALRGYSSTSTRDIAAAVGVEQPAIYKHFSAKRDILAALVRLAVEWPLELFG  74
            +L AAAEL   RGY++T+TR +A   G+ Q ++Y + S K ++LAAL+   V   L L  
Sbjct  27   LLTAAAELFTTRGYAATTTRAVAERAGMRQASMYHYVSGKEELLAALLESTVTPSLALAR  86

Query  75   HITAM-PVPAVVKLHRWLTESLDHLHASPYVLVSILITPDLHQESFVAERELVAEME  130
            H+ A    PA  +L       ++ L   P+ L  + + P++H E F     + AE++
Sbjct  87   HLLAEDAAPAESRLWELCRTDVELLCGGPHNLGGLYLLPEVHTERFAGFHAVRAELK  143


>gi|257791035|ref|YP_003181641.1| TetR family transcriptional regulator [Eggerthella lenta DSM 
2243]
 gi|317488249|ref|ZP_07946816.1| tetR family Bacterial regulatory protein [Eggerthella sp. 1_3_56FAA]
 gi|257474932|gb|ACV55252.1| transcriptional regulator, TetR family [Eggerthella lenta DSM 
2243]
 gi|316912631|gb|EFV34173.1| tetR family Bacterial regulatory protein [Eggerthella sp. 1_3_56FAA]
Length=212

 Score = 61.6 bits (148),  Expect = 7e-08, Method: Compositional matrix adjust.
 Identities = 37/109 (34%), Positives = 54/109 (50%), Gaps = 10/109 (9%)

Query  7    RWSPTALRILGAAAELIALRGYSSTSTRDIAAAVGVEQPAIYKHFSAKRDILAALVRLAV  66
            R   T  RI+  A  L A RG+ + S RDIAAAVG++  ++Y HFS K+ I  A+VR A+
Sbjct  2    RGKDTKERIVEEAFALFASRGFHAVSVRDIAAAVGIKDASLYNHFSGKQAIFDAIVRDAL  61

Query  67   EWPLELFGHIT--------AMPVPAVV--KLHRWLTESLDHLHASPYVL  105
            E     FG           A P   +   ++H  +  S  +    PY++
Sbjct  62   ERTRRFFGERNILFDVSDDATPYEEMNAERMHEMVLPSFRYFFEDPYMV  110


>gi|325830706|ref|ZP_08164090.1| transcriptional regulator, TetR family [Eggerthella sp. HGA1]
 gi|325487113|gb|EGC89556.1| transcriptional regulator, TetR family [Eggerthella sp. HGA1]
Length=212

 Score = 61.6 bits (148),  Expect = 8e-08, Method: Compositional matrix adjust.
 Identities = 37/109 (34%), Positives = 55/109 (51%), Gaps = 10/109 (9%)

Query  7    RWSPTALRILGAAAELIALRGYSSTSTRDIAAAVGVEQPAIYKHFSAKRDILAALVRLAV  66
            R   T  RI+  A  L A RG+ + S RDIAAAVG++  ++Y HFS K+ I  A+VR A+
Sbjct  2    RGKDTKERIVEEAFALFASRGFHAVSVRDIAAAVGIKDASLYNHFSGKQAIFDAIVRDAL  61

Query  67   EWPLELFGHIT--------AMPVPAVV--KLHRWLTESLDHLHASPYVL  105
            E     FG  +        A P   +   ++H  +  S  +    PY++
Sbjct  62   ERTRRFFGERSILFDVSDDATPYEEMNAERIHEMVLPSFRYFFEDPYMV  110


>gi|311900046|dbj|BAJ32454.1| putative TetR family transcriptional regulator [Kitasatospora 
setae KM-6054]
Length=235

 Score = 61.6 bits (148),  Expect = 8e-08, Method: Compositional matrix adjust.
 Identities = 43/125 (35%), Positives = 63/125 (51%), Gaps = 1/125 (0%)

Query  15   ILGAAAELIALRGYSSTSTRDIAAAVGVEQPAIYKHFSAKRDILAALVRLAVEWPLELFG  74
            +L AAAEL    GY++T+TR +A   G+ Q ++Y +F+ K DILA L+   VE  L L G
Sbjct  31   VLAAAAELFTENGYAATTTRAVAEKAGLRQASMYHYFARKEDILATLLESTVEPSLLLAG  90

Query  75   HITAMP-VPAVVKLHRWLTESLDHLHASPYVLVSILITPDLHQESFVAERELVAEMERAL  133
             + A P +    +L          LH   Y L ++   P++  E F   R   AE+  A 
Sbjct  91   TLLARPGLDPAARLWTLAAADAALLHRGLYNLGALYQLPEVRGERFARFRGARAELRSAY  150

Query  134  VGLIE  138
              L+E
Sbjct  151  GALLE  155


>gi|108798810|ref|YP_639007.1| TetR family transcriptional regulator [Mycobacterium sp. MCS]
 gi|119867927|ref|YP_937879.1| TetR family transcriptional regulator [Mycobacterium sp. KMS]
 gi|126434411|ref|YP_001070102.1| TetR family transcriptional regulator [Mycobacterium sp. JLS]
 gi|108769229|gb|ABG07951.1| transcriptional regulator, TetR family [Mycobacterium sp. MCS]
 gi|119694016|gb|ABL91089.1| transcriptional regulator, TetR family [Mycobacterium sp. KMS]
 gi|126234211|gb|ABN97611.1| transcriptional regulator, TetR family [Mycobacterium sp. JLS]
Length=226

 Score = 61.2 bits (147),  Expect = 1e-07, Method: Compositional matrix adjust.
 Identities = 54/159 (34%), Positives = 77/159 (49%), Gaps = 8/159 (5%)

Query  15   ILGAAAELIALRGYSSTSTRDIAAAVGVEQPAIYKHFSAKRDILAALVRLAVEWPLELF-  73
            IL AA EL    GY+STSTR IA  VG+ Q ++Y +F  K DIL AL+   V   L    
Sbjct  25   ILDAAGELFTTLGYASTSTRHIAELVGIRQASLYHYFRTKDDILCALLSQTVSPTLGFIP  84

Query  74   GHITAMP-VPAVVKLHRWLTESLDHLHASPYVLVSILITPDLHQ---ESFVAERELVAEM  129
              + A P + A   LH   T   D L + P+ L ++ + P+L     E F ++RE +   
Sbjct  85   SLLGAQPALTAAEHLHALATFDGDQLLSGPWNLGALYLLPELRDARLEPFWSDRERLRLH  144

Query  130  ERALVGLIETGQGEGDVRAMHPLSAARLVQALFDALALP  168
              AL   +    G  +  A  P    RLV++L +  + P
Sbjct  145  YLALSRAVVEQTGVHEAAADLPF---RLVESLVNMWSTP  180


>gi|296139307|ref|YP_003646550.1| TetR family transcriptional regulator [Tsukamurella paurometabola 
DSM 20162]
 gi|296027441|gb|ADG78211.1| transcriptional regulator, TetR family [Tsukamurella paurometabola 
DSM 20162]
Length=231

 Score = 60.5 bits (145),  Expect = 1e-07, Method: Compositional matrix adjust.
 Identities = 55/161 (35%), Positives = 82/161 (51%), Gaps = 6/161 (3%)

Query  2    PRQAGRWSPTALRILGAAAELIALRGYSSTSTRDIAAAVGVEQPAIYKHFSAKRDILAAL  61
            PR+ G  +  A  IL AAAEL   RGY+ TSTR IA AVG+ Q ++Y HFS K +IL AL
Sbjct  22   PRRPG--ATAADEILDAAAELFTSRGYAGTSTRAIAEAVGIRQASLYHHFSTKDEILTAL  79

Query  62   VRLAVEWPLELFGHITAMPVPAVVKLHRWLTESLDHLHASPYVLVSILITPDLHQESFVA  121
            +   V+ PL L   + A     + +L +      + L  + + L ++   P+L  ++F  
Sbjct  80   LEATVQAPLALARQLAAADGEPIDRLVQLAAFDAEQLATARFNLGALYHLPELAGDAFAE  139

Query  122  ERELVAEMERALVGLIETGQGEGDV-RAMHPLSAARLVQAL  161
             R   AE+      L     G+ D  R + P    RLV+++
Sbjct  140  FRRDRAELAEHYRSLSAAAIGDKDDPRTLLPF---RLVESV  177


>gi|118468120|ref|YP_885944.1| TetR family transcriptional regulator [Mycobacterium smegmatis 
str. MC2 155]
 gi|118169407|gb|ABK70303.1| transcriptional regulator, TetR family protein [Mycobacterium 
smegmatis str. MC2 155]
Length=207

 Score = 60.1 bits (144),  Expect = 2e-07, Method: Compositional matrix adjust.
 Identities = 56/190 (30%), Positives = 81/190 (43%), Gaps = 25/190 (13%)

Query  3    RQAGRWS-PTALRILGAAAELIALRGYSSTSTRDIAAAVGVEQPAIYKHFSAKRDILAAL  61
            R AG  S  T  R++ AA    A  GY   +   IA   GV   ++Y HF  K  +  A+
Sbjct  13   RPAGTDSVDTRQRVIDAACRCFAQFGYGPATNNQIAEMAGVTAGSVYYHFGTKNKLFEAV  72

Query  62   VRLAVEWPLELFGHITAMPVPAVVKLHR-------WLTESLDHLHASPYVLVSILITP-D  113
                     +++G I    + AV   H         LTES+   H SP +   +   P D
Sbjct  73   CD-------DVYGKILTRVMLAVSGSHSVVGLLRAVLTESMRINHESPELAGFVATAPID  125

Query  114  LHQ-----ESFVAERELVAEMERALVGLIETGQGEGDVRA-MHPLSAARLVQALFDALAL  167
              +     ESF  +    A M  AL   + +GQ  GD+ A + P+  ARL+ A+ D  A 
Sbjct  126  ARRHRELAESFATQG---ARMADALTDAVRSGQDAGDIAADLDPVRVARLISAVVDGFAH  182

Query  168  PEFAVSPDEI  177
               +  PDE+
Sbjct  183  AAVSADPDEM  192


>gi|229494137|ref|ZP_04387900.1| transcriptional regulator, TetR family [Rhodococcus erythropolis 
SK121]
 gi|229318499|gb|EEN84357.1| transcriptional regulator, TetR family [Rhodococcus erythropolis 
SK121]
Length=211

 Score = 60.1 bits (144),  Expect = 2e-07, Method: Compositional matrix adjust.
 Identities = 56/194 (29%), Positives = 87/194 (45%), Gaps = 21/194 (10%)

Query  14   RILGAAAELIALRGYSSTSTRDIAAAVGVEQPAIYKHFSAKRDILAALVRLAVEWPLELF  73
            +IL  AA+   + GY STS  DI +A  + + A+Y HFS+K ++  A++    +  +  F
Sbjct  11   QILQGAADRFEVTGYGSTSMNDIVSAAQMTKGAVYFHFSSKDELAQAVIEEQHQISISAF  70

Query  74   GHITAMPVPAVVKLHRWLTESLDHLHASPYVLVSILIT-----PDLHQESFVAERELVAE  128
              + A   PA+ +L     E    L A P V   I +T     PD  Q  +VA       
Sbjct  71   TAVAATGAPALEQLVMVCHEMGRQLVAEPIVRAGIRLTLELASPDGSQGPYVA-------  123

Query  129  MERALVGLIETGQGEGDVR-AMHPLSAARLVQALFDALALPEFAVSP--------DEIVE  179
              R L  L E  + EGD+R  + P S  R+V + F  + L    ++         DE+  
Sbjct  124  WIRELRKLAEAAKLEGDIRDDVEPESVGRVVISAFTGVQLVSNVLTRRSDLNDRIDELFT  183

Query  180  FAMTALLSDPDRLA  193
              +  ++SD  R A
Sbjct  184  LLLAGVVSDKRRSA  197


>gi|84501810|ref|ZP_00999968.1| transcriptional regulator, TetR family protein [Oceanicola batsensis 
HTCC2597]
 gi|84389805|gb|EAQ02439.1| transcriptional regulator, TetR family protein [Oceanicola batsensis 
HTCC2597]
Length=212

 Score = 60.1 bits (144),  Expect = 2e-07, Method: Compositional matrix adjust.
 Identities = 33/132 (25%), Positives = 67/132 (51%), Gaps = 5/132 (3%)

Query  14   RILGAAAELIALRGYSSTSTRDIAAAVGVEQPAIYKHFSAKRDILAALVRLAVEWPLELF  73
            RIL  AAEL + +GYS  S  ++A  +GV +P IY +   K+DIL  +    ++ P  + 
Sbjct  23   RILSTAAELFSQKGYSGASVSELANMIGVTKPFIYYYTKNKQDILEQICIATIDLPHLVM  82

Query  74   GHITAMPVPAVVKLHRWL-----TESLDHLHASPYVLVSILITPDLHQESFVAERELVAE  128
              + +  + A V L++++      +  +  + S +    + ++P++ +      ++  A 
Sbjct  83   NEVFSEDLSATVSLYKFVRRFAWVQGQNQNYVSVFFREELNLSPEVSRYVLAQRKKFDAR  142

Query  129  MERALVGLIETG  140
            +E  L+  +ETG
Sbjct  143  LEELLLKGVETG  154


>gi|288922880|ref|ZP_06417043.1| transcriptional regulator, TetR family [Frankia sp. EUN1f]
 gi|288345771|gb|EFC80137.1| transcriptional regulator, TetR family [Frankia sp. EUN1f]
Length=226

 Score = 60.1 bits (144),  Expect = 2e-07, Method: Compositional matrix adjust.
 Identities = 43/140 (31%), Positives = 66/140 (48%), Gaps = 12/140 (8%)

Query  15   ILGAAAELIALRGYSSTSTRDIAAAVGVEQPAIYKHFSAKRDILAALVRLAVEWPLELFG  74
            IL  AAEL A RG+  T+ RDI    G+   ++Y HF +K  +LA ++R  +E     F 
Sbjct  27   ILAIAAELFATRGFPQTTVRDIGDEAGILSGSLYHHFDSKEAMLAEILRDFMENLRARFA  86

Query  75   HITAMPVPAVVKLHRWLTESLDHLHASPYVLV-------SILITPDLHQESFVAERELVA  127
             + A   P   +L   +  S   +H  P+ +        ++   P+     FV +  L  
Sbjct  87   EVVAQDRPPRARLDELVRGSFATIHQQPHAVALYQKESGALAGVPEFR---FVGQISL--  141

Query  128  EMERALVGLIETGQGEGDVR  147
            E+E+  VG+I  GQ  GD R
Sbjct  142  EIEKMWVGVIVAGQQVGDFR  161


>gi|271968981|ref|YP_003343177.1| TetR family transcriptional regulator [Streptosporangium roseum 
DSM 43021]
 gi|270512156|gb|ACZ90434.1| putative transcriptional regulator, TetR family [Streptosporangium 
roseum DSM 43021]
Length=194

 Score = 60.1 bits (144),  Expect = 2e-07, Method: Compositional matrix adjust.
 Identities = 48/147 (33%), Positives = 72/147 (49%), Gaps = 9/147 (6%)

Query  10   PTALRILGAAAELIALRGYSSTSTRDIAAAVGVEQPAIYKHFSAKRDILAALVRLAVEWP  69
            P   R++G A  L A RG+ STS ++I AA GV + A+Y +F +K D+L  +    +   
Sbjct  7    PVRQRLIGEATRLFAERGFESTSVQEIVAAAGVTKGAMYHYFDSKDDLLHEIYGRVLRMQ  66

Query  70   LELFGHITAMPVPAVVKLHRWLTE----SLDHLHASPYVLVSI-LITPDLHQESFVAERE  124
            +E    +   P P   +LH    +    ++++L  S     S+ L+ PD  ++S  AER 
Sbjct  67   MERLTLLADGPGPVAERLHAAAADVVLTTVENLDDSKIFFRSMHLLAPDT-RKSVRAERR  125

Query  125  LVAEMERALVGLIETGQGEGDVRAMHP  151
               E  R LV     GQ EG  RA  P
Sbjct  126  RYHERFRDLV---TEGQREGVFRADTP  149


>gi|295695869|ref|YP_003589107.1| TetR family transcriptional regulator [Bacillus tusciae DSM 2912]
 gi|295411471|gb|ADG05963.1| transcriptional regulator, TetR family [Bacillus tusciae DSM 
2912]
Length=192

 Score = 60.1 bits (144),  Expect = 2e-07, Method: Compositional matrix adjust.
 Identities = 57/181 (32%), Positives = 80/181 (45%), Gaps = 26/181 (14%)

Query  14   RILGAAAELIALRGYSSTSTRDIAAAVGVEQPAIYKHFSAKRDILAALVRLAVEWPLELF  73
            +IL A+  L + +GY  T+ RDIA A G+   ++Y H  +K D+L  +V    +  L   
Sbjct  9    QILAASERLFSEKGYHGTTIRDIAEASGILSGSLYAHIDSKEDLLFEIVNQGADNFLGAL  68

Query  74   GHITAMPVPAVVKLHRWLTESL----DHLHASPYVLVSILITPDLHQESFVAERELVAEM  129
              I A P     KL R L   +    +HLHA+   L       D         R+++ E 
Sbjct  69   EPIVASPGNPEEKLRRGLAAHIRVVGEHLHAAKVFLHDWRALSD-------ERRQIILEK  121

Query  130  ER---ALVG-LIETGQGEGDVRAMHP-------LSAARLVQALFDALALPEFAVSPDEIV  178
             R   AL G L+E G   G  R +HP       LS A  V   +D    PE  + PDEI 
Sbjct  122  RRRYEALWGALLEEGIQAGVFRPVHPKFAQLVILSVANWVYQWYD----PEGPLGPDEIA  177

Query  179  E  179
            +
Sbjct  178  D  178


>gi|163854670|ref|YP_001628968.1| TetR family transcriptional regulator [Bordetella petrii DSM 
12804]
 gi|163258398|emb|CAP40697.1| transcriptional regulator, TetR-family [Bordetella petrii]
Length=220

 Score = 59.3 bits (142),  Expect = 3e-07, Method: Compositional matrix adjust.
 Identities = 48/164 (30%), Positives = 80/164 (49%), Gaps = 21/164 (12%)

Query  14   RILGAAAELIALRGYSSTSTRDIAAAVGVEQPAIYKHFSAKRDILAALVRLAVEWPLELF  73
            RIL  AA L A  GY ++S  D+AAA+GV + AIY +++ K+DI  A++       LE+ 
Sbjct  39   RILEEAARLFARSGYENSSVADLAAALGVSKAAIYHYYTTKQDIYDAII-------LEVV  91

Query  74   GHITAMPVPAVV-------KLHRWLTESLDHLHASPYVLVSILITPDLHQESFVAERELV  126
            G +T     AV        +L +++     +        V++L+    +    + ER+  
Sbjct  92   GGLTVAVSQAVAQADTASGRLRQFMLAHARYFEEHHPEFVTMLVG---YSGMAIPERDDA  148

Query  127  AEM----ERALVGLIETGQGEGDVRAMHPLSAARLVQALFDALA  166
            A +    ER L G++  G   G+ RAM   S  R V ++ + +A
Sbjct  149  ARLRDGYERMLRGILADGMASGEFRAMDVASTGRAVLSMLNWMA  192


>gi|300784545|ref|YP_003764836.1| TetR family transcriptional regulator [Amycolatopsis mediterranei 
U32]
 gi|208969091|dbj|BAG74314.1| gamma-butyrolactone autoregulator receptor [Amycolatopsis mediterranei]
 gi|299794059|gb|ADJ44434.1| TetR family transcriptional regulator [Amycolatopsis mediterranei 
U32]
Length=221

 Score = 59.3 bits (142),  Expect = 4e-07, Method: Compositional matrix adjust.
 Identities = 42/123 (35%), Positives = 63/123 (52%), Gaps = 0/123 (0%)

Query  15   ILGAAAELIALRGYSSTSTRDIAAAVGVEQPAIYKHFSAKRDILAALVRLAVEWPLELFG  74
            +L AA EL    GY++T+TR IA   G+ Q ++Y HF AK DILAAL+   V   L L  
Sbjct  26   VLEAAGELFTGAGYAATTTRAIAERAGLRQASLYYHFPAKEDILAALLAETVRPSLALAA  85

Query  75   HITAMPVPAVVKLHRWLTESLDHLHASPYVLVSILITPDLHQESFVAERELVAEMERALV  134
             + A   PA V+L       +  L  + + L ++ + P++   S    R   AE++ A  
Sbjct  86   RLVAGEAPAAVRLWALAYADIGLLGGARHNLGALYLLPEVGSPSLARFRIERAELKAAYG  145

Query  135  GLI  137
             L+
Sbjct  146  RLV  148


>gi|145225177|ref|YP_001135855.1| TetR family transcriptional regulator [Mycobacterium gilvum PYR-GCK]
 gi|145217663|gb|ABP47067.1| transcriptional regulator, TetR family [Mycobacterium gilvum 
PYR-GCK]
Length=220

 Score = 59.3 bits (142),  Expect = 4e-07, Method: Compositional matrix adjust.
 Identities = 31/58 (54%), Positives = 39/58 (68%), Gaps = 0/58 (0%)

Query  14  RILGAAAELIALRGYSSTSTRDIAAAVGVEQPAIYKHFSAKRDILAALVRLAVEWPLE  71
           RIL +A ELIA RGY + S  DI  A GV  PAIY+HF++K D+LAAL    V+  L+
Sbjct  19  RILASATELIAERGYHAVSMADIGVASGVVGPAIYRHFNSKSDLLAALFERVVDKLLK  76


>gi|300767812|ref|ZP_07077722.1| transcription regulator [Lactobacillus plantarum subsp. plantarum 
ATCC 14917]
 gi|300494797|gb|EFK29955.1| transcription regulator [Lactobacillus plantarum subsp. plantarum 
ATCC 14917]
Length=200

 Score = 59.3 bits (142),  Expect = 4e-07, Method: Compositional matrix adjust.
 Identities = 29/62 (47%), Positives = 38/62 (62%), Gaps = 0/62 (0%)

Query  1   MPRQAGRWSPTALRILGAAAELIALRGYSSTSTRDIAAAVGVEQPAIYKHFSAKRDILAA  60
           M  +A + + T   ILG A EL    GY +TSTRDIA A+G+ QPA+Y HF  K  I  A
Sbjct  1   MATRAEQMAKTHQAILGTARELFLRNGYDATSTRDIANAIGITQPALYHHFKDKEVIFLA  60

Query  61  LV  62
           ++
Sbjct  61  VI  62


>gi|154247994|ref|YP_001418952.1| TetR family transcriptional regulator [Xanthobacter autotrophicus 
Py2]
 gi|154162079|gb|ABS69295.1| transcriptional regulator, TetR family [Xanthobacter autotrophicus 
Py2]
Length=223

 Score = 58.5 bits (140),  Expect = 5e-07, Method: Compositional matrix adjust.
 Identities = 48/168 (29%), Positives = 82/168 (49%), Gaps = 7/168 (4%)

Query  15   ILGAAAELIALRGYSSTSTRDIAAAVGVEQPAIYKHFSAKRDILAALVRLAVEWPLELFG  74
            +L AAA L   +G+ +TS  D+A  + V +P +Y +F +K D+L    R+ +E       
Sbjct  34   VLKAAARLFNEKGFHATSLDDVARQLNVTKPTLYHYFRSKDDVLFECCRMGLEMIEAAAA  93

Query  75   HITAMPVPAVVKLHRWLTESLDHLHASPYVLVSILITPD--LHQESFVAERELVAEMERA  132
             +       + +L R L E         + + SI  TPD  L  E+    R L A+++RA
Sbjct  94   TVPGSQASGLERL-RALMEQYAEAMTMDFGM-SISRTPDTALSPENRAELRRLKAQIDRA  151

Query  133  LVGLIETGQGEGDVRAMHPLSAARLVQALFDALA---LPEFAVSPDEI  177
            L G+I++G  +G +      +AA  +    +A+A    P+  ++P EI
Sbjct  152  LRGVIQSGIEDGSIAPCDVRTAAFAIAGALNAIAHWYKPDGPLAPAEI  199


>gi|229017860|ref|ZP_04174743.1| Transcriptional regulator, TetR [Bacillus cereus AH1273]
 gi|229024063|ref|ZP_04180537.1| Transcriptional regulator, TetR [Bacillus cereus AH1272]
 gi|228737241|gb|EEL87762.1| Transcriptional regulator, TetR [Bacillus cereus AH1272]
 gi|228743451|gb|EEL93568.1| Transcriptional regulator, TetR [Bacillus cereus AH1273]
Length=217

 Score = 58.5 bits (140),  Expect = 5e-07, Method: Compositional matrix adjust.
 Identities = 48/176 (28%), Positives = 84/176 (48%), Gaps = 16/176 (9%)

Query  13   LRILGAAAELIALRGYSSTSTRDIAAAVGVEQPAIYKHFSAKRDILAALV-----RLAVE  67
            +RIL AA ++   +GY+STST +IA   GV +  I++++  K+D+L A+V     + A  
Sbjct  23   MRILEAAVDMFGEKGYASTSTSEIAKRAGVAEGTIFRYYKTKKDLLFAVVMPTLTKFAAP  82

Query  68   WPLELFG-HITAMPVPAVVKLHRWLTESLDHLHASPYVLVSILI-----TPDLHQE-SFV  120
            + ++ F   I      +   L R +  +        + ++ ILI      P+L  E   +
Sbjct  83   FFIQAFAKEIFKKDYKSYEGLLRVVIHNRFEFAKKHFPMIKILIQEVPFQPELKSEIQQL  142

Query  121  AERELVAEMERALVGLIETGQGEGDVRAMHPLSAARLVQALFDALALPEFAVSPDE  176
             E EL++  ++ +V      Q EG++  M P S  RL  +      L  F + P+E
Sbjct  143  VETELLSHFKKLIVKF----QEEGEIIEMPPSSVLRLTLSAVLGFLLTRFLLLPEE  194


>gi|229076815|ref|ZP_04209725.1| Transcriptional regulator, TetR [Bacillus cereus Rock4-18]
 gi|228706304|gb|EEL58567.1| Transcriptional regulator, TetR [Bacillus cereus Rock4-18]
Length=217

 Score = 58.5 bits (140),  Expect = 6e-07, Method: Compositional matrix adjust.
 Identities = 48/176 (28%), Positives = 85/176 (49%), Gaps = 16/176 (9%)

Query  13   LRILGAAAELIALRGYSSTSTRDIAAAVGVEQPAIYKHFSAKRDILAALV-----RLAVE  67
            +RIL AA ++   +GY+STST +IA   GV +  I++++  K+D+L A+V     + A  
Sbjct  23   MRILEAAVDMFGEKGYASTSTSEIAKRAGVAEGTIFRYYKTKKDLLLAVVMPTLTKFAAP  82

Query  68   WPLELFG-HITAMPVPAVVKLHRWLTESLDHLHASPYVLVSILI-----TPDLHQE-SFV  120
            + ++ F   I      +  +L R +  +        + ++ ILI      P+L  E   +
Sbjct  83   FFVQAFAKEIFKTDYESYEELLRVVIHNRFEFAKKHFPMIKILIQEVPFQPELKSEIQQL  142

Query  121  AERELVAEMERALVGLIETGQGEGDVRAMHPLSAARLVQALFDALALPEFAVSPDE  176
             E EL++  ++ +V      Q EG++  M P S  RL  +      L  F + P+E
Sbjct  143  VETELLSHFKKLIVKF----QEEGEIIEMPPPSVLRLTLSAVLGFLLTRFLLLPEE  194


>gi|300781697|ref|ZP_07091551.1| transcription regulator AmtR [Corynebacterium genitalium ATCC 
33030]
 gi|300533404|gb|EFK54465.1| transcription regulator AmtR [Corynebacterium genitalium ATCC 
33030]
Length=220

 Score = 58.5 bits (140),  Expect = 6e-07, Method: Compositional matrix adjust.
 Identities = 43/129 (34%), Positives = 66/129 (52%), Gaps = 2/129 (1%)

Query  2    PRQAGRWSPTALRILGAAAELIALRGYSSTSTRDIAAAVGVEQPAIYKHFSAKRDILAAL  61
            PR++GR +     IL A+AEL   +G+++TST +IA AVGV Q ++Y HF +K DI   L
Sbjct  13   PRRSGRTARE--EILDASAELFTKQGFATTSTHEIADAVGVRQASLYYHFPSKADIFLTL  70

Query  62   VRLAVEWPLELFGHITAMPVPAVVKLHRWLTESLDHLHASPYVLVSILITPDLHQESFVA  121
            ++  +E  L L   +      A  KL   +      L +S + +  +   P    E FV 
Sbjct  71   LKSTIEPSLALGAVLRDSDASANQKLWALVAAQTRLLLSSKWNIGRLYQLPVATSEEFVE  130

Query  122  ERELVAEME  130
              +  AE+E
Sbjct  131  YHKERAELE  139


>gi|209526291|ref|ZP_03274820.1| transcriptional regulator, TetR family [Arthrospira maxima CS-328]
 gi|209493220|gb|EDZ93546.1| transcriptional regulator, TetR family [Arthrospira maxima CS-328]
Length=208

 Score = 58.5 bits (140),  Expect = 6e-07, Method: Compositional matrix adjust.
 Identities = 49/179 (28%), Positives = 87/179 (49%), Gaps = 17/179 (9%)

Query  14   RILGAAAELIALRGYSSTSTRDIAAAVGVEQPAIYKHFSAKRDILAALVRLA-VEWPLEL  72
            RIL AA +L A RGY +T+ +D+AA VGV +  I+++F  K+ IL  +V    VE   +L
Sbjct  17   RILKAATKLFARRGYEATTIKDLAAKVGVAEGTIFRYFPNKKAILVEVVTQGWVEILTDL  76

Query  73   FGHITAMPVPAVVKLHRWLTESLDH----LHASPYVLVSILITPDLHQE-SFVAERELVA  127
               ++       V  ++ +++ + H    LH++  +L    +    H E S   + E++A
Sbjct  77   LTELSE------VANYQGISQIMRHRMMGLHSNADLLRVCFLEAQFHPELSDRIQSEIIA  130

Query  128  EMERALVGLIETGQGEGDVRAMHPLSAARLVQALFDALALP-----EFAVSPDEIVEFA  181
            +M        +T   +G  R M+P   A++   +F           + A SP+++ E A
Sbjct  131  KMTDVAEAFFQTAIEKGVYRPMNPRIVAQVFLGMFAVAGFSYRTIIDPAASPNDMQEMA  189


>gi|311895237|dbj|BAJ27645.1| putative TetR family transcriptional regulator [Kitasatospora 
setae KM-6054]
Length=210

 Score = 58.5 bits (140),  Expect = 7e-07, Method: Compositional matrix adjust.
 Identities = 47/132 (36%), Positives = 66/132 (50%), Gaps = 5/132 (3%)

Query  6    GRWSPTALRILGAAAELIALRGYSSTSTRDIAAAVGVEQPAIYKHFSAKRDILAALVRLA  65
            G  +  A R+L AA +  A RGY +T+TRDIA A G+   A+Y H+ +K  +LA + R  
Sbjct  14   GERTEAARRLLLAAVDSFARRGYHATTTRDIATAAGMSPAALYIHYPSKAALLAEISRTG  73

Query  66   VEWPLELFGHITAMPVPAVVKLHRWLTESLDHLHASPYVLVSILITPDLH---QESFVAE  122
                LEL     A     V ++ R L ES    HA  + L  I I  +LH   +E F A 
Sbjct  74   HRVALELVERAEAAGTDPVERM-RALAESFTAWHARGHTLGRI-INHELHALPEEDFAAV  131

Query  123  RELVAEMERALV  134
             EL   +E  ++
Sbjct  132  AELRVRIEETVL  143


>gi|119492809|ref|ZP_01623895.1| Transcriptional Regulator, TetR family protein [Lyngbya sp. PCC 
8106]
 gi|119452962|gb|EAW34134.1| Transcriptional Regulator, TetR family protein [Lyngbya sp. PCC 
8106]
Length=207

 Score = 58.5 bits (140),  Expect = 7e-07, Method: Compositional matrix adjust.
 Identities = 45/157 (29%), Positives = 75/157 (48%), Gaps = 6/157 (3%)

Query  9    SPTALRILGAAAELIALRGYSSTSTRDIAAAVGVEQPAIYKHFSAKRDILAALVRLA-VE  67
            + T+ RIL AA  L A +GY  T+TRD+A A GV +  I++HF  K+ IL  +     +E
Sbjct  12   TETSARILKAAQRLFAHKGYDGTTTRDLAQAAGVAEGTIFRHFPNKKAILIEVATEGWIE  71

Query  68   WPLELFGHITAM-PVPAVVKLHRWLTESLDHLHASPYVLVSILITPDLHQE-SFVAEREL  125
               +L   ++ M    AV ++ R     +  LH +  ++    +    H E     + E+
Sbjct  72   ILTDLLTELSEMGSYKAVAQVMR---RRMLSLHENTDLMRVCFLEAQFHPELRDRIQSEV  128

Query  126  VAEMERALVGLIETGQGEGDVRAMHPLSAARLVQALF  162
            +A+M        ET   +G  R M+P   A++   +F
Sbjct  129  IAKMTDVAEAFFETAMEKGAYRPMNPRIVAQVFLGMF  165



Lambda     K      H
   0.321    0.134    0.387 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Effective search space used: 251148961304


  Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
    Posted date:  Sep 5, 2011  4:36 AM
  Number of letters in database: 5,219,829,388
  Number of sequences in database:  15,229,318



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40