BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv3173c Length=200 Score E Sequences producing significant alignments: (Bits) Value gi|15610309|ref|NP_217689.1| TetR/ACRR family transcriptional re... 404 4e-111 gi|344221006|gb|AEN01637.1| TetR/ACRR family transcriptional reg... 403 6e-111 gi|254233786|ref|ZP_04927111.1| hypothetical transcriptional reg... 363 9e-99 gi|339299615|gb|AEJ51725.1| TetR/ACRR family transcriptional reg... 359 1e-97 gi|289763356|ref|ZP_06522734.1| conserved hypothetical protein [... 283 1e-74 gi|254774814|ref|ZP_05216330.1| transcriptional regulator [Mycob... 241 5e-62 gi|118463334|ref|YP_881311.1| transcriptional regulator [Mycobac... 237 8e-61 gi|240168671|ref|ZP_04747330.1| transcriptional regulator [Mycob... 229 1e-58 gi|342859954|ref|ZP_08716606.1| TetR family transcriptional regu... 187 5e-46 gi|126438197|ref|YP_001073888.1| TetR family transcriptional reg... 178 3e-43 gi|108802215|ref|YP_642412.1| TetR family transcriptional regula... 176 2e-42 gi|118471079|ref|YP_886508.1| TetR family transcriptional regula... 171 6e-41 gi|331700106|ref|YP_004336345.1| regulatory protein TetR [Pseudo... 166 3e-39 gi|208969093|dbj|BAG74315.1| gamma-butyrolactone autoregulator r... 134 5e-30 gi|300787513|ref|YP_003767804.1| TetR family transcriptional reg... 134 6e-30 gi|118471278|ref|YP_890717.1| TetR family transcriptional regula... 124 5e-27 gi|300788632|ref|YP_003768923.1| TetR family transcriptional reg... 120 1e-25 gi|333990688|ref|YP_004523302.1| TetR family transcriptional reg... 115 3e-24 gi|302526692|ref|ZP_07279034.1| transcriptional regulator [Strep... 114 5e-24 gi|329934304|ref|ZP_08284383.1| tetR family transcriptional regu... 111 5e-23 gi|302556341|ref|ZP_07308683.1| transcriptional regulator [Strep... 105 3e-21 gi|111019703|ref|YP_702675.1| TetR family transcriptional regula... 104 7e-21 gi|332285539|ref|YP_004417450.1| transcriptional regulator [Pusi... 103 1e-20 gi|119964095|ref|YP_946391.1| TetR family transcriptional regula... 103 1e-20 gi|345010076|ref|YP_004812430.1| regulatory protein TetR [Strept... 102 3e-20 gi|343926505|ref|ZP_08766010.1| putative TetR family transcripti... 101 7e-20 gi|23015276|ref|ZP_00055057.1| COG1309: Transcriptional regulato... 100 1e-19 gi|334111847|ref|ZP_08486115.1| regulatory protein TetR [Methylo... 99.0 3e-19 gi|229818636|ref|YP_002880162.1| TetR family transcriptional reg... 98.2 6e-19 gi|145596506|ref|YP_001160803.1| regulatory protein TetR [Salini... 97.4 1e-18 gi|344942738|ref|ZP_08782025.1| regulatory protein TetR [Methylo... 97.4 1e-18 gi|27380233|ref|NP_771762.1| transcriptional regulator [Bradyrhi... 97.1 1e-18 gi|83311987|ref|YP_422251.1| transcriptional regulator [Magnetos... 97.1 1e-18 gi|134099989|ref|YP_001105650.1| TetR family transcriptional reg... 96.3 2e-18 gi|256824670|ref|YP_003148630.1| transcriptional regulator [Kyto... 95.1 6e-18 gi|344999087|ref|YP_004801941.1| TetR family transcriptional reg... 94.7 7e-18 gi|323527493|ref|YP_004229646.1| regulatory protein TetR [Burkho... 94.4 9e-18 gi|333986091|ref|YP_004515301.1| regulatory protein TetR [Methyl... 94.4 1e-17 gi|159038454|ref|YP_001537707.1| TetR family transcriptional reg... 94.0 1e-17 gi|256378504|ref|YP_003102164.1| TetR family transcriptional reg... 93.6 1e-17 gi|333919870|ref|YP_004493451.1| putative TetR family transcript... 93.6 1e-17 gi|345462058|ref|YP_003325974.2| TetR family transcriptional reg... 93.6 1e-17 gi|170695791|ref|ZP_02886933.1| transcriptional regulator, TetR ... 92.8 2e-17 gi|312795890|ref|YP_004028812.1| transcriptional regulator, TetR... 92.8 2e-17 gi|333919849|ref|YP_004493430.1| putative TetR family transcript... 92.8 3e-17 gi|300786039|ref|YP_003766330.1| TetR family transcriptional reg... 92.8 3e-17 gi|337746528|ref|YP_004640690.1| transcriptional regulator [Paen... 92.4 3e-17 gi|344997753|ref|YP_004800607.1| TetR family transcriptional reg... 92.4 3e-17 gi|118466289|ref|YP_880488.1| transcriptional regulator [Mycobac... 92.4 3e-17 gi|339053310|ref|ZP_08648047.1| Transcriptional regulator2C TetR... 92.0 5e-17 >gi|15610309|ref|NP_217689.1| TetR/ACRR family transcriptional regulator [Mycobacterium tuberculosis H37Rv] gi|15842750|ref|NP_337787.1| TetR family transcriptional regulator [Mycobacterium tuberculosis CDC1551] gi|31794350|ref|NP_856843.1| TetR/ACRR family transcriptional regulator [Mycobacterium bovis AF2122/97] 74 more sequence titles Length=200 Score = 404 bits (1038), Expect = 4e-111, Method: Compositional matrix adjust. Identities = 200/200 (100%), Positives = 200/200 (100%), Gaps = 0/200 (0%) Query 1 MPPVTRTTEPPRRGGRGARQRILKAAAELFYCEGINATGVELIANKASVSKRTLYQHFPS 60 MPPVTRTTEPPRRGGRGARQRILKAAAELFYCEGINATGVELIANKASVSKRTLYQHFPS Sbjct 1 MPPVTRTTEPPRRGGRGARQRILKAAAELFYCEGINATGVELIANKASVSKRTLYQHFPS 60 Query 61 KSALVEEYLRGLRQAAGEADKMPKASNATPRERLLALFDRPNRGDGRMRGCPFHNAAVEA 120 KSALVEEYLRGLRQAAGEADKMPKASNATPRERLLALFDRPNRGDGRMRGCPFHNAAVEA Sbjct 61 KSALVEEYLRGLRQAAGEADKMPKASNATPRERLLALFDRPNRGDGRMRGCPFHNAAVEA 120 Query 121 AGEMPGVERIVHSHKRDYIKGLARLAREAGAAHPRSLGNQLAVLFEGAAALSTSLDDAGP 180 AGEMPGVERIVHSHKRDYIKGLARLAREAGAAHPRSLGNQLAVLFEGAAALSTSLDDAGP Sbjct 121 AGEMPGVERIVHSHKRDYIKGLARLAREAGAAHPRSLGNQLAVLFEGAAALSTSLDDAGP 180 Query 181 WAHARAAAEVLIDQATARPV 200 WAHARAAAEVLIDQATARPV Sbjct 181 WAHARAAAEVLIDQATARPV 200 >gi|344221006|gb|AEN01637.1| TetR/ACRR family transcriptional regulator [Mycobacterium tuberculosis CTRI-2] Length=200 Score = 403 bits (1036), Expect = 6e-111, Method: Compositional matrix adjust. Identities = 199/200 (99%), Positives = 200/200 (100%), Gaps = 0/200 (0%) Query 1 MPPVTRTTEPPRRGGRGARQRILKAAAELFYCEGINATGVELIANKASVSKRTLYQHFPS 60 MPPVTRTTEPPRRGGRGARQRILKAAAELFYCEGINATGVELIANKASVSKRTLYQHFPS Sbjct 1 MPPVTRTTEPPRRGGRGARQRILKAAAELFYCEGINATGVELIANKASVSKRTLYQHFPS 60 Query 61 KSALVEEYLRGLRQAAGEADKMPKASNATPRERLLALFDRPNRGDGRMRGCPFHNAAVEA 120 KSALVEEYLRGLRQAAGEADKMPKASNATPRERLLALFDRPNRGDGRMRGCPFHNAAVEA Sbjct 61 KSALVEEYLRGLRQAAGEADKMPKASNATPRERLLALFDRPNRGDGRMRGCPFHNAAVEA 120 Query 121 AGEMPGVERIVHSHKRDYIKGLARLAREAGAAHPRSLGNQLAVLFEGAAALSTSLDDAGP 180 AGEMPGVERIVHSHKRDYIKGLARLAREAGAAHPRSLGNQLAVLFEGAAALSTSLDDAGP Sbjct 121 AGEMPGVERIVHSHKRDYIKGLARLAREAGAAHPRSLGNQLAVLFEGAAALSTSLDDAGP 180 Query 181 WAHARAAAEVLIDQATARPV 200 WAHARAAAE+LIDQATARPV Sbjct 181 WAHARAAAEILIDQATARPV 200 >gi|254233786|ref|ZP_04927111.1| hypothetical transcriptional regulatory protein, tetR/acrR-family [Mycobacterium tuberculosis C] gi|124599315|gb|EAY58419.1| hypothetical transcriptional regulatory protein, tetR/acrR-family [Mycobacterium tuberculosis C] Length=200 Score = 363 bits (931), Expect = 9e-99, Method: Compositional matrix adjust. Identities = 182/191 (96%), Positives = 182/191 (96%), Gaps = 0/191 (0%) Query 10 PPRRGGRGARQRILKAAAELFYCEGINATGVELIANKASVSKRTLYQHFPSKSALVEEYL 69 PP G ILKAAAELFYCEGINATGVELIANKASVSKRTLYQHFPSKSALVEEYL Sbjct 10 PPGAGAAALVSAILKAAAELFYCEGINATGVELIANKASVSKRTLYQHFPSKSALVEEYL 69 Query 70 RGLRQAAGEADKMPKASNATPRERLLALFDRPNRGDGRMRGCPFHNAAVEAAGEMPGVER 129 RGLRQAAGEADKMPKASNATPRERLLALFDRPNRGDGRMRGCPFHNAAVEAAGEMPGVER Sbjct 70 RGLRQAAGEADKMPKASNATPRERLLALFDRPNRGDGRMRGCPFHNAAVEAAGEMPGVER 129 Query 130 IVHSHKRDYIKGLARLAREAGAAHPRSLGNQLAVLFEGAAALSTSLDDAGPWAHARAAAE 189 IVHSHKRDYIKGLARLAREAGAAHPRSLGNQLAVLFEGAAALSTSLDDAGPWAHARAAAE Sbjct 130 IVHSHKRDYIKGLARLAREAGAAHPRSLGNQLAVLFEGAAALSTSLDDAGPWAHARAAAE 189 Query 190 VLIDQATARPV 200 VLIDQATARPV Sbjct 190 VLIDQATARPV 200 >gi|339299615|gb|AEJ51725.1| TetR/ACRR family transcriptional regulator [Mycobacterium tuberculosis CCDC5180] Length=178 Score = 359 bits (922), Expect = 1e-97, Method: Compositional matrix adjust. Identities = 177/178 (99%), Positives = 178/178 (100%), Gaps = 0/178 (0%) Query 23 LKAAAELFYCEGINATGVELIANKASVSKRTLYQHFPSKSALVEEYLRGLRQAAGEADKM 82 +KAAAELFYCEGINATGVELIANKASVSKRTLYQHFPSKSALVEEYLRGLRQAAGEADKM Sbjct 1 MKAAAELFYCEGINATGVELIANKASVSKRTLYQHFPSKSALVEEYLRGLRQAAGEADKM 60 Query 83 PKASNATPRERLLALFDRPNRGDGRMRGCPFHNAAVEAAGEMPGVERIVHSHKRDYIKGL 142 PKASNATPRERLLALFDRPNRGDGRMRGCPFHNAAVEAAGEMPGVERIVHSHKRDYIKGL Sbjct 61 PKASNATPRERLLALFDRPNRGDGRMRGCPFHNAAVEAAGEMPGVERIVHSHKRDYIKGL 120 Query 143 ARLAREAGAAHPRSLGNQLAVLFEGAAALSTSLDDAGPWAHARAAAEVLIDQATARPV 200 ARLAREAGAAHPRSLGNQLAVLFEGAAALSTSLDDAGPWAHARAAAEVLIDQATARPV Sbjct 121 ARLAREAGAAHPRSLGNQLAVLFEGAAALSTSLDDAGPWAHARAAAEVLIDQATARPV 178 >gi|289763356|ref|ZP_06522734.1| conserved hypothetical protein [Mycobacterium tuberculosis GM 1503] gi|289710862|gb|EFD74878.1| conserved hypothetical protein [Mycobacterium tuberculosis GM 1503] Length=137 Score = 283 bits (723), Expect = 1e-74, Method: Compositional matrix adjust. Identities = 137/137 (100%), Positives = 137/137 (100%), Gaps = 0/137 (0%) Query 1 MPPVTRTTEPPRRGGRGARQRILKAAAELFYCEGINATGVELIANKASVSKRTLYQHFPS 60 MPPVTRTTEPPRRGGRGARQRILKAAAELFYCEGINATGVELIANKASVSKRTLYQHFPS Sbjct 1 MPPVTRTTEPPRRGGRGARQRILKAAAELFYCEGINATGVELIANKASVSKRTLYQHFPS 60 Query 61 KSALVEEYLRGLRQAAGEADKMPKASNATPRERLLALFDRPNRGDGRMRGCPFHNAAVEA 120 KSALVEEYLRGLRQAAGEADKMPKASNATPRERLLALFDRPNRGDGRMRGCPFHNAAVEA Sbjct 61 KSALVEEYLRGLRQAAGEADKMPKASNATPRERLLALFDRPNRGDGRMRGCPFHNAAVEA 120 Query 121 AGEMPGVERIVHSHKRD 137 AGEMPGVERIVHSHKRD Sbjct 121 AGEMPGVERIVHSHKRD 137 >gi|254774814|ref|ZP_05216330.1| transcriptional regulator [Mycobacterium avium subsp. avium ATCC 25291] Length=203 Score = 241 bits (615), Expect = 5e-62, Method: Compositional matrix adjust. Identities = 126/182 (70%), Positives = 142/182 (79%), Gaps = 9/182 (4%) Query 22 ILKAAAELFYCEGINATGVELIANKASVSKRTLYQHFPSKSALVEEYLRGLRQAAG---- 77 IL A ELFY +GINATGVE +A +ASVSKRTLYQHFPSK+A+VEEYLRG++QA G Sbjct 22 ILDTATELFYRDGINATGVERLAAEASVSKRTLYQHFPSKNAVVEEYLRGIQQAVGDPIH 81 Query 78 -EADKMPKASNATPRERLLALFDRPNRGDGRMRGCPFHNAAVEAAGEMPGVERIVHSHKR 136 EAD A+N +PR RLLALFD P+ GD MRGCPFHNAAVEA MP V+ IV HKR Sbjct 82 PEAD----ATNRSPRARLLALFDTPSPGDALMRGCPFHNAAVEAGQTMPEVQSIVREHKR 137 Query 137 DYIKGLARLAREAGAAHPRSLGNQLAVLFEGAAALSTSLDDAGPWAHARAAAEVLIDQAT 196 YI GLA LAR AGAA P+ LGNQLAVL+EGAAALSTSL+D PWAHARAAA LID+A Sbjct 138 TYIDGLAELARRAGAADPQVLGNQLAVLYEGAAALSTSLNDPSPWAHARAAAHTLIDRAV 197 Query 197 AR 198 +R Sbjct 198 SR 199 >gi|118463334|ref|YP_881311.1| transcriptional regulator [Mycobacterium avium 104] gi|118164621|gb|ABK65518.1| transcriptional regulator [Mycobacterium avium 104] Length=203 Score = 237 bits (604), Expect = 8e-61, Method: Compositional matrix adjust. Identities = 125/182 (69%), Positives = 140/182 (77%), Gaps = 9/182 (4%) Query 22 ILKAAAELFYCEGINATGVELIANKASVSKRTLYQHFPSKSALVEEYLRGLRQAAG---- 77 IL A ELFY +GINATGVE +A +ASVSKRTLYQHFPSK+A+VEEYLRG++QA G Sbjct 22 ILDTATELFYRDGINATGVERLAAEASVSKRTLYQHFPSKNAVVEEYLRGIQQAVGDPIH 81 Query 78 -EADKMPKASNATPRERLLALFDRPNRGDGRMRGCPFHNAAVEAAGEMPGVERIVHSHKR 136 EAD A+N +PR RLLALFD P GD MRGCPFHNAAVEA MP V IV HKR Sbjct 82 PEAD----ATNRSPRARLLALFDTPAPGDALMRGCPFHNAAVEAGQTMPEVRSIVREHKR 137 Query 137 DYIKGLARLAREAGAAHPRSLGNQLAVLFEGAAALSTSLDDAGPWAHARAAAEVLIDQAT 196 YI GLA LAR AGA+ P+ LGNQLAVL+EGAAALSTSL+D PWAHARAAA LID+A Sbjct 138 TYIDGLAELARRAGASDPQLLGNQLAVLYEGAAALSTSLNDPSPWAHARAAAHTLIDRAV 197 Query 197 AR 198 +R Sbjct 198 SR 199 >gi|240168671|ref|ZP_04747330.1| transcriptional regulator [Mycobacterium kansasii ATCC 12478] Length=195 Score = 229 bits (585), Expect = 1e-58, Method: Compositional matrix adjust. Identities = 119/177 (68%), Positives = 138/177 (78%), Gaps = 1/177 (0%) Query 22 ILKAAAELFYCEGINATGVELIANKASVSKRTLYQHFPSKSALVEEYLRGLRQAAGEADK 81 IL AAAELFY EGINATGVE +A ++SVSKRTLYQHFPSK+A+VEEYLR + A Sbjct 18 ILDAAAELFYREGINATGVERLATESSVSKRTLYQHFPSKTAVVEEYLRSIGDVAANPLH 77 Query 82 MP-KASNATPRERLLALFDRPNRGDGRMRGCPFHNAAVEAAGEMPGVERIVHSHKRDYIK 140 + +A+ TPR RLLALF P G +RGCPFHNAAVEAAG MPGV+ IV + K+ +I Sbjct 78 VSGEAAEQTPRSRLLALFKSPRPGTAPLRGCPFHNAAVEAAGAMPGVQTIVRATKQKFID 137 Query 141 GLARLAREAGAAHPRSLGNQLAVLFEGAAALSTSLDDAGPWAHARAAAEVLIDQATA 197 GL LAR AGA++PRSLGNQLAVL+EGAAAL+TSL+DA WA ARAAAE LIDQA A Sbjct 138 GLIELARAAGASNPRSLGNQLAVLYEGAAALATSLNDASTWAQARAAAETLIDQALA 194 >gi|342859954|ref|ZP_08716606.1| TetR family transcriptional regulator [Mycobacterium colombiense CECT 3035] gi|342132332|gb|EGT85561.1| TetR family transcriptional regulator [Mycobacterium colombiense CECT 3035] Length=195 Score = 187 bits (476), Expect = 5e-46, Method: Compositional matrix adjust. Identities = 103/181 (57%), Positives = 128/181 (71%), Gaps = 5/181 (2%) Query 7 TTEPPRRGGRGARQRILKAAAELFYCEGINATGVELIANKASVSKRTLYQHFPSKSALVE 66 T +P GRGAR+RI +AAA LFY GI+ATGVEL+A++A VSKRTLYQHF SK+ LV+ Sbjct 5 TAQPRPAAGRGARERIERAAARLFYRNGIHATGVELVAHEAGVSKRTLYQHFASKNELVD 64 Query 67 EYLRGLRQAAGEADKMPKASNAT--PRERLLALFDRPNRGDGRMRGCPFHNAAVEAAGEM 124 YLR + ++ G A + +AT RERLLA+FD R +RGCPFHNAAVE+AG + Sbjct 65 NYLRNI-ESRGGAPTEKRLDDATLPARERLLAIFDL--RQSDVVRGCPFHNAAVESAGSL 121 Query 125 PGVERIVHSHKRDYIKGLARLAREAGAAHPRSLGNQLAVLFEGAAALSTSLDDAGPWAHA 184 + IV +HKRD+ L +AREAGAA P LG QLAVLFEGA A++TSL+D P HA Sbjct 122 ATTDEIVRTHKRDFTDRLIAVAREAGAADPHLLGQQLAVLFEGATAMATSLNDTAPVVHA 181 Query 185 R 185 R Sbjct 182 R 182 >gi|126438197|ref|YP_001073888.1| TetR family transcriptional regulator [Mycobacterium sp. JLS] gi|126237997|gb|ABO01398.1| transcriptional regulator, TetR family [Mycobacterium sp. JLS] Length=196 Score = 178 bits (452), Expect = 3e-43, Method: Compositional matrix adjust. Identities = 110/196 (57%), Positives = 133/196 (68%), Gaps = 5/196 (2%) Query 1 MPPVTRTTEPPRRGGRGARQRILKAAAELFYCEGINATGVELIANKASVSKRTLYQHFPS 60 +PPVT T P R GRGAR+RI++AA+ LFY GI+ATGV+L+ +A VSKRT YQHFPS Sbjct 2 LPPVT--TAPAGRRGRGARERIIRAASALFYRRGIHATGVDLLTQEAQVSKRTFYQHFPS 59 Query 61 KSALVEEYLRGLRQAAGE-ADKMPKASNATPRERLLALFDRPNRGDGRMRGCPFHNAAVE 119 K LVE YLR + + G A++ PRERLLA+FD R RGCPFHNAAVE Sbjct 60 KVELVETYLREIAENGGSPAERRLDLPGLGPRERLLAIFD--ASAVKRFRGCPFHNAAVE 117 Query 120 AAGEMPGVERIVHSHKRDYIKGLARLAREAGAAHPRSLGNQLAVLFEGAAALSTSLDDAG 179 +AG + GV+ IV HKR + LA+++ EAGA P LG QL VLFEGA ALSTS+ D Sbjct 118 SAGALEGVDEIVREHKRWFADRLAQVSTEAGARDPYLLGEQLLVLFEGATALSTSMGDTA 177 Query 180 PWAHARAAAEVLIDQA 195 P HAR+AA LID A Sbjct 178 PMVHARSAAAQLIDDA 193 >gi|108802215|ref|YP_642412.1| TetR family transcriptional regulator [Mycobacterium sp. MCS] gi|119871368|ref|YP_941320.1| TetR family transcriptional regulator [Mycobacterium sp. KMS] gi|108772634|gb|ABG11356.1| transcriptional regulator, TetR family [Mycobacterium sp. MCS] gi|119697457|gb|ABL94530.1| transcriptional regulator, TetR family [Mycobacterium sp. KMS] Length=196 Score = 176 bits (445), Expect = 2e-42, Method: Compositional matrix adjust. Identities = 109/196 (56%), Positives = 132/196 (68%), Gaps = 5/196 (2%) Query 1 MPPVTRTTEPPRRGGRGARQRILKAAAELFYCEGINATGVELIANKASVSKRTLYQHFPS 60 +PPVT T P R GRGAR+RI++AA+ LFY GI+ATGV+L+ +A VSKRT YQHFPS Sbjct 2 LPPVT--TAPAGRRGRGARERIIRAASALFYRRGIHATGVDLLTQEAQVSKRTFYQHFPS 59 Query 61 KSALVEEYLRGLRQAAGE-ADKMPKASNATPRERLLALFDRPNRGDGRMRGCPFHNAAVE 119 K LVE YLR + + G A++ PRERLLA+FD R RGCPFHNAAVE Sbjct 60 KVELVETYLREIAENGGSPAERRLDLPGLGPRERLLAIFD--ASAVKRFRGCPFHNAAVE 117 Query 120 AAGEMPGVERIVHSHKRDYIKGLARLAREAGAAHPRSLGNQLAVLFEGAAALSTSLDDAG 179 +AG + V+ IV HKR + LA+++ EAGA P LG QL VLFEGA ALSTS+ D Sbjct 118 SAGALECVDEIVREHKRWFADRLAQVSTEAGARDPYLLGEQLLVLFEGATALSTSMGDTA 177 Query 180 PWAHARAAAEVLIDQA 195 P HAR+AA LID A Sbjct 178 PMVHARSAAAQLIDDA 193 >gi|118471079|ref|YP_886508.1| TetR family transcriptional regulator [Mycobacterium smegmatis str. MC2 155] gi|118172366|gb|ABK73262.1| transcriptional regulator, TetR family protein [Mycobacterium smegmatis str. MC2 155] Length=197 Score = 171 bits (433), Expect = 6e-41, Method: Compositional matrix adjust. Identities = 100/176 (57%), Positives = 122/176 (70%), Gaps = 3/176 (1%) Query 22 ILKAAAELFYCEGINATGVELIANKASVSKRTLYQHFPSKSALVEEYLRGLRQAAGEADK 81 +L +A+ LFY GI+ATGVE + A+VSKRTLYQHF SK+ LVE YLR + A G + Sbjct 18 LLSSASRLFYRNGIHATGVEALIQHANVSKRTLYQHFSSKNELVEHYLRRIDGAGGSPME 77 Query 82 MPKASNATP-RERLLALFDRPNRGDGRMRGCPFHNAAVEAAGEMPGVERIVHSHKRDYIK 140 P + P R+RLLA+FD R RGCPFHNAAVE+AGE+ VE IV HKR + + Sbjct 78 KPLLNQELPPRDRLLAIFDAVPVA--RFRGCPFHNAAVESAGELSAVEDIVRDHKRRFAE 135 Query 141 GLARLAREAGAAHPRSLGNQLAVLFEGAAALSTSLDDAGPWAHARAAAEVLIDQAT 196 L ++A EAGAA P +LG QL VLFEGAAAL+TSL+D G + HARAAA LID A Sbjct 136 LLVQVATEAGAADPYALGPQLLVLFEGAAALATSLNDTGAFVHARAAAAQLIDCAV 191 >gi|331700106|ref|YP_004336345.1| regulatory protein TetR [Pseudonocardia dioxanivorans CB1190] gi|326954795|gb|AEA28492.1| regulatory protein TetR [Pseudonocardia dioxanivorans CB1190] Length=207 Score = 166 bits (419), Expect = 3e-39, Method: Compositional matrix adjust. Identities = 101/194 (53%), Positives = 121/194 (63%), Gaps = 8/194 (4%) Query 10 PPRRGGRGARQRILKAAAELFYCEGINATGVELIANKASVSKRTLYQHFPSKSALVEEYL 69 P +RGGRGAR+RILKA+ ELF +GI+ATG+ + A VS RTLYQHFPSK ALV YL Sbjct 9 PTKRGGRGARERILKASVELFARDGIHATGIAKVTEVAHVSTRTLYQHFPSKEALVSAYL 68 Query 70 RGLR---QAAGEADKMPKASNATPRERLLALFDRPNRGDGR----MRGCPFHNAAVEAAG 122 L E + + + PR+RL+ALF P GD +RGCPFHN AVEAAG Sbjct 69 ERLESDPNGPAEIETVLTRDDLEPRDRLIALFATPA-GDALAGPVLRGCPFHNTAVEAAG 127 Query 123 EMPGVERIVHSHKRDYIKGLARLAREAGAAHPRSLGNQLAVLFEGAAALSTSLDDAGPWA 182 M V HKR+ I L A AGA +P +LG QLAVLFEGA AL+TS++DA P+ Sbjct 128 GMADAAAFVERHKRELIANLIATADAAGAENPEALGRQLAVLFEGARALATSVNDAHPFE 187 Query 183 HARAAAEVLIDQAT 196 AR A LID A Sbjct 188 DARELAVRLIDDAV 201 >gi|208969093|dbj|BAG74315.1| gamma-butyrolactone autoregulator receptor [Amycolatopsis mediterranei] Length=202 Score = 134 bits (338), Expect = 5e-30, Method: Compositional matrix adjust. Identities = 86/182 (48%), Positives = 107/182 (59%), Gaps = 4/182 (2%) Query 15 GRGARQRILKAAAELFYCEGINATGVELIANKASVSKRTLYQHFPSKSALVEEYLRGLRQ 74 GRGAR+RIL+AAA LFY GINATGVE + +A VS RTLY HF K +V YL + Sbjct 12 GRGARERILRAAAHLFYVRGINATGVEELRREADVSVRTLYNHFAGKDDVVVAYLEQMAD 71 Query 75 AAGEADKMPKASNATPRERLLALFDRPNRGDGR-MRGCPFHNAAVEAAGEMPGVERIVHS 133 AAG + ++ PRERLL +F P G +RGCP NA VE A R Sbjct 72 AAGSSLGR---ADLPPRERLLGIFTPPAPKAGDPVRGCPLINAGVELADPDHPAHRYAAE 128 Query 134 HKRDYIKGLARLAREAGAAHPRSLGNQLAVLFEGAAALSTSLDDAGPWAHARAAAEVLID 193 K + + L +AREAGAA P SLG +LA+L++GA+A ST L+ P A A A L+D Sbjct 129 RKARFAERLTEIAREAGAADPESLGQRLALLYDGASARSTVLNSDHPHEVALALATELVD 188 Query 194 QA 195 A Sbjct 189 AA 190 >gi|300787513|ref|YP_003767804.1| TetR family transcriptional regulator [Amycolatopsis mediterranei U32] gi|299797027|gb|ADJ47402.1| TetR family transcriptional regulator [Amycolatopsis mediterranei U32] gi|340529043|gb|AEK44248.1| TetR family transcriptional regulator [Amycolatopsis mediterranei S699] Length=195 Score = 134 bits (338), Expect = 6e-30, Method: Compositional matrix adjust. Identities = 86/182 (48%), Positives = 107/182 (59%), Gaps = 4/182 (2%) Query 15 GRGARQRILKAAAELFYCEGINATGVELIANKASVSKRTLYQHFPSKSALVEEYLRGLRQ 74 GRGAR+RIL+AAA LFY GINATGVE + +A VS RTLY HF K +V YL + Sbjct 5 GRGARERILRAAAHLFYVRGINATGVEELRREADVSVRTLYNHFAGKDDVVVAYLEQMAD 64 Query 75 AAGEADKMPKASNATPRERLLALFDRPNRGDGR-MRGCPFHNAAVEAAGEMPGVERIVHS 133 AAG + ++ PRERLL +F P G +RGCP NA VE A R Sbjct 65 AAGSSLGR---ADLPPRERLLGIFTPPAPKAGDPVRGCPLINAGVELADPDHPAHRYAAE 121 Query 134 HKRDYIKGLARLAREAGAAHPRSLGNQLAVLFEGAAALSTSLDDAGPWAHARAAAEVLID 193 K + + L +AREAGAA P SLG +LA+L++GA+A ST L+ P A A A L+D Sbjct 122 RKARFAERLTEIAREAGAADPESLGQRLALLYDGASARSTVLNSDHPHEVALALATELVD 181 Query 194 QA 195 A Sbjct 182 AA 183 >gi|118471278|ref|YP_890717.1| TetR family transcriptional regulator [Mycobacterium smegmatis str. MC2 155] gi|118172565|gb|ABK73461.1| transcriptional regulator, TetR family protein [Mycobacterium smegmatis str. MC2 155] Length=188 Score = 124 bits (312), Expect = 5e-27, Method: Compositional matrix adjust. Identities = 74/168 (45%), Positives = 100/168 (60%), Gaps = 8/168 (4%) Query 15 GRGARQRILKAAAELFYCEGINATGVELIANKASVSKRTLYQHFPSKSALVEEYLRGLRQ 74 GRG R+RI+ AAA LF +GI AT +E IA KA VSKRTLY HFP+K LV E+L+ + + Sbjct 6 GRGGRERIVAAAAALFEAQGITATTMEQIAAKAPVSKRTLYAHFPTKDDLVVEFLQYVYR 65 Query 75 AAGEADKMPKASNATPRERLLALFDRPNRGDGRMRGCPFHNAAVEAAGEMPGVERIVHSH 134 + + ++ RER+LA+F P RGDG +RGCPF V AA E P + H++ Sbjct 66 SGLTVESALYDADVPARERILAMFTVPTRGDGPVRGCPF----VAAATEFPDPDSPAHAY 121 Query 135 KRD----YIKGLARLAREAGAAHPRSLGNQLAVLFEGAAALSTSLDDA 178 R+ + +A L E GA P L QLA+L +G A+ S +DA Sbjct 122 TRERKQAFTLRIAELLTELGADDPHGLAEQLAILTDGVASRSMVFNDA 169 >gi|300788632|ref|YP_003768923.1| TetR family transcriptional regulator [Amycolatopsis mediterranei U32] gi|299798146|gb|ADJ48521.1| TetR family transcriptional regulator [Amycolatopsis mediterranei U32] gi|340530244|gb|AEK45449.1| TetR family transcriptional regulator [Amycolatopsis mediterranei S699] Length=200 Score = 120 bits (302), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 86/192 (45%), Positives = 109/192 (57%), Gaps = 11/192 (5%) Query 13 RGGRGARQRILKAAAELFYCEGINATGVELIANKASVSKRTLYQHFPSKSALVEEYLRGL 72 R GRGAR+RIL A+ +LF +GIN TG++ + A VSKRT YQHF K LV EYLR Sbjct 12 RRGRGARERILSASQQLFREQGINQTGMDQLCAVAQVSKRTAYQHFAGKDELVAEYLRRF 71 Query 73 RQAAGEADKMPKA---SNATPRERLLALFDRPNRG--DGRMRGCPFHNAAVEAAGEMPGV 127 + D MP+ ++ TPRERLLA+FD P D CPF A+VE V Sbjct 72 -----DPDVMPEVFDRTDLTPRERLLAVFDLPMAAAQDDITPLCPFIAASVEIPDPAHPV 126 Query 128 ERIVHSHKRDYIKGLARLAREAGAAHPRSLGNQLAVLFEGAAALSTSLDDAGPWAHARAA 187 + H +K+ LA AREAGA P LG QLA+L +GA+A + +L + + A A Sbjct 127 RQSAHDYKKAVAARLAEAAREAGATDPEQLGEQLALLLDGASARNRAL-NTETFPTAAAI 185 Query 188 AEVLIDQATARP 199 A VLID A P Sbjct 186 AAVLIDNAIPAP 197 >gi|333990688|ref|YP_004523302.1| TetR family transcriptional regulator [Mycobacterium sp. JDM601] gi|333486656|gb|AEF36048.1| TetR/ACRR family transcriptional regulator [Mycobacterium sp. JDM601] Length=193 Score = 115 bits (289), Expect = 3e-24, Method: Compositional matrix adjust. Identities = 86/193 (45%), Positives = 111/193 (58%), Gaps = 27/193 (13%) Query 13 RGGRGARQRILKAAAELFYCEGINATGVELIANKASVSKRTLYQHFPSKSALVEEYLRGL 72 R GRGAR+RIL+A+ +LF +GIN+TG++ + A VSKRT YQHF K L+ E+LR Sbjct 9 RRGRGARERILRASQQLFRDQGINSTGMDQLCAVAQVSKRTFYQHFSGKDELIAEHLRRF 68 Query 73 RQAAGEADKMPKA---SNATPRERLLALFDRPNRGDGRMRG--CPFHNAAVEAAGEMPGV 127 + D +P+ S+ +PRERLLA FD + G CPF AAV E+ Sbjct 69 -----DPDVLPEVFDRSDLSPRERLLAAFD--------IHGPLCPFIAAAV----EINDP 111 Query 128 ERIVHSHKRDYIKGL-ARL---AREAGAAHPRSLGNQLAVLFEGAAALSTSLDDAGPWAH 183 + H RDY K ARL AREAGA P LG QLA+L +GA+A + L+ +A Sbjct 112 DHPARLHARDYKKAFAARLSATAREAGATDPDQLGEQLALLLDGASARNRVLNSEN-FAT 170 Query 184 ARAAAEVLIDQAT 196 A A A VLID A Sbjct 171 AAAIAAVLIDNAI 183 >gi|302526692|ref|ZP_07279034.1| transcriptional regulator [Streptomyces sp. AA4] gi|302435587|gb|EFL07403.1| transcriptional regulator [Streptomyces sp. AA4] Length=190 Score = 114 bits (286), Expect = 5e-24, Method: Compositional matrix adjust. Identities = 75/178 (43%), Positives = 100/178 (57%), Gaps = 10/178 (5%) Query 22 ILKAAAELFYCEGINATGVELIANKASVSKRTLYQHFPSKSALVEEYLRGLRQAAGEADK 81 +L AAA+LF GI T +E +A A VSKRTLY HFP K LV YLR L ++ Sbjct 17 VLAAAADLFARHGITGTTMEQVAAAAPVSKRTLYLHFPDKDELVVAYLRDLVRSGDTLHD 76 Query 82 MPKASNATPRERLLALFDRPNRGDGRMRGCPFHNAAVEAAGEMPGVERIVHSHKRD---- 137 + ++ PR+RLLA+FD P+ +RGC F V+AA E P + VH + R+ Sbjct 77 VLTRADLPPRQRLLAMFDLPDA--EPVRGCLF----VDAAAEYPDPDSAVHVYAREQKLL 130 Query 138 YIKGLARLAREAGAAHPRSLGNQLAVLFEGAAALSTSLDDAGPWAHARAAAEVLIDQA 195 ++ + L E GAA P L QL L +GAA+ + L D HARAAAEVL++ A Sbjct 131 MLRLVTDLVAELGAADPEGLAEQLVTLADGAASRAMVLGDPKYGRHARAAAEVLLEHA 188 >gi|329934304|ref|ZP_08284383.1| tetR family transcriptional regulator [Streptomyces griseoaurantiacus M045] gi|329305900|gb|EGG49755.1| tetR family transcriptional regulator [Streptomyces griseoaurantiacus M045] Length=213 Score = 111 bits (278), Expect = 5e-23, Method: Compositional matrix adjust. Identities = 77/177 (44%), Positives = 96/177 (55%), Gaps = 13/177 (7%) Query 22 ILKAAAELFYCEGINATGVELIANKASVSKRTLYQHFPSKSALVEEYLRGLRQAAGEADK 81 IL A+ +LF +GIN TG++ + A VSKRT YQHF K LV EYLR + D Sbjct 21 ILGASQQLFREQGINRTGMDQLCAAAQVSKRTAYQHFTGKDELVAEYLRRF-----DPDV 75 Query 82 MPKA---SNATPRERLLALFDRPNRGDGRMRGCPFHNAAVEAAGEMPGVERIVHSHKRDY 138 MP ++ TPRERLLA FD P M CP+ AAVE R +K Sbjct 76 MPGVFDRTDLTPRERLLAAFDMP----ASMPLCPYIAAAVELHDPQHPASRYAREYKIAI 131 Query 139 IKGLARLAREAGAAHPRSLGNQLAVLFEGAAALSTSLDDAGPWAHARAAAEVLIDQA 195 LA AREAGA P LG QLA+L +GA+A T + ++ ++ A A A VLID A Sbjct 132 AARLAETAREAGATDPEQLGEQLALLIDGASA-RTRVTNSESFSTAAAIAAVLIDNA 187 >gi|302556341|ref|ZP_07308683.1| transcriptional regulator [Streptomyces viridochromogenes DSM 40736] gi|302473959|gb|EFL37052.1| transcriptional regulator [Streptomyces viridochromogenes DSM 40736] Length=202 Score = 105 bits (262), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 74/184 (41%), Positives = 97/184 (53%), Gaps = 5/184 (2%) Query 14 GGRGARQRILKAAAELFYCEGINATGVELIANKASVSKRTLYQHFPSKSALVEEYLRGLR 73 G R AR+R+L++AA LFY GI ATGV++I+ ASV K +LY+HFPSK LV LR Sbjct 17 GTRDARERVLRSAAALFYEHGIGATGVDVISEHASVGKMSLYRHFPSKDDLVVAVLRFRD 76 Query 74 QAAGEADKMPKASNATPRERLLALFDRPNRGDGR--MRGCPFHNAAVEAAGEMPGVERIV 131 Q D + S+ PR ++ +FDR R R GCPF A +E PG ++V Sbjct 77 QT--HLDWLLPQSDLDPRRQVAGMFDRIGRAATRPGFHGCPFVRAGLELPVGHPG-RQVV 133 Query 132 HSHKRDYIKGLARLAREAGAAHPRSLGNQLAVLFEGAAALSTSLDDAGPWAHARAAAEVL 191 HK L LA+ AA P +L Q+ L +GAAA P ARA A + Sbjct 134 RDHKARLRARLRTLAQALHAADPVALAWQVVTLADGAAAECVLQGSGTPARAARAVAMLA 193 Query 192 IDQA 195 +D A Sbjct 194 LDAA 197 >gi|111019703|ref|YP_702675.1| TetR family transcriptional regulator [Rhodococcus jostii RHA1] gi|110819233|gb|ABG94517.1| probable transcriptional regulator, TetR family protein [Rhodococcus jostii RHA1] Length=208 Score = 104 bits (260), Expect = 7e-21, Method: Compositional matrix adjust. Identities = 72/172 (42%), Positives = 93/172 (55%), Gaps = 5/172 (2%) Query 19 RQRILKAAAELFYCEGINATGVELIANKASVSKRTLYQHFPSKSALVEEYL--RGLRQAA 76 R R+LKAA +LF+ EGI A G+ I ++A TLY+HF SK L YL RG R A Sbjct 9 RDRLLKAADDLFFKEGIRAVGINRILDEAQTPIMTLYRHFGSKDGLAAAYLERRGERNAE 68 Query 77 GEADKMPKASNATPRERLLALFDRPNRG--DGRMRGCPFHNAAVEAAGEMPGVERIVHSH 134 A ++ K ++ TPRE++LA FD G G RGCPF NA VE A V +I + Sbjct 69 EVASELAKRAS-TPREKILATFDIIVEGLEQGEFRGCPFINATVEMASPDHEVAKIARRY 127 Query 135 KRDYIKGLARLAREAGAAHPRSLGNQLAVLFEGAAALSTSLDDAGPWAHARA 186 K + A A EAG P L QL VL +GAAA + D+ +AR+ Sbjct 128 KEAGRQWFAEFAAEAGVPDPAGLAIQLTVLLDGAAAAAALYQDSSGATYARS 179 >gi|332285539|ref|YP_004417450.1| transcriptional regulator [Pusillimonas sp. T7-7] gi|330429492|gb|AEC20826.1| transcriptional regulator [Pusillimonas sp. T7-7] Length=202 Score = 103 bits (258), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 70/187 (38%), Positives = 92/187 (50%), Gaps = 2/187 (1%) Query 11 PRRGGRGARQRILKAAAELFYCEGINATGVELIANKASVSKRTLYQHFPSKSALVEEYLR 70 P AR RIL A+ LFY +GIN GV I + + V+K TLY HF SK+ ++ L Sbjct 4 PTGSTSSARLRILSCASNLFYRKGINHVGVNEIIDASGVAKMTLYHHFKSKNDIIAATLD 63 Query 71 GLRQAAGEADKMPKASNATPRERLLALFDRPNR--GDGRMRGCPFHNAAVEAAGEMPGVE 128 R E + A TPR ++LA FD D RGC F NA VE A Sbjct 64 TRRAQRLEGIQAAMAQARTPRHQILAAFDYLAEIIEDSTFRGCAFINATVELAEPAHPAS 123 Query 129 RIVHSHKRDYIKGLARLAREAGAAHPRSLGNQLAVLFEGAAALSTSLDDAGPWAHARAAA 188 I HK+ I R+A +AG +PR Q +L++GA A + D P AR+A Sbjct 124 LISTQHKQRMIGEFERVAEQAGWHNPRRFALQCQLLWDGAIAAAQINYDNAPVQAARSAV 183 Query 189 EVLIDQA 195 E+LI+ A Sbjct 184 EILIEAA 190 >gi|119964095|ref|YP_946391.1| TetR family transcriptional regulator [Arthrobacter aurescens TC1] gi|119950954|gb|ABM09865.1| putative transcriptional regulator, TetR family [Arthrobacter aurescens TC1] Length=187 Score = 103 bits (258), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 75/182 (42%), Positives = 97/182 (54%), Gaps = 10/182 (5%) Query 19 RQRILKAAAELFYCEGINATGVELIANKASVSKRTLYQHFPSKSALVEEYLRGLRQAAGE 78 R RI+ A EL+ +GI A G++ + + A VS + LY FPSKS++V L Q+ + Sbjct 7 RNRIVATADELYNAKGIQAVGMDELRSAAGVSLKKLYGEFPSKSSIVMAVLEHRHQSWTQ 66 Query 79 ADKMPKASNATPRERLLALFDRPN--RGDGRMRGCPFHNAAVEAAGEMPGVERIVHSHKR 136 TPRERLLA+FD RGC F N+ E P V HK Sbjct 67 GLDATVQQAGTPRERLLAIFDYLAGWFCQDSFRGCGFINSFAELGAISPDVAEYARKHKE 126 Query 137 DYIKGLARLAREAGAAHPRSLGNQLAVLFEGA---AALSTSLDDAGPWAHARAAAEVLID 193 + + +ARLA EAGA P+ L QLA+L EGA AA++ + D AG AR AAEVLID Sbjct 127 SFQEYVARLAGEAGA--PKYLAPQLAILAEGAQTTAAIAGTSDAAG---QARQAAEVLID 181 Query 194 QA 195 A Sbjct 182 AA 183 >gi|345010076|ref|YP_004812430.1| regulatory protein TetR [Streptomyces violaceusniger Tu 4113] gi|344036425|gb|AEM82150.1| regulatory protein TetR [Streptomyces violaceusniger Tu 4113] Length=203 Score = 102 bits (255), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 75/176 (43%), Positives = 97/176 (56%), Gaps = 11/176 (6%) Query 22 ILKAAAELFYCEGINATGVELIANKASVSKRTLYQHFPSKSALVEEYLRGLRQA--AGEA 79 I+ A+ +LF +GIN TG++ + A VSKRT YQHF K LV +YLR + +G Sbjct 21 IVSASQQLFREQGINRTGMDQLCAAAQVSKRTAYQHFTGKDELVADYLRRFDPSVLSGVF 80 Query 80 DKMPKASNATPRERLLALFDRPNRGDGRMRGCPFHNAAVEAAGEMPGVERIVHSHKRDYI 139 D+ ++ TPRERLLA FD P CP+ AAVE + +K+ Sbjct 81 DR----TDLTPRERLLAAFDVP----PTTPLCPYIAAAVELHDPQHPASQYARDYKKAVA 132 Query 140 KGLARLAREAGAAHPRSLGNQLAVLFEGAAALSTSLDDAGPWAHARAAAEVLIDQA 195 LA AREAGAA P LG QLA+L +GAAA + L +A + A A A VLID A Sbjct 133 ARLADTAREAGAADPEQLGEQLALLIDGAAARTRVL-NADAFPTAAAIAAVLIDNA 187 >gi|343926505|ref|ZP_08766010.1| putative TetR family transcriptional regulator [Gordonia alkanivorans NBRC 16433] gi|343763743|dbj|GAA12936.1| putative TetR family transcriptional regulator [Gordonia alkanivorans NBRC 16433] Length=190 Score = 101 bits (251), Expect = 7e-20, Method: Compositional matrix adjust. Identities = 75/184 (41%), Positives = 98/184 (54%), Gaps = 14/184 (7%) Query 19 RQRILKAAAELFYCEGINATGVELIANKASVSKRTLYQHFPSKSALVEEYL--RGLRQAA 76 R+R+++AA ELF G++A G++ + + A VS + +Y FPSK AL+ L R + A Sbjct 12 RERVIRAADELFNAYGVHAVGMDKVRDAAGVSLKKIYSLFPSKEALILAVLDDRTRQWNA 71 Query 77 GEADKMPKASNATPRERLLALFD--RPNRGDGRMRGCPFHNAAVEAAGEMPGVERIVHSH 134 G A + S TPRE+LLA+FD G RGC F NA E GE+P V V Sbjct 72 GVAARTEDLS--TPREKLLAIFDFLLEWFGTDEFRGCAFINAYGELGGELPSVVEAVRKQ 129 Query 135 K---RDYIKGLARLAREAGAAHPRSLGNQLAVLFEGAAALSTSLDDAGPWAHARAAAEVL 191 K +DY+ G L E G P L QLA+L EGA + A AR+AAE L Sbjct 130 KCAFQDYVAG---LVEELGG--PSQLAAQLAILAEGAQTTAAIAGTAQAAGDARSAAETL 184 Query 192 IDQA 195 IDQA Sbjct 185 IDQA 188 >gi|23015276|ref|ZP_00055057.1| COG1309: Transcriptional regulator [Magnetospirillum magnetotacticum MS-1] Length=199 Score = 100 bits (249), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 70/179 (40%), Positives = 95/179 (54%), Gaps = 5/179 (2%) Query 18 ARQRILKAAAELFYCEGINATGVELIANKASVSKRTLYQHFPSKSALVEEYLRGLRQAA- 76 AR RIL AA +LFY EGI A G++ + +A V+K +LY+ FPSK L+ +L +R + Sbjct 10 ARDRILAAANDLFYREGIRAIGIDTVIERAGVAKMSLYRAFPSKDDLIAAFLE-MRDSMY 68 Query 77 -GEADKMPKASNATPRERLLALFDRPNR--GDGRMRGCPFHNAAVEAAGEMPGVERIVHS 133 D + PR +LLALF+ R D RGCPF N +VE +V Sbjct 69 WDWWDAVLARHPNDPRRQLLALFETVARRTSDPLYRGCPFVNTSVEFPHPDHPARAVVAR 128 Query 134 HKRDYIKGLARLAREAGAAHPRSLGNQLAVLFEGAAALSTSLDDAGPWAHARAAAEVLI 192 H + + L LA G +L +QL VL EGA + ++L AGP A AAAE+LI Sbjct 129 HFAELRRRLGALAEGIGLPQSSALTDQLMVLLEGAYSACSTLGGAGPSASVAAAAEILI 187 >gi|334111847|ref|ZP_08486115.1| regulatory protein TetR [Methylomicrobium album BG8] gi|333598215|gb|EGL03043.1| regulatory protein TetR [Methylomicrobium album BG8] Length=189 Score = 99.0 bits (245), Expect = 3e-19, Method: Compositional matrix adjust. Identities = 74/186 (40%), Positives = 104/186 (56%), Gaps = 15/186 (8%) Query 19 RQRILKAAAELFYCEGINATGVELIANKASVSKRTLYQHFPSKSALVEEYLRGLRQAAGE 78 ++RIL+ A+ELFY +GI ATGV+ I A +K +LY +FPSK+ LV +L+ + E Sbjct 6 KERILQTASELFYRQGIRATGVDAIVKAAGTTKMSLYHYFPSKNDLVLAHLQKTAETMRE 65 Query 79 ADKMPKASNAT-PRERLLALFDRPNR---GDGRMRGCPFHNAAVEAAGE-----MPGVER 129 A+ A+ P+ RLLA+FD DG RGCPF NAA E+A E + V+ Sbjct 66 KILGGIAARASEPKARLLAVFDVFGELLASDG-FRGCPFINAATESAAEGEPFRLASVDF 124 Query 130 IVHSHKRDYIKGLARLAREAGAAHPRSLGNQLAVLFEGAAALSTSLDDAGPWAHARAAAE 189 + +R L +LA EA A P L QL++L GA D+G ARAAAE Sbjct 125 YLQFRRR-----LTQLAEEAEARQPELLARQLSLLISGAIVAEQMQRDSGAMQAARAAAE 179 Query 190 VLIDQA 195 +LI+++ Sbjct 180 ILINRS 185 >gi|229818636|ref|YP_002880162.1| TetR family transcriptional regulator [Beutenbergia cavernae DSM 12333] gi|229564549|gb|ACQ78400.1| transcriptional regulator, TetR family [Beutenbergia cavernae DSM 12333] Length=181 Score = 98.2 bits (243), Expect = 6e-19, Method: Compositional matrix adjust. Identities = 71/178 (40%), Positives = 89/178 (50%), Gaps = 6/178 (3%) Query 18 ARQRILKAAAELFYCEGINATGVELIANKASVSKRTLYQHFPSKSALVEEYLRGLRQAAG 77 A Q++L AA LFY GINA ++ I + VS + YQ FPSK LVE LR +R A Sbjct 6 AEQKLLDAADALFYDRGINAVSMDAIREVSGVSLKRTYQLFPSKEHLVEAVLR-VRDTAI 64 Query 78 EADKMPKAS-NATPRERLLALFDRPNR--GDGRMRGCPFHNAAVEAAGEMPGVERIVHSH 134 D S TP E++LA+FD RGC F N+ E G PGV +V +H Sbjct 65 RQDLAAYTSARTTPTEQILAVFDYLYDWFSTPEFRGCAFINSFAELRGSSPGVVDVVRTH 124 Query 135 KRDYIKGLARLAREAGAAHPRSLGNQLAVLFEGAAALSTSLDDAGPWAHARAAAEVLI 192 KR +A L EAG P +L QL +L GA + D P AR AAE L+ Sbjct 125 KRAVADLIAVLVAEAG--RPTTLAGQLLILANGAMVTAAIADSPQPAREARDAAERLL 180 >gi|145596506|ref|YP_001160803.1| regulatory protein TetR [Salinispora tropica CNB-440] gi|145305843|gb|ABP56425.1| regulatory protein, TetR [Salinispora tropica CNB-440] Length=225 Score = 97.4 bits (241), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 71/181 (40%), Positives = 94/181 (52%), Gaps = 7/181 (3%) Query 19 RQRILKAAAELFYCEGINATGVELIANKASVSKRTLYQHFPSKSALVEEYLRGLRQAAGE 78 R+ +L A L+Y GI+A G++++ +++ VS R LYQ FPSK LVE L RQ Sbjct 16 REHVLGTADRLYYHRGIHAVGMDVLRDESGVSLRRLYQLFPSKETLVEAVLHRRRQIWNT 75 Query 79 -ADKMPKASNATPRERLLALFD---RPNRGDGRMRGCPFHNAAVEAAGEMPGVERIVHSH 134 D A TPR +LLA++D R + DG RGC F NA E G P + +V Sbjct 76 WVDDAVAAGGGTPRGQLLAIYDMLARWSTEDG-FRGCIFVNAFSELGGTTPHIAALVRDQ 134 Query 135 KRDYIKGLARLAREAGAAHPRSLGNQLAVLFEGAAALSTSLDDAGPWAHARAAAEVLIDQ 194 K + + LA + GA +L +QLAVL EGA + P HAR AA LID Sbjct 135 KVQFQQRLAGIVAATGAP--AALADQLAVLAEGAQTTAAITGTDSPVHHARTAATTLIDT 192 Query 195 A 195 A Sbjct 193 A 193 >gi|344942738|ref|ZP_08782025.1| regulatory protein TetR [Methylobacter tundripaludum SV96] gi|344260025|gb|EGW20297.1| regulatory protein TetR [Methylobacter tundripaludum SV96] Length=203 Score = 97.4 bits (241), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 70/189 (38%), Positives = 98/189 (52%), Gaps = 25/189 (13%) Query 19 RQRILKAAAELFYCEGINATGVELIANKASVSKRTLYQHFPSKSALVEEYLRG------- 71 +++IL+AA+ELFY +GI ATGV+ I A+ +K +LY++F SK LV +LR Sbjct 6 QEKILQAASELFYSQGIRATGVDAIVKAANTTKMSLYKYFLSKDDLVLAFLRKRDEDFRV 65 Query 72 --LRQAAGEADKMPKASNATPRERLLALFDRPNRGDG--RMRGCPFHNAAVEAAGEMPGV 127 + Q +AD TP+ +LLA+FD RGC F NAA E E V Sbjct 66 WFVEQVDAKAD--------TPKAKLLAVFDVIGEWMAVPEFRGCAFINAAAEFPLEGNPV 117 Query 128 ERI---VHSHKRDYIKGLARLAREAGAAHPRSLGNQLAVLFEGAAALSTSLDDAGPWAHA 184 ++ + H R YI A LA + G+ P SL QL++L EGA +G A Sbjct 118 HQVSAEFYDHFRSYI---ADLAGQCGSKSPESLALQLSLLVEGAIVSEQMKRHSGSAEQA 174 Query 185 RAAAEVLID 193 + AA VLI+ Sbjct 175 KQAAIVLIE 183 >gi|27380233|ref|NP_771762.1| transcriptional regulator [Bradyrhizobium japonicum USDA 110] gi|27353387|dbj|BAC50387.1| transcriptional regulatory protein [Bradyrhizobium japonicum USDA 110] Length=208 Score = 97.1 bits (240), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 67/179 (38%), Positives = 91/179 (51%), Gaps = 9/179 (5%) Query 19 RQRILKAAAELFYCEGINATGVELIANKASVSKRTLYQHFPSKSALVEEYLRGLRQAAGE 78 ++RIL+ A +LFY +GI A GV+ IA + +SKRTLY HFPSK AL+ YL A Sbjct 26 KERILETADKLFYLQGIRAIGVDTIAAEIGISKRTLYNHFPSKDALIAAYLERRFVA--- 82 Query 79 ADKMPKASNATPRERLLALFDRPNR--GDGRMRGCPFHNAAVEAAGEMPGVERIVHSHKR 136 P+ S+ P E++LA FD R RGCPF NA E + V +I + K Sbjct 83 ----PRPSDKPPAEQILATFDSLERRFAAKDFRGCPFVNAVAELGPKDRAVRKIAVAFKE 138 Query 137 DYIKGLARLAREAGAAHPRSLGNQLAVLFEGAAALSTSLDDAGPWAHARAAAEVLIDQA 195 E G A+ +L QL +L +G+ A DD A+ AA+VL+ A Sbjct 139 SRRVWFRERLNELGVANADALATQLVLLVDGSIAQDLVRDDPAMARAAKEAAKVLLRNA 197 >gi|83311987|ref|YP_422251.1| transcriptional regulator [Magnetospirillum magneticum AMB-1] gi|82946828|dbj|BAE51692.1| Transcriptional regulator [Magnetospirillum magneticum AMB-1] Length=216 Score = 97.1 bits (240), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 65/178 (37%), Positives = 93/178 (53%), Gaps = 3/178 (1%) Query 18 ARQRILKAAAELFYCEGINATGVELIANKASVSKRTLYQHFPSKSALVEEYLRGLRQAAG 77 AR RIL AA +LFY EGI A G++ + +A V+K +LY+ FPSK L+ +L + Sbjct 27 ARDRILAAANDLFYREGIRAIGIDTVIERAGVAKMSLYRAFPSKDDLIAAFLEMRDKMYW 86 Query 78 EA-DKMPKASNATPRERLLALFDRPNR--GDGRMRGCPFHNAAVEAAGEMPGVERIVHSH 134 E D + R +L ALF+ R + RGCPF N +VE +V H Sbjct 87 EWWDGVMARHPDDSRRQLRALFEAVARRTSGSQYRGCPFVNMSVEFPDHAHPGRLVVARH 146 Query 135 KRDYIKGLARLAREAGAAHPRSLGNQLAVLFEGAAALSTSLDDAGPWAHARAAAEVLI 192 + + L+ L G A P+SL +QL +L EGA + ++ GP A A A AE++I Sbjct 147 MEELRRRLSTLVEGLGLAQPKSLTDQLMLLLEGAYSAGNTMGADGPSASAAACAEIII 204 >gi|134099989|ref|YP_001105650.1| TetR family transcriptional regulator [Saccharopolyspora erythraea NRRL 2338] gi|291003019|ref|ZP_06560992.1| TetR family transcriptional regulator [Saccharopolyspora erythraea NRRL 2338] gi|133912612|emb|CAM02725.1| transcriptional regulator, TetR family [Saccharopolyspora erythraea NRRL 2338] Length=197 Score = 96.3 bits (238), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 79/197 (41%), Positives = 106/197 (54%), Gaps = 15/197 (7%) Query 7 TTEPPRRGGRG-----ARQRILKAAAELFYCEGINATGVELIANKASVSKRTLYQHFPSK 61 TT P G RG AR+R+L AA ELFY +GI A G++ + +A V+K +LY+HF SK Sbjct 3 TTSTPA-GARGGARPPARERLLDAAGELFYRDGIRAVGIDAVIERAGVAKMSLYKHFRSK 61 Query 62 SALVEEYLRGLRQAAGE--ADKMPKASNATPRERLLALFD-RPNRGDGRM-RGCPFHNAA 117 LV YL+ Q E +M +A+ TPRER+LA+FD N + RGC F NA Sbjct 62 DDLVVAYLQRREQRWREHFQSRM-RAAGTTPRERVLAVFDVLANWTESENPRGCAFINAY 120 Query 118 VEAAGE-MPGVERIVHSHKRDYIKG-LARLAREAGAAHPRSLGNQLAVLFEGAAALSTSL 175 VE A PG V +++++ L L E A P +L QL +L EGA + Sbjct 121 VELADAGHPG--NAVARADKEWLRAYLTELVAETRAPDPETLSAQLFLLLEGALVTTAMG 178 Query 176 DDAGPWAHARAAAEVLI 192 G + ARAAAE L+ Sbjct 179 TVDGAMSSARAAAERLL 195 >gi|256824670|ref|YP_003148630.1| transcriptional regulator [Kytococcus sedentarius DSM 20547] gi|256688063|gb|ACV05865.1| transcriptional regulator [Kytococcus sedentarius DSM 20547] Length=198 Score = 95.1 bits (235), Expect = 6e-18, Method: Compositional matrix adjust. Identities = 70/181 (39%), Positives = 95/181 (53%), Gaps = 6/181 (3%) Query 20 QRILKAAAELFYCEGINATGVELIANKASVSKRTLYQHFPSKSALVEEYLRGLRQAAGEA 79 QRI++ A+ELFY GI+A GV+ IA ++ ++KRTLY F SK ALV YL+ Q E Sbjct 13 QRIVEVASELFYRRGIHAVGVDTIARESGITKRTLYDRFGSKDALVAVYLQSRHQRWWEL 72 Query 80 DKMPKASNATPRERLLALFD-RPNRGDGRMRGCPFHNAAVEAAGEMPGVERIVHSHKRDY 138 + + TP R+LA+FD + RGC F NAA E A E P + +V +HK+ Sbjct 73 --LERRITDTPSPRVLAVFDAYADDEWASDRGCGFLNAAGELAAEHPAYQ-VVRAHKQAV 129 Query 139 IKGLARLARE--AGAAHPRSLGNQLAVLFEGAAALSTSLDDAGPWAHARAAAEVLIDQAT 196 LA L R P ++ L +L EGA A D+ AR AE L+ + T Sbjct 130 RDRLAELVRADCLNVDDPETMAAHLFLLLEGAIAHRGIDDETALLTSARELAEHLVLRPT 189 Query 197 A 197 A Sbjct 190 A 190 >gi|344999087|ref|YP_004801941.1| TetR family transcriptional regulator [Streptomyces sp. SirexAA-E] gi|344314713|gb|AEN09401.1| transcriptional regulator, TetR family [Streptomyces sp. SirexAA-E] Length=198 Score = 94.7 bits (234), Expect = 7e-18, Method: Compositional matrix adjust. Identities = 71/181 (40%), Positives = 93/181 (52%), Gaps = 14/181 (7%) Query 18 ARQRILKAAAELFYCEGINATGVELIANKASVSKRTLYQHFPSKSALVEEYL-----RGL 72 AR+R+L AA +LFY G+ A G++ + N + VS + LYQ FPSK ALV E+L R L Sbjct 8 ARERVLDAAEKLFYSRGVQAVGMDAVRNTSGVSLKRLYQLFPSKEALVLEFLRQRDARWL 67 Query 73 RQAAGEADKMPKASNATPRERLLALFDRPNR--GDGRMRGCPFHNAAVEAAGEMPGVERI 130 R A + + + P ER+ A+FD + RGC F NA E + P V Sbjct 68 RVLAEHVE-----ARSAPEERIAAVFDWLYEWFSEPDYRGCAFVNAFGEMSAVSPDVAAR 122 Query 131 VHSHKRDYIKGLARLAREAGAAHPRSLGNQLAVLFEGAAALSTSLDDAGPWAHARAAAEV 190 HKR + LA+L AG P L +QLA+L EGA + L P AR AA V Sbjct 123 ARHHKRAFHGYLAQLVTAAG--RPVELADQLALLAEGAIVTAAVLGTPEPALRARDAACV 180 Query 191 L 191 L Sbjct 181 L 181 >gi|323527493|ref|YP_004229646.1| regulatory protein TetR [Burkholderia sp. CCGE1001] gi|323384495|gb|ADX56586.1| regulatory protein TetR [Burkholderia sp. CCGE1001] Length=223 Score = 94.4 bits (233), Expect = 9e-18, Method: Compositional matrix adjust. Identities = 70/184 (39%), Positives = 90/184 (49%), Gaps = 13/184 (7%) Query 2 PPVTRTTEPPRRG------GRGARQRILKAAAELFYCEGINATGVELIANKASVSKRTLY 55 PP + PRR G A+Q +L+AA ELFY EG+ A GV+ + +A V+K +LY Sbjct 13 PPASGPVGAPRRARGTHTTGPEAQQHLLRAADELFYREGVRAVGVDAVVERAGVNKMSLY 72 Query 56 QHFPSKSALVEEYL-RGLRQAAGEADKMPKASNATPRERLLALFD----RPNRGDGRMRG 110 + F SK LV YL R Q G +K P +L FD R + D RG Sbjct 73 RQFSSKDELVMAYLERKDAQFFGYVEKSFAKHPGEPARQLQQYFDDLAARASLED--YRG 130 Query 111 CPFHNAAVEAAGEMPGVERIVHSHKRDYIKGLARLAREAGAAHPRSLGNQLAVLFEGAAA 170 CPF N AVE + + V +K + L LA AGA P LGN LA+L EG A Sbjct 131 CPFVNVAVEFSDTGHAARQFVFRNKERLLARLTELATAAGADDPELLGNALALLIEGVYA 190 Query 171 LSTS 174 S + Sbjct 191 ASQT 194 >gi|333986091|ref|YP_004515301.1| regulatory protein TetR [Methylomonas methanica MC09] gi|333810132|gb|AEG02802.1| regulatory protein TetR [Methylomonas methanica MC09] Length=189 Score = 94.4 bits (233), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 60/157 (39%), Positives = 85/157 (55%), Gaps = 3/157 (1%) Query 15 GRGARQRILKAAAELFYCEGINATGVELIANKASVSKRTLYQHFPSKSALVEEYLRGLR- 73 R ++ IL+AA+ LFY +GI +TGV+ I A +K +LY++FPSK LV +L R Sbjct 2 SRNLQKHILQAASALFYRQGIKSTGVDAIVKAAGTTKMSLYKYFPSKDDLVLAHLCQSRT 61 Query 74 QAAGEADKMPKASNATPRERLLALFDRPN--RGDGRMRGCPFHNAAVEAAGEMPGVERIV 131 ++ TPR++LLA+FD + RGCPF NAA E A E V++ Sbjct 62 NTLTHIQSAIDSAGQTPRQKLLAIFDVFDAMLDTPEFRGCPFINAAAEFAEENNPVQKAA 121 Query 132 HSHKRDYIKGLARLAREAGAAHPRSLGNQLAVLFEGA 168 + D+ K LA LA +AG+ L QL +L GA Sbjct 122 AAFYADFGKLLADLAAQAGSRDAEQLAAQLTLLIAGA 158 >gi|159038454|ref|YP_001537707.1| TetR family transcriptional regulator [Salinispora arenicola CNS-205] gi|157917289|gb|ABV98716.1| transcriptional regulator, TetR family [Salinispora arenicola CNS-205] Length=202 Score = 94.0 bits (232), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 64/174 (37%), Positives = 93/174 (54%), Gaps = 10/174 (5%) Query 1 MPPVTR---TTEPPRRGGRGARQRILKAAAELFYCEGINATGVELIANKASVSKRTLYQH 57 MP TR T++P + + R+ +L +A L+Y GI+ G++ + +A VS + LYQ Sbjct 1 MPAKTRSRSTSQP--QTDQAIREHVLISADRLYYSRGIHNVGMDALRAEAGVSLKRLYQL 58 Query 58 FPSKSALVEEYLRGLRQAAGEADKMPKASNA-TPRERLLALFDR-PNRGD-GRMRGCPFH 114 FPSK LVE L R + A+ TPR++LLA++D N D RGC F Sbjct 59 FPSKENLVEAVLHRRRHIWNNLVETAIATGGDTPRDQLLAVYDMLANWFDEDDFRGCVFI 118 Query 115 NAAVEAAGEMPGVERIVHSHKRDYIKGLARLAREAGAAHPRSLGNQLAVLFEGA 168 N E P + ++ HK D+ + LA+L E GA P +L +QLA+L EGA Sbjct 119 NTFGELGATTPHIATLIRDHKADFQRRLAKLVTETGA--PATLAHQLAILAEGA 170 >gi|256378504|ref|YP_003102164.1| TetR family transcriptional regulator [Actinosynnema mirum DSM 43827] gi|255922807|gb|ACU38318.1| transcriptional regulator, TetR family [Actinosynnema mirum DSM 43827] Length=205 Score = 93.6 bits (231), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 71/177 (41%), Positives = 89/177 (51%), Gaps = 8/177 (4%) Query 23 LKAAAELFYCEGINATGVELIANKASVSKRTLYQHFPSKSALVEEYLRGLRQAAGEADKM 82 L AA LF GI AT +E +A A VSKRTLY HFP+K LV L L + Sbjct 19 LAAAVRLFDERGITATTMEEVAAAAPVSKRTLYAHFPTKEDLVLAQLDHLLGSGATMLDA 78 Query 83 PKASNATPRERLLALFDRPNRGDGRMRGCPFHNAAVEAAGEMPGVERIVHSHKRD---YI 139 + PRERLL +F G +R CPF + AA E P + H+ R+ + Sbjct 79 LRDEAVPPRERLLGMFGLGLWPRGNVRSCPF----LRAATEDPDPDGRAHAFAREQKLVM 134 Query 140 KGLAR-LAREAGAAHPRSLGNQLAVLFEGAAALSTSLDDAGPWAHARAAAEVLIDQA 195 LA L E G A P +L QL L +G A+ + L+D HARAAAEVL+D A Sbjct 135 LALATGLVAELGIAEPEALAEQLVTLSDGVASRAMVLNDPDYGRHARAAAEVLLDHA 191 >gi|333919870|ref|YP_004493451.1| putative TetR family transcriptional regulator [Amycolicicoccus subflavus DQS3-9A1] gi|333482091|gb|AEF40651.1| putative transcriptional regulator, TetR family protein [Amycolicicoccus subflavus DQS3-9A1] Length=182 Score = 93.6 bits (231), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 70/179 (40%), Positives = 94/179 (53%), Gaps = 10/179 (5%) Query 26 AAELFYCEGINATGVELIANKASVSKRTLYQHFPSKSALVEEYLRGL-RQAAGEADKMPK 84 AA+LFY EGI A GV + +A +LY+ F SK LVEE+LR +Q ++ + Sbjct 3 AAQLFYSEGIRAVGVNRLLEEAQTPIMSLYRIFGSKEGLVEEFLREKDKQIRERFEREIE 62 Query 85 ASNATPRERLLALFDRPNR--GDGRMRGCPFHNAAVEAAG-EMPGVERIVHSHKRDYIKG 141 P+ER+LA+FD D RGC F N AVE A E P VE I SHK + Sbjct 63 RIANAPKERILAVFDVLGEVIADSDYRGCTFINVAVEMANTEHPFVE-IAVSHKNSVRET 121 Query 142 LARLAREAGAAHPRSLGNQLAVLFEGA---AALSTSLDDAGPWAHARAAAEVLIDQATA 197 +R +AG L QL +L +GA A + ++ ++ HAR AAEVL+D A A Sbjct 122 FSRYLADAGLRETEPLATQLLMLMDGAFVRAQMHSNREEVA--LHARMAAEVLVDAALA 178 >gi|345462058|ref|YP_003325974.2| TetR family transcriptional regulator [Xylanimonas cellulosilytica DSM 15894] Length=184 Score = 93.6 bits (231), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 74/193 (39%), Positives = 97/193 (51%), Gaps = 20/193 (10%) Query 18 ARQRILKAAAELFYCEGINATGVELIANKASVSKRTLYQHFPSKSALV--------EEYL 69 AR R++ AA LFY G++A G++ + A VS + +YQ FPSK LV E++ Sbjct 2 ARGRVVTAADRLFYAHGVHAVGMDAVRAAAEVSLKRIYQLFPSKDDLVIGVLHHRTEQWT 61 Query 70 RGLRQAAGEADKMPKASNATPRERLLALFDRPNRG--DGRMRGCPFHNAAVEAAGEMPGV 127 GL A G A TPR RLLA+FD + + RGC F N+ E P V Sbjct 62 TGLEAAVGAA--------TTPRGRLLAVFDYLDAWFREDDFRGCAFINSFGELGASSPAV 113 Query 128 ERIVHSHKRDYIKGLARLAREAGAAHPRSLGNQLAVLFEGAAALSTSLDDAGPWAHARAA 187 +V + K + L AR AG P ++G QLA+L EGA + D AR A Sbjct 114 ADVVRTQKATFQAQLRERARAAGL--PDAVGAQLAILAEGAQTTAAISGDPAAAGQARDA 171 Query 188 AEVLIDQATARPV 200 AE+LID A AR V Sbjct 172 AELLIDAALARRV 184 >gi|170695791|ref|ZP_02886933.1| transcriptional regulator, TetR family [Burkholderia graminis C4D1M] gi|170139396|gb|EDT07582.1| transcriptional regulator, TetR family [Burkholderia graminis C4D1M] Length=223 Score = 92.8 bits (229), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 65/177 (37%), Positives = 88/177 (50%), Gaps = 7/177 (3%) Query 3 PVTRTTEPPRRGGRGARQRILKAAAELFYCEGINATGVELIANKASVSKRTLYQHFPSKS 62 P +R + G A+Q +L+AA ELFY +G+ A GV+ + +A V+K +LY+ F SK Sbjct 20 PASRRVRATQTTGPEAQQHLLRAADELFYRDGVRAVGVDAVVERAGVNKMSLYRQFSSKD 79 Query 63 ALVEEYL-RGLRQAAGEADKMPKASNATPRERLLALFD----RPNRGDGRMRGCPFHNAA 117 LV YL R Q G +K P ++L FD R + D RGCPF N A Sbjct 80 ELVMAYLERKDAQFFGYVEKSFAKHPGEPAKQLQQYFDDLAARASLED--YRGCPFVNVA 137 Query 118 VEAAGEMPGVERIVHSHKRDYIKGLARLAREAGAAHPRSLGNQLAVLFEGAAALSTS 174 VE + + V +K + L LA AGA P L N LA+L EG A S + Sbjct 138 VEFSDTEHAARQFVFRNKERLLARLTELATAAGADDPEMLANALALLIEGVYAASQT 194 >gi|312795890|ref|YP_004028812.1| transcriptional regulator, TetR family [Burkholderia rhizoxinica HKI 454] gi|312167665|emb|CBW74668.1| Transcriptional regulator, TetR family [Burkholderia rhizoxinica HKI 454] Length=219 Score = 92.8 bits (229), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 70/195 (36%), Positives = 97/195 (50%), Gaps = 18/195 (9%) Query 14 GGRGARQRILKAAAELFYCEGINATGVELIANKASVSKRTLYQHFPSKSALVEEYLRGLR 73 G A+Q++L AAA LFY +GI A G++ + +A V+K +LY+ F SK LV YL + Sbjct 25 AGADAQQQLLDAAARLFYAQGIRAVGIDAVVEQAGVNKMSLYRQFASKDELVVAYLNRMD 84 Query 74 QAAGEADKMPKASN-ATPRERLLALFD----RPNRGDGRMRGCPFHNAAVEAAGEMPGVE 128 + + A + P +L F+ R R D RGCPF N + E + Sbjct 85 AEYWQRFECSTAQHPGQPARQLKQFFEDLTARARRPD--YRGCPFVNVSCEFSDRDHPAR 142 Query 129 RIVHSHKRDYIKGLARLAREAGAAHPRSLGNQLAVLFEGAAALSTSLD------DAGPWA 182 +IV +K ++ L LAR+AGA P LG LA+L EG S + D D+ P Sbjct 143 QIVARNKTALLERLTDLARQAGAHEPARLGASLALLVEGVYTASQTFDPRCDIIDSAP-- 200 Query 183 HARAAAEVLIDQATA 197 A A LID ATA Sbjct 201 ---ALAAQLIDAATA 212 >gi|333919849|ref|YP_004493430.1| putative TetR family transcriptional regulator [Amycolicicoccus subflavus DQS3-9A1] gi|333482070|gb|AEF40630.1| putative transcriptional regulator, TetR family protein [Amycolicicoccus subflavus DQS3-9A1] Length=189 Score = 92.8 bits (229), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 71/178 (40%), Positives = 91/178 (52%), Gaps = 6/178 (3%) Query 25 AAAELFYCEGINATGVELIANKASVSKRTLYQHFPSKSALVEEYLRGL-RQAAGEADKMP 83 AAAELFY EGI A GV + +A+ TLY+HF SK L+E +L R+ + + Sbjct 2 AAAELFYTEGIRAIGVNRLLEEANTPIMTLYRHFGSKDGLIEAFLADKDRRVRAKFARAV 61 Query 84 KASNATPRERLLALFDRPNR--GDGRMRGCPFHNAAVEAA-GEMPGVERIVHSHKRDYIK 140 + + T RER+LA+FD D + RGC F N AVE A E P V+ I SHK + Sbjct 62 ERTGTTGRERVLAMFDALGHVITDPKYRGCTFINVAVEMADAEHPFVD-IAVSHKNFVRE 120 Query 141 GLARLAREAGAAHPRSLGNQLAVLFEGAAALSTSLDDAGPWA-HARAAAEVLIDQATA 197 AR EAG L QL +L G + D A AR AAEVL++ A A Sbjct 121 TFARHLTEAGVRDAEPLATQLLILMNGVFVSAQIYPDGTETAKQARMAAEVLLNAALA 178 >gi|300786039|ref|YP_003766330.1| TetR family transcriptional regulator [Amycolatopsis mediterranei U32] gi|299795553|gb|ADJ45928.1| TetR family transcriptional regulator [Amycolatopsis mediterranei U32] gi|340527504|gb|AEK42709.1| TetR family transcriptional regulator [Amycolatopsis mediterranei S699] Length=189 Score = 92.8 bits (229), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 67/177 (38%), Positives = 93/177 (53%), Gaps = 7/177 (3%) Query 21 RILKAAAELFYCEGINATGVELIANKASVSKRTLYQHFPSKSALVEEYLRGL-RQAAGEA 79 ++LKAA+ LFY +GI+A GV+ +A +A V+K LY +F SKS LV YLR R+ E Sbjct 12 KVLKAASTLFYRDGIHAVGVDTVAAEAGVTKAALYGNFGSKSGLVVAYLRERDRRWQEEV 71 Query 80 DKMPKASNATPRERLLALFDRPNRGDGR--MRGCPFHNAAVEAAGEMPGVERIVHSHK-- 135 D++ A++A PRER+LA+FD R RGC F NAA E V +V HK Sbjct 72 DRI-TAAHADPRERVLAVFDAYEAWLSRDGYRGCAFQNAASEFPDPADPVREVVRHHKTA 130 Query 136 -RDYIKGLARLAREAGAAHPRSLGNQLAVLFEGAAALSTSLDDAGPWAHARAAAEVL 191 Y++ R +L ++L +L EGA A S P+ A+ A L Sbjct 131 LHGYLRAQLRRGDRGDPERADALADELMLLLEGATATSVVAQGPQPFETAKRLARTL 187 >gi|337746528|ref|YP_004640690.1| transcriptional regulator [Paenibacillus mucilaginosus KNP414] gi|336297717|gb|AEI40820.1| Transcriptional regulator [Paenibacillus mucilaginosus KNP414] Length=194 Score = 92.4 bits (228), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 65/180 (37%), Positives = 88/180 (49%), Gaps = 4/180 (2%) Query 17 GARQRILKAAAELFYCEGINATGVELIANKASVSKRTLYQHFPSKSALVEEYLRGLRQAA 76 RQ IL A+ELFY EGI + GV+ I ++ VSK TLY+HFP+K L+ YL Sbjct 6 SVRQHILNVASELFYREGIRSVGVDTIVERSEVSKATLYRHFPTKDDLIIAYLEAQDHIN 65 Query 77 G-EADKMPKASNATPRERLLALFDRPNR--GDGRMRGCPFHNAAVEAAGEMPGVERIVHS 133 D+ P+E+LLAL D G RGC F NA E + E V + Sbjct 66 WVHFDEAVAKHEGCPKEQLLALIDATIELLEPGYHRGCAFLNALAEFSEEDHPVHLLAVE 125 Query 134 HKRDYIKGLARLAREAGAAHPRSLGNQLAVLFEGAAALSTSLDDAGPWAHARAAAEVLID 193 + R ++RL+++AG R L +QL ++ GA A +GP A A LID Sbjct 126 YNRALRLRISRLSQKAGVQDER-LTDQLMLVINGALASVPVYGLSGPAAELTTVARYLID 184 >gi|344997753|ref|YP_004800607.1| TetR family transcriptional regulator [Streptomyces sp. SirexAA-E] gi|344313379|gb|AEN08067.1| transcriptional regulator, TetR family [Streptomyces sp. SirexAA-E] Length=203 Score = 92.4 bits (228), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 61/166 (37%), Positives = 87/166 (53%), Gaps = 5/166 (3%) Query 19 RQRILKAAAELFYCEGINATGVELIANKASVSKRTLYQHFPSKSALVEEYLRGLRQAAGE 78 R+RIL AA ELF EGI A GV+ IA++A +K LY+HF +K ALVE++LR + Sbjct 16 RERILDAAEELFAREGIKAVGVQAIADRAETTKMALYRHFATKDALVEQWLRIVAADYTA 75 Query 79 A-DKMPKASNATPRERLLAL--FDRPNRGDGRMRGCPFHNAAVEAAGEMPGVERIVHSHK 135 A D++ A PR ++L L F + RGCPF N+ E R++ HK Sbjct 76 AFDRLEAAHPDDPRAQILGLARFIADGLSEISHRGCPFINSIAELPDRTHPARRLIEDHK 135 Query 136 RDYIKGLARLAREAGAAHPRSLGNQLAVLFEGA--AALSTSLDDAG 179 D + L L AG + P ++ + EGA +A + S+D G Sbjct 136 ADQARRLTALCVRAGLSGPDEAAAEITFVLEGAQVSAQNGSIDQVG 181 >gi|118466289|ref|YP_880488.1| transcriptional regulator [Mycobacterium avium 104] gi|118167576|gb|ABK68473.1| transcriptional regulator [Mycobacterium avium 104] Length=201 Score = 92.4 bits (228), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 76/171 (45%), Positives = 94/171 (55%), Gaps = 4/171 (2%) Query 22 ILKAAAELFYCEGINATGVELIANKASVSKRTLYQHFPSKSALVEEYLRGLRQAAGEADK 81 IL AA +LF GIN TG++L+ A VSKRT YQHF SK L+ EYLR R + Sbjct 24 ILGAAQQLFRERGINNTGMDLLCAAAQVSKRTAYQHFGSKDELIAEYLR--RLDVDTTSE 81 Query 82 MPKASNATPRERLLALFDR-PNRGDGRMRGCPFHNAAVEAAGEMPGVERIVHSHKRDYIK 140 + + + TPRERLLA+F P D M CPF AAVE + +K Sbjct 82 VFERDDLTPRERLLAVFATPPAFTDEPMPLCPFIAAAVEISDPQHPARVRAREYKTSVAA 141 Query 141 GLARLAREAGAAHPRSLGNQLAVLFEGAAALSTSL-DDAGPWAHARAAAEV 190 L+ AREAGAA P LG QLA+L +GA+ + +L DA P A AAA V Sbjct 142 RLSETAREAGAADPELLGEQLALLLDGASVRTRALGSDAFPTAAGIAAALV 192 >gi|339053310|ref|ZP_08648047.1| Transcriptional regulator2C TetR family [gamma proteobacterium IMCC2047] gi|330721481|gb|EGG99528.1| Transcriptional regulator2C TetR family [gamma proteobacterium IMCC2047] Length=193 Score = 92.0 bits (227), Expect = 5e-17, Method: Compositional matrix adjust. Identities = 63/178 (36%), Positives = 96/178 (54%), Gaps = 17/178 (9%) Query 8 TEPPRRGGRGARQRILKAAAELFYCEGINATGVELIANKASVSKRTLYQHFPSKSALVEE 67 T PP + R++++ A LF G +ATG++LIA ++ V+KRTLY HF SK LV Sbjct 4 TPPPSK-----REQLIHTALTLFSRYGFHATGIDLIAKESGVTKRTLYAHFGSKDELVVA 58 Query 68 YLRGL-RQAAGEADKMPKASNATPRERLLALFDRPN--RGDGRMRGCPFHNAAVEAAGEM 124 LR L Q K ++ P++RLL++FD + GC F NA E A Sbjct 59 TLRHLDEQLRSYFLKHTNSTCEDPKQRLLSVFDAAGFWFSEDNFFGCTFINAIGEYAESN 118 Query 125 PGVERIVHSHK---RDYIKGLARLAREAGAAHPRSLGNQLAVLFEGA---AALSTSLD 176 + ++ +K R++IKG L +AGA +P+ L ++L+++ EGA A +S LD Sbjct 119 DSIRQVCSEYKRLSREWIKG---LCEQAGAPNPQQLSDELSLILEGAIVTAQVSPQLD 173 Lambda K H 0.318 0.132 0.385 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 218250040016 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40