BLASTP 2.2.25+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.



Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
           15,229,318 sequences; 5,219,829,388 total letters



Query= Rv3220c

Length=501
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

gi|15610356|ref|NP_217736.1|  two component sensor kinase [Mycoba...   994    0.0   
gi|31794398|ref|NP_856891.1|  two component sensor kinase [Mycoba...   992    0.0   
gi|148824419|ref|YP_001289173.1|  two component sensor kinase [My...   991    0.0   
gi|289448906|ref|ZP_06438650.1|  two component system sensor kina...   991    0.0   
gi|289747036|ref|ZP_06506414.1|  two component sensor kinase [Myc...   991    0.0   
gi|306782267|ref|ZP_07420604.1|  two component system sensor kina...   988    0.0   
gi|289751910|ref|ZP_06511288.1|  signal transduction histidine ki...   915    0.0   
gi|240170390|ref|ZP_04749049.1|  sensor kinase from two-component...   834    0.0   
gi|183981360|ref|YP_001849651.1|  sensor kinase from two-componen...   832    0.0   
gi|118618024|ref|YP_906356.1|  sensor kinase from two component r...   831    0.0   
gi|254776607|ref|ZP_05218123.1|  sensor histidine kinase [Mycobac...   827    0.0   
gi|118466753|ref|YP_883315.1|  sensor histidine kinase [Mycobacte...   826    0.0   
gi|41409419|ref|NP_962255.1|  hypothetical protein MAP3321c [Myco...   825    0.0   
gi|342861178|ref|ZP_08717827.1|  sensor histidine kinase [Mycobac...   821    0.0   
gi|296169003|ref|ZP_06850669.1|  sensor histidine kinase [Mycobac...   818    0.0   
gi|254819136|ref|ZP_05224137.1|  sensor histidine kinase [Mycobac...   818    0.0   
gi|15827350|ref|NP_301613.1|  two-component system sensor kinase ...   806    0.0   
gi|108798353|ref|YP_638550.1|  signal transduction histidine kina...   752    0.0   
gi|126434018|ref|YP_001069709.1|  signal transduction histidine k...   752    0.0   
gi|315445561|ref|YP_004078440.1|  signal transduction histidine k...   736    0.0   
gi|120402780|ref|YP_952609.1|  signal transduction histidine kina...   735    0.0   
gi|145225264|ref|YP_001135942.1|  signal transduction histidine k...   735    0.0   
gi|118468520|ref|YP_886284.1|  sensor histidine kinase [Mycobacte...   731    0.0   
gi|333991573|ref|YP_004524187.1|  sensor kinase from two-componen...   701    0.0   
gi|169630621|ref|YP_001704270.1|  two component sensor kinase [My...   701    0.0   
gi|111023307|ref|YP_706279.1|  histidine kinase [Rhodococcus jost...   590    2e-166
gi|226365814|ref|YP_002783597.1|  two-component histidine kinase ...   589    4e-166
gi|312140652|ref|YP_004007988.1|  two component system sensor kin...   577    2e-162
gi|229489533|ref|ZP_04383396.1|  sensor histidine kinase [Rhodoco...   570    2e-160
gi|226305676|ref|YP_002765636.1|  two-component histidine kinase ...   570    2e-160
gi|54026554|ref|YP_120796.1|  putative two-component system senso...   570    3e-160
gi|333921431|ref|YP_004495012.1|  putative two-component histidin...   561    9e-158
gi|300789788|ref|YP_003770079.1|  two-component system sensor kin...   488    9e-136
gi|134102861|ref|YP_001108522.1|  putative two-component system s...   484    1e-134
gi|302529993|ref|ZP_07282335.1|  histidine kinase [Streptomyces s...   483    4e-134
gi|256380280|ref|YP_003103940.1|  signal transduction histidine k...   482    6e-134
gi|257057041|ref|YP_003134873.1|  signal transduction histidine k...   476    3e-132
gi|296138837|ref|YP_003646080.1|  signal transduction histidine k...   467    2e-129
gi|258651645|ref|YP_003200801.1|  signal transduction histidine k...   459    7e-127
gi|343927611|ref|ZP_08767079.1|  putative two-component histidine...   456    4e-126
gi|331698905|ref|YP_004335144.1|  signal transduction histidine k...   450    3e-124
gi|262203400|ref|YP_003274608.1|  histidine kinase dimerization/p...   446    5e-123
gi|291302627|ref|YP_003513905.1|  signal transduction histidine k...   417    3e-114
gi|324998110|ref|ZP_08119222.1|  signal transduction histidine ki...   414    2e-113
gi|326383292|ref|ZP_08204980.1|  histidine kinase dimerization/ph...   412    7e-113
gi|330469940|ref|YP_004407683.1|  histidine kinase dimerization/p...   411    1e-112
gi|302869691|ref|YP_003838328.1|  histidine kinase dimerization/p...   405    7e-111
gi|315503827|ref|YP_004082714.1|  signal transduction histidine k...   404    2e-110
gi|317508056|ref|ZP_07965742.1|  histidine kinase [Segniliparus r...   403    4e-110
gi|284033089|ref|YP_003383020.1|  signal transduction histidine k...   402    7e-110


>gi|15610356|ref|NP_217736.1| two component sensor kinase [Mycobacterium tuberculosis H37Rv]
 gi|15842807|ref|NP_337844.1| sensor histidine kinase [Mycobacterium tuberculosis CDC1551]
 gi|148663081|ref|YP_001284604.1| putative two component sensor kinase [Mycobacterium tuberculosis 
H37Ra]
 42 more sequence titles
 Length=501

 Score =  994 bits (2570),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 501/501 (100%), Positives = 501/501 (100%), Gaps = 0/501 (0%)

Query  1    MSTLGDLLAEHTVLPGSAVDHLHAVVGEWQLLADLSFADYLMWVRRDDGVLVCVAQCRPN  60
            MSTLGDLLAEHTVLPGSAVDHLHAVVGEWQLLADLSFADYLMWVRRDDGVLVCVAQCRPN
Sbjct  1    MSTLGDLLAEHTVLPGSAVDHLHAVVGEWQLLADLSFADYLMWVRRDDGVLVCVAQCRPN  60

Query  61   TGPTVVHTDAVGTVVAANSMPLVAATFSGGVPGREGAVGQQNSCQHDGHSVEVSPVRFGD  120
            TGPTVVHTDAVGTVVAANSMPLVAATFSGGVPGREGAVGQQNSCQHDGHSVEVSPVRFGD
Sbjct  61   TGPTVVHTDAVGTVVAANSMPLVAATFSGGVPGREGAVGQQNSCQHDGHSVEVSPVRFGD  120

Query  121  QVVAVLTRHQPELAARRRSGHLETAYRLCATDLLRMLAEGTFPDAGDVAMSRSSPRAGDG  180
            QVVAVLTRHQPELAARRRSGHLETAYRLCATDLLRMLAEGTFPDAGDVAMSRSSPRAGDG
Sbjct  121  QVVAVLTRHQPELAARRRSGHLETAYRLCATDLLRMLAEGTFPDAGDVAMSRSSPRAGDG  180

Query  181  FIRLDVDGVVSYASPNALSAYHRMGLTTELEGVNLIDATRPLISDPFEAHEVDEHVQDLL  240
            FIRLDVDGVVSYASPNALSAYHRMGLTTELEGVNLIDATRPLISDPFEAHEVDEHVQDLL
Sbjct  181  FIRLDVDGVVSYASPNALSAYHRMGLTTELEGVNLIDATRPLISDPFEAHEVDEHVQDLL  240

Query  241  AGDGKGMRMEVDAGGATVLLRTLPLVVAGRNVGAAILIRDVTEVKRRDRALISKDATIRE  300
            AGDGKGMRMEVDAGGATVLLRTLPLVVAGRNVGAAILIRDVTEVKRRDRALISKDATIRE
Sbjct  241  AGDGKGMRMEVDAGGATVLLRTLPLVVAGRNVGAAILIRDVTEVKRRDRALISKDATIRE  300

Query  301  IHHRVKNNLQTVAALLRLQARRTSNAEGREALIESVRRVSSIALVHDALSMSVDEQVNLD  360
            IHHRVKNNLQTVAALLRLQARRTSNAEGREALIESVRRVSSIALVHDALSMSVDEQVNLD
Sbjct  301  IHHRVKNNLQTVAALLRLQARRTSNAEGREALIESVRRVSSIALVHDALSMSVDEQVNLD  360

Query  361  EVIDRILPIMNDVASVDRPIRINRVGDLGVLDSDRATALIMVITELVQNAIEHAFDPAAA  420
            EVIDRILPIMNDVASVDRPIRINRVGDLGVLDSDRATALIMVITELVQNAIEHAFDPAAA
Sbjct  361  EVIDRILPIMNDVASVDRPIRINRVGDLGVLDSDRATALIMVITELVQNAIEHAFDPAAA  420

Query  421  EGSVTIRAERSARWLDVVVHDDGLGLPQGFSLEKSDSLGLQIVRTLVSAELDGSLGMRDA  480
            EGSVTIRAERSARWLDVVVHDDGLGLPQGFSLEKSDSLGLQIVRTLVSAELDGSLGMRDA
Sbjct  421  EGSVTIRAERSARWLDVVVHDDGLGLPQGFSLEKSDSLGLQIVRTLVSAELDGSLGMRDA  480

Query  481  RERGTDVVLRVPVGRRGRLML  501
            RERGTDVVLRVPVGRRGRLML
Sbjct  481  RERGTDVVLRVPVGRRGRLML  501


>gi|31794398|ref|NP_856891.1| two component sensor kinase [Mycobacterium bovis AF2122/97]
 gi|121639107|ref|YP_979331.1| putative two component sensor kinase [Mycobacterium bovis BCG 
str. Pasteur 1173P2]
 gi|121639199|ref|YP_979423.1| putative two component sensor kinase [Mycobacterium bovis BCG 
str. Pasteur 1173P2]
 6 more sequence titles
 Length=501

 Score =  992 bits (2565),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 500/501 (99%), Positives = 501/501 (100%), Gaps = 0/501 (0%)

Query  1    MSTLGDLLAEHTVLPGSAVDHLHAVVGEWQLLADLSFADYLMWVRRDDGVLVCVAQCRPN  60
            MSTLGDLLAEHTVLPGSAVDHLHAVVGEWQLLADLSFADYLMWVRR+DGVLVCVAQCRPN
Sbjct  1    MSTLGDLLAEHTVLPGSAVDHLHAVVGEWQLLADLSFADYLMWVRRNDGVLVCVAQCRPN  60

Query  61   TGPTVVHTDAVGTVVAANSMPLVAATFSGGVPGREGAVGQQNSCQHDGHSVEVSPVRFGD  120
            TGPTVVHTDAVGTVVAANSMPLVAATFSGGVPGREGAVGQQNSCQHDGHSVEVSPVRFGD
Sbjct  61   TGPTVVHTDAVGTVVAANSMPLVAATFSGGVPGREGAVGQQNSCQHDGHSVEVSPVRFGD  120

Query  121  QVVAVLTRHQPELAARRRSGHLETAYRLCATDLLRMLAEGTFPDAGDVAMSRSSPRAGDG  180
            QVVAVLTRHQPELAARRRSGHLETAYRLCATDLLRMLAEGTFPDAGDVAMSRSSPRAGDG
Sbjct  121  QVVAVLTRHQPELAARRRSGHLETAYRLCATDLLRMLAEGTFPDAGDVAMSRSSPRAGDG  180

Query  181  FIRLDVDGVVSYASPNALSAYHRMGLTTELEGVNLIDATRPLISDPFEAHEVDEHVQDLL  240
            FIRLDVDGVVSYASPNALSAYHRMGLTTELEGVNLIDATRPLISDPFEAHEVDEHVQDLL
Sbjct  181  FIRLDVDGVVSYASPNALSAYHRMGLTTELEGVNLIDATRPLISDPFEAHEVDEHVQDLL  240

Query  241  AGDGKGMRMEVDAGGATVLLRTLPLVVAGRNVGAAILIRDVTEVKRRDRALISKDATIRE  300
            AGDGKGMRMEVDAGGATVLLRTLPLVVAGRNVGAAILIRDVTEVKRRDRALISKDATIRE
Sbjct  241  AGDGKGMRMEVDAGGATVLLRTLPLVVAGRNVGAAILIRDVTEVKRRDRALISKDATIRE  300

Query  301  IHHRVKNNLQTVAALLRLQARRTSNAEGREALIESVRRVSSIALVHDALSMSVDEQVNLD  360
            IHHRVKNNLQTVAALLRLQARRTSNAEGREALIESVRRVSSIALVHDALSMSVDEQVNLD
Sbjct  301  IHHRVKNNLQTVAALLRLQARRTSNAEGREALIESVRRVSSIALVHDALSMSVDEQVNLD  360

Query  361  EVIDRILPIMNDVASVDRPIRINRVGDLGVLDSDRATALIMVITELVQNAIEHAFDPAAA  420
            EVIDRILPIMNDVASVDRPIRINRVGDLGVLDSDRATALIMVITELVQNAIEHAFDPAAA
Sbjct  361  EVIDRILPIMNDVASVDRPIRINRVGDLGVLDSDRATALIMVITELVQNAIEHAFDPAAA  420

Query  421  EGSVTIRAERSARWLDVVVHDDGLGLPQGFSLEKSDSLGLQIVRTLVSAELDGSLGMRDA  480
            EGSVTIRAERSARWLDVVVHDDGLGLPQGFSLEKSDSLGLQIVRTLVSAELDGSLGMRDA
Sbjct  421  EGSVTIRAERSARWLDVVVHDDGLGLPQGFSLEKSDSLGLQIVRTLVSAELDGSLGMRDA  480

Query  481  RERGTDVVLRVPVGRRGRLML  501
            RERGTDVVLRVPVGRRGRLML
Sbjct  481  RERGTDVVLRVPVGRRGRLML  501


>gi|148824419|ref|YP_001289173.1| two component sensor kinase [Mycobacterium tuberculosis F11]
 gi|148722946|gb|ABR07571.1| two component sensor kinase [Mycobacterium tuberculosis F11]
Length=501

 Score =  991 bits (2563),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 500/501 (99%), Positives = 500/501 (99%), Gaps = 0/501 (0%)

Query  1    MSTLGDLLAEHTVLPGSAVDHLHAVVGEWQLLADLSFADYLMWVRRDDGVLVCVAQCRPN  60
            MSTLGDLLAEHTVLPGSAVDHLHAVVGEWQLLADLSFADYLMWVRRDDGVLVCVAQCRPN
Sbjct  1    MSTLGDLLAEHTVLPGSAVDHLHAVVGEWQLLADLSFADYLMWVRRDDGVLVCVAQCRPN  60

Query  61   TGPTVVHTDAVGTVVAANSMPLVAATFSGGVPGREGAVGQQNSCQHDGHSVEVSPVRFGD  120
            TGPTVVHTDAVGTVVAANSMPLVAATFSGGVPGREGAVGQ NSCQHDGHSVEVSPVRFGD
Sbjct  61   TGPTVVHTDAVGTVVAANSMPLVAATFSGGVPGREGAVGQHNSCQHDGHSVEVSPVRFGD  120

Query  121  QVVAVLTRHQPELAARRRSGHLETAYRLCATDLLRMLAEGTFPDAGDVAMSRSSPRAGDG  180
            QVVAVLTRHQPELAARRRSGHLETAYRLCATDLLRMLAEGTFPDAGDVAMSRSSPRAGDG
Sbjct  121  QVVAVLTRHQPELAARRRSGHLETAYRLCATDLLRMLAEGTFPDAGDVAMSRSSPRAGDG  180

Query  181  FIRLDVDGVVSYASPNALSAYHRMGLTTELEGVNLIDATRPLISDPFEAHEVDEHVQDLL  240
            FIRLDVDGVVSYASPNALSAYHRMGLTTELEGVNLIDATRPLISDPFEAHEVDEHVQDLL
Sbjct  181  FIRLDVDGVVSYASPNALSAYHRMGLTTELEGVNLIDATRPLISDPFEAHEVDEHVQDLL  240

Query  241  AGDGKGMRMEVDAGGATVLLRTLPLVVAGRNVGAAILIRDVTEVKRRDRALISKDATIRE  300
            AGDGKGMRMEVDAGGATVLLRTLPLVVAGRNVGAAILIRDVTEVKRRDRALISKDATIRE
Sbjct  241  AGDGKGMRMEVDAGGATVLLRTLPLVVAGRNVGAAILIRDVTEVKRRDRALISKDATIRE  300

Query  301  IHHRVKNNLQTVAALLRLQARRTSNAEGREALIESVRRVSSIALVHDALSMSVDEQVNLD  360
            IHHRVKNNLQTVAALLRLQARRTSNAEGREALIESVRRVSSIALVHDALSMSVDEQVNLD
Sbjct  301  IHHRVKNNLQTVAALLRLQARRTSNAEGREALIESVRRVSSIALVHDALSMSVDEQVNLD  360

Query  361  EVIDRILPIMNDVASVDRPIRINRVGDLGVLDSDRATALIMVITELVQNAIEHAFDPAAA  420
            EVIDRILPIMNDVASVDRPIRINRVGDLGVLDSDRATALIMVITELVQNAIEHAFDPAAA
Sbjct  361  EVIDRILPIMNDVASVDRPIRINRVGDLGVLDSDRATALIMVITELVQNAIEHAFDPAAA  420

Query  421  EGSVTIRAERSARWLDVVVHDDGLGLPQGFSLEKSDSLGLQIVRTLVSAELDGSLGMRDA  480
            EGSVTIRAERSARWLDVVVHDDGLGLPQGFSLEKSDSLGLQIVRTLVSAELDGSLGMRDA
Sbjct  421  EGSVTIRAERSARWLDVVVHDDGLGLPQGFSLEKSDSLGLQIVRTLVSAELDGSLGMRDA  480

Query  481  RERGTDVVLRVPVGRRGRLML  501
            RERGTDVVLRVPVGRRGRLML
Sbjct  481  RERGTDVVLRVPVGRRGRLML  501


>gi|289448906|ref|ZP_06438650.1| two component system sensor kinase [Mycobacterium tuberculosis 
CPHL_A]
 gi|289421864|gb|EFD19065.1| two component system sensor kinase [Mycobacterium tuberculosis 
CPHL_A]
Length=501

 Score =  991 bits (2561),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 500/501 (99%), Positives = 500/501 (99%), Gaps = 0/501 (0%)

Query  1    MSTLGDLLAEHTVLPGSAVDHLHAVVGEWQLLADLSFADYLMWVRRDDGVLVCVAQCRPN  60
            MSTLGDLLAEHTVLPGSAVDHLHAVVGEWQLLADLSFADYLMWVRRDDGVLVCVAQCRPN
Sbjct  1    MSTLGDLLAEHTVLPGSAVDHLHAVVGEWQLLADLSFADYLMWVRRDDGVLVCVAQCRPN  60

Query  61   TGPTVVHTDAVGTVVAANSMPLVAATFSGGVPGREGAVGQQNSCQHDGHSVEVSPVRFGD  120
            TGPTVVHTDAVGTVVAANSMPLVAATFSGGVPGREGAVGQQNSCQHDGHSVEVSPVRFGD
Sbjct  61   TGPTVVHTDAVGTVVAANSMPLVAATFSGGVPGREGAVGQQNSCQHDGHSVEVSPVRFGD  120

Query  121  QVVAVLTRHQPELAARRRSGHLETAYRLCATDLLRMLAEGTFPDAGDVAMSRSSPRAGDG  180
            QVVAVLTRHQPELAARRRSGHLETAYRLCATDLLRMLAEGTFPDAGDVAMSRSSPRAGDG
Sbjct  121  QVVAVLTRHQPELAARRRSGHLETAYRLCATDLLRMLAEGTFPDAGDVAMSRSSPRAGDG  180

Query  181  FIRLDVDGVVSYASPNALSAYHRMGLTTELEGVNLIDATRPLISDPFEAHEVDEHVQDLL  240
            FIRLDVDGVVSYASPNALSAYHRMGLTTELEGVNLIDATRPLISDPFEAHEVDEHVQDLL
Sbjct  181  FIRLDVDGVVSYASPNALSAYHRMGLTTELEGVNLIDATRPLISDPFEAHEVDEHVQDLL  240

Query  241  AGDGKGMRMEVDAGGATVLLRTLPLVVAGRNVGAAILIRDVTEVKRRDRALISKDATIRE  300
            AGDGKGMRMEVDAGGATVLLRTLPLVVAGRNVGAAILIRDVTEVKRRDRALISKDATIRE
Sbjct  241  AGDGKGMRMEVDAGGATVLLRTLPLVVAGRNVGAAILIRDVTEVKRRDRALISKDATIRE  300

Query  301  IHHRVKNNLQTVAALLRLQARRTSNAEGREALIESVRRVSSIALVHDALSMSVDEQVNLD  360
            IHHRVKNNLQTVAALLRLQARRTSNAEGREALIESVRRVSSIALVHDALSMSVDEQVNLD
Sbjct  301  IHHRVKNNLQTVAALLRLQARRTSNAEGREALIESVRRVSSIALVHDALSMSVDEQVNLD  360

Query  361  EVIDRILPIMNDVASVDRPIRINRVGDLGVLDSDRATALIMVITELVQNAIEHAFDPAAA  420
            EVIDRILPIMNDVASVDRPIRINRVGDLGVLDS RATALIMVITELVQNAIEHAFDPAAA
Sbjct  361  EVIDRILPIMNDVASVDRPIRINRVGDLGVLDSGRATALIMVITELVQNAIEHAFDPAAA  420

Query  421  EGSVTIRAERSARWLDVVVHDDGLGLPQGFSLEKSDSLGLQIVRTLVSAELDGSLGMRDA  480
            EGSVTIRAERSARWLDVVVHDDGLGLPQGFSLEKSDSLGLQIVRTLVSAELDGSLGMRDA
Sbjct  421  EGSVTIRAERSARWLDVVVHDDGLGLPQGFSLEKSDSLGLQIVRTLVSAELDGSLGMRDA  480

Query  481  RERGTDVVLRVPVGRRGRLML  501
            RERGTDVVLRVPVGRRGRLML
Sbjct  481  RERGTDVVLRVPVGRRGRLML  501


>gi|289747036|ref|ZP_06506414.1| two component sensor kinase [Mycobacterium tuberculosis 02_1987]
 gi|289759356|ref|ZP_06518734.1| two component sensor kinase [Mycobacterium tuberculosis T85]
 gi|294993256|ref|ZP_06798947.1| two component system sensor kinase [Mycobacterium tuberculosis 
210]
 7 more sequence titles
 Length=501

 Score =  991 bits (2561),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 500/501 (99%), Positives = 500/501 (99%), Gaps = 0/501 (0%)

Query  1    MSTLGDLLAEHTVLPGSAVDHLHAVVGEWQLLADLSFADYLMWVRRDDGVLVCVAQCRPN  60
            MSTLGDLLAEHTVLPGSAVDHLHAVVGEWQLLADLSFADYLMWVRRDDGVLVCVAQCRPN
Sbjct  1    MSTLGDLLAEHTVLPGSAVDHLHAVVGEWQLLADLSFADYLMWVRRDDGVLVCVAQCRPN  60

Query  61   TGPTVVHTDAVGTVVAANSMPLVAATFSGGVPGREGAVGQQNSCQHDGHSVEVSPVRFGD  120
            TGPTVVHTDAVGTVVAANSMPLVAATFSGGVPGRE AVGQQNSCQHDGHSVEVSPVRFGD
Sbjct  61   TGPTVVHTDAVGTVVAANSMPLVAATFSGGVPGRERAVGQQNSCQHDGHSVEVSPVRFGD  120

Query  121  QVVAVLTRHQPELAARRRSGHLETAYRLCATDLLRMLAEGTFPDAGDVAMSRSSPRAGDG  180
            QVVAVLTRHQPELAARRRSGHLETAYRLCATDLLRMLAEGTFPDAGDVAMSRSSPRAGDG
Sbjct  121  QVVAVLTRHQPELAARRRSGHLETAYRLCATDLLRMLAEGTFPDAGDVAMSRSSPRAGDG  180

Query  181  FIRLDVDGVVSYASPNALSAYHRMGLTTELEGVNLIDATRPLISDPFEAHEVDEHVQDLL  240
            FIRLDVDGVVSYASPNALSAYHRMGLTTELEGVNLIDATRPLISDPFEAHEVDEHVQDLL
Sbjct  181  FIRLDVDGVVSYASPNALSAYHRMGLTTELEGVNLIDATRPLISDPFEAHEVDEHVQDLL  240

Query  241  AGDGKGMRMEVDAGGATVLLRTLPLVVAGRNVGAAILIRDVTEVKRRDRALISKDATIRE  300
            AGDGKGMRMEVDAGGATVLLRTLPLVVAGRNVGAAILIRDVTEVKRRDRALISKDATIRE
Sbjct  241  AGDGKGMRMEVDAGGATVLLRTLPLVVAGRNVGAAILIRDVTEVKRRDRALISKDATIRE  300

Query  301  IHHRVKNNLQTVAALLRLQARRTSNAEGREALIESVRRVSSIALVHDALSMSVDEQVNLD  360
            IHHRVKNNLQTVAALLRLQARRTSNAEGREALIESVRRVSSIALVHDALSMSVDEQVNLD
Sbjct  301  IHHRVKNNLQTVAALLRLQARRTSNAEGREALIESVRRVSSIALVHDALSMSVDEQVNLD  360

Query  361  EVIDRILPIMNDVASVDRPIRINRVGDLGVLDSDRATALIMVITELVQNAIEHAFDPAAA  420
            EVIDRILPIMNDVASVDRPIRINRVGDLGVLDSDRATALIMVITELVQNAIEHAFDPAAA
Sbjct  361  EVIDRILPIMNDVASVDRPIRINRVGDLGVLDSDRATALIMVITELVQNAIEHAFDPAAA  420

Query  421  EGSVTIRAERSARWLDVVVHDDGLGLPQGFSLEKSDSLGLQIVRTLVSAELDGSLGMRDA  480
            EGSVTIRAERSARWLDVVVHDDGLGLPQGFSLEKSDSLGLQIVRTLVSAELDGSLGMRDA
Sbjct  421  EGSVTIRAERSARWLDVVVHDDGLGLPQGFSLEKSDSLGLQIVRTLVSAELDGSLGMRDA  480

Query  481  RERGTDVVLRVPVGRRGRLML  501
            RERGTDVVLRVPVGRRGRLML
Sbjct  481  RERGTDVVLRVPVGRRGRLML  501


>gi|306782267|ref|ZP_07420604.1| two component system sensor kinase [Mycobacterium tuberculosis 
SUMu002]
 gi|306786090|ref|ZP_07424412.1| two component system sensor kinase [Mycobacterium tuberculosis 
SUMu003]
 gi|306790457|ref|ZP_07428779.1| two component system sensor kinase [Mycobacterium tuberculosis 
SUMu004]
 13 more sequence titles
 Length=500

 Score =  988 bits (2553),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 500/501 (99%), Positives = 500/501 (99%), Gaps = 1/501 (0%)

Query  1    MSTLGDLLAEHTVLPGSAVDHLHAVVGEWQLLADLSFADYLMWVRRDDGVLVCVAQCRPN  60
            MSTLGDLLAEHTVLPGSAVDHLHAVVGEWQLLADLSFADYLMWVRRDDGVLVCVAQCRPN
Sbjct  1    MSTLGDLLAEHTVLPGSAVDHLHAVVGEWQLLADLSFADYLMWVRRDDGVLVCVAQCRPN  60

Query  61   TGPTVVHTDAVGTVVAANSMPLVAATFSGGVPGREGAVGQQNSCQHDGHSVEVSPVRFGD  120
            TGPTVVHTDAVGTVVAANSMPLVAATFSGGVPGREGAVGQQNSCQHDGHSVEVSPVRFGD
Sbjct  61   TGPTVVHTDAVGTVVAANSMPLVAATFSGGVPGREGAVGQQNSCQHDGHSVEVSPVRFGD  120

Query  121  QVVAVLTRHQPELAARRRSGHLETAYRLCATDLLRMLAEGTFPDAGDVAMSRSSPRAGDG  180
            QVVAVLTRHQPELAARRRSGHLETAYRLCATDLLRMLAEGTFPDAGDVAMSRSSPRAGDG
Sbjct  121  QVVAVLTRHQPELAARRRSGHLETAYRLCATDLLRMLAEGTFPDAGDVAMSRSSPRAGDG  180

Query  181  FIRLDVDGVVSYASPNALSAYHRMGLTTELEGVNLIDATRPLISDPFEAHEVDEHVQDLL  240
            FIRLDVDGVVSYASPNALSAYHRMGLTTELEGVNLIDATRPLISDPFEAHEVDEHVQDLL
Sbjct  181  FIRLDVDGVVSYASPNALSAYHRMGLTTELEGVNLIDATRPLISDPFEAHEVDEHVQDLL  240

Query  241  AGDGKGMRMEVDAGGATVLLRTLPLVVAGRNVGAAILIRDVTEVKRRDRALISKDATIRE  300
            AGDGKGMRMEVDAGGATVLLRTLPLVVAGRNVGAAILIRDVTEVKRRDRALISKDATIRE
Sbjct  241  AGDGKGMRMEVDAGGATVLLRTLPLVVAGRNVGAAILIRDVTEVKRRDRALISKDATIRE  300

Query  301  IHHRVKNNLQTVAALLRLQARRTSNAEGREALIESVRRVSSIALVHDALSMSVDEQVNLD  360
            IHHRVKNNLQTVAALLRLQARRTSNAEGREALIESVRRVSSIALVHDALSMSVDEQVNLD
Sbjct  301  IHHRVKNNLQTVAALLRLQARRTSNAEGREALIESVRRVSSIALVHDALSMSVDEQVNLD  360

Query  361  EVIDRILPIMNDVASVDRPIRINRVGDLGVLDSDRATALIMVITELVQNAIEHAFDPAAA  420
            EVIDRILPIMNDVASVDRPIRINRVGDLGVLDSDRATALIMVITELVQNAIEHAFDP AA
Sbjct  361  EVIDRILPIMNDVASVDRPIRINRVGDLGVLDSDRATALIMVITELVQNAIEHAFDP-AA  419

Query  421  EGSVTIRAERSARWLDVVVHDDGLGLPQGFSLEKSDSLGLQIVRTLVSAELDGSLGMRDA  480
            EGSVTIRAERSARWLDVVVHDDGLGLPQGFSLEKSDSLGLQIVRTLVSAELDGSLGMRDA
Sbjct  420  EGSVTIRAERSARWLDVVVHDDGLGLPQGFSLEKSDSLGLQIVRTLVSAELDGSLGMRDA  479

Query  481  RERGTDVVLRVPVGRRGRLML  501
            RERGTDVVLRVPVGRRGRLML
Sbjct  480  RERGTDVVLRVPVGRRGRLML  500


>gi|289751910|ref|ZP_06511288.1| signal transduction histidine kinase [Mycobacterium tuberculosis 
T92]
 gi|289692497|gb|EFD59926.1| signal transduction histidine kinase [Mycobacterium tuberculosis 
T92]
Length=475

 Score =  915 bits (2365),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 459/459 (100%), Positives = 459/459 (100%), Gaps = 0/459 (0%)

Query  1    MSTLGDLLAEHTVLPGSAVDHLHAVVGEWQLLADLSFADYLMWVRRDDGVLVCVAQCRPN  60
            MSTLGDLLAEHTVLPGSAVDHLHAVVGEWQLLADLSFADYLMWVRRDDGVLVCVAQCRPN
Sbjct  1    MSTLGDLLAEHTVLPGSAVDHLHAVVGEWQLLADLSFADYLMWVRRDDGVLVCVAQCRPN  60

Query  61   TGPTVVHTDAVGTVVAANSMPLVAATFSGGVPGREGAVGQQNSCQHDGHSVEVSPVRFGD  120
            TGPTVVHTDAVGTVVAANSMPLVAATFSGGVPGREGAVGQQNSCQHDGHSVEVSPVRFGD
Sbjct  61   TGPTVVHTDAVGTVVAANSMPLVAATFSGGVPGREGAVGQQNSCQHDGHSVEVSPVRFGD  120

Query  121  QVVAVLTRHQPELAARRRSGHLETAYRLCATDLLRMLAEGTFPDAGDVAMSRSSPRAGDG  180
            QVVAVLTRHQPELAARRRSGHLETAYRLCATDLLRMLAEGTFPDAGDVAMSRSSPRAGDG
Sbjct  121  QVVAVLTRHQPELAARRRSGHLETAYRLCATDLLRMLAEGTFPDAGDVAMSRSSPRAGDG  180

Query  181  FIRLDVDGVVSYASPNALSAYHRMGLTTELEGVNLIDATRPLISDPFEAHEVDEHVQDLL  240
            FIRLDVDGVVSYASPNALSAYHRMGLTTELEGVNLIDATRPLISDPFEAHEVDEHVQDLL
Sbjct  181  FIRLDVDGVVSYASPNALSAYHRMGLTTELEGVNLIDATRPLISDPFEAHEVDEHVQDLL  240

Query  241  AGDGKGMRMEVDAGGATVLLRTLPLVVAGRNVGAAILIRDVTEVKRRDRALISKDATIRE  300
            AGDGKGMRMEVDAGGATVLLRTLPLVVAGRNVGAAILIRDVTEVKRRDRALISKDATIRE
Sbjct  241  AGDGKGMRMEVDAGGATVLLRTLPLVVAGRNVGAAILIRDVTEVKRRDRALISKDATIRE  300

Query  301  IHHRVKNNLQTVAALLRLQARRTSNAEGREALIESVRRVSSIALVHDALSMSVDEQVNLD  360
            IHHRVKNNLQTVAALLRLQARRTSNAEGREALIESVRRVSSIALVHDALSMSVDEQVNLD
Sbjct  301  IHHRVKNNLQTVAALLRLQARRTSNAEGREALIESVRRVSSIALVHDALSMSVDEQVNLD  360

Query  361  EVIDRILPIMNDVASVDRPIRINRVGDLGVLDSDRATALIMVITELVQNAIEHAFDPAAA  420
            EVIDRILPIMNDVASVDRPIRINRVGDLGVLDSDRATALIMVITELVQNAIEHAFDPAAA
Sbjct  361  EVIDRILPIMNDVASVDRPIRINRVGDLGVLDSDRATALIMVITELVQNAIEHAFDPAAA  420

Query  421  EGSVTIRAERSARWLDVVVHDDGLGLPQGFSLEKSDSLG  459
            EGSVTIRAERSARWLDVVVHDDGLGLPQGFSLEKSDSLG
Sbjct  421  EGSVTIRAERSARWLDVVVHDDGLGLPQGFSLEKSDSLG  459


>gi|240170390|ref|ZP_04749049.1| sensor kinase from two-component regulatory system [Mycobacterium 
kansasii ATCC 12478]
Length=500

 Score =  834 bits (2154),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 427/501 (86%), Positives = 457/501 (92%), Gaps = 2/501 (0%)

Query  1    MSTLGDLLAEHTVLPGSAVDHLHAVVGEWQLLADLSFADYLMWVRRDDGVLVCVAQCRPN  60
            MSTLGDLLAEHTVLPG+AVDHLHAVVGEWQLLADLSFADYLMWVRRDDGVLVCVAQCRPN
Sbjct  1    MSTLGDLLAEHTVLPGNAVDHLHAVVGEWQLLADLSFADYLMWVRRDDGVLVCVAQCRPN  60

Query  61   TGPTVVHTDAVGTVVAANSMPLVAATFSGGVPGREGAVGQQNSCQHDGHSVEVSPVRFGD  120
            T PTV+ TDAVGT VA + +PLVA TF+ G    +G   + +S +  G +V  SPVR+G 
Sbjct  61   TAPTVLQTDAVGTAVAGDKLPLVAETFTSGAAKWQGD-AECHSGELPGPNVAASPVRYGG  119

Query  121  QVVAVLTRHQPELAARRRSGHLETAYRLCATDLLRMLAEGTFPDAGDVAMSRSSPRAGDG  180
            QVVAVLT+HQ  +AA+R SGHLETAYR CA DLL ML+EGTFPD GDVAMSRS+PRAGDG
Sbjct  120  QVVAVLTQHQTAVAAQRASGHLETAYRECAIDLLHMLSEGTFPDVGDVAMSRSTPRAGDG  179

Query  181  FIRLDVDGVVSYASPNALSAYHRMGLTTELEGVNLIDATRPLISDPFEAHEVDEHVQDLL  240
            FIRL+VDGVV+YASPNALSAYHRMGLTTELEG +L++ TRPLISDPFEA EV EHV+DLL
Sbjct  180  FIRLNVDGVVAYASPNALSAYHRMGLTTELEGHHLVEVTRPLISDPFEAEEVAEHVRDLL  239

Query  241  AGDGKGMRMEVDAGGATVLLRTLPLVVAGRNVGAAILIRDVTEVKRRDRALISKDATIRE  300
             G G  MRMEVDAGGATVLLRTLPL+V G + GAAILIRDVTEVKRRDRALISKDATIRE
Sbjct  240  TG-GPSMRMEVDAGGATVLLRTLPLMVHGASAGAAILIRDVTEVKRRDRALISKDATIRE  298

Query  301  IHHRVKNNLQTVAALLRLQARRTSNAEGREALIESVRRVSSIALVHDALSMSVDEQVNLD  360
            IHHRVKNNLQTVAALLRLQARRT+NAEGREALIESVRRVSSIALVHDALSMSVDEQVNLD
Sbjct  299  IHHRVKNNLQTVAALLRLQARRTANAEGREALIESVRRVSSIALVHDALSMSVDEQVNLD  358

Query  361  EVIDRILPIMNDVASVDRPIRINRVGDLGVLDSDRATALIMVITELVQNAIEHAFDPAAA  420
            EVIDRILPIMNDVASVDRPIRINRVGDLGVLDSDRATALIMVITELVQNAIEHAFDPAA 
Sbjct  359  EVIDRILPIMNDVASVDRPIRINRVGDLGVLDSDRATALIMVITELVQNAIEHAFDPAAQ  418

Query  421  EGSVTIRAERSARWLDVVVHDDGLGLPQGFSLEKSDSLGLQIVRTLVSAELDGSLGMRDA  480
             GSVTIRAERSARWLDVVVHDDG GLP+GF+LEKSDSLGLQIVRTLVSAELDGSLGMR+A
Sbjct  419  GGSVTIRAERSARWLDVVVHDDGRGLPEGFNLEKSDSLGLQIVRTLVSAELDGSLGMREA  478

Query  481  RERGTDVVLRVPVGRRGRLML  501
             ERGTDVVLRVP+GRRGRLM+
Sbjct  479  PERGTDVVLRVPIGRRGRLMV  499


>gi|183981360|ref|YP_001849651.1| sensor kinase from two-component regulatory system [Mycobacterium 
marinum M]
 gi|183174686|gb|ACC39796.1| sensor kinase from two-component regulatory system [Mycobacterium 
marinum M]
Length=499

 Score =  832 bits (2150),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 427/500 (86%), Positives = 455/500 (91%), Gaps = 2/500 (0%)

Query  1    MSTLGDLLAEHTVLPGSAVDHLHAVVGEWQLLADLSFADYLMWVRRDDGVLVCVAQCRPN  60
            MSTLG+LLAE+T+LPG+AVDHLHAVVGEWQLLADLSFADYLMWV RDDG LVCVAQCRPN
Sbjct  1    MSTLGNLLAENTMLPGNAVDHLHAVVGEWQLLADLSFADYLMWVARDDGALVCVAQCRPN  60

Query  61   TGPTVVHTDAVGTVVAANSMPLVAATFSGGVPGREGAVGQQNSCQHDGHSVEVSPVRFGD  120
            T PTV+ TDAVG+VV A+ +PLVA TF+ G   R+    QQ+  Q  G S+E SPVR+GD
Sbjct  61   TAPTVLQTDAVGSVVEADRLPLVAETFASGSARRDSDADQQHLGQLPGPSIEASPVRYGD  120

Query  121  QVVAVLTRHQPELAARRRSGHLETAYRLCATDLLRMLAEGTFPDAGDVAMSRSSPRAGDG  180
            QVVAVLT+HQ  +AA R SGHLE+AYR CATDLL+MLAEGTFPD GDVAMSRS+PRAGDG
Sbjct  121  QVVAVLTQHQTAVAAERASGHLESAYRDCATDLLQMLAEGTFPDVGDVAMSRSTPRAGDG  180

Query  181  FIRLDVDGVVSYASPNALSAYHRMGLTTELEGVNLIDATRPLISDPFEAHEVDEHVQDLL  240
            FIRLDVDGV  YASPNALSAYHRMGLTTELEG  LI+ TRPLISDPFEA EV EHV+DLL
Sbjct  181  FIRLDVDGVAIYASPNALSAYHRMGLTTELEGHELIEVTRPLISDPFEAEEVAEHVRDLL  240

Query  241  AGDGKGMRMEVDAGGATVLLRTLPLVVAGRNVGAAILIRDVTEVKRRDRALISKDATIRE  300
             G G+ MRMEVDAGGATVLLRTLPLVV G + GAAILIRDVTEVKRRDRALISKDATIRE
Sbjct  241  VG-GRSMRMEVDAGGATVLLRTLPLVVGGVSAGAAILIRDVTEVKRRDRALISKDATIRE  299

Query  301  IHHRVKNNLQTVAALLRLQARRTSNAEGREALIESVRRVSSIALVHDALSMSVDEQVNLD  360
            IHHRVKNNLQTVAALLRLQARRT+NAEGREALIESVRRVSSIALVHDALSMSVDEQVNLD
Sbjct  300  IHHRVKNNLQTVAALLRLQARRTTNAEGREALIESVRRVSSIALVHDALSMSVDEQVNLD  359

Query  361  EVIDRILPIMNDVASVDRPIRINRVGDLGVLDSDRATALIMVITELVQNAIEHAFDPAAA  420
            EVIDRILPIMNDVASVDRPIRINRVGDLGVLDSDRATALIMVITELVQNAIEHAFDP AA
Sbjct  360  EVIDRILPIMNDVASVDRPIRINRVGDLGVLDSDRATALIMVITELVQNAIEHAFDP-AA  418

Query  421  EGSVTIRAERSARWLDVVVHDDGLGLPQGFSLEKSDSLGLQIVRTLVSAELDGSLGMRDA  480
            +G+VTIRAERSARWLDVVVHDDG GLP GFSLEKSDSLGLQIVRTLVSAELDGSLGMR+A
Sbjct  419  QGAVTIRAERSARWLDVVVHDDGRGLPSGFSLEKSDSLGLQIVRTLVSAELDGSLGMREA  478

Query  481  RERGTDVVLRVPVGRRGRLM  500
              RGTDVVLRVP+GRRGRL+
Sbjct  479  PGRGTDVVLRVPIGRRGRLL  498


>gi|118618024|ref|YP_906356.1| sensor kinase from two component regulatory system [Mycobacterium 
ulcerans Agy99]
 gi|118570134|gb|ABL04885.1| sensor kinase from two component regulatory system [Mycobacterium 
ulcerans Agy99]
Length=499

 Score =  831 bits (2146),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 426/500 (86%), Positives = 454/500 (91%), Gaps = 2/500 (0%)

Query  1    MSTLGDLLAEHTVLPGSAVDHLHAVVGEWQLLADLSFADYLMWVRRDDGVLVCVAQCRPN  60
            MSTLG+LLAE+T+LPG+AVDHLHAVVGEWQLLADLSFADYLMWV RDDG LVCVAQCRPN
Sbjct  1    MSTLGNLLAENTMLPGNAVDHLHAVVGEWQLLADLSFADYLMWVARDDGALVCVAQCRPN  60

Query  61   TGPTVVHTDAVGTVVAANSMPLVAATFSGGVPGREGAVGQQNSCQHDGHSVEVSPVRFGD  120
            T PTV+ TDAVG+VV A+ +PLVA TF+ G   R+    QQ+  Q  G S+E SPVR+GD
Sbjct  61   TAPTVLQTDAVGSVVEADRLPLVAETFASGSARRDSDADQQHLGQLPGPSIEASPVRYGD  120

Query  121  QVVAVLTRHQPELAARRRSGHLETAYRLCATDLLRMLAEGTFPDAGDVAMSRSSPRAGDG  180
            QVVAVLT+HQ  +AA R SGHLE+AYR CATDLL+MLAEGTFPD GDVAMSRS+PRAGDG
Sbjct  121  QVVAVLTQHQTAVAAERASGHLESAYRDCATDLLQMLAEGTFPDVGDVAMSRSTPRAGDG  180

Query  181  FIRLDVDGVVSYASPNALSAYHRMGLTTELEGVNLIDATRPLISDPFEAHEVDEHVQDLL  240
            FIRLDVDGV  YASPNALSAYHRMGLTTELEG  LI+ TRPLISDPFEA EV EHV+DLL
Sbjct  181  FIRLDVDGVAIYASPNALSAYHRMGLTTELEGHELIEVTRPLISDPFEAEEVAEHVRDLL  240

Query  241  AGDGKGMRMEVDAGGATVLLRTLPLVVAGRNVGAAILIRDVTEVKRRDRALISKDATIRE  300
             G G+ MRMEVDAGGATVLLRTLPLVV G + GAAILIRDVTEVKRRDRALISKDATIRE
Sbjct  241  VG-GRSMRMEVDAGGATVLLRTLPLVVGGVSAGAAILIRDVTEVKRRDRALISKDATIRE  299

Query  301  IHHRVKNNLQTVAALLRLQARRTSNAEGREALIESVRRVSSIALVHDALSMSVDEQVNLD  360
            IHHRVKNNLQTVAALLRLQARRT+NAEGREAL ESVRRVSSIALVHDALSMSVDEQVNLD
Sbjct  300  IHHRVKNNLQTVAALLRLQARRTTNAEGREALTESVRRVSSIALVHDALSMSVDEQVNLD  359

Query  361  EVIDRILPIMNDVASVDRPIRINRVGDLGVLDSDRATALIMVITELVQNAIEHAFDPAAA  420
            EVIDRILPIMNDVASVDRPIRINRVGDLGVLDSDRATALIMVITELVQNAIEHAFDP AA
Sbjct  360  EVIDRILPIMNDVASVDRPIRINRVGDLGVLDSDRATALIMVITELVQNAIEHAFDP-AA  418

Query  421  EGSVTIRAERSARWLDVVVHDDGLGLPQGFSLEKSDSLGLQIVRTLVSAELDGSLGMRDA  480
            +G+VTIRAERSARWLDVVVHDDG GLP GFSLEKSDSLGLQIVRTLVSAELDGSLGMR+A
Sbjct  419  QGAVTIRAERSARWLDVVVHDDGRGLPSGFSLEKSDSLGLQIVRTLVSAELDGSLGMREA  478

Query  481  RERGTDVVLRVPVGRRGRLM  500
              RGTDVVLRVP+GRRGRL+
Sbjct  479  PGRGTDVVLRVPIGRRGRLL  498


>gi|254776607|ref|ZP_05218123.1| sensor histidine kinase [Mycobacterium avium subsp. avium ATCC 
25291]
Length=499

 Score =  827 bits (2135),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 423/501 (85%), Positives = 451/501 (91%), Gaps = 2/501 (0%)

Query  1    MSTLGDLLAEHTVLPGSAVDHLHAVVGEWQLLADLSFADYLMWVRRDDGVLVCVAQCRPN  60
            MSTLGDLLAEHT+LPG+AVDHLHAVVGEWQLLADLSFADYLMWV RDDG+LVCVAQCRPN
Sbjct  1    MSTLGDLLAEHTMLPGNAVDHLHAVVGEWQLLADLSFADYLMWVCRDDGMLVCVAQCRPN  60

Query  61   TGPTVVHTDAVGTVVAANSMPLVAATFSGGVPGREGAVGQQNSCQHDGHSVEVSPVRFGD  120
            T PTV+ TDAVGTVVA+  + LVA TF+ G    +    QQ+S     H VE SPVR+G 
Sbjct  61   TAPTVLQTDAVGTVVASERLTLVAETFASGAAKADDVAAQQDSWLPGTH-VEASPVRYGG  119

Query  121  QVVAVLTRHQPELAARRRSGHLETAYRLCATDLLRMLAEGTFPDAGDVAMSRSSPRAGDG  180
            +VVAVLTRHQ  +AA R SG LE AYR CA DL+ MLAEGTFPD GDVAMSRS+PRAGDG
Sbjct  120  RVVAVLTRHQTAVAADRASGQLEIAYRECAADLVHMLAEGTFPDVGDVAMSRSTPRAGDG  179

Query  181  FIRLDVDGVVSYASPNALSAYHRMGLTTELEGVNLIDATRPLISDPFEAHEVDEHVQDLL  240
            FIRLDV+GVV+YASPNALSAYHRMGLTTELEG NLI+ TRPLISD FEA E+ EHV+DLL
Sbjct  180  FIRLDVNGVVAYASPNALSAYHRMGLTTELEGHNLIEITRPLISDSFEAQEMAEHVKDLL  239

Query  241  AGDGKGMRMEVDAGGATVLLRTLPLVVAGRNVGAAILIRDVTEVKRRDRALISKDATIRE  300
            AG GK MRMEVDAGGATVLLRTLPLVV G + GAA+LIRDVTEVKRRDRALISKDATIRE
Sbjct  240  AG-GKSMRMEVDAGGATVLLRTLPLVVNGASAGAAVLIRDVTEVKRRDRALISKDATIRE  298

Query  301  IHHRVKNNLQTVAALLRLQARRTSNAEGREALIESVRRVSSIALVHDALSMSVDEQVNLD  360
            IHHRVKNNLQTVAALLRLQARRT+N EGREALIESVRRVSSIALVHDALSMSVDEQVNLD
Sbjct  299  IHHRVKNNLQTVAALLRLQARRTTNPEGREALIESVRRVSSIALVHDALSMSVDEQVNLD  358

Query  361  EVIDRILPIMNDVASVDRPIRINRVGDLGVLDSDRATALIMVITELVQNAIEHAFDPAAA  420
            EVIDRILPIMNDVASVDRPIRINRVGDLGVLDSDRATALIMVITELVQNAIEHAFDPAAA
Sbjct  359  EVIDRILPIMNDVASVDRPIRINRVGDLGVLDSDRATALIMVITELVQNAIEHAFDPAAA  418

Query  421  EGSVTIRAERSARWLDVVVHDDGLGLPQGFSLEKSDSLGLQIVRTLVSAELDGSLGMRDA  480
            EGSVTIRAERSARWLDVVVHDDG GLP+GFSLE SDSLGLQIVRTLVSAELDG+LGM +A
Sbjct  419  EGSVTIRAERSARWLDVVVHDDGRGLPEGFSLEASDSLGLQIVRTLVSAELDGTLGMSEA  478

Query  481  RERGTDVVLRVPVGRRGRLML  501
             ERGTDVVLRVP+GRR R++L
Sbjct  479  SERGTDVVLRVPIGRRTRMLL  499


>gi|118466753|ref|YP_883315.1| sensor histidine kinase [Mycobacterium avium 104]
 gi|118168040|gb|ABK68937.1| sensor histidine kinase [Mycobacterium avium 104]
Length=499

 Score =  826 bits (2134),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 423/501 (85%), Positives = 450/501 (90%), Gaps = 2/501 (0%)

Query  1    MSTLGDLLAEHTVLPGSAVDHLHAVVGEWQLLADLSFADYLMWVRRDDGVLVCVAQCRPN  60
            MSTLGDLLAEHT+LPG+AVDHLHAVVGEWQLLADLSFADYLMWV RDDG+LVCVAQCRPN
Sbjct  1    MSTLGDLLAEHTMLPGNAVDHLHAVVGEWQLLADLSFADYLMWVCRDDGMLVCVAQCRPN  60

Query  61   TGPTVVHTDAVGTVVAANSMPLVAATFSGGVPGREGAVGQQNSCQHDGHSVEVSPVRFGD  120
            T PTV+ TDAVGTVVA+  + LVA TF+ G    +    QQ+S     H VE SPVR+G 
Sbjct  61   TAPTVLQTDAVGTVVASERLTLVAETFASGAAKADDVAAQQDSWLPGTH-VEASPVRYGG  119

Query  121  QVVAVLTRHQPELAARRRSGHLETAYRLCATDLLRMLAEGTFPDAGDVAMSRSSPRAGDG  180
             VVAVLTRHQ  +AA R SG LE AYR CA DL+ MLAEGTFPD GDVAMSRS+PRAGDG
Sbjct  120  HVVAVLTRHQTAVAADRASGQLEIAYRECAADLVHMLAEGTFPDVGDVAMSRSTPRAGDG  179

Query  181  FIRLDVDGVVSYASPNALSAYHRMGLTTELEGVNLIDATRPLISDPFEAHEVDEHVQDLL  240
            FIRLDV+GVV+YASPNALSAYHRMGLTTELEG NLI+ TRPLISD FEA E+ EHV+DLL
Sbjct  180  FIRLDVNGVVAYASPNALSAYHRMGLTTELEGHNLIEITRPLISDSFEAQEMAEHVKDLL  239

Query  241  AGDGKGMRMEVDAGGATVLLRTLPLVVAGRNVGAAILIRDVTEVKRRDRALISKDATIRE  300
            AG GK MRMEVDAGGATVLLRTLPLVV G + GAA+LIRDVTEVKRRDRALISKDATIRE
Sbjct  240  AG-GKSMRMEVDAGGATVLLRTLPLVVNGASAGAAVLIRDVTEVKRRDRALISKDATIRE  298

Query  301  IHHRVKNNLQTVAALLRLQARRTSNAEGREALIESVRRVSSIALVHDALSMSVDEQVNLD  360
            IHHRVKNNLQTVAALLRLQARRT+N EGREALIESVRRVSSIALVHDALSMSVDEQVNLD
Sbjct  299  IHHRVKNNLQTVAALLRLQARRTTNPEGREALIESVRRVSSIALVHDALSMSVDEQVNLD  358

Query  361  EVIDRILPIMNDVASVDRPIRINRVGDLGVLDSDRATALIMVITELVQNAIEHAFDPAAA  420
            EVIDRILPIMNDVASVDRPIRINRVGDLGVLDSDRATALIMVITELVQNAIEHAFDPAAA
Sbjct  359  EVIDRILPIMNDVASVDRPIRINRVGDLGVLDSDRATALIMVITELVQNAIEHAFDPAAA  418

Query  421  EGSVTIRAERSARWLDVVVHDDGLGLPQGFSLEKSDSLGLQIVRTLVSAELDGSLGMRDA  480
            EGSVTIRAERSARWLDVVVHDDG GLP+GFSLE SDSLGLQIVRTLVSAELDG+LGM +A
Sbjct  419  EGSVTIRAERSARWLDVVVHDDGRGLPEGFSLEASDSLGLQIVRTLVSAELDGTLGMSEA  478

Query  481  RERGTDVVLRVPVGRRGRLML  501
             ERGTDVVLRVP+GRR R++L
Sbjct  479  SERGTDVVLRVPIGRRTRMLL  499


>gi|41409419|ref|NP_962255.1| hypothetical protein MAP3321c [Mycobacterium avium subsp. paratuberculosis 
K-10]
 gi|41398250|gb|AAS05871.1| hypothetical protein MAP_3321c [Mycobacterium avium subsp. paratuberculosis 
K-10]
 gi|336459511|gb|EGO38448.1| signal transduction histidine kinase [Mycobacterium avium subsp. 
paratuberculosis S397]
Length=499

 Score =  825 bits (2131),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 422/501 (85%), Positives = 449/501 (90%), Gaps = 2/501 (0%)

Query  1    MSTLGDLLAEHTVLPGSAVDHLHAVVGEWQLLADLSFADYLMWVRRDDGVLVCVAQCRPN  60
            MSTLGDLLAEHT+LPG+AVDHLHAVVGEWQLLADLSFADYLMWV RDDG+LVCVAQCRPN
Sbjct  1    MSTLGDLLAEHTMLPGNAVDHLHAVVGEWQLLADLSFADYLMWVCRDDGMLVCVAQCRPN  60

Query  61   TGPTVVHTDAVGTVVAANSMPLVAATFSGGVPGREGAVGQQNSCQHDGHSVEVSPVRFGD  120
            T PTV+ TDAVGTVVA+  + LVA TF+ G    +    QQ+S     H VE SPVR+G 
Sbjct  61   TAPTVLQTDAVGTVVASERLTLVAETFASGAAKADDVAAQQDSWLPGTH-VEASPVRYGG  119

Query  121  QVVAVLTRHQPELAARRRSGHLETAYRLCATDLLRMLAEGTFPDAGDVAMSRSSPRAGDG  180
             VVAVLTRHQ  +AA R SG LE AYR CA DL+ MLAEGTFPD GDVAMSRS+PRAGDG
Sbjct  120  HVVAVLTRHQTAVAADRASGQLEIAYRECAADLVHMLAEGTFPDVGDVAMSRSTPRAGDG  179

Query  181  FIRLDVDGVVSYASPNALSAYHRMGLTTELEGVNLIDATRPLISDPFEAHEVDEHVQDLL  240
            FIRLDV+GVV+YASPNALSAYHRMGLTTELEG NLI+ TRPLISD FEA E+ EHV+DLL
Sbjct  180  FIRLDVNGVVAYASPNALSAYHRMGLTTELEGHNLIEITRPLISDSFEAQEMAEHVKDLL  239

Query  241  AGDGKGMRMEVDAGGATVLLRTLPLVVAGRNVGAAILIRDVTEVKRRDRALISKDATIRE  300
            AG GK MRMEVDAGGATVLLRTLPLVV G + GAA+LIRDVTEVKRRDRALISKDATIRE
Sbjct  240  AG-GKSMRMEVDAGGATVLLRTLPLVVNGASAGAAVLIRDVTEVKRRDRALISKDATIRE  298

Query  301  IHHRVKNNLQTVAALLRLQARRTSNAEGREALIESVRRVSSIALVHDALSMSVDEQVNLD  360
            IHHRVKNNLQTVAALLRLQARRT+N EGREALIESVRRVSSIALVHDALSMSVDEQVNLD
Sbjct  299  IHHRVKNNLQTVAALLRLQARRTTNPEGREALIESVRRVSSIALVHDALSMSVDEQVNLD  358

Query  361  EVIDRILPIMNDVASVDRPIRINRVGDLGVLDSDRATALIMVITELVQNAIEHAFDPAAA  420
            EVIDRILPIMNDVASVDRPIRINRVGDLGVLDSDRATALIMVITELVQNAIEHAFDP AA
Sbjct  359  EVIDRILPIMNDVASVDRPIRINRVGDLGVLDSDRATALIMVITELVQNAIEHAFDPTAA  418

Query  421  EGSVTIRAERSARWLDVVVHDDGLGLPQGFSLEKSDSLGLQIVRTLVSAELDGSLGMRDA  480
            EGSVTIRAERSARWLDVVVHDDG GLP+GFSLE SDSLGLQIVRTLVSAELDG+LGM +A
Sbjct  419  EGSVTIRAERSARWLDVVVHDDGRGLPEGFSLEASDSLGLQIVRTLVSAELDGTLGMSEA  478

Query  481  RERGTDVVLRVPVGRRGRLML  501
             ERGTDVVLRVP+GRR R++L
Sbjct  479  SERGTDVVLRVPIGRRTRMLL  499


>gi|342861178|ref|ZP_08717827.1| sensor histidine kinase [Mycobacterium colombiense CECT 3035]
 gi|342131622|gb|EGT84892.1| sensor histidine kinase [Mycobacterium colombiense CECT 3035]
Length=499

 Score =  821 bits (2121),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 423/501 (85%), Positives = 446/501 (90%), Gaps = 2/501 (0%)

Query  1    MSTLGDLLAEHTVLPGSAVDHLHAVVGEWQLLADLSFADYLMWVRRDDGVLVCVAQCRPN  60
            MSTLGDLLAEHT+LPG+AVDHLHAVVGEWQLLADLSFADYLMWVRRDDGVLVCVAQCRPN
Sbjct  1    MSTLGDLLAEHTMLPGNAVDHLHAVVGEWQLLADLSFADYLMWVRRDDGVLVCVAQCRPN  60

Query  61   TGPTVVHTDAVGTVVAANSMPLVAATFSGGVPGREGAVGQQNSCQHDGHSVEVSPVRFGD  120
            T PT + TDAVGT V ++ + LVA TF  G   R    G ++S     H VE SPVR+G 
Sbjct  61   TAPTALQTDAVGTAVGSDRLQLVAETFESGTAKRNDVAGPEDSWLPGTH-VEASPVRYGG  119

Query  121  QVVAVLTRHQPELAARRRSGHLETAYRLCATDLLRMLAEGTFPDAGDVAMSRSSPRAGDG  180
             VVAVLT HQ  LAA R SG LE AYR CATDL++MLAEGTFPD GDV MSRS+PRAGDG
Sbjct  120  TVVAVLTHHQTALAADRASGQLEIAYRECATDLVQMLAEGTFPDVGDVVMSRSTPRAGDG  179

Query  181  FIRLDVDGVVSYASPNALSAYHRMGLTTELEGVNLIDATRPLISDPFEAHEVDEHVQDLL  240
            FIRLDV GVV+YASPNALSAYHRMGLTTELEG NLID TRPLISDPFEA EV EHV+DL+
Sbjct  180  FIRLDVHGVVAYASPNALSAYHRMGLTTELEGHNLIDVTRPLISDPFEAQEVAEHVRDLV  239

Query  241  AGDGKGMRMEVDAGGATVLLRTLPLVVAGRNVGAAILIRDVTEVKRRDRALISKDATIRE  300
            AG G+ MRMEVDAGGATVLLRTLPL+V G + GAA+LIRDVTEVKRRDRALISKDATIRE
Sbjct  240  AG-GRSMRMEVDAGGATVLLRTLPLMVDGVSAGAAVLIRDVTEVKRRDRALISKDATIRE  298

Query  301  IHHRVKNNLQTVAALLRLQARRTSNAEGREALIESVRRVSSIALVHDALSMSVDEQVNLD  360
            IHHRVKNNLQTVAALLRLQARRT+NAEGREALIESVRRVSSIALVHDALSMSVDEQVNLD
Sbjct  299  IHHRVKNNLQTVAALLRLQARRTANAEGREALIESVRRVSSIALVHDALSMSVDEQVNLD  358

Query  361  EVIDRILPIMNDVASVDRPIRINRVGDLGVLDSDRATALIMVITELVQNAIEHAFDPAAA  420
            EVIDRILPIMNDVASVDRPIRINRVGDLGVLDSDRATALIMVITELVQNAIEHAFDPAAA
Sbjct  359  EVIDRILPIMNDVASVDRPIRINRVGDLGVLDSDRATALIMVITELVQNAIEHAFDPAAA  418

Query  421  EGSVTIRAERSARWLDVVVHDDGLGLPQGFSLEKSDSLGLQIVRTLVSAELDGSLGMRDA  480
            EGSVTIRAERSARWLDVVVHDDG GLP GFSLE SDSLGLQIVRTLVSAELDG+LGMR A
Sbjct  419  EGSVTIRAERSARWLDVVVHDDGRGLPAGFSLETSDSLGLQIVRTLVSAELDGTLGMRQA  478

Query  481  RERGTDVVLRVPVGRRGRLML  501
               GTDVVLRVP+GRR RL+L
Sbjct  479  PVTGTDVVLRVPIGRRTRLLL  499


>gi|296169003|ref|ZP_06850669.1| sensor histidine kinase [Mycobacterium parascrofulaceum ATCC 
BAA-614]
 gi|295896345|gb|EFG76001.1| sensor histidine kinase [Mycobacterium parascrofulaceum ATCC 
BAA-614]
Length=500

 Score =  818 bits (2114),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 423/501 (85%), Positives = 448/501 (90%), Gaps = 2/501 (0%)

Query  1    MSTLGDLLAEHTVLPGSAVDHLHAVVGEWQLLADLSFADYLMWVRRDDGVLVCVAQCRPN  60
            MSTLGDLLAEHTVLPG+AVDHLHAVVGEWQLLADLSFADYLMWVRRDDG LVCVAQCRPN
Sbjct  2    MSTLGDLLAEHTVLPGNAVDHLHAVVGEWQLLADLSFADYLMWVRRDDGKLVCVAQCRPN  61

Query  61   TGPTVVHTDAVGTVVAANSMPLVAATFSGGVPGREGAVGQQNSCQHDGHSVEVSPVRFGD  120
            T PTV+ TD+VG+VV A  + LVA TF  G P R+G  GQQ+S     H VE SPVR+G 
Sbjct  62   TAPTVLVTDSVGSVVDAERLALVADTFDSGAPQRDGVGGQQDSWLPGPH-VEASPVRYGG  120

Query  121  QVVAVLTRHQPELAARRRSGHLETAYRLCATDLLRMLAEGTFPDAGDVAMSRSSPRAGDG  180
            QVVAVLTRHQ   AA R SG LETAYR CA DL+ MLA+GTFPD GDV MSRS+PRAGDG
Sbjct  121  QVVAVLTRHQTAGAADRTSGQLETAYRDCAGDLVHMLADGTFPDVGDVVMSRSTPRAGDG  180

Query  181  FIRLDVDGVVSYASPNALSAYHRMGLTTELEGVNLIDATRPLISDPFEAHEVDEHVQDLL  240
            FIRLDV+GVV+YASPNA+SAYHRMGLT+ELEG NL+  TRPLISDPFEA E+ EHV DLL
Sbjct  181  FIRLDVNGVVAYASPNAVSAYHRMGLTSELEGRNLVKVTRPLISDPFEAQELAEHVLDLL  240

Query  241  AGDGKGMRMEVDAGGATVLLRTLPLVVAGRNVGAAILIRDVTEVKRRDRALISKDATIRE  300
            AG G+ MRMEVDAGGATVLLRTLPL+V G + GAA+LIRDVTEVKRRDRALISKDATIRE
Sbjct  241  AG-GRSMRMEVDAGGATVLLRTLPLMVDGASAGAAVLIRDVTEVKRRDRALISKDATIRE  299

Query  301  IHHRVKNNLQTVAALLRLQARRTSNAEGREALIESVRRVSSIALVHDALSMSVDEQVNLD  360
            IHHRVKNNLQTVAALLRLQARRT+NAEGREALIESVRRVSSIALVHDALSMSVDEQVNLD
Sbjct  300  IHHRVKNNLQTVAALLRLQARRTANAEGREALIESVRRVSSIALVHDALSMSVDEQVNLD  359

Query  361  EVIDRILPIMNDVASVDRPIRINRVGDLGVLDSDRATALIMVITELVQNAIEHAFDPAAA  420
            EVIDRILPIMNDVASVDRPIRINRVGDLGVLDSDRATALIMVITELVQNAIEHAFDPA  
Sbjct  360  EVIDRILPIMNDVASVDRPIRINRVGDLGVLDSDRATALIMVITELVQNAIEHAFDPAVE  419

Query  421  EGSVTIRAERSARWLDVVVHDDGLGLPQGFSLEKSDSLGLQIVRTLVSAELDGSLGMRDA  480
            EGSVTIRAERSARWLDVVVHDDG GLP GFSLE SDSLGLQIVRTLVSAELDG+LGMR A
Sbjct  420  EGSVTIRAERSARWLDVVVHDDGRGLPDGFSLETSDSLGLQIVRTLVSAELDGTLGMRQA  479

Query  481  RERGTDVVLRVPVGRRGRLML  501
              RGTDVVLRVP+GRR RL+L
Sbjct  480  PARGTDVVLRVPIGRRARLVL  500


>gi|254819136|ref|ZP_05224137.1| sensor histidine kinase [Mycobacterium intracellulare ATCC 13950]
Length=499

 Score =  818 bits (2112),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 420/501 (84%), Positives = 445/501 (89%), Gaps = 2/501 (0%)

Query  1    MSTLGDLLAEHTVLPGSAVDHLHAVVGEWQLLADLSFADYLMWVRRDDGVLVCVAQCRPN  60
            MSTLGDLLAEHT+LPG+AVDHLHAVVGEWQLLADLSFADYLMWVRRDDGVLVCVAQCRPN
Sbjct  1    MSTLGDLLAEHTMLPGNAVDHLHAVVGEWQLLADLSFADYLMWVRRDDGVLVCVAQCRPN  60

Query  61   TGPTVVHTDAVGTVVAANSMPLVAATFSGGVPGREGAVGQQNSCQHDGHSVEVSPVRFGD  120
            T PTV+ TDAVGT +A+  + LVA TF+ G   R+   GQ+NS     H VE SPVR+G 
Sbjct  61   TAPTVLQTDAVGTAIASERLALVADTFASGTAKRDDVAGQENSWLPGTH-VEASPVRYGG  119

Query  121  QVVAVLTRHQPELAARRRSGHLETAYRLCATDLLRMLAEGTFPDAGDVAMSRSSPRAGDG  180
            QVVAVLT HQ  +AA R SG LE AYR CA DL+ MLAEGTFPDAGDV MSRS+PR GDG
Sbjct  120  QVVAVLTHHQTAVAADRASGQLEIAYRQCAGDLVHMLAEGTFPDAGDVVMSRSTPRVGDG  179

Query  181  FIRLDVDGVVSYASPNALSAYHRMGLTTELEGVNLIDATRPLISDPFEAHEVDEHVQDLL  240
            FIRLDV GVV YASPNALSAYHRMGLT +LEG NLI+ TRPLISDPFEA EV EHV+DL+
Sbjct  180  FIRLDVKGVVDYASPNALSAYHRMGLTADLEGHNLIEVTRPLISDPFEAQEVAEHVRDLV  239

Query  241  AGDGKGMRMEVDAGGATVLLRTLPLVVAGRNVGAAILIRDVTEVKRRDRALISKDATIRE  300
            AG G+ MRMEVDAGGATVLLRTLPLVV G + GAA+LIRDVTEVKRRDRALISKDATIRE
Sbjct  240  AG-GRSMRMEVDAGGATVLLRTLPLVVDGASAGAAVLIRDVTEVKRRDRALISKDATIRE  298

Query  301  IHHRVKNNLQTVAALLRLQARRTSNAEGREALIESVRRVSSIALVHDALSMSVDEQVNLD  360
            IHHRVKNNLQTVAALLRLQARRT+NAEGREALIESVRRVSSIALVHDALSMSVDEQVNLD
Sbjct  299  IHHRVKNNLQTVAALLRLQARRTANAEGREALIESVRRVSSIALVHDALSMSVDEQVNLD  358

Query  361  EVIDRILPIMNDVASVDRPIRINRVGDLGVLDSDRATALIMVITELVQNAIEHAFDPAAA  420
            EVIDRILPIMNDVASVDRPIRINRVGDLGVLDSDRATALIMVITELVQNAIEHAFDPA  
Sbjct  359  EVIDRILPIMNDVASVDRPIRINRVGDLGVLDSDRATALIMVITELVQNAIEHAFDPAVE  418

Query  421  EGSVTIRAERSARWLDVVVHDDGLGLPQGFSLEKSDSLGLQIVRTLVSAELDGSLGMRDA  480
            EGSVTIRAERSARWLDVVVHDDG GLP GFSLE SDSLGLQIVRTLVSAELDG+LGM  A
Sbjct  419  EGSVTIRAERSARWLDVVVHDDGRGLPDGFSLETSDSLGLQIVRTLVSAELDGTLGMTQA  478

Query  481  RERGTDVVLRVPVGRRGRLML  501
              RGTDVVLRVP+GRR R++L
Sbjct  479  PARGTDVVLRVPIGRRTRMLL  499


>gi|15827350|ref|NP_301613.1| two-component system sensor kinase [Mycobacterium leprae TN]
 gi|221229828|ref|YP_002503244.1| putative two-component system sensor kinase [Mycobacterium leprae 
Br4923]
 gi|13092899|emb|CAC30313.1| putative two-component system sensor kinase [Mycobacterium leprae]
 gi|219932935|emb|CAR70898.1| putative two-component system sensor kinase [Mycobacterium leprae 
Br4923]
Length=500

 Score =  806 bits (2083),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 410/501 (82%), Positives = 446/501 (90%), Gaps = 1/501 (0%)

Query  1    MSTLGDLLAEHTVLPGSAVDHLHAVVGEWQLLADLSFADYLMWVRRDDGVLVCVAQCRPN  60
            MSTLGDLLAEHTVLPG+AV HLHAVVGEWQLLADLSFADYLMWV RDDGVLVCVAQCRP+
Sbjct  1    MSTLGDLLAEHTVLPGNAVGHLHAVVGEWQLLADLSFADYLMWVSRDDGVLVCVAQCRPH  60

Query  61   TGPTVVHTDAVGTVVAANSMPLVAATFSGGVPGREGAVGQQNSCQHDGHSVEVSPVRFGD  120
            T PTV+ TDAVG+V +A+ +PLV   F+ G    E A GQQ S    G +V  SPVR+GD
Sbjct  61   TAPTVLQTDAVGSVASADMLPLVTEMFTSGAVQHEDAAGQQYSWLPFGRNVAASPVRYGD  120

Query  121  QVVAVLTRHQPELAARRRSGHLETAYRLCATDLLRMLAEGTFPDAGDVAMSRSSPRAGDG  180
            QVVAVLT+HQ ELAARRR G+LE AY  CATDLL MLAEGTFPD GDVA+S S+PRAGDG
Sbjct  121  QVVAVLTQHQVELAARRRPGNLEIAYLACATDLLHMLAEGTFPDVGDVAVSHSTPRAGDG  180

Query  181  FIRLDVDGVVSYASPNALSAYHRMGLTTELEGVNLIDATRPLISDPFEAHEVDEHVQDLL  240
            FIRLD +GVV++ASPNALSA+HRMGLT EL+G NL+  TRPL+SDPFEA EV +HVQDLL
Sbjct  181  FIRLDRNGVVAFASPNALSAFHRMGLTAELQGRNLVKVTRPLLSDPFEAQEVAKHVQDLL  240

Query  241  AGDGKGMRMEVDAGGATVLLRTLPLVVAGRNVGAAILIRDVTEVKRRDRALISKDATIRE  300
             G G  MR+EV+AGGATVLLRTLPLVV G +VGAA+L+RDVTEVKRRDRALISKDATIRE
Sbjct  241  DG-GPSMRVEVNAGGATVLLRTLPLVVHGSSVGAAVLVRDVTEVKRRDRALISKDATIRE  299

Query  301  IHHRVKNNLQTVAALLRLQARRTSNAEGREALIESVRRVSSIALVHDALSMSVDEQVNLD  360
            IHHRVKNNLQTVAALLRLQARR +NAEGREALIESVRRVSSIALVHDALSMSVDEQVNLD
Sbjct  300  IHHRVKNNLQTVAALLRLQARRMANAEGREALIESVRRVSSIALVHDALSMSVDEQVNLD  359

Query  361  EVIDRILPIMNDVASVDRPIRINRVGDLGVLDSDRATALIMVITELVQNAIEHAFDPAAA  420
            EVIDRILPIMNDVASVDRPIRINRVG+LG+LDSDRATALIMVITELVQNAIEHAFDPA+ 
Sbjct  360  EVIDRILPIMNDVASVDRPIRINRVGNLGMLDSDRATALIMVITELVQNAIEHAFDPASQ  419

Query  421  EGSVTIRAERSARWLDVVVHDDGLGLPQGFSLEKSDSLGLQIVRTLVSAELDGSLGMRDA  480
            EG V I AERSARWLDVVVHDDG GLPQGF+LE+SDSLGLQIVRTLVS+ELDGSLGMR A
Sbjct  420  EGFVAISAERSARWLDVVVHDDGRGLPQGFNLERSDSLGLQIVRTLVSSELDGSLGMRKA  479

Query  481  RERGTDVVLRVPVGRRGRLML  501
              RGTDVVLRVP+GRR RL+L
Sbjct  480  PNRGTDVVLRVPIGRRARLLL  500


>gi|108798353|ref|YP_638550.1| signal transduction histidine kinase [Mycobacterium sp. MCS]
 gi|119867450|ref|YP_937402.1| signal transduction histidine kinase [Mycobacterium sp. KMS]
 gi|108768772|gb|ABG07494.1| signal transduction histidine kinase [Mycobacterium sp. MCS]
 gi|119693539|gb|ABL90612.1| signal transduction histidine kinase [Mycobacterium sp. KMS]
Length=496

 Score =  752 bits (1942),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 393/498 (79%), Positives = 424/498 (86%), Gaps = 5/498 (1%)

Query  1    MSTLGDLLAEHTVLPGSAVDHLHAVVGEWQLLADLSFADYLMWVRRDDGVLVCVAQCRPN  60
            MSTLGDLLAEHTVLPG+AVDHLHAVVGEWQLLADLSFADYLMWVRRDDGVLVCVAQ RPN
Sbjct  1    MSTLGDLLAEHTVLPGNAVDHLHAVVGEWQLLADLSFADYLMWVRRDDGVLVCVAQVRPN  60

Query  61   TGPTVVHTDAVGTVVAANSMPLVAATFSGGVPGREGAVGQQNSCQHDGHSVEVSPVRFGD  120
            T  TV+  DAVGT     +MPLV ATF  G+ GREG   Q ++    G +VE  PVR+ +
Sbjct  61   TAATVLLADAVGTTAIPETMPLVTATFESGIIGREGPAAQNDAP---GLNVEAVPVRYRE  117

Query  121  QVVAVLTRHQPELAARRRSGHLETAYRLCATDLLRMLAEGTFPDAGDVAMSRSSPRAGDG  180
             VVAVLT HQ  LAARR +  LE AY  CA DLL ML+EGTFP+ GD+AMSRSSPR GDG
Sbjct  118  DVVAVLT-HQTALAARRTASPLEVAYLDCAGDLLIMLSEGTFPNVGDLAMSRSSPRVGDG  176

Query  181  FIRLDVDGVVSYASPNALSAYHRMGLTTELEGVNLIDATRPLISDPFEAHEVDEHVQDLL  240
            FIRLD  G V +ASPNA+SAYHRMGLT +LEG NL+  TRPLISDPFEA E+  HV+D L
Sbjct  177  FIRLDGAGNVVFASPNAISAYHRMGLTADLEGHNLVAVTRPLISDPFEAQELANHVRDSL  236

Query  241  AGDGKGMRMEVDAGGATVLLRTLPLVVAGRNVGAAILIRDVTEVKRRDRALISKDATIRE  300
            AG G  MRMEVDAGGA VLLRT+PLVV G  VGAA+LIRDVTEVKRRDRAL+SKDATIRE
Sbjct  237  AG-GSSMRMEVDAGGAAVLLRTMPLVVHGAAVGAAVLIRDVTEVKRRDRALLSKDATIRE  295

Query  301  IHHRVKNNLQTVAALLRLQARRTSNAEGREALIESVRRVSSIALVHDALSMSVDEQVNLD  360
            IHHRVKNNLQTVAALLRLQARRT+NAEGREAL+ESVRRVSSIA VHDALSMSVDE+VNLD
Sbjct  296  IHHRVKNNLQTVAALLRLQARRTNNAEGREALMESVRRVSSIAQVHDALSMSVDEEVNLD  355

Query  361  EVIDRILPIMNDVASVDRPIRINRVGDLGVLDSDRATALIMVITELVQNAIEHAFDPAAA  420
            EV+DRILPIMNDVASV  PIRI R GDLGVLD+DRATALIMVITE+VQNAIEHAFD + A
Sbjct  356  EVVDRILPIMNDVASVGPPIRIKREGDLGVLDADRATALIMVITEVVQNAIEHAFDASTA  415

Query  421  EGSVTIRAERSARWLDVVVHDDGLGLPQGFSLEKSDSLGLQIVRTLVSAELDGSLGMRDA  480
            +GSVTIRAERSARWLDVVVHDDG GLP GFSLEKSD LGLQIVRTLVSAELDGSLGM D 
Sbjct  416  QGSVTIRAERSARWLDVVVHDDGRGLPTGFSLEKSDRLGLQIVRTLVSAELDGSLGMHDV  475

Query  481  RERGTDVVLRVPVGRRGR  498
               GTDVVLRVP+GRRGR
Sbjct  476  PSGGTDVVLRVPIGRRGR  493


>gi|126434018|ref|YP_001069709.1| signal transduction histidine kinase [Mycobacterium sp. JLS]
 gi|126233818|gb|ABN97218.1| signal transduction histidine kinase [Mycobacterium sp. JLS]
Length=496

 Score =  752 bits (1941),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 393/498 (79%), Positives = 424/498 (86%), Gaps = 5/498 (1%)

Query  1    MSTLGDLLAEHTVLPGSAVDHLHAVVGEWQLLADLSFADYLMWVRRDDGVLVCVAQCRPN  60
            MSTLGDLLAEHTVLPG+AVDHLHAVVGEWQLLADLSFADYLMWVRRDDGVLVCVAQ RPN
Sbjct  1    MSTLGDLLAEHTVLPGNAVDHLHAVVGEWQLLADLSFADYLMWVRRDDGVLVCVAQVRPN  60

Query  61   TGPTVVHTDAVGTVVAANSMPLVAATFSGGVPGREGAVGQQNSCQHDGHSVEVSPVRFGD  120
            T  TV+  DAVGT     +MPLV ATF  G+ GREG   Q ++    G +VE  PVR+ +
Sbjct  61   TAATVLLADAVGTTAIPETMPLVTATFESGIIGREGPAAQNDAP---GLNVEAVPVRYRE  117

Query  121  QVVAVLTRHQPELAARRRSGHLETAYRLCATDLLRMLAEGTFPDAGDVAMSRSSPRAGDG  180
             VVAVLT HQ  LAARR +  LE AY  CA DLL ML+EGTFP+ GD+AMSRSSPR GDG
Sbjct  118  DVVAVLT-HQTALAARRTASPLEVAYLDCAGDLLIMLSEGTFPNVGDLAMSRSSPRVGDG  176

Query  181  FIRLDVDGVVSYASPNALSAYHRMGLTTELEGVNLIDATRPLISDPFEAHEVDEHVQDLL  240
            FIRLD  G V +ASPNA+SAYHRMGLT +LEG NL+  TRPLISDPFEA E+  HV+D L
Sbjct  177  FIRLDGAGNVVFASPNAISAYHRMGLTADLEGHNLVAVTRPLISDPFEAQELANHVRDSL  236

Query  241  AGDGKGMRMEVDAGGATVLLRTLPLVVAGRNVGAAILIRDVTEVKRRDRALISKDATIRE  300
            AG G  MRMEVDAGGA VLLRT+PLVV G  VGAA+LIRDVTEVKRRDRAL+SKDATIRE
Sbjct  237  AG-GSSMRMEVDAGGAAVLLRTMPLVVHGAAVGAAVLIRDVTEVKRRDRALLSKDATIRE  295

Query  301  IHHRVKNNLQTVAALLRLQARRTSNAEGREALIESVRRVSSIALVHDALSMSVDEQVNLD  360
            IHHRVKNNLQTVAALLRLQARRT+NAEGREAL+ESVRRVSSIA VHDALSMSVDE+VNLD
Sbjct  296  IHHRVKNNLQTVAALLRLQARRTNNAEGREALMESVRRVSSIAQVHDALSMSVDEEVNLD  355

Query  361  EVIDRILPIMNDVASVDRPIRINRVGDLGVLDSDRATALIMVITELVQNAIEHAFDPAAA  420
            EV+DRILPIMNDVASV  PIRI R GDLGVLD+DRATALIMVITE+VQNAIEHAFD + A
Sbjct  356  EVVDRILPIMNDVASVGPPIRIKREGDLGVLDADRATALIMVITEVVQNAIEHAFDASTA  415

Query  421  EGSVTIRAERSARWLDVVVHDDGLGLPQGFSLEKSDSLGLQIVRTLVSAELDGSLGMRDA  480
            +GSVTIRAERSARWLDVVVHDDG GLP GFSLEKSD LGLQIVRTLVSAELDGSLGM D 
Sbjct  416  QGSVTIRAERSARWLDVVVHDDGRGLPAGFSLEKSDRLGLQIVRTLVSAELDGSLGMHDV  475

Query  481  RERGTDVVLRVPVGRRGR  498
               GTDVVLRVP+GRRGR
Sbjct  476  PSGGTDVVLRVPIGRRGR  493


>gi|315445561|ref|YP_004078440.1| signal transduction histidine kinase [Mycobacterium sp. Spyr1]
 gi|315263864|gb|ADU00606.1| signal transduction histidine kinase [Mycobacterium sp. Spyr1]
Length=496

 Score =  736 bits (1900),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 387/499 (78%), Positives = 424/499 (85%), Gaps = 6/499 (1%)

Query  1    MSTLGDLLAEHTVLPGSAVDHLHAVVGEWQLLADLSFADYLMWVRRDDGVLVCVAQCRPN  60
            MSTLGDLLAEHT+LPG+AVDHLHAVVGEWQLLADLSFADYLMWVRRDDG LVCVAQ RPN
Sbjct  1    MSTLGDLLAEHTILPGNAVDHLHAVVGEWQLLADLSFADYLMWVRRDDGHLVCVAQVRPN  60

Query  61   TGPTVVHTDAVGTVVAANSMPLVAATFSGGVPGREGAVGQQNSCQHDGHSVEVSPVRFGD  120
            T PTV+  DAVGT+  A+ +P+VAA F  G  GR    G+  +    G +VE  PVR G 
Sbjct  61   TAPTVLLADAVGTLAEADDIPIVAAAFRSGDIGRATVDGEFGAS---GLNVEAVPVRHGS  117

Query  121  QVVAVLTRHQPELAARRRSGHLETAYRLCATDLLRMLAEGTFPDAGDVAMSRSSPRAGDG  180
             VVAVLT HQ  LA R+ S  LE AY  CA DLL ML+EGTFP+ GD+AMSRSSPR GDG
Sbjct  118  DVVAVLT-HQTSLAPRQASP-LEAAYVDCAGDLLHMLSEGTFPNVGDLAMSRSSPRVGDG  175

Query  181  FIRLDVDGVVSYASPNALSAYHRMGLTTELEGVNLIDATRPLISDPFEAHEVDEHVQDLL  240
            FIRLD  GVV++ASPNA+SAYHRMGL+ ELEG NL+  TRPLI+D FEA E+  HV+D L
Sbjct  176  FIRLDEAGVVTFASPNAISAYHRMGLSAELEGHNLVTVTRPLIADTFEAQELANHVRDSL  235

Query  241  AGDGKGMRMEVDAGGATVLLRTLPLVVAGRNVGAAILIRDVTEVKRRDRALISKDATIRE  300
            AG G  MRMEVDAGGATVLLRTLPL V G  VGAA+LIRDVTEVKRRDRAL+SKDATIRE
Sbjct  236  AG-GSSMRMEVDAGGATVLLRTLPLGVHGVGVGAAVLIRDVTEVKRRDRALLSKDATIRE  294

Query  301  IHHRVKNNLQTVAALLRLQARRTSNAEGREALIESVRRVSSIALVHDALSMSVDEQVNLD  360
            IHHRVKNNLQTVAALLRLQARRT+N EGREAL+ESVRRVSSIALVHDALSMSVDE+VNLD
Sbjct  295  IHHRVKNNLQTVAALLRLQARRTNNPEGREALMESVRRVSSIALVHDALSMSVDEEVNLD  354

Query  361  EVIDRILPIMNDVASVDRPIRINRVGDLGVLDSDRATALIMVITELVQNAIEHAFDPAAA  420
            EVIDRILPIMNDVA+VD PIRINRVGDLGVLD+DRATAL MVITELVQNA+EHAFD    
Sbjct  355  EVIDRILPIMNDVAAVDSPIRINRVGDLGVLDADRATALTMVITELVQNAMEHAFDAETP  414

Query  421  EGSVTIRAERSARWLDVVVHDDGLGLPQGFSLEKSDSLGLQIVRTLVSAELDGSLGMRDA  480
            +G VTIRA+RSARWLDV+VHDDG GLP+GFSLEKSD LGLQIVRTLVSAELDGSLGM +A
Sbjct  415  QGCVTIRAQRSARWLDVIVHDDGRGLPEGFSLEKSDRLGLQIVRTLVSAELDGSLGMHEA  474

Query  481  RERGTDVVLRVPVGRRGRL  499
             E GTDVVLRVP+GRR R+
Sbjct  475  AEGGTDVVLRVPIGRRVRV  493


>gi|120402780|ref|YP_952609.1| signal transduction histidine kinase [Mycobacterium vanbaalenii 
PYR-1]
 gi|119955598|gb|ABM12603.1| signal transduction histidine kinase [Mycobacterium vanbaalenii 
PYR-1]
Length=496

 Score =  735 bits (1897),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 386/498 (78%), Positives = 420/498 (85%), Gaps = 6/498 (1%)

Query  1    MSTLGDLLAEHTVLPGSAVDHLHAVVGEWQLLADLSFADYLMWVRRDDGVLVCVAQCRPN  60
            MSTLGDLLAEHTVLPG+AVDHLHAVVGEWQLLADLSFADYLMWVRRDDG+LVCVAQ RPN
Sbjct  1    MSTLGDLLAEHTVLPGNAVDHLHAVVGEWQLLADLSFADYLMWVRRDDGMLVCVAQVRPN  60

Query  61   TGPTVVHTDAVGTVVAANSMPLVAATFSGGVPGREGAVGQQNSCQHDGHSVEVSPVRFGD  120
            T  TV+  DAVGT+  A  +P+VA  F  G  GR    G+  S    G +VE  PVR+ +
Sbjct  61   TAATVLLADAVGTLAEAEDLPIVAEAFQSGTIGRATVEGEFGS---PGLNVEAVPVRYRN  117

Query  121  QVVAVLTRHQPELAARRRSGHLETAYRLCATDLLRMLAEGTFPDAGDVAMSRSSPRAGDG  180
             VVAVLT HQ  LA R+ S  LE AY  CA DLL ML+EGTFP+ GD+AMSRSSPRAGDG
Sbjct  118  DVVAVLT-HQTSLAPRQAS-PLEAAYVDCAGDLLHMLSEGTFPNVGDLAMSRSSPRAGDG  175

Query  181  FIRLDVDGVVSYASPNALSAYHRMGLTTELEGVNLIDATRPLISDPFEAHEVDEHVQDLL  240
            FIRLD  GVV++ASPNA+SAYHRMGLT +LEG NL+  TRPLISDPFEA E+  HV+D L
Sbjct  176  FIRLDEAGVVTFASPNAISAYHRMGLTADLEGHNLVSITRPLISDPFEAQELANHVRDSL  235

Query  241  AGDGKGMRMEVDAGGATVLLRTLPLVVAGRNVGAAILIRDVTEVKRRDRALISKDATIRE  300
             G G  MRMEVDAGGATVLLRTLPL V G  +GAA+LIRDVTEVKRRDRAL+SKDATIRE
Sbjct  236  TG-GSSMRMEVDAGGATVLLRTLPLGVHGVAMGAAVLIRDVTEVKRRDRALLSKDATIRE  294

Query  301  IHHRVKNNLQTVAALLRLQARRTSNAEGREALIESVRRVSSIALVHDALSMSVDEQVNLD  360
            IHHRVKNNLQTVAALLRLQARRT+N EGREAL+ESVRRVSSIALVHDALSMSVDE+VNLD
Sbjct  295  IHHRVKNNLQTVAALLRLQARRTNNPEGREALMESVRRVSSIALVHDALSMSVDEEVNLD  354

Query  361  EVIDRILPIMNDVASVDRPIRINRVGDLGVLDSDRATALIMVITELVQNAIEHAFDPAAA  420
            +VIDRILPIMNDVA+VD PIRINRVGDLGVLD+DRATALIMVITELVQNAIEHAFD    
Sbjct  355  QVIDRILPIMNDVAAVDSPIRINRVGDLGVLDADRATALIMVITELVQNAIEHAFDATTP  414

Query  421  EGSVTIRAERSARWLDVVVHDDGLGLPQGFSLEKSDSLGLQIVRTLVSAELDGSLGMRDA  480
            +G VTIRA+RSARWLDVVVHDDG GLP GFSLEKSD LGLQIVRTLVSAELDGSLGM   
Sbjct  415  QGCVTIRAQRSARWLDVVVHDDGRGLPDGFSLEKSDRLGLQIVRTLVSAELDGSLGMHAG  474

Query  481  RERGTDVVLRVPVGRRGR  498
               GTDV+LRVP+GRR R
Sbjct  475  AAGGTDVILRVPIGRRAR  492


>gi|145225264|ref|YP_001135942.1| signal transduction histidine kinase [Mycobacterium gilvum PYR-GCK]
 gi|145217750|gb|ABP47154.1| signal transduction histidine kinase [Mycobacterium gilvum PYR-GCK]
Length=496

 Score =  735 bits (1897),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 387/499 (78%), Positives = 424/499 (85%), Gaps = 6/499 (1%)

Query  1    MSTLGDLLAEHTVLPGSAVDHLHAVVGEWQLLADLSFADYLMWVRRDDGVLVCVAQCRPN  60
            MSTLGDLLAEHT+LPG+AVDHLHAVVGEWQLLADLSFADYLMWVRRDDG LVCVAQ RPN
Sbjct  1    MSTLGDLLAEHTILPGNAVDHLHAVVGEWQLLADLSFADYLMWVRRDDGHLVCVAQVRPN  60

Query  61   TGPTVVHTDAVGTVVAANSMPLVAATFSGGVPGREGAVGQQNSCQHDGHSVEVSPVRFGD  120
            T PTV+  DAVGT+  A+ +P+VAA F  G  GR    G+  +    G +VE  PVR G 
Sbjct  61   TAPTVLLADAVGTLAEADDIPIVAAAFRSGDIGRATVDGEFGA---PGLNVEAVPVRHGS  117

Query  121  QVVAVLTRHQPELAARRRSGHLETAYRLCATDLLRMLAEGTFPDAGDVAMSRSSPRAGDG  180
             VVAVLT HQ  LA R+ S  LE AY  CA DLL ML+EGTFP+ GD+AMSRSSPR GDG
Sbjct  118  DVVAVLT-HQTSLAPRQASP-LEAAYVDCAGDLLHMLSEGTFPNVGDLAMSRSSPRVGDG  175

Query  181  FIRLDVDGVVSYASPNALSAYHRMGLTTELEGVNLIDATRPLISDPFEAHEVDEHVQDLL  240
            FIRLD  GVV++ASPNA+SAYHRMGL+ ELEG NL+  TRPLI+D FEA E+  HV+D L
Sbjct  176  FIRLDEAGVVTFASPNAISAYHRMGLSAELEGHNLVTVTRPLIADTFEAQELANHVRDSL  235

Query  241  AGDGKGMRMEVDAGGATVLLRTLPLVVAGRNVGAAILIRDVTEVKRRDRALISKDATIRE  300
            AG G  MRMEVDAGGATVLLRTLPL V G  VGAA+LIRDVTEVKRRDRAL+SKDATIRE
Sbjct  236  AG-GSSMRMEVDAGGATVLLRTLPLGVHGVGVGAAVLIRDVTEVKRRDRALLSKDATIRE  294

Query  301  IHHRVKNNLQTVAALLRLQARRTSNAEGREALIESVRRVSSIALVHDALSMSVDEQVNLD  360
            IHHRVKNNLQTVAALLRLQARRT+N EGREAL+ESVRRVSSIALVHDALSMSVDE+VNLD
Sbjct  295  IHHRVKNNLQTVAALLRLQARRTNNPEGREALMESVRRVSSIALVHDALSMSVDEEVNLD  354

Query  361  EVIDRILPIMNDVASVDRPIRINRVGDLGVLDSDRATALIMVITELVQNAIEHAFDPAAA  420
            EVIDRILPIMNDVA+VD PIRINRVGDLGVLD+DRATAL MVITELVQNA+EHAFD    
Sbjct  355  EVIDRILPIMNDVAAVDSPIRINRVGDLGVLDADRATALTMVITELVQNAMEHAFDAETP  414

Query  421  EGSVTIRAERSARWLDVVVHDDGLGLPQGFSLEKSDSLGLQIVRTLVSAELDGSLGMRDA  480
            +G VTIRA+RSARWLDV+VHDDG GLP+GFSLEKSD LGLQIVRTLVSAELDGSLGM +A
Sbjct  415  QGCVTIRAQRSARWLDVIVHDDGRGLPEGFSLEKSDRLGLQIVRTLVSAELDGSLGMHEA  474

Query  481  RERGTDVVLRVPVGRRGRL  499
             E GTDVVLRVP+GRR R+
Sbjct  475  AEGGTDVVLRVPIGRRVRV  493


>gi|118468520|ref|YP_886284.1| sensor histidine kinase [Mycobacterium smegmatis str. MC2 155]
 gi|118169807|gb|ABK70703.1| sensor histidine kinase [Mycobacterium smegmatis str. MC2 155]
Length=499

 Score =  731 bits (1887),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 377/498 (76%), Positives = 414/498 (84%), Gaps = 2/498 (0%)

Query  1    MSTLGDLLAEHTVLPGSAVDHLHAVVGEWQLLADLSFADYLMWVRRDDGVLVCVAQCRPN  60
            MSTLGDLLAEHT+LPGSAVDHLHAVVGEWQ+L+DLSFADYLMWVRRDDGVLVCVAQ RPN
Sbjct  1    MSTLGDLLAEHTMLPGSAVDHLHAVVGEWQMLSDLSFADYLMWVRRDDGVLVCVAQIRPN  60

Query  61   TGPTVVHTDAVGTVVAANSMPLVAATFSGGVPGREGAVGQQNSCQHDGHSVEVSPVRFGD  120
            T PTV+  D+VG +   + +P+V   F  G  GR      Q S    G  VE  PVR   
Sbjct  61   TAPTVLLADSVGKLAGPDDLPVVTMAFESGAIGRGSDKAGQGSRTRPGLDVEAVPVRHQG  120

Query  121  QVVAVLTRHQPELAARRRSGHLETAYRLCATDLLRMLAEGTFPDAGDVAMSRSSPRAGDG  180
            QVVAVLT HQ  LA RR +  LE AY  CA DLL MLAEGTFP+ GD+AMSRSSPR GDG
Sbjct  121  QVVAVLT-HQTALAERRLTSPLEGAYLDCANDLLHMLAEGTFPNIGDLAMSRSSPRVGDG  179

Query  181  FIRLDVDGVVSYASPNALSAYHRMGLTTELEGVNLIDATRPLISDPFEAHEVDEHVQDLL  240
            FIRL+  G V +ASPNA+SAYHRMGL +EL+G NL+  TRPLISDPFEA E+  H++D L
Sbjct  180  FIRLNEGGEVVFASPNAISAYHRMGLNSELDGHNLVAITRPLISDPFEAQELANHIRDSL  239

Query  241  AGDGKGMRMEVDAGGATVLLRTLPLVVAGRNVGAAILIRDVTEVKRRDRALISKDATIRE  300
            AG G  MRMEVDA GA +LLRTLPLV  G+++GAA+LIRDVTEVKRRDRAL+SKDATIRE
Sbjct  240  AG-GSSMRMEVDANGAAILLRTLPLVAGGKSLGAAVLIRDVTEVKRRDRALLSKDATIRE  298

Query  301  IHHRVKNNLQTVAALLRLQARRTSNAEGREALIESVRRVSSIALVHDALSMSVDEQVNLD  360
            IHHRVKNNLQTVAALLRLQARRTSN E REALIESVRRV+SIALVHDALSMSVDE+VNLD
Sbjct  299  IHHRVKNNLQTVAALLRLQARRTSNEEAREALIESVRRVTSIALVHDALSMSVDEEVNLD  358

Query  361  EVIDRILPIMNDVASVDRPIRINRVGDLGVLDSDRATALIMVITELVQNAIEHAFDPAAA  420
            +V+DRILPIMNDVASVD PIRINRVG+LGVLD+DRATALIMVITELVQNAIEHAFD    
Sbjct  359  QVVDRILPIMNDVASVDTPIRINRVGNLGVLDADRATALIMVITELVQNAIEHAFDAKTE  418

Query  421  EGSVTIRAERSARWLDVVVHDDGLGLPQGFSLEKSDSLGLQIVRTLVSAELDGSLGMRDA  480
            +G VTI+AERSARWLDVVVHDDG GLP GFSLEKSD LGLQIVRTLV+AELDGSLGM D 
Sbjct  419  QGCVTIKAERSARWLDVVVHDDGRGLPVGFSLEKSDRLGLQIVRTLVTAELDGSLGMHDV  478

Query  481  RERGTDVVLRVPVGRRGR  498
               GTDVVLRVP+GRR R
Sbjct  479  PSGGTDVVLRVPIGRRSR  496


>gi|333991573|ref|YP_004524187.1| sensor kinase from two-component regulatory system [Mycobacterium 
sp. JDM601]
 gi|333487541|gb|AEF36933.1| sensor kinase from two-component regulatory system [Mycobacterium 
sp. JDM601]
Length=495

 Score =  701 bits (1810),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 371/499 (75%), Positives = 404/499 (81%), Gaps = 13/499 (2%)

Query  1    MSTLGDLLAEHTVLPGSAVDHLHAVVGEWQLLADLSFADYLMWVRRD---DGVLVCVAQC  57
            MSTLGDLLAEHTVLPG+AVDHLHAVVGEWQLLADLSFADYLMWVRRD    G LVCVAQC
Sbjct  1    MSTLGDLLAEHTVLPGNAVDHLHAVVGEWQLLADLSFADYLMWVRRDADAGGALVCVAQC  60

Query  58   RPNTGPTVVHTDAVGTVVAANSMPLVAATFSGGVPGREGAVGQQNSCQHDGHSVEVSPVR  117
            RPNT PTV+ +DAVGTV AA+ MPLVA  F  G   RE   GQ+N+        E  PVR
Sbjct  61   RPNTAPTVLLSDAVGTVAAADWMPLVAGAFESGAIARESIAGQRNT--------EAVPVR  112

Query  118  FGDQVVAVLTRHQPELAARRRSGHLETAYRLCATDLLRMLAEGTFPDAGDVAMSRSSPRA  177
              D+VVAVLT HQ  L A R    LE AY  CA DL+ ML+EGTFPD GD+A+SRSSPR 
Sbjct  113  HDDRVVAVLT-HQTALRAGREFSRLEAAYLDCAADLVHMLSEGTFPDVGDIAVSRSSPRV  171

Query  178  GDGFIRLDVDGVVSYASPNALSAYHRMGLTTELEGVNLIDATRPLISDPFEAHEVDEHVQ  237
            GDGFIRL VDG VSYASPNA+SAYHRMGL  EL G +L+  TRPLISD FEAHE+ EH+ 
Sbjct  172  GDGFIRLGVDGTVSYASPNAVSAYHRMGLAAELAGHDLVAVTRPLISDTFEAHELAEHIA  231

Query  238  DLLAGDGKGMRMEVDAGGATVLLRTLPLVVAGRNVGAAILIRDVTEVKRRDRALISKDAT  297
            D LAG G  MR EVDA GA VLLRTLPL+V GR  GAA+L+RDVTEVKRRDRAL+SKDAT
Sbjct  232  DSLAG-GSSMRFEVDAAGAVVLLRTLPLIVHGRPAGAAVLVRDVTEVKRRDRALLSKDAT  290

Query  298  IREIHHRVKNNLQTVAALLRLQARRTSNAEGREALIESVRRVSSIALVHDALSMSVDEQV  357
            IREIHHRVKNNLQTVAALLRLQARRT + EGREAL+ESVRRVSSIA+VH+ALSMSVDE V
Sbjct  291  IREIHHRVKNNLQTVAALLRLQARRTISTEGREALLESVRRVSSIAVVHEALSMSVDEVV  350

Query  358  NLDEVIDRILPIMNDVASVDRPIRINRVGDLGVLDSDRATALIMVITELVQNAIEHAFDP  417
            NLDEVIDRILP+MNDVASV+ PI + R G LG LD+DRATAL MVITELVQNAIEHAFD 
Sbjct  351  NLDEVIDRILPMMNDVASVEIPIHVARTGTLGALDADRATALTMVITELVQNAIEHAFDA  410

Query  418  AAAEGSVTIRAERSARWLDVVVHDDGLGLPQGFSLEKSDSLGLQIVRTLVSAELDGSLGM  477
             A    VTIRAERSARWLDVVVHDDG GLP GFSLE +D LGLQIV TLVSAEL+GSL  
Sbjct  411  DADRHDVTIRAERSARWLDVVVHDDGHGLPAGFSLETADRLGLQIVNTLVSAELNGSLTA  470

Query  478  RDARERGTDVVLRVPVGRR  496
            RDA   GT++VLR+PVG R
Sbjct  471  RDAPGGGTEMVLRIPVGSR  489


>gi|169630621|ref|YP_001704270.1| two component sensor kinase [Mycobacterium abscessus ATCC 19977]
 gi|169242588|emb|CAM63616.1| Probable two component sensor kinase [Mycobacterium abscessus]
Length=496

 Score =  701 bits (1809),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 365/501 (73%), Positives = 404/501 (81%), Gaps = 7/501 (1%)

Query  1    MSTLGDLLAEHTVLPGSAVDHLHAVVGEWQLLADLSFADYLMWVRRDDGVLVCVAQCRPN  60
            MSTLGDLLAEHT+LPG AVDHLHAVV EWQLLADLSFADYLMWV RDD   VCVAQCRPN
Sbjct  1    MSTLGDLLAEHTMLPGDAVDHLHAVVAEWQLLADLSFADYLMWVHRDDDAFVCVAQCRPN  60

Query  61   TGPTVVHTDAVGTVVAANSMPLVAATFSGGVPGREGAVGQQNSCQHDGH-SVEVSPVRFG  119
            T PT++  DAVGT+     +PLV A F+ G   RE      +  +H    +VE  PVR G
Sbjct  61   TAPTIIDNDAVGTIAKIADVPLVEAAFASGAIERES---DSDLTEHASELNVEAVPVRCG  117

Query  120  DQVVAVLTRHQPELAARRRSGHLETAYRLCATDLLRMLAEGTFPDAGDVAMSRSSPRAGD  179
            D+ VAVLT HQ  LA+R + G LE AY  CA DLL ML EGTFP+  D AMSRSSPR GD
Sbjct  118  DRTVAVLT-HQTALASRLKKGTLERAYLECAGDLLLMLTEGTFPNVADQAMSRSSPRVGD  176

Query  180  GFIRLDVDGVVSYASPNALSAYHRMGLTTELEGVNLIDATRPLISDPFEAHEVDEHVQDL  239
            GFIRLDV G V YASPNALSAYHRMGL ++L+G NL+D T+PLISDPFE  E+  H++D+
Sbjct  177  GFIRLDVSGGVKYASPNALSAYHRMGLASDLQGHNLMDVTKPLISDPFEGQELAAHIRDV  236

Query  240  LAGDGKGMRMEVDAGGATVLLRTLPLVVAGRNVGAAILIRDVTEVKRRDRALISKDATIR  299
            LAG G  MRMEVDAGGA VL+RTLPL+  G + GA +L RDVTEVKRRDRAL+SKDATIR
Sbjct  237  LAG-GPSMRMEVDAGGAAVLIRTLPLIARGASEGALLLTRDVTEVKRRDRALLSKDATIR  295

Query  300  EIHHRVKNNLQTVAALLRLQARRTSNAEGREALIESVRRVSSIALVHDALSMSVDEQVNL  359
            EIHHRVKNNLQTVAALLRLQARRT N E REAL ESVRRVSSIALVHDALSMSVDE+VNL
Sbjct  296  EIHHRVKNNLQTVAALLRLQARRTPNDEAREALFESVRRVSSIALVHDALSMSVDEEVNL  355

Query  360  DEVIDRILPIMNDVASVDRPIRINRVGDLGVLDSDRATALIMVITELVQNAIEHAFDPAA  419
            DEVIDRI+PIM DVA+VD  +R++R G LGVLDSDRAT LIMVITELVQNAIEHAFD   
Sbjct  356  DEVIDRIMPIMTDVATVDTKVRVSREGALGVLDSDRATPLIMVITELVQNAIEHAFDE-G  414

Query  420  AEGSVTIRAERSARWLDVVVHDDGLGLPQGFSLEKSDSLGLQIVRTLVSAELDGSLGMRD  479
            A+G V IRAERSARWLDVVVHDDG GLP+GFS+E SD LGLQIVRTLVSAE+DGSL MR 
Sbjct  415  AQGQVVIRAERSARWLDVVVHDDGRGLPEGFSVETSDRLGLQIVRTLVSAEIDGSLDMRS  474

Query  480  ARERGTDVVLRVPVGRRGRLM  500
              E GT+ VLRVP+GRR RLM
Sbjct  475  DPEGGTNAVLRVPLGRRARLM  495


>gi|111023307|ref|YP_706279.1| histidine kinase [Rhodococcus jostii RHA1]
 gi|110822837|gb|ABG98121.1| probable histidine kinase [Rhodococcus jostii RHA1]
Length=500

 Score =  590 bits (1521),  Expect = 2e-166, Method: Compositional matrix adjust.
 Identities = 319/506 (64%), Positives = 380/506 (76%), Gaps = 18/506 (3%)

Query  1    MSTLGDLLAEHTVLPGSAVDHLHAVVGEWQLLADLSFADYLMWVRRDD------GVLVCV  54
            MSTL DLLAEHT LPG AVDHL  VVGEWQLLADLSFAD L+WV  D       G ++CV
Sbjct  1    MSTLSDLLAEHTDLPGEAVDHLQRVVGEWQLLADLSFADVLLWVGTDSAATNPTGTVICV  60

Query  55   AQCRPNTGPTVVHTDAVGTVVAANSMPLV-AATFSGGVPGREGAVGQQNSCQHDGHSV--  111
            A CRP T  T    D VGTVV+ +  P V  A   G V      V  ++   H G     
Sbjct  61   AHCRPTTASTAFPEDVVGTVVSESEHPQVLQALLEGRV------VRPEDGGGHAGLPPRR  114

Query  112  EVSPVRFGDQVVAVLTRHQPELAARRRSGHLETAYRLCATDLLRMLAEGTFPDAGDVAMS  171
            E  PVR+  +V+AVL+R    L+ +R    LE AY  CA DL +M+++GTFP     + +
Sbjct  115  EAVPVRWNGEVIAVLSRDT-NLSHQRAQSPLEVAYLDCAEDLCQMISDGTFPIREARSDT  173

Query  172  RSSPRAGDGFIRLDVDGVVSYASPNALSAYHRMGLTTELEGVNLIDATRPLISDPFEAHE  231
             SSPRAGDGFIRLD DG V YASPNALSAYHRMGL+++L G NL   TR L++DPFE+ E
Sbjct  174  NSSPRAGDGFIRLDTDGRVVYASPNALSAYHRMGLSSDLIGQNLAATTRSLVTDPFESQE  233

Query  232  VDEHVQDLLAGDGKGMRMEVDAGGATVLLRTLPLVVAGRNVGAAILIRDVTEVKRRDRAL  291
            V  +++D +A D  G RME++A GATVLLR L L   G+ VGAA+++RDVTEVKRRDRAL
Sbjct  234  VAGYIRDTIA-DKPGRRMEIEARGATVLLRALVLKPGGKRVGAAVVVRDVTEVKRRDRAL  292

Query  292  ISKDATIREIHHRVKNNLQTVAALLRLQARRTSNAEGREALIESVRRVSSIALVHDALSM  351
            +SKDATIREIHHRVKNNLQTVAALLRLQARRT+N E R+AL ESVRRV+SIALVHD LSM
Sbjct  293  LSKDATIREIHHRVKNNLQTVAALLRLQARRTNNEEARQALSESVRRVTSIALVHDTLSM  352

Query  352  SVDEQVNLDEVIDRILPIMNDVASVDRPIRINRVGDLGVLDSDRATALIMVITELVQNAI  411
            SVDE+VNLDEV+DR++PI++DVA+V  PI++ R G  GV  ++RAT L+MV+TELVQNAI
Sbjct  353  SVDEEVNLDEVVDRLVPILSDVATVSTPIKVRREGSFGVFSAERATPLVMVLTELVQNAI  412

Query  412  EHAFDPAAAEGSVTIRAERSARWLDVVVHDDGLGLPQGFSLEKSDSLGLQIVRTLVSAEL  471
            EHAF+P A  G+VT+RAERSARWLDVV+HDDG GLP GFSLE+SD LGLQIVRTLV+AEL
Sbjct  413  EHAFEPGAP-GTVTMRAERSARWLDVVIHDDGRGLPPGFSLERSDRLGLQIVRTLVAAEL  471

Query  472  DGSLGMRDARERGTDVVLRVPVGRRG  497
            +GSLG+    E GTD VLRVP+GRRG
Sbjct  472  NGSLGLHPGPEGGTDAVLRVPLGRRG  497


>gi|226365814|ref|YP_002783597.1| two-component histidine kinase [Rhodococcus opacus B4]
 gi|226244304|dbj|BAH54652.1| putative two-component histidine kinase [Rhodococcus opacus B4]
Length=500

 Score =  589 bits (1518),  Expect = 4e-166, Method: Compositional matrix adjust.
 Identities = 316/503 (63%), Positives = 377/503 (75%), Gaps = 12/503 (2%)

Query  1    MSTLGDLLAEHTVLPGSAVDHLHAVVGEWQLLADLSFADYLMWVRRDD------GVLVCV  54
            MSTL DLLAE+T LPG AVDHL  VVGEWQLLADLSFAD L+WV  D       G ++CV
Sbjct  1    MSTLSDLLAEYTDLPGEAVDHLQRVVGEWQLLADLSFADVLLWVGADSASTDPTGTVICV  60

Query  55   AQCRPNTGPTVVHTDAVGTVVAANSMPLVAATFSGGVPGREGAVGQQNSCQHDGHSVEVS  114
            A CRP T  T    D VGTVV+ +  P V      G   R    G        G +V   
Sbjct  61   AHCRPTTASTAFPEDVVGTVVSESEHPQVLQALLEGNVVRPEDGGGHAGLPPRGEAV---  117

Query  115  PVRFGDQVVAVLTRHQPELAARRRSGHLETAYRLCATDLLRMLAEGTFPDAGDVAMSRSS  174
            PVR+  +V+AVL+R    L+ +R    LE AY  CA DL +M+++GTFP     + + SS
Sbjct  118  PVRWNGEVIAVLSRDT-NLSHQRAQSPLEVAYLDCAEDLCQMISDGTFPIREARSDTNSS  176

Query  175  PRAGDGFIRLDVDGVVSYASPNALSAYHRMGLTTELEGVNLIDATRPLISDPFEAHEVDE  234
            PRAGDGFIRLD DG V YASPNALSAYHRMGL+++L G NL   TR L++DPFE+ EV  
Sbjct  177  PRAGDGFIRLDTDGSVVYASPNALSAYHRMGLSSDLIGQNLAATTRSLVTDPFESQEVAG  236

Query  235  HVQDLLAGDGKGMRMEVDAGGATVLLRTLPLVVAGRNVGAAILIRDVTEVKRRDRALISK  294
            +++D +A D  G RME++A GATVLLR L L   G  VGAA+++RDVTEVKRRDRAL+SK
Sbjct  237  YIRDTIA-DKPGRRMEIEARGATVLLRALVLKPGGNRVGAAVVVRDVTEVKRRDRALLSK  295

Query  295  DATIREIHHRVKNNLQTVAALLRLQARRTSNAEGREALIESVRRVSSIALVHDALSMSVD  354
            DATIREIHHRVKNNLQTVAALLRLQARRT+N E R+AL ESVRRV+SIALVHD LSMSVD
Sbjct  296  DATIREIHHRVKNNLQTVAALLRLQARRTNNEEARQALSESVRRVTSIALVHDTLSMSVD  355

Query  355  EQVNLDEVIDRILPIMNDVASVDRPIRINRVGDLGVLDSDRATALIMVITELVQNAIEHA  414
            E+VNLDEV+DR++PI++DVA+V  PI++ R G  GV  ++RAT L+MV+TELVQNAIEHA
Sbjct  356  EEVNLDEVVDRLVPILSDVATVSTPIKVRREGSFGVFSAERATPLVMVLTELVQNAIEHA  415

Query  415  FDPAAAEGSVTIRAERSARWLDVVVHDDGLGLPQGFSLEKSDSLGLQIVRTLVSAELDGS  474
            F+P AA G+VT+RAERSARWLDVV+HD+G GLP GFSLE+SD LGLQIVRTLV+AEL+GS
Sbjct  416  FEPGAA-GTVTMRAERSARWLDVVIHDNGRGLPPGFSLERSDRLGLQIVRTLVAAELNGS  474

Query  475  LGMRDARERGTDVVLRVPVGRRG  497
            LG+    E GTD VLRVP+GRRG
Sbjct  475  LGLHPGAEGGTDAVLRVPLGRRG  497


>gi|312140652|ref|YP_004007988.1| two component system sensor kinase [Rhodococcus equi 103S]
 gi|325675719|ref|ZP_08155403.1| sensor histidine kinase [Rhodococcus equi ATCC 33707]
 gi|311889991|emb|CBH49309.1| two component system sensor kinase [Rhodococcus equi 103S]
 gi|325553690|gb|EGD23368.1| sensor histidine kinase [Rhodococcus equi ATCC 33707]
Length=503

 Score =  577 bits (1487),  Expect = 2e-162, Method: Compositional matrix adjust.
 Identities = 319/518 (62%), Positives = 375/518 (73%), Gaps = 41/518 (7%)

Query  1    MSTLGDLLAEHTVLPGSAVDHLHAVVGEWQLLADLSFADYLMWVRRD---------DGVL  51
            MSTL DLLAEHT LPG+AVDHL  VVGEWQLLADLSFAD L+WV  +          G +
Sbjct  1    MSTLSDLLAEHTDLPGNAVDHLQQVVGEWQLLADLSFADVLLWVATERPEGTDGAMPGTV  60

Query  52   VCVAQCRPNTGPTVVHTDAVGTVVAANSMPLVAA-------------TFSGGVPGREGAV  98
            VCVAQCRP T  T    DAVG+VV+ +  P V               T+ GG P R  AV
Sbjct  61   VCVAQCRPTTASTAFPDDAVGSVVSESEHPQVLRALVEGEIVSEVDRTWRGGTPLRREAV  120

Query  99   GQQNSCQHDGHSVEVSPVRFGDQVVAVLTRHQPELAARRRSGHLETAYRLCATDLLRMLA  158
                            PVR   +V+AVL+R    LA +R    LE AY  CA DL +M++
Sbjct  121  ----------------PVRCDGEVIAVLSRDT-NLAQQRAQSPLEIAYLDCAADLCQMIS  163

Query  159  EGTFPDAGDVAMSRSSPRAGDGFIRLDVDGVVSYASPNALSAYHRMGLTTELEGVNLIDA  218
            EGTFP+    + + SSPRAGDGFIRLD  G V Y+SPNALSAYHRMGL T+L G +L   
Sbjct  164  EGTFPNPETRSDTNSSPRAGDGFIRLDPAGRVVYSSPNALSAYHRMGLNTDLVGKDLAST  223

Query  219  TRPLISDPFEAHEVDEHVQDLLAGDGKGMRMEVDAGGATVLLRTLPLVVAGRNVGAAILI  278
            TR LI+DPFE+ EV +++   L G   G RME++A GATVLLR L L   G+ VGAA++I
Sbjct  224  TRSLINDPFESQEVADYISGTLGGR-LGHRMEIEARGATVLLRALVLKPRGQVVGAAVVI  282

Query  279  RDVTEVKRRDRALISKDATIREIHHRVKNNLQTVAALLRLQARRTSNAEGREALIESVRR  338
            RDVTEVKRRDRAL+SKDATIREIHHRVKNNLQTVAALLRLQARRT N E R+AL ESVRR
Sbjct  283  RDVTEVKRRDRALLSKDATIREIHHRVKNNLQTVAALLRLQARRTENEEARQALSESVRR  342

Query  339  VSSIALVHDALSMSVDEQVNLDEVIDRILPIMNDVASVDRPIRINRVGDLGVLDSDRATA  398
            V+SIALVHDALSMSVDE+V+LDEV+D ++PI+ DVASV+ PI+I R G LGV  ++RAT 
Sbjct  343  VTSIALVHDALSMSVDEEVDLDEVVDSLVPILADVASVNMPIKIEREGSLGVFSAERATP  402

Query  399  LIMVITELVQNAIEHAFDPAAAEGSVTIRAERSARWLDVVVHDDGLGLPQGFSLEKSDSL  458
            L+MV+TELVQNAIEHAF+P  + G+V +RA+RSARWLDVV+HDDG GLP GFSLEKSD L
Sbjct  403  LVMVLTELVQNAIEHAFEPGES-GTVYLRADRSARWLDVVIHDDGRGLPPGFSLEKSDRL  461

Query  459  GLQIVRTLVSAELDGSLGMRDARERGTDVVLRVPVGRR  496
            GLQIVRTLV AEL GSLG+  + + GTD VLRVP+GRR
Sbjct  462  GLQIVRTLVGAELGGSLGLHPSPDGGTDAVLRVPLGRR  499


>gi|229489533|ref|ZP_04383396.1| sensor histidine kinase [Rhodococcus erythropolis SK121]
 gi|229323630|gb|EEN89388.1| sensor histidine kinase [Rhodococcus erythropolis SK121]
Length=500

 Score =  570 bits (1470),  Expect = 2e-160, Method: Compositional matrix adjust.
 Identities = 310/504 (62%), Positives = 372/504 (74%), Gaps = 16/504 (3%)

Query  1    MSTLGDLLAEHTVLPGSAVDHLHAVVGEWQLLADLSFADYLMWV------RRDDGVLVCV  54
            MSTL DLLAEHT LPG+AVDHL  VVGEWQLLADLSFAD L+WV       R +G ++CV
Sbjct  1    MSTLSDLLAEHTDLPGAAVDHLQRVVGEWQLLADLSFADVLLWVGTESEKNRSEGTVICV  60

Query  55   AQCRPNTGPTVVHTDAVGTVVAANSMPLVAATFSGGVPGREGAVGQQNSCQHDGHSV--E  112
            A CRP T  T    DAVGTVV+ +  P V       V GR   V  ++    +G     E
Sbjct  61   AHCRPTTASTAFPEDAVGTVVSESEHPQVLRAL---VEGR--VVRGEDETWREGMPPRRE  115

Query  113  VSPVRFGDQVVAVLTRHQPELAARRRSGHLETAYRLCATDLLRMLAEGTFPDAGDVAMSR  172
              PVR   +V+AVL+R    L+ +R    LE AY  CA DL +M+++GTFP     + + 
Sbjct  116  AVPVRLDGRVIAVLSR-DTNLSHQRAQSPLELAYLDCAEDLCQMISDGTFPIRESRSDTN  174

Query  173  SSPRAGDGFIRLDVDGVVSYASPNALSAYHRMGLTTELEGVNLIDATRPLISDPFEAHEV  232
            SSPRAGDGFIRLD +G V YASPNALSAYHRMGL+++L G +L   TR L++DPFE+ E 
Sbjct  175  SSPRAGDGFIRLDTEGTVVYASPNALSAYHRMGLSSDLVGQDLAALTRSLVTDPFESQEA  234

Query  233  DEHVQDLLAGDGKGMRMEVDAGGATVLLRTLPLVVAGRNVGAAILIRDVTEVKRRDRALI  292
              +++D LA D  G RME++A GATVLLR L L   GR+VGAA+++RDVTEVKRRDRAL+
Sbjct  235  AGYIRDTLA-DKPGRRMEIEARGATVLLRALVLKPGGRHVGAAVVVRDVTEVKRRDRALL  293

Query  293  SKDATIREIHHRVKNNLQTVAALLRLQARRTSNAEGREALIESVRRVSSIALVHDALSMS  352
            SKDATIREIHHRVKNNLQTVAALLRLQARRT N E R+AL ESVRRV+SIALVHD LSMS
Sbjct  294  SKDATIREIHHRVKNNLQTVAALLRLQARRTGNDEARQALTESVRRVTSIALVHDTLSMS  353

Query  353  VDEQVNLDEVIDRILPIMNDVASVDRPIRINRVGDLGVLDSDRATALIMVITELVQNAIE  412
            VDE+V+LDEVIDR++P+++DVA V  P+ I R G  GV  ++RAT L+MV+TELVQNAIE
Sbjct  354  VDEEVDLDEVIDRLVPMLSDVAGVGVPVTIRREGSFGVFSAERATPLVMVLTELVQNAIE  413

Query  413  HAFDPAAAEGSVTIRAERSARWLDVVVHDDGLGLPQGFSLEKSDSLGLQIVRTLVSAELD  472
            HAFDP    G+VT+ AERSARWLDV++HD+G GLP+ F LEKSD LGLQIVRTL+ AEL 
Sbjct  414  HAFDPGVT-GTVTLSAERSARWLDVIIHDNGRGLPENFDLEKSDRLGLQIVRTLLGAELG  472

Query  473  GSLGMRDARERGTDVVLRVPVGRR  496
            GSLG+      GTD VLRVP+GRR
Sbjct  473  GSLGLHPGSGGGTDAVLRVPLGRR  496


>gi|226305676|ref|YP_002765636.1| two-component histidine kinase [Rhodococcus erythropolis PR4]
 gi|226184793|dbj|BAH32897.1| putative two-component histidine kinase [Rhodococcus erythropolis 
PR4]
Length=500

 Score =  570 bits (1470),  Expect = 2e-160, Method: Compositional matrix adjust.
 Identities = 310/504 (62%), Positives = 372/504 (74%), Gaps = 16/504 (3%)

Query  1    MSTLGDLLAEHTVLPGSAVDHLHAVVGEWQLLADLSFADYLMWV------RRDDGVLVCV  54
            MSTL DLLAEHT LPG+AVDHL  VVGEWQLLADLSFAD L+WV       R +G ++CV
Sbjct  1    MSTLSDLLAEHTDLPGAAVDHLQRVVGEWQLLADLSFADVLLWVGTESEKNRSEGTVICV  60

Query  55   AQCRPNTGPTVVHTDAVGTVVAANSMPLVAATFSGGVPGREGAVGQQNSCQHDGHSV--E  112
            A CRP T  T    DAVGTVV+ +  P V       V GR   V  ++    +G     E
Sbjct  61   AHCRPTTASTAFPEDAVGTVVSESEHPQVLRAL---VEGR--VVRGEDETWREGMPPRRE  115

Query  113  VSPVRFGDQVVAVLTRHQPELAARRRSGHLETAYRLCATDLLRMLAEGTFPDAGDVAMSR  172
              PVR   +V+AVL+R    L+ +R    LE AY  CA DL +M+++GTFP     + + 
Sbjct  116  AVPVRLDGRVIAVLSR-DTNLSHQRAQSPLELAYLDCAEDLCQMISDGTFPIRESRSDTN  174

Query  173  SSPRAGDGFIRLDVDGVVSYASPNALSAYHRMGLTTELEGVNLIDATRPLISDPFEAHEV  232
            SSPRAGDGFIRLD +G V YASPNALSAYHRMGL+++L G +L   TR L++DPFE+ E 
Sbjct  175  SSPRAGDGFIRLDTEGTVVYASPNALSAYHRMGLSSDLVGQDLAALTRSLVTDPFESQEA  234

Query  233  DEHVQDLLAGDGKGMRMEVDAGGATVLLRTLPLVVAGRNVGAAILIRDVTEVKRRDRALI  292
              +++D LA D  G RME++A GATVLLR L L   GR+VGAA+++RDVTEVKRRDRAL+
Sbjct  235  AGYIRDTLA-DKPGRRMEIEARGATVLLRALVLKPGGRHVGAAVVVRDVTEVKRRDRALL  293

Query  293  SKDATIREIHHRVKNNLQTVAALLRLQARRTSNAEGREALIESVRRVSSIALVHDALSMS  352
            SKDATIREIHHRVKNNLQTVAALLRLQARRT N E R+AL ESVRRV+SIALVHD LSMS
Sbjct  294  SKDATIREIHHRVKNNLQTVAALLRLQARRTGNDEARQALTESVRRVTSIALVHDTLSMS  353

Query  353  VDEQVNLDEVIDRILPIMNDVASVDRPIRINRVGDLGVLDSDRATALIMVITELVQNAIE  412
            VDE+V+LDEVIDR++P+++DVA V  P+ I R G  GV  ++RAT L+MV+TELVQNAIE
Sbjct  354  VDEEVDLDEVIDRLVPMLSDVAGVGVPVAIRREGSFGVFSAERATPLVMVLTELVQNAIE  413

Query  413  HAFDPAAAEGSVTIRAERSARWLDVVVHDDGLGLPQGFSLEKSDSLGLQIVRTLVSAELD  472
            HAFDP    G+VT+ AERSARWLDV++HD+G GLP+ F LEKSD LGLQIVRTL+ AEL 
Sbjct  414  HAFDPGVT-GTVTLSAERSARWLDVIIHDNGRGLPENFDLEKSDRLGLQIVRTLLGAELG  472

Query  473  GSLGMRDARERGTDVVLRVPVGRR  496
            GSLG+      GTD VLRVP+GRR
Sbjct  473  GSLGLHPGSGGGTDAVLRVPLGRR  496


>gi|54026554|ref|YP_120796.1| putative two-component system sensor kinase [Nocardia farcinica 
IFM 10152]
 gi|54018062|dbj|BAD59432.1| putative two-component system sensor kinase [Nocardia farcinica 
IFM 10152]
Length=504

 Score =  570 bits (1468),  Expect = 3e-160, Method: Compositional matrix adjust.
 Identities = 318/504 (64%), Positives = 371/504 (74%), Gaps = 11/504 (2%)

Query  1    MSTLGDLLAEHTVLPGSAVDHLHAVVGEWQLLADLSFADYLMWVR----RDDGVLVCVAQ  56
            M+TL +LLAEHT LPG AVDHL  VVG+WQLLADLSFAD L+WV      D   +VCVAQ
Sbjct  1    MATLSELLAEHTDLPGLAVDHLQRVVGDWQLLADLSFADLLLWVGAGPVEDGADIVCVAQ  60

Query  57   CRPNTGPTVVHTDAVGTVVAANSMPLVAATFSGGVPGREGAVGQQNSCQHDG--HSV-EV  113
            CRP T  TV   D VGTV +    P V      G   R  + G+     H    H+V E 
Sbjct  61   CRPTTAATVHVEDMVGTVASRADHPQVFEALLTGKVVRADSAGEATGVYHPHPVHAVREA  120

Query  114  SPVRFGDQVVAVLTRHQPELAARRRSGHLETAYRLCATDLLRMLAEGTFPDAGDVAMSRS  173
             PVR GD V+AVL+R      +R RS  LE AY  CA DL +M+AEGTFP   D A + S
Sbjct  121  VPVRCGDNVIAVLSRDTDMQRSRVRST-LEIAYVACADDLCQMIAEGTFPTPEDRAATHS  179

Query  174  SPRAGDGFIRLDVDGVVSYASPNALSAYHRMGLTTELEGVNLIDATRPLISDPFEAHEVD  233
            SPRAGDGFIRLD +G+V YASPNALSAYHRMGL ++L G +L + TR LI+DPF+A EV 
Sbjct  180  SPRAGDGFIRLDTEGIVVYASPNALSAYHRMGLQSDLAGQDLAETTRSLITDPFDAQEVV  239

Query  234  EHVQDLLAGDGKGMRMEVDAGGATVLLRTLPLVVAGRNVGAAILIRDVTEVKRRDRALIS  293
              +Q  LAG   G RMEV+A GATVLLRTL L   G+  GAA+L+RDVTEVKRRDRAL+S
Sbjct  240  GDIQAALAGR-TGRRMEVEARGATVLLRTLVLRPHGKLAGAAVLVRDVTEVKRRDRALLS  298

Query  294  KDATIREIHHRVKNNLQTVAALLRLQARRTSNAEGREALIESVRRVSSIALVHDALSMSV  353
            KDATIREIHHRVKNNLQTVAALLRLQARRT N E + AL ESVRRV+SIA VH+ LSMSV
Sbjct  299  KDATIREIHHRVKNNLQTVAALLRLQARRTENEEAQVALTESVRRVTSIASVHEMLSMSV  358

Query  354  DEQVNLDEVIDRILPIMNDVASVDRP-IRINRVGDLGVLDSDRATALIMVITELVQNAIE  412
            DE+V+LDEV+DR+LPIM DVA+V    I++ R G LGV  ++RAT L+MV+TELVQNAIE
Sbjct  359  DEEVDLDEVVDRLLPIMADVATVHTTRIKVRRAGSLGVFSAERATPLVMVLTELVQNAIE  418

Query  413  HAFDPAAAEGSVTIRAERSARWLDVVVHDDGLGLPQGFSLEKSDSLGLQIVRTLVSAELD  472
            HAFD +   G+VTIR+ERSARWLDV++ DDG GLP GFSLE SD LGLQIVRTLV+AEL 
Sbjct  419  HAFD-SGQTGTVTIRSERSARWLDVIISDDGRGLPPGFSLEASDRLGLQIVRTLVTAELG  477

Query  473  GSLGMRDARERGTDVVLRVPVGRR  496
            GS+G+    + GTD VLRVP+GRR
Sbjct  478  GSIGLHPGADVGTDAVLRVPLGRR  501


>gi|333921431|ref|YP_004495012.1| putative two-component histidine kinase [Amycolicicoccus subflavus 
DQS3-9A1]
 gi|333483652|gb|AEF42212.1| Putative two-component histidine kinase [Amycolicicoccus subflavus 
DQS3-9A1]
Length=518

 Score =  561 bits (1446),  Expect = 9e-158, Method: Compositional matrix adjust.
 Identities = 310/524 (60%), Positives = 370/524 (71%), Gaps = 36/524 (6%)

Query  1    MSTLGDLLAEHTVLPGSAVDHLHAVVGEWQLLADLSFADYLMWVRRDD------------  48
            MSTL  LLAEHT LPG AV+HL  +VGEWQL+ADLSF+D LMWV   D            
Sbjct  1    MSTLSALLAEHTDLPGDAVNHLQRLVGEWQLVADLSFSDVLMWVATGDLDDAEGQDDLAG  60

Query  49   GVLVCVAQCRPNTGPTVVHTDAVGTVVAANSMP-LVAATFSGGVPGREGAVGQQNSCQHD  107
               VCVAQCRP T PTV   D VG+ V     P LVAA   G +      + +     ++
Sbjct  61   AKAVCVAQCRPTTSPTVYSHDRVGSSVDWADHPELVAAMLRGEI------LREDTPRWYE  114

Query  108  GHSV--EVSPVRFGDQVVAVLTRHQPELAARRRSGHLETAYRLCATDLLRMLAEGTFPDA  165
            G  +  E  PVR G Q++AVLTR    LA  R    LE AY  C+ DL +M+ +G+FP  
Sbjct  115  GTPLAREAIPVRSGGQIIAVLTRDT-SLAQLRVPSALEMAYIACSADLCQMICDGSFPLR  173

Query  166  GDVAMSRSSPRAGDGFIRLDVDGVVSYASPNALSAYHRMGLTTELEGVNLIDATRPLISD  225
             D+   +SSPRAGDG IR+DV+G V+YASPNALSA+HRMGL+TE+ G NL   TRPLISD
Sbjct  174  EDLVGIQSSPRAGDGLIRIDVEGTVAYASPNALSAFHRMGLSTEIAGQNLSAVTRPLISD  233

Query  226  PFEAHEVDEHVQDLLAGDGKGMRMEVDAGGATVLLRTLPLVVAGRNVGAAILIRDVTEVK  285
            PF+A E    +Q + A +   MRME+DA GATVL R LPL       GA +L+RD+TEVK
Sbjct  234  PFDAQEFGVRLQAVTARESS-MRMEIDARGATVLFRALPLYPQLEPAGALVLVRDITEVK  292

Query  286  RRDRALISKDATIREIHHRVKNNLQTVAALLRLQARRTSNAEGREALIESVRRVSSIALV  345
            RRDRAL+SKDATIREIHHRVKNNLQTVAALLRLQ RRT+N E R+AL ESVRRVSSIALV
Sbjct  293  RRDRALLSKDATIREIHHRVKNNLQTVAALLRLQVRRTTNEEARQALAESVRRVSSIALV  352

Query  346  HDALSMSVDEQVNLDEVIDRILPIMNDVASVDRPIRINRVGDLGVLDSDRATALIMVITE  405
            HD LSMSVDEQVNLD+VIDR++P+M DVA+V  PI + R G LGV+ +D+AT L+MV+TE
Sbjct  353  HDTLSMSVDEQVNLDDVIDRLVPMMVDVATVGMPIAVRREGSLGVMPADKATPLVMVLTE  412

Query  406  LVQNAIEHAFDPAAAE-------------GSVTIRAERSARWLDVVVHDDGLGLPQGFSL  452
            LVQNAIEHAF+    E             G + +RAERSARWLDVV+HD+G GLP+GFSL
Sbjct  413  LVQNAIEHAFNLGVPEDLESVDSSDRDVPGEIVLRAERSARWLDVVIHDNGNGLPEGFSL  472

Query  453  EKSDSLGLQIVRTLVSAELDGSLGMRDARERGTDVVLRVPVGRR  496
            E+SD LGLQIVRTLV+AEL GSLG+ ++   GTD VLRVP+GRR
Sbjct  473  ERSDRLGLQIVRTLVAAELGGSLGLHESEAGGTDAVLRVPLGRR  516


>gi|300789788|ref|YP_003770079.1| two-component system sensor kinase [Amycolatopsis mediterranei 
U32]
 gi|299799302|gb|ADJ49677.1| two-component system sensor kinase [Amycolatopsis mediterranei 
U32]
 gi|340531456|gb|AEK46661.1| two-component system sensor kinase [Amycolatopsis mediterranei 
S699]
Length=506

 Score =  488 bits (1257),  Expect = 9e-136, Method: Compositional matrix adjust.
 Identities = 284/520 (55%), Positives = 347/520 (67%), Gaps = 39/520 (7%)

Query  1    MSTLGDLLAEHTVLPGSAVDHLHAVVGEWQLLADLSFADYLMWV------RRDDGVLVCV  54
            MSTL +LLA++T LPG A DHL  VV EWQLLADLSFAD+L+WV      + D G  VCV
Sbjct  1    MSTLAELLADNTGLPGEAADHLQTVVAEWQLLADLSFADFLLWVPVTEDLQPDGGDFVCV  60

Query  55   AQCRPNTGPTVVHTDAVGTVVAANSMPLVAATFSGGVPGREGAVGQQNSC-QHDGHSV--  111
            A  RP T PT    D VGT       P +A            A+ +   C + D H    
Sbjct  61   AHARPTTAPTAHPEDVVGTRFTVQEHPQLAK-----------AMREVRICREEDPHWYRD  109

Query  112  -----EVSPVRFGDQVVAVLTRHQPELAARRRSGHLETAYRLCATDLLRMLAEGTFPDAG  166
                 E  PVRF D+VVAV++R +  LAA R    LE AY   A DL +M+ +GTFP  G
Sbjct  110  LPMRREAIPVRFHDEVVAVMSR-ETNLAAPRVPSPLEIAYLGSAGDLCQMIVDGTFPPNG  168

Query  167  DVAM-SRSSPRAGDGFIRLDVDGVVSYASPNALSAYHRMGLTTELEGVNLIDATRPLISD  225
              A  + +SPR GDG IRLD  G V +ASPN LSAYHRMG  ++L G  L   TR LI D
Sbjct  169  TNATDTHTSPRVGDGLIRLDSSGTVVFASPNGLSAYHRMGHESDLVGTRLAPLTRSLIRD  228

Query  226  PFEAHEVDEHVQDLLAGDGK-GMRMEVDAG-GATVLLRTLPLVVAGRNVGAAILIRDVTE  283
            PF+A EV   + + L  DGK   R E D+  GA VL R LPL  AG+  GA +L+RDVTE
Sbjct  229  PFDATEVSHRIIEAL--DGKPSSRTEADSRRGAVVLFRALPLRPAGQAAGALVLVRDVTE  286

Query  284  VKRRDRALISKDATIREIHHRVKNNLQTVAALLRLQARRTSNAEGREALIESVRRVSSIA  343
            VKRRDRAL+SKDATIREIHHRVKNNLQTVAALLRLQ+RRTS+ E R AL ESVRRV+SIA
Sbjct  287  VKRRDRALLSKDATIREIHHRVKNNLQTVAALLRLQSRRTSSEEARLALAESVRRVTSIA  346

Query  344  LVHDALSMSVDEQVNLDEVIDRILPIMNDVASVDRPIRINRVGDLGVLDSDRATALIMVI  403
            LVH+ALS+SVDE+V+LD+++D +LP++ +VA+ +  + ++R G  GV+ ++ AT L+MV+
Sbjct  347  LVHEALSISVDERVDLDKLLDNVLPMVGEVATAESQVGLSRKGSFGVVVAEIATPLVMVL  406

Query  404  TELVQNAIEHAFDPAAAEGSVTIRAERSARWLDVVVHDDGLGLPQGFSLEKSDSLGLQIV  463
             ELVQNAIEHAF PA   G V +  ERSARWLDVV+ D+G GLP GFSLE+SD LGLQIV
Sbjct  407  AELVQNAIEHAF-PAGRSGKVELIVERSARWLDVVIRDNGRGLPAGFSLERSDGLGLQIV  465

Query  464  RTLVSAELDGSLGMRDARER-------GTDVVLRVPVGRR  496
            RTLV +EL GSL +R  R         GT+  LR+P+ RR
Sbjct  466  RTLVESELRGSLSLRKVRPETSATRVTGTEAALRIPLSRR  505


>gi|134102861|ref|YP_001108522.1| putative two-component system sensor kinase [Saccharopolyspora 
erythraea NRRL 2338]
 gi|291008747|ref|ZP_06566720.1| putative two-component system sensor kinase [Saccharopolyspora 
erythraea NRRL 2338]
 gi|133915484|emb|CAM05597.1| putative two-component system sensor kinase [Saccharopolyspora 
erythraea NRRL 2338]
Length=497

 Score =  484 bits (1246),  Expect = 1e-134, Method: Compositional matrix adjust.
 Identities = 284/504 (57%), Positives = 350/504 (70%), Gaps = 16/504 (3%)

Query  1    MSTLGDLLAEHTVLPGSAVDHLHAVVGEWQLLADLSFADYLMWVR-----RDDGVLVCVA  55
            MSTL DLLAEHT L G+A DHL  VV EWQLL+DLSFAD+LMWV        +   +CVA
Sbjct  1    MSTLSDLLAEHTGLSGAAADHLQLVVAEWQLLSDLSFADFLMWVPIGPPDAAESRFLCVA  60

Query  56   QCRPNTGPTVVHTDAVGTVVAANSMPLVAATFSGGVPGREGAVGQQNSCQHDGHSV--EV  113
            Q RP T PT    D VG+ V  +  P +      G   RE     ++   H G  V  E 
Sbjct  61   QARPTTAPTAHPEDVVGSEVTQDEHPQLRRAAVEGRICRE-----EDPRWHLGVPVRRET  115

Query  114  SPVRFGDQVVAVLTRHQPELAARRRSGHLETAYRLCATDLLRMLAEGTFPDAGDVAMSRS  173
             PV+ G ++VAVL+R    LA  R    LE +Y   A DL +M+A+GTFP         +
Sbjct  116  IPVKLGREIVAVLSRDT-NLAVPRVPSPLEISYLGSAADLCQMVADGTFPTPEPSPDVHT  174

Query  174  SPRAGDGFIRLDVDGVVSYASPNALSAYHRMGLTTELEGVNLIDATRPLISDPFEAHEVD  233
            SPR GDG IRLD  G V +ASPNALSAYHRMG  ++L G  L   TR L++DPF+A EV 
Sbjct  175  SPRVGDGLIRLDASGSVVFASPNALSAYHRMGHASDLVGAQLAPLTRSLLTDPFDADEVS  234

Query  234  EHVQDLLAGDGKGMRMEVDAGGATVLLRTLPLVVAGRNVGAAILIRDVTEVKRRDRALIS  293
            + ++    G    MRME DA GATVL R LPL   G+  GA +L+RDVTEVKRRDRAL+S
Sbjct  235  QRIRRANGGQ-PSMRMEADARGATVLFRALPLHPRGQQAGALVLVRDVTEVKRRDRALLS  293

Query  294  KDATIREIHHRVKNNLQTVAALLRLQARRTSNAEGREALIESVRRVSSIALVHDALSMSV  353
            KDATIREIHHRVKNNLQTVAALLRLQ+RRT N+E R AL ESVRRV+SIALVH+ LSMSV
Sbjct  294  KDATIREIHHRVKNNLQTVAALLRLQSRRTGNSEARLALEESVRRVTSIALVHETLSMSV  353

Query  354  DEQVNLDEVIDRILPIMNDVASVDRPIRINRVGDLGVLDSDRATALIMVITELVQNAIEH  413
            DE+V+LD+V+DR++P+M+DVA+ +  +++ R G  GV+ ++ AT L+MV+TELVQNA EH
Sbjct  354  DERVDLDDVVDRVIPMMSDVAAAETGVKVRRDGRFGVVSAELATPLVMVLTELVQNAFEH  413

Query  414  AFDPAAAEGSVTIRAERSARWLDVVVHDDGLGLPQGFSLEKSDSLGLQIVRTLVSAELDG  473
            AF P    G V ++AERSARWLDVV+ DDG GLP+GFSLE+++ LGLQIVRTLV +EL G
Sbjct  414  AF-PEGQGGEVVVQAERSARWLDVVISDDGRGLPKGFSLERAERLGLQIVRTLVESELRG  472

Query  474  SLGMRD-ARERGTDVVLRVPVGRR  496
            SL +R   R+RGT+ VLRVP+  R
Sbjct  473  SLSLRGRGRQRGTEAVLRVPLKYR  496


>gi|302529993|ref|ZP_07282335.1| histidine kinase [Streptomyces sp. AA4]
 gi|302438888|gb|EFL10704.1| histidine kinase [Streptomyces sp. AA4]
Length=506

 Score =  483 bits (1242),  Expect = 4e-134, Method: Compositional matrix adjust.
 Identities = 280/520 (54%), Positives = 346/520 (67%), Gaps = 39/520 (7%)

Query  1    MSTLGDLLAEHTVLPGSAVDHLHAVVGEWQLLADLSFADYLMWV------RRDDGVLVCV  54
            MSTL DLLAE+T LPG A DHL  VV EWQLLADLSFAD+L+WV      + D G  VCV
Sbjct  1    MSTLSDLLAENTGLPGEAADHLQTVVAEWQLLADLSFADFLLWVPVSAEHQPDGGDFVCV  60

Query  55   AQCRPNTGPTVVHTDAVGTVVAANSMPLVAATFSGGVPGREGAVGQQNSC-QHDGHSV--  111
            A  RP T PT    D VGT    +  P +A            A+ +   C + D H    
Sbjct  61   AHARPTTAPTAHPEDVVGTRFTVDEHPQLAK-----------AMREVKICREEDPHWYRD  109

Query  112  -----EVSPVRFGDQVVAVLTRHQPELAARRRSGHLETAYRLCATDLLRMLAEGTFPDAG  166
                 E  PV FG +V+AVL+R +  LAA R    LE AY   A DL +M+ +GTFP AG
Sbjct  110  LPMRREAVPVSFGGEVIAVLSR-ETNLAAPRVPSPLEIAYLGSAGDLCQMIVDGTFPPAG  168

Query  167  -DVAMSRSSPRAGDGFIRLDVDGVVSYASPNALSAYHRMGLTTELEGVNLIDATRPLISD  225
             +   + +SPR GDG +RLD  G V +ASPN LSAYHRMG  ++L G  L   TR LI D
Sbjct  169  GNQTDTHTSPRVGDGLVRLDQAGTVVFASPNGLSAYHRMGHESDLVGQRLAPLTRSLIRD  228

Query  226  PFEAHEVDEHVQDLLAGDGK-GMRMEVDAG-GATVLLRTLPLVVAGRNVGAAILIRDVTE  283
            PF+A EV   + + L  DGK   R E D+  GA VL R LPL  AG+  GA +L+RDVTE
Sbjct  229  PFDATEVSHRIIEAL--DGKPSTRTEADSKRGAVVLFRALPLRPAGQPAGALVLVRDVTE  286

Query  284  VKRRDRALISKDATIREIHHRVKNNLQTVAALLRLQARRTSNAEGREALIESVRRVSSIA  343
            VKRRDRAL+SKDATIREIHHRVKNNLQTVAALLRLQ+RRT++ E R AL ESVRRVSSIA
Sbjct  287  VKRRDRALMSKDATIREIHHRVKNNLQTVAALLRLQSRRTTSEEARLALGESVRRVSSIA  346

Query  344  LVHDALSMSVDEQVNLDEVIDRILPIMNDVASVDRPIRINRVGDLGVLDSDRATALIMVI  403
            +VH+ALS+SVDE+V+LD+++D +LP++ +VA+ +  + + R G  GV+ ++ AT L+MV+
Sbjct  347  MVHEALSISVDERVDLDKLLDNVLPMVGEVATAESKVGMTRKGSFGVVVAEIATPLVMVL  406

Query  404  TELVQNAIEHAFDPAAAEGSVTIRAERSARWLDVVVHDDGLGLPQGFSLEKSDSLGLQIV  463
             ELVQNAIEHAF P    G V +  ERSARWLD+++ D+G GLP GFSLE+SD LGLQIV
Sbjct  407  AELVQNAIEHAF-PQGRPGKVELIVERSARWLDILIRDNGRGLPSGFSLERSDGLGLQIV  465

Query  464  RTLVSAELDGSLGMRDARE-------RGTDVVLRVPVGRR  496
            RTLV +EL GSL +R  R         GT+  LR+P+ RR
Sbjct  466  RTLVESELRGSLSLRQVRTDEAGNRVPGTEAALRIPLSRR  505


>gi|256380280|ref|YP_003103940.1| signal transduction histidine kinase [Actinosynnema mirum DSM 
43827]
 gi|255924583|gb|ACU40094.1| signal transduction histidine kinase [Actinosynnema mirum DSM 
43827]
Length=492

 Score =  482 bits (1241),  Expect = 6e-134, Method: Compositional matrix adjust.
 Identities = 279/499 (56%), Positives = 346/499 (70%), Gaps = 11/499 (2%)

Query  1    MSTLGDLLAEHTVLPGSAVDHLHAVVGEWQLLADLSFADYLMWVRRDDGVLVCVAQCRPN  60
            MSTL DLLAEHT L G A DHL  VV EWQLL+DLSFAD+LMWV  DDG  +CVAQ RP 
Sbjct  1    MSTLTDLLAEHTKLSGVAADHLQLVVAEWQLLSDLSFADFLMWVPLDDGTFLCVAQARPT  60

Query  61   TGPTVVHTDAVGTVVAANSMPLVAATFSGGVPGREGAVGQQNSCQHDGHSV--EVSPVRF  118
            T PT    D VG+ V  +  P +    +     RE     ++   H G  V  E  PVR 
Sbjct  61   TAPTAHPEDVVGSTVPVDEHPQLRRAIAEVRICRE-----EDPRWHLGVPVRREAIPVRL  115

Query  119  GDQVVAVLTRHQPELAARRRSGHLETAYRLCATDLLRMLAEGTFPDAGDVAMSRSSPRAG  178
            G +V+AVL+R+   LA  R    LE +Y   A DL +M+A+GTFP         +SPR G
Sbjct  116  GSEVIAVLSRNT-NLAVPRVPSPLEISYLGSAADLCQMIADGTFPTTEPSPDVHTSPRVG  174

Query  179  DGFIRLDVDGVVSYASPNALSAYHRMGLTTELEGVNLIDATRPLISDPFEAHEVDEHVQD  238
            DG +RLD  G V +ASPNALSAYHRMG   +L GV+L   TR LI DPF+A EV + ++ 
Sbjct  175  DGLVRLDSSGAVVFASPNALSAYHRMGHAADLIGVHLAPLTRSLIGDPFDATEVAQRIRA  234

Query  239  LLAGDGKGMRMEVDAG-GATVLLRTLPLVVAGRNVGAAILIRDVTEVKRRDRALISKDAT  297
             L G    MR+E ++  GA VL R LPL   G   GA +L RDVTEV+RRDRAL+SKDAT
Sbjct  235  ALDGQ-PSMRIEAESRRGAAVLFRALPLRPRGSAAGALVLCRDVTEVRRRDRALMSKDAT  293

Query  298  IREIHHRVKNNLQTVAALLRLQARRTSNAEGREALIESVRRVSSIALVHDALSMSVDEQV  357
            IREIHHRVKNNLQTVAALLRLQ+RRTS+ E REAL ESVRRV+SIALVH+ LSMSVDE+V
Sbjct  294  IREIHHRVKNNLQTVAALLRLQSRRTSSEEAREALAESVRRVTSIALVHETLSMSVDERV  353

Query  358  NLDEVIDRILPIMNDVASVDRPIRINRVGDLGVLDSDRATALIMVITELVQNAIEHAFDP  417
            +LD+V+D+++P+M+DVA+ +  + + R G  G++ ++ AT L+MV+TELVQNA EHA+ P
Sbjct  354  DLDDVVDKVIPMMSDVAATESQVVVRRDGKFGIVQAELATPLVMVLTELVQNAFEHAYSP  413

Query  418  AAAEGSVTIRAERSARWLDVVVHDDGLGLPQGFSLEKSDSLGLQIVRTLVSAELDGSLGM  477
                G V + +ERSA+WLDV++ DDG GLPQGFSLE++D LGLQIVRTLV +EL GSL +
Sbjct  414  -GQRGEVVVHSERSAKWLDVLICDDGRGLPQGFSLERTDRLGLQIVRTLVESELRGSLSL  472

Query  478  RDARERGTDVVLRVPVGRR  496
            R     GT+ VLRVP+  R
Sbjct  473  RRRPRGGTEAVLRVPLRAR  491


>gi|257057041|ref|YP_003134873.1| signal transduction histidine kinase [Saccharomonospora viridis 
DSM 43017]
 gi|256586913|gb|ACU98046.1| signal transduction histidine kinase [Saccharomonospora viridis 
DSM 43017]
Length=512

 Score =  476 bits (1226),  Expect = 3e-132, Method: Compositional matrix adjust.
 Identities = 271/519 (53%), Positives = 341/519 (66%), Gaps = 31/519 (5%)

Query  1    MSTLGDLLAEHTVLPGSAVDHLHAVVGEWQLLADLSFADYLMWVRRDDGV--LVCVAQCR  58
            MSTL +LLA+HT LPG +VDHL  VV EWQLLADLSF+D+LMWV  ++G    VCVAQ R
Sbjct  1    MSTLVELLADHTGLPGESVDHLQRVVAEWQLLADLSFSDFLMWVPVEEGADEFVCVAQVR  60

Query  59   PNTGPTVVHTDAVGTVVAANSMPLVAATFSGGVPGREGAVGQQNSCQHD-GHSVEVSPVR  117
            P TGPT    D VGT   ++  P +          RE    ++     D     E  PVR
Sbjct  61   PTTGPTAHPEDVVGTRFTSDEHPQLCRAMREVRICRE----EEPHWYRDLPMRREAIPVR  116

Query  118  FGDQVVAVLTRHQPELAARRRSGHLETAYRLCATDLLRMLAEGTFPDAGDVAMSRSSPRA  177
             GD V+AVL+R +  LA  R    +E AY   A DL +M+ +GTFP         +SPR 
Sbjct  117  LGDSVIAVLSR-ETNLATPRVPSPMEIAYLGSAADLCQMITDGTFPCPEVDTGVHTSPRV  175

Query  178  GDGFIRLDVDGVVSYASPNALSAYHRMGLTTELEGVNLIDATRPLISDPFEAHEVDEHVQ  237
            GDG +R+D  G V +ASPN  SAYHRMG  ++L G  L+  TR L+ DPF+A +V  H+Q
Sbjct  176  GDGLVRVDQSGTVVFASPNGQSAYHRMGYESDLVGTRLVPLTRSLVRDPFDAADVAHHIQ  235

Query  238  DLLAGDGK-GMRMEVDA-GGATVLLRTLPLVVAGRNVGAAILIRDVTEVKRRDRALISKD  295
            D +  DGK G R EV+   GA VL R LPL  AGR  GA IL+RDVTEVKR DRAL+SKD
Sbjct  236  DAI--DGKPGTRTEVETLPGAVVLFRALPLRPAGRAAGALILVRDVTEVKRLDRALLSKD  293

Query  296  ATIREIHHRVKNNLQTVAALLRLQARRTSNAEGREALIESVRRVSSIALVHDALSMSVDE  355
            ATIREIHHRVKNNLQTVAALLRLQ+RRT + E ++AL ESVRRVSSIA+VH+ALSMSVDE
Sbjct  294  ATIREIHHRVKNNLQTVAALLRLQSRRTQSTEAKQALTESVRRVSSIAMVHEALSMSVDE  353

Query  356  QVNLDEVIDRILPIMNDVASVDRPIRINRVGDLGVLDSDRATALIMVITELVQNAIEHAF  415
            +V+LD + D++LP++ +VA+ +  +R++R G  G + ++ AT L+MV+ ELVQNA+EHAF
Sbjct  354  RVDLDSLFDKVLPMVGEVATAEAQVRVSRTGSFGEVAAEIATPLVMVVAELVQNAVEHAF  413

Query  416  DPAAAEGSVTIRAERSARWLDVVVHDDGLGLPQGFSLEKSDSLGLQIVRTLVSAELDGSL  475
                 +G V I  ERSARWLDV V D+G GLP  FSL+++D LGLQI RTLV +EL GSL
Sbjct  414  S-GGRQGQVNIVVERSARWLDVFVRDNGKGLPPDFSLDRADGLGLQIARTLVESELRGSL  472

Query  476  GMRDARE------------------RGTDVVLRVPVGRR  496
             +R   E                   GT+  +R+P+ RR
Sbjct  473  TLRGRPEDDEAVDDVSADNGNGEKASGTEAAVRIPLSRR  511


>gi|296138837|ref|YP_003646080.1| signal transduction histidine kinase [Tsukamurella paurometabola 
DSM 20162]
 gi|296026971|gb|ADG77741.1| signal transduction histidine kinase [Tsukamurella paurometabola 
DSM 20162]
Length=501

 Score =  467 bits (1202),  Expect = 2e-129, Method: Compositional matrix adjust.
 Identities = 269/504 (54%), Positives = 332/504 (66%), Gaps = 17/504 (3%)

Query  1    MSTLGDLLAEHTVLPGSAVDHLHAVVGEWQLLADLSFADYLMWVRRD-------DGVLVC  53
            M++L DLLA HT LPG A  HL  +V EWQLLADLSFAD  +WVR D       +   VC
Sbjct  1    MASLADLLAIHTDLPGRAARHLQRIVAEWQLLADLSFADLRLWVREDPDESESAEPGYVC  60

Query  54   VAQCRPNTGPTVVHTDAVGTVVAANSMPLVAATFSGGVPGREGAVGQQNSCQHDGHSVEV  113
            +AQCRPNT PTV + D VG  V     P + A + G V  R          +    +V  
Sbjct  61   IAQCRPNTTPTVYNDDGVGVTVEPWQAPTLHAAYEGAVLVRGVTPTWTGPVRVRRQAV--  118

Query  114  SPVRFGDQVVAVLTRHQPELAARRRSGHLETAYRLCATDLLRMLAEGTFPDAGDVAMSRS  173
             PV +G +V+AVLTR    +   R    LE AY  CA DL +M+AEG FP+  D     +
Sbjct  119  -PVLWGGEVMAVLTRDF-NVTHPRTPSPLEVAYTECADDLCKMVAEGAFPEPEDHPTGEA  176

Query  174  SPRAGDGFIRLDVDGVVSYASPNALSAYHRMGLTTELEGVNLIDATRPLISDPFEAHEVD  233
            SPRAGDGFIR+D +G V +ASPNA SAY RMG  TELEG +L D +  L+ D FE+ E+ 
Sbjct  177  SPRAGDGFIRVDQEGRVVFASPNAQSAYRRMGAFTELEGSDLADLSARLVGDRFESEELL  236

Query  234  EHVQDLLAGDGKGMRMEVDAGGATVLLRTLPLVVAGRNVGAAILIRDVTEVKRRDRALIS  293
              +   L   G G R+E+   G TV++R L L   GR  GAA+L+RDV+E+KRRDRALIS
Sbjct  237  AALDGALT-RGDGARVELTTAGVTVVMRVLGLWPGGRPGGAAVLLRDVSELKRRDRALIS  295

Query  294  KDATIREIHHRVKNNLQTVAALLRLQARRTSNAEGREALIESVRRVSSIALVHDALSMSV  353
            KDATIREIHHRVKNNLQ+V+ALLRLQARRT N E + AL ESVRRV+SIALVH+ LSMSV
Sbjct  296  KDATIREIHHRVKNNLQSVSALLRLQARRTRNDEAKRALHESVRRVASIALVHETLSMSV  355

Query  354  DEQVNLDEVIDRILPIMNDVASVD----RPIRINRVGDLGVLDSDRATALIMVITELVQN  409
            DEQVN+D+VIDR++PIM DVA         + + R GD G LD+DRA  L+MV+TEL+QN
Sbjct  356  DEQVNIDDVIDRLIPIMVDVAPASGGATAAVTVLRRGDFGYLDADRAMPLVMVVTELIQN  415

Query  410  AIEHAFDPAAAEGSVTIRAERSARWLDVVVHDDGLGLPQGFSLEKSDSLGLQIVRTLVSA  469
            AIEH +      G+V + A+RS R L V V DDG G+P GF+L +SD LGLQIVRTLV++
Sbjct  416  AIEHGYG-VGETGTVELLADRSTRRLRVTVRDDGAGIPDGFALGESDRLGLQIVRTLVAS  474

Query  470  ELDGSLGMRDARERGTDVVLRVPV  493
            EL G + +      GTD VL VP+
Sbjct  475  ELGGEITLAARTAGGTDAVLTVPL  498


>gi|258651645|ref|YP_003200801.1| signal transduction histidine kinase [Nakamurella multipartita 
DSM 44233]
 gi|258554870|gb|ACV77812.1| signal transduction histidine kinase [Nakamurella multipartita 
DSM 44233]
Length=500

 Score =  459 bits (1180),  Expect = 7e-127, Method: Compositional matrix adjust.
 Identities = 258/507 (51%), Positives = 342/507 (68%), Gaps = 18/507 (3%)

Query  1    MSTLGDLLAEHTVLPGSAVDHLHAVVGEWQLLADLSFADYLMWVRRDDGVLVCVAQCRPN  60
            MSTL D+LAEH+ + G+AV HL AVV EWQLLADLSF+D L+WV  +   L+C AQ RP 
Sbjct  1    MSTLSDVLAEHSSISGAAVAHLQAVVSEWQLLADLSFSDLLLWVPTEPDRLICAAQARPT  60

Query  61   TGPTVVHTDAVGTVVAANSMPLVAATFSGGVPGREGAVGQQNSCQHDGHSV--EVSPVRF  118
            TG T    D V  VVA +   L+   +       E  V  +   +     +  +  PVR 
Sbjct  61   TGVTAFVDDRVKAVVALSEFTLLRRGWE-----EERVVSDEPPLEAPRSWIRRQAIPVRH  115

Query  119  GDQVVAVLTRHQPELAARRRSGHLETAYRLCATDLLRMLAEGTFPDAGDVAMSRSSPRAG  178
              +V+A++ R    L  R  S  LETAY   A DL +M+ +G+FP  G  A   + PRAG
Sbjct  116  LGEVIAIIERDTSSLVGREGS-LLETAYVDAADDLFQMVCDGSFPPPGRPAELHTGPRAG  174

Query  179  DGFIRLDVDGVVSYASPNALSAYHRMGLTTELEGVNLIDATRPLISDPFEAHEVDEHVQD  238
            DG +RLD DG V Y SPNALSAYHR+    E+ G +L   TR LI DPF+A E++  + D
Sbjct  175  DGLLRLDADGKVVYVSPNALSAYHRLAYNGEMLGQSLAQLTRGLIDDPFDASELETRITD  234

Query  239  LLAGDGKGMRMEVDAGGATVLLRTLPLVVAGRNVGAAILIRDVTEVKRRDRALISKDATI  298
             +AG    +RMEV+A  ATVL R LPL   GR  GA +L+RDVTEV+RRDRAL+SKDATI
Sbjct  235  AVAGR-PSLRMEVEAKAATVLFRALPLRPHGRASGALVLVRDVTEVRRRDRALLSKDATI  293

Query  299  REIHHRVKNNLQTVAALLRLQARRTSNAEGREALIESVRRVSSIALVHDALSMSVDEQVN  358
            REIHHRVKNNLQTVAALLR+QARR+++   R+AL ESVRRV+SIA+VH+ LS S D++V+
Sbjct  294  REIHHRVKNNLQTVAALLRMQARRSADPSVRQALGESVRRVASIAMVHETLSTSPDDRVD  353

Query  359  LDEVIDRILPIMNDVASVDRPIRINRVGDLGVLDSDRATALIMVITELVQNAIEHAFDPA  418
            LD+++DR++P+++DVA+ +   R+ RVG  G+L ++ AT L+MV+ E+VQNA++HAF+PA
Sbjct  354  LDQIVDRLVPMISDVAAAETSARVRRVGSFGILGAELATPLVMVLAEVVQNALQHAFEPA  413

Query  419  A------AEGSVTIRAERSARWLDVVVHDDGLGLPQGFSLEKSDSLGLQIVRTLVSAELD  472
                    +  V I  +RSA+ LD+VV D+G+GLP GF++E++  LGLQIVRTLV AEL 
Sbjct  414  PDAPVGDEQAQVRITVDRSAKQLDIVVSDNGVGLPAGFAVEQASGLGLQIVRTLVEAELL  473

Query  473  GSLGMRD-ARERGTDVVLRVPVGRRGR  498
            G++ M D   E GT V + VP+  RGR
Sbjct  474  GTIEMGDRTPEPGTFVRMSVPL--RGR  498


>gi|343927611|ref|ZP_08767079.1| putative two-component histidine kinase [Gordonia alkanivorans 
NBRC 16433]
 gi|343762252|dbj|GAA14005.1| putative two-component histidine kinase [Gordonia alkanivorans 
NBRC 16433]
Length=509

 Score =  456 bits (1174),  Expect = 4e-126, Method: Compositional matrix adjust.
 Identities = 269/510 (53%), Positives = 333/510 (66%), Gaps = 28/510 (5%)

Query  1    MSTLGDLLAEHTVLPGSAVDHLHAVVGEWQLLADLSFADYLMWVRRDDGVLVCVAQCRPN  60
            MSTL DLLAEHT L  +A  HL  +V EWQLLADLSFAD+L+ VR D+G +V VAQCRPN
Sbjct  1    MSTLADLLAEHTTLSDAAAAHLQRLVAEWQLLADLSFADFLLSVRTDEGAVVTVAQCRPN  60

Query  61   TGPTVVHTDAVGTVVAANSMPLVAATFSGGV------PGREGAVGQQNSCQHDGHSVEVS  114
            T  TV  TD VG V+     P V   F          P   GA   +          E  
Sbjct  61   TASTVFPTDEVGRVIDTAVHPQVLRAFDSDKVLRDEDPTWFGATAMRQ---------EAV  111

Query  115  PVRFGDQVVAVLTRHQPELAARRRSGHLETAYRLCATDLLRMLAEGTFPDAGDVAMSRSS  174
            PV F   V+ VLTR   +L   R    LE AY+  A DL +M+A+GTFP         S+
Sbjct  112  PVGFDGAVIGVLTR-AVDLTHPRLPSPLELAYQDSADDLCQMVADGTFPHEEGNPRGLST  170

Query  175  PRAGDGFIRLDVDGVVSYASPNALSAYHRMGLTTELEGVNLIDATRPLISDPFEAHEVDE  234
            PRAGDGFIRLD  G V+Y SPNALSA+HRMG T EL    L D  + L+++PFEA +V  
Sbjct  171  PRAGDGFIRLDRTGTVTYTSPNALSAFHRMGWTAELNHTRLSDVVKQLVTEPFEADDV-A  229

Query  235  HVQDLLAGDGK---------GMRMEVDAGGATVLLRTLPLVVAGRNVGAAILIRDVTEVK  285
             + D+ AG  +         GMR+E DA  ATVL+R +PL   G   G+ +LIRDVTEVK
Sbjct  230  MMLDIAAGVAEVPTGPYRDIGMRVEADARRATVLIRAVPLRPKGEESGSVVLIRDVTEVK  289

Query  286  RRDRALISKDATIREIHHRVKNNLQTVAALLRLQARRTSNAEGREALIESVRRVSSIALV  345
            RRDRALISKDATIREIHHRVKNNLQ+V+ALLRLQARRTSN + REAL E+VRRV+SIALV
Sbjct  290  RRDRALISKDATIREIHHRVKNNLQSVSALLRLQARRTSNTDAREALNEAVRRVASIALV  349

Query  346  HDALSMSVDEQVNLDEVIDRILPIMNDVASVDRPIRINRVGDLGVLDSDRATALIMVITE  405
            H+ LS SVDE+V+LDEV+DR++PI+ DVAS +  + +     LGVL ++ A  L+MV+TE
Sbjct  350  HELLSGSVDEEVDLDEVVDRLVPILVDVASNESRVTVRHRDRLGVLPAELAMPLVMVLTE  409

Query  406  LVQNAIEHAFDPAA-AEGSVTIRAERSARWLDVVVHDDGLGLPQGFSLEKSDSLGLQIVR  464
            L+QNAIEH FD +  ++  + + AER  R L + V D+G GLP+ F L  SD LGLQIV+
Sbjct  410  LIQNAIEHGFDGSPRSDAEIAVIAERDVRNLRIAVRDNGSGLPENFDLATSDHLGLQIVK  469

Query  465  TLVSAELDGSLGMRDARE-RGTDVVLRVPV  493
            TLVS EL G L +R   E  GT+V + +P+
Sbjct  470  TLVSIELGGELDVRPNPEGLGTEVGVHIPL  499


>gi|331698905|ref|YP_004335144.1| signal transduction histidine kinase [Pseudonocardia dioxanivorans 
CB1190]
 gi|326953594|gb|AEA27291.1| signal transduction histidine kinase [Pseudonocardia dioxanivorans 
CB1190]
Length=499

 Score =  450 bits (1158),  Expect = 3e-124, Method: Compositional matrix adjust.
 Identities = 267/507 (53%), Positives = 335/507 (67%), Gaps = 20/507 (3%)

Query  1    MSTLGDLLAEHTVLPGSAVDHLHAVVGEWQLLADLSFADYLMWVRRDDG---------VL  51
            MSTL +LLA HT LPG AVDHL  VV EWQLLAD+SFAD+L+W+   DG           
Sbjct  1    MSTLSELLAAHTQLPGEAVDHLQRVVAEWQLLADMSFADFLLWIPLPDGDHALAGGATEF  60

Query  52   VCVAQCRPNTGPTVVHTDAVGTVVAANSMPLVAATFSGGVPGREGAVGQQNSCQHDGHSV  111
            +CVAQ RP+T PT    D VG  V A   P +      G   RE     ++   H    V
Sbjct  61   LCVAQARPDTAPTAHPEDMVGARVTAADNPQLRRAVVEGRICRE-----EDPRWHLEVPV  115

Query  112  --EVSPVRFGDQVVAVLTRHQPELAARRRSGHLETAYRLCATDLLRMLAEGTFPDAGDVA  169
              E  PVR   +V+AVL+R    LA  R    LE AY   A+DL +M+A+GTFP A  VA
Sbjct  116  RRETIPVRHNGRVLAVLSRDT-NLAMPRVPSPLEIAYLGSASDLCQMIADGTFPPAASVA  174

Query  170  MSRSSPRAGDGFIRLDVDGVVSYASPNALSAYHRMGLTTELEGVNLIDATRPLISDPFEA  229
             + +SPRAGDG IRLD  G+V+YASPNALSAYHRMG  ++L G+ L DATR L+ DPF+A
Sbjct  175  GADTSPRAGDGLIRLDSRGLVAYASPNALSAYHRMGHASDLIGLPLADATRKLVRDPFDA  234

Query  230  HEVDEHVQDLLAGDGKGMRMEVDAGGATVLLRTLPLVVAGRNVGAAILIRDVTEVKRRDR  289
             EV   ++  L+G    +R+E+ A GA +L+R LPL   G   GA +L+RDVT+++RRD 
Sbjct  235  AEVAARIESALSGRSS-LRLEIRARGAVMLVRALPLRPRGDAAGALVLVRDVTDLRRRDL  293

Query  290  ALISKDATIREIHHRVKNNLQTVAALLRLQARRTSNAEGREALIESVRRVSSIALVHDAL  349
            AL+SKDATIREIHHRVKNNLQTVAALLRLQARRTS  E + AL ESVRRVSSIALVH+AL
Sbjct  294  ALLSKDATIREIHHRVKNNLQTVAALLRLQARRTSIPEAKLALAESVRRVSSIALVHEAL  353

Query  350  SMSVDEQVNLDEVIDRILPIMNDVASVDRPIRINRVGDLGVLDSDRATALIMVITELVQN  409
            + SV EQV+LD++ID +LP++ D A+ D   ++ R G  G   +  AT L++V+TELV N
Sbjct  354  AYSVAEQVDLDQLIDTVLPMIGDGATADVRAKVRREGSFGTHPAAMATPLVLVVTELVHN  413

Query  410  AIEHAFDPAAAEGSVTIRAERSARWLDVVVHDDGLGLPQGFSLEKSDSLGLQIVRTLVSA  469
            A+ HAF    A G V + A RSA  L V + DDG GLP GF  + ++ LGLQIVRTL+ +
Sbjct  414  ALRHAFASDQA-GEVVVSARRSAGRLVVAIADDGRGLPDGFDPDGANGLGLQIVRTLLHS  472

Query  470  ELDGSLGMRDARERGTDVVLRVP-VGR  495
            ELD SL +R     GT+ V+ +P VGR
Sbjct  473  ELDSSLQLRPRAGGGTEAVIELPLVGR  499


>gi|262203400|ref|YP_003274608.1| histidine kinase dimerization/phosphoacceptor [Gordonia bronchialis 
DSM 43247]
 gi|262086747|gb|ACY22715.1| histidine kinase dimerization/phosphoacceptor [Gordonia bronchialis 
DSM 43247]
Length=500

 Score =  446 bits (1146),  Expect = 5e-123, Method: Compositional matrix adjust.
 Identities = 266/509 (53%), Positives = 329/509 (65%), Gaps = 27/509 (5%)

Query  1    MSTLGDLLAEHTVLPGSAVDHLHAVVGEWQLLADLSFADYLMWVRRDDGVLVCVAQCRPN  60
            MSTL DLLAEHT L  +A  HL  +V EWQLLADLSFAD+L+ VR D G  + VAQCRPN
Sbjct  1    MSTLADLLAEHTTLSDTAAAHLQRLVAEWQLLADLSFADFLLSVRTDSGAAITVAQCRPN  60

Query  61   TGPTVVHTDAVGTVVAANSMPLVAATFSGGV------PGREGAVGQQNSCQHDGHSVEVS  114
            T  TV  +D VG V+ A+  P V   F          P   GA+  +          E  
Sbjct  61   TASTVFPSDEVGRVIDADVNPQVGRAFDEARILRDEDPTWVGAMAIRR---------EAV  111

Query  115  PVRFGDQVVAVLTRHQPELAARRRSGHLETAYRLCATDLLRMLAEGTFPDAGDVAMSRSS  174
            PV F   V+AVLTR   +L   R    LE AY+  A DL +M+A+GTFP         S+
Sbjct  112  PVGFDGAVIAVLTRAT-DLTHPRLPSPLELAYQDSANDLCQMVADGTFPHEEGNPRGLST  170

Query  175  PRAGDGFIRLDVDGVVSYASPNALSAYHRMGLTTELEGVNLIDATRPLISDPFEAHEVDE  234
            PRAGDGFIRLD  G+V+Y SPNALSA HRMG T EL    L +    L++D FEA +V  
Sbjct  171  PRAGDGFIRLDGHGLVTYTSPNALSAVHRMGWTAELAHTRLSEVITELLTDAFEATDVAS  230

Query  235  HVQDLLAGDGK---------GMRMEVDAGGATVLLRTLPLVVAGRNVGAAILIRDVTEVK  285
             + D+ AG            GMR+E DA  ATVL+R +PL   G   GA +LIRDVTEVK
Sbjct  231  MI-DVAAGAASPPTVPYRDIGMRVEADARRATVLIRAVPLRPRGEVSGAVVLIRDVTEVK  289

Query  286  RRDRALISKDATIREIHHRVKNNLQTVAALLRLQARRTSNAEGREALIESVRRVSSIALV  345
            RRDRALISKDATIREIHHRVKNNLQ+V+ALLRLQARRT+N + R AL E+VRRV+SIALV
Sbjct  290  RRDRALISKDATIREIHHRVKNNLQSVSALLRLQARRTANEDARVALTEAVRRVASIALV  349

Query  346  HDALSMSVDEQVNLDEVIDRILPIMNDVASVDRPIRINRVGDLGVLDSDRATALIMVITE  405
            H+ LS SVDE+V+LDE +DR++PI+ DVAS D+ I +     LGVL ++ A  L+MV+TE
Sbjct  350  HELLSGSVDEEVDLDEAVDRLVPILVDVASGDQTIAVRHRDRLGVLAAEFAMPLVMVLTE  409

Query  406  LVQNAIEHAFDPAAAEGSVTIRAERSARWLDVVVHDDGLGLPQGFSLEKSDSLGLQIVRT  465
            L+QNA EH FD + A+  + I A+R  R L + V D+G GLP  F L  S+ LGLQIV+T
Sbjct  410  LIQNAFEHGFDGSQADAEIDIVAQRDVRTLRIAVRDNGFGLPDDFDLVTSEHLGLQIVQT  469

Query  466  LVSAELDGSLGM-RDARERGTDVVLRVPV  493
            LVS EL G L +  +   RGT+V + +P+
Sbjct  470  LVSIELGGELVVGPNPAGRGTEVAIVIPL  498


>gi|291302627|ref|YP_003513905.1| signal transduction histidine kinase [Stackebrandtia nassauensis 
DSM 44728]
 gi|290571847|gb|ADD44812.1| signal transduction histidine kinase [Stackebrandtia nassauensis 
DSM 44728]
Length=492

 Score =  417 bits (1071),  Expect = 3e-114, Method: Compositional matrix adjust.
 Identities = 240/500 (48%), Positives = 315/500 (63%), Gaps = 14/500 (2%)

Query  1    MSTLGDLLAEHTVLPGSAVDHLHAVVGEWQLLADLSFADYLMW--VRRDDGVLVCVAQCR  58
            MSTLGDL+A HT L  +  +HLH +  EWQLLADLSFAD L+W  VR  +G  +C+AQ R
Sbjct  1    MSTLGDLIAAHTDLSANTSEHLHRLAAEWQLLADLSFADLLLWAPVRDREGCYICLAQVR  60

Query  59   PNTGPTVVHTDAVGTVVAANSMPLVAATFSGGVPGREGAVGQQNSCQHDGHSV--EVSPV  116
            P TGPT    D VG V++      +  +FS G   REG     +   H       E  PV
Sbjct  61   PTTGPTAYDDDQVGRVLSGKDAEHLHTSFSEGRIFREG-----DPVWHGATPARHEAVPV  115

Query  117  RFGD--QVVAVLTRHQPELAARRRSGHLETAYRLCATDLLRMLAEGTFPDAGDVAMSRSS  174
            R  D  QVVAV+ R    L+  R   HLE  Y   A  L+RML +G FP         ++
Sbjct  116  RRRDRQQVVAVVARDT-NLSDTRSPSHLELNYLKTADYLIRMLTDGGFPPPLLPGEPTTA  174

Query  175  PRAGDGFIRLDVDGVVSYASPNALSAYHRMGLTTELEGVNLIDATRPLISDPFEAHEVDE  234
            PR GDG +R+  DG+V YASPNALSAY RMG+T  L G NL + TR L+ DP +A +V  
Sbjct  175  PRVGDGLVRIGADGLVRYASPNALSAYRRMGVTGVLSGENLAELTRGLVDDPEKAKDVHR  234

Query  235  HVQDLLAGDGKGMRMEVDAGGATVLLRTLPLVVAGRNVGAAILIRDVTEVKRRDRALISK  294
             +   L+G+    R E++A GA VL+R LPL   G+  GA +L+RDVTEV+R DR L++K
Sbjct  235  RINRALSGETP-RRKEIEARGAVVLVRALPLRPDGQGAGALVLVRDVTEVRRLDRELVTK  293

Query  295  DATIREIHHRVKNNLQTVAALLRLQARRTSNAEGREALIESVRRVSSIALVHDALSMSVD  354
            +ATIREIHHRVKNNLQTVAALLRLQARR    + R AL ESVRRV+SIALVH+ LS S D
Sbjct  294  EATIREIHHRVKNNLQTVAALLRLQARRVGVPQARAALEESVRRVTSIALVHETLSRSSD  353

Query  355  EQVNLDEVIDRILPIMNDVASVDRPIRINRVGDLGVLDSDRATALIMVITELVQNAIEHA  414
            E V+ D ++D++  +  +VA+ +  +R  RVG+ GVL S+ AT L+M++ ELVQNA+EHA
Sbjct  354  EAVSFDAIVDKVASMAAEVAAPESQVRPRRVGNFGVLPSEVATPLVMILNELVQNAVEHA  413

Query  415  FDPAAAEGSVTIRAERSARWLDVVVHDDGLGLPQGFSLEKSDSLGLQIVRTLVSAELDGS  474
            + P    G V +  +R    L V V+D G GLP+GF ++ +  LGLQIV TL + EL G+
Sbjct  414  YPPGQG-GEVVVDVQREGDRLQVTVYDHGRGLPEGFRIDATHRLGLQIVHTLATGELRGT  472

Query  475  LGMRDARERGTDVVLRVPVG  494
            + + +  + G + VL   +G
Sbjct  473  IKLGNREDGGAEAVLDFTIG  492


>gi|324998110|ref|ZP_08119222.1| signal transduction histidine kinase [Pseudonocardia sp. P1]
Length=511

 Score =  414 bits (1065),  Expect = 2e-113, Method: Compositional matrix adjust.
 Identities = 250/518 (49%), Positives = 320/518 (62%), Gaps = 38/518 (7%)

Query  1    MSTLGDLLAEHTVLPGSAVDHLHAVVGEWQLLADLSFADYLMWVRRDD------------  48
            ++TL +LLAEHT + G   DHL  VVGEWQLLAD+SFAD+L+WV  DD            
Sbjct  6    VTTLSELLAEHTTMGGETADHLQRVVGEWQLLADMSFADFLLWVPLDDLNAVAEDGTTSR  65

Query  49   ---GVLVCVAQCRPNTGPTVVHTDAVGTVVAANSMPLVAATFSGGVPGREGAVGQQNSCQ  105
                  +CVAQ RP T PT    D VG           AAT   G   R  AV +   C+
Sbjct  66   ASTAQFLCVAQARPTTAPTAHPDDVVGRR---------AATVEVGQLRR--AVLEGRICR  114

Query  106  HDGHSV--------EVSPVRFGDQVVAVLTRHQPELAARRRSGHLETAYRLCATDLLRML  157
             D            E  PVR   + VAVL+R    LA  R    LE AY   A+DL +M+
Sbjct  115  DDDPRWHLEVPVRRETIPVRHHGRTVAVLSRDT-NLATPRVPSPLEIAYLGSASDLCQMI  173

Query  158  AEGTFP-DAGDVAMSRSSPRAGDGFIRLDVDGVVSYASPNALSAYHRMGLTTELEGVNLI  216
             +GTFP  +G    +  SPRAGDG +RLDV G V+YASPNALSAYHRMG  +++ G +L 
Sbjct  174  VDGTFPPQSGPPGSAEGSPRAGDGLVRLDVHGNVAYASPNALSAYHRMGHASDVAGADLA  233

Query  217  DATRPLISDPFEAHEVDEHVQDLLAGDGKGMRMEVDAGGATVLLRTLPLVVAGRNVGAAI  276
              T+ L+ DPF+A +V   + D LAG     RMEV    AT+L+R LPL   G   GA +
Sbjct  234  AVTKALVLDPFDAKDVAGRISDALAGT-PSSRMEVKGRRATMLVRALPLRPRGDAAGALV  292

Query  277  LIRDVTEVKRRDRALISKDATIREIHHRVKNNLQTVAALLRLQARRTSNAEGREALIESV  336
            L+RDVT+++RRD AL+SKDATIREIHHRVKNNLQTVAALLRLQ RR+   E   AL E+V
Sbjct  293  LVRDVTDLRRRDAALMSKDATIREIHHRVKNNLQTVAALLRLQGRRSEYPEAGRALEEAV  352

Query  337  RRVSSIALVHDALSMSVDEQVNLDEVIDRILPIMNDVASVDRPIRINRVGDLGVLDSDRA  396
            RRV+SIALVH+AL+ SV E V LDE++ ++LP + D A+ +   R+      G L + +A
Sbjct  353  RRVTSIALVHEALAYSVAETVELDELLPKVLPAIRDGATTESRARVRVDAGFGALPAAKA  412

Query  397  TALIMVITELVQNAIEHAFDPAAAEGSVTIRAERSARWLDVVVHDDGLGLPQGFSLEKSD  456
            T L++V+ ELV NA+ HA+DP  A G V +  +RSA  L+V V DDG G+P  F  EKS 
Sbjct  413  TPLVLVLAELVHNALAHAYDPGIA-GEVVVSPQRSAGRLEVSVADDGHGMPPEFDFEKSK  471

Query  457  SLGLQIVRTLVSAELDGSLGMRDARERGTDVVLRVPVG  494
             LGLQIVRTL+S+EL+ ++ + D    GT  ++RVP+G
Sbjct  472  GLGLQIVRTLLSSELEATITVSDRDGGGTVALIRVPLG  509


>gi|326383292|ref|ZP_08204980.1| histidine kinase dimerization/phosphoacceptor [Gordonia neofelifaecis 
NRRL B-59395]
 gi|326198042|gb|EGD55228.1| histidine kinase dimerization/phosphoacceptor [Gordonia neofelifaecis 
NRRL B-59395]
Length=513

 Score =  412 bits (1059),  Expect = 7e-113, Method: Compositional matrix adjust.
 Identities = 259/516 (51%), Positives = 322/516 (63%), Gaps = 27/516 (5%)

Query  1    MSTLGDLLAEHTVLPGSAVDHLHAVVGEWQLLADLSFADYLM-------WVRRDDGVLVC  53
            M+TL DLLAEHT L  +A +HL  +V EWQLLADLSFADYL+               LV 
Sbjct  1    MATLTDLLAEHTTLSAAAAEHLQRLVAEWQLLADLSFADYLLAVPGEGGVGGPGTSGLVY  60

Query  54   VAQCRPNTGPTVVHTDAVGTVV-----AANSMPLVAATFSGGVPGREGAVGQQNSCQHDG  108
            VAQ RPNT  TV   D VG  V     A  + PL+AA    GV  REG   +  +   + 
Sbjct  61   VAQVRPNTASTVFPRDEVGHRVDLPASAQGANPLMAAALHSGVIEREGIATRFGNVLIER  120

Query  109  HSVEVSPVRFGDQVVAVLTRHQPELAARRRSGHLETAYRLCATDLLRMLAEGTFPDAGDV  168
             ++   PV FG QV+AVL R   + +  R    LE+AYR  A  L RM+ EGTFP     
Sbjct  121  TAI---PVGFGGQVIAVLGRAG-DASDPRPPSPLESAYRDAAEALCRMVVEGTFPLDEAN  176

Query  169  AMSRSSPRAGDGFIRLDVDGVVSYASPNALSAYHRMGLTTELEGVNLIDATRPLISDPFE  228
             +  S+PRAGDGFIR++  G V+YASPNALSA HRMG TT+L G  + D    L++DPFE
Sbjct  177  TLGLSTPRAGDGFIRIEAGGTVTYASPNALSAVHRMGWTTDLGGSRVADVLAALLTDPFE  236

Query  229  AHEVDEHVQDL--------LAGDGKGMRMEVDAGGATVLLRTLPLVVAGRNVGAAILIRD  280
            + +    +           L      +RME+DA  ATVLLR +PL   G++ GA +LIRD
Sbjct  237  SADAAAMIAAASGTVDAARLPSPDMALRMELDARRATVLLRAVPLRSQGQSRGAVLLIRD  296

Query  281  VTEVKRRDRALISKDATIREIHHRVKNNLQTVAALLRLQARRTSNAEGREALIESVRRVS  340
            VTEV+RRD ALISKDATIREIHHRVKNNLQ+V+ALLRLQARR+ N E   AL E+VRRVS
Sbjct  297  VTEVRRRDLALISKDATIREIHHRVKNNLQSVSALLRLQARRSGNPETTAALGEAVRRVS  356

Query  341  SIALVHDALSMSVDEQVNLDEVIDRILPIMNDVASVDRPIR--INRVGDLGVLDSDRATA  398
            SIALVH+ LS SVDE+V+LD V+DR+   + DV   D   R  + R   LGVL +D A  
Sbjct  357  SIALVHEMLSGSVDEEVDLDTVVDRLGSSLVDVWLPDGGTRVAVRRENRLGVLPADLAMP  416

Query  399  LIMVITELVQNAIEHAFDPAAAEGSVTIRAERSARWLDVVVHDDGLGLPQGFSLEKSDSL  458
            L+MV+TE++QN+IEH F        + + A R  R L V V D+G GLP+GF L  SD L
Sbjct  417  LVMVLTEVIQNSIEHGFTAGQEGAEIVVGAVRDVRGLRVTVTDNGCGLPEGFDLAASDRL  476

Query  459  GLQIVRTLVSAELDGSLGMRDARER-GTDVVLRVPV  493
            GLQIVRTLVS +L G + +   R+R GT V L +P+
Sbjct  477  GLQIVRTLVSNDLGGQIEIAPMRDRAGTRVRLDIPL  512


>gi|330469940|ref|YP_004407683.1| histidine kinase dimerization/phosphoacceptor [Verrucosispora 
maris AB-18-032]
 gi|328812911|gb|AEB47083.1| histidine kinase dimerization/phosphoacceptor [Verrucosispora 
maris AB-18-032]
Length=512

 Score =  411 bits (1057),  Expect = 1e-112, Method: Compositional matrix adjust.
 Identities = 246/516 (48%), Positives = 309/516 (60%), Gaps = 28/516 (5%)

Query  1    MSTLGDLLAEHTVLPGSAVDHLHAVVGEWQLLADLSFADYLMWVRRD-DGVLVCVAQCRP  59
            MSTL DL  EHT L  + +DHLH + G+WQLL+DLSFAD L+WV  D +G  +CVAQ RP
Sbjct  1    MSTLRDLAEEHTRLRPADIDHLHRIAGDWQLLSDLSFADLLLWVPVDGEGTFLCVAQVRP  60

Query  60   NTGPTVVHTDAVGTVVAANSMPLVAATFSGGVPGREGAVGQQN--SCQHDGHSVEVSPVR  117
             T PT    D VG +V    +  +   +  G   REG          +H     E  PVR
Sbjct  61   TTAPTAYQDDQVGRIVGGPEVAHLEVAYGQGRIWREGDPVWYGDVPARH-----EAIPVR  115

Query  118  F------GDQVVAVLTRHQPELAARRRSGHLETAYRLCATDLLRMLAEGTFPDAGDVAMS  171
                     +V+AV+ R    L+  R    LE  Y   A DL +M+A+GTFP       +
Sbjct  116  LRAADGESGEVIAVVGRDT-NLSTARTPSQLELNYLTTADDLAQMIADGTFPPPRHPGET  174

Query  172  RSSPRAGDGFIRLDVDGVVSYASPNALSAYHRMGLTTELEGVNLIDATRPLISDPFEAHE  231
             S+PR GDG +RLD  G V+YASPNA SAY R+G  + L G +L    R L SDP E  E
Sbjct  175  TSAPRVGDGLVRLDAGGKVTYASPNAQSAYRRLGYASHLVGEDLAALNRRLASDPLEGTE  234

Query  232  VDEHVQDLLAGDGKGMRMEVDAGGATVLLRTLPLVVAGRNVGAAILIRDVTEVKRRDRAL  291
                +   L G+    R E+DA GAT+L R LPL+ AG  +GA +L+RD+TEV+RRDRAL
Sbjct  235  AANGILAALRGEAP-PRREIDARGATMLTRALPLMPAGVPIGALVLVRDITEVRRRDRAL  293

Query  292  ISKDATIREIHHRVKNNLQTVAALLRLQARRTSNAEGREALIESVRRVSSIALVHDALSM  351
            I+KDATIREIHHRVKNNLQTVAALLRLQARR    E R AL ESVRRV+SIALVH+ LSM
Sbjct  294  ITKDATIREIHHRVKNNLQTVAALLRLQARRVGMPEARVALEESVRRVASIALVHETLSM  353

Query  352  SVDEQVNLDEVIDRILPIMNDVASVDRPIRINRVGDLGVLDSDRATALIMVITELVQNAI  411
            S DE V  D ++DR+     +VA+ +  + + R G  GVL ++ AT+L+MV+ EL+ NA+
Sbjct  354  SSDEAVEFDGIVDRVASAATEVAATEVSVGMRREGSFGVLPAEIATSLVMVLNELLLNAV  413

Query  412  EHAFDPAAAEG------------SVTIRAERSARWLDVVVHDDGLGLPQGFSLEKSDSLG  459
            EH F PA   G             V + A R  + L V V D+G GLP GF  E    LG
Sbjct  414  EHGFPPADEGGPEPVPQEPLAPPQVVVTAHRLRKTLHVTVADNGRGLPAGFDSEGGAKLG  473

Query  460  LQIVRTLVSAELDGSLGMRDARERGTDVVLRVPVGR  495
            LQIVR LV+ EL GS+ +R   E GT+ VL VP+ R
Sbjct  474  LQIVRALVTGELRGSIELRPGAEGGTEAVLTVPLAR  509


>gi|302869691|ref|YP_003838328.1| histidine kinase dimerization/phosphoacceptor [Micromonospora 
aurantiaca ATCC 27029]
 gi|302572550|gb|ADL48752.1| histidine kinase dimerization/phosphoacceptor [Micromonospora 
aurantiaca ATCC 27029]
Length=530

 Score =  405 bits (1042),  Expect = 7e-111, Method: Compositional matrix adjust.
 Identities = 240/520 (47%), Positives = 314/520 (61%), Gaps = 28/520 (5%)

Query  1    MSTLGDLLAEHTVLPGSAVDHLHAVVGEWQLLADLSFADYLMWVRRD-DGVLVCVAQCRP  59
            MSTL DL  EHT L  + +DHLH + G+WQLL+DLSFAD L+WV  D DG  +CVAQ RP
Sbjct  1    MSTLRDLAEEHTALRPADIDHLHRIAGDWQLLSDLSFADLLLWVPVDGDGTFLCVAQVRP  60

Query  60   NTGPTVVHTDAVGTVVAANSMPLVAATFSGGVPGREGAVGQQNSCQHDGHSVEVSPVRFG  119
             T PT    D VG +V    +  +      G   REG             ++ V  +R G
Sbjct  61   TTAPTAYLDDQVGRIVGGAEVAHLEVAHRQGRIWREGDPVWYGDVPARHEAIPVR-LRTG  119

Query  120  D----QVVAVLTRHQPELAARRRSGHLETAYRLCATDLLRMLAEGTFPDAGDVAMSRSSP  175
            D    +V+AV+ R    L+  R    LE  Y   A DL +M+A+GTFP       + S+P
Sbjct  120  DGEAGEVIAVVGRDT-NLSTARTPSQLELNYLTTADDLAQMIADGTFPPPRHPGETTSAP  178

Query  176  RAGDGFIRLDVDGVVSYASPNALSAYHRMGLTTELEGVNLIDATRPLISDPFEAHEVDEH  235
            R GDG +RLD +G V+YASPNA SAY R+G  + L G +L    R L  DP E  +    
Sbjct  179  RVGDGLVRLDANGKVTYASPNAQSAYRRLGYASHLVGEDLAKLHRRLAGDPLEGTDAGNA  238

Query  236  VQDLLAGDGKGMRMEVDAGGATVLLRTLPLVVAGRNVGAAILIRDVTEVKRRDRALISKD  295
            V   L G+    R E+DA GAT+L R LPL+ AG  +GA +L+RD+TEV+RRDRALI+KD
Sbjct  239  VLAALRGEAP-PRREIDARGATMLTRALPLMPAGVPIGALVLVRDITEVRRRDRALITKD  297

Query  296  ATIREIHHRVKNNLQTVAALLRLQARRTSNAEGREALIESVRRVSSIALVHDALSMSVDE  355
            ATIREIHHRVKNNLQTVAALLRLQARR +  E R AL ESVRRV+SIALVH+ LSMS DE
Sbjct  298  ATIREIHHRVKNNLQTVAALLRLQARRVAMPEARVALEESVRRVASIALVHETLSMSSDE  357

Query  356  QVNLDEVIDRILPIMNDVASVDRPIRINRVGDLGVLDSDRATALIMVITELVQNAIEHAF  415
             V  D ++DR+     +VA+ +  + + R G  GVL ++ AT+L+MV+ EL+ NA+EH F
Sbjct  358  AVEFDGIVDRVASAATEVAATEVSVGMRRRGTFGVLPAEIATSLVMVLNELLLNAVEHGF  417

Query  416  DPAAAEGS--------------------VTIRAERSARWLDVVVHDDGLGLPQGFSLEKS  455
             PA  E +                    V + A R+ + L V V D+G GLP+ F  E+ 
Sbjct  418  PPADEEAAAPSPGDAARPEAVVSAPRPEVVVSAHRARKQLHVTVTDNGRGLPEQFDAERG  477

Query  456  DSLGLQIVRTLVSAELDGSLGMRDARERGTDVVLRVPVGR  495
             +LGLQIVR LV+ EL G++ +R+  + GT+  + VP+ R
Sbjct  478  GNLGLQIVRALVTGELRGTIDLRNGADGGTEAAIVVPLAR  517


>gi|315503827|ref|YP_004082714.1| signal transduction histidine kinase [Micromonospora sp. L5]
 gi|315410446|gb|ADU08563.1| signal transduction histidine kinase [Micromonospora sp. L5]
Length=534

 Score =  404 bits (1038),  Expect = 2e-110, Method: Compositional matrix adjust.
 Identities = 240/524 (46%), Positives = 313/524 (60%), Gaps = 32/524 (6%)

Query  1    MSTLGDLLAEHTVLPGSAVDHLHAVVGEWQLLADLSFADYLMWVRRD-DGVLVCVAQCRP  59
            MSTL DL  EHT L  + +DHLH + G+WQLL+DLSFAD L+WV  D DG  +CVAQ RP
Sbjct  1    MSTLRDLAEEHTALRPADIDHLHRIAGDWQLLSDLSFADLLLWVPVDGDGTFLCVAQVRP  60

Query  60   NTGPTVVHTDAVGTVVAANSMPLVAATFSGGVPGREGAVGQQNSCQHDGHSVEVSPVRFG  119
             T PT    D VG +V    +  +      G   REG             ++ V  +R G
Sbjct  61   TTAPTAYLDDQVGRIVGGAEVAHLEVAHRQGRIWREGDPVWYGDVPARHEAIPVR-LRTG  119

Query  120  D----QVVAVLTRHQPELAARRRSGHLETAYRLCATDLLRMLAEGTFPDAGDVAMSRSSP  175
            D    +V+AV+ R    L+  R    LE  Y   A DL +M+A+GTFP       + S+P
Sbjct  120  DGEAGEVIAVVGRDT-NLSTARTPSQLELNYLTTADDLAQMIADGTFPPPRHPGETTSAP  178

Query  176  RAGDGFIRLDVDGVVSYASPNALSAYHRMGLTTELEGVNLIDATRPLISDPFEAHEVDEH  235
            R GDG +RLD +G V+YASPNA SAY R+G  + L G +L    R L  DP E  +    
Sbjct  179  RVGDGLVRLDANGKVTYASPNAQSAYRRLGYASHLVGEDLAKLHRRLAGDPLEGTDAGNA  238

Query  236  VQDLLAGDGKGMRMEVDAGGATVLLRTLPLVVAGRNVGAAILIRDVTEVKRRDRALISKD  295
            V   L G+    R E+DA GAT+L R LPL+ AG  +GA +L+RD+TEV+RRDRALI+KD
Sbjct  239  VLAALRGEAP-PRREIDARGATMLTRALPLMPAGVPIGALVLVRDITEVRRRDRALITKD  297

Query  296  ATIREIHHRVKNNLQTVAALLRLQARRTSNAEGREALIESVRRVSSIALVHDALSMSVDE  355
            ATIREIHHRVKNNLQTVAALLRLQARR +  E R AL ESVRRV+SIALVH+ LSMS DE
Sbjct  298  ATIREIHHRVKNNLQTVAALLRLQARRVAMPEARVALEESVRRVASIALVHETLSMSSDE  357

Query  356  QVNLDEVIDRILPIMNDVASVDRPIRINRVGDLGVLDSDRATALIMVITELVQNAIEHAF  415
             V  D ++DR+     +VA+ +  + + R G  GVL ++ AT+L+MV+ EL+ NA+EH F
Sbjct  358  AVEFDGIVDRVASAATEVAATEVSVGMRRRGTFGVLPAEIATSLVMVLNELLLNAVEHGF  417

Query  416  DPAAAEG------------------------SVTIRAERSARWLDVVVHDDGLGLPQGFS  451
             PA  E                          V + A R+ + L V V D+G GLP+ F 
Sbjct  418  PPADEEAGAPSPSPSPADAARPEAVVSAPRPEVVVSAHRARKQLHVTVTDNGRGLPEQFD  477

Query  452  LEKSDSLGLQIVRTLVSAELDGSLGMRDARERGTDVVLRVPVGR  495
             E+  +LGLQIVR LV+ EL G++ +R+  + GT+  + VP+ R
Sbjct  478  AERGGNLGLQIVRALVTGELRGTIDLRNGADGGTEAAIVVPLAR  521


>gi|317508056|ref|ZP_07965742.1| histidine kinase [Segniliparus rugosus ATCC BAA-974]
 gi|316253652|gb|EFV13036.1| histidine kinase [Segniliparus rugosus ATCC BAA-974]
Length=513

 Score =  403 bits (1035),  Expect = 4e-110, Method: Compositional matrix adjust.
 Identities = 231/509 (46%), Positives = 311/509 (62%), Gaps = 27/509 (5%)

Query  4    LGDLLAEHTVLPGSAVDHLHAVVGEWQLLADLSFADYLMWVRRDDGV-------------  50
            + +LLAE T L G  V+HL  +V EWQL+ADL+FAD+LMWVR+D                
Sbjct  1    MSELLAERTTLTGDQVEHLKRLVAEWQLIADLAFADFLMWVRQDSPTACEGEDPARRESL  60

Query  51   ------LVCVAQCRPNTGPTVVHTDAVGTVVAANSMPLVAATFSGGVPGREGAVGQQNSC  104
                  +VCVAQCRP T  T++  D VGT V     PLV+    G V GR          
Sbjct  61   GDPSERVVCVAQCRPTTAATLLPGDMVGTEVGE---PLVSQLRRGLVEGRIVEPEDPMWL  117

Query  105  QHDGHSVEVSPVRFGDQVVAVLTRHQPELAARRRSGHLETAYRLCATDLLRMLAEGTFPD  164
            ++     EV PVR   +V+AV++R+   L   R SG+LETAY   A  L +M+ +G FPD
Sbjct  118  EYVPTRREVIPVRKDGEVIAVISRYV-NLLQNRSSGNLETAYTSAADALCQMVCDGAFPD  176

Query  165  AGDVAMSRSSPRAGDGFIRLDVDGVVSYASPNALSAYHRMGLTTELEGVNLIDATRPLIS  224
              D       PRAGDGF+RL   G ++Y+SPNA SA  R+G      G +L++  R  + 
Sbjct  177  PLDKG---PGPRAGDGFLRLAETGAITYSSPNASSALRRLGWEGTFMGSDLVEIVRAAVP  233

Query  225  DPFEAHEVDEHVQDLLAGDGKGMRMEVDAGGATVLLRTLPLVVAGRNVGAAILIRDVTEV  284
            D     +    +   L G+    R+EV+A GA  L R + L  +G   GA +L+RDVTE+
Sbjct  234  DSLTVEDTLTALVAALQGEIADARVEVEANGAVTLWRMVGLRQSGEMAGAVVLLRDVTEL  293

Query  285  KRRDRALISKDATIREIHHRVKNNLQTVAALLRLQARRTSNAEGREALIESVRRVSSIAL  344
            + RDRALISKDATIREIHHRVKNNLQ+V+ALLR+QARRT NAE R+AL +SVRR+ SIAL
Sbjct  294  RHRDRALISKDATIREIHHRVKNNLQSVSALLRMQARRTENAEARQALEDSVRRIGSIAL  353

Query  345  VHDALSMSVDEQVNLDEVIDRILPIMNDVASVDRPIRINRVGDLGVLDSDRATALIMVIT  404
            VHDALS+S DE V++DE++D+++ ++ D+ +    + I R G  G L+++RA +L  ++T
Sbjct  354  VHDALSISSDEHVSVDEIVDKLMLLLADLGAPGTSVSIRREGRFGSLEAERAMSLTTILT  413

Query  405  ELVQNAIEHAFDPAAAEGSVTIRAERSARWLDVVVHDDGLGLPQGFSLEKSDSLGLQIVR  464
            EL QNA+EHAF P   +G V IRAER  +WL V V D G+G P+GF  + +  LGL+I  
Sbjct  414  ELAQNALEHAFQP-GDKGEVVIRAERKGKWLSVEVADTGVGFPEGFDPKATKRLGLRIAA  472

Query  465  TLVSAELDGSLGMRDARERGTDVVLRVPV  493
            TL  +EL  SL +  +   G+   L VPV
Sbjct  473  TLAESELQASLELGSSELGGSSARLDVPV  501


>gi|284033089|ref|YP_003383020.1| signal transduction histidine kinase [Kribbella flavida DSM 17836]
 gi|283812382|gb|ADB34221.1| signal transduction histidine kinase [Kribbella flavida DSM 17836]
Length=491

 Score =  402 bits (1033),  Expect = 7e-110, Method: Compositional matrix adjust.
 Identities = 238/498 (48%), Positives = 320/498 (65%), Gaps = 14/498 (2%)

Query  1    MSTLGDLLAEHTVLPGSAVDHLHAVVGEWQLLADLSFADYLMWVRRDDGV-LVCVAQCRP  59
            M +L D++  HT L  + +D L  +V +WQ+LADLSFAD ++W+   +G+     AQ RP
Sbjct  1    MPSLSDVVRNHTTLDQADLDRLQLLVSDWQMLADLSFADLVLWLPDTEGLGFWAGAQMRP  60

Query  60   NTGPTVVHTDAVGTVVAANSMPLVAATFSGGVPGREGAVGQQNSCQHDGHSVEVSPVRFG  119
             TGPT    D VG+ +  +  PL+   + GG   REG    ++        VE  PVR G
Sbjct  61   TTGPTAYLDDIVGSFIPRDRRPLLDQAYDGGRICREGDPEWRDDVPV---RVETIPVRRG  117

Query  120  DQVVAVLTRHQPELAARRRSGHLETAYRLCATDLLRMLAEGTFPDAGDVAMSRSSPRAGD  179
             +V+AV+ R+   L  R  S  LE AY   ATDL RM+ +G FP  G+  +S ++PR GD
Sbjct  118  SRVIAVIARNTNLLGVRTPS-RLEIAYLQSATDLARMITDGIFPYGGERLLS-TTPRVGD  175

Query  180  GFIRLDVDGVVSYASPNALSAYHRMGLTTELEGVNLIDATRPLISDPFEAHEVDEHVQDL  239
            G IR+D  G+V++ASPNALSAY RMGL T+L G  L D +  L+      H+VD+ +  +
Sbjct  176  GCIRVDRHGMVTFASPNALSAYRRMGLVTDLVGSRLKDVSGELL---HSGHKVDDVLASV  232

Query  240  LAGDGKGMRMEVDAGGATVLLRTLPLVVAGRNVGAAILIRDVTEVKRRDRALISKDATIR  299
            L G      +E++   AT+ LR +PL   G +VGA IL+RDVTE++ R+R L++K+ATIR
Sbjct  233  LTGRA-AKELEIENPEATLFLRAIPLRADGEHVGALILLRDVTELRSRERELVTKEATIR  291

Query  300  EIHHRVKNNLQTVAALLRLQARRTSNAEGREALIESVRRVSSIALVHDALSMSVDEQVNL  359
            EIHHRVKNNLQTVAALLR+QARR +  EG+ AL E+VRRV SIA+VH+ LS S DE V+ 
Sbjct  292  EIHHRVKNNLQTVAALLRMQARRITVPEGQAALAEAVRRVGSIAIVHETLSESFDEHVDF  351

Query  360  DEVIDRILPIMNDVASVDRPIRINRVGDLGVLDSDRATALIMVITELVQNAIEHAFDPAA  419
            D+V DR+  ++ DV++V   I   R G  GVLDS+ AT L MV+TEL+QN++EHAF    
Sbjct  352  DDVADRVAAMVADVSTVATQIATRRTGSFGVLDSEVATPLAMVLTELMQNSVEHAFGART  411

Query  420  AE---GSVTIRAERSARWLDVVVHDDGLGLPQGFSLEKSDSLGLQIVRTLVSAELDGSLG  476
             E   G++T+ A+RS   L VV+ DDG GLP+GF  E S +LGL IVRTLV  ELDG L 
Sbjct  412  GEDATGTITLEAQRSVGRLRVVIADDGRGLPEGFDSETSGNLGLSIVRTLVLGELDGVLD  471

Query  477  MRDARE-RGTDVVLRVPV  493
             +   +  GT VVL +PV
Sbjct  472  FQPRTDGPGTTVVLDIPV  489



Lambda     K      H
   0.320    0.135    0.386 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Effective search space used: 1080570311772


  Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
    Posted date:  Sep 5, 2011  4:36 AM
  Number of letters in database: 5,219,829,388
  Number of sequences in database:  15,229,318



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40