BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv3236c Length=385 Score E Sequences producing significant alignments: (Bits) Value gi|15842825|ref|NP_337862.1| cation/proton antiporter, putative ... 716 0.0 gi|254552340|ref|ZP_05142787.1| membrane transporter [Mycobacter... 716 0.0 gi|306782286|ref|ZP_07420623.1| conserved membrane transporter [... 715 0.0 gi|340628215|ref|YP_004746667.1| putative integral membrane tran... 714 0.0 gi|289747054|ref|ZP_06506432.1| integral membrane transporter [M... 714 0.0 gi|339633246|ref|YP_004724888.1| transporter [Mycobacterium afri... 714 0.0 gi|167967987|ref|ZP_02550264.1| conserved integral membrane tran... 704 0.0 gi|15827342|ref|NP_301605.1| transmembrane transport protein [My... 582 3e-164 gi|240170361|ref|ZP_04749020.1| membrane transporter [Mycobacter... 553 2e-155 gi|183981331|ref|YP_001849622.1| membrane transporter [Mycobacte... 546 3e-153 gi|118618050|ref|YP_906382.1| membrane transporter [Mycobacteriu... 545 5e-153 gi|296168974|ref|ZP_06850641.1| sodium/hydrogen exchanger [Mycob... 534 8e-150 gi|342861436|ref|ZP_08718083.1| transporter, monovalent cation:p... 513 2e-143 gi|108799828|ref|YP_640025.1| sodium/hydrogen exchanger [Mycobac... 491 7e-137 gi|126435471|ref|YP_001071162.1| sodium/hydrogen exchanger [Myco... 489 4e-136 gi|118463113|ref|YP_883343.1| transporter, monovalent cation:pro... 481 1e-133 gi|41409447|ref|NP_962283.1| hypothetical protein MAP3349c [Myco... 478 1e-132 gi|118472492|ref|YP_887967.1| transporter monovalent cation:prot... 459 3e-127 gi|134101702|ref|YP_001107363.1| sodium/hydrogen exchanger [Sacc... 370 2e-100 gi|258652832|ref|YP_003201988.1| sodium/hydrogen exchanger [Naka... 367 1e-99 gi|289759376|ref|ZP_06518754.1| integral membrane transporter [M... 322 6e-86 gi|302554587|ref|ZP_07306929.1| transmembrane transporter [Strep... 318 8e-85 gi|296269726|ref|YP_003652358.1| sodium/hydrogen exchanger [Ther... 304 2e-80 gi|88855082|ref|ZP_01129747.1| putative transmembrane transport ... 301 1e-79 gi|21224127|ref|NP_629906.1| transmembrane transport protein [St... 299 6e-79 gi|345000746|ref|YP_004803600.1| sodium/hydrogen exchanger [Stre... 298 8e-79 gi|320009855|gb|ADW04705.1| sodium/hydrogen exchanger [Streptomy... 298 1e-78 gi|256375747|ref|YP_003099407.1| sodium/hydrogen exchanger [Acti... 297 2e-78 gi|269124360|ref|YP_003297730.1| sodium/hydrogen exchanger [Ther... 296 3e-78 gi|284991247|ref|YP_003409801.1| sodium/hydrogen exchanger [Geod... 295 1e-77 gi|326778263|ref|ZP_08237528.1| sodium/hydrogen exchanger [Strep... 294 2e-77 gi|182437609|ref|YP_001825328.1| putative sodium/proton antiport... 294 2e-77 gi|289759375|ref|ZP_06518753.1| integral membrane transporter [M... 294 2e-77 gi|229491296|ref|ZP_04385122.1| sodium/hydrogen exchanger [Rhodo... 293 2e-77 gi|291446010|ref|ZP_06585400.1| transmembrane transport protein ... 293 3e-77 gi|226306301|ref|YP_002766261.1| hypothetical protein RER_28140 ... 293 3e-77 gi|311894509|dbj|BAJ26917.1| putative sodium/proton antiporter [... 293 4e-77 gi|258650663|ref|YP_003199819.1| sodium/hydrogen exchanger [Naka... 292 6e-77 gi|328885719|emb|CCA58958.1| putative transmembrane transport pr... 291 1e-76 gi|239989013|ref|ZP_04709677.1| putative sodium/proton antiporte... 291 1e-76 gi|318060076|ref|ZP_07978799.1| transmembrane transport protein ... 289 7e-76 gi|333028627|ref|ZP_08456691.1| putative Na+/H+ exchanger family... 288 8e-76 gi|318079258|ref|ZP_07986590.1| regulator [Streptomyces sp. SA3_... 285 1e-74 gi|331694697|ref|YP_004330936.1| sodium/hydrogen exchanger [Pseu... 284 2e-74 gi|324998145|ref|ZP_08119257.1| monovalent cation:H+ antiporter-... 284 2e-74 gi|325965052|ref|YP_004242958.1| Kef-type K+ transporter, membra... 282 7e-74 gi|288917341|ref|ZP_06411708.1| sodium/hydrogen exchanger [Frank... 281 1e-73 gi|297155915|gb|ADI05627.1| putative transmembrane transport pro... 281 2e-73 gi|295840290|ref|ZP_06827223.1| Na+/H+ exchanger family protein ... 280 2e-73 gi|290956791|ref|YP_003487973.1| sodium/hydrogen exchange ABC tr... 280 4e-73 >gi|15842825|ref|NP_337862.1| cation/proton antiporter, putative [Mycobacterium tuberculosis CDC1551] gi|31794416|ref|NP_856909.1| integral membrane transport protein [Mycobacterium bovis AF2122/97] gi|57117079|ref|YP_177949.1| integral membrane transport protein [Mycobacterium tuberculosis H37Rv] 49 more sequence titles Length=385 Score = 716 bits (1849), Expect = 0.0, Method: Compositional matrix adjust. Identities = 384/385 (99%), Positives = 385/385 (100%), Gaps = 0/385 (0%) Query 1 VEVSRALLFELGVLLAVLAVLGAVARRFALSPIPVYLLAGLSLGNGGILGVAAAGEFIAT 60 +EVSRALLFELGVLLAVLAVLGAVARRFALSPIPVYLLAGLSLGNGGILGVAAAGEFIAT Sbjct 1 MEVSRALLFELGVLLAVLAVLGAVARRFALSPIPVYLLAGLSLGNGGILGVAAAGEFIAT 60 Query 61 GAPIGVVLLLLALGLEFSATEFASSLRHHLPSAGVDIVLNATPGAVAGWLLGLDGVAILG 120 GAPIGVVLLLLALGLEFSATEFASSLRHHLPSAGVDIVLNATPGAVAGWLLGLDGVAILG Sbjct 61 GAPIGVVLLLLALGLEFSATEFASSLRHHLPSAGVDIVLNATPGAVAGWLLGLDGVAILG 120 Query 121 LAGVTYISSSGVIARLLEDLRRLGNRETPAVLSVLVLEDFAMAAYLPLFAVLATDGSWLE 180 LAGVTYISSSGVIARLLEDLRRLGNRETPAVLSVLVLEDFAMAAYLPLFAVLATDGSWLE Sbjct 121 LAGVTYISSSGVIARLLEDLRRLGNRETPAVLSVLVLEDFAMAAYLPLFAVLATDGSWLE 180 Query 181 AVVGMTVAIAALLGAFAASYRWGHHVGRLVTHPDSEQLLLRVLGITLIVAAVAESLHASA 240 AVVGMTVAIAALLGAFAASYRWGHHVGRLVTHPDSEQLLLRVLGITLIVAAVAESLHASA Sbjct 181 AVVGMTVAIAALLGAFAASYRWGHHVGRLVTHPDSEQLLLRVLGITLIVAAVAESLHASA 240 Query 241 AVGAFLVGLTLTGETADRARMVLTPLRDLFATIFFLGIGLSVDPGKLVSMLPVALALAAV 300 AVGAFLVGLTLTGETADRARMVLTPLRDLFATIFFLGIGLSVDPGKLVSMLPVALALAAV Sbjct 241 AVGAFLVGLTLTGETADRARMVLTPLRDLFATIFFLGIGLSVDPGKLVSMLPVALALAAV 300 Query 301 TAATKVATGMFAARREGVARRGQLRAGTALVARGEFSLIIIGLAGASIPGVAALATAYVF 360 TAATKVATGMFAARREGVARRGQLRAGTALVARGEFSLIIIGLAGASIPGVAALATAYVF Sbjct 301 TAATKVATGMFAARREGVARRGQLRAGTALVARGEFSLIIIGLAGASIPGVAALATAYVF 360 Query 361 VMAIVGPILARYTGGGLPAAAVASN 385 VMAIVGPILARYTGGGLPAAAVASN Sbjct 361 VMAIVGPILARYTGGGLPAAAVASN 385 >gi|254552340|ref|ZP_05142787.1| membrane transporter [Mycobacterium tuberculosis '98-R604 INH-RIF-EM'] Length=385 Score = 716 bits (1847), Expect = 0.0, Method: Compositional matrix adjust. Identities = 383/385 (99%), Positives = 384/385 (99%), Gaps = 0/385 (0%) Query 1 VEVSRALLFELGVLLAVLAVLGAVARRFALSPIPVYLLAGLSLGNGGILGVAAAGEFIAT 60 +EVSRALLFELGVLLAVLAVLGAVARRFALSPIPVYLLAGLSLGNGGILGVAAAGEFIAT Sbjct 1 MEVSRALLFELGVLLAVLAVLGAVARRFALSPIPVYLLAGLSLGNGGILGVAAAGEFIAT 60 Query 61 GAPIGVVLLLLALGLEFSATEFASSLRHHLPSAGVDIVLNATPGAVAGWLLGLDGVAILG 120 GAPIGVVLLLLALGLEFSATEFASSLRHHLPSAGVDIVLNATPGAVAGWLLGLDGVAILG Sbjct 61 GAPIGVVLLLLALGLEFSATEFASSLRHHLPSAGVDIVLNATPGAVAGWLLGLDGVAILG 120 Query 121 LAGVTYISSSGVIARLLEDLRRLGNRETPAVLSVLVLEDFAMAAYLPLFAVLATDGSWLE 180 LAGVTYISSSGVIARLLEDLRRLGNRETPAVLSVLVLEDFAMAAYLPLFAVLATDGSWLE Sbjct 121 LAGVTYISSSGVIARLLEDLRRLGNRETPAVLSVLVLEDFAMAAYLPLFAVLATDGSWLE 180 Query 181 AVVGMTVAIAALLGAFAASYRWGHHVGRLVTHPDSEQLLLRVLGITLIVAAVAESLHASA 240 AVVGMTVAIAALLGAFAASYRWGHHVGRLVTHPDSEQLLLRVLGITLIVAAVAESLHASA Sbjct 181 AVVGMTVAIAALLGAFAASYRWGHHVGRLVTHPDSEQLLLRVLGITLIVAAVAESLHASA 240 Query 241 AVGAFLVGLTLTGETADRARMVLTPLRDLFATIFFLGIGLSVDPGKLVSMLPVALALAAV 300 AVGAFLVGLTLTGETADRARMVLTPLRDLFATIFFLGIGLSVDPGKLVSMLPVALALAAV Sbjct 241 AVGAFLVGLTLTGETADRARMVLTPLRDLFATIFFLGIGLSVDPGKLVSMLPVALALAAV 300 Query 301 TAATKVATGMFAARREGVARRGQLRAGTALVARGEFSLIIIGLAGASIPGVAALATAYVF 360 TAATKVATGMFAARREGVARRGQLRAGTALVARGEFSLIIIGLAGASIPGVAALATAYVF Sbjct 301 TAATKVATGMFAARREGVARRGQLRAGTALVARGEFSLIIIGLAGASIPGVAALATAYVF 360 Query 361 VMAIVGPILARYTGGGLPAAAVASN 385 VMAIVGPIL RYTGGGLPAAAVASN Sbjct 361 VMAIVGPILTRYTGGGLPAAAVASN 385 >gi|306782286|ref|ZP_07420623.1| conserved membrane transporter [Mycobacterium tuberculosis SUMu002] gi|306786109|ref|ZP_07424431.1| conserved membrane transporter [Mycobacterium tuberculosis SUMu003] gi|306790476|ref|ZP_07428798.1| conserved membrane transporter [Mycobacterium tuberculosis SUMu004] 13 more sequence titles Length=385 Score = 715 bits (1845), Expect = 0.0, Method: Compositional matrix adjust. Identities = 383/385 (99%), Positives = 384/385 (99%), Gaps = 0/385 (0%) Query 1 VEVSRALLFELGVLLAVLAVLGAVARRFALSPIPVYLLAGLSLGNGGILGVAAAGEFIAT 60 +EVSRALLFELGVLLAVLAVLGAVARRFALSPIPVYLLAGLSLGNGGILGVAAAGEFIAT Sbjct 1 MEVSRALLFELGVLLAVLAVLGAVARRFALSPIPVYLLAGLSLGNGGILGVAAAGEFIAT 60 Query 61 GAPIGVVLLLLALGLEFSATEFASSLRHHLPSAGVDIVLNATPGAVAGWLLGLDGVAILG 120 GAPIGVVLLLLALGLEFSATEFASSLRHHLPSAGVDIVLNATPGAVAGWLLGLDGVAILG Sbjct 61 GAPIGVVLLLLALGLEFSATEFASSLRHHLPSAGVDIVLNATPGAVAGWLLGLDGVAILG 120 Query 121 LAGVTYISSSGVIARLLEDLRRLGNRETPAVLSVLVLEDFAMAAYLPLFAVLATDGSWLE 180 LAGVTYISSSGVIARLLEDLRRLGNRETPA LSVLVLEDFAMAAYLPLFAVLATDGSWLE Sbjct 121 LAGVTYISSSGVIARLLEDLRRLGNRETPAALSVLVLEDFAMAAYLPLFAVLATDGSWLE 180 Query 181 AVVGMTVAIAALLGAFAASYRWGHHVGRLVTHPDSEQLLLRVLGITLIVAAVAESLHASA 240 AVVGMTVAIAALLGAFAASYRWGHHVGRLVTHPDSEQLLLRVLGITLIVAAVAESLHASA Sbjct 181 AVVGMTVAIAALLGAFAASYRWGHHVGRLVTHPDSEQLLLRVLGITLIVAAVAESLHASA 240 Query 241 AVGAFLVGLTLTGETADRARMVLTPLRDLFATIFFLGIGLSVDPGKLVSMLPVALALAAV 300 AVGAFLVGLTLTGETADRARMVLTPLRDLFATIFFLGIGLSVDPGKLVSMLPVALALAAV Sbjct 241 AVGAFLVGLTLTGETADRARMVLTPLRDLFATIFFLGIGLSVDPGKLVSMLPVALALAAV 300 Query 301 TAATKVATGMFAARREGVARRGQLRAGTALVARGEFSLIIIGLAGASIPGVAALATAYVF 360 TAATKVATGMFAARREGVARRGQLRAGTALVARGEFSLIIIGLAGASIPGVAALATAYVF Sbjct 301 TAATKVATGMFAARREGVARRGQLRAGTALVARGEFSLIIIGLAGASIPGVAALATAYVF 360 Query 361 VMAIVGPILARYTGGGLPAAAVASN 385 VMAIVGPILARYTGGGLPAAAVASN Sbjct 361 VMAIVGPILARYTGGGLPAAAVASN 385 >gi|340628215|ref|YP_004746667.1| putative integral membrane transport protein [Mycobacterium canettii CIPT 140010059] gi|340006405|emb|CCC45585.1| putative conserved integral membrane transport protein [Mycobacterium canettii CIPT 140010059] Length=385 Score = 714 bits (1844), Expect = 0.0, Method: Compositional matrix adjust. Identities = 383/385 (99%), Positives = 384/385 (99%), Gaps = 0/385 (0%) Query 1 VEVSRALLFELGVLLAVLAVLGAVARRFALSPIPVYLLAGLSLGNGGILGVAAAGEFIAT 60 +EVSRALLFELGVLLAVLAVLGAVARRFALSPIPVYLLAGLSLGNGGILGVAAAGEFIAT Sbjct 1 MEVSRALLFELGVLLAVLAVLGAVARRFALSPIPVYLLAGLSLGNGGILGVAAAGEFIAT 60 Query 61 GAPIGVVLLLLALGLEFSATEFASSLRHHLPSAGVDIVLNATPGAVAGWLLGLDGVAILG 120 GAPIGVVLLLLALGLEFSATEFASSLRHHLPSAGVDIVLNATPGAVAGWLLGLDGVAILG Sbjct 61 GAPIGVVLLLLALGLEFSATEFASSLRHHLPSAGVDIVLNATPGAVAGWLLGLDGVAILG 120 Query 121 LAGVTYISSSGVIARLLEDLRRLGNRETPAVLSVLVLEDFAMAAYLPLFAVLATDGSWLE 180 LAGVTYISSSGVIARLLEDLRRLGNRETPAVLSVLVLEDFAMAAYLPLFAVLATDGSWLE Sbjct 121 LAGVTYISSSGVIARLLEDLRRLGNRETPAVLSVLVLEDFAMAAYLPLFAVLATDGSWLE 180 Query 181 AVVGMTVAIAALLGAFAASYRWGHHVGRLVTHPDSEQLLLRVLGITLIVAAVAESLHASA 240 AVVGM VAIAALLGAFAASYRWGHHVGRLVTHPDSEQLLLRVLGITLIVAAVAESLHASA Sbjct 181 AVVGMAVAIAALLGAFAASYRWGHHVGRLVTHPDSEQLLLRVLGITLIVAAVAESLHASA 240 Query 241 AVGAFLVGLTLTGETADRARMVLTPLRDLFATIFFLGIGLSVDPGKLVSMLPVALALAAV 300 AVGAFLVGLTLTGETADRARMVLTPLRDLFATIFFLGIGLSVDPGKLVSMLPVALALAAV Sbjct 241 AVGAFLVGLTLTGETADRARMVLTPLRDLFATIFFLGIGLSVDPGKLVSMLPVALALAAV 300 Query 301 TAATKVATGMFAARREGVARRGQLRAGTALVARGEFSLIIIGLAGASIPGVAALATAYVF 360 TAATKVATGMFAARREGVARRGQLRAGTALVARGEFSLIIIGLAGASIPGVAALATAYVF Sbjct 301 TAATKVATGMFAARREGVARRGQLRAGTALVARGEFSLIIIGLAGASIPGVAALATAYVF 360 Query 361 VMAIVGPILARYTGGGLPAAAVASN 385 VMAIVGPILARYTGGGLPAAAVASN Sbjct 361 VMAIVGPILARYTGGGLPAAAVASN 385 >gi|289747054|ref|ZP_06506432.1| integral membrane transporter [Mycobacterium tuberculosis 02_1987] gi|294993824|ref|ZP_06799515.1| membrane transporter [Mycobacterium tuberculosis 210] gi|289687582|gb|EFD55070.1| integral membrane transporter [Mycobacterium tuberculosis 02_1987] gi|339296065|gb|AEJ48176.1| integral membrane transport protein [Mycobacterium tuberculosis CCDC5079] gi|339299675|gb|AEJ51785.1| integral membrane transport protein [Mycobacterium tuberculosis CCDC5180] Length=385 Score = 714 bits (1844), Expect = 0.0, Method: Compositional matrix adjust. Identities = 383/385 (99%), Positives = 384/385 (99%), Gaps = 0/385 (0%) Query 1 VEVSRALLFELGVLLAVLAVLGAVARRFALSPIPVYLLAGLSLGNGGILGVAAAGEFIAT 60 +EVSRALLFELGVLLAVLAVLGAVARRFALSPIPVYLLAGLSLGNGGILGVAAAGEFIAT Sbjct 1 MEVSRALLFELGVLLAVLAVLGAVARRFALSPIPVYLLAGLSLGNGGILGVAAAGEFIAT 60 Query 61 GAPIGVVLLLLALGLEFSATEFASSLRHHLPSAGVDIVLNATPGAVAGWLLGLDGVAILG 120 GAPIGVVLLLLALGLEFSATEFASSLRHHLPSAGVDIVLNA PGAVAGWLLGLDGVAILG Sbjct 61 GAPIGVVLLLLALGLEFSATEFASSLRHHLPSAGVDIVLNAAPGAVAGWLLGLDGVAILG 120 Query 121 LAGVTYISSSGVIARLLEDLRRLGNRETPAVLSVLVLEDFAMAAYLPLFAVLATDGSWLE 180 LAGVTYISSSGVIARLLEDLRRLGNRETPAVLSVLVLEDFAMAAYLPLFAVLATDGSWLE Sbjct 121 LAGVTYISSSGVIARLLEDLRRLGNRETPAVLSVLVLEDFAMAAYLPLFAVLATDGSWLE 180 Query 181 AVVGMTVAIAALLGAFAASYRWGHHVGRLVTHPDSEQLLLRVLGITLIVAAVAESLHASA 240 AVVGMTVAIAALLGAFAASYRWGHHVGRLVTHPDSEQLLLRVLGITLIVAAVAESLHASA Sbjct 181 AVVGMTVAIAALLGAFAASYRWGHHVGRLVTHPDSEQLLLRVLGITLIVAAVAESLHASA 240 Query 241 AVGAFLVGLTLTGETADRARMVLTPLRDLFATIFFLGIGLSVDPGKLVSMLPVALALAAV 300 AVGAFLVGLTLTGETADRARMVLTPLRDLFATIFFLGIGLSVDPGKLVSMLPVALALAAV Sbjct 241 AVGAFLVGLTLTGETADRARMVLTPLRDLFATIFFLGIGLSVDPGKLVSMLPVALALAAV 300 Query 301 TAATKVATGMFAARREGVARRGQLRAGTALVARGEFSLIIIGLAGASIPGVAALATAYVF 360 TAATKVATGMFAARREGVARRGQLRAGTALVARGEFSLIIIGLAGASIPGVAALATAYVF Sbjct 301 TAATKVATGMFAARREGVARRGQLRAGTALVARGEFSLIIIGLAGASIPGVAALATAYVF 360 Query 361 VMAIVGPILARYTGGGLPAAAVASN 385 VMAIVGPILARYTGGGLPAAAVASN Sbjct 361 VMAIVGPILARYTGGGLPAAAVASN 385 >gi|339633246|ref|YP_004724888.1| transporter [Mycobacterium africanum GM041182] gi|339332602|emb|CCC28317.1| putative conserved integral membrane transport protein [Mycobacterium africanum GM041182] Length=385 Score = 714 bits (1844), Expect = 0.0, Method: Compositional matrix adjust. Identities = 383/385 (99%), Positives = 384/385 (99%), Gaps = 0/385 (0%) Query 1 VEVSRALLFELGVLLAVLAVLGAVARRFALSPIPVYLLAGLSLGNGGILGVAAAGEFIAT 60 +EVSRALLFELGVLLAVLAVLGAVARRFALSPIPVYLLAGLSLGNGGILGVAAAGEFIAT Sbjct 1 MEVSRALLFELGVLLAVLAVLGAVARRFALSPIPVYLLAGLSLGNGGILGVAAAGEFIAT 60 Query 61 GAPIGVVLLLLALGLEFSATEFASSLRHHLPSAGVDIVLNATPGAVAGWLLGLDGVAILG 120 GAPIGVVLLLLALGLEFSATEFASSLRHHLPSAGVDIVLNATPGAVAGWLLGLDGVAILG Sbjct 61 GAPIGVVLLLLALGLEFSATEFASSLRHHLPSAGVDIVLNATPGAVAGWLLGLDGVAILG 120 Query 121 LAGVTYISSSGVIARLLEDLRRLGNRETPAVLSVLVLEDFAMAAYLPLFAVLATDGSWLE 180 LAGVTYISSSGVIARLLEDLRRLGNRETPAVLSVLVLEDFAMAAYLPLFAVLATDGSWLE Sbjct 121 LAGVTYISSSGVIARLLEDLRRLGNRETPAVLSVLVLEDFAMAAYLPLFAVLATDGSWLE 180 Query 181 AVVGMTVAIAALLGAFAASYRWGHHVGRLVTHPDSEQLLLRVLGITLIVAAVAESLHASA 240 AVVGMTVAIAALLGAFAASYRWGHHVGRLVTHPDSEQLLLRVLGITLIVAAVAESLHASA Sbjct 181 AVVGMTVAIAALLGAFAASYRWGHHVGRLVTHPDSEQLLLRVLGITLIVAAVAESLHASA 240 Query 241 AVGAFLVGLTLTGETADRARMVLTPLRDLFATIFFLGIGLSVDPGKLVSMLPVALALAAV 300 AVGAFLVGLTLTGETADRARMVLTPLRDLFATIFFLGIGLSVDPGKLVSMLPVALALAAV Sbjct 241 AVGAFLVGLTLTGETADRARMVLTPLRDLFATIFFLGIGLSVDPGKLVSMLPVALALAAV 300 Query 301 TAATKVATGMFAARREGVARRGQLRAGTALVARGEFSLIIIGLAGASIPGVAALATAYVF 360 TAATKVATGMFAARREGVARRGQL AGTALVARGEFSLIIIGLAGASIPGVAALATAYVF Sbjct 301 TAATKVATGMFAARREGVARRGQLHAGTALVARGEFSLIIIGLAGASIPGVAALATAYVF 360 Query 361 VMAIVGPILARYTGGGLPAAAVASN 385 VMAIVGPILARYTGGGLPAAAVASN Sbjct 361 VMAIVGPILARYTGGGLPAAAVASN 385 >gi|167967987|ref|ZP_02550264.1| conserved integral membrane transport protein [Mycobacterium tuberculosis H37Ra] Length=378 Score = 704 bits (1818), Expect = 0.0, Method: Compositional matrix adjust. Identities = 377/378 (99%), Positives = 378/378 (100%), Gaps = 0/378 (0%) Query 8 LFELGVLLAVLAVLGAVARRFALSPIPVYLLAGLSLGNGGILGVAAAGEFIATGAPIGVV 67 +FELGVLLAVLAVLGAVARRFALSPIPVYLLAGLSLGNGGILGVAAAGEFIATGAPIGVV Sbjct 1 MFELGVLLAVLAVLGAVARRFALSPIPVYLLAGLSLGNGGILGVAAAGEFIATGAPIGVV 60 Query 68 LLLLALGLEFSATEFASSLRHHLPSAGVDIVLNATPGAVAGWLLGLDGVAILGLAGVTYI 127 LLLLALGLEFSATEFASSLRHHLPSAGVDIVLNATPGAVAGWLLGLDGVAILGLAGVTYI Sbjct 61 LLLLALGLEFSATEFASSLRHHLPSAGVDIVLNATPGAVAGWLLGLDGVAILGLAGVTYI 120 Query 128 SSSGVIARLLEDLRRLGNRETPAVLSVLVLEDFAMAAYLPLFAVLATDGSWLEAVVGMTV 187 SSSGVIARLLEDLRRLGNRETPAVLSVLVLEDFAMAAYLPLFAVLATDGSWLEAVVGMTV Sbjct 121 SSSGVIARLLEDLRRLGNRETPAVLSVLVLEDFAMAAYLPLFAVLATDGSWLEAVVGMTV 180 Query 188 AIAALLGAFAASYRWGHHVGRLVTHPDSEQLLLRVLGITLIVAAVAESLHASAAVGAFLV 247 AIAALLGAFAASYRWGHHVGRLVTHPDSEQLLLRVLGITLIVAAVAESLHASAAVGAFLV Sbjct 181 AIAALLGAFAASYRWGHHVGRLVTHPDSEQLLLRVLGITLIVAAVAESLHASAAVGAFLV 240 Query 248 GLTLTGETADRARMVLTPLRDLFATIFFLGIGLSVDPGKLVSMLPVALALAAVTAATKVA 307 GLTLTGETADRARMVLTPLRDLFATIFFLGIGLSVDPGKLVSMLPVALALAAVTAATKVA Sbjct 241 GLTLTGETADRARMVLTPLRDLFATIFFLGIGLSVDPGKLVSMLPVALALAAVTAATKVA 300 Query 308 TGMFAARREGVARRGQLRAGTALVARGEFSLIIIGLAGASIPGVAALATAYVFVMAIVGP 367 TGMFAARREGVARRGQLRAGTALVARGEFSLIIIGLAGASIPGVAALATAYVFVMAIVGP Sbjct 301 TGMFAARREGVARRGQLRAGTALVARGEFSLIIIGLAGASIPGVAALATAYVFVMAIVGP 360 Query 368 ILARYTGGGLPAAAVASN 385 ILARYTGGGLPAAAVASN Sbjct 361 ILARYTGGGLPAAAVASN 378 >gi|15827342|ref|NP_301605.1| transmembrane transport protein [Mycobacterium leprae TN] gi|221229820|ref|YP_002503236.1| putative transmembrane transport protein [Mycobacterium leprae Br4923] gi|13092891|emb|CAC30291.1| putative transmembrane transport protein [Mycobacterium leprae] gi|219932927|emb|CAR70876.1| putative transmembrane transport protein [Mycobacterium leprae Br4923] Length=385 Score = 582 bits (1501), Expect = 3e-164, Method: Compositional matrix adjust. Identities = 314/385 (82%), Positives = 341/385 (89%), Gaps = 0/385 (0%) Query 1 VEVSRALLFELGVLLAVLAVLGAVARRFALSPIPVYLLAGLSLGNGGILGVAAAGEFIAT 60 +E+S ALL ++G LL LAVLGA ARR++LSPIPVYL+AGLSLG GGI+ V+AA EFI T Sbjct 1 MEISGALLSQVGALLTTLAVLGAGARRYSLSPIPVYLMAGLSLGKGGIMPVSAADEFITT 60 Query 61 GAPIGVVLLLLALGLEFSATEFASSLRHHLPSAGVDIVLNATPGAVAGWLLGLDGVAILG 120 GAPIG+VLLLL LGLEFSATEFASSLR HLPSAGVDI+LNATPGAVAGWLLGLDGVA+L Sbjct 61 GAPIGIVLLLLTLGLEFSATEFASSLRRHLPSAGVDIILNATPGAVAGWLLGLDGVAVLA 120 Query 121 LAGVTYISSSGVIARLLEDLRRLGNRETPAVLSVLVLEDFAMAAYLPLFAVLATDGSWLE 180 LAGVTYISSSGVIARLL DLRRLGNRETPAVLSVLVLEDFAMAAYLPLFAVLA GSWL+ Sbjct 121 LAGVTYISSSGVIARLLADLRRLGNRETPAVLSVLVLEDFAMAAYLPLFAVLAAGGSWLD 180 Query 181 AVVGMTVAIAALLGAFAASYRWGHHVGRLVTHPDSEQLLLRVLGITLIVAAVAESLHASA 240 AVVGM VA+ AL AFAASY WGHHVGRLV HPDSEQLLLRVLG+TLIVAAVAESLHASA Sbjct 181 AVVGMIVAVCALFAAFAASYHWGHHVGRLVAHPDSEQLLLRVLGVTLIVAAVAESLHASA 240 Query 241 AVGAFLVGLTLTGETADRARMVLTPLRDLFATIFFLGIGLSVDPGKLVSMLPVALALAAV 300 AVGAFLVGLTLTG+TA+RAR VL PLRDLFA IFFL IG+SVDP KL+ M P AL LA V Sbjct 241 AVGAFLVGLTLTGDTAERARKVLGPLRDLFAAIFFLAIGISVDPHKLLPMFPTALILATV 300 Query 301 TAATKVATGMFAARREGVARRGQLRAGTALVARGEFSLIIIGLAGASIPGVAALATAYVF 360 TA TKVATG+ AAR +GVARRGQLRAGTALVARGEFSLIIIGL G S P VAALATAYVF Sbjct 301 TAVTKVATGILAARYDGVARRGQLRAGTALVARGEFSLIIIGLVGTSTPAVAALATAYVF 360 Query 361 VMAIVGPILARYTGGGLPAAAVASN 385 +MAI GP+LARYT G LP ++ ++N Sbjct 361 IMAIAGPVLARYTPGSLPTSSGSAN 385 >gi|240170361|ref|ZP_04749020.1| membrane transporter [Mycobacterium kansasii ATCC 12478] Length=381 Score = 553 bits (1425), Expect = 2e-155, Method: Compositional matrix adjust. Identities = 321/379 (85%), Positives = 345/379 (92%), Gaps = 0/379 (0%) Query 3 VSRALLFELGVLLAVLAVLGAVARRFALSPIPVYLLAGLSLGNGGILGVAAAGEFIATGA 62 VS ALLFELG LL +LA+LGA+ARRFALSPIPVYLLAGL+LG GGIL VAAA +F++TGA Sbjct 3 VSEALLFELGALLVMLALLGALARRFALSPIPVYLLAGLALGKGGILPVAAAADFVSTGA 62 Query 63 PIGVVLLLLALGLEFSATEFASSLRHHLPSAGVDIVLNATPGAVAGWLLGLDGVAILGLA 122 PIG+VLLLL LGLEFSATEFASSLRHHLPSAGVDIVLNATPGAV GWLLGLDGVAI+ LA Sbjct 63 PIGIVLLLLTLGLEFSATEFASSLRHHLPSAGVDIVLNATPGAVTGWLLGLDGVAIVALA 122 Query 123 GVTYISSSGVIARLLEDLRRLGNRETPAVLSVLVLEDFAMAAYLPLFAVLATDGSWLEAV 182 GVTYISSSGVIARLLEDLRRLGNRETPAVLSVLVLEDFAMAAYLP+F VLA GSWL+A+ Sbjct 123 GVTYISSSGVIARLLEDLRRLGNRETPAVLSVLVLEDFAMAAYLPMFTVLALRGSWLDAL 182 Query 183 VGMTVAIAALLGAFAASYRWGHHVGRLVTHPDSEQLLLRVLGITLIVAAVAESLHASAAV 242 G AI ALL AFAASY WGHHVGRLV HPDSEQLLLRVLGITL+VAA+AESLHASAAV Sbjct 183 GGTLAAIGALLAAFAASYYWGHHVGRLVAHPDSEQLLLRVLGITLLVAALAESLHASAAV 242 Query 243 GAFLVGLTLTGETADRARMVLTPLRDLFATIFFLGIGLSVDPGKLVSMLPVALALAAVTA 302 GAFLVGLTLTGETADRAR VL PLRDLFA IFFL IGLSV P +L+ MLPVA+ LAAVTA Sbjct 243 GAFLVGLTLTGETADRARKVLGPLRDLFAAIFFLAIGLSVSPKELLPMLPVAVVLAAVTA 302 Query 303 ATKVATGMFAARREGVARRGQLRAGTALVARGEFSLIIIGLAGASIPGVAALATAYVFVM 362 ATKV TGM+AARR+GVARRGQLRAGTAL+ARGEFSLIIIGL G SIP VAALAT+YVF+M Sbjct 303 ATKVLTGMYAARRDGVARRGQLRAGTALIARGEFSLIIIGLVGVSIPTVAALATSYVFIM 362 Query 363 AIVGPILARYTGGGLPAAA 381 AIVGP++ARYTGG L AAA Sbjct 363 AIVGPVVARYTGGPLRAAA 381 >gi|183981331|ref|YP_001849622.1| membrane transporter [Mycobacterium marinum M] gi|183174657|gb|ACC39767.1| conserved membrane transport protein [Mycobacterium marinum M] Length=381 Score = 546 bits (1406), Expect = 3e-153, Method: Compositional matrix adjust. Identities = 315/375 (84%), Positives = 339/375 (91%), Gaps = 0/375 (0%) Query 1 VEVSRALLFELGVLLAVLAVLGAVARRFALSPIPVYLLAGLSLGNGGILGVAAAGEFIAT 60 +EVSRALLFE+G LL LA+LGA+ARRFALSPIPVYLLAGLSLG GG+L VAAA +F+AT Sbjct 1 MEVSRALLFEVGALLTTLALLGAIARRFALSPIPVYLLAGLSLGKGGVLPVAAADDFVAT 60 Query 61 GAPIGVVLLLLALGLEFSATEFASSLRHHLPSAGVDIVLNATPGAVAGWLLGLDGVAILG 120 GAPIG+VLLLL LGLEFSATEFASSLRHH+PSA VDIVLNATPGAVAGWLLGLDGVAIL Sbjct 61 GAPIGIVLLLLTLGLEFSATEFASSLRHHMPSAMVDIVLNATPGAVAGWLLGLDGVAILA 120 Query 121 LAGVTYISSSGVIARLLEDLRRLGNRETPAVLSVLVLEDFAMAAYLPLFAVLATDGSWLE 180 LAGVTYISSSGV+ARLLEDLRRLGNRETPAVLSVLVLEDFAMA YLPLF VLA G WL Sbjct 121 LAGVTYISSSGVVARLLEDLRRLGNRETPAVLSVLVLEDFAMAGYLPLFTVLALHGDWLH 180 Query 181 AVVGMTVAIAALLGAFAASYRWGHHVGRLVTHPDSEQLLLRVLGITLIVAAVAESLHASA 240 A+ G AIAALLGAFAAS+ WGHH GRL HPDSEQLLLRVLGITL+VAA+AE+LHASA Sbjct 181 ALGGTLAAIAALLGAFAASFYWGHHFGRLFAHPDSEQLLLRVLGITLMVAALAETLHASA 240 Query 241 AVGAFLVGLTLTGETADRARMVLTPLRDLFATIFFLGIGLSVDPGKLVSMLPVALALAAV 300 AVGAFLVGLTLTGETA+RAR VL PLRDLFA IFFLGIGLSV P +L+ LPVA+ LA V Sbjct 241 AVGAFLVGLTLTGETAERARRVLGPLRDLFAAIFFLGIGLSVAPKELIPALPVAMVLAVV 300 Query 301 TAATKVATGMFAARREGVARRGQLRAGTALVARGEFSLIIIGLAGASIPGVAALATAYVF 360 TAATKV TGMFAARR+GVARRGQLRAGTAL+ARGEFSLIIIGL GASIP VAALATAYVF Sbjct 301 TAATKVLTGMFAARRDGVARRGQLRAGTALIARGEFSLIIIGLVGASIPAVAALATAYVF 360 Query 361 VMAIVGPILARYTGG 375 +MA+ GP+LARYTGG Sbjct 361 IMAVAGPVLARYTGG 375 >gi|118618050|ref|YP_906382.1| membrane transporter [Mycobacterium ulcerans Agy99] gi|118570160|gb|ABL04911.1| conserved membrane transport protein [Mycobacterium ulcerans Agy99] Length=381 Score = 545 bits (1404), Expect = 5e-153, Method: Compositional matrix adjust. Identities = 315/375 (84%), Positives = 339/375 (91%), Gaps = 0/375 (0%) Query 1 VEVSRALLFELGVLLAVLAVLGAVARRFALSPIPVYLLAGLSLGNGGILGVAAAGEFIAT 60 +EVSRALLFE+G LL LA+LGA+ARRFALSPIPVYLLAGLSLG GG+L VAAA +F+AT Sbjct 1 MEVSRALLFEVGALLTTLALLGAIARRFALSPIPVYLLAGLSLGKGGVLPVAAADDFVAT 60 Query 61 GAPIGVVLLLLALGLEFSATEFASSLRHHLPSAGVDIVLNATPGAVAGWLLGLDGVAILG 120 GAPIG+VLLLL LGLEFSATEFASSLRHH+PSA VDIVLNATPGAVAGWLLGLDGVAIL Sbjct 61 GAPIGIVLLLLTLGLEFSATEFASSLRHHMPSAMVDIVLNATPGAVAGWLLGLDGVAILA 120 Query 121 LAGVTYISSSGVIARLLEDLRRLGNRETPAVLSVLVLEDFAMAAYLPLFAVLATDGSWLE 180 LAGVTYISSSGV+ARLLEDLRRLGNRETPAVLSVLVLEDFAMA YLPLF VLA G WL Sbjct 121 LAGVTYISSSGVVARLLEDLRRLGNRETPAVLSVLVLEDFAMAGYLPLFTVLALHGDWLH 180 Query 181 AVVGMTVAIAALLGAFAASYRWGHHVGRLVTHPDSEQLLLRVLGITLIVAAVAESLHASA 240 A+ G AIAALLGAFAAS+ WGHH GRL HPDSEQLLLRVLGITL+VAA+AE+LHASA Sbjct 181 ALGGTLAAIAALLGAFAASFYWGHHFGRLFAHPDSEQLLLRVLGITLMVAALAETLHASA 240 Query 241 AVGAFLVGLTLTGETADRARMVLTPLRDLFATIFFLGIGLSVDPGKLVSMLPVALALAAV 300 AVGAFLVGLTLTGETA+RAR VL PLRDLFA IFFLGIGLSV P +L+ LPVA+ LA V Sbjct 241 AVGAFLVGLTLTGETAERARRVLGPLRDLFAAIFFLGIGLSVAPKELIPALPVAILLAVV 300 Query 301 TAATKVATGMFAARREGVARRGQLRAGTALVARGEFSLIIIGLAGASIPGVAALATAYVF 360 TAATKV TGMFAARR+GVARRGQLRAGTAL+ARGEFSLIIIGL GASIP VAALATAYVF Sbjct 301 TAATKVLTGMFAARRDGVARRGQLRAGTALIARGEFSLIIIGLVGASIPAVAALATAYVF 360 Query 361 VMAIVGPILARYTGG 375 +MA+ GP+LARYTGG Sbjct 361 IMAVAGPVLARYTGG 375 >gi|296168974|ref|ZP_06850641.1| sodium/hydrogen exchanger [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295896360|gb|EFG76015.1| sodium/hydrogen exchanger [Mycobacterium parascrofulaceum ATCC BAA-614] Length=385 Score = 534 bits (1376), Expect = 8e-150, Method: Compositional matrix adjust. Identities = 307/358 (86%), Positives = 327/358 (92%), Gaps = 0/358 (0%) Query 20 VLGAVARRFALSPIPVYLLAGLSLGNGGILGVAAAGEFIATGAPIGVVLLLLALGLEFSA 79 ++G +ARRFALSPIPVYLLAGLSLG GGIL VAAAG+F+ T AP+GVVLLLL LGLEFS Sbjct 20 IVGGLARRFALSPIPVYLLAGLSLGKGGILPVAAAGDFVTTSAPLGVVLLLLTLGLEFSV 79 Query 80 TEFASSLRHHLPSAGVDIVLNATPGAVAGWLLGLDGVAILGLAGVTYISSSGVIARLLED 139 EFASS+RHHLPSAGVD+VLNA PGAVAGWLLGLDGVAIL LAGVTYISSSGV+ARLLED Sbjct 80 AEFASSMRHHLPSAGVDVVLNAAPGAVAGWLLGLDGVAILCLAGVTYISSSGVVARLLED 139 Query 140 LRRLGNRETPAVLSVLVLEDFAMAAYLPLFAVLATDGSWLEAVVGMTVAIAALLGAFAAS 199 LRR+GNRETP+VLSVLVLEDFAMAAYLP FAVLA G WL AVVGM VAI AL+ AFAAS Sbjct 140 LRRIGNRETPSVLSVLVLEDFAMAAYLPPFAVLAAGGGWLRAVVGMAVAIGALVAAFAAS 199 Query 200 YRWGHHVGRLVTHPDSEQLLLRVLGITLIVAAVAESLHASAAVGAFLVGLTLTGETADRA 259 YRWGHH GRLV HPDSEQLLLRVLGITLIVAA+AESLHASAAVGAFLVGLTLTGETADRA Sbjct 200 YRWGHHFGRLVEHPDSEQLLLRVLGITLIVAAMAESLHASAAVGAFLVGLTLTGETADRA 259 Query 260 RMVLTPLRDLFATIFFLGIGLSVDPGKLVSMLPVALALAAVTAATKVATGMFAARREGVA 319 R VL PLRDLFA IFFL IG +VDP +LV MLPVALALAAVTAATKVATGMFAARR+GVA Sbjct 260 RKVLGPLRDLFAAIFFLAIGWAVDPQELVPMLPVALALAAVTAATKVATGMFAARRDGVA 319 Query 320 RRGQLRAGTALVARGEFSLIIIGLAGASIPGVAALATAYVFVMAIVGPILARYTGGGL 377 RRGQLRAGTAL+ARGEFSLIIIGLAG SIP VAALAT+YVF+MAI GP+LARYTGG L Sbjct 320 RRGQLRAGTALIARGEFSLIIIGLAGTSIPAVAALATSYVFIMAIAGPVLARYTGGPL 377 >gi|342861436|ref|ZP_08718083.1| transporter, monovalent cation:proton antiporter-2 (CPA2) family protein [Mycobacterium colombiense CECT 3035] gi|342130925|gb|EGT84214.1| transporter, monovalent cation:proton antiporter-2 (CPA2) family protein [Mycobacterium colombiense CECT 3035] Length=385 Score = 513 bits (1321), Expect = 2e-143, Method: Compositional matrix adjust. Identities = 291/348 (84%), Positives = 314/348 (91%), Gaps = 0/348 (0%) Query 26 RRFALSPIPVYLLAGLSLGNGGILGVAAAGEFIATGAPIGVVLLLLALGLEFSATEFASS 85 RRFALSPIPVYLLAGL+LGNGGIL VAA G+FI T APIGVVLLLL LG EFS EF+SS Sbjct 26 RRFALSPIPVYLLAGLALGNGGILPVAAGGQFITTSAPIGVVLLLLTLGCEFSVAEFSSS 85 Query 86 LRHHLPSAGVDIVLNATPGAVAGWLLGLDGVAILGLAGVTYISSSGVIARLLEDLRRLGN 145 +RHHLPSA VDIVLNA PGA+AG LLGLDGVA+L LAGVTYISSSGVIARLLEDL+RLGN Sbjct 86 MRHHLPSAAVDIVLNAAPGAIAGLLLGLDGVAVLCLAGVTYISSSGVIARLLEDLQRLGN 145 Query 146 RETPAVLSVLVLEDFAMAAYLPLFAVLATDGSWLEAVVGMTVAIAALLGAFAASYRWGHH 205 RETPAVLSVLVLEDFAMAAYLPLFAVLA+ G WL A+ GM VA+ AL+ AFAASYRWGHH Sbjct 146 RETPAVLSVLVLEDFAMAAYLPLFAVLASGGGWLHAIGGMAVAVGALVAAFAASYRWGHH 205 Query 206 VGRLVTHPDSEQLLLRVLGITLIVAAVAESLHASAAVGAFLVGLTLTGETADRARMVLTP 265 V RLV HPDSEQL+LRV+GITLIVAA+AESLHASAAVGAFLVGLTLTGETA+RAR VL+P Sbjct 206 VERLVQHPDSEQLMLRVMGITLIVAAMAESLHASAAVGAFLVGLTLTGETAERARQVLSP 265 Query 266 LRDLFATIFFLGIGLSVDPGKLVSMLPVALALAAVTAATKVATGMFAARREGVARRGQLR 325 LRDLFA IFFL IG SVDP +LV MLP AL LAAVTAATKVATG+FAAR +GVARRGQLR Sbjct 266 LRDLFAAIFFLAIGYSVDPHELVPMLPAALILAAVTAATKVATGIFAARHDGVARRGQLR 325 Query 326 AGTALVARGEFSLIIIGLAGASIPGVAALATAYVFVMAIVGPILARYT 373 AGTAL+ARGEFSLIIIGLAG S+P VAALAT+YVF+MAI GPIL RYT Sbjct 326 AGTALIARGEFSLIIIGLAGKSLPAVAALATSYVFIMAIAGPILTRYT 373 >gi|108799828|ref|YP_640025.1| sodium/hydrogen exchanger [Mycobacterium sp. MCS] gi|119868938|ref|YP_938890.1| sodium/hydrogen exchanger [Mycobacterium sp. KMS] gi|108770247|gb|ABG08969.1| potassium/proton antiporter membrane subunit, CPA2 family [Mycobacterium sp. MCS] gi|119695027|gb|ABL92100.1| potassium/proton antiporter membrane subunit, CPA2 family [Mycobacterium sp. KMS] Length=384 Score = 491 bits (1265), Expect = 7e-137, Method: Compositional matrix adjust. Identities = 287/379 (76%), Positives = 329/379 (87%), Gaps = 0/379 (0%) Query 1 VEVSRALLFELGVLLAVLAVLGAVARRFALSPIPVYLLAGLSLGNGGILGVAAAGEFIAT 60 +EVS LL ELGV+LA L VLG +ARRFALSPIP+YLLAGL++G GG+ V AAG+F+ T Sbjct 1 MEVSATLLLELGVILAALTVLGTIARRFALSPIPLYLLAGLAVGEGGLAPVPAAGDFVET 60 Query 61 GAPIGVVLLLLALGLEFSATEFASSLRHHLPSAGVDIVLNATPGAVAGWLLGLDGVAILG 120 GA IGVVLLLL LGLEFS EFA+SLR HLPSAGVD+VLNA PGA+AGWL+GLDGV IL Sbjct 61 GATIGVVLLLLTLGLEFSIGEFATSLRRHLPSAGVDLVLNAAPGAIAGWLIGLDGVGILA 120 Query 121 LAGVTYISSSGVIARLLEDLRRLGNRETPAVLSVLVLEDFAMAAYLPLFAVLATDGSWLE 180 LAGVT+ISSSGVIARLL DLRRLGNRETPAVLS+LVLEDFAMAAYLPL AVLAT G++L+ Sbjct 121 LAGVTWISSSGVIARLLSDLRRLGNRETPAVLSILVLEDFAMAAYLPLLAVLATGGTFLQ 180 Query 181 AVVGMTVAIAALLGAFAASYRWGHHVGRLVTHPDSEQLLLRVLGITLIVAAVAESLHASA 240 A++GM +A++AL AF SYRWGHHVGRLV HPD+EQLLLR+LG+TLIVAA+AE +HASA Sbjct 181 ALLGMAIAVSALGFAFVVSYRWGHHVGRLVVHPDNEQLLLRILGLTLIVAALAEFIHASA 240 Query 241 AVGAFLVGLTLTGETADRARMVLTPLRDLFATIFFLGIGLSVDPGKLVSMLPVALALAAV 300 AVGAFLVGLTLTGE A+RAR VLTPLRDLFA IFFL IG+SVDP L+ MLPVA ALA Sbjct 241 AVGAFLVGLTLTGEAAERARTVLTPLRDLFAAIFFLAIGVSVDPAALIPMLPVATALAVA 300 Query 301 TAATKVATGMFAARREGVARRGQLRAGTALVARGEFSLIIIGLAGASIPGVAALATAYVF 360 TAATKV TG FAARR+GV R GQLRAGTAL+ARGEFSL+IIGL GAS+ + A+AT YVF Sbjct 301 TAATKVLTGQFAARRDGVGRPGQLRAGTALIARGEFSLVIIGLVGASVEALEAVATPYVF 360 Query 361 VMAIVGPILARYTGGGLPA 379 ++A+VGP+LAR+TGG PA Sbjct 361 ILAMVGPVLARFTGGRAPA 379 >gi|126435471|ref|YP_001071162.1| sodium/hydrogen exchanger [Mycobacterium sp. JLS] gi|126235271|gb|ABN98671.1| potassium/proton antiporter membrane subunit, CPA2 family [Mycobacterium sp. JLS] Length=384 Score = 489 bits (1258), Expect = 4e-136, Method: Compositional matrix adjust. Identities = 286/379 (76%), Positives = 328/379 (87%), Gaps = 0/379 (0%) Query 1 VEVSRALLFELGVLLAVLAVLGAVARRFALSPIPVYLLAGLSLGNGGILGVAAAGEFIAT 60 +EVS LL ELGV+LA L VLG +ARRFALSPIP+YLLAGL++G GG+ V AAG+F+ T Sbjct 1 MEVSATLLLELGVILAALTVLGTIARRFALSPIPLYLLAGLAVGEGGLAPVPAAGDFVET 60 Query 61 GAPIGVVLLLLALGLEFSATEFASSLRHHLPSAGVDIVLNATPGAVAGWLLGLDGVAILG 120 GA IGVVLLLL LGLEFS EFA+SLR HLPSAGVD+VLNA PGA+AGWL+GLDGV IL Sbjct 61 GATIGVVLLLLTLGLEFSIGEFATSLRRHLPSAGVDLVLNAAPGAIAGWLIGLDGVGILA 120 Query 121 LAGVTYISSSGVIARLLEDLRRLGNRETPAVLSVLVLEDFAMAAYLPLFAVLATDGSWLE 180 LAGVT+ISSSGVIARLL DLRRLGNRETPAVLS+LVLEDFAMAAYLPL AVLAT G++L+ Sbjct 121 LAGVTWISSSGVIARLLSDLRRLGNRETPAVLSILVLEDFAMAAYLPLLAVLATGGTFLQ 180 Query 181 AVVGMTVAIAALLGAFAASYRWGHHVGRLVTHPDSEQLLLRVLGITLIVAAVAESLHASA 240 A++GM +A++AL AF SYRWGHHVGRLV HPD+EQLLLR+LG+TLIVAA+AE +HASA Sbjct 181 ALLGMAIAVSALGFAFVVSYRWGHHVGRLVVHPDNEQLLLRILGLTLIVAALAEFIHASA 240 Query 241 AVGAFLVGLTLTGETADRARMVLTPLRDLFATIFFLGIGLSVDPGKLVSMLPVALALAAV 300 AVGAFLVGLTLTGE A+RAR VLTPLRDLFA IFFL IG+SVDP L+ MLPVA ALA Sbjct 241 AVGAFLVGLTLTGEAAERARTVLTPLRDLFAAIFFLAIGVSVDPAALIPMLPVATALAVA 300 Query 301 TAATKVATGMFAARREGVARRGQLRAGTALVARGEFSLIIIGLAGASIPGVAALATAYVF 360 TAATKV TG FAARR+GV R GQLRAGTAL+ARGEFSL+IIGL GAS+ + A+AT YV Sbjct 301 TAATKVLTGQFAARRDGVGRPGQLRAGTALIARGEFSLVIIGLVGASVEALEAVATPYVL 360 Query 361 VMAIVGPILARYTGGGLPA 379 ++A+VGP+LAR+TGG PA Sbjct 361 ILAMVGPVLARFTGGRAPA 379 >gi|118463113|ref|YP_883343.1| transporter, monovalent cation:proton antiporter-2 (CPA2) family protein [Mycobacterium avium 104] gi|254776635|ref|ZP_05218151.1| transporter, monovalent cation:proton antiporter-2 (CPA2) family protein [Mycobacterium avium subsp. avium ATCC 25291] gi|118164400|gb|ABK65297.1| transporter, monovalent cation:proton antiporter-2 (CPA2) family protein [Mycobacterium avium 104] Length=382 Score = 481 bits (1237), Expect = 1e-133, Method: Compositional matrix adjust. Identities = 289/349 (83%), Positives = 314/349 (90%), Gaps = 0/349 (0%) Query 26 RRFALSPIPVYLLAGLSLGNGGILGVAAAGEFIATGAPIGVVLLLLALGLEFSATEFASS 85 RRFALSPIPVYLLAGL+LG GG+L +A G+FI T APIGVVLLLL LG EFS EF+SS Sbjct 26 RRFALSPIPVYLLAGLALGKGGLLPLATGGQFITTSAPIGVVLLLLTLGCEFSVAEFSSS 85 Query 86 LRHHLPSAGVDIVLNATPGAVAGWLLGLDGVAILGLAGVTYISSSGVIARLLEDLRRLGN 145 +RHHLPSA VD+VLNA PGA+AGWLLGLDGVAIL LAGVTYISSSGV+ARLLEDLRRLGN Sbjct 86 MRHHLPSAAVDVVLNAAPGAIAGWLLGLDGVAILCLAGVTYISSSGVVARLLEDLRRLGN 145 Query 146 RETPAVLSVLVLEDFAMAAYLPLFAVLATDGSWLEAVVGMTVAIAALLGAFAASYRWGHH 205 RETPAVLSVLVLEDFAMAAYLPLFAVLA+ G WL AVVGM VA++AL+ AFAASYRWGHH Sbjct 146 RETPAVLSVLVLEDFAMAAYLPLFAVLASGGGWLHAVVGMVVAVSALVAAFAASYRWGHH 205 Query 206 VGRLVTHPDSEQLLLRVLGITLIVAAVAESLHASAAVGAFLVGLTLTGETADRARMVLTP 265 V RLV HPDSEQL+LRVLGITLIVAA+AESLHASAAVGAFLVGLTLTGETA R R VL P Sbjct 206 VQRLVEHPDSEQLMLRVLGITLIVAAMAESLHASAAVGAFLVGLTLTGETATRTRQVLAP 265 Query 266 LRDLFATIFFLGIGLSVDPGKLVSMLPVALALAAVTAATKVATGMFAARREGVARRGQLR 325 LRDLFA IFFL IG SVDP +L+ MLP AL LAA TAATKVATG+FAAR +GVARRGQLR Sbjct 266 LRDLFAAIFFLAIGYSVDPHELIPMLPAALILAAATAATKVATGIFAARHDGVARRGQLR 325 Query 326 AGTALVARGEFSLIIIGLAGASIPGVAALATAYVFVMAIVGPILARYTG 374 AGTAL+ARGEFSLIIIGLAG+S+P VAALAT+YVF+MAI GP+LARYTG Sbjct 326 AGTALIARGEFSLIIIGLAGSSLPAVAALATSYVFIMAIAGPVLARYTG 374 >gi|41409447|ref|NP_962283.1| hypothetical protein MAP3349c [Mycobacterium avium subsp. paratuberculosis K-10] gi|41398278|gb|AAS05899.1| KefB [Mycobacterium avium subsp. paratuberculosis K-10] gi|336459556|gb|EGO38492.1| Kef-type K+ transport system, membrane component [Mycobacterium avium subsp. paratuberculosis S397] Length=382 Score = 478 bits (1229), Expect = 1e-132, Method: Compositional matrix adjust. Identities = 288/349 (83%), Positives = 313/349 (90%), Gaps = 0/349 (0%) Query 26 RRFALSPIPVYLLAGLSLGNGGILGVAAAGEFIATGAPIGVVLLLLALGLEFSATEFASS 85 RRFALSPIPVYLLAGL+LG GG+L +A G+FI T APIGVVLLLL LG EFS EF+SS Sbjct 26 RRFALSPIPVYLLAGLALGKGGLLPLATGGQFITTSAPIGVVLLLLTLGCEFSLAEFSSS 85 Query 86 LRHHLPSAGVDIVLNATPGAVAGWLLGLDGVAILGLAGVTYISSSGVIARLLEDLRRLGN 145 +RHHLPSA VD+VLNA PGA+AGWLLGLDGVAIL LAGVTYISSSGV+ARLLEDL RLGN Sbjct 86 MRHHLPSAAVDVVLNAAPGAIAGWLLGLDGVAILCLAGVTYISSSGVVARLLEDLHRLGN 145 Query 146 RETPAVLSVLVLEDFAMAAYLPLFAVLATDGSWLEAVVGMTVAIAALLGAFAASYRWGHH 205 RETPAVLSVLVLEDFAMAAYLPLFAVLA+ G WL AVVGM VA++AL+ AFAASYRWGHH Sbjct 146 RETPAVLSVLVLEDFAMAAYLPLFAVLASGGGWLHAVVGMVVAVSALVAAFAASYRWGHH 205 Query 206 VGRLVTHPDSEQLLLRVLGITLIVAAVAESLHASAAVGAFLVGLTLTGETADRARMVLTP 265 V RLV HPDSEQL+LRVLGITLIVAA+AESLHASAAVGAFLVGLTLTGETA R R VL P Sbjct 206 VQRLVEHPDSEQLMLRVLGITLIVAAMAESLHASAAVGAFLVGLTLTGETATRTRQVLAP 265 Query 266 LRDLFATIFFLGIGLSVDPGKLVSMLPVALALAAVTAATKVATGMFAARREGVARRGQLR 325 LRDLFA IFFL IG SVDP +L+ MLP AL LAA TAATKVATG+FAAR +GVARRGQLR Sbjct 266 LRDLFAAIFFLAIGYSVDPHELIPMLPAALILAAATAATKVATGIFAARHDGVARRGQLR 325 Query 326 AGTALVARGEFSLIIIGLAGASIPGVAALATAYVFVMAIVGPILARYTG 374 AGTAL+ARGEFSLIIIGLAG+S+P VAALAT+YVF+MAI GP+LARYTG Sbjct 326 AGTALIARGEFSLIIIGLAGSSLPAVAALATSYVFIMAIAGPVLARYTG 374 >gi|118472492|ref|YP_887967.1| transporter monovalent cation:proton antiporter-2 (CPA2) family protein [Mycobacterium smegmatis str. MC2 155] gi|118173779|gb|ABK74675.1| transporter, monovalent cation:proton antiporter-2 (CPA2) family protein [Mycobacterium smegmatis str. MC2 155] Length=381 Score = 459 bits (1181), Expect = 3e-127, Method: Compositional matrix adjust. Identities = 276/374 (74%), Positives = 310/374 (83%), Gaps = 0/374 (0%) Query 1 VEVSRALLFELGVLLAVLAVLGAVARRFALSPIPVYLLAGLSLGNGGILGVAAAGEFIAT 60 +EVS ALL ELGV+L L VLG ARRFALSPIP+YL+AGL+LG GG+ V A EF+ T Sbjct 1 MEVSGALLLELGVILVALTVLGTAARRFALSPIPLYLVAGLALGEGGLAPVPATVEFVNT 60 Query 61 GAPIGVVLLLLALGLEFSATEFASSLRHHLPSAGVDIVLNATPGAVAGWLLGLDGVAILG 120 GA IGVVLLLL LGLEFS EFASSLR HLPSA +D+VLNA PGA+AGWLL L V IL Sbjct 61 GASIGVVLLLLTLGLEFSIGEFASSLRRHLPSAWIDLVLNALPGAIAGWLLDLGAVGILA 120 Query 121 LAGVTYISSSGVIARLLEDLRRLGNRETPAVLSVLVLEDFAMAAYLPLFAVLATDGSWLE 180 LAGVTYISSSGVIARLL DLRRLGNRETPAVLS+LVLEDFAMAAYLPL AVLA G+ L Sbjct 121 LAGVTYISSSGVIARLLGDLRRLGNRETPAVLSILVLEDFAMAAYLPLLAVLAAGGTLLH 180 Query 181 AVVGMTVAIAALLGAFAASYRWGHHVGRLVTHPDSEQLLLRVLGITLIVAAVAESLHASA 240 A++GM VAIAAL+ AF SYRWGHHV R V+HPD+EQLLLRVLG+TLIVAA+AE +HASA Sbjct 181 ALLGMAVAIAALVVAFVVSYRWGHHVTRFVSHPDNEQLLLRVLGLTLIVAALAEFIHASA 240 Query 241 AVGAFLVGLTLTGETADRARMVLTPLRDLFATIFFLGIGLSVDPGKLVSMLPVALALAAV 300 AVGAFLVGLTLTG++A RAR+VL+PLRDLFA IFFL IGLSV P L+ MLP A LA V Sbjct 241 AVGAFLVGLTLTGDSAHRARLVLSPLRDLFAAIFFLAIGLSVHPSDLIPMLPAAFVLAVV 300 Query 301 TAATKVATGMFAARREGVARRGQLRAGTALVARGEFSLIIIGLAGASIPGVAALATAYVF 360 TA TKV TG FAARR+GVAR GQLRAGTAL+ARGEFSL+IIGL G + + A+AT YVF Sbjct 301 TAGTKVLTGQFAARRDGVARAGQLRAGTALIARGEFSLVIIGLVGQTYERLEAIATPYVF 360 Query 361 VMAIVGPILARYTG 374 ++AI GP+L RY G Sbjct 361 ILAIAGPVLTRYLG 374 >gi|134101702|ref|YP_001107363.1| sodium/hydrogen exchanger [Saccharopolyspora erythraea NRRL 2338] gi|291003128|ref|ZP_06561101.1| sodium/hydrogen exchanger [Saccharopolyspora erythraea NRRL 2338] gi|133914325|emb|CAM04438.1| sodium/hydrogen exchanger [Saccharopolyspora erythraea NRRL 2338] Length=387 Score = 370 bits (950), Expect = 2e-100, Method: Compositional matrix adjust. Identities = 222/374 (60%), Positives = 273/374 (73%), Gaps = 4/374 (1%) Query 1 VEVSRALLFELGVLLAVLAVLGAVARRFALSPIPVYLLAGLSLGNGGILGVAAAGEFIAT 60 + S ALL ELG++LAVL G + RRF +SP+P+YLL GL +G GG+ + AAGEFI Sbjct 1 MHTSVALLLELGIVLAVLGAAGTITRRFGVSPVPLYLLVGLLMGEGGVAPLPAAGEFIEV 60 Query 61 GAPIGVVLLLLALGLEFSATEFASSLRHHLPSAGVDIVLNATPGAVAGWLLGLDGVAILG 120 GA IGVVLLLL+LGLEFS EF +LR H+PS VD+V NA PGA+ GWLLGLD I+ Sbjct 61 GASIGVVLLLLSLGLEFSVEEFTVTLRRHVPSGLVDMVANAAPGALTGWLLGLDATGIVA 120 Query 121 LAGVTYISSSGVIARLLEDLRRLGNRETPAVLSVLVLEDFAMAAYLPLFAVLATDGSWLE 180 LAGVT++SSS +++RLL+DL RL RETP VLS+L+LEDFAMA YLP+ AVLA G L Sbjct 121 LAGVTWVSSSTIVSRLLDDLHRLAYRETPVVLSILLLEDFAMAVYLPILAVLAAGGGLLH 180 Query 181 AVVGMTVAIAALLGAFAASYRWGHHVGRLVTHPDSEQLLLRVLGITLIVAAVAESLHASA 240 + + VA+ L A A S+RWGH VGRLV D+EQLLLR++G++LIVAA AE SA Sbjct 181 GMASVAVAVGVLAVALAVSHRWGHRVGRLVDDRDTEQLLLRIIGLSLIVAAAAELAGTSA 240 Query 241 AVGAFLVGLTLTGETADRARMVLTPLRDLFATIFFLGIGLSVDPGKLVSMLPVALALAAV 300 AVGAFLVGL +TG A R R+V+ PLRDLFA FFL IGLS+ P LV +LPVALALA V Sbjct 241 AVGAFLVGLAVTGPLASRLRVVIAPLRDLFAAAFFLAIGLSMPPATLVPLLPVALALAVV 300 Query 301 TAATKVATGMFAARREGVARRGQLRAGTALVARGEFSLIIIGLAGASIPG--VAALATAY 358 + TK+ TG +AA R G RG+LRAGT L RGEFS+II+GL ++PG + LATAY Sbjct 301 STGTKILTGWYAAGRHGAGPRGRLRAGTVLSVRGEFSIIIVGL--VALPGSPLGPLATAY 358 Query 359 VFVMAIVGPILARY 372 V V+AI GP+L + Sbjct 359 VLVLAIAGPLLTWW 372 >gi|258652832|ref|YP_003201988.1| sodium/hydrogen exchanger [Nakamurella multipartita DSM 44233] gi|258556057|gb|ACV78999.1| sodium/hydrogen exchanger [Nakamurella multipartita DSM 44233] Length=373 Score = 367 bits (943), Expect = 1e-99, Method: Compositional matrix adjust. Identities = 228/373 (62%), Positives = 284/373 (77%), Gaps = 0/373 (0%) Query 1 VEVSRALLFELGVLLAVLAVLGAVARRFALSPIPVYLLAGLSLGNGGILGVAAAGEFIAT 60 + S ALL ELG++LAVL+ LGA+ARRFAL+PIP+YLLAGL LG GG+ V AA EF+ Sbjct 1 MHTSIALLLELGIILAVLSALGALARRFALTPIPLYLLAGLLLGEGGLATVPAAAEFVEI 60 Query 61 GAPIGVVLLLLALGLEFSATEFASSLRHHLPSAGVDIVLNATPGAVAGWLLGLDGVAILG 120 G IGVVLLLL LGLEFS E +SLR HLPSA +D +LNA PGA+ GWLLGLD + +L Sbjct 61 GGSIGVVLLLLTLGLEFSVVELTASLRRHLPSALLDGLLNAAPGALVGWLLGLDPLGMLA 120 Query 121 LAGVTYISSSGVIARLLEDLRRLGNRETPAVLSVLVLEDFAMAAYLPLFAVLATDGSWLE 180 LAG T++SSSG+++RLL DL RLGNRET AVLSVLVLEDFAMA YLP AVLA G+ Sbjct 121 LAGATWVSSSGIVSRLLGDLDRLGNRETAAVLSVLVLEDFAMAVYLPPLAVLAAGGAGWR 180 Query 181 AVVGMTVAIAALLGAFAASYRWGHHVGRLVTHPDSEQLLLRVLGITLIVAAVAESLHASA 240 A+V +A AA+ AF + RW +GR ++HP+ EQLLLR+LG+TL+VA +AE ASA Sbjct 181 ALVSALLAAAAVGSAFLVTRRWSRVIGRALSHPEPEQLLLRILGVTLVVAGLAELAGASA 240 Query 241 AVGAFLVGLTLTGETADRARMVLTPLRDLFATIFFLGIGLSVDPGKLVSMLPVALALAAV 300 AVGAFLVGL L+G ADRAR+VL+PLRDLFA I+FL IG ++ P L+ + PVAL LA V Sbjct 241 AVGAFLVGLCLSGPVADRARVVLSPLRDLFAAIYFLAIGFAIAPAALLPVWPVALGLALV 300 Query 301 TAATKVATGMFAARREGVARRGQLRAGTALVARGEFSLIIIGLAGASIPGVAALATAYVF 360 T ATK+ +G +AA R+GV RRGQLRAG AL+ RGEFSL+I+GL ++P + L AYV Sbjct 301 TMATKILSGAYAASRDGVGRRGQLRAGVALIPRGEFSLVIVGLTATAVPRLEPLVAAYVL 360 Query 361 VMAIVGPILARYT 373 ++A VGP++ R+T Sbjct 361 IVATVGPVIVRFT 373 >gi|289759376|ref|ZP_06518754.1| integral membrane transporter [Mycobacterium tuberculosis T85] gi|289714940|gb|EFD78952.1| integral membrane transporter [Mycobacterium tuberculosis T85] Length=213 Score = 322 bits (826), Expect = 6e-86, Method: Compositional matrix adjust. Identities = 175/177 (99%), Positives = 176/177 (99%), Gaps = 0/177 (0%) Query 1 VEVSRALLFELGVLLAVLAVLGAVARRFALSPIPVYLLAGLSLGNGGILGVAAAGEFIAT 60 +EVSRALLFELGVLLAVLAVLGAVARRFALSPIPVYLLAGLSLGNGGILGVAAAGEFIAT Sbjct 1 MEVSRALLFELGVLLAVLAVLGAVARRFALSPIPVYLLAGLSLGNGGILGVAAAGEFIAT 60 Query 61 GAPIGVVLLLLALGLEFSATEFASSLRHHLPSAGVDIVLNATPGAVAGWLLGLDGVAILG 120 GAPIGVVLLLLALGLEFSATEFASSLRHHLPSAGVDIVLNA PGAVAGWLLGLDGVAILG Sbjct 61 GAPIGVVLLLLALGLEFSATEFASSLRHHLPSAGVDIVLNAAPGAVAGWLLGLDGVAILG 120 Query 121 LAGVTYISSSGVIARLLEDLRRLGNRETPAVLSVLVLEDFAMAAYLPLFAVLATDGS 177 LAGVTYISSSGVIARLLEDLRRLGNRETPAVLSVLVLEDFAMAAYLPLFAVLATDGS Sbjct 121 LAGVTYISSSGVIARLLEDLRRLGNRETPAVLSVLVLEDFAMAAYLPLFAVLATDGS 177 >gi|302554587|ref|ZP_07306929.1| transmembrane transporter [Streptomyces viridochromogenes DSM 40736] gi|302472205|gb|EFL35298.1| transmembrane transporter [Streptomyces viridochromogenes DSM 40736] Length=406 Score = 318 bits (816), Expect = 8e-85, Method: Compositional matrix adjust. Identities = 203/372 (55%), Positives = 261/372 (71%), Gaps = 2/372 (0%) Query 4 SRALLFELGVLLAVLAVLGAVARRFALSPIPVYLLAGLSLGNGGILGVAAAGEFIATGAP 63 S LL E G ++ L +LG A RF LSPIP+YLLAGL+ G GG+L + A+ EF+ATGA Sbjct 3 SAVLLIEFGSIILGLGLLGRFAGRFRLSPIPLYLLAGLAFGEGGLLPLGASEEFVATGAE 62 Query 64 IGVVLLLLALGLEFSATEFASSLRHHLPSAGVDIVLNATPGAVAGWLLGLDGVAILGLAG 123 IGV+LLLL LGLE++A++ S+L+ H PS VD LNA PGA LLG VA + LAG Sbjct 63 IGVILLLLMLGLEYTASDLVSNLKTHYPSGLVDCALNALPGAAVALLLGWGPVAAVVLAG 122 Query 124 VTYISSSGVIARLLEDLRRLGNRETPAVLSVLVLEDFAMAAYLPLFAVLATDGSWLEAVV 183 VT+ISSSGVIA++L DL R+GNRETP +LSVLVLED AMA YLP+ L L V Sbjct 123 VTWISSSGVIAKVLGDLGRVGNRETPVILSVLVLEDLAMAVYLPIVTALVAGVGLLAGSV 182 Query 184 GMTVAIAALLGAFAASYRWGHHVGRLVTHPDSEQLLLRVLGITLIVAAVAESLHASAAVG 243 + +A+ A + R+G + R V+ D E+LLL VLG+T++VA VA+ L SAAVG Sbjct 183 TLAIALGAAGLVLFLAVRYGRVISRFVSSDDPEKLLLVVLGLTILVAGVAQQLQVSAAVG 242 Query 244 AFLVGLTLTGETADRARMVLTPLRDLFATIFFLGIGLSVDPGKLVSMLPVALALAAVTAA 303 AFLVG+ L+GE A+ A +L+PLRDLFA +FF+ GL DP + +L ALALA VTA Sbjct 243 AFLVGIALSGEVAEGAHTLLSPLRDLFAAVFFVFFGLHTDPSSIPPVLLPALALAVVTAL 302 Query 304 TKVATGMFAARREGVARRGQLRAGTALVARGEFSLIIIGLA-GASI-PGVAALATAYVFV 361 TK+ATG +AARR G++ +G+ RAG ALVARGEFS++I GLA A I P + LATAYV + Sbjct 303 TKIATGYWAARRAGISVKGRWRAGGALVARGEFSIVIAGLAVSAGIEPSLGPLATAYVLI 362 Query 362 MAIVGPILARYT 373 + ++GP+ ARYT Sbjct 363 LVVLGPLTARYT 374 >gi|296269726|ref|YP_003652358.1| sodium/hydrogen exchanger [Thermobispora bispora DSM 43833] gi|296092513|gb|ADG88465.1| sodium/hydrogen exchanger [Thermobispora bispora DSM 43833] Length=409 Score = 304 bits (778), Expect = 2e-80, Method: Compositional matrix adjust. Identities = 184/367 (51%), Positives = 246/367 (68%), Gaps = 3/367 (0%) Query 8 LFELGVLLAVLAVLGAVARRFALSPIPVYLLAGLSLGNGGILGVAAAGEFIATGAPIGVV 67 L ELG ++ VL ++GA+A RF++S IP+YLLAGL+ G GGIL + + EFI GA +GV+ Sbjct 5 LIELGAIVLVLGLIGALAVRFSVSAIPLYLLAGLAFGTGGILPLTTSEEFIEIGAEVGVI 64 Query 68 LLLLALGLEFSATEFASSLRHHLPSAGVDIVLNATPGAVAGWLLGLDGVAILGLAGVTYI 127 LLL LGLE++A E +LR P +D+VLNA PG + LLG V + L GVTY+ Sbjct 65 LLLFTLGLEYTADELVGTLRTSAPVGLLDLVLNAAPGVIIALLLGWGPVMAVVLGGVTYV 124 Query 128 SSSGVIARLLEDLRRLGNRETPAVLSVLVLEDFAMAAYLPLFAVLATDGSWLEAVVGMTV 187 +SSG+ A++L DL LGNRETPAVLS+LV ED MA YLP+ L ++ V + V Sbjct 125 TSSGITAKVLGDLGWLGNRETPAVLSILVFEDLTMAVYLPIVTALLAGAGLVKGAVSLAV 184 Query 188 AIAALLGAFAASYRWGHHVGRLVTHPDSEQLLLRVLGITLIVAAVAESLHASAAVGAFLV 247 A + + R GH V R + P E LLL+V G+TL+VA +A++L SAAVGAFLV Sbjct 185 AAITITVILYVALRHGHKVERFIASPSDEVLLLKVFGLTLLVAGLAQALQVSAAVGAFLV 244 Query 248 GLTLTGETADRARMVLTPLRDLFATIFFLGIGLSVDPGKLVSMLPVALALAAVTAATKVA 307 G+ L+G A +AR +LTPLRDLFA +FF+ GL DP +L +L A LA + TK A Sbjct 245 GIALSGPLAHQARQLLTPLRDLFAAVFFVFFGLHTDPTQLPPVLGAAALLAVLGVLTKAA 304 Query 308 TGMFAARREGVARRGQLRAGTALVARGEFSLIIIGL---AGASIPGVAALATAYVFVMAI 364 TG FAA+R GV+ +G+LRAG ALV RGEF+++I GL AG++ P + LA AYV ++A+ Sbjct 305 TGWFAAKRAGVSIKGRLRAGAALVPRGEFNIVIAGLAATAGSAHPQLGPLAAAYVLILAV 364 Query 365 VGPILAR 371 GP+LAR Sbjct 365 AGPLLAR 371 >gi|88855082|ref|ZP_01129747.1| putative transmembrane transport protein [marine actinobacterium PHSC20C1] gi|88815610|gb|EAR25467.1| putative transmembrane transport protein [marine actinobacterium PHSC20C1] Length=400 Score = 301 bits (772), Expect = 1e-79, Method: Compositional matrix adjust. Identities = 188/370 (51%), Positives = 252/370 (69%), Gaps = 2/370 (0%) Query 4 SRALLFELGVLLAVLAVLGAVARRFALSPIPVYLLAGLSLGNGGILGVAAAGEFIATGAP 63 + LL E+G LL VL+VLG +A RF S IP+YLLAGL++G GG+L A+ EF G+ Sbjct 4 TTQLLIEVGALLLVLSVLGRIAARFGFSAIPLYLLAGLAVGEGGLLPFQASEEFFEVGSQ 63 Query 64 IGVVLLLLALGLEFSATEFASSLRHHLPSAGVDIVLNATPGAVAGWLLGLDGVAILGLAG 123 IGV+LLL LGLE+SA E S+L+ S +D V NA PGA+ LLG + AI+ LAG Sbjct 64 IGVILLLAMLGLEYSAEELVSNLKTSRVSGILDGVFNALPGALFAILLGWEPAAIVALAG 123 Query 124 VTYISSSGVIARLLEDLRRLGNRETPAVLSVLVLEDFAMAAYLPLFAVLATDGSWLEAVV 183 VT++SSSGVIA+++ DL RLGNRETP VLS+LVLED AMA YLP+ + L L+ Sbjct 124 VTWVSSSGVIAKVVRDLGRLGNRETPTVLSILVLEDLAMAFYLPVLSALVIGAGLLQGAF 183 Query 184 GMTVAIAALLGAFAASYRWGHHVGRLVTHPDSEQLLLRVLGITLIVAAVAESLHASAAVG 243 + +A+A ++ + R G + RL+ ++E LLL V+G+T++VA +AE ++ SAAVG Sbjct 184 TVAIAVAVVMLILYLALRHGRFLSRLLPDKNAEALLLGVVGLTMLVAGLAEQVNVSAAVG 243 Query 244 AFLVGLTLTGETADRARMVLTPLRDLFATIFFLGIGLSVDPGKLVSMLPVALALAAVTAA 303 AFLVG+ ++G A ++ ++TPLRDLFA +FF+ G+S P +V +L A ALA VT A Sbjct 244 AFLVGIAISGPVAHQSAQLITPLRDLFAAVFFVFFGISTAPADIVPVLIPAAALAVVTIA 303 Query 304 TKVATGMFAARREGVARRGQLRAGTALVARGEFSLIIIGLA-GASI-PGVAALATAYVFV 361 TK +G AA+R G+A G+ RAG L RGEFS++I GLA GA I P +A LATAYV + Sbjct 304 TKTFSGYLAAKRAGIAVAGRWRAGLILTPRGEFSIVIAGLAVGAGIEPTLAPLATAYVLI 363 Query 362 MAIVGPILAR 371 I GPILAR Sbjct 364 TIIAGPILAR 373 >gi|21224127|ref|NP_629906.1| transmembrane transport protein [Streptomyces coelicolor A3(2)] gi|289768681|ref|ZP_06528059.1| transmembrane transporter [Streptomyces lividans TK24] gi|2995290|emb|CAA18319.1| putative transmembrane transport protein [Streptomyces coelicolor A3(2)] gi|289698880|gb|EFD66309.1| transmembrane transporter [Streptomyces lividans TK24] Length=411 Score = 299 bits (765), Expect = 6e-79, Method: Compositional matrix adjust. Identities = 199/372 (54%), Positives = 264/372 (71%), Gaps = 2/372 (0%) Query 4 SRALLFELGVLLAVLAVLGAVARRFALSPIPVYLLAGLSLGNGGILGVAAAGEFIATGAP 63 S LL E G ++ L +LG A R+ LSPIP+YLLAGL+ G GG+L + A+ EF+ATGA Sbjct 3 SAVLLIEFGSIILGLGLLGRFAGRYRLSPIPLYLLAGLAFGEGGLLPLGASEEFVATGAE 62 Query 64 IGVVLLLLALGLEFSATEFASSLRHHLPSAGVDIVLNATPGAVAGWLLGLDGVAILGLAG 123 IGV+LLLL LGLE++A++ ++L+ H P+ VD LNA PGAVA L+G VA + LAG Sbjct 63 IGVILLLLMLGLEYTASDLVTNLKSHYPAGLVDCALNAVPGAVAALLMGWGPVAAVVLAG 122 Query 124 VTYISSSGVIARLLEDLRRLGNRETPAVLSVLVLEDFAMAAYLPLFAVLATDGSWLEAVV 183 VT+ISSSGVIA++L DL R+GNRETP +LSVLVLED AMA YLP+ L + + Sbjct 123 VTWISSSGVIAKVLGDLGRVGNRETPVILSVLVLEDLAMAVYLPIVTALVAGAGLMTGSI 182 Query 184 GMTVAIAALLGAFAASYRWGHHVGRLVTHPDSEQLLLRVLGITLIVAAVAESLHASAAVG 243 + VA+AA + R+G + R V+ D E+LLL VLG+T++VA VA+ L SAAVG Sbjct 183 TLAVALAAAGLVLFVAVRYGRLISRFVSSDDPEKLLLVVLGLTILVAGVAQQLQVSAAVG 242 Query 244 AFLVGLTLTGETADRARMVLTPLRDLFATIFFLGIGLSVDPGKLVSMLPVALALAAVTAA 303 AFLVG+ L+GE A+ A +L+PLRDLFA +FF+ GL DP + +L ALALA +TA Sbjct 243 AFLVGIALSGEVAEGAHTLLSPLRDLFAAVFFVFFGLHTDPASIPPVLLPALALALLTAV 302 Query 304 TKVATGMFAARREGVARRGQLRAGTALVARGEFSLIIIGLA-GASI-PGVAALATAYVFV 361 TK+ATG +AARR G++ +G+ RAG ALVARGEFS++I GLA A I P + LATAYV + Sbjct 303 TKIATGYWAARRAGISVKGRWRAGGALVARGEFSIVIAGLAVSAGIEPSLGPLATAYVLI 362 Query 362 MAIVGPILARYT 373 + ++GP+ AR+T Sbjct 363 LVVLGPLTARFT 374 >gi|345000746|ref|YP_004803600.1| sodium/hydrogen exchanger [Streptomyces sp. SirexAA-E] gi|344316372|gb|AEN11060.1| sodium/hydrogen exchanger [Streptomyces sp. SirexAA-E] Length=430 Score = 298 bits (764), Expect = 8e-79, Method: Compositional matrix adjust. Identities = 193/370 (53%), Positives = 256/370 (70%), Gaps = 0/370 (0%) Query 4 SRALLFELGVLLAVLAVLGAVARRFALSPIPVYLLAGLSLGNGGILGVAAAGEFIATGAP 63 + ALL ELG ++ L ++G A R LSPIP+YLLAGL+ G GG+L + A+ EF A GA Sbjct 4 TTALLVELGSVILGLGIIGRFAGRIGLSPIPLYLLAGLAFGEGGLLPLGASEEFTAIGAE 63 Query 64 IGVVLLLLALGLEFSATEFASSLRHHLPSAGVDIVLNATPGAVAGWLLGLDGVAILGLAG 123 IGV+LLLL LGLE+SA+E +SL+ PS VD +LNATPGA+AG +LG V + LAG Sbjct 64 IGVILLLLLLGLEYSASELVTSLKTQYPSGAVDFLLNATPGAIAGLMLGWGPVGAVALAG 123 Query 124 VTYISSSGVIARLLEDLRRLGNRETPAVLSVLVLEDFAMAAYLPLFAVLATDGSWLEAVV 183 VT+ISSSGVIA+++ D+ RLGNRETP +L VLV+ED AMA YLPL + + Sbjct 124 VTWISSSGVIAKVMTDMGRLGNRETPVILGVLVIEDLAMAVYLPLLTAMLAGVGLAGGSI 183 Query 184 GMTVAIAALLGAFAASYRWGHHVGRLVTHPDSEQLLLRVLGITLIVAAVAESLHASAAVG 243 + +A+ + + R G + R V+ + E LLL VLG+T++VA VA+ L SAAVG Sbjct 184 ALLIALGTVGFVLYLALRHGRLISRAVSSDNPEMLLLVVLGLTVLVAGVAQQLQVSAAVG 243 Query 244 AFLVGLTLTGETADRARMVLTPLRDLFATIFFLGIGLSVDPGKLVSMLPVALALAAVTAA 303 AFLVG+ L+GE A+ AR +LTPLRDLFA +FF+ GLS DP ++ +L A LA VT Sbjct 244 AFLVGIALSGEVAEGARKLLTPLRDLFAAVFFVFFGLSTDPAEIPPVLLPAALLAVVTVF 303 Query 304 TKVATGMFAARREGVARRGQLRAGTALVARGEFSLIIIGLAGASIPGVAALATAYVFVMA 363 TK+ TG +A+RR G+ RG+ RAG LVARGEFS++I GLA A+ P + +ATAYV ++ Sbjct 304 TKIGTGWYASRRAGIGPRGRWRAGGTLVARGEFSIVIAGLAVATEPRIGPIATAYVLILV 363 Query 364 IVGPILARYT 373 IVGP+ AR+T Sbjct 364 IVGPLTARWT 373 >gi|320009855|gb|ADW04705.1| sodium/hydrogen exchanger [Streptomyces flavogriseus ATCC 33331] Length=415 Score = 298 bits (762), Expect = 1e-78, Method: Compositional matrix adjust. Identities = 194/370 (53%), Positives = 255/370 (69%), Gaps = 0/370 (0%) Query 4 SRALLFELGVLLAVLAVLGAVARRFALSPIPVYLLAGLSLGNGGILGVAAAGEFIATGAP 63 + ALL ELG ++ L ++G A R LSPIP+YLLAGL+ G GG+L + A+ EF A GA Sbjct 4 TTALLVELGSVILGLGIIGRFAGRIGLSPIPLYLLAGLAFGEGGLLPLGASEEFTAIGAE 63 Query 64 IGVVLLLLALGLEFSATEFASSLRHHLPSAGVDIVLNATPGAVAGWLLGLDGVAILGLAG 123 IGV+LLLL LGLE+SA+E +SL+ PS VD VLNATPGA AG +LG V + LAG Sbjct 64 IGVILLLLLLGLEYSASELVTSLKTQYPSGAVDFVLNATPGAAAGLMLGWGPVGAVALAG 123 Query 124 VTYISSSGVIARLLEDLRRLGNRETPAVLSVLVLEDFAMAAYLPLFAVLATDGSWLEAVV 183 VT+ISSSGVIA+++ D+ RLGNRETP +L VLV+ED AMA YLPL + + Sbjct 124 VTWISSSGVIAKVMTDMGRLGNRETPVILGVLVIEDLAMAVYLPLLTAMLAGVGLAGGSI 183 Query 184 GMTVAIAALLGAFAASYRWGHHVGRLVTHPDSEQLLLRVLGITLIVAAVAESLHASAAVG 243 + +A+ + + R G + R V+ + E LLL VLG+T++VA VA+ L SAAVG Sbjct 184 ALLIALGTVGFVLYLALRHGRLISRAVSSDNPEMLLLVVLGLTVLVAGVAQQLQVSAAVG 243 Query 244 AFLVGLTLTGETADRARMVLTPLRDLFATIFFLGIGLSVDPGKLVSMLPVALALAAVTAA 303 AFLVG+ L+GE A+ AR +LTPLRDLFA +FF+ GLS DP ++ +L A LA VT Sbjct 244 AFLVGIALSGEVAEGARKLLTPLRDLFAAVFFVFFGLSTDPAEIPPVLLPAALLAIVTVF 303 Query 304 TKVATGMFAARREGVARRGQLRAGTALVARGEFSLIIIGLAGASIPGVAALATAYVFVMA 363 TK+ TG +A+RR G+ RG+ RAG LVARGEFS++I GLA A+ P + +ATAYV ++ Sbjct 304 TKIGTGWYASRRAGIGPRGRWRAGGTLVARGEFSIVIAGLAVATEPRIGPIATAYVLILV 363 Query 364 IVGPILARYT 373 IVGP+ AR+T Sbjct 364 IVGPLTARWT 373 >gi|256375747|ref|YP_003099407.1| sodium/hydrogen exchanger [Actinosynnema mirum DSM 43827] gi|255920050|gb|ACU35561.1| sodium/hydrogen exchanger [Actinosynnema mirum DSM 43827] Length=393 Score = 297 bits (760), Expect = 2e-78, Method: Compositional matrix adjust. Identities = 183/367 (50%), Positives = 249/367 (68%), Gaps = 3/367 (0%) Query 8 LFELGVLLAVLAVLGAVARRFALSPIPVYLLAGLSLGNGGILGVAAAGEFIATGAPIGVV 67 L +LG + L VLG +A + +SPIP+YL+ GL+ G GG++ + EF + IGV+ Sbjct 8 LIQLGAIFFGLGVLGRLAWKIGISPIPLYLIGGLAFGEGGLVPLHGIEEFTHIASEIGVI 67 Query 68 LLLLALGLEFSATEFASSLRHHLPSAGVDIVLNATPGAVAGWLLGLDGVAILGLAGVTYI 127 LLLL LGLE+SA+E + L+ + VDIVLNATPGAV G LLG V L +AGVTYI Sbjct 68 LLLLLLGLEYSASELMTGLKRSWTAGVVDIVLNATPGAVVGLLLGWGPVGALAMAGVTYI 127 Query 128 SSSGVIARLLEDLRRLGNRETPAVLSVLVLEDFAMAAYLPLFAVLATDGSWLEAVVGMTV 187 SSSG+IA++L DL RLGNRETP +LSVLV ED AMA YLP+ + S++ + + + Sbjct 128 SSSGIIAKVLGDLGRLGNRETPVILSVLVFEDLAMALYLPILTTVLAGVSFVSGLTAVGI 187 Query 188 AIAALLGAFAASYRWGHHVGRLVTHPDSEQLLLRVLGITLIVAAVAESLHASAAVGAFLV 247 ++AA+ + ++G +V +V PD E LL+VLG L+VA +A L SAAVGAFL+ Sbjct 188 SLAAITVVLVVALKYGRYVSAVVDSPDPEVFLLKVLGAALLVAGIASQLQVSAAVGAFLL 247 Query 248 GLTLTGETADRARMVLTPLRDLFATIFFLGIGLSVDPGKLVSMLPVALALAAVTAATKVA 307 G+ ++G TA+ A +L PLRDLFA +FF+ GL+ +P + +L +AL LAAVT TKV Sbjct 248 GIAISGSTAENATRMLEPLRDLFAAMFFVVFGLNTEPSSIPPVLALALGLAAVTTVTKVM 307 Query 308 TGMFAARREGVARRGQLRAGTALVARGEFSLIIIGL---AGASIPGVAALATAYVFVMAI 364 TG +AA+R+G+ G+ RAG ALVARGEFS++I L +GA +AALATAYV +MA+ Sbjct 308 TGAWAAKRQGIGPMGRARAGAALVARGEFSIVIASLTVASGAVDGELAALATAYVLLMAV 367 Query 365 VGPILAR 371 GP+ AR Sbjct 368 FGPVAAR 374 >gi|269124360|ref|YP_003297730.1| sodium/hydrogen exchanger [Thermomonospora curvata DSM 43183] gi|268309318|gb|ACY95692.1| sodium/hydrogen exchanger [Thermomonospora curvata DSM 43183] Length=436 Score = 296 bits (759), Expect = 3e-78, Method: Compositional matrix adjust. Identities = 186/393 (48%), Positives = 252/393 (65%), Gaps = 20/393 (5%) Query 8 LFELGVLLAVLAVLGAVARRFALSPIPVYLLAGLSLGNGGILGVAAAGEFIATGAPIGVV 67 L ELG ++ L +LG++A RF++S IP+YL+AGL+ G+GGIL + + EF++ GA +GV+ Sbjct 8 LIELGAIILALGLLGSIAVRFSISAIPLYLIAGLAFGSGGILPLTDSEEFVSLGAEVGVI 67 Query 68 LLLLALGLEFSATEFASSLRHHLPSAGVDIVLNATPGAVAGWLLGLDGVAILGLAGVTYI 127 LLL LGLE+SA E +LR P D+VLNA PG + L+G VA L L GVTY+ Sbjct 68 LLLFTLGLEYSADELVGTLRTSAPVGLADLVLNAAPGVIVALLMGWGPVAALALGGVTYV 127 Query 128 SSSGVIARLLEDLRRLGNRETPAVLSVLVLEDFAMAAYLPLFAVLATD-----GSWLEAV 182 +SSG+ A+++ DL LGNRETPAVLSVLV ED MA YLP+ + G+ A+ Sbjct 128 TSSGITAKVMGDLGWLGNRETPAVLSVLVFEDLTMAVYLPILTTVLVGAGLAAGAQSLAI 187 Query 183 VGMTVAIAALLGAFAASYRWGHHVGRLVTHPDSEQLLLRVLGITLIVAAVAESLHASAAV 242 +TVA+ + + R+G V R V P+ E LLL+VLG+T++VA +A+ L SAAV Sbjct 188 AAVTVAVILFI-----ALRYGTAVERFVASPNDEVLLLKVLGLTVLVAGLAQQLQVSAAV 242 Query 243 GAFLVGLTLTGETADRARMVLTPLRDLFATIFFLGIGLSVDPGKLVSMLPVALALAAVTA 302 GAFLVG+ L+G A AR ++TPL+DLFA +FF+ GL DP L +L VA LA + Sbjct 243 GAFLVGIALSGPLAHTAREIITPLKDLFAAVFFVFFGLHTDPATLPPVLGVAALLAVLGI 302 Query 303 ATKVATGMFAARREGVARRGQLRAGTALVARGEFSLIIIGLA--GASIPGVAALATAYVF 360 ATK+ TG AARR GV +G+LRAG +L RGEF+++I GLA G P + ALA AYV Sbjct 303 ATKLGTGWLAARRAGVGLKGRLRAGVSLAPRGEFNIVIAGLAVSGGVDPRLGALAAAYVL 362 Query 361 VMAIVGPILAR--------YTGGGLPAAAVASN 385 ++AI P+LAR G G P A + + Sbjct 363 ILAIASPLLARLAEPLARKIEGRGKPQAQIDED 395 >gi|284991247|ref|YP_003409801.1| sodium/hydrogen exchanger [Geodermatophilus obscurus DSM 43160] gi|284064492|gb|ADB75430.1| sodium/hydrogen exchanger [Geodermatophilus obscurus DSM 43160] Length=387 Score = 295 bits (754), Expect = 1e-77, Method: Compositional matrix adjust. Identities = 208/342 (61%), Positives = 247/342 (73%), Gaps = 1/342 (0%) Query 31 SPIPVYLLAGLSLGNGGILGVAAAGEFIATGAPIGVVLLLLALGLEFSATEFASSLRHHL 90 S +P L+A L+LG GG++ +A + FI A IGVVLLLLALGLEFSA E +SLRHH Sbjct 31 SSVPFVLVAALALGEGGVVPLATSEPFIEAAAEIGVVLLLLALGLEFSADELFASLRHHG 90 Query 91 PSAGVDIVLNATPGAVAGWLLGLDGVAILGLAGVTYISSSGVIARLLEDLRRLGNRETPA 150 PS VD++LNA PG AG LLGL L LAGVT+ISSSG+IARLL DL RL NRETPA Sbjct 91 PSGLVDLLLNALPGFAAGLLLGLPWQGALALAGVTWISSSGIIARLLGDLGRLANRETPA 150 Query 151 VLSVLVLEDFAMAAYLPLFAVLATDGSWLEAVVGMTVAIAALLGAFAASYRWGHHVGRLV 210 VLSVLVLED AMA +LPL V G AV G +A+ A+ A A+ R GH +GRL+ Sbjct 151 VLSVLVLEDLAMALFLPLLVVALAGGGPAAAVAGTGLAVGAVTLALLAAQRQGHRLGRLL 210 Query 211 THPDSEQLLLRVLGITLIVAAVAESLHASAAVGAFLVGLTLTGETADRARMVLTPLRDLF 270 D EQLLLR++G+TL+VA +A+SL ASAAVGAFLVGL L A+RAR VL PLRDLF Sbjct 211 ASADDEQLLLRLVGLTLLVAGLAQSLGASAAVGAFLVGLALPASFAERARSVLGPLRDLF 270 Query 271 ATIFFLGIGLSVDPGKLVSMLPVALALAAVTAATKVATGMFAARREGVARRGQLRAGTAL 330 A FF+ GLS DP ++ +LP L LA VT TKVATG FAARR+GVAR G+LRAGTAL Sbjct 271 AATFFVAFGLSTDPRAVLPVLPAVLLLALVTTGTKVATGWFAARRDGVARPGRLRAGTAL 330 Query 331 VARGEFSLIIIGLA-GASIPGVAALATAYVFVMAIVGPILAR 371 VARGEFS++I GLA A +P + LAT YV V+A+ GP+L R Sbjct 331 VARGEFSIVIAGLAVTAGVPELGPLATGYVLVLAVAGPVLTR 372 >gi|326778263|ref|ZP_08237528.1| sodium/hydrogen exchanger [Streptomyces cf. griseus XylebKG-1] gi|326658596|gb|EGE43442.1| sodium/hydrogen exchanger [Streptomyces griseus XylebKG-1] Length=429 Score = 294 bits (753), Expect = 2e-77, Method: Compositional matrix adjust. Identities = 194/370 (53%), Positives = 255/370 (69%), Gaps = 0/370 (0%) Query 4 SRALLFELGVLLAVLAVLGAVARRFALSPIPVYLLAGLSLGNGGILGVAAAGEFIATGAP 63 + ALL ELG ++ L ++G A R LSPIP+YLLAGL+ G+GG++ + A+ EF GA Sbjct 4 TTALLVELGAVILGLGLVGRFAGRIGLSPIPLYLLAGLAFGHGGLIPLDASEEFTMVGAE 63 Query 64 IGVVLLLLALGLEFSATEFASSLRHHLPSAGVDIVLNATPGAVAGWLLGLDGVAILGLAG 123 IGV+LLLL LGLE+SA+E +SL+ PS VD LNATPGAVA +LG V + LAG Sbjct 64 IGVILLLLLLGLEYSASELVTSLKTQYPSGAVDFFLNATPGAVAALILGWGPVGAVALAG 123 Query 124 VTYISSSGVIARLLEDLRRLGNRETPAVLSVLVLEDFAMAAYLPLFAVLATDGSWLEAVV 183 VT+ISSSGVIA+++ DL RLGNRETP +L VLV+ED AMA YLPL + S + Sbjct 124 VTWISSSGVIAKVMTDLGRLGNRETPVILGVLVMEDLAMAIYLPLLTAMLAGVSLAGGSL 183 Query 184 GMTVAIAALLGAFAASYRWGHHVGRLVTHPDSEQLLLRVLGITLIVAAVAESLHASAAVG 243 + +A+ A+ + R G + R V+ + E LLL VLG+T++VA VA+ L SAAVG Sbjct 184 ALVIALGAVGLVLYLALRHGRLISRAVSSDNPEMLLLVVLGLTVLVAGVAQQLQVSAAVG 243 Query 244 AFLVGLTLTGETADRARMVLTPLRDLFATIFFLGIGLSVDPGKLVSMLPVALALAAVTAA 303 AFLVG+ L+GE A+ AR +LTPLRDLFA +FF+ GLS +P + +L A LA +T Sbjct 244 AFLVGIALSGEVAEGARKLLTPLRDLFAAVFFVFFGLSTNPADIPPVLLPAALLAIITTF 303 Query 304 TKVATGMFAARREGVARRGQLRAGTALVARGEFSLIIIGLAGASIPGVAALATAYVFVMA 363 TK+ TG +AARR GV RG+ RAG LVARGEFS++I GLA A+ P + +ATAYV ++ Sbjct 304 TKIGTGYYAARRAGVGSRGRWRAGGTLVARGEFSIVIAGLAVATEPRIGPIATAYVLILV 363 Query 364 IVGPILARYT 373 IVGP+ AR+T Sbjct 364 IVGPLTARWT 373 >gi|182437609|ref|YP_001825328.1| putative sodium/proton antiporter [Streptomyces griseus subsp. griseus NBRC 13350] gi|178466125|dbj|BAG20645.1| putative sodium/proton antiporter [Streptomyces griseus subsp. griseus NBRC 13350] Length=429 Score = 294 bits (753), Expect = 2e-77, Method: Compositional matrix adjust. Identities = 194/370 (53%), Positives = 255/370 (69%), Gaps = 0/370 (0%) Query 4 SRALLFELGVLLAVLAVLGAVARRFALSPIPVYLLAGLSLGNGGILGVAAAGEFIATGAP 63 + ALL ELG ++ L ++G A R LSPIP+YLLAGL+ G+GG++ + A+ EF GA Sbjct 4 TTALLVELGAVILGLGLVGRFAGRIGLSPIPLYLLAGLAFGHGGLIPLDASEEFTMVGAE 63 Query 64 IGVVLLLLALGLEFSATEFASSLRHHLPSAGVDIVLNATPGAVAGWLLGLDGVAILGLAG 123 IGV+LLLL LGLE+SA+E +SL+ PS VD LNATPGAVA +LG V + LAG Sbjct 64 IGVILLLLLLGLEYSASELVTSLKTQYPSGAVDFFLNATPGAVAALILGWGPVGAVALAG 123 Query 124 VTYISSSGVIARLLEDLRRLGNRETPAVLSVLVLEDFAMAAYLPLFAVLATDGSWLEAVV 183 VT+ISSSGVIA+++ DL RLGNRETP +L VLV+ED AMA YLPL + S + Sbjct 124 VTWISSSGVIAKVMTDLGRLGNRETPVILGVLVMEDLAMAIYLPLLTAMLAGVSLAGGSL 183 Query 184 GMTVAIAALLGAFAASYRWGHHVGRLVTHPDSEQLLLRVLGITLIVAAVAESLHASAAVG 243 + +A+ A+ + R G + R V+ + E LLL VLG+T++VA VA+ L SAAVG Sbjct 184 ALVIALGAVGLVLYLALRHGRLISRAVSSDNPEMLLLVVLGLTVLVAGVAQQLQVSAAVG 243 Query 244 AFLVGLTLTGETADRARMVLTPLRDLFATIFFLGIGLSVDPGKLVSMLPVALALAAVTAA 303 AFLVG+ L+GE A+ AR +LTPLRDLFA +FF+ GLS +P + +L A LA +T Sbjct 244 AFLVGIALSGEVAEGARKLLTPLRDLFAAVFFVFFGLSTNPADIPPVLLPAALLAIITTF 303 Query 304 TKVATGMFAARREGVARRGQLRAGTALVARGEFSLIIIGLAGASIPGVAALATAYVFVMA 363 TK+ TG +AARR GV RG+ RAG LVARGEFS++I GLA A+ P + +ATAYV ++ Sbjct 304 TKIGTGYYAARRAGVGSRGRWRAGGTLVARGEFSIVIAGLAVATEPRIGPIATAYVLILV 363 Query 364 IVGPILARYT 373 IVGP+ AR+T Sbjct 364 IVGPLTARWT 373 >gi|289759375|ref|ZP_06518753.1| integral membrane transporter [Mycobacterium tuberculosis T85] gi|289714939|gb|EFD78951.1| integral membrane transporter [Mycobacterium tuberculosis T85] Length=159 Score = 294 bits (752), Expect = 2e-77, Method: Compositional matrix adjust. Identities = 158/159 (99%), Positives = 159/159 (100%), Gaps = 0/159 (0%) Query 227 LIVAAVAESLHASAAVGAFLVGLTLTGETADRARMVLTPLRDLFATIFFLGIGLSVDPGK 286 +IVAAVAESLHASAAVGAFLVGLTLTGETADRARMVLTPLRDLFATIFFLGIGLSVDPGK Sbjct 1 MIVAAVAESLHASAAVGAFLVGLTLTGETADRARMVLTPLRDLFATIFFLGIGLSVDPGK 60 Query 287 LVSMLPVALALAAVTAATKVATGMFAARREGVARRGQLRAGTALVARGEFSLIIIGLAGA 346 LVSMLPVALALAAVTAATKVATGMFAARREGVARRGQLRAGTALVARGEFSLIIIGLAGA Sbjct 61 LVSMLPVALALAAVTAATKVATGMFAARREGVARRGQLRAGTALVARGEFSLIIIGLAGA 120 Query 347 SIPGVAALATAYVFVMAIVGPILARYTGGGLPAAAVASN 385 SIPGVAALATAYVFVMAIVGPILARYTGGGLPAAAVASN Sbjct 121 SIPGVAALATAYVFVMAIVGPILARYTGGGLPAAAVASN 159 >gi|229491296|ref|ZP_04385122.1| sodium/hydrogen exchanger [Rhodococcus erythropolis SK121] gi|229321835|gb|EEN87630.1| sodium/hydrogen exchanger [Rhodococcus erythropolis SK121] Length=390 Score = 293 bits (751), Expect = 2e-77, Method: Compositional matrix adjust. Identities = 187/367 (51%), Positives = 247/367 (68%), Gaps = 3/367 (0%) Query 8 LFELGVLLAVLAVLGAVARRFALSPIPVYLLAGLSLGNGGILGVAAAGEFIATGAPIGVV 67 L ELG + L +LG +A R +SPIP YL+ GL G GG + + GEF + IG+V Sbjct 8 LIELGAVFFALGLLGRLAARVGMSPIPFYLIGGLCFGQGGFIQLGDIGEFSHLASEIGIV 67 Query 68 LLLLALGLEFSATEFASSLRHHLPSAGVDIVLNATPGAVAGWLLGLDGVAILGLAGVTYI 127 LLLL LGLE++A E + L+ + VDIVLNATPGAV G +LG V +AGVTYI Sbjct 68 LLLLLLGLEYTAAELVTGLKRSRVAGIVDIVLNATPGAVVGLMLGWGVVGATVMAGVTYI 127 Query 128 SSSGVIARLLEDLRRLGNRETPAVLSVLVLEDFAMAAYLPLFAVLATDGSWLEAVVGMTV 187 SSSG+IA++L DL RLGNRETP VLS+LV ED AMA YLP+ + S++ + + + Sbjct 128 SSSGIIAKVLSDLGRLGNRETPVVLSILVFEDLAMALYLPILTAMLAGVSFMGGLEAVGI 187 Query 188 AIAALLGAFAASYRWGHHVGRLVTHPDSEQLLLRVLGITLIVAAVAESLHASAAVGAFLV 247 ++ + + R+G +V L+ PDSE LLL++LG L+VA ++ ++ SAAVGAFL+ Sbjct 188 SLLVITVVLVVALRYGRYVSALLDSPDSETLLLKLLGAALLVAGISSAMQVSAAVGAFLL 247 Query 248 GLTLTGETADRARMVLTPLRDLFATIFFLGIGLSVDPGKLVSMLPVALALAAVTAATKVA 307 G+ ++G TA A VL PLRDLFA +FF+ GL+ DP + +L A LA VTA TK+ Sbjct 248 GIAISGSTAHNASRVLEPLRDLFAAMFFVVFGLNTDPSSIPPVLGWAAILAVVTAITKLV 307 Query 308 TGMFAARREGVARRGQLRAGTALVARGEFSLIIIGL---AGASIPGVAALATAYVFVMAI 364 TG +AARR+GVAR GQ RAG AL+ARGEFS+II GL AGA +AALATAYV +MA+ Sbjct 308 TGAWAARRQGVARMGQARAGAALIARGEFSIIIAGLAVSAGAVDAELAALATAYVLLMAV 367 Query 365 VGPILAR 371 +GP+ AR Sbjct 368 IGPVAAR 374 >gi|291446010|ref|ZP_06585400.1| transmembrane transport protein [Streptomyces roseosporus NRRL 15998] gi|291348957|gb|EFE75861.1| transmembrane transport protein [Streptomyces roseosporus NRRL 15998] Length=424 Score = 293 bits (750), Expect = 3e-77, Method: Compositional matrix adjust. Identities = 193/370 (53%), Positives = 254/370 (69%), Gaps = 0/370 (0%) Query 4 SRALLFELGVLLAVLAVLGAVARRFALSPIPVYLLAGLSLGNGGILGVAAAGEFIATGAP 63 + ALL ELG ++ L ++G A R LSPIP+YLLAGL+ G+GG++ + A+ EF GA Sbjct 4 TTALLVELGAVILGLGLVGRFAGRIGLSPIPLYLLAGLAFGHGGLIPLKASEEFTMVGAE 63 Query 64 IGVVLLLLALGLEFSATEFASSLRHHLPSAGVDIVLNATPGAVAGWLLGLDGVAILGLAG 123 IGV+LLLL LGLE+SA+E +SL+ PS VD LNA PGAVA +LG V + LAG Sbjct 64 IGVILLLLLLGLEYSASELVTSLKTQYPSGAVDFALNAIPGAVAALILGWGAVGAVALAG 123 Query 124 VTYISSSGVIARLLEDLRRLGNRETPAVLSVLVLEDFAMAAYLPLFAVLATDGSWLEAVV 183 VT+ISSSGVIA+++ DL RLGNRETP +L VLV+ED AMA YLPL + S + Sbjct 124 VTWISSSGVIAKVMTDLGRLGNRETPVILGVLVMEDLAMAVYLPLLTAMLAGVSLAGGSL 183 Query 184 GMTVAIAALLGAFAASYRWGHHVGRLVTHPDSEQLLLRVLGITLIVAAVAESLHASAAVG 243 + +A+ A+ + R G + R V+ + E LLL VLG+T++VA VA+ L SAAVG Sbjct 184 ALVIALGAVGLVLYLALRHGRLISRAVSSDNPEMLLLVVLGLTVLVAGVAQQLQVSAAVG 243 Query 244 AFLVGLTLTGETADRARMVLTPLRDLFATIFFLGIGLSVDPGKLVSMLPVALALAAVTAA 303 AFLVG+ L+GE A+ AR +LTPLRDLFA +FF+ GLS +P + +L A LA +T Sbjct 244 AFLVGIALSGEVAEGARKLLTPLRDLFAAVFFVFFGLSTNPADIPPVLLPAALLAIITTF 303 Query 304 TKVATGMFAARREGVARRGQLRAGTALVARGEFSLIIIGLAGASIPGVAALATAYVFVMA 363 TK+ TG +AARR GV RG+ RAG LVARGEFS++I GLA A+ P + +ATAYV ++ Sbjct 304 TKIGTGYYAARRAGVGSRGRWRAGGTLVARGEFSIVIAGLAVATEPRIGPIATAYVLILV 363 Query 364 IVGPILARYT 373 IVGP+ AR+T Sbjct 364 IVGPLTARWT 373 >gi|226306301|ref|YP_002766261.1| hypothetical protein RER_28140 [Rhodococcus erythropolis PR4] gi|229492442|ref|ZP_04386246.1| sodium/hydrogen exchanger [Rhodococcus erythropolis SK121] gi|226185418|dbj|BAH33522.1| conserved hypothetical membrane protein [Rhodococcus erythropolis PR4] gi|229320671|gb|EEN86488.1| sodium/hydrogen exchanger [Rhodococcus erythropolis SK121] Length=390 Score = 293 bits (750), Expect = 3e-77, Method: Compositional matrix adjust. Identities = 187/367 (51%), Positives = 247/367 (68%), Gaps = 3/367 (0%) Query 8 LFELGVLLAVLAVLGAVARRFALSPIPVYLLAGLSLGNGGILGVAAAGEFIATGAPIGVV 67 L ELG + L +LG +A R +SPIP YL+ GL G GG + + GEF + IG+V Sbjct 8 LIELGAVFFALGLLGRLAARVGMSPIPFYLIGGLCFGQGGFIQLGDIGEFSHLASEIGIV 67 Query 68 LLLLALGLEFSATEFASSLRHHLPSAGVDIVLNATPGAVAGWLLGLDGVAILGLAGVTYI 127 LLLL LGLE++A E + L+ + VDIVLNATPGAV G +LG V +AGVTYI Sbjct 68 LLLLLLGLEYTAAELVTGLKRSRVAGIVDIVLNATPGAVVGLILGWGVVGATVMAGVTYI 127 Query 128 SSSGVIARLLEDLRRLGNRETPAVLSVLVLEDFAMAAYLPLFAVLATDGSWLEAVVGMTV 187 SSSG+IA++L DL RLGNRETP VLS+LV ED AMA YLP+ + S++ + + + Sbjct 128 SSSGIIAKVLSDLGRLGNRETPVVLSILVFEDLAMALYLPILTAMLAGVSFMGGLEAVGI 187 Query 188 AIAALLGAFAASYRWGHHVGRLVTHPDSEQLLLRVLGITLIVAAVAESLHASAAVGAFLV 247 ++ + + R+G +V L+ PDSE LLL++LG L+VA ++ ++ SAAVGAFL+ Sbjct 188 SLLVITVVLVVALRYGRYVSALLDSPDSETLLLKLLGAALLVAGISSAMQVSAAVGAFLL 247 Query 248 GLTLTGETADRARMVLTPLRDLFATIFFLGIGLSVDPGKLVSMLPVALALAAVTAATKVA 307 G+ ++G TA A VL PLRDLFA +FF+ GL+ DP + +L A LA VTA TK+ Sbjct 248 GIAISGSTAHNASRVLEPLRDLFAAMFFVVFGLNTDPSSIPPVLGWAAILAVVTAITKLI 307 Query 308 TGMFAARREGVARRGQLRAGTALVARGEFSLIIIGL---AGASIPGVAALATAYVFVMAI 364 TG +AARR+GVAR GQ RAG AL+ARGEFS+II GL AGA +AALATAYV +MA+ Sbjct 308 TGAWAARRQGVARMGQARAGAALIARGEFSIIIAGLAVSAGAVDAELAALATAYVLLMAV 367 Query 365 VGPILAR 371 +GP+ AR Sbjct 368 IGPVAAR 374 >gi|311894509|dbj|BAJ26917.1| putative sodium/proton antiporter [Kitasatospora setae KM-6054] Length=403 Score = 293 bits (750), Expect = 4e-77, Method: Compositional matrix adjust. Identities = 194/369 (53%), Positives = 258/369 (70%), Gaps = 2/369 (0%) Query 7 LLFELGVLLAVLAVLGAVARRFALSPIPVYLLAGLSLGNGGILGVAAAGEFIATGAPIGV 66 + ELG ++ L +LG + R+ LSPIP+YLL GL+ G GG+L ++A+ EF+ATGA IGV Sbjct 6 IFIELGAIILTLGLLGRIGSRYGLSPIPLYLLGGLAFGQGGLLPLSASEEFVATGAEIGV 65 Query 67 VLLLLALGLEFSATEFASSLRHHLPSAGVDIVLNATPGAVAGWLLGLDGVAILGLAGVTY 126 VLLLL LGLE++A + ++L+ P+ VD NA PGA LLG VA + LAGVT+ Sbjct 66 VLLLLMLGLEYTAADLVTNLKSQYPAGMVDFAFNALPGAAMALLLGWGPVAAVVLAGVTW 125 Query 127 ISSSGVIARLLEDLRRLGNRETPAVLSVLVLEDFAMAAYLPLFAVLATDGSWLEAVVGMT 186 ISSSGVIA++L DL RLGNRETP +LS+LVLED AMA YLP+ L L V + Sbjct 126 ISSSGVIAKVLGDLGRLGNRETPVILSILVLEDLAMAVYLPILTALLAGAGLLVGSVTLA 185 Query 187 VAIAALLGAFAASYRWGHHVGRLVTHPDSEQLLLRVLGITLIVAAVAESLHASAAVGAFL 246 VA+A + R+G + R V+H D E+LLL VLG+TL+VA +A+ L SAAVGAFL Sbjct 186 VALATAGAVLFVALRYGRLISRFVSHDDPEKLLLVVLGLTLLVAGIAQQLQVSAAVGAFL 245 Query 247 VGLTLTGETADRARMVLTPLRDLFATIFFLGIGLSVDPGKLVSMLPVALALAAVTAATKV 306 VG+ L+GE A+ A +L+PLRDLFA +FF+ GL+ +P + +L ALALA TA TK+ Sbjct 246 VGIALSGEAAEGAHTLLSPLRDLFAAVFFVFFGLNTNPASIPPVLLPALALAVTTALTKI 305 Query 307 ATGMFAARREGVARRGQLRAGTALVARGEFSLIIIGLAGAS--IPGVAALATAYVFVMAI 364 ATG +AARR G+A +G+ RAG ALVARGEFS++I GLA A+ P + LATAYV ++ + Sbjct 306 ATGYWAARRAGIAAKGRWRAGGALVARGEFSIVIAGLAVAAGIEPSLGPLATAYVLLLVV 365 Query 365 VGPILARYT 373 +GP+ AR+T Sbjct 366 IGPLAARWT 374 >gi|258650663|ref|YP_003199819.1| sodium/hydrogen exchanger [Nakamurella multipartita DSM 44233] gi|258553888|gb|ACV76830.1| sodium/hydrogen exchanger [Nakamurella multipartita DSM 44233] Length=388 Score = 292 bits (748), Expect = 6e-77, Method: Compositional matrix adjust. Identities = 205/378 (55%), Positives = 261/378 (70%), Gaps = 3/378 (0%) Query 1 VEVSRALLFELGVLLAVLAVLGAVARRFALSPIPVYLLAGLSLGNGGILGVAAAGEFIAT 60 + VS A L E G+LL +L + AVA + LS +P++L+AGL +G GG+L V AA F+ Sbjct 1 MHVSAAFLVEFGILLLILGAVSAVAGKLGLSAVPLFLIAGLFVGPGGLLPVPAAAPFLEA 60 Query 61 GAPIGVVLLLLALGLEFSATEFASSLRHHLPSAGVDIVLNATPGAVAGWLLGLDGVAILG 120 GA IGVVLLLL+LGLEFSA EF +LR H PS VD+VLNA PG VAG LLGL ++ Sbjct 61 GAVIGVVLLLLSLGLEFSADEFTQALRRHTPSGVVDLVLNAVPGVVAGLLLGLPVAGVVA 120 Query 121 LAGVTYISSSGVIARLLEDLRRLGNRETPAVLSVLVLEDFAMAAYLPLFAVLATDGSWLE 180 L G+T++SSSG+++R L DL RLG RETPAVLSVLVLED AMA YLP+ +L ++L Sbjct 121 LGGITWVSSSGIVSRTLSDLGRLGYRETPAVLSVLVLEDVAMAVYLPMLGILLAGTAFLA 180 Query 181 AVVGMTVAIAALLGAFAASYRW-GHHVGRLVTHPDSEQLLLRVLGITLIVAAVAESLHAS 239 + G+ VA+ AL+G S RW G +G L+TH EQ+LLR+L +TL+VA AE + S Sbjct 181 GLAGVLVAVVALIGVLMLS-RWSGPVIGWLITHDSDEQVLLRLLALTLLVAGAAEYMGIS 239 Query 240 AAVGAFLVGLTLTGETADRARMVLTPLRDLFATIFFLGIGLSVDPGKLVSMLPVALALAA 299 AAVGAFLVGL + E A+ R V+ PLRDLFA FFL G ++DP + L VA LA Sbjct 240 AAVGAFLVGLAVPAEAAESVRRVIGPLRDLFAAAFFLSFGYAIDPRDMPPALVVAALLAV 299 Query 300 VTAATKVATGMFAARREGVARRGQLRAGTALVARGEFSLIIIGLA-GASIPGVAALATAY 358 VTA TKV TG FAARR+GV RG+ RAGTAL+ARGEFS++I GLA A + + LA Y Sbjct 300 VTAVTKVITGWFAARRDGVGARGRRRAGTALIARGEFSMVIAGLAVAAGVTEIGPLAATY 359 Query 359 VFVMAIVGPILARYTGGG 376 V ++A+ G +L R +G G Sbjct 360 VLLLAVGGSLLTRLSGQG 377 >gi|328885719|emb|CCA58958.1| putative transmembrane transport protein [Streptomyces venezuelae ATCC 10712] Length=417 Score = 291 bits (745), Expect = 1e-76, Method: Compositional matrix adjust. Identities = 192/369 (53%), Positives = 254/369 (69%), Gaps = 2/369 (0%) Query 7 LLFELGVLLAVLAVLGAVARRFALSPIPVYLLAGLSLGNGGILGVAAAGEFIATGAPIGV 66 L E G ++ L +LG VA R SPIP+YLLAGL+ G GG+L + A+ EF+A GA IGV Sbjct 6 FLIEFGAIILGLGLLGRVAGRLKFSPIPLYLLAGLAFGTGGLLPMGASEEFVAIGAEIGV 65 Query 67 VLLLLALGLEFSATEFASSLRHHLPSAGVDIVLNATPGAVAGWLLGLDGVAILGLAGVTY 126 +LLLL LGLE++A++ S+L+ P+ VD LNA PGAVA L+G VA + LAGVT+ Sbjct 66 ILLLLMLGLEYTASDLVSNLKTQYPAGLVDFGLNAVPGAVAALLMGWGPVAAVVLAGVTW 125 Query 127 ISSSGVIARLLEDLRRLGNRETPAVLSVLVLEDFAMAAYLPLFAVLATDGSWLEAVVGMT 186 ISSSGVIA+++ DL R+GNRETP +LS+LVLED AMA YLP+ L S + Sbjct 126 ISSSGVIAKVMGDLGRVGNRETPVILSILVLEDLAMAVYLPIITALLAGVSLAAGSATLA 185 Query 187 VAIAALLGAFAASYRWGHHVGRLVTHPDSEQLLLRVLGITLIVAAVAESLHASAAVGAFL 246 +A+ + R+G H+ R V+ D E+LLL VLG+TL+VA +A+ L SAAVGAFL Sbjct 186 IALGVAGAVLFIAVRFGRHISRFVSSDDPEKLLLVVLGLTLLVAGIAQQLQVSAAVGAFL 245 Query 247 VGLTLTGETADRARMVLTPLRDLFATIFFLGIGLSVDPGKLVSMLPVALALAAVTAATKV 306 VG+ L+GE A+ +L+PLRDLFA +FF+ GL DP + +L ALALA VTA TK+ Sbjct 246 VGIALSGEVAEGTHTLLSPLRDLFAAVFFVFFGLHTDPASIPPVLLPALALAVVTAGTKI 305 Query 307 ATGMFAARREGVARRGQLRAGTALVARGEFSLIIIGLA-GASI-PGVAALATAYVFVMAI 364 ATG +AA+R G+ +G+ RAG LVARGEFS++I GLA A I P + LATAYV ++ + Sbjct 306 ATGYWAAKRAGIGVKGRWRAGGTLVARGEFSIVIAGLAVTAGIEPAMGPLATAYVLILVV 365 Query 365 VGPILARYT 373 +GP+ ARYT Sbjct 366 IGPLTARYT 374 >gi|239989013|ref|ZP_04709677.1| putative sodium/proton antiporter [Streptomyces roseosporus NRRL 11379] Length=418 Score = 291 bits (745), Expect = 1e-76, Method: Compositional matrix adjust. Identities = 191/367 (53%), Positives = 252/367 (69%), Gaps = 0/367 (0%) Query 7 LLFELGVLLAVLAVLGAVARRFALSPIPVYLLAGLSLGNGGILGVAAAGEFIATGAPIGV 66 +L ELG ++ L ++G A R LSPIP+YLLAGL+ G+GG++ + A+ EF GA IGV Sbjct 1 MLVELGAVILGLGLVGRFAGRIGLSPIPLYLLAGLAFGHGGLIPLKASEEFTMVGAEIGV 60 Query 67 VLLLLALGLEFSATEFASSLRHHLPSAGVDIVLNATPGAVAGWLLGLDGVAILGLAGVTY 126 +LLLL LGLE+SA+E +SL+ PS VD LNA PGAVA +LG V + LAGVT+ Sbjct 61 ILLLLLLGLEYSASELVTSLKTQYPSGAVDFALNAIPGAVAALILGWGAVGAVALAGVTW 120 Query 127 ISSSGVIARLLEDLRRLGNRETPAVLSVLVLEDFAMAAYLPLFAVLATDGSWLEAVVGMT 186 ISSSGVIA+++ DL RLGNRETP +L VLV+ED AMA YLPL + S + + Sbjct 121 ISSSGVIAKVMTDLGRLGNRETPVILGVLVMEDLAMAVYLPLLTAMLAGVSLAGGSLALV 180 Query 187 VAIAALLGAFAASYRWGHHVGRLVTHPDSEQLLLRVLGITLIVAAVAESLHASAAVGAFL 246 +A+ A+ + R G + R V+ + E LLL VLG+T++VA VA+ L SAAVGAFL Sbjct 181 IALGAVGLVLYLALRHGRLISRAVSSDNPEMLLLVVLGLTVLVAGVAQQLQVSAAVGAFL 240 Query 247 VGLTLTGETADRARMVLTPLRDLFATIFFLGIGLSVDPGKLVSMLPVALALAAVTAATKV 306 VG+ L+GE A+ AR +LTPLRDLFA +FF+ GLS +P + +L A LA +T TK+ Sbjct 241 VGIALSGEVAEGARKLLTPLRDLFAAVFFVFFGLSTNPADIPPVLLPAALLAIITTFTKI 300 Query 307 ATGMFAARREGVARRGQLRAGTALVARGEFSLIIIGLAGASIPGVAALATAYVFVMAIVG 366 TG +AARR GV RG+ RAG LVARGEFS++I GLA A+ P + +ATAYV ++ IVG Sbjct 301 GTGYYAARRAGVGSRGRWRAGGTLVARGEFSIVIAGLAVATEPRIGPIATAYVLILVIVG 360 Query 367 PILARYT 373 P+ AR+T Sbjct 361 PLTARWT 367 >gi|318060076|ref|ZP_07978799.1| transmembrane transport protein [Streptomyces sp. SA3_actG] Length=413 Score = 289 bits (739), Expect = 7e-76, Method: Compositional matrix adjust. Identities = 199/377 (53%), Positives = 256/377 (68%), Gaps = 10/377 (2%) Query 2 EVSRALLFELGVLLAVLAVLGAVARRFALSPIPVYLLAGLSLGNGGILGVAAAGEFIATG 61 + + LL ELG ++ L +LG +A R SPIP+YLLAGL+ G GG L + A+ EF+ATG Sbjct 3 DTTTELLIELGAIILGLGILGRLAGRIGFSPIPLYLLAGLAFGKGGFLPLNASEEFVATG 62 Query 62 APIGVVLLLLALGLEFSATEFASSLRHHLPSAGVDIVLNATPGAVAGWLLGLDGVAILGL 121 A IGV+LLLL LGLE+SA+E ++L+ PS VD VLNA PG V +LG VA + L Sbjct 63 AEIGVILLLLLLGLEYSASELVTNLKKQYPSGIVDFVLNALPGFVCALILGWGLVAAVAL 122 Query 122 AGVTYISSSGVIARLLEDLRRLGNRETPAVLSVLVLEDFAMAAYLP----LFAVLATDGS 177 AGVT+ISSSGVIA++L DL RLGNRETP +L VLV+ED AMA YLP L A L+ G+ Sbjct 123 AGVTWISSSGVIAKVLGDLGRLGNRETPVILGVLVIEDLAMAIYLPILTALLAGLSLGGA 182 Query 178 WLEAVVGM-TVAIAALLGAFAASYRWGHHVGRLVTHPDSEQLLLRVLGITLIVAAVAESL 236 L V+ + TV + L + R G + R V+ + E LLL VLG+T++VA VA L Sbjct 183 SLTLVISLGTVGLVLYL-----ALRHGRLISRAVSSDNPEMLLLVVLGLTVLVAGVAAEL 237 Query 237 HASAAVGAFLVGLTLTGETADRARMVLTPLRDLFATIFFLGIGLSVDPGKLVSMLPVALA 296 SAAVGAFLVG+ L+GE A+ A +L PLRDLFA +FF+ GLS +P + + AL Sbjct 238 QVSAAVGAFLVGIALSGEVAEGAHNLLAPLRDLFAAVFFVFFGLSTNPADIPPVFLTALL 297 Query 297 LAAVTAATKVATGMFAARREGVARRGQLRAGTALVARGEFSLIIIGLAGASIPGVAALAT 356 LA VT TK+ATG +AARR GV R G+ RAG LVARGEFS++I GLA + P + LAT Sbjct 298 LAVVTVLTKIATGWYAARRAGVQRAGRWRAGGTLVARGEFSIVIAGLAVGTAPEIGPLAT 357 Query 357 AYVFVMAIVGPILARYT 373 AYV ++ I+GP+ AR+T Sbjct 358 AYVLILVILGPLTARWT 374 >gi|333028627|ref|ZP_08456691.1| putative Na+/H+ exchanger family protein [Streptomyces sp. Tu6071] gi|332748479|gb|EGJ78920.1| putative Na+/H+ exchanger family protein [Streptomyces sp. Tu6071] Length=413 Score = 288 bits (738), Expect = 8e-76, Method: Compositional matrix adjust. Identities = 199/377 (53%), Positives = 256/377 (68%), Gaps = 10/377 (2%) Query 2 EVSRALLFELGVLLAVLAVLGAVARRFALSPIPVYLLAGLSLGNGGILGVAAAGEFIATG 61 + + LL ELG ++ L +LG +A R SPIP+YLLAGL+ G GG L + A+ EF+ATG Sbjct 3 DTTTELLIELGAIILGLGILGRLAGRIGFSPIPLYLLAGLAFGKGGFLPLNASEEFVATG 62 Query 62 APIGVVLLLLALGLEFSATEFASSLRHHLPSAGVDIVLNATPGAVAGWLLGLDGVAILGL 121 A IGV+LLLL LGLE+SA+E ++L+ PS VD VLNA PG V +LG VA + L Sbjct 63 AEIGVILLLLLLGLEYSASELVTNLKKQYPSGIVDFVLNALPGFVCALILGWGLVAAVAL 122 Query 122 AGVTYISSSGVIARLLEDLRRLGNRETPAVLSVLVLEDFAMAAYLP----LFAVLATDGS 177 AGVT+ISSSGVIA++L DL RLGNRETP +L VLV+ED AMA YLP L A L+ G+ Sbjct 123 AGVTWISSSGVIAKVLGDLGRLGNRETPVILGVLVIEDLAMAIYLPILTALLAGLSLGGA 182 Query 178 WLEAVVGM-TVAIAALLGAFAASYRWGHHVGRLVTHPDSEQLLLRVLGITLIVAAVAESL 236 L V+ + TV + L + R G + R V+ + E LLL VLG+T++VA VA L Sbjct 183 SLTLVISLGTVGLVLYL-----ALRHGRLISRAVSSDNPEMLLLVVLGLTVLVAGVAAEL 237 Query 237 HASAAVGAFLVGLTLTGETADRARMVLTPLRDLFATIFFLGIGLSVDPGKLVSMLPVALA 296 SAAVGAFLVG+ L+GE A+ A +L PLRDLFA +FF+ GLS +P + + AL Sbjct 238 QVSAAVGAFLVGIALSGEVAEGAHNLLAPLRDLFAAVFFVFFGLSTNPADIPPVFLTALL 297 Query 297 LAAVTAATKVATGMFAARREGVARRGQLRAGTALVARGEFSLIIIGLAGASIPGVAALAT 356 LA VT TK+ATG +AARR GV R G+ RAG LVARGEFS++I GLA + P + LAT Sbjct 298 LAVVTVLTKIATGWYAARRAGVQRAGRWRAGGTLVARGEFSIVIAGLAVGTAPEIGPLAT 357 Query 357 AYVFVMAIVGPILARYT 373 AYV ++ I+GP+ AR+T Sbjct 358 AYVLILVILGPLTARWT 374 >gi|318079258|ref|ZP_07986590.1| regulator [Streptomyces sp. SA3_actF] Length=777 Score = 285 bits (728), Expect = 1e-74, Method: Compositional matrix adjust. Identities = 199/377 (53%), Positives = 256/377 (68%), Gaps = 10/377 (2%) Query 2 EVSRALLFELGVLLAVLAVLGAVARRFALSPIPVYLLAGLSLGNGGILGVAAAGEFIATG 61 + + LL ELG ++ L +LG +A R SPIP+YLLAGL+ G GG L + A+ EF+ATG Sbjct 3 DTTTELLIELGAIILGLGILGRLAGRIGFSPIPLYLLAGLAFGKGGFLPLNASEEFVATG 62 Query 62 APIGVVLLLLALGLEFSATEFASSLRHHLPSAGVDIVLNATPGAVAGWLLGLDGVAILGL 121 A IGV+LLLL LGLE+SA+E ++L+ PS VD VLNA PG V +LG VA + L Sbjct 63 AEIGVILLLLLLGLEYSASELVTNLKKQYPSGIVDFVLNALPGFVCALILGWGLVAAVAL 122 Query 122 AGVTYISSSGVIARLLEDLRRLGNRETPAVLSVLVLEDFAMAAYLP----LFAVLATDGS 177 AGVT+ISSSGVIA++L DL RLGNRETP +L VLV+ED AMA YLP L A L+ G+ Sbjct 123 AGVTWISSSGVIAKVLGDLGRLGNRETPVILGVLVIEDLAMAIYLPILTALLAGLSLGGA 182 Query 178 WLEAVVGM-TVAIAALLGAFAASYRWGHHVGRLVTHPDSEQLLLRVLGITLIVAAVAESL 236 L V+ + TV + L + R G + R V+ + E LLL VLG+T++VA VA L Sbjct 183 SLTLVISLGTVGLVLYL-----ALRHGRLISRAVSSDNPEMLLLVVLGLTVLVAGVAAEL 237 Query 237 HASAAVGAFLVGLTLTGETADRARMVLTPLRDLFATIFFLGIGLSVDPGKLVSMLPVALA 296 SAAVGAFLVG+ L+GE A+ A +L PLRDLFA +FF+ GLS +P + + AL Sbjct 238 QVSAAVGAFLVGIALSGEVAEGAHNLLAPLRDLFAAVFFVFFGLSTNPADIPPVFLTALL 297 Query 297 LAAVTAATKVATGMFAARREGVARRGQLRAGTALVARGEFSLIIIGLAGASIPGVAALAT 356 LA VT TK+ATG +AARR GV R G+ RAG LVARGEFS++I GLA + P + LAT Sbjct 298 LAVVTVLTKIATGWYAARRAGVQRAGRWRAGGTLVARGEFSIVIAGLAVGTAPEIGPLAT 357 Query 357 AYVFVMAIVGPILARYT 373 AYV ++ I+GP+ AR+T Sbjct 358 AYVLILVILGPLTARWT 374 >gi|331694697|ref|YP_004330936.1| sodium/hydrogen exchanger [Pseudonocardia dioxanivorans CB1190] gi|326949386|gb|AEA23083.1| sodium/hydrogen exchanger [Pseudonocardia dioxanivorans CB1190] Length=434 Score = 284 bits (727), Expect = 2e-74, Method: Compositional matrix adjust. Identities = 175/368 (48%), Positives = 245/368 (67%), Gaps = 3/368 (0%) Query 8 LFELGVLLAVLAVLGAVARRFALSPIPVYLLAGLSLGNGGILGVAAAGEFIATGAPIGVV 67 L ELG + L +LG +A R LSPIP+YLL GL+ G GG++ + GEF + +GVV Sbjct 8 LLELGAIFFGLGLLGRLAHRIGLSPIPLYLLGGLAFGQGGLVPLGDIGEFTSLAGEVGVV 67 Query 68 LLLLALGLEFSATEFASSLRHHLPSAGVDIVLNATPGAVAGWLLGLDGVAILGLAGVTYI 127 LLLL LGLE+SA+E + +R + +DIVLNA PG LLG V + + GVTYI Sbjct 68 LLLLLLGLEYSASELITGMRRSWTAGVLDIVLNAAPGVAVALLLGWGPVGAIVMGGVTYI 127 Query 128 SSSGVIARLLEDLRRLGNRETPAVLSVLVLEDFAMAAYLPLFAVLATDGSWLEAVVGMTV 187 SSSG++A++L +L R+GNRETP VLS+LV ED MA YLP+ + S+L + + + Sbjct 128 SSSGIVAKVLAELGRIGNRETPVVLSILVFEDLVMALYLPILTAILAGVSFLGGLTAVGI 187 Query 188 AIAALLGAFAASYRWGHHVGRLVTHPDSEQLLLRVLGITLIVAAVAESLHASAAVGAFLV 247 ++ + + R+G V +V PD E LL+VLG L+VA A ++ SAAVGAFL+ Sbjct 188 SLLVITVVLVVALRYGRFVSAIVDSPDREVFLLKVLGAALLVAGFASAMQVSAAVGAFLL 247 Query 248 GLTLTGETADRARMVLTPLRDLFATIFFLGIGLSVDPGKLVSMLPVALALAAVTAATKVA 307 G+ ++G TA+ A +L PLRDLFA +FF+ GL+ DP + +L A+ALA VT TK+ Sbjct 248 GIAISGSTAENATKLLEPLRDLFAAVFFVVFGLNTDPRSIPPVLGFAVALAVVTTLTKIG 307 Query 308 TGMFAARREGVARRGQLRAGTALVARGEFSLIIIGLA--GASIPG-VAALATAYVFVMAI 364 TG +AA+R+G+ + G+ RAG ALVARGEFS++I GLA A++P +AAL T+YV +MA+ Sbjct 308 TGWWAAQRQGIGKLGRARAGAALVARGEFSIVIAGLAVGYAAVPADLAALTTSYVLIMAV 367 Query 365 VGPILARY 372 +GPI+ RY Sbjct 368 MGPIVTRY 375 >gi|324998145|ref|ZP_08119257.1| monovalent cation:H+ antiporter-2, CPA2 family protein [Pseudonocardia sp. P1] Length=395 Score = 284 bits (726), Expect = 2e-74, Method: Compositional matrix adjust. Identities = 179/368 (49%), Positives = 243/368 (67%), Gaps = 3/368 (0%) Query 8 LFELGVLLAVLAVLGAVARRFALSPIPVYLLAGLSLGNGGILGVAAAGEFIATGAPIGVV 67 L ELG + L +LG +A++ LSPIP+YL+ GL+ G+GGI + G+F + +GVV Sbjct 8 LLELGAVFFGLGLLGRLAQKIGLSPIPLYLVGGLAFGSGGIFPLGDIGDFTSLAGEVGVV 67 Query 68 LLLLALGLEFSATEFASSLRHHLPSAGVDIVLNATPGAVAGWLLGLDGVAILGLAGVTYI 127 LLLL LGLE+SA E + L+ + VDIVLNA PG +LG V + L GVTYI Sbjct 68 LLLLLLGLEYSAAELVTGLKRSWTAGLVDIVLNAAPGVAVALILGWGPVGAMVLGGVTYI 127 Query 128 SSSGVIARLLEDLRRLGNRETPAVLSVLVLEDFAMAAYLPLFAVLATDGSWLEAVVGMTV 187 SSSG++A++L DL RLGNRETP +LSVLV ED MA YLP+ L + + +T+ Sbjct 128 SSSGIVAKVLSDLGRLGNRETPVILSVLVFEDLVMALYLPILTALLLGVTLWGGISAVTI 187 Query 188 AIAALLGAFAASYRWGHHVGRLVTHPDSEQLLLRVLGITLIVAAVAESLHASAAVGAFLV 247 ++ + + R+G +V +V D E LL+VLG L+VA A+++ SAAVGAFL+ Sbjct 188 SLVVIAVVLVVALRYGRYVSAIVDSDDREVFLLKVLGAALLVAGFAQAMQVSAAVGAFLL 247 Query 248 GLTLTGETADRARMVLTPLRDLFATIFFLGIGLSVDPGKLVSMLPVALALAAVTAATKVA 307 G+ ++G TA+ A +L PLRDLFA +FF+ GL+ DP + +L AL LA T ATK A Sbjct 248 GIAISGSTAENATKLLEPLRDLFAAVFFVVFGLTTDPRAIPPVLGWALVLAVSTTATKYA 307 Query 308 TGMFAARREGVARRGQLRAGTALVARGEFSLIIIGLA--GASIPG-VAALATAYVFVMAI 364 TG +AARR + R G+ RAG ALVARGEFS++I GLA A++P ++ALATAYV +MA+ Sbjct 308 TGWWAARRARIGRMGRARAGAALVARGEFSIVIAGLAVGYAAVPAELSALATAYVLIMAV 367 Query 365 VGPILARY 372 +GPI ARY Sbjct 368 LGPIAARY 375 >gi|325965052|ref|YP_004242958.1| Kef-type K+ transporter, membrane component [Arthrobacter phenanthrenivorans Sphe3] gi|323471139|gb|ADX74824.1| Kef-type K+ transport system, membrane component [Arthrobacter phenanthrenivorans Sphe3] Length=392 Score = 282 bits (722), Expect = 7e-74, Method: Compositional matrix adjust. Identities = 185/370 (50%), Positives = 250/370 (68%), Gaps = 3/370 (0%) Query 8 LFELGVLLAVLAVLGAVARRFALSPIPVYLLAGLSLGNGGILGVAAAGEFIATGAPIGVV 67 L ELG ++ L +L +A R +SPIP+YLL GL+ G GGI+ + EF IGV+ Sbjct 8 LIELGAVVFCLGLLARLAGRVGMSPIPLYLLGGLAFGAGGIVKLEGMKEFAHVSGEIGVI 67 Query 68 LLLLALGLEFSATEFASSLRHHLPSAGVDIVLNATPGAVAGWLLGLDGVAILGLAGVTYI 127 LLLL LGLE++A E + LR + +D+VLN PGA +LLG GV + + GVTYI Sbjct 68 LLLLMLGLEYTAAELFTGLRRSWQAGILDLVLNFLPGAALAYLLGWGGVGAMVMGGVTYI 127 Query 128 SSSGVIARLLEDLRRLGNRETPAVLSVLVLEDFAMAAYLPLFAVLATDGSWLEAVVGMTV 187 SSSG+ A+++ DL R+GNRETP VLS+LV ED AMA YLP+ + S+L + + + Sbjct 128 SSSGIAAKVITDLGRIGNRETPVVLSILVFEDLAMAVYLPVLTTILAGVSFLGGLTSVGI 187 Query 188 AIAALLGAFAASYRWGHHVGRLVTHPDSEQLLLRVLGITLIVAAVAESLHASAAVGAFLV 247 A+A + + R GHHV + V +SE LL VLG L+VA VA ++ SAAVGAFL+ Sbjct 188 ALAVVSVVLMVALRHGHHVSKAVHSENSEVFLLNVLGAALLVAGVASAMQVSAAVGAFLL 247 Query 248 GLTLTGETADRARMVLTPLRDLFATIFFLGIGLSVDPGKLVSMLPVALALAAVTAATKVA 307 G+ ++G TA A +L PLRDLFA IFF+ GL+ DP + +L AL LA +TAATK+A Sbjct 248 GIAISGATAHNATRILEPLRDLFAAIFFVAFGLNTDPSSIPPVLGWALVLAVITAATKMA 307 Query 308 TGMFAARREGVARRGQLRAGTALVARGEFSLIIIGLAGAS--IPG-VAALATAYVFVMAI 364 TG++AA++ G+AR G+ RAG L+ARGEFS++I GLA AS +PG +AALATAYV VMA+ Sbjct 308 TGIWAAKQAGIARPGRFRAGATLIARGEFSIVIAGLAVASGAVPGELAALATAYVLVMAV 367 Query 365 VGPILARYTG 374 +GP+ AR+ G Sbjct 368 LGPLAARFAG 377 >gi|288917341|ref|ZP_06411708.1| sodium/hydrogen exchanger [Frankia sp. EUN1f] gi|288351206|gb|EFC85416.1| sodium/hydrogen exchanger [Frankia sp. EUN1f] Length=404 Score = 281 bits (720), Expect = 1e-73, Method: Compositional matrix adjust. Identities = 191/373 (52%), Positives = 249/373 (67%), Gaps = 10/373 (2%) Query 8 LFELGVLLAVLAVLGAVARRFALSPIPVYLLAGLSLGNGGILGVAAAGEFIATGAPIGVV 67 ELG +L VL VLG +A RF++SPIP+YL+AGL+ G+GG+L + A+ EFI GA +GV+ Sbjct 8 FLELGAVLFVLGVLGHLASRFSISPIPLYLVAGLAFGHGGLLPLGASEEFIEIGAELGVI 67 Query 68 LLLLALGLEFSATEFASSLRHHLPSAGVDIVLNATPGAVAGWLLGLDGVAILGLAGVTYI 127 LLLL LGLE++A E LR + +D+ +NA PG VA ++LG +A + + GVT I Sbjct 68 LLLLTLGLEYTAEELLYGLRRQASAGVLDLTVNAVPGVVAAFVLGWGPLAAVVMGGVTAI 127 Query 128 SSSGVIARLLEDLRRLGNRETPAVLSVLVLEDFAMAAYLPLFAVLATDGSWLEAVVGMTV 187 SSSG+IA++L DL R+GNRETP VLSVLVLED AMAAYLP+ L + + + V Sbjct 128 SSSGIIAKVLGDLGRIGNRETPVVLSVLVLEDLAMAAYLPVLTALLAHHTLARGSLTVAV 187 Query 188 AIAALLGAFAASYRWGHHVGRLV----THPDSEQLLLRVLGITLIVAAVAESLHASAAVG 243 A+ AL+ + R V LV + + E LLLR LG+T+ VA VA+ + SAAVG Sbjct 188 ALGALVAVLYIALRHSEKVTLLVYSARSDRNDEVLLLRSLGLTMFVAGVAQRMQVSAAVG 247 Query 244 AFLVGLTLTGETADRARMVLTPLRDLFATIFFLGIGLSVDPGKLVSMLPVALALAAVTAA 303 AFLVG+ L+G A+ AR VLTPLRDLFA +FF+ GL DP + S LP A LA Sbjct 248 AFLVGIALSGPVAEGAREVLTPLRDLFAAVFFVFFGLQTDPAHIPSALPAASLLAVSGVI 307 Query 304 TKVATGMFAARREGVARRGQLRAGTALVARGEFSLIIIGLAGASIPGVAA----LATAYV 359 TKVATG +AARR G+A G+ RAG ALVARGEFS++I GL A + GV A LA YV Sbjct 308 TKVATGWWAARRAGIASMGRYRAGAALVARGEFSIVIAGL--AVVAGVNAKLGPLAACYV 365 Query 360 FVMAIVGPILARY 372 +MA++GP+ AR+ Sbjct 366 LLMAVLGPLAARF 378 >gi|297155915|gb|ADI05627.1| putative transmembrane transport protein [Streptomyces bingchenggensis BCW-1] Length=423 Score = 281 bits (718), Expect = 2e-73, Method: Compositional matrix adjust. Identities = 189/348 (55%), Positives = 244/348 (71%), Gaps = 2/348 (0%) Query 28 FALSPIPVYLLAGLSLGNGGILGVAAAGEFIATGAPIGVVLLLLALGLEFSATEFASSLR 87 F SPIP+YLLAGL+ G GG+L + A+ EF+A GA IGV+LLLL LGLE++A++ S+L+ Sbjct 28 FQFSPIPLYLLAGLAFGEGGLLPLGASEEFVAIGAEIGVILLLLMLGLEYTASDLVSNLK 87 Query 88 HHLPSAGVDIVLNATPGAVAGWLLGLDGVAILGLAGVTYISSSGVIARLLEDLRRLGNRE 147 P+ VD LNA PGAV LLG VA + LAGVT+ISSSGVIA++L DL RLGNRE Sbjct 88 TQYPAGLVDAALNALPGAVMALLLGWGPVAAVVLAGVTWISSSGVIAKVLGDLGRLGNRE 147 Query 148 TPAVLSVLVLEDFAMAAYLPLFAVLATDGSWLEAVVGMTVAIAALLGAFAASYRWGHHVG 207 TP +LS+LVLED AMA YLP+ L S + + +A+ + R+G + Sbjct 148 TPVILSILVLEDLAMAVYLPIITALLAGVSLAAGSITLAIALGVAGLVLFLAVRYGRLIS 207 Query 208 RLVTHPDSEQLLLRVLGITLIVAAVAESLHASAAVGAFLVGLTLTGETADRARMVLTPLR 267 R V+ D E+LLL VLG+TL+VA +A+ L SAAVGAFLVG+ L+GE A+ A +L+PLR Sbjct 208 RFVSSDDPEKLLLVVLGLTLLVAGIAQQLQVSAAVGAFLVGIALSGEVAEGAHNLLSPLR 267 Query 268 DLFATIFFLGIGLSVDPGKLVSMLPVALALAAVTAATKVATGMFAARREGVARRGQLRAG 327 DLFA +FF+ GL DP + +L ALALA VTA TKVATG +AA+R G++ +G+ RAG Sbjct 268 DLFAAVFFVFFGLHTDPASIPPVLLPALALATVTACTKVATGYWAAKRAGISVKGRWRAG 327 Query 328 TALVARGEFSLIIIGLA-GASI-PGVAALATAYVFVMAIVGPILARYT 373 LVARGEFS++I GLA A I P + LATAYV ++ I+GPI ARYT Sbjct 328 GTLVARGEFSIVIAGLAVTAGIEPELGPLATAYVLILVILGPITARYT 375 >gi|295840290|ref|ZP_06827223.1| Na+/H+ exchanger family protein [Streptomyces sp. SPB74] gi|295827896|gb|EFG65692.1| Na+/H+ exchanger family protein [Streptomyces sp. SPB74] Length=387 Score = 280 bits (717), Expect = 2e-73, Method: Compositional matrix adjust. Identities = 200/377 (54%), Positives = 257/377 (69%), Gaps = 10/377 (2%) Query 2 EVSRALLFELGVLLAVLAVLGAVARRFALSPIPVYLLAGLSLGNGGILGVAAAGEFIATG 61 + + LL ELG ++ L +LG +A R SPIP+YLLAGL+ G GG L + A+ EF+ATG Sbjct 3 DTTTELLIELGAIILGLGILGRLAGRIGFSPIPLYLLAGLAFGKGGFLPLDASEEFVATG 62 Query 62 APIGVVLLLLALGLEFSATEFASSLRHHLPSAGVDIVLNATPGAVAGWLLGLDGVAILGL 121 A IGV+LLLL LGLE+SA+E ++L+ PS VD VLNA PG V +LG VA + L Sbjct 63 AEIGVILLLLLLGLEYSASELVTNLKKQYPSGIVDFVLNALPGFVCALILGWGLVAAVAL 122 Query 122 AGVTYISSSGVIARLLEDLRRLGNRETPAVLSVLVLEDFAMAAYLP----LFAVLATDGS 177 AGVT+ISSSGVIA++L DL RLGNRETP +L VLV+ED AMA YLP L A L+ G+ Sbjct 123 AGVTWISSSGVIAKVLGDLGRLGNRETPVILGVLVIEDLAMAVYLPILTALLAGLSIGGA 182 Query 178 WLEAVVGM-TVAIAALLGAFAASYRWGHHVGRLVTHPDSEQLLLRVLGITLIVAAVAESL 236 L V+ + TV + L + R G + R V+ + E LLL VLG+T++VA VA L Sbjct 183 SLTLVISLGTVGLVLYL-----ALRHGRLISRAVSSDNPEMLLLVVLGLTVLVAGVAAEL 237 Query 237 HASAAVGAFLVGLTLTGETADRARMVLTPLRDLFATIFFLGIGLSVDPGKLVSMLPVALA 296 SAAVGAFLVG+ L+GE A+ A +L PLRDLFA +FF+ GLS +P + + AL Sbjct 238 QVSAAVGAFLVGIALSGEVAEGAHNLLAPLRDLFAAVFFVFFGLSTNPADIPPVFLTALL 297 Query 297 LAAVTAATKVATGMFAARREGVARRGQLRAGTALVARGEFSLIIIGLAGASIPGVAALAT 356 LA VT TK+ATG +AARR GV R G+ RAG LVARGEFS++I GLA A+ P + LAT Sbjct 298 LALVTVLTKIATGWYAARRAGVKRAGRWRAGGTLVARGEFSIVIAGLAVATAPEIGPLAT 357 Query 357 AYVFVMAIVGPILARYT 373 AYV ++ I+GP+ AR+T Sbjct 358 AYVLILVILGPLTARWT 374 >gi|290956791|ref|YP_003487973.1| sodium/hydrogen exchange ABC transporter [Streptomyces scabiei 87.22] gi|260646317|emb|CBG69412.1| putative sodium/hydrogen exchange transmembrane transporter [Streptomyces scabiei 87.22] Length=414 Score = 280 bits (715), Expect = 4e-73, Method: Compositional matrix adjust. Identities = 199/370 (54%), Positives = 257/370 (70%), Gaps = 0/370 (0%) Query 4 SRALLFELGVLLAVLAVLGAVARRFALSPIPVYLLAGLSLGNGGILGVAAAGEFIATGAP 63 + A+L ELG ++ L +LG +A R SPIP+YLLAGL+ G GGIL + A+ EF+ATGA Sbjct 4 TTAMLVELGAIILALGLLGRLAGRVGFSPIPLYLLAGLAFGQGGILPLQASEEFVATGAE 63 Query 64 IGVVLLLLALGLEFSATEFASSLRHHLPSAGVDIVLNATPGAVAGWLLGLDGVAILGLAG 123 IGV+LLLL LGLE+SA+E ++L+ PS VD VLNA PGA LLG VA + LAG Sbjct 64 IGVILLLLLLGLEYSASELVTNLKTQYPSGAVDFVLNAAPGAAMALLLGWGPVAAVALAG 123 Query 124 VTYISSSGVIARLLEDLRRLGNRETPAVLSVLVLEDFAMAAYLPLFAVLATDGSWLEAVV 183 VT+ISSSGVIA++L DLRRLGNRETP VL VLVLED +MA YLP+ L S + Sbjct 124 VTWISSSGVIAKVLGDLRRLGNRETPVVLGVLVLEDLSMAVYLPILTALLAGVSLAGGAL 183 Query 184 GMTVAIAALLGAFAASYRWGHHVGRLVTHPDSEQLLLRVLGITLIVAAVAESLHASAAVG 243 + +A+ + + R G + R V+ +E LLL VLG+TL+VA VA+ L SAAVG Sbjct 184 TLLIALGTVGAVLYVALRHGRLISRAVSSESAEMLLLVVLGLTLVVAGVAQHLQVSAAVG 243 Query 244 AFLVGLTLTGETADRARMVLTPLRDLFATIFFLGIGLSVDPGKLVSMLPVALALAAVTAA 303 AFLVG+ L+GE A+ A +L+PLRDLFA +FF+ GL DP + +L ALALAAVT Sbjct 244 AFLVGIALSGEVAEGASSILSPLRDLFAAVFFVFFGLHTDPAAIPPVLLPALALAAVTTL 303 Query 304 TKVATGMFAARREGVARRGQLRAGTALVARGEFSLIIIGLAGASIPGVAALATAYVFVMA 363 TK+ATG +AARR G++ +G+ RAG LVARGEFS++I GLA P V LATAYV ++ Sbjct 304 TKIATGYWAARRAGISAKGRWRAGGTLVARGEFSIVIAGLAVGVEPRVGPLATAYVLILV 363 Query 364 IVGPILARYT 373 ++GP+ AR+T Sbjct 364 VLGPLTARWT 373 Lambda K H 0.325 0.139 0.394 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 749688914200 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40