BLASTP 2.2.25+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.



Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
           15,229,318 sequences; 5,219,829,388 total letters



Query= Rv3246c

Length=228
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

gi|15610382|ref|NP_217763.1|  two component sensory transduction ...   452    2e-125
gi|15842835|ref|NP_337872.1|  DNA-binding response regulator MtrA...   451    3e-125
gi|306790486|ref|ZP_07428808.1|  two component system transcripti...   451    3e-125
gi|41409458|ref|NP_962294.1|  hypothetical protein MAP3360c [Myco...   451    4e-125
gi|240172611|ref|ZP_04751270.1|  DNA-binding response regulator M...   450    8e-125
gi|118618059|ref|YP_906391.1|  two component sensory transduction...   449    2e-124
gi|15827334|ref|NP_301597.1|  two-component response regulator [M...   446    2e-123
gi|254776645|ref|ZP_05218161.1|  DNA-binding response regulator M...   446    2e-123
gi|183981321|ref|YP_001849612.1|  two-component sensory transduct...   444    5e-123
gi|15866137|gb|AAL10207.1|AF410884_3  MtrA [Mycobacterium avium s...   444    6e-123
gi|29336923|sp|Q9CCJ2.2|MTRA_MYCLE  RecName: Full=DNA-binding res...   442    2e-122
gi|169630671|ref|YP_001704320.1|  DNA-binding response regulator ...   430    8e-119
gi|120402752|ref|YP_952581.1|  two component transcriptional regu...   417    6e-115
gi|145225290|ref|YP_001135968.1|  two component transcriptional r...   417    8e-115
gi|118467592|ref|YP_886240.1|  DNA-binding response regulator Mtr...   417    9e-115
gi|108798318|ref|YP_638515.1|  two component transcriptional regu...   414    6e-114
gi|333991626|ref|YP_004524240.1|  two-component sensory transduct...   410    5e-113
gi|326383263|ref|ZP_08204951.1|  response regulator receiver [Gor...   395    2e-108
gi|54026584|ref|YP_120826.1|  putative two-component system respo...   383    1e-104
gi|109158123|pdb|2GWR|A  Chain A, Crystal Structure Of The Respon...   383    1e-104
gi|262203510|ref|YP_003274718.1|  response regulator receiver [Go...   382    2e-104
gi|333921449|ref|YP_004495030.1|  DNA-binding response regulator ...   381    4e-104
gi|111023287|ref|YP_706259.1|  response regulator, two-component ...   380    6e-104
gi|226305655|ref|YP_002765615.1|  two-component response regulato...   379    3e-103
gi|256380300|ref|YP_003103960.1|  winged helix family two compone...   377    9e-103
gi|312140675|ref|YP_004008011.1|  two component system response r...   376    2e-102
gi|319949856|ref|ZP_08023868.1|  DNA-binding response regulator M...   369    2e-100
gi|331698935|ref|YP_004335174.1|  winged helix family two compone...   368    4e-100
gi|296138804|ref|YP_003646047.1|  winged helix family two compone...   365    4e-99 
gi|302530020|ref|ZP_07282362.1|  phosphate regulon transcriptiona...   361    6e-98 
gi|340531476|gb|AEK46681.1|  two component transcriptional regula...   360    7e-98 
gi|300789808|ref|YP_003770099.1|  two-component system response r...   360    9e-98 
gi|257057064|ref|YP_003134896.1|  response regulator with CheY-li...   359    2e-97 
gi|325002114|ref|ZP_08123226.1|  two-component response regulator...   359    2e-97 
gi|134102881|ref|YP_001108542.1|  two-component response regulato...   358    2e-97 
gi|296394611|ref|YP_003659495.1|  transcriptional regulator [Segn...   354    5e-96 
gi|317508033|ref|ZP_07965722.1|  response regulator receiver doma...   352    2e-95 
gi|302560333|ref|ZP_07312675.1|  DNA-binding response regulator [...   350    9e-95 
gi|291439275|ref|ZP_06578665.1|  two-component system response re...   350    9e-95 
gi|10281108|gb|AAG15433.1|AF189161_1  putative response regulator...   350    1e-94 
gi|254392878|ref|ZP_05008047.1|  two-component system response re...   349    1e-94 
gi|21221456|ref|NP_627235.1|  two-component system response regul...   349    1e-94 
gi|294629682|ref|ZP_06708242.1|  DNA-binding response regulator [...   349    2e-94 
gi|302551833|ref|ZP_07304175.1|  phosphate regulon transcriptiona...   349    2e-94 
gi|291445133|ref|ZP_06584523.1|  two-component system response re...   349    2e-94 
gi|302534786|ref|ZP_07287128.1|  phosphate regulon transcriptiona...   349    2e-94 
gi|297194039|ref|ZP_06911437.1|  two-component system response re...   349    2e-94 
gi|182438316|ref|YP_001826035.1|  putative two-component system r...   349    2e-94 
gi|291009674|ref|ZP_06567647.1|  two-component response regulator...   349    2e-94 
gi|294812933|ref|ZP_06771576.1|  Two-component system response re...   348    3e-94 


>gi|15610382|ref|NP_217763.1| two component sensory transduction transcriptional regulatory 
protein MTRA [Mycobacterium tuberculosis H37Rv]
 gi|31794426|ref|NP_856919.1| two component sensory transduction transcriptional regulatory 
protein MTRA [Mycobacterium bovis AF2122/97]
 gi|121639135|ref|YP_979359.1| two component sensory transduction transcriptional regulatory 
protein mtrA [Mycobacterium bovis BCG str. Pasteur 1173P2]
 72 more sequence titles
 Length=228

 Score =  452 bits (1162),  Expect = 2e-125, Method: Compositional matrix adjust.
 Identities = 228/228 (100%), Positives = 228/228 (100%), Gaps = 0/228 (0%)

Query  1    MDTMRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLP  60
            MDTMRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLP
Sbjct  1    MDTMRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLP  60

Query  61   GMNGIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARL  120
            GMNGIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARL
Sbjct  61   GMNGIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARL  120

Query  121  RRNDDEPAEMLSIADVEIDVPAHKVTRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLE  180
            RRNDDEPAEMLSIADVEIDVPAHKVTRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLE
Sbjct  121  RRNDDEPAEMLSIADVEIDVPAHKVTRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLE  180

Query  181  QVWGYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP  228
            QVWGYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP
Sbjct  181  QVWGYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP  228


>gi|15842835|ref|NP_337872.1| DNA-binding response regulator MtrA [Mycobacterium tuberculosis 
CDC1551]
 gi|13883164|gb|AAK47686.1| DNA-binding response regulator MtrA [Mycobacterium tuberculosis 
CDC1551]
Length=235

 Score =  451 bits (1161),  Expect = 3e-125, Method: Compositional matrix adjust.
 Identities = 228/228 (100%), Positives = 228/228 (100%), Gaps = 0/228 (0%)

Query  1    MDTMRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLP  60
            MDTMRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLP
Sbjct  8    MDTMRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLP  67

Query  61   GMNGIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARL  120
            GMNGIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARL
Sbjct  68   GMNGIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARL  127

Query  121  RRNDDEPAEMLSIADVEIDVPAHKVTRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLE  180
            RRNDDEPAEMLSIADVEIDVPAHKVTRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLE
Sbjct  128  RRNDDEPAEMLSIADVEIDVPAHKVTRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLE  187

Query  181  QVWGYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP  228
            QVWGYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP
Sbjct  188  QVWGYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP  235


>gi|306790486|ref|ZP_07428808.1| two component system transcriptional regulator mtrA [Mycobacterium 
tuberculosis SUMu004]
 gi|308333099|gb|EFP21950.1| two component system transcriptional regulator mtrA [Mycobacterium 
tuberculosis SUMu004]
Length=228

 Score =  451 bits (1160),  Expect = 3e-125, Method: Compositional matrix adjust.
 Identities = 227/228 (99%), Positives = 228/228 (100%), Gaps = 0/228 (0%)

Query  1    MDTMRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLP  60
            M+TMRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLP
Sbjct  1    MNTMRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLP  60

Query  61   GMNGIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARL  120
            GMNGIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARL
Sbjct  61   GMNGIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARL  120

Query  121  RRNDDEPAEMLSIADVEIDVPAHKVTRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLE  180
            RRNDDEPAEMLSIADVEIDVPAHKVTRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLE
Sbjct  121  RRNDDEPAEMLSIADVEIDVPAHKVTRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLE  180

Query  181  QVWGYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP  228
            QVWGYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP
Sbjct  181  QVWGYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP  228


>gi|41409458|ref|NP_962294.1| hypothetical protein MAP3360c [Mycobacterium avium subsp. paratuberculosis 
K-10]
 gi|118464131|ref|YP_883351.1| DNA-binding response regulator MtrA [Mycobacterium avium 104]
 gi|254822993|ref|ZP_05227994.1| DNA-binding response regulator MtrA [Mycobacterium intracellulare 
ATCC 13950]
 6 more sequence titles
 Length=228

 Score =  451 bits (1160),  Expect = 4e-125, Method: Compositional matrix adjust.
 Identities = 227/228 (99%), Positives = 228/228 (100%), Gaps = 0/228 (0%)

Query  1    MDTMRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLP  60
            MD+MRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLP
Sbjct  1    MDSMRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLP  60

Query  61   GMNGIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARL  120
            GMNGIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARL
Sbjct  61   GMNGIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARL  120

Query  121  RRNDDEPAEMLSIADVEIDVPAHKVTRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLE  180
            RRNDDEPAEMLSIADVEIDVPAHKVTRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLE
Sbjct  121  RRNDDEPAEMLSIADVEIDVPAHKVTRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLE  180

Query  181  QVWGYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP  228
            QVWGYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP
Sbjct  181  QVWGYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP  228


>gi|240172611|ref|ZP_04751270.1| DNA-binding response regulator MtrA [Mycobacterium kansasii ATCC 
12478]
Length=228

 Score =  450 bits (1157),  Expect = 8e-125, Method: Compositional matrix adjust.
 Identities = 227/228 (99%), Positives = 228/228 (100%), Gaps = 0/228 (0%)

Query  1    MDTMRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLP  60
            MDTMRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLP
Sbjct  1    MDTMRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLP  60

Query  61   GMNGIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARL  120
            GMNGIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARL
Sbjct  61   GMNGIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARL  120

Query  121  RRNDDEPAEMLSIADVEIDVPAHKVTRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLE  180
            RRNDDEPAEMLSIADV+IDVPAHKVTRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLE
Sbjct  121  RRNDDEPAEMLSIADVDIDVPAHKVTRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLE  180

Query  181  QVWGYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP  228
            QVWGYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP
Sbjct  181  QVWGYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP  228


>gi|118618059|ref|YP_906391.1| two component sensory transduction transcriptional regulatory 
protein MtrA [Mycobacterium ulcerans Agy99]
 gi|118570169|gb|ABL04920.1| two component sensory transduction transcriptional regulatory 
protein MtrA [Mycobacterium ulcerans Agy99]
Length=228

 Score =  449 bits (1154),  Expect = 2e-124, Method: Compositional matrix adjust.
 Identities = 226/228 (99%), Positives = 227/228 (99%), Gaps = 0/228 (0%)

Query  1    MDTMRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLP  60
            MDTMRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLP
Sbjct  1    MDTMRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLP  60

Query  61   GMNGIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARL  120
            GMNGIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARL
Sbjct  61   GMNGIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARL  120

Query  121  RRNDDEPAEMLSIADVEIDVPAHKVTRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLE  180
            RRNDDEPAEMLSIADV+IDVPAHK TRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLE
Sbjct  121  RRNDDEPAEMLSIADVDIDVPAHKATRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLE  180

Query  181  QVWGYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP  228
            QVWGYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP
Sbjct  181  QVWGYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP  228


>gi|15827334|ref|NP_301597.1| two-component response regulator [Mycobacterium leprae TN]
 gi|221229812|ref|YP_002503228.1| putative two-component response regulator [Mycobacterium leprae 
Br4923]
 gi|13092883|emb|CAC30282.1| putative two-component response regulator [Mycobacterium leprae]
 gi|219932919|emb|CAR70867.1| putative two-component response regulator [Mycobacterium leprae 
Br4923]
Length=228

 Score =  446 bits (1146),  Expect = 2e-123, Method: Compositional matrix adjust.
 Identities = 225/228 (99%), Positives = 226/228 (99%), Gaps = 0/228 (0%)

Query  1    MDTMRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLP  60
            MD MRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLP
Sbjct  1    MDIMRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLP  60

Query  61   GMNGIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARL  120
            GMNGIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARL
Sbjct  61   GMNGIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARL  120

Query  121  RRNDDEPAEMLSIADVEIDVPAHKVTRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLE  180
            RRNDDEPAEMLSIADV+IDVPAHKVTRNGE ISLTPLEFDLLVALARKPRQVFTRDVLLE
Sbjct  121  RRNDDEPAEMLSIADVDIDVPAHKVTRNGEHISLTPLEFDLLVALARKPRQVFTRDVLLE  180

Query  181  QVWGYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP  228
            QVWGYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP
Sbjct  181  QVWGYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP  228


>gi|254776645|ref|ZP_05218161.1| DNA-binding response regulator MtrA [Mycobacterium avium subsp. 
avium ATCC 25291]
 gi|45645201|sp|Q93CB8.2|MTRA_MYCPA RecName: Full=DNA-binding response regulator mtrA
 gi|61228246|sp|P0A5Z4.1|MTRA_MYCTU RecName: Full=DNA-binding response regulator mtrA
 gi|61228247|sp|P0A5Z5.1|MTRA_MYCBO RecName: Full=DNA-binding response regulator mtrA
 gi|509815|gb|AAB07804.1| MtrA [Mycobacterium tuberculosis H37Rv]
 gi|336459678|gb|EGO38613.1| response regulator with CheY-like receiver domain, winged-helix 
DNA-binding domain protein [Mycobacterium avium subsp. paratuberculosis 
S397]
Length=225

 Score =  446 bits (1146),  Expect = 2e-123, Method: Compositional matrix adjust.
 Identities = 225/225 (100%), Positives = 225/225 (100%), Gaps = 0/225 (0%)

Query  4    MRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLPGMN  63
            MRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLPGMN
Sbjct  1    MRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLPGMN  60

Query  64   GIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARLRRN  123
            GIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARLRRN
Sbjct  61   GIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARLRRN  120

Query  124  DDEPAEMLSIADVEIDVPAHKVTRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLEQVW  183
            DDEPAEMLSIADVEIDVPAHKVTRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLEQVW
Sbjct  121  DDEPAEMLSIADVEIDVPAHKVTRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLEQVW  180

Query  184  GYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP  228
            GYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP
Sbjct  181  GYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP  225


>gi|183981321|ref|YP_001849612.1| two-component sensory transduction transcriptional regulatory 
protein MtrA [Mycobacterium marinum M]
 gi|183174647|gb|ACC39757.1| two-component sensory transduction transcriptional regulatory 
protein MtrA [Mycobacterium marinum M]
Length=225

 Score =  444 bits (1141),  Expect = 5e-123, Method: Compositional matrix adjust.
 Identities = 224/225 (99%), Positives = 225/225 (100%), Gaps = 0/225 (0%)

Query  4    MRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLPGMN  63
            MRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLPGMN
Sbjct  1    MRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLPGMN  60

Query  64   GIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARLRRN  123
            GIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARLRRN
Sbjct  61   GIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARLRRN  120

Query  124  DDEPAEMLSIADVEIDVPAHKVTRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLEQVW  183
            DDEPAEMLSIADV+IDVPAHKVTRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLEQVW
Sbjct  121  DDEPAEMLSIADVDIDVPAHKVTRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLEQVW  180

Query  184  GYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP  228
            GYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP
Sbjct  181  GYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP  225


>gi|15866137|gb|AAL10207.1|AF410884_3 MtrA [Mycobacterium avium subsp. paratuberculosis]
Length=225

 Score =  444 bits (1141),  Expect = 6e-123, Method: Compositional matrix adjust.
 Identities = 224/224 (100%), Positives = 224/224 (100%), Gaps = 0/224 (0%)

Query  4    MRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLPGMN  63
            MRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLPGMN
Sbjct  1    MRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLPGMN  60

Query  64   GIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARLRRN  123
            GIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARLRRN
Sbjct  61   GIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARLRRN  120

Query  124  DDEPAEMLSIADVEIDVPAHKVTRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLEQVW  183
            DDEPAEMLSIADVEIDVPAHKVTRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLEQVW
Sbjct  121  DDEPAEMLSIADVEIDVPAHKVTRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLEQVW  180

Query  184  GYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGP  227
            GYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGP
Sbjct  181  GYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGP  224


>gi|29336923|sp|Q9CCJ2.2|MTRA_MYCLE RecName: Full=DNA-binding response regulator mtrA
Length=225

 Score =  442 bits (1137),  Expect = 2e-122, Method: Compositional matrix adjust.
 Identities = 223/225 (99%), Positives = 224/225 (99%), Gaps = 0/225 (0%)

Query  4    MRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLPGMN  63
            MRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLPGMN
Sbjct  1    MRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLPGMN  60

Query  64   GIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARLRRN  123
            GIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARLRRN
Sbjct  61   GIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARLRRN  120

Query  124  DDEPAEMLSIADVEIDVPAHKVTRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLEQVW  183
            DDEPAEMLSIADV+IDVPAHKVTRNGE ISLTPLEFDLLVALARKPRQVFTRDVLLEQVW
Sbjct  121  DDEPAEMLSIADVDIDVPAHKVTRNGEHISLTPLEFDLLVALARKPRQVFTRDVLLEQVW  180

Query  184  GYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP  228
            GYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP
Sbjct  181  GYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP  225


>gi|169630671|ref|YP_001704320.1| DNA-binding response regulator MtrA [Mycobacterium abscessus 
ATCC 19977]
 gi|169242638|emb|CAM63666.1| DNA-binding response regulator MtrA [Mycobacterium abscessus]
Length=225

 Score =  430 bits (1105),  Expect = 8e-119, Method: Compositional matrix adjust.
 Identities = 214/225 (96%), Positives = 222/225 (99%), Gaps = 0/225 (0%)

Query  4    MRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLPGMN  63
            MRQRILVVDDDASLAEMLTIVLRGEGF+TAV+ DGTQALTAVRELRPDLVLLDLMLPGMN
Sbjct  1    MRQRILVVDDDASLAEMLTIVLRGEGFETAVVSDGTQALTAVRELRPDLVLLDLMLPGMN  60

Query  64   GIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARLRRN  123
            GIDVCRVLR+DSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVAR+RARLRRN
Sbjct  61   GIDVCRVLRSDSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARIRARLRRN  120

Query  124  DDEPAEMLSIADVEIDVPAHKVTRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLEQVW  183
            DDEPAE+L+IA ++IDVPAHKVTR GEQISLTPLEFDLLVALARKPRQVFTRDVLLEQVW
Sbjct  121  DDEPAELLNIAGIDIDVPAHKVTREGEQISLTPLEFDLLVALARKPRQVFTRDVLLEQVW  180

Query  184  GYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP  228
            GYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP
Sbjct  181  GYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP  225


>gi|120402752|ref|YP_952581.1| two component transcriptional regulator [Mycobacterium vanbaalenii 
PYR-1]
 gi|119955570|gb|ABM12575.1| two component transcriptional regulator, winged helix family 
[Mycobacterium vanbaalenii PYR-1]
Length=228

 Score =  417 bits (1072),  Expect = 6e-115, Method: Compositional matrix adjust.
 Identities = 221/228 (97%), Positives = 225/228 (99%), Gaps = 0/228 (0%)

Query  1    MDTMRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLP  60
            MDTMRQRILVVDDD SLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLP
Sbjct  1    MDTMRQRILVVDDDPSLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLP  60

Query  61   GMNGIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARL  120
            GMNGIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDY+MKPFKPKELVARVRARL
Sbjct  61   GMNGIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYVMKPFKPKELVARVRARL  120

Query  121  RRNDDEPAEMLSIADVEIDVPAHKVTRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLE  180
            RRN+DEPAEMLSIAD++IDVPAHKVTR GEQISLTPLEFDLLVALARKPRQVFTRDVLLE
Sbjct  121  RRNEDEPAEMLSIADIDIDVPAHKVTRQGEQISLTPLEFDLLVALARKPRQVFTRDVLLE  180

Query  181  QVWGYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP  228
            QVWGYRHPADTRLVNVHVQRLRAKVEKDPENP VVLTVRGVGYKAGPP
Sbjct  181  QVWGYRHPADTRLVNVHVQRLRAKVEKDPENPQVVLTVRGVGYKAGPP  228


>gi|145225290|ref|YP_001135968.1| two component transcriptional regulator [Mycobacterium gilvum 
PYR-GCK]
 gi|315445587|ref|YP_004078466.1| response regulator with CheY-like receiver domain and winged-helix 
DNA-binding domain [Mycobacterium sp. Spyr1]
 gi|145217776|gb|ABP47180.1| two component transcriptional regulator, winged helix family 
[Mycobacterium gilvum PYR-GCK]
 gi|315263890|gb|ADU00632.1| response regulator with CheY-like receiver domain and winged-helix 
DNA-binding domain [Mycobacterium sp. Spyr1]
Length=228

 Score =  417 bits (1071),  Expect = 8e-115, Method: Compositional matrix adjust.
 Identities = 221/228 (97%), Positives = 225/228 (99%), Gaps = 0/228 (0%)

Query  1    MDTMRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLP  60
            MD+MRQRILVVDDD SLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLP
Sbjct  1    MDSMRQRILVVDDDPSLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLP  60

Query  61   GMNGIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARL  120
            GMNGIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDY+MKPFKPKELVARVRARL
Sbjct  61   GMNGIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYVMKPFKPKELVARVRARL  120

Query  121  RRNDDEPAEMLSIADVEIDVPAHKVTRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLE  180
            RRN+DEPAEMLSIADV+IDVPAHKVTR GEQISLTPLEFDLLVALARKPRQVFTRDVLLE
Sbjct  121  RRNEDEPAEMLSIADVDIDVPAHKVTRQGEQISLTPLEFDLLVALARKPRQVFTRDVLLE  180

Query  181  QVWGYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP  228
            QVWGYRHPADTRLVNVHVQRLRAKVEKDPENP VVLTVRGVGYKAGPP
Sbjct  181  QVWGYRHPADTRLVNVHVQRLRAKVEKDPENPQVVLTVRGVGYKAGPP  228


>gi|118467592|ref|YP_886240.1| DNA-binding response regulator MtrA [Mycobacterium smegmatis 
str. MC2 155]
 gi|118168879|gb|ABK69775.1| DNA-binding response regulator MtrA [Mycobacterium smegmatis 
str. MC2 155]
Length=228

 Score =  417 bits (1071),  Expect = 9e-115, Method: Compositional matrix adjust.
 Identities = 221/228 (97%), Positives = 224/228 (99%), Gaps = 0/228 (0%)

Query  1    MDTMRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLP  60
            MDTMRQRILVVDDD SLAEMLTIVLRGEGFDTAVIGDG+QALTAVRELRPDLVLLDLMLP
Sbjct  1    MDTMRQRILVVDDDPSLAEMLTIVLRGEGFDTAVIGDGSQALTAVRELRPDLVLLDLMLP  60

Query  61   GMNGIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARL  120
            GMNGIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDY+MKPFKPKELVARVRARL
Sbjct  61   GMNGIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYVMKPFKPKELVARVRARL  120

Query  121  RRNDDEPAEMLSIADVEIDVPAHKVTRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLE  180
            RRN+DEPAEMLSI DVEIDVPAHKVTR GEQISLTPLEFDLLVALARKPRQVFTRDVLLE
Sbjct  121  RRNEDEPAEMLSIGDVEIDVPAHKVTRQGEQISLTPLEFDLLVALARKPRQVFTRDVLLE  180

Query  181  QVWGYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP  228
            QVWGYRHPADTRLVNVHVQRLRAKVEKDPENP VVLTVRGVGYKAGPP
Sbjct  181  QVWGYRHPADTRLVNVHVQRLRAKVEKDPENPQVVLTVRGVGYKAGPP  228


>gi|108798318|ref|YP_638515.1| two component transcriptional regulator [Mycobacterium sp. MCS]
 gi|119867415|ref|YP_937367.1| two component transcriptional regulator [Mycobacterium sp. KMS]
 gi|126433983|ref|YP_001069674.1| two component transcriptional regulator [Mycobacterium sp. JLS]
 gi|108768737|gb|ABG07459.1| two component transcriptional regulator, winged helix family 
[Mycobacterium sp. MCS]
 gi|119693504|gb|ABL90577.1| two component transcriptional regulator, winged helix family 
[Mycobacterium sp. KMS]
 gi|126233783|gb|ABN97183.1| two component transcriptional regulator, winged helix family 
[Mycobacterium sp. JLS]
Length=228

 Score =  414 bits (1063),  Expect = 6e-114, Method: Compositional matrix adjust.
 Identities = 218/228 (96%), Positives = 224/228 (99%), Gaps = 0/228 (0%)

Query  1    MDTMRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLP  60
            MD+MRQRILVVDDD SLAEMLTIVLRGEGFDTAV+GDGTQAL+AVRELRPDLVLLDLMLP
Sbjct  1    MDSMRQRILVVDDDPSLAEMLTIVLRGEGFDTAVVGDGTQALSAVRELRPDLVLLDLMLP  60

Query  61   GMNGIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARL  120
            GMNGIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDY+MKPFKPKELVARVRARL
Sbjct  61   GMNGIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYVMKPFKPKELVARVRARL  120

Query  121  RRNDDEPAEMLSIADVEIDVPAHKVTRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLE  180
            RRN+DEPAE+LSI DVEIDVPAHKVTR GEQISLTPLEFDLLVALARKPRQVFTRDVLLE
Sbjct  121  RRNEDEPAELLSIGDVEIDVPAHKVTRQGEQISLTPLEFDLLVALARKPRQVFTRDVLLE  180

Query  181  QVWGYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP  228
            QVWGYRHPADTRLVNVHVQRLRAKVEKDPENP VVLTVRGVGYKAGPP
Sbjct  181  QVWGYRHPADTRLVNVHVQRLRAKVEKDPENPQVVLTVRGVGYKAGPP  228


>gi|333991626|ref|YP_004524240.1| two-component sensory transduction transcriptional regulatory 
protein MtrA [Mycobacterium sp. JDM601]
 gi|333487594|gb|AEF36986.1| two-component sensory transduction transcriptional regulatory 
protein MtrA [Mycobacterium sp. JDM601]
Length=228

 Score =  410 bits (1055),  Expect = 5e-113, Method: Compositional matrix adjust.
 Identities = 217/228 (96%), Positives = 223/228 (98%), Gaps = 0/228 (0%)

Query  1    MDTMRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLP  60
            M  MRQRILVVDDDASLAEMLTIVLRGEGFDTAV+GDGTQALTAV ELRPDLVLLDLMLP
Sbjct  1    MYAMRQRILVVDDDASLAEMLTIVLRGEGFDTAVVGDGTQALTAVHELRPDLVLLDLMLP  60

Query  61   GMNGIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARL  120
            GMNGIDVCRVLR DSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARL
Sbjct  61   GMNGIDVCRVLRKDSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARL  120

Query  121  RRNDDEPAEMLSIADVEIDVPAHKVTRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLE  180
            RRNDDEPAEMLSIAD++IDVPAHKV+R GEQISLTPLEFDLLVALARKPRQVFTR+VLLE
Sbjct  121  RRNDDEPAEMLSIADIDIDVPAHKVSRGGEQISLTPLEFDLLVALARKPRQVFTREVLLE  180

Query  181  QVWGYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP  228
            QVWGYRHPADTRLVNVHVQRLRAKVE+DPENPTVVLTVRGVGYKAGPP
Sbjct  181  QVWGYRHPADTRLVNVHVQRLRAKVEQDPENPTVVLTVRGVGYKAGPP  228


>gi|326383263|ref|ZP_08204951.1| response regulator receiver [Gordonia neofelifaecis NRRL B-59395]
 gi|326198013|gb|EGD55199.1| response regulator receiver [Gordonia neofelifaecis NRRL B-59395]
Length=225

 Score =  395 bits (1016),  Expect = 2e-108, Method: Compositional matrix adjust.
 Identities = 197/225 (88%), Positives = 214/225 (96%), Gaps = 0/225 (0%)

Query  4    MRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLPGMN  63
            M+ RILVVDDDA+LAEMLTIVL+ EGF+  V+GDGTQALTAVRE+RPDLVLLDLMLPGMN
Sbjct  1    MKPRILVVDDDAALAEMLTIVLKNEGFEPFVVGDGTQALTAVREVRPDLVLLDLMLPGMN  60

Query  64   GIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARLRRN  123
            GIDVCRVLR+DSGVPIVMLTAK+DTVDVVLGLESGADDY++KPFKPKELVAR+RARLRR 
Sbjct  61   GIDVCRVLRSDSGVPIVMLTAKSDTVDVVLGLESGADDYMVKPFKPKELVARIRARLRRT  120

Query  124  DDEPAEMLSIADVEIDVPAHKVTRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLEQVW  183
            +D+PAE+L+I  VEIDVPAHKVTR+G  ISLTPLEFDLLVALARKPRQVFTRDVLLEQVW
Sbjct  121  EDDPAELLAIGPVEIDVPAHKVTRDGVPISLTPLEFDLLVALARKPRQVFTRDVLLEQVW  180

Query  184  GYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP  228
            GYRHPADTRLVNVHVQRLRAKVE DPENP +VLTVRGVGYKAGPP
Sbjct  181  GYRHPADTRLVNVHVQRLRAKVEIDPENPEIVLTVRGVGYKAGPP  225


>gi|54026584|ref|YP_120826.1| putative two-component system response regulator [Nocardia farcinica 
IFM 10152]
 gi|54018092|dbj|BAD59462.1| putative two-component system response regulator [Nocardia farcinica 
IFM 10152]
Length=225

 Score =  383 bits (984),  Expect = 1e-104, Method: Compositional matrix adjust.
 Identities = 202/225 (90%), Positives = 215/225 (96%), Gaps = 0/225 (0%)

Query  4    MRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLPGMN  63
            M+ +ILVVDDD +LAEMLTIVLRGEGFD  V+GDGTQAL AVRE+RPDLVLLDLMLPGMN
Sbjct  1    MKPKILVVDDDMALAEMLTIVLRGEGFDPHVVGDGTQALAAVREIRPDLVLLDLMLPGMN  60

Query  64   GIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARLRRN  123
            GIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYI+KPFKPKELVARVRARLRR 
Sbjct  61   GIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIVKPFKPKELVARVRARLRRT  120

Query  124  DDEPAEMLSIADVEIDVPAHKVTRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLEQVW  183
            ++EPAE+LSIAD+ IDVPAHKVTR G+QISLTPLEFDLLVALARKPRQVFTR+VLLEQVW
Sbjct  121  EEEPAELLSIADIVIDVPAHKVTRGGQQISLTPLEFDLLVALARKPRQVFTREVLLEQVW  180

Query  184  GYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP  228
            GYRH ADTRLVNVHVQRLRAKVEKDPENP +VLTVRGVGYKAGPP
Sbjct  181  GYRHAADTRLVNVHVQRLRAKVEKDPENPEIVLTVRGVGYKAGPP  225


>gi|109158123|pdb|2GWR|A Chain A, Crystal Structure Of The Response Regulator Protein 
Mtra From Mycobacterium Tuberculosis
Length=238

 Score =  383 bits (983),  Expect = 1e-104, Method: Compositional matrix adjust.
 Identities = 220/227 (97%), Positives = 220/227 (97%), Gaps = 0/227 (0%)

Query  2    DTMRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLPG  61
            DT RQRILVVDDDASLAE LTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDL LPG
Sbjct  2    DTXRQRILVVDDDASLAEXLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLXLPG  61

Query  62   MNGIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARLR  121
             NGIDVCRVLRADSGVPIV LTAKTDTVDVVLGLESGADDYI KPFKPKELVARVRARLR
Sbjct  62   XNGIDVCRVLRADSGVPIVXLTAKTDTVDVVLGLESGADDYIXKPFKPKELVARVRARLR  121

Query  122  RNDDEPAEMLSIADVEIDVPAHKVTRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLEQ  181
            RNDDEPAE LSIADVEIDVPAHKVTRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLEQ
Sbjct  122  RNDDEPAEXLSIADVEIDVPAHKVTRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLEQ  181

Query  182  VWGYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP  228
            VWGYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP
Sbjct  182  VWGYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP  228


>gi|262203510|ref|YP_003274718.1| response regulator receiver [Gordonia bronchialis DSM 43247]
 gi|343927671|ref|ZP_08767139.1| two-component response regulator MtrA [Gordonia alkanivorans 
NBRC 16433]
 gi|262086857|gb|ACY22825.1| response regulator receiver [Gordonia bronchialis DSM 43247]
 gi|343762312|dbj|GAA14065.1| two-component response regulator MtrA [Gordonia alkanivorans 
NBRC 16433]
Length=225

 Score =  382 bits (982),  Expect = 2e-104, Method: Compositional matrix adjust.
 Identities = 204/225 (91%), Positives = 215/225 (96%), Gaps = 0/225 (0%)

Query  4    MRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLPGMN  63
            M+ RILVVDDDA+LAEMLTIVLRGEGF+  V+GDGTQALTAVRE+RPDLVLLDLMLPGMN
Sbjct  1    MKPRILVVDDDAALAEMLTIVLRGEGFEPFVVGDGTQALTAVREIRPDLVLLDLMLPGMN  60

Query  64   GIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARLRRN  123
            GIDVCRVLRADSGVPIVMLTAK+DTVDVVLGLESGADDY++KPFKPKELVARVRARLRR 
Sbjct  61   GIDVCRVLRADSGVPIVMLTAKSDTVDVVLGLESGADDYMVKPFKPKELVARVRARLRRT  120

Query  124  DDEPAEMLSIADVEIDVPAHKVTRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLEQVW  183
            D+EPAE+LSI  VEIDVPAHKVTR+G  ISLTPLEFDLLVALARKPRQVFTRDVLLEQVW
Sbjct  121  DEEPAELLSIGPVEIDVPAHKVTRDGVPISLTPLEFDLLVALARKPRQVFTRDVLLEQVW  180

Query  184  GYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP  228
            GYRHPADTRLVNVHVQRLRAKVE DPENP VVLTVRGVGYKAGPP
Sbjct  181  GYRHPADTRLVNVHVQRLRAKVETDPENPEVVLTVRGVGYKAGPP  225


>gi|333921449|ref|YP_004495030.1| DNA-binding response regulator MtrA [Amycolicicoccus subflavus 
DQS3-9A1]
 gi|333483670|gb|AEF42230.1| DNA-binding response regulator MtrA [Amycolicicoccus subflavus 
DQS3-9A1]
Length=227

 Score =  381 bits (979),  Expect = 4e-104, Method: Compositional matrix adjust.
 Identities = 204/226 (91%), Positives = 215/226 (96%), Gaps = 0/226 (0%)

Query  3    TMRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLPGM  62
             M+ +ILVVDDDA+LAEMLTIVLRGEGF+  VIGDGTQAL+AVRE+RPDLVLLDLMLPGM
Sbjct  2    NMKPKILVVDDDAALAEMLTIVLRGEGFEPYVIGDGTQALSAVREIRPDLVLLDLMLPGM  61

Query  63   NGIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARLRR  122
            NGIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDY++KPFKPKELVARVRARLRR
Sbjct  62   NGIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYVIKPFKPKELVARVRARLRR  121

Query  123  NDDEPAEMLSIADVEIDVPAHKVTRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLEQV  182
             DDEPAE+LSI D+EIDVPAHKVTR GEQISLTPLEFDLLVALARKPRQVFTR+VLLEQV
Sbjct  122  RDDEPAELLSIGDIEIDVPAHKVTREGEQISLTPLEFDLLVALARKPRQVFTREVLLEQV  181

Query  183  WGYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP  228
            WGYRH ADTRLVNVHVQRLRAKVE DPE P VVLTVRGVGYKAGPP
Sbjct  182  WGYRHAADTRLVNVHVQRLRAKVENDPEKPEVVLTVRGVGYKAGPP  227


>gi|111023287|ref|YP_706259.1| response regulator, two-component system [Rhodococcus jostii 
RHA1]
 gi|226365794|ref|YP_002783577.1| two-component response regulator MtrA [Rhodococcus opacus B4]
 gi|110822817|gb|ABG98101.1| response regulator, two-component system [Rhodococcus jostii 
RHA1]
 gi|226244284|dbj|BAH54632.1| two-component response regulator MtrA [Rhodococcus opacus B4]
Length=225

 Score =  380 bits (977),  Expect = 6e-104, Method: Compositional matrix adjust.
 Identities = 204/225 (91%), Positives = 212/225 (95%), Gaps = 0/225 (0%)

Query  4    MRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLPGMN  63
            M+ RILVVDDD +LAEMLTIVLRGEGFD  V+GDGTQALTAVRE RPDLVLLDLMLPGMN
Sbjct  1    MKPRILVVDDDTALAEMLTIVLRGEGFDPYVVGDGTQALTAVRETRPDLVLLDLMLPGMN  60

Query  64   GIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARLRRN  123
            GIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARLRR 
Sbjct  61   GIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARLRRT  120

Query  124  DDEPAEMLSIADVEIDVPAHKVTRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLEQVW  183
            +DEPAE+LSIAD+ IDVPAHKV+R  E ISLTPLEFDLLVALARKPRQVFTR+VLLEQVW
Sbjct  121  EDEPAELLSIADIVIDVPAHKVSRGEELISLTPLEFDLLVALARKPRQVFTREVLLEQVW  180

Query  184  GYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP  228
            GYRH ADTRLVNVHVQRLRAKVE DPENP VVLTVRGVGYKAGPP
Sbjct  181  GYRHAADTRLVNVHVQRLRAKVETDPENPEVVLTVRGVGYKAGPP  225


>gi|226305655|ref|YP_002765615.1| two-component response regulator MtrA [Rhodococcus erythropolis 
PR4]
 gi|229489658|ref|ZP_04383521.1| response regulator, two-component system [Rhodococcus erythropolis 
SK121]
 gi|226184772|dbj|BAH32876.1| two-component response regulator MtrA [Rhodococcus erythropolis 
PR4]
 gi|229323755|gb|EEN89513.1| response regulator, two-component system [Rhodococcus erythropolis 
SK121]
Length=225

 Score =  379 bits (972),  Expect = 3e-103, Method: Compositional matrix adjust.
 Identities = 202/225 (90%), Positives = 211/225 (94%), Gaps = 0/225 (0%)

Query  4    MRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLPGMN  63
            M+ RILVVDDD +LAEMLTIVLRGEGFD  V+GDGT AL AVRE RPDLVLLDLMLPGMN
Sbjct  1    MKPRILVVDDDTALAEMLTIVLRGEGFDPYVVGDGTLALAAVRETRPDLVLLDLMLPGMN  60

Query  64   GIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARLRRN  123
            GIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARLRR 
Sbjct  61   GIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARLRRT  120

Query  124  DDEPAEMLSIADVEIDVPAHKVTRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLEQVW  183
            ++EPAE+LSIAD+ IDVPAHKV+R  EQISLTPLEFDLLVALARKPRQVFTR+VLLEQVW
Sbjct  121  EEEPAELLSIADIVIDVPAHKVSRGSEQISLTPLEFDLLVALARKPRQVFTREVLLEQVW  180

Query  184  GYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP  228
            GYRH ADTRLVNVHVQRLRAKVE DPENP VVLTVRGVGYKAGPP
Sbjct  181  GYRHAADTRLVNVHVQRLRAKVETDPENPEVVLTVRGVGYKAGPP  225


>gi|256380300|ref|YP_003103960.1| winged helix family two component transcriptional regulator [Actinosynnema 
mirum DSM 43827]
 gi|255924603|gb|ACU40114.1| two component transcriptional regulator, winged helix family 
[Actinosynnema mirum DSM 43827]
Length=261

 Score =  377 bits (967),  Expect = 9e-103, Method: Compositional matrix adjust.
 Identities = 184/228 (81%), Positives = 208/228 (92%), Gaps = 0/228 (0%)

Query  1    MDTMRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLP  60
            M TM+ R+LVVDDD +LAEMLTIVLRGEGFDTAV+ DG +AL A+REL+PDLVLLDLMLP
Sbjct  34   MFTMKARVLVVDDDPALAEMLTIVLRGEGFDTAVVADGARALPALRELKPDLVLLDLMLP  93

Query  61   GMNGIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARL  120
            GMNGIDVC+ +R++SGVPIVMLTAK+DTVDVVLGLESGADDY++KPFKPKELVAR+RAR+
Sbjct  94   GMNGIDVCKAIRSESGVPIVMLTAKSDTVDVVLGLESGADDYVVKPFKPKELVARIRARM  153

Query  121  RRNDDEPAEMLSIADVEIDVPAHKVTRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLE  180
            RR + EPAE+L I D+ IDVP H+V R G  I LTPLEFDLLVALARKPRQVFTR+VLLE
Sbjct  154  RRTEAEPAEVLQIGDLTIDVPGHEVLREGRPIQLTPLEFDLLVALARKPRQVFTREVLLE  213

Query  181  QVWGYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP  228
            QVWGYRH ADTRLVNVHVQRLR+KVE+DPE+P VVLTVRGVGYKAGPP
Sbjct  214  QVWGYRHAADTRLVNVHVQRLRSKVERDPEHPEVVLTVRGVGYKAGPP  261


>gi|312140675|ref|YP_004008011.1| two component system response regulator mtra [Rhodococcus equi 
103S]
 gi|325675695|ref|ZP_08155379.1| DNA-binding response regulator [Rhodococcus equi ATCC 33707]
 gi|311890014|emb|CBH49332.1| two component system response regulator MtrA [Rhodococcus equi 
103S]
 gi|325553666|gb|EGD23344.1| DNA-binding response regulator [Rhodococcus equi ATCC 33707]
Length=225

 Score =  376 bits (965),  Expect = 2e-102, Method: Compositional matrix adjust.
 Identities = 200/225 (89%), Positives = 212/225 (95%), Gaps = 0/225 (0%)

Query  4    MRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLPGMN  63
            M+ RILVVDDD +LAEMLTIVLRGEGF+  V+GDG+QALTAVRE RPDLVLLDLMLPGMN
Sbjct  1    MKPRILVVDDDTALAEMLTIVLRGEGFEPYVVGDGSQALTAVRETRPDLVLLDLMLPGMN  60

Query  64   GIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARLRRN  123
            GIDVCRVLRA+SGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARLRR 
Sbjct  61   GIDVCRVLRAESGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARLRRT  120

Query  124  DDEPAEMLSIADVEIDVPAHKVTRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLEQVW  183
            ++EPAE+LSI D+ IDVPAHKVTR+   ISLTPLEFDLLVALARKPRQVFTR+VLLEQVW
Sbjct  121  EEEPAEVLSIGDIMIDVPAHKVTRDNALISLTPLEFDLLVALARKPRQVFTREVLLEQVW  180

Query  184  GYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP  228
            GYRH ADTRLVNVHVQRLRAKVEKDPENP VVLTVRGVGYKAGPP
Sbjct  181  GYRHAADTRLVNVHVQRLRAKVEKDPENPEVVLTVRGVGYKAGPP  225


>gi|319949856|ref|ZP_08023868.1| DNA-binding response regulator MtrA [Dietzia cinnamea P4]
 gi|319436481|gb|EFV91589.1| DNA-binding response regulator MtrA [Dietzia cinnamea P4]
Length=226

 Score =  369 bits (946),  Expect = 2e-100, Method: Compositional matrix adjust.
 Identities = 183/224 (82%), Positives = 200/224 (90%), Gaps = 0/224 (0%)

Query  4    MRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLPGMN  63
            M  +ILVVDDDA+LAEMLTIVLRGEGF+T ++GDG QA+   R ++PDLVLLDLMLPG +
Sbjct  1    MTPKILVVDDDAALAEMLTIVLRGEGFETEIVGDGVQAIETFRAVQPDLVLLDLMLPGKS  60

Query  64   GIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARLRRN  123
            GIDVCR +RA+S VPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVAR+RARLRR 
Sbjct  61   GIDVCREIRAESRVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARIRARLRRG  120

Query  124  DDEPAEMLSIADVEIDVPAHKVTRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLEQVW  183
            +DEP+E L I DV IDVPAH VTR+G  I LTPLEFDLLV LARKPRQVFTR+VLLE VW
Sbjct  121  EDEPSETLHIGDVTIDVPAHTVTRDGTPIPLTPLEFDLLVELARKPRQVFTREVLLEHVW  180

Query  184  GYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGP  227
            GYRH ADTRLVNVHVQRLRAK+EKDPENP VVLTVRGVGYKAGP
Sbjct  181  GYRHSADTRLVNVHVQRLRAKIEKDPENPEVVLTVRGVGYKAGP  224


>gi|331698935|ref|YP_004335174.1| winged helix family two component transcriptional regulator [Pseudonocardia 
dioxanivorans CB1190]
 gi|326953624|gb|AEA27321.1| two component transcriptional regulator, winged helix family 
[Pseudonocardia dioxanivorans CB1190]
Length=225

 Score =  368 bits (945),  Expect = 4e-100, Method: Compositional matrix adjust.
 Identities = 189/225 (84%), Positives = 213/225 (95%), Gaps = 0/225 (0%)

Query  4    MRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLPGMN  63
            M+ R+LVVDDD +LAEMLTIVLRGEGFDTAV+GDGT+AL AVRELRPD+VLLDLMLPGMN
Sbjct  1    MKSRVLVVDDDPALAEMLTIVLRGEGFDTAVVGDGTKALPAVRELRPDVVLLDLMLPGMN  60

Query  64   GIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARLRRN  123
            GIDVCR +R++SGVPIVMLTAK+DTVD+VLGLESGADDY++KPFKPKELVAR+RAR+RR 
Sbjct  61   GIDVCRAIRSESGVPIVMLTAKSDTVDIVLGLESGADDYVVKPFKPKELVARIRARVRRV  120

Query  124  DDEPAEMLSIADVEIDVPAHKVTRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLEQVW  183
            ++EPAE LSI DV+IDVPAH+VTR G  I+LTPLEFDLLVALARKPRQVFTR+VLLEQVW
Sbjct  121  ENEPAEQLSIGDVDIDVPAHQVTRGGVPIALTPLEFDLLVALARKPRQVFTREVLLEQVW  180

Query  184  GYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP  228
            GYRH ADTRLVNVHVQRLR+KVE+DPE+P VVLTVRGVGYKAGPP
Sbjct  181  GYRHAADTRLVNVHVQRLRSKVERDPEHPEVVLTVRGVGYKAGPP  225


>gi|296138804|ref|YP_003646047.1| winged helix family two component transcriptional regulator [Tsukamurella 
paurometabola DSM 20162]
 gi|296026938|gb|ADG77708.1| two component transcriptional regulator, winged helix family 
[Tsukamurella paurometabola DSM 20162]
Length=228

 Score =  365 bits (936),  Expect = 4e-99, Method: Compositional matrix adjust.
 Identities = 190/227 (84%), Positives = 208/227 (92%), Gaps = 0/227 (0%)

Query  1    MDTMRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLP  60
            MD+M+ RILV+DDD +LAEMLTIVLR EGFD+ V+GDGTQAL A RE RPDLVLLDLMLP
Sbjct  1    MDSMKPRILVIDDDPALAEMLTIVLRNEGFDSMVVGDGTQALGAAREFRPDLVLLDLMLP  60

Query  61   GMNGIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARL  120
            GMNGIDV RVLRADS VPIVMLTAK DTVDVVLGLESGADDY++KPFKPKELVARVRARL
Sbjct  61   GMNGIDVARVLRADSNVPIVMLTAKADTVDVVLGLESGADDYVIKPFKPKELVARVRARL  120

Query  121  RRNDDEPAEMLSIADVEIDVPAHKVTRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLE  180
            RR  DEP+E+LSI +V IDVPAHKVTR+GE + LTP EFDLLV +ARKPRQVFTRDVLLE
Sbjct  121  RRTADEPSELLSIGNVIIDVPAHKVTRDGEVVPLTPTEFDLLVTMARKPRQVFTRDVLLE  180

Query  181  QVWGYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGP  227
            QVWGYRHPADTRLVNVH+QRLRAK+EKDPENP +VLT+RGVGYKAGP
Sbjct  181  QVWGYRHPADTRLVNVHIQRLRAKIEKDPENPEIVLTLRGVGYKAGP  227


>gi|302530020|ref|ZP_07282362.1| phosphate regulon transcriptional regulatory protein PhoB [Streptomyces 
sp. AA4]
 gi|302438915|gb|EFL10731.1| phosphate regulon transcriptional regulatory protein PhoB [Streptomyces 
sp. AA4]
Length=227

 Score =  361 bits (926),  Expect = 6e-98, Method: Compositional matrix adjust.
 Identities = 185/225 (83%), Positives = 210/225 (94%), Gaps = 0/225 (0%)

Query  4    MRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLPGMN  63
            M+ R+LVVDDD +LAEMLTIVLRGEGFDTAV+ DG++AL A+REL+PDLVLLDLMLPGMN
Sbjct  3    MKARVLVVDDDPALAEMLTIVLRGEGFDTAVVADGSRALPALRELKPDLVLLDLMLPGMN  62

Query  64   GIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARLRRN  123
            GIDVC+ +RA+SGVPIVMLTAK+DTVD+VLGLESGADDY++KPFKPKELVARVRAR+RR 
Sbjct  63   GIDVCKAIRAESGVPIVMLTAKSDTVDIVLGLESGADDYVVKPFKPKELVARVRARMRRT  122

Query  124  DDEPAEMLSIADVEIDVPAHKVTRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLEQVW  183
            + EPAE L+I D+ IDVP H+VTR+G+ I LTPLEFDLLVALARKPRQVFTR+VLLEQVW
Sbjct  123  EAEPAESLTIGDLAIDVPGHEVTRDGKAIPLTPLEFDLLVALARKPRQVFTREVLLEQVW  182

Query  184  GYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP  228
            GYRH ADTRLVNVHVQRLR+KVEKDPE+P VVLTVRGVGYKAGPP
Sbjct  183  GYRHAADTRLVNVHVQRLRSKVEKDPEHPEVVLTVRGVGYKAGPP  227


>gi|340531476|gb|AEK46681.1| two component transcriptional regulator, winged helix family 
protein [Amycolatopsis mediterranei S699]
Length=225

 Score =  360 bits (925),  Expect = 7e-98, Method: Compositional matrix adjust.
 Identities = 185/225 (83%), Positives = 209/225 (93%), Gaps = 0/225 (0%)

Query  4    MRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLPGMN  63
            M+ R+LVVDDD +LAEMLTIVLRGEGFDTAV+ DG++AL A+REL+PDLVLLDLMLPGMN
Sbjct  1    MKARVLVVDDDPALAEMLTIVLRGEGFDTAVVADGSRALPALRELKPDLVLLDLMLPGMN  60

Query  64   GIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARLRRN  123
            GIDVC+ +RA+SGVPIVMLTAK+DTVD+VLGLESGADDY++KPFKPKELVARVRAR+RR 
Sbjct  61   GIDVCKAIRAESGVPIVMLTAKSDTVDIVLGLESGADDYVVKPFKPKELVARVRARMRRT  120

Query  124  DDEPAEMLSIADVEIDVPAHKVTRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLEQVW  183
            + EPAE L+I D+ IDVP H+VTR G+ I LTPLEFDLLVALARKPRQVFTR+VLLEQVW
Sbjct  121  EAEPAESLTIGDLAIDVPGHEVTREGKAIPLTPLEFDLLVALARKPRQVFTREVLLEQVW  180

Query  184  GYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP  228
            GYRH ADTRLVNVHVQRLR+KVEKDPE+P VVLTVRGVGYKAGPP
Sbjct  181  GYRHAADTRLVNVHVQRLRSKVEKDPEHPEVVLTVRGVGYKAGPP  225


>gi|300789808|ref|YP_003770099.1| two-component system response regulator [Amycolatopsis mediterranei 
U32]
 gi|299799322|gb|ADJ49697.1| two-component system response regulator [Amycolatopsis mediterranei 
U32]
Length=227

 Score =  360 bits (924),  Expect = 9e-98, Method: Compositional matrix adjust.
 Identities = 185/225 (83%), Positives = 209/225 (93%), Gaps = 0/225 (0%)

Query  4    MRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLPGMN  63
            M+ R+LVVDDD +LAEMLTIVLRGEGFDTAV+ DG++AL A+REL+PDLVLLDLMLPGMN
Sbjct  3    MKARVLVVDDDPALAEMLTIVLRGEGFDTAVVADGSRALPALRELKPDLVLLDLMLPGMN  62

Query  64   GIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARLRRN  123
            GIDVC+ +RA+SGVPIVMLTAK+DTVD+VLGLESGADDY++KPFKPKELVARVRAR+RR 
Sbjct  63   GIDVCKAIRAESGVPIVMLTAKSDTVDIVLGLESGADDYVVKPFKPKELVARVRARMRRT  122

Query  124  DDEPAEMLSIADVEIDVPAHKVTRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLEQVW  183
            + EPAE L+I D+ IDVP H+VTR G+ I LTPLEFDLLVALARKPRQVFTR+VLLEQVW
Sbjct  123  EAEPAESLTIGDLAIDVPGHEVTREGKAIPLTPLEFDLLVALARKPRQVFTREVLLEQVW  182

Query  184  GYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP  228
            GYRH ADTRLVNVHVQRLR+KVEKDPE+P VVLTVRGVGYKAGPP
Sbjct  183  GYRHAADTRLVNVHVQRLRSKVEKDPEHPEVVLTVRGVGYKAGPP  227


>gi|257057064|ref|YP_003134896.1| response regulator with CheY-like receiver domain-containing 
protein and winged-helix DNA-binding domain-containing protein 
[Saccharomonospora viridis DSM 43017]
 gi|256586936|gb|ACU98069.1| response regulator with CheY-like receiver domain protein and 
winged-helix DNA-binding domain protein [Saccharomonospora 
viridis DSM 43017]
Length=225

 Score =  359 bits (921),  Expect = 2e-97, Method: Compositional matrix adjust.
 Identities = 186/225 (83%), Positives = 210/225 (94%), Gaps = 0/225 (0%)

Query  4    MRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLPGMN  63
            M+ R+LVVDDD +LAEMLTIVLRGEGFDTAV+ DG++AL A+REL+PDLVLLDLMLPGMN
Sbjct  1    MKARVLVVDDDPALAEMLTIVLRGEGFDTAVVSDGSRALPALRELKPDLVLLDLMLPGMN  60

Query  64   GIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARLRRN  123
            GIDVC+ +RA+SGVPIVMLTAK+DTVD+VLGLESGADDY++KPFKPKELVARVRARLRR 
Sbjct  61   GIDVCKAIRAESGVPIVMLTAKSDTVDIVLGLESGADDYVVKPFKPKELVARVRARLRRT  120

Query  124  DDEPAEMLSIADVEIDVPAHKVTRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLEQVW  183
            + EPAE L+I D+ IDVP H+VTR+G+ I LTPLEFDLLVALARKPRQVFTR+VLLEQVW
Sbjct  121  ESEPAETLTIGDLTIDVPGHEVTRDGKAIPLTPLEFDLLVALARKPRQVFTREVLLEQVW  180

Query  184  GYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP  228
            GYRH ADTRLVNVHVQRLR+KVEKDPE+P VVLTVRGVGYKAGPP
Sbjct  181  GYRHAADTRLVNVHVQRLRSKVEKDPEHPEVVLTVRGVGYKAGPP  225


>gi|325002114|ref|ZP_08123226.1| two-component response regulator [Pseudonocardia sp. P1]
Length=225

 Score =  359 bits (921),  Expect = 2e-97, Method: Compositional matrix adjust.
 Identities = 184/225 (82%), Positives = 210/225 (94%), Gaps = 0/225 (0%)

Query  4    MRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLPGMN  63
            M+ R+LVVDDD +LAEMLTIVLRGEGF+TAV+ DGT+AL AVR+++PD+VLLDLMLPGMN
Sbjct  1    MKSRVLVVDDDPALAEMLTIVLRGEGFETAVVSDGTRALPAVRDMQPDVVLLDLMLPGMN  60

Query  64   GIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARLRRN  123
            GIDVCR +RA+SGVPIVMLTAK+DTVDVVLGLESGADDY++KPFKPKELVAR+RAR+RR 
Sbjct  61   GIDVCRAIRAESGVPIVMLTAKSDTVDVVLGLESGADDYVVKPFKPKELVARIRARVRRI  120

Query  124  DDEPAEMLSIADVEIDVPAHKVTRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLEQVW  183
            + EPAE LSI +++IDVPAH+VTR G  I+LTPLEFDLLVALARKPRQVFTR+VLLEQVW
Sbjct  121  ETEPAEQLSIGEIDIDVPAHQVTRGGRPIALTPLEFDLLVALARKPRQVFTREVLLEQVW  180

Query  184  GYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP  228
            GYRH ADTRLVNVHVQRLR+KVE+DPE P VVLTVRGVGYKAGPP
Sbjct  181  GYRHAADTRLVNVHVQRLRSKVERDPERPEVVLTVRGVGYKAGPP  225


>gi|134102881|ref|YP_001108542.1| two-component response regulator [Saccharopolyspora erythraea 
NRRL 2338]
 gi|133915504|emb|CAM05617.1| two-component response regulator [Saccharopolyspora erythraea 
NRRL 2338]
Length=228

 Score =  358 bits (920),  Expect = 2e-97, Method: Compositional matrix adjust.
 Identities = 185/228 (82%), Positives = 210/228 (93%), Gaps = 0/228 (0%)

Query  1    MDTMRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLP  60
            M  M+ R+LVVDDD +LAEMLTIVLRGEGF+TAV+ DGT+A+ A+REL+PDLVLLDLMLP
Sbjct  1    MWGMKARVLVVDDDPALAEMLTIVLRGEGFETAVVSDGTKAMPALRELKPDLVLLDLMLP  60

Query  61   GMNGIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARL  120
            GMNGIDVC+ +R +S VPIVMLTAK+DTVDVVLGLESGADDY++KPFKPKELVAR+RARL
Sbjct  61   GMNGIDVCKAIRTESVVPIVMLTAKSDTVDVVLGLESGADDYVVKPFKPKELVARLRARL  120

Query  121  RRNDDEPAEMLSIADVEIDVPAHKVTRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLE  180
            RR D EPAE+LSI D+ IDVP H+VTR+G+ I+LTPLEFDLLVALARKPRQVFTR+VLLE
Sbjct  121  RRTDAEPAEVLSIGDLTIDVPGHEVTRDGQPIALTPLEFDLLVALARKPRQVFTREVLLE  180

Query  181  QVWGYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP  228
            QVWGYRH ADTRLVNVHVQRLR+KVE+DPE P VVLTVRGVGYKAGPP
Sbjct  181  QVWGYRHAADTRLVNVHVQRLRSKVERDPERPEVVLTVRGVGYKAGPP  228


>gi|296394611|ref|YP_003659495.1| transcriptional regulator [Segniliparus rotundus DSM 44985]
 gi|296181758|gb|ADG98664.1| two component transcriptional regulator, winged helix family 
[Segniliparus rotundus DSM 44985]
Length=228

 Score =  354 bits (909),  Expect = 5e-96, Method: Compositional matrix adjust.
 Identities = 189/228 (83%), Positives = 209/228 (92%), Gaps = 0/228 (0%)

Query  1    MDTMRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLP  60
            M+ MRQRILVVDDD +LAEMLTIVLRGEGFD  V+ DGT+ L AVRELRPDLVLLD+MLP
Sbjct  1    MNAMRQRILVVDDDVALAEMLTIVLRGEGFDPVVVSDGTKVLPAVRELRPDLVLLDVMLP  60

Query  61   GMNGIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARL  120
            G+NGIDVCR +RA+SGVPIVMLTA+TDT+DVV+GLESGADDY+MKPFKPKELVARVRARL
Sbjct  61   GLNGIDVCRQVRAESGVPIVMLTARTDTIDVVVGLESGADDYVMKPFKPKELVARVRARL  120

Query  121  RRNDDEPAEMLSIADVEIDVPAHKVTRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLE  180
            RRN+    E+L+I DVEIDV AH+V+R  + ISLTPLEFDLLVALARKPRQVFTR+VLLE
Sbjct  121  RRNEVAAPEVLTIDDVEIDVLAHRVSRGDQIISLTPLEFDLLVALARKPRQVFTREVLLE  180

Query  181  QVWGYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP  228
            QVWGYRHPADTRLVNVHVQRLRAKVEKDP+ P VVLTVRGVGYKAGPP
Sbjct  181  QVWGYRHPADTRLVNVHVQRLRAKVEKDPDAPRVVLTVRGVGYKAGPP  228


>gi|317508033|ref|ZP_07965722.1| response regulator receiver domain-containing protein [Segniliparus 
rugosus ATCC BAA-974]
 gi|316253672|gb|EFV13053.1| response regulator receiver domain-containing protein [Segniliparus 
rugosus ATCC BAA-974]
Length=228

 Score =  352 bits (903),  Expect = 2e-95, Method: Compositional matrix adjust.
 Identities = 188/228 (83%), Positives = 209/228 (92%), Gaps = 0/228 (0%)

Query  1    MDTMRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLP  60
            M+ MRQRILVVDDD +LAEMLTIVLRGEGFD  V+ DG++ L AVRELRPDLVLLD+MLP
Sbjct  1    MNPMRQRILVVDDDVALAEMLTIVLRGEGFDPVVVSDGSKVLPAVRELRPDLVLLDVMLP  60

Query  61   GMNGIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARL  120
            G+NGIDVCR +RA+SGVPIVMLTA+TDT+DVV+GLESGADDY+MKPFKPKELVARVRARL
Sbjct  61   GLNGIDVCRQVRAESGVPIVMLTARTDTIDVVVGLESGADDYVMKPFKPKELVARVRARL  120

Query  121  RRNDDEPAEMLSIADVEIDVPAHKVTRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLE  180
            RRN+    E+L+I DVEIDV AH+V+R  + ISLTPLEFDLLVALARKPRQVFTR+VLLE
Sbjct  121  RRNEVAAPEVLTIDDVEIDVLAHRVSRADQIISLTPLEFDLLVALARKPRQVFTREVLLE  180

Query  181  QVWGYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP  228
            QVWGYRHPADTRLVNVHVQRLRAKVEKDP+ P VVLTVRGVGYKAGPP
Sbjct  181  QVWGYRHPADTRLVNVHVQRLRAKVEKDPDAPRVVLTVRGVGYKAGPP  228


>gi|302560333|ref|ZP_07312675.1| DNA-binding response regulator [Streptomyces griseoflavus Tu4000]
 gi|302477951|gb|EFL41044.1| DNA-binding response regulator [Streptomyces griseoflavus Tu4000]
Length=229

 Score =  350 bits (898),  Expect = 9e-95, Method: Compositional matrix adjust.
 Identities = 170/227 (75%), Positives = 200/227 (89%), Gaps = 0/227 (0%)

Query  1    MDTMRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLP  60
            M  M+ R+LVVDDD++LAEML IVLRGEGF+ + + DG +AL A RE +PDLVLLDLMLP
Sbjct  2    MSFMKGRVLVVDDDSALAEMLGIVLRGEGFEPSFVADGDKALAAFREAKPDLVLLDLMLP  61

Query  61   GMNGIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARL  120
            G +GI+VCR++RA+SGVPIVMLTAK+DTVDVV+GLESGADDYI+KPFKPKELVAR+RARL
Sbjct  62   GRDGIEVCRLIRAESGVPIVMLTAKSDTVDVVVGLESGADDYIVKPFKPKELVARIRARL  121

Query  121  RRNDDEPAEMLSIADVEIDVPAHKVTRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLE  180
            RR+++   E L+I D+ IDV  H V R+G+ I+LTPLEFDLLVALARKP QVFTR+VLLE
Sbjct  122  RRSEEPAPEQLAIGDLVIDVAGHSVKRDGQSIALTPLEFDLLVALARKPWQVFTREVLLE  181

Query  181  QVWGYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGP  227
            QVWGYRH ADTRLVNVHVQRLR+KVEKDPE P +V+TVRGVGYKAGP
Sbjct  182  QVWGYRHAADTRLVNVHVQRLRSKVEKDPEKPEIVVTVRGVGYKAGP  228


>gi|291439275|ref|ZP_06578665.1| two-component system response regulator [Streptomyces ghanaensis 
ATCC 14672]
 gi|291342170|gb|EFE69126.1| two-component system response regulator [Streptomyces ghanaensis 
ATCC 14672]
Length=229

 Score =  350 bits (898),  Expect = 9e-95, Method: Compositional matrix adjust.
 Identities = 170/227 (75%), Positives = 200/227 (89%), Gaps = 0/227 (0%)

Query  1    MDTMRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLP  60
            M  M+ R+LVVDDD++LAEML IVLRGEGF+ + + DG +AL A RE +PDLVLLDLMLP
Sbjct  2    MSFMKGRVLVVDDDSALAEMLGIVLRGEGFEPSFVADGDKALAAFRETKPDLVLLDLMLP  61

Query  61   GMNGIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARL  120
            G +GI+VCR++RA+SGVPIVMLTAK+DTVDVV+GLESGADDYI+KPFKPKELVAR+RARL
Sbjct  62   GRDGIEVCRLIRAESGVPIVMLTAKSDTVDVVVGLESGADDYIVKPFKPKELVARIRARL  121

Query  121  RRNDDEPAEMLSIADVEIDVPAHKVTRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLE  180
            RR+++   E L+I D+ IDV  H V R+G+ I+LTPLEFDLLVALARKP QVFTR+VLLE
Sbjct  122  RRSEEPAPEQLAIGDLVIDVAGHSVKRDGQSIALTPLEFDLLVALARKPWQVFTREVLLE  181

Query  181  QVWGYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGP  227
            QVWGYRH ADTRLVNVHVQRLR+KVEKDPE P +V+TVRGVGYKAGP
Sbjct  182  QVWGYRHAADTRLVNVHVQRLRSKVEKDPEKPEIVVTVRGVGYKAGP  228


>gi|10281108|gb|AAG15433.1|AF189161_1 putative response regulator [Streptomyces coelicolor]
Length=228

 Score =  350 bits (897),  Expect = 1e-94, Method: Compositional matrix adjust.
 Identities = 170/227 (75%), Positives = 199/227 (88%), Gaps = 0/227 (0%)

Query  1    MDTMRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLP  60
            M  M+ R+LVVDDD +LAEML IVLRGEGF+ + + DG +AL A RE +PDLVLLDLMLP
Sbjct  1    MSFMKGRVLVVDDDTALAEMLGIVLRGEGFEPSFVADGDKALAAFRETKPDLVLLDLMLP  60

Query  61   GMNGIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARL  120
            G +GI+VCR++RA+SGVPIVMLTAK+DTVDVV+GLESGADDYI+KPFKPKELVAR+RARL
Sbjct  61   GRDGIEVCRLIRAESGVPIVMLTAKSDTVDVVVGLESGADDYIVKPFKPKELVARIRARL  120

Query  121  RRNDDEPAEMLSIADVEIDVPAHKVTRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLE  180
            RR+++   E L+I D+ IDV  H V R+G+ I+LTPLEFDLLVALARKP QVFTR+VLLE
Sbjct  121  RRSEEPAPEQLAIGDLVIDVAGHSVKRDGQSIALTPLEFDLLVALARKPWQVFTREVLLE  180

Query  181  QVWGYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGP  227
            QVWGYRH ADTRLVNVHVQRLR+KVEKDPE P +V+TVRGVGYKAGP
Sbjct  181  QVWGYRHAADTRLVNVHVQRLRSKVEKDPEKPEIVVTVRGVGYKAGP  227


>gi|254392878|ref|ZP_05008047.1| two-component system response regulator [Streptomyces clavuligerus 
ATCC 27064]
 gi|197706534|gb|EDY52346.1| two-component system response regulator [Streptomyces clavuligerus 
ATCC 27064]
Length=229

 Score =  349 bits (896),  Expect = 1e-94, Method: Compositional matrix adjust.
 Identities = 170/227 (75%), Positives = 199/227 (88%), Gaps = 0/227 (0%)

Query  1    MDTMRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLP  60
            M  M+ R+LVVDDD +LAEML IVLRGEGF+ + + DG +AL A RE +PDLVLLDLMLP
Sbjct  2    MSIMKGRVLVVDDDTALAEMLGIVLRGEGFEPSFVADGDKALAAFREAKPDLVLLDLMLP  61

Query  61   GMNGIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARL  120
            G +GI+VCR++RA+SGVPIVMLTAK+DTVDVV+GLESGADDYI+KPFKPKELVAR+RARL
Sbjct  62   GRDGIEVCRLIRAESGVPIVMLTAKSDTVDVVVGLESGADDYIIKPFKPKELVARIRARL  121

Query  121  RRNDDEPAEMLSIADVEIDVPAHKVTRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLE  180
            RR+++   E L+I D+ IDV  H V R+G+ I+LTPLEFDLLVALARKP QVFTR+VLLE
Sbjct  122  RRSEEPAPEQLTIGDLVIDVAGHSVKRDGQSIALTPLEFDLLVALARKPWQVFTREVLLE  181

Query  181  QVWGYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGP  227
            QVWGYRH ADTRLVNVHVQRLR+KVEKDPE P +V+TVRGVGYKAGP
Sbjct  182  QVWGYRHAADTRLVNVHVQRLRSKVEKDPERPEIVVTVRGVGYKAGP  228


>gi|21221456|ref|NP_627235.1| two-component system response regulator [Streptomyces coelicolor 
A3(2)]
 gi|289771258|ref|ZP_06530636.1| two-component system response regulator [Streptomyces lividans 
TK24]
 gi|7799208|emb|CAB90924.1| putative two-component system response regulator [Streptomyces 
coelicolor A3(2)]
 gi|289701457|gb|EFD68886.1| two-component system response regulator [Streptomyces lividans 
TK24]
Length=229

 Score =  349 bits (896),  Expect = 1e-94, Method: Compositional matrix adjust.
 Identities = 170/227 (75%), Positives = 199/227 (88%), Gaps = 0/227 (0%)

Query  1    MDTMRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLP  60
            M  M+ R+LVVDDD +LAEML IVLRGEGF+ + + DG +AL A RE +PDLVLLDLMLP
Sbjct  2    MSFMKGRVLVVDDDTALAEMLGIVLRGEGFEPSFVADGDKALAAFRETKPDLVLLDLMLP  61

Query  61   GMNGIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARL  120
            G +GI+VCR++RA+SGVPIVMLTAK+DTVDVV+GLESGADDYI+KPFKPKELVAR+RARL
Sbjct  62   GRDGIEVCRLIRAESGVPIVMLTAKSDTVDVVVGLESGADDYIVKPFKPKELVARIRARL  121

Query  121  RRNDDEPAEMLSIADVEIDVPAHKVTRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLE  180
            RR+++   E L+I D+ IDV  H V R+G+ I+LTPLEFDLLVALARKP QVFTR+VLLE
Sbjct  122  RRSEEPAPEQLAIGDLVIDVAGHSVKRDGQSIALTPLEFDLLVALARKPWQVFTREVLLE  181

Query  181  QVWGYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGP  227
            QVWGYRH ADTRLVNVHVQRLR+KVEKDPE P +V+TVRGVGYKAGP
Sbjct  182  QVWGYRHAADTRLVNVHVQRLRSKVEKDPEKPEIVVTVRGVGYKAGP  228


>gi|294629682|ref|ZP_06708242.1| DNA-binding response regulator [Streptomyces sp. e14]
 gi|292833015|gb|EFF91364.1| DNA-binding response regulator [Streptomyces sp. e14]
Length=229

 Score =  349 bits (896),  Expect = 2e-94, Method: Compositional matrix adjust.
 Identities = 170/227 (75%), Positives = 199/227 (88%), Gaps = 0/227 (0%)

Query  1    MDTMRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLP  60
            M  M+ R+LVVDDD +LAEML IVLRGEGF+ + + DG +AL A RE +PDLVLLDLMLP
Sbjct  2    MSFMKGRVLVVDDDTALAEMLGIVLRGEGFEPSFVADGDKALAAFREAKPDLVLLDLMLP  61

Query  61   GMNGIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARL  120
            G +GI+VCR++RA+SGVPIVMLTAK+DTVDVV+GLESGADDYI+KPFKPKELVAR+RARL
Sbjct  62   GRDGIEVCRLIRAESGVPIVMLTAKSDTVDVVVGLESGADDYIVKPFKPKELVARIRARL  121

Query  121  RRNDDEPAEMLSIADVEIDVPAHKVTRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLE  180
            RR+++   E L+I D+ IDV  H V R+G+ I+LTPLEFDLLVALARKP QVFTR+VLLE
Sbjct  122  RRSEEPAPEQLAIGDLVIDVAGHSVKRDGQSIALTPLEFDLLVALARKPWQVFTREVLLE  181

Query  181  QVWGYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGP  227
            QVWGYRH ADTRLVNVHVQRLR+KVEKDPE P +V+TVRGVGYKAGP
Sbjct  182  QVWGYRHAADTRLVNVHVQRLRSKVEKDPEKPEIVVTVRGVGYKAGP  228


>gi|302551833|ref|ZP_07304175.1| phosphate regulon transcriptional regulatory protein PhoB [Streptomyces 
viridochromogenes DSM 40736]
 gi|302469451|gb|EFL32544.1| phosphate regulon transcriptional regulatory protein PhoB [Streptomyces 
viridochromogenes DSM 40736]
Length=229

 Score =  349 bits (896),  Expect = 2e-94, Method: Compositional matrix adjust.
 Identities = 170/227 (75%), Positives = 199/227 (88%), Gaps = 0/227 (0%)

Query  1    MDTMRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLP  60
            M  M+ R+LVVDDD +LAEML IVLRGEGF+ + + DG +AL A RE +PDLVLLDLMLP
Sbjct  2    MSFMKGRVLVVDDDTALAEMLGIVLRGEGFEPSFVADGDKALAAFRESKPDLVLLDLMLP  61

Query  61   GMNGIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARL  120
            G +GI+VCR++RA+SGVPIVMLTAK+DTVDVV+GLESGADDYI+KPFKPKELVAR+RARL
Sbjct  62   GRDGIEVCRLIRAESGVPIVMLTAKSDTVDVVVGLESGADDYIVKPFKPKELVARIRARL  121

Query  121  RRNDDEPAEMLSIADVEIDVPAHKVTRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLE  180
            RR+++   E L+I D+ IDV  H V R+G+ I+LTPLEFDLLVALARKP QVFTR+VLLE
Sbjct  122  RRSEEPAPEQLAIGDLVIDVAGHSVKRDGQSIALTPLEFDLLVALARKPWQVFTREVLLE  181

Query  181  QVWGYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGP  227
            QVWGYRH ADTRLVNVHVQRLR+KVEKDPE P +V+TVRGVGYKAGP
Sbjct  182  QVWGYRHAADTRLVNVHVQRLRSKVEKDPEKPEIVVTVRGVGYKAGP  228


>gi|291445133|ref|ZP_06584523.1| two-component system response regulator [Streptomyces roseosporus 
NRRL 15998]
 gi|291348080|gb|EFE74984.1| two-component system response regulator [Streptomyces roseosporus 
NRRL 15998]
Length=228

 Score =  349 bits (895),  Expect = 2e-94, Method: Compositional matrix adjust.
 Identities = 170/227 (75%), Positives = 198/227 (88%), Gaps = 0/227 (0%)

Query  1    MDTMRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLP  60
            M  M+ R+LVVDDD +LAEML IVLRGEGF+ + + DG +AL A RE +PDLVLLDLMLP
Sbjct  1    MSIMKGRVLVVDDDTALAEMLGIVLRGEGFEPSFVADGDKALAAFREAKPDLVLLDLMLP  60

Query  61   GMNGIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARL  120
            G +GI+VCR++RA+SGVPIVMLTAK+DTVDVV+GLESGADDYI+KPFKPKELVAR+RARL
Sbjct  61   GRDGIEVCRLIRAESGVPIVMLTAKSDTVDVVVGLESGADDYIVKPFKPKELVARIRARL  120

Query  121  RRNDDEPAEMLSIADVEIDVPAHKVTRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLE  180
            RR+++   E L+I D+ IDV  H V R G+ I+LTPLEFDLLVALARKP QVFTR+VLLE
Sbjct  121  RRSEEPAPEQLTIGDLVIDVAGHSVKREGQSIALTPLEFDLLVALARKPWQVFTREVLLE  180

Query  181  QVWGYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGP  227
            QVWGYRH ADTRLVNVHVQRLR+KVEKDPE P +V+TVRGVGYKAGP
Sbjct  181  QVWGYRHAADTRLVNVHVQRLRSKVEKDPERPEIVVTVRGVGYKAGP  227


>gi|302534786|ref|ZP_07287128.1| phosphate regulon transcriptional regulatory protein PhoB [Streptomyces 
sp. C]
 gi|302443681|gb|EFL15497.1| phosphate regulon transcriptional regulatory protein PhoB [Streptomyces 
sp. C]
Length=229

 Score =  349 bits (895),  Expect = 2e-94, Method: Compositional matrix adjust.
 Identities = 171/227 (76%), Positives = 198/227 (88%), Gaps = 0/227 (0%)

Query  1    MDTMRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLP  60
            M TM+ R+LVVDDD +LAEML IVLRGEGF+ + + DG +AL A RE +PDLVLLDLMLP
Sbjct  2    MSTMKGRVLVVDDDTALAEMLGIVLRGEGFEPSFVADGDKALAAFREAKPDLVLLDLMLP  61

Query  61   GMNGIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARL  120
            G +GI+VCR++RA+SGVPIVMLTAK+DTVDVV+GLESGADDYI+KPFKPKELVAR+RARL
Sbjct  62   GRDGIEVCRLIRAESGVPIVMLTAKSDTVDVVVGLESGADDYIVKPFKPKELVARIRARL  121

Query  121  RRNDDEPAEMLSIADVEIDVPAHKVTRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLE  180
            RR+++   E L I D+ IDV  H V R+G  I+LTPLEFDLLVALARKP QVFTR+VLLE
Sbjct  122  RRSEEPAPEQLVIGDLVIDVAGHSVKRDGASIALTPLEFDLLVALARKPWQVFTREVLLE  181

Query  181  QVWGYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGP  227
            QVWGYRH ADTRLVNVHVQRLR+KVEKDPE P +V+TVRGVGYKAGP
Sbjct  182  QVWGYRHAADTRLVNVHVQRLRSKVEKDPERPEIVVTVRGVGYKAGP  228


>gi|297194039|ref|ZP_06911437.1| two-component system response regulator [Streptomyces pristinaespiralis 
ATCC 25486]
 gi|297152078|gb|EFH31517.1| two-component system response regulator [Streptomyces pristinaespiralis 
ATCC 25486]
Length=229

 Score =  349 bits (895),  Expect = 2e-94, Method: Compositional matrix adjust.
 Identities = 170/227 (75%), Positives = 199/227 (88%), Gaps = 0/227 (0%)

Query  1    MDTMRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLP  60
            M  M+ R+LVVDDD +LAEML IVLRGEGF+ + + DG +AL A RE +PDLVLLDLMLP
Sbjct  2    MSFMKGRVLVVDDDTALAEMLGIVLRGEGFEPSFVADGDKALAAFREAKPDLVLLDLMLP  61

Query  61   GMNGIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARL  120
            G +GI+VCR++RA+SGVPIVMLTAK+DTVDVV+GLESGADDYI+KPFKPKELVAR+RARL
Sbjct  62   GRDGIEVCRLIRAESGVPIVMLTAKSDTVDVVVGLESGADDYIVKPFKPKELVARIRARL  121

Query  121  RRNDDEPAEMLSIADVEIDVPAHKVTRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLE  180
            RR+++   E L+I D+ IDV  H V R+G+ I+LTPLEFDLLVALARKP QVFTR+VLLE
Sbjct  122  RRSEEPAPEQLTIGDLVIDVAGHSVKRDGQSIALTPLEFDLLVALARKPWQVFTREVLLE  181

Query  181  QVWGYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGP  227
            QVWGYRH ADTRLVNVHVQRLR+KVEKDPE P +V+TVRGVGYKAGP
Sbjct  182  QVWGYRHAADTRLVNVHVQRLRSKVEKDPERPEIVVTVRGVGYKAGP  228


>gi|182438316|ref|YP_001826035.1| putative two-component system response regulator [Streptomyces 
griseus subsp. griseus NBRC 13350]
 gi|178466832|dbj|BAG21352.1| putative two-component system response regulator [Streptomyces 
griseus subsp. griseus NBRC 13350]
Length=229

 Score =  349 bits (895),  Expect = 2e-94, Method: Compositional matrix adjust.
 Identities = 170/227 (75%), Positives = 198/227 (88%), Gaps = 0/227 (0%)

Query  1    MDTMRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLP  60
            M  M+ R+LVVDDD +LAEML IVLRGEGF+ + + DG +AL A RE +PDLVLLDLMLP
Sbjct  2    MSIMKGRVLVVDDDTALAEMLGIVLRGEGFEPSFVADGDKALAAFREAKPDLVLLDLMLP  61

Query  61   GMNGIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARL  120
            G +GI+VCR++RA+SGVPIVMLTAK+DTVDVV+GLESGADDYI+KPFKPKELVAR+RARL
Sbjct  62   GRDGIEVCRLIRAESGVPIVMLTAKSDTVDVVVGLESGADDYIVKPFKPKELVARIRARL  121

Query  121  RRNDDEPAEMLSIADVEIDVPAHKVTRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLE  180
            RR+++   E L+I D+ IDV  H V R G+ I+LTPLEFDLLVALARKP QVFTR+VLLE
Sbjct  122  RRSEEPAPEQLTIGDLVIDVAGHSVKREGQSIALTPLEFDLLVALARKPWQVFTREVLLE  181

Query  181  QVWGYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGP  227
            QVWGYRH ADTRLVNVHVQRLR+KVEKDPE P +V+TVRGVGYKAGP
Sbjct  182  QVWGYRHAADTRLVNVHVQRLRSKVEKDPERPEIVVTVRGVGYKAGP  228


>gi|291009674|ref|ZP_06567647.1| two-component response regulator [Saccharopolyspora erythraea 
NRRL 2338]
Length=223

 Score =  349 bits (895),  Expect = 2e-94, Method: Compositional matrix adjust.
 Identities = 182/225 (81%), Positives = 207/225 (92%), Gaps = 2/225 (0%)

Query  4    MRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLPGMN  63
            M+ R+LVVDDD +LAEMLTIVLRGEGF+TAV+ DGT+A+ A+REL+PDLVLLDLMLPGMN
Sbjct  1    MKARVLVVDDDPALAEMLTIVLRGEGFETAVVSDGTKAMPALRELKPDLVLLDLMLPGMN  60

Query  64   GIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARLRRN  123
            GIDVC+ +R +S VPIVMLTAK+DTVDVVLGLESGADDY++KPFKPKELVAR+RARLRR 
Sbjct  61   GIDVCKAIRTESVVPIVMLTAKSDTVDVVLGLESGADDYVVKPFKPKELVARLRARLRRT  120

Query  124  DDEPAEMLSIADVEIDVPAHKVTRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLEQVW  183
            D EPAE+LSI D+ IDVP H+VTR+G+ I+LTPLEFDLLVALARKPRQVFTR+VLLEQVW
Sbjct  121  DAEPAEVLSIGDLTIDVPGHEVTRDGQPIALTPLEFDLLVALARKPRQVFTREVLLEQVW  180

Query  184  GYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP  228
            GYRH ADTRLVN  VQRLR+KVE+DPE P VVLTVRGVGYKAGPP
Sbjct  181  GYRHAADTRLVN--VQRLRSKVERDPERPEVVLTVRGVGYKAGPP  223


>gi|294812933|ref|ZP_06771576.1| Two-component system response regulator [Streptomyces clavuligerus 
ATCC 27064]
 gi|294325532|gb|EFG07175.1| Two-component system response regulator [Streptomyces clavuligerus 
ATCC 27064]
Length=260

 Score =  348 bits (894),  Expect = 3e-94, Method: Compositional matrix adjust.
 Identities = 170/227 (75%), Positives = 199/227 (88%), Gaps = 0/227 (0%)

Query  1    MDTMRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLP  60
            M  M+ R+LVVDDD +LAEML IVLRGEGF+ + + DG +AL A RE +PDLVLLDLMLP
Sbjct  33   MSIMKGRVLVVDDDTALAEMLGIVLRGEGFEPSFVADGDKALAAFREAKPDLVLLDLMLP  92

Query  61   GMNGIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARL  120
            G +GI+VCR++RA+SGVPIVMLTAK+DTVDVV+GLESGADDYI+KPFKPKELVAR+RARL
Sbjct  93   GRDGIEVCRLIRAESGVPIVMLTAKSDTVDVVVGLESGADDYIIKPFKPKELVARIRARL  152

Query  121  RRNDDEPAEMLSIADVEIDVPAHKVTRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLE  180
            RR+++   E L+I D+ IDV  H V R+G+ I+LTPLEFDLLVALARKP QVFTR+VLLE
Sbjct  153  RRSEEPAPEQLTIGDLVIDVAGHSVKRDGQSIALTPLEFDLLVALARKPWQVFTREVLLE  212

Query  181  QVWGYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGP  227
            QVWGYRH ADTRLVNVHVQRLR+KVEKDPE P +V+TVRGVGYKAGP
Sbjct  213  QVWGYRHAADTRLVNVHVQRLRSKVEKDPERPEIVVTVRGVGYKAGP  259



Lambda     K      H
   0.321    0.139    0.397 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Effective search space used: 294240045594


  Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
    Posted date:  Sep 5, 2011  4:36 AM
  Number of letters in database: 5,219,829,388
  Number of sequences in database:  15,229,318



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40