BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv3248c Length=495 Score E Sequences producing significant alignments: (Bits) Value gi|15610384|ref|NP_217765.1| S-adenosyl-L-homocysteine hydrolase... 1021 0.0 gi|31794428|ref|NP_856921.1| S-adenosyl-L-homocysteine hydrolase... 1021 0.0 gi|203282393|pdb|3CE6|A Chain A, Crystal Structure Of Mycobacter... 1019 0.0 gi|289755371|ref|ZP_06514749.1| S-adenosyl-L-homocysteine hydrol... 1018 0.0 gi|240172609|ref|ZP_04751268.1| S-adenosyl-L-homocysteine hydrol... 977 0.0 gi|183981317|ref|YP_001849608.1| adenosylhomocysteinase SahH [My... 973 0.0 gi|118618063|ref|YP_906395.1| S-adenosyl-L-homocysteine hydrolas... 971 0.0 gi|15827332|ref|NP_301595.1| S-adenosyl-L-homocysteine hydrolase... 938 0.0 gi|296168957|ref|ZP_06850626.1| adenosylhomocysteinase [Mycobact... 905 0.0 gi|169630675|ref|YP_001704324.1| S-adenosyl-L-homocysteine hydro... 899 0.0 gi|145225295|ref|YP_001135973.1| S-adenosyl-L-homocysteine hydro... 897 0.0 gi|54026586|ref|YP_120828.1| S-adenosyl-L-homocysteine hydrolase... 894 0.0 gi|120402746|ref|YP_952575.1| S-adenosyl-L-homocysteine hydrolas... 890 0.0 gi|126433974|ref|YP_001069665.1| S-adenosyl-L-homocysteine hydro... 889 0.0 gi|254822995|ref|ZP_05227996.1| S-adenosyl-L-homocysteine hydrol... 888 0.0 gi|342861451|ref|ZP_08718098.1| S-adenosyl-L-homocysteine hydrol... 888 0.0 gi|108798307|ref|YP_638504.1| S-adenosyl-L-homocysteine hydrolas... 887 0.0 gi|302595893|sp|A4ZHR8.1|SAHH_MYCS2 RecName: Full=Adenosylhomocy... 885 0.0 gi|343927674|ref|ZP_08767142.1| adenosylhomocysteinase [Gordonia... 883 0.0 gi|262203513|ref|YP_003274721.1| adenosylhomocysteinase [Gordoni... 878 0.0 gi|41409460|ref|NP_962296.1| S-adenosyl-L-homocysteine hydrolase... 877 0.0 gi|118462675|ref|YP_883353.1| S-adenosyl-L-homocysteine hydrolas... 877 0.0 gi|296138919|ref|YP_003646162.1| adenosylhomocysteinase [Tsukamu... 872 0.0 gi|333991628|ref|YP_004524242.1| S-adenosyl-L-homocysteine hydro... 864 0.0 gi|226365792|ref|YP_002783575.1| S-adenosyl-L-homocysteine hydro... 849 0.0 gi|111023285|ref|YP_706257.1| S-adenosyl-L-homocysteine hydrolas... 849 0.0 gi|229489409|ref|ZP_04383272.1| adenosylhomocysteinase [Rhodococ... 848 0.0 gi|312140678|ref|YP_004008014.1| adenosylhomocysteinase sahh [Rh... 844 0.0 gi|226305653|ref|YP_002765613.1| adenosylhomocysteinase [Rhodoco... 843 0.0 gi|326383261|ref|ZP_08204949.1| S-adenosyl-L-homocysteine hydrol... 835 0.0 gi|333921451|ref|YP_004495032.1| adenosylhomocysteinase [Amycoli... 806 0.0 gi|296394615|ref|YP_003659499.1| adenosylhomocysteinase [Segnili... 801 0.0 gi|256380309|ref|YP_003103969.1| S-adenosyl-L-homocysteine hydro... 778 0.0 gi|256377202|ref|YP_003100862.1| S-adenosyl-L-homocysteine hydro... 777 0.0 gi|317508026|ref|ZP_07965716.1| adenosylhomocysteinase [Segnilip... 776 0.0 gi|302530033|ref|ZP_07282375.1| adenosylhomocysteinase [Streptom... 773 0.0 gi|134102884|ref|YP_001108545.1| S-adenosyl-L-homocysteine hydro... 760 0.0 gi|319949854|ref|ZP_08023866.1| S-adenosyl-L-homocysteine hydrol... 760 0.0 gi|300789821|ref|YP_003770112.1| adenosylhomocysteinase [Amycola... 753 0.0 gi|258654379|ref|YP_003203535.1| S-adenosyl-L-homocysteine hydro... 740 0.0 gi|213964853|ref|ZP_03393052.1| adenosylhomocysteinase [Coryneba... 730 0.0 gi|334696306|gb|AEG81103.1| adenosylhomocysteinase [Corynebacter... 730 0.0 gi|19551979|ref|NP_599981.1| S-adenosyl-L-homocysteine hydrolase... 729 0.0 gi|29336780|sp|Q8NSC4.1|SAHH_CORGL RecName: Full=Adenosylhomocys... 728 0.0 gi|337290185|ref|YP_004629206.1| adenosylhomocysteinase [Coryneb... 727 0.0 gi|300857933|ref|YP_003782916.1| adenosylhomocysteinase [Coryneb... 724 0.0 gi|330465911|ref|YP_004403654.1| S-adenosyl-L-homocysteine hydro... 723 0.0 gi|25027323|ref|NP_737377.1| S-adenosyl-L-homocysteine hydrolase... 721 0.0 gi|38233299|ref|NP_939066.1| S-adenosyl-L-homocysteine hydrolase... 719 0.0 gi|68536725|ref|YP_251430.1| S-adenosyl-L-homocysteine hydrolase... 719 0.0 >gi|15610384|ref|NP_217765.1| S-adenosyl-L-homocysteine hydrolase [Mycobacterium tuberculosis H37Rv] gi|15842837|ref|NP_337874.1| S-adenosyl-L-homocysteine hydrolase [Mycobacterium tuberculosis CDC1551] gi|121639137|ref|YP_979361.1| S-adenosyl-L-homocysteine hydrolase [Mycobacterium bovis BCG str. Pasteur 1173P2] 94 more sequence titles Length=495 Score = 1021 bits (2640), Expect = 0.0, Method: Compositional matrix adjust. Identities = 495/495 (100%), Positives = 495/495 (100%), Gaps = 0/495 (0%) Query 1 MTGNLVTKNSLTPDVRNGIDFKIADLSLADFGRKELRIAEHEMPGLMSLRREYAEVQPLK 60 MTGNLVTKNSLTPDVRNGIDFKIADLSLADFGRKELRIAEHEMPGLMSLRREYAEVQPLK Sbjct 1 MTGNLVTKNSLTPDVRNGIDFKIADLSLADFGRKELRIAEHEMPGLMSLRREYAEVQPLK 60 Query 61 GARISGSLHMTVQTAVLIETLTALGAEVRWASCNIFSTQDHAAAAVVVGPHGTPDEPKGV 120 GARISGSLHMTVQTAVLIETLTALGAEVRWASCNIFSTQDHAAAAVVVGPHGTPDEPKGV Sbjct 61 GARISGSLHMTVQTAVLIETLTALGAEVRWASCNIFSTQDHAAAAVVVGPHGTPDEPKGV 120 Query 121 PVFAWKGETLEEYWWAAEQMLTWPDPDKPANMILDDGGDATMLVLRGMQYEKAGVVPPAE 180 PVFAWKGETLEEYWWAAEQMLTWPDPDKPANMILDDGGDATMLVLRGMQYEKAGVVPPAE Sbjct 121 PVFAWKGETLEEYWWAAEQMLTWPDPDKPANMILDDGGDATMLVLRGMQYEKAGVVPPAE 180 Query 181 EDDPAEWKVFLNLLRTRFETDKDKWTKIAESVKGVTEETTTGVLRLYQFAAAGDLAFPAI 240 EDDPAEWKVFLNLLRTRFETDKDKWTKIAESVKGVTEETTTGVLRLYQFAAAGDLAFPAI Sbjct 181 EDDPAEWKVFLNLLRTRFETDKDKWTKIAESVKGVTEETTTGVLRLYQFAAAGDLAFPAI 240 Query 241 NVNDSVTKSKFDNKYGTRHSLIDGINRGTDALIGGKKVLICGYGDVGKGCAEAMKGQGAR 300 NVNDSVTKSKFDNKYGTRHSLIDGINRGTDALIGGKKVLICGYGDVGKGCAEAMKGQGAR Sbjct 241 NVNDSVTKSKFDNKYGTRHSLIDGINRGTDALIGGKKVLICGYGDVGKGCAEAMKGQGAR 300 Query 301 VSVTEIDPINALQAMMEGFDVVTVEEAIGDADIVVTATGNKDIIMLEHIKAMKDHAILGN 360 VSVTEIDPINALQAMMEGFDVVTVEEAIGDADIVVTATGNKDIIMLEHIKAMKDHAILGN Sbjct 301 VSVTEIDPINALQAMMEGFDVVTVEEAIGDADIVVTATGNKDIIMLEHIKAMKDHAILGN 360 Query 361 IGHFDNEIDMAGLERSGATRVNVKPQVDLWTFGDTGRSIIVLSEGRLLNLGNATGHPSFV 420 IGHFDNEIDMAGLERSGATRVNVKPQVDLWTFGDTGRSIIVLSEGRLLNLGNATGHPSFV Sbjct 361 IGHFDNEIDMAGLERSGATRVNVKPQVDLWTFGDTGRSIIVLSEGRLLNLGNATGHPSFV 420 Query 421 MSNSFANQTIAQIELWTKNDEYDNEVYRLPKHLDEKVARIHVEALGGHLTKLTKEQAEYL 480 MSNSFANQTIAQIELWTKNDEYDNEVYRLPKHLDEKVARIHVEALGGHLTKLTKEQAEYL Sbjct 421 MSNSFANQTIAQIELWTKNDEYDNEVYRLPKHLDEKVARIHVEALGGHLTKLTKEQAEYL 480 Query 481 GVDVEGPYKPDHYRY 495 GVDVEGPYKPDHYRY Sbjct 481 GVDVEGPYKPDHYRY 495 >gi|31794428|ref|NP_856921.1| S-adenosyl-L-homocysteine hydrolase [Mycobacterium bovis AF2122/97] gi|39932281|sp|Q7TWW7.3|SAHH_MYCBO RecName: Full=Adenosylhomocysteinase; AltName: Full=S-adenosyl-L-homocysteine hydrolase; Short=AdoHcyase gi|31620024|emb|CAD95368.1| PROBABLE ADENOSYLHOMOCYSTEINASE SAHH (S-ADENOSYL-L-HOMOCYSTEINE HYDROLASE) (ADOHCYASE) [Mycobacterium bovis AF2122/97] Length=495 Score = 1021 bits (2639), Expect = 0.0, Method: Compositional matrix adjust. Identities = 494/495 (99%), Positives = 495/495 (100%), Gaps = 0/495 (0%) Query 1 MTGNLVTKNSLTPDVRNGIDFKIADLSLADFGRKELRIAEHEMPGLMSLRREYAEVQPLK 60 MTGNLVTKNSLTPDVRNGIDFKIADLSLADFGRKELRIAEHEMPGLMSLRREYAEVQPLK Sbjct 1 MTGNLVTKNSLTPDVRNGIDFKIADLSLADFGRKELRIAEHEMPGLMSLRREYAEVQPLK 60 Query 61 GARISGSLHMTVQTAVLIETLTALGAEVRWASCNIFSTQDHAAAAVVVGPHGTPDEPKGV 120 GARISGSLHMTVQTAVLIETLTALGAEVRWASCNIFSTQDHAAAAVVVGPHGTPDEPKGV Sbjct 61 GARISGSLHMTVQTAVLIETLTALGAEVRWASCNIFSTQDHAAAAVVVGPHGTPDEPKGV 120 Query 121 PVFAWKGETLEEYWWAAEQMLTWPDPDKPANMILDDGGDATMLVLRGMQYEKAGVVPPAE 180 PVFAWKGETLEEYWWAAEQMLTWPDPDKPANMILDDGGDATMLVLRGMQYEKAGVVPPAE Sbjct 121 PVFAWKGETLEEYWWAAEQMLTWPDPDKPANMILDDGGDATMLVLRGMQYEKAGVVPPAE 180 Query 181 EDDPAEWKVFLNLLRTRFETDKDKWTKIAESVKGVTEETTTGVLRLYQFAAAGDLAFPAI 240 EDDPAEWK+FLNLLRTRFETDKDKWTKIAESVKGVTEETTTGVLRLYQFAAAGDLAFPAI Sbjct 181 EDDPAEWKIFLNLLRTRFETDKDKWTKIAESVKGVTEETTTGVLRLYQFAAAGDLAFPAI 240 Query 241 NVNDSVTKSKFDNKYGTRHSLIDGINRGTDALIGGKKVLICGYGDVGKGCAEAMKGQGAR 300 NVNDSVTKSKFDNKYGTRHSLIDGINRGTDALIGGKKVLICGYGDVGKGCAEAMKGQGAR Sbjct 241 NVNDSVTKSKFDNKYGTRHSLIDGINRGTDALIGGKKVLICGYGDVGKGCAEAMKGQGAR 300 Query 301 VSVTEIDPINALQAMMEGFDVVTVEEAIGDADIVVTATGNKDIIMLEHIKAMKDHAILGN 360 VSVTEIDPINALQAMMEGFDVVTVEEAIGDADIVVTATGNKDIIMLEHIKAMKDHAILGN Sbjct 301 VSVTEIDPINALQAMMEGFDVVTVEEAIGDADIVVTATGNKDIIMLEHIKAMKDHAILGN 360 Query 361 IGHFDNEIDMAGLERSGATRVNVKPQVDLWTFGDTGRSIIVLSEGRLLNLGNATGHPSFV 420 IGHFDNEIDMAGLERSGATRVNVKPQVDLWTFGDTGRSIIVLSEGRLLNLGNATGHPSFV Sbjct 361 IGHFDNEIDMAGLERSGATRVNVKPQVDLWTFGDTGRSIIVLSEGRLLNLGNATGHPSFV 420 Query 421 MSNSFANQTIAQIELWTKNDEYDNEVYRLPKHLDEKVARIHVEALGGHLTKLTKEQAEYL 480 MSNSFANQTIAQIELWTKNDEYDNEVYRLPKHLDEKVARIHVEALGGHLTKLTKEQAEYL Sbjct 421 MSNSFANQTIAQIELWTKNDEYDNEVYRLPKHLDEKVARIHVEALGGHLTKLTKEQAEYL 480 Query 481 GVDVEGPYKPDHYRY 495 GVDVEGPYKPDHYRY Sbjct 481 GVDVEGPYKPDHYRY 495 >gi|203282393|pdb|3CE6|A Chain A, Crystal Structure Of Mycobacterium Tuberculosis S-Adenosyl- L-Homocysteine Hydrolase In Ternary Complex With Nad And Adenosine gi|203282394|pdb|3CE6|B Chain B, Crystal Structure Of Mycobacterium Tuberculosis S-Adenosyl- L-Homocysteine Hydrolase In Ternary Complex With Nad And Adenosine gi|203282395|pdb|3CE6|C Chain C, Crystal Structure Of Mycobacterium Tuberculosis S-Adenosyl- L-Homocysteine Hydrolase In Ternary Complex With Nad And Adenosine gi|203282396|pdb|3CE6|D Chain D, Crystal Structure Of Mycobacterium Tuberculosis S-Adenosyl- L-Homocysteine Hydrolase In Ternary Complex With Nad And Adenosine Length=494 Score = 1019 bits (2634), Expect = 0.0, Method: Compositional matrix adjust. Identities = 494/494 (100%), Positives = 494/494 (100%), Gaps = 0/494 (0%) Query 2 TGNLVTKNSLTPDVRNGIDFKIADLSLADFGRKELRIAEHEMPGLMSLRREYAEVQPLKG 61 TGNLVTKNSLTPDVRNGIDFKIADLSLADFGRKELRIAEHEMPGLMSLRREYAEVQPLKG Sbjct 1 TGNLVTKNSLTPDVRNGIDFKIADLSLADFGRKELRIAEHEMPGLMSLRREYAEVQPLKG 60 Query 62 ARISGSLHMTVQTAVLIETLTALGAEVRWASCNIFSTQDHAAAAVVVGPHGTPDEPKGVP 121 ARISGSLHMTVQTAVLIETLTALGAEVRWASCNIFSTQDHAAAAVVVGPHGTPDEPKGVP Sbjct 61 ARISGSLHMTVQTAVLIETLTALGAEVRWASCNIFSTQDHAAAAVVVGPHGTPDEPKGVP 120 Query 122 VFAWKGETLEEYWWAAEQMLTWPDPDKPANMILDDGGDATMLVLRGMQYEKAGVVPPAEE 181 VFAWKGETLEEYWWAAEQMLTWPDPDKPANMILDDGGDATMLVLRGMQYEKAGVVPPAEE Sbjct 121 VFAWKGETLEEYWWAAEQMLTWPDPDKPANMILDDGGDATMLVLRGMQYEKAGVVPPAEE 180 Query 182 DDPAEWKVFLNLLRTRFETDKDKWTKIAESVKGVTEETTTGVLRLYQFAAAGDLAFPAIN 241 DDPAEWKVFLNLLRTRFETDKDKWTKIAESVKGVTEETTTGVLRLYQFAAAGDLAFPAIN Sbjct 181 DDPAEWKVFLNLLRTRFETDKDKWTKIAESVKGVTEETTTGVLRLYQFAAAGDLAFPAIN 240 Query 242 VNDSVTKSKFDNKYGTRHSLIDGINRGTDALIGGKKVLICGYGDVGKGCAEAMKGQGARV 301 VNDSVTKSKFDNKYGTRHSLIDGINRGTDALIGGKKVLICGYGDVGKGCAEAMKGQGARV Sbjct 241 VNDSVTKSKFDNKYGTRHSLIDGINRGTDALIGGKKVLICGYGDVGKGCAEAMKGQGARV 300 Query 302 SVTEIDPINALQAMMEGFDVVTVEEAIGDADIVVTATGNKDIIMLEHIKAMKDHAILGNI 361 SVTEIDPINALQAMMEGFDVVTVEEAIGDADIVVTATGNKDIIMLEHIKAMKDHAILGNI Sbjct 301 SVTEIDPINALQAMMEGFDVVTVEEAIGDADIVVTATGNKDIIMLEHIKAMKDHAILGNI 360 Query 362 GHFDNEIDMAGLERSGATRVNVKPQVDLWTFGDTGRSIIVLSEGRLLNLGNATGHPSFVM 421 GHFDNEIDMAGLERSGATRVNVKPQVDLWTFGDTGRSIIVLSEGRLLNLGNATGHPSFVM Sbjct 361 GHFDNEIDMAGLERSGATRVNVKPQVDLWTFGDTGRSIIVLSEGRLLNLGNATGHPSFVM 420 Query 422 SNSFANQTIAQIELWTKNDEYDNEVYRLPKHLDEKVARIHVEALGGHLTKLTKEQAEYLG 481 SNSFANQTIAQIELWTKNDEYDNEVYRLPKHLDEKVARIHVEALGGHLTKLTKEQAEYLG Sbjct 421 SNSFANQTIAQIELWTKNDEYDNEVYRLPKHLDEKVARIHVEALGGHLTKLTKEQAEYLG 480 Query 482 VDVEGPYKPDHYRY 495 VDVEGPYKPDHYRY Sbjct 481 VDVEGPYKPDHYRY 494 >gi|289755371|ref|ZP_06514749.1| S-adenosyl-L-homocysteine hydrolase [Mycobacterium tuberculosis EAS054] gi|289695958|gb|EFD63387.1| S-adenosyl-L-homocysteine hydrolase [Mycobacterium tuberculosis EAS054] Length=495 Score = 1018 bits (2632), Expect = 0.0, Method: Compositional matrix adjust. Identities = 494/495 (99%), Positives = 494/495 (99%), Gaps = 0/495 (0%) Query 1 MTGNLVTKNSLTPDVRNGIDFKIADLSLADFGRKELRIAEHEMPGLMSLRREYAEVQPLK 60 MTGNLVTKNSLTPDVRNGIDFKIADLSLADFGRKELRIAEHEMPGLMSLRREYAEVQPLK Sbjct 1 MTGNLVTKNSLTPDVRNGIDFKIADLSLADFGRKELRIAEHEMPGLMSLRREYAEVQPLK 60 Query 61 GARISGSLHMTVQTAVLIETLTALGAEVRWASCNIFSTQDHAAAAVVVGPHGTPDEPKGV 120 GARISGSLHMTVQTAVLIETLTALGAEVRWASCNIFSTQDHAAAAVVVGPHGTPDEPKGV Sbjct 61 GARISGSLHMTVQTAVLIETLTALGAEVRWASCNIFSTQDHAAAAVVVGPHGTPDEPKGV 120 Query 121 PVFAWKGETLEEYWWAAEQMLTWPDPDKPANMILDDGGDATMLVLRGMQYEKAGVVPPAE 180 PVFAWKGETLEEYWWAAEQMLTWPDPDK ANMILDDGGDATMLVLRGMQYEKAGVVPPAE Sbjct 121 PVFAWKGETLEEYWWAAEQMLTWPDPDKSANMILDDGGDATMLVLRGMQYEKAGVVPPAE 180 Query 181 EDDPAEWKVFLNLLRTRFETDKDKWTKIAESVKGVTEETTTGVLRLYQFAAAGDLAFPAI 240 EDDPAEWKVFLNLLRTRFETDKDKWTKIAESVKGVTEETTTGVLRLYQFAAAGDLAFPAI Sbjct 181 EDDPAEWKVFLNLLRTRFETDKDKWTKIAESVKGVTEETTTGVLRLYQFAAAGDLAFPAI 240 Query 241 NVNDSVTKSKFDNKYGTRHSLIDGINRGTDALIGGKKVLICGYGDVGKGCAEAMKGQGAR 300 NVNDSVTKSKFDNKYGTRHSLIDGINRGTDALIGGKKVLICGYGDVGKGCAEAMKGQGAR Sbjct 241 NVNDSVTKSKFDNKYGTRHSLIDGINRGTDALIGGKKVLICGYGDVGKGCAEAMKGQGAR 300 Query 301 VSVTEIDPINALQAMMEGFDVVTVEEAIGDADIVVTATGNKDIIMLEHIKAMKDHAILGN 360 VSVTEIDPINALQAMMEGFDVVTVEEAIGDADIVVTATGNKDIIMLEHIKAMKDHAILGN Sbjct 301 VSVTEIDPINALQAMMEGFDVVTVEEAIGDADIVVTATGNKDIIMLEHIKAMKDHAILGN 360 Query 361 IGHFDNEIDMAGLERSGATRVNVKPQVDLWTFGDTGRSIIVLSEGRLLNLGNATGHPSFV 420 IGHFDNEIDMAGLERSGATRVNVKPQVDLWTFGDTGRSIIVLSEGRLLNLGNATGHPSFV Sbjct 361 IGHFDNEIDMAGLERSGATRVNVKPQVDLWTFGDTGRSIIVLSEGRLLNLGNATGHPSFV 420 Query 421 MSNSFANQTIAQIELWTKNDEYDNEVYRLPKHLDEKVARIHVEALGGHLTKLTKEQAEYL 480 MSNSFANQTIAQIELWTKNDEYDNEVYRLPKHLDEKVARIHVEALGGHLTKLTKEQAEYL Sbjct 421 MSNSFANQTIAQIELWTKNDEYDNEVYRLPKHLDEKVARIHVEALGGHLTKLTKEQAEYL 480 Query 481 GVDVEGPYKPDHYRY 495 GVDVEGPYKPDHYRY Sbjct 481 GVDVEGPYKPDHYRY 495 >gi|240172609|ref|ZP_04751268.1| S-adenosyl-L-homocysteine hydrolase [Mycobacterium kansasii ATCC 12478] Length=492 Score = 977 bits (2525), Expect = 0.0, Method: Compositional matrix adjust. Identities = 470/489 (97%), Positives = 480/489 (99%), Gaps = 0/489 (0%) Query 7 TKNSLTPDVRNGIDFKIADLSLADFGRKELRIAEHEMPGLMSLRREYAEVQPLKGARISG 66 T+ SLTPDVRNGIDFKIADLSLADFGRKELRIAEHEMPGLMSLRREYAEVQPLKGARISG Sbjct 4 TETSLTPDVRNGIDFKIADLSLADFGRKELRIAEHEMPGLMSLRREYAEVQPLKGARISG 63 Query 67 SLHMTVQTAVLIETLTALGAEVRWASCNIFSTQDHAAAAVVVGPHGTPDEPKGVPVFAWK 126 SLHMTVQTAVLIETLT+LGAEVRWASCNIFSTQDHAAAAVVVGPHGTP+EPKGVPVFAWK Sbjct 64 SLHMTVQTAVLIETLTSLGAEVRWASCNIFSTQDHAAAAVVVGPHGTPEEPKGVPVFAWK 123 Query 127 GETLEEYWWAAEQMLTWPDPDKPANMILDDGGDATMLVLRGMQYEKAGVVPPAEEDDPAE 186 GETLEEYWWAAEQMLTWPDPDKPANMILDDGGDATMLVLRGMQYEKAGVVPPAEEDD AE Sbjct 124 GETLEEYWWAAEQMLTWPDPDKPANMILDDGGDATMLVLRGMQYEKAGVVPPAEEDDSAE 183 Query 187 WKVFLNLLRTRFETDKDKWTKIAESVKGVTEETTTGVLRLYQFAAAGDLAFPAINVNDSV 246 WKVFLNLLR RFE+DK KWTKIAESV+GVTEETTTGVLRLYQFAAAGDLAFPAINVNDSV Sbjct 184 WKVFLNLLRNRFESDKGKWTKIAESVQGVTEETTTGVLRLYQFAAAGDLAFPAINVNDSV 243 Query 247 TKSKFDNKYGTRHSLIDGINRGTDALIGGKKVLICGYGDVGKGCAEAMKGQGARVSVTEI 306 TKSKFDNKYGTRHSLIDGINRGTDALIGGKKVLICGYGDVGKGCAEAMKGQGARV VTEI Sbjct 244 TKSKFDNKYGTRHSLIDGINRGTDALIGGKKVLICGYGDVGKGCAEAMKGQGARVQVTEI 303 Query 307 DPINALQAMMEGFDVVTVEEAIGDADIVVTATGNKDIIMLEHIKAMKDHAILGNIGHFDN 366 DPINALQAMMEGFDVVTVE+AI DADIVVTATGNKDIIMLEHI+ MKDH+ILGNIGHFDN Sbjct 304 DPINALQAMMEGFDVVTVEDAIADADIVVTATGNKDIIMLEHIRQMKDHSILGNIGHFDN 363 Query 367 EIDMAGLERSGATRVNVKPQVDLWTFGDTGRSIIVLSEGRLLNLGNATGHPSFVMSNSFA 426 EIDMAGLERSGA+RVNVKPQVDLWTF DTGRSIIVLSEGRLLNLGNATGHPSFVMSNSFA Sbjct 364 EIDMAGLERSGASRVNVKPQVDLWTFPDTGRSIIVLSEGRLLNLGNATGHPSFVMSNSFA 423 Query 427 NQTIAQIELWTKNDEYDNEVYRLPKHLDEKVARIHVEALGGHLTKLTKEQAEYLGVDVEG 486 NQ IAQIELWTKNDEYDNEVYRLPKHLDEKVARIHVEALGGHLTKLTK+QAEYLGVDVEG Sbjct 424 NQVIAQIELWTKNDEYDNEVYRLPKHLDEKVARIHVEALGGHLTKLTKDQAEYLGVDVEG 483 Query 487 PYKPDHYRY 495 PYKPDHYRY Sbjct 484 PYKPDHYRY 492 >gi|183981317|ref|YP_001849608.1| adenosylhomocysteinase SahH [Mycobacterium marinum M] gi|226695340|sp|B2HEP6.1|SAHH_MYCMM RecName: Full=Adenosylhomocysteinase; AltName: Full=S-adenosyl-L-homocysteine hydrolase; Short=AdoHcyase gi|183174643|gb|ACC39753.1| adenosylhomocysteinase SahH [Mycobacterium marinum M] Length=492 Score = 973 bits (2516), Expect = 0.0, Method: Compositional matrix adjust. Identities = 468/489 (96%), Positives = 479/489 (98%), Gaps = 0/489 (0%) Query 7 TKNSLTPDVRNGIDFKIADLSLADFGRKELRIAEHEMPGLMSLRREYAEVQPLKGARISG 66 T+ SL+ D +NGIDFKIADLSLADFGRKELRIAEHEMPGLMSLRREYAEVQPLKGARISG Sbjct 4 TETSLSADTKNGIDFKIADLSLADFGRKELRIAEHEMPGLMSLRREYAEVQPLKGARISG 63 Query 67 SLHMTVQTAVLIETLTALGAEVRWASCNIFSTQDHAAAAVVVGPHGTPDEPKGVPVFAWK 126 SLHMTVQTAVLIETLTALGAEVRWASCNIFSTQDHAAAAVVVGPHGTP+EPKGVPVFAWK Sbjct 64 SLHMTVQTAVLIETLTALGAEVRWASCNIFSTQDHAAAAVVVGPHGTPEEPKGVPVFAWK 123 Query 127 GETLEEYWWAAEQMLTWPDPDKPANMILDDGGDATMLVLRGMQYEKAGVVPPAEEDDPAE 186 GE+LEEYWW AEQMLTWPD DKPANMILDDGGDATMLVLRGMQYEKAGVVPPAEEDD AE Sbjct 124 GESLEEYWWCAEQMLTWPDSDKPANMILDDGGDATMLVLRGMQYEKAGVVPPAEEDDSAE 183 Query 187 WKVFLNLLRTRFETDKDKWTKIAESVKGVTEETTTGVLRLYQFAAAGDLAFPAINVNDSV 246 WKVFL LLR+RFETDK KWTKIAESVKGVTEETTTGVLRLYQFAAAGDLAFPAINVNDSV Sbjct 184 WKVFLGLLRSRFETDKGKWTKIAESVKGVTEETTTGVLRLYQFAAAGDLAFPAINVNDSV 243 Query 247 TKSKFDNKYGTRHSLIDGINRGTDALIGGKKVLICGYGDVGKGCAEAMKGQGARVSVTEI 306 TKSKFDNKYGTRHSLIDGINRGTDALIGGKKVLICGYGDVGKGCAEAMKGQGARVSVTEI Sbjct 244 TKSKFDNKYGTRHSLIDGINRGTDALIGGKKVLICGYGDVGKGCAEAMKGQGARVSVTEI 303 Query 307 DPINALQAMMEGFDVVTVEEAIGDADIVVTATGNKDIIMLEHIKAMKDHAILGNIGHFDN 366 DPINALQAMMEGFDVVTVE+AIGDADIVVT+TGNKDIIMLEHIKAMKDH+ILGNIGHFDN Sbjct 304 DPINALQAMMEGFDVVTVEDAIGDADIVVTSTGNKDIIMLEHIKAMKDHSILGNIGHFDN 363 Query 367 EIDMAGLERSGATRVNVKPQVDLWTFGDTGRSIIVLSEGRLLNLGNATGHPSFVMSNSFA 426 EIDMAGLERSGATR N+KPQVDLWTFGDTGRSIIVLSEGRLLNLGNATGHPSFVMSNSFA Sbjct 364 EIDMAGLERSGATRTNIKPQVDLWTFGDTGRSIIVLSEGRLLNLGNATGHPSFVMSNSFA 423 Query 427 NQTIAQIELWTKNDEYDNEVYRLPKHLDEKVARIHVEALGGHLTKLTKEQAEYLGVDVEG 486 NQTIAQIELWTKNDEYDNEVYRLPKHLDEKVARIHVEALGG LTKLTK+QAEYLGVDVEG Sbjct 424 NQTIAQIELWTKNDEYDNEVYRLPKHLDEKVARIHVEALGGRLTKLTKDQAEYLGVDVEG 483 Query 487 PYKPDHYRY 495 PYKPDHYRY Sbjct 484 PYKPDHYRY 492 >gi|118618063|ref|YP_906395.1| S-adenosyl-L-homocysteine hydrolase [Mycobacterium ulcerans Agy99] gi|166233332|sp|A0PRF5.1|SAHH_MYCUA RecName: Full=Adenosylhomocysteinase; AltName: Full=S-adenosyl-L-homocysteine hydrolase; Short=AdoHcyase gi|118570173|gb|ABL04924.1| adenosylhomocysteinase SahH [Mycobacterium ulcerans Agy99] Length=492 Score = 971 bits (2509), Expect = 0.0, Method: Compositional matrix adjust. Identities = 467/489 (96%), Positives = 478/489 (98%), Gaps = 0/489 (0%) Query 7 TKNSLTPDVRNGIDFKIADLSLADFGRKELRIAEHEMPGLMSLRREYAEVQPLKGARISG 66 T+ SL+ D +NGIDFKIADLSLADFGRKELRIAEHEMPGLMSLRREYAEVQPLKGARISG Sbjct 4 TETSLSADTKNGIDFKIADLSLADFGRKELRIAEHEMPGLMSLRREYAEVQPLKGARISG 63 Query 67 SLHMTVQTAVLIETLTALGAEVRWASCNIFSTQDHAAAAVVVGPHGTPDEPKGVPVFAWK 126 SLHMTVQTAVLIETLTALGAEVRWASCNIFSTQDHAAAAVVVGPHGTP+EPKGVPVFAWK Sbjct 64 SLHMTVQTAVLIETLTALGAEVRWASCNIFSTQDHAAAAVVVGPHGTPEEPKGVPVFAWK 123 Query 127 GETLEEYWWAAEQMLTWPDPDKPANMILDDGGDATMLVLRGMQYEKAGVVPPAEEDDPAE 186 GE+LEEYWW AEQMLTWPD DKPANMILDDGGDATMLVLRGMQYEKAGVVPPAEEDD AE Sbjct 124 GESLEEYWWCAEQMLTWPDSDKPANMILDDGGDATMLVLRGMQYEKAGVVPPAEEDDSAE 183 Query 187 WKVFLNLLRTRFETDKDKWTKIAESVKGVTEETTTGVLRLYQFAAAGDLAFPAINVNDSV 246 WKVFL LLR+RFETDK KWTKIAESVKGVTEETTTGVLRLYQFA AGDLAFPAINVNDSV Sbjct 184 WKVFLGLLRSRFETDKGKWTKIAESVKGVTEETTTGVLRLYQFAEAGDLAFPAINVNDSV 243 Query 247 TKSKFDNKYGTRHSLIDGINRGTDALIGGKKVLICGYGDVGKGCAEAMKGQGARVSVTEI 306 TKSKFDNKYGTRHSLIDGINRGTDALIGGKKVLICGYGDVGKGCAEAMKGQGARVSVTEI Sbjct 244 TKSKFDNKYGTRHSLIDGINRGTDALIGGKKVLICGYGDVGKGCAEAMKGQGARVSVTEI 303 Query 307 DPINALQAMMEGFDVVTVEEAIGDADIVVTATGNKDIIMLEHIKAMKDHAILGNIGHFDN 366 DPINALQAMMEGFDVVTVE+AIGDADIVVT+TGNKDIIMLEHIKAMKDH+ILGNIGHFDN Sbjct 304 DPINALQAMMEGFDVVTVEDAIGDADIVVTSTGNKDIIMLEHIKAMKDHSILGNIGHFDN 363 Query 367 EIDMAGLERSGATRVNVKPQVDLWTFGDTGRSIIVLSEGRLLNLGNATGHPSFVMSNSFA 426 EIDMAGLERSGATR N+KPQVDLWTFGDTGRSIIVLSEGRLLNLGNATGHPSFVMSNSFA Sbjct 364 EIDMAGLERSGATRTNIKPQVDLWTFGDTGRSIIVLSEGRLLNLGNATGHPSFVMSNSFA 423 Query 427 NQTIAQIELWTKNDEYDNEVYRLPKHLDEKVARIHVEALGGHLTKLTKEQAEYLGVDVEG 486 NQTIAQIELWTKNDEYDNEVYRLPKHLDEKVARIHVEALGG LTKLTK+QAEYLGVDVEG Sbjct 424 NQTIAQIELWTKNDEYDNEVYRLPKHLDEKVARIHVEALGGRLTKLTKDQAEYLGVDVEG 483 Query 487 PYKPDHYRY 495 PYKPDHYRY Sbjct 484 PYKPDHYRY 492 >gi|15827332|ref|NP_301595.1| S-adenosyl-L-homocysteine hydrolase [Mycobacterium leprae TN] gi|221229810|ref|YP_002503226.1| S-adenosyl-L-homocysteine hydrolase [Mycobacterium leprae Br4923] gi|21362934|sp|Q9CCJ4.1|SAHH_MYCLE RecName: Full=Adenosylhomocysteinase; AltName: Full=S-adenosyl-L-homocysteine hydrolase; Short=AdoHcyase gi|254767539|sp|B8ZQE9.1|SAHH_MYCLB RecName: Full=Adenosylhomocysteinase; AltName: Full=S-adenosyl-L-homocysteine hydrolase; Short=AdoHcyase gi|13092881|emb|CAC30280.1| putative S-adenosyl-L-homocysteine hydrolase [Mycobacterium leprae] gi|219932917|emb|CAR70865.1| putative S-adenosyl-L-homocysteine hydrolase [Mycobacterium leprae Br4923] Length=492 Score = 938 bits (2425), Expect = 0.0, Method: Compositional matrix adjust. Identities = 447/489 (92%), Positives = 473/489 (97%), Gaps = 0/489 (0%) Query 7 TKNSLTPDVRNGIDFKIADLSLADFGRKELRIAEHEMPGLMSLRREYAEVQPLKGARISG 66 T+NSL PDVRNGIDFK+ADLSLA+FGRKEL +AE+EMPGLMSLR EYAEVQPLKGARISG Sbjct 4 TENSLMPDVRNGIDFKVADLSLANFGRKELDLAEYEMPGLMSLRHEYAEVQPLKGARISG 63 Query 67 SLHMTVQTAVLIETLTALGAEVRWASCNIFSTQDHAAAAVVVGPHGTPDEPKGVPVFAWK 126 SLHMTVQTAVLIETLTALGAEVRWASCNIFSTQDHAAAAVVVGP+GTP+EPKGVPVFAWK Sbjct 64 SLHMTVQTAVLIETLTALGAEVRWASCNIFSTQDHAAAAVVVGPYGTPEEPKGVPVFAWK 123 Query 127 GETLEEYWWAAEQMLTWPDPDKPANMILDDGGDATMLVLRGMQYEKAGVVPPAEEDDPAE 186 GETLEEYWWAAEQMLTWPDPDKP NMILDDGGDATMLVLRG+QYEKAGVVPPAE DD AE Sbjct 124 GETLEEYWWAAEQMLTWPDPDKPVNMILDDGGDATMLVLRGVQYEKAGVVPPAEVDDSAE 183 Query 187 WKVFLNLLRTRFETDKDKWTKIAESVKGVTEETTTGVLRLYQFAAAGDLAFPAINVNDSV 246 WKVFLNLLR RFETDK KWTKIA+SVKGVTEETTTGVLRLYQFAAAGDLAFPAINVNDSV Sbjct 184 WKVFLNLLRKRFETDKGKWTKIAKSVKGVTEETTTGVLRLYQFAAAGDLAFPAINVNDSV 243 Query 247 TKSKFDNKYGTRHSLIDGINRGTDALIGGKKVLICGYGDVGKGCAEAMKGQGARVSVTEI 306 TKSKFDNKYGTRHSLIDGINRGTD+LIGGK VLICGYGDVGKGCAEA KGQGARV++TEI Sbjct 244 TKSKFDNKYGTRHSLIDGINRGTDSLIGGKNVLICGYGDVGKGCAEAAKGQGARVTITEI 303 Query 307 DPINALQAMMEGFDVVTVEEAIGDADIVVTATGNKDIIMLEHIKAMKDHAILGNIGHFDN 366 DPINALQA+MEGFDV VE+ I D+DIVVTATGNKDII+LEH+KAMKDHAILGNIGHFDN Sbjct 304 DPINALQALMEGFDVKRVEDVIADSDIVVTATGNKDIILLEHMKAMKDHAILGNIGHFDN 363 Query 367 EIDMAGLERSGATRVNVKPQVDLWTFGDTGRSIIVLSEGRLLNLGNATGHPSFVMSNSFA 426 EIDMA LERSGATR+N+KPQVDLWTFGD+G+SIIVLSEGRLLNLGNATGHPSFVMSNSFA Sbjct 364 EIDMAALERSGATRLNIKPQVDLWTFGDSGKSIIVLSEGRLLNLGNATGHPSFVMSNSFA 423 Query 427 NQTIAQIELWTKNDEYDNEVYRLPKHLDEKVARIHVEALGGHLTKLTKEQAEYLGVDVEG 486 NQTIAQIELWTKND+YDNEVYRLPKHLDEKVAR+HVEALGG LTKLTK+QAEYLGVDV+G Sbjct 424 NQTIAQIELWTKNDDYDNEVYRLPKHLDEKVARVHVEALGGQLTKLTKDQAEYLGVDVDG 483 Query 487 PYKPDHYRY 495 P+KPDHYRY Sbjct 484 PFKPDHYRY 492 >gi|296168957|ref|ZP_06850626.1| adenosylhomocysteinase [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295896426|gb|EFG76079.1| adenosylhomocysteinase [Mycobacterium parascrofulaceum ATCC BAA-614] Length=493 Score = 905 bits (2340), Expect = 0.0, Method: Compositional matrix adjust. Identities = 428/489 (88%), Positives = 466/489 (96%), Gaps = 2/489 (0%) Query 7 TKNSLTPDVRNGIDFKIADLSLADFGRKELRIAEHEMPGLMSLRREYAEVQPLKGARISG 66 T++S T DVRNGIDFK+ADLSLA++GR+++ ++E EMPGLMSLRREYAEVQPLKGARISG Sbjct 7 TESSPTADVRNGIDFKVADLSLAEYGRRDIELSEQEMPGLMSLRREYAEVQPLKGARISG 66 Query 67 SLHMTVQTAVLIETLTALGAEVRWASCNIFSTQDHAAAAVVVGPHGTPDEPKGVPVFAWK 126 SLHMTVQTAVLIETL +LGA+VRWASCNIFSTQDHAAAAVVVGPHGTP+EPKGVPVFAWK Sbjct 67 SLHMTVQTAVLIETLVSLGAQVRWASCNIFSTQDHAAAAVVVGPHGTPEEPKGVPVFAWK 126 Query 127 GETLEEYWWAAEQMLTWPDPDKPANMILDDGGDATMLVLRGMQYEKAGVVPPAEEDDPAE 186 GETLEEYWWAAEQMLTWPD +PANMILDDGGDATMLVLRG QYEKAGVVPPAEEDDP+E Sbjct 127 GETLEEYWWAAEQMLTWPD--EPANMILDDGGDATMLVLRGAQYEKAGVVPPAEEDDPSE 184 Query 187 WKVFLNLLRTRFETDKDKWTKIAESVKGVTEETTTGVLRLYQFAAAGDLAFPAINVNDSV 246 WKVFL LLR RFETDKDKWTKI+ESVKGVTEETTTGVLRLYQFAAAGDLAFPAINVNDSV Sbjct 185 WKVFLELLRKRFETDKDKWTKISESVKGVTEETTTGVLRLYQFAAAGDLAFPAINVNDSV 244 Query 247 TKSKFDNKYGTRHSLIDGINRGTDALIGGKKVLICGYGDVGKGCAEAMKGQGARVSVTEI 306 TKSKFDNKYG RHSLIDGINRGTD LIGGKKVL+CGYGDVGKGCAE++KGQGARV VTEI Sbjct 245 TKSKFDNKYGCRHSLIDGINRGTDVLIGGKKVLVCGYGDVGKGCAESVKGQGARVVVTEI 304 Query 307 DPINALQAMMEGFDVVTVEEAIGDADIVVTATGNKDIIMLEHIKAMKDHAILGNIGHFDN 366 DPINALQA+MEG+DV TVE+AIG ADIV+TATGNKDII L+H+KAMKD+A+LGNIGHFDN Sbjct 305 DPINALQALMEGYDVETVEDAIGTADIVITATGNKDIITLDHMKAMKDYAVLGNIGHFDN 364 Query 367 EIDMAGLERSGATRVNVKPQVDLWTFGDTGRSIIVLSEGRLLNLGNATGHPSFVMSNSFA 426 EI +A LERSGAT+ N++PQVD+WTF D+G+SII+LSEGRLLNLGNATGHPSFVMSNSF+ Sbjct 365 EIQVAALERSGATKTNIRPQVDVWTFKDSGKSIILLSEGRLLNLGNATGHPSFVMSNSFS 424 Query 427 NQTIAQIELWTKNDEYDNEVYRLPKHLDEKVARIHVEALGGHLTKLTKEQAEYLGVDVEG 486 NQ IAQIELWTKNDEYDNEVYRLPKHLDEKVARIHVEALGG LTKLTKEQAEY+GVDV+G Sbjct 425 NQVIAQIELWTKNDEYDNEVYRLPKHLDEKVARIHVEALGGKLTKLTKEQAEYIGVDVDG 484 Query 487 PYKPDHYRY 495 PYK DHYRY Sbjct 485 PYKADHYRY 493 >gi|169630675|ref|YP_001704324.1| S-adenosyl-L-homocysteine hydrolase [Mycobacterium abscessus ATCC 19977] gi|169242642|emb|CAM63670.1| Adenosylhomocysteinase [Mycobacterium abscessus] Length=486 Score = 899 bits (2323), Expect = 0.0, Method: Compositional matrix adjust. Identities = 426/485 (88%), Positives = 464/485 (96%), Gaps = 2/485 (0%) Query 11 LTPDVRNGIDFKIADLSLADFGRKELRIAEHEMPGLMSLRREYAEVQPLKGARISGSLHM 70 L DVRNGI++K+ADLS A+FGRKE+R+AEHEMPGLM+LRREYAEV PLKGARISGSLHM Sbjct 4 LVADVRNGIEYKVADLSEAEFGRKEIRLAEHEMPGLMALRREYAEVLPLKGARISGSLHM 63 Query 71 TVQTAVLIETLTALGAEVRWASCNIFSTQDHAAAAVVVGPHGTPDEPKGVPVFAWKGETL 130 T+QTAVLIETL ALGAEVRWASCNIFSTQDHAAAAVVVGP+GTP+EP+G PVFAWKGETL Sbjct 64 TIQTAVLIETLVALGAEVRWASCNIFSTQDHAAAAVVVGPNGTPEEPQGTPVFAWKGETL 123 Query 131 EEYWWAAEQMLTWPDPDKPANMILDDGGDATMLVLRGMQYEKAGVVPPAEEDDPAEWKVF 190 EEYWWAAEQMLTWP+ +PANMILDDGGDATMLVLRG Q+E+AGVVPPA+++D AE+KVF Sbjct 124 EEYWWAAEQMLTWPN--EPANMILDDGGDATMLVLRGAQFEQAGVVPPADDNDSAEYKVF 181 Query 191 LNLLRTRFETDKDKWTKIAESVKGVTEETTTGVLRLYQFAAAGDLAFPAINVNDSVTKSK 250 LNLLR RFETDKDKWTKIAESV+GVTEETTTGVLRLYQFAAAG+LAFPAINVNDSVTKSK Sbjct 182 LNLLRERFETDKDKWTKIAESVQGVTEETTTGVLRLYQFAAAGELAFPAINVNDSVTKSK 241 Query 251 FDNKYGTRHSLIDGINRGTDALIGGKKVLICGYGDVGKGCAEAMKGQGARVSVTEIDPIN 310 FDNKYGTRHSL+DGINRGTD LIGGKKVLICGYGDVGKGCAE++ GQGARV VTEIDPIN Sbjct 242 FDNKYGTRHSLVDGINRGTDVLIGGKKVLICGYGDVGKGCAESLAGQGARVQVTEIDPIN 301 Query 311 ALQAMMEGFDVVTVEEAIGDADIVVTATGNKDIIMLEHIKAMKDHAILGNIGHFDNEIDM 370 ALQA+M+GFDVVTVE+AIGDADIVVTATGN DII+LEH+KAMKD AILGNIGHFDNEIDM Sbjct 302 ALQALMDGFDVVTVEQAIGDADIVVTATGNFDIILLEHMKAMKDQAILGNIGHFDNEIDM 361 Query 371 AGLERSGATRVNVKPQVDLWTFGDTGRSIIVLSEGRLLNLGNATGHPSFVMSNSFANQTI 430 A LE+SGA R+N+KPQVDLWTFGD+G+SIIVLSEGRLLNLGNATGHPSFVMSNSF+NQ I Sbjct 362 AALEKSGAVRLNIKPQVDLWTFGDSGKSIIVLSEGRLLNLGNATGHPSFVMSNSFSNQVI 421 Query 431 AQIELWTKNDEYDNEVYRLPKHLDEKVARIHVEALGGHLTKLTKEQAEYLGVDVEGPYKP 490 AQIELWTKNDEYDNEVYRL KHLDEKVARIHVEALGG LTKLTK+QAEY+GVDVEGPYKP Sbjct 422 AQIELWTKNDEYDNEVYRLAKHLDEKVARIHVEALGGTLTKLTKDQAEYIGVDVEGPYKP 481 Query 491 DHYRY 495 +HYRY Sbjct 482 EHYRY 486 >gi|145225295|ref|YP_001135973.1| S-adenosyl-L-homocysteine hydrolase [Mycobacterium gilvum PYR-GCK] gi|315445592|ref|YP_004078471.1| adenosylhomocysteinase [Mycobacterium sp. Spyr1] gi|145217781|gb|ABP47185.1| adenosylhomocysteinase [Mycobacterium gilvum PYR-GCK] gi|315263895|gb|ADU00637.1| adenosylhomocysteinase [Mycobacterium sp. Spyr1] Length=486 Score = 897 bits (2319), Expect = 0.0, Method: Compositional matrix adjust. Identities = 426/486 (88%), Positives = 463/486 (96%), Gaps = 2/486 (0%) Query 10 SLTPDVRNGIDFKIADLSLADFGRKELRIAEHEMPGLMSLRREYAEVQPLKGARISGSLH 69 +LT DVRNGID+K+ADLSLA+FGRKE+R+AEHEMPGLM LRREY +VQPLKGARISGSLH Sbjct 3 ALTADVRNGIDYKVADLSLAEFGRKEIRLAEHEMPGLMELRREYHDVQPLKGARISGSLH 62 Query 70 MTVQTAVLIETLTALGAEVRWASCNIFSTQDHAAAAVVVGPHGTPDEPKGVPVFAWKGET 129 MTVQTAVLIETLTALGAEVRWASCNIFSTQDHAAAAVVVGP+GTP+EPKG PVFAWKGET Sbjct 63 MTVQTAVLIETLTALGAEVRWASCNIFSTQDHAAAAVVVGPNGTPEEPKGTPVFAWKGET 122 Query 130 LEEYWWAAEQMLTWPDPDKPANMILDDGGDATMLVLRGMQYEKAGVVPPAEEDDPAEWKV 189 LEEYWWAAEQMLTWP +PANMILDDGGDATMLVLRG QYEKAGVVPPAE+DD AEWKV Sbjct 123 LEEYWWAAEQMLTWPG--EPANMILDDGGDATMLVLRGAQYEKAGVVPPAEDDDSAEWKV 180 Query 190 FLNLLRTRFETDKDKWTKIAESVKGVTEETTTGVLRLYQFAAAGDLAFPAINVNDSVTKS 249 FL L R +E KDKWTKIAESV+GVTEETTTGVLRLYQFAAAG+LAFPAINVNDSVTKS Sbjct 181 FLELCRKGYEQSKDKWTKIAESVQGVTEETTTGVLRLYQFAAAGELAFPAINVNDSVTKS 240 Query 250 KFDNKYGTRHSLIDGINRGTDALIGGKKVLICGYGDVGKGCAEAMKGQGARVSVTEIDPI 309 KFDNKYGTRHSLIDGINRGTDALIGGKKVLICGYGDVGKGCAE++ GQGARV VTEIDPI Sbjct 241 KFDNKYGTRHSLIDGINRGTDALIGGKKVLICGYGDVGKGCAESLAGQGARVQVTEIDPI 300 Query 310 NALQAMMEGFDVVTVEEAIGDADIVVTATGNKDIIMLEHIKAMKDHAILGNIGHFDNEID 369 NALQA+M+G+DVVTVE+AIGDADIV+T+TGNKDII L+H+KAMKDH+ILGNIGHFDNEID Sbjct 301 NALQALMDGYDVVTVEQAIGDADIVITSTGNKDIITLDHMKAMKDHSILGNIGHFDNEID 360 Query 370 MAGLERSGATRVNVKPQVDLWTFGDTGRSIIVLSEGRLLNLGNATGHPSFVMSNSFANQT 429 +A LERSGATR+N+KPQVD WTFG+TG+SII+LSEGRLLNLGNATGHPSFVMSNSF+NQ Sbjct 361 IAALERSGATRINIKPQVDEWTFGETGKSIILLSEGRLLNLGNATGHPSFVMSNSFSNQV 420 Query 430 IAQIELWTKNDEYDNEVYRLPKHLDEKVARIHVEALGGHLTKLTKEQAEYLGVDVEGPYK 489 IAQIELWTKNDEYDNEVYRL KHLDEKVA+IHVEALGG LT+LTK+QAEY+GVDVEGPYK Sbjct 421 IAQIELWTKNDEYDNEVYRLAKHLDEKVAKIHVEALGGTLTRLTKDQAEYIGVDVEGPYK 480 Query 490 PDHYRY 495 P+HYRY Sbjct 481 PEHYRY 486 >gi|54026586|ref|YP_120828.1| S-adenosyl-L-homocysteine hydrolase [Nocardia farcinica IFM 10152] gi|85543347|sp|Q5YQS7.1|SAHH_NOCFA RecName: Full=Adenosylhomocysteinase; AltName: Full=S-adenosyl-L-homocysteine hydrolase; Short=AdoHcyase gi|54018094|dbj|BAD59464.1| putative S-adenosyl-L-homocysteine hydrolase [Nocardia farcinica IFM 10152] Length=494 Score = 894 bits (2309), Expect = 0.0, Method: Compositional matrix adjust. Identities = 426/494 (87%), Positives = 464/494 (94%), Gaps = 2/494 (0%) Query 2 TGNLVTKNSLTPDVRNGIDFKIADLSLADFGRKELRIAEHEMPGLMSLRREYAEVQPLKG 61 T L + S TPDVRNGID+K+ADL+LA+FGRKE+R+AEHEMPGLM+LRREYA+VQPLKG Sbjct 3 TSELPARTSPTPDVRNGIDYKVADLTLAEFGRKEIRLAEHEMPGLMALRREYADVQPLKG 62 Query 62 ARISGSLHMTVQTAVLIETLTALGAEVRWASCNIFSTQDHAAAAVVVGPHGTPDEPKGVP 121 ARISGSLHMTVQTAVLIETLTALGA+VRWASCNIFSTQDHAAAAVVVGPHGT +EPKGV Sbjct 63 ARISGSLHMTVQTAVLIETLTALGAQVRWASCNIFSTQDHAAAAVVVGPHGTVEEPKGVS 122 Query 122 VFAWKGETLEEYWWAAEQMLTWPDPDKPANMILDDGGDATMLVLRGMQYEKAGVVPPAEE 181 VFAWKGETLEEYWWAAEQMLTWP +PANMILDDGGDATMLVLRG Q+EKAGVVPP + Sbjct 123 VFAWKGETLEEYWWAAEQMLTWPG--EPANMILDDGGDATMLVLRGAQFEKAGVVPPEDA 180 Query 182 DDPAEWKVFLNLLRTRFETDKDKWTKIAESVKGVTEETTTGVLRLYQFAAAGDLAFPAIN 241 D AE+KVFLNLLR RFETD+ KWT IAESV+GVTEETTTGVLRLYQFAAAG+L FPAIN Sbjct 181 DHSAEYKVFLNLLRERFETDRGKWTAIAESVRGVTEETTTGVLRLYQFAAAGELVFPAIN 240 Query 242 VNDSVTKSKFDNKYGTRHSLIDGINRGTDALIGGKKVLICGYGDVGKGCAEAMKGQGARV 301 VNDSVTKSKFDNKYGTRHSLIDGINRGTD LIGGKKVLICGYGDVGKGCAE++ GQGARV Sbjct 241 VNDSVTKSKFDNKYGTRHSLIDGINRGTDVLIGGKKVLICGYGDVGKGCAESLAGQGARV 300 Query 302 SVTEIDPINALQAMMEGFDVVTVEEAIGDADIVVTATGNKDIIMLEHIKAMKDHAILGNI 361 VTEIDPINALQA+M+G+DVVTVE+AIG+ADIV+TATGNKDII L+H+KAMKD AILGNI Sbjct 301 QVTEIDPINALQALMDGYDVVTVEQAIGEADIVITATGNKDIITLDHMKAMKDQAILGNI 360 Query 362 GHFDNEIDMAGLERSGATRVNVKPQVDLWTFGDTGRSIIVLSEGRLLNLGNATGHPSFVM 421 GHFDNEIDMA LERSGATR+ +KPQVDLWTFG++G+SIIVLSEGRLLNLGNATGHPSFVM Sbjct 361 GHFDNEIDMAALERSGATRLTIKPQVDLWTFGESGKSIIVLSEGRLLNLGNATGHPSFVM 420 Query 422 SNSFANQTIAQIELWTKNDEYDNEVYRLPKHLDEKVARIHVEALGGHLTKLTKEQAEYLG 481 SNSF+NQ IAQIELWTK +EYDNEVYRLPKHLDEKVARIHVEALGG LTKLTK+QAEY+G Sbjct 421 SNSFSNQVIAQIELWTKPEEYDNEVYRLPKHLDEKVARIHVEALGGTLTKLTKDQAEYIG 480 Query 482 VDVEGPYKPDHYRY 495 VDVEGPYKP+HYRY Sbjct 481 VDVEGPYKPEHYRY 494 >gi|120402746|ref|YP_952575.1| S-adenosyl-L-homocysteine hydrolase [Mycobacterium vanbaalenii PYR-1] gi|119955564|gb|ABM12569.1| adenosylhomocysteinase [Mycobacterium vanbaalenii PYR-1] Length=485 Score = 890 bits (2301), Expect = 0.0, Method: Compositional matrix adjust. Identities = 426/486 (88%), Positives = 460/486 (95%), Gaps = 3/486 (0%) Query 10 SLTPDVRNGIDFKIADLSLADFGRKELRIAEHEMPGLMSLRREYAEVQPLKGARISGSLH 69 +LT DVRNG+D+K+ADLSLA+FGRKE+R+AEHEMPGLM+LR EYAEVQPLKGARISGSLH Sbjct 3 ALTADVRNGLDYKVADLSLAEFGRKEIRLAEHEMPGLMALRHEYAEVQPLKGARISGSLH 62 Query 70 MTVQTAVLIETLTALGAEVRWASCNIFSTQDHAAAAVVVGPHGTPDEPKGVPVFAWKGET 129 MTVQTAVLIETL ALGAEVRWASCNIFSTQDHAAAAVVVGP+GTP+EPKG PVFAWKGET Sbjct 63 MTVQTAVLIETLVALGAEVRWASCNIFSTQDHAAAAVVVGPNGTPEEPKGTPVFAWKGET 122 Query 130 LEEYWWAAEQMLTWPDPDKPANMILDDGGDATMLVLRGMQYEKAGVVPPAEEDDPAEWKV 189 LEEYWWAAEQMLTW KPANMILDDGGDATMLVLRG QYEKAGVVPPAE+DDPAEWKV Sbjct 123 LEEYWWAAEQMLTWEG--KPANMILDDGGDATMLVLRGAQYEKAGVVPPAEDDDPAEWKV 180 Query 190 FLNLLRTRFETDKDKWTKIAESVKGVTEETTTGVLRLYQFAAAGDLAFPAINVNDSVTKS 249 FL+L+R FE DK KWTKIAESVKGVTEETTTGVLRLYQFAAAG+LAFPAINVNDSVTKS Sbjct 181 FLSLVREGFEKDKTKWTKIAESVKGVTEETTTGVLRLYQFAAAGELAFPAINVNDSVTKS 240 Query 250 KFDNKYGTRHSLIDGINRGTDALIGGKKVLICGYGDVGKGCAEAMKGQGARVSVTEIDPI 309 KFDNKYGTRHSLIDGINRGTD LIGGKKVLICGYGDVGKGCAE++ GQGARV+VTEIDPI Sbjct 241 KFDNKYGTRHSLIDGINRGTDVLIGGKKVLICGYGDVGKGCAESLAGQGARVAVTEIDPI 300 Query 310 NALQAMMEGFDVVTVEEAIGDADIVVTATGNKDIIMLEHIKAMKDHAILGNIGHFDNEID 369 NALQA+M+GFDVVTVE+ I +ADIV+T+TGNKDII L+H+KAMK+ AILGNIGHFDNEID Sbjct 301 NALQALMDGFDVVTVEQGIAEADIVITSTGNKDIITLDHMKAMKNQAILGNIGHFDNEID 360 Query 370 MAGLERSGATRVNVKPQVDLWTFGDTGRSIIVLSEGRLLNLGNATGHPSFVMSNSFANQT 429 MA LERSGATR+N+KPQVD W F ++G+SIIVLSEGRLLNLGNATGHPSFVMSNSF+NQ Sbjct 361 MAALERSGATRINIKPQVDQWIF-ESGKSIIVLSEGRLLNLGNATGHPSFVMSNSFSNQV 419 Query 430 IAQIELWTKNDEYDNEVYRLPKHLDEKVARIHVEALGGHLTKLTKEQAEYLGVDVEGPYK 489 IAQIELWTKNDEYDNEVYRL KHLDEKVARIHVEALGG LTKLTKEQAEY+GVDVEGPYK Sbjct 420 IAQIELWTKNDEYDNEVYRLAKHLDEKVARIHVEALGGTLTKLTKEQAEYIGVDVEGPYK 479 Query 490 PDHYRY 495 P+HYRY Sbjct 480 PEHYRY 485 >gi|126433974|ref|YP_001069665.1| S-adenosyl-L-homocysteine hydrolase [Mycobacterium sp. JLS] gi|166233329|sp|A3PW97.1|SAHH_MYCSJ RecName: Full=Adenosylhomocysteinase; AltName: Full=S-adenosyl-L-homocysteine hydrolase; Short=AdoHcyase gi|126233774|gb|ABN97174.1| adenosylhomocysteinase [Mycobacterium sp. JLS] Length=489 Score = 889 bits (2296), Expect = 0.0, Method: Compositional matrix adjust. Identities = 427/489 (88%), Positives = 457/489 (94%), Gaps = 3/489 (0%) Query 7 TKNSLTPDVRNGIDFKIADLSLADFGRKELRIAEHEMPGLMSLRREYAEVQPLKGARISG 66 T+ LT + RNGID+K+ADLSLA+FGRKE+R+AEHEMPGLM+LRREYAEV PLKGARISG Sbjct 4 TEQRLTVESRNGIDYKVADLSLAEFGRKEIRLAEHEMPGLMALRREYAEVAPLKGARISG 63 Query 67 SLHMTVQTAVLIETLTALGAEVRWASCNIFSTQDHAAAAVVVGPHGTPDEPKGVPVFAWK 126 SLHMTVQTAVLIETL +LGAEVRWASCNIFSTQDHAAAAVVVGPHGTP+EPKG PVFAWK Sbjct 64 SLHMTVQTAVLIETLVSLGAEVRWASCNIFSTQDHAAAAVVVGPHGTPEEPKGTPVFAWK 123 Query 127 GETLEEYWWAAEQMLTWPDPDKPANMILDDGGDATMLVLRGMQYEKAGVVPPAEEDDPAE 186 GETLEEYWWAAEQMLTWP +PANMILDDGGDATMLVLRG Q+EKAGVVPPAE+DD AE Sbjct 124 GETLEEYWWAAEQMLTWPG--EPANMILDDGGDATMLVLRGAQFEKAGVVPPAEDDDSAE 181 Query 187 WKVFLNLLRTRFETDKDKWTKIAESVKGVTEETTTGVLRLYQFAAAGDLAFPAINVNDSV 246 +KVFLNLLR RFETDK KWTKIAESVKGVTEETTTGVLRLYQF AAG+L FPAINVNDSV Sbjct 182 YKVFLNLLRERFETDKTKWTKIAESVKGVTEETTTGVLRLYQFEAAGELPFPAINVNDSV 241 Query 247 TKSKFDNKYGTRHSLIDGINRGTDALIGGKKVLICGYGDVGKGCAEAMKGQGARVSVTEI 306 TKSKFDNKYGTRHSLIDGINRGTD LIGGKKVLICGYGDVGKGCAE++ GQGARV VTEI Sbjct 242 TKSKFDNKYGTRHSLIDGINRGTDVLIGGKKVLICGYGDVGKGCAESLAGQGARVQVTEI 301 Query 307 DPINALQAMMEGFDVVTVEEAIGDADIVVTATGNKDIIMLEHIKAMKDHAILGNIGHFDN 366 DPINALQA+M+GFDVVTVE+AIG ADIV+T+TGNKDII L+H+KAMKD AILGNIGHFDN Sbjct 302 DPINALQALMDGFDVVTVEQAIGSADIVITSTGNKDIITLDHMKAMKDKAILGNIGHFDN 361 Query 367 EIDMAGLERSGATRVNVKPQVDLWTFGDTGRSIIVLSEGRLLNLGNATGHPSFVMSNSFA 426 EIDMA LERSGATR+N+KPQVD WTF D G SI+VLSEGRLLNLGNATGHPSFVMSNSF+ Sbjct 362 EIDMAALERSGATRINIKPQVDEWTF-DDGHSIVVLSEGRLLNLGNATGHPSFVMSNSFS 420 Query 427 NQTIAQIELWTKNDEYDNEVYRLPKHLDEKVARIHVEALGGHLTKLTKEQAEYLGVDVEG 486 NQ IAQIELWTKNDEYDN VYRL KHLDEKVARIHVEALGG LTKLTKEQAEY+ VDVEG Sbjct 421 NQVIAQIELWTKNDEYDNAVYRLAKHLDEKVARIHVEALGGTLTKLTKEQAEYINVDVEG 480 Query 487 PYKPDHYRY 495 PYKP+HYRY Sbjct 481 PYKPEHYRY 489 >gi|254822995|ref|ZP_05227996.1| S-adenosyl-L-homocysteine hydrolase [Mycobacterium intracellulare ATCC 13950] Length=490 Score = 888 bits (2294), Expect = 0.0, Method: Compositional matrix adjust. Identities = 423/489 (87%), Positives = 459/489 (94%), Gaps = 2/489 (0%) Query 7 TKNSLTPDVRNGIDFKIADLSLADFGRKELRIAEHEMPGLMSLRREYAEVQPLKGARISG 66 T+N+LTPDVRNGIDFK+ADLSLAD+GR+++ ++E EMPGLMSLRREY +VQPLKGARISG Sbjct 4 TENALTPDVRNGIDFKVADLSLADYGRRDIELSEQEMPGLMSLRREYHDVQPLKGARISG 63 Query 67 SLHMTVQTAVLIETLTALGAEVRWASCNIFSTQDHAAAAVVVGPHGTPDEPKGVPVFAWK 126 SLHMTVQTAVLIETL ALGAEVRWASCNIFSTQDHAAAAVVVGPHGTP+EPKGVPV+AWK Sbjct 64 SLHMTVQTAVLIETLVALGAEVRWASCNIFSTQDHAAAAVVVGPHGTPEEPKGVPVYAWK 123 Query 127 GETLEEYWWAAEQMLTWPDPDKPANMILDDGGDATMLVLRGMQYEKAGVVPPAEEDDPAE 186 GETLEEYWWAAEQ+LTWPD +PANMILDDGGDATMLVLRG QYEKAGVVPP +EDD E Sbjct 124 GETLEEYWWAAEQVLTWPD--EPANMILDDGGDATMLVLRGAQYEKAGVVPPDDEDDSTE 181 Query 187 WKVFLNLLRTRFETDKDKWTKIAESVKGVTEETTTGVLRLYQFAAAGDLAFPAINVNDSV 246 +VFLNLLR RFETDKDKWTKIA S+KGV+EETTTGVLRLYQFAAAGDLAFPAINVNDSV Sbjct 182 HRVFLNLLRKRFETDKDKWTKIAASIKGVSEETTTGVLRLYQFAAAGDLAFPAINVNDSV 241 Query 247 TKSKFDNKYGTRHSLIDGINRGTDALIGGKKVLICGYGDVGKGCAEAMKGQGARVSVTEI 306 TKSKFDNKYG RHSLIDGINRGTD LIGGKKVLICGYGDVGKG AE++ GQGARV+VTEI Sbjct 242 TKSKFDNKYGCRHSLIDGINRGTDVLIGGKKVLICGYGDVGKGSAESVAGQGARVTVTEI 301 Query 307 DPINALQAMMEGFDVVTVEEAIGDADIVVTATGNKDIIMLEHIKAMKDHAILGNIGHFDN 366 DPINALQA+MEGFDV VE+ IG+ADI++T TGNKDII LEH+KAMKD AILGNIGHFDN Sbjct 302 DPINALQALMEGFDVKRVEDVIGEADIIITTTGNKDIITLEHMKAMKDKAILGNIGHFDN 361 Query 367 EIDMAGLERSGATRVNVKPQVDLWTFGDTGRSIIVLSEGRLLNLGNATGHPSFVMSNSFA 426 EI +A LE+SGAT+ N++PQVDLWTF DTG+SIIVLSEGRLLNLGNATGHPSFVMSNSF+ Sbjct 362 EIQIARLEKSGATKTNIRPQVDLWTFPDTGKSIIVLSEGRLLNLGNATGHPSFVMSNSFS 421 Query 427 NQTIAQIELWTKNDEYDNEVYRLPKHLDEKVARIHVEALGGHLTKLTKEQAEYLGVDVEG 486 NQ IAQIELWTKNDEYDNEVYRLPKHLDEKVARIHVEALGG LTKLTKEQAEY+GVDV+G Sbjct 422 NQVIAQIELWTKNDEYDNEVYRLPKHLDEKVARIHVEALGGKLTKLTKEQAEYIGVDVDG 481 Query 487 PYKPDHYRY 495 PYK DHYRY Sbjct 482 PYKADHYRY 490 >gi|342861451|ref|ZP_08718098.1| S-adenosyl-L-homocysteine hydrolase [Mycobacterium colombiense CECT 3035] gi|342130940|gb|EGT84229.1| S-adenosyl-L-homocysteine hydrolase [Mycobacterium colombiense CECT 3035] Length=490 Score = 888 bits (2294), Expect = 0.0, Method: Compositional matrix adjust. Identities = 425/489 (87%), Positives = 459/489 (94%), Gaps = 2/489 (0%) Query 7 TKNSLTPDVRNGIDFKIADLSLADFGRKELRIAEHEMPGLMSLRREYAEVQPLKGARISG 66 T+N+LTPDVRNGIDFK+ADLSLAD+GR+++ ++E EMPGLMSLRREY +VQPLKGARISG Sbjct 4 TENALTPDVRNGIDFKVADLSLADYGRRDIELSEQEMPGLMSLRREYHDVQPLKGARISG 63 Query 67 SLHMTVQTAVLIETLTALGAEVRWASCNIFSTQDHAAAAVVVGPHGTPDEPKGVPVFAWK 126 SLHMTVQTAVLIETL ALGAEVRWASCNIFSTQDHAAAAVVVGPHGTP+EPKGVPV+AWK Sbjct 64 SLHMTVQTAVLIETLVALGAEVRWASCNIFSTQDHAAAAVVVGPHGTPEEPKGVPVYAWK 123 Query 127 GETLEEYWWAAEQMLTWPDPDKPANMILDDGGDATMLVLRGMQYEKAGVVPPAEEDDPAE 186 GETLEEYWWAAEQ+LTWP +PANMILDDGGDATMLVLRG QYEKAGVVPP EEDD E Sbjct 124 GETLEEYWWAAEQVLTWPG--EPANMILDDGGDATMLVLRGAQYEKAGVVPPDEEDDSTE 181 Query 187 WKVFLNLLRTRFETDKDKWTKIAESVKGVTEETTTGVLRLYQFAAAGDLAFPAINVNDSV 246 +VFLNLLR RFETDKDKWTKIA S+KGV+EETTTGVLRLYQFAAAGDLAFPAINVNDSV Sbjct 182 HRVFLNLLRKRFETDKDKWTKIAASIKGVSEETTTGVLRLYQFAAAGDLAFPAINVNDSV 241 Query 247 TKSKFDNKYGTRHSLIDGINRGTDALIGGKKVLICGYGDVGKGCAEAMKGQGARVSVTEI 306 TKSKFDNKYG RHSLIDGINRGTD LIGGKKVLICGYGDVGKG AE++ GQGARV+VTEI Sbjct 242 TKSKFDNKYGCRHSLIDGINRGTDVLIGGKKVLICGYGDVGKGSAESVAGQGARVTVTEI 301 Query 307 DPINALQAMMEGFDVVTVEEAIGDADIVVTATGNKDIIMLEHIKAMKDHAILGNIGHFDN 366 DPINALQA+MEGFDV VE+ IG+ADIV+T TGNKDII LEH+KAMKD AILGNIGHFDN Sbjct 302 DPINALQALMEGFDVKRVEDVIGEADIVITTTGNKDIITLEHMKAMKDKAILGNIGHFDN 361 Query 367 EIDMAGLERSGATRVNVKPQVDLWTFGDTGRSIIVLSEGRLLNLGNATGHPSFVMSNSFA 426 EI +A LERSGAT+VN++PQVDLWTF DTG+SII+LSEGRLLNLGNATGHPSFVMSNSF+ Sbjct 362 EIQVARLERSGATKVNIRPQVDLWTFPDTGKSIILLSEGRLLNLGNATGHPSFVMSNSFS 421 Query 427 NQTIAQIELWTKNDEYDNEVYRLPKHLDEKVARIHVEALGGHLTKLTKEQAEYLGVDVEG 486 NQ IAQIELWTKNDEYDNEVYRLPKHLDEKVARIHVEALGG LTKLTKEQAEY+GVDV+G Sbjct 422 NQVIAQIELWTKNDEYDNEVYRLPKHLDEKVARIHVEALGGVLTKLTKEQAEYIGVDVDG 481 Query 487 PYKPDHYRY 495 PYK DHYRY Sbjct 482 PYKADHYRY 490 >gi|108798307|ref|YP_638504.1| S-adenosyl-L-homocysteine hydrolase [Mycobacterium sp. MCS] gi|119867404|ref|YP_937356.1| S-adenosyl-L-homocysteine hydrolase [Mycobacterium sp. KMS] gi|123179239|sp|Q1BCD6.1|SAHH_MYCSS RecName: Full=Adenosylhomocysteinase; AltName: Full=S-adenosyl-L-homocysteine hydrolase; Short=AdoHcyase gi|166233330|sp|A1UCK8.1|SAHH_MYCSK RecName: Full=Adenosylhomocysteinase; AltName: Full=S-adenosyl-L-homocysteine hydrolase; Short=AdoHcyase gi|108768726|gb|ABG07448.1| adenosylhomocysteinase [Mycobacterium sp. MCS] gi|119693493|gb|ABL90566.1| adenosylhomocysteinase [Mycobacterium sp. KMS] Length=489 Score = 887 bits (2293), Expect = 0.0, Method: Compositional matrix adjust. Identities = 426/489 (88%), Positives = 457/489 (94%), Gaps = 3/489 (0%) Query 7 TKNSLTPDVRNGIDFKIADLSLADFGRKELRIAEHEMPGLMSLRREYAEVQPLKGARISG 66 T+ LT + RNGID+K+ADLSLA+FGRKE+R+AEHEMPGLM+LRREYAEV PLKGARISG Sbjct 4 TEQRLTVESRNGIDYKVADLSLAEFGRKEIRLAEHEMPGLMALRREYAEVAPLKGARISG 63 Query 67 SLHMTVQTAVLIETLTALGAEVRWASCNIFSTQDHAAAAVVVGPHGTPDEPKGVPVFAWK 126 SLHMTVQTAVLIETL +LGAEVRWASCNIFSTQDHAAAAVVVGPHGTP+EPKG PVFAWK Sbjct 64 SLHMTVQTAVLIETLVSLGAEVRWASCNIFSTQDHAAAAVVVGPHGTPEEPKGTPVFAWK 123 Query 127 GETLEEYWWAAEQMLTWPDPDKPANMILDDGGDATMLVLRGMQYEKAGVVPPAEEDDPAE 186 GETLEEYWWAAEQMLTWP +PANMILDDGGDATMLVLRG Q+EKAGVVPPAE+DD AE Sbjct 124 GETLEEYWWAAEQMLTWPG--EPANMILDDGGDATMLVLRGAQFEKAGVVPPAEDDDSAE 181 Query 187 WKVFLNLLRTRFETDKDKWTKIAESVKGVTEETTTGVLRLYQFAAAGDLAFPAINVNDSV 246 +KVFLNLLR RFETDK KWTKIAESVKGVTEETTTGVLRLYQF AAG+L FPAINVNDSV Sbjct 182 YKVFLNLLRERFETDKTKWTKIAESVKGVTEETTTGVLRLYQFEAAGELPFPAINVNDSV 241 Query 247 TKSKFDNKYGTRHSLIDGINRGTDALIGGKKVLICGYGDVGKGCAEAMKGQGARVSVTEI 306 TKSKFDNKYGTRHSLIDGINRGTD LIGGKKVLICGYGDVGKGCAE++ GQGARV VTEI Sbjct 242 TKSKFDNKYGTRHSLIDGINRGTDVLIGGKKVLICGYGDVGKGCAESLAGQGARVQVTEI 301 Query 307 DPINALQAMMEGFDVVTVEEAIGDADIVVTATGNKDIIMLEHIKAMKDHAILGNIGHFDN 366 DPINALQA+M+GFDVVTVE+AIG ADIV+T+TGNKDII L+H+KAMKD AILGNIGHFDN Sbjct 302 DPINALQALMDGFDVVTVEQAIGSADIVITSTGNKDIITLDHMKAMKDKAILGNIGHFDN 361 Query 367 EIDMAGLERSGATRVNVKPQVDLWTFGDTGRSIIVLSEGRLLNLGNATGHPSFVMSNSFA 426 EIDMA LERSGATR+N+KPQVD WTF D G SI++LSEGRLLNLGNATGHPSFVMSNSF+ Sbjct 362 EIDMAALERSGATRINIKPQVDEWTF-DDGHSIVLLSEGRLLNLGNATGHPSFVMSNSFS 420 Query 427 NQTIAQIELWTKNDEYDNEVYRLPKHLDEKVARIHVEALGGHLTKLTKEQAEYLGVDVEG 486 NQ IAQIELWTKNDEYDN VYRL KHLDEKVARIHVEALGG LTKLTKEQAEY+ VDVEG Sbjct 421 NQVIAQIELWTKNDEYDNAVYRLAKHLDEKVARIHVEALGGTLTKLTKEQAEYINVDVEG 480 Query 487 PYKPDHYRY 495 PYKP+HYRY Sbjct 481 PYKPEHYRY 489 >gi|302595893|sp|A4ZHR8.1|SAHH_MYCS2 RecName: Full=Adenosylhomocysteinase; AltName: Full=S-adenosyl-L-homocysteine hydrolase; Short=AdoHcyase gi|116266924|gb|ABJ96308.1| putative adenosylhomocysteinase [Mycobacterium smegmatis str. MC2 155] Length=485 Score = 885 bits (2287), Expect = 0.0, Method: Compositional matrix adjust. Identities = 425/485 (88%), Positives = 457/485 (95%), Gaps = 3/485 (0%) Query 11 LTPDVRNGIDFKIADLSLADFGRKELRIAEHEMPGLMSLRREYAEVQPLKGARISGSLHM 70 L DVRNGID+K+ADLSLADFGRKE+R+AEHEMPGLM+LRREY +VQPLKGARISGSLHM Sbjct 4 LKADVRNGIDYKVADLSLADFGRKEIRLAEHEMPGLMALRREYHDVQPLKGARISGSLHM 63 Query 71 TVQTAVLIETLTALGAEVRWASCNIFSTQDHAAAAVVVGPHGTPDEPKGVPVFAWKGETL 130 TVQTAVLIETL +LGAEVRWASCNIFSTQDHAAAAVVVGP+GTP+EPKGV VFAWKGETL Sbjct 64 TVQTAVLIETLVSLGAEVRWASCNIFSTQDHAAAAVVVGPNGTPEEPKGVSVFAWKGETL 123 Query 131 EEYWWAAEQMLTWPDPDKPANMILDDGGDATMLVLRGMQYEKAGVVPPAEEDDPAEWKVF 190 EEYWWAAEQMLTW +PANMILDDGGDATM+VLRG QYEKAGVVPPAE+DDPAEWKVF Sbjct 124 EEYWWAAEQMLTWDG--EPANMILDDGGDATMMVLRGAQYEKAGVVPPAEDDDPAEWKVF 181 Query 191 LNLLRTRFETDKDKWTKIAESVKGVTEETTTGVLRLYQFAAAGDLAFPAINVNDSVTKSK 250 L +LR RFE DK KWTKIAESVKGVTEETTTGVLRLYQFAAAG+LAFPAINVNDSVTKSK Sbjct 182 LGVLRERFEQDKTKWTKIAESVKGVTEETTTGVLRLYQFAAAGELAFPAINVNDSVTKSK 241 Query 251 FDNKYGTRHSLIDGINRGTDALIGGKKVLICGYGDVGKGCAEAMKGQGARVSVTEIDPIN 310 FDNKYGTRHSLIDGINRGTD LIGGKKVLICGYGDVGKGCAE++ GQGARVSVTEIDPIN Sbjct 242 FDNKYGTRHSLIDGINRGTDVLIGGKKVLICGYGDVGKGCAESLAGQGARVSVTEIDPIN 301 Query 311 ALQAMMEGFDVVTVEEAIGDADIVVTATGNKDIIMLEHIKAMKDHAILGNIGHFDNEIDM 370 ALQA+M+GFDV TVEEAIG+ADIV+TATGNKDII L+H+KAMK+ AILGNIGHFDNEIDM Sbjct 302 ALQALMDGFDVRTVEEAIGEADIVITATGNKDIITLDHMKAMKNQAILGNIGHFDNEIDM 361 Query 371 AGLERSGATRVNVKPQVDLWTFGDTGRSIIVLSEGRLLNLGNATGHPSFVMSNSFANQTI 430 A LERSGA ++N+KPQVD W F D G+SIIVLSEGRLLNLGNATGHPSFVMSNSF+NQ I Sbjct 362 AALERSGAKKINIKPQVDQWIF-DDGKSIIVLSEGRLLNLGNATGHPSFVMSNSFSNQVI 420 Query 431 AQIELWTKNDEYDNEVYRLPKHLDEKVARIHVEALGGHLTKLTKEQAEYLGVDVEGPYKP 490 AQIELWTKNDEYDNEVYRL KHLDEKVARIHVEALGG LTKL+K+QAEY+GVDVEGPYKP Sbjct 421 AQIELWTKNDEYDNEVYRLAKHLDEKVARIHVEALGGTLTKLSKDQAEYIGVDVEGPYKP 480 Query 491 DHYRY 495 +HYRY Sbjct 481 EHYRY 485 >gi|343927674|ref|ZP_08767142.1| adenosylhomocysteinase [Gordonia alkanivorans NBRC 16433] gi|343762315|dbj|GAA14068.1| adenosylhomocysteinase [Gordonia alkanivorans NBRC 16433] Length=491 Score = 883 bits (2281), Expect = 0.0, Method: Compositional matrix adjust. Identities = 421/488 (87%), Positives = 455/488 (94%), Gaps = 1/488 (0%) Query 8 KNSLTPDVRNGIDFKIADLSLADFGRKELRIAEHEMPGLMSLRREYAEVQPLKGARISGS 67 ++ L D RNGID+K+ADLSLADFGRKE+ +AEHEMPGLM LRRE A+V PLKGARISGS Sbjct 5 QDELKADSRNGIDYKVADLSLADFGRKEIELAEHEMPGLMELRRENADVLPLKGARISGS 64 Query 68 LHMTVQTAVLIETLTALGAEVRWASCNIFSTQDHAAAAVVVGPHGTPDEPKGVPVFAWKG 127 LHMTVQTAVLIETL ALGAEVRWASCNIFSTQDHAAAAVVVGPHGTPDEPKGVPVFAWKG Sbjct 65 LHMTVQTAVLIETLVALGAEVRWASCNIFSTQDHAAAAVVVGPHGTPDEPKGVPVFAWKG 124 Query 128 ETLEEYWWAAEQMLTWPDPDKPANMILDDGGDATMLVLRGMQYEKAGVVPPAEEDDPAEW 187 ETLEEYWWAAEQMLTWP+ DKPANMILDDGGDATMLVLRG ++EKAGVVPP E+D PAE+ Sbjct 125 ETLEEYWWAAEQMLTWPEADKPANMILDDGGDATMLVLRGAEFEKAGVVPPTEDDHPAEY 184 Query 188 KVFLNLLRTRFETDKDKWTKIAESVKGVTEETTTGVLRLYQFAAAGDLAFPAINVNDSVT 247 KVFL LLR RFETDK+KWT IAESV+GVTEETTTGVLRLYQFAAAG+L FPAINVNDSVT Sbjct 185 KVFLELLRERFETDKNKWTTIAESVQGVTEETTTGVLRLYQFAAAGELTFPAINVNDSVT 244 Query 248 KSKFDNKYGTRHSLIDGINRGTDALIGGKKVLICGYGDVGKGCAEAMKGQGARVSVTEID 307 KSKFDNKYGTRHSLIDGINRGTD LIGGKKVLICGYGDVGKGCAE++ GQGARV VTEID Sbjct 245 KSKFDNKYGTRHSLIDGINRGTDVLIGGKKVLICGYGDVGKGCAESLAGQGARVQVTEID 304 Query 308 PINALQAMMEGFDVVTVEEAIGDADIVVTATGNKDIIMLEHIKAMKDHAILGNIGHFDNE 367 PINALQA+M+G+DVVTVE+AIG+ADIV+T+TGN II L+H++ MK AILGNIGHFDNE Sbjct 305 PINALQALMDGYDVVTVEDAIGNADIVITSTGNLGIITLDHMRQMKHQAILGNIGHFDNE 364 Query 368 IDMAGLERSGATRVNVKPQVDLWTFGDTGRSIIVLSEGRLLNLGNATGHPSFVMSNSFAN 427 IDMAGLERSGA R+ VKPQVD W F ++G+SIIVLSEGRLLNLGNATGHPSFVMSNSF+N Sbjct 365 IDMAGLERSGAKRITVKPQVDQWIF-ESGKSIIVLSEGRLLNLGNATGHPSFVMSNSFSN 423 Query 428 QTIAQIELWTKNDEYDNEVYRLPKHLDEKVARIHVEALGGHLTKLTKEQAEYLGVDVEGP 487 Q IAQIELWTKNDEYDNEVYRLPKHLDEKVARIHVEALGG LTKLTKEQAEY+GVDVEGP Sbjct 424 QVIAQIELWTKNDEYDNEVYRLPKHLDEKVARIHVEALGGKLTKLTKEQAEYIGVDVEGP 483 Query 488 YKPDHYRY 495 YKP+HYRY Sbjct 484 YKPEHYRY 491 >gi|262203513|ref|YP_003274721.1| adenosylhomocysteinase [Gordonia bronchialis DSM 43247] gi|262086860|gb|ACY22828.1| adenosylhomocysteinase [Gordonia bronchialis DSM 43247] Length=489 Score = 878 bits (2269), Expect = 0.0, Method: Compositional matrix adjust. Identities = 420/490 (86%), Positives = 451/490 (93%), Gaps = 1/490 (0%) Query 6 VTKNSLTPDVRNGIDFKIADLSLADFGRKELRIAEHEMPGLMSLRREYAEVQPLKGARIS 65 +T + D RNGIDFK+ADLSLADFGRKE+ +AEHEMPGLMSLRREYA+V PLKGARIS Sbjct 1 MTSAAPQADTRNGIDFKVADLSLADFGRKEIELAEHEMPGLMSLRREYADVAPLKGARIS 60 Query 66 GSLHMTVQTAVLIETLTALGAEVRWASCNIFSTQDHAAAAVVVGPHGTPDEPKGVPVFAW 125 GSLHMTVQTAVLIETL ALGAEVRWASCNIFSTQDHAAAA+VVGPHGTPDEPKGVPVFAW Sbjct 61 GSLHMTVQTAVLIETLVALGAEVRWASCNIFSTQDHAAAAIVVGPHGTPDEPKGVPVFAW 120 Query 126 KGETLEEYWWAAEQMLTWPDPDKPANMILDDGGDATMLVLRGMQYEKAGVVPPAEEDDPA 185 KGETLEEYWWAAEQMLTWP+ DKPANMILDDGGDATMLVLRG ++EKAGVVPPAE+D A Sbjct 121 KGETLEEYWWAAEQMLTWPEADKPANMILDDGGDATMLVLRGAEFEKAGVVPPAEDDHSA 180 Query 186 EWKVFLNLLRTRFETDKDKWTKIAESVKGVTEETTTGVLRLYQFAAAGDLAFPAINVNDS 245 E+KVFL LLR FE DK KW+ IA+SV+GVTEETTTGVLRLYQFAAAGDLAFPAINVNDS Sbjct 181 EYKVFLELLRASFEKDKTKWSTIADSVQGVTEETTTGVLRLYQFAAAGDLAFPAINVNDS 240 Query 246 VTKSKFDNKYGTRHSLIDGINRGTDALIGGKKVLICGYGDVGKGCAEAMKGQGARVSVTE 305 VTKSKFDNKYGTRHSLIDGINRGTD LIGGKKVLICGYGDVGKGCAE++ GQGARV VTE Sbjct 241 VTKSKFDNKYGTRHSLIDGINRGTDVLIGGKKVLICGYGDVGKGCAESLAGQGARVQVTE 300 Query 306 IDPINALQAMMEGFDVVTVEEAIGDADIVVTATGNKDIIMLEHIKAMKDHAILGNIGHFD 365 IDPINALQA+M+GFDVVTVE+AI DADIV+T+TGN II L H++ MK AILGNIGHFD Sbjct 301 IDPINALQALMDGFDVVTVEQAIADADIVITSTGNLGIITLAHMRQMKHQAILGNIGHFD 360 Query 366 NEIDMAGLERSGATRVNVKPQVDLWTFGDTGRSIIVLSEGRLLNLGNATGHPSFVMSNSF 425 NEIDMAGLE SGA R+N+KPQVD W F D G+SIIVLSEGRLLNLGNATGHPSFVMSNSF Sbjct 361 NEIDMAGLEGSGAKRINIKPQVDQWIF-DDGKSIIVLSEGRLLNLGNATGHPSFVMSNSF 419 Query 426 ANQTIAQIELWTKNDEYDNEVYRLPKHLDEKVARIHVEALGGHLTKLTKEQAEYLGVDVE 485 +NQ IAQIELWTKNDEYDNEVYRLPKHLDEKVARIHVEALGG LT+LTKEQAEY+ VDVE Sbjct 420 SNQVIAQIELWTKNDEYDNEVYRLPKHLDEKVARIHVEALGGTLTRLTKEQAEYINVDVE 479 Query 486 GPYKPDHYRY 495 GPYKP+HYRY Sbjct 480 GPYKPEHYRY 489 >gi|41409460|ref|NP_962296.1| S-adenosyl-L-homocysteine hydrolase [Mycobacterium avium subsp. paratuberculosis K-10] gi|85543346|sp|Q73UK6.1|SAHH_MYCPA RecName: Full=Adenosylhomocysteinase; AltName: Full=S-adenosyl-L-homocysteine hydrolase; Short=AdoHcyase gi|41398291|gb|AAS05912.1| SahH [Mycobacterium avium subsp. paratuberculosis K-10] Length=496 Score = 877 bits (2266), Expect = 0.0, Method: Compositional matrix adjust. Identities = 418/493 (85%), Positives = 456/493 (93%), Gaps = 4/493 (0%) Query 7 TKNSLTPDVRNGIDFKIADLSLADFGRKELRIAEHEMPGLMSLRREYAEVQPLKGARISG 66 T+N+LTPDVRNGI+FK+ADLSLAD+GR+++ ++E EMPGLMSLRREY +VQPLKGARISG Sbjct 4 TENALTPDVRNGIEFKVADLSLADYGRRDIELSEQEMPGLMSLRREYHDVQPLKGARISG 63 Query 67 SLHMTVQTAVLIETLTALGAEVRWASCNIFSTQDHAAAAVVVGPHGTPDEPKGVPVFAWK 126 SLHMTVQTAVLIETL ALGAEVRWASCNIFSTQDHAAAAVVVGPHGTP+EP+GVPVFAWK Sbjct 64 SLHMTVQTAVLIETLVALGAEVRWASCNIFSTQDHAAAAVVVGPHGTPEEPRGVPVFAWK 123 Query 127 GETLEEYWWAAEQMLTWPD----PDKPANMILDDGGDATMLVLRGMQYEKAGVVPPAEED 182 GETLEEYWWAAEQ LTWP + PANMILDDGGDATMLVLRG QYEKAGVVPP +ED Sbjct 124 GETLEEYWWAAEQALTWPPLADGTEAPANMILDDGGDATMLVLRGAQYEKAGVVPPDDED 183 Query 183 DPAEWKVFLNLLRTRFETDKDKWTKIAESVKGVTEETTTGVLRLYQFAAAGDLAFPAINV 242 D AE +VFLNLLR RFETDK KWTKI+ES+KGVTEETTTGVLRLYQFAAAGDLAFPAINV Sbjct 184 DSAEHRVFLNLLRARFETDKTKWTKISESIKGVTEETTTGVLRLYQFAAAGDLAFPAINV 243 Query 243 NDSVTKSKFDNKYGTRHSLIDGINRGTDALIGGKKVLICGYGDVGKGCAEAMKGQGARVS 302 NDSVTKSKFDNKYG RHSLIDGINRGTD LIGGK VL+CGYGDVGKG E++ GQGARV+ Sbjct 244 NDSVTKSKFDNKYGCRHSLIDGINRGTDVLIGGKNVLVCGYGDVGKGSVESLAGQGARVT 303 Query 303 VTEIDPINALQAMMEGFDVVTVEEAIGDADIVVTATGNKDIIMLEHIKAMKDHAILGNIG 362 VTEIDPINALQA+MEG++V VE+ IG+ADIV+TATGNKDII LEH+KAMKD AILGNIG Sbjct 304 VTEIDPINALQALMEGYNVKRVEDVIGEADIVITATGNKDIITLEHMKAMKDKAILGNIG 363 Query 363 HFDNEIDMAGLERSGATRVNVKPQVDLWTFGDTGRSIIVLSEGRLLNLGNATGHPSFVMS 422 HFDNEI +A LE+SGA + N++PQVDLWTF DTG+SIIVLSEGRLLNLGNATGHPSFVMS Sbjct 364 HFDNEIQIARLEKSGAIKTNIRPQVDLWTFPDTGKSIIVLSEGRLLNLGNATGHPSFVMS 423 Query 423 NSFANQTIAQIELWTKNDEYDNEVYRLPKHLDEKVARIHVEALGGHLTKLTKEQAEYLGV 482 NSF+NQ IAQIELWTKNDEYDNEVYRLPKHLDEKVARIHVEALGG LTKLTKEQAEY+GV Sbjct 424 NSFSNQVIAQIELWTKNDEYDNEVYRLPKHLDEKVARIHVEALGGELTKLTKEQAEYIGV 483 Query 483 DVEGPYKPDHYRY 495 DV+GPYK DHYRY Sbjct 484 DVDGPYKADHYRY 496 >gi|118462675|ref|YP_883353.1| S-adenosyl-L-homocysteine hydrolase [Mycobacterium avium 104] gi|254776647|ref|ZP_05218163.1| S-adenosyl-L-homocysteine hydrolase [Mycobacterium avium subsp. avium ATCC 25291] gi|118163962|gb|ABK64859.1| adenosylhomocysteinase [Mycobacterium avium 104] gi|336459676|gb|EGO38611.1| adenosylhomocysteinase [Mycobacterium avium subsp. paratuberculosis S397] Length=496 Score = 877 bits (2265), Expect = 0.0, Method: Compositional matrix adjust. Identities = 418/493 (85%), Positives = 456/493 (93%), Gaps = 4/493 (0%) Query 7 TKNSLTPDVRNGIDFKIADLSLADFGRKELRIAEHEMPGLMSLRREYAEVQPLKGARISG 66 T+N+LTPDVRNGI+FK+ADLSLAD+GR+++ ++E EMPGLMSLRREY +VQPLKGARISG Sbjct 4 TENALTPDVRNGIEFKVADLSLADYGRRDIELSEQEMPGLMSLRREYHDVQPLKGARISG 63 Query 67 SLHMTVQTAVLIETLTALGAEVRWASCNIFSTQDHAAAAVVVGPHGTPDEPKGVPVFAWK 126 SLHMTVQTAVLIETL ALGAEVRWASCNIFSTQDHAAAAVVVGPHGTP+EP+GVPVFAWK Sbjct 64 SLHMTVQTAVLIETLVALGAEVRWASCNIFSTQDHAAAAVVVGPHGTPEEPRGVPVFAWK 123 Query 127 GETLEEYWWAAEQMLTWPD----PDKPANMILDDGGDATMLVLRGMQYEKAGVVPPAEED 182 GETLEEYWWAAEQ LTWP + PANMILDDGGDATMLVLRG QYEKAGVVPP +ED Sbjct 124 GETLEEYWWAAEQALTWPPLADGTEAPANMILDDGGDATMLVLRGAQYEKAGVVPPDDED 183 Query 183 DPAEWKVFLNLLRTRFETDKDKWTKIAESVKGVTEETTTGVLRLYQFAAAGDLAFPAINV 242 D AE +VFLNLLR RFETDK KWTKI+ES+KGVTEETTTGVLRLYQFAAAGDLAFPAINV Sbjct 184 DSAEHRVFLNLLRERFETDKTKWTKISESIKGVTEETTTGVLRLYQFAAAGDLAFPAINV 243 Query 243 NDSVTKSKFDNKYGTRHSLIDGINRGTDALIGGKKVLICGYGDVGKGCAEAMKGQGARVS 302 NDSVTKSKFDNKYG RHSLIDGINRGTD LIGGK VL+CGYGDVGKG E++ GQGARV+ Sbjct 244 NDSVTKSKFDNKYGCRHSLIDGINRGTDVLIGGKNVLVCGYGDVGKGSVESLAGQGARVT 303 Query 303 VTEIDPINALQAMMEGFDVVTVEEAIGDADIVVTATGNKDIIMLEHIKAMKDHAILGNIG 362 VTEIDPINALQA+MEG++V VE+ IG+ADIV+TATGNKDII LEH+KAMKD AILGNIG Sbjct 304 VTEIDPINALQALMEGYNVKRVEDVIGEADIVITATGNKDIITLEHMKAMKDKAILGNIG 363 Query 363 HFDNEIDMAGLERSGATRVNVKPQVDLWTFGDTGRSIIVLSEGRLLNLGNATGHPSFVMS 422 HFDNEI +A LE+SGA + N++PQVDLWTF DTG+SIIVLSEGRLLNLGNATGHPSFVMS Sbjct 364 HFDNEIQIARLEKSGAIKTNIRPQVDLWTFPDTGKSIIVLSEGRLLNLGNATGHPSFVMS 423 Query 423 NSFANQTIAQIELWTKNDEYDNEVYRLPKHLDEKVARIHVEALGGHLTKLTKEQAEYLGV 482 NSF+NQ IAQIELWTKNDEYDNEVYRLPKHLDEKVARIHVEALGG LTKLTKEQAEY+GV Sbjct 424 NSFSNQVIAQIELWTKNDEYDNEVYRLPKHLDEKVARIHVEALGGELTKLTKEQAEYIGV 483 Query 483 DVEGPYKPDHYRY 495 DV+GPYK DHYRY Sbjct 484 DVDGPYKADHYRY 496 >gi|296138919|ref|YP_003646162.1| adenosylhomocysteinase [Tsukamurella paurometabola DSM 20162] gi|296027053|gb|ADG77823.1| adenosylhomocysteinase [Tsukamurella paurometabola DSM 20162] Length=488 Score = 872 bits (2254), Expect = 0.0, Method: Compositional matrix adjust. Identities = 417/487 (86%), Positives = 454/487 (94%), Gaps = 3/487 (0%) Query 10 SLTPDVRNGIDFKIADLSLADFGRKELRIAEHEMPGLMSLRREYAEVQPLKGARISGSLH 69 +LT D NGIDFK+ADLSLA+ GRK+LR+AEHEMPGLM+LRREYA+VQPLKGARISGSLH Sbjct 4 ALTADTANGIDFKVADLSLAESGRKQLRLAEHEMPGLMALRREYADVQPLKGARISGSLH 63 Query 70 MTVQTAVLIETLTALGAEVRWASCNIFSTQDHAAAAVVVGPHGTPDEPKGVPVFAWKGET 129 MTVQTAVLIETL +LGAEVRWASCNIFSTQD AAAAVVVGP+GTP+ P+GVPVFAWKGET Sbjct 64 MTVQTAVLIETLASLGAEVRWASCNIFSTQDEAAAAVVVGPNGTPEAPQGVPVFAWKGET 123 Query 130 LEEYWWAAEQMLTWPDPDKPANMILDDGGDATMLVLRGMQYEKAGVVPPAEED-DPAEWK 188 LEEYWW AEQMLTWP+ +PANMILDDGGDATMLVLRG Q+E AGVVPP +ED D AE++ Sbjct 124 LEEYWWCAEQMLTWPN--EPANMILDDGGDATMLVLRGAQFEAAGVVPPTDEDADSAEYQ 181 Query 189 VFLNLLRTRFETDKDKWTKIAESVKGVTEETTTGVLRLYQFAAAGDLAFPAINVNDSVTK 248 VFL LLR D KW+ IAESVKGVTEETTTGVLRLYQFAAAG+LAFPAINVNDSVTK Sbjct 182 VFLALLRESLAKDATKWSTIAESVKGVTEETTTGVLRLYQFAAAGELAFPAINVNDSVTK 241 Query 249 SKFDNKYGTRHSLIDGINRGTDALIGGKKVLICGYGDVGKGCAEAMKGQGARVSVTEIDP 308 SKFDNKYGTRHSLIDGINRGTD LIGGKKVLI GYGDVGKGCAE++ GQGARV VTEIDP Sbjct 242 SKFDNKYGTRHSLIDGINRGTDVLIGGKKVLITGYGDVGKGCAESLAGQGARVQVTEIDP 301 Query 309 INALQAMMEGFDVVTVEEAIGDADIVVTATGNKDIIMLEHIKAMKDHAILGNIGHFDNEI 368 INALQA+M+GFDVVTVE+AIGDADIV+T+TGNKDII+LEH+KAMKDHAILGNIGHFDNEI Sbjct 302 INALQALMDGFDVVTVEQAIGDADIVITSTGNKDIILLEHMKAMKDHAILGNIGHFDNEI 361 Query 369 DMAGLERSGATRVNVKPQVDLWTFGDTGRSIIVLSEGRLLNLGNATGHPSFVMSNSFANQ 428 DMAGLE+SGA R+N+KPQVD WTFGDTG+SI+VLSEGRLLNLGNATGHPSFVMSNSF+NQ Sbjct 362 DMAGLEKSGAVRLNIKPQVDQWTFGDTGKSIVVLSEGRLLNLGNATGHPSFVMSNSFSNQ 421 Query 429 TIAQIELWTKNDEYDNEVYRLPKHLDEKVARIHVEALGGHLTKLTKEQAEYLGVDVEGPY 488 IAQIELWTK DEYDNEVYRLPKHLDEKVA+IHVEALGG LTKLTKEQAEY+GVDVEGPY Sbjct 422 VIAQIELWTKPDEYDNEVYRLPKHLDEKVAKIHVEALGGTLTKLTKEQAEYIGVDVEGPY 481 Query 489 KPDHYRY 495 KP+HYRY Sbjct 482 KPEHYRY 488 >gi|333991628|ref|YP_004524242.1| S-adenosyl-L-homocysteine hydrolase [Mycobacterium sp. JDM601] gi|333487596|gb|AEF36988.1| S-adenosyl-L-homocysteine hydrolase [Mycobacterium sp. JDM601] Length=485 Score = 864 bits (2232), Expect = 0.0, Method: Compositional matrix adjust. Identities = 415/486 (86%), Positives = 446/486 (92%), Gaps = 2/486 (0%) Query 10 SLTPDVRNGIDFKIADLSLADFGRKELRIAEHEMPGLMSLRREYAEVQPLKGARISGSLH 69 SLT D RNGID+K+ADLSLAD+GRKE+R+AEHEMPGLM+LR EY V PLKGARI+GSLH Sbjct 2 SLTADSRNGIDYKVADLSLADYGRKEIRLAEHEMPGLMALRNEYHGVNPLKGARITGSLH 61 Query 70 MTVQTAVLIETLTALGAEVRWASCNIFSTQDHAAAAVVVGPHGTPDEPKGVPVFAWKGET 129 MT+QTAVLIETL LGAEVRWASCNIFSTQDHAAAAVVVGPHGT +EPKG PVFAWKGE+ Sbjct 62 MTIQTAVLIETLVDLGAEVRWASCNIFSTQDHAAAAVVVGPHGTVEEPKGTPVFAWKGES 121 Query 130 LEEYWWAAEQMLTWPDPDKPANMILDDGGDATMLVLRGMQYEKAGVVPPAEEDDPAEWKV 189 LEEYWW AEQ LTW +PANMILDDGGDATM+VLRG QYEKAGVVPPAE+ D EWKV Sbjct 122 LEEYWWCAEQALTWEG--EPANMILDDGGDATMMVLRGAQYEKAGVVPPAEDGDSHEWKV 179 Query 190 FLNLLRTRFETDKDKWTKIAESVKGVTEETTTGVLRLYQFAAAGDLAFPAINVNDSVTKS 249 FL LR RFETDK KWTKIAESV+GVTEETTTGVLRLYQ AAAG+LAFPAINVNDSVTKS Sbjct 180 FLGTLRDRFETDKTKWTKIAESVQGVTEETTTGVLRLYQLAAAGELAFPAINVNDSVTKS 239 Query 250 KFDNKYGTRHSLIDGINRGTDALIGGKKVLICGYGDVGKGCAEAMKGQGARVSVTEIDPI 309 KFDNKYG RHSLIDGINRGTDALIGGKK L+CG+GDVGKG AE++KGQGARV+VTEIDPI Sbjct 240 KFDNKYGCRHSLIDGINRGTDALIGGKKALVCGFGDVGKGSAESLKGQGARVTVTEIDPI 299 Query 310 NALQAMMEGFDVVTVEEAIGDADIVVTATGNKDIIMLEHIKAMKDHAILGNIGHFDNEID 369 NALQA+MEG+DV TVE+AIG+ADIV+T TGNKDII LEH+KAMK+ AILGNIGHFDNEID Sbjct 300 NALQALMEGYDVATVEQAIGEADIVITTTGNKDIITLEHMKAMKNQAILGNIGHFDNEID 359 Query 370 MAGLERSGATRVNVKPQVDLWTFGDTGRSIIVLSEGRLLNLGNATGHPSFVMSNSFANQT 429 MA LE SGA R NVKPQVD+WTF DTGRSIIVLSEGRLLNLGNATGHPSFVMSNSF+NQ Sbjct 360 MAALETSGAVRDNVKPQVDVWTFPDTGRSIIVLSEGRLLNLGNATGHPSFVMSNSFSNQV 419 Query 430 IAQIELWTKNDEYDNEVYRLPKHLDEKVARIHVEALGGHLTKLTKEQAEYLGVDVEGPYK 489 IAQIELWTK DEYDNEVYRLPKHLDEKVARIHVEALGG LTKLTK+QAEY+GVDVEGPYK Sbjct 420 IAQIELWTKGDEYDNEVYRLPKHLDEKVARIHVEALGGTLTKLTKDQAEYIGVDVEGPYK 479 Query 490 PDHYRY 495 PDHYRY Sbjct 480 PDHYRY 485 >gi|226365792|ref|YP_002783575.1| S-adenosyl-L-homocysteine hydrolase [Rhodococcus opacus B4] gi|226244282|dbj|BAH54630.1| adenosylhomocysteinase [Rhodococcus opacus B4] Length=485 Score = 849 bits (2194), Expect = 0.0, Method: Compositional matrix adjust. Identities = 405/482 (85%), Positives = 446/482 (93%), Gaps = 3/482 (0%) Query 16 RNGIDFKIADLSLADFGRKELRIAEHEMPGLMSLRREYAEVQPLKGARISGSLHMTVQTA 75 RNGIDFK+ADLSLA+FGRKE+R+AEHEMPGLM+LRREYAEV PLKGARISGSLHMT+QTA Sbjct 5 RNGIDFKVADLSLAEFGRKEIRLAEHEMPGLMALRREYAEVLPLKGARISGSLHMTIQTA 64 Query 76 VLIETLTALGAEVRWASCNIFSTQDHAAAAVVVGPHGTPDEPKGVPVFAWKGETLEEYWW 135 VLIETLTALGAEVRWASCNIFSTQDHAAAA+VVGPHGTP+EP+G PVFAWKGETLEEYWW Sbjct 65 VLIETLTALGAEVRWASCNIFSTQDHAAAAIVVGPHGTPEEPQGTPVFAWKGETLEEYWW 124 Query 136 AAEQMLTWPDPDKPANMILDDGGDATMLVLRGMQYEKAGVVPPAEED-DPAEWKVFLNLL 194 AAEQMLTWPD DKPANMILDDGGDATMLVL+G Q+EKAGVVPP ++D D E+KVFL LL Sbjct 125 AAEQMLTWPDADKPANMILDDGGDATMLVLKGAQFEKAGVVPPTDDDQDSDEYKVFLALL 184 Query 195 RTRFETDKDKWTKIAESVKGVTEETTTGVLRLYQFAAAGDLAFPAINVNDSVTKSKFDNK 254 R E DK KWTK+AESV+GVTEETTTGVLRLYQ AAAG+L FPAINVNDSVTKSKFDNK Sbjct 185 RQSLEADKSKWTKVAESVQGVTEETTTGVLRLYQVAAAGELVFPAINVNDSVTKSKFDNK 244 Query 255 YGTRHSLIDGINRGTDALIGGKKVLICGYGDVGKGCAEAMKGQGARVSVTEIDPINALQA 314 YGTRHSL+DGINRGTD LIGGK L+CGYGDVGKGCAEA++GQGARV+VTE+DPINALQA Sbjct 245 YGTRHSLLDGINRGTDVLIGGKAALVCGYGDVGKGCAEALRGQGARVAVTEVDPINALQA 304 Query 315 MMEGFDVVTVEEAIGDADIVVTATGNKDIIMLEHIKAMKDHAILGNIGHFDNEIDMAGLE 374 +M+GF+V TVE+AIG ADI++T+TGNKDII +H+K MK AILGNIGHFDNEIDMAGLE Sbjct 305 LMDGFEVKTVEQAIGWADIIITSTGNKDIITFDHMKQMKHQAILGNIGHFDNEIDMAGLE 364 Query 375 RSG-ATRVNVKPQVDLWTFGDTGRSIIVLSEGRLLNLGNATGHPSFVMSNSFANQTIAQI 433 RSG TR+N+KPQVD + F D G SIIVLSEGRLLNLGNATGHPSFVMSNSF+NQ IAQI Sbjct 365 RSGEVTRINIKPQVDEFRFKD-GHSIIVLSEGRLLNLGNATGHPSFVMSNSFSNQVIAQI 423 Query 434 ELWTKNDEYDNEVYRLPKHLDEKVARIHVEALGGHLTKLTKEQAEYLGVDVEGPYKPDHY 493 ELWTK +EYDNEVYRLPKHLDEKVA+IHVEALGG LTKLTKEQAEY+GVDVEGP+KP+HY Sbjct 424 ELWTKPEEYDNEVYRLPKHLDEKVAKIHVEALGGTLTKLTKEQAEYIGVDVEGPFKPEHY 483 Query 494 RY 495 RY Sbjct 484 RY 485 >gi|111023285|ref|YP_706257.1| S-adenosyl-L-homocysteine hydrolase [Rhodococcus jostii RHA1] gi|110822815|gb|ABG98099.1| adenosylhomocysteinase [Rhodococcus jostii RHA1] Length=494 Score = 849 bits (2194), Expect = 0.0, Method: Compositional matrix adjust. Identities = 408/495 (83%), Positives = 451/495 (92%), Gaps = 5/495 (1%) Query 5 LVTKNSLTP--DVRNGIDFKIADLSLADFGRKELRIAEHEMPGLMSLRREYAEVQPLKGA 62 + T S TP + RNGIDFK+ADLSLA+FGRKE+R+AEHEMPGLM+LRREYAEV PLKGA Sbjct 1 MTTSVSTTPVAESRNGIDFKVADLSLAEFGRKEIRLAEHEMPGLMALRREYAEVLPLKGA 60 Query 63 RISGSLHMTVQTAVLIETLTALGAEVRWASCNIFSTQDHAAAAVVVGPHGTPDEPKGVPV 122 RISGSLHMT+QTAVLIETLTALGAEVRWASCNIFSTQDHAAAA+VVGPHGTP+EP+G PV Sbjct 61 RISGSLHMTIQTAVLIETLTALGAEVRWASCNIFSTQDHAAAAIVVGPHGTPEEPQGTPV 120 Query 123 FAWKGETLEEYWWAAEQMLTWPDPDKPANMILDDGGDATMLVLRGMQYEKAGVVPPAE-E 181 FAWKGETLEEYWWAAE+MLTWPD DKPANMILDDGGDATMLVL+G Q+EKAGVVPP + E Sbjct 121 FAWKGETLEEYWWAAEKMLTWPDADKPANMILDDGGDATMLVLKGAQFEKAGVVPPTDDE 180 Query 182 DDPAEWKVFLNLLRTRFETDKDKWTKIAESVKGVTEETTTGVLRLYQFAAAGDLAFPAIN 241 D E+KVFL LLR E DK KWTK+A+SV+GVTEETTTGVLRLYQ AAAG+L FPAIN Sbjct 181 QDSDEYKVFLALLRQSLEADKTKWTKVAQSVQGVTEETTTGVLRLYQVAAAGELTFPAIN 240 Query 242 VNDSVTKSKFDNKYGTRHSLIDGINRGTDALIGGKKVLICGYGDVGKGCAEAMKGQGARV 301 VNDSVTKSKFDNKYGTRHSL+DGINRGTD LIGGK L+CGYGDVGKGCAEA++GQGARV Sbjct 241 VNDSVTKSKFDNKYGTRHSLLDGINRGTDVLIGGKAALVCGYGDVGKGCAEALRGQGARV 300 Query 302 SVTEIDPINALQAMMEGFDVVTVEEAIGDADIVVTATGNKDIIMLEHIKAMKDHAILGNI 361 +VTE+DPINALQA+M+GF+V TVE+AIG ADIV+T+TGNKDII EH+K MK AILGNI Sbjct 301 AVTEVDPINALQALMDGFEVKTVEQAIGWADIVITSTGNKDIITFEHMKQMKHQAILGNI 360 Query 362 GHFDNEIDMAGLERSG-ATRVNVKPQVDLWTFGDTGRSIIVLSEGRLLNLGNATGHPSFV 420 GHFDNEIDMAGLERSG TR+N+KPQVD + F D G SIIVLSEGRLLNLGNATGHPSFV Sbjct 361 GHFDNEIDMAGLERSGEVTRINIKPQVDEFRFKD-GHSIIVLSEGRLLNLGNATGHPSFV 419 Query 421 MSNSFANQTIAQIELWTKNDEYDNEVYRLPKHLDEKVARIHVEALGGHLTKLTKEQAEYL 480 MSNSF+NQ IAQIELWTK +EYDNEVYRLPKHLDEKVA+IHVEALGG L+KLTKEQAEY+ Sbjct 420 MSNSFSNQVIAQIELWTKPEEYDNEVYRLPKHLDEKVAKIHVEALGGTLSKLTKEQAEYI 479 Query 481 GVDVEGPYKPDHYRY 495 GVDVEGP+KP+HYRY Sbjct 480 GVDVEGPFKPEHYRY 494 >gi|229489409|ref|ZP_04383272.1| adenosylhomocysteinase [Rhodococcus erythropolis SK121] gi|229323506|gb|EEN89264.1| adenosylhomocysteinase [Rhodococcus erythropolis SK121] Length=492 Score = 848 bits (2191), Expect = 0.0, Method: Compositional matrix adjust. Identities = 411/495 (84%), Positives = 453/495 (92%), Gaps = 7/495 (1%) Query 5 LVTKNSLTP--DVRNGIDFKIADLSLADFGRKELRIAEHEMPGLMSLRREYAEVQPLKGA 62 + T S TP + RNGIDFK+ADLSLA+FGRKE+R+AEHEMPGLM+LRREYAEV PLKGA Sbjct 1 MTTSVSTTPVAESRNGIDFKVADLSLAEFGRKEIRLAEHEMPGLMALRREYAEVLPLKGA 60 Query 63 RISGSLHMTVQTAVLIETLTALGAEVRWASCNIFSTQDHAAAAVVVGPHGTPDEPKGVPV 122 R+SGSLHMT+QTAVLIETLTALGAEVRWASCNIFSTQDHAAAA+VVGPHGTP+EPKGVPV Sbjct 61 RVSGSLHMTIQTAVLIETLTALGAEVRWASCNIFSTQDHAAAAIVVGPHGTPEEPKGVPV 120 Query 123 FAWKGETLEEYWWAAEQMLTWPDPDKPANMILDDGGDATMLVLRGMQYEKAGVVPPAEED 182 FAWKGETLEEYWWAAEQMLTWP +PANMILDDGGDATMLVL+G Q+EKAGVVPP ++D Sbjct 121 FAWKGETLEEYWWAAEQMLTWPG--EPANMILDDGGDATMLVLKGAQFEKAGVVPPTDDD 178 Query 183 -DPAEWKVFLNLLRTRFETDKDKWTKIAESVKGVTEETTTGVLRLYQFAAAGDLAFPAIN 241 D E+KVFL LLR E+DK KWT IAESV+GVTEETTTGVLRLYQ AAAG+L FPAIN Sbjct 179 QDSDEYKVFLALLRQSLESDKGKWTAIAESVQGVTEETTTGVLRLYQVAAAGELTFPAIN 238 Query 242 VNDSVTKSKFDNKYGTRHSLIDGINRGTDALIGGKKVLICGYGDVGKGCAEAMKGQGARV 301 VNDSVTKSKFDNKYGTRHSL+DGINRGTD LIGGK L+CGYGDVGKGCAEA++GQGARV Sbjct 239 VNDSVTKSKFDNKYGTRHSLLDGINRGTDVLIGGKAALVCGYGDVGKGCAEALRGQGARV 298 Query 302 SVTEIDPINALQAMMEGFDVVTVEEAIGDADIVVTATGNKDIIMLEHIKAMKDHAILGNI 361 +VTE+DPINALQA+M+GF+V TVE+AIG ADIV+T+TGNKDII EH+KAMK AILGNI Sbjct 299 AVTEVDPINALQALMDGFEVKTVEQAIGWADIVITSTGNKDIITFEHMKAMKHQAILGNI 358 Query 362 GHFDNEIDMAGLERSG-ATRVNVKPQVDLWTFGDTGRSIIVLSEGRLLNLGNATGHPSFV 420 GHFDNEIDMAGLE+SG TR+N+KPQVD +TF D G SIIVLSEGRLLNLGNATGHPSFV Sbjct 359 GHFDNEIDMAGLEKSGDVTRINIKPQVDEFTFAD-GHSIIVLSEGRLLNLGNATGHPSFV 417 Query 421 MSNSFANQTIAQIELWTKNDEYDNEVYRLPKHLDEKVARIHVEALGGHLTKLTKEQAEYL 480 MSNSF+NQ IAQIELWTK DEYDNEVYRLPKHLDEKVA+IHVEALGG LTKLTK+QAEY+ Sbjct 418 MSNSFSNQVIAQIELWTKPDEYDNEVYRLPKHLDEKVAKIHVEALGGTLTKLTKDQAEYI 477 Query 481 GVDVEGPYKPDHYRY 495 GVDVEGPYKP+HYRY Sbjct 478 GVDVEGPYKPEHYRY 492 >gi|312140678|ref|YP_004008014.1| adenosylhomocysteinase sahh [Rhodococcus equi 103S] gi|325675692|ref|ZP_08155376.1| adenosylhomocysteinase [Rhodococcus equi ATCC 33707] gi|311890017|emb|CBH49335.1| adenosylhomocysteinase SahH [Rhodococcus equi 103S] gi|325553663|gb|EGD23341.1| adenosylhomocysteinase [Rhodococcus equi ATCC 33707] Length=492 Score = 844 bits (2181), Expect = 0.0, Method: Compositional matrix adjust. Identities = 416/495 (85%), Positives = 447/495 (91%), Gaps = 7/495 (1%) Query 5 LVTKNSLTPDV--RNGIDFKIADLSLADFGRKELRIAEHEMPGLMSLRREYAEVQPLKGA 62 + T S P V R GIDFK+ADLSLA+FGRKE+R+AEHEMPGLM+LRREYA+V PLKGA Sbjct 1 MTTSVSSEPVVEHRGGIDFKVADLSLAEFGRKEIRLAEHEMPGLMALRREYADVLPLKGA 60 Query 63 RISGSLHMTVQTAVLIETLTALGAEVRWASCNIFSTQDHAAAAVVVGPHGTPDEPKGVPV 122 RISGSLHMT+QTAVLIETLTALGAEVRWASCNIFSTQDHAAAAVVVGPHGT DEPKGVPV Sbjct 61 RISGSLHMTIQTAVLIETLTALGAEVRWASCNIFSTQDHAAAAVVVGPHGTVDEPKGVPV 120 Query 123 FAWKGETLEEYWWAAEQMLTWPDPDKPANMILDDGGDATMLVLRGMQYEKAGVVPPAE-E 181 FAWKGETLEEYWWAAEQMLTWP ANMILDDGGDATMLVLRG QYEKAGVVPP + E Sbjct 121 FAWKGETLEEYWWAAEQMLTWPG--TTANMILDDGGDATMLVLRGAQYEKAGVVPPTDDE 178 Query 182 DDPAEWKVFLNLLRTRFETDKDKWTKIAESVKGVTEETTTGVLRLYQFAAAGDLAFPAIN 241 D E+KVFL LLR E D KWT IAESVKGVTEETTTGVLRLYQFAAAG+LAFPAIN Sbjct 179 HDSDEYKVFLALLRKSLEADGGKWTAIAESVKGVTEETTTGVLRLYQFAAAGELAFPAIN 238 Query 242 VNDSVTKSKFDNKYGTRHSLIDGINRGTDALIGGKKVLICGYGDVGKGCAEAMKGQGARV 301 VNDSVTKSKFDNKYGTRHSL+DGINRGTD LIGGK L+CGYGDVGKGCAEA++GQGARV Sbjct 239 VNDSVTKSKFDNKYGTRHSLLDGINRGTDVLIGGKAALVCGYGDVGKGCAEALRGQGARV 298 Query 302 SVTEIDPINALQAMMEGFDVVTVEEAIGDADIVVTATGNKDIIMLEHIKAMKDHAILGNI 361 +VTEIDPINALQAMM+G+DV TVEE IG+ADIV+TATGNKDII EH+K MK AILGNI Sbjct 299 TVTEIDPINALQAMMDGYDVKTVEEFIGEADIVITATGNKDIISFEHMKQMKHQAILGNI 358 Query 362 GHFDNEIDMAGLERSG-ATRVNVKPQVDLWTFGDTGRSIIVLSEGRLLNLGNATGHPSFV 420 GHFDNEIDMAGLER+G TR+N+KPQVD +TF D G SIIVLSEGRLLNLGNATGHPSFV Sbjct 359 GHFDNEIDMAGLERAGDVTRINIKPQVDEFTFAD-GHSIIVLSEGRLLNLGNATGHPSFV 417 Query 421 MSNSFANQTIAQIELWTKNDEYDNEVYRLPKHLDEKVARIHVEALGGHLTKLTKEQAEYL 480 MSNSFANQTIAQIELWTK +EYDNEVYRLPKHLDEKVA+IHVEALGG +TKLTK+QAEY+ Sbjct 418 MSNSFANQTIAQIELWTKPEEYDNEVYRLPKHLDEKVAKIHVEALGGSITKLTKDQAEYI 477 Query 481 GVDVEGPYKPDHYRY 495 GVDVEGPYKP+HYRY Sbjct 478 GVDVEGPYKPEHYRY 492 >gi|226305653|ref|YP_002765613.1| adenosylhomocysteinase [Rhodococcus erythropolis PR4] gi|226184770|dbj|BAH32874.1| adenosylhomocysteinase [Rhodococcus erythropolis PR4] Length=492 Score = 843 bits (2179), Expect = 0.0, Method: Compositional matrix adjust. Identities = 409/495 (83%), Positives = 450/495 (91%), Gaps = 7/495 (1%) Query 5 LVTKNSLTP--DVRNGIDFKIADLSLADFGRKELRIAEHEMPGLMSLRREYAEVQPLKGA 62 + T S TP + RNGIDFK+ADLSLA+FGRKE+R+AEHEMPGLM+LRREYAEV PLKGA Sbjct 1 MTTSVSTTPVAESRNGIDFKVADLSLAEFGRKEIRLAEHEMPGLMALRREYAEVLPLKGA 60 Query 63 RISGSLHMTVQTAVLIETLTALGAEVRWASCNIFSTQDHAAAAVVVGPHGTPDEPKGVPV 122 R+SGSLHMT+QTAVLIETLTALGAEVRWASCNIFSTQDHAAAA+VVGPHGTP+ PKGVPV Sbjct 61 RVSGSLHMTIQTAVLIETLTALGAEVRWASCNIFSTQDHAAAAIVVGPHGTPEAPKGVPV 120 Query 123 FAWKGETLEEYWWAAEQMLTWPDPDKPANMILDDGGDATMLVLRGMQYEKAGVVPPAEED 182 FAWKGETLEEYWWAAEQMLTWP +PANMILDDGGDATMLVL+G Q+EKAGVVPP ++D Sbjct 121 FAWKGETLEEYWWAAEQMLTWPG--EPANMILDDGGDATMLVLKGAQFEKAGVVPPTDDD 178 Query 183 -DPAEWKVFLNLLRTRFETDKDKWTKIAESVKGVTEETTTGVLRLYQFAAAGDLAFPAIN 241 D E+KVFL LLR DK KWT IAESV+GVTEETTTGVLRLYQ AAAG+L FPAIN Sbjct 179 QDSDEYKVFLALLRQSLAADKGKWTAIAESVQGVTEETTTGVLRLYQVAAAGELTFPAIN 238 Query 242 VNDSVTKSKFDNKYGTRHSLIDGINRGTDALIGGKKVLICGYGDVGKGCAEAMKGQGARV 301 VNDSVTKSKFDNKYGTRHSL+DGINRGTD LIGGK L+CGYGDVGKGCAEA++GQGARV Sbjct 239 VNDSVTKSKFDNKYGTRHSLLDGINRGTDVLIGGKAALVCGYGDVGKGCAEALRGQGARV 298 Query 302 SVTEIDPINALQAMMEGFDVVTVEEAIGDADIVVTATGNKDIIMLEHIKAMKDHAILGNI 361 +VTE+DPINALQA+M+GF+V TVE+AIG ADIV+T+TGNKDII EH+KAMK AILGNI Sbjct 299 AVTEVDPINALQALMDGFEVKTVEQAIGWADIVITSTGNKDIITFEHMKAMKHQAILGNI 358 Query 362 GHFDNEIDMAGLERSG-ATRVNVKPQVDLWTFGDTGRSIIVLSEGRLLNLGNATGHPSFV 420 GHFDNEIDMAGLE+SG TR+N+KPQVD +TF D G SIIVLSEGRLLNLGNATGHPSFV Sbjct 359 GHFDNEIDMAGLEKSGDVTRINIKPQVDEFTFAD-GHSIIVLSEGRLLNLGNATGHPSFV 417 Query 421 MSNSFANQTIAQIELWTKNDEYDNEVYRLPKHLDEKVARIHVEALGGHLTKLTKEQAEYL 480 MSNSF+NQ IAQIELWTK DEYDNEVYRLPKHLDEKVA+IHVEALGG LTKLTK+QAEY+ Sbjct 418 MSNSFSNQVIAQIELWTKPDEYDNEVYRLPKHLDEKVAKIHVEALGGTLTKLTKDQAEYI 477 Query 481 GVDVEGPYKPDHYRY 495 GVDVEGPYKP+HYRY Sbjct 478 GVDVEGPYKPEHYRY 492 >gi|326383261|ref|ZP_08204949.1| S-adenosyl-L-homocysteine hydrolase [Gordonia neofelifaecis NRRL B-59395] gi|326198011|gb|EGD55197.1| S-adenosyl-L-homocysteine hydrolase [Gordonia neofelifaecis NRRL B-59395] Length=490 Score = 835 bits (2156), Expect = 0.0, Method: Compositional matrix adjust. Identities = 401/488 (83%), Positives = 444/488 (91%), Gaps = 4/488 (0%) Query 9 NSLTPDVRNGIDFKIADLSLADFGRKELRIAEHEMPGLMSLRREYAEVQPLKGARISGSL 68 ++LT + RNG++FK+ADLS AD+GRKE+R+AEHEMPGLM LRREYA+V+PLKGARISGSL Sbjct 6 SALTTETRNGVEFKVADLSEADYGRKEIRLAEHEMPGLMELRREYADVKPLKGARISGSL 65 Query 69 HMTVQTAVLIETLTALGAEVRWASCNIFSTQDHAAAAVVVGPHGTPDEPKGVPVFAWKGE 128 HMTVQTAVLIETL LGA+VRWASCNIFSTQDHAAAAVVVGP+GT +EPKGVPVFAWKGE Sbjct 66 HMTVQTAVLIETLVDLGADVRWASCNIFSTQDHAAAAVVVGPYGTVEEPKGVPVFAWKGE 125 Query 129 TLEEYWWAAEQMLTWPDPDKPANMILDDGGDATMLVLRGMQYEKAGVVPPAEEDDPAEWK 188 TLEEYWWAAEQMLTWP +PANMILDDGGDATMLVLRG ++EKAGVVPPA++ PAE+K Sbjct 126 TLEEYWWAAEQMLTWPG--EPANMILDDGGDATMLVLRGAEFEKAGVVPPADDSHPAEYK 183 Query 189 VFLNLLRTRFETDKDKWTKIAESVKGVTEETTTGVLRLYQFAAAGDLAFPAINVNDSVTK 248 VFL LLR D KW+ IAESV+GVTEETTTGVLRLYQFAAAG+L FPAINVNDSVTK Sbjct 184 VFLELLRRSLAADSGKWSAIAESVQGVTEETTTGVLRLYQFAAAGELDFPAINVNDSVTK 243 Query 249 SKFDNKYGTRHSLIDGINRGTDALIGGKKVLICGYGDVGKGCAEAMKGQGARVSVTEIDP 308 SKFDNKYGTRHSL+DGINRGTD LIGGKKVL+CGYGDVGKGCAE++ GQGARV VTEIDP Sbjct 244 SKFDNKYGTRHSLVDGINRGTDVLIGGKKVLVCGYGDVGKGCAESLAGQGARVQVTEIDP 303 Query 309 INALQAMMEGFDVVTVEEAIGDADIVVTATGNKDIIMLEHIKAMKDHAILGNIGHFDNEI 368 INALQA+M+G+DVVTV+EAI +ADIV+TATGN II +H+K MK+ A+LGNIGHFDNEI Sbjct 304 INALQALMDGYDVVTVDEAIENADIVITATGNLGIISFDHMKKMKNQAVLGNIGHFDNEI 363 Query 369 DMAGLERS-GATRVNVKPQVDLWTFGDTGRSIIVLSEGRLLNLGNATGHPSFVMSNSFAN 427 DMAGLE + G TR+N+KPQVD W F D G SIIVLSEGRLLNLGNATGHPSFVMSNSFAN Sbjct 364 DMAGLESAEGMTRINIKPQVDQWVFPD-GHSIIVLSEGRLLNLGNATGHPSFVMSNSFAN 422 Query 428 QTIAQIELWTKNDEYDNEVYRLPKHLDEKVARIHVEALGGHLTKLTKEQAEYLGVDVEGP 487 Q IAQIELWTK DEYDNEVYRLPKHLDEKVARIHVEALGG LTKLTK+QAEY+GVDVEGP Sbjct 423 QVIAQIELWTKADEYDNEVYRLPKHLDEKVARIHVEALGGSLTKLTKDQAEYIGVDVEGP 482 Query 488 YKPDHYRY 495 YKP+HYRY Sbjct 483 YKPEHYRY 490 >gi|333921451|ref|YP_004495032.1| adenosylhomocysteinase [Amycolicicoccus subflavus DQS3-9A1] gi|333483672|gb|AEF42232.1| Adenosylhomocysteinase [Amycolicicoccus subflavus DQS3-9A1] Length=490 Score = 806 bits (2083), Expect = 0.0, Method: Compositional matrix adjust. Identities = 385/482 (80%), Positives = 430/482 (90%), Gaps = 3/482 (0%) Query 16 RNGIDFKIADLSLADFGRKELRIAEHEMPGLMSLRREYAEVQPLKGARISGSLHMTVQTA 75 RNG+D+K+ADLSLA+FGRKE+R+AEHEMPGLM+LRREYAEVQPLKGARI+GSLHMTVQTA Sbjct 10 RNGLDYKVADLSLAEFGRKEIRLAEHEMPGLMTLRREYAEVQPLKGARITGSLHMTVQTA 69 Query 76 VLIETLTALGAEVRWASCNIFSTQDHAAAAVVVGPHGTPDEPKGVPVFAWKGETLEEYWW 135 VLIETLTALGA VRWASCNIFSTQDHAAAA+VVGP+GTP++P+GVPV+AWKGETLEEYWW Sbjct 70 VLIETLTALGASVRWASCNIFSTQDHAAAAIVVGPYGTPEDPQGVPVYAWKGETLEEYWW 129 Query 136 AAEQMLTWPDPDKPANMILDDGGDATMLVLRGMQYEKAGVVPPAEEDD-PAEWKVFLNLL 194 E+ LTWPD PANMILDDGGDATMLVLRG Q+E AG VPP + D AE++VFL LL Sbjct 130 CTEKALTWPDEAGPANMILDDGGDATMLVLRGAQFEAAGTVPPIDPDQHSAEYQVFLGLL 189 Query 195 RTRFETDKDKWTKIAESVKGVTEETTTGVLRLYQFAAAGDLAFPAINVNDSVTKSKFDNK 254 + E D KWT+IA+SV+GVTEETTTGV RLYQFAAAG+L FPAINVNDSVTKSKFDNK Sbjct 190 QRSLEADGKKWTRIADSVQGVTEETTTGVHRLYQFAAAGELVFPAINVNDSVTKSKFDNK 249 Query 255 YGTRHSLIDGINRGTDALIGGKKVLICGYGDVGKGCAEAMKGQGARVSVTEIDPINALQA 314 YGTRHSL+DGINRGTD LIGGK ++CGYGDVGKG AEA++GQGARV+VTE+DPINALQA Sbjct 250 YGTRHSLLDGINRGTDVLIGGKYAVVCGYGDVGKGSAEALRGQGARVTVTEVDPINALQA 309 Query 315 MMEGFDVVTVEEAIGDADIVVTATGNKDIIMLEHIKAMKDHAILGNIGHFDNEIDMAGLE 374 MM+GF V TV+E I ADIV+TATGN ++I EH++ MK AILGNIGHFDNEIDMAGLE Sbjct 310 MMDGFHVATVDEVISAADIVITATGNMNVITFEHMQRMKHQAILGNIGHFDNEIDMAGLE 369 Query 375 RSGATRVN-VKPQVDLWTFGDTGRSIIVLSEGRLLNLGNATGHPSFVMSNSFANQTIAQI 433 ++ R + +KPQVD W F D G SIIVLSEGRLLNLGNATGHPSFVMSNSF+NQ IAQ+ Sbjct 370 KAPNVRRDTIKPQVDEWMF-DDGHSIIVLSEGRLLNLGNATGHPSFVMSNSFSNQVIAQL 428 Query 434 ELWTKNDEYDNEVYRLPKHLDEKVARIHVEALGGHLTKLTKEQAEYLGVDVEGPYKPDHY 493 ELWTK DEYDNEVYRLPKHLDEKVARIHVEALGG LTKLTKEQAEY+GVDVEGPYKPDHY Sbjct 429 ELWTKKDEYDNEVYRLPKHLDEKVARIHVEALGGSLTKLTKEQAEYIGVDVEGPYKPDHY 488 Query 494 RY 495 RY Sbjct 489 RY 490 >gi|296394615|ref|YP_003659499.1| adenosylhomocysteinase [Segniliparus rotundus DSM 44985] gi|296181762|gb|ADG98668.1| adenosylhomocysteinase [Segniliparus rotundus DSM 44985] Length=490 Score = 801 bits (2069), Expect = 0.0, Method: Compositional matrix adjust. Identities = 386/488 (80%), Positives = 434/488 (89%), Gaps = 4/488 (0%) Query 9 NSLTPDVRNGIDFKIADLSLADFGRKELRIAEHEMPGLMSLRREYAEVQPLKGARISGSL 68 N L D +++K+ADLSLA++GRKE+R+AEHEMPGL++LRREY V PLKGARI+GSL Sbjct 6 NGLVADFAGDLEYKVADLSLAEYGRKEIRLAEHEMPGLIALRREYDGVFPLKGARITGSL 65 Query 69 HMTVQTAVLIETLTALGAEVRWASCNIFSTQDHAAAAVVVGPHGTPDEPKGVPVFAWKGE 128 HMT+QTAVLIETL ALGAEVRWASCNIFSTQDHAAAAVVVGPHGT D+PKGVPVFAWKGE Sbjct 66 HMTIQTAVLIETLVALGAEVRWASCNIFSTQDHAAAAVVVGPHGTVDQPKGVPVFAWKGE 125 Query 129 TLEEYWWAAEQMLTWPDPDKPANMILDDGGDATMLVLRGMQYEKAGVVPPAEEDDPAEWK 188 TL+EYWWA ++ L+W D +PANMILDDGGDATMLVLRG QYEKAGVVPPAEEDD EW+ Sbjct 126 TLDEYWWALDRALSWKD--EPANMILDDGGDATMLVLRGAQYEKAGVVPPAEEDDSEEWQ 183 Query 189 VFLNLLRTRFETDKDKWTKIAESVKGVTEETTTGVLRLYQFAAAGDLAFPAINVNDSVTK 248 FL L+R E D KWT+IA SV+GVTEETTTGVLRLYQF+AA +L FPAINVNDSVTK Sbjct 184 AFLKLVRALHEADSGKWTRIAGSVRGVTEETTTGVLRLYQFSAAKELPFPAINVNDSVTK 243 Query 249 SKFDNKYGTRHSLIDGINRGTDALIGGKKVLICGYGDVGKGCAEAMKGQGARVSVTEIDP 308 SKFDNKYG RHSL+DGINRGTD LIGGKKVL+CGYGDVGKG +++ GQGARV+VTEIDP Sbjct 244 SKFDNKYGCRHSLVDGINRGTDVLIGGKKVLVCGYGDVGKGSVQSLAGQGARVTVTEIDP 303 Query 309 INALQAMMEGFDVVTVEEAIGDADIVVTATGNKDIIMLEHIKAMKDHAILGNIGHFDNEI 368 INALQA+M+G+DV TVE+AIG+ADIV+T TGN +II LEH++ MK AILGNIGHFDNEI Sbjct 304 INALQALMDGYDVRTVEQAIGEADIVITTTGNVNIITLEHMRQMKHQAILGNIGHFDNEI 363 Query 369 DMAGLERS-GATRVNVKPQVDLWTFGDTGRSIIVLSEGRLLNLGNATGHPSFVMSNSFAN 427 DM GL + TRVN+KPQVD +TFG+ G+SIIVLSEGRLLNLGNATGHPSFVMSNSF+N Sbjct 364 DMHGLTHAPDVTRVNIKPQVDEFTFGN-GKSIIVLSEGRLLNLGNATGHPSFVMSNSFSN 422 Query 428 QTIAQIELWTKNDEYDNEVYRLPKHLDEKVARIHVEALGGHLTKLTKEQAEYLGVDVEGP 487 Q IAQIELWTK DEYDNEVYRLPKHLDEKVA+IHVEALGG LTKLTKEQAEY+GVDVEGP Sbjct 423 QVIAQIELWTKPDEYDNEVYRLPKHLDEKVAKIHVEALGGTLTKLTKEQAEYIGVDVEGP 482 Query 488 YKPDHYRY 495 YKP+HYRY Sbjct 483 YKPEHYRY 490 >gi|256380309|ref|YP_003103969.1| S-adenosyl-L-homocysteine hydrolase [Actinosynnema mirum DSM 43827] gi|255924612|gb|ACU40123.1| adenosylhomocysteinase [Actinosynnema mirum DSM 43827] Length=490 Score = 778 bits (2008), Expect = 0.0, Method: Compositional matrix adjust. Identities = 371/481 (78%), Positives = 418/481 (87%), Gaps = 3/481 (0%) Query 16 RNGIDFKIADLSLADFGRKELRIAEHEMPGLMSLRREYAEVQPLKGARISGSLHMTVQTA 75 RNGIDF +ADLSLADFGRKE+R+AEHEMPGLM+LRREYAEV PLKGAR+SGSLHMTVQTA Sbjct 12 RNGIDFAVADLSLADFGRKEIRLAEHEMPGLMALRREYAEVYPLKGARVSGSLHMTVQTA 71 Query 76 VLIETLTALGAEVRWASCNIFSTQDHAAAAVVVGPHGTPDEPKGVPVFAWKGETLEEYWW 135 VLIETL ALGAEVRWASCNIFSTQDHAAAAVVVGPHGTP+EP+GVPVFAWKGE+L EYWW Sbjct 72 VLIETLVALGAEVRWASCNIFSTQDHAAAAVVVGPHGTPEEPRGVPVFAWKGESLAEYWW 131 Query 136 AAEQMLTWPDPDKPANMILDDGGDATMLVLRGMQYEKAGVVPPAEEDDPAEWKVFLNLLR 195 AE MLTWPD P NMILDDGGDAT+LV +G QYEKAGVVP A EDD EW + L LR Sbjct 132 TAESMLTWPDGQGP-NMILDDGGDATLLVHKGAQYEKAGVVPAASEDDSEEWALVLETLR 190 Query 196 TRFETDKDKWTKIAESVKGVTEETTTGVLRLYQFAAAGDLAFPAINVNDSVTKSKFDNKY 255 +D KWT+IAE ++GVTEETTTGV+RLYQ AAAG+L FPAINVND+VTKSKFDN+Y Sbjct 191 NSLASDAGKWTRIAEGIRGVTEETTTGVMRLYQLAAAGELLFPAINVNDAVTKSKFDNRY 250 Query 256 GTRHSLIDGINRGTDALIGGKKVLICGYGDVGKGCAEAMKGQGARVSVTEIDPINALQAM 315 G RHSLIDGINRGTD L+GGK +ICGYGDVGKG AE+++GQGAR+ VTEIDPI ALQA+ Sbjct 251 GIRHSLIDGINRGTDVLMGGKVAVICGYGDVGKGAAESLRGQGARIVVTEIDPICALQAV 310 Query 316 MEGFDVVTVEEAIGDADIVVTATGNKDIIMLEHIKAMKDHAILGNIGHFDNEIDMAGLER 375 M+G+DV T+E + ADIV+T TGNKD++ +EH+ AMK AI+GNIGHFDNEIDMAGL R Sbjct 311 MDGYDVQTLESVLPRADIVITTTGNKDVVRIEHMAAMKHQAIVGNIGHFDNEIDMAGLAR 370 Query 376 -SGATRVNVKPQVDLWTFGDTGRSIIVLSEGRLLNLGNATGHPSFVMSNSFANQTIAQIE 434 G R+N+KPQVD W F D G SI+VLSEGRLLNLGNATGHPSFVMSNSF+NQ IAQIE Sbjct 371 FPGVRRINIKPQVDEWVFPD-GHSILVLSEGRLLNLGNATGHPSFVMSNSFSNQVIAQIE 429 Query 435 LWTKNDEYDNEVYRLPKHLDEKVARIHVEALGGHLTKLTKEQAEYLGVDVEGPYKPDHYR 494 L+ K+ EYD EVYRLPK LDEKVARIH+EALGG LTKL+K+QAEY+ VDVEGPYKP+HYR Sbjct 430 LFGKHTEYDREVYRLPKKLDEKVARIHLEALGGELTKLSKDQAEYIDVDVEGPYKPEHYR 489 Query 495 Y 495 Y Sbjct 490 Y 490 >gi|256377202|ref|YP_003100862.1| S-adenosyl-L-homocysteine hydrolase [Actinosynnema mirum DSM 43827] gi|255921505|gb|ACU37016.1| adenosylhomocysteinase [Actinosynnema mirum DSM 43827] Length=491 Score = 777 bits (2006), Expect = 0.0, Method: Compositional matrix adjust. Identities = 371/481 (78%), Positives = 418/481 (87%), Gaps = 3/481 (0%) Query 16 RNGIDFKIADLSLADFGRKELRIAEHEMPGLMSLRREYAEVQPLKGARISGSLHMTVQTA 75 RNGIDF +ADLSLADFGRKE+R+AEHEMPGLM+LRREYAEV PLKGAR+SGSLHMTVQTA Sbjct 13 RNGIDFAVADLSLADFGRKEIRLAEHEMPGLMALRREYAEVYPLKGARVSGSLHMTVQTA 72 Query 76 VLIETLTALGAEVRWASCNIFSTQDHAAAAVVVGPHGTPDEPKGVPVFAWKGETLEEYWW 135 VLIETL ALGAEVRWASCNIFSTQDHAAAAVVVGPHGTP+EPKGVPVFAWKGE+L EYWW Sbjct 73 VLIETLVALGAEVRWASCNIFSTQDHAAAAVVVGPHGTPEEPKGVPVFAWKGESLAEYWW 132 Query 136 AAEQMLTWPDPDKPANMILDDGGDATMLVLRGMQYEKAGVVPPAEEDDPAEWKVFLNLLR 195 AE MLTWPD P NMILDDGGDAT+LV +G QYEKAGVVP A EDD EW + L LR Sbjct 133 TAESMLTWPDGQGP-NMILDDGGDATLLVHKGAQYEKAGVVPAASEDDSEEWALVLETLR 191 Query 196 TRFETDKDKWTKIAESVKGVTEETTTGVLRLYQFAAAGDLAFPAINVNDSVTKSKFDNKY 255 +D KWT+IAE ++GVTEETTTGV+RLYQ AAAG+L FPAINVND+VTKSKFDN+Y Sbjct 192 NSLASDAGKWTRIAEGIRGVTEETTTGVMRLYQLAAAGELLFPAINVNDAVTKSKFDNRY 251 Query 256 GTRHSLIDGINRGTDALIGGKKVLICGYGDVGKGCAEAMKGQGARVSVTEIDPINALQAM 315 G RHSLIDGINRGTD L+GGK +ICGYGDVGKG AE+++GQGAR+ VTEIDPI ALQA+ Sbjct 252 GIRHSLIDGINRGTDVLMGGKVAVICGYGDVGKGAAESLRGQGARIVVTEIDPICALQAI 311 Query 316 MEGFDVVTVEEAIGDADIVVTATGNKDIIMLEHIKAMKDHAILGNIGHFDNEIDMAGLER 375 M+G+DV T+E + ADIV+T TGNKD++ +EH+ AMK AI+GNIGHFDNEIDMAGL R Sbjct 312 MDGYDVQTLESVLPRADIVITTTGNKDVVRIEHMAAMKHQAIVGNIGHFDNEIDMAGLAR 371 Query 376 -SGATRVNVKPQVDLWTFGDTGRSIIVLSEGRLLNLGNATGHPSFVMSNSFANQTIAQIE 434 G R+N+KPQVD W F D G SI+VLSEGRLLNLGNATGHPSFVMSNSF+NQ IAQIE Sbjct 372 FPGVRRINIKPQVDEWVFPD-GHSILVLSEGRLLNLGNATGHPSFVMSNSFSNQVIAQIE 430 Query 435 LWTKNDEYDNEVYRLPKHLDEKVARIHVEALGGHLTKLTKEQAEYLGVDVEGPYKPDHYR 494 L+ K+ EYD EVYRLPK LDEKVARIH+EALGG LTKL+K+QAEY+ VDV+GPYKP+HYR Sbjct 431 LFGKHTEYDREVYRLPKKLDEKVARIHLEALGGELTKLSKDQAEYIDVDVDGPYKPEHYR 490 Query 495 Y 495 Y Sbjct 491 Y 491 >gi|317508026|ref|ZP_07965716.1| adenosylhomocysteinase [Segniliparus rugosus ATCC BAA-974] gi|316253688|gb|EFV13068.1| adenosylhomocysteinase [Segniliparus rugosus ATCC BAA-974] Length=490 Score = 776 bits (2004), Expect = 0.0, Method: Compositional matrix adjust. Identities = 379/488 (78%), Positives = 422/488 (87%), Gaps = 4/488 (0%) Query 9 NSLTPDVRNGIDFKIADLSLADFGRKELRIAEHEMPGLMSLRREYAEVQPLKGARISGSL 68 N L D +D+K+ADL+LADFGRKE+++AEHEMPGLM+LRREY V PLKGARI+GSL Sbjct 6 NGLVADFAGDLDYKVADLTLADFGRKEIQLAEHEMPGLMALRREYDGVFPLKGARITGSL 65 Query 69 HMTVQTAVLIETLTALGAEVRWASCNIFSTQDHAAAAVVVGPHGTPDEPKGVPVFAWKGE 128 HMT+QTAVLIETL ALGAEVRWASCNIFSTQDHAAAAVVVGPHGT DEPKGVPVFAWKGE Sbjct 66 HMTIQTAVLIETLVALGAEVRWASCNIFSTQDHAAAAVVVGPHGTVDEPKGVPVFAWKGE 125 Query 129 TLEEYWWAAEQMLTWPDPDKPANMILDDGGDATMLVLRGMQYEKAGVVPPAEEDDPAEWK 188 TL+EYWWA ++ L+W +PANMILDDGGDAT +VLRG Q+EKAGVVPP EE D E+K Sbjct 126 TLDEYWWALDRALSWSG--EPANMILDDGGDATTVVLRGAQFEKAGVVPPEEEGDSDEYK 183 Query 189 VFLNLLRTRFETDKDKWTKIAESVKGVTEETTTGVLRLYQFAAAGDLAFPAINVNDSVTK 248 L L R TD KWT IA SV+GVTEETTTGV RLYQF+AA +L FPAINVNDSVTK Sbjct 184 ELLKLFRGWLATDPQKWTNIAASVRGVTEETTTGVHRLYQFSAAKELPFPAINVNDSVTK 243 Query 249 SKFDNKYGTRHSLIDGINRGTDALIGGKKVLICGYGDVGKGCAEAMKGQGARVSVTEIDP 308 SKFDNKYG RHSLIDGINRG D LIGGKK L+CGYGDVGKG +++ GQGARV+VTEIDP Sbjct 244 SKFDNKYGCRHSLIDGINRGVDVLIGGKKALVCGYGDVGKGSVQSLAGQGARVTVTEIDP 303 Query 309 INALQAMMEGFDVVTVEEAIGDADIVVTATGNKDIIMLEHIKAMKDHAILGNIGHFDNEI 368 INALQA+M+GFDV TVEEAIG+ADIV+T TGN II LEH++ MKD AILGNIGHFDNEI Sbjct 304 INALQALMDGFDVKTVEEAIGEADIVITTTGNVGIITLEHMRMMKDQAILGNIGHFDNEI 363 Query 369 DMAGLERS-GATRVNVKPQVDLWTFGDTGRSIIVLSEGRLLNLGNATGHPSFVMSNSFAN 427 DM GL + TR+N+KPQVD + FG+ G+SIIVLSEGRLLNLGNATGHPSFVMSNSF+N Sbjct 364 DMHGLTHAPDVTRLNIKPQVDQFFFGN-GKSIIVLSEGRLLNLGNATGHPSFVMSNSFSN 422 Query 428 QTIAQIELWTKNDEYDNEVYRLPKHLDEKVARIHVEALGGHLTKLTKEQAEYLGVDVEGP 487 Q IAQIELWTK +EY NEVYRLPKHLDEKVA+IHVEALGG LTKLTKEQAEY+GVDVEGP Sbjct 423 QVIAQIELWTKPNEYANEVYRLPKHLDEKVAKIHVEALGGTLTKLTKEQAEYIGVDVEGP 482 Query 488 YKPDHYRY 495 YKP+HYRY Sbjct 483 YKPEHYRY 490 >gi|302530033|ref|ZP_07282375.1| adenosylhomocysteinase [Streptomyces sp. AA4] gi|302438928|gb|EFL10744.1| adenosylhomocysteinase [Streptomyces sp. AA4] Length=490 Score = 773 bits (1996), Expect = 0.0, Method: Compositional matrix adjust. Identities = 371/483 (77%), Positives = 421/483 (88%), Gaps = 4/483 (0%) Query 14 DVRNGIDFKIADLSLADFGRKELRIAEHEMPGLMSLRREYAEVQPLKGARISGSLHMTVQ 73 D R GI+F +ADL A+FGRKE+R+AEHEMPGLM+LRREYAEV PL+GARI+GSLHMTVQ Sbjct 11 DTRGGIEFAVADLDAAEFGRKEIRLAEHEMPGLMALRREYAEVYPLRGARIAGSLHMTVQ 70 Query 74 TAVLIETLTALGAEVRWASCNIFSTQDHAAAAVVVGPHGTPDEPKGVPVFAWKGETLEEY 133 TAVLIETL ALGAEVRWASCNIFSTQDHAAAAVVVGPHGTP+EPKGVPVFAWKGETLEEY Sbjct 71 TAVLIETLVALGAEVRWASCNIFSTQDHAAAAVVVGPHGTPEEPKGVPVFAWKGETLEEY 130 Query 134 WWAAEQMLTWPDPDKPANMILDDGGDATMLVLRGMQYEKAGVVPPAEEDDPAEWKVFLNL 193 WW E+MLTW + + P NMILDDGGDATMLV +G +YEKAGVVPPA+++DP EWKVFL L Sbjct 131 WWCTERMLTW-EGEGP-NMILDDGGDATMLVHKGTEYEKAGVVPPADDEDPEEWKVFLEL 188 Query 194 LRTRFETDKDKWTKIAESVKGVTEETTTGVLRLYQFAAAGDLAFPAINVNDSVTKSKFDN 253 LR DK KWT I +SVKGVTEETTTGVLRLYQ AAAG+L FPAINVNDSVTKSKFDN Sbjct 189 LRASVAADKGKWTAIGQSVKGVTEETTTGVLRLYQLAAAGELLFPAINVNDSVTKSKFDN 248 Query 254 KYGTRHSLIDGINRGTDALIGGKKVLICGYGDVGKGCAEAMKGQGARVSVTEIDPINALQ 313 +YG RHSLIDGINRGTD LIGGK ++CGYGDVGKG AE+++GQGARV +TEIDPI ALQ Sbjct 249 RYGIRHSLIDGINRGTDVLIGGKVAVVCGYGDVGKGAAESLRGQGARVIITEIDPICALQ 308 Query 314 AMMEGFDVVTVEEAIGDADIVVTATGNKDIIMLEHIKAMKDHAILGNIGHFDNEIDMAGL 373 AMM+G++V +E + + DI VT TGNK+++M+EH+ MK AI+GNIGHFDNE+DMAGL Sbjct 309 AMMDGYEVKRLESVLDEGDIYVTTTGNKNVVMVEHMARMKHQAIVGNIGHFDNELDMAGL 368 Query 374 ER-SGATRVNVKPQVDLWTFGDTGRSIIVLSEGRLLNLGNATGHPSFVMSNSFANQTIAQ 432 R G RVN+KPQVD W F D G+SI+VLSEGRLLNLGNATGHPSFVMSNSFANQ IAQ Sbjct 369 ARYPGVRRVNIKPQVDEWVFPD-GKSILVLSEGRLLNLGNATGHPSFVMSNSFANQVIAQ 427 Query 433 IELWTKNDEYDNEVYRLPKHLDEKVARIHVEALGGHLTKLTKEQAEYLGVDVEGPYKPDH 492 +EL+TK +EYD EVYRLPK LDEKVARIH+EALGG LTKL+KEQAEY+ VDVEGP+K +H Sbjct 428 VELFTKTEEYDKEVYRLPKKLDEKVARIHLEALGGELTKLSKEQAEYIDVDVEGPFKSEH 487 Query 493 YRY 495 YRY Sbjct 488 YRY 490 >gi|134102884|ref|YP_001108545.1| S-adenosyl-L-homocysteine hydrolase [Saccharopolyspora erythraea NRRL 2338] gi|291009671|ref|ZP_06567644.1| S-adenosyl-L-homocysteine hydrolase [Saccharopolyspora erythraea NRRL 2338] gi|133915507|emb|CAM05620.1| S-adenosyl-L-homocysteine hydrolase [Saccharopolyspora erythraea NRRL 2338] Length=487 Score = 760 bits (1963), Expect = 0.0, Method: Compositional matrix adjust. Identities = 363/482 (76%), Positives = 414/482 (86%), Gaps = 3/482 (0%) Query 15 VRNGIDFKIADLSLADFGRKELRIAEHEMPGLMSLRREYAEVQPLKGARISGSLHMTVQT 74 VRNGI+F IAD A GR ++R+AEHEMPGLM+LRREYAEV PL+GAR+SGSLHMTVQT Sbjct 8 VRNGIEFAIADPGAATAGRHQIRLAEHEMPGLMALRREYAEVFPLRGARVSGSLHMTVQT 67 Query 75 AVLIETLTALGAEVRWASCNIFSTQDHAAAAVVVGPHGTPDEPKGVPVFAWKGETLEEYW 134 AVLIETL ALGAEVRWASCNIFST D AAAAVVVGPHGTPDEP+GVPVFAWKGETLEEYW Sbjct 68 AVLIETLVALGAEVRWASCNIFSTDDSAAAAVVVGPHGTPDEPRGVPVFAWKGETLEEYW 127 Query 135 WAAEQMLTWPDPDKPANMILDDGGDATMLVLRGMQYEKAGVVPPAEEDDPAEWKVFLNLL 194 W E+MLTWP P NMILDDGGDAT+LV +G+QYE+AGVVP +DDP E+KV L L Sbjct 128 WCTERMLTWPGEAGP-NMILDDGGDATLLVHKGVQYERAGVVPNPADDDPDEFKVILQTL 186 Query 195 RTRFETDKDKWTKIAESVKGVTEETTTGVLRLYQFAAAGDLAFPAINVNDSVTKSKFDNK 254 R D KWT+ AE ++GVTEETTTGV RLYQ AA G+L FPAINVNDSVTKSKFDNK Sbjct 187 RASLAADTTKWTRAAERIRGVTEETTTGVNRLYQLAAQGELLFPAINVNDSVTKSKFDNK 246 Query 255 YGTRHSLIDGINRGTDALIGGKKVLICGYGDVGKGCAEAMKGQGARVSVTEIDPINALQA 314 YG RHSLIDGINR TD L+GGK ++CGYGDVGKG AE+++GQ ARV +TE+DPINALQA Sbjct 247 YGIRHSLIDGINRATDVLVGGKVAVVCGYGDVGKGSAESLRGQRARVIITEVDPINALQA 306 Query 315 MMEGFDVVTVEEAIGDADIVVTATGNKDIIMLEHIKAMKDHAILGNIGHFDNEIDMAGLE 374 +++G++V ++ IG ADIV+TATGNKDI+ ++H++ MK A+LGN+GHFDNEIDMAGLE Sbjct 307 LLDGYEVARLDSVIGQADIVITATGNKDIVTVDHMRRMKHQAVLGNVGHFDNEIDMAGLE 366 Query 375 RS-GATRVNVKPQVDLWTFGDTGRSIIVLSEGRLLNLGNATGHPSFVMSNSFANQTIAQI 433 R+ G R+N+KPQVD W F D GRSIIVLSEGRLLNLGNATGHPSFVMSNSF+NQTIAQI Sbjct 367 RADGVRRINIKPQVDEWAFRD-GRSIIVLSEGRLLNLGNATGHPSFVMSNSFSNQTIAQI 425 Query 434 ELWTKNDEYDNEVYRLPKHLDEKVARIHVEALGGHLTKLTKEQAEYLGVDVEGPYKPDHY 493 EL+TK EYD EVYRLPK LDEK+ARIHVEALGG LT+LTK+QAEY+GVDVEGPYKPDHY Sbjct 426 ELFTKYREYDREVYRLPKALDEKIARIHVEALGGELTRLTKDQAEYIGVDVEGPYKPDHY 485 Query 494 RY 495 RY Sbjct 486 RY 487 >gi|319949854|ref|ZP_08023866.1| S-adenosyl-L-homocysteine hydrolase [Dietzia cinnamea P4] gi|319436479|gb|EFV91587.1| S-adenosyl-L-homocysteine hydrolase [Dietzia cinnamea P4] Length=488 Score = 760 bits (1962), Expect = 0.0, Method: Compositional matrix adjust. Identities = 369/480 (77%), Positives = 417/480 (87%), Gaps = 3/480 (0%) Query 17 NGIDFKIADLSLADFGRKELRIAEHEMPGLMSLRREYAEVQPLKGARISGSLHMTVQTAV 76 NG++FK+ADLSLA+ GRK++R+AEHEMPGLM+LR EYA QPL GARI+GS+HMTVQTAV Sbjct 11 NGVEFKVADLSLAEAGRKQIRLAEHEMPGLMALREEYAAEQPLAGARIAGSIHMTVQTAV 70 Query 77 LIETLTALGAEVRWASCNIFSTQDHAAAAVVVGPHGTPDEPKGVPVFAWKGETLEEYWWA 136 LIETLTALGAEVRWASCNIFSTQD AAAAVVVGP GTP+EP+GVPVFAWKGETLEEYWW Sbjct 71 LIETLTALGAEVRWASCNIFSTQDEAAAAVVVGPEGTPEEPRGVPVFAWKGETLEEYWWC 130 Query 137 AEQMLTWPDPDKPANMILDDGGDATMLVLRGMQYEKAGVVPPAEEDDPAEWKVFLNLLRT 196 EQ++TWP + NMILDDGGDATMLV++G ++E+AG VP + AE KVF LLR Sbjct 131 TEQIMTWPGTEP--NMILDDGGDATMLVIKGKEFEQAGAVPSDDASWSAEEKVFHALLRE 188 Query 197 RFETDKDKWTKIAESVKGVTEETTTGVLRLYQFAAAGDLAFPAINVNDSVTKSKFDNKYG 256 + K+T IAESVKGVTEETTTGV RLY F A G L FPA+NVND+VTKSKFDNKYG Sbjct 189 SVPANPGKYTAIAESVKGVTEETTTGVHRLYHFHAEGVLPFPAMNVNDAVTKSKFDNKYG 248 Query 257 TRHSLIDGINRGTDALIGGKKVLICGYGDVGKGCAEAMKGQGARVSVTEIDPINALQAMM 316 TRHSL+DGINRGTDALIGGKK L+CGYGDVGKGCAEA+ GQGARV VTEIDPINALQAMM Sbjct 249 TRHSLLDGINRGTDALIGGKKALVCGYGDVGKGCAEALAGQGARVQVTEIDPINALQAMM 308 Query 317 EGFDVVTVEEAIGDADIVVTATGNKDIIMLEHIKAMKDHAILGNIGHFDNEIDMAGLERS 376 +GFDVVTV++AI DADIV+TATGNKDII EH+K MK+ AILGNIGHFDNEIDMAGLE + Sbjct 309 DGFDVVTVDQAIADADIVITATGNKDIITFEHMKRMKNKAILGNIGHFDNEIDMAGLESA 368 Query 377 -GATRVNVKPQVDLWTFGDTGRSIIVLSEGRLLNLGNATGHPSFVMSNSFANQTIAQIEL 435 G TR+N+KPQVD + F D GRSIIVLSEGRLLNLGNATGHPSFVMSNSF++Q IAQIEL Sbjct 369 EGVTRINIKPQVDEFVFDDDGRSIIVLSEGRLLNLGNATGHPSFVMSNSFSDQVIAQIEL 428 Query 436 WTKNDEYDNEVYRLPKHLDEKVARIHVEALGGHLTKLTKEQAEYLGVDVEGPYKPDHYRY 495 +TK D+Y V+ LPK LDEKVAR+HVEALGG LT+L K+QAEY+GVDVEGP+KPDHYRY Sbjct 429 FTKADQYPIGVHLLPKILDEKVARLHVEALGGTLTRLAKDQAEYIGVDVEGPFKPDHYRY 488 >gi|300789821|ref|YP_003770112.1| adenosylhomocysteinase [Amycolatopsis mediterranei U32] gi|299799335|gb|ADJ49710.1| adenosylhomocysteinase [Amycolatopsis mediterranei U32] gi|340531489|gb|AEK46694.1| S-adenosyl-L-homocysteine hydrolase [Amycolatopsis mediterranei S699] Length=490 Score = 753 bits (1943), Expect = 0.0, Method: Compositional matrix adjust. Identities = 359/481 (75%), Positives = 418/481 (87%), Gaps = 4/481 (0%) Query 16 RNGIDFKIADLSLADFGRKELRIAEHEMPGLMSLRREYAEVQPLKGARISGSLHMTVQTA 75 RNGI+F +ADL A+FGRKE+R+AEHEMPGLM+LRREYAEV PL+GAR+SGSLHMTVQTA Sbjct 13 RNGIEFAVADLEAAEFGRKEIRLAEHEMPGLMALRREYAEVYPLRGARVSGSLHMTVQTA 72 Query 76 VLIETLTALGAEVRWASCNIFSTQDHAAAAVVVGPHGTPDEPKGVPVFAWKGETLEEYWW 135 VLIETL ALGAEVRWASCNIFSTQDHAAAA+VVGPHGTP+EPKGVPVFAWKGE+LEEYWW Sbjct 73 VLIETLVALGAEVRWASCNIFSTQDHAAAAIVVGPHGTPEEPKGVPVFAWKGESLEEYWW 132 Query 136 AAEQMLTWPDPDKPANMILDDGGDATMLVLRGMQYEKAGVVPPAEEDDPAEWKVFLNLLR 195 E+MLTW D + P NMILDDGGDATMLV +G +YEK+GVVP +E+ E++VFL LLR Sbjct 133 CTERMLTW-DGEGP-NMILDDGGDATMLVHKGTEYEKSGVVPTPDENTSDEFRVFLELLR 190 Query 196 TRFETDKDKWTKIAESVKGVTEETTTGVLRLYQFAAAGDLAFPAINVNDSVTKSKFDNKY 255 +D KWTKI E ++GVTEETTTGVLRLYQ AAAG+L FPAINVND+VTKSKFDN+Y Sbjct 191 ASVASDTGKWTKIGEGIRGVTEETTTGVLRLYQLAAAGELLFPAINVNDAVTKSKFDNRY 250 Query 256 GTRHSLIDGINRGTDALIGGKKVLICGYGDVGKGCAEAMKGQGARVSVTEIDPINALQAM 315 G RHSLIDGINRGTD LIGGK ++CGYGDVGKG AE+++GQGARV VTEIDPI ALQA Sbjct 251 GIRHSLIDGINRGTDVLIGGKVAVVCGYGDVGKGAAESLRGQGARVIVTEIDPICALQAA 310 Query 316 MEGFDVVTVEEAIGDADIVVTATGNKDIIMLEHIKAMKDHAILGNIGHFDNEIDMAGLER 375 M+G+ V +E + +ADI++T TGNKD++++EH+ MK AILGNIGHFDNE+DMAGL R Sbjct 311 MDGYAVRKLESVLPEADIIITTTGNKDVVLVEHMAKMKHQAILGNIGHFDNELDMAGLAR 370 Query 376 -SGATRVNVKPQVDLWTFGDTGRSIIVLSEGRLLNLGNATGHPSFVMSNSFANQTIAQIE 434 G ++N+KPQVD W F + G +IIVLSEGRLLNLGNATGHPSFVMSNSF+NQ IAQIE Sbjct 371 YPGIRKINIKPQVDEWIFPN-GNTIIVLSEGRLLNLGNATGHPSFVMSNSFSNQVIAQIE 429 Query 435 LWTKNDEYDNEVYRLPKHLDEKVARIHVEALGGHLTKLTKEQAEYLGVDVEGPYKPDHYR 494 L+TK++EYD EV+RLPK LDEKVARIH++ALGG LTKLTKEQAEY+ VDVEGP+KP+HYR Sbjct 430 LFTKHEEYDKEVFRLPKKLDEKVARIHLDALGGELTKLTKEQAEYIDVDVEGPFKPEHYR 489 Query 495 Y 495 Y Sbjct 490 Y 490 >gi|258654379|ref|YP_003203535.1| S-adenosyl-L-homocysteine hydrolase [Nakamurella multipartita DSM 44233] gi|258557604|gb|ACV80546.1| adenosylhomocysteinase [Nakamurella multipartita DSM 44233] Length=498 Score = 740 bits (1910), Expect = 0.0, Method: Compositional matrix adjust. Identities = 358/497 (73%), Positives = 412/497 (83%), Gaps = 5/497 (1%) Query 2 TGNLVTKNSLTPDVRNGIDFKIADLSLADFGRKELRIAEHEMPGLMSLRREYAEVQPLKG 61 T + ++ +L D +D+K+A ++LADFGRKE+ +AEHEMPGLM+LRREYAEVQPL G Sbjct 4 TTSTLSDLNLVADRSGDLDYKVASMALADFGRKEITLAEHEMPGLMALRREYAEVQPLAG 63 Query 62 ARISGSLHMTVQTAVLIETLTALGAEVRWASCNIFSTQDHAAAAVVVGPHGTPDEPKGVP 121 ARISGSLHMTVQTAVLIETL LGA+VRWASCNIFSTQDHAAAAVVVG +GT +EPKG P Sbjct 64 ARISGSLHMTVQTAVLIETLVELGADVRWASCNIFSTQDHAAAAVVVGKYGTVEEPKGTP 123 Query 122 VFAWKGETLEEYWWAAEQMLTWPDPDKPANMILDDGGDATMLVLRGMQYEKAGVVPPAEE 181 VFAWKGETL EYWW EQML WPD P NMILDDGGDAT+LV +G+ YEK GV+P E Sbjct 124 VFAWKGETLPEYWWCTEQMLRWPDGQGP-NMILDDGGDATLLVHKGVAYEKTGVIPSINE 182 Query 182 DDPA---EWKVFLNLLRTRFETDKDKWTKIAESVKGVTEETTTGVLRLYQFAAAGDLAFP 238 DDP E+ V L+ LR D WT+ A S+ GVTEETTTGV RLYQ AAAG+L FP Sbjct 183 DDPEYSEEYAVILDFLRASLAADPQYWTRTAPSIIGVTEETTTGVNRLYQLAAAGELLFP 242 Query 239 AINVNDSVTKSKFDNKYGTRHSLIDGINRGTDALIGGKKVLICGYGDVGKGCAEAMKGQG 298 AINVNDSVTKSKFDNKYG RHSLIDGINRGTD LIGGK L+ GYGDVGKG AE+++GQG Sbjct 243 AINVNDSVTKSKFDNKYGIRHSLIDGINRGTDVLIGGKVALVAGYGDVGKGAAESLRGQG 302 Query 299 ARVSVTEIDPINALQAMMEGFDVVTVEEAIGDADIVVTATGNKDIIMLEHIKAMKDHAIL 358 ARV V EIDPI ALQA+M+GF+V TV++A+ AD+++T TGNKDII + H+ MK AIL Sbjct 303 ARVVVAEIDPICALQALMDGFEVSTVDKAVERADLIITTTGNKDIITVAHMSRMKHQAIL 362 Query 359 GNIGHFDNEIDMAGLERSGATRVNVKPQVDLWTFGDTGRSIIVLSEGRLLNLGNATGHPS 418 GNIGHFDNEIDMAGL RSGA+++ +KPQVD W F D G +IIVLS GRLLNLGNATGHPS Sbjct 363 GNIGHFDNEIDMAGLARSGASKIEIKPQVDEWRFAD-GHTIIVLSAGRLLNLGNATGHPS 421 Query 419 FVMSNSFANQTIAQIELWTKNDEYDNEVYRLPKHLDEKVARIHVEALGGHLTKLTKEQAE 478 FVMS SF+NQ IAQ+EL+TK +E+D EVYRLPKHLDEKVA+IHVEALGG LTKL+K+QAE Sbjct 422 FVMSTSFSNQVIAQLELFTKPNEWDKEVYRLPKHLDEKVAKIHVEALGGELTKLSKDQAE 481 Query 479 YLGVDVEGPYKPDHYRY 495 YLGVDVEGP+KP+HYRY Sbjct 482 YLGVDVEGPFKPEHYRY 498 >gi|213964853|ref|ZP_03393052.1| adenosylhomocysteinase [Corynebacterium amycolatum SK46] gi|213952389|gb|EEB63772.1| adenosylhomocysteinase [Corynebacterium amycolatum SK46] Length=484 Score = 730 bits (1885), Expect = 0.0, Method: Compositional matrix adjust. Identities = 352/481 (74%), Positives = 404/481 (84%), Gaps = 6/481 (1%) Query 19 IDFKIADLSLADFGRKELRIAEHEMPGLMSLRREYAEVQPLKGARISGSLHMTVQTAVLI 78 IDFK+ADLSLA+ GR ++R+AEHEMPGLM+LR EYAE QPL GARISGS+HMTVQTAVLI Sbjct 6 IDFKVADLSLAEAGRHQIRLAEHEMPGLMALREEYAEQQPLAGARISGSIHMTVQTAVLI 65 Query 79 ETLTALGAEVRWASCNIFSTQDHAAAAVVVGPHGTPDEPKGVPVFAWKGETLEEYWWAAE 138 ETLTALGA+VRWASCNIFSTQD AAAAVVVG +GTP++P+GVPVFAWKGETLEEYWW + Sbjct 66 ETLTALGAQVRWASCNIFSTQDEAAAAVVVGRNGTPEDPQGVPVFAWKGETLEEYWWCLD 125 Query 139 QMLTWPDPDKPANMILDDGGDATMLVLRGMQYEKAGVVPPAEEDDPAEWKVFLNLLRTRF 198 ++ W D D ANMILDDGGDATM V++GM++E AG+VPPAEE D E+ F ++LR Sbjct 126 RIFDWGDED--ANMILDDGGDATMAVIKGMEFEDAGLVPPAEESDSDEFIAFKDMLRASL 183 Query 199 ETDKDKWTKIAESVKGVTEETTTGVLRLYQFAAAGDLAFPAINVNDSVTKSKFDNKYGTR 258 E D +W +IA+SVKGVTEETTTGV RLY FA G L FPA+NVND+VTKSKFDNKYGTR Sbjct 184 EKDAGRWHRIAKSVKGVTEETTTGVHRLYHFAEQGVLPFPAMNVNDAVTKSKFDNKYGTR 243 Query 259 HSLIDGINRGTDALIGGKKVLICGYGDVGKGCAEAMKGQGARVSVTEIDPINALQAMMEG 318 HSL+DGINRGTD L+GGK VL+CGYGDVGKGCAEA+ GQGARV VTE DPINALQA+M+G Sbjct 244 HSLLDGINRGTDMLVGGKNVLVCGYGDVGKGCAEALAGQGARVQVTEADPINALQALMDG 303 Query 319 FDVVTVEEAIGDADIVVTATGNKDIIMLEHIKAMKDHAILGNIGHFDNEIDMAGL-ERSG 377 FDVV E I D DIV+TATGNK +I EH++ MK+HA+LGNIGHFDNEIDM L R Sbjct 304 FDVVATESVIADVDIVITATGNKGVITFEHMQQMKNHALLGNIGHFDNEIDMHSLHHRDD 363 Query 378 ATRVNVKPQVDLWTFGDTG---RSIIVLSEGRLLNLGNATGHPSFVMSNSFANQTIAQIE 434 RV +KPQV + F RS+IVLSEGRLLNLGNATGHPSFVMS SFA+QTIAQIE Sbjct 364 VRRVEIKPQVTEYIFPHADGEERSLIVLSEGRLLNLGNATGHPSFVMSTSFADQTIAQIE 423 Query 435 LWTKNDEYDNEVYRLPKHLDEKVARIHVEALGGHLTKLTKEQAEYLGVDVEGPYKPDHYR 494 L+ D+YDN V+RLPK LDEKVARIHVEALGG +T+L+KEQAEY+GVDVEGPYKP+HYR Sbjct 424 LYCNGDKYDNTVHRLPKILDEKVARIHVEALGGEITRLSKEQAEYIGVDVEGPYKPEHYR 483 Query 495 Y 495 Y Sbjct 484 Y 484 >gi|334696306|gb|AEG81103.1| adenosylhomocysteinase [Corynebacterium ulcerans 809] Length=479 Score = 730 bits (1885), Expect = 0.0, Method: Compositional matrix adjust. Identities = 356/478 (75%), Positives = 399/478 (84%), Gaps = 3/478 (0%) Query 19 IDFKIADLSLADFGRKELRIAEHEMPGLMSLRREYAEVQPLKGARISGSLHMTVQTAVLI 78 DFK+ DLSLA+ GR ++R+AEHEMPGLM LR EY E QPL GARI+GS+HMTVQTAVLI Sbjct 4 FDFKVKDLSLAEAGRHQIRLAEHEMPGLMQLREEYREEQPLAGARITGSIHMTVQTAVLI 63 Query 79 ETLTALGAEVRWASCNIFSTQDHAAAAVVVGPHGTPDEPKGVPVFAWKGETLEEYWWAAE 138 ETL ALGAEVRWASCNIFSTQD AAAAVVVGP GT D P+GVPVFAWKGETL+EYW Sbjct 64 ETLVALGAEVRWASCNIFSTQDEAAAAVVVGPEGTVDNPQGVPVFAWKGETLQEYWDCVH 123 Query 139 QMLTWPDPDKPANMILDDGGDATMLVLRGMQYEKAGVVPPAEEDDPAEWKVFLNLLRTRF 198 ++ WP P NMILDDGGDATM V+RG QYE+AGVVPP+EE D E++ FL +LR Sbjct 124 KIFAWPGEQLP-NMILDDGGDATMAVIRGRQYEQAGVVPPSEEGDSDEYQAFLEMLRATL 182 Query 199 ETDKDKWTKIAESVKGVTEETTTGVLRLYQFAAAGDLAFPAINVNDSVTKSKFDNKYGTR 258 E+D WT IA SVKGVTEETTTGV RLY FA G L FPA+NVND+VTKSKFDNKYGTR Sbjct 183 ESDPGMWTAIASSVKGVTEETTTGVHRLYHFAEEGVLPFPAMNVNDAVTKSKFDNKYGTR 242 Query 259 HSLIDGINRGTDALIGGKKVLICGYGDVGKGCAEAMKGQGARVSVTEIDPINALQAMMEG 318 HSLIDGINR TD L+GGK VLICGYGDVGKGCAEAM GQGARV VTE DPINALQA+M+G Sbjct 243 HSLIDGINRATDMLMGGKNVLICGYGDVGKGCAEAMAGQGARVKVTEADPINALQALMDG 302 Query 319 FDVVTVEEAIGDADIVVTATGNKDIIMLEHIKAMKDHAILGNIGHFDNEIDMAG-LERSG 377 F VVTV++AI +ADIV+TATGN II +H+ MKDHA+LGNIGHFDNEIDMA L R+ Sbjct 303 FSVVTVDQAISEADIVITATGNMGIISFDHMLKMKDHAVLGNIGHFDNEIDMASLLHRND 362 Query 378 ATRVNVKPQVDLWTFGDTGRSIIVLSEGRLLNLGNATGHPSFVMSNSFANQTIAQIELWT 437 +RV +KPQVD +T + G +IIVLSEGRLLNLGNATGHPSFVMS SFA+QTIAQIEL+ Sbjct 363 VSRVTIKPQVDEFTLPN-GNAIIVLSEGRLLNLGNATGHPSFVMSTSFADQTIAQIELFR 421 Query 438 KNDEYDNEVYRLPKHLDEKVARIHVEALGGHLTKLTKEQAEYLGVDVEGPYKPDHYRY 495 + Y NEVYRLPK LDEKVARIHVEALGGH+T+LTKEQAEY+GVDV GPYKP+HYRY Sbjct 422 NDGRYHNEVYRLPKILDEKVARIHVEALGGHITELTKEQAEYIGVDVAGPYKPEHYRY 479 >gi|19551979|ref|NP_599981.1| S-adenosyl-L-homocysteine hydrolase [Corynebacterium glutamicum ATCC 13032] gi|62389640|ref|YP_225042.1| S-adenosyl-L-homocysteine hydrolase [Corynebacterium glutamicum ATCC 13032] gi|145294915|ref|YP_001137736.1| S-adenosyl-L-homocysteine hydrolase [Corynebacterium glutamicum R] gi|167016540|sp|A4QC87.1|SAHH_CORGB RecName: Full=Adenosylhomocysteinase; AltName: Full=S-adenosyl-L-homocysteine hydrolase; Short=AdoHcyase gi|41324975|emb|CAF19456.1| Adenosylhomocysteinase [Corynebacterium glutamicum ATCC 13032] gi|140844835|dbj|BAF53834.1| hypothetical protein [Corynebacterium glutamicum R] gi|344043748|gb|EGV39436.1| S-adenosyl-L-homocysteine hydrolase [Corynebacterium glutamicum S9114] Length=478 Score = 729 bits (1881), Expect = 0.0, Method: Compositional matrix adjust. Identities = 357/478 (75%), Positives = 405/478 (85%), Gaps = 5/478 (1%) Query 19 IDFKIADLSLADFGRKELRIAEHEMPGLMSLRREYAEVQPLKGARISGSLHMTVQTAVLI 78 +DFK+ADLSLA+ GR ++R+AE+EMPGLM LR+E+A+ QPLKGARI+GS+HMTVQTAVLI Sbjct 5 MDFKVADLSLAEAGRHQIRLAEYEMPGLMQLRKEFADEQPLKGARIAGSIHMTVQTAVLI 64 Query 79 ETLTALGAEVRWASCNIFSTQDHAAAAVVVGPHGTPDEPKGVPVFAWKGETLEEYWWAAE 138 ETLTALGAEVRWASCNIFSTQD AAAA+VVG GT +EP GVPVFAWKGE+LEEYWW Sbjct 65 ETLTALGAEVRWASCNIFSTQDEAAAAIVVGS-GTVEEPAGVPVFAWKGESLEEYWWCIN 123 Query 139 QMLTWPDPDKPANMILDDGGDATMLVLRGMQYEKAGVVPPAEEDDPAEWKVFLNLLRTRF 198 Q+ +W D + NMILDDGGDATM V+RG +YE+AG+VPPAE +D E+ FL +LR Sbjct 124 QIFSWGD--ELPNMILDDGGDATMAVIRGREYEQAGLVPPAEANDSDEYIAFLGMLREVL 181 Query 199 ETDKDKWTKIAESVKGVTEETTTGVLRLYQFAAAGDLAFPAINVNDSVTKSKFDNKYGTR 258 + KW KIAE+VKGVTEETTTGV RLY FA G L FPA+NVND+VTKSKFDNKYGTR Sbjct 182 AAEPGKWGKIAEAVKGVTEETTTGVHRLYHFAEEGVLPFPAMNVNDAVTKSKFDNKYGTR 241 Query 259 HSLIDGINRGTDALIGGKKVLICGYGDVGKGCAEAMKGQGARVSVTEIDPINALQAMMEG 318 HSLIDGINR TD L+GGK VL+CGYGDVGKGCAEA GQGARV VTE DPINALQA+M+G Sbjct 242 HSLIDGINRATDMLMGGKNVLVCGYGDVGKGCAEAFDGQGARVKVTEADPINALQALMDG 301 Query 319 FDVVTVEEAIGDADIVVTATGNKDIIMLEHIKAMKDHAILGNIGHFDNEIDMAG-LERSG 377 + VVTV+EAI DADIV+TATGNKDII E + MKDHA+LGNIGHFDNEIDM L R Sbjct 302 YSVVTVDEAIEDADIVITATGNKDIISFEQMLKMKDHALLGNIGHFDNEIDMHSLLHRDD 361 Query 378 ATRVNVKPQVDLWTFGDTGRSIIVLSEGRLLNLGNATGHPSFVMSNSFANQTIAQIELWT 437 TR +KPQVD +TF TGRSIIVLSEGRLLNLGNATGHPSFVMSNSFA+QTIAQIEL+ Sbjct 362 VTRTTIKPQVDEFTF-STGRSIIVLSEGRLLNLGNATGHPSFVMSNSFADQTIAQIELFQ 420 Query 438 KNDEYDNEVYRLPKHLDEKVARIHVEALGGHLTKLTKEQAEYLGVDVEGPYKPDHYRY 495 +Y+NEVYRLPK LDEKVARIHVEALGG LT+LTKEQAEY+GVDV GP+KP+HYRY Sbjct 421 NEGQYENEVYRLPKVLDEKVARIHVEALGGQLTELTKEQAEYIGVDVAGPFKPEHYRY 478 >gi|29336780|sp|Q8NSC4.1|SAHH_CORGL RecName: Full=Adenosylhomocysteinase; AltName: Full=S-adenosyl-L-homocysteine hydrolase; Short=AdoHcyase gi|21323518|dbj|BAB98145.1| S-adenosylhomocysteine hydrolase [Corynebacterium glutamicum ATCC 13032] Length=474 Score = 728 bits (1880), Expect = 0.0, Method: Compositional matrix adjust. Identities = 357/478 (75%), Positives = 405/478 (85%), Gaps = 5/478 (1%) Query 19 IDFKIADLSLADFGRKELRIAEHEMPGLMSLRREYAEVQPLKGARISGSLHMTVQTAVLI 78 +DFK+ADLSLA+ GR ++R+AE+EMPGLM LR+E+A+ QPLKGARI+GS+HMTVQTAVLI Sbjct 1 MDFKVADLSLAEAGRHQIRLAEYEMPGLMQLRKEFADEQPLKGARIAGSIHMTVQTAVLI 60 Query 79 ETLTALGAEVRWASCNIFSTQDHAAAAVVVGPHGTPDEPKGVPVFAWKGETLEEYWWAAE 138 ETLTALGAEVRWASCNIFSTQD AAAA+VVG GT +EP GVPVFAWKGE+LEEYWW Sbjct 61 ETLTALGAEVRWASCNIFSTQDEAAAAIVVGS-GTVEEPAGVPVFAWKGESLEEYWWCIN 119 Query 139 QMLTWPDPDKPANMILDDGGDATMLVLRGMQYEKAGVVPPAEEDDPAEWKVFLNLLRTRF 198 Q+ +W D + NMILDDGGDATM V+RG +YE+AG+VPPAE +D E+ FL +LR Sbjct 120 QIFSWGD--ELPNMILDDGGDATMAVIRGREYEQAGLVPPAEANDSDEYIAFLGMLREVL 177 Query 199 ETDKDKWTKIAESVKGVTEETTTGVLRLYQFAAAGDLAFPAINVNDSVTKSKFDNKYGTR 258 + KW KIAE+VKGVTEETTTGV RLY FA G L FPA+NVND+VTKSKFDNKYGTR Sbjct 178 AAEPGKWGKIAEAVKGVTEETTTGVHRLYHFAEEGVLPFPAMNVNDAVTKSKFDNKYGTR 237 Query 259 HSLIDGINRGTDALIGGKKVLICGYGDVGKGCAEAMKGQGARVSVTEIDPINALQAMMEG 318 HSLIDGINR TD L+GGK VL+CGYGDVGKGCAEA GQGARV VTE DPINALQA+M+G Sbjct 238 HSLIDGINRATDMLMGGKNVLVCGYGDVGKGCAEAFDGQGARVKVTEADPINALQALMDG 297 Query 319 FDVVTVEEAIGDADIVVTATGNKDIIMLEHIKAMKDHAILGNIGHFDNEIDMAG-LERSG 377 + VVTV+EAI DADIV+TATGNKDII E + MKDHA+LGNIGHFDNEIDM L R Sbjct 298 YSVVTVDEAIEDADIVITATGNKDIISFEQMLKMKDHALLGNIGHFDNEIDMHSLLHRDD 357 Query 378 ATRVNVKPQVDLWTFGDTGRSIIVLSEGRLLNLGNATGHPSFVMSNSFANQTIAQIELWT 437 TR +KPQVD +TF TGRSIIVLSEGRLLNLGNATGHPSFVMSNSFA+QTIAQIEL+ Sbjct 358 VTRTTIKPQVDEFTF-STGRSIIVLSEGRLLNLGNATGHPSFVMSNSFADQTIAQIELFQ 416 Query 438 KNDEYDNEVYRLPKHLDEKVARIHVEALGGHLTKLTKEQAEYLGVDVEGPYKPDHYRY 495 +Y+NEVYRLPK LDEKVARIHVEALGG LT+LTKEQAEY+GVDV GP+KP+HYRY Sbjct 417 NEGQYENEVYRLPKVLDEKVARIHVEALGGQLTELTKEQAEYIGVDVAGPFKPEHYRY 474 >gi|337290185|ref|YP_004629206.1| adenosylhomocysteinase [Corynebacterium ulcerans BR-AD22] gi|334698491|gb|AEG83287.1| adenosylhomocysteinase [Corynebacterium ulcerans BR-AD22] Length=479 Score = 727 bits (1876), Expect = 0.0, Method: Compositional matrix adjust. Identities = 355/478 (75%), Positives = 398/478 (84%), Gaps = 3/478 (0%) Query 19 IDFKIADLSLADFGRKELRIAEHEMPGLMSLRREYAEVQPLKGARISGSLHMTVQTAVLI 78 DFK+ DLSLA+ GR ++R+AEHEMPGLM LR EY E QPL GARI+GS+HMTVQTAVLI Sbjct 4 FDFKVKDLSLAEAGRHQIRLAEHEMPGLMQLREEYREEQPLAGARITGSIHMTVQTAVLI 63 Query 79 ETLTALGAEVRWASCNIFSTQDHAAAAVVVGPHGTPDEPKGVPVFAWKGETLEEYWWAAE 138 ETL ALGAEVRWASCNIFSTQD AAAAVVVGP GT D P+GVPVFAWKGETL+EYW Sbjct 64 ETLVALGAEVRWASCNIFSTQDEAAAAVVVGPEGTVDNPQGVPVFAWKGETLQEYWDCVH 123 Query 139 QMLTWPDPDKPANMILDDGGDATMLVLRGMQYEKAGVVPPAEEDDPAEWKVFLNLLRTRF 198 ++ WP P NMILDDGGDATM V+RG QYE+AGVVPP+EE D E++ FL +LR Sbjct 124 KIFAWPGEQLP-NMILDDGGDATMAVIRGRQYEQAGVVPPSEEGDSDEYQAFLEMLRATL 182 Query 199 ETDKDKWTKIAESVKGVTEETTTGVLRLYQFAAAGDLAFPAINVNDSVTKSKFDNKYGTR 258 E+D WT IA SVKGVTEETTTGV RLY FA G L FPA+NVND+VTKSKFDNKYGTR Sbjct 183 ESDPGMWTAIASSVKGVTEETTTGVHRLYHFAEEGVLPFPAMNVNDAVTKSKFDNKYGTR 242 Query 259 HSLIDGINRGTDALIGGKKVLICGYGDVGKGCAEAMKGQGARVSVTEIDPINALQAMMEG 318 HSLIDGINR TD L+GGK VLICGYGDVGKGCAEAM GQGARV VTE DPINALQA+M+G Sbjct 243 HSLIDGINRATDMLMGGKNVLICGYGDVGKGCAEAMAGQGARVKVTEADPINALQALMDG 302 Query 319 FDVVTVEEAIGDADIVVTATGNKDIIMLEHIKAMKDHAILGNIGHFDNEIDMAG-LERSG 377 F VVTV++AI +ADIV+TATGN II +H+ MKDHA+LGNIGHFDNEIDMA L R+ Sbjct 303 FSVVTVDQAISEADIVITATGNMGIISFDHMLKMKDHAVLGNIGHFDNEIDMASLLHRND 362 Query 378 ATRVNVKPQVDLWTFGDTGRSIIVLSEGRLLNLGNATGHPSFVMSNSFANQTIAQIELWT 437 +RV +KPQVD +T + G +IIVLSEGRLLNLGNATGHPSFVMS SFA+QTIAQIEL+ Sbjct 363 VSRVTIKPQVDEFTLPN-GNAIIVLSEGRLLNLGNATGHPSFVMSTSFADQTIAQIELFR 421 Query 438 KNDEYDNEVYRLPKHLDEKVARIHVEALGGHLTKLTKEQAEYLGVDVEGPYKPDHYRY 495 + Y NEVYRLPK LDEKVARIHVEALGG +T+LTKEQAEY+GVDV GPYKP+HYRY Sbjct 422 NDGRYRNEVYRLPKILDEKVARIHVEALGGRITELTKEQAEYIGVDVAGPYKPEHYRY 479 >gi|300857933|ref|YP_003782916.1| adenosylhomocysteinase [Corynebacterium pseudotuberculosis FRC41] gi|300685387|gb|ADK28309.1| adenosylhomocysteinase [Corynebacterium pseudotuberculosis FRC41] gi|302205662|gb|ADL10004.1| S-adenosyl-L-homocysteine hydrolase [Corynebacterium pseudotuberculosis C231] gi|302330213|gb|ADL20407.1| S-adenosyl-L-homocysteine hydrolase [Corynebacterium pseudotuberculosis 1002] gi|308275897|gb|ADO25796.1| S-adenosyl-L-homocysteine hydrolase [Corynebacterium pseudotuberculosis I19] gi|341824327|gb|AEK91848.1| S-adenosyl-L-homocysteine hydrolase [Corynebacterium pseudotuberculosis PAT10] Length=479 Score = 724 bits (1868), Expect = 0.0, Method: Compositional matrix adjust. Identities = 354/478 (75%), Positives = 397/478 (84%), Gaps = 3/478 (0%) Query 19 IDFKIADLSLADFGRKELRIAEHEMPGLMSLRREYAEVQPLKGARISGSLHMTVQTAVLI 78 DFK+ DLSLA+ GR ++R+AE+EMPGLM LR EY E QPL GARI+GS+HMTVQTAVLI Sbjct 4 FDFKVKDLSLAEAGRHQIRLAEYEMPGLMQLREEYREEQPLAGARITGSIHMTVQTAVLI 63 Query 79 ETLTALGAEVRWASCNIFSTQDHAAAAVVVGPHGTPDEPKGVPVFAWKGETLEEYWWAAE 138 ETL ALGAEVRWASCNIFSTQD AAAAVVVGP GT D P+GVPVFAWKGETL+EYW Sbjct 64 ETLVALGAEVRWASCNIFSTQDEAAAAVVVGPEGTVDNPQGVPVFAWKGETLQEYWDCVH 123 Query 139 QMLTWPDPDKPANMILDDGGDATMLVLRGMQYEKAGVVPPAEEDDPAEWKVFLNLLRTRF 198 ++ WP D+ NMILDDGGDATM V+RG QYE+AGVVPP EE D E++ FL +LR Sbjct 124 KIFAWPG-DQLPNMILDDGGDATMAVIRGQQYEQAGVVPPGEEGDSDEYQAFLEMLRATL 182 Query 199 ETDKDKWTKIAESVKGVTEETTTGVLRLYQFAAAGDLAFPAINVNDSVTKSKFDNKYGTR 258 E+D WT IA SVKGVTEETTTGV RLY FA G L FPA+NVND+VTKSKFDNKYGTR Sbjct 183 ESDPGMWTAIASSVKGVTEETTTGVHRLYHFAEEGVLPFPAMNVNDAVTKSKFDNKYGTR 242 Query 259 HSLIDGINRGTDALIGGKKVLICGYGDVGKGCAEAMKGQGARVSVTEIDPINALQAMMEG 318 HSLIDGINR TD L+GGK VLICGYGDVGKGCAEAM GQGARV VTE DPINALQA+M+G Sbjct 243 HSLIDGINRATDMLMGGKNVLICGYGDVGKGCAEAMAGQGARVKVTEADPINALQALMDG 302 Query 319 FDVVTVEEAIGDADIVVTATGNKDIIMLEHIKAMKDHAILGNIGHFDNEIDMAG-LERSG 377 F VVTV++AI +ADIV+TATGN II E + MKDHA+LGNIGHFDNEIDMA L R+ Sbjct 303 FPVVTVDQAISEADIVITATGNMGIISFEQMLKMKDHAVLGNIGHFDNEIDMASLLHRND 362 Query 378 ATRVNVKPQVDLWTFGDTGRSIIVLSEGRLLNLGNATGHPSFVMSNSFANQTIAQIELWT 437 +RV +KPQVD +T + G +IIVLSEGRLLNLGNATGHPSFVMS SFA+QTIAQIEL+ Sbjct 363 VSRVTIKPQVDEFTLPN-GNAIIVLSEGRLLNLGNATGHPSFVMSTSFADQTIAQIELFQ 421 Query 438 KNDEYDNEVYRLPKHLDEKVARIHVEALGGHLTKLTKEQAEYLGVDVEGPYKPDHYRY 495 + Y NEVYRLPK LDEKVARIHVEALGG +T+LTKEQAEY+GVDV GPYKP+HYRY Sbjct 422 NDGRYRNEVYRLPKILDEKVARIHVEALGGEITELTKEQAEYIGVDVAGPYKPEHYRY 479 >gi|330465911|ref|YP_004403654.1| S-adenosyl-L-homocysteine hydrolase [Verrucosispora maris AB-18-032] gi|328808882|gb|AEB43054.1| S-adenosyl-L-homocysteine hydrolase [Verrucosispora maris AB-18-032] Length=499 Score = 723 bits (1865), Expect = 0.0, Method: Compositional matrix adjust. Identities = 348/477 (73%), Positives = 398/477 (84%), Gaps = 3/477 (0%) Query 20 DFKIADLSLADFGRKELRIAEHEMPGLMSLRREYAEVQPLKGARISGSLHMTVQTAVLIE 79 DF++ADLSLA+FGRKE+R+AEHEMPGLM++RRE+AE QPL GARI+GSLHMT+QTAVLIE Sbjct 25 DFRVADLSLAEFGRKEIRLAEHEMPGLMAIRREFAEAQPLAGARITGSLHMTIQTAVLIE 84 Query 80 TLTALGAEVRWASCNIFSTQDHAAAAVVVGPHGTPDEPKGVPVFAWKGETLEEYWWAAEQ 139 TL ALGAEVRWASCNIFSTQDHAAAA+VVGP GTPD P GVPV+AWKGETL+EYWW EQ Sbjct 85 TLVALGAEVRWASCNIFSTQDHAAAAIVVGPDGTPDAPAGVPVYAWKGETLQEYWWCTEQ 144 Query 140 MLTWPDPDKPANMILDDGGDATMLVLRGMQYEKAGVVPPAEEDDPAEWKVFLNLLRTRFE 199 +L WPD P NMILDDGGDAT+LV +G+++EKAGVVPP E D E+ V L LL Sbjct 145 VLDWPDGQGP-NMILDDGGDATLLVHKGVEFEKAGVVPPVESADSEEYAVILGLLHRSLA 203 Query 200 TDKDKWTKIAESVKGVTEETTTGVLRLYQFAAAGDLAFPAINVNDSVTKSKFDNKYGTRH 259 D +WT+IA ++KGVTEETTTGV RLY+ AG L FPAINVNDSVTKSKFDNKYG RH Sbjct 204 EDGQRWTRIAATIKGVTEETTTGVHRLYEMHRAGTLLFPAINVNDSVTKSKFDNKYGCRH 263 Query 260 SLIDGINRGTDALIGGKKVLICGYGDVGKGCAEAMKGQGARVSVTEIDPINALQAMMEGF 319 SLIDGINR TD LIGGK ++ GYGDVGKGCAE+++GQGARV VTE+DPI ALQA M+G+ Sbjct 264 SLIDGINRATDVLIGGKMAVVLGYGDVGKGCAESLRGQGARVVVTEVDPICALQAAMDGY 323 Query 320 DVVTVEEAIGDADIVVTATGNKDIIMLEHIKAMKDHAILGNIGHFDNEIDMAGL-ERSGA 378 V T+++ + ADI +TATG D+I EH+ MK AI+GNIGHFDNEIDMAGL +RS Sbjct 324 QVATLDDVVEIADIFITATGCFDVITNEHMARMKHQAIVGNIGHFDNEIDMAGLAKRSDV 383 Query 379 TRVNVKPQVDLWTFGDTGRSIIVLSEGRLLNLGNATGHPSFVMSNSFANQTIAQIELWTK 438 TR N+KPQVDLW F D G +IIVLSEGRLLNLGNATGHPSFVMSNSFANQTIAQIEL+TK Sbjct 384 TRENIKPQVDLWKF-DDGHAIIVLSEGRLLNLGNATGHPSFVMSNSFANQTIAQIELFTK 442 Query 439 NDEYDNEVYRLPKHLDEKVARIHVEALGGHLTKLTKEQAEYLGVDVEGPYKPDHYRY 495 +EY VY LPKHLDEKVAR+H+ ALG L+ LTKEQA YLGV VEGP+KPDHYRY Sbjct 443 TEEYPIGVYVLPKHLDEKVARLHLAALGAKLSTLTKEQAAYLGVAVEGPFKPDHYRY 499 >gi|25027323|ref|NP_737377.1| S-adenosyl-L-homocysteine hydrolase [Corynebacterium efficiens YS-314] gi|259506539|ref|ZP_05749441.1| adenosylhomocysteinase [Corynebacterium efficiens YS-314] gi|32171658|sp|Q8FRJ4.1|SAHH_COREF RecName: Full=Adenosylhomocysteinase; AltName: Full=S-adenosyl-L-homocysteine hydrolase; Short=AdoHcyase gi|23492604|dbj|BAC17577.1| putative adenosylhomocysteinase [Corynebacterium efficiens YS-314] gi|259165959|gb|EEW50513.1| adenosylhomocysteinase [Corynebacterium efficiens YS-314] Length=478 Score = 721 bits (1862), Expect = 0.0, Method: Compositional matrix adjust. Identities = 354/477 (75%), Positives = 405/477 (85%), Gaps = 5/477 (1%) Query 20 DFKIADLSLADFGRKELRIAEHEMPGLMSLRREYAEVQPLKGARISGSLHMTVQTAVLIE 79 DFK+ADLSLA+ GR ++R+AE+EMPGLM LRREYAE QPLKGARI+GS+HMTVQTAVLIE Sbjct 6 DFKVADLSLAEAGRHQIRLAEYEMPGLMQLRREYAEEQPLKGARIAGSIHMTVQTAVLIE 65 Query 80 TLTALGAEVRWASCNIFSTQDHAAAAVVVGPHGTPDEPKGVPVFAWKGETLEEYWWAAEQ 139 TLTALGAEVRWASCNIFSTQD AAAA+VVG GTP++P+GVPVFAWKGETL+EYWW Q Sbjct 66 TLTALGAEVRWASCNIFSTQDEAAAAIVVG-DGTPEDPQGVPVFAWKGETLDEYWWCINQ 124 Query 140 MLTWPDPDKPANMILDDGGDATMLVLRGMQYEKAGVVPPAEEDDPAEWKVFLNLLRTRFE 199 + +W + + P NMILDDGGDATM V+RG +YEKAGVVP E +D E+ FL +LR Sbjct 125 IFSW-EGELP-NMILDDGGDATMAVIRGREYEKAGVVPQPEANDSDEYIAFLGMLREVLA 182 Query 200 TDKDKWTKIAESVKGVTEETTTGVLRLYQFAAAGDLAFPAINVNDSVTKSKFDNKYGTRH 259 + DKWT++A+S+KGVTEETTTGV RLY FA G L FPA+NVND+VTKSKFDNKYGTRH Sbjct 183 EEPDKWTRLADSIKGVTEETTTGVHRLYHFAEEGVLPFPAMNVNDAVTKSKFDNKYGTRH 242 Query 260 SLIDGINRGTDALIGGKKVLICGYGDVGKGCAEAMKGQGARVSVTEIDPINALQAMMEGF 319 SLIDGINR TD L+GGK VL+CGYGDVGKGCAEA GQGARV VTE DPINALQA+M+G+ Sbjct 243 SLIDGINRATDMLMGGKNVLVCGYGDVGKGCAEAFDGQGARVRVTEADPINALQALMDGY 302 Query 320 DVVTVEEAIGDADIVVTATGNKDIIMLEHIKAMKDHAILGNIGHFDNEIDMAG-LERSGA 378 VVTV+EAI DADIV+TATGNKDII E + MKDHA+LGNIGHFDNEIDM L R Sbjct 303 SVVTVDEAIADADIVITATGNKDIISYEQMLKMKDHALLGNIGHFDNEIDMHSLLHRDDV 362 Query 379 TRVNVKPQVDLWTFGDTGRSIIVLSEGRLLNLGNATGHPSFVMSNSFANQTIAQIELWTK 438 R +KPQVD +TF + G+SIIVLSEGRLLNLGNATGHPSFVMS SFA+QTIAQIEL+ Sbjct 363 IRTTIKPQVDEFTFPN-GKSIIVLSEGRLLNLGNATGHPSFVMSTSFADQTIAQIELFQN 421 Query 439 NDEYDNEVYRLPKHLDEKVARIHVEALGGHLTKLTKEQAEYLGVDVEGPYKPDHYRY 495 +Y+N+VYRLPK LDEKVARIHVEALGG LT+LTKEQAEY+GVDV GP+KP+HYRY Sbjct 422 EGQYENQVYRLPKILDEKVARIHVEALGGKLTELTKEQAEYIGVDVAGPFKPEHYRY 478 >gi|38233299|ref|NP_939066.1| S-adenosyl-L-homocysteine hydrolase [Corynebacterium diphtheriae NCTC 13129] gi|47606077|sp|P61456.1|SAHH_CORDI RecName: Full=Adenosylhomocysteinase; AltName: Full=S-adenosyl-L-homocysteine hydrolase; Short=AdoHcyase gi|38199558|emb|CAE49209.1| adenosylhomocysteinase [Corynebacterium diphtheriae] Length=478 Score = 719 bits (1857), Expect = 0.0, Method: Compositional matrix adjust. Identities = 351/478 (74%), Positives = 400/478 (84%), Gaps = 4/478 (0%) Query 19 IDFKIADLSLADFGRKELRIAEHEMPGLMSLRREYAEVQPLKGARISGSLHMTVQTAVLI 78 D+ + DLSLA+ GR ++R+AE+EMPGLM LR EY + QPL GARI+GS+HMTVQTAVLI Sbjct 4 FDYNVKDLSLAEAGRHQIRLAEYEMPGLMQLREEYQQEQPLAGARITGSIHMTVQTAVLI 63 Query 79 ETLTALGAEVRWASCNIFSTQDHAAAAVVVGPHGTPDEPKGVPVFAWKGETLEEYWWAAE 138 ETL ALGA+VRWASCNIFSTQD AAAAVVVGPHGTP++P+GVPVFAWKGETLEEYW + Sbjct 64 ETLVALGAQVRWASCNIFSTQDEAAAAVVVGPHGTPEDPQGVPVFAWKGETLEEYWDCVD 123 Query 139 QMLTWPDPDKPANMILDDGGDATMLVLRGMQYEKAGVVPPAEEDDPAEWKVFLNLLRTRF 198 ++ +W D + NMILDDGGDATM V+RG Q+E+AG+VPP EE D E++ FL +LR Sbjct 124 KIFSWGD--ELPNMILDDGGDATMAVIRGKQFEEAGMVPPVEEGDSDEYQAFLGMLRKTL 181 Query 199 ETDKDKWTKIAESVKGVTEETTTGVLRLYQFAAAGDLAFPAINVNDSVTKSKFDNKYGTR 258 KWT IAESVKGVTEETTTGV RLY FA G L FPA+NVND+VTKSKFDNKYGTR Sbjct 182 AEQPGKWTAIAESVKGVTEETTTGVHRLYHFAEEGVLPFPAMNVNDAVTKSKFDNKYGTR 241 Query 259 HSLIDGINRGTDALIGGKKVLICGYGDVGKGCAEAMKGQGARVSVTEIDPINALQAMMEG 318 HSLIDGINR TD L+GGK VLICGYGDVGKGCAEAM GQGARV VTE DPINALQA+M+G Sbjct 242 HSLIDGINRATDMLMGGKNVLICGYGDVGKGCAEAMAGQGARVKVTEADPINALQALMDG 301 Query 319 FDVVTVEEAIGDADIVVTATGNKDIIMLEHIKAMKDHAILGNIGHFDNEIDMAG-LERSG 377 F VV V++AIGDADIV+TATGN II E + AMKDHA+LGNIGHFDNEIDMA L R Sbjct 302 FPVVHVDQAIGDADIVITATGNMGIISFEQMLAMKDHAVLGNIGHFDNEIDMASLLHRDD 361 Query 378 ATRVNVKPQVDLWTFGDTGRSIIVLSEGRLLNLGNATGHPSFVMSNSFANQTIAQIELWT 437 +RV +KPQVD +T + G+SI+VLSEGRLLNLGNATGHPSFVMS SFA+QTIAQIEL+ Sbjct 362 VSRVTIKPQVDEFTLPN-GKSIVVLSEGRLLNLGNATGHPSFVMSTSFADQTIAQIELFQ 420 Query 438 KNDEYDNEVYRLPKHLDEKVARIHVEALGGHLTKLTKEQAEYLGVDVEGPYKPDHYRY 495 + Y NEVYRLPK LDEKVARIHVEALGG +T+LTKEQAEY+GVDV GPYKP+HYRY Sbjct 421 NDGRYVNEVYRLPKILDEKVARIHVEALGGTITELTKEQAEYIGVDVAGPYKPEHYRY 478 >gi|68536725|ref|YP_251430.1| S-adenosyl-L-homocysteine hydrolase [Corynebacterium jeikeium K411] gi|260577915|ref|ZP_05845845.1| adenosylhomocysteinase [Corynebacterium jeikeium ATCC 43734] gi|68264324|emb|CAI37812.1| adenosylhomocysteinase [Corynebacterium jeikeium K411] gi|258603935|gb|EEW17182.1| adenosylhomocysteinase [Corynebacterium jeikeium ATCC 43734] Length=479 Score = 719 bits (1857), Expect = 0.0, Method: Compositional matrix adjust. Identities = 352/481 (74%), Positives = 406/481 (85%), Gaps = 6/481 (1%) Query 19 IDFKIADLSLADFGRKELRIAEHEMPGLMSLRREYAEVQPLKGARISGSLHMTVQTAVLI 78 ++FK+ DLSLA+ GR ++R+AE+EMPGLM LR EYAE QPLKGARI+GS+HMTVQTAVLI Sbjct 1 MEFKVKDLSLAEAGRHQIRLAEYEMPGLMQLRSEYAEEQPLKGARIAGSIHMTVQTAVLI 60 Query 79 ETLTALGAEVRWASCNIFSTQDHAAAAVVVGPHGTPDEPKGVPVFAWKGETLEEYWWAAE 138 ETL ALGAEVRWASCNIFSTQD AAAA+VVG GTP+ P GVPVFAWKGETL+EYWW + Sbjct 61 ETLVALGAEVRWASCNIFSTQDEAAAAIVVG-DGTPESPAGVPVFAWKGETLDEYWWCLK 119 Query 139 QMLTWPDPDKPANMILDDGGDATMLVLRGMQYEKAGVVPPAEEDDPAEWKVFLNLLRTRF 198 Q+ TW + + ANMILDDGGDATM V++GM+YE AG+VP AEE D E+K FL +LR Sbjct 120 QIFTWGEGVE-ANMILDDGGDATMAVIKGMEYENAGLVPDAEEQDADEYKAFLGMLRETL 178 Query 199 ETDKDKWTKIAESVKGVTEETTTGVLRLYQFAAAGDLAFPAINVNDSVTKSKFDNKYGTR 258 D W++ +E++KGVTEETTTGV RLY FA G L FPA+NVND+VTKSKFDN+YGTR Sbjct 179 AEDGKFWSRASENIKGVTEETTTGVHRLYHFAEQGLLPFPAMNVNDAVTKSKFDNRYGTR 238 Query 259 HSLIDGINRGTDALIGGKKVLICGYGDVGKGCAEAMKGQGARVSVTEIDPINALQAMMEG 318 HSLIDGINR TD LIGGK VL+CGYGDVGKGCAEA+ GQGA V VTE+DPINALQA+M+G Sbjct 239 HSLIDGINRATDMLIGGKSVLLCGYGDVGKGCAEALAGQGAIVKVTEVDPINALQALMDG 298 Query 319 FDVVTVEEAIGDADIVVTATGNKDIIMLEHIKAMKDHAILGNIGHFDNEIDMAG-LERSG 377 F+VV VE+ IGDADIV+TATGN II EH++ MK+HA+LGNIGHFDNEIDMA L R Sbjct 299 FEVVQVEDFIGDADIVITATGNLGIITFEHMQMMKNHAVLGNIGHFDNEIDMASLLHRED 358 Query 378 ATRVNVKPQVDLWTF-GDTGR--SIIVLSEGRLLNLGNATGHPSFVMSNSFANQTIAQIE 434 +RV +KPQVD +TF G G SI+VLSEGRLLNLGNATGHPSFVMSNSFA+QTIAQIE Sbjct 359 VSRVTIKPQVDEFTFEGKNGDPVSIVVLSEGRLLNLGNATGHPSFVMSNSFADQTIAQIE 418 Query 435 LWTKNDEYDNEVYRLPKHLDEKVARIHVEALGGHLTKLTKEQAEYLGVDVEGPYKPDHYR 494 L+TK+D+Y NEVYRLPK LDE VARIHVEALGG LT LTKEQAEY+GVDV GP+KP+HYR Sbjct 419 LYTKSDQYGNEVYRLPKILDEMVARIHVEALGGKLTTLTKEQAEYIGVDVAGPFKPEHYR 478 Query 495 Y 495 Y Sbjct 479 Y 479 Lambda K H 0.316 0.135 0.400 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 1062409466196 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40