BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv3255c Length=408 Score E Sequences producing significant alignments: (Bits) Value gi|15610391|ref|NP_217772.1| mannose-6-phosphate isomerase [Myco... 806 0.0 gi|289575974|ref|ZP_06456201.1| mannose-6-phosphate isomerase ma... 804 0.0 gi|118618070|ref|YP_906402.1| mannose-6-phosphate isomerase ManA... 718 0.0 gi|183981309|ref|YP_001849600.1| mannose-6-phosphate isomerase M... 716 0.0 gi|240172601|ref|ZP_04751260.1| mannose-6-phosphate isomerase Ma... 703 0.0 gi|296168950|ref|ZP_06850619.1| mannose-6-phosphate isomerase [M... 699 0.0 gi|342861458|ref|ZP_08718105.1| mannose-6-phosphate isomerase [M... 696 0.0 gi|254823002|ref|ZP_05228003.1| mannose-6-phosphate isomerase, c... 696 0.0 gi|41409465|ref|NP_962301.1| hypothetical protein MAP3367c [Myco... 686 0.0 gi|15827331|ref|NP_301594.1| mannose-6-phosphate isomerase [Myco... 686 0.0 gi|254776654|ref|ZP_05218170.1| mannose-6-phosphate isomerase, c... 685 0.0 gi|333991644|ref|YP_004524258.1| mannose-6-phosphate isomerase M... 640 0.0 gi|22023937|gb|AAM89255.1|AF527174_1 phosphomannose isomerase [M... 630 1e-178 gi|120402739|ref|YP_952568.1| mannose-6-phosphate isomerase, cla... 602 4e-170 gi|145225302|ref|YP_001135980.1| mannose-6-phosphate isomerase, ... 602 5e-170 gi|315445600|ref|YP_004078479.1| mannose-6-phosphate isomerase, ... 600 1e-169 gi|126433968|ref|YP_001069659.1| mannose-6-phosphate isomerase [... 600 2e-169 gi|108798301|ref|YP_638498.1| mannose-6-phosphate isomerase [Myc... 598 4e-169 gi|118468938|ref|YP_886206.1| mannose-6-phosphate isomerase, cla... 583 2e-164 gi|169630681|ref|YP_001704330.1| mannose-6-phosphate isomerase M... 502 4e-140 gi|289571482|ref|ZP_06451709.1| mannose-6-phosphate isomerase ma... 463 2e-128 gi|296138916|ref|YP_003646159.1| mannose-6-phosphate isomerase, ... 446 5e-123 gi|325675686|ref|ZP_08155370.1| mannose-6-phosphate isomerase [R... 444 9e-123 gi|54026600|ref|YP_120842.1| putative mannose-6-phosphate isomer... 442 6e-122 gi|226365789|ref|YP_002783572.1| mannose-6-phosphate isomerase [... 440 2e-121 gi|229489355|ref|ZP_04383218.1| mannose-6-phosphate isomerase, c... 439 3e-121 gi|111023281|ref|YP_706253.1| mannose-6-phosphate isomerase [Rho... 438 9e-121 gi|226305646|ref|YP_002765606.1| mannose-6-phosphate isomerase [... 436 5e-120 gi|256380312|ref|YP_003103972.1| mannose-6-phosphate isomerase, ... 424 2e-116 gi|343926913|ref|ZP_08766406.1| mannose-6-phosphate isomerase [G... 417 1e-114 gi|262203186|ref|YP_003274394.1| mannose-6-phosphate isomerase, ... 413 3e-113 gi|257057069|ref|YP_003134901.1| mannose-6-phosphate isomerase [... 399 5e-109 gi|291008025|ref|ZP_06565998.1| mannose-6-phosphate isomerase [S... 397 2e-108 gi|111022402|ref|YP_705374.1| mannose-6-phosphate isomerase [Rho... 397 3e-108 gi|302530040|ref|ZP_07282382.1| mannose-6-phosphate isomerase, c... 390 2e-106 gi|325000904|ref|ZP_08122016.1| mannose-6-phosphate isomerase Ma... 390 3e-106 gi|300789827|ref|YP_003770118.1| mannose-6-phosphate isomerase [... 388 7e-106 gi|134102890|ref|YP_001108551.1| mannose-6-phosphate isomerase [... 388 9e-106 gi|331698949|ref|YP_004335188.1| mannose-6-phosphate isomerase, ... 384 2e-104 gi|326381473|ref|ZP_08203167.1| mannose-6-phosphate isomerase [G... 379 5e-103 gi|312140684|ref|YP_004008020.1| mannose-6-phosphate isomerase m... 373 3e-101 gi|258654287|ref|YP_003203443.1| mannose-6-phosphate isomerase, ... 363 4e-98 gi|344043751|gb|EGV39439.1| mannose-6-phosphate isomerase [Coryn... 352 7e-95 gi|145294910|ref|YP_001137731.1| hypothetical protein cgR_0857 [... 352 9e-95 gi|19551976|ref|NP_599978.1| phosphomannose isomerase [Corynebac... 351 1e-94 gi|306835483|ref|ZP_07468500.1| mannose-6-phosphate isomerase [C... 350 3e-94 gi|227502884|ref|ZP_03932933.1| possible mannose-6-phosphate iso... 347 2e-93 gi|300857929|ref|YP_003782912.1| mannose-6-phosphate isomerase [... 345 7e-93 gi|25027320|ref|NP_737374.1| putative mannose-6-phosphate isomer... 344 1e-92 gi|296118800|ref|ZP_06837376.1| mannose-6-phosphate isomerase, c... 342 5e-92 >gi|15610391|ref|NP_217772.1| mannose-6-phosphate isomerase [Mycobacterium tuberculosis H37Rv] gi|15842844|ref|NP_337881.1| mannose-6-phosphate isomerase [Mycobacterium tuberculosis CDC1551] gi|31794435|ref|NP_856928.1| mannose-6-phosphate isomerase [Mycobacterium bovis AF2122/97] 72 more sequence titles Length=408 Score = 806 bits (2082), Expect = 0.0, Method: Compositional matrix adjust. Identities = 407/408 (99%), Positives = 408/408 (100%), Gaps = 0/408 (0%) Query 1 VELLRGALRTYAWGSRTAIAEFTGRPVPAAHPEAELWFGAHPGDPAWLQTPHGQTSLLEA 60 +ELLRGALRTYAWGSRTAIAEFTGRPVPAAHPEAELWFGAHPGDPAWLQTPHGQTSLLEA Sbjct 1 MELLRGALRTYAWGSRTAIAEFTGRPVPAAHPEAELWFGAHPGDPAWLQTPHGQTSLLEA 60 Query 61 LVADPEGQLGSASRARFGDVLPFLVKVLAADEPLSLQAHPSAEQAVEGYLREERMGIPVS 120 LVADPEGQLGSASRARFGDVLPFLVKVLAADEPLSLQAHPSAEQAVEGYLREERMGIPVS Sbjct 61 LVADPEGQLGSASRARFGDVLPFLVKVLAADEPLSLQAHPSAEQAVEGYLREERMGIPVS 120 Query 121 SPVRNYRDTSHKPELLVALQPFEALAGFREAARTTELLRALAVSDLDPFIDLLSEGSDAD 180 SPVRNYRDTSHKPELLVALQPFEALAGFREAARTTELLRALAVSDLDPFIDLLSEGSDAD Sbjct 121 SPVRNYRDTSHKPELLVALQPFEALAGFREAARTTELLRALAVSDLDPFIDLLSEGSDAD 180 Query 181 GLRALFTTWITAPQPDIDVLVPAVLDGAIQYVSSGATEFGAEAKTVLELGERYPGDAGVL 240 GLRALFTTWITAPQPDIDVLVPAVLDGAIQYVSSGATEFGAEAKTVLELGERYPGDAGVL Sbjct 181 GLRALFTTWITAPQPDIDVLVPAVLDGAIQYVSSGATEFGAEAKTVLELGERYPGDAGVL 240 Query 241 AALLLNRISLAPGEAIFLPAGNLHAYVRGFGVEVMANSDNVLRGGLTPKHVDVPELLRVL 300 AALLLNRISLAPGEAIFLPAGNLHAYVRGFGVEVMANSDNVLRGGLTPKHVDVPELLRVL Sbjct 241 AALLLNRISLAPGEAIFLPAGNLHAYVRGFGVEVMANSDNVLRGGLTPKHVDVPELLRVL 300 Query 301 DFAPTPKARLRPPIRREGLGLVFETPTDEFAATLLVLDGDHLGHEVDASSGHDGPQILLC 360 DFAPTPKARLRPPIRREGLGLVFETPTDEFAATLLVLDGDHLGHEVDASSGHDGPQILLC Sbjct 301 DFAPTPKARLRPPIRREGLGLVFETPTDEFAATLLVLDGDHLGHEVDASSGHDGPQILLC 360 Query 361 TEGSATVHGKCGSLTLQRGTAAWVAADDGPIRLTAGQPAKLFRATVGL 408 TEGSATVHGKCGSLTLQRGTAAWVAADDGPIRLTAGQPAKLFRATVGL Sbjct 361 TEGSATVHGKCGSLTLQRGTAAWVAADDGPIRLTAGQPAKLFRATVGL 408 >gi|289575974|ref|ZP_06456201.1| mannose-6-phosphate isomerase manA [Mycobacterium tuberculosis K85] gi|339633265|ref|YP_004724907.1| mannose-6-phosphate isomerase MANA (phosphomannose isomerase) [Mycobacterium africanum GM041182] gi|289540405|gb|EFD44983.1| mannose-6-phosphate isomerase manA [Mycobacterium tuberculosis K85] gi|339332621|emb|CCC28336.1| putative mannose-6-phosphate isomerase MANA (phosphomannose isomerase) [Mycobacterium africanum GM041182] Length=408 Score = 804 bits (2077), Expect = 0.0, Method: Compositional matrix adjust. Identities = 406/408 (99%), Positives = 407/408 (99%), Gaps = 0/408 (0%) Query 1 VELLRGALRTYAWGSRTAIAEFTGRPVPAAHPEAELWFGAHPGDPAWLQTPHGQTSLLEA 60 +ELLRGALRTYAWGSRTAIAEFTGRPVPAAHPEAELWFGAHPGDPAWLQTPHGQTSLLEA Sbjct 1 MELLRGALRTYAWGSRTAIAEFTGRPVPAAHPEAELWFGAHPGDPAWLQTPHGQTSLLEA 60 Query 61 LVADPEGQLGSASRARFGDVLPFLVKVLAADEPLSLQAHPSAEQAVEGYLREERMGIPVS 120 LVADPEGQLGSASRARFGDVLPFLVKVLAADEPLSLQAHPSAEQAVEGYLREERMGIPVS Sbjct 61 LVADPEGQLGSASRARFGDVLPFLVKVLAADEPLSLQAHPSAEQAVEGYLREERMGIPVS 120 Query 121 SPVRNYRDTSHKPELLVALQPFEALAGFREAARTTELLRALAVSDLDPFIDLLSEGSDAD 180 SPVRNYRDTSHKPELLVALQPFEALAGFREAARTTELLRALAVSDLDPFIDLLSEGSDAD Sbjct 121 SPVRNYRDTSHKPELLVALQPFEALAGFREAARTTELLRALAVSDLDPFIDLLSEGSDAD 180 Query 181 GLRALFTTWITAPQPDIDVLVPAVLDGAIQYVSSGATEFGAEAKTVLELGERYPGDAGVL 240 GLRALFTTWITAPQPDIDVLVPAVLDGAIQYVSSGATEFGAEAKTVLELGERYPGDAGVL Sbjct 181 GLRALFTTWITAPQPDIDVLVPAVLDGAIQYVSSGATEFGAEAKTVLELGERYPGDAGVL 240 Query 241 AALLLNRISLAPGEAIFLPAGNLHAYVRGFGVEVMANSDNVLRGGLTPKHVDVPELLRVL 300 AALLLNRISLAPGEAIFLPAGNLHAYVRGFGVEVMANSDNVLRGGLTPKHVDVPELLRVL Sbjct 241 AALLLNRISLAPGEAIFLPAGNLHAYVRGFGVEVMANSDNVLRGGLTPKHVDVPELLRVL 300 Query 301 DFAPTPKARLRPPIRREGLGLVFETPTDEFAATLLVLDGDHLGHEVDASSGHDGPQILLC 360 DFAPTPKARLRPPIRREGLGLVFETPTDEFAATLLVLDGDHLGHEVDASSGHDGPQILLC Sbjct 301 DFAPTPKARLRPPIRREGLGLVFETPTDEFAATLLVLDGDHLGHEVDASSGHDGPQILLC 360 Query 361 TEGSATVHGKCGSLTLQRGTAAWVAADDGPIRLTAGQPAKLFRATVGL 408 TEGSATVHGKCGSLTLQRGTAAW AADDGPIRLTAGQPAKLFRATVGL Sbjct 361 TEGSATVHGKCGSLTLQRGTAAWAAADDGPIRLTAGQPAKLFRATVGL 408 >gi|118618070|ref|YP_906402.1| mannose-6-phosphate isomerase ManA [Mycobacterium ulcerans Agy99] gi|118570180|gb|ABL04931.1| mannose-6-phosphate isomerase ManA [Mycobacterium ulcerans Agy99] Length=408 Score = 718 bits (1854), Expect = 0.0, Method: Compositional matrix adjust. Identities = 362/408 (89%), Positives = 380/408 (94%), Gaps = 0/408 (0%) Query 1 VELLRGALRTYAWGSRTAIAEFTGRPVPAAHPEAELWFGAHPGDPAWLQTPHGQTSLLEA 60 +ELLRGALRTYAWGSRTAIAEFTGRPVPAAHPEAELWFGAHPGDPAWL+T G++SLLE Sbjct 1 MELLRGALRTYAWGSRTAIAEFTGRPVPAAHPEAELWFGAHPGDPAWLETDGGESSLLET 60 Query 61 LVADPEGQLGSASRARFGDVLPFLVKVLAADEPLSLQAHPSAEQAVEGYLREERMGIPVS 120 L ADPEGQLG +RARFGDVLPFLVKVLAADEPLSLQAHPSAEQAVEGYLREERMGIPVS Sbjct 61 LSADPEGQLGPGARARFGDVLPFLVKVLAADEPLSLQAHPSAEQAVEGYLREERMGIPVS 120 Query 121 SPVRNYRDTSHKPELLVALQPFEALAGFREAARTTELLRALAVSDLDPFIDLLSEGSDAD 180 SPVRNYRDTSHKPELLVALQPFEALAGFR+AART ELL+ALAVSDLDPFIDLL + SDAD Sbjct 121 SPVRNYRDTSHKPELLVALQPFEALAGFRQAARTRELLQALAVSDLDPFIDLLFDQSDAD 180 Query 181 GLRALFTTWITAPQPDIDVLVPAVLDGAIQYVSSGATEFGAEAKTVLELGERYPGDAGVL 240 GLRALFTTWITAPQPDIDVLVPAVLDGAIQYVSSGATEF AEAKTVLELGERYPGDAGVL Sbjct 181 GLRALFTTWITAPQPDIDVLVPAVLDGAIQYVSSGATEFVAEAKTVLELGERYPGDAGVL 240 Query 241 AALLLNRISLAPGEAIFLPAGNLHAYVRGFGVEVMANSDNVLRGGLTPKHVDVPELLRVL 300 AALLLNRISLAPGEAIFLPAGNLHAY+RGF +EVMANSDNVLRGGLTPKHVDVPELLRVL Sbjct 241 AALLLNRISLAPGEAIFLPAGNLHAYLRGFALEVMANSDNVLRGGLTPKHVDVPELLRVL 300 Query 301 DFAPTPKARLRPPIRREGLGLVFETPTDEFAATLLVLDGDHLGHEVDASSGHDGPQILLC 360 DFAPT + LRPP+RREG LV+ETPTDEFA LLVLDGD+LGHE+DASS H+GPQILLC Sbjct 301 DFAPTAASDLRPPVRREGPELVYETPTDEFAVALLVLDGDYLGHEIDASSSHEGPQILLC 360 Query 361 TEGSATVHGKCGSLTLQRGTAAWVAADDGPIRLTAGQPAKLFRATVGL 408 TEGS VHGK SLTL+ G AAWVAADDGPIRL A +P KLFRATVGL Sbjct 361 TEGSTVVHGKSQSLTLEHGNAAWVAADDGPIRLLAQEPTKLFRATVGL 408 >gi|183981309|ref|YP_001849600.1| mannose-6-phosphate isomerase ManA [Mycobacterium marinum M] gi|183174635|gb|ACC39745.1| mannose-6-phosphate isomerase ManA [Mycobacterium marinum M] Length=408 Score = 716 bits (1849), Expect = 0.0, Method: Compositional matrix adjust. Identities = 361/408 (89%), Positives = 379/408 (93%), Gaps = 0/408 (0%) Query 1 VELLRGALRTYAWGSRTAIAEFTGRPVPAAHPEAELWFGAHPGDPAWLQTPHGQTSLLEA 60 +ELLRGALRTYAWGSRTAIAEFTGRPVPAAHPEAELWFGAHPGDPAWL+T G++SLLE Sbjct 1 MELLRGALRTYAWGSRTAIAEFTGRPVPAAHPEAELWFGAHPGDPAWLETDGGESSLLET 60 Query 61 LVADPEGQLGSASRARFGDVLPFLVKVLAADEPLSLQAHPSAEQAVEGYLREERMGIPVS 120 L ADPEGQLG +RARFGDVLPFLVKVLAADEPLSLQAHPSAEQAVEGYLREERMGIPVS Sbjct 61 LSADPEGQLGPGARARFGDVLPFLVKVLAADEPLSLQAHPSAEQAVEGYLREERMGIPVS 120 Query 121 SPVRNYRDTSHKPELLVALQPFEALAGFREAARTTELLRALAVSDLDPFIDLLSEGSDAD 180 SPVRNYRDTSHKPELLVALQPFEALAGFR+AART ELL+ALAVSDLDPFIDLL + SDAD Sbjct 121 SPVRNYRDTSHKPELLVALQPFEALAGFRQAARTRELLQALAVSDLDPFIDLLFDQSDAD 180 Query 181 GLRALFTTWITAPQPDIDVLVPAVLDGAIQYVSSGATEFGAEAKTVLELGERYPGDAGVL 240 GLRALFTTWITAPQPDIDVLVPAVLDGAI YVSSGATEF AEAKTVLELGERYPGDAGVL Sbjct 181 GLRALFTTWITAPQPDIDVLVPAVLDGAIHYVSSGATEFVAEAKTVLELGERYPGDAGVL 240 Query 241 AALLLNRISLAPGEAIFLPAGNLHAYVRGFGVEVMANSDNVLRGGLTPKHVDVPELLRVL 300 AALLLNRISLAPGEAIFLPAGNLHAY+RGF +EVMANSDNVLRGGLTPKHVDVPELLRVL Sbjct 241 AALLLNRISLAPGEAIFLPAGNLHAYLRGFALEVMANSDNVLRGGLTPKHVDVPELLRVL 300 Query 301 DFAPTPKARLRPPIRREGLGLVFETPTDEFAATLLVLDGDHLGHEVDASSGHDGPQILLC 360 DFAPT + LRPP+RREG LV+ETPTDEFA LLVLDGD+LGHE+DASS H+GPQILLC Sbjct 301 DFAPTAASDLRPPVRREGPELVYETPTDEFAVALLVLDGDYLGHEIDASSSHEGPQILLC 360 Query 361 TEGSATVHGKCGSLTLQRGTAAWVAADDGPIRLTAGQPAKLFRATVGL 408 TEGS VHGK SLTL+ G AAWVAADDGPIRL A +P KLFRATVGL Sbjct 361 TEGSTVVHGKSQSLTLEHGNAAWVAADDGPIRLLAQEPTKLFRATVGL 408 >gi|240172601|ref|ZP_04751260.1| mannose-6-phosphate isomerase ManA [Mycobacterium kansasii ATCC 12478] Length=408 Score = 703 bits (1814), Expect = 0.0, Method: Compositional matrix adjust. Identities = 350/408 (86%), Positives = 376/408 (93%), Gaps = 0/408 (0%) Query 1 VELLRGALRTYAWGSRTAIAEFTGRPVPAAHPEAELWFGAHPGDPAWLQTPHGQTSLLEA 60 +ELLRGALRTYAWGSRTAIAEFTGRPVPAAHPEAELWFGAHPGDPAWL+T +G+TSLLEA Sbjct 1 MELLRGALRTYAWGSRTAIAEFTGRPVPAAHPEAELWFGAHPGDPAWLETDNGETSLLEA 60 Query 61 LVADPEGQLGSASRARFGDVLPFLVKVLAADEPLSLQAHPSAEQAVEGYLREERMGIPVS 120 L ADPEGQLG SR RFGDVLPFLVKVLAADEPLSLQAHPSAEQA+EGYLREER+GIPV+ Sbjct 61 LSADPEGQLGHGSRTRFGDVLPFLVKVLAADEPLSLQAHPSAEQAIEGYLREERLGIPVA 120 Query 121 SPVRNYRDTSHKPELLVALQPFEALAGFREAARTTELLRALAVSDLDPFIDLLSEGSDAD 180 SPVRNYRDTSHKPELLVALQPFEALAGFR+AART ELL+ALAVSDLDPFIDLLS+ SDAD Sbjct 121 SPVRNYRDTSHKPELLVALQPFEALAGFRQAARTRELLQALAVSDLDPFIDLLSDQSDAD 180 Query 181 GLRALFTTWITAPQPDIDVLVPAVLDGAIQYVSSGATEFGAEAKTVLELGERYPGDAGVL 240 GLRALFTTWITAPQPDIDVLVPAVL+GAI YVSSGATEF AE KTVLELGERYPGDAGVL Sbjct 181 GLRALFTTWITAPQPDIDVLVPAVLEGAIHYVSSGATEFAAEVKTVLELGERYPGDAGVL 240 Query 241 AALLLNRISLAPGEAIFLPAGNLHAYVRGFGVEVMANSDNVLRGGLTPKHVDVPELLRVL 300 AALLLNRISL+PGEAIFLPAGNLH Y+RGF +EVMANSDNVLRGGLTPKHVDVPELLRVL Sbjct 241 AALLLNRISLSPGEAIFLPAGNLHTYLRGFALEVMANSDNVLRGGLTPKHVDVPELLRVL 300 Query 301 DFAPTPKARLRPPIRREGLGLVFETPTDEFAATLLVLDGDHLGHEVDASSGHDGPQILLC 360 DFAPT ++ LRPPIRR+GL LV++TP +EFA LL L D LGHE+DA S H+GPQILLC Sbjct 301 DFAPTAESALRPPIRRDGLELVYDTPAEEFAVALLALGADQLGHEIDAPSSHEGPQILLC 360 Query 361 TEGSATVHGKCGSLTLQRGTAAWVAADDGPIRLTAGQPAKLFRATVGL 408 TEGS VHGK SLTL++G AAWVAA+DGPIRL A +P KLFRATVGL Sbjct 361 TEGSTMVHGKSKSLTLKQGMAAWVAAEDGPIRLLAHEPTKLFRATVGL 408 >gi|296168950|ref|ZP_06850619.1| mannose-6-phosphate isomerase [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295896419|gb|EFG76072.1| mannose-6-phosphate isomerase [Mycobacterium parascrofulaceum ATCC BAA-614] Length=408 Score = 699 bits (1805), Expect = 0.0, Method: Compositional matrix adjust. Identities = 346/408 (85%), Positives = 374/408 (92%), Gaps = 0/408 (0%) Query 1 VELLRGALRTYAWGSRTAIAEFTGRPVPAAHPEAELWFGAHPGDPAWLQTPHGQTSLLEA 60 +ELLRGALRTYAWGSRTAIAEFTGRPVPAAHPEAELWFGAHPGDPAWL+T G+ SLL+A Sbjct 1 MELLRGALRTYAWGSRTAIAEFTGRPVPAAHPEAELWFGAHPGDPAWLETGTGEVSLLDA 60 Query 61 LVADPEGQLGSASRARFGDVLPFLVKVLAADEPLSLQAHPSAEQAVEGYLREERMGIPVS 120 LVADPEGQLG +RARFGDVLPFLVKVLAADEPLSLQAHPSA QA EGYLREER+GIP+S Sbjct 61 LVADPEGQLGPGARARFGDVLPFLVKVLAADEPLSLQAHPSAAQAAEGYLREERLGIPLS 120 Query 121 SPVRNYRDTSHKPELLVALQPFEALAGFREAARTTELLRALAVSDLDPFIDLLSEGSDAD 180 SPVRNYRDTSHKPELLVALQPFEALAGFR+A+RT ELLRALAVSDLDP+I+LL++ SDAD Sbjct 121 SPVRNYRDTSHKPELLVALQPFEALAGFRQASRTVELLRALAVSDLDPYIELLNDQSDAD 180 Query 181 GLRALFTTWITAPQPDIDVLVPAVLDGAIQYVSSGATEFGAEAKTVLELGERYPGDAGVL 240 GLRALFTTWITAPQPDID LVPAVLDGAI+Y+SSGATEF EAKTVLELGERYPGDAGVL Sbjct 181 GLRALFTTWITAPQPDIDALVPAVLDGAIEYISSGATEFAGEAKTVLELGERYPGDAGVL 240 Query 241 AALLLNRISLAPGEAIFLPAGNLHAYVRGFGVEVMANSDNVLRGGLTPKHVDVPELLRVL 300 AALLLNRI LAPGEAIF+ AG+LH Y+RGF VEVMANSDNVLRGGLTPKHVDVPELLRVL Sbjct 241 AALLLNRIMLAPGEAIFVSAGSLHTYLRGFAVEVMANSDNVLRGGLTPKHVDVPELLRVL 300 Query 301 DFAPTPKARLRPPIRREGLGLVFETPTDEFAATLLVLDGDHLGHEVDASSGHDGPQILLC 360 DF PT +A++RP +RREG GL++ETP DEFA LL LDGD+LGHEVDAS H+GPQILLC Sbjct 301 DFTPTTEAQVRPAVRREGFGLIYETPADEFAVALLELDGDYLGHEVDASCSHEGPQILLC 360 Query 361 TEGSATVHGKCGSLTLQRGTAAWVAADDGPIRLTAGQPAKLFRATVGL 408 TEG TVHGK GSLTL+RG AAWVAADD PIRL A +P KLFRATVGL Sbjct 361 TEGCTTVHGKSGSLTLRRGMAAWVAADDTPIRLVAREPTKLFRATVGL 408 >gi|342861458|ref|ZP_08718105.1| mannose-6-phosphate isomerase [Mycobacterium colombiense CECT 3035] gi|342130947|gb|EGT84236.1| mannose-6-phosphate isomerase [Mycobacterium colombiense CECT 3035] Length=408 Score = 696 bits (1796), Expect = 0.0, Method: Compositional matrix adjust. Identities = 345/408 (85%), Positives = 373/408 (92%), Gaps = 0/408 (0%) Query 1 VELLRGALRTYAWGSRTAIAEFTGRPVPAAHPEAELWFGAHPGDPAWLQTPHGQTSLLEA 60 +ELLRGALRTYAWGSRTAIAEFT RPVPAAHPEAELWFGAHPGDPAWL+T +G+ +LLEA Sbjct 1 MELLRGALRTYAWGSRTAIAEFTERPVPAAHPEAELWFGAHPGDPAWLETGNGEITLLEA 60 Query 61 LVADPEGQLGSASRARFGDVLPFLVKVLAADEPLSLQAHPSAEQAVEGYLREERMGIPVS 120 L DPEGQLG ASRARFGDVLPFLVKVLAADEPLSLQAHPSA QA EGYLREER+GIP++ Sbjct 61 LGDDPEGQLGQASRARFGDVLPFLVKVLAADEPLSLQAHPSAAQAAEGYLREERVGIPLN 120 Query 121 SPVRNYRDTSHKPELLVALQPFEALAGFREAARTTELLRALAVSDLDPFIDLLSEGSDAD 180 SPVRNYRD SHKPELLVAL PFEALAGFR+A+RT ELLRALAVSDLDP+IDLL++ SDAD Sbjct 121 SPVRNYRDMSHKPELLVALHPFEALAGFRQASRTVELLRALAVSDLDPYIDLLNDQSDAD 180 Query 181 GLRALFTTWITAPQPDIDVLVPAVLDGAIQYVSSGATEFGAEAKTVLELGERYPGDAGVL 240 GLRALFTTWITAPQPDIDVLV AVLDGAI YVSSGATEF AEAKTVLELGERYPGDAGVL Sbjct 181 GLRALFTTWITAPQPDIDVLVTAVLDGAIAYVSSGATEFAAEAKTVLELGERYPGDAGVL 240 Query 241 AALLLNRISLAPGEAIFLPAGNLHAYVRGFGVEVMANSDNVLRGGLTPKHVDVPELLRVL 300 AALLLNR+SLAPGEAIF+ AGNLH Y+RGF VEVMANSDNVLRGGLTPKHVDVPELLRVL Sbjct 241 AALLLNRVSLAPGEAIFVSAGNLHTYLRGFAVEVMANSDNVLRGGLTPKHVDVPELLRVL 300 Query 301 DFAPTPKARLRPPIRREGLGLVFETPTDEFAATLLVLDGDHLGHEVDASSGHDGPQILLC 360 DFAPT + +LRPPIRREG GL++ETPTDEFA LL LD +++GHEVDA+ HDGPQILLC Sbjct 301 DFAPTTEEQLRPPIRREGFGLIYETPTDEFAVALLELDDEYVGHEVDATCSHDGPQILLC 360 Query 361 TEGSATVHGKCGSLTLQRGTAAWVAADDGPIRLTAGQPAKLFRATVGL 408 ++G TVHGK GSLTL+RG AAWVAADD PIRL A +P KLFRATVGL Sbjct 361 SQGCTTVHGKSGSLTLKRGMAAWVAADDAPIRLEAHEPTKLFRATVGL 408 >gi|254823002|ref|ZP_05228003.1| mannose-6-phosphate isomerase, class I [Mycobacterium intracellulare ATCC 13950] Length=408 Score = 696 bits (1795), Expect = 0.0, Method: Compositional matrix adjust. Identities = 345/408 (85%), Positives = 373/408 (92%), Gaps = 0/408 (0%) Query 1 VELLRGALRTYAWGSRTAIAEFTGRPVPAAHPEAELWFGAHPGDPAWLQTPHGQTSLLEA 60 +ELLRGALRTYAWGSRTAIAEFT RPVPAAHPEAELWFGAHPGDPAWL+T +G+ +LLEA Sbjct 1 MELLRGALRTYAWGSRTAIAEFTERPVPAAHPEAELWFGAHPGDPAWLETDNGEITLLEA 60 Query 61 LVADPEGQLGSASRARFGDVLPFLVKVLAADEPLSLQAHPSAEQAVEGYLREERMGIPVS 120 L ADPEGQLG SRARFGDVLPFLVKVLAADEPLSLQAHPSA QA EGYLREER+GIP++ Sbjct 61 LDADPEGQLGPGSRARFGDVLPFLVKVLAADEPLSLQAHPSAAQAAEGYLREERVGIPLT 120 Query 121 SPVRNYRDTSHKPELLVALQPFEALAGFREAARTTELLRALAVSDLDPFIDLLSEGSDAD 180 SPVRNYRDTSHKPELLVAL PFEALAGFR+ +RT ELLRALAVSDLDPFIDLL++ SDAD Sbjct 121 SPVRNYRDTSHKPELLVALHPFEALAGFRQVSRTVELLRALAVSDLDPFIDLLNDQSDAD 180 Query 181 GLRALFTTWITAPQPDIDVLVPAVLDGAIQYVSSGATEFGAEAKTVLELGERYPGDAGVL 240 GLRALFTTWITAPQPDIDVLVPAVLDGAI Y+SSGATEF AEAKTVLELGERYPGDAGVL Sbjct 181 GLRALFTTWITAPQPDIDVLVPAVLDGAIAYLSSGATEFAAEAKTVLELGERYPGDAGVL 240 Query 241 AALLLNRISLAPGEAIFLPAGNLHAYVRGFGVEVMANSDNVLRGGLTPKHVDVPELLRVL 300 AALLLNR+SL PGEAIF+ AGNLH Y+RGF VEVMANSDNVLRGGLTPKHVDVPELLRVL Sbjct 241 AALLLNRVSLGPGEAIFVSAGNLHTYLRGFAVEVMANSDNVLRGGLTPKHVDVPELLRVL 300 Query 301 DFAPTPKARLRPPIRREGLGLVFETPTDEFAATLLVLDGDHLGHEVDASSGHDGPQILLC 360 DFAPT + RLRP IRREG GL++ETPTDEFA LL L+ +++GHEVDA+ HDGPQILLC Sbjct 301 DFAPTTEERLRPHIRREGFGLIYETPTDEFAVALLDLEDEYVGHEVDATCSHDGPQILLC 360 Query 361 TEGSATVHGKCGSLTLQRGTAAWVAADDGPIRLTAGQPAKLFRATVGL 408 +GS TVHGK GSLTL+RG AAWVAADD PIRL A +P+KLFRATVGL Sbjct 361 IQGSTTVHGKSGSLTLKRGMAAWVAADDAPIRLVAHEPSKLFRATVGL 408 >gi|41409465|ref|NP_962301.1| hypothetical protein MAP3367c [Mycobacterium avium subsp. paratuberculosis K-10] gi|118467227|ref|YP_883360.1| mannose-6-phosphate isomerase, class I [Mycobacterium avium 104] gi|41398296|gb|AAS05917.1| ManA [Mycobacterium avium subsp. paratuberculosis K-10] gi|118168514|gb|ABK69411.1| mannose-6-phosphate isomerase, class I [Mycobacterium avium 104] gi|336459669|gb|EGO38604.1| mannose-6-phosphate isomerase, class I [Mycobacterium avium subsp. paratuberculosis S397] Length=408 Score = 686 bits (1770), Expect = 0.0, Method: Compositional matrix adjust. Identities = 341/408 (84%), Positives = 370/408 (91%), Gaps = 0/408 (0%) Query 1 VELLRGALRTYAWGSRTAIAEFTGRPVPAAHPEAELWFGAHPGDPAWLQTPHGQTSLLEA 60 +ELLRGALRTYAWGSRTAIAEFT RPVPAAHPEAELWFGAHPGDPAWL+T +G+ +LL+A Sbjct 1 MELLRGALRTYAWGSRTAIAEFTERPVPAAHPEAELWFGAHPGDPAWLETDNGEITLLDA 60 Query 61 LVADPEGQLGSASRARFGDVLPFLVKVLAADEPLSLQAHPSAEQAVEGYLREERMGIPVS 120 L ADPEGQLG SRARFGDVLPFLVKVLAADEPLSLQAHPSAEQA EGYLREER+GIP++ Sbjct 61 LRADPEGQLGPGSRARFGDVLPFLVKVLAADEPLSLQAHPSAEQAAEGYLREERLGIPLN 120 Query 121 SPVRNYRDTSHKPELLVALQPFEALAGFREAARTTELLRALAVSDLDPFIDLLSEGSDAD 180 SPVRNYRDTSHKPELLVAL PFEALAGFR A+RT ELLRALAVSDLDPFI+LL + SDAD Sbjct 121 SPVRNYRDTSHKPELLVALYPFEALAGFRPASRTVELLRALAVSDLDPFIELLGDQSDAD 180 Query 181 GLRALFTTWITAPQPDIDVLVPAVLDGAIQYVSSGATEFGAEAKTVLELGERYPGDAGVL 240 GLRALFTTWITAPQPDIDVLVPAVLDGAI Y+SSGATEF AEAKTVLELGERYPGDAGVL Sbjct 181 GLRALFTTWITAPQPDIDVLVPAVLDGAIAYLSSGATEFAAEAKTVLELGERYPGDAGVL 240 Query 241 AALLLNRISLAPGEAIFLPAGNLHAYVRGFGVEVMANSDNVLRGGLTPKHVDVPELLRVL 300 AALLLNR+SLAPGEAIF+ AGNLH Y+RGF VEVMANSDNVLRGGLTPKHVDVPELLRVL Sbjct 241 AALLLNRVSLAPGEAIFVSAGNLHTYLRGFAVEVMANSDNVLRGGLTPKHVDVPELLRVL 300 Query 301 DFAPTPKARLRPPIRREGLGLVFETPTDEFAATLLVLDGDHLGHEVDASSGHDGPQILLC 360 DFAPT + +LRP +RREG G ++ETPTDEFA LL L+ +++GHEVDA+ HDGPQILLC Sbjct 301 DFAPTTEDQLRPRVRREGFGRIYETPTDEFAVALLELEDEYVGHEVDATCSHDGPQILLC 360 Query 361 TEGSATVHGKCGSLTLQRGTAAWVAADDGPIRLTAGQPAKLFRATVGL 408 +G TVHGK GSL L+RG AAWVAADD PIRL A +P KLFRATVGL Sbjct 361 IQGCTTVHGKSGSLRLKRGMAAWVAADDAPIRLVAHEPTKLFRATVGL 408 >gi|15827331|ref|NP_301594.1| mannose-6-phosphate isomerase [Mycobacterium leprae TN] gi|221229809|ref|YP_002503225.1| putative mannose-6-phosphate isomerase [Mycobacterium leprae Br4923] gi|13092880|emb|CAC30274.1| putative mannose-6-phosphate isomerase [Mycobacterium leprae] gi|219932916|emb|CAR70859.1| putative mannose-6-phosphate isomerase [Mycobacterium leprae Br4923] Length=410 Score = 686 bits (1769), Expect = 0.0, Method: Compositional matrix adjust. Identities = 347/411 (85%), Positives = 369/411 (90%), Gaps = 4/411 (0%) Query 1 VELLRGALRTYAWGSRTAIAEFTGRPVPAAHPEAELWFGAHPGDPAWLQTPHGQTSLLEA 60 +ELLRGALRTYAWGSRTAIAEFTGRPVPAAHPEAELWFGAHPGD WLQ +G+TSLLEA Sbjct 1 MELLRGALRTYAWGSRTAIAEFTGRPVPAAHPEAELWFGAHPGDSVWLQAANGETSLLEA 60 Query 61 LVADPEGQLGSASRARFGDVLPFLVKVLAADEPLSLQAHPSAEQAVEGYLREERMGIPVS 120 LVADPEGQLGS SRARFGDVLPFLVKVLAADEPLSLQAHPS +QAVEGYLREER+GIPVS Sbjct 61 LVADPEGQLGSVSRARFGDVLPFLVKVLAADEPLSLQAHPSTKQAVEGYLREERLGIPVS 120 Query 121 SPVRNYRDTSHKPELLVALQPFEALAGFREAARTTELLRALAVSDLDPFIDLLSEGSDAD 180 SP RNYRDTSHKPELLVALQ FEALAGFR+++RT ELL ALAVSDLDPFI LLS+ SDAD Sbjct 121 SPERNYRDTSHKPELLVALQSFEALAGFRQSSRTAELLTALAVSDLDPFIHLLSDQSDAD 180 Query 181 GLRALFTTWITAPQPDIDVLVPAVLDGAIQYVSSGATEFGAEAKTVLELGERYPGDAGVL 240 GLRALFTTWITAPQ DID+LVPAVL+GAI YVSSGATEF AE KTV+ELGERYPGDAGVL Sbjct 181 GLRALFTTWITAPQTDIDMLVPAVLEGAIAYVSSGATEFLAEVKTVMELGERYPGDAGVL 240 Query 241 AALLLNRISLAPGEAIFLPAGNLHAYVRGFGVEVMANSDNVLRGGLTPKHVDVPELLRVL 300 A+LLLNRISL PGEAIFLPAGNLHAY+RG GVEVMANSDNVLRGGLTPKHVDVPELLRVL Sbjct 241 ASLLLNRISLTPGEAIFLPAGNLHAYLRGVGVEVMANSDNVLRGGLTPKHVDVPELLRVL 300 Query 301 DFAPTPKARLRPPIRREGLGLVFETPTDEFAATLLVLDGDHLGHEVDASSGHD---GPQI 357 DF PTP+ LRPP R EG +V+ETPTDEF LL LDGD+LGHEVDAS HD GPQI Sbjct 301 DFNPTPEEALRPPTRCEGFAVVYETPTDEFEVALLALDGDYLGHEVDASP-HDVSQGPQI 359 Query 358 LLCTEGSATVHGKCGSLTLQRGTAAWVAADDGPIRLTAGQPAKLFRATVGL 408 LLCTEG TVHGK +LT++RG A W+AADDGPIRL A QPAKLFRATVGL Sbjct 360 LLCTEGEITVHGKFQALTVERGMAVWMAADDGPIRLVAQQPAKLFRATVGL 410 >gi|254776654|ref|ZP_05218170.1| mannose-6-phosphate isomerase, class I [Mycobacterium avium subsp. avium ATCC 25291] Length=408 Score = 685 bits (1767), Expect = 0.0, Method: Compositional matrix adjust. Identities = 340/408 (84%), Positives = 370/408 (91%), Gaps = 0/408 (0%) Query 1 VELLRGALRTYAWGSRTAIAEFTGRPVPAAHPEAELWFGAHPGDPAWLQTPHGQTSLLEA 60 +ELLRGALRTYAWGSRTAIAEFT RPVPAAHPEAELWFGAHPGDPAWL+T +G+ +LL+A Sbjct 1 MELLRGALRTYAWGSRTAIAEFTERPVPAAHPEAELWFGAHPGDPAWLETDNGEITLLDA 60 Query 61 LVADPEGQLGSASRARFGDVLPFLVKVLAADEPLSLQAHPSAEQAVEGYLREERMGIPVS 120 L ADPEGQLG SRARFGDVLPFLVKVLAADEPLSLQAHPSAEQA EGYLREER+GIP++ Sbjct 61 LRADPEGQLGPGSRARFGDVLPFLVKVLAADEPLSLQAHPSAEQAAEGYLREERLGIPLN 120 Query 121 SPVRNYRDTSHKPELLVALQPFEALAGFREAARTTELLRALAVSDLDPFIDLLSEGSDAD 180 SPVRNYRDTSHKPELLVAL PFEALAGFR A+RT ELLRALAVSDLDPFI+LL + SDAD Sbjct 121 SPVRNYRDTSHKPELLVALYPFEALAGFRPASRTVELLRALAVSDLDPFIELLGDQSDAD 180 Query 181 GLRALFTTWITAPQPDIDVLVPAVLDGAIQYVSSGATEFGAEAKTVLELGERYPGDAGVL 240 GLRALFTTWITAPQPDIDV+VPAVLDGAI Y+SSGATEF AEAKTVLELGERYPGDAGVL Sbjct 181 GLRALFTTWITAPQPDIDVVVPAVLDGAIAYLSSGATEFAAEAKTVLELGERYPGDAGVL 240 Query 241 AALLLNRISLAPGEAIFLPAGNLHAYVRGFGVEVMANSDNVLRGGLTPKHVDVPELLRVL 300 AALLLNR+SLAPGEAIF+ AGNLH Y+RGF VEVMANSDNVLRGGLTPKHVDVPELLRVL Sbjct 241 AALLLNRVSLAPGEAIFVSAGNLHTYLRGFAVEVMANSDNVLRGGLTPKHVDVPELLRVL 300 Query 301 DFAPTPKARLRPPIRREGLGLVFETPTDEFAATLLVLDGDHLGHEVDASSGHDGPQILLC 360 DFAPT + +LRP +RREG G ++ETPTDEFA LL L+ +++GHEVDA+ HDGPQILLC Sbjct 301 DFAPTTEDQLRPRVRREGFGRIYETPTDEFAVALLELEDEYVGHEVDATCSHDGPQILLC 360 Query 361 TEGSATVHGKCGSLTLQRGTAAWVAADDGPIRLTAGQPAKLFRATVGL 408 +G TVHGK GSL L+RG AAWVAADD PIRL A +P KLFRATVGL Sbjct 361 IQGCTTVHGKSGSLRLKRGMAAWVAADDAPIRLVAHEPTKLFRATVGL 408 >gi|333991644|ref|YP_004524258.1| mannose-6-phosphate isomerase ManA [Mycobacterium sp. JDM601] gi|333487612|gb|AEF37004.1| mannose-6-phosphate isomerase ManA [Mycobacterium sp. JDM601] Length=422 Score = 640 bits (1652), Expect = 0.0, Method: Compositional matrix adjust. Identities = 328/422 (78%), Positives = 356/422 (85%), Gaps = 14/422 (3%) Query 1 VELLRGALRTYAWGSRTAIAEFTGRPVPAAHPEAELWFGAHPGDPAWLQTPHGQTSLLEA 60 +E LRGA+RTYAWGSRTAIAEFTGRPVPAAHPEAELW GAHPGDPAWL+T G+ SLLE Sbjct 1 MEPLRGAIRTYAWGSRTAIAEFTGRPVPAAHPEAELWLGAHPGDPAWLETATGEVSLLEV 60 Query 61 LVADPEGQLGSASRARFGDVLPFLVKVLAADEPLSLQAHPSAEQAVEGYLREERMGIPVS 120 L AD EGQLG + ARFGD LPFLVKVLAADEPLSLQAHPSA QA+EGY REER+G+PVS Sbjct 61 LTADWEGQLGPVAHARFGDRLPFLVKVLAADEPLSLQAHPSAMQAIEGYEREERLGVPVS 120 Query 121 SPVRNYRDTSHKPELLVALQPFEALAGFREAARTTELLRALAVSDLDPFIDLL------- 173 SP+RNYRDTSHKPELLVALQPFEALAGFR AART ELLRALAVSDLDPFIDLL Sbjct 121 SPIRNYRDTSHKPELLVALQPFEALAGFRPAARTVELLRALAVSDLDPFIDLLGGQTAGD 180 Query 174 -------SEGSDADGLRALFTTWITAPQPDIDVLVPAVLDGAIQYVSSGATEFGAEAKTV 226 SDADGLRALFTTWITAPQPD+DVLVPAVL+GAIQY+ S A EF AEAKTV Sbjct 181 RPALDPADAQSDADGLRALFTTWITAPQPDLDVLVPAVLEGAIQYLHSEAGEFAAEAKTV 240 Query 227 LELGERYPGDAGVLAALLLNRISLAPGEAIFLPAGNLHAYVRGFGVEVMANSDNVLRGGL 286 LELGERYPGDAGVLAALLLNRISLAPGEAIFLPAGNLH Y+ G G+EVMANSDNVLRGGL Sbjct 241 LELGERYPGDAGVLAALLLNRISLAPGEAIFLPAGNLHTYLHGVGLEVMANSDNVLRGGL 300 Query 287 TPKHVDVPELLRVLDFAPTPKARLRPPIRREGLGLVFETPTDEFAATLLVLDGDHLGHEV 346 TPKHVDVPELLRVLDF PT + LRP I +G +V++TP +EFA + L LDG HLGHE+ Sbjct 301 TPKHVDVPELLRVLDFTPTTEQALRPAIHSDGPEVVYQTPAEEFAVSRLTLDGAHLGHEL 360 Query 347 DASSGHDGPQILLCTEGSATVHGKCGSLTLQRGTAAWVAADDGPIRLTAGQPAKLFRATV 406 DA + HDGPQILLCTEGS TVH K GSL L+RG +AWV +DDGPIRL A Q A LFR+T+ Sbjct 361 DAPAHHDGPQILLCTEGSVTVHAKSGSLILRRGESAWVPSDDGPIRLLAQQQAVLFRSTI 420 Query 407 GL 408 GL Sbjct 421 GL 422 >gi|22023937|gb|AAM89255.1|AF527174_1 phosphomannose isomerase [Mycobacterium smegmatis str. MC2 155] Length=408 Score = 630 bits (1625), Expect = 1e-178, Method: Compositional matrix adjust. Identities = 312/408 (77%), Positives = 345/408 (85%), Gaps = 0/408 (0%) Query 1 VELLRGALRTYAWGSRTAIAEFTGRPVPAAHPEAELWFGAHPGDPAWLQTPHGQTSLLEA 60 + LLRGA+RTYAWGSRTAIA+FTGRP P HPEAELWFGAHP DPAWLQT G+ SLL+A Sbjct 1 MHLLRGAVRTYAWGSRTAIADFTGRPSPTVHPEAELWFGAHPADPAWLQTDDGERSLLQA 60 Query 61 LVADPEGQLGSASRARFGDVLPFLVKVLAADEPLSLQAHPSAEQAVEGYLREERMGIPVS 120 L DPEGQLGS + ARFGD LPFLVKVLAADEPLSLQAHPSA QA EG+ RE+R+ IP+S Sbjct 61 LADDPEGQLGSTAVARFGDALPFLVKVLAADEPLSLQAHPSAAQAQEGFEREDRLQIPIS 120 Query 121 SPVRNYRDTSHKPELLVALQPFEALAGFREAARTTELLRALAVSDLDPFIDLLSEGSDAD 180 SPVRNYRD SHKPELLVAL+ F ALAGFR ART EL+R LAV+DLDP+I+LLS+ SDAD Sbjct 121 SPVRNYRDRSHKPELLVALEEFHALAGFRPVARTVELMRTLAVTDLDPYINLLSDQSDAD 180 Query 181 GLRALFTTWITAPQPDIDVLVPAVLDGAIQYVSSGATEFGAEAKTVLELGERYPGDAGVL 240 GLRALFTTWITAPQPD+DVLVPAVLDGAI Y+ SG F AEAKTVLELGERYPGDAGVL Sbjct 181 GLRALFTTWITAPQPDLDVLVPAVLDGAINYIRSGEKAFAAEAKTVLELGERYPGDAGVL 240 Query 241 AALLLNRISLAPGEAIFLPAGNLHAYVRGFGVEVMANSDNVLRGGLTPKHVDVPELLRVL 300 A+LLLNRI L PGE ++LPAGNLHAY+ G GVEVMANSDNVLRGGLTPKHVDVPELLRVL Sbjct 241 ASLLLNRIVLQPGEGLYLPAGNLHAYLHGVGVEVMANSDNVLRGGLTPKHVDVPELLRVL 300 Query 301 DFAPTPKARLRPPIRREGLGLVFETPTDEFAATLLVLDGDHLGHEVDASSGHDGPQILLC 360 DF PTP+ RLRP I + LV++TP EFA ++L LDG+ LGHE+DA S HDGPQ+LLC Sbjct 301 DFTPTPEDRLRPVIVHDAKELVYQTPAPEFAVSVLRLDGEQLGHEIDAQSRHDGPQLLLC 360 Query 361 TEGSATVHGKCGSLTLQRGTAAWVAADDGPIRLTAGQPAKLFRATVGL 408 TEGS VH K G L L RG AAWVAADDGPIRLTA PA +FR TVG+ Sbjct 361 TEGSLKVHAKAGQLELSRGEAAWVAADDGPIRLTAELPAAMFRVTVGI 408 >gi|120402739|ref|YP_952568.1| mannose-6-phosphate isomerase, class I [Mycobacterium vanbaalenii PYR-1] gi|119955557|gb|ABM12562.1| mannose-6-phosphate isomerase, type 1 [Mycobacterium vanbaalenii PYR-1] Length=408 Score = 602 bits (1552), Expect = 4e-170, Method: Compositional matrix adjust. Identities = 294/408 (73%), Positives = 342/408 (84%), Gaps = 0/408 (0%) Query 1 VELLRGALRTYAWGSRTAIAEFTGRPVPAAHPEAELWFGAHPGDPAWLQTPHGQTSLLEA 60 + LL+GA+RTYAWGSRTAIAEF G P P AHPEAELWFGAHPGDPA+L+T G SLL+A Sbjct 1 MHLLKGAVRTYAWGSRTAIAEFVGAPSPTAHPEAELWFGAHPGDPAYLKTDDGDRSLLDA 60 Query 61 LVADPEGQLGSASRARFGDVLPFLVKVLAADEPLSLQAHPSAEQAVEGYLREERMGIPVS 120 L ADPEG+LG+A R RFGD LPFLVKVLAADEPLSLQAHPS EQAVEG+ RE+R+GIP+S Sbjct 61 LRADPEGELGAAVRGRFGDTLPFLVKVLAADEPLSLQAHPSTEQAVEGFAREDRLGIPIS 120 Query 121 SPVRNYRDTSHKPELLVALQPFEALAGFREAARTTELLRALAVSDLDPFIDLLSEGSDAD 180 +P RNYRD SHKPE++VAL FEALAGFR AAR+ EL+RAL V+DLDPFI LL D D Sbjct 121 APDRNYRDRSHKPEIIVALSQFEALAGFRPAARSVELMRALGVADLDPFISLLHGQRDED 180 Query 181 GLRALFTTWITAPQPDIDVLVPAVLDGAIQYVSSGATEFGAEAKTVLELGERYPGDAGVL 240 GLRALFTTWIT PQPD+DVLVPAV+DGAI YV SG EF EAKTVLELGERYPGDAGVL Sbjct 181 GLRALFTTWITFPQPDLDVLVPAVIDGAIGYVRSGEREFAREAKTVLELGERYPGDAGVL 240 Query 241 AALLLNRISLAPGEAIFLPAGNLHAYVRGFGVEVMANSDNVLRGGLTPKHVDVPELLRVL 300 ++LLNR+SLAPGEA++LPAGNLHAY+ G GVEVMANSDNVLRGGLTPKHVDVPELLRVL Sbjct 241 CSMLLNRLSLAPGEALYLPAGNLHAYLHGIGVEVMANSDNVLRGGLTPKHVDVPELLRVL 300 Query 301 DFAPTPKARLRPPIRREGLGLVFETPTDEFAATLLVLDGDHLGHEVDASSGHDGPQILLC 360 DF P +RP R+G +V+ TP EF+ ++L ++G+ LGHE+DA + HDGPQILLC Sbjct 301 DFTPAEDVYVRPETVRDGTEIVYPTPAPEFSVSVLGIEGERLGHEIDAPTCHDGPQILLC 360 Query 361 TEGSATVHGKCGSLTLQRGTAAWVAADDGPIRLTAGQPAKLFRATVGL 408 T+G+ATVH K ++ L++G AAWV+ADDGPIRL A +P +LFR TVG+ Sbjct 361 TQGAATVHAKADAVVLEKGAAAWVSADDGPIRLVAQEPTRLFRVTVGI 408 >gi|145225302|ref|YP_001135980.1| mannose-6-phosphate isomerase, class I [Mycobacterium gilvum PYR-GCK] gi|145217788|gb|ABP47192.1| mannose-6-phosphate isomerase, type 1 [Mycobacterium gilvum PYR-GCK] Length=408 Score = 602 bits (1551), Expect = 5e-170, Method: Compositional matrix adjust. Identities = 300/408 (74%), Positives = 339/408 (84%), Gaps = 0/408 (0%) Query 1 VELLRGALRTYAWGSRTAIAEFTGRPVPAAHPEAELWFGAHPGDPAWLQTPHGQTSLLEA 60 + LLRGA+RTYAWGSRTAIAEF G P P HPEAELWFGAHPGDPAWLQT G+ SLL+A Sbjct 1 MHLLRGAVRTYAWGSRTAIAEFVGGPSPTPHPEAELWFGAHPGDPAWLQTDDGERSLLDA 60 Query 61 LVADPEGQLGSASRARFGDVLPFLVKVLAADEPLSLQAHPSAEQAVEGYLREERMGIPVS 120 L ADPEG+LGSA R RFGD LPFLVKVLAADEPLSLQAHPS EQAVEG+ RE+RMGIPV+ Sbjct 61 LRADPEGELGSAVRGRFGDTLPFLVKVLAADEPLSLQAHPSTEQAVEGFAREDRMGIPVT 120 Query 121 SPVRNYRDTSHKPELLVALQPFEALAGFREAARTTELLRALAVSDLDPFIDLLSEGSDAD 180 +P RNYRD SHKPE++VAL FEALAGFR AAR+ EL+ AL V+DLDP+I LLS D D Sbjct 121 APDRNYRDPSHKPEIIVALSQFEALAGFRPAARSVELMTALGVADLDPYIGLLSGQRDED 180 Query 181 GLRALFTTWITAPQPDIDVLVPAVLDGAIQYVSSGATEFGAEAKTVLELGERYPGDAGVL 240 GLRALFTTWIT PQPD+D+LVPAV+DGAI YV SGA EF EAKTVLELGERYPGDAGVL Sbjct 181 GLRALFTTWITCPQPDLDLLVPAVIDGAINYVRSGAQEFAREAKTVLELGERYPGDAGVL 240 Query 241 AALLLNRISLAPGEAIFLPAGNLHAYVRGFGVEVMANSDNVLRGGLTPKHVDVPELLRVL 300 A+LLLNR+SLAPGEA++LPAGNLHAY+ G GVEVMANSDNVLRGGLTPKHVDVPELLRVL Sbjct 241 ASLLLNRLSLAPGEALYLPAGNLHAYLEGVGVEVMANSDNVLRGGLTPKHVDVPELLRVL 300 Query 301 DFAPTPKARLRPPIRREGLGLVFETPTDEFAATLLVLDGDHLGHEVDASSGHDGPQILLC 360 DF P + P R G +V+ TP EFA ++L LDG+ LGHE+DA + HDGPQILLC Sbjct 301 DFTPAEDVLVVPETIRGGAEIVYPTPAPEFAVSILHLDGESLGHEIDAPTRHDGPQILLC 360 Query 361 TEGSATVHGKCGSLTLQRGTAAWVAADDGPIRLTAGQPAKLFRATVGL 408 T+G+ATV ++ L+RG AAWV A DGPIRL+A +P KLFR TVG+ Sbjct 361 TDGAATVQANGSAVALKRGAAAWVGAGDGPIRLSAQEPTKLFRVTVGI 408 >gi|315445600|ref|YP_004078479.1| mannose-6-phosphate isomerase, type 1 [Mycobacterium sp. Spyr1] gi|315263903|gb|ADU00645.1| mannose-6-phosphate isomerase, type 1 [Mycobacterium sp. Spyr1] Length=408 Score = 600 bits (1548), Expect = 1e-169, Method: Compositional matrix adjust. Identities = 299/408 (74%), Positives = 339/408 (84%), Gaps = 0/408 (0%) Query 1 VELLRGALRTYAWGSRTAIAEFTGRPVPAAHPEAELWFGAHPGDPAWLQTPHGQTSLLEA 60 + LLRGA+RTYAWGSRTAIAEF G P P HPEAELWFGAHPGDPAWLQT G+ SLL+A Sbjct 1 MHLLRGAVRTYAWGSRTAIAEFVGGPSPTPHPEAELWFGAHPGDPAWLQTDDGERSLLDA 60 Query 61 LVADPEGQLGSASRARFGDVLPFLVKVLAADEPLSLQAHPSAEQAVEGYLREERMGIPVS 120 L ADPEG+LGSA R RFGD LPFLVKVLAADEPLSLQAHPS EQA+EG+ RE+RMGIPVS Sbjct 61 LRADPEGELGSAVRGRFGDTLPFLVKVLAADEPLSLQAHPSTEQAIEGFAREDRMGIPVS 120 Query 121 SPVRNYRDTSHKPELLVALQPFEALAGFREAARTTELLRALAVSDLDPFIDLLSEGSDAD 180 +P RNYRD SHKPE++VAL FEALAGFR AAR+ +L+ AL V+DLDP+I LLS D D Sbjct 121 APDRNYRDPSHKPEIIVALSQFEALAGFRPAARSVDLMAALGVADLDPYIGLLSGQRDED 180 Query 181 GLRALFTTWITAPQPDIDVLVPAVLDGAIQYVSSGATEFGAEAKTVLELGERYPGDAGVL 240 GLRALFTTWIT PQPD+D+LVPAV+DGAI YV SGA EF EAKTVLELGERYPGDAGVL Sbjct 181 GLRALFTTWITCPQPDLDLLVPAVIDGAINYVRSGAQEFAREAKTVLELGERYPGDAGVL 240 Query 241 AALLLNRISLAPGEAIFLPAGNLHAYVRGFGVEVMANSDNVLRGGLTPKHVDVPELLRVL 300 A+LLLNR+SLAPGEA++LPAGNLHAY+ G GVEVMANSDNVLRGGLTPKHVDVPELLRVL Sbjct 241 ASLLLNRLSLAPGEALYLPAGNLHAYLEGVGVEVMANSDNVLRGGLTPKHVDVPELLRVL 300 Query 301 DFAPTPKARLRPPIRREGLGLVFETPTDEFAATLLVLDGDHLGHEVDASSGHDGPQILLC 360 DF P + P R G +V+ TP EFA ++L LDG+ LGHE+DA + HDGPQILLC Sbjct 301 DFTPAEDVLVVPEAIRGGAEIVYPTPAPEFAVSILHLDGESLGHEIDAPTRHDGPQILLC 360 Query 361 TEGSATVHGKCGSLTLQRGTAAWVAADDGPIRLTAGQPAKLFRATVGL 408 T+G+ATV ++ L+RG AAWV A DGPIRL+A +P KLFR TVG+ Sbjct 361 TDGAATVQANGSAVALKRGAAAWVGAGDGPIRLSAQEPTKLFRVTVGI 408 >gi|126433968|ref|YP_001069659.1| mannose-6-phosphate isomerase [Mycobacterium sp. JLS] gi|126233768|gb|ABN97168.1| mannose-6-phosphate isomerase, type 1 [Mycobacterium sp. JLS] Length=409 Score = 600 bits (1546), Expect = 2e-169, Method: Compositional matrix adjust. Identities = 301/409 (74%), Positives = 340/409 (84%), Gaps = 1/409 (0%) Query 1 VELLRGALRTYAWGSRTAIAEFTGRPVPAAHPEAELWFGAHPGDPAWLQTPHGQTSLLEA 60 + LLRGA+RTYAWGSRTAIA+FTGRP P HPEAELWFGAHPGDPA+LQ G+ SLLEA Sbjct 1 MHLLRGAVRTYAWGSRTAIADFTGRPSPTPHPEAELWFGAHPGDPAYLQGEDGEVSLLEA 60 Query 61 LVADPEGQLGSASRARFGDVLPFLVKVLAADEPLSLQAHPSAEQAVEGYLREERMGIPVS 120 L A+P GQLG+A RFG+ LPFLVKVLAADEPLSLQAHPSA+QA EGY REER+GIPVS Sbjct 61 LRANPAGQLGAAVVDRFGETLPFLVKVLAADEPLSLQAHPSAQQAAEGYDREERLGIPVS 120 Query 121 SPVRNYRDTSHKPELLVALQPFEALAGFREAARTTELLRALAVSDLDPFIDLLSEGSDAD 180 +P+RNYRD SHKPELLVAL FEALAGFR ART +L+RAL V +LDPF++LL S+ D Sbjct 121 APMRNYRDRSHKPELLVALDRFEALAGFRPVARTVDLMRALGVPELDPFVNLLHGQSEPD 180 Query 181 GLRALFTTWITAPQPDIDVLVPAVLDGAIQYVSSGATEFGAEAKTVLELGERYPGDAGVL 240 GLRALFTTWITAPQPD+DVLVPAVLDGAI Y+ +G TEF AE KTVLELGERYPGDAGVL Sbjct 181 GLRALFTTWITAPQPDLDVLVPAVLDGAIDYIRAGQTEFEAEVKTVLELGERYPGDAGVL 240 Query 241 AALLLNRISLAPGEAIFLPAGNLHAYVRGFGVEVMANSDNVLRGGLTPKHVDVPELLRVL 300 AA+LLNRI+L+PGE I+LPAGNLHAY+ G GVEVMANSDNVLRGGLTPKHVDVPELLRVL Sbjct 241 AAMLLNRITLSPGEGIYLPAGNLHAYLHGVGVEVMANSDNVLRGGLTPKHVDVPELLRVL 300 Query 301 DFAPTPKARLRPPIRREGLGLVFETPTDEFAATLLVLDGDHLGHEVDASSGHDGPQILLC 360 DF PTP LRP R+G+G + TP EFA ++L LDGD++GHE+DA S HDGPQ+L+C Sbjct 301 DFTPTPDLVLRPETARDGIGFEYRTPAPEFAVSVLRLDGDNVGHELDAPSPHDGPQVLVC 360 Query 361 TEGSATVHGKCGS-LTLQRGTAAWVAADDGPIRLTAGQPAKLFRATVGL 408 TEG A V K G LTL RG A WV ADDGPI+L A P +FR TVG+ Sbjct 361 TEGCAEVRAKGGDMLTLPRGAAGWVTADDGPIQLLAAAPTTVFRVTVGI 409 >gi|108798301|ref|YP_638498.1| mannose-6-phosphate isomerase [Mycobacterium sp. MCS] gi|119867397|ref|YP_937349.1| mannose-6-phosphate isomerase [Mycobacterium sp. KMS] gi|108768720|gb|ABG07442.1| mannose-6-phosphate isomerase, type 1 [Mycobacterium sp. MCS] gi|119693486|gb|ABL90559.1| mannose-6-phosphate isomerase, type 1 [Mycobacterium sp. KMS] Length=409 Score = 598 bits (1543), Expect = 4e-169, Method: Compositional matrix adjust. Identities = 302/409 (74%), Positives = 339/409 (83%), Gaps = 1/409 (0%) Query 1 VELLRGALRTYAWGSRTAIAEFTGRPVPAAHPEAELWFGAHPGDPAWLQTPHGQTSLLEA 60 + LLRGA+RTYAWGSRTAIA+FTGRP P HPEAELWFGAHPGDPA+LQ G+ SLLEA Sbjct 1 MHLLRGAVRTYAWGSRTAIADFTGRPSPTPHPEAELWFGAHPGDPAYLQGEAGEVSLLEA 60 Query 61 LVADPEGQLGSASRARFGDVLPFLVKVLAADEPLSLQAHPSAEQAVEGYLREERMGIPVS 120 L ADP GQLG+A RFG+ LPFLVKVLAADEPLSLQAHPSA+QA EGY REER+GIPVS Sbjct 61 LRADPAGQLGAAVVDRFGETLPFLVKVLAADEPLSLQAHPSAQQAAEGYDREERLGIPVS 120 Query 121 SPVRNYRDTSHKPELLVALQPFEALAGFREAARTTELLRALAVSDLDPFIDLLSEGSDAD 180 +P+RNYRD SHKPELLVAL FEALAGFR ART +L+RAL V +LDPF++LL S+ D Sbjct 121 APMRNYRDRSHKPELLVALDRFEALAGFRPVARTVDLMRALGVPELDPFVNLLHGQSEPD 180 Query 181 GLRALFTTWITAPQPDIDVLVPAVLDGAIQYVSSGATEFGAEAKTVLELGERYPGDAGVL 240 GLRALFTTWITAPQPD+DVLVPAVLDGAI Y+ +G TEF AE KTVLELGERYPGDAGVL Sbjct 181 GLRALFTTWITAPQPDLDVLVPAVLDGAIDYIRAGQTEFEAEVKTVLELGERYPGDAGVL 240 Query 241 AALLLNRISLAPGEAIFLPAGNLHAYVRGFGVEVMANSDNVLRGGLTPKHVDVPELLRVL 300 AA+LLNRI+L+PGE I+LPAGNLHAY+ G GVEVMANSDNVLRGGLTPKHVDVPELLRVL Sbjct 241 AAMLLNRITLSPGEGIYLPAGNLHAYLHGVGVEVMANSDNVLRGGLTPKHVDVPELLRVL 300 Query 301 DFAPTPKARLRPPIRREGLGLVFETPTDEFAATLLVLDGDHLGHEVDASSGHDGPQILLC 360 DF PTP LRP REG+ + TP EFA ++L LDGD++GHE+DA S HDGPQ+L+C Sbjct 301 DFTPTPDLVLRPETAREGIEFEYRTPAPEFAVSVLRLDGDNVGHELDAPSPHDGPQVLVC 360 Query 361 TEGSATVHGKCGS-LTLQRGTAAWVAADDGPIRLTAGQPAKLFRATVGL 408 TEG A V K G LTL RG A WV ADDGPI+L A P +FR TVG+ Sbjct 361 TEGCAEVRAKGGDVLTLPRGAAGWVTADDGPIQLLAAVPTTVFRVTVGI 409 >gi|118468938|ref|YP_886206.1| mannose-6-phosphate isomerase, class I [Mycobacterium smegmatis str. MC2 155] gi|118170225|gb|ABK71121.1| mannose-6-phosphate isomerase, class I [Mycobacterium smegmatis str. MC2 155] Length=379 Score = 583 bits (1502), Expect = 2e-164, Method: Compositional matrix adjust. Identities = 289/378 (77%), Positives = 319/378 (85%), Gaps = 0/378 (0%) Query 31 HPEAELWFGAHPGDPAWLQTPHGQTSLLEALVADPEGQLGSASRARFGDVLPFLVKVLAA 90 HPEAELWFGAHP DPAWLQT G+ SLL+AL DPEGQLGS + ARFGD LPFLVKVLAA Sbjct 2 HPEAELWFGAHPADPAWLQTDDGERSLLQALADDPEGQLGSTAVARFGDALPFLVKVLAA 61 Query 91 DEPLSLQAHPSAEQAVEGYLREERMGIPVSSPVRNYRDTSHKPELLVALQPFEALAGFRE 150 DEPLSLQAHPSA QA EG+ RE+R+ IP+SSPVRNYRD SHKPELLVAL+ F ALAGFR Sbjct 62 DEPLSLQAHPSAAQAQEGFEREDRLQIPISSPVRNYRDRSHKPELLVALEEFHALAGFRP 121 Query 151 AARTTELLRALAVSDLDPFIDLLSEGSDADGLRALFTTWITAPQPDIDVLVPAVLDGAIQ 210 ART EL+R LAV+DLDP+I+LLS+ SDADGLRALFTTWITAPQPD+DVLVPAVLDGAI Sbjct 122 VARTVELMRTLAVTDLDPYINLLSDQSDADGLRALFTTWITAPQPDLDVLVPAVLDGAIN 181 Query 211 YVSSGATEFGAEAKTVLELGERYPGDAGVLAALLLNRISLAPGEAIFLPAGNLHAYVRGF 270 Y+ SG F AEAKTVLELGERYPGDAGVLA+LLLNRI L PGE ++LPAGNLHAY+ G Sbjct 182 YIRSGEKAFAAEAKTVLELGERYPGDAGVLASLLLNRIVLQPGEGLYLPAGNLHAYLHGV 241 Query 271 GVEVMANSDNVLRGGLTPKHVDVPELLRVLDFAPTPKARLRPPIRREGLGLVFETPTDEF 330 GVEVMANSDNVLRGGLTPKHVDVPELLRVLDF PTP+ RLRP I + LV++TP EF Sbjct 242 GVEVMANSDNVLRGGLTPKHVDVPELLRVLDFTPTPEDRLRPVIVHDAKELVYQTPAPEF 301 Query 331 AATLLVLDGDHLGHEVDASSGHDGPQILLCTEGSATVHGKCGSLTLQRGTAAWVAADDGP 390 A ++L LDG+ LGHE+DA S HDGPQ+LLCTEGS VH K G L L RG AAWVAADDGP Sbjct 302 AVSVLRLDGEQLGHEIDAQSRHDGPQLLLCTEGSLKVHAKAGQLELSRGEAAWVAADDGP 361 Query 391 IRLTAGQPAKLFRATVGL 408 IRLTA PA +FR TVG+ Sbjct 362 IRLTAELPAAMFRVTVGI 379 >gi|169630681|ref|YP_001704330.1| mannose-6-phosphate isomerase ManA [Mycobacterium abscessus ATCC 19977] gi|169242648|emb|CAM63676.1| Probable mannose-6-phosphate isomerase ManA [Mycobacterium abscessus] Length=405 Score = 502 bits (1293), Expect = 4e-140, Method: Compositional matrix adjust. Identities = 257/406 (64%), Positives = 304/406 (75%), Gaps = 5/406 (1%) Query 1 VELLRGALRTYAWGSRTAIAEFTGRPVPAAHPEAELWFGAHPGDPAWLQTPHGQTSLLEA 60 + LLRGA+RTYAWGSRTAIAEFTGRP P HPEAELW GAHP DPA+L+T G SLLE Sbjct 1 MNLLRGAIRTYAWGSRTAIAEFTGRPTPTPHPEAELWLGAHPADPAYLETGGGAESLLEV 60 Query 61 LVADPEGQLGSASRARFGDVLPFLVKVLAADEPLSLQAHPSAEQAVEGYLREERMGIPVS 120 + ADP GQLG+AS A FGD LPFL+KVLAADEPLSLQAHPSA+QA +G+ REE G+P++ Sbjct 61 VAADPTGQLGAASVAEFGDQLPFLLKVLAADEPLSLQAHPSAQQAADGFAREEAAGVPLN 120 Query 121 SPVRNYRDTSHKPELLVALQPFEALAGFREAARTTELLRALAVSDLDPFIDLLSEGSDAD 180 SPVRNYRD +HKPEL+VAL FEALAGFR+ T +L RAL V L P+++LL+ SDAD Sbjct 121 SPVRNYRDRNHKPELVVALDRFEALAGFRDPGDTVDLFRALDVEALTPYVNLLAGQSDAD 180 Query 181 GLRALFTTWITAPQPDIDVLVPAVLDGAIQYVSSGATEFGAEAKTVLELGERYPGDAGVL 240 GLRALFTTWIT PQP +DVLVPAVLDGA++Y+SS F EA+T+LELGERYP DAGVL Sbjct 181 GLRALFTTWITLPQPSLDVLVPAVLDGAVRYLSSDDVRFVGEARTLLELGERYPADAGVL 240 Query 241 AALLLNRISLAPGEAIFLPAGNLHAYVRGFGVEVMANSDNVLRGGLTPKHVDVPELLRVL 300 A+LLLNR++L PGE I+LPAGNLHAY+RG VE+MANSDNVLRGGLTPKHVDVPELLRVL Sbjct 241 ASLLLNRLTLEPGEGIYLPAGNLHAYLRGLAVEIMANSDNVLRGGLTPKHVDVPELLRVL 300 Query 301 DFAPTPKARLRPPIRREGLGLVFETPTDEFAATLLVLDGDHLGHEVDASSGHDGPQILLC 360 DF+P +A L +G + TP EFA + L G GP+ILLC Sbjct 301 DFSPASEAHLHVETVTDGAQTRYRTPAREFALSRFDLAAGE-----PTQVGIKGPRILLC 355 Query 361 TEGSATVHGKCGSLTLQRGTAAWVAADDGPIRLTAGQPAKLFRATV 406 T+G T+ G L ++ G + WV AD G + LT A++F ATV Sbjct 356 TQGDVTLDGSGAGLKVRAGQSVWVPADGGSVTLTGRSDARVFMATV 401 >gi|289571482|ref|ZP_06451709.1| mannose-6-phosphate isomerase manA [Mycobacterium tuberculosis T17] gi|289545236|gb|EFD48884.1| mannose-6-phosphate isomerase manA [Mycobacterium tuberculosis T17] Length=369 Score = 463 bits (1192), Expect = 2e-128, Method: Compositional matrix adjust. Identities = 231/231 (100%), Positives = 231/231 (100%), Gaps = 0/231 (0%) Query 178 DADGLRALFTTWITAPQPDIDVLVPAVLDGAIQYVSSGATEFGAEAKTVLELGERYPGDA 237 DADGLRALFTTWITAPQPDIDVLVPAVLDGAIQYVSSGATEFGAEAKTVLELGERYPGDA Sbjct 139 DADGLRALFTTWITAPQPDIDVLVPAVLDGAIQYVSSGATEFGAEAKTVLELGERYPGDA 198 Query 238 GVLAALLLNRISLAPGEAIFLPAGNLHAYVRGFGVEVMANSDNVLRGGLTPKHVDVPELL 297 GVLAALLLNRISLAPGEAIFLPAGNLHAYVRGFGVEVMANSDNVLRGGLTPKHVDVPELL Sbjct 199 GVLAALLLNRISLAPGEAIFLPAGNLHAYVRGFGVEVMANSDNVLRGGLTPKHVDVPELL 258 Query 298 RVLDFAPTPKARLRPPIRREGLGLVFETPTDEFAATLLVLDGDHLGHEVDASSGHDGPQI 357 RVLDFAPTPKARLRPPIRREGLGLVFETPTDEFAATLLVLDGDHLGHEVDASSGHDGPQI Sbjct 259 RVLDFAPTPKARLRPPIRREGLGLVFETPTDEFAATLLVLDGDHLGHEVDASSGHDGPQI 318 Query 358 LLCTEGSATVHGKCGSLTLQRGTAAWVAADDGPIRLTAGQPAKLFRATVGL 408 LLCTEGSATVHGKCGSLTLQRGTAAWVAADDGPIRLTAGQPAKLFRATVGL Sbjct 319 LLCTEGSATVHGKCGSLTLQRGTAAWVAADDGPIRLTAGQPAKLFRATVGL 369 >gi|296138916|ref|YP_003646159.1| mannose-6-phosphate isomerase, class I [Tsukamurella paurometabola DSM 20162] gi|296027050|gb|ADG77820.1| mannose-6-phosphate isomerase, class I [Tsukamurella paurometabola DSM 20162] Length=407 Score = 446 bits (1146), Expect = 5e-123, Method: Compositional matrix adjust. Identities = 241/408 (60%), Positives = 281/408 (69%), Gaps = 4/408 (0%) Query 1 VELLRGALRTYAWGSRTAIAEFTGRPVPAAHPEAELWFGAHPGDPAWLQTPHGQTSLLEA 60 ++ + G +R YAWGSRT +A GRPVP+ HPEAELWFGAHP DPA L T LL Sbjct 1 MQRVEGVIRPYAWGSRTVLAAMQGRPVPSNHPEAELWFGAHPADPARLDD---GTDLLGT 57 Query 61 LVADPEGQLGSASRARFGDVLPFLVKVLAADEPLSLQAHPSAEQAVEGYLREERMGIPVS 120 + DPEG+LG+ RA FGD LP+LVKVLAADEPLSLQAHPSAEQA EG+ RE GIP+ Sbjct 58 ISGDPEGELGAPCRAEFGDTLPYLVKVLAADEPLSLQAHPSAEQAREGFARENAAGIPLD 117 Query 121 SPVRNYRDTSHKPELLVALQPFEALAGFREAARTTELLRALAVSDLDPFIDLLSEGSDAD 180 P RNYRD HKPE++VAL FEALAGFR+ A T ELLRALAV +LD ++ LL+ D+ Sbjct 118 DPERNYRDPFHKPEVVVALSRFEALAGFRDPAATMELLRALAVPELDTYLGLLAGQPDSQ 177 Query 181 GLRALFTTWITAPQPDIDVLVPAVLDGAIQYVSSGATEFGAEAKTVLELGERYPGDAGVL 240 GLRAL TTWIT PQP + LVP VL G ++Y+ SGA F EAK L LGERYP DAGVL Sbjct 178 GLRALVTTWITLPQPALASLVPEVLAGCVRYLESGADRFRGEAKLALTLGERYPDDAGVL 237 Query 241 AALLLNRISLAPGEAIFLPAGNLHAYVRGFGVEVMANSDNVLRGGLTPKHVDVPELLRVL 300 AALLLNRI L PGEA++L AGNLHAY+ G VEVMANSDNVLRGGLTPKHVDVPELLRVL Sbjct 238 AALLLNRIELQPGEALYLAAGNLHAYISGAAVEVMANSDNVLRGGLTPKHVDVPELLRVL 297 Query 301 DFAPTPKARLRPPIRREGLGLVFETPTDEFAATLLVLDGDHLGHEVDASSGHDGPQILLC 360 DFAP A L P G +VF TP EF + + LDG L GPQ+L+ Sbjct 298 DFAPREPAELAPTTSVVGPEVVFATPAPEFRVSRVRLDGTALKRAASVELDARGPQLLVV 357 Query 361 TEGSATVHGKCGSLTLQRGTAAWVAADDGPIRLTAGQP-AKLFRATVG 407 T G+ TV S+ + G+ W+ A D + +TA P A+ FR VG Sbjct 358 TAGTITVRSAGRSVDIAAGSGLWMPASDPGVVVTAHSPAAEFFRTLVG 405 >gi|325675686|ref|ZP_08155370.1| mannose-6-phosphate isomerase [Rhodococcus equi ATCC 33707] gi|325553657|gb|EGD23335.1| mannose-6-phosphate isomerase [Rhodococcus equi ATCC 33707] Length=412 Score = 444 bits (1143), Expect = 9e-123, Method: Compositional matrix adjust. Identities = 243/409 (60%), Positives = 288/409 (71%), Gaps = 6/409 (1%) Query 4 LRGALRTYAWGSRTAIAEFTGRPVPAAHPEAELWFGAHPGDPAWLQTPHGQTSLLEALVA 63 L GALR+YAWGSRTA+AE GRP P+AHPEAELW GAHPGDPA + G SL + + A Sbjct 4 LEGALRSYAWGSRTALAELCGRPSPSAHPEAELWLGAHPGDPAHVIEDGGTRSLRDVIDA 63 Query 64 DPEGQLGSASRARFGDVLPFLVKVLAADEPLSLQAHPSAEQAVEGYLREERMGIPVSSPV 123 P +LG S A+FG+ LPFL+KVLAA+EPLSLQAHPSAEQA EG+ RE+ +GIPV S Sbjct 64 APLSELGERSVAQFGERLPFLLKVLAAEEPLSLQAHPSAEQAREGFAREDAVGIPVDSAE 123 Query 124 RNYRDTSHKPELLVALQPFEALAGFREAARTTELLRALAVSDLDPFIDLLSEGSDADGLR 183 RNYRD SHKPEL+VAL FEALAGFR+ RT L+AL V L P++ LL+ D DGLR Sbjct 124 RNYRDASHKPELVVALTRFEALAGFRDPHRTVRFLQALEVEQLAPYVGLLAGQPDPDGLR 183 Query 184 ALFTTWITAPQPDIDVLVPAVLDGAIQYVS---SGATEFGAEAKTVLELGERYPGDAGVL 240 ALFTTWIT P P + L+P VLDG ++Y+S + EF EA+T LEL E YPGDAGVL Sbjct 184 ALFTTWITLPSPALSALLPPVLDGCVRYLSRPDAAEAEFVPEARTALELSEGYPGDAGVL 243 Query 241 AALLLNRISLAPGEAIFLPAGNLHAYVRGFGVEVMANSDNVLRGGLTPKHVDVPELLRVL 300 AALLLNRI+L PG+ +FL AGNLHAY+ G VE+MANSDNVLRGGLTPKHVDVPELLRVL Sbjct 244 AALLLNRITLEPGQGLFLAAGNLHAYLHGTAVEIMANSDNVLRGGLTPKHVDVPELLRVL 303 Query 301 DFAPTPKARLRP-PIRREGLGLVFETPTDEFAATLLVLDGDHLGHEVDASSGHDGPQILL 359 DF L P P R G + + TP EF T + LD G EV + DGPQILL Sbjct 304 DFDSVDVPLLAPAPTGRPG-EVAYATPAAEFVLTRIDLDASDAGSEVSVTIEPDGPQILL 362 Query 360 CTEGSATVHGKCGSLTLQRGTAAWVAADDGPIRLTA-GQPAKLFRATVG 407 CT G+A + SL L+RG AAW++A D + + A ++FRA VG Sbjct 363 CTSGAAKLGCGPHSLVLERGGAAWISASDNEVHIQACADDTQIFRAGVG 411 >gi|54026600|ref|YP_120842.1| putative mannose-6-phosphate isomerase [Nocardia farcinica IFM 10152] gi|54018108|dbj|BAD59478.1| putative mannose-6-phosphate isomerase [Nocardia farcinica IFM 10152] Length=407 Score = 442 bits (1136), Expect = 6e-122, Method: Compositional matrix adjust. Identities = 245/408 (61%), Positives = 298/408 (74%), Gaps = 11/408 (2%) Query 4 LRGALRTYAWGSRTAIAEFTGRPVPAAHPEAELWFGAHPGDPAWLQTPHGQT-SLLEALV 62 L GALR+YAWGSRTA+AE GRPVP+AHPEAELWFGAHP DPA++ G T SLL+ + Sbjct 4 LVGALRSYAWGSRTALAELCGRPVPSAHPEAELWFGAHPADPAYVTLAEGTTKSLLDLVA 63 Query 63 ADPEGQLGSASRARFGDVLPFLVKVLAADEPLSLQAHPSAEQAVEGYLREERMGIPVSSP 122 ADPE +LG+A A+FGD LPFL+K+LAA+EPLSLQAHPSAEQA G+ RE R G+P+ SP Sbjct 64 ADPERELGAAG-AQFGDKLPFLLKILAAEEPLSLQAHPSAEQARAGFERENRTGVPLDSP 122 Query 123 VRNYRDTSHKPELLVALQPFEALAGFREAARTTELLRALAVSDLDPFIDLLSEGSDADGL 182 +RNYRD +HKPEL+VAL FEALAGFR RT EL RALAV +L+ + DLL+ D+ GL Sbjct 123 MRNYRDDNHKPELVVALDRFEALAGFRAPERTVELFRALAVPELEQYADLLAAQPDSAGL 182 Query 183 RALFTTWITAPQPDIDVLVPAVLDGAIQYVS-SGATEFGAEAKTVLELGERYPGDAGVLA 241 R LFTTWIT PQP + L+PAVLDG ++Y+S G F AEA+T LEL E YPGDAGVLA Sbjct 183 RTLFTTWITLPQPVLATLLPAVLDGCVRYLSGKGKRPFVAEARTALELAEVYPGDAGVLA 242 Query 242 ALLLNRISLAPGEAIFLPAGNLHAYVRGFGVEVMANSDNVLRGGLTPKHVDVPELLRVLD 301 ALLLNR++L PG+A+FL AGNLHAY+RG GVE+MANSDNVLRGGLTPKHVDVPELLR+LD Sbjct 243 ALLLNRLTLEPGQALFLDAGNLHAYLRGVGVEIMANSDNVLRGGLTPKHVDVPELLRILD 302 Query 302 FAPTPKARLRPPIRREGLGLVFETPTDEFAATLL-VLDGDHLGHEVDASSGHDGPQILLC 360 F P + P +G + + TP EFA +++G DA GP I+LC Sbjct 303 FEPIELPVVLPEPGGDG-SVHYRTPAPEFALRRFDLVEGAGQVPLTDA-----GPGIVLC 356 Query 361 TEGSATVHGKCGSLTLQRGTAAWVAADDGPIRLTA-GQPAKLFRATVG 407 T G+ + LT+ RG+AAW++A D IR A PA++F A VG Sbjct 357 TAGTVLLRHGDDELTVGRGSAAWISAADSDIRARAVDGPAQVFCACVG 404 >gi|226365789|ref|YP_002783572.1| mannose-6-phosphate isomerase [Rhodococcus opacus B4] gi|226244279|dbj|BAH54627.1| mannose-6-phosphate isomerase [Rhodococcus opacus B4] Length=410 Score = 440 bits (1131), Expect = 2e-121, Method: Compositional matrix adjust. Identities = 237/407 (59%), Positives = 288/407 (71%), Gaps = 7/407 (1%) Query 4 LRGALRTYAWGSRTAIAEFTGRPVPAAHPEAELWFGAHPGDPAWLQTPHGQTSLLEALVA 63 L GALR+YAWGSRTAIA+ G PVP AHPEAELW GAHPGDPA + T G SLL+ + + Sbjct 4 LEGALRSYAWGSRTAIAQLRGLPVPTAHPEAELWLGAHPGDPARVITDEGPRSLLDLVHS 63 Query 64 DPEGQLGSASRARFGDVLPFLVKVLAADEPLSLQAHPSAEQAVEGYLREERMGIPVSSPV 123 +PE QLG S FG+ LPFL+K+LA++EPLSLQAHPSAEQA EG+ RE +GIP+ S V Sbjct 64 EPERQLGKRSVETFGERLPFLLKLLASEEPLSLQAHPSAEQAWEGFARENEVGIPLESSV 123 Query 124 RNYRDTSHKPELLVALQPFEALAGFREAARTTELLRALAVSDLDPFIDLLSEGSDADGLR 183 RNY+D SHKPEL+VAL F ALAGFR+ RT +LL A+AV +L P++ L++ D+DGLR Sbjct 124 RNYKDASHKPELVVALSRFHALAGFRDPQRTVKLLEAIAVPELQPYVGLIAGQPDSDGLR 183 Query 184 ALFTTWITAPQPDIDVLVPAVLDGAIQYVSSGAT-EFGAEAKTVLELGERYPGDAGVLAA 242 ALFTTWIT PQP + L+P VLDG + Y+S+ EF AE +T LEL E YPGDAGVLAA Sbjct 184 ALFTTWITLPQPVLGALMPRVLDGCVDYLSNTKDGEFAAEVRTALELSEVYPGDAGVLAA 243 Query 243 LLLNRISLAPGEAIFLPAGNLHAYVRGFGVEVMANSDNVLRGGLTPKHVDVPELLRVLDF 302 LLLNR++L PG+ ++L AGNLHAY+ G VE+MANSDNVLRGGLTPKHVDVPELLRVLDF Sbjct 244 LLLNRVTLEPGQGLYLDAGNLHAYLHGMAVEIMANSDNVLRGGLTPKHVDVPELLRVLDF 303 Query 303 APTPKARLRPPIRREGLGLVFETPTDEFAATLLVLDGDH-LGHEVDASSGHDGPQILLCT 361 L R G V+ TP EF + L D H +D+ +GP ILLCT Sbjct 304 DTVDIPILEAQERPGGGEFVYSTPAPEFVLARIDLSPDGPTEHRLDS----EGPHILLCT 359 Query 362 EGSATVHGKCGSLTLQRGTAAWVAADDGPIRLTAG-QPAKLFRATVG 407 GS + SL L +G A W+AA+D + TAG + A+LF A VG Sbjct 360 SGSVELRCGNDSLELSQGNAVWIAAEDPEVVATAGTECAQLFSARVG 406 >gi|229489355|ref|ZP_04383218.1| mannose-6-phosphate isomerase, class I [Rhodococcus erythropolis SK121] gi|229323452|gb|EEN89210.1| mannose-6-phosphate isomerase, class I [Rhodococcus erythropolis SK121] Length=410 Score = 439 bits (1130), Expect = 3e-121, Method: Compositional matrix adjust. Identities = 239/410 (59%), Positives = 284/410 (70%), Gaps = 10/410 (2%) Query 4 LRGALRTYAWGSRTAIAEFTGRPVPAAHPEAELWFGAHPGDPAWLQTPHGQTSLLEALVA 63 L GALR+YAWGSRTAIAE G P+ HPEAELW GAHPGDPA + T G SLLE L Sbjct 4 LEGALRSYAWGSRTAIAELRGLSTPSNHPEAELWLGAHPGDPARVITESGSESLLEVLHR 63 Query 64 DPEGQLGSASRARFGDVLPFLVKVLAADEPLSLQAHPSAEQAVEGYLREERMGIPVSSPV 123 +PE +LG + FG+ LPFL+K+LAA+EPLSLQAHPSA QA EG+ RE +G+P+ SP+ Sbjct 64 EPERELGRENLEAFGERLPFLLKLLAAEEPLSLQAHPSAVQADEGFRRENALGVPMESPI 123 Query 124 RNYRDTSHKPELLVALQPFEALAGFREAARTTELLRALAVSDLDPFIDLLSEGSDADGLR 183 RNY+D SHKPEL+VAL FEALAGFRE RT +LLRALAV +L+P+I LL D+DGLR Sbjct 124 RNYKDGSHKPELVVALSRFEALAGFREPTRTVKLLRALAVDELEPYIGLLEGQPDSDGLR 183 Query 184 ALFTTWITAPQPDIDVLVPAVLDGAIQYVSSGATEFGAEAKTVLELGERYPGDAGVLAAL 243 ALFTTWIT P + L+PAVL G I YV+ EF E +T LEL E YPGDAGVLAAL Sbjct 184 ALFTTWITLPSTVLGTLLPAVLAGCITYVAHHDAEFVTEIRTALELSEAYPGDAGVLAAL 243 Query 244 LLNRISLAPGEAIFLPAGNLHAYVRGFGVEVMANSDNVLRGGLTPKHVDVPELLRVLDFA 303 LLNR++L PG+ +FL AGNLHAY+ G VE+MANSDNVLRGGLTPKHVDVPELLRVLDF Sbjct 244 LLNRVTLEPGQGLFLAAGNLHAYLHGLAVEIMANSDNVLRGGLTPKHVDVPELLRVLDFV 303 Query 304 PTPKARLRPP-----IRREGLGLVFETPTDEFAATLLVLDGDHLGHEVDASSGHDGPQIL 358 L P + + TP EF T L D + VDAS GP+IL Sbjct 304 GADIEVLDPAPSSGSGQSGSGSYEYVTPAPEFRLTRLEFDANSTDIVVDAS----GPRIL 359 Query 359 LCTEGSATVHGKCGSLTLQRGTAAWVAADDGPIRLTAGQP-AKLFRATVG 407 +CT+G+ T +L L RG AAW+AAD+ I L+ P A++F A VG Sbjct 360 ICTDGAVTATCGTDTLDLDRGRAAWIAADEPAIHLSTRTPTAQVFSAVVG 409 >gi|111023281|ref|YP_706253.1| mannose-6-phosphate isomerase [Rhodococcus jostii RHA1] gi|110822811|gb|ABG98095.1| mannose-6-phosphate isomerase [Rhodococcus jostii RHA1] Length=410 Score = 438 bits (1126), Expect = 9e-121, Method: Compositional matrix adjust. Identities = 239/412 (59%), Positives = 292/412 (71%), Gaps = 17/412 (4%) Query 4 LRGALRTYAWGSRTAIAEFTGRPVPAAHPEAELWFGAHPGDPAWLQTPHGQTSLLEALVA 63 L GALR+YAWGSRTAIA+ G PVP AHPEAELW GAHPGDPA + T G SLL+ + + Sbjct 4 LEGALRSYAWGSRTAIAQLRGLPVPTAHPEAELWLGAHPGDPARVLTEEGPRSLLDLVHS 63 Query 64 DPEGQLGSASRARFGDVLPFLVKVLAADEPLSLQAHPSAEQAVEGYLREERMGIPVSSPV 123 +PE QLG S FGD LPFL+K+LA++EPLSLQAHPS EQA EG+ RE GIP+ S V Sbjct 64 EPERQLGKRSVETFGDRLPFLLKLLASEEPLSLQAHPSTEQAWEGFARENEAGIPLESSV 123 Query 124 RNYRDTSHKPELLVALQPFEALAGFREAARTTELLRALAVSDLDPFIDLLSEGSDADGLR 183 RNY+D SHKPEL+VAL F ALAGFR+ RT +LL A+AV +L P++ L++ D+DGLR Sbjct 124 RNYKDASHKPELVVALSRFHALAGFRDPQRTVKLLEAIAVPELQPYVGLIAGQPDSDGLR 183 Query 184 ALFTTWITAPQPDIDVLVPAVLDGAIQYVSSGAT-EFGAEAKTVLELGERYPGDAGVLAA 242 ALFTTWIT PQP + L+P VLDG + Y+S+ EF AE +T LEL E YPGDAGVLAA Sbjct 184 ALFTTWITLPQPVLGALMPRVLDGCVAYLSNTKDGEFAAEIRTALELSEVYPGDAGVLAA 243 Query 243 LLLNRISLAPGEAIFLPAGNLHAYVRGFGVEVMANSDNVLRGGLTPKHVDVPELLRVLDF 302 LLLNR++L PG+ ++L AGNLHAY+ G VE+MANSDNVLRGGLTPKHVDVPELLRVLDF Sbjct 244 LLLNRVTLEPGQGLYLDAGNLHAYLHGMAVEIMANSDNVLRGGLTPKHVDVPELLRVLDF 303 Query 303 ----APTPKARLRPPIRREGLG-LVFETPTDEFAATLLVLDGDH-LGHEVDASSGHDGPQ 356 P +A+ RP G G V+ TP EF + L D H +D+ +GP Sbjct 304 DTVDIPILEAQERP-----GSGEFVYSTPAPEFVLARIDLSPDGPTEHRLDS----EGPH 354 Query 357 ILLCTEGSATVHGKCGSLTLQRGTAAWVAADDGPIRLTAG-QPAKLFRATVG 407 ILLCT GS + +L L +G A W+AA+D + +TAG + A+LF A VG Sbjct 355 ILLCTSGSVELRCGTDALELSQGNAVWIAAEDPEVVVTAGTECAQLFSARVG 406 >gi|226305646|ref|YP_002765606.1| mannose-6-phosphate isomerase [Rhodococcus erythropolis PR4] gi|226184763|dbj|BAH32867.1| mannose-6-phosphate isomerase [Rhodococcus erythropolis PR4] Length=410 Score = 436 bits (1120), Expect = 5e-120, Method: Compositional matrix adjust. Identities = 239/415 (58%), Positives = 286/415 (69%), Gaps = 20/415 (4%) Query 4 LRGALRTYAWGSRTAIAEFTGRPVPAAHPEAELWFGAHPGDPAWLQTPHGQTSLLEALVA 63 L GALR+YAWGSRTAIAE G P+ HPEAELW GAHPGDPA + T G SLLE L Sbjct 4 LEGALRSYAWGSRTAIAELRGLATPSNHPEAELWLGAHPGDPARVITESGSESLLEVLHR 63 Query 64 DPEGQLGSASRARFGDVLPFLVKVLAADEPLSLQAHPSAEQAVEGYLREERMGIPVSSPV 123 +PE +LG + FG+ LPFL+K+LAA+EPLSLQAHPSA QA EG+ RE +G+P+ SP+ Sbjct 64 EPERELGRENLEAFGERLPFLLKLLAAEEPLSLQAHPSAVQADEGFRRENALGVPMESPI 123 Query 124 RNYRDTSHKPELLVALQPFEALAGFREAARTTELLRALAVSDLDPFIDLLSEGSDADGLR 183 RNY+D SHKPEL+VAL FEALAGFRE RT +LLRALAV +L+P+I LL D+DGLR Sbjct 124 RNYKDGSHKPELVVALSRFEALAGFREPTRTVKLLRALAVDELEPYIGLLEGQPDSDGLR 183 Query 184 ALFTTWITAPQPDIDVLVPAVLDGAIQYVSSGATEFGAEAKTVLELGERYPGDAGVLAAL 243 ALFTTWIT P + L+PAVL G I YV+ EF E +T LEL E YPGDAGVLAAL Sbjct 184 ALFTTWITLPSTVLGTLLPAVLAGCITYVAHHDAEFVTEIRTALELSEAYPGDAGVLAAL 243 Query 244 LLNRISLAPGEAIFLPAGNLHAYVRGFGVEVMANSDNVLRGGLTPKHVDVPELLRVLDF- 302 LLNR++L PG+ +FL AGNLHAY+ G VE+MANSDNVLRGGLTPKHVDVPELLRVLDF Sbjct 244 LLNRVTLEPGQGLFLAAGNLHAYLHGLAVEIMANSDNVLRGGLTPKHVDVPELLRVLDFV 303 Query 303 ---------APTPKARLRPPIRREGLGLVFETPTDEFAATLLVLDGDHLGHEVDASSGHD 353 AP+ + R E + TP EF T L D + V+A Sbjct 304 GADIEVLDPAPSSGSGQSGSGRYE-----YVTPAPEFRLTRLEFDSNATDLVVEAG---- 354 Query 354 GPQILLCTEGSATVHGKCGSLTLQRGTAAWVAADDGPIRLTAGQP-AKLFRATVG 407 GP+IL+CT+G+ T +L L RG AAW+AAD+ + LT P A++F A VG Sbjct 355 GPRILICTDGAVTATCGADTLDLDRGRAAWIAADEPVVHLTTRTPTAQVFSAVVG 409 >gi|256380312|ref|YP_003103972.1| mannose-6-phosphate isomerase, class I [Actinosynnema mirum DSM 43827] gi|255924615|gb|ACU40126.1| mannose-6-phosphate isomerase, class I [Actinosynnema mirum DSM 43827] Length=407 Score = 424 bits (1089), Expect = 2e-116, Method: Compositional matrix adjust. Identities = 241/413 (59%), Positives = 284/413 (69%), Gaps = 12/413 (2%) Query 1 VELLRGALRTYAWGSRTAIAEFTGRPVPAAHPEAELWFGAHPGDPAWLQTPHG-QTSLLE 59 +ELL A+R YAWGSRTAIAE GR VPA HPEAELW GAHPGDP+ + P G + SLL+ Sbjct 1 MELLHNAVRAYAWGSRTAIAEMLGREVPAPHPEAELWMGAHPGDPSRVIGPDGTRRSLLD 60 Query 60 ALVADPEGQLGSASRARFGDVLPFLVKVLAADEPLSLQAHPSAEQAVEGYLREERMGIPV 119 L DP GQLG+ RFG LPFL+KVLAA+EPLSLQAHPSAEQA G+ E+ G+ V Sbjct 61 LLAEDPRGQLGAGCAERFGGRLPFLLKVLAAEEPLSLQAHPSAEQAAFGFAAEDAAGLAV 120 Query 120 SSPVRNYRDTSHKPELLVALQPFEALAGFREAARTTELLRALAVSDLDPFIDLLSEGSDA 179 SP+RNY+D S KPEL+ AL F ALAGFR RT LLR+L DL P+ +LL+ D Sbjct 121 DSPIRNYKDPSAKPELICALTEFHALAGFRAPDRTVALLRSLDAPDLAPYTELLAAQPDG 180 Query 180 DGLRALFTTWITAPQPDIDVLVPAVLDGAIQYVSSGATEFGAEAKTVLELGERYPGDAGV 239 GLRALFTT IT PQ +D L+P VLD + +V EF AE +T LELGE YPGDAGV Sbjct 181 SGLRALFTTLITLPQNSLDGLLPQVLDACVAHVKDRG-EFDAECRTALELGEAYPGDAGV 239 Query 240 LAALLLNRISLAPGEAIFLPAGNLHAYVRGFGVEVMANSDNVLRGGLTPKHVDVPELLRV 299 LAALLLNRI L PGEAI+LPAGNLHAY+ G GVE++ANSDNVLR GLTPKHVDVPEL+RV Sbjct 240 LAALLLNRIVLRPGEAIYLPAGNLHAYLHGTGVEILANSDNVLRCGLTPKHVDVPELMRV 299 Query 300 LDFAPTPKARLRPPIRREGLGLVFETPTDEFAATLLVLDGDHLGHEVDASSGHDGPQILL 359 LDF+ R R GL V+ TP EF + + L G V+ H GPQI+L Sbjct 300 LDFSSGDMPVQRGEPTRPGL-WVYRTPCPEFELSRIELAA---GESVEVD--HGGPQIVL 353 Query 360 CTEGSAT--VH--GKCGSLTLQRGTAAWVAADDGPIRLTAGQPAKLFRATVGL 408 C EGSAT VH G L L+RG + W+ A D +R+ A + A+LFRAT G+ Sbjct 354 CAEGSATLSVHRGGHADVLELRRGQSVWLPAADPALRVEATEDAQLFRATPGV 406 >gi|343926913|ref|ZP_08766406.1| mannose-6-phosphate isomerase [Gordonia alkanivorans NBRC 16433] gi|343763273|dbj|GAA13332.1| mannose-6-phosphate isomerase [Gordonia alkanivorans NBRC 16433] Length=425 Score = 417 bits (1072), Expect = 1e-114, Method: Compositional matrix adjust. Identities = 223/402 (56%), Positives = 278/402 (70%), Gaps = 3/402 (0%) Query 8 LRTYAWGSRTAIAEFTGRPVPAAHPEAELWFGAHPGDPAWLQTPHG-QTSLLEALVADPE 66 +R YAWGSRTAIA GRPVP+AHPEAELWFG+HP A P G + L+E + ADP Sbjct 2 VRPYAWGSRTAIASIQGRPVPSAHPEAELWFGSHPAGSARCVDPSGPEQHLVEVIDADPV 61 Query 67 GQLGSASRARFGDVLPFLVKVLAADEPLSLQAHPSAEQAVEGYLREERMGIPVSSPVRNY 126 LG+AS A FG+ LPFL+K+LAA+E LSLQAHPSA+QA EG+ RE G+ + + RNY Sbjct 62 ATLGAASAAEFGNRLPFLLKILAAEEALSLQAHPSADQAREGFERENARGLALDARDRNY 121 Query 127 RDTSHKPELLVALQPFEALAGFREAARTTELLRALAVSDLDPFIDLLSEGSDADGLRALF 186 RD HKPEL+VA PF+ALAGFR+ +T LLR L VS+LD ++ +L+ D++GLRA+F Sbjct 122 RDPWHKPELIVATTPFDALAGFRDPHKTVALLRELQVSELDHYLGMLAGQPDSEGLRAVF 181 Query 187 TTWITAPQPDIDVLVPAVLDGAIQYVSSGATEFGAEAKTVLELGERYPGDAGVLAALLLN 246 TTW+T P+ I LVPAVL GAI+ +S+G TEF AE +TV ELGE YP D GVLA+LLLN Sbjct 182 TTWLTLPESSIRQLVPAVLHGAIEVLSAGRTEFSAELRTVCELGEDYPNDPGVLASLLLN 241 Query 247 RISLAPGEAIFLPAGNLHAYVRGFGVEVMANSDNVLRGGLTPKHVDVPELLRVLDFAPTP 306 + L PG+ ++LPAGNLHAY+RG GVE+MANSDNVLRGGLTPKH+DVPELLRVLDF P Sbjct 242 HVHLEPGQGLYLPAGNLHAYLRGTGVEIMANSDNVLRGGLTPKHIDVPELLRVLDFTPVD 301 Query 307 KARLRPPIRREGLGLVFETPTDEFAATLLVLDGDHLGHEVDASSGHDGPQILLCTEGSAT 366 A++ PP+R G V+ TP EF + + LDG L H GPQIL G+ Sbjct 302 AAQMAPPVRMIGAERVYLTPAPEFRLSRIELDGTGLHHSSSICFDMPGPQILAVLSGAVE 361 Query 367 VH-GKCGSLTLQRGTAAWVAADDGPIRLTAGQP-AKLFRATV 406 V G LT++ G A W+ DD + + A A +RA V Sbjct 362 VRPGDGAPLTVKSGHALWITDDDPDVIVRAASARAVFYRALV 403 >gi|262203186|ref|YP_003274394.1| mannose-6-phosphate isomerase, class I [Gordonia bronchialis DSM 43247] gi|262086533|gb|ACY22501.1| mannose-6-phosphate isomerase, class I [Gordonia bronchialis DSM 43247] Length=416 Score = 413 bits (1062), Expect = 3e-113, Method: Compositional matrix adjust. Identities = 225/407 (56%), Positives = 277/407 (69%), Gaps = 4/407 (0%) Query 4 LRGALRTYAWGSRTAIAEFTGRPVPAAHPEAELWFGAHPGDPAWLQTPHG--QTSLLEAL 61 L G +R YAWGSR AIA GRPVP+AHPEAELWFG+HP PA G T LL A+ Sbjct 4 LEGVVRPYAWGSRVAIAAMQGRPVPSAHPEAELWFGSHPAGPARCVGADGAPHTDLLTAI 63 Query 62 VADPEGQLGSASRARFGDVLPFLVKVLAADEPLSLQAHPSAEQAVEGYLREERMGIPVSS 121 ADP LGS+S + FG+ LPFL+KVLAADEPLSLQAHPS+ QA EG+ RE G+ + + Sbjct 64 DADPVDALGSSSVSAFGNRLPFLLKVLAADEPLSLQAHPSSAQAREGFERENAQGLALDA 123 Query 122 PVRNYRDTSHKPELLVALQPFEALAGFREAARTTELLRALAVSDLDPFIDLLSEGSDADG 181 RNYRD HKPEL+VA+ PF+ALAGFR T LLR L VS+LDP++ +L D++G Sbjct 124 RDRNYRDPWHKPELIVAITPFDALAGFRNPHETVRLLRELQVSELDPYLGMLVGQPDSEG 183 Query 182 LRALFTTWITAPQPDIDVLVPAVLDGAIQYVSSGATEFGAEAKTVLELGERYPGDAGVLA 241 LRALFTTW+T P+ I +LVPAVL GA++ + + +++F AE +TVLELGE YP D GVLA Sbjct 184 LRALFTTWLTLPESAIKLLVPAVLAGAVEQLGTRSSDFAAELRTVLELGEAYPLDPGVLA 243 Query 242 ALLLNRISLAPGEAIFLPAGNLHAYVRGFGVEVMANSDNVLRGGLTPKHVDVPELLRVLD 301 +LLLNR+ L PGE I+LPAGNLHAY+ G GVE+MANSDNVLRGGLTPKH+DVPELLRVLD Sbjct 244 SLLLNRLHLEPGEGIYLPAGNLHAYLSGTGVEIMANSDNVLRGGLTPKHIDVPELLRVLD 303 Query 302 FAPTPKARLRPPIRREGLGLVFETPTDEFAATLLVLDGDHLGHEVDASSGHDGPQILLCT 361 F P L PIR G ++ TP EF + + LDG L + GPQIL Sbjct 304 FTPVEPDELVVPIRTIGAERIYLTPAPEFRLSRVELDGTGLLYASSICFDMPGPQILAVL 363 Query 362 EGSATVHGKCGS-LTLQRGTAAWVAADDGPIRLTAGQP-AKLFRATV 406 G+ V G+ +++ G AAW+A D + + A A FRA V Sbjct 364 SGAVEVRSPSGTVMSVTAGQAAWIADSDHDVVVRAASSRAVFFRALV 410 >gi|257057069|ref|YP_003134901.1| mannose-6-phosphate isomerase [Saccharomonospora viridis DSM 43017] gi|256586941|gb|ACU98074.1| mannose-6-phosphate isomerase [Saccharomonospora viridis DSM 43017] Length=411 Score = 399 bits (1025), Expect = 5e-109, Method: Compositional matrix adjust. Identities = 222/417 (54%), Positives = 279/417 (67%), Gaps = 19/417 (4%) Query 1 VELLRGALRTYAWGSRTAIAEFTGRPVPAAHPEAELWFGAHPGDPAWLQTPHG-QTSLLE 59 +ELLR A+R YAWGSRT I E GRPVPA HPEAELW GAHPGDP+ + G +TSLLE Sbjct 1 MELLRNAVRPYAWGSRTTIPELLGRPVPAPHPEAELWMGAHPGDPSHVIAQDGTETSLLE 60 Query 60 ALVADPEGQLGSASRARFGDVLPFLVKVLAADEPLSLQAHPSAEQAVEGYLREERMGIPV 119 + +DP GQLG R+G LPFL+K+LA +EPLS+QAHPSAEQA EG+ REE GIP Sbjct 61 LVDSDPIGQLGEECANRWGGRLPFLLKILAIEEPLSMQAHPSAEQAAEGWAREEAAGIPK 120 Query 120 SSPVRNYRDTSHKPELLVALQPFEALAGFREAARTTELLRALAVSDLDPFIDLLSEGSDA 179 +P RNY D + KPEL+ AL F ALAGFR+ RT +LLRA+ L + +LL+ D+ Sbjct 121 DAPNRNYPDPTAKPELVCALTEFHALAGFRDPKRTVQLLRAIDTPGLTKYTELLAAQPDS 180 Query 180 DGLRALFTTWITAPQPDIDVLVPAVLDGAIQYVSSGATEFGAEAKTVLELGERYPGDAGV 239 DGLRALFTTWIT PQP +D L+P VLD ++++ EF E +TVLELGE +P DAGV Sbjct 181 DGLRALFTTWITMPQPTLDQLLPEVLDACVRHIKEDG-EFDLECRTVLELGEAHPHDAGV 239 Query 240 LAALLLNRISLAPGEAIFLPAGNLHAYVRGFGVEVMANSDNVLRGGLTPKHVDVPELLRV 299 LAA+LLNR++L+ GEAI+LPAGNLH Y+ G VE++ANSDN+LRGGLTPKHVDVPELLRV Sbjct 240 LAAMLLNRLTLSAGEAIYLPAGNLHLYLHGTAVEILANSDNILRGGLTPKHVDVPELLRV 299 Query 300 LDFAPTPKARLRPPIRREGLGLV------FETPTDEFAATLLVLDGDHLGHEVDASSGHD 353 +DFA P+ G V + T EF + + G G + Sbjct 300 VDFACGDM-----PVLCGEFGDVDERMAFYRTDAPEFELSRVEWSG---GDRGEVRLPRS 351 Query 354 GPQILLCTEGSATVHGKCGS-LTLQRGTAAWVAADDGPIRL--TAGQPAKLFRATVG 407 GP+ILLCTEG + + G+ + L+RG + W+ A D +R+ PA +FRAT G Sbjct 352 GPEILLCTEGELLLCSEDGTKIELRRGESVWLPASDPEVRIRPVGSGPAHVFRATPG 408 >gi|291008025|ref|ZP_06565998.1| mannose-6-phosphate isomerase [Saccharopolyspora erythraea NRRL 2338] Length=412 Score = 397 bits (1020), Expect = 2e-108, Method: Compositional matrix adjust. Identities = 233/418 (56%), Positives = 279/418 (67%), Gaps = 17/418 (4%) Query 1 VELLRGALRTYAWGSRTAIAEFTGRPVPAAHPEAELWFGAHPGDPAWLQTPHG-QTSLLE 59 +ELLR A+R YAWGSRTAIA+ GRPVP HPEAELW GAHPGDP+ L G + SLL Sbjct 1 MELLRNAVRPYAWGSRTAIADLLGRPVPTPHPEAELWMGAHPGDPSMLVRHDGTEESLLA 60 Query 60 ALVADPEGQLGSASRARFGDVLPFLVKVLAADEPLSLQAHPSAEQAVEGYLREERMGIPV 119 L ADP LG+ R+G LPFL KVLAADEPLSLQAHPS EQA EG+ REE GIP Sbjct 61 LLDADPAHHLGAGCNDRWGGRLPFLFKVLAADEPLSLQAHPSVEQAAEGFAREEAAGIPR 120 Query 120 SSPVRNYRDTSHKPELLVALQPFEALAGFREAARTTELLRALAVSDLDPFIDLLSEGSDA 179 ++ RNY D + KPEL+ AL F ALAGFREA RT LL AL V L LL+ DA Sbjct 121 NAANRNYPDPTAKPELICALTEFHALAGFREACRTVRLLDALDVPSLRAHRGLLAAQPDA 180 Query 180 DGLRALFTTWITAPQPDIDVLVPAVLDGAIQYVSSGATEFGAEAKTVLELGERYPGDAGV 239 DGLRALFTTWIT P+ + + P +LD +++V EF E +TVLELGE YP DAGV Sbjct 181 DGLRALFTTWITLPEHYLRDVTPELLDACVEHVRERG-EFALECRTVLELGEAYPNDAGV 239 Query 240 LAALLLNRISLAPGEAIFLPAGNLHAYVRGFGVEVMANSDNVLRGGLTPKHVDVPELLRV 299 LA+LLLNR+ L PGEAIFLPAGNLHAY+ G GVE++ANSDN+LR GLTPKHVDVPELLRV Sbjct 240 LASLLLNRLVLQPGEAIFLPAGNLHAYLHGTGVEILANSDNILRCGLTPKHVDVPELLRV 299 Query 300 LDFAPTPKARLRPPIRREGLGLVFETPTDEFAATLLVLD-GDHLGHEVDASSGHDGPQIL 358 LDFA L+ L V++TP +EF + + D G +D++ GPQI+ Sbjct 300 LDFACGDMRILKGESLDANL-TVYKTPAEEFELSRVDWTLADSGGVLLDSA----GPQIV 354 Query 359 LCTEGS---ATVHGKCGSLTLQRGTAAWVAADDG-----PIRLTAGQPAKLFRATVGL 408 LCT+G +TV G S+ L+RG + W+AA D P L A A++FRA G+ Sbjct 355 LCTKGRVHLSTVDGS-RSVELERGESVWLAASDEAAVARPATLDADGAAQVFRAAAGV 411 >gi|111022402|ref|YP_705374.1| mannose-6-phosphate isomerase [Rhodococcus jostii RHA1] gi|110821932|gb|ABG97216.1| mannose-6-phosphate isomerase [Rhodococcus jostii RHA1] Length=435 Score = 397 bits (1019), Expect = 3e-108, Method: Compositional matrix adjust. Identities = 220/415 (54%), Positives = 276/415 (67%), Gaps = 17/415 (4%) Query 1 VELLRGALRTYAWGSRTAIAEFTGRPVPAAHPEAELWFGAHPGDPAWLQTPHGQTSLLEA 60 ++ L G +R+YAWGS T +AE TGRP P+ PEAELW GAHP DPA + SLL+ Sbjct 1 MKRLHGVIRSYAWGSHTVLAELTGRPSPSDRPEAELWLGAHPADPAHVDDAVSGVSLLDV 60 Query 61 LVADPEGQLGSASRARFGDVLPFLVKVLAADEPLSLQAHPSAEQAVEGYLREERMGIPVS 120 + ADP GQLG+A+ RF LPFL+KVLAADEPLSLQAHP+A QA EG+ RE G+P+ Sbjct 61 ISADPLGQLGAANAERFRGRLPFLLKVLAADEPLSLQAHPNAVQAREGFERENASGVPLD 120 Query 121 SPVRNYRDTSHKPELLVALQPFEALAGFREAARTTELLRALAVSDLDPFIDLLSEGSDAD 180 SP RNY+D +HKPEL+VAL FEALAGFR+ RT LLRAL V++L+ + L +++ Sbjct 121 SPARNYKDDNHKPELVVALTKFEALAGFRDVRRTVALLRALGVAELNRCAEQLEAQTNSS 180 Query 181 GLRALFTTWITAPQPDIDVLVPAVLDGAIQYVSSGAT----EFGAEAKTVLELGERYPGD 236 G+RALFT WIT + L+ V++G +Y+S+ + EF AEA+T LELG RYP D Sbjct 181 GIRALFTQWITGDRHPA-TLIGGVVEGCRRYLSTMSDGADGEFAAEAQTALELGSRYPND 239 Query 237 AGVLAALLLNRISLAPGEAIFLPAGNLHAYVRGFGVEVMANSDNVLRGGLTPKHVDVPEL 296 GVL +LLLNRI+L PGE +FL AGNLHAY+RG VE+MANSDNVLRGGLTPKHVDVPEL Sbjct 240 PGVLISLLLNRITLEPGEGLFLAAGNLHAYLRGAAVEIMANSDNVLRGGLTPKHVDVPEL 299 Query 297 LRVLDFAPTPKARL-----RPPIRREGLGLVFETPTDEFAATLLVLDGDH-LGHEVDASS 350 L VLDF P P L P +RR ++ TP EF T L LD G A+ Sbjct 300 LNVLDFRPAPMPVLGADGVDPDLRR-----LYRTPEAEFELTRLKLDTSRDDGSSSAATL 354 Query 351 GHDGPQILLCTEGSATVHGKCGSLTLQRGTAAWVAADDGPIRLT-AGQPAKLFRA 404 P+I+LCT GS + +C SL L G +AW+ A + + L A Q A++F A Sbjct 355 AAGDPRIVLCTAGSTVLSSQCDSLELSAGQSAWLPASNPAVTLAPAQQRAQVFVA 409 >gi|302530040|ref|ZP_07282382.1| mannose-6-phosphate isomerase, class I [Streptomyces sp. AA4] gi|302438935|gb|EFL10751.1| mannose-6-phosphate isomerase, class I [Streptomyces sp. AA4] Length=407 Score = 390 bits (1002), Expect = 2e-106, Method: Compositional matrix adjust. Identities = 221/412 (54%), Positives = 276/412 (67%), Gaps = 17/412 (4%) Query 4 LRGALRTYAWGSRTAIAEFTGRPVPAAHPEAELWFGAHPGDPAWLQTPHG-QTSLLEALV 62 +R A+R YAWGSRTAI + GRPVPA HPEAELW GAHPGDP+ + P G + SLLE + Sbjct 1 MRNAVRPYAWGSRTAIPQLQGRPVPAPHPEAELWMGAHPGDPSHVLGPDGAEVSLLELVD 60 Query 63 ADPEGQLGSASRARFGDVLPFLVKVLAADEPLSLQAHPSAEQAVEGYLREERMGIPVSSP 122 ADP GQLG R+G+ LPFL+K+LAA+EPLS+QAHPSA QA EG+ REE++GIP + Sbjct 61 ADPVGQLGEDCARRWGNRLPFLLKILAAEEPLSMQAHPSAAQAAEGHAREEKLGIPRDAA 120 Query 123 VRNYRDTSHKPELLVALQPFEALAGFREAARTTELLRALAVSDLDPFIDLLSEGSDADGL 182 RNY D + KPEL+ AL F ALAGFR+ RT +LL+A+ L + LL D GL Sbjct 121 NRNYPDPTAKPELVCALTEFHALAGFRDPNRTVKLLKAIETPGLGKYTGLLEAQPDPAGL 180 Query 183 RALFTTWITAPQPDIDVLVPAVLDGAIQYVSSGATEFGAEAKTVLELGERYPGDAGVLAA 242 RALFTTWIT PQ +D L+P VLD +++V EF E +T+LELGE +P DAGVLAA Sbjct 181 RALFTTWITLPQSALDELLPEVLDACVRHVQDHG-EFATECRTILELGETHPRDAGVLAA 239 Query 243 LLLNRISLAPGEAIFLPAGNLHAYVRGFGVEVMANSDNVLRGGLTPKHVDVPELLRVLDF 302 LLLNR++L GEAI+LPAGNLH Y+ G VE++ANSDN+LR GLTPKHVDVPELLRV+DF Sbjct 240 LLLNRLTLRAGEAIYLPAGNLHLYLHGTAVEILANSDNILRCGLTPKHVDVPELLRVVDF 299 Query 303 APTPKARLRPPIRREGLG---LVFETPTDEFAATLLVL-DGDHLGHEVDASSGHDGPQIL 358 A P E G V+ T EF + + G+ EVD++ GPQIL Sbjct 300 A----CGEMPVQHGECAGQRMAVYHTDAPEFELSRMEWAAGEDAEIEVDSA----GPQIL 351 Query 359 LCTEGSATVHGKCG-SLTLQRGTAAWVAADDGPIRLT--AGQPAKLFRATVG 407 LCTEG V G + L+RG + W+ A D +R+ G+ ++LFRAT G Sbjct 352 LCTEGDLLVRASDGEQVELRRGQSVWLPAADPAVRVRPLGGEKSQLFRATAG 403 >gi|325000904|ref|ZP_08122016.1| mannose-6-phosphate isomerase ManA [Pseudonocardia sp. P1] Length=404 Score = 390 bits (1001), Expect = 3e-106, Method: Compositional matrix adjust. Identities = 224/398 (57%), Positives = 272/398 (69%), Gaps = 7/398 (1%) Query 1 VELLRGALRTYAWGSRTAIAEFTGRPVPAAHPEAELWFGAHPGDPAWLQTPHGQTSLLEA 60 +ELL +RTYAWGSRT IAE G+PVPA HP+AELW GAHP P+ +++ L E Sbjct 1 MELLENPIRTYAWGSRTVIAELLGQPVPAPHPQAELWLGAHPAAPSKVRSGDAVRPLHEL 60 Query 61 LVADPEGQLGSASRARFGDVLPFLVKVLAADEPLSLQAHPSAEQAVEGYLREERMGIPVS 120 + ADP LG R R+ LPFL+K+LAADEPLSLQAHPS EQA +G+ RE G+PV Sbjct 61 IAADPAAALGP-GRGRWEGRLPFLLKLLAADEPLSLQAHPSLEQARDGWARENAAGLPVD 119 Query 121 SPVRNYRDTSHKPELLVALQPFEALAGFREAARTTELLRALAVSDLDPFIDLLSEGSDAD 180 +P RNYRD +HKPEL+ AL F AL GFRE A T LLRAL V +L + +LL+ + D Sbjct 120 APDRNYRDANHKPELICALTDFVALVGFREPASTVALLRALDVPELASYAELLAGQPNPD 179 Query 181 GLRALFTTWITAPQPDIDVLVPAVLDGAIQYVSSGATEFGAEAKTVLELGERYPGDAGVL 240 GLRALFTTWIT PQ +D LVPA+ GA++ + GA E+ EAKTVL+L ERYPGDAGVL Sbjct 180 GLRALFTTWITLPQSLLDGLVPALQGGAVRLLERGAGEWTGEAKTVLDLSERYPGDAGVL 239 Query 241 AALLLNRISLAPGEAIFLPAGNLHAYVRGFGVEVMANSDNVLRGGLTPKHVDVPELLRVL 300 AALLLNR +LAPGEA++LPAGNLHAY+ G G+E+MANSDNVLRGGLTPKHVDVPELLRVL Sbjct 240 AALLLNRTTLAPGEALYLPAGNLHAYLSGAGIELMANSDNVLRGGLTPKHVDVPELLRVL 299 Query 301 DFAPTPKARLRPPIRREGLGL-VFETPTDEFAATLLVLDGDHLGHEVDASSGHDGPQILL 359 DFA P A RP R+ G ++ P +EF L+ D G + G G +I+L Sbjct 300 DFAAPPPAVRRPAPERDADGWHRYDVPVEEF----LLRRADTGGRDKLDVPG-TGARIML 354 Query 360 CTEGSATVHGKCGSLTLQRGTAAWVAADDGPIRLTAGQ 397 CT G A V + L RG A +++A D LT G Sbjct 355 CTSGDAAVEAGGAEIELPRGAAVYLSAGDTGAVLTTGD 392 >gi|300789827|ref|YP_003770118.1| mannose-6-phosphate isomerase [Amycolatopsis mediterranei U32] gi|299799341|gb|ADJ49716.1| mannose-6-phosphate isomerase [Amycolatopsis mediterranei U32] gi|340531495|gb|AEK46700.1| mannose-6-phosphate isomerase [Amycolatopsis mediterranei S699] Length=409 Score = 388 bits (997), Expect = 7e-106, Method: Compositional matrix adjust. Identities = 222/414 (54%), Positives = 274/414 (67%), Gaps = 16/414 (3%) Query 1 VELLRGALRTYAWGSRTAIAEFTGRPVPAAHPEAELWFGAHPGDPAWLQTPHG-QTSLLE 59 +ELLR A+R YAWGSRTAI E GRPVPA HPEAELW GAHPGDP+ + P G + SLL Sbjct 1 MELLRNAVRPYAWGSRTAIPELLGRPVPAPHPEAELWMGAHPGDPSHVIGPDGTERSLLG 60 Query 60 ALVADPEGQLGSASRARFGDVLPFLVKVLAADEPLSLQAHPSAEQAVEGYLREERMGIPV 119 + ADP QLG R+G LPFL+K+LAA+EPLS+QAHPSA QA EG+ REER+GIP Sbjct 61 LVDADPVAQLGERCAKRWGGRLPFLLKILAAEEPLSMQAHPSAAQAAEGHAREERLGIPR 120 Query 120 SSPVRNYRDTSHKPELLVALQPFEALAGFREAARTTELLRALAVSDLDPFIDLLSEGSDA 179 + RNY D + KPEL+ AL F ALAGFR RT +LL+A+ L + LL D Sbjct 121 DAANRNYPDPTAKPELVCALTEFHALAGFRAPDRTMKLLKAIETPGLANYTGLLEAQPDP 180 Query 180 DGLRALFTTWITAPQPDIDVLVPAVLDGAIQYVSSGATEFGAEAKTVLELGERYPGDAGV 239 GLRALFTTWIT PQ +D L+P VLD +++V EF E +T+LELGE +P DAGV Sbjct 181 SGLRALFTTWITLPQSSLDRLLPEVLDACVRHVQEHG-EFAVECRTILELGEAHPRDAGV 239 Query 240 LAALLLNRISLAPGEAIFLPAGNLHAYVRGFGVEVMANSDNVLRGGLTPKHVDVPELLRV 299 LAALLLNR++L GEAI+LPAGNLH Y+ G VE++ANSDN+LR GLTPKHVDVPELLRV Sbjct 240 LAALLLNRLTLRAGEAIYLPAGNLHLYLHGTAVEILANSDNILRCGLTPKHVDVPELLRV 299 Query 300 LDFAPTPKARLRPPIR---REGLGLVFETPTDEFAATLLVLDGDHLGHEVDASSGHDGPQ 356 +DFA P++ G V+ T EF + + G + + + GPQ Sbjct 300 VDFACGEM-----PVQCGDSGGRMAVYRTDAPEFELSRVEWAA---GQDDEIAVDSVGPQ 351 Query 357 ILLCTEGSATVHGKCG-SLTLQRGTAAWVAADDGPIRLTA--GQPAKLFRATVG 407 ILLCT G V G + L+RG + W+ A D P+R+ A G+ A+LFRAT G Sbjct 352 ILLCTAGDLLVTADDGEKVELRRGQSVWLPAADPPVRVRALGGERAQLFRATAG 405 >gi|134102890|ref|YP_001108551.1| mannose-6-phosphate isomerase [Saccharopolyspora erythraea NRRL 2338] gi|133915513|emb|CAM05626.1| mannose-6-phosphate isomerase [Saccharopolyspora erythraea NRRL 2338] Length=405 Score = 388 bits (997), Expect = 9e-106, Method: Compositional matrix adjust. Identities = 228/411 (56%), Positives = 273/411 (67%), Gaps = 17/411 (4%) Query 8 LRTYAWGSRTAIAEFTGRPVPAAHPEAELWFGAHPGDPAWLQTPHG-QTSLLEALVADPE 66 +R YAWGSRTAIA+ GRPVP HPEAELW GAHPGDP+ L G + SLL L ADP Sbjct 1 MRPYAWGSRTAIADLLGRPVPTPHPEAELWMGAHPGDPSMLVRHDGTEESLLALLDADPA 60 Query 67 GQLGSASRARFGDVLPFLVKVLAADEPLSLQAHPSAEQAVEGYLREERMGIPVSSPVRNY 126 LG+ R+G LPFL KVLAADEPLSLQAHPS EQA EG+ REE GIP ++ RNY Sbjct 61 HHLGAGCNDRWGGRLPFLFKVLAADEPLSLQAHPSVEQAAEGFAREEAAGIPRNAANRNY 120 Query 127 RDTSHKPELLVALQPFEALAGFREAARTTELLRALAVSDLDPFIDLLSEGSDADGLRALF 186 D + KPEL+ AL F ALAGFREA RT LL AL V L LL+ DADGLRALF Sbjct 121 PDPTAKPELICALTEFHALAGFREACRTVRLLDALDVPSLRAHRGLLAAQPDADGLRALF 180 Query 187 TTWITAPQPDIDVLVPAVLDGAIQYVSSGATEFGAEAKTVLELGERYPGDAGVLAALLLN 246 TTWIT P+ + + P +LD +++V EF E +TVLELGE YP DAGVLA+LLLN Sbjct 181 TTWITLPEHYLRDVTPELLDACVEHVRERG-EFALECRTVLELGEAYPNDAGVLASLLLN 239 Query 247 RISLAPGEAIFLPAGNLHAYVRGFGVEVMANSDNVLRGGLTPKHVDVPELLRVLDFAPTP 306 R+ L PGEAIFLPAGNLHAY+ G GVE++ANSDN+LR GLTPKHVDVPELLRVLDFA Sbjct 240 RLVLQPGEAIFLPAGNLHAYLHGTGVEILANSDNILRCGLTPKHVDVPELLRVLDFACGD 299 Query 307 KARLRPPIRREGLGLVFETPTDEFAATLLVLD-GDHLGHEVDASSGHDGPQILLCTEGS- 364 L+ L V++TP +EF + + D G +D++ GPQI+LCT+G Sbjct 300 MRILKGESLDANL-TVYKTPAEEFELSRVDWTLADSGGVLLDSA----GPQIVLCTKGRV 354 Query 365 --ATVHGKCGSLTLQRGTAAWVAADDG-----PIRLTAGQPAKLFRATVGL 408 +TV G S+ L+RG + W+AA D P L A A++FRA G+ Sbjct 355 HLSTVDGS-RSVELERGESVWLAASDEAAVARPATLDADGAAQVFRAAAGV 404 >gi|331698949|ref|YP_004335188.1| mannose-6-phosphate isomerase, class I [Pseudonocardia dioxanivorans CB1190] gi|326953638|gb|AEA27335.1| mannose-6-phosphate isomerase, class I [Pseudonocardia dioxanivorans CB1190] Length=405 Score = 384 bits (986), Expect = 2e-104, Method: Compositional matrix adjust. Identities = 225/413 (55%), Positives = 271/413 (66%), Gaps = 15/413 (3%) Query 1 VELLRGALRTYAWGSRTAIAEFTGRPVPAAHPEAELWFGAHPGDPAWL-QTPHGQTSLLE 59 +ELL +R YAWGSRT IAE GRP P+ HP+AELW GAHP DP+ + + SL+E Sbjct 1 MELLENPVRPYAWGSRTVIAELLGRPSPSPHPQAELWLGAHPADPSHVVRDDVTAESLIE 60 Query 60 ALVADPEGQLGSASRARFGDVLPFLVKVLAADEPLSLQAHPSAEQAVEGYLREERMGIPV 119 + ADP LG R+ LPFL+KVLAADEPLSLQAHPSAEQA G+ RE MG+P Sbjct 61 LIDADPVRALGPDRVDRWSGRLPFLLKVLAADEPLSLQAHPSAEQAAAGFERENAMGLPA 120 Query 120 SSPVRNYRDTSHKPELLVALQPFEALAGFREAARTTELLRALAVSDLDPFIDLLSEGSDA 179 +P RNYRD +HKPEL+ AL F AL GFREA + LLRAL V L + +LL+ Sbjct 121 DAPDRNYRDPNHKPELICALTEFHALVGFREADASVRLLRALDVPALAAYTELLAAQLGP 180 Query 180 DGLRALFTTWITAPQPDIDVLVPAVLDGAIQYVSSGATEFGAEAKTVLELGERYPGDAGV 239 DGLRALFTTWIT PQ +D LVPAV +GA++ + G E+ EA+T+LEL ERYPGDAGV Sbjct 181 DGLRALFTTWITLPQSVLDDLVPAVQEGAVRLAAVGG-EWCMEARTILELSERYPGDAGV 239 Query 240 LAALLLNRISLAPGEAIFLPAGNLHAYVRGFGVEVMANSDNVLRGGLTPKHVDVPELLRV 299 LA++LLNR L PGEA+ LPAGNLHAY+ G G+EVMANSDNVLRGGLTPKHVDVPELLRV Sbjct 240 LASILLNRTVLQPGEALHLPAGNLHAYLSGAGMEVMANSDNVLRGGLTPKHVDVPELLRV 299 Query 300 LDFAPTPKARLRPPI---RREGLGLVFETPTDEFAATLLVLDGDHLGHEVDASSGHDGPQ 356 LDFA P PPI + + ++TP EF V +G V GP+ Sbjct 300 LDFAAAP-----PPICTGHPDRGWIRYDTPAVEFCLRRFVAEGPQASVVVP----DGGPR 350 Query 357 ILLCTEGSATVHGKCGSLTLQRGTAAWVA-ADDGPIRLTAGQPAKLFRATVGL 408 IL CT GSA + G L L GT+ ++ AD G + +A +LF A GL Sbjct 351 ILACTSGSAIIRSDSGVLKLAPGTSVFLPDADAGVVVDSAAPGTQLFLAGDGL 403 >gi|326381473|ref|ZP_08203167.1| mannose-6-phosphate isomerase [Gordonia neofelifaecis NRRL B-59395] gi|326199720|gb|EGD56900.1| mannose-6-phosphate isomerase [Gordonia neofelifaecis NRRL B-59395] Length=415 Score = 379 bits (973), Expect = 5e-103, Method: Compositional matrix adjust. Identities = 217/410 (53%), Positives = 269/410 (66%), Gaps = 4/410 (0%) Query 1 VELLRGALRTYAWGSRTAIAEFTGRPVPAAHPEAELWFGAHPGDPA-WLQTPHGQTSLLE 59 ++LL G +R YAWGSRTA+AE G P P+ HPEAELWFGAHP PA L G LL Sbjct 1 MKLLAGVVRPYAWGSRTALAELRGTPSPSTHPEAELWFGAHPASPAKILGEIGGPEDLLA 60 Query 60 ALVADPEGQLGSASRARFGDVLPFLVKVLAADEPLSLQAHPSAEQAVEGYLREERMGIPV 119 A+ ADPE +LG++ FG LP+L+K+LAA EPLSLQAHPS +QA+ G+ RE G+ + Sbjct 61 AIEADPEHELGASITDEFGPRLPYLLKILAAQEPLSLQAHPSLDQAIAGFERENAAGLAM 120 Query 120 SSPVRNYRDTSHKPELLVALQPFEALAGFREAARTTELLRALAVSDLDPFIDLLSEGSDA 179 +P RNYRD SHKPEL+VAL F+ALAGFR+ +T EL+ LAV L P++ +L E D Sbjct 121 DAPDRNYRDPSHKPELVVALTEFDALAGFRDPHQTVELMELLAVPGLAPYLGMLVEQPDE 180 Query 180 DGLRALFTTWITAPQPDIDVLVPAVLDGAIQYVSSGATEFGAEAKTVLELGERYPGDAGV 239 GLRA+FTTW+T P I LVP VL GAI+ + S F E +++LELGE YPGD GV Sbjct 181 TGLRAVFTTWLTLPDSVIGALVPDVLAGAIRVLGSADQRFRLELRSLLELGEAYPGDPGV 240 Query 240 LAALLLNRISLAPGEAIFLPAGNLHAYVRGFGVEVMANSDNVLRGGLTPKHVDVPELLRV 299 LA++LLNRI L PGE I+L AGNLHAY+ G VE+MANSDNVLRGGLTPKH+DVPELLRV Sbjct 241 LASMLLNRIRLQPGEGIYLSAGNLHAYLHGTAVELMANSDNVLRGGLTPKHIDVPELLRV 300 Query 300 LDFAPTPKARLRPPIRREGLGLVFETPTDEFAATLLVLDGDHLGHEVDASSGHDGPQILL 359 LDF P L+P +R G ++ TP EF + + LDG + S GPQIL Sbjct 301 LDFRPVTVEALKPDVRSLGAERIYLTPAPEFRLSRIELDGTGVHAAQSISLDVTGPQILA 360 Query 360 CTEGSATVHGKCGSLTLQR--GTAAWVAADDGPIRLTA-GQPAKLFRATV 406 G V G G L+ G A W++A D + + A A +FRA V Sbjct 361 VISGRVAVEGTGGGEHLKAGPGDAVWLSAADPDVVVRAVSSNAVVFRAIV 410 >gi|312140684|ref|YP_004008020.1| mannose-6-phosphate isomerase mana [Rhodococcus equi 103S] gi|311890023|emb|CBH49341.1| mannose-6-phosphate isomerase ManA [Rhodococcus equi 103S] Length=365 Score = 373 bits (957), Expect = 3e-101, Method: Compositional matrix adjust. Identities = 208/360 (58%), Positives = 249/360 (70%), Gaps = 6/360 (1%) Query 53 GQTSLLEALVADPEGQLGSASRARFGDVLPFLVKVLAADEPLSLQAHPSAEQAVEGYLRE 112 G SL + + A P +LG S A+FG+ LPFL+KVLAA+EPLSLQAHPSAEQA EG+ RE Sbjct 6 GTRSLRDVIDAAPLSELGERSVAQFGERLPFLLKVLAAEEPLSLQAHPSAEQAREGFARE 65 Query 113 ERMGIPVSSPVRNYRDTSHKPELLVALQPFEALAGFREAARTTELLRALAVSDLDPFIDL 172 + +GIPV S RNYRD SHKPEL+VAL FEALAGFR+ RT L+AL V L P++ L Sbjct 66 DAVGIPVDSAERNYRDASHKPELVVALTRFEALAGFRDPHRTVRFLQALEVEQLAPYVGL 125 Query 173 LSEGSDADGLRALFTTWITAPQPDIDVLVPAVLDGAIQYVS---SGATEFGAEAKTVLEL 229 L+ D DGLRALFTTWIT P P + L+P VLDG ++Y+S + EF EA+T LEL Sbjct 126 LAGQPDPDGLRALFTTWITLPSPALSALLPPVLDGCVRYLSRPDAAEAEFVPEARTALEL 185 Query 230 GERYPGDAGVLAALLLNRISLAPGEAIFLPAGNLHAYVRGFGVEVMANSDNVLRGGLTPK 289 E YPGDAGVLAALLLNRI+L PG+ +FL AGNLHAY+ G VE+MANSDNVLRGGLTPK Sbjct 186 SEGYPGDAGVLAALLLNRITLEPGQGLFLAAGNLHAYLHGTAVEIMANSDNVLRGGLTPK 245 Query 290 HVDVPELLRVLDFAPTPKARLRP-PIRREGLGLVFETPTDEFAATLLVLDGDHLGHEVDA 348 HVDVPELLRVLDF L P P R G + + TP EF T + LD G EV Sbjct 246 HVDVPELLRVLDFDSVDVPLLAPAPTGRPG-EVAYATPAAEFVLTRIDLDASDAGSEVSV 304 Query 349 SSGHDGPQILLCTEGSATVHGKCGSLTLQRGTAAWVAADDGPIRLTA-GQPAKLFRATVG 407 + DGPQILLCT G+A + SL L+RG AAW++A D + + A ++FRA VG Sbjct 305 TIEPDGPQILLCTSGAAKLGCGPHSLVLERGGAAWISASDNEVHIQACADDTQIFRAGVG 364 >gi|258654287|ref|YP_003203443.1| mannose-6-phosphate isomerase, class I [Nakamurella multipartita DSM 44233] gi|258557512|gb|ACV80454.1| mannose-6-phosphate isomerase, class I [Nakamurella multipartita DSM 44233] Length=406 Score = 363 bits (931), Expect = 4e-98, Method: Compositional matrix adjust. Identities = 223/419 (54%), Positives = 263/419 (63%), Gaps = 28/419 (6%) Query 4 LRGALRTYAWGSRTAIAEFTGRPVPAAHPEAELWFGAHPGDP-AWLQTPHGQTS------ 56 +R +R YAWGSRTAIA+ G P PA HP+AELW GAHP DP A L P G Sbjct 1 MRNRIRPYAWGSRTAIADLLGEPSPAPHPQAELWVGAHPADPSALLDGPGGSVDEPGAPT 60 Query 57 --LLEALVADPEGQLGSASRARFGDVLPFLVKVLAADEPLSLQAHPSAEQAVEGYLREER 114 L E + ADP LG RFG LPFL+KVLAA EPLSLQAHPSA QA G+ EE Sbjct 61 RPLTEVIAADPVDTLGRPVHERFGSRLPFLLKVLAAAEPLSLQAHPSAAQAERGFALEEA 120 Query 115 MGIPVSSPVRNYRDTSHKPELLVALQPFEALAGFREAARTTELLRALAVSDLDPFIDLLS 174 GIP++SP RNYRD+ HKPEL+ AL FEAL GFRE +RT LL AL V LD ++ LLS Sbjct 121 AGIPLTSPQRNYRDSWHKPELICALTEFEALCGFREPSRTVHLLAALEVPALDHYLGLLS 180 Query 175 EGSDADGLRALFTTWITAPQPDIDVLVPAVLDGAIQYVSSGATEFGAEAKTVLELGERYP 234 D G RALF++ IT P + L+ VL ++ V A EF E +T L LGERYP Sbjct 181 GQPDEHGTRALFSSIITIPPSTLGPLLSDVLAACVRRVQV-ADEFATEYRTALALGERYP 239 Query 235 GDAGVLAALLLNRISLAPGEAIFLPAGNLHAYVRGFGVEVMANSDNVLRGGLTPKHVDVP 294 GD GVLA+LLLNRI+L PG+A++LP GNLHAY+ G G+EVMANSDNVLRGGLTPKHVDVP Sbjct 240 GDPGVLASLLLNRITLQPGQALYLPGGNLHAYLAGVGIEVMANSDNVLRGGLTPKHVDVP 299 Query 295 ELLRVLDFAPTPKARLRPPIRREGLGL----VFETPTDEFAATLLVLDGDHLGHEVDASS 350 EL++VLDF P PI GL V+ TPT EF L L+ E+ Sbjct 300 ELMKVLDFHPGDV-----PILHGDPGLPGERVYRTPTPEF--RLSRLEPVPGRREIT--- 349 Query 351 GHDGPQILLCTEGSATVHGKCGS-LTLQRGTAAWVAADDGPIRLTAGQPAKLFRATVGL 408 H GPQ+LL EG V + G LT+ RG + W+ A DG + AG A +RAT GL Sbjct 350 -HAGPQVLLVVEGELQVADERGRILTVPRGRSVWIGAHDG-LVWVAGD-AVAYRATDGL 405 >gi|344043751|gb|EGV39439.1| mannose-6-phosphate isomerase [Corynebacterium glutamicum S9114] Length=394 Score = 352 bits (903), Expect = 7e-95, Method: Compositional matrix adjust. Identities = 194/408 (48%), Positives = 258/408 (64%), Gaps = 16/408 (3%) Query 1 VELLRGALRTYAWGSRTAIAEFTGRPVPAAHPEAELWFGAHPGDPAWLQTPHGQTSLLEA 60 +ELL G+LRTY WGSRT IA+ G P++ PEAE+WFGAHPG P+ + G +L E Sbjct 1 MELLEGSLRTYPWGSRTLIADLKGEESPSSRPEAEVWFGAHPGSPSTI----GGNALNEV 56 Query 61 LVADPEGQLGSASRARFGDVLPFLVKVLAADEPLSLQAHPSAEQAVEGYLREERMGIPVS 120 + A+PE LG+ F + LPFL+K+LAA PLSLQAHPS EQA EG+ RE GI ++ Sbjct 57 IAANPEEALGTRVAEAFENELPFLLKILAAGAPLSLQAHPSLEQAREGFARENSAGIDLA 116 Query 121 SPVRNYRDTSHKPELLVALQPFEALAGFREAARTTELLRALAVSDLDPFIDLLSEGSDAD 180 +P RNYRD +HKPEL+VAL F A+AGFR T + ALA LD + +L+ ++ + Sbjct 117 APNRNYRDPNHKPELIVALTEFIAMAGFRPLRNTLTIFDALACEPLDRYRSMLTVDNEEE 176 Query 181 GLRALFTTWITAPQPDIDVLVPAVLDGAIQYV--SSGATEFGAEAKTVLELGERYPGDAG 238 LRALFTTWIT P L+ A++ A Y+ S + ++EL E+YPGD G Sbjct 177 SLRALFTTWITIPIGKRHELIDALISNAHTYLEASDRDEDIAFVLSHIIELNEQYPGDVG 236 Query 239 VLAALLLNRISLAPGEAIFLPAGNLHAYVRGFGVEVMANSDNVLRGGLTPKHVDVPELLR 298 VL ALLLN LAPGEA++L A NLHAY+ G GVE+MANSDNVLRGGLT K+VDVPEL+R Sbjct 237 VLGALLLNFYKLAPGEALYLDAANLHAYISGLGVEIMANSDNVLRGGLTSKYVDVPELVR 296 Query 299 VLDFAPTPKARLRPPIRREGLGLVFETPTDEFAATLLVLDGDHLGHEVDASSGHDGPQIL 358 VLDF AR+ + +G + P +EF + + G +A + HDGP I+ Sbjct 297 VLDFNSLENARVD--VEEDGATTHYPVPINEFQLDRVAVQG-------EAEANHDGPMIV 347 Query 359 LCTEGSATVHGKCGSLTLQRGTAAWVAADDGPIRLTAGQPAKLFRATV 406 LCT G+ ++ +L + G AAWV A+D I + + + A++F A V Sbjct 348 LCTSGTVSLEAGEKTLEIAAGHAAWVPANDPTIAMRS-EDAEVFLARV 394 >gi|145294910|ref|YP_001137731.1| hypothetical protein cgR_0857 [Corynebacterium glutamicum R] gi|140844830|dbj|BAF53829.1| hypothetical protein [Corynebacterium glutamicum R] Length=394 Score = 352 bits (902), Expect = 9e-95, Method: Compositional matrix adjust. Identities = 194/408 (48%), Positives = 258/408 (64%), Gaps = 16/408 (3%) Query 1 VELLRGALRTYAWGSRTAIAEFTGRPVPAAHPEAELWFGAHPGDPAWLQTPHGQTSLLEA 60 +ELL G+LRTY WGSRT IA+ G P++ PEAE+WFGAHPG P+ + G +L E Sbjct 1 MELLEGSLRTYPWGSRTLIADLKGEESPSSRPEAEVWFGAHPGSPSTI----GGNALNEV 56 Query 61 LVADPEGQLGSASRARFGDVLPFLVKVLAADEPLSLQAHPSAEQAVEGYLREERMGIPVS 120 + A+PE LG+ F + LPFL+K+LAA PLSLQAHPS EQA EG+ RE GI ++ Sbjct 57 IAANPEEALGTRVAEAFENELPFLLKILAAGAPLSLQAHPSLEQAREGFARENSAGIDLA 116 Query 121 SPVRNYRDTSHKPELLVALQPFEALAGFREAARTTELLRALAVSDLDPFIDLLSEGSDAD 180 +P RNYRD +HKPEL+VAL F A+AGFR T + ALA LD + +L+ ++ + Sbjct 117 APNRNYRDPNHKPELIVALTDFIAMAGFRPLRNTLTIFDALACEPLDRYRSMLTVDNEEE 176 Query 181 GLRALFTTWITAPQPDIDVLVPAVLDGAIQYV--SSGATEFGAEAKTVLELGERYPGDAG 238 LRALFTTWIT P L+ A++ A Y+ S + ++EL E+YPGD G Sbjct 177 SLRALFTTWITIPIGKRHELIDALISNAHTYLEASDRDEDIAFVLSHIIELNEQYPGDVG 236 Query 239 VLAALLLNRISLAPGEAIFLPAGNLHAYVRGFGVEVMANSDNVLRGGLTPKHVDVPELLR 298 VL ALLLN LAPGEA++L A NLHAY+ G GVE+MANSDNVLRGGLT K+VDVPEL+R Sbjct 237 VLGALLLNFYKLAPGEALYLDAANLHAYISGLGVEIMANSDNVLRGGLTSKYVDVPELVR 296 Query 299 VLDFAPTPKARLRPPIRREGLGLVFETPTDEFAATLLVLDGDHLGHEVDASSGHDGPQIL 358 VLDF AR+ + +G + P +EF + + G +A + HDGP I+ Sbjct 297 VLDFNSLENARVD--VEEDGATTHYPVPINEFQLDRVAVQG-------EAEANHDGPMIV 347 Query 359 LCTEGSATVHGKCGSLTLQRGTAAWVAADDGPIRLTAGQPAKLFRATV 406 LCT G+ ++ +L + G AAWV A+D I + + + A++F A V Sbjct 348 LCTSGTVSLEAGEKTLEVAAGHAAWVPANDPTIAMRS-EDAEVFLARV 394 >gi|19551976|ref|NP_599978.1| phosphomannose isomerase [Corynebacterium glutamicum ATCC 13032] gi|62389637|ref|YP_225039.1| mannose-6-phosphate isomerase [Corynebacterium glutamicum ATCC 13032] gi|21323514|dbj|BAB98141.1| Phosphomannose isomerase [Corynebacterium glutamicum ATCC 13032] gi|41324972|emb|CAF19453.1| MANNOSE-6-PHOSPHATE ISOMERASE [Corynebacterium glutamicum ATCC 13032] Length=394 Score = 351 bits (901), Expect = 1e-94, Method: Compositional matrix adjust. Identities = 194/408 (48%), Positives = 257/408 (63%), Gaps = 16/408 (3%) Query 1 VELLRGALRTYAWGSRTAIAEFTGRPVPAAHPEAELWFGAHPGDPAWLQTPHGQTSLLEA 60 +ELL G+LRTY WGSRT IA+ G P++ PEAE+WFGAHPG P+ + G +L E Sbjct 1 MELLEGSLRTYPWGSRTLIADLKGEESPSSRPEAEVWFGAHPGSPSTI----GGNALNEV 56 Query 61 LVADPEGQLGSASRARFGDVLPFLVKVLAADEPLSLQAHPSAEQAVEGYLREERMGIPVS 120 + A+PE LG+ F + LPFL+K+LAA PLSLQAHPS EQA EG+ RE GI + Sbjct 57 IAANPEEALGTRVAEAFENELPFLLKILAAGAPLSLQAHPSLEQAREGFARENSAGIDLG 116 Query 121 SPVRNYRDTSHKPELLVALQPFEALAGFREAARTTELLRALAVSDLDPFIDLLSEGSDAD 180 +P RNYRD +HKPEL+VAL F A+AGFR T + ALA LD + +L+ ++ + Sbjct 117 APNRNYRDPNHKPELIVALTEFIAMAGFRPLRNTLTIFDALACEPLDRYRSMLTVDNEEE 176 Query 181 GLRALFTTWITAPQPDIDVLVPAVLDGAIQYV--SSGATEFGAEAKTVLELGERYPGDAG 238 LRALFTTWIT P L+ A++ A Y+ S + ++EL E+YPGD G Sbjct 177 SLRALFTTWITIPIGKRHELIDALISNAHTYLEASDRDEDIAFVLSHIIELNEQYPGDVG 236 Query 239 VLAALLLNRISLAPGEAIFLPAGNLHAYVRGFGVEVMANSDNVLRGGLTPKHVDVPELLR 298 VL ALLLN LAPGEA++L A NLHAY+ G GVE+MANSDNVLRGGLT K+VDVPEL+R Sbjct 237 VLGALLLNFYKLAPGEALYLDAANLHAYISGLGVEIMANSDNVLRGGLTSKYVDVPELVR 296 Query 299 VLDFAPTPKARLRPPIRREGLGLVFETPTDEFAATLLVLDGDHLGHEVDASSGHDGPQIL 358 VLDF AR+ + +G + P +EF + + G +A + HDGP I+ Sbjct 297 VLDFNSLENARVD--VEEDGATTHYPVPINEFQLDRVAVQG-------EAEANHDGPMIV 347 Query 359 LCTEGSATVHGKCGSLTLQRGTAAWVAADDGPIRLTAGQPAKLFRATV 406 LCT G+ ++ +L + G AAWV A+D I + + + A++F A V Sbjct 348 LCTSGTVSLEAGEKTLEVAAGHAAWVPANDPTIAMRS-EDAEVFLARV 394 >gi|306835483|ref|ZP_07468500.1| mannose-6-phosphate isomerase [Corynebacterium accolens ATCC 49726] gi|304568649|gb|EFM44197.1| mannose-6-phosphate isomerase [Corynebacterium accolens ATCC 49726] Length=417 Score = 350 bits (897), Expect = 3e-94, Method: Compositional matrix adjust. Identities = 204/427 (48%), Positives = 262/427 (62%), Gaps = 31/427 (7%) Query 1 VELLRGALRTYAWGSRTAIAEFTGRPVPAAHPEAELWFGAHPGDPAWLQTPHGQTSLLEA 60 ++LL GA R Y+WGSRT I E G A P AELWFGAHPGDP+ T GQ L E Sbjct 1 MQLLEGATRNYSWGSRTLIPELRGEEA-AEKPVAELWFGAHPGDPS---TVDGQL-LNEV 55 Query 61 LVADPEGQLGSASRARFGDVLPFLVKVLAADEPLSLQAHPSAEQAVEGYLREERMGIPVS 120 + ADPEGQLG+ +G+ LPFL+K+LAA++PLSLQAHPS EQA EG+ RE GI + Sbjct 56 IAADPEGQLGARVYKEYGENLPFLLKILAAEDPLSLQAHPSKEQAEEGFARENEAGIALQ 115 Query 121 SPVRNYRDTSHKPELLVALQPFEALAGFREAARTTELLRALAVSDLDPFIDLL----SEG 176 + RNY+D +HKPEL+VAL F A+AGFR A+T EL AL +L+ ++ +L E Sbjct 116 AANRNYKDDNHKPELIVALSDFYAMAGFRPLAQTRELFAALQCPELERYLAMLDDDPEES 175 Query 177 SDADGLRALFTTWITAPQPDIDVLVPAVLDGAIQYVSSGATEFGAEA-KTVLELGERYPG 235 S++ LR LFTTWIT P L+ A++ + +++ T++ A TV++L +RYPG Sbjct 176 SESANLRVLFTTWITIPSAKRKELIKAIVAAGERLITADPTDWKARVMATVVDLNDRYPG 235 Query 236 DAGVLAALLLNRISLAPGEAIFLPAGNLHAYVRGFGVEVMANSDNVLRGGLTPKHVDVPE 295 D GVL ALLLN I LAPGEA++L AG LHAYV G GVE+MANSDNVLRGGLTPK VDVPE Sbjct 236 DIGVLGALLLNHIELAPGEAVYLDAGQLHAYVSGLGVEIMANSDNVLRGGLTPKFVDVPE 295 Query 296 LLRVLDFAPTPKARLRPPIRRE------GLGLVFETPTDEFAATLLVLDGDHLGHEVDAS 349 L++VL +A + R++ ++ + P DEF +LD LG + Sbjct 296 LVKVLTYAAATEPRVQQKDKQHQDNVHGAAAWSYPVPIDEF-----LLDRAELGPDSSVD 350 Query 350 SGHDGPQILLCTEGSATVHGKCG-SLTLQRGTAAWVAADDGPIRLTA---------GQPA 399 +DGP I LCT GS + G L L G AAW+ A DG + A G A Sbjct 351 LDYDGPTIALCTGGSLNLRNAAGEELILSPGQAAWLPASDGMVTAQAHAVEKENPEGSTA 410 Query 400 KLFRATV 406 +LF A V Sbjct 411 QLFVARV 417 >gi|227502884|ref|ZP_03932933.1| possible mannose-6-phosphate isomerase [Corynebacterium accolens ATCC 49725] gi|227076614|gb|EEI14577.1| possible mannose-6-phosphate isomerase [Corynebacterium accolens ATCC 49725] Length=417 Score = 347 bits (890), Expect = 2e-93, Method: Compositional matrix adjust. Identities = 203/427 (48%), Positives = 261/427 (62%), Gaps = 31/427 (7%) Query 1 VELLRGALRTYAWGSRTAIAEFTGRPVPAAHPEAELWFGAHPGDPAWLQTPHGQTSLLEA 60 ++LL GA R Y+WGSRT I E G A P AELWFGAHPGDP+ T GQ L E Sbjct 1 MQLLEGATRNYSWGSRTLIPELRGEEA-AEKPVAELWFGAHPGDPS---TVDGQL-LNEV 55 Query 61 LVADPEGQLGSASRARFGDVLPFLVKVLAADEPLSLQAHPSAEQAVEGYLREERMGIPVS 120 + ADPEGQLG+ +G+ LPFL+K+LAA++PLSLQAHPS EQA EG+ RE GI + Sbjct 56 IAADPEGQLGARVYKEYGENLPFLLKILAAEDPLSLQAHPSKEQAEEGFARENEAGIALQ 115 Query 121 SPVRNYRDTSHKPELLVALQPFEALAGFREAARTTELLRALAVSDLDPFIDLL----SEG 176 + RNY+D +HKPEL+VAL F A+AGFR A+T EL AL +L+ ++ +L +E Sbjct 116 AANRNYKDDNHKPELIVALSDFYAMAGFRPLAQTRELFAALECPELERYLAMLDDDPAES 175 Query 177 SDADGLRALFTTWITAPQPDIDVLVPAVLDGAIQYVSSGATEFGAEAK-TVLELGERYPG 235 S++ LR LFTTWIT P L+ A++ + ++ ++ A TV++L +RYPG Sbjct 176 SESANLRVLFTTWITIPSAKRKELIKAIVAAGERLIAVDPKDWKARVMATVVDLNDRYPG 235 Query 236 DAGVLAALLLNRISLAPGEAIFLPAGNLHAYVRGFGVEVMANSDNVLRGGLTPKHVDVPE 295 D GVL ALLLN I LAPGEA++L AG LHAYV G GVE+MANSDNVLRGGLTPK VDVPE Sbjct 236 DIGVLGALLLNHIELAPGEAVYLDAGQLHAYVSGLGVEIMANSDNVLRGGLTPKFVDVPE 295 Query 296 LLRVLDFAPTPKARLRPPIRRE------GLGLVFETPTDEFAATLLVLDGDHLGHEVDAS 349 L++VL +A + R++ ++ + P DEF +LD LG + Sbjct 296 LVKVLTYAAATEPRVQQKDKQHQDNVHGAAAWSYPVPIDEF-----LLDRAELGPDSSVD 350 Query 350 SGHDGPQILLCTEGSATVHGKCG-SLTLQRGTAAWVAADDGPIRLTA---------GQPA 399 +DGP I LCT GS + G L L G AAW+ A DG + A G A Sbjct 351 LDYDGPTIALCTGGSLNLRNAAGEELILSPGQAAWLPASDGMVTAQAHAVEKENPEGSTA 410 Query 400 KLFRATV 406 +LF A V Sbjct 411 QLFVARV 417 >gi|300857929|ref|YP_003782912.1| mannose-6-phosphate isomerase [Corynebacterium pseudotuberculosis FRC41] gi|300685383|gb|ADK28305.1| mannose-6-phosphate isomerase [Corynebacterium pseudotuberculosis FRC41] gi|302205658|gb|ADL10000.1| Mannose-6-phosphate isomerase manA [Corynebacterium pseudotuberculosis C231] gi|302330209|gb|ADL20403.1| Mannose-6-phosphate isomerase manA [Corynebacterium pseudotuberculosis 1002] gi|308275893|gb|ADO25792.1| Phosphomannose isomerase [Corynebacterium pseudotuberculosis I19] gi|341824323|gb|AEK91844.1| Mannose-6-phosphate isomerase manA [Corynebacterium pseudotuberculosis PAT10] Length=385 Score = 345 bits (886), Expect = 7e-93, Method: Compositional matrix adjust. Identities = 200/408 (50%), Positives = 253/408 (63%), Gaps = 25/408 (6%) Query 1 VELLRGALRTYAWGSRTAIAEFTGRPVPAAHPEAELWFGAHPGDPAWLQTPHGQTSLLEA 60 ++LL + + YAWGSRT I G P AELW+GAHPG P+ + G SL E Sbjct 1 MQLLSPSAQAYAWGSRTLIQNLRGEE-QGTSPIAELWYGAHPGGPSKI----GDESLAEH 55 Query 61 LVADPEGQLGSASRARFGDVLPFLVKVLAADEPLSLQAHPSAEQAVEGYLREERMGIPVS 120 + A PE QLG + FG+ LPFL+K+LAAD+PLSLQAHPS EQA EG+ R+ GI + Sbjct 56 IAAAPEQQLGHRVHSEFGERLPFLLKILAADQPLSLQAHPSLEQAQEGFARDNEQGIQLG 115 Query 121 SPVRNYRDTSHKPELLVALQPFEALAGFREAARTTELLRALAVSDLDPFIDLLSEG--SD 178 + RNY+D +HKPELL+AL F A+AGFR A+T E+LR L +L+ +I ++ + + Sbjct 116 AHNRNYKDDNHKPELLIALTEFHAMAGFRPLAKTLEMLRFLDCEELERYIAMVVDNPLKE 175 Query 179 ADGLRALFTTWITAPQPDIDVLVPAVLDGAIQYVSSGATEFGAEAKTVLELGERYPGDAG 238 +D LRALFTTWIT P + L+ AV+ A + S A K ++ L E+YPGD G Sbjct 176 SDSLRALFTTWITIPTANRRDLIVAVVSSAKEKAESAPEWMSAALKNIVLLNEQYPGDVG 235 Query 239 VLAALLLNRISLAPGEAIFLPAGNLHAYVRGFGVEVMANSDNVLRGGLTPKHVDVPELLR 298 VL A+LLN + L PGEAI+L AGNLHAYVRG GVE+MANSDNVLRGGLT KHVDVPEL+R Sbjct 236 VLGAILLNYVVLQPGEAIYLDAGNLHAYVRGLGVEIMANSDNVLRGGLTSKHVDVPELVR 295 Query 299 VLDFAPTPKARLRPPIRREGLGLVFETPTDEFAATLLVLDGDHLGHEVDASSGHDGPQIL 358 VL F A L PI G V+ P +EFA + LD + HDGP IL Sbjct 296 VLKF-----ASLENPIVEAESG-VYPVPINEFAIKRIDLD------KTAEKIAHDGPAIL 343 Query 359 LCTEGSATVHGKCGSLTLQRGTAAWVAADDGPIRLTAGQPAKLFRATV 406 LCT G+ V G +TL A W++A D + GQ +LF ATV Sbjct 344 LCTAGTVEV----GGVTLNPTQALWLSAADAEVE-ARGQ-GQLFVATV 385 >gi|25027320|ref|NP_737374.1| putative mannose-6-phosphate isomerase [Corynebacterium efficiens YS-314] gi|259506542|ref|ZP_05749444.1| mannose-6-phosphate isomerase [Corynebacterium efficiens YS-314] gi|23492601|dbj|BAC17574.1| putative mannose-6-phosphate isomerase [Corynebacterium efficiens YS-314] gi|259165962|gb|EEW50516.1| mannose-6-phosphate isomerase [Corynebacterium efficiens YS-314] Length=396 Score = 344 bits (883), Expect = 1e-92, Method: Compositional matrix adjust. Identities = 198/410 (49%), Positives = 249/410 (61%), Gaps = 18/410 (4%) Query 1 VELLRGALRTYAWGSRTAIAEFTGRPVPAAHPEAELWFGAHPGDPAWLQTPHGQTSLLEA 60 +ELL G LR Y WGSRT I E G P+ PEAE+WFGAHPG P+ + T+L + Sbjct 1 MELLEGTLRAYPWGSRTLIPEMRGEEAPSGRPEAEVWFGAHPGAPSTING----TALNQL 56 Query 61 LVADPEGQLGSASRARFGDVLPFLVKVLAADEPLSLQAHPSAEQAVEGYLREERMGIPVS 120 + DP G LG F LPFL+K+LAA PLSLQAHPS EQA EG+ RE GI + Sbjct 57 IADDPVGMLGERVAREFDGQLPFLLKILAAGAPLSLQAHPSLEQAREGFQRENEAGIEFT 116 Query 121 SPVRNYRDTSHKPELLVALQPFEALAGFREAARTTELLRALAVSDLDPFIDLLSEGSDAD 180 +P RNYRD +HKPEL+VAL F A+AGFR ART E+ A+ +LD + +++ ++ + Sbjct 117 APNRNYRDANHKPELIVALSDFIAMAGFRPLARTLEIFDAIECHELDHYRSMIAVDAEEE 176 Query 181 GLRALFTTWITAPQPDIDVLVPAVLDGAIQYVSSGATEFGAEAKT-VLELGERYPGDAGV 239 LRALFTTWIT P L+ A++ A +Y+ G E+ + ++EL +RYPGD GV Sbjct 177 SLRALFTTWITIPVTKRHELINAIIASAHRYLEQGGQEWIRFVLSHIVELHDRYPGDVGV 236 Query 240 LAALLLNRISLAPGEAIFLPAGNLHAYVRGFGVEVMANSDNVLRGGLTPKHVDVPELLRV 299 L ALLLN L PGE I+L AGNLHAY+ G GVE+MANSDNVLRGGLT K+VDVPEL+RV Sbjct 237 LGALLLNFYQLKPGEGIYLDAGNLHAYIYGLGVEIMANSDNVLRGGLTSKYVDVPELVRV 296 Query 300 LDFAPTPKARLRPPIRREGLGLVFETPTDEFAATLLVLDGDHLGHEVDASSGHDGPQILL 359 LDF A + EG + P EF + L G H + HDGP I+L Sbjct 297 LDFKSLGNAVV--DCVSEGNIHRYPVPVSEFTLDRVRLTGSH-------DAVHDGPMIIL 347 Query 360 CTE---GSATVHGKCGSLTLQRGTAAWVAADDGPIRLTAGQPAKLFRATV 406 CTE G + + L G A WV A DG I +TA A++F ATV Sbjct 348 CTESAGGPVLLEHGGQRIELTAGYAVWVPASDGLIGMTA-DDAEVFIATV 396 >gi|296118800|ref|ZP_06837376.1| mannose-6-phosphate isomerase, class I [Corynebacterium ammoniagenes DSM 20306] gi|295968289|gb|EFG81538.1| mannose-6-phosphate isomerase, class I [Corynebacterium ammoniagenes DSM 20306] Length=406 Score = 342 bits (878), Expect = 5e-92, Method: Compositional matrix adjust. Identities = 193/416 (47%), Positives = 259/416 (63%), Gaps = 20/416 (4%) Query 1 VELLRGALRTYAWGSRTAIAEFTGRPVPAAHPEAELWFGAHPGDPAWLQTPHGQTSLLEA 60 ++LL A RTY+WGS+T I G+ + +P AELW+GAHPG PA ++ L Sbjct 1 MQLLNSATRTYSWGSKTLIPHLQGKAA-SNYPIAELWYGAHPGGPATVE----DEPLNAI 55 Query 61 LVADPEGQLGSASRARFGDVLPFLVKVLAADEPLSLQAHPSAEQAVEGYLREERMGIPVS 120 + ADP+ LG A F + LPFL+K+L+ADEPLSLQAHPS EQA++G+ RE G+ + Sbjct 56 IAADPQAALGENVAAEFDNKLPFLLKILSADEPLSLQAHPSKEQALQGFARENSQGVAMD 115 Query 121 SPVRNYRDTSHKPELLVALQPFEALAGFREAARTTELLRALAVSDLDPFIDL------LS 174 +P R+Y+D +HKPEL+VAL F A+AGFR T EL AL +L+ + + L+ Sbjct 116 APQRSYKDDNHKPELIVALTDFYAMAGFRPLVHTRELFDALDCEELNRYAHMHIADGRLT 175 Query 175 EGSDADGLRALFTTWITAPQPDIDVLVPAVLDGAIQYVSSGATEFGAE--AKTVLELGER 232 + ++D LRALFTTWIT P L+ A+++ + Q + + ++ +T+++L E Sbjct 176 QDEESDSLRALFTTWITIPATTRRELIAALMECSKQLLETLHSDSWMRPVLETLIDLDEL 235 Query 233 YPGDAGVLAALLLNRISLAPGEAIFLPAGNLHAYVRGFGVEVMANSDNVLRGGLTPKHVD 292 YPGD GVL ALLLN + L+PGEAI+L AG LHAYVRG GVE+MANSDNVLRGGLTPKHVD Sbjct 236 YPGDVGVLGALLLNHVQLSPGEAIYLDAGQLHAYVRGLGVEIMANSDNVLRGGLTPKHVD 295 Query 293 VPELLRVLDFAPTPKARLRP-PIRREGLGLVFETPTDEFAATLLVLDGDHLGHEVDASSG 351 VPEL++VL F R+ + + + P +E+A T L G EV S Sbjct 296 VPELVKVLSFNTIADPRVEQISLSDSAQVMNYPVPVNEYALTRCDLKA---GQEVTTES- 351 Query 352 HDGPQILLCTEGSATVHGKCGS-LTLQRGTAAWVAADDGPIRLTAGQPAKLFRATV 406 DGP I+LCTEGS + + G+ L L AAWV ADDG I L+ A+ F A V Sbjct 352 -DGPAIILCTEGSLQLTAQDGTCLELSPSDAAWVPADDGDITLSTKDKAQAFIARV 406 Lambda K H 0.318 0.137 0.408 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 813232817712 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40