BLASTP 2.2.25+
Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
15,229,318 sequences; 5,219,829,388 total letters
Query= Rv3271c
Length=222
Score E
Sequences producing significant alignments: (Bits) Value
gi|15610407|ref|NP_217788.1| integral membrane protein [Mycobact... 427 4e-118
gi|298526747|ref|ZP_07014156.1| conserved hypothetical protein [... 426 8e-118
gi|308232402|ref|ZP_07415937.2| conserved membrane protein [Myco... 392 2e-107
gi|240172496|ref|ZP_04751155.1| putative integral membrane prote... 317 1e-84
gi|296168933|ref|ZP_06850602.1| integral membrane protein [Mycob... 303 1e-80
gi|118618087|ref|YP_906419.1| hypothetical protein MUL_2617 [Myc... 301 4e-80
gi|183981292|ref|YP_001849583.1| hypothetical protein MMAR_1270 ... 301 5e-80
gi|296165746|ref|ZP_06848261.1| integral membrane protein [Mycob... 290 1e-76
gi|254821356|ref|ZP_05226357.1| putative integral membrane prote... 288 3e-76
gi|342861475|ref|ZP_08718122.1| putative integral membrane prote... 278 5e-73
gi|333991662|ref|YP_004524276.1| hypothetical protein JDM601_302... 240 1e-61
gi|296164269|ref|ZP_06846857.1| integral membrane protein [Mycob... 237 1e-60
gi|296170503|ref|ZP_06852090.1| integral membrane protein [Mycob... 235 3e-60
gi|120404603|ref|YP_954432.1| putative integral membrane protein... 214 8e-54
gi|337766727|emb|CCB75438.1| putative conserved integral membran... 181 8e-44
gi|271968870|ref|YP_003343066.1| integral membrane protein [Stre... 177 8e-43
gi|256825296|ref|YP_003149256.1| Co/Zn/Cd cation transporter [Ky... 125 4e-27
gi|157283867|ref|YP_001468135.1| cation efflux protein [Kineococ... 122 4e-26
gi|311743732|ref|ZP_07717538.1| cation efflux protein [Aeromicro... 122 5e-26
gi|284028079|ref|YP_003378010.1| hypothetical protein Kfla_0082 ... 118 6e-25
gi|84495274|ref|ZP_00994393.1| putative integral membrane protei... 117 2e-24
gi|311744618|ref|ZP_07718417.1| integral membrane protein [Aerom... 115 6e-24
gi|118473825|ref|YP_889838.1| integral membrane protein [Mycobac... 114 1e-23
gi|182437562|ref|YP_001825281.1| putative integral membrane prot... 108 4e-22
gi|169629689|ref|YP_001703338.1| integral membrane protein [Myco... 108 4e-22
gi|296268434|ref|YP_003651066.1| cation efflux protein [Thermobi... 108 5e-22
gi|226309136|ref|YP_002769096.1| hypothetical protein RER_56490 ... 106 2e-21
gi|116662405|ref|YP_829458.1| cation efflux protein [Arthrobacte... 106 2e-21
gi|317125775|ref|YP_004099887.1| cation efflux protein [Intraspo... 106 3e-21
gi|119960546|ref|YP_947144.1| cation efflux family protein [Arth... 105 7e-21
gi|111021225|ref|YP_704197.1| hypothetical protein RHA1_ro04248 ... 104 1e-20
gi|291299242|ref|YP_003510520.1| cation efflux protein [Stackebr... 103 2e-20
gi|328883501|emb|CCA56740.1| probable integral membrane protein ... 103 2e-20
gi|331694410|ref|YP_004330649.1| cation efflux protein [Pseudono... 102 3e-20
gi|336179230|ref|YP_004584605.1| cation efflux protein [Frankia ... 102 4e-20
gi|145224482|ref|YP_001135160.1| Co/Zn/Cd cation transporters-li... 102 5e-20
gi|120404892|ref|YP_954721.1| cation efflux protein [Mycobacteri... 101 8e-20
gi|126436473|ref|YP_001072164.1| hypothetical protein Mjls_3897 ... 100 2e-19
gi|86741408|ref|YP_481808.1| putative integral membrane protein ... 99.4 3e-19
gi|254411318|ref|ZP_05025095.1| cation efflux family protein [Mi... 99.4 4e-19
gi|327309763|ref|YP_004336661.1| cation efflux protein [Pseudono... 98.2 7e-19
gi|148272396|ref|YP_001221957.1| CDF family cation efflux protei... 98.2 8e-19
gi|238059826|ref|ZP_04604535.1| Co:Zn:Cd cation transporter [Mic... 97.1 2e-18
gi|220914056|ref|YP_002489365.1| cation efflux protein [Arthroba... 96.7 2e-18
gi|183982149|ref|YP_001850440.1| metal transport protein [Mycoba... 95.5 5e-18
gi|170782241|ref|YP_001710574.1| putative integral membrane prot... 95.1 7e-18
gi|271966330|ref|YP_003340526.1| Co/Zn/Cd cation transporter-lik... 95.1 7e-18
gi|291302839|ref|YP_003514117.1| cation efflux protein [Stackebr... 94.7 8e-18
gi|284993397|ref|YP_003411952.1| cation efflux protein [Geoderma... 94.7 8e-18
gi|84496059|ref|ZP_00994913.1| putative integral membrane protei... 94.7 9e-18
>gi|15610407|ref|NP_217788.1| integral membrane protein [Mycobacterium tuberculosis H37Rv]
gi|15842861|ref|NP_337898.1| hypothetical protein MT3371 [Mycobacterium tuberculosis CDC1551]
gi|31794451|ref|NP_856944.1| integral membrane protein [Mycobacterium bovis AF2122/97]
62 more sequence titles
Length=222
Score = 427 bits (1099), Expect = 4e-118, Method: Compositional matrix adjust.
Identities = 222/222 (100%), Positives = 222/222 (100%), Gaps = 0/222 (0%)
Query 1 METTTEHRDESTLDSPVSVAREAEWQRNVRWARWLAWVSLAVLLTEGAVGLWQGIAVGSV 60
METTTEHRDESTLDSPVSVAREAEWQRNVRWARWLAWVSLAVLLTEGAVGLWQGIAVGSV
Sbjct 1 METTTEHRDESTLDSPVSVAREAEWQRNVRWARWLAWVSLAVLLTEGAVGLWQGIAVGSV 60
Query 61 ALTGWALGGGSEGLASAMVLWRFTGDRTWSATAEHRAQRGVAVSFWLTAPYLVAESIRHL 120
ALTGWALGGGSEGLASAMVLWRFTGDRTWSATAEHRAQRGVAVSFWLTAPYLVAESIRHL
Sbjct 61 ALTGWALGGGSEGLASAMVLWRFTGDRTWSATAEHRAQRGVAVSFWLTAPYLVAESIRHL 120
Query 121 AGEHRAETSVIGIGLTAIALLLMPVLGWANHRVGERLGSGATAGEGTQNYLCAAQAAAVL 180
AGEHRAETSVIGIGLTAIALLLMPVLGWANHRVGERLGSGATAGEGTQNYLCAAQAAAVL
Sbjct 121 AGEHRAETSVIGIGLTAIALLLMPVLGWANHRVGERLGSGATAGEGTQNYLCAAQAAAVL 180
Query 181 LGLAITAVWSNGWWIDPAIGLAIAGIAVWQGIRTWRGHGCGC 222
LGLAITAVWSNGWWIDPAIGLAIAGIAVWQGIRTWRGHGCGC
Sbjct 181 LGLAITAVWSNGWWIDPAIGLAIAGIAVWQGIRTWRGHGCGC 222
>gi|298526747|ref|ZP_07014156.1| conserved hypothetical protein [Mycobacterium tuberculosis 94_M4241A]
gi|298496541|gb|EFI31835.1| conserved hypothetical protein [Mycobacterium tuberculosis 94_M4241A]
Length=222
Score = 426 bits (1096), Expect = 8e-118, Method: Compositional matrix adjust.
Identities = 221/222 (99%), Positives = 221/222 (99%), Gaps = 0/222 (0%)
Query 1 METTTEHRDESTLDSPVSVAREAEWQRNVRWARWLAWVSLAVLLTEGAVGLWQGIAVGSV 60
METTTEHRDESTLDSPVSVAREAEWQRNVRWARWLAWVSLAVLLTEGAVGLWQGIAVGSV
Sbjct 1 METTTEHRDESTLDSPVSVAREAEWQRNVRWARWLAWVSLAVLLTEGAVGLWQGIAVGSV 60
Query 61 ALTGWALGGGSEGLASAMVLWRFTGDRTWSATAEHRAQRGVAVSFWLTAPYLVAESIRHL 120
ALTGWALGGGSEGLASAMVLWRFTGDRTWSATAEHRAQRGVAVSFWLTAPYLVAESIRHL
Sbjct 61 ALTGWALGGGSEGLASAMVLWRFTGDRTWSATAEHRAQRGVAVSFWLTAPYLVAESIRHL 120
Query 121 AGEHRAETSVIGIGLTAIALLLMPVLGWANHRVGERLGSGATAGEGTQNYLCAAQAAAVL 180
AGEHRAETSVIGIGLTAIALLLMPVLGW NHRVGERLGSGATAGEGTQNYLCAAQAAAVL
Sbjct 121 AGEHRAETSVIGIGLTAIALLLMPVLGWVNHRVGERLGSGATAGEGTQNYLCAAQAAAVL 180
Query 181 LGLAITAVWSNGWWIDPAIGLAIAGIAVWQGIRTWRGHGCGC 222
LGLAITAVWSNGWWIDPAIGLAIAGIAVWQGIRTWRGHGCGC
Sbjct 181 LGLAITAVWSNGWWIDPAIGLAIAGIAVWQGIRTWRGHGCGC 222
>gi|308232402|ref|ZP_07415937.2| conserved membrane protein [Mycobacterium tuberculosis SUMu001]
gi|308370211|ref|ZP_07420659.2| conserved membrane protein [Mycobacterium tuberculosis SUMu002]
gi|308373691|ref|ZP_07433335.2| conserved membrane protein [Mycobacterium tuberculosis SUMu005]
13 more sequence titles
Length=206
Score = 392 bits (1006), Expect = 2e-107, Method: Compositional matrix adjust.
Identities = 205/206 (99%), Positives = 206/206 (100%), Gaps = 0/206 (0%)
Query 17 VSVAREAEWQRNVRWARWLAWVSLAVLLTEGAVGLWQGIAVGSVALTGWALGGGSEGLAS 76
+SVAREAEWQRNVRWARWLAWVSLAVLLTEGAVGLWQGIAVGSVALTGWALGGGSEGLAS
Sbjct 1 MSVAREAEWQRNVRWARWLAWVSLAVLLTEGAVGLWQGIAVGSVALTGWALGGGSEGLAS 60
Query 77 AMVLWRFTGDRTWSATAEHRAQRGVAVSFWLTAPYLVAESIRHLAGEHRAETSVIGIGLT 136
AMVLWRFTGDRTWSATAEHRAQRGVAVSFWLTAPYLVAESIRHLAGEHRAETSVIGIGLT
Sbjct 61 AMVLWRFTGDRTWSATAEHRAQRGVAVSFWLTAPYLVAESIRHLAGEHRAETSVIGIGLT 120
Query 137 AIALLLMPVLGWANHRVGERLGSGATAGEGTQNYLCAAQAAAVLLGLAITAVWSNGWWID 196
AIALLLMPVLGWANHRVGERLGSGATAGEGTQNYLCAAQAAAVLLGLAITAVWSNGWWID
Sbjct 121 AIALLLMPVLGWANHRVGERLGSGATAGEGTQNYLCAAQAAAVLLGLAITAVWSNGWWID 180
Query 197 PAIGLAIAGIAVWQGIRTWRGHGCGC 222
PAIGLAIAGIAVWQGIRTWRGHGCGC
Sbjct 181 PAIGLAIAGIAVWQGIRTWRGHGCGC 206
>gi|240172496|ref|ZP_04751155.1| putative integral membrane protein [Mycobacterium kansasii ATCC
12478]
Length=224
Score = 317 bits (811), Expect = 1e-84, Method: Compositional matrix adjust.
Identities = 164/220 (75%), Positives = 185/220 (85%), Gaps = 1/220 (0%)
Query 3 TTTEHRDESTLDSPVSVAREAEWQRNVRWARWLAWVSLAVLLTEGAVGLWQGIAVGSVAL 62
+ T+H T +PV V R++EWQ N WAR LAWVSLAVLL EG +GLWQG+AV SVAL
Sbjct 6 SQTDHCHGVTPATPV-VERDSEWQHNALWARRLAWVSLAVLLIEGGIGLWQGLAVRSVAL 64
Query 63 TGWALGGGSEGLASAMVLWRFTGDRTWSATAEHRAQRGVAVSFWLTAPYLVAESIRHLAG 122
TGWAL GGSEGLASAMVLWRFTG+RT S TAE RAQRGVAVSFWLTAPY+ AES+ HLAG
Sbjct 65 TGWALAGGSEGLASAMVLWRFTGNRTLSQTAERRAQRGVAVSFWLTAPYIAAESLHHLAG 124
Query 123 EHRAETSVIGIGLTAIALLLMPVLGWANHRVGERLGSGATAGEGTQNYLCAAQAAAVLLG 182
AETSV+GI LTAIAL+LMP+LG ANH++G RL SGAT GEGTQNYLCAAQAA VLLG
Sbjct 125 RQHAETSVLGIALTAIALVLMPILGRANHKLGARLKSGATEGEGTQNYLCAAQAAGVLLG 184
Query 183 LAITAVWSNGWWIDPAIGLAIAGIAVWQGIRTWRGHGCGC 222
LAITA WS GWW+DP IGLAI+G+AVWQG+R+W+GH CGC
Sbjct 185 LAITAGWSGGWWVDPVIGLAISGVAVWQGVRSWQGHDCGC 224
>gi|296168933|ref|ZP_06850602.1| integral membrane protein [Mycobacterium parascrofulaceum ATCC
BAA-614]
gi|295896402|gb|EFG76055.1| integral membrane protein [Mycobacterium parascrofulaceum ATCC
BAA-614]
Length=222
Score = 303 bits (775), Expect = 1e-80, Method: Compositional matrix adjust.
Identities = 154/207 (75%), Positives = 174/207 (85%), Gaps = 0/207 (0%)
Query 14 DSPVSVAREAEWQRNVRWARWLAWVSLAVLLTEGAVGLWQGIAVGSVALTGWALGGGSEG 73
+ V+ R A W+R+ WAR LAW+SLA LL EGA+GLWQG+AVGSVALTGWALGGGSE
Sbjct 15 ECAVAATRGAGWRRDAGWARRLAWISLAALLVEGAIGLWQGLAVGSVALTGWALGGGSEA 74
Query 74 LASAMVLWRFTGDRTWSATAEHRAQRGVAVSFWLTAPYLVAESIRHLAGEHRAETSVIGI 133
LASAMVLWRFTGDRT S TAE RAQRGVAVSFWLTAPY+ A+S+ HLA RA+TSV+GI
Sbjct 75 LASAMVLWRFTGDRTLSPTAERRAQRGVAVSFWLTAPYIAADSVAHLADGRRADTSVVGI 134
Query 134 GLTAIALLLMPVLGWANHRVGERLGSGATAGEGTQNYLCAAQAAAVLLGLAITAVWSNGW 193
LTA+AL+LMP+LGWANHRVG RLGS AT GEGTQNYLCA QAA VL GL +TAVW++GW
Sbjct 135 ALTALALMLMPILGWANHRVGARLGSAATEGEGTQNYLCAVQAAGVLAGLGVTAVWADGW 194
Query 194 WIDPAIGLAIAGIAVWQGIRTWRGHGC 220
W DPAIGLA+A IA WQG+R WRGH C
Sbjct 195 WFDPAIGLAVAVIAAWQGVRAWRGHDC 221
>gi|118618087|ref|YP_906419.1| hypothetical protein MUL_2617 [Mycobacterium ulcerans Agy99]
gi|118570197|gb|ABL04948.1| conserved hypothetical membrane protein [Mycobacterium ulcerans
Agy99]
Length=233
Score = 301 bits (772), Expect = 4e-80, Method: Compositional matrix adjust.
Identities = 157/214 (74%), Positives = 174/214 (82%), Gaps = 0/214 (0%)
Query 9 DESTLDSPVSVAREAEWQRNVRWARWLAWVSLAVLLTEGAVGLWQGIAVGSVALTGWALG 68
D ST + + +A WQ+ VRWAR LAW+SLAVL+TEGAVG+W+G+AVGSVALTGWALG
Sbjct 20 DVSTTAAHTGHSGDAAWQQGVRWARRLAWISLAVLVTEGAVGVWEGVAVGSVALTGWALG 79
Query 69 GGSEGLASAMVLWRFTGDRTWSATAEHRAQRGVAVSFWLTAPYLVAESIRHLAGEHRAET 128
G SEGLASAMVLWRFTG RT S TAE RAQRGVAVSFWL AP + AESIRHL +H T
Sbjct 80 GASEGLASAMVLWRFTGSRTLSETAERRAQRGVAVSFWLVAPLVAAESIRHLTDKHEVGT 139
Query 129 SVIGIGLTAIALLLMPVLGWANHRVGERLGSGATAGEGTQNYLCAAQAAAVLLGLAITAV 188
SVIGIGLTA AL++MP+LG ANH++G L SGAT GEGTQNYLCA QAA VLLGLAITA
Sbjct 140 SVIGIGLTAFALVVMPILGRANHKLGVLLQSGATEGEGTQNYLCAGQAAGVLLGLAITAA 199
Query 189 WSNGWWIDPAIGLAIAGIAVWQGIRTWRGHGCGC 222
W GWWIDP IGL IAGIAVWQG+R WRG CGC
Sbjct 200 WPGGWWIDPGIGLVIAGIAVWQGVRAWRGQDCGC 233
>gi|183981292|ref|YP_001849583.1| hypothetical protein MMAR_1270 [Mycobacterium marinum M]
gi|183174618|gb|ACC39728.1| conserved hypothetical membrane protein [Mycobacterium marinum
M]
Length=239
Score = 301 bits (770), Expect = 5e-80, Method: Compositional matrix adjust.
Identities = 157/214 (74%), Positives = 174/214 (82%), Gaps = 0/214 (0%)
Query 9 DESTLDSPVSVAREAEWQRNVRWARWLAWVSLAVLLTEGAVGLWQGIAVGSVALTGWALG 68
D ST + + +A WQ+ VRWAR LAW+SLAVL+TEGAVG+W+G+AVGSVALTGWALG
Sbjct 26 DVSTAPAHTGHSGDAAWQQGVRWARRLAWISLAVLVTEGAVGVWEGVAVGSVALTGWALG 85
Query 69 GGSEGLASAMVLWRFTGDRTWSATAEHRAQRGVAVSFWLTAPYLVAESIRHLAGEHRAET 128
G SEGLASAMVLWRFTG RT S TAE RAQRGVAVSFWL AP + AESIRHL +H T
Sbjct 86 GASEGLASAMVLWRFTGSRTLSETAERRAQRGVAVSFWLVAPLVAAESIRHLTDKHEVGT 145
Query 129 SVIGIGLTAIALLLMPVLGWANHRVGERLGSGATAGEGTQNYLCAAQAAAVLLGLAITAV 188
SVIGIGLTA AL++MP+LG ANH++G L SGAT GEGTQNYLCA QAA VLLGLAITA
Sbjct 146 SVIGIGLTAFALVVMPILGRANHKLGVLLQSGATEGEGTQNYLCAGQAAGVLLGLAITAA 205
Query 189 WSNGWWIDPAIGLAIAGIAVWQGIRTWRGHGCGC 222
W GWWIDP IGL IAGIAVWQG+R WRG CGC
Sbjct 206 WPGGWWIDPGIGLVIAGIAVWQGVRAWRGQDCGC 239
>gi|296165746|ref|ZP_06848261.1| integral membrane protein [Mycobacterium parascrofulaceum ATCC
BAA-614]
gi|295898919|gb|EFG78410.1| integral membrane protein [Mycobacterium parascrofulaceum ATCC
BAA-614]
Length=248
Score = 290 bits (742), Expect = 1e-76, Method: Compositional matrix adjust.
Identities = 150/213 (71%), Positives = 168/213 (79%), Gaps = 0/213 (0%)
Query 10 ESTLDSPVSVAREAEWQRNVRWARWLAWVSLAVLLTEGAVGLWQGIAVGSVALTGWALGG 69
EST + S+ R A W+ RWAR LAWVS+ +LTEGAVGLWQG+AVGS+ALTGWAL
Sbjct 36 ESTQVARNSLTRNAGWREAARWARRLAWVSMIAMLTEGAVGLWQGLAVGSIALTGWALSS 95
Query 70 GSEGLASAMVLWRFTGDRTWSATAEHRAQRGVAVSFWLTAPYLVAESIRHLAGEHRAETS 129
EGLASAMV+WRFTG R S +AE RAQRGVAVSFWLTAPY+ AESIRHLAGEH AETS
Sbjct 96 APEGLASAMVVWRFTGSRMLSESAERRAQRGVAVSFWLTAPYIAAESIRHLAGEHHAETS 155
Query 130 VIGIGLTAIALLLMPVLGWANHRVGERLGSGATAGEGTQNYLCAAQAAAVLLGLAITAVW 189
+IGI L LL MP+LG R+ RLGS ATAGEGTQNYLCAAQAAAVL+GLA+TA W
Sbjct 156 MIGIVLIGATLLAMPILGRTKKRLAARLGSAATAGEGTQNYLCAAQAAAVLIGLAVTAHW 215
Query 190 SNGWWIDPAIGLAIAGIAVWQGIRTWRGHGCGC 222
+ WW DPA+GLAIA +AVWQGIR WRG CGC
Sbjct 216 PSSWWFDPAVGLAIAIVAVWQGIRAWRGEDCGC 248
>gi|254821356|ref|ZP_05226357.1| putative integral membrane protein [Mycobacterium intracellulare
ATCC 13950]
Length=206
Score = 288 bits (738), Expect = 3e-76, Method: Compositional matrix adjust.
Identities = 155/205 (76%), Positives = 176/205 (86%), Gaps = 0/205 (0%)
Query 18 SVAREAEWQRNVRWARWLAWVSLAVLLTEGAVGLWQGIAVGSVALTGWALGGGSEGLASA 77
+ A +A W+R WAR LAW+SLAV+L EGAVGLWQG++VGS+ALTGWALGG SE LASA
Sbjct 2 TAAHDAGWRRGAAWARRLAWISLAVVLVEGAVGLWQGLSVGSIALTGWALGGASEALASA 61
Query 78 MVLWRFTGDRTWSATAEHRAQRGVAVSFWLTAPYLVAESIRHLAGEHRAETSVIGIGLTA 137
MV+WRF+G RT+S +AE RAQRGVAVSFWLTAPY+ AESIR L GEHRAETSVIGI LTA
Sbjct 62 MVVWRFSGARTFSPSAERRAQRGVAVSFWLTAPYIAAESIRELVGEHRAETSVIGIALTA 121
Query 138 IALLLMPVLGWANHRVGERLGSGATAGEGTQNYLCAAQAAAVLLGLAITAVWSNGWWIDP 197
+ALLLMPVLG ANHR+G RLGSGAT EG QNYLC AQAA VL+GLA TA+WS+ WWIDP
Sbjct 122 LALLLMPVLGRANHRLGARLGSGATEAEGIQNYLCGAQAAGVLIGLAATALWSSAWWIDP 181
Query 198 AIGLAIAGIAVWQGIRTWRGHGCGC 222
A+GLAIAG+AVWQG+R WRG CGC
Sbjct 182 AMGLAIAGVAVWQGVRAWRGEQCGC 206
>gi|342861475|ref|ZP_08718122.1| putative integral membrane protein [Mycobacterium colombiense
CECT 3035]
gi|342130964|gb|EGT84253.1| putative integral membrane protein [Mycobacterium colombiense
CECT 3035]
Length=218
Score = 278 bits (710), Expect = 5e-73, Method: Compositional matrix adjust.
Identities = 154/211 (73%), Positives = 172/211 (82%), Gaps = 0/211 (0%)
Query 12 TLDSPVSVAREAEWQRNVRWARWLAWVSLAVLLTEGAVGLWQGIAVGSVALTGWALGGGS 71
T + S A +A+W+R WAR LAWVSLAV+L EG VGLWQG AVGSVALTGWALGG S
Sbjct 8 TQECRGSAAHDADWRRGAGWARRLAWVSLAVVLVEGVVGLWQGFAVGSVALTGWALGGAS 67
Query 72 EGLASAMVLWRFTGDRTWSATAEHRAQRGVAVSFWLTAPYLVAESIRHLAGEHRAETSVI 131
E LASAMV+WRF+G R +SATAE RAQRGVAVSFWLTAPY+ AES+ L G AETSVI
Sbjct 68 EALASAMVVWRFSGARAFSATAERRAQRGVAVSFWLTAPYIAAESVHDLIGGRHAETSVI 127
Query 132 GIGLTAIALLLMPVLGWANHRVGERLGSGATAGEGTQNYLCAAQAAAVLLGLAITAVWSN 191
GIGLTA+AL+LMPVLG ANHR+G RLGS AT EG QNYLCAAQAA VL GLA+T +WS
Sbjct 128 GIGLTALALVLMPVLGRANHRLGTRLGSEATEAEGIQNYLCAAQAAGVLAGLAMTTLWSG 187
Query 192 GWWIDPAIGLAIAGIAVWQGIRTWRGHGCGC 222
WWIDPA+GLAIAG+AVWQG+R WRG CGC
Sbjct 188 AWWIDPAVGLAIAGVAVWQGVRAWRGEDCGC 218
>gi|333991662|ref|YP_004524276.1| hypothetical protein JDM601_3022 [Mycobacterium sp. JDM601]
gi|333487630|gb|AEF37022.1| integral membrane protein [Mycobacterium sp. JDM601]
Length=203
Score = 240 bits (612), Expect = 1e-61, Method: Compositional matrix adjust.
Identities = 125/185 (68%), Positives = 150/185 (82%), Gaps = 0/185 (0%)
Query 38 VSLAVLLTEGAVGLWQGIAVGSVALTGWALGGGSEGLASAMVLWRFTGDRTWSATAEHRA 97
VSL V+ EG VG+WQG+A GS+ALTGWALG E LA A+V+WRFTG RT S TAE RA
Sbjct 19 VSLLVVGVEGVVGIWQGLAAGSIALTGWALGAIPEALAGAIVIWRFTGARTLSETAERRA 78
Query 98 QRGVAVSFWLTAPYLVAESIRHLAGEHRAETSVIGIGLTAIALLLMPVLGWANHRVGERL 157
Q GVAVSFW+ APY+ AES+RHL +HRAE+S+IGI LT++A+L+MPVLG A R+G RL
Sbjct 79 QIGVAVSFWINAPYIAAESVRHLFSDHRAESSLIGIALTSVAVLVMPVLGRAQRRLGTRL 138
Query 158 GSGATAGEGTQNYLCAAQAAAVLLGLAITAVWSNGWWIDPAIGLAIAGIAVWQGIRTWRG 217
GS AT GEG QNYLCA QAAAVL+GL +TA W+ GWW+DP IGLA+A ++VWQG R+WRG
Sbjct 139 GSAATVGEGVQNYLCAIQAAAVLVGLTLTAQWAGGWWLDPLIGLAVAAVSVWQGFRSWRG 198
Query 218 HGCGC 222
GCGC
Sbjct 199 EGCGC 203
>gi|296164269|ref|ZP_06846857.1| integral membrane protein [Mycobacterium parascrofulaceum ATCC
BAA-614]
gi|295900378|gb|EFG79796.1| integral membrane protein [Mycobacterium parascrofulaceum ATCC
BAA-614]
Length=180
Score = 237 bits (604), Expect = 1e-60, Method: Compositional matrix adjust.
Identities = 117/180 (65%), Positives = 143/180 (80%), Gaps = 0/180 (0%)
Query 43 LLTEGAVGLWQGIAVGSVALTGWALGGGSEGLASAMVLWRFTGDRTWSATAEHRAQRGVA 102
++ EGA+GLWQG+A GSVALT WALG E +AS +V+WRF+G RT S TAE RAQRGVA
Sbjct 1 MVAEGALGLWQGVATGSVALTAWALGSAPEAMASLIVIWRFSGARTLSETAELRAQRGVA 60
Query 103 VSFWLTAPYLVAESIRHLAGEHRAETSVIGIGLTAIALLLMPVLGWANHRVGERLGSGAT 162
VSFWL+APY+ AES+ HL +H + T++IG+ LTA AL+ MP+LG A H++G RLGSGAT
Sbjct 61 VSFWLSAPYIAAESMHHLLNQHASHTTLIGVVLTAAALVQMPILGRAQHKLGARLGSGAT 120
Query 163 AGEGTQNYLCAAQAAAVLLGLAITAVWSNGWWIDPAIGLAIAGIAVWQGIRTWRGHGCGC 222
G+G QNYLCAAQAAAVLLGL +T W GWW+DPAIGL I +A+WQG R+WRG CGC
Sbjct 121 VGKGIQNYLCAAQAAAVLLGLVLTLRWPGGWWLDPAIGLCIVAVALWQGWRSWRGEDCGC 180
>gi|296170503|ref|ZP_06852090.1| integral membrane protein [Mycobacterium parascrofulaceum ATCC
BAA-614]
gi|295894855|gb|EFG74577.1| integral membrane protein [Mycobacterium parascrofulaceum ATCC
BAA-614]
Length=224
Score = 235 bits (600), Expect = 3e-60, Method: Compositional matrix adjust.
Identities = 129/202 (64%), Positives = 155/202 (77%), Gaps = 0/202 (0%)
Query 21 REAEWQRNVRWARWLAWVSLAVLLTEGAVGLWQGIAVGSVALTGWALGGGSEGLASAMVL 80
R+AEW R RWAR LAW SL + EGA+GLWQG+A GS++LTGWALG EG+AS +V+
Sbjct 23 RDAEWVRAARWARRLAWASLLWMCAEGALGLWQGLAAGSISLTGWALGSAVEGMASVIVV 82
Query 81 WRFTGDRTWSATAEHRAQRGVAVSFWLTAPYLVAESIRHLAGEHRAETSVIGIGLTAIAL 140
WRFTG R S T+E RAQRGVA+SFWL APY+ ES+R L R +T+ IGI LTA+A+
Sbjct 83 WRFTGSRALSETSERRAQRGVALSFWLIAPYIAVESVRSLLTGARPQTTFIGIALTAVAV 142
Query 141 LLMPVLGWANHRVGERLGSGATAGEGTQNYLCAAQAAAVLLGLAITAVWSNGWWIDPAIG 200
+LMP+LGWA R+G RL S AT GEGTQNYLCAAQ+AAVLL LA+ AVW GWW+DPA+G
Sbjct 143 VLMPLLGWAKRRLGTRLESRATTGEGTQNYLCAAQSAAVLLTLAVIAVWPGGWWLDPAVG 202
Query 201 LAIAGIAVWQGIRTWRGHGCGC 222
L IAG+AV +G WRG CGC
Sbjct 203 LVIAGLAVREGFEAWRGEECGC 224
>gi|120404603|ref|YP_954432.1| putative integral membrane protein [Mycobacterium vanbaalenii
PYR-1]
gi|119957421|gb|ABM14426.1| putative conserved integral membrane protein [Mycobacterium vanbaalenii
PYR-1]
Length=238
Score = 214 bits (545), Expect = 8e-54, Method: Compositional matrix adjust.
Identities = 123/206 (60%), Positives = 147/206 (72%), Gaps = 4/206 (1%)
Query 19 VAREAEWQRNVRWARWLAWVSLAVLLTEGAVGLWQGIAVGSVALTGWALGGGSEGLASAM 78
V R+A W R R AR LAWVSL + EGA+GLWQG VGS+AL GWA G EGLAS +
Sbjct 31 VVRDAGWHRAARQARLLAWVSLVWMGAEGAIGLWQGFTVGSIALIGWASGSAVEGLASII 90
Query 79 VLWRFTGDRTWSATAEHRAQRGVAVSFWLTAPYLVAESIRHLAGEHRAETSVIGIGLTAI 138
V+WRFTG T S TAE R+Q+ VAVSFWL APY+ ES+ L HRAE +V+G+ L
Sbjct 91 VVWRFTGAWTLSETAERRSQQAVAVSFWLLAPYVAIESVHDLLTGHRAEATVLGMVLAGS 150
Query 139 ALLLMPVLGWANHRVGERLGSGATAGEGTQNYLCAAQAAAVLLGLAITA----VWSNGWW 194
+L +MPVLG+A R+G RL SGATAGEG QNYLCAAQA AVLL LA+TA W+ GWW
Sbjct 151 SLAVMPVLGYAKQRLGARLASGATAGEGIQNYLCAAQAGAVLLSLAVTASWAGGWAGGWW 210
Query 195 IDPAIGLAIAGIAVWQGIRTWRGHGC 220
+DP IGL IA ++W+GI+ WRG C
Sbjct 211 LDPVIGLVIAAWSIWEGIQAWRGEDC 236
>gi|337766727|emb|CCB75438.1| putative conserved integral membrane protein [Streptomyces cattleya
NRRL 8057]
Length=235
Score = 181 bits (458), Expect = 8e-44, Method: Compositional matrix adjust.
Identities = 93/190 (49%), Positives = 130/190 (69%), Gaps = 1/190 (0%)
Query 33 RWLAWVSLAVLLTEGAVGLWQGIAVGSVALTGWALGGGSEGLASAMVLWRFTGDRTWSAT 92
+ L+W+SL + EG + + + GSVAL G+ L EGLAS +++WRF+G RT S T
Sbjct 47 KLLSWLSLGYMAAEGMIAVTATVLAGSVALLGFGLDSVIEGLASVIIVWRFSGTRTLSET 106
Query 93 AEHRAQRGVAVSFWLTAPYLVAESIRHLAGEHRAETSVIGIGLTAIALLLMPVLGWANHR 152
AE RAQ+ VAV+F+L APY+ ++I LA + TS +GIGL+ +L++MP+LG A R
Sbjct 107 AEARAQKAVAVTFFLLAPYIAYDAISTLASGEKPSTSWLGIGLSVASLIVMPLLGQAKRR 166
Query 153 VGERLGSGATAGEGTQNYLCAAQAAAVLLGLAITAVWSNGWWIDPAIGLAIAGIAVWQGI 212
+G+ L SGAT+GEGTQN LCA AAAVL+GL ++ WW+DP +GL +A +AV +G+
Sbjct 167 LGKVLDSGATSGEGTQNLLCAYLAAAVLVGLLANTLFGL-WWLDPVVGLLVAALAVREGM 225
Query 213 RTWRGHGCGC 222
WRG CGC
Sbjct 226 EAWRGEECGC 235
>gi|271968870|ref|YP_003343066.1| integral membrane protein [Streptosporangium roseum DSM 43021]
gi|270512045|gb|ACZ90323.1| integral membrane protein [Streptosporangium roseum DSM 43021]
Length=207
Score = 177 bits (450), Expect = 8e-43, Method: Compositional matrix adjust.
Identities = 99/197 (51%), Positives = 129/197 (66%), Gaps = 2/197 (1%)
Query 24 EWQRNVRWARWLAWVSLAVLLTEGAVGLWQGIAVGSVALTGWALGGGSEGLASAMVLWRF 83
EW R+ R AR L+ +LA L E A+GL G+ SVAL GW + E LAS +V+WRF
Sbjct 11 EWLRDARRARTLSLATLAWLGAESALGLAAGLGSHSVALIGWGVSSLVEALASLIVVWRF 70
Query 84 TGDRTWSATAEHRAQRGVAVSFWLTAPYLVAESIRHLAGEHRAETSVIGIGLTAIALLLM 143
TG RT SA AE +A++ VA+SFWL APYL+ L HRA SV+GI +T+++L+ M
Sbjct 71 TGSRTRSADAEDKARKAVAISFWLLAPYLLVHVAHDLEAGHRAVPSVLGIVVTSVSLVSM 130
Query 144 PVLGWANHRVGERLGSGATAGEGTQNYLCAAQAAAVLLGLAITAVWSNGWWIDPAIGLAI 203
P+LG A R+G RL S AT+GEGTQN LCA AA VL GL + A+ WW DP + + +
Sbjct 131 PLLGRAKRRLGARLHSAATSGEGTQNLLCALLAAGVLAGLGLNAI--GCWWADPVMAVLL 188
Query 204 AGIAVWQGIRTWRGHGC 220
A +AV +G + WRGH C
Sbjct 189 AAVAVREGRKAWRGHSC 205
>gi|256825296|ref|YP_003149256.1| Co/Zn/Cd cation transporter [Kytococcus sedentarius DSM 20547]
gi|256688689|gb|ACV06491.1| predicted Co/Zn/Cd cation transporter [Kytococcus sedentarius
DSM 20547]
Length=215
Score = 125 bits (315), Expect = 4e-27, Method: Compositional matrix adjust.
Identities = 78/194 (41%), Positives = 103/194 (54%), Gaps = 5/194 (2%)
Query 30 RWARWLAWVSLAVLLTEGAVGLWQGIAVGSVALTGWALGGGSEGLASAMVLWRFTGDRTW 89
R A+ LA S+ L E V L G GSVAL + L E + +VLW+F
Sbjct 22 RRAQLLALASVVYNLLEAVVALAAGTLSGSVALVAFGLDSLIEVSSGVIVLWQFRAP--V 79
Query 90 SATAEHRAQRGVAVSFWLTAPYLVAESIRHLAGEHRAETSVIGIGLTAIALLLMPVLGWA 149
E A R +AV F+ A Y+ ES+RHL G+ A TS +GI L A+++++MP L WA
Sbjct 80 PEERERLALRMMAVGFFALAAYVGVESVRHLLGDGEAGTSTVGIVLAAVSVVVMPFLSWA 139
Query 150 NHRVGERLGSGATAGEGTQNYLCAAQAAAVLLGLAITAVWSNGW-WIDPAIGLAIAGIAV 208
R G L SG+ + TQ LC +A +L+GL I GW W DP GL IA +A
Sbjct 140 QRRTGRELHSGSVVADSTQTLLCTYLSAVLLVGLLINQFL--GWTWADPVAGLVIAAVAA 197
Query 209 WQGIRTWRGHGCGC 222
+G+ WRG CGC
Sbjct 198 REGVEAWRGENCGC 211
>gi|157283867|ref|YP_001468135.1| cation efflux protein [Kineococcus radiotolerans SRS30216]
gi|151363009|gb|ABS06011.1| cation efflux protein [Kineococcus radiotolerans SRS30216]
Length=328
Score = 122 bits (306), Expect = 4e-26, Method: Compositional matrix adjust.
Identities = 76/199 (39%), Positives = 107/199 (54%), Gaps = 6/199 (3%)
Query 26 QRNV--RWARWLAWVSLAVLLTEGAVGLWQGIAVGSVALTGWALGGGSEGLASAMVLWRF 83
+R+V R R ++ + E V L G GS AL G+ L E ++A V W+F
Sbjct 34 RRDVLTRRVRMFVAATITYNVIEAVVALSAGAKAGSTALIGFGLDSVIEVSSAAAVAWQF 93
Query 84 TG-DRTWSATAEHRAQRGVAVSFWLTAPYLVAESIRHLAGEHRAETSVIGIGLTAIALLL 142
+ D EHR R +A+SF+ A Y+ ES+R L G+ AE S +G+ L A++L++
Sbjct 94 SASDHAVREAREHRTLRIIAISFFTLAAYVSVESVRALLGDGEAEQSSVGLVLAALSLMI 153
Query 143 MPVLGWANHRVGERLGSGATAGEGTQNYLCAAQAAAVLLGLAITAVWSNGW-WIDPAIGL 201
MP+L A R G LGS + + Q LC +A +L+GL + A GW W DP GL
Sbjct 154 MPLLSAAQRRAGRELGSASAVADSKQTLLCTYLSAVLLVGLGLNAAL--GWSWADPIAGL 211
Query 202 AIAGIAVWQGIRTWRGHGC 220
IA IAV +G+ WRG GC
Sbjct 212 IIAVIAVKEGLEAWRGEGC 230
>gi|311743732|ref|ZP_07717538.1| cation efflux protein [Aeromicrobium marinum DSM 15272]
gi|311312862|gb|EFQ82773.1| cation efflux protein [Aeromicrobium marinum DSM 15272]
Length=204
Score = 122 bits (305), Expect = 5e-26, Method: Compositional matrix adjust.
Identities = 78/203 (39%), Positives = 107/203 (53%), Gaps = 5/203 (2%)
Query 21 REAEWQRNVRWARWLAWVSLAVLLTEGAVGLWQGIAVGSVALTGWALGGGSEGLASAMVL 80
R E R R A+ LA VS+ E + + G+A GSVAL G+ L E + ++L
Sbjct 2 RTEERARLGRRAKLLAGVSVGYNAAEAVIAVAAGLAAGSVALVGFGLDSTVEVASGLIIL 61
Query 81 WRFTGDRTWSATAEHRAQRGVAVSFWLTAPYLVAESIRHLAGEHRAETSVIGIGLTAIAL 140
W+F+ + E A R +A+SF+ A Y+ ES+R L E S +GI L A++L
Sbjct 62 WQFS--HRVPESRERIALRLMALSFFALAGYVSVESVRSLVSRDEPEPSTVGIVLAAVSL 119
Query 141 LLMPVLGWANHRVGERLGSGATAGEGTQNYLCAAQAAAVLLGLAITAVWSNGW-WIDPAI 199
++MP L WA R G LGS + TQ LC +A +L+GL + A W GW W DP
Sbjct 120 VVMPFLSWAQRRTGRALGSDTVVADSTQTLLCTYLSAVLLVGLVLNAAW--GWSWADPLA 177
Query 200 GLAIAGIAVWQGIRTWRGHGCGC 222
GL IA +A +G WRG C C
Sbjct 178 GLVIAAVAAREGREAWRGENCAC 200
>gi|284028079|ref|YP_003378010.1| hypothetical protein Kfla_0082 [Kribbella flavida DSM 17836]
gi|283807372|gb|ADB29211.1| conserved hypothetical protein [Kribbella flavida DSM 17836]
Length=223
Score = 118 bits (296), Expect = 6e-25, Method: Compositional matrix adjust.
Identities = 81/205 (40%), Positives = 111/205 (55%), Gaps = 5/205 (2%)
Query 17 VSVAREAEWQRNVRWARWLAWVSLAVLLTEGAVGLWQGIAVGSVALTGWALGGGSEGLAS 76
+SV + ++ R A+WLA S+A L E V + G GSVAL G+ L E +
Sbjct 10 LSVGPAPDRRKLGRRAQWLAGASVAYNLVEAVVAISAGAVAGSVALIGFGLDSIVEVASG 69
Query 77 AMVLWRFTGDRTWSATAEHRAQRGVAVSFWLTAPYLVAESIRHLAGEHRAETSVIGIGLT 136
++LW+F T E RA R +AVSF+ A Y+ ES+R L + S IGIGL
Sbjct 70 LIILWQFR--HPLPETRERRALRLIAVSFFALAAYVTFESVRALTDRSSPDNSSIGIGLA 127
Query 137 AIALLLMPVLGWANHRVGERLGSGATAGEGTQNYLCAAQAAAVLLGLAITAVWSNGW-WI 195
+L++MPVL R G LGSG+ +GTQ LC +A +L GL + A GW W+
Sbjct 128 IASLIVMPVLSTLQRRTGRALGSGSVVADGTQTLLCTYLSAVLLAGLLLNATL--GWFWL 185
Query 196 DPAIGLAIAGIAVWQGIRTWRGHGC 220
DP L IA +AV +G+ W+G GC
Sbjct 186 DPVAALVIAAVAVREGVEAWQGMGC 210
>gi|84495274|ref|ZP_00994393.1| putative integral membrane protein [Janibacter sp. HTCC2649]
gi|84384767|gb|EAQ00647.1| putative integral membrane protein [Janibacter sp. HTCC2649]
Length=213
Score = 117 bits (292), Expect = 2e-24, Method: Compositional matrix adjust.
Identities = 72/194 (38%), Positives = 104/194 (54%), Gaps = 7/194 (3%)
Query 29 VRWARWLAWVSLAVLLTEGAVGLWQGIAVGSVALTGWALGGGSEGLASAMVLWRFTGDRT 88
+R A+ LA ++A + EG V + G + S AL + L E + +VLW+F
Sbjct 18 IRRAQLLAGATVACNVIEGVVAITAGRSANSSALVSFGLDSFVEVASGLIVLWQF--RHV 75
Query 89 WSATAEHRAQRGVAVSFWLTAPYLVAESIRHLAGEHRAETSVIGIGLTAIALLLMPVLGW 148
T E AQR +A +F+L A Y+ +++R L G H A+ S +G+GL ++LL+MP L
Sbjct 76 LPETRERTAQRLMAGAFFLLAAYVSVDAVRVLLGGHEADASPVGVGLAIVSLLVMPFLSR 135
Query 149 ANHRVGERLGSGATAGEGTQNYLCAAQAAAVLLGLAITAV--WSNGWWIDPAIGLAIAGI 206
A G LGSG + Q LC +A +L+GL AV W WW DP GL I +
Sbjct 136 AQRNTGRALGSGTVVSDSKQTMLCTYLSAVLLVGLLANAVLGW---WWADPLAGLVIGAV 192
Query 207 AVWQGIRTWRGHGC 220
AV +G+ +WRG C
Sbjct 193 AVREGLESWRGEAC 206
>gi|311744618|ref|ZP_07718417.1| integral membrane protein [Aeromicrobium marinum DSM 15272]
gi|311312101|gb|EFQ82019.1| integral membrane protein [Aeromicrobium marinum DSM 15272]
Length=242
Score = 115 bits (287), Expect = 6e-24, Method: Compositional matrix adjust.
Identities = 72/192 (38%), Positives = 105/192 (55%), Gaps = 5/192 (2%)
Query 30 RWARWLAWVSLAVLLTEGAVGLWQGIAVGSVALTGWALGGGSEGLASAMVLWRFTGDRTW 89
R A+ LA S+ + E + + GI GSVAL G+ L E + ++LW+F+
Sbjct 14 RRAQLLAGFSVTYNVVEAVIAISAGIVAGSVALIGFGLDSTVEVASGLIILWQFS--HRI 71
Query 90 SATAEHRAQRGVAVSFWLTAPYLVAESIRHLAGEHRAETSVIGIGLTAIALLLMPVLGWA 149
+ E +A R +A SF+ A Y+ ES R L + S +GI L A++L++MP + +A
Sbjct 72 PQSREQQALRLLAFSFFALAAYVGFESARALIFGSDPDASTVGIILAAVSLVVMPFVSYA 131
Query 150 NHRVGERLGSGATAGEGTQNYLCAAQAAAVLLGLAITAVWSNGW-WIDPAIGLAIAGIAV 208
R G+ LGS A +GTQ LC +A +L+GL A GW W DP GL IA IA+
Sbjct 132 QRRTGKALGSNAVYADGTQTLLCTYLSAVLLVGLVANATL--GWTWADPVAGLIIAVIAL 189
Query 209 WQGIRTWRGHGC 220
+G+ W+G GC
Sbjct 190 REGLEAWKGDGC 201
>gi|118473825|ref|YP_889838.1| integral membrane protein [Mycobacterium smegmatis str. MC2 155]
gi|118175112|gb|ABK76008.1| integral membrane protein [Mycobacterium smegmatis str. MC2 155]
Length=221
Score = 114 bits (284), Expect = 1e-23, Method: Compositional matrix adjust.
Identities = 76/207 (37%), Positives = 110/207 (54%), Gaps = 8/207 (3%)
Query 15 SPVSVAREAEWQRNVRWARWLAWVSLAVLLTEGAVGLWQGIAVGSVALTGWALGGGSEGL 74
S ++ R A R +R ++ + E V L +G V S AL G+ L E
Sbjct 18 SKLTPTRRAVLARRIRM---FVAATITYNVIEAVVALTEGARVSSTALIGFGLDSVIEVS 74
Query 75 ASAMVLWRFTGDRTWSATAEHRAQRGVAVSFWLTAPYLVAESIRHLAGEHRAETSVIGIG 134
++A V W+F G R A E A R VA SF+ A Y+ ++IR L G A+ S IGI
Sbjct 75 SAAAVAWQFAG-RDPEAR-EKVALRIVAFSFFGLATYVAVDAIRSLLGIGEAQHSTIGIA 132
Query 135 LTAIALLLMPVLGWANHRVGERLGSGATAGEGTQNYLCAAQAAAVLLGLAITAVWSNGW- 193
L A++L++MPVL +A R G LGS + + Q LC +A +L+GL + +++ GW
Sbjct 133 LAALSLVIMPVLSYAQRRAGRELGSLSAVADSKQTLLCTYLSAVLLVGLLLNSIF--GWS 190
Query 194 WIDPAIGLAIAGIAVWQGIRTWRGHGC 220
W DP GL IA +AV +G+ W+G C
Sbjct 191 WADPIAGLVIAAVAVREGLEAWKGDTC 217
>gi|182437562|ref|YP_001825281.1| putative integral membrane protein [Streptomyces griseus subsp.
griseus NBRC 13350]
gi|326778217|ref|ZP_08237482.1| cation efflux protein [Streptomyces cf. griseus XylebKG-1]
gi|178466078|dbj|BAG20598.1| putative integral membrane protein [Streptomyces griseus subsp.
griseus NBRC 13350]
gi|326658550|gb|EGE43396.1| cation efflux protein [Streptomyces griseus XylebKG-1]
Length=224
Score = 108 bits (271), Expect = 4e-22, Method: Compositional matrix adjust.
Identities = 74/207 (36%), Positives = 105/207 (51%), Gaps = 8/207 (3%)
Query 16 PVSVAREAEWQRNVRWARWLAWVSLAVLLTEGAVGLWQGIAVGSVALTGWALGGGSEGLA 75
P REA +R R L V++A + E V L G S AL G+ L E +
Sbjct 8 PSPARREALARR----IRLLVAVTIAYNVVEAMVALTAGTIASSSALIGFGLDSVIEVSS 63
Query 76 SAMVLWRFTG-DRTWSATAEHRAQRGVAVSFWLTAPYLVAESIRHLAGEHRAETSVIGIG 134
+A V W+F+ + T E A R ++VSF+ A Y+ +++R L G A+ S +GI
Sbjct 64 AAAVAWQFSAREHTVREAREKAALRIISVSFFALAAYVAVDAVRALTGTGEADPSPVGIV 123
Query 135 LTAIALLLMPVLGWANHRVGERLGSGATAGEGTQNYLCAAQAAAVLLGLAITAVWSNGW- 193
+ A++L +MP L A R G +GS + + Q LC +A +L GL + A GW
Sbjct 124 IAALSLAVMPFLSAAQRRAGREIGSASAVADSKQTLLCTYLSAVLLAGLLLNATL--GWT 181
Query 194 WIDPAIGLAIAGIAVWQGIRTWRGHGC 220
W DP L IAG+AV +G WRG GC
Sbjct 182 WADPVAALVIAGLAVKEGREAWRGRGC 208
>gi|169629689|ref|YP_001703338.1| integral membrane protein [Mycobacterium abscessus ATCC 19977]
gi|169241656|emb|CAM62684.1| Probable conserved integral membrane protein [Mycobacterium abscessus]
Length=225
Score = 108 bits (271), Expect = 4e-22, Method: Compositional matrix adjust.
Identities = 75/201 (38%), Positives = 109/201 (55%), Gaps = 7/201 (3%)
Query 23 AEWQRNV--RWARWLAWVSLAVLLTEGAVGLWQGIAVGSVALTGWALGGGSEGLASAMVL 80
A+ +R+V R R+ ++A + E V L +G V S AL G+ L E ++A V
Sbjct 4 AQQRRDVLNRRIRFFVVATIAYNVIEAIVALTEGSRVSSTALIGFGLDSVIEVSSAAAVA 63
Query 81 WRFTGDRTWSATAEHRAQRGVAVSFWLTAPYLVAESIRHLAGEHRAETSVIGIGLTAIAL 140
W+F+ T E A R +A SF+ A Y+ +S+R LAG +A S +GI L A +L
Sbjct 64 WQFSAKDP--ETREKVALRVIAFSFFALAAYVAVDSVRALAGLDQARQSTVGIALAAASL 121
Query 141 LLMPVLGWANHRVGERLGSGATAGEGTQNYLCAAQAAAVLLGLAITAVWSNGW-WIDPAI 199
++MP L WA R G LGS + + Q LC +A +L GL + ++++ W W DP
Sbjct 122 VIMPALSWAQRRTGRELGSASAVADSKQTLLCTYLSAVLLAGLLVNSLFA--WSWADPIA 179
Query 200 GLAIAGIAVWQGIRTWRGHGC 220
LAIA IAV +G+ WRG C
Sbjct 180 ALAIAVIAVREGMNAWRGESC 200
>gi|296268434|ref|YP_003651066.1| cation efflux protein [Thermobispora bispora DSM 43833]
gi|296091221|gb|ADG87173.1| cation efflux protein [Thermobispora bispora DSM 43833]
Length=240
Score = 108 bits (271), Expect = 5e-22, Method: Compositional matrix adjust.
Identities = 69/194 (36%), Positives = 103/194 (54%), Gaps = 4/194 (2%)
Query 29 VRWARWLAWVSLAVLLTEGAVGLWQGIAVGSVALTGWALGGGSEGLASAMVLWRFTG-DR 87
+R R L +++ + E V + G S AL + L E ++A V W+F+ D
Sbjct 17 MRRVRLLVAATISYNVIEAVVAIAAGSVASSGALVAFGLDSVIEVASAAAVAWQFSARDP 76
Query 88 TWSATAEHRAQRGVAVSFWLTAPYLVAESIRHLAGEHRAETSVIGIGLTAIALLLMPVLG 147
E RA R +A+SF+ A Y+ +S+ L G AE S G+ L A++L++MPVL
Sbjct 77 EVVERRERRALRMIALSFFALALYVSVDSVAALLGGGEAEHSTPGLILAALSLVIMPVLS 136
Query 148 WANHRVGERLGSGATAGEGTQNYLCAAQAAAVLLGLAITAVWSNGW-WIDPAIGLAIAGI 206
+A R G LGS + + Q LC +A +L GLA+ +++ GW W DP L IAG+
Sbjct 137 YAQRRAGRELGSASAVADSKQTLLCTYLSAVLLAGLAVNSLF--GWAWADPVAALVIAGV 194
Query 207 AVWQGIRTWRGHGC 220
AV +G+ WRG C
Sbjct 195 AVKEGLEAWRGDAC 208
>gi|226309136|ref|YP_002769096.1| hypothetical protein RER_56490 [Rhodococcus erythropolis PR4]
gi|226188253|dbj|BAH36357.1| conserved hypothetical membrane protein [Rhodococcus erythropolis
PR4]
Length=223
Score = 106 bits (265), Expect = 2e-21, Method: Compositional matrix adjust.
Identities = 72/205 (36%), Positives = 106/205 (52%), Gaps = 8/205 (3%)
Query 17 VSVAREAEWQRNVRWARWLAWVSLAVLLTEGAVGLWQGIAVGSVALTGWALGGGSEGLAS 76
+S AR A R +R ++++ + E + L +G V S AL G+ L E ++
Sbjct 10 LSTARRALLSRRIRI---FVAITISYNVVEAVIALAEGTRVSSAALFGFGLDSVIEVSSA 66
Query 77 AMVLWRFTGDRTWSATAEHRAQRGVAVSFWLTAPYLVAESIRHLAGEHRAETSVIGIGLT 136
A V W+F+ S E A R +A SF+ A Y+ ++IR L G A+ + +GI L
Sbjct 67 AAVAWQFSAPDPTSR--EKTALRVIAFSFFGLAAYVSFDAIRSLFGLGEAQHTSVGIVLA 124
Query 137 AIALLLMPVLGWANHRVGERLGSGATAGEGTQNYLCAAQAAAVLLGLAITAVWSNGW-WI 195
A +L +MP L +A R G LGS + + Q LC +A +L+GL + +V GW W
Sbjct 125 AASLAIMPALSYAQRRAGRELGSLSAVADSKQTLLCTYLSAVLLVGLLLNSVL--GWSWA 182
Query 196 DPAIGLAIAGIAVWQGIRTWRGHGC 220
DP L IA IAV +GI W+G C
Sbjct 183 DPIAALVIAVIAVKEGINAWKGDPC 207
>gi|116662405|ref|YP_829458.1| cation efflux protein [Arthrobacter sp. FB24]
gi|116613184|gb|ABK05877.1| cation efflux protein [Arthrobacter sp. FB24]
Length=296
Score = 106 bits (265), Expect = 2e-21, Method: Compositional matrix adjust.
Identities = 71/212 (34%), Positives = 104/212 (50%), Gaps = 10/212 (4%)
Query 11 STLDSPVSVAREAEWQRNVRWARWLAWVSLAVLLTEGAVGLWQGIAVGSVALTGWALGGG 70
+TL + + +R A R +R A ++ L E V LW G S AL G+ L
Sbjct 3 TTLQTVPTASRHAVLSRRIRL---FAAATITYNLVEAVVALWAGNMADSSALIGFGLDSV 59
Query 71 SEGLASAMVLWRFTGDRTWSATAEHRAQRGVAVSFWLTAPYLVAESIRHLAGEHRAETSV 130
E ++ + W+F+ EH R +A+SF+ A ++ +S+R L G A+ S
Sbjct 60 IEVASAVALSWQFSAKD--PERREHLTLRIIAISFFALALFVSVDSVRSLTGGGEAQHST 117
Query 131 IGIGLTAIALLLMPVLGWANHRVGERLGSGATAGEGTQNYLCAAQAAAVLLGLAITAV-- 188
GI + A++L +MPVL W R G LGS + Q LC +A +L+GL + +
Sbjct 118 PGIVIAALSLAIMPVLSWLQRRAGRELGSKTAVADSKQTLLCTYLSAVLLVGLVLNSTLG 177
Query 189 WSNGWWIDPAIGLAIAGIAVWQGIRTWRGHGC 220
W WW D L IAGIAV +GI W+G C
Sbjct 178 W---WWADAGAALVIAGIAVREGINAWKGDVC 206
>gi|317125775|ref|YP_004099887.1| cation efflux protein [Intrasporangium calvum DSM 43043]
gi|315589863|gb|ADU49160.1| cation efflux protein [Intrasporangium calvum DSM 43043]
Length=245
Score = 106 bits (264), Expect = 3e-21, Method: Compositional matrix adjust.
Identities = 74/208 (36%), Positives = 109/208 (53%), Gaps = 6/208 (2%)
Query 15 SPVSVAREAEWQRNVRWARWLAWVSLAVLLTEGAVGLWQGIAVGSVALTGWALGGGSEGL 74
+P S+A + E +R R A LA ++A + EG VG+ GI G V+L G+ L G E
Sbjct 20 TPSSMA-DPETERLTRRALRLAQFTVAYNVVEGVVGITAGIMAGLVSLVGFGLDSGIESA 78
Query 75 ASAMVLWRFTGD-RTWSAT--AEHRAQRGVAVSFWLTAPYLVAESIRHLAGEHRAETSVI 131
A+ +V R R A E RA RGVAV+F+L A Y+V E +R L + S++
Sbjct 79 AAVLVGLRLAARLRHGQADERKERRALRGVAVTFFLLAAYVVVEGVRSLIRGEEPDQSLV 138
Query 132 GIGLTAIALLLMPVLGWANHRVGERL-GSGATAGEGTQNYLCAAQAAAVLLGLAITAVWS 190
GI L + +L++MPVL A RVG L G + + +C + + LLGL + ++ +
Sbjct 139 GIILLSTSLIVMPVLAAAKQRVGRALGGDRLILADAAETKICMLLSVSTLLGLGLYSL-T 197
Query 191 NGWWIDPAIGLAIAGIAVWQGIRTWRGH 218
W+DP G IA A+ +G W G
Sbjct 198 GAAWLDPVAGFVIAVFALNEGREAWEGE 225
>gi|119960546|ref|YP_947144.1| cation efflux family protein [Arthrobacter aurescens TC1]
gi|119947405|gb|ABM06316.1| putative cation efflux family protein [Arthrobacter aurescens
TC1]
Length=243
Score = 105 bits (261), Expect = 7e-21, Method: Compositional matrix adjust.
Identities = 66/193 (35%), Positives = 96/193 (50%), Gaps = 7/193 (3%)
Query 30 RWARWLAWVSLAVLLTEGAVGLWQGIAVGSVALTGWALGGGSEGLASAMVLWRFTGDRTW 89
R R A ++ + E LW G S AL G+ L E ++ + W+F+
Sbjct 18 RRIRLFAAATITYNVIEAVAALWAGGVADSSALIGFGLDSVIEVTSALALSWQFSAKD-- 75
Query 90 SATAEHRAQRGVAVSFWLTAPYLVAESIRHLAGEHRAETSVIGIGLTAIALLLMPVLGWA 149
EH R +AVSF++ A ++ +++R L G A+ S GI + A++L +MPVL WA
Sbjct 76 PERREHLTLRIIAVSFFVLAAFVTVDAVRSLLGAGEAQHSTPGIVIAALSLAIMPVLSWA 135
Query 150 NHRVGERLGSGATAGEGTQNYLCAAQAAAVLLGLAITAV--WSNGWWIDPAIGLAIAGIA 207
R G LGS + Q LC +A +L+GL + + W WW D L IAGIA
Sbjct 136 QRRAGRELGSRTAVADSKQTLLCTYLSAVLLIGLVLNSTLGW---WWADAGAALVIAGIA 192
Query 208 VWQGIRTWRGHGC 220
V +GI W+G C
Sbjct 193 VREGINAWKGEAC 205
>gi|111021225|ref|YP_704197.1| hypothetical protein RHA1_ro04248 [Rhodococcus jostii RHA1]
gi|110820755|gb|ABG96039.1| possible membrane protein [Rhodococcus jostii RHA1]
Length=344
Score = 104 bits (259), Expect = 1e-20, Method: Compositional matrix adjust.
Identities = 72/203 (36%), Positives = 104/203 (52%), Gaps = 7/203 (3%)
Query 21 REAEWQRNV--RWARWLAWVSLAVLLTEGAVGLWQGIAVGSVALTGWALGGGSEGLASAM 78
R + +R V R R+ +++ + E V L +G V S AL G+ L E ++A
Sbjct 125 RPSGERRQVLSRRIRFFVAATISYNVIEAIVALTEGARVSSTALIGFGLDSVIEVSSAAG 184
Query 79 VLWRFTGDRTWSATAEHRAQRGVAVSFWLTAPYLVAESIRHLAGEHRAETSVIGIGLTAI 138
V W+F G S E R +A SF+ A Y+ +++R L G A+ S +GI L A
Sbjct 185 VAWQFAGRDPESR--EKVTLRVIAFSFFGLAAYVSVDAVRSLLGVGEAQHSTVGIALAAA 242
Query 139 ALLLMPVLGWANHRVGERLGSGATAGEGTQNYLCAAQAAAVLLGLAITAVWSNGW-WIDP 197
+L +MPVL WA R G LGS + + Q LC +A +L+GL + + GW W DP
Sbjct 243 SLAVMPVLSWAQRRAGRELGSLSAVADSKQTLLCTYLSAVLLVGLLLNSTL--GWSWADP 300
Query 198 AIGLAIAGIAVWQGIRTWRGHGC 220
L IA IAV +G+ W+G C
Sbjct 301 IAALVIAVIAVREGVDAWKGDTC 323
>gi|291299242|ref|YP_003510520.1| cation efflux protein [Stackebrandtia nassauensis DSM 44728]
gi|290568462|gb|ADD41427.1| cation efflux protein [Stackebrandtia nassauensis DSM 44728]
Length=221
Score = 103 bits (256), Expect = 2e-20, Method: Compositional matrix adjust.
Identities = 73/201 (37%), Positives = 113/201 (57%), Gaps = 9/201 (4%)
Query 21 REAEWQRNVRWARWLAWVSLAVLLTEGAVGLWQGIAVGSVALTGWALGGGSEGLASAMVL 80
RE +R++R LA+ ++ + EG V + G S AL G+ + G E ++ +V+
Sbjct 12 RERLNRRSLR----LAYATVGYNVAEGVVAIIAGAVASSTALIGFGIDSGIEVSSATVVI 67
Query 81 WRFTGDRTWSATAEHRAQRGVAVSFWLTAPYLVAESIRHLAGEHRAETSVIGIGLTAIAL 140
W+F T E A + +AVSF+ A ++ +S+R L A+ S +GIGL A+++
Sbjct 68 WQFRS--TLPEARERLALKLIAVSFFALAAWVGFDSVRSLLVGEAAQPSGVGIGLAAVSV 125
Query 141 LLMPVLGWANHRVGERLGSGATAGEGTQNYLCAAQAAAVLLGLAITAVWSNGW-WIDPAI 199
++MP+L WA R G LGS + + TQ LC +A +L+GL + AV GW W DPA
Sbjct 126 VVMPLLVWAKRRTGRELGSASVEADSTQTLLCTYLSAVLLIGLTLNAVL--GWSWADPAA 183
Query 200 GLAIAGIAVWQGIRTWRGHGC 220
L IA +AV +G++ WRG C
Sbjct 184 ALVIAAVAVREGVQAWRGEAC 204
>gi|328883501|emb|CCA56740.1| probable integral membrane protein [Streptomyces venezuelae ATCC
10712]
Length=222
Score = 103 bits (256), Expect = 2e-20, Method: Compositional matrix adjust.
Identities = 75/199 (38%), Positives = 101/199 (51%), Gaps = 6/199 (3%)
Query 26 QRNV--RWARWLAWVSLAVLLTEGAVGLWQGIAVGSVALTGWALGGGSEGLASAMVLWRF 83
+R+V R R L ++ + E V L G S AL G+ L E ++A V W+F
Sbjct 15 RRDVLTRRIRLLVAATITYNVIEAIVALTAGTLASSTALIGFGLDSVIEVSSAAAVAWQF 74
Query 84 TG-DRTWSATAEHRAQRGVAVSFWLTAPYLVAESIRHLAGEHRAETSVIGIGLTAIALLL 142
+ D E R R +AVSF+ A Y+ +++R L G AE SV GI + A++L +
Sbjct 75 SARDHAVREAREQRTLRIIAVSFFALAAYVTVDAVRALTGTGEAERSVPGIVIAALSLAV 134
Query 143 MPVLGWANHRVGERLGSGATAGEGTQNYLCAAQAAAVLLGLAITAVWSNGW-WIDPAIGL 201
MP L A R G LGS + + Q LC +A +LLGL + A GW W DP L
Sbjct 135 MPFLSAAQRRAGRELGSASAVADSKQTLLCTYLSAVLLLGLVLNATL--GWSWADPIAAL 192
Query 202 AIAGIAVWQGIRTWRGHGC 220
IA IAV +G WRG GC
Sbjct 193 LIAAIAVKEGRDAWRGEGC 211
>gi|331694410|ref|YP_004330649.1| cation efflux protein [Pseudonocardia dioxanivorans CB1190]
gi|326949099|gb|AEA22796.1| cation efflux protein [Pseudonocardia dioxanivorans CB1190]
Length=217
Score = 102 bits (255), Expect = 3e-20, Method: Compositional matrix adjust.
Identities = 68/169 (41%), Positives = 87/169 (52%), Gaps = 7/169 (4%)
Query 54 GIAVGSVALTGWALGGGSEGLASAMVLWRFTGDRTWSATAEHRAQRGVAVSFWLTAPYLV 113
G S+AL G+ L E ++A V W+F G E A R +A SF A Y+
Sbjct 38 GTVASSIALVGFGLDSVIEVSSAAAVAWQFAGPDPQRR--ERVALRLIAGSFVALACYVS 95
Query 114 AESIRHLAGEHRAETSVIGIGLTAIALLLMPVLGWANHRVGERLGSGATAGEGTQNYLCA 173
ESIR LAG E S +GI L A+++L+MP L WA R G LGS + + Q LC
Sbjct 96 VESIRGLAGAAEPERSPVGIALVALSVLVMPFLSWAQRRAGRELGSSSAVADSRQTLLCT 155
Query 174 AQAAAVLLGLAITAV--WSNGWWIDPAIGLAIAGIAVWQGIRTWRGHGC 220
+AAVL GL + A W WW DP GL IA +A+ + WRG C
Sbjct 156 YLSAAVLAGLLLNATLGW---WWADPVAGLVIAVLALREARNAWRGELC 201
>gi|336179230|ref|YP_004584605.1| cation efflux protein [Frankia symbiont of Datisca glomerata]
gi|334860210|gb|AEH10684.1| cation efflux protein [Frankia symbiont of Datisca glomerata]
Length=235
Score = 102 bits (254), Expect = 4e-20, Method: Compositional matrix adjust.
Identities = 74/208 (36%), Positives = 102/208 (50%), Gaps = 8/208 (3%)
Query 15 SPVSVAREAEWQRNVRWARWLAWVSLAVLLTEGAVGLWQGIAVGSVALTGWALGGGSEGL 74
SP S AR R +R+ L ++ + E V L G S AL G+ L E
Sbjct 7 SP-SPARRTALTRRIRF---LVAATITYNVIEAVVALTLGTIASSTALIGFGLDSVIEVS 62
Query 75 ASAMVLWRFTG-DRTWSATAEHRAQRGVAVSFWLTAPYLVAESIRHLAGEHRAETSVIGI 133
++ V W+F+ D T E R +AVSF+ A Y +++R LAG +A+ S+ GI
Sbjct 63 SATAVAWQFSATDHTSRQAREKTTLRIIAVSFFALAAYATVDAVRMLAGTGKADGSLPGI 122
Query 134 GLTAIALLLMPVLGWANHRVGERLGSGATAGEGTQNYLCAAQAAAVLLGLAITAVWSNGW 193
L A++L +MP L A R G LGS + + Q LC +A +L+GL TA + W
Sbjct 123 VLAALSLAVMPFLSTAQRRAGRELGSASAIADSKQTLLCTYLSAVLLIGL--TANATLDW 180
Query 194 -WIDPAIGLAIAGIAVWQGIRTWRGHGC 220
W DP L IA IAV +G W G C
Sbjct 181 AWTDPITALVIAVIAVKEGRNAWAGDTC 208
>gi|145224482|ref|YP_001135160.1| Co/Zn/Cd cation transporters-like protein [Mycobacterium gilvum
PYR-GCK]
gi|145216968|gb|ABP46372.1| Co/Zn/Cd cation transporters-like protein [Mycobacterium gilvum
PYR-GCK]
Length=229
Score = 102 bits (254), Expect = 5e-20, Method: Compositional matrix adjust.
Identities = 75/205 (37%), Positives = 101/205 (50%), Gaps = 8/205 (3%)
Query 17 VSVAREAEWQRNVRWARWLAWVSLAVLLTEGAVGLWQGIAVGSVALTGWALGGGSEGLAS 76
VS AR A R VR ++ L E V + G S AL G+ L E ++
Sbjct 31 VSPARRAVLTRRVRL---FVLATITYNLIEAVVAISAGTIASSAALIGFGLDSLIEVASA 87
Query 77 AMVLWRFTGDRTWSATAEHRAQRGVAVSFWLTAPYLVAESIRHLAGEHRAETSVIGIGLT 136
V W+F G E A R +AVSF+ A Y+ ES R L G A S GI L
Sbjct 88 TAVAWQFAGRDPEER--ERTALRIIAVSFFALATYVTVESARALFGAAEAAPSPAGIVLA 145
Query 137 AIALLLMPVLGWANHRVGERLGSGATAGEGTQNYLCAAQAAAVLLGLAITAVWSNGW-WI 195
A++L +MP L +A R G LGS + + Q LC + +L+GL + A++ GW W
Sbjct 146 AVSLAVMPFLSYAQRRAGRELGSASAVADSKQTLLCTYLSGVLLVGLLLNALF--GWSWA 203
Query 196 DPAIGLAIAGIAVWQGIRTWRGHGC 220
DP + L IAG+AV +G + WRG C
Sbjct 204 DPIVALVIAGVAVKEGRQAWRGEHC 228
>gi|120404892|ref|YP_954721.1| cation efflux protein [Mycobacterium vanbaalenii PYR-1]
gi|119957710|gb|ABM14715.1| cation efflux protein [Mycobacterium vanbaalenii PYR-1]
Length=202
Score = 101 bits (252), Expect = 8e-20, Method: Compositional matrix adjust.
Identities = 67/192 (35%), Positives = 96/192 (50%), Gaps = 5/192 (2%)
Query 30 RWARWLAWVSLAVLLTEGAVGLWQGIAVGSVALTGWALGGGSEGLASAMVLWRFTGDRTW 89
R R+L ++ + E V L +G V S AL G+ L E ++A V W+F+
Sbjct 13 RRIRFLVAATITYNVIEAVVALAEGSRVSSAALVGFGLDSVVEVSSAAAVAWQFSA--VD 70
Query 90 SATAEHRAQRGVAVSFWLTAPYLVAESIRHLAGEHRAETSVIGIGLTAIALLLMPVLGWA 149
T E A R +A SF+ A Y+ ++ L G + IGI L ++L +MP L A
Sbjct 71 PETREKAALRFIAFSFFALACYVAVDAALSLVGVREPRPTPIGIVLAGLSLAVMPTLSLA 130
Query 150 NHRVGERLGSGATAGEGTQNYLCAAQAAAVLLGLAITAVWSNGW-WIDPAIGLAIAGIAV 208
R G LGS + + Q LCA +A +L+GL + A+ GW W DP L IA +AV
Sbjct 131 QRRAGRELGSRSAVADSKQTLLCAYLSAVLLVGLVLHALL--GWTWADPVAALGIAALAV 188
Query 209 WQGIRTWRGHGC 220
+G+ WRG C
Sbjct 189 REGLEAWRGDPC 200
>gi|126436473|ref|YP_001072164.1| hypothetical protein Mjls_3897 [Mycobacterium sp. JLS]
gi|126436480|ref|YP_001072171.1| hypothetical protein Mjls_3905 [Mycobacterium sp. JLS]
gi|126236273|gb|ABN99673.1| conserved hypothetical protein [Mycobacterium sp. JLS]
gi|126236280|gb|ABN99680.1| conserved hypothetical protein [Mycobacterium sp. JLS]
Length=214
Score = 100 bits (248), Expect = 2e-19, Method: Compositional matrix adjust.
Identities = 63/210 (30%), Positives = 105/210 (50%), Gaps = 6/210 (2%)
Query 13 LDSPVSVAREAEWQRNVRWARWLAWVSLAVLLTEGAVGLWQGIAVGSVALTGWALGGGSE 72
+ +P + AE +R R LA ++ + EGAV + G+ G V++ G+ + G E
Sbjct 1 MSTPDTTLTAAETERLTRRGLRLAQFTVGYNVIEGAVAITAGLMAGLVSVVGFGIDSGIE 60
Query 73 GLASAMVLWRFTGDRTWSATAEHRAQRG----VAVSFWLTAPYLVAESIRHLAGEHRAET 128
+A+ +V R + R A+ R +R VA +F+L A Y+ E IR L G E+
Sbjct 61 SIAAVLVALRLSA-RLRHGHADERKERIALKLVASTFFLLAGYVTIEGIRSLIGGEEPES 119
Query 129 SVIGIGLTAIALLLMPVLGWANHRVGERLGSGATAGEGTQNYLCAAQAAAVLLGLAITAV 188
S + IGL ++++MPVL A +VG +L + + +C + + LLG+ + A+
Sbjct 120 SPLAIGLLVASIIVMPVLAAAKKKVGTQLKDNLILADAAETKICVLLSISTLLGVGLFAL 179
Query 189 WSNGWWIDPAIGLAIAGIAVWQGIRTWRGH 218
+ W+DP G IA A+ +G W G
Sbjct 180 -TGAAWLDPVAGFVIAAFAIHEGREAWEGE 208
>gi|86741408|ref|YP_481808.1| putative integral membrane protein [Frankia sp. CcI3]
gi|86568270|gb|ABD12079.1| putative integral membrane protein [Frankia sp. CcI3]
Length=238
Score = 99.4 bits (246), Expect = 3e-19, Method: Compositional matrix adjust.
Identities = 75/193 (39%), Positives = 97/193 (51%), Gaps = 4/193 (2%)
Query 30 RWARWLAWVSLAVLLTEGAVGLWQGIAVGSVALTGWALGGGSEGLASAMVLWRFTG-DRT 88
R R L V++A + E V L G A S AL G+ L E ++A V+W+F+ D
Sbjct 19 RRIRLLVGVTIAYNVVEAVVALTLGAAASSTALIGFGLDSVIEVSSAAAVVWQFSASDHA 78
Query 89 WSATAEHRAQRGVAVSFWLTAPYLVAESIRHLAGEHRAETSVIGIGLTAIALLLMPVLGW 148
E RA R +AVSF A Y+ +R L G A+ SV GI L A++L +MP L
Sbjct 79 VREARERRALRIIAVSFVALAVYVTVNVVRSLTGRQDADGSVPGIVLAAVSLAVMPFLSA 138
Query 149 ANHRVGERLGSGATAGEGTQNYLCAAQAAAVLLGLAITAVWSNGW-WIDPAIGLAIAGIA 207
A R G LGS + + Q LC +A +L GL + A GW W DP L IA IA
Sbjct 139 AQRRTGRELGSASAVADSKQTLLCTYLSAVLLAGLLLNATL--GWSWADPLAALVIAVIA 196
Query 208 VWQGIRTWRGHGC 220
V +G WRG C
Sbjct 197 VKEGRDAWRGDVC 209
>gi|254411318|ref|ZP_05025095.1| cation efflux family protein [Microcoleus chthonoplastes PCC
7420]
gi|196181819|gb|EDX76806.1| cation efflux family protein [Microcoleus chthonoplastes PCC
7420]
Length=203
Score = 99.4 bits (246), Expect = 4e-19, Method: Compositional matrix adjust.
Identities = 54/187 (29%), Positives = 98/187 (53%), Gaps = 5/187 (2%)
Query 34 WLAWVSLAVLLTEGAVGLWQGIAVGSVALTGWALGGGSEGLASAMVLWRFTGDRTWSATA 93
+L + ++ + E V + G S+AL G+ L E L+ +++WR + + + +
Sbjct 10 YLEYFTVGYNILEAVVSILLGAINNSIALIGFGLDSIVESLSGCILIWRLSQHQNLTPES 69
Query 94 EHRAQRG----VAVSFWLTAPYLVAESIRHLAGEHRAETSVIGIGLTAIALLLMPVLGWA 149
E + +R VA++F+L A Y+ ES+R L + E S +GI L ++L++MP+L W
Sbjct 70 EAKIERQATQFVAITFFLMAGYIGFESLRKLINQDVPEPSFMGILLALLSLMIMPLLAWQ 129
Query 150 NHRVGERLGSGATAGEGTQNYLCAAQAAAVLLGLAITAVWSNGWWIDPAIGLAIAGIAVW 209
++VG++L S A + + +C+ + A+LLGL + W + W DP G I +
Sbjct 130 KNKVGKQLNSKALIADAKETLVCSFLSVALLLGL-VGNYWFSFWQADPFAGFIIVFYLIK 188
Query 210 QGIRTWR 216
+G W
Sbjct 189 EGWEVWE 195
>gi|327309763|ref|YP_004336661.1| cation efflux protein [Pseudonocardia dioxanivorans CB1190]
gi|326955098|gb|AEA28794.1| cation efflux protein [Pseudonocardia dioxanivorans CB1190]
Length=240
Score = 98.2 bits (243), Expect = 7e-19, Method: Compositional matrix adjust.
Identities = 71/199 (36%), Positives = 100/199 (51%), Gaps = 6/199 (3%)
Query 26 QRNV--RWARWLAWVSLAVLLTEGAVGLWQGIAVGSVALTGWALGGGSEGLASAMVLWRF 83
+R+V R R L ++ + E V + G S AL G+ L E ++A V W+F
Sbjct 15 RRDVLARRIRLLVAATITYNVIEAVVAITAGTLASSTALIGFGLDSVIEVSSAAAVAWQF 74
Query 84 TG-DRTWSATAEHRAQRGVAVSFWLTAPYLVAESIRHLAGEHRAETSVIGIGLTAIALLL 142
+ D E R R +AVSF+ A Y+ +++R L G AE S+ GI + A++L +
Sbjct 75 SARDHAVREAREQRTLRIIAVSFFALAAYVSVDAVRALTGTGEAERSIPGIVIAALSLAI 134
Query 143 MPVLGWANHRVGERLGSGATAGEGTQNYLCAAQAAAVLLGLAITAVWSNGW-WIDPAIGL 201
MP L A R G LGS + + Q LC +A +LLGL + A GW W DP L
Sbjct 135 MPFLSAAQRRAGRELGSASAVADSKQTLLCTYLSAVLLLGLVLNATL--GWSWADPIAAL 192
Query 202 AIAGIAVWQGIRTWRGHGC 220
IA IA +G W+G GC
Sbjct 193 VIAAIAFKEGRDAWQGKGC 211
>gi|148272396|ref|YP_001221957.1| CDF family cation efflux protein [Clavibacter michiganensis subsp.
michiganensis NCPPB 382]
gi|147830326|emb|CAN01260.1| putative cation efflux protein, CDF family [Clavibacter michiganensis
subsp. michiganensis NCPPB 382]
Length=232
Score = 98.2 bits (243), Expect = 8e-19, Method: Compositional matrix adjust.
Identities = 67/177 (38%), Positives = 91/177 (52%), Gaps = 7/177 (3%)
Query 46 EGAVGLWQGIAVGSVALTGWALGGGSEGLASAMVLWRFTGDRTWSATAEHRAQRGVAVSF 105
E V L G+ S AL + L E LA++ V W+F+ + E A R +AVSF
Sbjct 36 EAVVALTAGVVASSTALVAFGLDSIVEVLAASAVAWQFSAPDPEAR--ERTALRLIAVSF 93
Query 106 WLTAPYLVAESIRHLAGEHRAETSVIGIGLTAIALLLMPVLGWANHRVGERLGSGATAGE 165
A Y+ +++ LAG A S GI L A++L +MP L R G LGS + +
Sbjct 94 LGLAAYVSVDAVLALAGGSEARPSTTGIVLAALSLAVMPALSLLERRTGTELGSASAVAD 153
Query 166 GTQNYLCAAQAAAVLLGLAITA--VWSNGWWIDPAIGLAIAGIAVWQGIRTWRGHGC 220
Q +CA +AA+L+GL + A W WW DP GLAIA AV +G+ WRG C
Sbjct 154 SRQTLVCAWLSAALLVGLLLDAGLGW---WWADPVAGLAIAAFAVREGLEAWRGDAC 207
>gi|238059826|ref|ZP_04604535.1| Co:Zn:Cd cation transporter [Micromonospora sp. ATCC 39149]
gi|237881637|gb|EEP70465.1| Co:Zn:Cd cation transporter [Micromonospora sp. ATCC 39149]
Length=230
Score = 97.1 bits (240), Expect = 2e-18, Method: Compositional matrix adjust.
Identities = 69/176 (40%), Positives = 96/176 (55%), Gaps = 5/176 (2%)
Query 46 EGAVGLWQGIAVGSVALTGWALGGGSEGLASAMVLWRFTGDRTWSATAEHRAQRGVAVSF 105
E V + G S AL G+ L E ++A V W+F G R A E A R +AVSF
Sbjct 13 EAVVAITAGTLASSTALIGFGLDSIIEVASAAAVAWQFAG-RDPEAR-EKTALRIIAVSF 70
Query 106 WLTAPYLVAESIRHLAGEHRAETSVIGIGLTAIALLLMPVLGWANHRVGERLGSGATAGE 165
+ A Y+ ES+R L G A+ S IG+ L ++LL+MPVL +A R G LGS + +
Sbjct 71 FALAAYVTVESVRALLGGAEAQHSSIGLVLAGLSLLIMPVLSYAQRRAGRELGSRSAVAD 130
Query 166 GTQNYLCAAQAAAVLLGLAITAVWSNGW-WIDPAIGLAIAGIAVWQGIRTWRGHGC 220
Q LC +A +L+GLA+ +++ GW W DP L IA +AV +G W+G C
Sbjct 131 SKQTLLCTYLSAVLLVGLAVNSLF--GWSWADPIAALVIAAVAVKEGREAWKGDSC 184
>gi|220914056|ref|YP_002489365.1| cation efflux protein [Arthrobacter chlorophenolicus A6]
gi|219860934|gb|ACL41276.1| cation efflux protein [Arthrobacter chlorophenolicus A6]
Length=257
Score = 96.7 bits (239), Expect = 2e-18, Method: Compositional matrix adjust.
Identities = 69/192 (36%), Positives = 97/192 (51%), Gaps = 5/192 (2%)
Query 30 RWARWLAWVSLAVLLTEGAVGLWQGIAVGSVALTGWALGGGSEGLASAMVL-WRFTGDRT 88
R R A ++ + E V LW G S AL G+ L E +ASA+ L W+F+
Sbjct 19 RRIRLFAAATITYNVIEAVVALWAGGVADSSALIGFGLDSVIE-VASAVALSWQFSAKDP 77
Query 89 WSATAEHRAQRGVAVSFWLTAPYLVAESIRHLAGEHRAETSVIGIGLTAIALLLMPVLGW 148
EH R +A+SF+ A ++ +++R LAG A+ S GI + A++L +MPVL W
Sbjct 78 ERR--EHLTLRIIAISFFALAAFVTVDAVRSLAGGGEAQHSTPGIVIAALSLAIMPVLSW 135
Query 149 ANHRVGERLGSGATAGEGTQNYLCAAQAAAVLLGLAITAVWSNGWWIDPAIGLAIAGIAV 208
A R G LGS + Q LC +A +L+GL + + W A L IAGIAV
Sbjct 136 AQRRAGRELGSRTAVADSKQTLLCTYLSAVLLVGLVLNSTLGWWWADA-AAALVIAGIAV 194
Query 209 WQGIRTWRGHGC 220
+G WRG C
Sbjct 195 REGFNAWRGDVC 206
>gi|183982149|ref|YP_001850440.1| metal transport protein [Mycobacterium marinum M]
gi|183175475|gb|ACC40585.1| conserved hypothetical metal transport protein [Mycobacterium
marinum M]
Length=237
Score = 95.5 bits (236), Expect = 5e-18, Method: Compositional matrix adjust.
Identities = 68/191 (36%), Positives = 100/191 (53%), Gaps = 3/191 (1%)
Query 30 RWARWLAWVSLAVLLTEGAVGLWQGIAVGSVALTGWALGGGSEGLASAMVLWRFTGDRTW 89
R R L ++ + VG+ G S AL G+ L E ++ V W+F G
Sbjct 49 RRVRMLVGATIGYKVIAAIVGVAAGEVASSTALIGFGLDSVIEVASALAVGWQFFGKHPE 108
Query 90 SATAEHRAQRGVAVSFWLTAPYLVAESIRHLAGEHRAETSVIGIGLTAIALLLMPVLGWA 149
+ E A +G+AVSF+ A Y+ ES+R L G AE S GI L A++LL+MP+L A
Sbjct 109 AR--ERLALKGIAVSFFALAAYITVESVRSLQGGDEAEHSTTGIVLAAVSLLVMPLLFHA 166
Query 150 NHRVGERLGSGATAGEGTQNYLCAAQAAAVLLGLAITAVWSNGWWIDPAIGLAIAGIAVW 209
RVG+ LGS + + Q+ LC + +L+GL + +++ W D + L IAG AV
Sbjct 167 KQRVGQELGSASVVADSRQSLLCIYLSGILLVGLLLNSLFGFSWA-DHVVALIIAGAAVK 225
Query 210 QGIRTWRGHGC 220
+G + WRG C
Sbjct 226 EGRQAWRGQHC 236
>gi|170782241|ref|YP_001710574.1| putative integral membrane protein [Clavibacter michiganensis
subsp. sepedonicus]
gi|169156810|emb|CAQ01974.1| putative integral membrane protein [Clavibacter michiganensis
subsp. sepedonicus]
Length=236
Score = 95.1 bits (235), Expect = 7e-18, Method: Compositional matrix adjust.
Identities = 64/164 (40%), Positives = 88/164 (54%), Gaps = 7/164 (4%)
Query 59 SVALTGWALGGGSEGLASAMVLWRFTGDRTWSATAEHRAQRGVAVSFWLTAPYLVAESIR 118
S AL + L E LA++ V W+F+ + E A R +AVSF A Y+ +++
Sbjct 54 STALVAFGLDSIVEVLAASAVAWQFSAPDPEAR--ERAALRLIAVSFLGLAAYVSVDAVL 111
Query 119 HLAGEHRAETSVIGIGLTAIALLLMPVLGWANHRVGERLGSGATAGEGTQNYLCAAQAAA 178
LAG + A S GI L A++L +MPVL R G LGS + + Q +CA +AA
Sbjct 112 ALAGGNEARPSPTGIVLAALSLAVMPVLSLLERRTGTELGSASAVADSRQTLVCAWLSAA 171
Query 179 VLLGLAITA--VWSNGWWIDPAIGLAIAGIAVWQGIRTWRGHGC 220
+L+GL + A W WW DP GLAIA AV +G+ WRG C
Sbjct 172 LLIGLLLDAGLGW---WWADPVAGLAIAAFAVREGVEAWRGDAC 212
>gi|271966330|ref|YP_003340526.1| Co/Zn/Cd cation transporter-like protein [Streptosporangium roseum
DSM 43021]
gi|270509505|gb|ACZ87783.1| Co/Zn/Cd cation transporter-like protein [Streptosporangium roseum
DSM 43021]
Length=243
Score = 95.1 bits (235), Expect = 7e-18, Method: Compositional matrix adjust.
Identities = 78/207 (38%), Positives = 108/207 (53%), Gaps = 14/207 (6%)
Query 18 SVAREAEWQRNVRWARWLAWVSLAVLLTEGAVGLWQGIAVGSVALTGWALGGGSEGLASA 77
S AR A R VR L ++ L E V + G S AL G+ L E ++A
Sbjct 9 SPARRATLIRRVRL---LVAATITYNLIEAVVAITAGTLASSAALVGFGLDSVVEVASAA 65
Query 78 MVLWRFTGDRTWSATAEHR---AQRGVAVSFWLTAPYLVAESIRHLAGEHRAETSVIGIG 134
V W+F+ +A E R A R +AVSF+ A Y+ +++R L G AE S G+
Sbjct 66 AVAWQFS-----AADHERREKSALRVIAVSFFALAAYVTLDAVRALLGAGEAEHSTAGLA 120
Query 135 LTAIALLLMPVLGWANHRVGERLGSGATAGEGTQNYLCAAQAAAVLLGLAITAVWSNGW- 193
L A++LL+MP L A R G LGS + + Q LC +A +L+GLA+ +++ GW
Sbjct 121 LAALSLLVMPFLSAAQRRAGRELGSASAVADSKQTLLCTYLSAVLLVGLALNSLF--GWS 178
Query 194 WIDPAIGLAIAGIAVWQGIRTWRGHGC 220
W DP L IAG+AV +G WRG GC
Sbjct 179 WADPIAALVIAGVAVKEGRAAWRGDGC 205
>gi|291302839|ref|YP_003514117.1| cation efflux protein [Stackebrandtia nassauensis DSM 44728]
gi|290572059|gb|ADD45024.1| cation efflux protein [Stackebrandtia nassauensis DSM 44728]
Length=240
Score = 94.7 bits (234), Expect = 8e-18, Method: Compositional matrix adjust.
Identities = 67/205 (33%), Positives = 104/205 (51%), Gaps = 6/205 (2%)
Query 17 VSVAREAEWQRNVRWARWLAWVSLAVLLTEGAVGLWQGIAVGSVALTGWALGGGSEGLAS 76
VS+ E + N R LA+ + L EG V + G S AL G+ L E ++
Sbjct 4 VSLTAERRAKLNKRCLH-LAYATAGYNLAEGIVAVTAGAIASSTALLGFGLDSFVEVSSA 62
Query 77 AMVLWRFTGDRTWSATAEHRAQRGVAVSFWLTAPYLVAESIRHLAGEHRAETSVIGIGLT 136
+V+W+F E A + +A SF+ A ++ +++R L G+ AE S +GI +
Sbjct 63 LVVIWQFRSK--LPEAREKLALKLIAASFFALAAWITIDAVRSLLGQGEAEPSPVGIAIA 120
Query 137 AIALLLMPVLGWANHRVGERLGSGATAGEGTQNYLCAAQAAAVLLGLAITAVWSNGW-WI 195
A+++++MP L WA R G+ LGS + Q LC + +L+GL + A GW W
Sbjct 121 AVSVIVMPALVWAKRRTGKELGSATVVADSVQTLLCTYLSGILLIGLVLNATL--GWSWA 178
Query 196 DPAIGLAIAGIAVWQGIRTWRGHGC 220
DP L IA +A+ +G+ WRG C
Sbjct 179 DPIAALVIAAVAIKEGVEAWRGEQC 203
>gi|284993397|ref|YP_003411952.1| cation efflux protein [Geodermatophilus obscurus DSM 43160]
gi|284066643|gb|ADB77581.1| cation efflux protein [Geodermatophilus obscurus DSM 43160]
Length=256
Score = 94.7 bits (234), Expect = 8e-18, Method: Compositional matrix adjust.
Identities = 64/160 (40%), Positives = 86/160 (54%), Gaps = 5/160 (3%)
Query 62 LTGWALGGGSEGLASAMVLWRFTGDRTWSATAEHRAQRGVAVSFWLTAPYLVAESIRHLA 121
L G+ L E + +VLW+F + E +A R +A+SF A Y+ AES+R L
Sbjct 52 LVGFGLDSVVEVSSGLIVLWQFR--HRLPESRERQALRLMAISFLALAAYVAAESVRVLL 109
Query 122 GEHRAETSVIGIGLTAIALLLMPVLGWANHRVGERLGSGATAGEGTQNYLCAAQAAAVLL 181
E S +GIGL +L++MP L WA R G LGS A + TQ LC + +L+
Sbjct 110 SGGEPEASPVGIGLAIASLVVMPFLSWAQRRTGRALGSHAVVADSTQTLLCTYLSVVLLV 169
Query 182 GLAITAVWSNGW-WIDPAIGLAIAGIAVWQGIRTWRGHGC 220
GL + A GW W DP GL IA +AV +G+ WRG GC
Sbjct 170 GLVLNATL--GWSWADPVAGLVIAVVAVREGVEAWRGEGC 207
>gi|84496059|ref|ZP_00994913.1| putative integral membrane protein [Janibacter sp. HTCC2649]
gi|84382827|gb|EAP98708.1| putative integral membrane protein [Janibacter sp. HTCC2649]
Length=243
Score = 94.7 bits (234), Expect = 9e-18, Method: Compositional matrix adjust.
Identities = 71/193 (37%), Positives = 100/193 (52%), Gaps = 5/193 (2%)
Query 29 VRWARWLAWVSLAVLLTEGAVGLWQGIAVGSVALTGWALGGGSEGLASAMVLWRFTGDRT 88
+R A+ LA S+A E + + G GS AL G+ L E + ++LW+F
Sbjct 1 MRRAQLLAGASVAYNTVEAVIAITAGNIAGSSALVGFGLDSLVEVSSGLVILWQFR--HP 58
Query 89 WSATAEHRAQRGVAVSFWLTAPYLVAESIRHLAGEHRAETSVIGIGLTAIALLLMPVLGW 148
+ E +QR +A+SF+ A YL E+ L + ++S IGIGL +L +MP L
Sbjct 59 MPESRERTSQRLIAISFFALAAYLTVEAGHALLTGAQPDSSPIGIGLAIASLAVMPFLSV 118
Query 149 ANHRVGERLGSGATAGEGTQNYLCAAQAAAVLLGLAITAVWSNGW-WIDPAIGLAIAGIA 207
R G LGSGA G+GTQ LC +A +L+GL + A S GW W DP L IA +A
Sbjct 119 WQRRTGRELGSGAVEGDGTQTLLCTYLSAVLLIGLVLNA--SLGWTWADPVAALIIAAVA 176
Query 208 VWQGIRTWRGHGC 220
+G W+G C
Sbjct 177 AREGWENWQGDDC 189
Lambda K H
0.320 0.133 0.443
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 279760868288
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
Posted date: Sep 5, 2011 4:36 AM
Number of letters in database: 5,219,829,388
Number of sequences in database: 15,229,318
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40