BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv3295 Length=221 Score E Sequences producing significant alignments: (Bits) Value gi|15610431|ref|NP_217812.1| TetR family transcriptional regulat... 449 1e-124 gi|240171593|ref|ZP_04750252.1| putative transcriptional regulat... 407 8e-112 gi|118618116|ref|YP_906448.1| TetR family transcriptional regula... 389 2e-106 gi|15827303|ref|NP_301566.1| TetR family transcriptional regulat... 386 1e-105 gi|466852|gb|AAA85928.1| B1308_C2_181 [Mycobacterium leprae] 386 2e-105 gi|342861509|ref|ZP_08718156.1| hypothetical protein MCOL_21591 ... 370 6e-101 gi|118463548|ref|YP_883407.1| hypothetical protein MAV_4266 [Myc... 369 2e-100 gi|41409512|ref|NP_962348.1| hypothetical protein MAP3414 [Mycob... 366 1e-99 gi|254819534|ref|ZP_05224535.1| hypothetical protein MintA_06394... 364 5e-99 gi|296168908|ref|ZP_06850577.1| TetR family transcriptional regu... 362 3e-98 gi|289759438|ref|ZP_06518816.1| transcriptional regulator [Mycob... 335 4e-90 gi|145225380|ref|YP_001136058.1| TetR family transcriptional reg... 290 9e-77 gi|315445728|ref|YP_004078607.1| TetR family transcriptional reg... 290 1e-76 gi|120402646|ref|YP_952475.1| TetR family transcriptional regula... 288 4e-76 gi|169630729|ref|YP_001704378.1| TetR family transcriptional reg... 192 3e-47 gi|21219322|ref|NP_625101.1| TetR family transcriptional regulat... 132 3e-29 gi|289773529|ref|ZP_06532907.1| TetR family transcriptional regu... 132 4e-29 gi|29833969|ref|NP_828603.1| TetR family transcriptional regulat... 128 5e-28 gi|302562300|ref|ZP_07314642.1| TetR-family transcriptional regu... 127 1e-27 gi|291435483|ref|ZP_06574873.1| TetR-family transcriptional regu... 127 2e-27 gi|117165014|emb|CAJ88566.1| putative TetR-family transcriptiona... 124 7e-27 gi|290955499|ref|YP_003486681.1| TetR family transcriptional reg... 122 4e-26 gi|302555964|ref|ZP_07308306.1| TetR family transcriptional regu... 120 1e-25 gi|302529370|ref|ZP_07281712.1| TetR family transcriptional regu... 117 8e-25 gi|297204231|ref|ZP_06921628.1| TetR-family transcriptional regu... 117 1e-24 gi|226364135|ref|YP_002781917.1| TetR family transcriptional reg... 114 7e-24 gi|111021600|ref|YP_704572.1| TetR family transcriptional regula... 112 3e-23 gi|329936443|ref|ZP_08286208.1| TetR family transcriptional regu... 109 3e-22 gi|229494211|ref|ZP_04387974.1| TetR-family transcriptional regu... 108 5e-22 gi|226304386|ref|YP_002764344.1| TetR family transcriptional reg... 108 5e-22 gi|302538928|ref|ZP_07291270.1| predicted protein [Streptomyces ... 105 6e-21 gi|297153955|gb|ADI03667.1| transcriptional regulator, TetR fami... 103 2e-20 gi|302556344|ref|ZP_07308686.1| TetR-family transcriptional regu... 103 2e-20 gi|302528636|ref|ZP_07280978.1| predicted protein [Streptomyces ... 99.0 4e-19 gi|328884825|emb|CCA58064.1| Transcriptional regulator, TetR fam... 99.0 5e-19 gi|343928038|ref|ZP_08767503.1| putative TetR family transcripti... 93.6 2e-17 gi|256391154|ref|YP_003112718.1| TetR family transcriptional reg... 90.1 2e-16 gi|229493748|ref|ZP_04387530.1| regulatory protein, TetR [Rhodoc... 89.4 4e-16 gi|226307610|ref|YP_002767570.1| TetR family transcriptional reg... 89.4 4e-16 gi|326333156|ref|ZP_08199404.1| putative transcriptional regulat... 89.0 5e-16 gi|134100745|ref|YP_001106406.1| transcriptional regulator [Sacc... 88.2 9e-16 gi|333921585|ref|YP_004495166.1| TetR family transcriptional reg... 87.8 1e-15 gi|54026673|ref|YP_120915.1| putative transcriptional regulator ... 87.4 1e-15 gi|111022972|ref|YP_705944.1| TetR family transcriptional regula... 86.3 3e-15 gi|226365478|ref|YP_002783261.1| TetR family transcriptional reg... 85.1 6e-15 gi|312138898|ref|YP_004006234.1| tetr family transcriptional reg... 85.1 7e-15 gi|325676395|ref|ZP_08156073.1| TetR family transcriptional regu... 85.1 7e-15 gi|262201822|ref|YP_003273030.1| TetR family transcriptional reg... 84.0 1e-14 gi|326382055|ref|ZP_08203748.1| regulatory protein TetR [Gordoni... 83.6 2e-14 gi|326771651|ref|ZP_08230936.1| TetR family transcriptional regu... 81.6 7e-14 >gi|15610431|ref|NP_217812.1| TetR family transcriptional regulator [Mycobacterium tuberculosis H37Rv] gi|15842886|ref|NP_337923.1| TetR family transcriptional regulator [Mycobacterium tuberculosis CDC1551] gi|31794475|ref|NP_856968.1| TetR family transcriptional regulator [Mycobacterium bovis AF2122/97] 80 more sequence titles Length=221 Score = 449 bits (1155), Expect = 1e-124, Method: Compositional matrix adjust. Identities = 221/221 (100%), Positives = 221/221 (100%), Gaps = 0/221 (0%) Query 1 MATARRRLSPQDRRAELLALGAEVFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFF 60 MATARRRLSPQDRRAELLALGAEVFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFF Sbjct 1 MATARRRLSPQDRRAELLALGAEVFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFF 60 Query 61 AAVVKDEADRLYAATNKAPAPGMTMFEEIRTGVLAYMAYHQQNPEAAWAAYVGLGRSDPV 120 AAVVKDEADRLYAATNKAPAPGMTMFEEIRTGVLAYMAYHQQNPEAAWAAYVGLGRSDPV Sbjct 61 AAVVKDEADRLYAATNKAPAPGMTMFEEIRTGVLAYMAYHQQNPEAAWAAYVGLGRSDPV 120 Query 121 LLGIDDEAKNRQMEHIMSRIAEVVSGIDRDNTLDPEVERDLRVIIHGWLAFTFELCRQRI 180 LLGIDDEAKNRQMEHIMSRIAEVVSGIDRDNTLDPEVERDLRVIIHGWLAFTFELCRQRI Sbjct 121 LLGIDDEAKNRQMEHIMSRIAEVVSGIDRDNTLDPEVERDLRVIIHGWLAFTFELCRQRI 180 Query 181 MDPSTDAERLADACAHALLDAISRLPQIPAELADAMATARM 221 MDPSTDAERLADACAHALLDAISRLPQIPAELADAMATARM Sbjct 181 MDPSTDAERLADACAHALLDAISRLPQIPAELADAMATARM 221 >gi|240171593|ref|ZP_04750252.1| putative transcriptional regulatory protein [Mycobacterium kansasii ATCC 12478] Length=225 Score = 407 bits (1045), Expect = 8e-112, Method: Compositional matrix adjust. Identities = 197/220 (90%), Positives = 210/220 (96%), Gaps = 0/220 (0%) Query 1 MATARRRLSPQDRRAELLALGAEVFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFF 60 MATARRRLSP+DRRAELLALGAEVFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFF Sbjct 1 MATARRRLSPEDRRAELLALGAEVFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFF 60 Query 61 AAVVKDEADRLYAATNKAPAPGMTMFEEIRTGVLAYMAYHQQNPEAAWAAYVGLGRSDPV 120 AAVVKDEADRLYAATNK PAPG+TMFEEIRTGVLAYMAYHQQNPEAAWAAYVGLGRSDPV Sbjct 61 AAVVKDEADRLYAATNKPPAPGLTMFEEIRTGVLAYMAYHQQNPEAAWAAYVGLGRSDPV 120 Query 121 LLGIDDEAKNRQMEHIMSRIAEVVSGIDRDNTLDPEVERDLRVIIHGWLAFTFELCRQRI 180 LLGIDDEAKNRQMEH+M+RI EVVSGI + L+PEVERDLRVII GW+AFTFE+CRQRI Sbjct 121 LLGIDDEAKNRQMEHVMTRIGEVVSGIPGSSALEPEVERDLRVIIFGWIAFTFEICRQRI 180 Query 181 MDPSTDAERLADACAHALLDAISRLPQIPAELADAMATAR 220 MDP+TDA+RLADACAH LLDAI+R+PQIP +LA AMATAR Sbjct 181 MDPTTDADRLADACAHNLLDAIARVPQIPEQLAHAMATAR 220 >gi|118618116|ref|YP_906448.1| TetR family transcriptional regulator [Mycobacterium ulcerans Agy99] gi|183981261|ref|YP_001849552.1| TetR family transcriptional regulator [Mycobacterium marinum M] gi|118570226|gb|ABL04977.1| transcriptional regulatory protein (probably TetR-family) [Mycobacterium ulcerans Agy99] gi|183174587|gb|ACC39697.1| transcriptional regulatory protein (probably TetR-family) [Mycobacterium marinum M] Length=224 Score = 389 bits (998), Expect = 2e-106, Method: Compositional matrix adjust. Identities = 190/220 (87%), Positives = 202/220 (92%), Gaps = 0/220 (0%) Query 1 MATARRRLSPQDRRAELLALGAEVFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFF 60 MATARRRLSP+DRRAELLALGAEVFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFF Sbjct 1 MATARRRLSPEDRRAELLALGAEVFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFF 60 Query 61 AAVVKDEADRLYAATNKAPAPGMTMFEEIRTGVLAYMAYHQQNPEAAWAAYVGLGRSDPV 120 AAVVKDEADRLY AT+ GMTMFEEIR GVLAYMAYHQQNPEAAWAAYVGLGRSDPV Sbjct 61 AAVVKDEADRLYEATSIESPVGMTMFEEIRLGVLAYMAYHQQNPEAAWAAYVGLGRSDPV 120 Query 121 LLGIDDEAKNRQMEHIMSRIAEVVSGIDRDNTLDPEVERDLRVIIHGWLAFTFELCRQRI 180 LLGIDDEAKNRQMEHIM+RI +VVSGI LD VERDLRVII+GWLAFTFE+CRQRI Sbjct 121 LLGIDDEAKNRQMEHIMTRIGQVVSGIPGSTALDQHVERDLRVIIYGWLAFTFEICRQRI 180 Query 181 MDPSTDAERLADACAHALLDAISRLPQIPAELADAMATAR 220 MDP TDA+RLADACAH LLD+I+R+P+IP ELA+AMATAR Sbjct 181 MDPGTDADRLADACAHTLLDSIARVPEIPGELAEAMATAR 220 >gi|15827303|ref|NP_301566.1| TetR family transcriptional regulator [Mycobacterium leprae TN] gi|221229781|ref|YP_002503197.1| putative TetR-family transcriptional regulator [Mycobacterium leprae Br4923] gi|13092852|emb|CAC30226.1| putative TetR-family transcriptional regulator [Mycobacterium leprae] gi|219932888|emb|CAR70811.1| putative TetR-family transcriptional regulator [Mycobacterium leprae Br4923] Length=223 Score = 386 bits (992), Expect = 1e-105, Method: Compositional matrix adjust. Identities = 188/220 (86%), Positives = 205/220 (94%), Gaps = 1/220 (0%) Query 1 MATARRRLSPQDRRAELLALGAEVFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFF 60 M TARRRLSP+DRRAELLALGAEVFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFF Sbjct 1 MTTARRRLSPEDRRAELLALGAEVFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFF 60 Query 61 AAVVKDEADRLYAATNKAPAPGMTMFEEIRTGVLAYMAYHQQNPEAAWAAYVGLGRSDPV 120 AAVVKDEADRLYAATN P G+TMFEE+R GVLAYMAYH+QNPEAAWAAYVGLGRSDPV Sbjct 61 AAVVKDEADRLYAATNIPPPAGLTMFEEVRVGVLAYMAYHKQNPEAAWAAYVGLGRSDPV 120 Query 121 LLGIDDEAKNRQMEHIMSRIAEVVSGIDRDNTLDPEVERDLRVIIHGWLAFTFELCRQRI 180 LLGIDDEAKNRQMEHIMSRI +VVS + ++ L P++ERDLRVI+HGWLAFTFE+CRQRI Sbjct 121 LLGIDDEAKNRQMEHIMSRIGDVVSVVP-ESKLHPDIERDLRVIVHGWLAFTFEVCRQRI 179 Query 181 MDPSTDAERLADACAHALLDAISRLPQIPAELADAMATAR 220 MDPSTDA+RLAD+CAHALLDAI+R+P+I ELADAMA AR Sbjct 180 MDPSTDADRLADSCAHALLDAIARVPEISKELADAMAIAR 219 >gi|466852|gb|AAA85928.1| B1308_C2_181 [Mycobacterium leprae] Length=242 Score = 386 bits (991), Expect = 2e-105, Method: Compositional matrix adjust. Identities = 188/220 (86%), Positives = 205/220 (94%), Gaps = 1/220 (0%) Query 1 MATARRRLSPQDRRAELLALGAEVFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFF 60 M TARRRLSP+DRRAELLALGAEVFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFF Sbjct 20 MTTARRRLSPEDRRAELLALGAEVFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFF 79 Query 61 AAVVKDEADRLYAATNKAPAPGMTMFEEIRTGVLAYMAYHQQNPEAAWAAYVGLGRSDPV 120 AAVVKDEADRLYAATN P G+TMFEE+R GVLAYMAYH+QNPEAAWAAYVGLGRSDPV Sbjct 80 AAVVKDEADRLYAATNIPPPAGLTMFEEVRVGVLAYMAYHKQNPEAAWAAYVGLGRSDPV 139 Query 121 LLGIDDEAKNRQMEHIMSRIAEVVSGIDRDNTLDPEVERDLRVIIHGWLAFTFELCRQRI 180 LLGIDDEAKNRQMEHIMSRI +VVS + ++ L P++ERDLRVI+HGWLAFTFE+CRQRI Sbjct 140 LLGIDDEAKNRQMEHIMSRIGDVVSVVP-ESKLHPDIERDLRVIVHGWLAFTFEVCRQRI 198 Query 181 MDPSTDAERLADACAHALLDAISRLPQIPAELADAMATAR 220 MDPSTDA+RLAD+CAHALLDAI+R+P+I ELADAMA AR Sbjct 199 MDPSTDADRLADSCAHALLDAIARVPEISKELADAMAIAR 238 >gi|342861509|ref|ZP_08718156.1| hypothetical protein MCOL_21591 [Mycobacterium colombiense CECT 3035] gi|342130998|gb|EGT84287.1| hypothetical protein MCOL_21591 [Mycobacterium colombiense CECT 3035] Length=223 Score = 370 bits (951), Expect = 6e-101, Method: Compositional matrix adjust. Identities = 178/221 (81%), Positives = 203/221 (92%), Gaps = 1/221 (0%) Query 1 MATARRRLSPQDRRAELLALGAEVFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFF 60 M TARRRLSP+DRRAELLALGAEVFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFF Sbjct 1 MPTARRRLSPEDRRAELLALGAEVFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFF 60 Query 61 AAVVKDEADRLYAATNKAPAPGMTMFEEIRTGVLAYMAYHQQNPEAAWAAYVGLGRSDPV 120 AAVVKDEADRLY TN A G+TM+EE+RTGV+AYMAYH+QNPEAAWAAYVGLGRSDPV Sbjct 61 AAVVKDEADRLYENTNMDDATGLTMYEEVRTGVMAYMAYHEQNPEAAWAAYVGLGRSDPV 120 Query 121 LLGIDDEAKNRQMEHIMSRIAEVVSGIDRDNTLDPEVERDLRVIIHGWLAFTFELCRQRI 180 LLG+DDEAKNRQ+EHIMSRI+++V+ L+P+VERDLRVI HGWLAFTFELCRQRI Sbjct 121 LLGVDDEAKNRQLEHIMSRISDLVAKTPA-RKLEPDVERDLRVICHGWLAFTFELCRQRI 179 Query 181 MDPSTDAERLADACAHALLDAISRLPQIPAELADAMATARM 221 +DP+T+A+RLADACAH+L DAI+R+P+IP EL+ AM+TAR+ Sbjct 180 IDPTTNADRLADACAHSLFDAIARVPEIPEELSHAMSTARI 220 >gi|118463548|ref|YP_883407.1| hypothetical protein MAV_4266 [Mycobacterium avium 104] gi|254776701|ref|ZP_05218217.1| hypothetical protein MaviaA2_18821 [Mycobacterium avium subsp. avium ATCC 25291] gi|118164835|gb|ABK65732.1| conserved hypothetical protein [Mycobacterium avium 104] Length=219 Score = 369 bits (946), Expect = 2e-100, Method: Compositional matrix adjust. Identities = 177/221 (81%), Positives = 202/221 (92%), Gaps = 2/221 (0%) Query 1 MATARRRLSPQDRRAELLALGAEVFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFF 60 MATARRRLSP+DRRAELLALGAEVFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFF Sbjct 1 MATARRRLSPEDRRAELLALGAEVFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFF 60 Query 61 AAVVKDEADRLYAATNKAPAPGMTMFEEIRTGVLAYMAYHQQNPEAAWAAYVGLGRSDPV 120 AAVVKDEADRLY TN G+TM+EEIR GVLAYMAYH+QNPEAAWAAYVGLGRSDPV Sbjct 61 AAVVKDEADRLYENTNMDDVTGLTMYEEIRVGVLAYMAYHEQNPEAAWAAYVGLGRSDPV 120 Query 121 LLGIDDEAKNRQMEHIMSRIAEVVSGIDRDNTLDPEVERDLRVIIHGWLAFTFELCRQRI 180 LLG++D+AKNRQMEHIMSRI ++++ + TL+P+VER LRVI+HGWLAFTFE+CRQRI Sbjct 121 LLGVEDDAKNRQMEHIMSRINQLLAEV--PATLEPDVERHLRVILHGWLAFTFEICRQRI 178 Query 181 MDPSTDAERLADACAHALLDAISRLPQIPAELADAMATARM 221 +DP+TDA++LADACAHALLDAI R+P+IP EL +AMA +R+ Sbjct 179 IDPTTDADKLADACAHALLDAIGRVPEIPEELGEAMANSRL 219 >gi|41409512|ref|NP_962348.1| hypothetical protein MAP3414 [Mycobacterium avium subsp. paratuberculosis K-10] gi|41398343|gb|AAS05964.1| hypothetical protein MAP_3414 [Mycobacterium avium subsp. paratuberculosis K-10] gi|336459622|gb|EGO38557.1| transcriptional regulator [Mycobacterium avium subsp. paratuberculosis S397] Length=219 Score = 366 bits (940), Expect = 1e-99, Method: Compositional matrix adjust. Identities = 176/221 (80%), Positives = 201/221 (91%), Gaps = 2/221 (0%) Query 1 MATARRRLSPQDRRAELLALGAEVFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFF 60 MATARRRLSP+DRRAELLALGAEVFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFF Sbjct 1 MATARRRLSPEDRRAELLALGAEVFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFF 60 Query 61 AAVVKDEADRLYAATNKAPAPGMTMFEEIRTGVLAYMAYHQQNPEAAWAAYVGLGRSDPV 120 AAVVKDEADRLY TN G+TM+EEIR GVLAYMAYH+QNPEAAWAAYVGLGRSDPV Sbjct 61 AAVVKDEADRLYENTNMDDVTGLTMYEEIRVGVLAYMAYHEQNPEAAWAAYVGLGRSDPV 120 Query 121 LLGIDDEAKNRQMEHIMSRIAEVVSGIDRDNTLDPEVERDLRVIIHGWLAFTFELCRQRI 180 LLG++D+AKNRQMEHIMSRI ++++ + T +P+VER LRVI+HGWLAFTFE+CRQRI Sbjct 121 LLGVEDDAKNRQMEHIMSRINQLLAEV--PATREPDVERHLRVILHGWLAFTFEICRQRI 178 Query 181 MDPSTDAERLADACAHALLDAISRLPQIPAELADAMATARM 221 +DP+TDA++LADACAHALLDAI R+P+IP EL +AMA +R+ Sbjct 179 IDPTTDADKLADACAHALLDAIGRVPEIPEELGEAMANSRL 219 >gi|254819534|ref|ZP_05224535.1| hypothetical protein MintA_06394 [Mycobacterium intracellulare ATCC 13950] Length=219 Score = 364 bits (935), Expect = 5e-99, Method: Compositional matrix adjust. Identities = 172/221 (78%), Positives = 202/221 (92%), Gaps = 2/221 (0%) Query 1 MATARRRLSPQDRRAELLALGAEVFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFF 60 M TARRRLSP+DRRAELLALGAEVFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFF Sbjct 1 MPTARRRLSPEDRRAELLALGAEVFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFF 60 Query 61 AAVVKDEADRLYAATNKAPAPGMTMFEEIRTGVLAYMAYHQQNPEAAWAAYVGLGRSDPV 120 AAVVKDEADRLY TN G+TM+EEIR GVLAYMAYH+QNPEAAWAAYVGLGRSDPV Sbjct 61 AAVVKDEADRLYENTNMDDVTGLTMYEEIRVGVLAYMAYHEQNPEAAWAAYVGLGRSDPV 120 Query 121 LLGIDDEAKNRQMEHIMSRIAEVVSGIDRDNTLDPEVERDLRVIIHGWLAFTFELCRQRI 180 LLG++D+AKNRQMEHIMSRI ++++ + + ++P+VER LRVI+HGWLA TFE+CRQRI Sbjct 121 LLGVEDDAKNRQMEHIMSRINQLLTEL--NTGMEPDVERHLRVILHGWLALTFEICRQRI 178 Query 181 MDPSTDAERLADACAHALLDAISRLPQIPAELADAMATARM 221 +DP+TDA++LADACAHALLDAI+R+P+IP +L +AM+T+R+ Sbjct 179 IDPTTDADKLADACAHALLDAIARVPEIPEKLGEAMSTSRL 219 >gi|296168908|ref|ZP_06850577.1| TetR family transcriptional regulator [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295896377|gb|EFG76030.1| TetR family transcriptional regulator [Mycobacterium parascrofulaceum ATCC BAA-614] Length=229 Score = 362 bits (928), Expect = 3e-98, Method: Compositional matrix adjust. Identities = 175/221 (80%), Positives = 197/221 (90%), Gaps = 1/221 (0%) Query 1 MATARRRLSPQDRRAELLALGAEVFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFF 60 M T RRRLSP+DRRAELLALGAEVFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFF Sbjct 7 MPTGRRRLSPEDRRAELLALGAEVFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFF 66 Query 61 AAVVKDEADRLYAATNKAPAPGMTMFEEIRTGVLAYMAYHQQNPEAAWAAYVGLGRSDPV 120 AAVVKDEADRLY TN A G+TM+EE+R GV+AYMAYH+QNPEAAWAAYVGLGRSDPV Sbjct 67 AAVVKDEADRLYETTNMDDATGLTMYEEVRMGVMAYMAYHEQNPEAAWAAYVGLGRSDPV 126 Query 121 LLGIDDEAKNRQMEHIMSRIAEVVSGIDRDNTLDPEVERDLRVIIHGWLAFTFELCRQRI 180 LLG+DDEAKNRQ+EHIM RI ++V+ I L+ +VERDLRVI HGWLAFTFELCRQRI Sbjct 127 LLGVDDEAKNRQLEHIMGRIHDLVADIS-GAKLEADVERDLRVICHGWLAFTFELCRQRI 185 Query 181 MDPSTDAERLADACAHALLDAISRLPQIPAELADAMATARM 221 +DP+ +A+RLADACAH+L DAI+R+PQIP EL+ AMATA + Sbjct 186 IDPTINADRLADACAHSLFDAIARVPQIPEELSHAMATASI 226 >gi|289759438|ref|ZP_06518816.1| transcriptional regulator [Mycobacterium tuberculosis T85] gi|289715002|gb|EFD79014.1| transcriptional regulator [Mycobacterium tuberculosis T85] Length=164 Score = 335 bits (858), Expect = 4e-90, Method: Compositional matrix adjust. Identities = 163/163 (100%), Positives = 163/163 (100%), Gaps = 0/163 (0%) Query 59 FFAAVVKDEADRLYAATNKAPAPGMTMFEEIRTGVLAYMAYHQQNPEAAWAAYVGLGRSD 118 FFAAVVKDEADRLYAATNKAPAPGMTMFEEIRTGVLAYMAYHQQNPEAAWAAYVGLGRSD Sbjct 2 FFAAVVKDEADRLYAATNKAPAPGMTMFEEIRTGVLAYMAYHQQNPEAAWAAYVGLGRSD 61 Query 119 PVLLGIDDEAKNRQMEHIMSRIAEVVSGIDRDNTLDPEVERDLRVIIHGWLAFTFELCRQ 178 PVLLGIDDEAKNRQMEHIMSRIAEVVSGIDRDNTLDPEVERDLRVIIHGWLAFTFELCRQ Sbjct 62 PVLLGIDDEAKNRQMEHIMSRIAEVVSGIDRDNTLDPEVERDLRVIIHGWLAFTFELCRQ 121 Query 179 RIMDPSTDAERLADACAHALLDAISRLPQIPAELADAMATARM 221 RIMDPSTDAERLADACAHALLDAISRLPQIPAELADAMATARM Sbjct 122 RIMDPSTDAERLADACAHALLDAISRLPQIPAELADAMATARM 164 >gi|145225380|ref|YP_001136058.1| TetR family transcriptional regulator [Mycobacterium gilvum PYR-GCK] gi|145217866|gb|ABP47270.1| transcriptional regulator, TetR family [Mycobacterium gilvum PYR-GCK] Length=215 Score = 290 bits (743), Expect = 9e-77, Method: Compositional matrix adjust. Identities = 144/220 (66%), Positives = 175/220 (80%), Gaps = 6/220 (2%) Query 1 MATARRRLSPQDRRAELLALGAEVFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFF 60 MA ARRRLSP DRR ELLALGAEVFG+RPYDEVRIDEIAERAGVSRALMYHYFPDKRAFF Sbjct 1 MAEARRRLSPDDRRNELLALGAEVFGQRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFF 60 Query 61 AAVVKDEADRLYAATNKAPAPGMTMFEEIRTGVLAYMAYHQQNPEAAWAAYVGLGRSDPV 120 AAVV+ E++RL+ ATN PG T+F ++R GVLAY+ Y + +P AWAAY+G+ RSDPV Sbjct 61 AAVVRAESERLFDATNTPAQPGQTLFTQVRAGVLAYLRYDELHPHGAWAAYMGMSRSDPV 120 Query 121 LLGIDDEAKNRQMEHIMSRIAEVVSGIDRDNTLDPEVERDLRVIIHGWLAFTFELCRQRI 180 L GIDD +RQ I+ R V +G++ LD +VERDLR ++GWLAFTFE+CRQR+ Sbjct 121 LRGIDDHDNDRQANRIIDR---VTAGVE---PLDAKVERDLRAAVYGWLAFTFEMCRQRL 174 Query 181 MDPSTDAERLADACAHALLDAISRLPQIPAELADAMATAR 220 MD S DA+ L D CAHAL+DA++R+P IPA+LA+A+A R Sbjct 175 MDASLDADYLGDLCAHALMDALARVPGIPADLAEAVAPDR 214 >gi|315445728|ref|YP_004078607.1| TetR family transcriptional regulator [Mycobacterium sp. Spyr1] gi|315264031|gb|ADU00773.1| transcriptional regulator, TetR family [Mycobacterium sp. Spyr1] Length=215 Score = 290 bits (741), Expect = 1e-76, Method: Compositional matrix adjust. Identities = 143/220 (65%), Positives = 175/220 (80%), Gaps = 6/220 (2%) Query 1 MATARRRLSPQDRRAELLALGAEVFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFF 60 MA ARRRLSP DRR ELLALGAEVFG+RPYDEVRIDEIAERAGVSRALMYHYFPDKRAFF Sbjct 1 MAEARRRLSPDDRRNELLALGAEVFGQRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFF 60 Query 61 AAVVKDEADRLYAATNKAPAPGMTMFEEIRTGVLAYMAYHQQNPEAAWAAYVGLGRSDPV 120 AAVV+ E++RL+ ATN PG T+F ++R GVLAY+ Y + +P AWAAY+G+ RSDPV Sbjct 61 AAVVRAESERLFDATNTPAQPGQTLFTQVRAGVLAYLRYDELHPHGAWAAYMGMSRSDPV 120 Query 121 LLGIDDEAKNRQMEHIMSRIAEVVSGIDRDNTLDPEVERDLRVIIHGWLAFTFELCRQRI 180 L GIDD +RQ I+ R V +G++ LD +VERDLR ++GWLAFTFE+CRQR+ Sbjct 121 LRGIDDHDNDRQANRIIDR---VTAGVE---PLDSKVERDLRAAVYGWLAFTFEMCRQRL 174 Query 181 MDPSTDAERLADACAHALLDAISRLPQIPAELADAMATAR 220 MD S DA+ + D CAHAL+DA++R+P IPA+LA+A+A R Sbjct 175 MDASLDADYIGDLCAHALMDALARVPGIPADLAEAVAPDR 214 >gi|120402646|ref|YP_952475.1| TetR family transcriptional regulator [Mycobacterium vanbaalenii PYR-1] gi|119955464|gb|ABM12469.1| transcriptional regulator, TetR family [Mycobacterium vanbaalenii PYR-1] Length=216 Score = 288 bits (737), Expect = 4e-76, Method: Compositional matrix adjust. Identities = 138/220 (63%), Positives = 170/220 (78%), Gaps = 5/220 (2%) Query 1 MATARRRLSPQDRRAELLALGAEVFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFF 60 MA RRRLSP +RR+ELL LGAEVFG+RPYDEVRIDEIAERAGVSRALMYHYFPDKRAFF Sbjct 1 MAGPRRRLSPDERRSELLTLGAEVFGQRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFF 60 Query 61 AAVVKDEADRLYAATNKAPAPGMTMFEEIRTGVLAYMAYHQQNPEAAWAAYVGLGRSDPV 120 AAVV+ E +RL+ ATN P PG T+F ++R GVLAY+ Y + +P AWAAY+G+GRSDP+ Sbjct 61 AAVVRAETERLFHATNTPPQPGQTLFAQVRAGVLAYLQYDEHHPHGAWAAYLGMGRSDPL 120 Query 121 LLGIDDEAKNRQMEHIMSRIAEVVSGIDRDNTLDPEVERDLRVIIHGWLAFTFELCRQRI 180 L GI+D +RQ I+ RI V G +D ++ERDLR ++GWLAFTFE+CRQR+ Sbjct 121 LRGIEDIDNDRQANRIIDRITTAVGG-----GIDSKLERDLRATVYGWLAFTFEMCRQRL 175 Query 181 MDPSTDAERLADACAHALLDAISRLPQIPAELADAMATAR 220 MD S DA+ +A CAH L+DA+ R+P IPA LA+A+A R Sbjct 176 MDASLDADFIAGLCAHGLMDAVGRVPGIPAALAEAVAVDR 215 >gi|169630729|ref|YP_001704378.1| TetR family transcriptional regulator [Mycobacterium abscessus ATCC 19977] gi|169242696|emb|CAM63724.1| Putative TetR-family transcriptional regulator [Mycobacterium abscessus] Length=226 Score = 192 bits (487), Expect = 3e-47, Method: Compositional matrix adjust. Identities = 96/217 (45%), Positives = 145/217 (67%), Gaps = 6/217 (2%) Query 2 ATARRRLSPQDRRAELLALGAEVFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFFA 61 A+ RRRL+P+DRRAELL G ++FG+R YD+VR+DE+AE+AGVSRAL+Y YFPDKRAF+ Sbjct 13 ASPRRRLTPEDRRAELLDFGTQLFGERHYDDVRMDEVAEQAGVSRALLYRYFPDKRAFYT 72 Query 62 AVVKDEADRLYAATNKAPA-PGMTMFEEIRTGVLAYMAYHQQNPEAAWAAYVGLGRSDPV 120 AV++ E DRLY AT ++ FE +R +L Y+ Y +++P A + + +DP Sbjct 73 AVMQAEYDRLYDATISLDMDQTLSGFERLRRTLLVYLHYQEEHPFAPVTVFRMIDSADPT 132 Query 121 LLGIDDEAKNRQMEHIMSRIAEVVSGIDRDNTLDPEVERDLRVIIHGWLAFTFELCRQRI 180 ++ I+ + ++Q + IM+ + + V+G + + P + DL+V+I WLAF EL RQR Sbjct 133 VMAIEQQEYDKQTDRIMA-VVDHVAG----DEMTPALVTDLKVVIRAWLAFNQELARQRA 187 Query 181 MDPSTDAERLADACAHALLDAISRLPQIPAELADAMA 217 ++P D + LAD AHA++DA+ R+P IP + D M Sbjct 188 LNPELDVDWLADTSAHAMIDAVRRMPNIPQAVVDLMG 224 >gi|21219322|ref|NP_625101.1| TetR family transcriptional regulator [Streptomyces coelicolor A3(2)] gi|6714735|emb|CAB66200.1| putative TetR-family transcriptional regulatory protein [Streptomyces coelicolor A3(2)] Length=205 Score = 132 bits (333), Expect = 3e-29, Method: Compositional matrix adjust. Identities = 78/202 (39%), Positives = 121/202 (60%), Gaps = 13/202 (6%) Query 5 RRRLSPQDRRAELLALGAEVFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFFAAVV 64 RRRLS +RR +LL++GA +F + PYDEV I+++AE AGVSR L+YHYFP+KR FFAAVV Sbjct 13 RRRLSTGERREQLLSVGARLFSESPYDEVWIEQVAEIAGVSRGLLYHYFPNKRDFFAAVV 72 Query 65 KDEADRLYAATNKAPAPGMTMFEEIRTGVLAYMAYHQQNPEAAWAAYVGLGRSDPVLLGI 124 + E++R+ T A PG+ + E++ G+ AY+ Y + + Y R+D Sbjct 73 ERESERMLRMT--AAVPGVPVREQLTAGLDAYLEYVRAHAH----GYRAFHRAD----AA 122 Query 125 DDEAKNRQMEHIM-SRIAEVVSGIDRDNTLDPEVER--DLRVIIHGWLAFTFELCRQRIM 181 D A R + + ++ ++++ + D P E D+R+ + GWLAFT +C + + Sbjct 123 GDRAVRRVYQKALAAQERQILAALAADPEFGPAFEERGDVRLAVRGWLAFTTAVCLEWLR 182 Query 182 DPSTDAERLADACAHALLDAIS 203 DP E++ D CA ALL A++ Sbjct 183 DPEPAREQVRDLCARALLGAVA 204 >gi|289773529|ref|ZP_06532907.1| TetR family transcriptional regulator [Streptomyces lividans TK24] gi|289703728|gb|EFD71157.1| TetR family transcriptional regulator [Streptomyces lividans TK24] Length=202 Score = 132 bits (332), Expect = 4e-29, Method: Compositional matrix adjust. Identities = 78/202 (39%), Positives = 121/202 (60%), Gaps = 13/202 (6%) Query 5 RRRLSPQDRRAELLALGAEVFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFFAAVV 64 RRRLS +RR +LL++GA +F + PYDEV I+++AE AGVSR L+YHYFP+KR FFAAVV Sbjct 10 RRRLSTGERREQLLSVGARLFSESPYDEVWIEQVAEIAGVSRGLLYHYFPNKRDFFAAVV 69 Query 65 KDEADRLYAATNKAPAPGMTMFEEIRTGVLAYMAYHQQNPEAAWAAYVGLGRSDPVLLGI 124 + E++R+ T A PG+ + E++ G+ AY+ Y + + Y R+D Sbjct 70 ERESERMLRMT--AAVPGVPVREQLTAGLDAYLEYVRAHAH----GYRAFHRAD----AA 119 Query 125 DDEAKNRQMEHIM-SRIAEVVSGIDRDNTLDPEVER--DLRVIIHGWLAFTFELCRQRIM 181 D A R + + ++ ++++ + D P E D+R+ + GWLAFT +C + + Sbjct 120 GDRAVRRVYQKALAAQERQILAALAADPEFGPAFEERGDVRLAVRGWLAFTTAVCLEWLR 179 Query 182 DPSTDAERLADACAHALLDAIS 203 DP E++ D CA ALL A++ Sbjct 180 DPEPAREQVRDLCARALLGAVA 201 >gi|29833969|ref|NP_828603.1| TetR family transcriptional regulator [Streptomyces avermitilis MA-4680] gi|29611094|dbj|BAC75138.1| putative TetR-family transcriptional regulator [Streptomyces avermitilis MA-4680] Length=202 Score = 128 bits (322), Expect = 5e-28, Method: Compositional matrix adjust. Identities = 75/199 (38%), Positives = 115/199 (58%), Gaps = 7/199 (3%) Query 5 RRRLSPQDRRAELLALGAEVFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFFAAVV 64 RRRLS ++RR +LL++GA +F + PYDEV I+++AE AGVSR L+YHYFP KR FFAAVV Sbjct 10 RRRLSTEERREQLLSVGARLFSESPYDEVWIEQVAEIAGVSRGLLYHYFPTKRDFFAAVV 69 Query 65 KDEADRLYAATNKAPAPGMTMFEEIRTGVLAYMAYHQQNPEAAWAAYVGLGRSDPVLLGI 124 + E+ R+ T A PG+ + E++ G+ ++ Y + + A + D + + Sbjct 70 ERESGRMLRMT--AAVPGIPVREQLGAGLDVFLEYVEAHAHGFRAFHRADAAGDQAVRTV 127 Query 125 DDEAKNRQMEHIMSRIAEVVSGIDRDNTLDPEVERDLRVIIHGWLAFTFELCRQRIMDPS 184 +A Q I++ +A D + PE E +LR+ + GWLAFT +C + + Sbjct 128 YRQALAAQERQILAALA-----ADPEIGRSPEEEPELRIAVRGWLAFTTAVCLEWLRGAE 182 Query 185 TDAERLADACAHALLDAIS 203 E++ D CA ALL I+ Sbjct 183 LTREQVRDLCARALLGVIA 201 >gi|302562300|ref|ZP_07314642.1| TetR-family transcriptional regulatory protein [Streptomyces griseoflavus Tu4000] gi|302479918|gb|EFL43011.1| TetR-family transcriptional regulatory protein [Streptomyces griseoflavus Tu4000] Length=202 Score = 127 bits (319), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 76/201 (38%), Positives = 117/201 (59%), Gaps = 11/201 (5%) Query 5 RRRLSPQDRRAELLALGAEVFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFFAAVV 64 RRRLS +RR +LL++GA +F + PYDEV I+++AE AGVSR L+YHYFP KR FFAAVV Sbjct 10 RRRLSTGERREQLLSVGARLFSESPYDEVWIEQVAEIAGVSRGLLYHYFPTKRDFFAAVV 69 Query 65 KDEADRLYAATNKAPAPGMTMFEEIRTGVLAYMAYHQQNPEAAWAAYVGLGRSDPVLLGI 124 + E++R+ T A PG+ + E++ G+ AY+ Y EA Y R+D Sbjct 70 ERESERMLRMT--AAVPGVPVREQLTAGLDAYLEY----VEAHAHGYRAFHRADAA---G 120 Query 125 DDEAKNRQMEHIMSRIAEVVSGIDRDNTLDPEVER--DLRVIIHGWLAFTFELCRQRIMD 182 D + + ++ ++++ + +D P +E D R+ + GWLAFT +C + + Sbjct 121 DRAVRRVYRRALAAQERQILAALAQDPEYGPALEARPDTRLAVRGWLAFTTAVCLEWLRG 180 Query 183 PSTDAERLADACAHALLDAIS 203 D E++ D CA ALL ++ Sbjct 181 SGPDREQVRDLCARALLGVLT 201 >gi|291435483|ref|ZP_06574873.1| TetR-family transcriptional regulatory protein [Streptomyces ghanaensis ATCC 14672] gi|291338378|gb|EFE65334.1| TetR-family transcriptional regulatory protein [Streptomyces ghanaensis ATCC 14672] Length=202 Score = 127 bits (318), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 78/202 (39%), Positives = 120/202 (60%), Gaps = 13/202 (6%) Query 5 RRRLSPQDRRAELLALGAEVFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFFAAVV 64 RRRLS +RR +LL++GA +F + PYD+V I+++AE AGVSR L+YHYFP KR FFAAVV Sbjct 10 RRRLSTGERREQLLSVGARLFSESPYDDVWIEQVAEIAGVSRGLLYHYFPTKRDFFAAVV 69 Query 65 KDEADRLYAATNKAPAPGMTMFEEIRTGVLAYMAYHQQNPEAAWAAYVGLGRSDPVLLGI 124 + E++R+ T A PG+ + E + G+ AY++Y EA Y L R+D V Sbjct 70 ERESERMLRMT--AGVPGVPVRERLAAGLDAYLSY----VEAHAHGYRALHRADAV---- 119 Query 125 DDEAKNRQMEHIM-SRIAEVVSGIDRDNTLDPEVER--DLRVIIHGWLAFTFELCRQRIM 181 D A R + ++ ++++ + D P +E D R+ + GWLAFT +C + + Sbjct 120 GDRAVRRLYRRALAAQERQILAALAEDPEFGPALEARPDTRLAVRGWLAFTTAVCLEWLR 179 Query 182 DPSTDAERLADACAHALLDAIS 203 + + E++ D CA ALL ++ Sbjct 180 GSALEREQVRDLCARALLGVLA 201 >gi|117165014|emb|CAJ88566.1| putative TetR-family transcriptional regulatory protein [Streptomyces ambofaciens ATCC 23877] Length=202 Score = 124 bits (312), Expect = 7e-27, Method: Compositional matrix adjust. Identities = 76/202 (38%), Positives = 121/202 (60%), Gaps = 13/202 (6%) Query 5 RRRLSPQDRRAELLALGAEVFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFFAAVV 64 RRRLS +RR +LL++GA +F + PYD+V I+++AE AGVSR L+YHYFP+KR FFAA+V Sbjct 10 RRRLSTGERREQLLSVGARLFSESPYDDVWIEQVAEIAGVSRGLLYHYFPNKRDFFAAIV 69 Query 65 KDEADRLYAATNKAPAPGMTMFEEIRTGVLAYMAYHQQNPEAAWAAYVGLGRSDPVLLGI 124 + E++R+ T A PG+ + E++ G+ AY+ Y + + Y R+D Sbjct 70 ERESERMLRMT--AAVPGLPVREQLTAGLDAYLEYVRAHAH----GYRAFHRAD----AA 119 Query 125 DDEAKNRQMEHIM-SRIAEVVSGIDRDNTLDPEV-ER-DLRVIIHGWLAFTFELCRQRIM 181 D+A R + ++ ++++ + D P ER D+R+ + GWLAFT +C + + Sbjct 120 GDQAVRRVYRKALAAQERQILAALAADPEFGPLFGERTDVRLAVRGWLAFTTAVCLEWLR 179 Query 182 DPSTDAERLADACAHALLDAIS 203 + E++ D CA ALL AI+ Sbjct 180 ESEPAPEQVRDLCARALLGAIA 201 >gi|290955499|ref|YP_003486681.1| TetR family transcriptional regulator [Streptomyces scabiei 87.22] gi|260645025|emb|CBG68111.1| putative TetR-family transcriptional regulatory protein [Streptomyces scabiei 87.22] Length=202 Score = 122 bits (306), Expect = 4e-26, Method: Compositional matrix adjust. Identities = 73/199 (37%), Positives = 115/199 (58%), Gaps = 7/199 (3%) Query 5 RRRLSPQDRRAELLALGAEVFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFFAAVV 64 RRRLS ++RR +LLA+GA +F + PYD+V I+++AE AGVSR L+YHYFP+KR FFAAVV Sbjct 10 RRRLSTEERREQLLAVGARLFSESPYDDVWIEQVAEIAGVSRGLLYHYFPNKRDFFAAVV 69 Query 65 KDEADRLYAATNKAPAPGMTMFEEIRTGVLAYMAYHQQNPEAAWAAYVGLGRSDPVLLGI 124 + E++R+ PAPG + E + G+ A++A+ +++ A + D + + Sbjct 70 ERESERMLRIMT--PAPGRSARERLANGLDAFLAHVEEHAHGFRAFHRADATGDQAVRRV 127 Query 125 DDEAKNRQMEHIMSRIAEVVSGIDRDNTLDPEVERDLRVIIHGWLAFTFELCRQRIMDPS 184 A Q I++ +A S + LD E +R+ + GWLAFT +C + + Sbjct 128 YQRALAVQEAQILAALA---SDAEFRAALDGRPE--MRLAVRGWLAFTTAVCLEWLRGAE 182 Query 185 TDAERLADACAHALLDAIS 203 E++ D CA AL ++ Sbjct 183 LSREQVRDLCARALFGVLT 201 >gi|302555964|ref|ZP_07308306.1| TetR family transcriptional regulator [Streptomyces viridochromogenes DSM 40736] gi|302473582|gb|EFL36675.1| TetR family transcriptional regulator [Streptomyces viridochromogenes DSM 40736] Length=202 Score = 120 bits (302), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 72/202 (36%), Positives = 118/202 (59%), Gaps = 13/202 (6%) Query 5 RRRLSPQDRRAELLALGAEVFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFFAAVV 64 RRRLS ++RR +LL++GA +F + PYD+V I+++AE AGVSR L+YHYFP KR FFAAVV Sbjct 10 RRRLSTEERREQLLSVGARLFSENPYDDVWIEQVAEIAGVSRGLLYHYFPTKRDFFAAVV 69 Query 65 KDEADRLYAATNKAPAPGMTMFEEIRTGVLAYMAYHQQNPEAAWAAYVGLGRSDPVLLGI 124 + E++R+ T A PG+ + E++ G+ ++ Y EA Y R+D Sbjct 70 ERESERMLRMT--AAVPGVPVREQLPAGLDTFLEY----VEAHAHGYRAFHRAD----AA 119 Query 125 DDEAKNRQMEHIM-SRIAEVVSGIDRDNTLDP--EVERDLRVIIHGWLAFTFELCRQRIM 181 D+A R + + ++ ++++ + D P EV ++R+ + GWLAF +C + + Sbjct 120 GDQAVRRVYQRALAAQERQILAALAEDPEFGPAFEVRPEVRLAVRGWLAFITSVCLEWLR 179 Query 182 DPSTDAERLADACAHALLDAIS 203 E++ + CA ALL ++ Sbjct 180 GTELSREQVRELCARALLGVLT 201 >gi|302529370|ref|ZP_07281712.1| TetR family transcriptional regulator [Streptomyces sp. AA4] gi|302438265|gb|EFL10081.1| TetR family transcriptional regulator [Streptomyces sp. AA4] Length=193 Score = 117 bits (294), Expect = 8e-25, Method: Compositional matrix adjust. Identities = 69/203 (34%), Positives = 108/203 (54%), Gaps = 13/203 (6%) Query 5 RRRLSPQDRRAELLALGAEVFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFFAAVV 64 R RLS + RR +LL +GA +F RPYDEV I+E+AE AGVSR L+YHYFP K+ FFAA+V Sbjct 2 RTRLSTEQRRQQLLTIGAGLFAGRPYDEVWIEEVAEIAGVSRGLLYHYFPTKKDFFAAIV 61 Query 65 KDEADRLYAATNKAPAPGMTMFEEIRTGVLAYMAYHQQNPEAAWAAYVGLGRSDPVLLGI 124 +++ D+L + P P + + E++R G+ Y+ + + +P+ + G +D + I Sbjct 62 REQRDQLLKMSE--PDPALPVAEQLRAGLEVYLEFARTHPDGYRIVHRSAGDADREIREI 119 Query 125 DDEAKNRQMEHIMSRIAEVVSGIDRDNTLDPEVERDLRVIIHGWLAFTFELCRQRIMDPS 184 + + I+S + + L P V ++ + GWL+F L + +P Sbjct 120 CEAGMAANADRILSAV----------SLLRP-VTPTTQLAVRGWLSFVATLILDWLDEPK 168 Query 185 TDAERLADACAHALLDAISRLPQ 207 E L D CA L A+ P Sbjct 169 ISTEELRDLCARTLFAAVDVDPH 191 >gi|297204231|ref|ZP_06921628.1| TetR-family transcriptional regulator [Streptomyces sviceus ATCC 29083] gi|197714077|gb|EDY58111.1| TetR-family transcriptional regulator [Streptomyces sviceus ATCC 29083] Length=202 Score = 117 bits (293), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 74/204 (37%), Positives = 112/204 (55%), Gaps = 19/204 (9%) Query 5 RRRLSPQDRRAELLALGAEVFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFFAAVV 64 RRRLS ++RR +LL +GA +F + PYD+V I+++AE AGVSR L+YHYF K+ FFAAVV Sbjct 10 RRRLSTEERREQLLTVGARLFSESPYDDVWIEQVAEIAGVSRGLLYHYFSTKQDFFAAVV 69 Query 65 KDEADRLYAATNKAPAPGMTMFEEIRTGVLAYMAYHQQNPEAAWAAYVGLGRSDPVLLGI 124 + E++R+ A T A PG+ + E++ G+ Y+ Y + A + D + + Sbjct 70 ERESERMLAMT--AAVPGVPVREQLTAGLDTYLEYVHTHAHGFRAFHRADAAGDQAVRRV 127 Query 125 DDEAKNRQMEHIMSRIAEVVSGIDRDNTLDPEV-----ER-DLRVIIHGWLAFTFELCRQ 178 A Q I++ +A DPE ER DL++ + GWLAFT +C + Sbjct 128 YQRALAAQERQILAALAA-----------DPEFGAQAQERPDLQLAVRGWLAFTTAVCLE 176 Query 179 RIMDPSTDAERLADACAHALLDAI 202 + E++ D CA ALL + Sbjct 177 WLRGSDLSREQVRDLCARALLGVL 200 >gi|226364135|ref|YP_002781917.1| TetR family transcriptional regulator [Rhodococcus opacus B4] gi|226242624|dbj|BAH52972.1| putative TetR family transcriptional regulator [Rhodococcus opacus B4] Length=202 Score = 114 bits (286), Expect = 7e-24, Method: Compositional matrix adjust. Identities = 75/200 (38%), Positives = 109/200 (55%), Gaps = 17/200 (8%) Query 1 MATARRRLSPQDRRAELLALGAEVFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFF 60 M +ARRRL+P+ RRA+LL +GA +F RPY++V I+E+AE A VSR LMYHYFP KR FF Sbjct 9 MTSARRRLAPEQRRAQLLDIGARLFADRPYEDVWIEEVAELAEVSRGLMYHYFPTKRDFF 68 Query 61 AAVVKDEADRLYAATNKAPAPGMTMFEEIRTGVLAYMAYHQQNPEAAWAAYVGLGRSDPV 120 AA+V+ E++RL T AP + + E++ G+ AY + + A G +D Sbjct 69 AAIVERESERLLDVT--APDSTLPVEEQVAAGLDAYFEHVASHRHGVRAINHGALSADAD 126 Query 121 LLGIDDEAKNRQMEHIMSRIAEVVSGIDRDNTLD-PEVERDL-RVIIHGWLAFTFELCRQ 178 + I + + Q I+ + LD PE ER+L V + GW+AF +C Sbjct 127 IRAIVERELDAQQRRIV-------------DALDPPEGERELVGVAVRGWIAFVRAVCMD 173 Query 179 RIMDPSTDAERLADACAHAL 198 + PS L + C +L Sbjct 174 WLDHPSIAEAELRELCLRSL 193 >gi|111021600|ref|YP_704572.1| TetR family transcriptional regulator [Rhodococcus jostii RHA1] gi|110821130|gb|ABG96414.1| probable transcriptional regulator, TetR family protein [Rhodococcus jostii RHA1] Length=194 Score = 112 bits (281), Expect = 3e-23, Method: Compositional matrix adjust. Identities = 74/200 (37%), Positives = 109/200 (55%), Gaps = 17/200 (8%) Query 1 MATARRRLSPQDRRAELLALGAEVFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFF 60 M +ARRRL+P+ RRA+LL +GA +F RPY++V I+E+AE A VSR LMYHYFP KR FF Sbjct 1 MTSARRRLAPEQRRAQLLDIGARLFADRPYEDVWIEEVAELAEVSRGLMYHYFPTKRDFF 60 Query 61 AAVVKDEADRLYAATNKAPAPGMTMFEEIRTGVLAYMAYHQQNPEAAWAAYVGLGRSDPV 120 AA+V+ E++RL T AP + + E++ G+ AY + + A G +D Sbjct 61 AAIVERESERLLDVT--APDSTLPVEEQVAAGLDAYFEHVASHRHGVRAINHGALSADAD 118 Query 121 LLGIDDEAKNRQMEHIMSRIAEVVSGIDRDNTLD-PEVERDL-RVIIHGWLAFTFELCRQ 178 + I + + Q I+ + LD P+ ER+L V + GW+AF +C Sbjct 119 IRAIVERELDAQQRRIV-------------DALDPPDGERELVGVAVRGWIAFVRAVCMD 165 Query 179 RIMDPSTDAERLADACAHAL 198 + PS L + C +L Sbjct 166 WLDHPSIAEGELRELCLRSL 185 >gi|329936443|ref|ZP_08286208.1| TetR family transcriptional regulator [Streptomyces griseoaurantiacus M045] gi|329304239|gb|EGG48120.1| TetR family transcriptional regulator [Streptomyces griseoaurantiacus M045] Length=201 Score = 109 bits (272), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 71/205 (35%), Positives = 109/205 (54%), Gaps = 26/205 (12%) Query 8 LSPQDRRAELLALGAEVFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFFAAVVKDE 67 LS ++RR +LL++GA +F PY++VRI+ +AE AGVSR L+YHYFP KR FFAAVV E Sbjct 13 LSTEERREQLLSVGARLFSDDPYEDVRIERVAELAGVSRGLLYHYFPTKRDFFAAVVARE 72 Query 68 ADRLYAATNKAPAPGMTMFEEIRTGV---LAYMAYHQQNPEAAWAAYVGLGRSDPVLLGI 124 ++R+ T A PG+++ ++ G+ L Y+A H A A Sbjct 73 SERMLRMT--AAVPGVSVRAQLPAGLDIFLGYVAEHAHGFRAFHRA-------------- 116 Query 125 DDEAKNRQMEHIMSRIA-----EVVSGIDRDNTLDPEVER-DLRVIIHGWLAFTFELCRQ 178 D A +R + + R ++++ + D P E +LR+ + GWLAFT +C + Sbjct 117 -DAAGDRAVRQVYRRSLAAQERQILAALAADPEFGPAGEGPELRMAVRGWLAFTTAVCLE 175 Query 179 RIMDPSTDAERLADACAHALLDAIS 203 + E++ D C AL A+S Sbjct 176 WLRHGELSREQVRDLCVRALWGAVS 200 >gi|229494211|ref|ZP_04387974.1| TetR-family transcriptional regulatory protein [Rhodococcus erythropolis SK121] gi|229318573|gb|EEN84431.1| TetR-family transcriptional regulatory protein [Rhodococcus erythropolis SK121] Length=195 Score = 108 bits (270), Expect = 5e-22, Method: Compositional matrix adjust. Identities = 70/203 (35%), Positives = 105/203 (52%), Gaps = 13/203 (6%) Query 1 MATARRRLSPQDRRAELLALGAEVFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFF 60 M R+RL + RR +LL +GA++F R Y++V I+E+AE AGVSR LMYHYFP KR FF Sbjct 1 MVAPRKRLDREQRRTQLLDIGAQLFADRSYEDVWIEEVAEIAGVSRGLMYHYFPTKRDFF 60 Query 61 AAVVKDEADRLYAATNKAPAPGMTMFEEIRTGVLAYMAYHQQNPEAAWAAYVGLGRSDPV 120 AA+V+ E+ L T AP + + E++ G+ AY AY + + A VG ++ Sbjct 61 AAIVERESQHLLEVT--APDATLPVREQVAAGLDAYFAYVKSHSRGVRAINVGTLSAEAG 118 Query 121 LLGIDDEAKNRQMEHIMSRIAEVVSGIDRDNTLDPEVERDLRVIIHGWLAFTFELCRQRI 180 + I + R++E RI + + + E + V + GW+AF +C + Sbjct 119 IRAIVE----RELEQQQIRILDALG-------FEGERRQLAAVAVRGWIAFVRAVCLDWL 167 Query 181 MDPSTDAERLADACAHALLDAIS 203 PS E L C L A+ Sbjct 168 DQPSIPQEELRVICLRTLSGALG 190 >gi|226304386|ref|YP_002764344.1| TetR family transcriptional regulator [Rhodococcus erythropolis PR4] gi|226183501|dbj|BAH31605.1| putative TetR family transcriptional regulator [Rhodococcus erythropolis PR4] Length=195 Score = 108 bits (270), Expect = 5e-22, Method: Compositional matrix adjust. Identities = 70/203 (35%), Positives = 105/203 (52%), Gaps = 13/203 (6%) Query 1 MATARRRLSPQDRRAELLALGAEVFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFF 60 M R+RL + RR +LL +GA++F R Y++V I+E+AE AGVSR LMYHYFP KR FF Sbjct 1 MVAPRKRLDREQRRTQLLDIGAQLFADRSYEDVWIEEVAEIAGVSRGLMYHYFPTKRDFF 60 Query 61 AAVVKDEADRLYAATNKAPAPGMTMFEEIRTGVLAYMAYHQQNPEAAWAAYVGLGRSDPV 120 AA+V+ E+ L T AP + + E++ G+ AY AY + + A VG ++ Sbjct 61 AAIVERESQHLLEVT--APDATLPVREQVAAGLDAYFAYVKSHSRGVRAINVGTLSAEAG 118 Query 121 LLGIDDEAKNRQMEHIMSRIAEVVSGIDRDNTLDPEVERDLRVIIHGWLAFTFELCRQRI 180 + I + R++E RI + + + E + V + GW+AF +C + Sbjct 119 IRAIVE----RELEQQQIRILDALE-------FEGERRQIAAVAVRGWIAFVRAVCLDWL 167 Query 181 MDPSTDAERLADACAHALLDAIS 203 PS E L C L A+ Sbjct 168 DQPSIPQEELRVICLRTLSGALG 190 >gi|302538928|ref|ZP_07291270.1| predicted protein [Streptomyces sp. C] gi|302447823|gb|EFL19639.1| predicted protein [Streptomyces sp. C] Length=211 Score = 105 bits (261), Expect = 6e-21, Method: Compositional matrix adjust. Identities = 69/201 (35%), Positives = 102/201 (51%), Gaps = 12/201 (5%) Query 5 RRRLSPQDRRAELLALGAEVFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFFAAVV 64 R+RLSP +RR +LL + A +F +PYD+V ++ +AE AGVSRAL+Y +FP KR FAA+ Sbjct 12 RKRLSPAERRTQLLGVAARLFAAQPYDDVLMEHVAEHAGVSRALLYQHFPGKRDLFAALY 71 Query 65 KDEADRLYAATNKAPAPGMTMFEEIRTGVLAYMAYHQQNPEAAWAAYVGLGRSDPVLLGI 124 AD+L A T PA T+ E++ G+ A++AY +N AA L DPV+ I Sbjct 72 AQVADQLLAQTRLDPAD--TLVEQLTQGLDAHIAYFAENRNTVLAANRVLA-GDPVIQTI 128 Query 125 DDEAKNRQMEHIMSRIAEVVSGIDRDNTLDPEVERDLRVIIHGWLAFTFELCRQRIMDPS 184 + E ++ + + G R + ++ WL F LC + + Sbjct 129 ITGELDALRERLLG-VLPLADGATRRAAVSG--------VLKSWLVFVQVLCVDWLTQQT 179 Query 185 TDAERLADACAHALLDAISRL 205 L D C AL+ AI L Sbjct 180 CTRAELRDVCVGALIGAIRPL 200 >gi|297153955|gb|ADI03667.1| transcriptional regulator, TetR family protein [Streptomyces bingchenggensis BCW-1] Length=219 Score = 103 bits (257), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 71/202 (36%), Positives = 109/202 (54%), Gaps = 15/202 (7%) Query 5 RRRLSPQDRRAELLALGAEVFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFFAAVV 64 R+RL+P DRRA+LLA+GA +F PY +V ++++AE+AGVSRAL+Y +FP K A FAAV Sbjct 4 RQRLTPADRRAQLLAVGARLFAAHPYADVLMEDVAEQAGVSRALLYRHFPSKHALFAAVY 63 Query 65 KDEADRLYAATNKAPAPGMTMFEEIRTGVLAYMAYHQQNPEAAWAAYVGLGRSDPVLLGI 124 + AD+L A T PA ++ E++ G+ ++ Y N A AA L DPV+ I Sbjct 64 QQAADQLLAETRLDPAD--SLVEQLIQGMDVHLDYFVANRNAVLAANRVLA-GDPVIQTI 120 Query 125 DDEAKNRQMEHIMSRIAEVVSGIDRDNTLDPEVERD-LRVIIHGWLAFTFELCRQRIMDP 183 +++ + +R+ V+ D RD + ++ WL F LC + Sbjct 121 ----MTNELDALRARLLAVLPLADAG-------ARDAVSGVLKSWLVFVQVLCVDWLSHE 169 Query 184 STDAERLADACAHALLDAISRL 205 + +L D C A+L A+ L Sbjct 170 TCTRTQLRDICIGAVLGALRPL 191 >gi|302556344|ref|ZP_07308686.1| TetR-family transcriptional regulator [Streptomyces viridochromogenes DSM 40736] gi|302473962|gb|EFL37055.1| TetR-family transcriptional regulator [Streptomyces viridochromogenes DSM 40736] Length=209 Score = 103 bits (257), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 71/208 (35%), Positives = 108/208 (52%), Gaps = 14/208 (6%) Query 4 ARRRLSPQDRRAELLALGAEVFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFFAAV 63 +R+RL+P RR +LLA+GA +F PY +V ++ +AE AGVSRAL+Y +FP K A FAAV Sbjct 3 SRQRLTPAARREQLLAVGARLFAAHPYADVLMEAVAEEAGVSRALLYRHFPSKHALFAAV 62 Query 64 VKDEADRLYAATNKAPAPGMTMFEEIRTGVLAYMAYHQQNPEAAWAAYVGLGRSDPVLLG 123 + AD+L A T PA ++ E++ G+ ++ Y N A AA L DPV+ Sbjct 63 YQQAADQLLADTRLDPAD--SLVEQLTQGMDVHLDYFVANRNAVLAANRVLA-GDPVIQT 119 Query 124 IDDEAKNRQMEHIMSRIAEVVSGIDRDNTLDPEVERDLRVIIHGWLAFTFELCRQRIMDP 183 I +++ + +R+ V+ D + ++ WL F LC + Sbjct 120 I----MTNELDALRTRLLAVLPLADE------SAREAVSGVLKSWLVFVQVLCVDWLTHE 169 Query 184 STDAERLADACAHALLDAI-SRLPQIPA 210 + +L D C A+L A+ LPQ PA Sbjct 170 TCTRSQLRDVCVGAVLGALRPLLPQDPA 197 >gi|302528636|ref|ZP_07280978.1| predicted protein [Streptomyces sp. AA4] gi|302437531|gb|EFL09347.1| predicted protein [Streptomyces sp. AA4] Length=197 Score = 99.0 bits (245), Expect = 4e-19, Method: Compositional matrix adjust. Identities = 69/201 (35%), Positives = 99/201 (50%), Gaps = 14/201 (6%) Query 5 RRRLSPQDRRAELLALGAEVFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFFAAVV 64 RRRL P RRAELL + A F +PYD V++++IAE+AGVSRAL+Y +F K FAAV Sbjct 4 RRRLDPAQRRAELLEVAAREFAAKPYDAVQMEQIAEQAGVSRALLYRHFHAKHDLFAAVY 63 Query 65 KDEADRLYAATNKAPAPGMTMFEEIRTGVLAYMAYHQQNPEAAWAAYVGLGRSDPVLLGI 124 + ADRL A T P P + + E+I G+ + Y N AA L DPV+ Sbjct 64 RQAADRLLADTE--PDPDVPLTEQIALGLEVHFDYFLANRNTVLAANRTLA-GDPVV--- 117 Query 125 DDEAKNRQMEHIMSRIAEVVSGIDRDNTLDPEVERDLRVIIHGWLAFTFELCRQRIMDPS 184 A ++ + R+ + + L L + GWL F LC + ++ + Sbjct 118 -QAAITDELTVLRQRLVDA-------SGLTGHAGELLSAALTGWLQFVRVLCVEWLLTDA 169 Query 185 TDAERLADACAHALLDAISRL 205 L D C AL A+ ++ Sbjct 170 MSRAELRDLCVGALTGALEKI 190 >gi|328884825|emb|CCA58064.1| Transcriptional regulator, TetR family [Streptomyces venezuelae ATCC 10712] Length=201 Score = 99.0 bits (245), Expect = 5e-19, Method: Compositional matrix adjust. Identities = 67/202 (34%), Positives = 107/202 (53%), Gaps = 15/202 (7%) Query 5 RRRLSPQDRRAELLALGAEVFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFFAAVV 64 R+RL+P DRRA+LLA+GA +F PY +V ++++AE AGVSRAL+Y +FP K A FAAV Sbjct 4 RQRLTPADRRAQLLAVGARLFAAHPYADVLMEDVAEAAGVSRALLYRHFPSKHALFAAVY 63 Query 65 KDEADRLYAATNKAPAPGMTMFEEIRTGVLAYMAYHQQNPEAAWAAYVGLGRSDPVLLGI 124 + AD+L A T A ++ E++ G+ ++ Y N A A L DP++ I Sbjct 64 RQAADQLLADTRFETAD--SLVEQLTQGLDVHLDYFVANRNAVLTANRVLA-GDPLIQTI 120 Query 125 DDEAKNRQMEHIMSRIAEVVSGIDRDNTLDPEVERD-LRVIIHGWLAFTFELCRQRIMDP 183 +++ + +R+ V+ D E R+ + ++ WL F LC + Sbjct 121 ----MTNELDALRARLLAVLPLAD-------ESAREAVSAVLKSWLVFVQVLCVDWLTHE 169 Query 184 STDAERLADACAHALLDAISRL 205 + +L D C A++ A+ L Sbjct 170 TCTRTQLRDVCIGAVVGALRPL 191 >gi|343928038|ref|ZP_08767503.1| putative TetR family transcriptional regulator [Gordonia alkanivorans NBRC 16433] gi|343762046|dbj|GAA14429.1| putative TetR family transcriptional regulator [Gordonia alkanivorans NBRC 16433] Length=211 Score = 93.6 bits (231), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 64/202 (32%), Positives = 98/202 (49%), Gaps = 21/202 (10%) Query 2 ATARRRLSPQDRRAELLALGAEVFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFFA 61 A+ R R+SP+ RR +LL G E+ RP +E+ ID IA+ AGVSRAL++HYF K+ + Sbjct 18 ASKRTRMSPEGRRDQLLEFGLEMVRDRPLEEITIDAIADAAGVSRALLFHYFASKQDYHV 77 Query 62 AVVKDEADRLYAATNKAPAPGMTMFEEI---RTGVLAYMAYHQQNPEAAWAAYVGLGRSD 118 A+ + +ADR+ A T P ++ + I + A++ + +N A A G SD Sbjct 78 AIAQAQADRMLACTE----PDASLGDPIAILTASMAAFVDFVSENRSAYTALIRGASSSD 133 Query 119 PVLLGIDDEAKNRQMEHIMSRIAEVVSG--IDRDNTLDPEVERDLRVIIHGWLAFTFELC 176 P M + R EV+ G +D EV + + +HGW+AF E Sbjct 134 PA------------MRDVFDRTREVMVGRVLDHAPAFGVEVTPTVVLSVHGWVAFVEETT 181 Query 177 RQRIMDPSTDAERLADACAHAL 198 + + P+ E L AL Sbjct 182 IRWLTSPTVTREDLLGLITAAL 203 >gi|256391154|ref|YP_003112718.1| TetR family transcriptional regulator [Catenulispora acidiphila DSM 44928] gi|256357380|gb|ACU70877.1| transcriptional regulator, TetR family [Catenulispora acidiphila DSM 44928] Length=194 Score = 90.1 bits (222), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 61/201 (31%), Positives = 97/201 (49%), Gaps = 14/201 (6%) Query 2 ATARRRLSPQDRRAELLALGAEVFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFFA 61 + RRRL P+ RR ELL GAE F +PYD+V +++IA GVSRAL+Y YFP KR FA Sbjct 3 SVTRRRLKPEQRREELLDAGAEFFATQPYDDVLMEDIAAHVGVSRALLYKYFPGKRELFA 62 Query 62 AVVKDEADRLYAATNKAPAPGMTMFEEIRTGVLAYMAYHQQNPEAAWAAYVGLGRSDPVL 121 A+ + A+RL N P + + E + + A++ Y + AA L DP++ Sbjct 63 AIYRRAAERLL--ENSHLDPDLPLAETVSAALDAHIDYFAAHRLTVLAANRTLA-GDPMI 119 Query 122 LGIDDEAKNRQMEHIMSRIAEVVSGIDRDNTLDPEVERDLRVIIHGWLAFTFELCRQRIM 181 I D+ ++ + +R+ + R I+ WL F E+C + + Sbjct 120 QAIIDD----ELAVLRARMLDAAGFTGR-------ARETASAILRAWLVFVREMCVEWLQ 168 Query 182 DPSTDAERLADACAHALLDAI 202 + + + + C L A+ Sbjct 169 SEAIERDEVRAVCLRTLSAAL 189 >gi|229493748|ref|ZP_04387530.1| regulatory protein, TetR [Rhodococcus erythropolis SK121] gi|229319348|gb|EEN85187.1| regulatory protein, TetR [Rhodococcus erythropolis SK121] Length=211 Score = 89.4 bits (220), Expect = 4e-16, Method: Compositional matrix adjust. Identities = 54/199 (28%), Positives = 104/199 (53%), Gaps = 16/199 (8%) Query 2 ATARRRLSPQDRRAELLALGAEVFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFFA 61 A R RL P RRA+L+ LGA + +RP +++ +++IA++AGVSR L++HYF K F Sbjct 5 AVKRTRLDPAQRRAQLIDLGARMLAERPLEQISVEDIADQAGVSRGLLFHYFASKSEFHL 64 Query 62 AVVKDEADRLYAATNKAPA--PGMTMFEEIRTGVLAYMAYHQQNPEAAWAAYVGLGRSDP 119 A+V+ ++++ T + + P +T+ R+ + +Y+ Y +N + G DP Sbjct 65 AIVRHSSEQMLQRTEPSESDDPMLTL----RSVLASYVDYVTENRNTYVSLLRGTASGDP 120 Query 120 VLLGIDDEAKNRQMEHIMSRIAEVVSGIDRDNTLDPEVERDLRVIIHGWLAFTFELCRQR 179 + + ++ ++ + + ++ ++ G+ R P+VE + + GW+AF E Sbjct 121 QMREVFEQTRDIMAKRTLDQLPKI--GLTR----TPQVE----LAVRGWIAFVEEATISW 170 Query 180 IMDPSTDAERLADACAHAL 198 + P+ E L D +L Sbjct 171 LRAPAITREELIDLTVQSL 189 >gi|226307610|ref|YP_002767570.1| TetR family transcriptional regulator [Rhodococcus erythropolis PR4] gi|226186727|dbj|BAH34831.1| putative TetR family transcriptional regulator [Rhodococcus erythropolis PR4] Length=209 Score = 89.4 bits (220), Expect = 4e-16, Method: Compositional matrix adjust. Identities = 54/199 (28%), Positives = 104/199 (53%), Gaps = 16/199 (8%) Query 2 ATARRRLSPQDRRAELLALGAEVFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFFA 61 A R RL P RRA+L+ LGA + +RP +++ +++IA++AGVSR L++HYF K F Sbjct 3 AVKRTRLDPAQRRAQLIDLGARMLAERPLEQISVEDIADQAGVSRGLLFHYFASKSEFHL 62 Query 62 AVVKDEADRLYAATNKAPA--PGMTMFEEIRTGVLAYMAYHQQNPEAAWAAYVGLGRSDP 119 A+V+ ++++ T + + P +T+ R+ + +Y+ Y +N + G DP Sbjct 63 AIVRHSSEQMLQRTEPSESDDPMLTL----RSVLASYVDYVTENRNTYVSLLRGTASGDP 118 Query 120 VLLGIDDEAKNRQMEHIMSRIAEVVSGIDRDNTLDPEVERDLRVIIHGWLAFTFELCRQR 179 + + ++ ++ + + ++ ++ G+ R P+VE + + GW+AF E Sbjct 119 QMREVFEQTRDIMAKRTLDQLPKI--GLTR----TPQVE----LAVRGWIAFVEEATISW 168 Query 180 IMDPSTDAERLADACAHAL 198 + P+ E L D +L Sbjct 169 LRAPAITREELIDLTVQSL 187 >gi|326333156|ref|ZP_08199404.1| putative transcriptional regulator, TetR family [Nocardioidaceae bacterium Broad-1] gi|325949047|gb|EGD41139.1| putative transcriptional regulator, TetR family [Nocardioidaceae bacterium Broad-1] Length=205 Score = 89.0 bits (219), Expect = 5e-16, Method: Compositional matrix adjust. Identities = 74/209 (36%), Positives = 99/209 (48%), Gaps = 21/209 (10%) Query 3 TARRRLSPQDRRAELLALGAEVFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFFAA 62 + R RL+P+ RR +LL LG +F + DE+ ID +A AG+SR L+YHYF DK AF A Sbjct 5 SQRTRLTPEQRREQLLDLGIRLFARHSLDEISIDVVAREAGISRGLLYHYFGDKMAFREA 64 Query 63 VVKDEADRLYAATNKAPAPGMTMFEEIRTGVLAYMAYHQQNPEAAWAAYVGLGR---SDP 119 VV+ AD L A T AP E + + AY+ + N E YV + R SDP Sbjct 65 VVRRAADALVAQT--APPSTGEPVERLLASMTAYVDFVDANYE----GYVSMVRGAASDP 118 Query 120 VLLGIDDEAKNRQMEHIMSRIAEVVSGIDRDNTLDPEVERDLRVIIHGWLAFTFELCRQR 179 VL I DEA I A+ V E R+++ GW A + EL Sbjct 119 VLREIYDEAFLALGLRIFDAGADFV-----------EDTPAARLVVRGWQAMSEELVLSW 167 Query 180 IMDPS-TDAERLADACAHALLDAISRLPQ 207 DP+ E L A +L + LP+ Sbjct 168 KADPAGLSREELLGMLASSLPVLLEMLPR 196 >gi|134100745|ref|YP_001106406.1| transcriptional regulator [Saccharopolyspora erythraea NRRL 2338] gi|291008331|ref|ZP_06566304.1| transcriptional regulator [Saccharopolyspora erythraea NRRL 2338] gi|133913368|emb|CAM03481.1| probable transcriptional regulator [Saccharopolyspora erythraea NRRL 2338] Length=455 Score = 88.2 bits (217), Expect = 9e-16, Method: Compositional matrix adjust. Identities = 54/145 (38%), Positives = 79/145 (55%), Gaps = 4/145 (2%) Query 5 RRRLSPQDRRAELLALGAEVFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFFAAVV 64 R RL+P DRR +LL +GA +F +RPYD+V+I+EIA RAGVSR LMY YF KR F AVV Sbjct 3 RTRLNPSDRRDQLLRIGARLFAERPYDDVQIEEIAARAGVSRGLMYRYFATKRELFRAVV 62 Query 65 KDEADRLYAAT---NKAPAPGMTMFEEIRTG-VLAYMAYHQQNPEAAWAAYVGLGRSDPV 120 ++R+ T APG EE T V ++ + + A + G +D Sbjct 63 GRASERVAEGTALEASGTAPGTATPEERLTAQVEMFLDLFDTDADLMRALHAGTASADEE 122 Query 121 LLGIDDEAKNRQMEHIMSRIAEVVS 145 + I + R +H++ + ++ S Sbjct 123 VRRIIAQGARRHEDHVLDVLEQLGS 147 >gi|333921585|ref|YP_004495166.1| TetR family transcriptional regulator [Amycolicicoccus subflavus DQS3-9A1] gi|333483806|gb|AEF42366.1| Transcriptional regulator, TetR family [Amycolicicoccus subflavus DQS3-9A1] Length=189 Score = 87.8 bits (216), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 62/172 (37%), Positives = 91/172 (53%), Gaps = 14/172 (8%) Query 5 RRRLSPQDRRAELLALGAEVFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFFAAVV 64 R RLS +DRR +L+ +G + RP E+ IDE+A AG+SR L++HYFP KR ++ AVV Sbjct 2 RTRLSAEDRRRQLIGIGLRLLVSRPIHELAIDEVAAEAGISRGLLFHYFPTKREYYIAVV 61 Query 65 KDEADRLYAATNKAPAPGMTMFEEIRTGVLAYMAYHQQNPEAAWAAYVGLGRSDPVLLGI 124 + +RL +AP G T E +R V ++ + Q+ E YV L R+ Sbjct 62 QAAGNRLLLHA-RAPDEGTTA-ERVRGIVDGFVQFIQRRRE----NYVALVRAGAG---- 111 Query 125 DDEAKNRQMEHIMSRIAEVVSGIDRDNTLDPEVERDLRVIIHGWLAFTFELC 176 DE I +RIA+ V ID +P + LR+++ GWLA E+ Sbjct 112 GDERVLEVFSSIRARIADRV--IDAMGIAEPSPQ--LRLVVRGWLAMAEEIA 159 >gi|54026673|ref|YP_120915.1| putative transcriptional regulator [Nocardia farcinica IFM 10152] gi|54018181|dbj|BAD59551.1| putative transcriptional regulator [Nocardia farcinica IFM 10152] Length=214 Score = 87.4 bits (215), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 64/213 (31%), Positives = 106/213 (50%), Gaps = 13/213 (6%) Query 2 ATARR-RLSPQDRRAELLALGAEVFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFF 60 TA+R RLSP++RR +L+ALGA + G+R +++ + EIA AG+SR L++HYFP K+ F Sbjct 11 GTAKRTRLSPEERRKQLIALGARMLGERAIEDISVSEIAAEAGISRGLLFHYFPTKQDFQ 70 Query 61 AAVVKDEADRLYAATNKAPAPGMTMFEEIRTGVLAYMAYHQQNPEAAWAAYVGLGRSDPV 120 A+V+ L G+T + +R + Y+ Y QN + A G +P Sbjct 71 LAIVRHANAELLERVTPDRTLGIT--DMVRDSIERYVDYVSQNRTSYLALLRGPTSVNPD 128 Query 121 LLGIDDEAKNRQMEHIMSRIAEVVSGIDRDNTLDPEVERDLRVIIHGWLAFTFELCRQRI 180 L + + ++ ++ I++ V+ DR L + + GW+AF E + Sbjct 129 LGPLVESTRDAIVQLILTEAPIEVAETDRPRLL---------LGMRGWIAFVEETTLTWL 179 Query 181 MDPSTDAERLADACAHALLDAISRL-PQIPAEL 212 E+L D +LL+ + L PQ+ A L Sbjct 180 RTEPIPREQLIDLLVDSLLNLAAALEPQLAAAL 212 >gi|111022972|ref|YP_705944.1| TetR family transcriptional regulator [Rhodococcus jostii RHA1] gi|110822502|gb|ABG97786.1| probable transcriptional regulator, TetR family protein [Rhodococcus jostii RHA1] Length=212 Score = 86.3 bits (212), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 54/182 (30%), Positives = 96/182 (53%), Gaps = 14/182 (7%) Query 5 RRRLSPQDRRAELLALGAEVFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFFAAVV 64 R RLSP+ RRA+L+ LGA++ +RP +++ +++IA++AGVSR L++HYF K F +V Sbjct 6 RTRLSPEQRRAQLIDLGAKMLAQRPLEQISVEDIADQAGVSRGLLFHYFASKHDFHLEIV 65 Query 65 KDEADRLYAATNKAPAPGMTM--FEEIRTGVLAYMAYHQQNPEAAWAAYVGLGRSDPVLL 122 + + + A T AP G + +R+ + +Y+ Y +N + G DP + Sbjct 66 RHTSSEMLARTAPAPYIGDARDPMQILRSVLASYVDYVSENRGTYVSLLRGTASGDPDMR 125 Query 123 GIDDEAKNRQMEHIMS-RIAEVVSGIDRDNTLDPEVERDLRVIIHGWLAFTFELCRQRIM 181 + +E + +MS R E + I + T R + + + GW+A+ E+ + Sbjct 126 AVFEETRA-----VMSARTLEQLPAIGVEPT------RAVELAVRGWIAYVEEVTITWLR 174 Query 182 DP 183 DP Sbjct 175 DP 176 >gi|226365478|ref|YP_002783261.1| TetR family transcriptional regulator [Rhodococcus opacus B4] gi|226243968|dbj|BAH54316.1| putative TetR family transcriptional regulator [Rhodococcus opacus B4] Length=212 Score = 85.1 bits (209), Expect = 6e-15, Method: Compositional matrix adjust. Identities = 49/181 (28%), Positives = 95/181 (53%), Gaps = 12/181 (6%) Query 5 RRRLSPQDRRAELLALGAEVFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFFAAVV 64 R RLSP+ RRA+L+ LGA++ +RP +++ +++IA++AGVSR L++HYF K F +V Sbjct 6 RTRLSPEQRRAQLIDLGAKMLAERPLEQISVEDIADQAGVSRGLLFHYFASKHDFHLEIV 65 Query 65 KDEADRLYAATNKAPAPGMTM--FEEIRTGVLAYMAYHQQNPEAAWAAYVGLGRSDPVLL 122 + + + A T P G + + +R+ + +Y+ Y +N + G DP + Sbjct 66 RHTSSEMLARTAPDPYVGESRDPMQILRSVLASYVDYVTENRGTYVSLLRGTASGDPDMR 125 Query 123 GIDDEAKNRQMEHIMSRIAEVVSGIDRDNTLDPEVERDLRVIIHGWLAFTFELCRQRIMD 182 + ++ + E + ++ + GI+ +D + + GW+A+ E+ + D Sbjct 126 AVFEQTRAVMSERTLEQLPAI--GIEPTRAVD--------LAVRGWIAYVEEVTITWLRD 175 Query 183 P 183 P Sbjct 176 P 176 >gi|312138898|ref|YP_004006234.1| tetr family transcriptional regulator [Rhodococcus equi 103S] gi|311888237|emb|CBH47549.1| putative TetR family transcriptional regulator [Rhodococcus equi 103S] Length=203 Score = 85.1 bits (209), Expect = 7e-15, Method: Compositional matrix adjust. Identities = 53/197 (27%), Positives = 98/197 (50%), Gaps = 12/197 (6%) Query 2 ATARRRLSPQDRRAELLALGAEVFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFFA 61 A R RLSP++RRA+L+ LG + RP +++ +++IA++AGVSR L++HYF K F Sbjct 3 AVKRVRLSPEERRAQLIDLGVRMLADRPLEQISVEDIADQAGVSRGLLFHYFASKHDFHV 62 Query 62 AVVKDEADRLYAATNKAPAPGMTMFEEIRTGVLAYMAYHQQNPEAAWAAYVGLGRSDPVL 121 A+V+ + + A T AP + + + +R + AY+ Y +N + + G DP + Sbjct 63 AIVRHSSAEMLART--APNLELPVIDMLRDVMAAYVDYVSENRDTYVSLLRGTASGDPAM 120 Query 122 LGIDDEAKNRQMEHIMSRIAEVVSGIDRDNTLDPEVERDLRVIIHGWLAFTFELCRQRIM 181 + + + ++ ++ + GI+ D + + + GW+AF E + Sbjct 121 REVFESTRAEMARRVVEQLPSL--GIEPDAR--------IALSVRGWIAFVEEATITWLR 170 Query 182 DPSTDAERLADACAHAL 198 P + L + AL Sbjct 171 GPEIPRDELIELLVTAL 187 >gi|325676395|ref|ZP_08156073.1| TetR family transcriptional regulator [Rhodococcus equi ATCC 33707] gi|325552573|gb|EGD22257.1| TetR family transcriptional regulator [Rhodococcus equi ATCC 33707] Length=203 Score = 85.1 bits (209), Expect = 7e-15, Method: Compositional matrix adjust. Identities = 53/197 (27%), Positives = 98/197 (50%), Gaps = 12/197 (6%) Query 2 ATARRRLSPQDRRAELLALGAEVFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFFA 61 A R RLSP++RRA+L+ LG + RP +++ +++IA++AGVSR L++HYF K F Sbjct 3 AVKRVRLSPEERRAQLIDLGVRMLADRPLEQISVEDIADQAGVSRGLLFHYFASKHDFHV 62 Query 62 AVVKDEADRLYAATNKAPAPGMTMFEEIRTGVLAYMAYHQQNPEAAWAAYVGLGRSDPVL 121 A+V+ + + A T AP + + + +R + AY+ Y +N + + G DP + Sbjct 63 AIVRHSSAEMLART--APNLELPVIDMLRDVMAAYVDYVSENRDTYVSLLRGTASGDPAM 120 Query 122 LGIDDEAKNRQMEHIMSRIAEVVSGIDRDNTLDPEVERDLRVIIHGWLAFTFELCRQRIM 181 + + + ++ ++ + GI+ D + + + GW+AF E + Sbjct 121 REVFESTRAEMARRVVEQLPSL--GIEPDAR--------IALSVRGWIAFVEEATITWLR 170 Query 182 DPSTDAERLADACAHAL 198 P + L + AL Sbjct 171 GPEIPRDELIELLVTAL 187 >gi|262201822|ref|YP_003273030.1| TetR family transcriptional regulator [Gordonia bronchialis DSM 43247] gi|262085169|gb|ACY21137.1| regulatory protein TetR [Gordonia bronchialis DSM 43247] Length=204 Score = 84.0 bits (206), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 52/182 (29%), Positives = 95/182 (53%), Gaps = 17/182 (9%) Query 5 RRRLSPQDRRAELLALGAEVFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFFAAVV 64 R R+SP+ RR +L+ G E+ +RP ++V I+ IAE AGVSRAL++HYF K+ F A+ Sbjct 8 RTRMSPEARRDQLIEYGLEMVAQRPLEQVSIEAIAEAAGVSRALLFHYFESKQDFHVAIA 67 Query 65 KDEADRLYAATNKAPAPGMTMFEE---IRTGVLAYMAYHQQNPEAAWAAYVGLGRSDPVL 121 + +++R+ A T AP ++ + +++ + A++ Y N A G DP + Sbjct 68 QTQSERMLACT----APDESLGDPLAILQSSMSAFVDYVSVNRSAYMTLIRGASSVDPAM 123 Query 122 LGIDDEAKNRQMEHIMSRIAEVVSGIDRDNTLDPEVERDLRVIIHGWLAFTFELCRQRIM 181 + D ++ + ++ + + GI + P +E + + GW++F E + Sbjct 124 RAVFDSTRSVMAQRVLDHLPAL--GI----AVTPTIE----ITVRGWMSFVEETTIGWLE 173 Query 182 DP 183 DP Sbjct 174 DP 175 >gi|326382055|ref|ZP_08203748.1| regulatory protein TetR [Gordonia neofelifaecis NRRL B-59395] gi|326199481|gb|EGD56662.1| regulatory protein TetR [Gordonia neofelifaecis NRRL B-59395] Length=201 Score = 83.6 bits (205), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 62/198 (32%), Positives = 97/198 (49%), Gaps = 11/198 (5%) Query 1 MATARRRLSPQDRRAELLALGAEVFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFF 60 M +AR RLSP RR +L+ LG E+ RP + V ++ +AE AGVS+ L++HYF K F Sbjct 1 MTSARTRLSPAARRRQLIDLGVELARDRPLELVTMEAVAEAAGVSKGLIFHYFESKADFH 60 Query 61 AAVVKDEADRLYAATNKAPAPGMTMFEEIRTGVLAYMAYHQQNPEAAWAAYVGLGRSDPV 120 V+ ++A+ + A T G T+ E ++ + AY+ Y N G +D Sbjct 61 LCVITEQAEEMLARTAPRDDIGDTI-EMLQASITAYVDYVADNGRGFVGVIRGAASADAA 119 Query 121 LLGIDDEAKNRQMEHIMSRIAEVVSGIDRDNTLDPEVERDLRVIIHGWLAFTFELCRQRI 180 + + D + E I+SR + GI+R P +E + + GW+AF E + I Sbjct 120 IRAVADRTRAAMTERILSRAPSI--GIER----TPAIE----LAVAGWIAFVEESLVRWI 169 Query 181 MDPSTDAERLADACAHAL 198 DP ++L AL Sbjct 170 DDPVVTRDQLVQIFVGAL 187 >gi|326771651|ref|ZP_08230936.1| TetR family transcriptional regulator [Actinomyces viscosus C505] gi|326637784|gb|EGE38685.1| TetR family transcriptional regulator [Actinomyces viscosus C505] Length=331 Score = 81.6 bits (200), Expect = 7e-14, Method: Compositional matrix adjust. Identities = 60/203 (30%), Positives = 92/203 (46%), Gaps = 18/203 (8%) Query 5 RRRLSPQDRRAELLALGAEVFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFFAAVV 64 RRRL P+ RR EL+ +G E+F + D ++EI +RAGVSR L YHYFP K AF A+V Sbjct 125 RRRLQPEQRREELVRVGVELFAEGTLDRTHVNEIIKRAGVSRTLFYHYFPSKMAFARAIV 184 Query 65 KDEADRLYAATNKAPAPGMTMFEEIRTGVLAYMAYHQQNPEAAWAAYVGLGRSDPVLLGI 124 + E L+ + A +T+ I T + Y + P++ A + G DP + Sbjct 185 EYEILHLHGLVEQQTA--LTLEGAIST----FAGYVKARPDSLRALHTGGLDQDPEIAAA 238 Query 125 DDEAKNRQMEHIMSRIAEVVSGIDRDNTLDPEVERDLRVIIHGWLAFTFELCRQRIMDPS 184 + R R+ ++ GI PE + H W++ LC + P Sbjct 239 LATSFER-----YERLVLMLMGI-------PEPDARAMFAAHVWISTMISLCLAWLDHPE 286 Query 185 TDAERLADACAHALLDAISRLPQ 207 E + + A L +S+ Q Sbjct 287 ISQETITNMSAQTLRSLVSQARQ 309 Lambda K H 0.322 0.135 0.394 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 276581767512 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40