BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv3297 Length=255 Score E Sequences producing significant alignments: (Bits) Value gi|15610433|ref|NP_217814.1| endonuclease VIII [Mycobacterium tu... 513 1e-143 gi|340628279|ref|YP_004746731.1| putative endonuclease VIII NEI ... 511 3e-143 gi|344221133|gb|AEN01764.1| endonuclease VIII [Mycobacterium tub... 510 6e-143 gi|254552399|ref|ZP_05142846.1| endonuclease VIII nei [Mycobacte... 508 2e-142 gi|254776704|ref|ZP_05218220.1| hypothetical protein MaviaA2_188... 406 1e-111 gi|254820684|ref|ZP_05225685.1| hypothetical protein MintA_12186... 400 1e-109 gi|118618117|ref|YP_906449.1| endonuclease VIII Nei [Mycobacteri... 396 2e-108 gi|183981259|ref|YP_001849550.1| endonuclease VIII Nei [Mycobact... 395 4e-108 gi|296168906|ref|ZP_06850575.1| endonuclease VIII [Mycobacterium... 394 9e-108 gi|41409514|ref|NP_962350.1| hypothetical protein MAP3416 [Mycob... 393 2e-107 gi|342861511|ref|ZP_08718158.1| hypothetical protein MCOL_21601 ... 385 3e-105 gi|240173489|ref|ZP_04752147.1| endonuclease VIII Nei [Mycobacte... 382 4e-104 gi|108798236|ref|YP_638433.1| DNA-formamidopyrimidine glycosylas... 356 2e-96 gi|333991756|ref|YP_004524370.1| endonuclease VIII Nei [Mycobact... 356 2e-96 gi|118472403|ref|YP_886128.1| endonuclease VIII and DNA n-glycos... 353 1e-95 gi|126433893|ref|YP_001069584.1| DNA-formamidopyrimidine glycosy... 353 2e-95 gi|145225389|ref|YP_001136067.1| formamidopyrimidine-DNA glycosy... 322 5e-86 gi|120402637|ref|YP_952466.1| DNA-formamidopyrimidine glycosylas... 321 8e-86 gi|315445737|ref|YP_004078616.1| formamidopyrimidine-DNA glycosy... 319 2e-85 gi|296394819|ref|YP_003659703.1| DNA glycosylase/AP lyase, H2TH ... 296 1e-78 gi|289755420|ref|ZP_06514798.1| endonuclease VIII nei [Mycobacte... 296 2e-78 gi|169631801|ref|YP_001705450.1| putative DNA glycosylase Nei [M... 284 9e-75 gi|312140746|ref|YP_004008082.1| DNA-formamidopyrimidine glycosy... 261 6e-68 gi|119716555|ref|YP_923520.1| formamidopyrimidine-DNA glycolase ... 249 3e-64 gi|229489614|ref|ZP_04383477.1| endonuclease VIII and DNA n-glyc... 245 5e-63 gi|226305585|ref|YP_002765545.1| DNA glycosylase [Rhodococcus er... 244 1e-62 gi|311743597|ref|ZP_07717403.1| endonuclease VIII [Aeromicrobium... 242 4e-62 gi|345009750|ref|YP_004812104.1| H2TH DNA-binding DNA glycosylas... 238 7e-61 gi|111023233|ref|YP_706205.1| DNA-formamidopyrimidine glycosylas... 237 1e-60 gi|50955599|ref|YP_062887.1| DNA glycosylase [Leifsonia xyli sub... 237 1e-60 gi|297156756|gb|ADI06468.1| endonuclease VIII and DNA N-glycosyl... 236 2e-60 gi|148273833|ref|YP_001223394.1| putative endonuclease VIII/DNA ... 233 3e-59 gi|269127507|ref|YP_003300877.1| DNA-(apurinic or apyrimidinic s... 232 4e-59 gi|170780851|ref|YP_001709183.1| DNA glycosylase [Clavibacter mi... 231 8e-59 gi|302542087|ref|ZP_07294429.1| endonuclease VIII [Streptomyces ... 229 2e-58 gi|296138322|ref|YP_003645565.1| DNA glycosylase/AP lyase, H2TH ... 228 4e-58 gi|262201744|ref|YP_003272952.1| formamidopyrimidine-DNA glycosy... 228 7e-58 gi|226365740|ref|YP_002783523.1| DNA glycosylase [Rhodococcus op... 227 1e-57 gi|343926675|ref|ZP_08766173.1| putative DNA glycosylase [Gordon... 224 1e-56 gi|333921179|ref|YP_004494760.1| fomramidopyrimidine-DNA glycosy... 222 4e-56 gi|88854733|ref|ZP_01129399.1| DNA glycosylase [marine actinobac... 221 7e-56 gi|294815478|ref|ZP_06774121.1| DNA glycosylase [Streptomyces cl... 221 1e-55 gi|330466398|ref|YP_004404141.1| DNA-(apurinic or apyrimidinic s... 219 4e-55 gi|238063417|ref|ZP_04608126.1| formamidopyrimidine-DNA glycosyl... 218 5e-55 gi|326381980|ref|ZP_08203673.1| Formamidopyrimidine-DNA glycosyl... 218 9e-55 gi|302866006|ref|YP_003834643.1| DNA-(apurinic or apyrimidinic s... 218 1e-54 gi|297202801|ref|ZP_06920198.1| formamidopyrimidine-DNA glycosyl... 216 2e-54 gi|297191673|ref|ZP_06909071.1| DNA glycosylase [Streptomyces pr... 216 3e-54 gi|21224106|ref|NP_629885.1| DNA glycosylase [Streptomyces coeli... 214 7e-54 gi|289768704|ref|ZP_06528082.1| DNA glycosylase [Streptomyces li... 213 3e-53 >gi|15610433|ref|NP_217814.1| endonuclease VIII [Mycobacterium tuberculosis H37Rv] gi|15842888|ref|NP_337925.1| endonuclease VIII [Mycobacterium tuberculosis CDC1551] gi|31794477|ref|NP_856970.1| endonuclease VIII [Mycobacterium bovis AF2122/97] 76 more sequence titles Length=255 Score = 513 bits (1321), Expect = 1e-143, Method: Compositional matrix adjust. Identities = 255/255 (100%), Positives = 255/255 (100%), Gaps = 0/255 (0%) Query 1 MPEGDTVWHTAATLRRHLAGRTLTRCDIRVPRFAAVDLTGEVVDEVISRGKHLFIRTGTA 60 MPEGDTVWHTAATLRRHLAGRTLTRCDIRVPRFAAVDLTGEVVDEVISRGKHLFIRTGTA Sbjct 1 MPEGDTVWHTAATLRRHLAGRTLTRCDIRVPRFAAVDLTGEVVDEVISRGKHLFIRTGTA 60 Query 61 SIHSHLQMDGSWRVGNRPVRVDHRARIILEANQQEQAIRVVGVDLGLLEVIDRHNDGAVV 120 SIHSHLQMDGSWRVGNRPVRVDHRARIILEANQQEQAIRVVGVDLGLLEVIDRHNDGAVV Sbjct 61 SIHSHLQMDGSWRVGNRPVRVDHRARIILEANQQEQAIRVVGVDLGLLEVIDRHNDGAVV 120 Query 121 AHLGPDLLADDWDPQRAAANLIVAPDRPIAEALLDQRVLAGIGNVYCNELCFVSGVLPTA 180 AHLGPDLLADDWDPQRAAANLIVAPDRPIAEALLDQRVLAGIGNVYCNELCFVSGVLPTA Sbjct 121 AHLGPDLLADDWDPQRAAANLIVAPDRPIAEALLDQRVLAGIGNVYCNELCFVSGVLPTA 180 Query 181 PVSAVADPRRLVTRARDMLWVNRFRWNRCTTGDTRAGRRLWVYGRAGQGCRRCGTLIAYD 240 PVSAVADPRRLVTRARDMLWVNRFRWNRCTTGDTRAGRRLWVYGRAGQGCRRCGTLIAYD Sbjct 181 PVSAVADPRRLVTRARDMLWVNRFRWNRCTTGDTRAGRRLWVYGRAGQGCRRCGTLIAYD 240 Query 241 TTDERVRYWCPACQR 255 TTDERVRYWCPACQR Sbjct 241 TTDERVRYWCPACQR 255 >gi|340628279|ref|YP_004746731.1| putative endonuclease VIII NEI [Mycobacterium canettii CIPT 140010059] gi|340006469|emb|CCC45651.1| putative endonuclease VIII NEI [Mycobacterium canettii CIPT 140010059] Length=255 Score = 511 bits (1317), Expect = 3e-143, Method: Compositional matrix adjust. Identities = 254/255 (99%), Positives = 255/255 (100%), Gaps = 0/255 (0%) Query 1 MPEGDTVWHTAATLRRHLAGRTLTRCDIRVPRFAAVDLTGEVVDEVISRGKHLFIRTGTA 60 MPEGDTVWHTAATLRRHLAGRTLTRCDIRVPRFAAVDLTGEVVDEVISRGKHLFIRTGTA Sbjct 1 MPEGDTVWHTAATLRRHLAGRTLTRCDIRVPRFAAVDLTGEVVDEVISRGKHLFIRTGTA 60 Query 61 SIHSHLQMDGSWRVGNRPVRVDHRARIILEANQQEQAIRVVGVDLGLLEVIDRHNDGAVV 120 SIHSHLQM+GSWRVGNRPVRVDHRARIILEANQQEQAIRVVGVDLGLLEVIDRHNDGAVV Sbjct 61 SIHSHLQMNGSWRVGNRPVRVDHRARIILEANQQEQAIRVVGVDLGLLEVIDRHNDGAVV 120 Query 121 AHLGPDLLADDWDPQRAAANLIVAPDRPIAEALLDQRVLAGIGNVYCNELCFVSGVLPTA 180 AHLGPDLLADDWDPQRAAANLIVAPDRPIAEALLDQRVLAGIGNVYCNELCFVSGVLPTA Sbjct 121 AHLGPDLLADDWDPQRAAANLIVAPDRPIAEALLDQRVLAGIGNVYCNELCFVSGVLPTA 180 Query 181 PVSAVADPRRLVTRARDMLWVNRFRWNRCTTGDTRAGRRLWVYGRAGQGCRRCGTLIAYD 240 PVSAVADPRRLVTRARDMLWVNRFRWNRCTTGDTRAGRRLWVYGRAGQGCRRCGTLIAYD Sbjct 181 PVSAVADPRRLVTRARDMLWVNRFRWNRCTTGDTRAGRRLWVYGRAGQGCRRCGTLIAYD 240 Query 241 TTDERVRYWCPACQR 255 TTDERVRYWCPACQR Sbjct 241 TTDERVRYWCPACQR 255 >gi|344221133|gb|AEN01764.1| endonuclease VIII [Mycobacterium tuberculosis CTRI-2] Length=255 Score = 510 bits (1314), Expect = 6e-143, Method: Compositional matrix adjust. Identities = 254/255 (99%), Positives = 254/255 (99%), Gaps = 0/255 (0%) Query 1 MPEGDTVWHTAATLRRHLAGRTLTRCDIRVPRFAAVDLTGEVVDEVISRGKHLFIRTGTA 60 MPEGDTVWHTAATLRRHLAGRTLTRCDIRVPRFAAVDLTGEVVDEVISRGKHLFIRTGTA Sbjct 1 MPEGDTVWHTAATLRRHLAGRTLTRCDIRVPRFAAVDLTGEVVDEVISRGKHLFIRTGTA 60 Query 61 SIHSHLQMDGSWRVGNRPVRVDHRARIILEANQQEQAIRVVGVDLGLLEVIDRHNDGAVV 120 SIHSHLQMDGSWRVGNRPVRVDHRARIILEANQQEQAIRVVGVDLGLLEVIDRHNDGAVV Sbjct 61 SIHSHLQMDGSWRVGNRPVRVDHRARIILEANQQEQAIRVVGVDLGLLEVIDRHNDGAVV 120 Query 121 AHLGPDLLADDWDPQRAAANLIVAPDRPIAEALLDQRVLAGIGNVYCNELCFVSGVLPTA 180 AHLGPDLLADDWDPQRAAANLIVAPDRPIAEALLDQRVLAGIGNVYCNELCFVSGVLPTA Sbjct 121 AHLGPDLLADDWDPQRAAANLIVAPDRPIAEALLDQRVLAGIGNVYCNELCFVSGVLPTA 180 Query 181 PVSAVADPRRLVTRARDMLWVNRFRWNRCTTGDTRAGRRLWVYGRAGQGCRRCGTLIAYD 240 PVSAVADPRRLVTRARDMLWVNRFRWNRCTTGDTRAGRRLWVYGRAGQGCRRCG LIAYD Sbjct 181 PVSAVADPRRLVTRARDMLWVNRFRWNRCTTGDTRAGRRLWVYGRAGQGCRRCGMLIAYD 240 Query 241 TTDERVRYWCPACQR 255 TTDERVRYWCPACQR Sbjct 241 TTDERVRYWCPACQR 255 >gi|254552399|ref|ZP_05142846.1| endonuclease VIII nei [Mycobacterium tuberculosis '98-R604 INH-RIF-EM'] Length=255 Score = 508 bits (1309), Expect = 2e-142, Method: Compositional matrix adjust. Identities = 254/255 (99%), Positives = 254/255 (99%), Gaps = 0/255 (0%) Query 1 MPEGDTVWHTAATLRRHLAGRTLTRCDIRVPRFAAVDLTGEVVDEVISRGKHLFIRTGTA 60 MPEGDTVWHTAATLRRHLAGRTLTRCDIRVPRFAAVDLTGEVVDEVISRGKHLFIRTGTA Sbjct 1 MPEGDTVWHTAATLRRHLAGRTLTRCDIRVPRFAAVDLTGEVVDEVISRGKHLFIRTGTA 60 Query 61 SIHSHLQMDGSWRVGNRPVRVDHRARIILEANQQEQAIRVVGVDLGLLEVIDRHNDGAVV 120 SIHSHLQMDGSWRVGNRPVRVDHRARIILEANQQEQAIRVVGVDLGLLEVIDRHNDGAVV Sbjct 61 SIHSHLQMDGSWRVGNRPVRVDHRARIILEANQQEQAIRVVGVDLGLLEVIDRHNDGAVV 120 Query 121 AHLGPDLLADDWDPQRAAANLIVAPDRPIAEALLDQRVLAGIGNVYCNELCFVSGVLPTA 180 AHLGPDLLADDWDPQRAAANLIVAPDRPIAEALLDQRVLAGIGNVYCNELCFVSGVLPTA Sbjct 121 AHLGPDLLADDWDPQRAAANLIVAPDRPIAEALLDQRVLAGIGNVYCNELCFVSGVLPTA 180 Query 181 PVSAVADPRRLVTRARDMLWVNRFRWNRCTTGDTRAGRRLWVYGRAGQGCRRCGTLIAYD 240 PVSAVADPRRLVTRARDMLWVNRFR NRCTTGDTRAGRRLWVYGRAGQGCRRCGTLIAYD Sbjct 181 PVSAVADPRRLVTRARDMLWVNRFRCNRCTTGDTRAGRRLWVYGRAGQGCRRCGTLIAYD 240 Query 241 TTDERVRYWCPACQR 255 TTDERVRYWCPACQR Sbjct 241 TTDERVRYWCPACQR 255 >gi|254776704|ref|ZP_05218220.1| hypothetical protein MaviaA2_18836 [Mycobacterium avium subsp. avium ATCC 25291] Length=250 Score = 406 bits (1044), Expect = 1e-111, Method: Compositional matrix adjust. Identities = 200/255 (79%), Positives = 218/255 (86%), Gaps = 5/255 (1%) Query 1 MPEGDTVWHTAATLRRHLAGRTLTRCDIRVPRFAAVDLTGEVVDEVISRGKHLFIRTGTA 60 MPEGDTVWHTAA LR HL G TLTRCDIRVPRFA VDLTG+VVDE++SRGKHLFIR G A Sbjct 1 MPEGDTVWHTAAVLREHLLGETLTRCDIRVPRFATVDLTGQVVDEILSRGKHLFIRVGAA 60 Query 61 SIHSHLQMDGSWRVGNRPVRVDHRARIILEANQQEQAIRVVGVDLGLLEVIDRHNDGAVV 120 SIHSHL+M+GSWRVG R VRVDHRARI+LE VGVDLG+L ++DR DG V Sbjct 61 SIHSHLKMEGSWRVGPR-VRVDHRARIVLETGSAT----AVGVDLGVLRILDRDRDGEAV 115 Query 121 AHLGPDLLADDWDPQRAAANLIVAPDRPIAEALLDQRVLAGIGNVYCNELCFVSGVLPTA 180 AHLGPDLL +DWDP RAAANL+ P RPIAEALLDQRVLAGIGNVYCNELCFVSG LPTA Sbjct 116 AHLGPDLLGEDWDPARAAANLVARPQRPIAEALLDQRVLAGIGNVYCNELCFVSGQLPTA 175 Query 181 PVSAVADPRRLVTRARDMLWVNRFRWNRCTTGDTRAGRRLWVYGRAGQGCRRCGTLIAYD 240 PVSAVADPRRLV+RARDMLW+NRFRWNRCTTGDTR GR+LWVYGRAGQ CRRCGT I +D Sbjct 176 PVSAVADPRRLVSRARDMLWLNRFRWNRCTTGDTRNGRQLWVYGRAGQPCRRCGTPIEFD 235 Query 241 TTDERVRYWCPACQR 255 + +RV YWCP+CQR Sbjct 236 DSGDRVTYWCPSCQR 250 >gi|254820684|ref|ZP_05225685.1| hypothetical protein MintA_12186 [Mycobacterium intracellulare ATCC 13950] Length=251 Score = 400 bits (1028), Expect = 1e-109, Method: Compositional matrix adjust. Identities = 199/255 (79%), Positives = 218/255 (86%), Gaps = 4/255 (1%) Query 1 MPEGDTVWHTAATLRRHLAGRTLTRCDIRVPRFAAVDLTGEVVDEVISRGKHLFIRTGTA 60 MPEGDTVWHTAA LR HL G TLTRCD+RVPRFA VDLTGEVVDEV+SRGKHLFIR G A Sbjct 1 MPEGDTVWHTAAVLREHLVGATLTRCDVRVPRFATVDLTGEVVDEVVSRGKHLFIRVGRA 60 Query 61 SIHSHLQMDGSWRVGNRPVRVDHRARIILEANQQEQAIRVVGVDLGLLEVIDRHNDGAVV 120 SIHSHL+M+GSWRVG RPVRVDHRARI+LE +R VGVDLG+LE++DR DG V Sbjct 61 SIHSHLKMEGSWRVGERPVRVDHRARIVLETG----TVRAVGVDLGVLEILDRDRDGEAV 116 Query 121 AHLGPDLLADDWDPQRAAANLIVAPDRPIAEALLDQRVLAGIGNVYCNELCFVSGVLPTA 180 AHLGPDLL +DWD RAAANL+ P RPIAEALLDQR+LAGIGNVYCNELCFVSG LPTA Sbjct 117 AHLGPDLLGEDWDAARAAANLMADPHRPIAEALLDQRLLAGIGNVYCNELCFVSGHLPTA 176 Query 181 PVSAVADPRRLVTRARDMLWVNRFRWNRCTTGDTRAGRRLWVYGRAGQGCRRCGTLIAYD 240 PV A+ADP RLV+RAR+MLW+NRFRWNRCTTGDTR+GR+LWVYGRAGQ CRRC T I D Sbjct 177 PVGAIADPLRLVSRAREMLWLNRFRWNRCTTGDTRSGRQLWVYGRAGQRCRRCATPINVD 236 Query 241 TTDERVRYWCPACQR 255 T ERV YWCP+CQR Sbjct 237 DTKERVAYWCPSCQR 251 >gi|118618117|ref|YP_906449.1| endonuclease VIII Nei [Mycobacterium ulcerans Agy99] gi|118570227|gb|ABL04978.1| endonuclease VIII Nei [Mycobacterium ulcerans Agy99] Length=254 Score = 396 bits (1017), Expect = 2e-108, Method: Compositional matrix adjust. Identities = 202/258 (79%), Positives = 218/258 (85%), Gaps = 7/258 (2%) Query 1 MPEGDTVWHTAATLRRHLAGRTLTRCDIRVPRFAAVDLTGEVVDEVISRGKHLFIRTGTA 60 MPEGDTVWHTAA LR++LAG+TLTRCDIRVPRFA VDLTG+VV+EV SRGKHLFIRT Sbjct 1 MPEGDTVWHTAARLRQYLAGKTLTRCDIRVPRFATVDLTGQVVEEVQSRGKHLFIRTALV 60 Query 61 SIHSHLQMDGSWRVGNRPVRVDHRARIILEANQQEQAIRVVGVDLGLLEVIDRHNDGAVV 120 SIHSHL+MDGSWRVG+RP RVDH ARIILEAN IR VGVDLG+LE+++R N+GAVV Sbjct 61 SIHSHLKMDGSWRVGDRPPRVDHHARIILEAND----IRAVGVDLGVLELLERDNEGAVV 116 Query 121 AHLGPDLLADDWDPQRAAANLIVAPDRPIAEALLDQRVLAGIGNVYCNELCFVSGVLPTA 180 AHLGPDLL +DWDP AAANL P R IAEALLDQRVLAGIGNVYCNELCFVSG LPTA Sbjct 117 AHLGPDLLGEDWDPHIAAANLAADPHRCIAEALLDQRVLAGIGNVYCNELCFVSGHLPTA 176 Query 181 PVSAVADPRRLVTRARDMLWVNRFRWNRCTTGDTRAGRRLWVYGRAGQGCRRCGTLI--- 237 PVS VA P RLVTRAR+MLW NR RWNR TTGDTRAGR+LWVYGRAGQ CRRC T I Sbjct 177 PVSDVAKPLRLVTRAREMLWANRLRWNRTTTGDTRAGRQLWVYGRAGQPCRRCATGIERQ 236 Query 238 AYDTTDERVRYWCPACQR 255 D + ERVRYWCPACQR Sbjct 237 GPDGSSERVRYWCPACQR 254 >gi|183981259|ref|YP_001849550.1| endonuclease VIII Nei [Mycobacterium marinum M] gi|183174585|gb|ACC39695.1| endonuclease VIII Nei [Mycobacterium marinum M] Length=254 Score = 395 bits (1014), Expect = 4e-108, Method: Compositional matrix adjust. Identities = 201/258 (78%), Positives = 218/258 (85%), Gaps = 7/258 (2%) Query 1 MPEGDTVWHTAATLRRHLAGRTLTRCDIRVPRFAAVDLTGEVVDEVISRGKHLFIRTGTA 60 MPEGDTVWHTAA LR++LAG+TLTRCDIRVPRFA VDLTG+VV++V SRGKHLFIRT Sbjct 1 MPEGDTVWHTAARLRQYLAGKTLTRCDIRVPRFATVDLTGQVVEQVQSRGKHLFIRTALV 60 Query 61 SIHSHLQMDGSWRVGNRPVRVDHRARIILEANQQEQAIRVVGVDLGLLEVIDRHNDGAVV 120 SIHSHL+MDGSWRVG+RP RVDH ARIILEAN IR VGVDLG+LE+++R N+GAVV Sbjct 61 SIHSHLKMDGSWRVGDRPPRVDHHARIILEAND----IRAVGVDLGVLELLERDNEGAVV 116 Query 121 AHLGPDLLADDWDPQRAAANLIVAPDRPIAEALLDQRVLAGIGNVYCNELCFVSGVLPTA 180 AHLGPDLL +DWDP AAANL P R IAEALLDQRVLAGIGNVYCNELCFVSG LPTA Sbjct 117 AHLGPDLLGEDWDPHIAAANLAADPHRCIAEALLDQRVLAGIGNVYCNELCFVSGHLPTA 176 Query 181 PVSAVADPRRLVTRARDMLWVNRFRWNRCTTGDTRAGRRLWVYGRAGQGCRRCGTLI--- 237 PVS VA P RLVTRAR+MLW NR RWNR TTGDTRAGR+LWVYGRAGQ CRRC T I Sbjct 177 PVSDVAKPLRLVTRAREMLWANRLRWNRTTTGDTRAGRQLWVYGRAGQPCRRCATGIERQ 236 Query 238 AYDTTDERVRYWCPACQR 255 D + ERVRYWCPACQR Sbjct 237 GPDGSSERVRYWCPACQR 254 >gi|296168906|ref|ZP_06850575.1| endonuclease VIII [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295896375|gb|EFG76028.1| endonuclease VIII [Mycobacterium parascrofulaceum ATCC BAA-614] Length=251 Score = 394 bits (1011), Expect = 9e-108, Method: Compositional matrix adjust. Identities = 198/255 (78%), Positives = 216/255 (85%), Gaps = 4/255 (1%) Query 1 MPEGDTVWHTAATLRRHLAGRTLTRCDIRVPRFAAVDLTGEVVDEVISRGKHLFIRTGTA 60 MPEGDTVWHTAA LR+HL GRTLTRCD+RVPR+A VDLTGE VDEV+SRGKHLFIR G A Sbjct 1 MPEGDTVWHTAALLRQHLVGRTLTRCDVRVPRYATVDLTGEAVDEVLSRGKHLFIRVGPA 60 Query 61 SIHSHLQMDGSWRVGNRPVRVDHRARIILEANQQEQAIRVVGVDLGLLEVIDRHNDGAVV 120 SIHSHL+MDGSWRVG RPVRVDHRARI+LEA +R VGVDLG+LE+++R D V Sbjct 61 SIHSHLKMDGSWRVGERPVRVDHRARIVLEAG----GVRAVGVDLGVLEILERDRDAEAV 116 Query 121 AHLGPDLLADDWDPQRAAANLIVAPDRPIAEALLDQRVLAGIGNVYCNELCFVSGVLPTA 180 AHLGPDLL +DWD AAANL PDRP+AE LLDQRVLAGIGNVY NELCFVSG LPTA Sbjct 117 AHLGPDLLGEDWDAGLAAANLAAHPDRPLAETLLDQRVLAGIGNVYANELCFVSGRLPTA 176 Query 181 PVSAVADPRRLVTRARDMLWVNRFRWNRCTTGDTRAGRRLWVYGRAGQGCRRCGTLIAYD 240 PVSAV DP RLV+RARDMLW+NRFRWNRCTTGDTR GR+LWVYGRAGQ CRRCGT I YD Sbjct 177 PVSAVGDPHRLVSRARDMLWLNRFRWNRCTTGDTRTGRQLWVYGRAGQRCRRCGTRIDYD 236 Query 241 TTDERVRYWCPACQR 255 + +RV YWCP CQR Sbjct 237 GSGDRVTYWCPPCQR 251 >gi|41409514|ref|NP_962350.1| hypothetical protein MAP3416 [Mycobacterium avium subsp. paratuberculosis K-10] gi|41398345|gb|AAS05966.1| Nei [Mycobacterium avium subsp. paratuberculosis K-10] gi|336459619|gb|EGO38554.1| formamidopyrimidine-DNA glycosylase [Mycobacterium avium subsp. paratuberculosis S397] Length=250 Score = 393 bits (1009), Expect = 2e-107, Method: Compositional matrix adjust. Identities = 200/255 (79%), Positives = 218/255 (86%), Gaps = 5/255 (1%) Query 1 MPEGDTVWHTAATLRRHLAGRTLTRCDIRVPRFAAVDLTGEVVDEVISRGKHLFIRTGTA 60 MPEGDTVWHTAA LR HL G TLTRCDIRVPRFA VDLTG+VVDE++SRGKHLFIR G A Sbjct 1 MPEGDTVWHTAAVLREHLLGETLTRCDIRVPRFATVDLTGQVVDEILSRGKHLFIRVGAA 60 Query 61 SIHSHLQMDGSWRVGNRPVRVDHRARIILEANQQEQAIRVVGVDLGLLEVIDRHNDGAVV 120 SIHSHL+M+GSWRVG R VRVDHRARI+LE A VGVDLG+L+++DR DG V Sbjct 61 SIHSHLKMEGSWRVGPR-VRVDHRARIVLETG----AATAVGVDLGVLQILDRDRDGEAV 115 Query 121 AHLGPDLLADDWDPQRAAANLIVAPDRPIAEALLDQRVLAGIGNVYCNELCFVSGVLPTA 180 AHLGPDLL +DWDP RAAANL P RPIAEALLDQRVLAGIGNVYCNELCFVSG LPT Sbjct 116 AHLGPDLLGEDWDPARAAANLAARPQRPIAEALLDQRVLAGIGNVYCNELCFVSGHLPTT 175 Query 181 PVSAVADPRRLVTRARDMLWVNRFRWNRCTTGDTRAGRRLWVYGRAGQGCRRCGTLIAYD 240 PVSAVADPRRLV+RARDMLW+NRFRWNRCTTGDTR GR+LWVYGRAGQ CRRCGT I +D Sbjct 176 PVSAVADPRRLVSRARDMLWLNRFRWNRCTTGDTRNGRQLWVYGRAGQPCRRCGTPIEFD 235 Query 241 TTDERVRYWCPACQR 255 + +RV YWCP+CQR Sbjct 236 DSGDRVTYWCPSCQR 250 >gi|342861511|ref|ZP_08718158.1| hypothetical protein MCOL_21601 [Mycobacterium colombiense CECT 3035] gi|342131000|gb|EGT84289.1| hypothetical protein MCOL_21601 [Mycobacterium colombiense CECT 3035] Length=252 Score = 385 bits (989), Expect = 3e-105, Method: Compositional matrix adjust. Identities = 199/256 (78%), Positives = 220/256 (86%), Gaps = 5/256 (1%) Query 1 MPEGDTVWHTAATLRRHLAGRTLTRCDIRVPRFAAVDLTGEVVDEVISRGKHLFIRTGTA 60 MPEGDTVWHTAA LR HL G TLTRCDIRVPRFA VDLTG+VVDEV+SRGKHLF+R G A Sbjct 1 MPEGDTVWHTAAVLREHLVGATLTRCDIRVPRFATVDLTGQVVDEVLSRGKHLFVRVGAA 60 Query 61 SIHSHLQMDGSWRVGN-RPVRVDHRARIILEANQQEQAIRVVGVDLGLLEVIDRHNDGAV 119 SIHSHL+MDGSWRVGN RPVRVDHRARIILE + ++R VGVDLG+LEV++R DG Sbjct 61 SIHSHLKMDGSWRVGNNRPVRVDHRARIILETD----SVRAVGVDLGVLEVLERERDGDA 116 Query 120 VAHLGPDLLADDWDPQRAAANLIVAPDRPIAEALLDQRVLAGIGNVYCNELCFVSGVLPT 179 VAHLGPDLL +DWDP AAANL PDRPIAEALLDQRVLAG+GNVY NELCF+SG LPT Sbjct 117 VAHLGPDLLGEDWDPALAAANLAADPDRPIAEALLDQRVLAGVGNVYSNELCFLSGHLPT 176 Query 180 APVSAVADPRRLVTRARDMLWVNRFRWNRCTTGDTRAGRRLWVYGRAGQGCRRCGTLIAY 239 APV +ADP RLV+RARDMLW+NRFRWNRCTTGDTR GR+LWVYGR+GQ CRRCGT I + Sbjct 177 APVRDIADPHRLVSRARDMLWLNRFRWNRCTTGDTRNGRQLWVYGRSGQACRRCGTRINF 236 Query 240 DTTDERVRYWCPACQR 255 D + ERV YWCP+CQR Sbjct 237 DDSGERVTYWCPSCQR 252 >gi|240173489|ref|ZP_04752147.1| endonuclease VIII Nei [Mycobacterium kansasii ATCC 12478] Length=254 Score = 382 bits (980), Expect = 4e-104, Method: Compositional matrix adjust. Identities = 197/257 (77%), Positives = 214/257 (84%), Gaps = 7/257 (2%) Query 1 MPEGDTVWHTAATLRRHLAGRTLTRCDIRVPRFAAVDLTGEVVDEVISRGKHLFIRTGTA 60 MPEGDTVWHTA LR+ LAGRTLTRCDIRVPRFAAVDL+G +VDEV+SRGKHLFIR G Sbjct 1 MPEGDTVWHTAVVLRQQLAGRTLTRCDIRVPRFAAVDLSGHMVDEVLSRGKHLFIRVGGV 60 Query 61 SIHSHLQMDGSWRVGNRPVRVDHRARIILEANQQEQAIRVVGVDLGLLEVIDRHNDGAVV 120 SIHSHL+MDGSWRV VRVDHRARI+LEA+ IR VGVDLG+LE++D NDGAVV Sbjct 61 SIHSHLKMDGSWRVAEHSVRVDHRARIVLEADN----IRAVGVDLGVLELLDHDNDGAVV 116 Query 121 AHLGPDLLADDWDPQRAAANLIVAPDRPIAEALLDQRVLAGIGNVYCNELCFVSGVLPTA 180 AHLGPDLL +DWD AAANL PDRPIAEALLDQRVLAGIGNVYCNELCFVSG LPTA Sbjct 117 AHLGPDLLGEDWDAAVAAANLAADPDRPIAEALLDQRVLAGIGNVYCNELCFVSGHLPTA 176 Query 181 PVSAVADPRRLVTRARDMLWVNRFRWNRCTTGDTRAGRRLWVYGRAGQGCRRCGTLIA-- 238 PVSA+ADP+RL TRAR MLW NRFRW+RCTTGDTRAGRRLWVYGRAG+ CRRCGT I Sbjct 177 PVSAIADPQRLATRARTMLWANRFRWSRCTTGDTRAGRRLWVYGRAGEPCRRCGTCIECL 236 Query 239 -YDTTDERVRYWCPACQ 254 RV++WCP CQ Sbjct 237 HAGAGAGRVQFWCPTCQ 253 >gi|108798236|ref|YP_638433.1| DNA-formamidopyrimidine glycosylase [Mycobacterium sp. MCS] gi|119867332|ref|YP_937284.1| DNA-formamidopyrimidine glycosylase [Mycobacterium sp. KMS] gi|108768655|gb|ABG07377.1| DNA-formamidopyrimidine glycosylase [Mycobacterium sp. MCS] gi|119693421|gb|ABL90494.1| DNA-formamidopyrimidine glycosylase [Mycobacterium sp. KMS] Length=257 Score = 356 bits (914), Expect = 2e-96, Method: Compositional matrix adjust. Identities = 173/257 (68%), Positives = 205/257 (80%), Gaps = 2/257 (0%) Query 1 MPEGDTVWHTAATLRRHLAGRTLTRCDIRVPRFAAVDLTGEVVDEVISRGKHLFIRTGTA 60 MPEGDTV+ TA LR L G+TLTRCD+RVPR+A VDLTG VVDEV+SRGKHLFIR G A Sbjct 1 MPEGDTVYRTATALREGLVGKTLTRCDVRVPRYATVDLTGHVVDEVLSRGKHLFIRVGPA 60 Query 61 SIHSHLQMDGSWRV--GNRPVRVDHRARIILEANQQEQAIRVVGVDLGLLEVIDRHNDGA 118 SIHSHL+M+GSW+V +RP R +R RIILEA + EQA++ G+DLG+LE+++R +D Sbjct 61 SIHSHLKMEGSWKVVPASRPSRAGYRIRIILEAGEGEQAVQAAGIDLGVLEILERDHDME 120 Query 119 VVAHLGPDLLADDWDPQRAAANLIVAPDRPIAEALLDQRVLAGIGNVYCNELCFVSGVLP 178 VAHLGPDLL DDW+P+ AA NL PDR ++EALLDQRV+AG+GNVY NELCFV+G LP Sbjct 121 TVAHLGPDLLGDDWEPRVAARNLSADPDRRLSEALLDQRVMAGVGNVYANELCFVAGHLP 180 Query 179 TAPVSAVADPRRLVTRARDMLWVNRFRWNRCTTGDTRAGRRLWVYGRAGQGCRRCGTLIA 238 TAPV + DP R+V RARDMLW+NR RWNR TTGDTR GR +WVYGRAG+ CRRCGT I Sbjct 181 TAPVRDLKDPLRMVHRARDMLWLNRSRWNRTTTGDTRPGRDVWVYGRAGKPCRRCGTPIR 240 Query 239 YDTTDERVRYWCPACQR 255 D +RV YWCP CQR Sbjct 241 RDGNGDRVSYWCPHCQR 257 >gi|333991756|ref|YP_004524370.1| endonuclease VIII Nei [Mycobacterium sp. JDM601] gi|333487724|gb|AEF37116.1| endonuclease VIII Nei [Mycobacterium sp. JDM601] Length=253 Score = 356 bits (913), Expect = 2e-96, Method: Compositional matrix adjust. Identities = 183/258 (71%), Positives = 208/258 (81%), Gaps = 8/258 (3%) Query 1 MPEGDTVWHTAATLRRHLAGRTLTRCDIRVPRFAAVDLTGEVVDEVISRGKHLFIRTGTA 60 MPEGDTV+HTAA L L G+TLTRCDIRVPR+A VDLTG+ VDEVISRGKHLFIR G A Sbjct 1 MPEGDTVFHTAAVLDDALTGKTLTRCDIRVPRYAGVDLTGQRVDEVISRGKHLFIRVGQA 60 Query 61 SIHSHLQMDGSWRVGNRPVR---VDHRARIILEANQQEQAIRVVGVDLGLLEVIDRHNDG 117 SIHSHL+M+GSWRVG+ P R +DHR RIILEA +R +G+DLG+LEV++RH DG Sbjct 61 SIHSHLKMEGSWRVGS-PARRDPLDHRVRIILEAG----PVRALGIDLGVLEVLERHRDG 115 Query 118 AVVAHLGPDLLADDWDPQRAAANLIVAPDRPIAEALLDQRVLAGIGNVYCNELCFVSGVL 177 VAHLGPDLL DWDP A ANL+ PDRP+A ALLDQRVLAGIGNVYCNELCFV G L Sbjct 116 EAVAHLGPDLLGPDWDPAAALANLLADPDRPLAAALLDQRVLAGIGNVYCNELCFVVGRL 175 Query 178 PTAPVSAVADPRRLVTRARDMLWVNRFRWNRCTTGDTRAGRRLWVYGRAGQGCRRCGTLI 237 PT+PV+A+ADP RLV RAR+MLW NR RW RCTTGDTR GR+LWVYGRAG+ CRRCGT + Sbjct 176 PTSPVAALADPARLVARAREMLWANRLRWARCTTGDTRPGRQLWVYGRAGKPCRRCGTRV 235 Query 238 AYDTTDERVRYWCPACQR 255 D+ RV +WC ACQR Sbjct 236 ESDSGGGRVSFWCAACQR 253 >gi|118472403|ref|YP_886128.1| endonuclease VIII and DNA n-glycosylase with an AP lyase activity [Mycobacterium smegmatis str. MC2 155] gi|118173690|gb|ABK74586.1| endonuclease VIII and dna n-glycosylase with an ap lyase activity [Mycobacterium smegmatis str. MC2 155] Length=252 Score = 353 bits (906), Expect = 1e-95, Method: Compositional matrix adjust. Identities = 173/254 (69%), Positives = 202/254 (80%), Gaps = 5/254 (1%) Query 1 MPEGDTVWHTAATLRRHLAGRTLTRCDIRVPRFAAVDLTGEVVDEVISRGKHLFIRTGTA 60 MPEGDTV+HTAA LR L G+TLTRCD+RVPR+A VDL+G VVDEV+SRGKHLFIR G+A Sbjct 1 MPEGDTVFHTAAALRAALEGKTLTRCDVRVPRYATVDLSGAVVDEVLSRGKHLFIRAGSA 60 Query 61 SIHSHLQMDGSWRVGNRPVRVDHRARIILEANQQEQAIRVVGVDLGLLEVIDRHNDGAVV 120 SIHSHL+M+G+WR+G+ V HR RI+LE R +G+DLG+LEV+DR D V Sbjct 61 SIHSHLKMEGAWRIGHTKV-APHRIRIVLETAD----TRAIGIDLGILEVLDRGTDMDAV 115 Query 121 AHLGPDLLADDWDPQRAAANLIVAPDRPIAEALLDQRVLAGIGNVYCNELCFVSGVLPTA 180 A+LGPDLL DW+P+ AA NL PDRP+A+ALLDQRV+AG+GNVYCNELCFV G LPTA Sbjct 116 AYLGPDLLGPDWEPRVAADNLAADPDRPLAQALLDQRVMAGVGNVYCNELCFVFGRLPTA 175 Query 181 PVSAVADPRRLVTRARDMLWVNRFRWNRCTTGDTRAGRRLWVYGRAGQGCRRCGTLIAYD 240 PV + DP R+V RARDMLW+NR RWNR TTGDTR GR+LWVYGRAG+ CRRCGTLI D Sbjct 176 PVGTLKDPLRVVQRARDMLWLNRSRWNRTTTGDTRNGRQLWVYGRAGEPCRRCGTLIQTD 235 Query 241 TTDERVRYWCPACQ 254 ERV YWCP CQ Sbjct 236 RGGERVTYWCPVCQ 249 >gi|126433893|ref|YP_001069584.1| DNA-formamidopyrimidine glycosylase [Mycobacterium sp. JLS] gi|126233693|gb|ABN97093.1| DNA-formamidopyrimidine glycosylase [Mycobacterium sp. JLS] Length=257 Score = 353 bits (906), Expect = 2e-95, Method: Compositional matrix adjust. Identities = 171/257 (67%), Positives = 203/257 (79%), Gaps = 2/257 (0%) Query 1 MPEGDTVWHTAATLRRHLAGRTLTRCDIRVPRFAAVDLTGEVVDEVISRGKHLFIRTGTA 60 MPEGDTV+ TA LR L G+TLTRCD+RVP +A VDLTG VVDEV+SRGKHLFIR G A Sbjct 1 MPEGDTVYRTATALREGLVGKTLTRCDVRVPHYATVDLTGHVVDEVLSRGKHLFIRVGPA 60 Query 61 SIHSHLQMDGSWRV--GNRPVRVDHRARIILEANQQEQAIRVVGVDLGLLEVIDRHNDGA 118 SIHSHL+M+GSW+V +RP R +R RIILEA + EQA++ G+DLG+LE+++R +D Sbjct 61 SIHSHLKMEGSWKVVPASRPSRAGYRIRIILEAGEGEQAVQAAGIDLGVLEILERDHDME 120 Query 119 VVAHLGPDLLADDWDPQRAAANLIVAPDRPIAEALLDQRVLAGIGNVYCNELCFVSGVLP 178 VAHLGPDLL DDW+P+ AA NL PDR ++EALLDQRV+AG+GNVY NELCFV+G LP Sbjct 121 TVAHLGPDLLGDDWEPRVAARNLSADPDRRLSEALLDQRVMAGVGNVYANELCFVAGHLP 180 Query 179 TAPVSAVADPRRLVTRARDMLWVNRFRWNRCTTGDTRAGRRLWVYGRAGQGCRRCGTLIA 238 TAPV + DP R+V RARDMLW+NR RWNR TTGD R GR +WVYGRAG+ CRRCGT I Sbjct 181 TAPVRDLKDPLRMVQRARDMLWLNRSRWNRTTTGDARPGRDVWVYGRAGKPCRRCGTPIR 240 Query 239 YDTTDERVRYWCPACQR 255 D +RV YWCP CQR Sbjct 241 RDGNGDRVSYWCPHCQR 257 >gi|145225389|ref|YP_001136067.1| formamidopyrimidine-DNA glycosylase [Mycobacterium gilvum PYR-GCK] gi|145217875|gb|ABP47279.1| Formamidopyrimidine-DNA glycolase [Mycobacterium gilvum PYR-GCK] Length=250 Score = 322 bits (824), Expect = 5e-86, Method: Compositional matrix adjust. Identities = 161/256 (63%), Positives = 190/256 (75%), Gaps = 7/256 (2%) Query 1 MPEGDTVWHTAATLRRHLAGRTLTRCDIRVPRFAAVDLTGEVVDEVISRGKHLFIRTGTA 60 MPEGDTV+ TAA LR L GR LTRCDIRVPR+AAVDL+G+VVDEV+SRGKHLFIR G A Sbjct 1 MPEGDTVYRTAAKLRDALEGRELTRCDIRVPRYAAVDLSGQVVDEVLSRGKHLFIRVGQA 60 Query 61 SIHSHLQMDGSWRVGNRPVRV-DHRARIILEANQQEQAIRVVGVDLGLLEVIDRHNDGAV 119 SIHSHL+MDG+W +G VRV ++ RI+LE R GVDLG+LEV+DR D Sbjct 61 SIHSHLKMDGAWVIGR--VRVPTYKIRIVLETANS----RASGVDLGVLEVLDRATDMEA 114 Query 120 VAHLGPDLLADDWDPQRAAANLIVAPDRPIAEALLDQRVLAGIGNVYCNELCFVSGVLPT 179 V HLGPDLL +DW + AAANL+ P+RP+AE LLDQRV+AG+GNV+ NEL FV G+ P Sbjct 115 VEHLGPDLLGEDWSAEVAAANLVADPERPLAETLLDQRVMAGVGNVFANELSFVFGLRPG 174 Query 180 APVSAVADPRRLVTRARDMLWVNRFRWNRCTTGDTRAGRRLWVYGRAGQGCRRCGTLIAY 239 PV + DP R+ RA+ MLW+NR R NR TTG+TR G+ +WVYGRAG CRRCGT I Sbjct 175 TPVGELTDPLRVANRAQQMLWLNRLRVNRTTTGNTRPGQDVWVYGRAGLPCRRCGTPIET 234 Query 240 DTTDERVRYWCPACQR 255 D ERV YWCP CQR Sbjct 235 DKNTERVTYWCPTCQR 250 >gi|120402637|ref|YP_952466.1| DNA-formamidopyrimidine glycosylase [Mycobacterium vanbaalenii PYR-1] gi|119955455|gb|ABM12460.1| DNA-formamidopyrimidine glycosylase [Mycobacterium vanbaalenii PYR-1] Length=250 Score = 321 bits (822), Expect = 8e-86, Method: Compositional matrix adjust. Identities = 161/256 (63%), Positives = 191/256 (75%), Gaps = 7/256 (2%) Query 1 MPEGDTVWHTAATLRRHLAGRTLTRCDIRVPRFAAVDLTGEVVDEVISRGKHLFIRTGTA 60 MPEGDTV+ TAA LR L GR LTRCD+RVPR+AAVDL+G+ VDEV+SRGKHLFIR G A Sbjct 1 MPEGDTVYRTAAKLREALEGRELTRCDVRVPRYAAVDLSGQTVDEVLSRGKHLFIRVGQA 60 Query 61 SIHSHLQMDGSWRVGNRPVRV-DHRARIILEANQQEQAIRVVGVDLGLLEVIDRHNDGAV 119 SIHSHL+MDG+W +G VRV ++ RI+LE + R GVDLG+LE++DR D Sbjct 61 SIHSHLKMDGAWVIGR--VRVPSYKIRIVLETARS----RASGVDLGVLEILDRATDMEA 114 Query 120 VAHLGPDLLADDWDPQRAAANLIVAPDRPIAEALLDQRVLAGIGNVYCNELCFVSGVLPT 179 VAHLGPDLL DW AAANL+ P RP+AEALLDQRV+AG+GNVY NELCFV G+ P Sbjct 115 VAHLGPDLLGPDWSAPLAAANLVADPSRPVAEALLDQRVMAGVGNVYANELCFVFGLRPG 174 Query 180 APVSAVADPRRLVTRARDMLWVNRFRWNRCTTGDTRAGRRLWVYGRAGQGCRRCGTLIAY 239 V +ADP R+ +RA+ MLW+NR R NR TTG+TR G+ +WVYGRAG CRRCGT I Sbjct 175 TAVGELADPVRVASRAQQMLWLNRLRVNRTTTGNTRPGQDVWVYGRAGLPCRRCGTPIET 234 Query 240 DTTDERVRYWCPACQR 255 D +RV YWCP CQR Sbjct 235 DKGGDRVTYWCPTCQR 250 >gi|315445737|ref|YP_004078616.1| formamidopyrimidine-DNA glycosylase [Mycobacterium sp. Spyr1] gi|315264040|gb|ADU00782.1| formamidopyrimidine-DNA glycosylase [Mycobacterium sp. Spyr1] Length=250 Score = 319 bits (818), Expect = 2e-85, Method: Compositional matrix adjust. Identities = 160/256 (63%), Positives = 189/256 (74%), Gaps = 7/256 (2%) Query 1 MPEGDTVWHTAATLRRHLAGRTLTRCDIRVPRFAAVDLTGEVVDEVISRGKHLFIRTGTA 60 MPEGDTV+ TAA LR L GR L RCDIRVPR+AAVDL+G+VVDEV+SRGKHLFIR G A Sbjct 1 MPEGDTVYRTAAKLRDALEGRELIRCDIRVPRYAAVDLSGQVVDEVLSRGKHLFIRVGQA 60 Query 61 SIHSHLQMDGSWRVGNRPVRV-DHRARIILEANQQEQAIRVVGVDLGLLEVIDRHNDGAV 119 SIHSHL+MDG+W +G VRV ++ RI+LE R GVDLG+LEV+DR D Sbjct 61 SIHSHLKMDGAWVIGR--VRVPTYKIRIVLETANS----RASGVDLGVLEVLDRATDMEA 114 Query 120 VAHLGPDLLADDWDPQRAAANLIVAPDRPIAEALLDQRVLAGIGNVYCNELCFVSGVLPT 179 V HLGPDLL +DW + AAANL+ P+RP+AE LLDQRV+AG+GNV+ NEL FV G+ P Sbjct 115 VEHLGPDLLGEDWSAEVAAANLVADPERPLAETLLDQRVMAGVGNVFANELSFVFGLRPG 174 Query 180 APVSAVADPRRLVTRARDMLWVNRFRWNRCTTGDTRAGRRLWVYGRAGQGCRRCGTLIAY 239 PV + DP R+ RA+ MLW+NR R NR TTG+TR G+ +WVYGRAG CRRCGT I Sbjct 175 TPVGELTDPLRVANRAQQMLWLNRLRVNRTTTGNTRPGQDVWVYGRAGLPCRRCGTPIET 234 Query 240 DTTDERVRYWCPACQR 255 D ERV YWCP CQR Sbjct 235 DKNTERVTYWCPTCQR 250 >gi|296394819|ref|YP_003659703.1| DNA glycosylase/AP lyase, H2TH DNA-binding protein [Segniliparus rotundus DSM 44985] gi|296181966|gb|ADG98872.1| DNA glycosylase/AP lyase, H2TH DNA-binding protein [Segniliparus rotundus DSM 44985] Length=248 Score = 296 bits (759), Expect = 1e-78, Method: Compositional matrix adjust. Identities = 151/241 (63%), Positives = 176/241 (74%), Gaps = 9/241 (3%) Query 19 AGRTLTRCDIRVPRFAAVDLTGEVVDEVISRGKHLFIRTGTASIHSHLQMDGSWRVGNR- 77 +G+TL RCDIRVP++A VDL G VVDEV+SRGKHLFIR G AS+HSHL+M+G WRV + Sbjct 13 SGKTLVRCDIRVPKYATVDLAGHVVDEVLSRGKHLFIRIGPASVHSHLKMEGEWRVVAQK 72 Query 78 ---PVRVDHRARIILEANQQEQAIRVVGVDLGLLEVIDRHNDGAVVAHLGPDLLADDWDP 134 PVR D+R R +L A + +G+DLG+LEV+DR D A V+HLGPDLL DWDP Sbjct 73 PRTPVR-DYRVRAVLAAAD----VTALGLDLGVLEVLDRARDMAAVSHLGPDLLGPDWDP 127 Query 135 QRAAANLIVAPDRPIAEALLDQRVLAGIGNVYCNELCFVSGVLPTAPVSAVADPRRLVTR 194 + AA L PDRP+AE LLDQRV+AG+GNVYCNELCF+ G LPT+PV A DP RLV R Sbjct 128 ETAAERLTAQPDRPLAETLLDQRVMAGVGNVYCNELCFLVGRLPTSPVGAAGDPARLVAR 187 Query 195 ARDMLWVNRFRWNRCTTGDTRAGRRLWVYGRAGQGCRRCGTLIAYDTTDERVRYWCPACQ 254 A +L NR R R TTGD+R GR LWVYGR G CRRCGT I YD RVRYWCP CQ Sbjct 188 AHALLRANRDRARRTTTGDSRPGRELWVYGRRGLPCRRCGTPIRYDPDGPRVRYWCPFCQ 247 Query 255 R 255 R Sbjct 248 R 248 >gi|289755420|ref|ZP_06514798.1| endonuclease VIII nei [Mycobacterium tuberculosis EAS054] gi|289696007|gb|EFD63436.1| endonuclease VIII nei [Mycobacterium tuberculosis EAS054] Length=147 Score = 296 bits (759), Expect = 2e-78, Method: Compositional matrix adjust. Identities = 145/146 (99%), Positives = 146/146 (100%), Gaps = 0/146 (0%) Query 110 VIDRHNDGAVVAHLGPDLLADDWDPQRAAANLIVAPDRPIAEALLDQRVLAGIGNVYCNE 169 +IDRHNDGAVVAHLGPDLLADDWDPQRAAANLIVAPDRPIAEALLDQRVLAGIGNVYCNE Sbjct 2 LIDRHNDGAVVAHLGPDLLADDWDPQRAAANLIVAPDRPIAEALLDQRVLAGIGNVYCNE 61 Query 170 LCFVSGVLPTAPVSAVADPRRLVTRARDMLWVNRFRWNRCTTGDTRAGRRLWVYGRAGQG 229 LCFVSGVLPTAPVSAVADPRRLVTRARDMLWVNRFRWNRCTTGDTRAGRRLWVYGRAGQG Sbjct 62 LCFVSGVLPTAPVSAVADPRRLVTRARDMLWVNRFRWNRCTTGDTRAGRRLWVYGRAGQG 121 Query 230 CRRCGTLIAYDTTDERVRYWCPACQR 255 CRRCGTLIAYDTTDERVRYWCPACQR Sbjct 122 CRRCGTLIAYDTTDERVRYWCPACQR 147 >gi|169631801|ref|YP_001705450.1| putative DNA glycosylase Nei [Mycobacterium abscessus ATCC 19977] gi|169243768|emb|CAM64796.1| Putative DNA glycosylase Nei [Mycobacterium abscessus] Length=254 Score = 284 bits (727), Expect = 9e-75, Method: Compositional matrix adjust. Identities = 149/258 (58%), Positives = 176/258 (69%), Gaps = 7/258 (2%) Query 1 MPEGDTVWHTAATLRRHLAGRTLTRCDIRVPRFAAVDLTGEVVDEVISRGKHLFIRTGTA 60 MPEGDTV+ TA L L GR LT CDIRVPRFA VDL+G+ V+ VI+RGKHLFIR G A Sbjct 1 MPEGDTVFRTAKLLDDALGGRILTGCDIRVPRFATVDLSGQRVEGVIARGKHLFIRVGGA 60 Query 61 SIHSHLQMDGSWRV--GNRPVRV-DHRARIILEANQQEQAIRVVGVDLGLLEVIDRHNDG 117 SIHSHL+MDGSWR+ RP +HR R +L + VG LG+L+V+DR +G Sbjct 61 SIHSHLKMDGSWRIMPAGRPGPTWNHRIRAVLTTDDSV----AVGTSLGILDVVDRRREG 116 Query 118 AVVAHLGPDLLADDWDPQRAAANLIVAPDRPIAEALLDQRVLAGIGNVYCNELCFVSGVL 177 VV HLGPDLL DWDP A LI D ++ ALLDQRV+AGIGNVY NELCF++G+L Sbjct 117 DVVGHLGPDLLGTDWDPDVAVERLIARSDEALSAALLDQRVMAGIGNVYSNELCFLAGLL 176 Query 178 PTAPVSAVADPRRLVTRARDMLWVNRFRWNRCTTGDTRAGRRLWVYGRAGQGCRRCGTLI 237 PT V + DP LV RA ++ N+ + R TTGD R+GR LWVYGR G+ CRRCGT I Sbjct 177 PTTAVGRLGDPAGLVERAHTLMHANKDSYRRTTTGDPRSGRELWVYGRHGKPCRRCGTPI 236 Query 238 AYDTTDERVRYWCPACQR 255 A D RV YWCP CQR Sbjct 237 ARDQGLPRVAYWCPNCQR 254 >gi|312140746|ref|YP_004008082.1| DNA-formamidopyrimidine glycosylase [Rhodococcus equi 103S] gi|325675614|ref|ZP_08155298.1| endonuclease VIII [Rhodococcus equi ATCC 33707] gi|311890085|emb|CBH49403.1| DNA-formamidopyrimidine glycosylase [Rhodococcus equi 103S] gi|325553585|gb|EGD23263.1| endonuclease VIII [Rhodococcus equi ATCC 33707] Length=265 Score = 261 bits (668), Expect = 6e-68, Method: Compositional matrix adjust. Identities = 142/262 (55%), Positives = 172/262 (66%), Gaps = 12/262 (4%) Query 1 MPEGDTVWHTAATLRRHLAGRTLTRCDIRVPRFAAVDLTGEVVDEVISRGKHLFIRTGTA 60 MPEGDTVW A L LAGR LT CDIRVPR+A VDL+GE VD V++RGKHL R G Sbjct 1 MPEGDTVWQAARRLDTALAGRVLTECDIRVPRYATVDLSGEAVDAVVARGKHLLTRIGAH 60 Query 61 SIHSHLQMDGSWRV---GNRPVRVDHRARIILEANQQEQAIRVVGVDLGLLEVIDRHNDG 117 +IH+HL+M+GSW+V G R R H+ARI+L VG LG+ EV+DR ++ Sbjct 61 TIHTHLKMEGSWQVYPRGARWRRPAHQARIVLGTEDTV----AVGFSLGITEVVDRSDEE 116 Query 118 AVVAHLGPDLLADDWDPQRAAANLIVAPDRPIAEALLDQRVLAGIGNVYCNELCFVSGVL 177 +VV HLGPDLL DWD A +NL+ A +RPI EALLDQR++AGIGNVY NE+CF+ GV Sbjct 117 SVVGHLGPDLLGADWDAAVATSNLVAAGERPIGEALLDQRIMAGIGNVYRNEICFLRGVD 176 Query 178 PTAPVSAVADPRRLVTRARDMLWVNRFRWNRCTTGDTRAGRRLWVYGRAGQGCRRCGTLI 237 P P + V D ++V A +L NR R R TTGD R GRR WVYGR G+ C RCGT I Sbjct 177 PRTPTARVPDLPKVVDLAHRVLRANRDRPVRVTTGDRRPGRRDWVYGRGGKPCLRCGTPI 236 Query 238 A-----YDTTDERVRYWCPACQ 254 A + ER +WCP CQ Sbjct 237 AAAEFGEEPGRERSIFWCPNCQ 258 >gi|119716555|ref|YP_923520.1| formamidopyrimidine-DNA glycolase [Nocardioides sp. JS614] gi|119537216|gb|ABL81833.1| Formamidopyrimidine-DNA glycolase [Nocardioides sp. JS614] Length=268 Score = 249 bits (636), Expect = 3e-64, Method: Compositional matrix adjust. Identities = 134/269 (50%), Positives = 169/269 (63%), Gaps = 19/269 (7%) Query 1 MPEGDTVWHTAATLRRHLAGRTLTRCDIRVPRFAAVDLTGEVVDEVISRGKHLFIRTGTA 60 MPEGD VW TA LRR L G+ L R D+RVP+ A DL+G V E +SRGKHL R T Sbjct 1 MPEGDAVWRTAERLRRALDGQRLVRTDLRVPQHATTDLSGGTVLETVSRGKHLLTRINTH 60 Query 61 S--------IHSHLQMDGSWRV---GNRPVRVDHRARIILEANQQEQAIRVVGVDLGLLE 109 S +H+HL+M+GSWRV G R + H AR++L+ + VG LG+++ Sbjct 61 SDHGAEDWTLHTHLKMEGSWRVYRAGERWTKPAHLARVVLDVGGRS----AVGFQLGVVD 116 Query 110 VIDRHNDGAVVAHLGPDLLADDWDPQRAAANLIVAPDRPIAEALLDQRVLAGIGNVYCNE 169 ++ R + VV HLGPDLL DWD + A L P RP+ EALLDQR LAGIG +Y +E Sbjct 117 LLPREREDEVVGHLGPDLLGPDWDAEEAVRRLTADPTRPLGEALLDQRNLAGIGTIYRSE 176 Query 170 LCFVSGVLPTAPVSAVADPRRLVTRARDMLWVNRFRWNRCTTGDTRAGRRLWVYGRAGQG 229 LCF++G P P++ VADP R+V AR ML NR + CTTGD R GR LWVYGR+G+ Sbjct 177 LCFLTGYDPRDPLAVVADPLRMVRLARSMLDQNRHQAQICTTGDKRRGRSLWVYGRSGER 236 Query 230 CRRCGTLIAYDTTD----ERVRYWCPACQ 254 C RCGT I +D ER+ YWCP+CQ Sbjct 237 CLRCGTTIVHDQLGQPGRERIAYWCPSCQ 265 >gi|229489614|ref|ZP_04383477.1| endonuclease VIII and DNA n-glycosylase with an ap lyase activity [Rhodococcus erythropolis SK121] gi|229323711|gb|EEN89469.1| endonuclease VIII and DNA n-glycosylase with an ap lyase activity [Rhodococcus erythropolis SK121] Length=268 Score = 245 bits (625), Expect = 5e-63, Method: Compositional matrix adjust. Identities = 134/262 (52%), Positives = 166/262 (64%), Gaps = 12/262 (4%) Query 1 MPEGDTVWHTAATLRRHLAGRTLTRCDIRVPRFAAVDLTGEVVDEVISRGKHLFIRTGTA 60 MPEGDTVW A LR LA + LT CD+RVPR+A VDL+G VD V SRGKHL IR G A Sbjct 6 MPEGDTVWRAANELRAALAEKVLTTCDVRVPRYATVDLSGHRVDSVASRGKHLLIRVGEA 65 Query 61 SIHSHLQMDGSWRV---GNRPVRVDHRARIILEANQQEQAIRVVGVDLGLLEVIDRHNDG 117 SIH+HL+M+G W++ G R R H+ARI+L E ++ VG LG+ E+++ + Sbjct 66 SIHTHLKMEGQWQIYRPGERWRRPAHQARILLAT---EDSV-AVGFSLGITEILELGQEQ 121 Query 118 AVVAHLGPDLLADDWDPQRAAANLIVAPDRPIAEALLDQRVLAGIGNVYCNELCFVSGVL 177 V HLGPDLL DWD AA NL A PI ALLDQRV+AG+GNVY NE+CF+ G+ Sbjct 122 EAVGHLGPDLLGTDWDSSVAARNLRAADSVPIGIALLDQRVMAGLGNVYRNEICFLRGIH 181 Query 178 PTAPVSAVADPRRLVTRARDMLWVNRFRWNRCTTGDTRAGRRLWVYGRAGQGCRRCGTLI 237 P P + +V + + VN+ R R TTGDTR GR+ WVYGR G+ CRRCGT I Sbjct 182 PKTPTHLAGNLDAIVDLSFRTINVNKSRRIRVTTGDTRPGRQTWVYGRRGKPCRRCGTRI 241 Query 238 AYDT-----TDERVRYWCPACQ 254 DT ER ++CPACQ Sbjct 242 TEDTLGPDQLTERNIFFCPACQ 263 >gi|226305585|ref|YP_002765545.1| DNA glycosylase [Rhodococcus erythropolis PR4] gi|226184702|dbj|BAH32806.1| putative DNA glycosylase [Rhodococcus erythropolis PR4] Length=263 Score = 244 bits (622), Expect = 1e-62, Method: Compositional matrix adjust. Identities = 135/262 (52%), Positives = 166/262 (64%), Gaps = 12/262 (4%) Query 1 MPEGDTVWHTAATLRRHLAGRTLTRCDIRVPRFAAVDLTGEVVDEVISRGKHLFIRTGTA 60 MPEGDTVW A LR LA + LT CD+RVPR+A VDL+G VD V SRGKHL IR G A Sbjct 1 MPEGDTVWRAANDLRAALAEKVLTTCDVRVPRYATVDLSGHRVDSVASRGKHLLIRVGEA 60 Query 61 SIHSHLQMDGSWRV---GNRPVRVDHRARIILEANQQEQAIRVVGVDLGLLEVIDRHNDG 117 SIH+HL+M+G W++ G R R H+ARIIL E ++ VG LG+ E+++ + Sbjct 61 SIHTHLKMEGQWQIYRPGERWRRPAHQARIILAT---EDSV-AVGFSLGVTEILELGQEQ 116 Query 118 AVVAHLGPDLLADDWDPQRAAANLIVAPDRPIAEALLDQRVLAGIGNVYCNELCFVSGVL 177 V HLGPDLL DWD AA NL A PI ALLDQRV+AG+GNVY NE+CF+ G+ Sbjct 117 EAVGHLGPDLLGTDWDSSVAARNLRAADSVPIGIALLDQRVMAGLGNVYRNEICFLRGIH 176 Query 178 PTAPVSAVADPRRLVTRARDMLWVNRFRWNRCTTGDTRAGRRLWVYGRAGQGCRRCGTLI 237 P P + +V + + VN+ R R TTGDTR GR+ WVYGR G+ CRRCGT I Sbjct 177 PKTPTHRAGNLDAIVDLSFRTINVNKSRRIRVTTGDTRPGRQTWVYGRRGKPCRRCGTRI 236 Query 238 AYDT-----TDERVRYWCPACQ 254 DT ER ++CPACQ Sbjct 237 REDTLGPDQLTERNIFFCPACQ 258 >gi|311743597|ref|ZP_07717403.1| endonuclease VIII [Aeromicrobium marinum DSM 15272] gi|311312727|gb|EFQ82638.1| endonuclease VIII [Aeromicrobium marinum DSM 15272] Length=259 Score = 242 bits (617), Expect = 4e-62, Method: Compositional matrix adjust. Identities = 132/262 (51%), Positives = 160/262 (62%), Gaps = 12/262 (4%) Query 1 MPEGDTVWHTAATLRRHLAGRTLTRCDIRVPRFAAVDLTGEVVDEVISRGKHLFIRTGTA 60 MPEGDTVW TA L LAGR L D+RVP FA DLTG VDEV+SRGKHL R G+ Sbjct 1 MPEGDTVWRTAHHLHEVLAGRDLVTFDLRVPDFATSDLTGHRVDEVVSRGKHLLTRIGSF 60 Query 61 SIHSHLQMDGSWRVGNRPV---RVDHRARIILEANQQEQAIRVVGVDLGLLEVIDRHNDG 117 ++H+HL+M+G+W V R R H AR +LE + + +G LG++E++ R + Sbjct 61 TLHTHLKMEGAWHVQPRGAGWRRPAHSARAVLETTEHQ----AIGYSLGVVELVPRDAED 116 Query 118 AVVAHLGPDLLADDWDPQRAAANLIVAPDRPIAEALLDQRVLAGIGNVYCNELCFVSGVL 177 VV HLGPDLL DWD A L P RP+ ALLDQR LAG+GN Y NEL F +G+ Sbjct 117 TVVGHLGPDLLGPDWDAAEAVRRLRTDPTRPVFLALLDQRNLAGLGNEYVNELLFTAGLA 176 Query 178 PTAPVSAVADPRRLVTRARDMLWVNRFRWNRCTTGDTRAGRRLWVYGRAGQGCRRCGTLI 237 PT PVS V D RLV R R ML VN+ R R TG TR G+ WVY R + CRRCGT I Sbjct 177 PTRPVSDVPDLPRLVARGRQMLDVNKARVERSFTGSTRPGQERWVYSRERRPCRRCGTRI 236 Query 238 AY-----DTTDERVRYWCPACQ 254 + D +R +WCP CQ Sbjct 237 SQGSLGDDPVRQRNTFWCPHCQ 258 >gi|345009750|ref|YP_004812104.1| H2TH DNA-binding DNA glycosylase/AP lyase [Streptomyces violaceusniger Tu 4113] gi|344036099|gb|AEM81824.1| H2TH DNA-binding DNA glycosylase/AP lyase [Streptomyces violaceusniger Tu 4113] Length=297 Score = 238 bits (606), Expect = 7e-61, Method: Compositional matrix adjust. Identities = 136/263 (52%), Positives = 161/263 (62%), Gaps = 13/263 (4%) Query 1 MPEGDTVWHTAATLRRHLAGRTLTRCDIRVPRFAAVDLTGEVVDEVISRGKHLFIRT-GT 59 MPEGDTVW TA L + LAG LTR D+RVPR A DLTG V EV+ RGKHL R G Sbjct 30 MPEGDTVWQTAQRLHQALAGPPLTRSDLRVPRLATADLTGRRVLEVVPRGKHLLTRVEGG 89 Query 60 ASIHSHLQMDGSWRVGNRPVR----VDHRARIILEANQQEQAIRVVGVDLGLLEVIDRHN 115 ++HSHL+MDGSW+V R H+ R IL A VG L +LE++ + Sbjct 90 LTLHSHLRMDGSWQVYGPGERWRGGPHHQIRAILAT----AAHTAVGYRLPVLELLRTGD 145 Query 116 DGAVVAHLGPDLLADDWDPQRAAANLIVAPDRPIAEALLDQRVLAGIGNVYCNELCFVSG 175 + VV HLGPDLL DWDP A L+ P RP+ EALLDQR LAGIGNVY +ELCFV Sbjct 146 EDKVVGHLGPDLLGPDWDPDEALRRLLADPSRPLGEALLDQRNLAGIGNVYKSELCFVLR 205 Query 176 VLPTAPVSAVADPRRLVTRARDMLWVNRFRWNRCTTGDTRAGRRLWVYGRAGQGCRRCGT 235 V P P+ V+ P RLV A+ +L NR R R TT + R RRLWVYGR G+ C RCGT Sbjct 206 VSPWLPIGEVSSPERLVAHAKKLLEANRNRRARVTTAEPRPDRRLWVYGRPGRPCLRCGT 265 Query 236 LI-AYD---TTDERVRYWCPACQ 254 + A D ER +WCP+CQ Sbjct 266 PVRAADQGRAGQERSTFWCPSCQ 288 >gi|111023233|ref|YP_706205.1| DNA-formamidopyrimidine glycosylase [Rhodococcus jostii RHA1] gi|110822763|gb|ABG98047.1| probable DNA-formamidopyrimidine glycosylase [Rhodococcus jostii RHA1] Length=249 Score = 237 bits (605), Expect = 1e-60, Method: Compositional matrix adjust. Identities = 128/257 (50%), Positives = 166/257 (65%), Gaps = 16/257 (6%) Query 1 MPEGDTVWHTAATLRRHLAGRTLTRCDIRVPRFAAVDLTGEVVDEVISRGKHLFIRTGTA 60 MPEGDTVW TA +LR L G+ LTRCD+RVPR+A VDL+G++VDEV+SRGKHL IR G Sbjct 1 MPEGDTVWRTANSLRDALEGKVLTRCDVRVPRYATVDLSGQLVDEVVSRGKHLLIRVGDY 60 Query 61 SIHSHLQMDGSWRV---GNRPVRVDHRARIILEANQQEQAIRVVGVDLGLLEVIDRHNDG 117 SIH+HL+M+G+W + + R H+ARI+L + VG LG+ E++ R ++ Sbjct 61 SIHTHLKMEGAWHIYAPDTKWRRPTHQARIVLATEDRV----AVGFSLGITEILGRDDEE 116 Query 118 AVVAHLGPDLLADDWDPQRAAANLIVAPDRPIAEALLDQRVLAGIGNVYCNELCFVSGVL 177 + V HLGPDLL DWD RA NL A D+PI AL+DQR LAG+GNVY NE+CF+ GV Sbjct 117 SAVGHLGPDLLGPDWDADRAIRNLRAAGDQPIGLALVDQRNLAGLGNVYRNEVCFLRGVH 176 Query 178 PTAPVSAVADPRRLVTRARDMLWVNRFRWNRCTTGDTRAGRRLWVYGRAGQGCRRCGTLI 237 P P S VAD LVT A M+ +++ R R WVYGRAG+ CRRCGT+I Sbjct 177 PYTPSSEVADLPALVTLAHRMIHIDKNNSIR---------HRPWVYGRAGKRCRRCGTVI 227 Query 238 AYDTTDERVRYWCPACQ 254 ++ ++C CQ Sbjct 228 EGHDLGQQQIFFCTYCQ 244 >gi|50955599|ref|YP_062887.1| DNA glycosylase [Leifsonia xyli subsp. xyli str. CTCB07] gi|50952081|gb|AAT89782.1| DNA glycosylase [Leifsonia xyli subsp. xyli str. CTCB07] Length=261 Score = 237 bits (605), Expect = 1e-60, Method: Compositional matrix adjust. Identities = 141/265 (54%), Positives = 162/265 (62%), Gaps = 16/265 (6%) Query 1 MPEGDTVWHTAATLRRHLAGRTLTRCDIRVPRFAAVDLTGEVVDEVISRGKHLFIRTGTA 60 MPEGDTV+ A LRR LAGR LT D RVP +A VDL+G+ VDEV+SRGKHL IR G Sbjct 1 MPEGDTVYQAADRLRRALAGRVLTATDFRVPAYATVDLSGQRVDEVVSRGKHLLIRVGGH 60 Query 61 SIHSHLQMDGSWRV---GNRPVRVDHRARIILEANQQEQAIRVVGVDLGLLEVIDRHNDG 117 S+HSHL+MDGSW V G R H+AR++L + E VG LG L+++ R + Sbjct 61 SVHSHLKMDGSWEVYPPGGRWRHPAHQARVVLRTAEGE----AVGFLLGTLDLLPRERED 116 Query 118 AVVAHLGPDLLADDWDPQRAAA---NLIVAPDRPIAEALLDQRVLAGIGNVYCNELCFVS 174 V LGP+LL WD AA L P P+A ALLDQR LAGIGNVY NELCF+ Sbjct 117 EAVDDLGPNLLDPGWDAASAAEAVRRLRERPGAPVAVALLDQRALAGIGNVYANELCFLR 176 Query 175 GVLPTAPVSAVADPRRLVTRARDMLWVNRFRWNRCTTGDTRAGRRLWVYGRAGQGCRRCG 234 G+LPT PV AD V A +L NR R R TTGDTR GR WVYGR GQ CRRCG Sbjct 177 GMLPTRPVRE-ADIPAAVDLAHRLLAANRDRSVRVTTGDTRRGRTTWVYGRQGQPCRRCG 235 Query 235 TLI-----AYDTTDERVRYWCPACQ 254 T I Y ERV +CP CQ Sbjct 236 TPIRRGRLGYTELTERVTSFCPVCQ 260 >gi|297156756|gb|ADI06468.1| endonuclease VIII and DNA N-glycosylase with an AP lyase activity [Streptomyces bingchenggensis BCW-1] Length=269 Score = 236 bits (603), Expect = 2e-60, Method: Compositional matrix adjust. Identities = 132/262 (51%), Positives = 163/262 (63%), Gaps = 12/262 (4%) Query 1 MPEGDTVWHTAATLRRHLAGRTLTRCDIRVPRFAAVDLTGEVVDEVISRGKHLFIR-TGT 59 MPEGDTVW TA L + LAGR LT CD+R+PR A VDL G V +V +RGKHL R G Sbjct 1 MPEGDTVWRTARRLDQALAGRQLTGCDLRIPRLATVDLAGRQVMDVTARGKHLLTRLEGG 60 Query 60 ASIHSHLQMDGSWRVGNRPVR----VDHRARIILEANQQEQAIRVVGVDLGLLEVIDRHN 115 ++HSHL+MDG+W + + R H+ R IL ++ VG L +LE++ + Sbjct 61 LTLHSHLRMDGAWHLYDPGERWRGGPLHQVRAILSTAERT----AVGYRLPVLELLRTTD 116 Query 116 DGAVVAHLGPDLLADDWDPQRAAANLIVAPDRPIAEALLDQRVLAGIGNVYCNELCFVSG 175 + V HLGPDLL DWDP A L+ P RP+ EALLDQR LAGIGNVY +ELCF+ Sbjct 117 EDRAVGHLGPDLLGPDWDPHEALRRLLADPARPLGEALLDQRNLAGIGNVYKSELCFLVR 176 Query 176 VLPTAPVSAVADPRRLVTRARDMLWVNRFRWNRCTTGDTRAGRRLWVYGRAGQGCRRCGT 235 V P PV V P RLV A+ +L N+ R R TT ++RA RRLWVYGRAG+ C RCGT Sbjct 177 VSPWLPVGQVPSPERLVALAKRLLEANKARPARITTAESRADRRLWVYGRAGKPCLRCGT 236 Query 236 LIAYD---TTDERVRYWCPACQ 254 + + ER YWCPACQ Sbjct 237 PVRMEQGRADKERSTYWCPACQ 258 >gi|148273833|ref|YP_001223394.1| putative endonuclease VIII/DNA glycosylase [Clavibacter michiganensis subsp. michiganensis NCPPB 382] gi|147831763|emb|CAN02732.1| putative endonuclease VIII/DNA glycosylase [Clavibacter michiganensis subsp. michiganensis NCPPB 382] Length=267 Score = 233 bits (593), Expect = 3e-59, Method: Compositional matrix adjust. Identities = 137/272 (51%), Positives = 162/272 (60%), Gaps = 24/272 (8%) Query 1 MPEGDTVWHTAATLRRHLAGRTLTRCDIRVPRFAAVDLTGEVVDEVISRGKHLFIRTGTA 60 MPEGDTVW TAA L + G+ LTR D RVP+FA +DL G+ VDEV+S GKH+ R G Sbjct 1 MPEGDTVWRTAAHLHEAIGGQVLTRSDFRVPKFATLDLAGQEVDEVVSVGKHILHRIGDL 60 Query 61 SIHSHLQMDGSWRV---GNRPVRVDHRARIILEANQQEQAIRVVGVDLGLLEVIDRHNDG 117 +IHSHL+M+GSW + G R AR++LE ++ VG LG+LEVI R + Sbjct 61 TIHSHLKMEGSWHIYQHGTPWRRPAFEARVVLETAERV----TVGFALGVLEVIPRDQEH 116 Query 118 AVVAHLGPDLLADDWDPQRAAANLIV-----APDRPIAEALLDQRVLAGIGNVYCNELCF 172 VV HLGPD+L DW AAA IV P+R I ALLDQR AGIGNVY ELCF Sbjct 117 TVVGHLGPDILGPDWG--HAAAEEIVRRISAQPERAIGLALLDQRNAAGIGNVYRAELCF 174 Query 173 VSGVLPTAPVSAVADPRRLVTRARDMLWVNRFRWNRCTTGDTRAGRRLWVYGRAGQGCRR 232 + GVLPT PV+ V D +V AR + NR R R TTGD R GR WVYGR G+ C R Sbjct 175 LRGVLPTRPVAEVPDLPAMVALARRTMRANRDRIERTTTGDLRRGRTDWVYGRKGKPCLR 234 Query 233 CGTLIAYDT----------TDERVRYWCPACQ 254 CGT I +RV YWCP CQ Sbjct 235 CGTRIQQGQLCDPVRPGMGAQDRVTYWCPRCQ 266 >gi|269127507|ref|YP_003300877.1| DNA-(apurinic or apyrimidinic site) lyase [Thermomonospora curvata DSM 43183] gi|268312465|gb|ACY98839.1| DNA-(apurinic or apyrimidinic site) lyase [Thermomonospora curvata DSM 43183] Length=259 Score = 232 bits (591), Expect = 4e-59, Method: Compositional matrix adjust. Identities = 132/260 (51%), Positives = 159/260 (62%), Gaps = 10/260 (3%) Query 1 MPEGDTVWHTAATLRRHLAGRTLTRCDIRVPRFAAVDLTGEVVDEVISRGKHLFIRT-GT 59 MPEGDTVW A L R LAG LT CD+RVPR+A DL G+ V E +SRGKHL IR G Sbjct 1 MPEGDTVWLAARRLHRALAGWALTVCDVRVPRYATTDLRGQRVREAVSRGKHLLIRVDGG 60 Query 60 ASIHSHLQMDGSWRV-GNRPVRVDHRARIILEANQQEQAIRVVGVDLGLLEVIDRHNDGA 118 S+H HL+MDG W + PV DHR R+ L N++ A+ G LG++EV+ + Sbjct 61 LSVHVHLKMDGRWLIRPAGPVPRDHRIRLAL-GNERHLAL---GYRLGVVEVLPTAAEEC 116 Query 119 VVAHLGPDLLADDWDPQRAAANLIVAPDRPIAEALLDQRVLAGIGNVYCNELCFVSGVLP 178 V HLGPDLL DWDPQ A L P+R I EA++DQ VLAGIGN+Y +ELCF+ GV P Sbjct 117 AVGHLGPDLLGPDWDPQEAVRRLRARPERAIGEAVMDQSVLAGIGNIYKSELCFLRGVHP 176 Query 179 TAPVSAVADPRRLVTRARDMLWVNRFRWNRCTTGDTRAGRRLWVYGRAGQGCRRCGTLIA 238 PV+ D LV A +L N+ R TTGD R GR WVYGRAG+ CRRCG I Sbjct 177 WRPVAEAGDLHALVDLAHRLLEANKNRHGHVTTGDLRPGRTHWVYGRAGRPCRRCGARIE 236 Query 239 YDTTD----ERVRYWCPACQ 254 ER+ +WCP CQ Sbjct 237 QAEQGPPGWERLTFWCPGCQ 256 >gi|170780851|ref|YP_001709183.1| DNA glycosylase [Clavibacter michiganensis subsp. sepedonicus] gi|169155419|emb|CAQ00526.1| DNA glycosylase [Clavibacter michiganensis subsp. sepedonicus] Length=267 Score = 231 bits (589), Expect = 8e-59, Method: Compositional matrix adjust. Identities = 131/270 (49%), Positives = 158/270 (59%), Gaps = 20/270 (7%) Query 1 MPEGDTVWHTAATLRRHLAGRTLTRCDIRVPRFAAVDLTGEVVDEVISRGKHLFIRTGTA 60 MPEGDTVW TA L + G+ LTR D RVP++A +DL G+ VDEV+S GKH+ R G Sbjct 1 MPEGDTVWRTATHLHEAIGGQVLTRSDFRVPKYATLDLAGQEVDEVVSVGKHILHRVGDL 60 Query 61 SIHSHLQMDGSWRV---GNRPVRVDHRARIILEANQQEQAIRVVGVDLGLLEVIDRHNDG 117 +IHSHL+M+GSW + G R AR++LE ++ VG LG+LEVI R + Sbjct 61 TIHSHLKMEGSWHIYQHGTAWRRPAFEARVVLETAERV----TVGFSLGVLEVIPRDQEH 116 Query 118 AVVAHLGPDLLADDWDPQRAAA---NLIVAPDRPIAEALLDQRVLAGIGNVYCNELCFVS 174 VV HLGPD+L DW + A + PDR I ALLDQR AGIGNVY ELCF+ Sbjct 117 TVVGHLGPDILGPDWGDEAAEEIVRRIAAQPDRAIGLALLDQRNAAGIGNVYRAELCFLR 176 Query 175 GVLPTAPVSAVADPRRLVTRARDMLWVNRFRWNRCTTGDTRAGRRLWVYGRAGQGCRRCG 234 GVLPT PV V D ++ AR + NR R R TTGD R GR WVYGR G+ C RCG Sbjct 177 GVLPTRPVREVPDLPAMIALARRTMRANRDRIERTTTGDLRRGRTDWVYGRKGKACLRCG 236 Query 235 TLIAYDT----------TDERVRYWCPACQ 254 T I +RV YWCP CQ Sbjct 237 TRILQGQLGDPVRPGMGAQDRVTYWCPRCQ 266 >gi|302542087|ref|ZP_07294429.1| endonuclease VIII [Streptomyces hygroscopicus ATCC 53653] gi|302459705|gb|EFL22798.1| endonuclease VIII [Streptomyces himastatinicus ATCC 53653] Length=273 Score = 229 bits (585), Expect = 2e-58, Method: Compositional matrix adjust. Identities = 133/263 (51%), Positives = 158/263 (61%), Gaps = 13/263 (4%) Query 1 MPEGDTVWHTAATLRRHLAGRTLTRCDIRVPRFAAVDLTGEVVDEVISRGKHLFIRT-GT 59 MPEGDTVW TA L LAG LT CD+RVPR A VDLTG V EV++RGKHL R G Sbjct 5 MPEGDTVWQTARRLDDALAGPPLTGCDLRVPRLATVDLTGRRVLEVVARGKHLLTRVEGG 64 Query 60 ASIHSHLQMDGSWRVGNRPVR----VDHRARIILEANQQEQAIRVVGVDLGLLEVIDRHN 115 ++HSHL+MDG+W V R H+ R +L ++ VG L +LE++ + Sbjct 65 LTLHSHLRMDGAWLVYGHGERWRGGPQHQIRAVLATAERT----AVGYRLPVLELLRTAD 120 Query 116 DGAVVAHLGPDLLADDWDPQRAAANLIVAPDRPIAEALLDQRVLAGIGNVYCNELCFVSG 175 + V HLGPDLL DWDP A L+ P RP+ EALLDQR LAGIGNVY ELCFV Sbjct 121 EDRAVGHLGPDLLGPDWDPDEALGRLLADPSRPVGEALLDQRNLAGIGNVYKCELCFVLR 180 Query 176 VLPTAPVSAVADPRRLVTRARDMLWVNRFRWNRCTTGDTRAGRRLWVYGRAGQGCRRCGT 235 + P P+ V P RLV A+ +L NR R R TT R RRLWVYGRAG+ C RCGT Sbjct 181 IPPWLPIGRVPSPERLVAVAKRLLEANRTRRARVTTAHARPDRRLWVYGRAGRPCLRCGT 240 Query 236 LI-AYD---TTDERVRYWCPACQ 254 + A D ER +WCP CQ Sbjct 241 PVRAADQGRAGQERTTFWCPVCQ 263 >gi|296138322|ref|YP_003645565.1| DNA glycosylase/AP lyase, H2TH DNA-binding protein [Tsukamurella paurometabola DSM 20162] gi|296026456|gb|ADG77226.1| DNA glycosylase/AP lyase, H2TH DNA-binding protein [Tsukamurella paurometabola DSM 20162] Length=261 Score = 228 bits (582), Expect = 4e-58, Method: Compositional matrix adjust. Identities = 136/262 (52%), Positives = 159/262 (61%), Gaps = 12/262 (4%) Query 1 MPEGDTVWHTAATLRRHLAGRTLTRCDIRVPRFAAVDLTGEVVDEVISRGKHLFIRTGTA 60 MPEGDT+ + AA LR LAGR LT CD+RVPR+A VDLTG VD+V +RGKHL I G Sbjct 1 MPEGDTLHNLAARLRPVLAGRVLTGCDLRVPRYATVDLTGRTVDDVSARGKHLLIAAGDL 60 Query 61 SIHSHLQMDGSWRV---GNRPVRVDHRARIILEANQQEQAIRVVGVDLGLLEVIDRHNDG 117 ++HSHL+M+G W V G R R H AR +L + + VVG LG LEV+ Sbjct 61 TLHSHLKMEGQWHVYRPGERWRRPGHTARAVLAVDGAQ----VVGFSLGFLEVLRTAAVD 116 Query 118 AVVAHLGPDLLADDWDPQRAAANLIVAPDRPIAEALLDQRVLAGIGNVYCNELCFVSGVL 177 +AHLGPD L WDP+RAA NL P RP+ ALLDQR LAGIGNVY NELCFV GV Sbjct 117 DALAHLGPDPLGPQWDPERAAENLAATPARPVGLALLDQRNLAGIGNVYRNELCFVRGVH 176 Query 178 PTAPVSAVADPRRLVTRARDMLWVNRFRWNRCTTGDTRAGRRLWVYGRAGQGCRRCGTLI 237 P V+A D R V A +L N R R TTG R G R +VY RA + C RCGT I Sbjct 177 PAMEVAACGDLRGWVDDAARLLRANAGRSVRVTTGVDRNGLRAFVYDRARRPCLRCGTAI 236 Query 238 A-----YDTTDERVRYWCPACQ 254 + D ER +WCP CQ Sbjct 237 SAGSLGADGEAERTIWWCPRCQ 258 >gi|262201744|ref|YP_003272952.1| formamidopyrimidine-DNA glycosylase catalytic domain-containing protein [Gordonia bronchialis DSM 43247] gi|262085091|gb|ACY21059.1| Formamidopyrimidine-DNA glycosylase catalytic domain protein [Gordonia bronchialis DSM 43247] Length=261 Score = 228 bits (581), Expect = 7e-58, Method: Compositional matrix adjust. Identities = 133/268 (50%), Positives = 164/268 (62%), Gaps = 20/268 (7%) Query 1 MPEGDTVWHTAATLRRHLAGRTLTRCDIRVPRFAAVDLTGEVVDEVISRGKHLFIRTG-- 58 MPEGDTV+ A LRR LAG+ LT C RVPR+A VD G V V SRGKHL I Sbjct 1 MPEGDTVYAAADRLRRALAGQVLTYCQFRVPRYATVDFAGHTVTGVRSRGKHLLIDLADP 60 Query 59 ----TASIHSHLQMDGSW---RVGNRPVRVDHRARIILEANQQEQAIRVVGVDLGLLEVI 111 SIHSHL+M+G+W RVG R R H ARI+L + E VG +LG+L+++ Sbjct 61 QGNRAPSIHSHLKMEGAWHVHRVGARWRRPGHHARIVLRTSTYE----AVGFELGILDLL 116 Query 112 DRHNDGAVVAHLGPDLLADDWDPQRAAANLIVAPDRPIAEALLDQRVLAGIGNVYCNELC 171 D + A +++LGPDLL DDWD + A + P I ALLDQR++AG+GNV+ E+C Sbjct 117 D--DPDAALSYLGPDLLGDDWDAEEAIRRIRARPAEAIGLALLDQRLMAGVGNVFRCEIC 174 Query 172 FVSGVLPTAPVSAVADPRRLVTRARDMLWVNRFRWNRCTTGDTRAGRRLWVYGRAGQGCR 231 ++ GVLPT PV+ V P +V +R +LW NR R R TTG T R WVYGR GQ CR Sbjct 175 YLRGVLPTTPVADVDVP-GMVETSRKLLWNNRTRTARSTTGQTAPNARTWVYGRRGQLCR 233 Query 232 RCGTLIAY----DTTDERVRYWCPACQR 255 RC TLI D ERV Y+CP CQR Sbjct 234 RCATLIERGFLGDEGTERVIYFCPTCQR 261 >gi|226365740|ref|YP_002783523.1| DNA glycosylase [Rhodococcus opacus B4] gi|226244230|dbj|BAH54578.1| putative DNA glycosylase [Rhodococcus opacus B4] Length=249 Score = 227 bits (578), Expect = 1e-57, Method: Compositional matrix adjust. Identities = 123/257 (48%), Positives = 161/257 (63%), Gaps = 16/257 (6%) Query 1 MPEGDTVWHTAATLRRHLAGRTLTRCDIRVPRFAAVDLTGEVVDEVISRGKHLFIRTGTA 60 MPEGDTVW TA +LR L G+ LTRCD+RVPR+A VDL+G+VVDEV+SRGKHL IR G Sbjct 1 MPEGDTVWRTANSLRDALEGKVLTRCDVRVPRYATVDLSGQVVDEVVSRGKHLLIRVGDY 60 Query 61 SIHSHLQMDGSWRV---GNRPVRVDHRARIILEANQQEQAIRVVGVDLGLLEVIDRHNDG 117 SIH+HL+M+G+W + +R R H+ARI+L + VG LG+ E++ R ++ Sbjct 61 SIHTHLKMEGAWHIYAPDSRWRRPTHQARIVLSTEDRV----AVGFSLGITEILARDDEE 116 Query 118 AVVAHLGPDLLADDWDPQRAAANLIVAPDRPIAEALLDQRVLAGIGNVYCNELCFVSGVL 177 + V HLGPD+L WD A NL A D+PI AL+DQR LAG+GNVY NE+CF+ GV Sbjct 117 SAVGHLGPDVLGPGWDADTAIRNLRAAGDQPIGLALVDQRNLAGLGNVYRNEVCFLRGVH 176 Query 178 PTAPVSAVADPRRLVTRARDMLWVNRFRWNRCTTGDTRAGRRLWVYGRAGQGCRRCGTLI 237 P P + V D LV A M+ ++ + R WVYGRAGQ CRRC T+I Sbjct 177 PYTPAAEVTDLPALVALAHRMIHADK---------NNSVRHRPWVYGRAGQRCRRCRTVI 227 Query 238 AYDTTDERVRYWCPACQ 254 ++ ++C CQ Sbjct 228 EGHDLGQQQIFFCTYCQ 244 >gi|343926675|ref|ZP_08766173.1| putative DNA glycosylase [Gordonia alkanivorans NBRC 16433] gi|343763427|dbj|GAA13099.1| putative DNA glycosylase [Gordonia alkanivorans NBRC 16433] Length=263 Score = 224 bits (570), Expect = 1e-56, Method: Compositional matrix adjust. Identities = 129/269 (48%), Positives = 164/269 (61%), Gaps = 22/269 (8%) Query 1 MPEGDTVWHTAATLRRHLAGRTLTRCDIRVPRFAAVDLTGEVVDEVISRGKHLFIRTGTA 60 MPEGDTV+ AA LR+ L GRTLT R+P A DL+G V V SRGKHL I G + Sbjct 1 MPEGDTVFAAAARLRQGLEGRTLTSTQFRIPSLATSDLSGRTVVSVRSRGKHLLIDVGES 60 Query 61 --------SIHSHLQMDGSWRV---GNRPVRVDHRARIILEANQQEQAIRVVGVDLGLLE 109 SIHSHL+M+G W V G + R ++AR++L + E VG DLG LE Sbjct 61 EPGAGDALSIHSHLKMEGVWHVHRRGQKWRRPAYQARVVLRTDDHE----AVGFDLGTLE 116 Query 110 VIDRHNDGAVVAHLGPDLLADDWDPQRAAANLIVAPDRPIAEALLDQRVLAGIGNVYCNE 169 ++ + A +A+LGPDLLADD+D + A L PD+ I ALLDQR++AG+GNV+ +E Sbjct 117 LL--ADPDAALAYLGPDLLADDFDREEAIRRLAADPDQTIGAALLDQRLMAGVGNVFRSE 174 Query 170 LCFVSGVLPTAPVSAVADPRRLVTRARDMLWVNRFRWNRCTTGDTRAGRRLWVYGRAGQG 229 +C++ GVLPT PV V D +V +R +LW NR R R TTG T R+WVYGR GQ Sbjct 175 ICYLRGVLPTRPVGEV-DLGPMVDLSRRLLWANRMRSARTTTGQTSPNGRMWVYGRKGQL 233 Query 230 CRRCGTLIAY----DTTDERVRYWCPACQ 254 CRRC T+I T +R YWCP CQ Sbjct 234 CRRCATIIKRGEIPSTGGDRSIYWCPRCQ 262 >gi|333921179|ref|YP_004494760.1| fomramidopyrimidine-DNA glycosylase [Amycolicicoccus subflavus DQS3-9A1] gi|333483400|gb|AEF41960.1| Formamidopyrimidine-DNA glycosylase [Amycolicicoccus subflavus DQS3-9A1] Length=270 Score = 222 bits (566), Expect = 4e-56, Method: Compositional matrix adjust. Identities = 124/270 (46%), Positives = 160/270 (60%), Gaps = 20/270 (7%) Query 1 MPEGDTVWHTAATLRRHLAGRTLTRCDIRVPRFAAVDLTGEVVDEVISRGKHLFIRTGTA 60 MPEGDTV+ A LR L + LTR RV ++A ++ G + V GKHLFI+ G Sbjct 1 MPEGDTVYRAATNLRAALDQKVLTRTQFRVDKYANLNFAGLRISRVWPHGKHLFIQAGDH 60 Query 61 SIHSHLQMDGSW---RVGNRPVRVDHRARIILEANQQEQAIRVVGVDLGLLEVIDRHNDG 117 IHSHL+M+G+W + G + + +AR++LEA+ + VG LG+L V+ Sbjct 61 VIHSHLKMEGAWHTYKPGEKWRKPGWQARVVLEADGSQ----AVGFSLGILSVLSAAEAP 116 Query 118 AVVAHLGPDLLADDWDPQRAAANLIVAPDRPIAEALLDQRVLAGIGNVYCNELCFVSGVL 177 +V AHLGPDLL+D+WD A + AP+R I ALLDQR LAGIGNVY +ELCF+ G+ Sbjct 117 SVTAHLGPDLLSDNWDAATARDRIGSAPERAIGMALLDQRNLAGIGNVYRSELCFLRGLD 176 Query 178 PTAPVSAVADPRRLVTRARDMLWVNRFRWNRCTTGDTRAGRRLWVYGRAGQGCRRCGTL- 236 P P S VAD L+ +R MLW N+ R RCTTG+ R G+ LWVYGR CRRCGTL Sbjct 177 PLTPTSEVADLDGLLDLSRRMLWANKDRTQRCTTGNLRRGQELWVYGRERNPCRRCGTLI 236 Query 237 ------------IAYDTTDERVRYWCPACQ 254 I+ DER+ Y CP CQ Sbjct 237 ERRIISESGYQSISVPNADERLVYVCPRCQ 266 >gi|88854733|ref|ZP_01129399.1| DNA glycosylase [marine actinobacterium PHSC20C1] gi|88815894|gb|EAR25750.1| DNA glycosylase [marine actinobacterium PHSC20C1] Length=272 Score = 221 bits (563), Expect = 7e-56, Method: Compositional matrix adjust. Identities = 128/276 (47%), Positives = 162/276 (59%), Gaps = 25/276 (9%) Query 1 MPEGDTVWHTAATLRRHLAGRTLTRCDIRVPRFAAVDLTGEVVDEVISRGKHLFIRTGT- 59 MPEGD+V+ AA LR L G+ LTR D RVP FA +DL+G+ V V+ RGKHL IR Sbjct 1 MPEGDSVYKAAAKLRAALDGQVLTRTDFRVPAFATLDLSGQTVTSVVPRGKHLLIRVAED 60 Query 60 ------------ASIHSHLQMDGSWRV---GNRPVRVDHRARIILEANQQEQAIRVVGVD 104 +IHSHL+M+G W++ G R + + AR +L + VG + Sbjct 61 ADASSSREPGSGHTIHSHLKMEGVWQIYANGERWRKPAYLARAVLSTASKT----AVGFE 116 Query 105 LGLLEVIDRHNDGAVVAHLGPDLLADDWDPQRAAANLIVAPDRPIAEALLDQRVLAGIGN 164 LGLLEV+ ++ ++V HLGPDLL DWD A ANL+ P RP+A ALLDQR LAG+GN Sbjct 117 LGLLEVVPTASEDSIVGHLGPDLLGPDWDADLALANLLSDPARPVALALLDQRNLAGLGN 176 Query 165 VYCNELCFVSGVLPTAPVSAVADPRRLVTRARDMLWVNRFRWNRCTTGDTRAGRRLWVYG 224 VY NEL F+ G P P+ VADP+RLV A + VN+ R R TG R R WV+G Sbjct 177 VYANELSFLRGFRPDTPIGEVADPKRLVALAHKAISVNKDRPIRNLTGLPRGKSRYWVHG 236 Query 225 RAGQGCRRCGTLI-----AYDTTDERVRYWCPACQR 255 R G C RCGT I TD R +WCP+CQ+ Sbjct 237 RRGDACLRCGTRIESAQLGTGPTDTRFTWWCPSCQK 272 >gi|294815478|ref|ZP_06774121.1| DNA glycosylase [Streptomyces clavuligerus ATCC 27064] gi|326443828|ref|ZP_08218562.1| endonuclease VIII and DNA N-glycosylase with an AP lyase activity [Streptomyces clavuligerus ATCC 27064] gi|294328077|gb|EFG09720.1| DNA glycosylase [Streptomyces clavuligerus ATCC 27064] Length=267 Score = 221 bits (562), Expect = 1e-55, Method: Compositional matrix adjust. Identities = 132/266 (50%), Positives = 162/266 (61%), Gaps = 16/266 (6%) Query 1 MPEGDTVWHTAATLRRHLAGRTLTRCDIRVPRFAAVDLTGEVVDEVISRGKHLFIR-TGT 59 MPEGDTVW TA L LAGR LTR ++RVPR+A DLTG V EV+ RGKHL R G Sbjct 1 MPEGDTVWRTAKRLDTALAGRELTRSELRVPRYATADLTGRRVLEVVPRGKHLLARFEGG 60 Query 60 ASIHSHLQMDGSWRV---GNRP-VRVDHRARIILEANQQEQAIRVVGVDLGLLEVIDRHN 115 ++HSHL+MDG+WRV G RP +H+ R +L + VG L +LE++ + Sbjct 61 LTLHSHLRMDGAWRVFPAGERPRGGPEHQIRAVLGTSSHT----AVGYRLPVLELLRTTD 116 Query 116 DGAVVAHLGPDLLADDWDPQRAAANLIVAPDRPIAEALLDQRVLAGIGNVYCNELCFVSG 175 + VV HLGPDLL DWDP A L+ P RP+ EALLDQR LAGIGNVY EL F++G Sbjct 117 EQKVVGHLGPDLLGPDWDPAAARERLLADPSRPLGEALLDQRNLAGIGNVYKCELAFLAG 176 Query 176 VLPTAPVSAVADP--RRLVTRARDMLWVNRFRWNRCTT-GDTRAGRRLWVYGRAGQGCRR 232 V P PV + + RL+ A +L NR R TT +RAG RL V+GRAG+ C R Sbjct 177 VTPWLPVGELPEGVLERLLATAHRLLEENRDAVERRTTAAGSRAGSRLHVHGRAGRPCPR 236 Query 233 CGTLIAYD----TTDERVRYWCPACQ 254 CGT + DER+ YWCP CQ Sbjct 237 CGTPVRRSGPGRAGDERISYWCPGCQ 262 >gi|330466398|ref|YP_004404141.1| DNA-(apurinic or apyrimidinic site) lyase [Verrucosispora maris AB-18-032] gi|328809369|gb|AEB43541.1| DNA-(apurinic or apyrimidinic site) lyase [Verrucosispora maris AB-18-032] Length=264 Score = 219 bits (557), Expect = 4e-55, Method: Compositional matrix adjust. Identities = 130/264 (50%), Positives = 155/264 (59%), Gaps = 14/264 (5%) Query 1 MPEGDTVWHTAATLRRHLAGRTLTRCDIRVPRFAAVDLTGEVVDEVISRGKHLFIR---- 56 MPEGDTVW+TA L R L G LT D RVP+ A DLTG V + SRGKHL IR Sbjct 1 MPEGDTVWNTARVLARALTGARLTGSDFRVPQLATTDLTGWRVTDCASRGKHLLIRLDEP 60 Query 57 TGTA--SIHSHLQMDGSWRV---GNR-PVRVDHRARIILEANQQEQAIRVVGVDLGLLEV 110 TG A ++HSHL+MDG+WRV G R R H R++L VG L + + Sbjct 61 TGAAHWTLHSHLRMDGTWRVYAPGERWSARPAHLIRVVLSTATST----AVGYHLHEVAL 116 Query 111 IDRHNDGAVVAHLGPDLLADDWDPQRAAANLIVAPDRPIAEALLDQRVLAGIGNVYCNEL 170 + + +V HLGPDLL DWDPQ A L P IAEALLDQR LAG+GN+Y EL Sbjct 117 VPTAEEHRLVGHLGPDLLGTDWDPQEAVRRLADRPAESIAEALLDQRNLAGVGNLYKCEL 176 Query 171 CFVSGVLPTAPVSAVADPRRLVTRARDMLWVNRFRWNRCTTGDTRAGRRLWVYGRAGQGC 230 F+ G+ P V+ V D L+T A D+L NR RW + TTG R G+ +VYGR Q C Sbjct 177 LFLRGINPRTRVADVPDLAGLITLAHDLLAANRGRWTQSTTGSLRRGQTSYVYGRRAQPC 236 Query 231 RRCGTLIAYDTTDERVRYWCPACQ 254 RRCGT I + ERV YWCP CQ Sbjct 237 RRCGTAIRKEELGERVTYWCPRCQ 260 >gi|238063417|ref|ZP_04608126.1| formamidopyrimidine-DNA glycosylase [Micromonospora sp. ATCC 39149] gi|237885228|gb|EEP74056.1| formamidopyrimidine-DNA glycosylase [Micromonospora sp. ATCC 39149] Length=273 Score = 218 bits (556), Expect = 5e-55, Method: Compositional matrix adjust. Identities = 124/265 (47%), Positives = 147/265 (56%), Gaps = 11/265 (4%) Query 1 MPEGDTVWHTAATLRRHLAGRTLTRCDIRVPRFAAVDLTGEVVDEVISRGKHLFIRTGTA 60 MPEGDTVW+TA L R L G LT D RVPR A DL G V E SRGKHL +R Sbjct 1 MPEGDTVWNTARVLGRALGGARLTASDFRVPRLAGTDLAGWTVRESASRGKHLLLRLAAP 60 Query 61 -----------SIHSHLQMDGSWRVGNRPVRVDHRARIILEANQQEQAIRVVGVDLGLLE 109 ++HSHL+MDG+WR R R ++ A + VG L L Sbjct 61 APVGSGGVTGWTLHSHLRMDGAWRAYAPGERWTARPAHLIRAVLRAPDAVAVGYHLHELA 120 Query 110 VIDRHNDGAVVAHLGPDLLADDWDPQRAAANLIVAPDRPIAEALLDQRVLAGIGNVYCNE 169 ++ +GA+V HLGPDLL DWDP A L P+ I EALLDQR LAG+GN+Y E Sbjct 121 LVPTAEEGALVGHLGPDLLGADWDPTEAVRRLAAHPEATIGEALLDQRNLAGVGNLYKCE 180 Query 170 LCFVSGVLPTAPVSAVADPRRLVTRARDMLWVNRFRWNRCTTGDTRAGRRLWVYGRAGQG 229 + F+ GV P PV AV+D V A+ +L NR RW + TTG R G +VYGR Q Sbjct 181 VLFLRGVSPWTPVGAVSDLAGTVALAQRLLAANRGRWTQSTTGSLRRGETSYVYGRRAQP 240 Query 230 CRRCGTLIAYDTTDERVRYWCPACQ 254 CRRCGT I ERV YWCP CQ Sbjct 241 CRRCGTAIRKQELGERVTYWCPICQ 265 >gi|326381980|ref|ZP_08203673.1| Formamidopyrimidine-DNA glycosylase catalytic domain-containing protein [Gordonia neofelifaecis NRRL B-59395] gi|326199406|gb|EGD56587.1| Formamidopyrimidine-DNA glycosylase catalytic domain-containing protein [Gordonia neofelifaecis NRRL B-59395] Length=261 Score = 218 bits (554), Expect = 9e-55, Method: Compositional matrix adjust. Identities = 135/266 (51%), Positives = 160/266 (61%), Gaps = 19/266 (7%) Query 1 MPEGDTVWHTAATLRRHLAGRTLTRCDIRVPRFAAVDLTGEVVDEVISRGKHLFI---RT 57 MPEGDTV+ TA LRR LAGRTL R D RVPR+A DL+G V S GKHLFI R Sbjct 1 MPEGDTVYRTAHRLRRALAGRTLDRTDFRVPRYATADLSGSRAAAVRSVGKHLFIDFERP 60 Query 58 G--TASIHSHLQMDGSW---RVGNRPVRVDHRARIILEANQQEQAIRVVGVDLGLLEVID 112 G S+H+HL M+G W R G+R R H ARI+L + + E VG DL ++E++ Sbjct 61 GGDEISLHTHLMMEGVWEVYRTGSRWRRPAHTARIVLRSGEVE----AVGFDLAVVELLT 116 Query 113 RHNDGAVVAHLGPDLLADDWDPQRAAANLIVAPDRPIAEALLDQRVLAGIGNVYCNELCF 172 + A VAHLGPDLL DDWDP RA A L P+ PI A+LDQR LAGIGNVY +ELCF Sbjct 117 --DPAAAVAHLGPDLLGDDWDPARAVARLSAEPEVPIGVAVLDQRNLAGIGNVYRSELCF 174 Query 173 VSGVLPTAPVSAVADPRRLVTRARDMLWVNRFRWNRCTTGDTRAGRRLWVYGRAGQGCRR 232 + + P PV V P + V A +L NR R R TTG T GR LWVYGR + CRR Sbjct 175 LRRIHPATPVGDVDLP-KTVDLAHRLLVDNRLRAVRSTTGVTARGRELWVYGRDRRPCRR 233 Query 233 CGTLIAYDT----TDERVRYWCPACQ 254 CGT + + R Y CP CQ Sbjct 234 CGTAVMREMLGAPPTARSVYLCPRCQ 259 >gi|302866006|ref|YP_003834643.1| DNA-(apurinic or apyrimidinic site) lyase [Micromonospora aurantiaca ATCC 27029] gi|315502566|ref|YP_004081453.1| DNA-(apurinic or apyrimidinic site) lyase [Micromonospora sp. L5] gi|302568865|gb|ADL45067.1| DNA-(apurinic or apyrimidinic site) lyase [Micromonospora aurantiaca ATCC 27029] gi|315409185|gb|ADU07302.1| DNA-(apurinic or apyrimidinic site) lyase [Micromonospora sp. L5] Length=273 Score = 218 bits (554), Expect = 1e-54, Method: Compositional matrix adjust. Identities = 124/259 (48%), Positives = 149/259 (58%), Gaps = 5/259 (1%) Query 1 MPEGDTVWHTAATLRRHLAGRTLTRCDIRVPRFAAVDLTGEVVDEVISRGKHLFIRTGTA 60 MPEGDTVW+TA L+R LAG LT D RVP+ A DLTG V E SRGKHL +R Sbjct 1 MPEGDTVWNTARVLQRALAGARLTGSDFRVPQLATTDLTGWTVRESASRGKHLLLRLTRT 60 Query 61 -----SIHSHLQMDGSWRVGNRPVRVDHRARIILEANQQEQAIRVVGVDLGLLEVIDRHN 115 ++HSHL+MDG+WR R R ++ + A VG L L ++ Sbjct 61 DAEPWTLHSHLRMDGAWRAYAPGERWSGRPAHLIRVVLRSPAAVAVGYHLHELALVPTAE 120 Query 116 DGAVVAHLGPDLLADDWDPQRAAANLIVAPDRPIAEALLDQRVLAGIGNVYCNELCFVSG 175 + ++V HLGPDLL DWD A L PDR I EALLDQR LAG+GN+Y E+ F+ G Sbjct 121 EESLVGHLGPDLLGPDWDADEAVRRLAADPDRTIGEALLDQRNLAGVGNLYKCEVLFLRG 180 Query 176 VLPTAPVSAVADPRRLVTRARDMLWVNRFRWNRCTTGDTRAGRRLWVYGRAGQGCRRCGT 235 V P PV AV D V A+ +L NR RW + TTG G +VYGR Q CRRCGT Sbjct 181 VSPWTPVGAVPDLTGTVALAQRLLAANRGRWTQSTTGVLHRGGTSYVYGRRAQPCRRCGT 240 Query 236 LIAYDTTDERVRYWCPACQ 254 I + ERV YWCPACQ Sbjct 241 AIRKEELGERVTYWCPACQ 259 >gi|297202801|ref|ZP_06920198.1| formamidopyrimidine-DNA glycosylase [Streptomyces sviceus ATCC 29083] gi|197713889|gb|EDY57923.1| formamidopyrimidine-DNA glycosylase [Streptomyces sviceus ATCC 29083] Length=284 Score = 216 bits (550), Expect = 2e-54, Method: Compositional matrix adjust. Identities = 132/265 (50%), Positives = 161/265 (61%), Gaps = 17/265 (6%) Query 1 MPEGDTVWHTAATLRRHLAGRTLTRCDIRVPRFAAVDLTGEVVDEVISRGKHLFIR-TGT 59 MPEGDTVW A L LA + LTR D+RVP++A DLTG V +V RGKHL R G Sbjct 1 MPEGDTVWQAAKRLHTALADKVLTRSDLRVPKYATADLTGRRVLDVTPRGKHLLTRIEGG 60 Query 60 ASIHSHLQMDGSWRVGNRPVR----VDHRARIILEANQQEQAIRVVGVDLGLLEVIDRHN 115 ++HSHL+MDGSW+V R H+ R IL AN A VG L +LE++ + Sbjct 61 LTLHSHLRMDGSWKVYAENQRWTGGPTHQIRAIL-ANTDRTA---VGYRLPVLELLRTTD 116 Query 116 DGAVVAHLGPDLLADDWDPQRAAANLIVAPDRPIAEALLDQRVLAGIGNVYCNELCFVSG 175 + V HLGPDLL DWDP+RA ANL+ P RP+ EALLDQR LAGIGNVY +ELCF+ G Sbjct 117 EHKAVGHLGPDLLGPDWDPERALANLLRDPARPLGEALLDQRNLAGIGNVYKSELCFLLG 176 Query 176 VLPTAPVSAVADPR--RLVTRARDMLWVNRFRWNRCTTGDTRAGRRLWVYGRAGQGCRRC 233 P PV A+ R +L A+ +L NR R R TTG R G+ L+VYGRA + C RC Sbjct 177 ATPWLPVGALPADRAAQLPALAKKLLEANRDRPVRSTTG--RRGQDLFVYGRAPRPCLRC 234 Query 234 GTLIAY----DTTDERVRYWCPACQ 254 T + D + ER YWCP CQ Sbjct 235 RTSLRVADQGDGSRERPTYWCPTCQ 259 >gi|297191673|ref|ZP_06909071.1| DNA glycosylase [Streptomyces pristinaespiralis ATCC 25486] gi|197721607|gb|EDY65515.1| DNA glycosylase [Streptomyces pristinaespiralis ATCC 25486] Length=274 Score = 216 bits (550), Expect = 3e-54, Method: Compositional matrix adjust. Identities = 128/266 (49%), Positives = 159/266 (60%), Gaps = 16/266 (6%) Query 1 MPEGDTVWHTAATLRRHLAGRTLTRCDIRVPRFAAVDLTGEVVDEVISRGKHLFIR-TGT 59 MPEGDTVW TA L LAG+ LTR D+RVPRFA DLTG V +V RGKHL R G Sbjct 8 MPEGDTVWLTAHRLHEALAGQVLTRSDLRVPRFATADLTGRTVLDVTPRGKHLLTRFEGG 67 Query 60 ASIHSHLQMDGSWRVGNRPVR----VDHRARIILEANQQEQAIRVVGVDLGLLEVIDRHN 115 ++HSHL M+GSWRV + R H+ R IL + A VG L ++E++ Sbjct 68 LTLHSHLGMEGSWRVFDAGARWSGGPSHQIRAILGS----AARTAVGYRLPVVELLRTAE 123 Query 116 DGAVVAHLGPDLLADDWDPQRAAANLIVAPDRPIAEALLDQRVLAGIGNVYCNELCFVSG 175 + V HLGPDLL DWDP RA ANL+ P RP+ EALLDQR LAGIGNVY +EL F++ Sbjct 124 EEEAVGHLGPDLLGPDWDPGRAVANLLADPLRPLGEALLDQRNLAGIGNVYKSELAFLAR 183 Query 176 VLPTAPVSAVAD--PRRLVTRARDMLWVNRFRWNRCTTGDTR-AGRRLWVYGRAGQGCRR 232 V P PV + P RLV A+ +L N+ ++R T R ++L+VYGR G+ C R Sbjct 184 VTPWLPVGELPPGIPERLVATAQRLLEANKRSFDRRTMTSGRNPSQKLYVYGRKGRPCPR 243 Query 233 CGTLIAY----DTTDERVRYWCPACQ 254 CGT + + ER YWCP CQ Sbjct 244 CGTPVRKADQGEAGRERPTYWCPRCQ 269 >gi|21224106|ref|NP_629885.1| DNA glycosylase [Streptomyces coelicolor A3(2)] gi|7531104|sp|O86820.3|Y5760_STRCO RecName: Full=Putative DNA glycosylase SCO5760; AltName: Full=Putative DNA-(apurinic or apyrimidinic site) lyase SCO5760; Short=Putative AP lyase SCO5760 gi|3294248|emb|CAA19861.1| DNA glycosylase [Streptomyces coelicolor A3(2)] Length=276 Score = 214 bits (546), Expect = 7e-54, Method: Compositional matrix adjust. Identities = 132/265 (50%), Positives = 158/265 (60%), Gaps = 17/265 (6%) Query 1 MPEGDTVWHTAATLRRHLAGRTLTRCDIRVPRFAAVDLTGEVVDEVISRGKHLFIRT-GT 59 MPEGDTVW A L LAGR LTR D RVPR+A VDLTG V +V RGKHL R G Sbjct 1 MPEGDTVWQAARRLHDALAGRVLTRSDFRVPRYATVDLTGRTVLDVTPRGKHLLTRVEGG 60 Query 60 ASIHSHLQMDGSWRVGNRPVRVD----HRARIILEANQQEQAIRVVGVDLGLLEVIDRHN 115 ++HSHL+MDGSW+V R H+ R+IL + VG L +L+++ Sbjct 61 LTVHSHLRMDGSWKVFAPGQRWSGGPAHQIRVILGTADRT----AVGYRLPVLDILRTAE 116 Query 116 DGAVVAHLGPDLLADDWDPQRAAANLIVAPDRPIAEALLDQRVLAGIGNVYCNELCFVSG 175 + V HLGPDLL DWDP+RA NL P R + EALLDQR LAGIGNVY +ELCF+ G Sbjct 117 EQRAVGHLGPDLLGPDWDPERALDNLRADPPRALGEALLDQRNLAGIGNVYKSELCFLLG 176 Query 176 VLPTAPVSAVADPR--RLVTRARDMLWVNRFRWNRCTTGDTRAGRRLWVYGRAGQGCRRC 233 V P PV + R RL T A+ +L NR R R TTG G+ L+VYGRA + C RC Sbjct 177 VTPWLPVGELPADRAARLPTLAKKLLEANRDRPVRRTTG--LRGQDLFVYGRAPRPCLRC 234 Query 234 GTLIAY----DTTDERVRYWCPACQ 254 GT + D + ER YWCP CQ Sbjct 235 GTSVRVADQGDGSRERPTYWCPTCQ 259 >gi|289768704|ref|ZP_06528082.1| DNA glycosylase [Streptomyces lividans TK24] gi|289698903|gb|EFD66332.1| DNA glycosylase [Streptomyces lividans TK24] Length=276 Score = 213 bits (541), Expect = 3e-53, Method: Compositional matrix adjust. Identities = 131/265 (50%), Positives = 157/265 (60%), Gaps = 17/265 (6%) Query 1 MPEGDTVWHTAATLRRHLAGRTLTRCDIRVPRFAAVDLTGEVVDEVISRGKHLFIRT-GT 59 MPEGDTVW A L LAGR LTR D RVPR+A VDLTG V +V RGKHL R G Sbjct 1 MPEGDTVWQAARRLHDALAGRVLTRSDFRVPRYATVDLTGRTVLDVTPRGKHLLTRVEGG 60 Query 60 ASIHSHLQMDGSWRVGNRPVR----VDHRARIILEANQQEQAIRVVGVDLGLLEVIDRHN 115 ++HSHL+MDGSW+V R H+ R+IL + VG L +L+++ Sbjct 61 LTVHSHLRMDGSWKVFAPGQRWSGGPAHQIRVILGTADRT----AVGYRLPVLDILRTAE 116 Query 116 DGAVVAHLGPDLLADDWDPQRAAANLIVAPDRPIAEALLDQRVLAGIGNVYCNELCFVSG 175 + V HLGPDLL DWDP+RA NL P R + EALLDQR LAGIGNVY +ELCF+ G Sbjct 117 EQRAVGHLGPDLLGPDWDPERALDNLRADPPRALGEALLDQRNLAGIGNVYKSELCFLLG 176 Query 176 VLPTAPVSAVADPR--RLVTRARDMLWVNRFRWNRCTTGDTRAGRRLWVYGRAGQGCRRC 233 V P PV + R RL T A+ +L NR R TTG G+ L+VYGRA + C RC Sbjct 177 VTPWLPVGELPADRAARLPTLAKKLLEANRDHPVRRTTG--LRGQDLFVYGRAPRPCLRC 234 Query 234 GTLIAY----DTTDERVRYWCPACQ 254 GT + D + ER YWCP CQ Sbjct 235 GTSVRVADQGDGSRERPTYWCPTCQ 259 Lambda K H 0.325 0.139 0.451 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 374688414660 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40