BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv3300c Length=305 Score E Sequences producing significant alignments: (Bits) Value gi|15610436|ref|NP_217817.1| hypothetical protein Rv3300c [Mycob... 597 1e-168 gi|31794480|ref|NP_856973.1| hypothetical protein Mb3328c [Mycob... 595 2e-168 gi|340628282|ref|YP_004746734.1| hypothetical protein MCAN_33231... 595 3e-168 gi|15842891|ref|NP_337928.1| hypothetical protein MT3399 [Mycoba... 593 1e-167 gi|308232412|ref|ZP_07415966.2| hypothetical protein TMAG_02753 ... 582 3e-164 gi|298526776|ref|ZP_07014185.1| pseudouridine synthase [Mycobact... 580 8e-164 gi|308370221|ref|ZP_07420688.2| hypothetical protein TMBG_01995 ... 577 9e-163 gi|289755423|ref|ZP_06514801.1| conserved hypothetical protein [... 567 7e-160 gi|289759444|ref|ZP_06518822.1| conserved hypothetical protein [... 506 1e-141 gi|342861522|ref|ZP_08718169.1| hypothetical protein MCOL_21656 ... 441 7e-122 gi|183981253|ref|YP_001849544.1| pseudouridine synthase [Mycobac... 434 8e-120 gi|296168884|ref|ZP_06850555.1| RNA pseudouridine synthase [Myco... 430 2e-118 gi|118618124|ref|YP_906456.1| pseudouridine synthase [Mycobacter... 429 2e-118 gi|240171345|ref|ZP_04750004.1| pseudouridine synthase [Mycobact... 416 3e-114 gi|254820676|ref|ZP_05225677.1| RNA pseudouridine synthase famil... 404 1e-110 gi|118464649|ref|YP_883417.1| RNA pseudouridine synthase [Mycoba... 402 5e-110 gi|41409520|ref|NP_962356.1| hypothetical protein MAP3422c [Myco... 401 6e-110 gi|254776711|ref|ZP_05218227.1| RNA pseudouridine synthase famil... 401 8e-110 gi|336459612|gb|EGO38547.1| 23S RNA-specific pseudouridylate syn... 389 2e-106 gi|120402627|ref|YP_952456.1| pseudouridine synthase [Mycobacter... 385 4e-105 gi|333991760|ref|YP_004524374.1| pseudouridine synthase [Mycobac... 384 1e-104 gi|118473504|ref|YP_886109.1| RNA pseudouridine synthase [Mycoba... 374 8e-102 gi|145225398|ref|YP_001136076.1| pseudouridine synthase [Mycobac... 363 1e-98 gi|315445746|ref|YP_004078625.1| 23S RNA-specific pseudouridylat... 359 3e-97 gi|126433880|ref|YP_001069571.1| pseudouridine synthase [Mycobac... 347 1e-93 gi|108798222|ref|YP_638419.1| pseudouridine synthase [Mycobacter... 344 1e-92 gi|169630733|ref|YP_001704382.1| pseudouridine synthase [Mycobac... 308 6e-82 gi|302526188|ref|ZP_07278530.1| ribosomal pseudouridine synthase... 286 2e-75 gi|134099890|ref|YP_001105551.1| ribosomal pseudouridine synthas... 283 2e-74 gi|325674660|ref|ZP_08154347.1| RNA pseudouridine synthase [Rhod... 280 2e-73 gi|312138349|ref|YP_004005685.1| tRNA-pseudouridine synthase i [... 280 2e-73 gi|111021862|ref|YP_704834.1| pseudouridylate synthase [Rhodococ... 275 8e-72 gi|54022716|ref|YP_116958.1| putative RNA pseudouridylate syntha... 274 1e-71 gi|226308249|ref|YP_002768209.1| pseudouridine synthase [Rhodoco... 274 2e-71 gi|302550275|ref|ZP_07302617.1| ribosomal pseudouridine synthase... 273 2e-71 gi|229488989|ref|ZP_04382855.1| pseudouridylate synthase [Rhodoc... 273 2e-71 gi|111017875|ref|YP_700847.1| pseudouridylate synthase [Rhodococ... 272 4e-71 gi|226364380|ref|YP_002782162.1| pseudouridine synthase [Rhodoco... 272 5e-71 gi|291440659|ref|ZP_06580049.1| ribosomal pseudouridine synthase... 271 7e-71 gi|269796147|ref|YP_003315602.1| 23S RNA-specific pseudouridylat... 271 1e-70 gi|300785329|ref|YP_003765620.1| RNA pseudouridylate synthase [A... 270 1e-70 gi|226360008|ref|YP_002777786.1| pseudouridine synthase [Rhodoco... 269 4e-70 gi|294628458|ref|ZP_06707018.1| RNA pseudouridylate synthase [St... 268 1e-69 gi|343926401|ref|ZP_08765906.1| putative pseudouridine synthase ... 267 2e-69 gi|258650803|ref|YP_003199959.1| pseudouridine synthase [Nakamur... 265 7e-69 gi|291450450|ref|ZP_06589840.1| ribosomal pseudouridine synthase... 265 9e-69 gi|331697825|ref|YP_004334064.1| pseudouridine synthase [Pseudon... 262 4e-68 gi|302561569|ref|ZP_07313911.1| pseudouridylate synthase [Strept... 262 5e-68 gi|297195328|ref|ZP_06912726.1| ribosomal pseudouridine synthase... 262 5e-68 gi|291443564|ref|ZP_06582954.1| ribosomal pseudouridine synthase... 261 1e-67 >gi|15610436|ref|NP_217817.1| hypothetical protein Rv3300c [Mycobacterium tuberculosis H37Rv] gi|121639189|ref|YP_979413.1| hypothetical protein BCG_3329c [Mycobacterium bovis BCG str. Pasteur 1173P2] gi|121639223|ref|YP_979447.1| hypothetical protein BCG_3365c [Mycobacterium bovis BCG str. Pasteur 1173P2] 48 more sequence titles Length=305 Score = 597 bits (1538), Expect = 1e-168, Method: Compositional matrix adjust. Identities = 304/305 (99%), Positives = 305/305 (100%), Gaps = 0/305 (0%) Query 1 VALRPEDRLLSVHDVLGPVRVRLLGGSVLAELTARFGVAARAKVLAGEVVDDDGAVVDSG 60 +ALRPEDRLLSVHDVLGPVRVRLLGGSVLAELTARFGVAARAKVLAGEVVDDDGAVVDSG Sbjct 1 MALRPEDRLLSVHDVLGPVRVRLLGGSVLAELTARFGVAARAKVLAGEVVDDDGAVVDSG 60 Query 61 TVLPPGSVVHLYRDLPDEVPVPFDVPVLHQDADIVVVDKPHFLATMPRGRHVAQTALVRL 120 TVLPPGSVVHLYRDLPDEVPVPFDVPVLHQDADIVVVDKPHFLATMPRGRHVAQTALVRL Sbjct 61 TVLPPGSVVHLYRDLPDEVPVPFDVPVLHQDADIVVVDKPHFLATMPRGRHVAQTALVRL 120 Query 121 RRELGLPELSPAHRLDRLTAGVLLFTTRREVRGSYQTMFARGLVRKTYLARAPVAPGLAL 180 RRELGLPELSPAHRLDRLTAGVLLFTTRREVRGSYQTMFARGLVRKTYLARAPVAPGLAL Sbjct 121 RRELGLPELSPAHRLDRLTAGVLLFTTRREVRGSYQTMFARGLVRKTYLARAPVAPGLAL 180 Query 181 PRLVRSRIVKRRGHLQAVCEPGVPNAETLVERIARDGLYRLTPTTGRTHQLRVHMAALGI 240 PRLVRSRIVKRRGHLQAVCEPGVPNAETLVERIARDGLYRLTPTTGRTHQLRVHMAALGI Sbjct 181 PRLVRSRIVKRRGHLQAVCEPGVPNAETLVERIARDGLYRLTPTTGRTHQLRVHMAALGI 240 Query 241 PIMGDPLYPNVISVAAHDFSTPLQLLAQRIEFDDPLTGSHREFASTRTLTGATLPTWSAA 300 PIMGDPLYPNVISVAAHDFSTPLQLLAQRIEFDDPLTGSHREFASTRTLTGATLPTWSAA Sbjct 241 PIMGDPLYPNVISVAAHDFSTPLQLLAQRIEFDDPLTGSHREFASTRTLTGATLPTWSAA 300 Query 301 ADCRP 305 ADCRP Sbjct 301 ADCRP 305 >gi|31794480|ref|NP_856973.1| hypothetical protein Mb3328c [Mycobacterium bovis AF2122/97] gi|31620076|emb|CAD95420.1| CONSERVED HYPOTHETICAL PROTEIN [Mycobacterium bovis AF2122/97] Length=305 Score = 595 bits (1535), Expect = 2e-168, Method: Compositional matrix adjust. Identities = 303/305 (99%), Positives = 305/305 (100%), Gaps = 0/305 (0%) Query 1 VALRPEDRLLSVHDVLGPVRVRLLGGSVLAELTARFGVAARAKVLAGEVVDDDGAVVDSG 60 +ALRPEDRLLSVHDVLGPVRVRLLGGSVLAELTARFGVAARAKVLAGEVVD+DGAVVDSG Sbjct 1 MALRPEDRLLSVHDVLGPVRVRLLGGSVLAELTARFGVAARAKVLAGEVVDNDGAVVDSG 60 Query 61 TVLPPGSVVHLYRDLPDEVPVPFDVPVLHQDADIVVVDKPHFLATMPRGRHVAQTALVRL 120 TVLPPGSVVHLYRDLPDEVPVPFDVPVLHQDADIVVVDKPHFLATMPRGRHVAQTALVRL Sbjct 61 TVLPPGSVVHLYRDLPDEVPVPFDVPVLHQDADIVVVDKPHFLATMPRGRHVAQTALVRL 120 Query 121 RRELGLPELSPAHRLDRLTAGVLLFTTRREVRGSYQTMFARGLVRKTYLARAPVAPGLAL 180 RRELGLPELSPAHRLDRLTAGVLLFTTRREVRGSYQTMFARGLVRKTYLARAPVAPGLAL Sbjct 121 RRELGLPELSPAHRLDRLTAGVLLFTTRREVRGSYQTMFARGLVRKTYLARAPVAPGLAL 180 Query 181 PRLVRSRIVKRRGHLQAVCEPGVPNAETLVERIARDGLYRLTPTTGRTHQLRVHMAALGI 240 PRLVRSRIVKRRGHLQAVCEPGVPNAETLVERIARDGLYRLTPTTGRTHQLRVHMAALGI Sbjct 181 PRLVRSRIVKRRGHLQAVCEPGVPNAETLVERIARDGLYRLTPTTGRTHQLRVHMAALGI 240 Query 241 PIMGDPLYPNVISVAAHDFSTPLQLLAQRIEFDDPLTGSHREFASTRTLTGATLPTWSAA 300 PIMGDPLYPNVISVAAHDFSTPLQLLAQRIEFDDPLTGSHREFASTRTLTGATLPTWSAA Sbjct 241 PIMGDPLYPNVISVAAHDFSTPLQLLAQRIEFDDPLTGSHREFASTRTLTGATLPTWSAA 300 Query 301 ADCRP 305 ADCRP Sbjct 301 ADCRP 305 >gi|340628282|ref|YP_004746734.1| hypothetical protein MCAN_33231 [Mycobacterium canettii CIPT 140010059] gi|340006472|emb|CCC45654.1| conserved hypothetical protein [Mycobacterium canettii CIPT 140010059] Length=305 Score = 595 bits (1533), Expect = 3e-168, Method: Compositional matrix adjust. Identities = 303/305 (99%), Positives = 305/305 (100%), Gaps = 0/305 (0%) Query 1 VALRPEDRLLSVHDVLGPVRVRLLGGSVLAELTARFGVAARAKVLAGEVVDDDGAVVDSG 60 +ALRPEDRLLSVHDVLGPVRVRLLGGSVLAELTARFGVAARAKVLAGEVVDDDGAVVDSG Sbjct 1 MALRPEDRLLSVHDVLGPVRVRLLGGSVLAELTARFGVAARAKVLAGEVVDDDGAVVDSG 60 Query 61 TVLPPGSVVHLYRDLPDEVPVPFDVPVLHQDADIVVVDKPHFLATMPRGRHVAQTALVRL 120 TVLPPGSVVHLYRDLPDEVPVPFDVPVLHQDADIVVVDKPHFLATMPRGRHVAQTALVRL Sbjct 61 TVLPPGSVVHLYRDLPDEVPVPFDVPVLHQDADIVVVDKPHFLATMPRGRHVAQTALVRL 120 Query 121 RRELGLPELSPAHRLDRLTAGVLLFTTRREVRGSYQTMFARGLVRKTYLARAPVAPGLAL 180 RRELGLPELSPAHRLDRLTAGVLLFTTRREVRGSYQTMFARGLVRKTYLARAPVAPGLAL Sbjct 121 RRELGLPELSPAHRLDRLTAGVLLFTTRREVRGSYQTMFARGLVRKTYLARAPVAPGLAL 180 Query 181 PRLVRSRIVKRRGHLQAVCEPGVPNAETLVERIARDGLYRLTPTTGRTHQLRVHMAALGI 240 PRLVRSRIVKRRGHLQAVCEPGVPNAETLVERIARDGLYRLTPTTGRTHQLRVHMAALGI Sbjct 181 PRLVRSRIVKRRGHLQAVCEPGVPNAETLVERIARDGLYRLTPTTGRTHQLRVHMAALGI 240 Query 241 PIMGDPLYPNVISVAAHDFSTPLQLLAQRIEFDDPLTGSHREFASTRTLTGATLPTWSAA 300 PI+GDPLYPNVISVAAHDFSTPLQLLAQRIEFDDPLTGSHREFASTRTLTGATLPTWSAA Sbjct 241 PIIGDPLYPNVISVAAHDFSTPLQLLAQRIEFDDPLTGSHREFASTRTLTGATLPTWSAA 300 Query 301 ADCRP 305 ADCRP Sbjct 301 ADCRP 305 >gi|15842891|ref|NP_337928.1| hypothetical protein MT3399 [Mycobacterium tuberculosis CDC1551] gi|13883223|gb|AAK47742.1| RNA pseudouridylate synthase family protein [Mycobacterium tuberculosis CDC1551] gi|323718169|gb|EGB27351.1| hypothetical protein TMMG_02448 [Mycobacterium tuberculosis CDC1551A] Length=305 Score = 593 bits (1529), Expect = 1e-167, Method: Compositional matrix adjust. Identities = 303/305 (99%), Positives = 304/305 (99%), Gaps = 0/305 (0%) Query 1 VALRPEDRLLSVHDVLGPVRVRLLGGSVLAELTARFGVAARAKVLAGEVVDDDGAVVDSG 60 +ALRPEDRLLSVHDVLGPVRVRLLGGSVLAELTARFGVAARAKVLAGEVVDDDGAVVDSG Sbjct 1 MALRPEDRLLSVHDVLGPVRVRLLGGSVLAELTARFGVAARAKVLAGEVVDDDGAVVDSG 60 Query 61 TVLPPGSVVHLYRDLPDEVPVPFDVPVLHQDADIVVVDKPHFLATMPRGRHVAQTALVRL 120 TVLPPGSVVHLYRDLPDEVPVPFDVPVLHQDADIVVVDKPHFLATMPRGRHVAQTALVRL Sbjct 61 TVLPPGSVVHLYRDLPDEVPVPFDVPVLHQDADIVVVDKPHFLATMPRGRHVAQTALVRL 120 Query 121 RRELGLPELSPAHRLDRLTAGVLLFTTRREVRGSYQTMFARGLVRKTYLARAPVAPGLAL 180 RRELGLPELSPAHRLDRLTAGVLLFTTRREVRGSYQTMFARGLVRKTYLARAPVAPGLAL Sbjct 121 RRELGLPELSPAHRLDRLTAGVLLFTTRREVRGSYQTMFARGLVRKTYLARAPVAPGLAL 180 Query 181 PRLVRSRIVKRRGHLQAVCEPGVPNAETLVERIARDGLYRLTPTTGRTHQLRVHMAALGI 240 PRLVRSRIVKRRGHLQAVCEPGVPNAETLVERIARDGLYRLTPTTGRTHQLRVHMAALGI Sbjct 181 PRLVRSRIVKRRGHLQAVCEPGVPNAETLVERIARDGLYRLTPTTGRTHQLRVHMAALGI 240 Query 241 PIMGDPLYPNVISVAAHDFSTPLQLLAQRIEFDDPLTGSHREFASTRTLTGATLPTWSAA 300 PIMGDPLYPNVISVAAH FSTPLQLLAQRIEFDDPLTGSHREFASTRTLTGATLPTWSAA Sbjct 241 PIMGDPLYPNVISVAAHYFSTPLQLLAQRIEFDDPLTGSHREFASTRTLTGATLPTWSAA 300 Query 301 ADCRP 305 ADCRP Sbjct 301 ADCRP 305 >gi|308232412|ref|ZP_07415966.2| hypothetical protein TMAG_02753 [Mycobacterium tuberculosis SUMu001] gi|308380643|ref|ZP_07490629.2| hypothetical protein TMKG_02560 [Mycobacterium tuberculosis SUMu011] gi|308406115|ref|ZP_07495174.2| hypothetical protein TMLG_02074 [Mycobacterium tuberculosis SUMu012] gi|308214050|gb|EFO73449.1| hypothetical protein TMAG_02753 [Mycobacterium tuberculosis SUMu001] gi|308360844|gb|EFP49695.1| hypothetical protein TMKG_02560 [Mycobacterium tuberculosis SUMu011] gi|308364529|gb|EFP53380.1| hypothetical protein TMLG_02074 [Mycobacterium tuberculosis SUMu012] Length=297 Score = 582 bits (1499), Expect = 3e-164, Method: Compositional matrix adjust. Identities = 296/297 (99%), Positives = 297/297 (100%), Gaps = 0/297 (0%) Query 9 LLSVHDVLGPVRVRLLGGSVLAELTARFGVAARAKVLAGEVVDDDGAVVDSGTVLPPGSV 68 +LSVHDVLGPVRVRLLGGSVLAELTARFGVAARAKVLAGEVVDDDGAVVDSGTVLPPGSV Sbjct 1 MLSVHDVLGPVRVRLLGGSVLAELTARFGVAARAKVLAGEVVDDDGAVVDSGTVLPPGSV 60 Query 69 VHLYRDLPDEVPVPFDVPVLHQDADIVVVDKPHFLATMPRGRHVAQTALVRLRRELGLPE 128 VHLYRDLPDEVPVPFDVPVLHQDADIVVVDKPHFLATMPRGRHVAQTALVRLRRELGLPE Sbjct 61 VHLYRDLPDEVPVPFDVPVLHQDADIVVVDKPHFLATMPRGRHVAQTALVRLRRELGLPE 120 Query 129 LSPAHRLDRLTAGVLLFTTRREVRGSYQTMFARGLVRKTYLARAPVAPGLALPRLVRSRI 188 LSPAHRLDRLTAGVLLFTTRREVRGSYQTMFARGLVRKTYLARAPVAPGLALPRLVRSRI Sbjct 121 LSPAHRLDRLTAGVLLFTTRREVRGSYQTMFARGLVRKTYLARAPVAPGLALPRLVRSRI 180 Query 189 VKRRGHLQAVCEPGVPNAETLVERIARDGLYRLTPTTGRTHQLRVHMAALGIPIMGDPLY 248 VKRRGHLQAVCEPGVPNAETLVERIARDGLYRLTPTTGRTHQLRVHMAALGIPIMGDPLY Sbjct 181 VKRRGHLQAVCEPGVPNAETLVERIARDGLYRLTPTTGRTHQLRVHMAALGIPIMGDPLY 240 Query 249 PNVISVAAHDFSTPLQLLAQRIEFDDPLTGSHREFASTRTLTGATLPTWSAAADCRP 305 PNVISVAAHDFSTPLQLLAQRIEFDDPLTGSHREFASTRTLTGATLPTWSAAADCRP Sbjct 241 PNVISVAAHDFSTPLQLLAQRIEFDDPLTGSHREFASTRTLTGATLPTWSAAADCRP 297 >gi|298526776|ref|ZP_07014185.1| pseudouridine synthase [Mycobacterium tuberculosis 94_M4241A] gi|298496570|gb|EFI31864.1| pseudouridine synthase [Mycobacterium tuberculosis 94_M4241A] Length=297 Score = 580 bits (1496), Expect = 8e-164, Method: Compositional matrix adjust. Identities = 295/297 (99%), Positives = 296/297 (99%), Gaps = 0/297 (0%) Query 9 LLSVHDVLGPVRVRLLGGSVLAELTARFGVAARAKVLAGEVVDDDGAVVDSGTVLPPGSV 68 +LSVHDVLGPVRVRLLGGSVLAELTARFGVAARAKVLAGEVVDDDGAVVDSGTVLPPGSV Sbjct 1 MLSVHDVLGPVRVRLLGGSVLAELTARFGVAARAKVLAGEVVDDDGAVVDSGTVLPPGSV 60 Query 69 VHLYRDLPDEVPVPFDVPVLHQDADIVVVDKPHFLATMPRGRHVAQTALVRLRRELGLPE 128 VHLYRDLPDEVPVPFDVPVLHQDADIVVVDKPHFLATMPRGRHVAQTALVRLRRELGLPE Sbjct 61 VHLYRDLPDEVPVPFDVPVLHQDADIVVVDKPHFLATMPRGRHVAQTALVRLRRELGLPE 120 Query 129 LSPAHRLDRLTAGVLLFTTRREVRGSYQTMFARGLVRKTYLARAPVAPGLALPRLVRSRI 188 LSPAHRLDRLTAGVLLFTTRREVRGSYQTMFARGLVRKTYLARAPVAPGLALPRLVRSRI Sbjct 121 LSPAHRLDRLTAGVLLFTTRREVRGSYQTMFARGLVRKTYLARAPVAPGLALPRLVRSRI 180 Query 189 VKRRGHLQAVCEPGVPNAETLVERIARDGLYRLTPTTGRTHQLRVHMAALGIPIMGDPLY 248 VKRRGHLQAVCEPGVPNAETLVERIARDGLYRLTPTTGRTHQLRVHMAALGIPIMGDPLY Sbjct 181 VKRRGHLQAVCEPGVPNAETLVERIARDGLYRLTPTTGRTHQLRVHMAALGIPIMGDPLY 240 Query 249 PNVISVAAHDFSTPLQLLAQRIEFDDPLTGSHREFASTRTLTGATLPTWSAAADCRP 305 PNVISVAAHDFSTPLQLLAQRIEFDDPLTGSHREFASTR LTGATLPTWSAAADCRP Sbjct 241 PNVISVAAHDFSTPLQLLAQRIEFDDPLTGSHREFASTRKLTGATLPTWSAAADCRP 297 >gi|308370221|ref|ZP_07420688.2| hypothetical protein TMBG_01995 [Mycobacterium tuberculosis SUMu002] gi|308371305|ref|ZP_07424495.2| hypothetical protein TMCG_01723 [Mycobacterium tuberculosis SUMu003] gi|308372495|ref|ZP_07428863.2| hypothetical protein TMDG_02135 [Mycobacterium tuberculosis SUMu004] 17 more sequence titles Length=294 Score = 577 bits (1487), Expect = 9e-163, Method: Compositional matrix adjust. Identities = 293/294 (99%), Positives = 294/294 (100%), Gaps = 0/294 (0%) Query 12 VHDVLGPVRVRLLGGSVLAELTARFGVAARAKVLAGEVVDDDGAVVDSGTVLPPGSVVHL 71 +HDVLGPVRVRLLGGSVLAELTARFGVAARAKVLAGEVVDDDGAVVDSGTVLPPGSVVHL Sbjct 1 MHDVLGPVRVRLLGGSVLAELTARFGVAARAKVLAGEVVDDDGAVVDSGTVLPPGSVVHL 60 Query 72 YRDLPDEVPVPFDVPVLHQDADIVVVDKPHFLATMPRGRHVAQTALVRLRRELGLPELSP 131 YRDLPDEVPVPFDVPVLHQDADIVVVDKPHFLATMPRGRHVAQTALVRLRRELGLPELSP Sbjct 61 YRDLPDEVPVPFDVPVLHQDADIVVVDKPHFLATMPRGRHVAQTALVRLRRELGLPELSP 120 Query 132 AHRLDRLTAGVLLFTTRREVRGSYQTMFARGLVRKTYLARAPVAPGLALPRLVRSRIVKR 191 AHRLDRLTAGVLLFTTRREVRGSYQTMFARGLVRKTYLARAPVAPGLALPRLVRSRIVKR Sbjct 121 AHRLDRLTAGVLLFTTRREVRGSYQTMFARGLVRKTYLARAPVAPGLALPRLVRSRIVKR 180 Query 192 RGHLQAVCEPGVPNAETLVERIARDGLYRLTPTTGRTHQLRVHMAALGIPIMGDPLYPNV 251 RGHLQAVCEPGVPNAETLVERIARDGLYRLTPTTGRTHQLRVHMAALGIPIMGDPLYPNV Sbjct 181 RGHLQAVCEPGVPNAETLVERIARDGLYRLTPTTGRTHQLRVHMAALGIPIMGDPLYPNV 240 Query 252 ISVAAHDFSTPLQLLAQRIEFDDPLTGSHREFASTRTLTGATLPTWSAAADCRP 305 ISVAAHDFSTPLQLLAQRIEFDDPLTGSHREFASTRTLTGATLPTWSAAADCRP Sbjct 241 ISVAAHDFSTPLQLLAQRIEFDDPLTGSHREFASTRTLTGATLPTWSAAADCRP 294 >gi|289755423|ref|ZP_06514801.1| conserved hypothetical protein [Mycobacterium tuberculosis EAS054] gi|289696010|gb|EFD63439.1| conserved hypothetical protein [Mycobacterium tuberculosis EAS054] Length=304 Score = 567 bits (1462), Expect = 7e-160, Method: Compositional matrix adjust. Identities = 303/305 (99%), Positives = 304/305 (99%), Gaps = 1/305 (0%) Query 1 VALRPEDRLLSVHDVLGPVRVRLLGGSVLAELTARFGVAARAKVLAGEVVDDDGAVVDSG 60 +ALRPEDRLLSVHDVLGPVRVRLLGGSVLAELTARFGVAARAKVLAGEVVDDDGAVVDSG Sbjct 1 MALRPEDRLLSVHDVLGPVRVRLLGGSVLAELTARFGVAARAKVLAGEVVDDDGAVVDSG 60 Query 61 TVLPPGSVVHLYRDLPDEVPVPFDVPVLHQDADIVVVDKPHFLATMPRGRHVAQTALVRL 120 TVLPPGSVVHLYRDLPDEVPVPFDVPVLHQDADIVV DKPHFLATMPRGRHVAQTALVRL Sbjct 61 TVLPPGSVVHLYRDLPDEVPVPFDVPVLHQDADIVV-DKPHFLATMPRGRHVAQTALVRL 119 Query 121 RRELGLPELSPAHRLDRLTAGVLLFTTRREVRGSYQTMFARGLVRKTYLARAPVAPGLAL 180 RRELGLPELSPAHRLDRLTAGVLLFTTRREVRGSYQTMFARGLVRKTYLARAPVAPGLAL Sbjct 120 RRELGLPELSPAHRLDRLTAGVLLFTTRREVRGSYQTMFARGLVRKTYLARAPVAPGLAL 179 Query 181 PRLVRSRIVKRRGHLQAVCEPGVPNAETLVERIARDGLYRLTPTTGRTHQLRVHMAALGI 240 PRLVRSRIVKRRGHLQAVCEPGVPNAETLVERIARDGLYRLTPTTGRTHQLRVHMAALGI Sbjct 180 PRLVRSRIVKRRGHLQAVCEPGVPNAETLVERIARDGLYRLTPTTGRTHQLRVHMAALGI 239 Query 241 PIMGDPLYPNVISVAAHDFSTPLQLLAQRIEFDDPLTGSHREFASTRTLTGATLPTWSAA 300 PIMGDPLYPNVISVAAHDFSTPLQLLAQRIEFDDPLTGSHREFASTRTLTGATLPTWSAA Sbjct 240 PIMGDPLYPNVISVAAHDFSTPLQLLAQRIEFDDPLTGSHREFASTRTLTGATLPTWSAA 299 Query 301 ADCRP 305 ADCRP Sbjct 300 ADCRP 304 >gi|289759444|ref|ZP_06518822.1| conserved hypothetical protein [Mycobacterium tuberculosis T85] gi|289715008|gb|EFD79020.1| conserved hypothetical protein [Mycobacterium tuberculosis T85] Length=306 Score = 506 bits (1304), Expect = 1e-141, Method: Compositional matrix adjust. Identities = 278/311 (90%), Positives = 285/311 (92%), Gaps = 11/311 (3%) Query 1 VALRPEDRLLSVHDVLGPVRVRLLGGSVLAELTARFGVAARAKVLAGEVVDDDGAVVDSG 60 +ALRPEDRLLSVHDVLGPVRVRLLGGSVLAELTARFGVAARAKVLAGEVVDDDGAVVDSG Sbjct 1 MALRPEDRLLSVHDVLGPVRVRLLGGSVLAELTARFGVAARAKVLAGEVVDDDGAVVDSG 60 Query 61 TVLPPGSVVHLYRDLPDEVPVPFDVPVLHQDADIVVVDKPHFLATMPRGRHVAQTALVRL 120 TVLPPGSVVHLYRDLPDEVPVPFDVPVLHQDADIVVVDKPHFLATMPRGRHVAQTALVRL Sbjct 61 TVLPPGSVVHLYRDLPDEVPVPFDVPVLHQDADIVVVDKPHFLATMPRGRHVAQTALVRL 120 Query 121 RRELGLPELSPAHRLDRLTAGVLLFTTRREVRGSYQTMFARGLVRKTYLARAPVAPGLAL 180 RRELGLPELSPAHRLDRLTAGVLLFTTRREVRGSYQTMFARGLVRKTYLARAPVAPGLAL Sbjct 121 RRELGLPELSPAHRLDRLTAGVLLFTTRREVRGSYQTMFARGLVRKTYLARAPVAPGLAL 180 Query 181 PRLVRSRIVKRRGHLQAVCEPGVPN------AETLVERIARDGLYRLTPTTGRTHQLRVH 234 PRLVRSRIVKRRGHLQAVCEPGVPN A++ ++ D +R PT+ Sbjct 181 PRLVRSRIVKRRGHLQAVCEPGVPNAGDAGGADSARRSVSADTDHRGAPTS-----CECT 235 Query 235 MAALGIPIMGDPLYPNVISVAAHDFSTPLQLLAQRIEFDDPLTGSHREFASTRTLTGATL 294 ALGIPIMGDPLYPNVISVAAHDFSTPLQLLAQRIEFDDPLTGSHREFASTRTLTGATL Sbjct 236 WRALGIPIMGDPLYPNVISVAAHDFSTPLQLLAQRIEFDDPLTGSHREFASTRTLTGATL 295 Query 295 PTWSAAADCRP 305 PTWSAAADCRP Sbjct 296 PTWSAAADCRP 306 >gi|342861522|ref|ZP_08718169.1| hypothetical protein MCOL_21656 [Mycobacterium colombiense CECT 3035] gi|342131011|gb|EGT84300.1| hypothetical protein MCOL_21656 [Mycobacterium colombiense CECT 3035] Length=279 Score = 441 bits (1134), Expect = 7e-122, Method: Compositional matrix adjust. Identities = 224/276 (82%), Positives = 245/276 (89%), Gaps = 0/276 (0%) Query 12 VHDVLGPVRVRLLGGSVLAELTARFGVAARAKVLAGEVVDDDGAVVDSGTVLPPGSVVHL 71 + D LGP R+RL GG VLAELTARFG AARAKVLAGEVV DGAV+D+GTVLP G+ V+L Sbjct 1 MRDGLGPARLRLRGGPVLAELTARFGAAARAKVLAGEVVGADGAVIDAGTVLPAGASVYL 60 Query 72 YRDLPDEVPVPFDVPVLHQDADIVVVDKPHFLATMPRGRHVAQTALVRLRRELGLPELSP 131 YR+LPDEVPVPFD+PVLH+DADIV+VDKPHFLATMPRGRHVAQTALVRLRRELGLPELSP Sbjct 61 YRELPDEVPVPFDIPVLHRDADIVIVDKPHFLATMPRGRHVAQTALVRLRRELGLPELSP 120 Query 132 AHRLDRLTAGVLLFTTRREVRGSYQTMFARGLVRKTYLARAPVAPGLALPRLVRSRIVKR 191 AHRLDRLTAGVLLFT RREVRG+YQT+FARGLV KTYLARA V P L LPR+VRSRI+KR Sbjct 121 AHRLDRLTAGVLLFTARREVRGAYQTLFARGLVAKTYLARAGVDPELELPRVVRSRIIKR 180 Query 192 RGHLQAVCEPGVPNAETLVERIARDGLYRLTPTTGRTHQLRVHMAALGIPIMGDPLYPNV 251 RGHLQAVCEPG PNAET VE I+ DGLYRLTP TGRTHQLR+HMA+LG+PI GDPLYPN+ Sbjct 181 RGHLQAVCEPGAPNAETRVELISADGLYRLTPRTGRTHQLRLHMASLGVPIDGDPLYPNI 240 Query 252 ISVAAHDFSTPLQLLAQRIEFDDPLTGSHREFASTR 287 I VA DFS PL+LLAQRI F DPLTG+ REF S R Sbjct 241 IDVAPDDFSAPLRLLAQRIAFTDPLTGARREFVSRR 276 >gi|183981253|ref|YP_001849544.1| pseudouridine synthase [Mycobacterium marinum M] gi|183174579|gb|ACC39689.1| pseudouridine synthase [Mycobacterium marinum M] Length=288 Score = 434 bits (1116), Expect = 8e-120, Method: Compositional matrix adjust. Identities = 223/283 (79%), Positives = 243/283 (86%), Gaps = 3/283 (1%) Query 10 LSVHDVLGPVRVRLLGGSVLAELTARFGVAARAKVLAGEVVDDDGAVVDSGTVLPPGSVV 69 L V D LGP RVRL GG VLAEL+ RFG AARAKVLAGEVVD GA+VD+ TV PGS V Sbjct 6 LRVRDALGPARVRLHGGPVLAELSERFGAAARAKVLAGEVVDAAGAIVDTATVAEPGSYV 65 Query 70 HLYRDLPDEVPVPFDVPVLHQDADIVVVDKPHFLATMPRGRHVAQTALVRLRRELGLPEL 129 +LYRDLP+EVPVPF++PVLHQD DIVV DKPHFLATMPRGRHVAQTALVRLR ELGLPEL Sbjct 66 YLYRDLPEEVPVPFEMPVLHQDEDIVVADKPHFLATMPRGRHVAQTALVRLRCELGLPEL 125 Query 130 SPAHRLDRLTAGVLLFTTRREVRGSYQTMFARGLVRKTYLARAPVAPGLALPRLVRSRIV 189 SPAHRLDRLTAGVLLFTTRRE+RG YQT+FARG VRKTYLARA V LA PR++RSRIV Sbjct 126 SPAHRLDRLTAGVLLFTTRRELRGRYQTLFARGAVRKTYLARAAVDADLAFPRVIRSRIV 185 Query 190 KRRGHLQAVCEPGVPNAETLVERIARDGLYRLTPTTGRTHQLRVHMAALGIPIMGDPLYP 249 KRRGHLQAVCEPG PNAETLVE I+ +GLYRLTP TGRTHQLRVHMA+LG+PI GDPLYP Sbjct 186 KRRGHLQAVCEPGEPNAETLVELISPEGLYRLTPRTGRTHQLRVHMASLGLPIFGDPLYP 245 Query 250 NVISVAAH---DFSTPLQLLAQRIEFDDPLTGSHREFASTRTL 289 NVI + H DFS+PL LLAQRIEF+DPL+GS REF S R + Sbjct 246 NVIPESPHDLSDFSSPLSLLAQRIEFEDPLSGSRREFVSPREI 288 >gi|296168884|ref|ZP_06850555.1| RNA pseudouridine synthase [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295896450|gb|EFG76101.1| RNA pseudouridine synthase [Mycobacterium parascrofulaceum ATCC BAA-614] Length=279 Score = 430 bits (1105), Expect = 2e-118, Method: Compositional matrix adjust. Identities = 220/278 (80%), Positives = 241/278 (87%), Gaps = 0/278 (0%) Query 12 VHDVLGPVRVRLLGGSVLAELTARFGVAARAKVLAGEVVDDDGAVVDSGTVLPPGSVVHL 71 + D LGP RVRL GG VLAELT RFG +AR+KVLAGEVVD DG+ VD T LP G+ V+L Sbjct 1 MRDGLGPARVRLRGGPVLAELTGRFGASARSKVLAGEVVDADGSPVDEATALPAGASVYL 60 Query 72 YRDLPDEVPVPFDVPVLHQDADIVVVDKPHFLATMPRGRHVAQTALVRLRRELGLPELSP 131 YR+LP+EVPVPFD+PVLH+DADIVVVDKPHFLATMPRGRHVAQTALVRLRRELGLPELSP Sbjct 61 YRELPEEVPVPFDIPVLHRDADIVVVDKPHFLATMPRGRHVAQTALVRLRRELGLPELSP 120 Query 132 AHRLDRLTAGVLLFTTRREVRGSYQTMFARGLVRKTYLARAPVAPGLALPRLVRSRIVKR 191 AHRLDRLTAGVLLFT RREVRG+YQT+F+RGLVRKTYLARA V P L LPR+VRSRI+KR Sbjct 121 AHRLDRLTAGVLLFTARREVRGAYQTLFSRGLVRKTYLARAAVDPALVLPRVVRSRIIKR 180 Query 192 RGHLQAVCEPGVPNAETLVERIARDGLYRLTPTTGRTHQLRVHMAALGIPIMGDPLYPNV 251 RG LQA CEPG PNAETLVE + DGLYRLTP TGRTHQLRVHMAALG+PI GDPLYP++ Sbjct 181 RGVLQAGCEPGTPNAETLVELASPDGLYRLTPRTGRTHQLRVHMAALGVPIDGDPLYPDI 240 Query 252 ISVAAHDFSTPLQLLAQRIEFDDPLTGSHREFASTRTL 289 + V DFSTPL LLA+RI FDDPLTG REF S RTL Sbjct 241 VDVPPDDFSTPLGLLARRIAFDDPLTGERREFVSRRTL 278 >gi|118618124|ref|YP_906456.1| pseudouridine synthase [Mycobacterium ulcerans Agy99] gi|118570234|gb|ABL04985.1| pseudouridine synthase [Mycobacterium ulcerans Agy99] Length=288 Score = 429 bits (1104), Expect = 2e-118, Method: Compositional matrix adjust. Identities = 222/283 (79%), Positives = 242/283 (86%), Gaps = 3/283 (1%) Query 10 LSVHDVLGPVRVRLLGGSVLAELTARFGVAARAKVLAGEVVDDDGAVVDSGTVLPPGSVV 69 L V D LGP RVRL GG VLAEL+ RFG AARAKVLAGEVVD GA+V + TV PGS V Sbjct 6 LRVRDALGPARVRLHGGPVLAELSERFGAAARAKVLAGEVVDAAGAIVGTATVAGPGSHV 65 Query 70 HLYRDLPDEVPVPFDVPVLHQDADIVVVDKPHFLATMPRGRHVAQTALVRLRRELGLPEL 129 +LYRDLP+EVPVPF++PVLHQD DIVV DKPHFLATMPRGRHVAQTALVRLR ELGLPEL Sbjct 66 YLYRDLPEEVPVPFEMPVLHQDEDIVVADKPHFLATMPRGRHVAQTALVRLRCELGLPEL 125 Query 130 SPAHRLDRLTAGVLLFTTRREVRGSYQTMFARGLVRKTYLARAPVAPGLALPRLVRSRIV 189 SPAHRLDRLTAGVLLFTTRRE+RG YQT+FARG VRKTYLARA V LA PR++RSRIV Sbjct 126 SPAHRLDRLTAGVLLFTTRRELRGRYQTLFARGAVRKTYLARAAVDADLAFPRVIRSRIV 185 Query 190 KRRGHLQAVCEPGVPNAETLVERIARDGLYRLTPTTGRTHQLRVHMAALGIPIMGDPLYP 249 KRRGHLQAVCEPG PNAETLVE I+ +GLYRLTP TGRTHQLRVHMA+LG+PI GDPLYP Sbjct 186 KRRGHLQAVCEPGEPNAETLVELISPEGLYRLTPRTGRTHQLRVHMASLGLPIFGDPLYP 245 Query 250 NVISVAAH---DFSTPLQLLAQRIEFDDPLTGSHREFASTRTL 289 NVI + H DFS+PL LLAQRIEF+DPL+GS REF S R + Sbjct 246 NVIPESPHDLSDFSSPLSLLAQRIEFEDPLSGSRREFVSPREI 288 >gi|240171345|ref|ZP_04750004.1| pseudouridine synthase [Mycobacterium kansasii ATCC 12478] Length=272 Score = 416 bits (1068), Expect = 3e-114, Method: Compositional matrix adjust. Identities = 214/267 (81%), Positives = 229/267 (86%), Gaps = 0/267 (0%) Query 21 VRLLGGSVLAELTARFGVAARAKVLAGEVVDDDGAVVDSGTVLPPGSVVHLYRDLPDEVP 80 +RL GG VLAEL ARFG AA KVLAGEVVD GAV+D TVLPPGS VHLYRDLPDEVP Sbjct 1 MRLNGGPVLAELDARFGTAAGRKVLAGEVVDSRGAVIDRDTVLPPGSFVHLYRDLPDEVP 60 Query 81 VPFDVPVLHQDADIVVVDKPHFLATMPRGRHVAQTALVRLRRELGLPELSPAHRLDRLTA 140 VPF++PVL+QD DIVV DKPHFLATMPRGRHVAQTALVRLR ELGLPELSPAHRLDRLTA Sbjct 61 VPFEMPVLYQDDDIVVADKPHFLATMPRGRHVAQTALVRLRCELGLPELSPAHRLDRLTA 120 Query 141 GVLLFTTRREVRGSYQTMFARGLVRKTYLARAPVAPGLALPRLVRSRIVKRRGHLQAVCE 200 GVLLFTTRRE+RG YQT+FA G V KTYLARA V P + LPR+VRSRIVKRRG LQAVCE Sbjct 121 GVLLFTTRRELRGRYQTLFACGAVHKTYLARAAVNPAVVLPRVVRSRIVKRRGQLQAVCE 180 Query 201 PGVPNAETLVERIARDGLYRLTPTTGRTHQLRVHMAALGIPIMGDPLYPNVISVAAHDFS 260 PG PNAETLVE I+ GLYRLTP TGRTHQLRVHMA+LG+PI GDPLYP V+ DFS Sbjct 181 PGEPNAETLVELISPQGLYRLTPRTGRTHQLRVHMASLGLPITGDPLYPKVLQEVDGDFS 240 Query 261 TPLQLLAQRIEFDDPLTGSHREFASTR 287 +PLQLLA+RIEFDDPLTGS REF S R Sbjct 241 SPLQLLAKRIEFDDPLTGSRREFISRR 267 >gi|254820676|ref|ZP_05225677.1| RNA pseudouridine synthase family protein [Mycobacterium intracellulare ATCC 13950] Length=271 Score = 404 bits (1037), Expect = 1e-110, Method: Compositional matrix adjust. Identities = 204/260 (79%), Positives = 229/260 (89%), Gaps = 0/260 (0%) Query 28 VLAELTARFGVAARAKVLAGEVVDDDGAVVDSGTVLPPGSVVHLYRDLPDEVPVPFDVPV 87 VLAEL+ARFG ARAKVLAGEVV DGAV+D+ TVLP G+ V+LYR+LPDEVPVPF++PV Sbjct 2 VLAELSARFGAPARAKVLAGEVVGADGAVIDAKTVLPAGASVYLYRELPDEVPVPFEIPV 61 Query 88 LHQDADIVVVDKPHFLATMPRGRHVAQTALVRLRRELGLPELSPAHRLDRLTAGVLLFTT 147 L++D DIVVVDKPHF+ATMPRGRHVAQ+ALVRLRREL LPELSPAHRLDRLTAGVL+FT Sbjct 62 LYRDDDIVVVDKPHFVATMPRGRHVAQSALVRLRRELDLPELSPAHRLDRLTAGVLMFTA 121 Query 148 RREVRGSYQTMFARGLVRKTYLARAPVAPGLALPRLVRSRIVKRRGHLQAVCEPGVPNAE 207 RREVRG++QT+F+RGLV KTYLARA V P L LPR+V+SRIVKRRG LQAVCEPG NAE Sbjct 122 RREVRGAFQTLFSRGLVDKTYLARAAVDPALRLPRVVKSRIVKRRGQLQAVCEPGAANAE 181 Query 208 TLVERIARDGLYRLTPTTGRTHQLRVHMAALGIPIMGDPLYPNVISVAAHDFSTPLQLLA 267 TLVE ++ DGLYRLTP TGRTHQLRVHMA+LGIPI GDPLYPNVI VA DFSTPL+LLA Sbjct 182 TLVELVSPDGLYRLTPRTGRTHQLRVHMASLGIPIEGDPLYPNVIDVAPDDFSTPLRLLA 241 Query 268 QRIEFDDPLTGSHREFASTR 287 +RIEF DP +G REF S R Sbjct 242 RRIEFTDPRSGVRREFVSRR 261 >gi|118464649|ref|YP_883417.1| RNA pseudouridine synthase [Mycobacterium avium 104] gi|118165936|gb|ABK66833.1| RNA pseudouridine synthase family protein [Mycobacterium avium 104] Length=287 Score = 402 bits (1032), Expect = 5e-110, Method: Compositional matrix adjust. Identities = 219/280 (79%), Positives = 237/280 (85%), Gaps = 0/280 (0%) Query 10 LSVHDVLGPVRVRLLGGSVLAELTARFGVAARAKVLAGEVVDDDGAVVDSGTVLPPGSVV 69 L V D LGP RVRL GG VLAELTARFG AARAKVLA EVV DGAVVD TVLP G+ V Sbjct 3 LPVRDGLGPARVRLRGGPVLAELTARFGAAARAKVLAAEVVTADGAVVDEATVLPAGASV 62 Query 70 HLYRDLPDEVPVPFDVPVLHQDADIVVVDKPHFLATMPRGRHVAQTALVRLRRELGLPEL 129 +LYR+LPDEV VPFD+PVLH+D DIVVVDKPHFLATMPRGRHVAQTALVRLRRELGLPEL Sbjct 63 YLYRELPDEVVVPFDLPVLHRDDDIVVVDKPHFLATMPRGRHVAQTALVRLRRELGLPEL 122 Query 130 SPAHRLDRLTAGVLLFTTRREVRGSYQTMFARGLVRKTYLARAPVAPGLALPRLVRSRIV 189 SPAHRLDRLTAGVLLFT RREVRG+YQT+F+RGLV KTYLARA V P L PR++ RIV Sbjct 123 SPAHRLDRLTAGVLLFTARREVRGAYQTLFSRGLVDKTYLARAAVDPALVFPRVLAGRIV 182 Query 190 KRRGHLQAVCEPGVPNAETLVERIARDGLYRLTPTTGRTHQLRVHMAALGIPIMGDPLYP 249 K RG +QAVCEPG PNA T VE ++ DGLYRL P TGRTHQLR+ MA+LGIPI+GDPLYP Sbjct 183 KHRGRMQAVCEPGPPNALTEVELLSPDGLYRLRPRTGRTHQLRLQMASLGIPIIGDPLYP 242 Query 250 NVISVAAHDFSTPLQLLAQRIEFDDPLTGSHREFASTRTL 289 N+I V A DFSTPLQLLAQRIEFDDP TG+ R F S RTL Sbjct 243 NMIDVPADDFSTPLQLLAQRIEFDDPRTGARRVFVSRRTL 282 >gi|41409520|ref|NP_962356.1| hypothetical protein MAP3422c [Mycobacterium avium subsp. paratuberculosis K-10] gi|41398351|gb|AAS05972.1| hypothetical protein MAP_3422c [Mycobacterium avium subsp. paratuberculosis K-10] Length=290 Score = 401 bits (1031), Expect = 6e-110, Method: Compositional matrix adjust. Identities = 218/280 (78%), Positives = 237/280 (85%), Gaps = 0/280 (0%) Query 10 LSVHDVLGPVRVRLLGGSVLAELTARFGVAARAKVLAGEVVDDDGAVVDSGTVLPPGSVV 69 L V D LGP RVRL GG VLAELTARFG AARAKVLA EVV DGAVVD TVLP G+ V Sbjct 6 LPVRDGLGPARVRLRGGPVLAELTARFGAAARAKVLAAEVVTADGAVVDEATVLPAGASV 65 Query 70 HLYRDLPDEVPVPFDVPVLHQDADIVVVDKPHFLATMPRGRHVAQTALVRLRRELGLPEL 129 +LYR+LPDEV VPFD+PVLH+D DIVVVDKPHFLATMPRGRHVAQTALVRLRRELGLPEL Sbjct 66 YLYRELPDEVVVPFDLPVLHRDDDIVVVDKPHFLATMPRGRHVAQTALVRLRRELGLPEL 125 Query 130 SPAHRLDRLTAGVLLFTTRREVRGSYQTMFARGLVRKTYLARAPVAPGLALPRLVRSRIV 189 SPAHRLDRLTAGVLLFT RREVRG+YQT+F+RGLV KTYLARA V P L PR++ RIV Sbjct 126 SPAHRLDRLTAGVLLFTARREVRGAYQTLFSRGLVDKTYLARAAVDPALVFPRVLAGRIV 185 Query 190 KRRGHLQAVCEPGVPNAETLVERIARDGLYRLTPTTGRTHQLRVHMAALGIPIMGDPLYP 249 K RG +QAVCEPG PNA T VE ++ DGLYRL P TGRTHQLR+ MA+LGIPI+GDPLYP Sbjct 186 KHRGRMQAVCEPGPPNALTEVELLSPDGLYRLRPRTGRTHQLRLQMASLGIPIIGDPLYP 245 Query 250 NVISVAAHDFSTPLQLLAQRIEFDDPLTGSHREFASTRTL 289 N+I V A DFSTPLQLLAQRIEFDDP TG+ R F + RTL Sbjct 246 NIIDVPADDFSTPLQLLAQRIEFDDPRTGARRVFVNRRTL 285 >gi|254776711|ref|ZP_05218227.1| RNA pseudouridine synthase family protein [Mycobacterium avium subsp. avium ATCC 25291] Length=287 Score = 401 bits (1030), Expect = 8e-110, Method: Compositional matrix adjust. Identities = 218/280 (78%), Positives = 237/280 (85%), Gaps = 0/280 (0%) Query 10 LSVHDVLGPVRVRLLGGSVLAELTARFGVAARAKVLAGEVVDDDGAVVDSGTVLPPGSVV 69 L V D LGP RVRL GG VLAELTARFG AARAKVLA EVV DGAVVD TVLP G+ V Sbjct 3 LPVRDGLGPARVRLRGGPVLAELTARFGAAARAKVLAAEVVTADGAVVDEATVLPAGASV 62 Query 70 HLYRDLPDEVPVPFDVPVLHQDADIVVVDKPHFLATMPRGRHVAQTALVRLRRELGLPEL 129 +LYR+LPDEV VPFD+PVLH+D DIVVVDKPHFLATMPRGRHVAQTALVRLRRELGLPEL Sbjct 63 YLYRELPDEVVVPFDLPVLHRDDDIVVVDKPHFLATMPRGRHVAQTALVRLRRELGLPEL 122 Query 130 SPAHRLDRLTAGVLLFTTRREVRGSYQTMFARGLVRKTYLARAPVAPGLALPRLVRSRIV 189 SPAHRLDRLTAGVLLFT +REVRG+YQT+F+RGLV KTYLARA V P L PR++ RIV Sbjct 123 SPAHRLDRLTAGVLLFTAQREVRGAYQTLFSRGLVDKTYLARAAVDPALVFPRVLAGRIV 182 Query 190 KRRGHLQAVCEPGVPNAETLVERIARDGLYRLTPTTGRTHQLRVHMAALGIPIMGDPLYP 249 K RG +QAVCEPG PNA T VE ++ DGLYRL P TGRTHQLR+ MA+LGIPI+GDPLYP Sbjct 183 KHRGRMQAVCEPGPPNALTEVELLSPDGLYRLRPRTGRTHQLRLQMASLGIPIIGDPLYP 242 Query 250 NVISVAAHDFSTPLQLLAQRIEFDDPLTGSHREFASTRTL 289 N+I V A DFSTPLQLLAQRIEFDDP TG+ R F S RTL Sbjct 243 NIIDVPADDFSTPLQLLAQRIEFDDPRTGARRVFVSRRTL 282 >gi|336459612|gb|EGO38547.1| 23S RNA-specific pseudouridylate synthase [Mycobacterium avium subsp. paratuberculosis S397] Length=274 Score = 389 bits (1000), Expect = 2e-106, Method: Compositional matrix adjust. Identities = 210/269 (79%), Positives = 230/269 (86%), Gaps = 0/269 (0%) Query 21 VRLLGGSVLAELTARFGVAARAKVLAGEVVDDDGAVVDSGTVLPPGSVVHLYRDLPDEVP 80 +RL GG VLAELTARFG AARAKVLA EVV DGAVVD TVLP G+ V+LYR+LPDEV Sbjct 1 MRLRGGPVLAELTARFGAAARAKVLAAEVVTADGAVVDEATVLPAGASVYLYRELPDEVV 60 Query 81 VPFDVPVLHQDADIVVVDKPHFLATMPRGRHVAQTALVRLRRELGLPELSPAHRLDRLTA 140 VPFD+PVLH+D DIVVVDKPHFLATMPRGRHVAQTALVRLRRELGLPELSPAHRLDRLTA Sbjct 61 VPFDLPVLHRDDDIVVVDKPHFLATMPRGRHVAQTALVRLRRELGLPELSPAHRLDRLTA 120 Query 141 GVLLFTTRREVRGSYQTMFARGLVRKTYLARAPVAPGLALPRLVRSRIVKRRGHLQAVCE 200 GVLLFT RREVRG+YQT+F+RGLV KTYLARA V P L PR++ RIVK RG +QAVCE Sbjct 121 GVLLFTARREVRGAYQTLFSRGLVDKTYLARAAVDPALVFPRVLAGRIVKHRGRMQAVCE 180 Query 201 PGVPNAETLVERIARDGLYRLTPTTGRTHQLRVHMAALGIPIMGDPLYPNVISVAAHDFS 260 PG PNA T VE ++ DGLYRL P TGRTHQLR+ MA+LGIPI+GDPLYPN+I V A DFS Sbjct 181 PGPPNALTEVELLSPDGLYRLRPRTGRTHQLRLQMASLGIPIIGDPLYPNIIDVPADDFS 240 Query 261 TPLQLLAQRIEFDDPLTGSHREFASTRTL 289 TPLQLLAQRIEFDDP TG+ R F + RTL Sbjct 241 TPLQLLAQRIEFDDPRTGARRVFVNRRTL 269 >gi|120402627|ref|YP_952456.1| pseudouridine synthase [Mycobacterium vanbaalenii PYR-1] gi|119955445|gb|ABM12450.1| pseudouridine synthase [Mycobacterium vanbaalenii PYR-1] Length=285 Score = 385 bits (989), Expect = 4e-105, Method: Compositional matrix adjust. Identities = 205/280 (74%), Positives = 223/280 (80%), Gaps = 1/280 (0%) Query 10 LSVHDVLGPVRVRLLGGSVLAELTARFGVAARAKVLAGEVVDDDGAVVDSGTVLPPGSVV 69 L V D LGP RVRL GG+VL EL RFG AA AKVL GEV DGAVV + TVL P SVV Sbjct 7 LPVRDGLGPARVRLRGGAVLVELADRFGEAAAAKVLNGEVFTADGAVVTASTVLQPNSVV 66 Query 70 HLYRDLPDEVPVPFDVPVLHQDADIVVVDKPHFLATMPRGRHVAQTALVRLRRELGLPEL 129 +LYRDLPDEV VPFDVPVLH+D ++VVVDKPHFLATMPRG HVAQTALVR+RREL LP+L Sbjct 67 YLYRDLPDEVAVPFDVPVLHRDDNLVVVDKPHFLATMPRGSHVAQTALVRMRRELDLPQL 126 Query 130 SPAHRLDRLTAGVLLFTTRREVRGSYQTMFARGLVRKTYLARAPVAPGLALPRLVRSRIV 189 SPAHRLDRLTAGVL+FTTRREVRG+YQTMFARG V KTYLA++ P VRSRI+ Sbjct 127 SPAHRLDRLTAGVLVFTTRREVRGAYQTMFARGGVSKTYLAQSSAGTDRDFPITVRSRII 186 Query 190 KRRGHLQAVCEPGVPNAETLVERIARDGLYRLTPTTGRTHQLRVHMAALGIPIMGDPLYP 249 KRRG LQAV EPG PNAETLVER+ D YRL P TGRTHQLRVHM +LG+PI GDPLYP Sbjct 187 KRRGTLQAVEEPGEPNAETLVERVD-DRTYRLMPRTGRTHQLRVHMNSLGLPIAGDPLYP 245 Query 250 NVISVAAHDFSTPLQLLAQRIEFDDPLTGSHREFASTRTL 289 NVI VA DFSTPL+LLAQ +EF DPL G F S RTL Sbjct 246 NVIDVAVGDFSTPLKLLAQCLEFTDPLAGVRLRFTSERTL 285 >gi|333991760|ref|YP_004524374.1| pseudouridine synthase [Mycobacterium sp. JDM601] gi|333487728|gb|AEF37120.1| pseudouridine synthase [Mycobacterium sp. JDM601] Length=384 Score = 384 bits (986), Expect = 1e-104, Method: Compositional matrix adjust. Identities = 206/280 (74%), Positives = 226/280 (81%), Gaps = 1/280 (0%) Query 10 LSVHDVLGPVRVRLLGGSVLAELTARFGVAARAKVLAGEVVDDDGAVVDSGTVLPPGSVV 69 L V D LGP R+RL GG V AEL ARFG AA AKV AGEVV DGAVVD TVLP G+ V Sbjct 9 LPVRDGLGPARLRLHGGPVAAELRARFGAAAAAKVSAGEVVTADGAVVDETTVLPAGTHV 68 Query 70 HLYRDLPDEVPVPFDVPVLHQDADIVVVDKPHFLATMPRGRHVAQTALVRLRRELGLPEL 129 LYRDLP EVPVPF++PVLH+D D+VVVDKPHFL+TMPRGRHVAQTALVRLRREL LPEL Sbjct 69 FLYRDLPVEVPVPFEIPVLHRDDDLVVVDKPHFLSTMPRGRHVAQTALVRLRRELELPEL 128 Query 130 SPAHRLDRLTAGVLLFTTRREVRGSYQTMFARGLVRKTYLARAPVAPGLALPRLVRSRIV 189 SPAHRLDRLTAGVLLFTTRRE+RG+YQT+FARG V K YLAR+ P PRLVRSRI+ Sbjct 129 SPAHRLDRLTAGVLLFTTRRELRGTYQTLFARGAVHKQYLARSSAPPAGEFPRLVRSRII 188 Query 190 KRRGHLQAVCEPGVPNAETLVERIARDGLYRLTPTTGRTHQLRVHMAALGIPIMGDPLYP 249 KRRG LQA EPG PNAETLVE + DG YRLTP TGRTHQLRVH+A+LG+PI GDPLYP Sbjct 189 KRRGCLQAREEPGEPNAETLVEALG-DGCYRLTPRTGRTHQLRVHLASLGLPIDGDPLYP 247 Query 250 NVISVAAHDFSTPLQLLAQRIEFDDPLTGSHREFASTRTL 289 ++ +A DFSTPLQLLAQR+EF DPLT R F S R Sbjct 248 EIVEIAPDDFSTPLQLLAQRLEFTDPLTQLRRCFVSRRAF 287 >gi|118473504|ref|YP_886109.1| RNA pseudouridine synthase [Mycobacterium smegmatis str. MC2 155] gi|118174791|gb|ABK75687.1| RNA pseudouridine synthase family protein [Mycobacterium smegmatis str. MC2 155] Length=291 Score = 374 bits (961), Expect = 8e-102, Method: Compositional matrix adjust. Identities = 196/277 (71%), Positives = 223/277 (81%), Gaps = 3/277 (1%) Query 13 HDVLGPVRVRLLGGSVLAELTARFGVAARAKVLAGEVVDDDGAVVDSGTVLPPGSVVHLY 72 H+ +GP R+++ GG ++ EL RFG A KV AGEV DG V+D TVLPPGS V+LY Sbjct 17 HEGIGPARLKVQGGRLVDELERRFG--AGWKVRAGEVFSRDGTVLDESTVLPPGSHVYLY 74 Query 73 RDLPDEVPVPFDVPVLHQDADIVVVDKPHFLATMPRGRHVAQTALVRLRRELGLPELSPA 132 RDLPDEV VPFD+PVL++D DIVVVDKPHFLATMPRG HV QTALVRLRREL LPEL+PA Sbjct 75 RDLPDEVDVPFDIPVLYRDDDIVVVDKPHFLATMPRGGHVTQTALVRLRRELDLPELAPA 134 Query 133 HRLDRLTAGVLLFTTRREVRGSYQTMFARGLVRKTYLARAPVAPGLALPRLVRSRIVKRR 192 HRLDRLTAGVLLFT RRE+RG+YQTMFARG V+KTYLA A P +ALP +RSRIVK R Sbjct 135 HRLDRLTAGVLLFTVRRELRGAYQTMFARGDVQKTYLAHAEGVPKIALPATLRSRIVKHR 194 Query 193 GHLQAVCEPGVPNAETLVERIARDGLYRLTPTTGRTHQLRVHMAALGIPIMGDPLYPNVI 252 G LQA EPG PNAET VE + DGLYRLTP TGRTHQLRVHMA++G+PI GDP YP VI Sbjct 195 GRLQAFEEPGEPNAETYVEAVG-DGLYRLTPRTGRTHQLRVHMASIGLPITGDPFYPTVI 253 Query 253 SVAAHDFSTPLQLLAQRIEFDDPLTGSHREFASTRTL 289 VA DFS PLQLLA+R+ FDDP++G+ REF S RTL Sbjct 254 DVAPGDFSRPLQLLAKRLMFDDPVSGARREFVSRRTL 290 >gi|145225398|ref|YP_001136076.1| pseudouridine synthase [Mycobacterium gilvum PYR-GCK] gi|145217884|gb|ABP47288.1| pseudouridine synthase [Mycobacterium gilvum PYR-GCK] Length=286 Score = 363 bits (933), Expect = 1e-98, Method: Compositional matrix adjust. Identities = 191/282 (68%), Positives = 218/282 (78%), Gaps = 3/282 (1%) Query 10 LSVHDVLGPVRVRLLGGSVLAELTARFGVAARAKVLAGEVVDDDGAVVDSGTVLPPGSVV 69 L V D LGP RVR+ GG ++ E R+G A KV+ GEV DG V D TVLPPG+ V Sbjct 7 LPVRDGLGPARVRVQGGLLVEEFQRRWGTGA--KVVDGEVFCADGTVADGSTVLPPGAYV 64 Query 70 HLYRDLPDEVPVPFDVPVLHQDADIVVVDKPHFLATMPRGRHVAQTALVRLRRELGLPEL 129 +LYRDLPDEVPVPFD+PVLH+D DIVVVDKPHFLATMPRG HVAQTALVRLRREL LPEL Sbjct 65 YLYRDLPDEVPVPFDIPVLHRDDDIVVVDKPHFLATMPRGSHVAQTALVRLRRELDLPEL 124 Query 130 SPAHRLDRLTAGVLLFTTRREVRGSYQTMFARGLVRKTYLARAPVAPGLALPRLVRSRIV 189 SPAHRLDRLTAGVLLFT RREVRG+YQT+F RG KTY+A + A P +R+R+V Sbjct 125 SPAHRLDRLTAGVLLFTVRREVRGAYQTLFVRGEAAKTYVAHSSHATDREFPMTIRNRLV 184 Query 190 KRRGHLQAVCEPGVPNAETLVERIARDGLYRLTPTTGRTHQLRVHMAALGIPIMGDPLYP 249 K RG LQAV EPG PNAET+VE + +G+YRLTP TGRTHQLRVHMA LGIPI GDPLYP Sbjct 185 KHRGSLQAVEEPGEPNAETVVEYLD-EGMYRLTPRTGRTHQLRVHMAGLGIPITGDPLYP 243 Query 250 NVISVAAHDFSTPLQLLAQRIEFDDPLTGSHREFASTRTLTG 291 +V+ V DF +PL+LLAQ +EF DP++G R F S RTL G Sbjct 244 DVVDVPPGDFGSPLRLLAQALEFTDPISGELRRFTSGRTLAG 285 >gi|315445746|ref|YP_004078625.1| 23S RNA-specific pseudouridylate synthase [Mycobacterium sp. Spyr1] gi|315264049|gb|ADU00791.1| 23S RNA-specific pseudouridylate synthase [Mycobacterium sp. Spyr1] Length=286 Score = 359 bits (922), Expect = 3e-97, Method: Compositional matrix adjust. Identities = 191/282 (68%), Positives = 216/282 (77%), Gaps = 3/282 (1%) Query 10 LSVHDVLGPVRVRLLGGSVLAELTARFGVAARAKVLAGEVVDDDGAVVDSGTVLPPGSVV 69 L V D LGP RVR+ GG ++ E R+G A KV+ GEV DG V D TVLPPG+ V Sbjct 7 LPVRDGLGPARVRVQGGLLVEEFQRRWGTGA--KVVDGEVFCADGTVADDSTVLPPGAHV 64 Query 70 HLYRDLPDEVPVPFDVPVLHQDADIVVVDKPHFLATMPRGRHVAQTALVRLRRELGLPEL 129 +LYRDLPDEVPVPFD+PVLH+D DIVVVDKPHFLATMPRG HV QTALVRLRREL LPEL Sbjct 65 YLYRDLPDEVPVPFDMPVLHRDDDIVVVDKPHFLATMPRGSHVVQTALVRLRRELDLPEL 124 Query 130 SPAHRLDRLTAGVLLFTTRREVRGSYQTMFARGLVRKTYLARAPVAPGLALPRLVRSRIV 189 SPAHRLDRLTAGVLLFT RREVRG+YQT+F RG KTY+A + A P VR+R+V Sbjct 125 SPAHRLDRLTAGVLLFTARREVRGAYQTLFVRGEAAKTYVAHSSHAIDREFPLTVRNRLV 184 Query 190 KRRGHLQAVCEPGVPNAETLVERIARDGLYRLTPTTGRTHQLRVHMAALGIPIMGDPLYP 249 K RG LQAV EPG PNAET+VE + +G+YRLTP TGRTHQLRVHMA LGIPI GDPLYP Sbjct 185 KHRGSLQAVEEPGEPNAETVVEYLG-EGMYRLTPRTGRTHQLRVHMAGLGIPITGDPLYP 243 Query 250 NVISVAAHDFSTPLQLLAQRIEFDDPLTGSHREFASTRTLTG 291 +V+ V DF PL+LLAQ +EF DP++G R F S RTL G Sbjct 244 DVVDVPPGDFGAPLRLLAQALEFTDPISGELRRFTSGRTLAG 285 >gi|126433880|ref|YP_001069571.1| pseudouridine synthase [Mycobacterium sp. JLS] gi|126233680|gb|ABN97080.1| pseudouridine synthase [Mycobacterium sp. JLS] Length=287 Score = 347 bits (890), Expect = 1e-93, Method: Compositional matrix adjust. Identities = 196/280 (70%), Positives = 221/280 (79%), Gaps = 1/280 (0%) Query 10 LSVHDVLGPVRVRLLGGSVLAELTARFGVAARAKVLAGEVVDDDGAVVDSGTVLPPGSVV 69 L V D LGP RVRL GG+VL EL RFG A AKV G V+ DG+ V TVLPPG+ V Sbjct 9 LPVRDGLGPARVRLRGGAVLVELADRFGEAVAAKVFDGGVLTADGSAVTPATVLPPGTHV 68 Query 70 HLYRDLPDEVPVPFDVPVLHQDADIVVVDKPHFLATMPRGRHVAQTALVRLRRELGLPEL 129 +LYRDLP EVPVPF +PVLH+D +IVVVDKPHFLATMPRGRHVA+TA+VRLRR L LPEL Sbjct 69 YLYRDLPVEVPVPFAMPVLHRDDNIVVVDKPHFLATMPRGRHVAETAVVRLRRALDLPEL 128 Query 130 SPAHRLDRLTAGVLLFTTRREVRGSYQTMFARGLVRKTYLARAPVAPGLALPRLVRSRIV 189 SPAHRLDRLTAGVLLFTTRRE+RG+YQTMF+ G V K YLAR+ + LP +VRSRI+ Sbjct 129 SPAHRLDRLTAGVLLFTTRREIRGAYQTMFSDGAVAKVYLARSAGHATVDLPTVVRSRII 188 Query 190 KRRGHLQAVCEPGVPNAETLVERIARDGLYRLTPTTGRTHQLRVHMAALGIPIMGDPLYP 249 K RG LQA PG PNAETLVE + D +YRLTP TGRTHQLRVHMA+LG+P++GDPLYP Sbjct 189 KERGRLQAFEAPGEPNAETLVEHLG-DDVYRLTPRTGRTHQLRVHMASLGLPLLGDPLYP 247 Query 250 NVISVAAHDFSTPLQLLAQRIEFDDPLTGSHREFASTRTL 289 +VI VA DFSTPLQLLA IEFDDPLTG F + RTL Sbjct 248 DVIDVAPDDFSTPLQLLANSIEFDDPLTGRPHRFVTGRTL 287 >gi|108798222|ref|YP_638419.1| pseudouridine synthase [Mycobacterium sp. MCS] gi|119867318|ref|YP_937270.1| pseudouridine synthase [Mycobacterium sp. KMS] gi|108768641|gb|ABG07363.1| pseudouridine synthase [Mycobacterium sp. MCS] gi|119693407|gb|ABL90480.1| pseudouridine synthase [Mycobacterium sp. KMS] Length=287 Score = 344 bits (883), Expect = 1e-92, Method: Compositional matrix adjust. Identities = 195/280 (70%), Positives = 221/280 (79%), Gaps = 1/280 (0%) Query 10 LSVHDVLGPVRVRLLGGSVLAELTARFGVAARAKVLAGEVVDDDGAVVDSGTVLPPGSVV 69 L V D LGP RVRL GG+VL EL RFG A AKV G VV DG VV GTVLPPG+ V Sbjct 9 LPVRDGLGPARVRLRGGAVLVELADRFGEAVAAKVFDGGVVCADGTVVRPGTVLPPGTHV 68 Query 70 HLYRDLPDEVPVPFDVPVLHQDADIVVVDKPHFLATMPRGRHVAQTALVRLRRELGLPEL 129 +LYRDLP EVPVPF +PVL++D +IVVVDKPHFLATMPRGRHVA+TA+VRLRR L LPEL Sbjct 69 YLYRDLPVEVPVPFAMPVLYRDDNIVVVDKPHFLATMPRGRHVAETAVVRLRRALDLPEL 128 Query 130 SPAHRLDRLTAGVLLFTTRREVRGSYQTMFARGLVRKTYLARAPVAPGLALPRLVRSRIV 189 SPAHRLDRLTAGVLLFTTRRE+RG+YQTMF+ G V K YLAR+ + LP +VRSRI+ Sbjct 129 SPAHRLDRLTAGVLLFTTRREIRGAYQTMFSDGAVAKVYLARSAGHAAVDLPTVVRSRII 188 Query 190 KRRGHLQAVCEPGVPNAETLVERIARDGLYRLTPTTGRTHQLRVHMAALGIPIMGDPLYP 249 K RG LQA PG PNAETLVE + D +YRLTP TGRTHQLRVHM++LG+P++GDPLYP Sbjct 189 KERGRLQAFEAPGEPNAETLVEHLG-DDVYRLTPRTGRTHQLRVHMSSLGLPLLGDPLYP 247 Query 250 NVISVAAHDFSTPLQLLAQRIEFDDPLTGSHREFASTRTL 289 +VI VA DF+ PLQLLA IEFDDPLTG F + RTL Sbjct 248 DVIDVAPDDFADPLQLLAHSIEFDDPLTGRPHRFVTGRTL 287 >gi|169630733|ref|YP_001704382.1| pseudouridine synthase [Mycobacterium abscessus ATCC 19977] gi|169242700|emb|CAM63728.1| Pseudouridine synthase [Mycobacterium abscessus] Length=277 Score = 308 bits (790), Expect = 6e-82, Method: Compositional matrix adjust. Identities = 167/275 (61%), Positives = 203/275 (74%), Gaps = 4/275 (1%) Query 19 VRVRLL-GGSVLAELTARFGVAARAKVLAGEVVDDDGAVVDSGTVLPPGSVVHLYRDLPD 77 +R+RL GG V+ EL ARFG AA +V GEVVD G V +GT LP G+VV+ YR+ + Sbjct 1 MRIRLHDGGRVVDELVARFGPAAVDQVDRGEVVDSAGMRVTAGTRLPAGAVVYTYREPAE 60 Query 78 EVPVPFDVPVLHQDADIVVVDKPHFLATMPRGRHVAQTALVRLRRELGLPELSPAHRLDR 137 E+ VPF + VLH D +++VVDKPHFLATMPRGRHV +TALVRLR+ L LPEL+PAHRLDR Sbjct 61 EISVPFAIDVLHWDENVLVVDKPHFLATMPRGRHVTETALVRLRKMLDLPELAPAHRLDR 120 Query 138 LTAGVLLFTTRREVRGSYQTMFARGLVRKTYLARAPVAPGLALPRLVRSRIVKRRGHLQA 197 LTAGVLLFT RR+ R +Y ++FA+ V K Y A APV PGL+LP VRSRIVKRR LQA Sbjct 121 LTAGVLLFTVRRDARAAYHSLFAQRQVVKIYEALAPVKPGLSLPLTVRSRIVKRRSILQA 180 Query 198 VCEPGVPNAETLVERIARD---GLYRLTPTTGRTHQLRVHMAALGIPIMGDPLYPNVISV 254 V EPG NAET VE + R G YRLTP+TG+THQLRVHM ++G+PI+ DPLYP+V+ V Sbjct 181 VEEPGPANAETRVELVDRHHAVGRYRLTPSTGQTHQLRVHMNSMGVPILNDPLYPDVVEV 240 Query 255 AAHDFSTPLQLLAQRIEFDDPLTGSHREFASTRTL 289 DF+ PLQLLA+ + F DPL G + S R L Sbjct 241 PPDDFTRPLQLLARTLAFRDPLNGKDVRYESGRAL 275 >gi|302526188|ref|ZP_07278530.1| ribosomal pseudouridine synthase [Streptomyces sp. AA4] gi|302435083|gb|EFL06899.1| ribosomal pseudouridine synthase [Streptomyces sp. AA4] Length=309 Score = 286 bits (732), Expect = 2e-75, Method: Compositional matrix adjust. Identities = 166/297 (56%), Positives = 202/297 (69%), Gaps = 15/297 (5%) Query 16 LGPVRVRLL----GGSVLAELTARFGVAARAKVLA----GEVVDDDGAV-VDSGTVLPPG 66 L P R+RL ++L L R A A++ + +DG + +D+ V PG Sbjct 15 LDPARLRLPEEGPWTTLLEHLVERLPRVAPARIEEMLHEQRIHGEDGPLGIDAAYV--PG 72 Query 67 SVVHLYRDLPDEVPVPFDVPVLHQDADIVVVDKPHFLATMPRGRHVAQTALVRLRRELGL 126 S + +RDLPDEVPVPFDV VLH+D ++VVDKPHFLAT+PRGRHV +TALVRLRR L L Sbjct 73 SFIWFHRDLPDEVPVPFDVTVLHRDDHLLVVDKPHFLATIPRGRHVLETALVRLRRSLDL 132 Query 127 PELSPAHRLDRLTAGVLLFTTRREVRGSYQTMFARGLVRKTYLARAPVAPGLALPRLVRS 186 P LSPAHRLDR+TAG+++F RG+YQTMF LV K Y A AP P L LPR+VRS Sbjct 133 PALSPAHRLDRVTAGLVMFVITPSARGAYQTMFRDRLVHKEYEAIAPYDPTLELPRVVRS 192 Query 187 RIVKRRGHLQAVCEPGVPNAETLVERIA-RDGL--YRLTPTTGRTHQLRVHMAALGIPIM 243 RIVK RG L A PG PNAE+ VE + RDGL YRLTP TGRTHQLRVHM +LGIPI+ Sbjct 193 RIVKERGVLAAQEVPGPPNAESTVELLEHRDGLGRYRLTPATGRTHQLRVHMCSLGIPIL 252 Query 244 GDPLYPNVISVAAHDFSTPLQLLAQRIEFDDPLTGSHREFASTRTLTGA-TLPTWSA 299 GD YP + +DF+ PLQLLA+ +EFDDPLTG HR F S RTL+ +L W++ Sbjct 253 GDDFYPELHEKPLNDFTKPLQLLAKVLEFDDPLTGEHRRFTSRRTLSAWDSLDAWAS 309 >gi|134099890|ref|YP_001105551.1| ribosomal pseudouridine synthase [Saccharopolyspora erythraea NRRL 2338] gi|291006074|ref|ZP_06564047.1| ribosomal pseudouridine synthase [Saccharopolyspora erythraea NRRL 2338] gi|133912513|emb|CAM02626.1| ribosomal pseudouridine synthase [Saccharopolyspora erythraea NRRL 2338] Length=312 Score = 283 bits (725), Expect = 2e-74, Method: Compositional matrix adjust. Identities = 157/258 (61%), Positives = 181/258 (71%), Gaps = 9/258 (3%) Query 49 VVDDDGAVVDSGTVLPPGSVVHLYRDLPDEVPVPFDVPVLHQDADIVVVDKPHFLATMPR 108 VVD G V +P GS V +RDLPDEVPVPF++ V+H+D D++VVDKPHFLAT PR Sbjct 55 VVDLHGPVAADAPFVP-GSFVWFHRDLPDEVPVPFEIGVVHRDDDLLVVDKPHFLATTPR 113 Query 109 GRHVAQTALVRLRRELGLPELSPAHRLDRLTAGVLLFTTRREVRGSYQTMFARGLVRKTY 168 GRHVAQTALVRLRREL +P+LSPAHRLDR TAG+++F R E+R SYQ MF LV K Y Sbjct 114 GRHVAQTALVRLRRELSIPDLSPAHRLDRTTAGLVMFVIRPELRKSYQEMFQNRLVHKEY 173 Query 169 LARAPVAPGLALPRLVRSRIVKRRGHLQAVCEPGVPNAETLVERIA-RDGL--YRLTPTT 225 A AP PGL LPR VRSRIVK RG L A PG PNAETLVE + RDGL YRL P T Sbjct 174 EAVAPFDPGLELPRTVRSRIVKERGVLAAQEVPGPPNAETLVELLEHRDGLGRYRLLPKT 233 Query 226 GRTHQLRVHMAALGIPIMGDPLYPNVISVAAHDFSTPLQLLAQRIEFDDPLTGSHREFAS 285 GRTHQLRVH+ ++GIPI+GD YP V A DF PLQLLA+ +EF DP++G HR F S Sbjct 234 GRTHQLRVHLNSIGIPILGDDTYPVVNDPAPDDFGRPLQLLAKALEFTDPVSGLHRRFES 293 Query 286 TRTLTGATLPTWSAAADC 303 G L W + D Sbjct 294 -----GLALGAWKSYEDW 306 >gi|325674660|ref|ZP_08154347.1| RNA pseudouridine synthase [Rhodococcus equi ATCC 33707] gi|325554246|gb|EGD23921.1| RNA pseudouridine synthase [Rhodococcus equi ATCC 33707] Length=297 Score = 280 bits (717), Expect = 2e-73, Method: Compositional matrix adjust. Identities = 162/291 (56%), Positives = 199/291 (69%), Gaps = 10/291 (3%) Query 10 LSVHDVLGPVRVRLLGG----SVLAELTARF-GVAAR--AKVLAGEVVDDDGAVVDSGTV 62 L V D L P R+RL + L L +RF G A R KV AGEVVD+ G +D+ T Sbjct 6 LPVRDGLNPTRLRLPDDGAWPTALGYLLSRFPGDAKRLQEKVDAGEVVDEHGTPIDAVTA 65 Query 63 LPPGSVVHLYRDLPDEVPVPFDVPVLHQDADIVVVDKPHFLATMPRGRHVAQTALVRLRR 122 P + ++LYRD P E VPF+V VLH+D D++VVDKPHFLA+ PRG +V ++ALVRLRR Sbjct 66 YRPRAFLYLYRDPPAEKRVPFEVDVLHRDQDLLVVDKPHFLASTPRGAYVVESALVRLRR 125 Query 123 ELGLPELSPAHRLDRLTAGVLLFTTRREVRGSYQTMFARGLVRKTYLARAPVAPGLALPR 182 EL LPEL+PAHRLDR+TAGVLLFT RRE R +YQ++F K Y A A P L LP Sbjct 126 ELDLPELTPAHRLDRITAGVLLFTVRREARRAYQSLFDERRATKVYEALARHDPSLHLPV 185 Query 183 LVRSRIVKRRGHLQAVCEPGVPNAETLVERI-ARDGL--YRLTPTTGRTHQLRVHMAALG 239 VRSRI+K RG LQA G PNAE+ +E + RDG+ YRL P TG+THQLR+HM +LG Sbjct 186 TVRSRIIKERGVLQAREVDGEPNAESRIELLDVRDGVGHYRLLPRTGKTHQLRLHMCSLG 245 Query 240 IPIMGDPLYPNVISVAAHDFSTPLQLLAQRIEFDDPLTGSHREFASTRTLT 290 +PI+GD YP VA+ D+S PL+LLA+ +EFDDP TG R F S RTLT Sbjct 246 VPIIGDNFYPRFYDVASDDYSDPLRLLARSLEFDDPYTGVRRRFESRRTLT 296 >gi|312138349|ref|YP_004005685.1| tRNA-pseudouridine synthase i [Rhodococcus equi 103S] gi|311887688|emb|CBH47000.1| putative tRNA-pseudouridine synthase I [Rhodococcus equi 103S] Length=297 Score = 280 bits (716), Expect = 2e-73, Method: Compositional matrix adjust. Identities = 162/291 (56%), Positives = 199/291 (69%), Gaps = 10/291 (3%) Query 10 LSVHDVLGPVRVRLLGG----SVLAELTARF-GVAAR--AKVLAGEVVDDDGAVVDSGTV 62 L V D L P R+RL + L L +RF G A R KV AGEVVD+ G +D+ T Sbjct 6 LPVRDGLNPTRLRLPDDGAWPTALGYLLSRFPGDAKRLQEKVDAGEVVDEHGTPIDAVTA 65 Query 63 LPPGSVVHLYRDLPDEVPVPFDVPVLHQDADIVVVDKPHFLATMPRGRHVAQTALVRLRR 122 P + ++LYRD P E VPF+V VLH+D D++VVDKPHFLA+ PRG +V ++ALVRLRR Sbjct 66 YRPRAFLYLYRDPPAEKRVPFEVDVLHRDQDLLVVDKPHFLASTPRGAYVVESALVRLRR 125 Query 123 ELGLPELSPAHRLDRLTAGVLLFTTRREVRGSYQTMFARGLVRKTYLARAPVAPGLALPR 182 EL LPEL+PAHRLDR+TAGVLLFT RRE R +YQ++F K Y A A P L LP Sbjct 126 ELDLPELTPAHRLDRITAGVLLFTVRREARRAYQSLFDERRATKVYEALARHDPSLHLPV 185 Query 183 LVRSRIVKRRGHLQAVCEPGVPNAETLVERI-ARDGL--YRLTPTTGRTHQLRVHMAALG 239 VRSRI+K RG LQA G PNAE+ +E + RDG+ YRL P TG+THQLR+HM +LG Sbjct 186 TVRSRIIKERGVLQAREVDGEPNAESRIELLDVRDGVGHYRLLPRTGKTHQLRLHMCSLG 245 Query 240 IPIMGDPLYPNVISVAAHDFSTPLQLLAQRIEFDDPLTGSHREFASTRTLT 290 +PI+GD YP VA+ D+S PL+LLA+ +EFDDP TG R F S RTLT Sbjct 246 VPIIGDNFYPRFYDVASDDYSDPLRLLARSLEFDDPYTGIRRRFESRRTLT 296 >gi|111021862|ref|YP_704834.1| pseudouridylate synthase [Rhodococcus jostii RHA1] gi|110821392|gb|ABG96676.1| pseudouridylate synthase [Rhodococcus jostii RHA1] Length=338 Score = 275 bits (702), Expect = 8e-72, Method: Compositional matrix adjust. Identities = 158/293 (54%), Positives = 196/293 (67%), Gaps = 10/293 (3%) Query 7 DRLLSVHDVLGPVRVRL--LGG--SVLAELTARF---GVAARAKVLAGEVVDDDGAVVDS 59 D L V D L P R+R+ +G +VL L ARF R KV A EVVD+ G + Sbjct 42 DAPLPVRDGLNPTRLRMPDVGAWPTVLEYLVARFPHDETRLREKVAAAEVVDERGQPITE 101 Query 60 GTVLPPGSVVHLYRDLPDEVPVPFDVPVLHQDADIVVVDKPHFLATMPRGRHVAQTALVR 119 T P V+LYRD P E VPFD+ +LH+D D++VVDKPHFLA+ PRG +VA++ALVR Sbjct 102 ATPFAPRKFVYLYRDPPVEKRVPFDIEILHRDEDLLVVDKPHFLASTPRGAYVAESALVR 161 Query 120 LRRELGLPELSPAHRLDRLTAGVLLFTTRREVRGSYQTMFARGLVRKTYLARAPVAPGLA 179 LRR+ LPEL+PAHRLDRLTAGVL+FT RREVR YQ++F + V K Y A A P L Sbjct 162 LRRDFDLPELTPAHRLDRLTAGVLIFTVRREVRRDYQSLFDQRRVVKEYEAVARYDPDLR 221 Query 180 LPRLVRSRIVKRRGHLQAVCEPGVPNAETLVERIARDG---LYRLTPTTGRTHQLRVHMA 236 LP VRSRIVK RG L+A G N+E+ +E + G YRL P TG+THQLR+HM+ Sbjct 222 LPATVRSRIVKERGVLKAYEMDGPANSESRIELLEIHGDAARYRLLPHTGKTHQLRLHMS 281 Query 237 ALGIPIMGDPLYPNVISVAAHDFSTPLQLLAQRIEFDDPLTGSHREFASTRTL 289 +LGIPI GD YP+ VAA D+STPL+LLA+ +EF DP +G R FAS R+L Sbjct 282 SLGIPIHGDNFYPDFYDVAADDYSTPLRLLARSVEFVDPYSGVTRRFASVRSL 334 >gi|54022716|ref|YP_116958.1| putative RNA pseudouridylate synthase [Nocardia farcinica IFM 10152] gi|54014224|dbj|BAD55594.1| putative RNA pseudouridylate synthase [Nocardia farcinica IFM 10152] Length=309 Score = 274 bits (701), Expect = 1e-71, Method: Compositional matrix adjust. Identities = 162/297 (55%), Positives = 199/297 (68%), Gaps = 15/297 (5%) Query 16 LGPVRVRLLGGSVLAELTARFGVAARAKVLAGEVVDD---DGAVVD-SGTVLP-----PG 66 L P R+RL A T R + R +A E +D+ GA+VD G + P PG Sbjct 15 LDPARLRLPEAGEWA--TIRDHLVHRLPRVAPERIDELLRAGAIVDLDGPIAPDAPYVPG 72 Query 67 SVVHLYRDLPDEVPVPFDVPVLHQDADIVVVDKPHFLATMPRGRHVAQTALVRLRRELGL 126 V +RDLPDEV VPFD+ V+H+D ++VVDKPHFLAT+PRG+H+ QTALVRLR +LGL Sbjct 73 GAVWFHRDLPDEVEVPFDLTVVHRDETVLVVDKPHFLATIPRGQHIRQTALVRLREQLGL 132 Query 127 PELSPAHRLDRLTAGVLLFTTRREVRGSYQTMFARGLVRKTYLARAPVAPGLALPRLVRS 186 P+L PAHRLDR+TAG++LF RG+YQTMF R VRK Y A AP P LALPR+VRS Sbjct 133 PDLVPAHRLDRVTAGLILFVVDPARRGAYQTMFHRRTVRKQYEAIAPFDPELALPRVVRS 192 Query 187 RIVKRRGHLQAVCEPGVPNAETLVERIA-RDGL--YRLTPTTGRTHQLRVHMAALGIPIM 243 RIVK + L A G PNAETLVE + RDGL YRLTP TGRTHQLR+HM +LG+PI+ Sbjct 193 RIVKEKHVLAAREVEGEPNAETLVELLEHRDGLGRYRLTPHTGRTHQLRLHMNSLGVPIL 252 Query 244 GDPLYPNVISVAAHDFSTPLQLLAQRIEFDDPLTGSHREFASTRTLTGAT-LPTWSA 299 GD YP + H+F+ PLQLLA +EF DP+TG R F +TR+L T P W+ Sbjct 253 GDDFYPVLTDKPVHEFTRPLQLLAAVLEFTDPVTGEPRRFETTRSLQAWTDYPGWAG 309 >gi|226308249|ref|YP_002768209.1| pseudouridine synthase [Rhodococcus erythropolis PR4] gi|226187366|dbj|BAH35470.1| putative pseudouridine synthase [Rhodococcus erythropolis PR4] Length=323 Score = 274 bits (700), Expect = 2e-71, Method: Compositional matrix adjust. Identities = 151/291 (52%), Positives = 194/291 (67%), Gaps = 10/291 (3%) Query 10 LSVHDVLGPVRVRL----LGGSVLAELTARF---GVAARAKVLAGEVVDDDGAVVDSGTV 62 L V D L P R+R + + L L RF V R KV AGEVVD+ G + + Sbjct 22 LPVRDGLNPSRIRQPDDGMWATTLDYLLERFPQDAVRLREKVAAGEVVDEKGVAITETSG 81 Query 63 LPPGSVVHLYRDLPDEVPVPFDVPVLHQDADIVVVDKPHFLATMPRGRHVAQTALVRLRR 122 P V+LYRD P E VPF++ +L++D +I+VVDKPHFLA+ PRGR++A++ALVRLRR Sbjct 82 FAPRRFVYLYRDAPVEARVPFEIDILYRDENILVVDKPHFLASTPRGRYIAESALVRLRR 141 Query 123 ELGLPELSPAHRLDRLTAGVLLFTTRREVRGSYQTMFARGLVRKTYLARAPVAPGLALPR 182 +L LPELSPAHRLDR+TAG+LLFT + R YQTMFA V K Y A A ++ P Sbjct 142 DLDLPELSPAHRLDRVTAGLLLFTVHQAARRGYQTMFAERRVTKEYEAIARYDAQVSTPV 201 Query 183 LVRSRIVKRRGHLQAVCEPGVPNAETLVERI-ARDGL--YRLTPTTGRTHQLRVHMAALG 239 +VRSRIVK RG L+A G PN+E+ +E I RDG YRL P TG+THQLR+HM +LG Sbjct 202 VVRSRIVKERGVLKAAEIEGEPNSESRIELIETRDGFARYRLIPHTGKTHQLRLHMTSLG 261 Query 240 IPIMGDPLYPNVISVAAHDFSTPLQLLAQRIEFDDPLTGSHREFASTRTLT 290 +PI GD YP+ VAA D+S PL+LL++ +EF+DP TG + F S RTL+ Sbjct 262 LPIHGDNFYPDFYDVAAEDYSNPLRLLSKVLEFEDPTTGRLQRFESRRTLS 312 >gi|302550275|ref|ZP_07302617.1| ribosomal pseudouridine synthase [Streptomyces viridochromogenes DSM 40736] gi|302467893|gb|EFL30986.1| ribosomal pseudouridine synthase [Streptomyces viridochromogenes DSM 40736] Length=317 Score = 273 bits (698), Expect = 2e-71, Method: Compositional matrix adjust. Identities = 167/305 (55%), Positives = 192/305 (63%), Gaps = 17/305 (5%) Query 18 PVRVRLLGGSVLA--------ELTARFGVAARAKVLAGEVVDDDGAVVDSGTVLPPGSVV 69 PVRVRL A LT + AG VV DG V + PG+ V Sbjct 9 PVRVRLPAEGAWATVREHLVERLTGAGDGVVNSMFEAGLVVGADGRAVAADAPYAPGAFV 68 Query 70 HLYRDLPDEVPVPFDVPVLHQDADIVVVDKPHFLATMPRGRHVAQTALVRLRRELGLPEL 129 +RDLPDEVPVPF + V+H+D IVV DKPHFLAT PRG HVA+TAL RLRRELG+P L Sbjct 69 WFHRDLPDEVPVPFPLEVVHRDEHIVVADKPHFLATTPRGSHVAETALARLRRELGIPAL 128 Query 130 SPAHRLDRLTAGVLLFTTRREVRGSYQTMFARGLVRKTYLARAPVAPGLALPRLVRSRIV 189 + AHRLDRLTAG++LFT R E RG+YQT+F VRK Y A AP PGLALPR VRSRIV Sbjct 129 TAAHRLDRLTAGLVLFTVRLEDRGAYQTLFRDRRVRKEYEAVAPHDPGLALPRTVRSRIV 188 Query 190 KRRGHLQAVCEPGVPNAETLVE----RIARDG---LYRLTPTTGRTHQLRVHMAALGIPI 242 K RG L A G PNA + +E R A G YRL P TG+THQLRVHM ALG+PI Sbjct 189 KERGVLTAREVAGEPNAVSRIELVEHRAAGSGGLARYRLVPGTGQTHQLRVHMTALGVPI 248 Query 243 MGDPLYPNVIS-VAAHDFSTPLQLLAQRIEFDDPLTGSHREFASTRTLTG-ATLPTWSAA 300 +GDPLYP V + V A DF PLQLLA+ +EF DP+TG F S R L A+ W+A Sbjct 249 LGDPLYPEVTAPVPAGDFRRPLQLLARTLEFTDPVTGEEHRFRSGRELAAWASYDRWAAG 308 Query 301 ADCRP 305 D P Sbjct 309 TDDGP 313 >gi|229488989|ref|ZP_04382855.1| pseudouridylate synthase [Rhodococcus erythropolis SK121] gi|229324493|gb|EEN90248.1| pseudouridylate synthase [Rhodococcus erythropolis SK121] Length=307 Score = 273 bits (698), Expect = 2e-71, Method: Compositional matrix adjust. Identities = 152/291 (53%), Positives = 195/291 (68%), Gaps = 10/291 (3%) Query 10 LSVHDVLGPVRVRL----LGGSVLAELTARF---GVAARAKVLAGEVVDDDGAVVDSGTV 62 L V D L P R+R + + L L RF V R KV AGEVVD+ G + + Sbjct 6 LPVRDGLNPSRIRQPDDGMWTTTLDYLLERFPQDAVRLREKVAAGEVVDEKGVGITETSA 65 Query 63 LPPGSVVHLYRDLPDEVPVPFDVPVLHQDADIVVVDKPHFLATMPRGRHVAQTALVRLRR 122 P V+LYRD P E VPF++ +L++D +I+VVDKPHFLA+ PRGR++A++ALVRLRR Sbjct 66 FAPRRFVYLYRDAPVEARVPFEIDILYRDENILVVDKPHFLASTPRGRYIAESALVRLRR 125 Query 123 ELGLPELSPAHRLDRLTAGVLLFTTRREVRGSYQTMFARGLVRKTYLARAPVAPGLALPR 182 +L LPELSPAHRLDR+TAG+LLFT + R YQTMFA V K Y A A ++ P Sbjct 126 DLELPELSPAHRLDRVTAGLLLFTVHQAARRDYQTMFAERRVAKEYEAIARHDAQVSTPV 185 Query 183 LVRSRIVKRRGHLQAVCEPGVPNAETLVERI-ARDGL--YRLTPTTGRTHQLRVHMAALG 239 +VRSRIVK RG L+A G PN+E+ +E I RDG YRLTP TG+THQLR+HM +LG Sbjct 186 VVRSRIVKERGVLKAAEIEGEPNSESRIELIETRDGFARYRLTPHTGKTHQLRLHMTSLG 245 Query 240 IPIMGDPLYPNVISVAAHDFSTPLQLLAQRIEFDDPLTGSHREFASTRTLT 290 +PI GD YP+ VAA D+S PL+LL++ +EF+DP TG + F S RTL+ Sbjct 246 LPIHGDNFYPDFYDVAAEDYSNPLRLLSKVLEFEDPKTGRLQRFESRRTLS 296 >gi|111017875|ref|YP_700847.1| pseudouridylate synthase [Rhodococcus jostii RHA1] gi|110817405|gb|ABG92689.1| possible pseudouridylate synthase [Rhodococcus jostii RHA1] Length=297 Score = 272 bits (696), Expect = 4e-71, Method: Compositional matrix adjust. Identities = 154/290 (54%), Positives = 192/290 (67%), Gaps = 10/290 (3%) Query 10 LSVHDVLGPVRVRL---LGGSVLAELTARFGVAARAKVLA----GEVVDDDGAVVDSGTV 62 L V + LGP R+R+ +G +AE RA L+ GEVVD+ G VVD GT Sbjct 6 LPVRNGLGPDRIRMPAGVGTKTVAEFLVETYPDERAHWLSLIDGGEVVDEHGRVVDRGTR 65 Query 63 LPPGSVVHLYRDLPDEVPVPFDVPVLHQDADIVVVDKPHFLATMPRGRHVAQTALVRLRR 122 P V+ YRD E+PVPF++ +LH+D +VV+DKPHFLAT+PRG H+ +TA+VRLRR Sbjct 66 YAPTRFVYFYRDPAPEIPVPFEIDILHRDDHLVVIDKPHFLATIPRGAHITETAVVRLRR 125 Query 123 ELGLPELSPAHRLDRLTAGVLLFTTRREVRGSYQTMFARGLVRKTYLARAPVAPGLALPR 182 L LP+L+PAHRLDR+TAGVL+F RRE R YQ +F V K Y A A P LA PR Sbjct 126 ALDLPDLTPAHRLDRMTAGVLVFLIRREDRRPYQELFVSQQVTKEYEAVAGHDPALAFPR 185 Query 183 LVRSRIVKRRGHLQAVCEPGVPNAETLVERI-ARDG--LYRLTPTTGRTHQLRVHMAALG 239 +RSRIVK G + A EPG PN+ET+V+ + RDG YRL P TGRTHQLR+HM++LG Sbjct 186 TIRSRIVKEHGIMTATEEPGEPNSETVVDLLDTRDGRARYRLLPKTGRTHQLRLHMSSLG 245 Query 240 IPIMGDPLYPNVISVAAHDFSTPLQLLAQRIEFDDPLTGSHREFASTRTL 289 +PI GD YP+ DFSTPL+LLA+ IEF DP +G R F S RTL Sbjct 246 LPIEGDNYYPDFRRSEPGDFSTPLRLLARAIEFTDPRSGEVRRFESRRTL 295 >gi|226364380|ref|YP_002782162.1| pseudouridine synthase [Rhodococcus opacus B4] gi|226242869|dbj|BAH53217.1| putative pseudouridine synthase [Rhodococcus opacus B4] Length=302 Score = 272 bits (695), Expect = 5e-71, Method: Compositional matrix adjust. Identities = 156/293 (54%), Positives = 194/293 (67%), Gaps = 10/293 (3%) Query 7 DRLLSVHDVLGPVRVRLLGG----SVLAELTARF---GVAARAKVLAGEVVDDDGAVVDS 59 D L V D L P R+R+ +VL L ARF R KV EVVD+ G + Sbjct 6 DAPLPVRDGLNPTRLRMPDTGPWPTVLGYLVARFPHDETRLREKVATAEVVDERGQPITE 65 Query 60 GTVLPPGSVVHLYRDLPDEVPVPFDVPVLHQDADIVVVDKPHFLATMPRGRHVAQTALVR 119 T P V+LYRD P E VPF++ +LH+D +++VVDKPHFLA+ PRG +VA++ALVR Sbjct 66 STPFAPRRFVYLYRDPPVEKRVPFEIEILHRDENLLVVDKPHFLASTPRGAYVAESALVR 125 Query 120 LRRELGLPELSPAHRLDRLTAGVLLFTTRREVRGSYQTMFARGLVRKTYLARAPVAPGLA 179 LRR+L LPEL+PAHRLDRLTAGVL+FT RREVR YQ++F + V K Y A A P L Sbjct 126 LRRDLDLPELTPAHRLDRLTAGVLIFTVRREVRRDYQSLFDQRRVTKEYEAVARYDPDLL 185 Query 180 LPRLVRSRIVKRRGHLQAVCEPGVPNAETLVERIARDGL---YRLTPTTGRTHQLRVHMA 236 LP VRSRIVK RG L+A G N+E+ +E + G YRL P TG+THQLRVHM+ Sbjct 186 LPATVRSRIVKERGVLKAYEVDGPANSESRIELLEVHGAAARYRLLPHTGKTHQLRVHMS 245 Query 237 ALGIPIMGDPLYPNVISVAAHDFSTPLQLLAQRIEFDDPLTGSHREFASTRTL 289 +LGIPI GD YP+ VAA D+STPL+LLA+ +EF DP +G R FAS R+L Sbjct 246 SLGIPIHGDNFYPDFYDVAADDYSTPLRLLARSVEFADPCSGVTRRFASVRSL 298 >gi|291440659|ref|ZP_06580049.1| ribosomal pseudouridine synthase [Streptomyces ghanaensis ATCC 14672] gi|291343554|gb|EFE70510.1| ribosomal pseudouridine synthase [Streptomyces ghanaensis ATCC 14672] Length=319 Score = 271 bits (694), Expect = 7e-71, Method: Compositional matrix adjust. Identities = 166/301 (56%), Positives = 192/301 (64%), Gaps = 15/301 (4%) Query 14 DVLGPVRVRLLGGSVLA--------ELTARFGVAARAKVLAGEVVDDDGAVVDSGTVLPP 65 D + PVRVRL G A L+A GV AG +V DG V + P Sbjct 19 DGVDPVRVRLPAGGSWATVRDHLVQRLSAGPGVVD-GMFAAGLIVGADGRAVPADAPYEP 77 Query 66 GSVVHLYRDLPDEVPVPFDVPVLHQDADIVVVDKPHFLATMPRGRHVAQTALVRLRRELG 125 G + +R+LP EVPVPF + V+H+D IVVVDKPHFLAT PRG HVAQTAL RLRRELG Sbjct 78 GLFLWFHRELPAEVPVPFPLEVVHRDEHIVVVDKPHFLATTPRGSHVAQTALARLRRELG 137 Query 126 LPELSPAHRLDRLTAGVLLFTTRREVRGSYQTMFARGLVRKTYLARAPVAPGLALPRLVR 185 +PEL AHRLDRLTAG++LFT R RG+YQT+F V K Y A AP PGL LPR VR Sbjct 138 IPELGAAHRLDRLTAGLVLFTVRPGERGAYQTLFRDRRVHKEYEAVAPYDPGLDLPRTVR 197 Query 186 SRIVKRRGHLQAVCEPGVPNAETLVE----RIARDGLYRLTPTTGRTHQLRVHMAALGIP 241 SRIVK RG L A G PNA TLVE R G YRL P TG+THQLRVHM+ALG+P Sbjct 198 SRIVKERGELAAREVEGEPNALTLVELTEHRADGPGRYRLVPGTGQTHQLRVHMSALGVP 257 Query 242 IMGDPLYPNVIS-VAAHDFSTPLQLLAQRIEFDDPLTGSHREFASTRTLTG-ATLPTWSA 299 I+GDPLYP V + V A DF PLQLLA+ +EF DP+TG F S R L ++ W+A Sbjct 258 ILGDPLYPEVTAPVPAGDFRRPLQLLARVLEFTDPVTGVEHRFTSRRELAAWSSYEEWAA 317 Query 300 A 300 Sbjct 318 G 318 >gi|269796147|ref|YP_003315602.1| 23S RNA-specific pseudouridylate synthase [Sanguibacter keddieii DSM 10542] gi|269098332|gb|ACZ22768.1| 23S RNA-specific pseudouridylate synthase [Sanguibacter keddieii DSM 10542] Length=303 Score = 271 bits (692), Expect = 1e-70, Method: Compositional matrix adjust. Identities = 160/295 (55%), Positives = 195/295 (67%), Gaps = 17/295 (5%) Query 12 VHDVLGPVRVRLLGG----SVLAELTARFGVAA---RAKVLAGEVVDDDGAVVDSGTVLP 64 + D L PVR++L G +VLA L ARF A R KV AGEVVD+ G + Sbjct 1 MRDGLNPVRLQLPHGAEAATVLAYLVARFPTDAERMREKVAAGEVVDEIGRSLGPDAPYV 60 Query 65 PGSVVHLYRDLPDEVPVPFDVPVLHQDADIVVVDKPHFLATMPRGRHVAQTALVRLRREL 124 G++V+LYRD E VPF++ VLH D D++V+DKPHFLA+ PRG +V ++A+VRLRR+L Sbjct 61 GGTLVYLYRDAAPEPRVPFEIDVLHHDDDLLVIDKPHFLASTPRGAYVVESAVVRLRRDL 120 Query 125 GLPELSPAHRLDRLTAGVLLFTTRREVRGSYQTMFARGLVRKTYLARAPVAPGLALPRLV 184 GLPE+SPAHRLDR+TAGVL+ TTRREVRG+YQ +FA + KTY A A V P L LPR V Sbjct 121 GLPEISPAHRLDRITAGVLVLTTRREVRGAYQQLFASRTIHKTYEAVARVDPRLDLPRTV 180 Query 185 RSRIVKRRGHLQAVCEPGVPNAETLVERI-----ARD-----GLYRLTPTTGRTHQLRVH 234 RSRIVK G L A PG PNAE+ V A D G Y L P TG+THQLR+H Sbjct 181 RSRIVKEHGTLVAQEVPGEPNAESRVSLAEVAPGAGDGGEALGRYVLEPHTGKTHQLRLH 240 Query 235 MAALGIPIMGDPLYPNVISVAAHDFSTPLQLLAQRIEFDDPLTGSHREFASTRTL 289 MA+LG+PI+ D YP VA D+S PLQLLA+ I F DPL+G R F S R L Sbjct 241 MASLGLPILNDNFYPRFYDVAPDDYSAPLQLLARSISFTDPLSGEPRTFTSRRAL 295 >gi|300785329|ref|YP_003765620.1| RNA pseudouridylate synthase [Amycolatopsis mediterranei U32] gi|299794843|gb|ADJ45218.1| putative RNA pseudouridylate synthase [Amycolatopsis mediterranei U32] gi|340526773|gb|AEK41978.1| RNA pseudouridylate synthase [Amycolatopsis mediterranei S699] Length=311 Score = 270 bits (691), Expect = 1e-70, Method: Compositional matrix adjust. Identities = 154/294 (53%), Positives = 193/294 (66%), Gaps = 10/294 (3%) Query 16 LGPVRVRLLGG---SVLAELTARFGVAARAKV---LAGEVVDDDGAVVDSGTVLPPGSVV 69 L P R++L G ++LA L R A ++ L E + + T PGS + Sbjct 15 LDPARLKLPDGEWPTLLAHLVDRLPRVAPDRIEEMLREERIHGTDGPLGVDTPYAPGSFI 74 Query 70 HLYRDLPDEVPVPFDVPVLHQDADIVVVDKPHFLATMPRGRHVAQTALVRLRRELGLPEL 129 +RDLPDEVPVPF + V+H+D ++VVDKPHFLAT+PRG+H+ +TALVRLRREL LP+L Sbjct 75 WFHRDLPDEVPVPFAIDVVHRDEHLLVVDKPHFLATIPRGQHILETALVRLRRELDLPQL 134 Query 130 SPAHRLDRLTAGVLLFTTRREVRGSYQTMFARGLVRKTYLARAPVAPGLALPRLVRSRIV 189 SPAHRLDR+TAG+++F E RG YQT+F V K Y A AP P L LPR VRSRIV Sbjct 135 SPAHRLDRVTAGLVMFVITPESRGKYQTLFRDRRVHKEYEAIAPHDPALTLPRTVRSRIV 194 Query 190 KRRGHLQAVCEPGVPNAET---LVERIARDGLYRLTPTTGRTHQLRVHMAALGIPIMGDP 246 K RG L A PG PNAET L+E A G YRL P TGRTHQLR+H++ LG+PI+GD Sbjct 195 KERGVLAAQEVPGEPNAETYVDLLEHRAGLGRYRLVPATGRTHQLRLHLSGLGVPILGDD 254 Query 247 LYPNVISVAAHDFSTPLQLLAQRIEFDDPLTGSHREFASTRTLTGATLP-TWSA 299 YP + DF+ PLQLLA+ ++FDDPLTG+HR F S R L+ P W+A Sbjct 255 FYPQLREKPLGDFTKPLQLLAKVLDFDDPLTGAHRRFTSARRLSAWDDPEAWAA 308 >gi|226360008|ref|YP_002777786.1| pseudouridine synthase [Rhodococcus opacus B4] gi|226238493|dbj|BAH48841.1| putative pseudouridine synthase [Rhodococcus opacus B4] Length=297 Score = 269 bits (687), Expect = 4e-70, Method: Compositional matrix adjust. Identities = 155/290 (54%), Positives = 191/290 (66%), Gaps = 10/290 (3%) Query 10 LSVHDVLGPVRVRL---LGGSVLAELTARFGVAARAKVL----AGEVVDDDGAVVDSGTV 62 L V LGP R+R+ LG +AE RA L AG+VVD+ G VVD GT Sbjct 6 LPVRGGLGPDRIRMPAGLGARTVAEFLVDTYPDERAHWLSLIDAGDVVDEHGRVVDRGTR 65 Query 63 LPPGSVVHLYRDLPDEVPVPFDVPVLHQDADIVVVDKPHFLATMPRGRHVAQTALVRLRR 122 P V+ YRD E+PVPF++ VLH+D +VV+DKPHFLAT+PRG H+ +TA+VRLRR Sbjct 66 YAPTRFVYFYRDPAPEIPVPFEIDVLHRDDHLVVIDKPHFLATIPRGAHITETAVVRLRR 125 Query 123 ELGLPELSPAHRLDRLTAGVLLFTTRREVRGSYQTMFARGLVRKTYLARAPVAPGLALPR 182 L LP+L+PAHRLDR+TAGVL+F R E R +YQ +F V K Y A A P L PR Sbjct 126 ALDLPDLTPAHRLDRMTAGVLVFLIRPEDRRAYQELFVSQQVTKEYEAVAGHDPALEFPR 185 Query 183 LVRSRIVKRRGHLQAVCEPGVPNAETLVERI-ARDG--LYRLTPTTGRTHQLRVHMAALG 239 +RSRIVK G + A EPG PN+ET+V+ I +RDG YRL P TGRTHQLR+HM++LG Sbjct 186 TIRSRIVKEHGIMTATEEPGEPNSETVVDLIESRDGRARYRLLPKTGRTHQLRLHMSSLG 245 Query 240 IPIMGDPLYPNVISVAAHDFSTPLQLLAQRIEFDDPLTGSHREFASTRTL 289 +PI GD YP+ DFSTPL+LLA+ IEF DP +G R F S RTL Sbjct 246 LPIEGDNYYPDFRRSEPGDFSTPLRLLARAIEFTDPRSGRVRRFESRRTL 295 >gi|294628458|ref|ZP_06707018.1| RNA pseudouridylate synthase [Streptomyces sp. e14] gi|292831791|gb|EFF90140.1| RNA pseudouridylate synthase [Streptomyces sp. e14] Length=324 Score = 268 bits (684), Expect = 1e-69, Method: Compositional matrix adjust. Identities = 165/294 (57%), Positives = 186/294 (64%), Gaps = 14/294 (4%) Query 18 PVRVRL----LGGSVLAELTARFGVAARAKV----LAGEVVDDDGAVVDSGTVLPPGSVV 69 PVRVRL +V L R AA V AG +V DG V PG V Sbjct 27 PVRVRLPAEGAWATVREHLVERLSGAAPGVVEEMFAAGRIVAADGRAVPPDAPYEPGMFV 86 Query 70 HLYRDLPDEVPVPFDVPVLHQDADIVVVDKPHFLATMPRGRHVAQTALVRLRRELGLPEL 129 +R+LP E PVPF + V+H+D IVVVDKPHFLAT PRG HV +TAL RLRREL LP L Sbjct 87 WFHRELPAETPVPFPLVVVHRDEHIVVVDKPHFLATTPRGSHVTETALARLRRELDLPTL 146 Query 130 SPAHRLDRLTAGVLLFTTRREVRGSYQTMFARGLVRKTYLARAPVAPGLALPRLVRSRIV 189 AHRLDRLTAG++LFT R E RG+YQT+F VRK Y A AP P LALPR VRSRIV Sbjct 147 GAAHRLDRLTAGLVLFTVRPEERGAYQTLFRDRRVRKEYEAVAPYDPDLALPRTVRSRIV 206 Query 190 KRRGHLQAVCEPGVPNAETLVERIAR----DGLYRLTPTTGRTHQLRVHMAALGIPIMGD 245 K RG L A PG PNA T VE + R YRLTP TG+THQLRVHM ALG+PI+GD Sbjct 207 KERGVLTAEEVPGEPNAVTDVELVGRRPGGPARYRLTPRTGQTHQLRVHMNALGVPILGD 266 Query 246 PLYPNVISVA-AHDFSTPLQLLAQRIEFDDPLTGSHREFASTRTLTGATLP-TW 297 PLYP V DFS PLQLLA+ +EF DP+TG+ F S RTL + P TW Sbjct 267 PLYPAVTPDGPPGDFSRPLQLLARALEFTDPVTGAEHRFRSGRTLQAWSAPETW 320 >gi|343926401|ref|ZP_08765906.1| putative pseudouridine synthase [Gordonia alkanivorans NBRC 16433] gi|343763639|dbj|GAA12832.1| putative pseudouridine synthase [Gordonia alkanivorans NBRC 16433] Length=288 Score = 267 bits (682), Expect = 2e-69, Method: Compositional matrix adjust. Identities = 150/258 (59%), Positives = 178/258 (69%), Gaps = 8/258 (3%) Query 42 AKVLAGEVVDDDGAVVDSGTVLPPGSVVHLYRDLPDEVPVPFDVPVLHQDADIVVVDKPH 101 A+ AGE+VD DG VD ++LYRDLPDEVP+PFDVPVL++D +IVVVDKPH Sbjct 31 ARAAAGEIVDADGQPVDLDAPSRVNVSLYLYRDLPDEVPIPFDVPVLYRDENIVVVDKPH 90 Query 102 FLATMPRGRHVAQTALVRLRRELGLPELSPAHRLDRLTAGVLLFTTRREVRGSYQTMFAR 161 FL+TMPRGRHV QTALVRLRRELG +SPAHRLDRLTAGVLLFT R EVR +Y +FA Sbjct 91 FLSTMPRGRHVTQTALVRLRRELGSDTISPAHRLDRLTAGVLLFTLRPEVRAAYHDLFAS 150 Query 162 GLVRKTYLARAPVAPGLALPRLVRSRIVKRRGHLQAVCEPGVPNA---ETLVERIARDGL 218 L RK Y A APV L VR RI K G L+A G NA TLVE+ R G+ Sbjct 151 RLARKEYRALAPVDERLTETVTVRDRIEKTAGDLRARVVDGPVNAISDVTLVEQTDRGGV 210 Query 219 YRLTPTTGRTHQLRVHMAALGIPIMGDPLYPNVISVAAH-----DFSTPLQLLAQRIEFD 273 YRL P TGRTHQLR+HM++LG+PI+ DPLYP+V A DFS+PL+L+A +EF Sbjct 211 YRLVPHTGRTHQLRLHMSSLGVPIVDDPLYPDVRPELAERADHGDFSSPLRLVAHALEFT 270 Query 274 DPLTGSHREFASTRTLTG 291 DPL G+ R F S R++ Sbjct 271 DPLDGTERRFVSRRSVVS 288 >gi|258650803|ref|YP_003199959.1| pseudouridine synthase [Nakamurella multipartita DSM 44233] gi|258554028|gb|ACV76970.1| pseudouridine synthase [Nakamurella multipartita DSM 44233] Length=299 Score = 265 bits (677), Expect = 7e-69, Method: Compositional matrix adjust. Identities = 154/278 (56%), Positives = 185/278 (67%), Gaps = 9/278 (3%) Query 10 LSVHDVLGPVRVRLL---GGSVLAELTARFGVAA---RAKVLAGEVVDDDGAVVDSGTVL 63 L V D L P R+RL G+V+ L RF A R KV AGEVVD +G VVD T L Sbjct 6 LPVRDGLNPSRIRLPDEGSGTVVEYLLERFAADATRVREKVDAGEVVDGEGRVVDPSTPL 65 Query 64 PPGSVVHLYRDLPDEVPVPFDVPVLHQDADIVVVDKPHFLATMPRGRHVAQTALVRLRRE 123 V LYRD E VPF++ +LH+D+D++VVDKPHFLATMPRG H+ ++ALVRLRRE Sbjct 66 TSSQWVFLYRDPAPEPRVPFEIEILHRDSDLLVVDKPHFLATMPRGLHIVESALVRLRRE 125 Query 124 LGLPELSPAHRLDRLTAGVLLFTTRREVRGSYQTMFARGLVRKTYLARAPVAPGLALPRL 183 L LPELSP HRLDR+TAGVL+F+ R RG+YQT+FA+ V K Y A A L LP Sbjct 126 LDLPELSPIHRLDRVTAGVLVFSLRPANRGAYQTLFAQRKVTKYYEAVAGHRADLTLPTT 185 Query 184 VRSRIVKRRGHLQAVCEPGVPNAETLVERIARDG---LYRLTPTTGRTHQLRVHMAALGI 240 V SRIVK RG A PG PNA T+VER+A G LY L P TG+ HQLR+HM +LG+ Sbjct 186 VESRIVKFRGTPTAQQVPGEPNARTVVERLAARGERALYGLHPHTGKVHQLRLHMTSLGV 245 Query 241 PIMGDPLYPNVISVAAHDFSTPLQLLAQRIEFDDPLTG 278 PI+GD YP ++ D+S PLQLLA+ IEF DP TG Sbjct 246 PIVGDNFYPTLLDTPRDDYSDPLQLLARSIEFPDPFTG 283 >gi|291450450|ref|ZP_06589840.1| ribosomal pseudouridine synthase [Streptomyces albus J1074] gi|291353399|gb|EFE80301.1| ribosomal pseudouridine synthase [Streptomyces albus J1074] Length=318 Score = 265 bits (676), Expect = 9e-69, Method: Compositional matrix adjust. Identities = 164/294 (56%), Positives = 189/294 (65%), Gaps = 10/294 (3%) Query 10 LSVHDVLGPVRVRL-LGG---SVLAELTARFGVAA---RAKVLAGEVVDDDGAVVDSGTV 62 L D +GPVRVRL L G +V L R VAA A GEVV DG V + Sbjct 12 LPQRDGIGPVRVRLPLEGPWATVRDHLVERLPVAAAEVDALFAGGEVVTGDGRPVAADAP 71 Query 63 LPPGSVVHLYRDLPDEVPVPFDVPVLHQDADIVVVDKPHFLATMPRGRHVAQTALVRLRR 122 PG V +R EVP P+ VL +D +VVVDKPHFLAT PRGRHV QTAL LR Sbjct 72 YVPGGQVWFHRRRAAEVPAPYPPVVLFRDEHLVVVDKPHFLATTPRGRHVTQTALALLRT 131 Query 123 ELGLPELSPAHRLDRLTAGVLLFTTRREVRGSYQTMFARGLVRKTYLARAPVAPGLALPR 182 L LPELSPAHRLDRLTAG++L T R R +YQ +F+ LVRK Y A A PGLALPR Sbjct 132 RLELPELSPAHRLDRLTAGLVLLTVRPAERAAYQRLFSDRLVRKEYEAVAGYDPGLALPR 191 Query 183 LVRSRIVKRRGHLQAVCEPGVPNAETLVERIARDGL---YRLTPTTGRTHQLRVHMAALG 239 VRSRIVK RG + A PG PNAET VE +A G YRL P TGRTHQLRVH+ +LG Sbjct 192 TVRSRIVKERGVIAAQEVPGEPNAETRVELLAHRGTLGRYRLLPHTGRTHQLRVHLNSLG 251 Query 240 IPIMGDPLYPNVISVAAHDFSTPLQLLAQRIEFDDPLTGSHREFASTRTLTGAT 293 +PI+GDP+YP++ A DF PLQLLA+ +EF DP+TG+ R F STR LT T Sbjct 252 VPILGDPVYPHLTDPAPDDFRRPLQLLARTVEFTDPVTGAARHFTSTRRLTAWT 305 >gi|331697825|ref|YP_004334064.1| pseudouridine synthase [Pseudonocardia dioxanivorans CB1190] gi|326952514|gb|AEA26211.1| pseudouridine synthase [Pseudonocardia dioxanivorans CB1190] Length=309 Score = 262 bits (670), Expect = 4e-68, Method: Compositional matrix adjust. Identities = 142/230 (62%), Positives = 168/230 (74%), Gaps = 3/230 (1%) Query 65 PGSVVHLYRDLPDEVPVPFDVPVLHQDADIVVVDKPHFLATMPRGRHVAQTALVRLRREL 124 P + V L+RDLPDE PVPF + V+H+D ++VVDKPHFL+T+PRGRHV +TALVRLRR+L Sbjct 71 PETFVWLHRDLPDETPVPFPIHVVHRDEHLLVVDKPHFLSTIPRGRHVVETALVRLRRDL 130 Query 125 GLPELSPAHRLDRLTAGVLLFTTRREVRGSYQTMFARGLVRKTYLARAPVAPGLALPRLV 184 LPELSPAHRLDR+TAG+L+F RRE RG+YQTMF V KTY A AP P L LPR V Sbjct 131 DLPELSPAHRLDRVTAGLLMFVVRREDRGAYQTMFRDRRVAKTYEAIAPHDPALLLPRTV 190 Query 185 RSRIVKRRGHLQAVCEPGVPNAETLVERIA-RDGL--YRLTPTTGRTHQLRVHMAALGIP 241 SRIVK RG + A G PNAET VE + RDGL YRLTP TGRTHQLR+HMAAL +P Sbjct 191 TSRIVKERGIIVAREVDGPPNAETYVELVEHRDGLGRYRLTPATGRTHQLRLHMAALNVP 250 Query 242 IMGDPLYPNVISVAAHDFSTPLQLLAQRIEFDDPLTGSHREFASTRTLTG 291 I+GD YP + D++ PLQLLA+ + F DPLTG +R F ST L Sbjct 251 ILGDHFYPELHDKPLDDYTRPLQLLARTLAFTDPLTGENRRFTSTLALQA 300 >gi|302561569|ref|ZP_07313911.1| pseudouridylate synthase [Streptomyces griseoflavus Tu4000] gi|302479187|gb|EFL42280.1| pseudouridylate synthase [Streptomyces griseoflavus Tu4000] Length=299 Score = 262 bits (670), Expect = 5e-68, Method: Compositional matrix adjust. Identities = 162/299 (55%), Positives = 188/299 (63%), Gaps = 15/299 (5%) Query 16 LGPVRVRLLGGS--------VLAELTARFGVAARAKVLAGEVVDDDGAVVDSGTVLPPGS 67 + PVRVRL G ++ L+A GV G +V DG V + T PG Sbjct 1 MDPVRVRLPAGGQGATVRDHLVLRLSAGPGVVD-GMFAEGLIVGADGRAVPAETPYEPGM 59 Query 68 VVHLYRDLPDEVPVPFDVPVLHQDADIVVVDKPHFLATMPRGRHVAQTALVRLRRELGLP 127 V +R+LP EVPVPF + V+H+D IVV DKPHFLAT PRG HV QTAL RLRREL +P Sbjct 60 FVWFHRELPAEVPVPFPLEVVHRDEHIVVADKPHFLATTPRGSHVTQTALARLRRELDIP 119 Query 128 ELSPAHRLDRLTAGVLLFTTRREVRGSYQTMFARGLVRKTYLARAPVAPGLALPRLVRSR 187 EL AHRLDRLTAG++LFT R RG+YQT+F LVRK Y A AP P L LPR VRSR Sbjct 120 ELGAAHRLDRLTAGLVLFTVRPGERGAYQTLFRDRLVRKEYEAVAPYDPELVLPRTVRSR 179 Query 188 IVKRRGHLQAVCEPGVPNAETLVERIAR--DG--LYRLTPTTGRTHQLRVHMAALGIPIM 243 IVK RG L A G PNA T VE R DG YRL P TG+THQLRVHM LG+PI+ Sbjct 180 IVKERGVLTAREVAGEPNALTRVEIAERRSDGPARYRLVPGTGQTHQLRVHMNGLGVPIL 239 Query 244 GDPLYPNVISVA-AHDFSTPLQLLAQRIEFDDPLTGSHREFASTRTLTG-ATLPTWSAA 300 GDPLYP V A DF PLQLLA+ +EF DP+TG+ F+S R L A+ W+A Sbjct 240 GDPLYPEVTGPGPAGDFRRPLQLLARTLEFTDPVTGAEHRFSSGRALAAWASYEDWAAG 298 >gi|297195328|ref|ZP_06912726.1| ribosomal pseudouridine synthase [Streptomyces pristinaespiralis ATCC 25486] gi|197719590|gb|EDY63498.1| ribosomal pseudouridine synthase [Streptomyces pristinaespiralis ATCC 25486] Length=314 Score = 262 bits (669), Expect = 5e-68, Method: Compositional matrix adjust. Identities = 155/286 (55%), Positives = 188/286 (66%), Gaps = 15/286 (5%) Query 14 DVLGPVRVRL------LGGSVLAELTARFGVAARAK-----VLAGEVVDDDGAVVDSGTV 62 D + PVR+RL + +V L AR+G A A+ V G VD +G V + Sbjct 17 DGIDPVRLRLPEDPDGVWPTVRDHLLARYGAAIGAERVDAMVREGRFVDAEGPVTADESY 76 Query 63 LPPGSVVHLYRDLPDEVPVPFDVPVLHQDADIVVVDKPHFLATMPRGRHVAQTALVRLRR 122 G + +RD P E VPF++ V+H+D IV+ DKPHFLATMPRG HV +TAL R+RR Sbjct 77 TA-GRDLWFHRDFPAEERVPFEIGVVHRDEHIVIADKPHFLATMPRGSHVRETALARMRR 135 Query 123 ELGLPELSPAHRLDRLTAGVLLFTTRREVRGSYQTMFARGLVRKTYLARAPVAPGLALPR 182 L LP L PAHRLDRLTAG++LF R RG+YQTMF LVRK Y A AP P +ALPR Sbjct 136 GLDLPSLQPAHRLDRLTAGLVLFVVRPGDRGAYQTMFRDRLVRKEYEAVAPYDPAVALPR 195 Query 183 LVRSRIVKRRGHLQAVCEPGVPNAETLVERIA-RDGL--YRLTPTTGRTHQLRVHMAALG 239 VRSRIVK RG L AV EPG PN+E+ +E + RDGL YRL P TGRTHQLRVHM ALG Sbjct 196 TVRSRIVKERGVLTAVEEPGEPNSESRIELLEVRDGLGRYRLLPATGRTHQLRVHMNALG 255 Query 240 IPIMGDPLYPNVISVAAHDFSTPLQLLAQRIEFDDPLTGSHREFAS 285 +PI+ DPLYP V+ D++ PLQLLA+ +EF DP+TG R F S Sbjct 256 LPILHDPLYPVVLPDGPDDYARPLQLLARALEFTDPVTGEPRSFRS 301 >gi|291443564|ref|ZP_06582954.1| ribosomal pseudouridine synthase [Streptomyces roseosporus NRRL 15998] gi|291346511|gb|EFE73415.1| ribosomal pseudouridine synthase [Streptomyces roseosporus NRRL 15998] Length=312 Score = 261 bits (667), Expect = 1e-67, Method: Compositional matrix adjust. Identities = 160/296 (55%), Positives = 186/296 (63%), Gaps = 15/296 (5%) Query 10 LSVHDVLGPVRVRL------LGGSVLAELTARFGVAARAKVLAG-----EVVDDDGAVVD 58 L D + VRVRL SV L RFG A A +AG V DG V Sbjct 12 LPQRDGIDAVRVRLPEDREGRWASVGEHLVDRFGGAIGADRVAGMLDAGRFVGADGVAVR 71 Query 59 SGTVLPPGSVVHLYRDLPDEVPVPFDVPVLHQDADIVVVDKPHFLATMPRGRHVAQTALV 118 G + +RD E PVPF V V+++D IVV DKPHFLATMPRGRH+ +TA+ Sbjct 72 GSEPYATGRCLWFHRDFAAEEPVPFPVGVVYRDERIVVADKPHFLATMPRGRHITETAVA 131 Query 119 RLRRELGLPELSPAHRLDRLTAGVLLFTTRREVRGSYQTMFARGLVRKTYLARAPVAPGL 178 RLRREL LP L PAHRLDRLTAG++LF R + RG+YQT+F VRK Y A AP PG+ Sbjct 132 RLRRELDLPVLQPAHRLDRLTAGLVLFVVRSQDRGAYQTLFRDRRVRKEYEAVAPYDPGV 191 Query 179 ALPRLVRSRIVKRRGHLQAVCEPGVPNAETLVERIARDGL---YRLTPTTGRTHQLRVHM 235 ALPR VRSRIVK RG L A EPG N+E+ VE + R G YRL P TGRTHQLRVHM Sbjct 192 ALPRTVRSRIVKERGVLAAREEPGEANSESHVELVERRGALGRYRLVPATGRTHQLRVHM 251 Query 236 AALGIPIMGDPLYPNVISVA-AHDFSTPLQLLAQRIEFDDPLTGSHREFASTRTLT 290 ALG+PI+ DPLYP V + A A DFS PLQLLA+ +EF DP+ G R F ST L+ Sbjct 252 NALGLPIVHDPLYPVVAAEASADDFSRPLQLLARVLEFTDPVGGEPRRFESTLRLS 307 Lambda K H 0.323 0.139 0.414 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 515090394876 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40