BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv3313c Length=365 Score E Sequences producing significant alignments: (Bits) Value gi|308377299|ref|ZP_07441791.2| adenosine deaminase add [Mycobac... 742 0.0 gi|15610449|ref|NP_217830.1| adenosine deaminase [Mycobacterium ... 742 0.0 gi|340628297|ref|YP_004746749.1| putative adenosine deaminase AD... 741 0.0 gi|306782366|ref|ZP_07420703.1| adenosine deaminase add [Mycobac... 739 0.0 gi|240169122|ref|ZP_04747781.1| adenosine deaminase [Mycobacteri... 663 0.0 gi|15827296|ref|NP_301559.1| adenosine deaminase [Mycobacterium ... 643 0.0 gi|118617049|ref|YP_905381.1| adenosine deaminase [Mycobacterium... 642 0.0 gi|183981228|ref|YP_001849519.1| adenosine deaminase Add [Mycoba... 642 0.0 gi|254820237|ref|ZP_05225238.1| adenosine deaminase [Mycobacteri... 636 2e-180 gi|342861539|ref|ZP_08718186.1| adenosine deaminase [Mycobacteri... 635 3e-180 gi|336459596|gb|EGO38531.1| adenosine deaminase [Mycobacterium a... 633 1e-179 gi|41409536|ref|NP_962372.1| adenosine deaminase [Mycobacterium ... 632 4e-179 gi|296168864|ref|ZP_06850536.1| adenosine deaminase [Mycobacteri... 625 2e-177 gi|333991780|ref|YP_004524394.1| adenosine deaminase Add [Mycoba... 619 2e-175 gi|118467725|ref|YP_886052.1| adenosine deaminase [Mycobacterium... 619 2e-175 gi|108798204|ref|YP_638401.1| adenosine deaminase [Mycobacterium... 609 2e-172 gi|126433861|ref|YP_001069552.1| adenosine deaminase [Mycobacter... 608 4e-172 gi|120402598|ref|YP_952427.1| adenosine deaminase [Mycobacterium... 607 1e-171 gi|467172|gb|AAA17330.1| add [Mycobacterium leprae] 601 5e-170 gi|145225419|ref|YP_001136097.1| adenosine deaminase [Mycobacter... 587 7e-166 gi|169630749|ref|YP_001704398.1| adenosine deaminase [Mycobacter... 572 3e-161 gi|226305535|ref|YP_002765495.1| adenosine deaminase [Rhodococcu... 556 2e-156 gi|229489626|ref|ZP_04383489.1| adenosine deaminase [Rhodococcus... 554 9e-156 gi|111023214|ref|YP_706186.1| adenosine deaminase [Rhodococcus j... 540 1e-151 gi|226365719|ref|YP_002783502.1| adenosine deaminase [Rhodococcu... 538 4e-151 gi|312140768|ref|YP_004008104.1| adenosine deaminase [Rhodococcu... 537 1e-150 gi|325675592|ref|ZP_08155276.1| adenosine deaminase [Rhodococcus... 536 3e-150 gi|296138705|ref|YP_003645948.1| adenosine deaminase [Tsukamurel... 530 2e-148 gi|54022920|ref|YP_117162.1| adenosine deaminase [Nocardia farci... 524 1e-146 gi|262201724|ref|YP_003272932.1| adenosine deaminase [Gordonia b... 520 1e-145 gi|343926659|ref|ZP_08766157.1| adenosine deaminase [Gordonia al... 514 1e-143 gi|333921527|ref|YP_004495108.1| adenosine deaminase [Amycolicic... 512 4e-143 gi|326381953|ref|ZP_08203646.1| adenosine deaminase [Gordonia ne... 508 6e-142 gi|271962824|ref|YP_003337020.1| adenosine deaminase [Streptospo... 506 2e-141 gi|296268670|ref|YP_003651302.1| adenosine deaminase [Thermobisp... 501 1e-139 gi|297201973|ref|ZP_06919370.1| adenosine deaminase [Streptomyce... 492 4e-137 gi|329935635|ref|ZP_08285442.1| adenosine deaminase [Streptomyce... 492 4e-137 gi|302865289|ref|YP_003833926.1| adenosine deaminase [Micromonos... 491 8e-137 gi|21223275|ref|NP_629054.1| adenosine deaminase [Streptomyces c... 490 1e-136 gi|315501833|ref|YP_004080720.1| adenosine deaminase [Micromonos... 490 2e-136 gi|312199932|ref|YP_004019993.1| adenosine deaminase [Frankia sp... 489 2e-136 gi|302558808|ref|ZP_07311150.1| adenosine deaminase [Streptomyce... 489 2e-136 gi|291437633|ref|ZP_06577023.1| adenosine deaminase [Streptomyce... 488 5e-136 gi|145593373|ref|YP_001157670.1| adenosine deaminase [Salinispor... 488 6e-136 gi|294631077|ref|ZP_06709637.1| adenosine deaminase [Streptomyce... 488 7e-136 gi|336177055|ref|YP_004582430.1| adenosine deaminase [Frankia sy... 488 7e-136 gi|291298884|ref|YP_003510162.1| adenosine deaminase [Stackebran... 486 2e-135 gi|29829900|ref|NP_824534.1| adenosine deaminase [Streptomyces a... 486 2e-135 gi|254389917|ref|ZP_05005140.1| adenosine deaminase [Streptomyce... 486 2e-135 gi|302536426|ref|ZP_07288768.1| adenosine deaminase [Streptomyce... 486 3e-135 >gi|308377299|ref|ZP_07441791.2| adenosine deaminase add [Mycobacterium tuberculosis SUMu008] gi|308348425|gb|EFP37276.1| adenosine deaminase add [Mycobacterium tuberculosis SUMu008] Length=366 Score = 742 bits (1916), Expect = 0.0, Method: Compositional matrix adjust. Identities = 365/365 (100%), Positives = 365/365 (100%), Gaps = 0/365 (0%) Query 1 MTAAPTLQTIRLAPKALLHDHLDGGLRPATVLDIAGQVGYDDLPATDVDALASWFRTQSH 60 MTAAPTLQTIRLAPKALLHDHLDGGLRPATVLDIAGQVGYDDLPATDVDALASWFRTQSH Sbjct 2 MTAAPTLQTIRLAPKALLHDHLDGGLRPATVLDIAGQVGYDDLPATDVDALASWFRTQSH 61 Query 61 SGSLERYLEPFSHTVAVMQTPEALYRVAFECAQDLAADSVVYAEVRFAPELHISCGLSFD 120 SGSLERYLEPFSHTVAVMQTPEALYRVAFECAQDLAADSVVYAEVRFAPELHISCGLSFD Sbjct 62 SGSLERYLEPFSHTVAVMQTPEALYRVAFECAQDLAADSVVYAEVRFAPELHISCGLSFD 121 Query 121 DVVDTVLTGFAAGEKACAADGQPITVRCLVTAMRHAAMSREIAELAIRFRDKGVVGFDIA 180 DVVDTVLTGFAAGEKACAADGQPITVRCLVTAMRHAAMSREIAELAIRFRDKGVVGFDIA Sbjct 122 DVVDTVLTGFAAGEKACAADGQPITVRCLVTAMRHAAMSREIAELAIRFRDKGVVGFDIA 181 Query 181 GAEAGHPPTRHLDAFEYMRDHNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDI 240 GAEAGHPPTRHLDAFEYMRDHNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDI Sbjct 182 GAEAGHPPTRHLDAFEYMRDHNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDI 241 Query 241 DVDADGGFQLGRLAAILRDKRIPLELCPSSNVQTGAVASIAEHPFDLLARARFRVTVNTD 300 DVDADGGFQLGRLAAILRDKRIPLELCPSSNVQTGAVASIAEHPFDLLARARFRVTVNTD Sbjct 242 DVDADGGFQLGRLAAILRDKRIPLELCPSSNVQTGAVASIAEHPFDLLARARFRVTVNTD 301 Query 301 NRLMSDTSMSLEMHRLVEAFGYGWSDLARFTVNAMKSAFIPFDQRLAIIDEVIKPRFAAL 360 NRLMSDTSMSLEMHRLVEAFGYGWSDLARFTVNAMKSAFIPFDQRLAIIDEVIKPRFAAL Sbjct 302 NRLMSDTSMSLEMHRLVEAFGYGWSDLARFTVNAMKSAFIPFDQRLAIIDEVIKPRFAAL 361 Query 361 MGHSE 365 MGHSE Sbjct 362 MGHSE 366 >gi|15610449|ref|NP_217830.1| adenosine deaminase [Mycobacterium tuberculosis H37Rv] gi|31794494|ref|NP_856987.1| adenosine deaminase [Mycobacterium bovis AF2122/97] gi|121639237|ref|YP_979461.1| adenosine deaminase [Mycobacterium bovis BCG str. Pasteur 1173P2] 77 more sequence titles Length=365 Score = 742 bits (1915), Expect = 0.0, Method: Compositional matrix adjust. Identities = 365/365 (100%), Positives = 365/365 (100%), Gaps = 0/365 (0%) Query 1 MTAAPTLQTIRLAPKALLHDHLDGGLRPATVLDIAGQVGYDDLPATDVDALASWFRTQSH 60 MTAAPTLQTIRLAPKALLHDHLDGGLRPATVLDIAGQVGYDDLPATDVDALASWFRTQSH Sbjct 1 MTAAPTLQTIRLAPKALLHDHLDGGLRPATVLDIAGQVGYDDLPATDVDALASWFRTQSH 60 Query 61 SGSLERYLEPFSHTVAVMQTPEALYRVAFECAQDLAADSVVYAEVRFAPELHISCGLSFD 120 SGSLERYLEPFSHTVAVMQTPEALYRVAFECAQDLAADSVVYAEVRFAPELHISCGLSFD Sbjct 61 SGSLERYLEPFSHTVAVMQTPEALYRVAFECAQDLAADSVVYAEVRFAPELHISCGLSFD 120 Query 121 DVVDTVLTGFAAGEKACAADGQPITVRCLVTAMRHAAMSREIAELAIRFRDKGVVGFDIA 180 DVVDTVLTGFAAGEKACAADGQPITVRCLVTAMRHAAMSREIAELAIRFRDKGVVGFDIA Sbjct 121 DVVDTVLTGFAAGEKACAADGQPITVRCLVTAMRHAAMSREIAELAIRFRDKGVVGFDIA 180 Query 181 GAEAGHPPTRHLDAFEYMRDHNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDI 240 GAEAGHPPTRHLDAFEYMRDHNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDI Sbjct 181 GAEAGHPPTRHLDAFEYMRDHNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDI 240 Query 241 DVDADGGFQLGRLAAILRDKRIPLELCPSSNVQTGAVASIAEHPFDLLARARFRVTVNTD 300 DVDADGGFQLGRLAAILRDKRIPLELCPSSNVQTGAVASIAEHPFDLLARARFRVTVNTD Sbjct 241 DVDADGGFQLGRLAAILRDKRIPLELCPSSNVQTGAVASIAEHPFDLLARARFRVTVNTD 300 Query 301 NRLMSDTSMSLEMHRLVEAFGYGWSDLARFTVNAMKSAFIPFDQRLAIIDEVIKPRFAAL 360 NRLMSDTSMSLEMHRLVEAFGYGWSDLARFTVNAMKSAFIPFDQRLAIIDEVIKPRFAAL Sbjct 301 NRLMSDTSMSLEMHRLVEAFGYGWSDLARFTVNAMKSAFIPFDQRLAIIDEVIKPRFAAL 360 Query 361 MGHSE 365 MGHSE Sbjct 361 MGHSE 365 >gi|340628297|ref|YP_004746749.1| putative adenosine deaminase ADD [Mycobacterium canettii CIPT 140010059] gi|340006487|emb|CCC45670.1| putative adenosine deaminase ADD (adenosine aminohydrolase) [Mycobacterium canettii CIPT 140010059] Length=365 Score = 741 bits (1912), Expect = 0.0, Method: Compositional matrix adjust. Identities = 364/365 (99%), Positives = 365/365 (100%), Gaps = 0/365 (0%) Query 1 MTAAPTLQTIRLAPKALLHDHLDGGLRPATVLDIAGQVGYDDLPATDVDALASWFRTQSH 60 MTAAPTLQTIRLAPKALLHDHLDGGLRPATVLDIAGQVGYDDLPATDVDALASWFRTQSH Sbjct 1 MTAAPTLQTIRLAPKALLHDHLDGGLRPATVLDIAGQVGYDDLPATDVDALASWFRTQSH 60 Query 61 SGSLERYLEPFSHTVAVMQTPEALYRVAFECAQDLAADSVVYAEVRFAPELHISCGLSFD 120 SGSLERYLEPFSHTVAVMQTPEALYRVAFECAQDLAADSVVYAEVRFAPELHISCGLSFD Sbjct 61 SGSLERYLEPFSHTVAVMQTPEALYRVAFECAQDLAADSVVYAEVRFAPELHISCGLSFD 120 Query 121 DVVDTVLTGFAAGEKACAADGQPITVRCLVTAMRHAAMSREIAELAIRFRDKGVVGFDIA 180 DVVDTVLTGFAAGEKACAADGQPITVRCLVTAMRHAAMSREIAELAIRFRDKGVVGFDIA Sbjct 121 DVVDTVLTGFAAGEKACAADGQPITVRCLVTAMRHAAMSREIAELAIRFRDKGVVGFDIA 180 Query 181 GAEAGHPPTRHLDAFEYMRDHNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDI 240 GAEAGHPPTRHLDAFEYMRDHNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDI Sbjct 181 GAEAGHPPTRHLDAFEYMRDHNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDI 240 Query 241 DVDADGGFQLGRLAAILRDKRIPLELCPSSNVQTGAVASIAEHPFDLLARARFRVTVNTD 300 DVDADGGFQLGRLAAILRDKRIPLELCPSSNVQTGAV+SIAEHPFDLLARARFRVTVNTD Sbjct 241 DVDADGGFQLGRLAAILRDKRIPLELCPSSNVQTGAVSSIAEHPFDLLARARFRVTVNTD 300 Query 301 NRLMSDTSMSLEMHRLVEAFGYGWSDLARFTVNAMKSAFIPFDQRLAIIDEVIKPRFAAL 360 NRLMSDTSMSLEMHRLVEAFGYGWSDLARFTVNAMKSAFIPFDQRLAIIDEVIKPRFAAL Sbjct 301 NRLMSDTSMSLEMHRLVEAFGYGWSDLARFTVNAMKSAFIPFDQRLAIIDEVIKPRFAAL 360 Query 361 MGHSE 365 MGHSE Sbjct 361 MGHSE 365 >gi|306782366|ref|ZP_07420703.1| adenosine deaminase add [Mycobacterium tuberculosis SUMu002] gi|306790556|ref|ZP_07428878.1| adenosine deaminase add [Mycobacterium tuberculosis SUMu004] gi|306795077|ref|ZP_07433379.1| adenosine deaminase add [Mycobacterium tuberculosis SUMu005] gi|308325115|gb|EFP13966.1| adenosine deaminase add [Mycobacterium tuberculosis SUMu002] gi|308333167|gb|EFP22018.1| adenosine deaminase add [Mycobacterium tuberculosis SUMu004] gi|308336652|gb|EFP25503.1| adenosine deaminase add [Mycobacterium tuberculosis SUMu005] Length=365 Score = 739 bits (1909), Expect = 0.0, Method: Compositional matrix adjust. Identities = 364/365 (99%), Positives = 364/365 (99%), Gaps = 0/365 (0%) Query 1 MTAAPTLQTIRLAPKALLHDHLDGGLRPATVLDIAGQVGYDDLPATDVDALASWFRTQSH 60 MTAAPTLQTIRLAPKALLHDHLDGGLRPATVLDIAGQVGYDDLPATDVDALASWFRTQSH Sbjct 1 MTAAPTLQTIRLAPKALLHDHLDGGLRPATVLDIAGQVGYDDLPATDVDALASWFRTQSH 60 Query 61 SGSLERYLEPFSHTVAVMQTPEALYRVAFECAQDLAADSVVYAEVRFAPELHISCGLSFD 120 SGSLERYLEPFSHTVAVMQ PEALYRVAFECAQDLAADSVVYAEVRFAPELHISCGLSFD Sbjct 61 SGSLERYLEPFSHTVAVMQIPEALYRVAFECAQDLAADSVVYAEVRFAPELHISCGLSFD 120 Query 121 DVVDTVLTGFAAGEKACAADGQPITVRCLVTAMRHAAMSREIAELAIRFRDKGVVGFDIA 180 DVVDTVLTGFAAGEKACAADGQPITVRCLVTAMRHAAMSREIAELAIRFRDKGVVGFDIA Sbjct 121 DVVDTVLTGFAAGEKACAADGQPITVRCLVTAMRHAAMSREIAELAIRFRDKGVVGFDIA 180 Query 181 GAEAGHPPTRHLDAFEYMRDHNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDI 240 GAEAGHPPTRHLDAFEYMRDHNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDI Sbjct 181 GAEAGHPPTRHLDAFEYMRDHNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDI 240 Query 241 DVDADGGFQLGRLAAILRDKRIPLELCPSSNVQTGAVASIAEHPFDLLARARFRVTVNTD 300 DVDADGGFQLGRLAAILRDKRIPLELCPSSNVQTGAVASIAEHPFDLLARARFRVTVNTD Sbjct 241 DVDADGGFQLGRLAAILRDKRIPLELCPSSNVQTGAVASIAEHPFDLLARARFRVTVNTD 300 Query 301 NRLMSDTSMSLEMHRLVEAFGYGWSDLARFTVNAMKSAFIPFDQRLAIIDEVIKPRFAAL 360 NRLMSDTSMSLEMHRLVEAFGYGWSDLARFTVNAMKSAFIPFDQRLAIIDEVIKPRFAAL Sbjct 301 NRLMSDTSMSLEMHRLVEAFGYGWSDLARFTVNAMKSAFIPFDQRLAIIDEVIKPRFAAL 360 Query 361 MGHSE 365 MGHSE Sbjct 361 MGHSE 365 >gi|240169122|ref|ZP_04747781.1| adenosine deaminase [Mycobacterium kansasii ATCC 12478] Length=362 Score = 663 bits (1711), Expect = 0.0, Method: Compositional matrix adjust. Identities = 325/362 (90%), Positives = 339/362 (94%), Gaps = 0/362 (0%) Query 1 MTAAPTLQTIRLAPKALLHDHLDGGLRPATVLDIAGQVGYDDLPATDVDALASWFRTQSH 60 MT A TL+ IR APKALLHDHLDGGLRPATVLDIAGQ+GYDDLPA DV LA+WFRT+SH Sbjct 1 MTTALTLEMIRQAPKALLHDHLDGGLRPATVLDIAGQIGYDDLPAADVATLATWFRTRSH 60 Query 61 SGSLERYLEPFSHTVAVMQTPEALYRVAFECAQDLAADSVVYAEVRFAPELHISCGLSFD 120 SGSLERYLEPFSHTVAVMQT EALYRVAFEC +DLAADSVVYAEVRFAPELHI GLSFD Sbjct 61 SGSLERYLEPFSHTVAVMQTSEALYRVAFECVEDLAADSVVYAEVRFAPELHIDRGLSFD 120 Query 121 DVVDTVLTGFAAGEKACAADGQPITVRCLVTAMRHAAMSREIAELAIRFRDKGVVGFDIA 180 +VVD VL GFA GEKACA G+ I VRCLVTAMRHAA+SREIAELAIRFRDKGVVGFDIA Sbjct 121 EVVDAVLAGFAEGEKACAGAGRSIKVRCLVTAMRHAAVSREIAELAIRFRDKGVVGFDIA 180 Query 181 GAEAGHPPTRHLDAFEYMRDHNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDI 240 GAEAGHPPTRHLDAFEYMRD+NARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDI Sbjct 181 GAEAGHPPTRHLDAFEYMRDNNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDI 240 Query 241 DVDADGGFQLGRLAAILRDKRIPLELCPSSNVQTGAVASIAEHPFDLLARARFRVTVNTD 300 DV ADGG +LGRLA+ILRDKRIPLELCPSSNVQTGAVASIAEHPFDLLARARFRVTVNTD Sbjct 241 DVGADGGVRLGRLASILRDKRIPLELCPSSNVQTGAVASIAEHPFDLLARARFRVTVNTD 300 Query 301 NRLMSDTSMSLEMHRLVEAFGYGWSDLARFTVNAMKSAFIPFDQRLAIIDEVIKPRFAAL 360 NRLMSDTSMSLEMHRLVEAFGYGWSDL RFT+NAMKSAFIPFD+RL IIDEVIKPRFA L Sbjct 301 NRLMSDTSMSLEMHRLVEAFGYGWSDLERFTINAMKSAFIPFDERLEIIDEVIKPRFAVL 360 Query 361 MG 362 +G Sbjct 361 IG 362 >gi|15827296|ref|NP_301559.1| adenosine deaminase [Mycobacterium leprae TN] gi|221229774|ref|YP_002503190.1| adenosine deaminase [Mycobacterium leprae Br4923] gi|20137229|sp|Q9CCL9.1|ADD_MYCLE RecName: Full=Adenosine deaminase; AltName: Full=Adenosine aminohydrolase gi|254802155|sp|B8ZUW8.1|ADD_MYCLB RecName: Full=Adenosine deaminase; AltName: Full=Adenosine aminohydrolase gi|13092845|emb|CAC30209.1| putative adenosine deaminase [Mycobacterium leprae] gi|219932881|emb|CAR70794.1| putative adenosine deaminase [Mycobacterium leprae Br4923] Length=362 Score = 643 bits (1658), Expect = 0.0, Method: Compositional matrix adjust. Identities = 314/356 (89%), Positives = 333/356 (94%), Gaps = 0/356 (0%) Query 7 LQTIRLAPKALLHDHLDGGLRPATVLDIAGQVGYDDLPATDVDALASWFRTQSHSGSLER 66 L+ I+ APKALLHDHLDGGLRPATVLDIAGQVGYD LPATDV++L +WFRT SHSGSLER Sbjct 7 LENIKQAPKALLHDHLDGGLRPATVLDIAGQVGYDRLPATDVESLETWFRTASHSGSLER 66 Query 67 YLEPFSHTVAVMQTPEALYRVAFECAQDLAADSVVYAEVRFAPELHISCGLSFDDVVDTV 126 YLEPFSHTVAVMQTPEAL+RVA+EC +DLAADSVVYAEVRFAPELHI GLSFD+V+ +V Sbjct 67 YLEPFSHTVAVMQTPEALHRVAYECVEDLAADSVVYAEVRFAPELHIDEGLSFDEVLASV 126 Query 127 LTGFAAGEKACAADGQPITVRCLVTAMRHAAMSREIAELAIRFRDKGVVGFDIAGAEAGH 186 L GFA GE+ACAA+G ITVRCLVTAMRHAAMSREIAELAIRFRDKGVVGFDIAGAEAGH Sbjct 127 LAGFADGERACAAEGNAITVRCLVTAMRHAAMSREIAELAIRFRDKGVVGFDIAGAEAGH 186 Query 187 PPTRHLDAFEYMRDHNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDIDVDADG 246 PPTRHLDAFEYMR +NARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDIDVD G Sbjct 187 PPTRHLDAFEYMRSNNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDIDVDPGG 246 Query 247 GFQLGRLAAILRDKRIPLELCPSSNVQTGAVASIAEHPFDLLARARFRVTVNTDNRLMSD 306 G +LG LA+ILRDKRIPLELCPSSN+QTGAVASI EHPFDLLA ARFRVTVNTDNRLMSD Sbjct 247 GIRLGPLASILRDKRIPLELCPSSNLQTGAVASITEHPFDLLAWARFRVTVNTDNRLMSD 306 Query 307 TSMSLEMHRLVEAFGYGWSDLARFTVNAMKSAFIPFDQRLAIIDEVIKPRFAALMG 362 TSMSLEMHRLVEAFGYGW DL RFT+NAMKSAFIPFDQRLAIIDEVIKPRFA L+G Sbjct 307 TSMSLEMHRLVEAFGYGWGDLERFTINAMKSAFIPFDQRLAIIDEVIKPRFAVLVG 362 >gi|118617049|ref|YP_905381.1| adenosine deaminase [Mycobacterium ulcerans Agy99] gi|166198309|sp|A0PNJ1.1|ADD_MYCUA RecName: Full=Adenosine deaminase; AltName: Full=Adenosine aminohydrolase gi|118569159|gb|ABL03910.1| adenosine deaminase Add [Mycobacterium ulcerans Agy99] Length=362 Score = 642 bits (1656), Expect = 0.0, Method: Compositional matrix adjust. Identities = 312/362 (87%), Positives = 333/362 (92%), Gaps = 0/362 (0%) Query 1 MTAAPTLQTIRLAPKALLHDHLDGGLRPATVLDIAGQVGYDDLPATDVDALASWFRTQSH 60 MT PTL IR APKALLHDHLDGGLRP TVLDIAGQVGYD LP+TD LASWFRTQSH Sbjct 1 MTDMPTLDAIRQAPKALLHDHLDGGLRPETVLDIAGQVGYDGLPSTDAGELASWFRTQSH 60 Query 61 SGSLERYLEPFSHTVAVMQTPEALYRVAFECAQDLAADSVVYAEVRFAPELHISCGLSFD 120 SGSLERYLEPFSHTVAVMQTPEALYRVA+EC +DLAAD+VVYAE+RFAPELHI+ GL+FD Sbjct 61 SGSLERYLEPFSHTVAVMQTPEALYRVAYECVEDLAADAVVYAEIRFAPELHINRGLTFD 120 Query 121 DVVDTVLTGFAAGEKACAADGQPITVRCLVTAMRHAAMSREIAELAIRFRDKGVVGFDIA 180 ++VD VL GFAAGE+ACA G PI VR LVTAMRHAAMSREIAELAIRFRDKGVVGFDIA Sbjct 121 EIVDAVLAGFAAGERACAGAGCPIKVRLLVTAMRHAAMSREIAELAIRFRDKGVVGFDIA 180 Query 181 GAEAGHPPTRHLDAFEYMRDHNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDI 240 GAEAG+PP+RHLDAFEYMRD+NARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDI Sbjct 181 GAEAGYPPSRHLDAFEYMRDNNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDI 240 Query 241 DVDADGGFQLGRLAAILRDKRIPLELCPSSNVQTGAVASIAEHPFDLLARARFRVTVNTD 300 +V DG +LGRLAAILRDKRIPLELCPSSNVQTGAVASIAEHPFDLLAR+RFRVTVNTD Sbjct 241 EVGLDGDVKLGRLAAILRDKRIPLELCPSSNVQTGAVASIAEHPFDLLARSRFRVTVNTD 300 Query 301 NRLMSDTSMSLEMHRLVEAFGYGWSDLARFTVNAMKSAFIPFDQRLAIIDEVIKPRFAAL 360 NRLMSDTSMS EM+RLVE FGYGWSD+ RFT+NAMKSAFI FD+RL IIDEVIKPRFA L Sbjct 301 NRLMSDTSMSQEMYRLVETFGYGWSDIQRFTINAMKSAFIAFDERLEIIDEVIKPRFAVL 360 Query 361 MG 362 +G Sbjct 361 IG 362 >gi|183981228|ref|YP_001849519.1| adenosine deaminase Add [Mycobacterium marinum M] gi|226710979|sp|B2HDU8.1|ADD_MYCMM RecName: Full=Adenosine deaminase; AltName: Full=Adenosine aminohydrolase gi|183174554|gb|ACC39664.1| adenosine deaminase Add [Mycobacterium marinum M] Length=362 Score = 642 bits (1655), Expect = 0.0, Method: Compositional matrix adjust. Identities = 312/362 (87%), Positives = 333/362 (92%), Gaps = 0/362 (0%) Query 1 MTAAPTLQTIRLAPKALLHDHLDGGLRPATVLDIAGQVGYDDLPATDVDALASWFRTQSH 60 MT PTL IR APKALLHDHLDGGLRP TVLDIAGQVGYD LP+TD LASWFRTQSH Sbjct 1 MTDMPTLDAIRQAPKALLHDHLDGGLRPETVLDIAGQVGYDGLPSTDAGELASWFRTQSH 60 Query 61 SGSLERYLEPFSHTVAVMQTPEALYRVAFECAQDLAADSVVYAEVRFAPELHISCGLSFD 120 SGSLERYLEPFSHTVAVMQTPEALYRVA+EC +DLAAD+VVYAE+RFAPELHI+ GL+FD Sbjct 61 SGSLERYLEPFSHTVAVMQTPEALYRVAYECVEDLAADAVVYAEIRFAPELHINQGLTFD 120 Query 121 DVVDTVLTGFAAGEKACAADGQPITVRCLVTAMRHAAMSREIAELAIRFRDKGVVGFDIA 180 ++VD VL GFAAGE+ACA G PI VR LVTAMRHAAMSREIAELAIRFRDKGVVGFDIA Sbjct 121 EIVDAVLAGFAAGERACAGAGCPIKVRLLVTAMRHAAMSREIAELAIRFRDKGVVGFDIA 180 Query 181 GAEAGHPPTRHLDAFEYMRDHNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDI 240 GAEAG+PP+RHLDAFEYMRD+NARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDI Sbjct 181 GAEAGYPPSRHLDAFEYMRDNNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDI 240 Query 241 DVDADGGFQLGRLAAILRDKRIPLELCPSSNVQTGAVASIAEHPFDLLARARFRVTVNTD 300 +V DG +LGRLAAILRDKRIPLELCPSSNVQTGAVASIAEHPFDLLAR+RFRVTVNTD Sbjct 241 EVGPDGDVKLGRLAAILRDKRIPLELCPSSNVQTGAVASIAEHPFDLLARSRFRVTVNTD 300 Query 301 NRLMSDTSMSLEMHRLVEAFGYGWSDLARFTVNAMKSAFIPFDQRLAIIDEVIKPRFAAL 360 NRLMSDTSMS EM+RLVE FGYGWSD+ RFT+NAMKSAFI FD+RL IIDEVIKPRFA L Sbjct 301 NRLMSDTSMSQEMYRLVETFGYGWSDIQRFTINAMKSAFIAFDERLEIIDEVIKPRFAVL 360 Query 361 MG 362 +G Sbjct 361 IG 362 >gi|254820237|ref|ZP_05225238.1| adenosine deaminase [Mycobacterium intracellulare ATCC 13950] Length=362 Score = 636 bits (1640), Expect = 2e-180, Method: Compositional matrix adjust. Identities = 313/362 (87%), Positives = 333/362 (92%), Gaps = 0/362 (0%) Query 1 MTAAPTLQTIRLAPKALLHDHLDGGLRPATVLDIAGQVGYDDLPATDVDALASWFRTQSH 60 MTA L+ IR APKALLHDHLDGGLRP+TVL+IAGQ GYD+LPATDVD LA+WFRT+SH Sbjct 1 MTAPLGLEQIRKAPKALLHDHLDGGLRPSTVLEIAGQTGYDELPATDVDELATWFRTRSH 60 Query 61 SGSLERYLEPFSHTVAVMQTPEALYRVAFECAQDLAADSVVYAEVRFAPELHISCGLSFD 120 SGSLERYLEPFSHTVAVMQTPEAL+RVA+EC +DLAADSVVYAEVRFAPELHI G+SFD Sbjct 61 SGSLERYLEPFSHTVAVMQTPEALHRVAYECVEDLAADSVVYAEVRFAPELHIDRGMSFD 120 Query 121 DVVDTVLTGFAAGEKACAADGQPITVRCLVTAMRHAAMSREIAELAIRFRDKGVVGFDIA 180 +VD VL GFA GEKACA G+PI VR LVTAMRHAA+SREIAELAIRFRDKGVVGFDIA Sbjct 121 AIVDAVLAGFADGEKACAGAGRPIVVRLLVTAMRHAAVSREIAELAIRFRDKGVVGFDIA 180 Query 181 GAEAGHPPTRHLDAFEYMRDHNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDI 240 GAEAG+PPTRHLDAFEYMRDHNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDI Sbjct 181 GAEAGNPPTRHLDAFEYMRDHNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDI 240 Query 241 DVDADGGFQLGRLAAILRDKRIPLELCPSSNVQTGAVASIAEHPFDLLARARFRVTVNTD 300 DV DG +LG+ AAILRDKRIPLELCPSSNVQTGAV SIAEHPFDLLARARFRVTVNTD Sbjct 241 DVLPDGQVRLGQQAAILRDKRIPLELCPSSNVQTGAVKSIAEHPFDLLARARFRVTVNTD 300 Query 301 NRLMSDTSMSLEMHRLVEAFGYGWSDLARFTVNAMKSAFIPFDQRLAIIDEVIKPRFAAL 360 NRLMSDT MS EM RLVEAFGYGWSDL RFT+NAMKSAFIPFD+RLAIIDEVIKPR+A L Sbjct 301 NRLMSDTFMSREMLRLVEAFGYGWSDLERFTINAMKSAFIPFDERLAIIDEVIKPRYAVL 360 Query 361 MG 362 +G Sbjct 361 IG 362 >gi|342861539|ref|ZP_08718186.1| adenosine deaminase [Mycobacterium colombiense CECT 3035] gi|342131028|gb|EGT84317.1| adenosine deaminase [Mycobacterium colombiense CECT 3035] Length=362 Score = 635 bits (1638), Expect = 3e-180, Method: Compositional matrix adjust. Identities = 310/362 (86%), Positives = 333/362 (92%), Gaps = 0/362 (0%) Query 1 MTAAPTLQTIRLAPKALLHDHLDGGLRPATVLDIAGQVGYDDLPATDVDALASWFRTQSH 60 MT L+ IR APKALLHDHLDGGLRP+TVLDIA QVGYD LPATDVD LA+WFRT+SH Sbjct 1 MTTPLGLEQIRKAPKALLHDHLDGGLRPSTVLDIAAQVGYDGLPATDVDELATWFRTRSH 60 Query 61 SGSLERYLEPFSHTVAVMQTPEALYRVAFECAQDLAADSVVYAEVRFAPELHISCGLSFD 120 SGSLERYLEPFSHTVAVMQTPEAL+RVAFEC +DLA DSVVYAEVRFAPELHI GLSFD Sbjct 61 SGSLERYLEPFSHTVAVMQTPEALHRVAFECVEDLAEDSVVYAEVRFAPELHIDRGLSFD 120 Query 121 DVVDTVLTGFAAGEKACAADGQPITVRCLVTAMRHAAMSREIAELAIRFRDKGVVGFDIA 180 ++V+ VL GFA GEKACAA+ +PI VR LVTAMRHAA+SREIAELAIRFRDKGVVGFDIA Sbjct 121 EIVEAVLAGFADGEKACAAENRPIVVRLLVTAMRHAAVSREIAELAIRFRDKGVVGFDIA 180 Query 181 GAEAGHPPTRHLDAFEYMRDHNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDI 240 GAEAG+PPTRHL+AF+YMRDHNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDI Sbjct 181 GAEAGNPPTRHLEAFDYMRDHNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDI 240 Query 241 DVDADGGFQLGRLAAILRDKRIPLELCPSSNVQTGAVASIAEHPFDLLARARFRVTVNTD 300 +V DG +LG+ A+ILRDKRIPLELCPSSNVQTGAV SIAEHPFDLLARARFRVTVNTD Sbjct 241 EVSDDGRVRLGQQASILRDKRIPLELCPSSNVQTGAVKSIAEHPFDLLARARFRVTVNTD 300 Query 301 NRLMSDTSMSLEMHRLVEAFGYGWSDLARFTVNAMKSAFIPFDQRLAIIDEVIKPRFAAL 360 NRLMSDT MS EMHRLVEAFGYGWSDL RFT+NAMKSAFIPFD+RLAIIDEVIKPR+A L Sbjct 301 NRLMSDTFMSREMHRLVEAFGYGWSDLERFTINAMKSAFIPFDERLAIIDEVIKPRYAVL 360 Query 361 MG 362 +G Sbjct 361 IG 362 >gi|336459596|gb|EGO38531.1| adenosine deaminase [Mycobacterium avium subsp. paratuberculosis S397] Length=366 Score = 633 bits (1633), Expect = 1e-179, Method: Compositional matrix adjust. Identities = 310/366 (85%), Positives = 336/366 (92%), Gaps = 4/366 (1%) Query 1 MTAAPTLQTIRLAPKALLHDHLDGGLRPATVLDIAGQVGYDDLPATDVDALASWFRTQSH 60 MTA L+ IR APKALLHDHLDGGLRP+TVLDIAGQ GYD LPATDV+ LA+WFRT+SH Sbjct 1 MTAPLELEQIRKAPKALLHDHLDGGLRPSTVLDIAGQTGYDGLPATDVEELATWFRTRSH 60 Query 61 SGSLERYLEPFSHTVAVMQTPEALYRVAFECAQDLAADSVVYAEVRFAPELHISCGLSFD 120 SGSLERYLEPFSHTVAVMQTPEAL+RVA+EC +DLA DSVVYAE+RFAPELHI+ G+SFD Sbjct 61 SGSLERYLEPFSHTVAVMQTPEALHRVAYECVEDLAEDSVVYAEIRFAPELHINRGMSFD 120 Query 121 DVVDTVLTGFAAGEKACAADGQPITVRCLVTAMRHAAMSREIAELAIRFRDKGVVGFDIA 180 ++VDTVL GFA GEKACAA G+PI VR LVTAMRHAA+SREIAELAIR+RDKGVVGFDIA Sbjct 121 EIVDTVLAGFADGEKACAAAGRPIVVRLLVTAMRHAAVSREIAELAIRWRDKGVVGFDIA 180 Query 181 GAEAGHPPTRHLDAFEYMRDHNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDI 240 GAEAG+PPTRHL+AF+YMRDHNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDI Sbjct 181 GAEAGNPPTRHLEAFDYMRDHNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDI 240 Query 241 DVDAD----GGFQLGRLAAILRDKRIPLELCPSSNVQTGAVASIAEHPFDLLARARFRVT 296 DV AD G +LGRLA ILRDKRIPLELCPSSNVQTGAV SIA+HPFDLLAR RFRVT Sbjct 241 DVLADGPDKGKVRLGRLANILRDKRIPLELCPSSNVQTGAVKSIADHPFDLLARTRFRVT 300 Query 297 VNTDNRLMSDTSMSLEMHRLVEAFGYGWSDLARFTVNAMKSAFIPFDQRLAIIDEVIKPR 356 VNTDNRLMSDT MS EMHRLV+AFGYGWSDL RFT+NAMKSAFIPFD+RLAIIDEVIKPR Sbjct 301 VNTDNRLMSDTYMSREMHRLVQAFGYGWSDLERFTINAMKSAFIPFDERLAIIDEVIKPR 360 Query 357 FAALMG 362 +A L+G Sbjct 361 YAVLIG 366 >gi|41409536|ref|NP_962372.1| adenosine deaminase [Mycobacterium avium subsp. paratuberculosis K-10] gi|118466331|ref|YP_883432.1| adenosine deaminase [Mycobacterium avium 104] gi|254776727|ref|ZP_05218243.1| adenosine deaminase [Mycobacterium avium subsp. avium ATCC 25291] gi|81570933|sp|Q73UD0.1|ADD_MYCPA RecName: Full=Adenosine deaminase; AltName: Full=Adenosine aminohydrolase gi|166198304|sp|A0QKJ4.1|ADD_MYCA1 RecName: Full=Adenosine deaminase; AltName: Full=Adenosine aminohydrolase gi|41398367|gb|AAS05988.1| Add [Mycobacterium avium subsp. paratuberculosis K-10] gi|118167618|gb|ABK68515.1| adenosine deaminase [Mycobacterium avium 104] Length=366 Score = 632 bits (1629), Expect = 4e-179, Method: Compositional matrix adjust. Identities = 309/366 (85%), Positives = 335/366 (92%), Gaps = 4/366 (1%) Query 1 MTAAPTLQTIRLAPKALLHDHLDGGLRPATVLDIAGQVGYDDLPATDVDALASWFRTQSH 60 MTA L+ IR APKALLHDHLDGGLRP+TVLDIAGQ GYD LPATDV+ LA+WFRT+SH Sbjct 1 MTAPLELEQIRKAPKALLHDHLDGGLRPSTVLDIAGQTGYDGLPATDVEELATWFRTRSH 60 Query 61 SGSLERYLEPFSHTVAVMQTPEALYRVAFECAQDLAADSVVYAEVRFAPELHISCGLSFD 120 SGSLERYLEPFSHTVAVMQTPEAL+RVA+EC +DLA DSVVYAE+RFAPELHI+ G+SFD Sbjct 61 SGSLERYLEPFSHTVAVMQTPEALHRVAYECVEDLAEDSVVYAEIRFAPELHINRGMSFD 120 Query 121 DVVDTVLTGFAAGEKACAADGQPITVRCLVTAMRHAAMSREIAELAIRFRDKGVVGFDIA 180 ++VD VL GFA GEKACAA G+PI VR LVTAMRHAA+SREIAELAIR+RDKGVVGFDIA Sbjct 121 EIVDAVLAGFADGEKACAAAGRPIVVRLLVTAMRHAAVSREIAELAIRWRDKGVVGFDIA 180 Query 181 GAEAGHPPTRHLDAFEYMRDHNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDI 240 GAEAG+PPTRHL+AF+YMRDHNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDI Sbjct 181 GAEAGNPPTRHLEAFDYMRDHNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDI 240 Query 241 DVDAD----GGFQLGRLAAILRDKRIPLELCPSSNVQTGAVASIAEHPFDLLARARFRVT 296 DV AD G +LGRLA ILRDKRIPLELCPSSNVQTGAV SIA+HPFDLLAR RFRVT Sbjct 241 DVLADGPDKGKVRLGRLANILRDKRIPLELCPSSNVQTGAVKSIADHPFDLLARTRFRVT 300 Query 297 VNTDNRLMSDTSMSLEMHRLVEAFGYGWSDLARFTVNAMKSAFIPFDQRLAIIDEVIKPR 356 VNTDNRLMSDT MS EMHRLV+AFGYGWSDL RFT+NAMKSAFIPFD+RLAIIDEVIKPR Sbjct 301 VNTDNRLMSDTYMSREMHRLVQAFGYGWSDLERFTINAMKSAFIPFDERLAIIDEVIKPR 360 Query 357 FAALMG 362 +A L+G Sbjct 361 YAVLIG 366 >gi|296168864|ref|ZP_06850536.1| adenosine deaminase [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295896481|gb|EFG76131.1| adenosine deaminase [Mycobacterium parascrofulaceum ATCC BAA-614] Length=362 Score = 625 bits (1613), Expect = 2e-177, Method: Compositional matrix adjust. Identities = 303/355 (86%), Positives = 329/355 (93%), Gaps = 0/355 (0%) Query 7 LQTIRLAPKALLHDHLDGGLRPATVLDIAGQVGYDDLPATDVDALASWFRTQSHSGSLER 66 L+ I+ APKALLHDHLDGGLRP+TV+DIAGQ GYD LP TDVD LA+WFRT+SHSGSLER Sbjct 6 LEQIKKAPKALLHDHLDGGLRPSTVVDIAGQTGYDGLPTTDVDELATWFRTRSHSGSLER 65 Query 67 YLEPFSHTVAVMQTPEALYRVAFECAQDLAADSVVYAEVRFAPELHISCGLSFDDVVDTV 126 YLEPFSHTVAVMQTP+AL+RVA+EC +DLAADSVVYAE+RFAPELHI GLSFD +VD V Sbjct 66 YLEPFSHTVAVMQTPDALHRVAYECVEDLAADSVVYAEIRFAPELHIDRGLSFDAIVDAV 125 Query 127 LTGFAAGEKACAADGQPITVRCLVTAMRHAAMSREIAELAIRFRDKGVVGFDIAGAEAGH 186 L G A GEKACAA G+PI VR LVTAMRHAA+SREIAELAIRFRDKGVVGFDIAGAEAG+ Sbjct 126 LAGLADGEKACAAAGRPIVVRLLVTAMRHAAVSREIAELAIRFRDKGVVGFDIAGAEAGN 185 Query 187 PPTRHLDAFEYMRDHNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDIDVDADG 246 PPTRHLDAFEYMRDHNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDIDV +G Sbjct 186 PPTRHLDAFEYMRDHNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDIDVLGNG 245 Query 247 GFQLGRLAAILRDKRIPLELCPSSNVQTGAVASIAEHPFDLLARARFRVTVNTDNRLMSD 306 +LGRLA+ILRDKRIPLELCPSSNVQTGAV SIA+HPFDLLAR RFRVTVNTDNRLMSD Sbjct 246 EVRLGRLASILRDKRIPLELCPSSNVQTGAVKSIADHPFDLLARTRFRVTVNTDNRLMSD 305 Query 307 TSMSLEMHRLVEAFGYGWSDLARFTVNAMKSAFIPFDQRLAIIDEVIKPRFAALM 361 T+MSLEM RLVEAFGYGWSDL RFT+NAMKSAF+PFD+RLAIID+VIKPR+A L+ Sbjct 306 TTMSLEMCRLVEAFGYGWSDLERFTINAMKSAFLPFDERLAIIDDVIKPRYAVLI 360 >gi|333991780|ref|YP_004524394.1| adenosine deaminase Add [Mycobacterium sp. JDM601] gi|333487748|gb|AEF37140.1| adenosine deaminase Add [Mycobacterium sp. JDM601] Length=365 Score = 619 bits (1596), Expect = 2e-175, Method: Compositional matrix adjust. Identities = 307/365 (85%), Positives = 327/365 (90%), Gaps = 3/365 (0%) Query 1 MTAAPTLQTIRLAPKALLHDHLDGGLRPATVLDIAGQVGYDDLPATDVDALASWFRTQSH 60 MT TL+TIR APKALLHDHLDGGLRPATV+DIAGQVGYD LPATD + LA+WFRT+SH Sbjct 1 MTTPLTLETIRQAPKALLHDHLDGGLRPATVVDIAGQVGYDGLPATDPEELATWFRTRSH 60 Query 61 SGSLERYLEPFSHTVAVMQTPEALYRVAFECAQDLAADSVVYAEVRFAPELHISCGLSFD 120 SGSLERYLEPFSHTVAVMQTP+AL+RVA EC +DLAAD+VVYAEVRFAPELHI GLSFD Sbjct 61 SGSLERYLEPFSHTVAVMQTPDALFRVAAECVEDLAADAVVYAEVRFAPELHIEGGLSFD 120 Query 121 DVVDTVLTGFAAGEKACAADGQPITVRCLVTAMRHAAMSREIAELAIRFRDKGVVGFDIA 180 V D VL GFA GE+ AA G+ ITVRCLVTAMRHAA+SREIAELAIRFRDKGVVGFDIA Sbjct 121 AVTDAVLAGFADGERRAAAAGRDITVRCLVTAMRHAALSREIAELAIRFRDKGVVGFDIA 180 Query 181 GAEAGHPPTRHLDAFEYMRDHNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDI 240 GAEAGHPP+RHLDAFEYMRDHNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRI DDI Sbjct 181 GAEAGHPPSRHLDAFEYMRDHNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRITDDI 240 Query 241 DV---DADGGFQLGRLAAILRDKRIPLELCPSSNVQTGAVASIAEHPFDLLARARFRVTV 297 V D DG +LGRLAAILRDKRIPLELCPSSNVQTGAV SIAEHPFDLLARAR RVT+ Sbjct 241 TVDPEDPDGPVRLGRLAAILRDKRIPLELCPSSNVQTGAVGSIAEHPFDLLARARLRVTI 300 Query 298 NTDNRLMSDTSMSLEMHRLVEAFGYGWSDLARFTVNAMKSAFIPFDQRLAIIDEVIKPRF 357 NTDNRLMSDT+MS EM L E FGYGW+DL RF VNAMKSAFIPFDQR+AII+EVIKPRF Sbjct 301 NTDNRLMSDTTMSKEMAVLAETFGYGWTDLQRFMVNAMKSAFIPFDQRVAIIEEVIKPRF 360 Query 358 AALMG 362 A L+G Sbjct 361 AVLVG 365 >gi|118467725|ref|YP_886052.1| adenosine deaminase [Mycobacterium smegmatis str. MC2 155] gi|118169012|gb|ABK69908.1| adenosine deaminase [Mycobacterium smegmatis str. MC2 155] Length=366 Score = 619 bits (1596), Expect = 2e-175, Method: Compositional matrix adjust. Identities = 303/362 (84%), Positives = 326/362 (91%), Gaps = 0/362 (0%) Query 1 MTAAPTLQTIRLAPKALLHDHLDGGLRPATVLDIAGQVGYDDLPATDVDALASWFRTQSH 60 M+ +L+ I APKALLHDHLDGGLRPATVLD+AGQVGYD+LPATD D LA++FRT +H Sbjct 5 MSTPLSLEKITNAPKALLHDHLDGGLRPATVLDLAGQVGYDNLPATDADELATFFRTAAH 64 Query 61 SGSLERYLEPFSHTVAVMQTPEALYRVAFECAQDLAADSVVYAEVRFAPELHISCGLSFD 120 SGSL RYLEPF+HTV VMQTPEAL+RVAFEC +DLAAD+VVYAEVRFAPELHI GLS D Sbjct 65 SGSLVRYLEPFAHTVGVMQTPEALHRVAFECVEDLAADNVVYAEVRFAPELHIDGGLSLD 124 Query 121 DVVDTVLTGFAAGEKACAADGQPITVRCLVTAMRHAAMSREIAELAIRFRDKGVVGFDIA 180 DVVD VL GFA GEKA AA G+ I VRCLVTAMRHAA SREIAELAIRFRDKGVVGFDIA Sbjct 125 DVVDAVLAGFADGEKASAAAGRTIVVRCLVTAMRHAARSREIAELAIRFRDKGVVGFDIA 184 Query 181 GAEAGHPPTRHLDAFEYMRDHNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDI 240 GAEAG+PP+RHLDAFEYMR +NARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDI Sbjct 185 GAEAGYPPSRHLDAFEYMRSNNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDI 244 Query 241 DVDADGGFQLGRLAAILRDKRIPLELCPSSNVQTGAVASIAEHPFDLLARARFRVTVNTD 300 DG QLGRLA++LRDKRIPLE+CPSSNVQTGAV SIAEHPFD LAR RFRVTVNTD Sbjct 245 SETPDGTQQLGRLASLLRDKRIPLEMCPSSNVQTGAVKSIAEHPFDRLARLRFRVTVNTD 304 Query 301 NRLMSDTSMSLEMHRLVEAFGYGWSDLARFTVNAMKSAFIPFDQRLAIIDEVIKPRFAAL 360 NRLMSDT+MS EMHRLVEAFGYGWSDL RFT+NAMKSAFIPFDQRLAIIDEVIKPR+A L Sbjct 305 NRLMSDTTMSQEMHRLVEAFGYGWSDLERFTINAMKSAFIPFDQRLAIIDEVIKPRYAVL 364 Query 361 MG 362 +G Sbjct 365 VG 366 >gi|108798204|ref|YP_638401.1| adenosine deaminase [Mycobacterium sp. MCS] gi|119867300|ref|YP_937252.1| adenosine deaminase [Mycobacterium sp. KMS] gi|123070526|sp|Q1BCN9.1|ADD_MYCSS RecName: Full=Adenosine deaminase; AltName: Full=Adenosine aminohydrolase gi|166198307|sp|A1UCA4.1|ADD_MYCSK RecName: Full=Adenosine deaminase; AltName: Full=Adenosine aminohydrolase gi|108768623|gb|ABG07345.1| adenosine deaminase [Mycobacterium sp. MCS] gi|119693389|gb|ABL90462.1| adenosine deaminase [Mycobacterium sp. KMS] Length=362 Score = 609 bits (1571), Expect = 2e-172, Method: Compositional matrix adjust. Identities = 300/362 (83%), Positives = 324/362 (90%), Gaps = 0/362 (0%) Query 1 MTAAPTLQTIRLAPKALLHDHLDGGLRPATVLDIAGQVGYDDLPATDVDALASWFRTQSH 60 MT TL+ I APKALLHDHLDGGLRP+TVL++AGQ GYDDLPA DVD LA++FRT +H Sbjct 1 MTTPLTLENISQAPKALLHDHLDGGLRPSTVLELAGQYGYDDLPADDVDELATFFRTAAH 60 Query 61 SGSLERYLEPFSHTVAVMQTPEALYRVAFECAQDLAADSVVYAEVRFAPELHISCGLSFD 120 SGSL RYLEPF+HTV VMQT EAL+RVAFEC +DLA D+VVYAEVRFAPELHI G+ D Sbjct 61 SGSLVRYLEPFAHTVGVMQTAEALHRVAFECVEDLAGDNVVYAEVRFAPELHIEGGMGLD 120 Query 121 DVVDTVLTGFAAGEKACAADGQPITVRCLVTAMRHAAMSREIAELAIRFRDKGVVGFDIA 180 VVD VL GFA GEKA A+ G+ ITVRCLVTAMRHAA SREIAELAIRFRD+GVVGFDIA Sbjct 121 AVVDAVLAGFADGEKAAASAGRTITVRCLVTAMRHAARSREIAELAIRFRDRGVVGFDIA 180 Query 181 GAEAGHPPTRHLDAFEYMRDHNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDI 240 GAEAG+PPTRHLDAFEYMR +NARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDI Sbjct 181 GAEAGYPPTRHLDAFEYMRGNNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDI 240 Query 241 DVDADGGFQLGRLAAILRDKRIPLELCPSSNVQTGAVASIAEHPFDLLARARFRVTVNTD 300 V DG +LGRLAAILRDKRIPLELCPSSNVQTGAVASIAEHPFDLLAR RFRVTVNTD Sbjct 241 TVAPDGQVKLGRLAAILRDKRIPLELCPSSNVQTGAVASIAEHPFDLLARTRFRVTVNTD 300 Query 301 NRLMSDTSMSLEMHRLVEAFGYGWSDLARFTVNAMKSAFIPFDQRLAIIDEVIKPRFAAL 360 NRLMSDTSMS EM RLVEAFGYGWSDLARFT+NAMKS+FIPFD+RLA+ID+VIKPR+A L Sbjct 301 NRLMSDTSMSQEMLRLVEAFGYGWSDLARFTINAMKSSFIPFDERLALIDDVIKPRYAVL 360 Query 361 MG 362 G Sbjct 361 AG 362 >gi|126433861|ref|YP_001069552.1| adenosine deaminase [Mycobacterium sp. JLS] gi|166198306|sp|A3PVY4.1|ADD_MYCSJ RecName: Full=Adenosine deaminase; AltName: Full=Adenosine aminohydrolase gi|126233661|gb|ABN97061.1| adenosine deaminase [Mycobacterium sp. JLS] Length=362 Score = 608 bits (1568), Expect = 4e-172, Method: Compositional matrix adjust. Identities = 299/362 (83%), Positives = 324/362 (90%), Gaps = 0/362 (0%) Query 1 MTAAPTLQTIRLAPKALLHDHLDGGLRPATVLDIAGQVGYDDLPATDVDALASWFRTQSH 60 MT TL+ I APKALLHDHLDGGLRP+TVL++AGQ GYDDLPA DVD LA++FRT +H Sbjct 1 MTTPLTLENISQAPKALLHDHLDGGLRPSTVLELAGQYGYDDLPADDVDELATFFRTAAH 60 Query 61 SGSLERYLEPFSHTVAVMQTPEALYRVAFECAQDLAADSVVYAEVRFAPELHISCGLSFD 120 SGSL RYLEPF+HTV VMQT EAL+RVAFEC +DLA D+VVYAEVRFAPELHI G+ D Sbjct 61 SGSLVRYLEPFAHTVGVMQTAEALHRVAFECVEDLAGDNVVYAEVRFAPELHIEGGMGLD 120 Query 121 DVVDTVLTGFAAGEKACAADGQPITVRCLVTAMRHAAMSREIAELAIRFRDKGVVGFDIA 180 VVD VL GFA GEKA A+ G+ ITVRCLVTAMRHAA SREIAELAIRFRD+GVVGFDIA Sbjct 121 AVVDAVLAGFADGEKAAASAGRTITVRCLVTAMRHAARSREIAELAIRFRDRGVVGFDIA 180 Query 181 GAEAGHPPTRHLDAFEYMRDHNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDI 240 GAEAG+PPTRHLDAFEYMR +NARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDI Sbjct 181 GAEAGYPPTRHLDAFEYMRGNNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDI 240 Query 241 DVDADGGFQLGRLAAILRDKRIPLELCPSSNVQTGAVASIAEHPFDLLARARFRVTVNTD 300 V DG +LGRLAAILRDKRIPLELCPSSNVQTGAVASIAEHPFDLLAR RFRVTVNTD Sbjct 241 TVAPDGQVKLGRLAAILRDKRIPLELCPSSNVQTGAVASIAEHPFDLLARTRFRVTVNTD 300 Query 301 NRLMSDTSMSLEMHRLVEAFGYGWSDLARFTVNAMKSAFIPFDQRLAIIDEVIKPRFAAL 360 NRLMSDT+MS EM RLVEAFGYGWSDLARFT+NAMKS+FIPFD+RLA+ID+VIKPR+A L Sbjct 301 NRLMSDTTMSQEMLRLVEAFGYGWSDLARFTINAMKSSFIPFDERLALIDDVIKPRYAVL 360 Query 361 MG 362 G Sbjct 361 AG 362 >gi|120402598|ref|YP_952427.1| adenosine deaminase [Mycobacterium vanbaalenii PYR-1] gi|166198310|sp|A1T5H1.1|ADD_MYCVP RecName: Full=Adenosine deaminase; AltName: Full=Adenosine aminohydrolase gi|119955416|gb|ABM12421.1| adenosine deaminase [Mycobacterium vanbaalenii PYR-1] Length=362 Score = 607 bits (1565), Expect = 1e-171, Method: Compositional matrix adjust. Identities = 297/362 (83%), Positives = 324/362 (90%), Gaps = 0/362 (0%) Query 1 MTAAPTLQTIRLAPKALLHDHLDGGLRPATVLDIAGQVGYDDLPATDVDALASWFRTQSH 60 MT T IR APKALLHDHLDGGLRP+TVL++A Q GY+DLPA D D LA++FRT +H Sbjct 1 MTTPLTFDNIRRAPKALLHDHLDGGLRPSTVLELAEQYGYEDLPAHDADGLATFFRTAAH 60 Query 61 SGSLERYLEPFSHTVAVMQTPEALYRVAFECAQDLAADSVVYAEVRFAPELHISCGLSFD 120 SGSL RYLEPF+HTV VMQ P+AL+RVA EC +DLAAD+VVYAEVRFAPELHI GLS D Sbjct 61 SGSLVRYLEPFAHTVGVMQNPDALHRVARECVEDLAADNVVYAEVRFAPELHIDGGLSLD 120 Query 121 DVVDTVLTGFAAGEKACAADGQPITVRCLVTAMRHAAMSREIAELAIRFRDKGVVGFDIA 180 VVD VL GFA GEKA AADG+ ITVRCLVTAMRHAA SREIAELAIRFRDKGVVGFDIA Sbjct 121 AVVDAVLAGFADGEKAAAADGRAITVRCLVTAMRHAARSREIAELAIRFRDKGVVGFDIA 180 Query 181 GAEAGHPPTRHLDAFEYMRDHNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDI 240 GAEAG+PP+RHLDAFEYMR +NARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDI Sbjct 181 GAEAGYPPSRHLDAFEYMRSNNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDI 240 Query 241 DVDADGGFQLGRLAAILRDKRIPLELCPSSNVQTGAVASIAEHPFDLLARARFRVTVNTD 300 ++DADG +LGRLA++LRDKRIP E+CPSSNVQTGAVASIAEHPFD LAR RFRVTVNTD Sbjct 241 EIDADGNAKLGRLASLLRDKRIPFEMCPSSNVQTGAVASIAEHPFDRLARLRFRVTVNTD 300 Query 301 NRLMSDTSMSLEMHRLVEAFGYGWSDLARFTVNAMKSAFIPFDQRLAIIDEVIKPRFAAL 360 NRLMSDTSMS+EM RLVEAFGYGWSDL RFT+NAMKSAFI FD+RLAIIDEVIKPR+A L Sbjct 301 NRLMSDTSMSMEMLRLVEAFGYGWSDLERFTINAMKSAFIAFDERLAIIDEVIKPRYAVL 360 Query 361 MG 362 +G Sbjct 361 VG 362 >gi|467172|gb|AAA17330.1| add [Mycobacterium leprae] Length=332 Score = 601 bits (1550), Expect = 5e-170, Method: Compositional matrix adjust. Identities = 293/332 (89%), Positives = 311/332 (94%), Gaps = 0/332 (0%) Query 31 VLDIAGQVGYDDLPATDVDALASWFRTQSHSGSLERYLEPFSHTVAVMQTPEALYRVAFE 90 +LDIAGQVGYD LPATDV++L +WFRT SHSGSLERYLEPFSHTVAVMQTPEAL+RVA+E Sbjct 1 MLDIAGQVGYDRLPATDVESLETWFRTASHSGSLERYLEPFSHTVAVMQTPEALHRVAYE 60 Query 91 CAQDLAADSVVYAEVRFAPELHISCGLSFDDVVDTVLTGFAAGEKACAADGQPITVRCLV 150 C +DLAADSVVYAEVRFAPELHI GLSFD+V+ +VL GFA GE+ACAA+G ITVRCLV Sbjct 61 CVEDLAADSVVYAEVRFAPELHIDEGLSFDEVLASVLAGFADGERACAAEGNAITVRCLV 120 Query 151 TAMRHAAMSREIAELAIRFRDKGVVGFDIAGAEAGHPPTRHLDAFEYMRDHNARFTIHAG 210 TAMRHAAMSREIAELAIRFRDKGVVGFDIAGAEAGHPPTRHLDAFEYMR +NARFTIHAG Sbjct 121 TAMRHAAMSREIAELAIRFRDKGVVGFDIAGAEAGHPPTRHLDAFEYMRSNNARFTIHAG 180 Query 211 EAFGLPSIHEAIAFCGADRLGHGVRIVDDIDVDADGGFQLGRLAAILRDKRIPLELCPSS 270 EAFGLPSIHEAIAFCGADRLGHGVRIVDDIDVD GG +LG LA+ILRDKRIPLELCPSS Sbjct 181 EAFGLPSIHEAIAFCGADRLGHGVRIVDDIDVDPGGGIRLGPLASILRDKRIPLELCPSS 240 Query 271 NVQTGAVASIAEHPFDLLARARFRVTVNTDNRLMSDTSMSLEMHRLVEAFGYGWSDLARF 330 N+QTGAVASI EHPFDLLA ARFRVTVNTDNRLMSDTSMSLEMHRLVEAFGYGW DL RF Sbjct 241 NLQTGAVASITEHPFDLLAWARFRVTVNTDNRLMSDTSMSLEMHRLVEAFGYGWGDLERF 300 Query 331 TVNAMKSAFIPFDQRLAIIDEVIKPRFAALMG 362 T+NAMKSAFIPFDQRLAIIDEVIKPRFA L+G Sbjct 301 TINAMKSAFIPFDQRLAIIDEVIKPRFAVLVG 332 >gi|145225419|ref|YP_001136097.1| adenosine deaminase [Mycobacterium gilvum PYR-GCK] gi|315445767|ref|YP_004078646.1| adenosine deaminase [Mycobacterium sp. Spyr1] gi|189027487|sp|A4TEW1.1|ADD_MYCGI RecName: Full=Adenosine deaminase; AltName: Full=Adenosine aminohydrolase gi|145217905|gb|ABP47309.1| adenosine deaminase [Mycobacterium gilvum PYR-GCK] gi|315264070|gb|ADU00812.1| adenosine deaminase [Mycobacterium sp. Spyr1] Length=362 Score = 587 bits (1514), Expect = 7e-166, Method: Compositional matrix adjust. Identities = 293/362 (81%), Positives = 321/362 (89%), Gaps = 0/362 (0%) Query 1 MTAAPTLQTIRLAPKALLHDHLDGGLRPATVLDIAGQVGYDDLPATDVDALASWFRTQSH 60 MT TL+ IR APKALLHDHLDGGLRP+TVL++A Q GYDDLPA D D LA +FRT +H Sbjct 1 MTTPLTLENIRRAPKALLHDHLDGGLRPSTVLELAEQYGYDDLPAHDADELAEFFRTAAH 60 Query 61 SGSLERYLEPFSHTVAVMQTPEALYRVAFECAQDLAADSVVYAEVRFAPELHISCGLSFD 120 SGSL RYLEPF+HTV VMQ +AL+RVA EC +DLA D+VVYAE+RFAPELHI GLS D Sbjct 61 SGSLVRYLEPFAHTVGVMQNHDALHRVARECVEDLADDNVVYAEIRFAPELHIDGGLSLD 120 Query 121 DVVDTVLTGFAAGEKACAADGQPITVRCLVTAMRHAAMSREIAELAIRFRDKGVVGFDIA 180 VV+ VL GFA GEKA AA G+ ITVRCLVTAMRHAA SREIA LAIRFRD+GVVGFDIA Sbjct 121 AVVEAVLAGFADGEKAAAAAGRTITVRCLVTAMRHAARSREIAALAIRFRDQGVVGFDIA 180 Query 181 GAEAGHPPTRHLDAFEYMRDHNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDI 240 GAEAG+PP+RHLDAFEYMR +NARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDI Sbjct 181 GAEAGYPPSRHLDAFEYMRSNNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDI 240 Query 241 DVDADGGFQLGRLAAILRDKRIPLELCPSSNVQTGAVASIAEHPFDLLARARFRVTVNTD 300 D+DA+GG +LGRLAA+LRDKRIP E+CPSSNVQTGAVASIAEHPFD LAR RFRVTVNTD Sbjct 241 DMDAEGGPKLGRLAALLRDKRIPFEMCPSSNVQTGAVASIAEHPFDRLARLRFRVTVNTD 300 Query 301 NRLMSDTSMSLEMHRLVEAFGYGWSDLARFTVNAMKSAFIPFDQRLAIIDEVIKPRFAAL 360 NRLMSDT+MSLEM RLVEAFGYGWSDL RFT+NAMKSAFI F +RLAIIDEVIKPR+A L Sbjct 301 NRLMSDTTMSLEMLRLVEAFGYGWSDLERFTINAMKSAFISFPERLAIIDEVIKPRYAVL 360 Query 361 MG 362 +G Sbjct 361 VG 362 >gi|169630749|ref|YP_001704398.1| adenosine deaminase [Mycobacterium abscessus ATCC 19977] gi|226710978|sp|B1MFZ9.1|ADD_MYCA9 RecName: Full=Adenosine deaminase; AltName: Full=Adenosine aminohydrolase gi|169242716|emb|CAM63744.1| Adenosine deaminase [Mycobacterium abscessus] Length=362 Score = 572 bits (1474), Expect = 3e-161, Method: Compositional matrix adjust. Identities = 278/362 (77%), Positives = 312/362 (87%), Gaps = 0/362 (0%) Query 1 MTAAPTLQTIRLAPKALLHDHLDGGLRPATVLDIAGQVGYDDLPATDVDALASWFRTQSH 60 MTA L +I APKALLHDHLDGGLRP TVLD+A + GY++LPA D ALASWFRT + Sbjct 1 MTAELDLVSITQAPKALLHDHLDGGLRPGTVLDLARETGYENLPAQDETALASWFRTAAD 60 Query 61 SGSLERYLEPFSHTVAVMQTPEALYRVAFECAQDLAADSVVYAEVRFAPELHISCGLSFD 120 SGSLE+YLE F+HTV VMQT AL+RVA EC +DLAAD VVYAEVRFAPELHI GL+ D Sbjct 61 SGSLEQYLETFAHTVGVMQTASALHRVAAECVEDLAADGVVYAEVRFAPELHIDAGLTLD 120 Query 121 DVVDTVLTGFAAGEKACAADGQPITVRCLVTAMRHAAMSREIAELAIRFRDKGVVGFDIA 180 DV+D VL GFA GE+ +A G+ I VR LVTAMRHAA SREIAELA++FRD+G VGFDIA Sbjct 121 DVMDAVLAGFADGERQASAAGKRIKVRTLVTAMRHAARSREIAELAVKFRDRGAVGFDIA 180 Query 181 GAEAGHPPTRHLDAFEYMRDHNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDI 240 GAEAG+PPTRHLDAFEYMR+ N+RFTIHAGE FGLPSIHEAIAFCGADRLGHGVRIVDDI Sbjct 181 GAEAGYPPTRHLDAFEYMRNANSRFTIHAGEGFGLPSIHEAIAFCGADRLGHGVRIVDDI 240 Query 241 DVDADGGFQLGRLAAILRDKRIPLELCPSSNVQTGAVASIAEHPFDLLARARFRVTVNTD 300 D+ DG LGRL+++LRDKR+PLELCPSSNVQTGAV S+A+HPFDLLAR RFRVTVNTD Sbjct 241 DIGPDGTAHLGRLSSLLRDKRVPLELCPSSNVQTGAVESLADHPFDLLARLRFRVTVNTD 300 Query 301 NRLMSDTSMSLEMHRLVEAFGYGWSDLARFTVNAMKSAFIPFDQRLAIIDEVIKPRFAAL 360 NRLMSDT+MS EM RLVE FGYGWSDL RFT+NAMKSAFIPFD+RLAIID+VIKP +A L Sbjct 301 NRLMSDTTMSREMLRLVETFGYGWSDLQRFTINAMKSAFIPFDERLAIIDDVIKPGYAVL 360 Query 361 MG 362 +G Sbjct 361 IG 362 >gi|226305535|ref|YP_002765495.1| adenosine deaminase [Rhodococcus erythropolis PR4] gi|226184652|dbj|BAH32756.1| adenosine deaminase [Rhodococcus erythropolis PR4] Length=361 Score = 556 bits (1433), Expect = 2e-156, Method: Compositional matrix adjust. Identities = 273/359 (77%), Positives = 304/359 (85%), Gaps = 0/359 (0%) Query 4 APTLQTIRLAPKALLHDHLDGGLRPATVLDIAGQVGYDDLPATDVDALASWFRTQSHSGS 63 AP L TIR APK LLHDHLDGGLRP TVL++A Q GYD+LPAT LA WFRT + SGS Sbjct 3 APELTTIRSAPKVLLHDHLDGGLRPETVLELAEQCGYDELPATTASELAQWFRTAADSGS 62 Query 64 LERYLEPFSHTVAVMQTPEALYRVAFECAQDLAADSVVYAEVRFAPELHISCGLSFDDVV 123 LE YLE F+HTVAVMQTPE L RVA ECA+DLA D+VVYAE+RFAPE H+ GLS D+VV Sbjct 63 LELYLETFAHTVAVMQTPEGLARVARECAEDLADDNVVYAEIRFAPEQHLEQGLSLDEVV 122 Query 124 DTVLTGFAAGEKACAADGQPITVRCLVTAMRHAAMSREIAELAIRFRDKGVVGFDIAGAE 183 + VL GF AGE A G+ I + CL+TAMRHAA SREIAELA+RFRD+GVVGFDIAGAE Sbjct 123 EHVLEGFRAGESAARVAGREIRIGCLLTAMRHAARSREIAELAVRFRDRGVVGFDIAGAE 182 Query 184 AGHPPTRHLDAFEYMRDHNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDIDVD 243 AG+PP+RHLDAFEYMRD NA FTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDIDV Sbjct 183 AGNPPSRHLDAFEYMRDANAHFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDIDVA 242 Query 244 ADGGFQLGRLAAILRDKRIPLELCPSSNVQTGAVASIAEHPFDLLARARFRVTVNTDNRL 303 GG +LGRLA +RD RIPLELCPSSNVQTGAVA++++HPF LLA RFRVTVNTDNRL Sbjct 243 GQGGAELGRLANYVRDMRIPLELCPSSNVQTGAVAALSDHPFGLLADLRFRVTVNTDNRL 302 Query 304 MSDTSMSLEMHRLVEAFGYGWSDLARFTVNAMKSAFIPFDQRLAIIDEVIKPRFAALMG 362 MSDTSMS EM LVE FGYGW+DL RFT+NAMKSAFIPFD+RLA+ID+VIKP +A L+G Sbjct 303 MSDTSMSREMAALVETFGYGWTDLERFTINAMKSAFIPFDERLALIDDVIKPGYAVLIG 361 >gi|229489626|ref|ZP_04383489.1| adenosine deaminase [Rhodococcus erythropolis SK121] gi|229323723|gb|EEN89481.1| adenosine deaminase [Rhodococcus erythropolis SK121] Length=361 Score = 554 bits (1427), Expect = 9e-156, Method: Compositional matrix adjust. Identities = 273/359 (77%), Positives = 303/359 (85%), Gaps = 0/359 (0%) Query 4 APTLQTIRLAPKALLHDHLDGGLRPATVLDIAGQVGYDDLPATDVDALASWFRTQSHSGS 63 AP L TIR APK LLHDHLDGGLRP TVL++A Q GYD+LPA LA WFRT + SGS Sbjct 3 APELTTIRSAPKVLLHDHLDGGLRPETVLELAEQCGYDELPANTASELAQWFRTAADSGS 62 Query 64 LERYLEPFSHTVAVMQTPEALYRVAFECAQDLAADSVVYAEVRFAPELHISCGLSFDDVV 123 LE YLE F+HTVAVMQTPE L RVA ECA+DLA D+VVYAEVRFAPE H+ GLS D+VV Sbjct 63 LELYLETFAHTVAVMQTPEGLARVARECAEDLADDNVVYAEVRFAPEQHLEQGLSLDEVV 122 Query 124 DTVLTGFAAGEKACAADGQPITVRCLVTAMRHAAMSREIAELAIRFRDKGVVGFDIAGAE 183 + VL GF AGE A G+ I + CL+TAMRHAA SREIAELA+RFRD+GVVGFDIAGAE Sbjct 123 EHVLEGFRAGESAARVAGREIRIGCLLTAMRHAARSREIAELAVRFRDRGVVGFDIAGAE 182 Query 184 AGHPPTRHLDAFEYMRDHNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDIDVD 243 AG+PP+RHLDAFEYMRD NA FTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDIDV Sbjct 183 AGNPPSRHLDAFEYMRDANAHFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDIDVG 242 Query 244 ADGGFQLGRLAAILRDKRIPLELCPSSNVQTGAVASIAEHPFDLLARARFRVTVNTDNRL 303 GG +LGRLA +RD RIPLELCPSSNVQTGAVA++A+HPF LLA RFRVTVNTDNRL Sbjct 243 VPGGAELGRLANYVRDMRIPLELCPSSNVQTGAVAALADHPFGLLADLRFRVTVNTDNRL 302 Query 304 MSDTSMSLEMHRLVEAFGYGWSDLARFTVNAMKSAFIPFDQRLAIIDEVIKPRFAALMG 362 MSDT+MS EM LVE FGYGW+DL RFT+NAMKSAFIPFD+RLA+ID+VIKP +A L+G Sbjct 303 MSDTTMSREMAALVETFGYGWTDLERFTINAMKSAFIPFDERLALIDDVIKPGYAVLIG 361 >gi|111023214|ref|YP_706186.1| adenosine deaminase [Rhodococcus jostii RHA1] gi|110822744|gb|ABG98028.1| adenosine deaminase [Rhodococcus jostii RHA1] Length=361 Score = 540 bits (1392), Expect = 1e-151, Method: Compositional matrix adjust. Identities = 267/356 (75%), Positives = 294/356 (83%), Gaps = 0/356 (0%) Query 7 LQTIRLAPKALLHDHLDGGLRPATVLDIAGQVGYDDLPATDVDALASWFRTQSHSGSLER 66 L +R APK LLHDHLDGGLRP TVL++A GYD LPA ALA+WFR + SGSLER Sbjct 6 LSALRRAPKVLLHDHLDGGLRPETVLELARDCGYDALPADTAPALATWFREAADSGSLER 65 Query 67 YLEPFSHTVAVMQTPEALYRVAFECAQDLAADSVVYAEVRFAPELHISCGLSFDDVVDTV 126 YLE F+HTVAVMQTP L RVA ECA+DLAAD VVYAEVRFAPE H+ GL+ D+VV+ V Sbjct 66 YLETFAHTVAVMQTPVGLERVARECAEDLAADGVVYAEVRFAPEQHLEEGLTLDEVVEQV 125 Query 127 LTGFAAGEKACAADGQPITVRCLVTAMRHAAMSREIAELAIRFRDKGVVGFDIAGAEAGH 186 L GF AGE A GQ I + L+TAMRHAA SREIAELAIRFRD+GVVGFDIAGAEAG+ Sbjct 126 LLGFEAGESAAEVRGQNIRIGVLLTAMRHAARSREIAELAIRFRDRGVVGFDIAGAEAGN 185 Query 187 PPTRHLDAFEYMRDHNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDIDVDADG 246 PP+RHLDAFEYMR NA FTIHAGEAFGLPSIHEAIAFCG DRLGHGVRI DDI + DG Sbjct 186 PPSRHLDAFEYMRGSNAHFTIHAGEAFGLPSIHEAIAFCGTDRLGHGVRITDDITIGDDG 245 Query 247 GFQLGRLAAILRDKRIPLELCPSSNVQTGAVASIAEHPFDLLARARFRVTVNTDNRLMSD 306 LG+LA +RDKRIPLELCPSSNVQTGAV ++ HPFDLLAR RFRVTVNTDNRLMSD Sbjct 246 VPVLGKLANYVRDKRIPLELCPSSNVQTGAVDALENHPFDLLARLRFRVTVNTDNRLMSD 305 Query 307 TSMSLEMHRLVEAFGYGWSDLARFTVNAMKSAFIPFDQRLAIIDEVIKPRFAALMG 362 TSMS+EM RLVE FGYGW+DL R+T+NAMKSAFIPFDQRL +IDEVIKP FA L+G Sbjct 306 TSMSMEMLRLVETFGYGWTDLERYTINAMKSAFIPFDQRLQLIDEVIKPGFAVLVG 361 >gi|226365719|ref|YP_002783502.1| adenosine deaminase [Rhodococcus opacus B4] gi|226244209|dbj|BAH54557.1| adenosine deaminase [Rhodococcus opacus B4] Length=361 Score = 538 bits (1387), Expect = 4e-151, Method: Compositional matrix adjust. Identities = 266/356 (75%), Positives = 293/356 (83%), Gaps = 0/356 (0%) Query 7 LQTIRLAPKALLHDHLDGGLRPATVLDIAGQVGYDDLPATDVDALASWFRTQSHSGSLER 66 L +R APK LLHDHLDGGLRP TVL++A GYD LPA ALA+WFR + SGSLER Sbjct 6 LSALRRAPKVLLHDHLDGGLRPETVLELARDCGYDALPADTAPALATWFREAADSGSLER 65 Query 67 YLEPFSHTVAVMQTPEALYRVAFECAQDLAADSVVYAEVRFAPELHISCGLSFDDVVDTV 126 YLE F+HTVAVMQTP L RVA ECA+DLA D VVYAEVRFAPE H+ GL+ D+VV+ V Sbjct 66 YLETFAHTVAVMQTPVGLERVARECAEDLADDGVVYAEVRFAPEQHLEEGLTLDEVVEQV 125 Query 127 LTGFAAGEKACAADGQPITVRCLVTAMRHAAMSREIAELAIRFRDKGVVGFDIAGAEAGH 186 L GF AGE A GQ I + L+TAMRHAA SREIAELA+RFRD+GVVGFDIAGAEAG+ Sbjct 126 LLGFEAGESAAEVRGQNIRIGVLLTAMRHAARSREIAELAVRFRDRGVVGFDIAGAEAGN 185 Query 187 PPTRHLDAFEYMRDHNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDIDVDADG 246 PP+RHLDAFEYMR NA FTIHAGEAFGLPSIHEAIAFCG DRLGHGVRI DDI + ADG Sbjct 186 PPSRHLDAFEYMRGSNAHFTIHAGEAFGLPSIHEAIAFCGTDRLGHGVRITDDITIGADG 245 Query 247 GFQLGRLAAILRDKRIPLELCPSSNVQTGAVASIAEHPFDLLARARFRVTVNTDNRLMSD 306 LG+LA +RDKRIPLELCPSSNVQTGAV ++ HPFDLLAR RFRVTVNTDNRLMSD Sbjct 246 VPVLGKLANYVRDKRIPLELCPSSNVQTGAVDALENHPFDLLARLRFRVTVNTDNRLMSD 305 Query 307 TSMSLEMHRLVEAFGYGWSDLARFTVNAMKSAFIPFDQRLAIIDEVIKPRFAALMG 362 TSMS EM RLVE FGYGW+DL R+T+NAMKSAFIPFDQRL +IDEVIKP FA L+G Sbjct 306 TSMSQEMLRLVETFGYGWTDLERYTINAMKSAFIPFDQRLQLIDEVIKPGFAVLVG 361 >gi|312140768|ref|YP_004008104.1| adenosine deaminase [Rhodococcus equi 103S] gi|311890107|emb|CBH49425.1| adenosine deaminase [Rhodococcus equi 103S] Length=362 Score = 537 bits (1383), Expect = 1e-150, Method: Compositional matrix adjust. Identities = 269/362 (75%), Positives = 295/362 (82%), Gaps = 0/362 (0%) Query 1 MTAAPTLQTIRLAPKALLHDHLDGGLRPATVLDIAGQVGYDDLPATDVDALASWFRTQSH 60 MTA L +R APK LLHDHLDGGLRP TV ++A + GY LPA D LA+WFR + Sbjct 1 MTAPLDLDYLRSAPKVLLHDHLDGGLRPGTVAELADECGYTGLPAETPDGLAAWFRNAAD 60 Query 61 SGSLERYLEPFSHTVAVMQTPEALYRVAFECAQDLAADSVVYAEVRFAPELHISCGLSFD 120 SGSLE YLE F+HTVAVMQTP L RVA ECA+DLA D VVYAEVRFAPE H+ GLS D Sbjct 61 SGSLELYLETFAHTVAVMQTPVGLRRVARECAEDLADDGVVYAEVRFAPEQHLEGGLSLD 120 Query 121 DVVDTVLTGFAAGEKACAADGQPITVRCLVTAMRHAAMSREIAELAIRFRDKGVVGFDIA 180 DVV+ VL GF GE+ ADG+ I V CL+TAMRHAA SREIAELA+RFRD+GVVGFDIA Sbjct 121 DVVEHVLEGFREGEENARADGREIRVGCLLTAMRHAARSREIAELAVRFRDRGVVGFDIA 180 Query 181 GAEAGHPPTRHLDAFEYMRDHNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDI 240 GAEAG+PP+RHLDAFEYMR NA FTIHAGEAFGLPSIHEAIAFCG DRLGHGVRI DDI Sbjct 181 GAEAGYPPSRHLDAFEYMRASNAHFTIHAGEAFGLPSIHEAIAFCGTDRLGHGVRITDDI 240 Query 241 DVDADGGFQLGRLAAILRDKRIPLELCPSSNVQTGAVASIAEHPFDLLARARFRVTVNTD 300 V DG LG LA +RDKRIPLELCPSSNVQTGAVA++ EHPFDLLAR RFRVTVNTD Sbjct 241 VVGPDGEITLGLLANYVRDKRIPLELCPSSNVQTGAVANLEEHPFDLLARLRFRVTVNTD 300 Query 301 NRLMSDTSMSLEMHRLVEAFGYGWSDLARFTVNAMKSAFIPFDQRLAIIDEVIKPRFAAL 360 NRLMSDT+MS EM LV+ FGYGWSDL RFT+NAMKSAFIPFDQRLA+ID VIKP +A L Sbjct 301 NRLMSDTTMSREMLALVDTFGYGWSDLERFTINAMKSAFIPFDQRLALIDGVIKPGYAVL 360 Query 361 MG 362 +G Sbjct 361 IG 362 >gi|325675592|ref|ZP_08155276.1| adenosine deaminase [Rhodococcus equi ATCC 33707] gi|325553563|gb|EGD23241.1| adenosine deaminase [Rhodococcus equi ATCC 33707] Length=362 Score = 536 bits (1380), Expect = 3e-150, Method: Compositional matrix adjust. Identities = 269/362 (75%), Positives = 295/362 (82%), Gaps = 0/362 (0%) Query 1 MTAAPTLQTIRLAPKALLHDHLDGGLRPATVLDIAGQVGYDDLPATDVDALASWFRTQSH 60 MTA L +R APK LLHDHLDGGLRP TV ++A + GY LPA D LA+WFR + Sbjct 1 MTAPLDLDYLRSAPKVLLHDHLDGGLRPGTVAELADECGYAGLPAETPDGLAAWFRNAAD 60 Query 61 SGSLERYLEPFSHTVAVMQTPEALYRVAFECAQDLAADSVVYAEVRFAPELHISCGLSFD 120 SGSLE YLE F+HTVAVMQTP L RVA ECA+DLA D VVYAEVRFAPE H+ GLS D Sbjct 61 SGSLELYLETFAHTVAVMQTPVGLRRVARECAEDLADDGVVYAEVRFAPEQHLEGGLSLD 120 Query 121 DVVDTVLTGFAAGEKACAADGQPITVRCLVTAMRHAAMSREIAELAIRFRDKGVVGFDIA 180 DVV+ VL GF GE+ ADG+ I V CL+TAMRHAA SREIAELA+RFRD+GVVGFDIA Sbjct 121 DVVEHVLEGFREGEENARADGREIRVGCLLTAMRHAARSREIAELAVRFRDRGVVGFDIA 180 Query 181 GAEAGHPPTRHLDAFEYMRDHNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDI 240 GAEAG+PP+RHLDAFEYMR NA FTIHAGEAFGLPSIHEAIAFCG DRLGHGVRI DDI Sbjct 181 GAEAGYPPSRHLDAFEYMRASNAHFTIHAGEAFGLPSIHEAIAFCGTDRLGHGVRITDDI 240 Query 241 DVDADGGFQLGRLAAILRDKRIPLELCPSSNVQTGAVASIAEHPFDLLARARFRVTVNTD 300 V DG LG LA +RDKRIPLELCPSSNVQTGAVA++ EHPFDLLAR RFRVTVNTD Sbjct 241 VVGPDGEITLGLLANYVRDKRIPLELCPSSNVQTGAVANLEEHPFDLLARLRFRVTVNTD 300 Query 301 NRLMSDTSMSLEMHRLVEAFGYGWSDLARFTVNAMKSAFIPFDQRLAIIDEVIKPRFAAL 360 NRLMSDT+MS EM LV+ FGYGWSDL RFT+NAMKSAFIPFDQRLA+ID VIKP +A L Sbjct 301 NRLMSDTTMSREMLALVDTFGYGWSDLERFTINAMKSAFIPFDQRLALIDGVIKPGYAVL 360 Query 361 MG 362 +G Sbjct 361 IG 362 >gi|296138705|ref|YP_003645948.1| adenosine deaminase [Tsukamurella paurometabola DSM 20162] gi|296026839|gb|ADG77609.1| adenosine deaminase [Tsukamurella paurometabola DSM 20162] Length=375 Score = 530 bits (1365), Expect = 2e-148, Method: Compositional matrix adjust. Identities = 261/364 (72%), Positives = 299/364 (83%), Gaps = 8/364 (2%) Query 7 LQTIRLAPKALLHDHLDGGLRPATVLDIAGQVGYDDLPATDVDALASWFRTQSHSGSLER 66 L ++R APK LLHDHLDGGLRP TVL++A + GY++LPA+ LA+WFR + SGSL + Sbjct 12 LSSLRRAPKVLLHDHLDGGLRPRTVLELAAETGYENLPASTEPELATWFREAADSGSLVK 71 Query 67 YLEPFSHTVAVMQTPEALYRVAFECAQDLAADSVVYAEVRFAPELHISCGLSFDDVVDTV 126 YLE F HTV VMQT +AL RVA ECA+DLAAD VVYAEVRFAPE H GLS D+V++ V Sbjct 72 YLETFEHTVGVMQTSDALRRVARECAEDLAADGVVYAEVRFAPEQHTERGLSLDEVMEAV 131 Query 127 LTGFAAGEKACAADGQPITVRCLVTAMRHAAMSREIAELAIRFRDKGVVGFDIAGAEAGH 186 L+GFA GE A ADG PI VRCLVTAMRHAA SREIAEL +R+RD+G VGFDIAGAEAG Sbjct 132 LSGFAEGEAAAKADGHPIVVRCLVTAMRHAARSREIAELTVRWRDRGAVGFDIAGAEAGF 191 Query 187 PPTRHLDAFEYMRDHNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDI------ 240 PP+RHLDAFEYMRDH+A FTIHAGEAFGLPSIHEA+AFCG DRLGHGVRIVDDI Sbjct 192 PPSRHLDAFEYMRDHSAPFTIHAGEAFGLPSIHEALAFCGCDRLGHGVRIVDDITLPEGV 251 Query 241 --DVDADGGFQLGRLAAILRDKRIPLELCPSSNVQTGAVASIAEHPFDLLARARFRVTVN 298 D G LG +AA +RD RIPLELCPSSNVQT AVAS+ +HPF+LLA+ RFRVTVN Sbjct 252 GLDATDFSGAGLGLVAARVRDARIPLELCPSSNVQTAAVASLEQHPFNLLAQLRFRVTVN 311 Query 299 TDNRLMSDTSMSLEMHRLVEAFGYGWSDLARFTVNAMKSAFIPFDQRLAIIDEVIKPRFA 358 TDNRLMSDTSMSLEM +LV+ FGYGWSDL RFT+NAMKSAF+PFD+RLA+ID+VIKP +A Sbjct 312 TDNRLMSDTSMSLEMLKLVQTFGYGWSDLQRFTINAMKSAFLPFDERLALIDDVIKPGYA 371 Query 359 ALMG 362 L+G Sbjct 372 VLIG 375 >gi|54022920|ref|YP_117162.1| adenosine deaminase [Nocardia farcinica IFM 10152] gi|54014428|dbj|BAD55798.1| putative adenosine deaminase [Nocardia farcinica IFM 10152] Length=365 Score = 524 bits (1349), Expect = 1e-146, Method: Compositional matrix adjust. Identities = 266/358 (75%), Positives = 301/358 (85%), Gaps = 1/358 (0%) Query 6 TLQTIRLAPKALLHDHLDGGLRPATVLDIAGQVGYDDLPATDVDALASWFRTQSHSGSLE 65 TL +IR APKALLHDHLDGGLRPATVL++A + GYD+LPA LA+WFR + SGSLE Sbjct 8 TLASIRRAPKALLHDHLDGGLRPATVLELAAECGYDELPADTEAELAAWFREAADSGSLE 67 Query 66 RYLEPFSHTVAVMQTPEALYRVAFECAQDLAADSVVYAEVRFAPELHISCGLSFDDVVDT 125 RYLE F+HTVAVMQTPE L RVA EC DLAAD VVYAEVR+APE H+ GLS D+VV+ Sbjct 68 RYLETFAHTVAVMQTPEGLRRVARECVLDLAADGVVYAEVRYAPEQHLERGLSLDEVVEH 127 Query 126 VLTGFAAGEKACAADGQPITVRCLVTAMRHAAMSREIAELAIRFRDKGVVGFDIAGAEAG 185 L GF GE+A AA GQPI V CL+TAMRHAA SREIAELA+R+RD+GV GFDIAGAEAG Sbjct 128 TLAGFREGERAAAAAGQPIVVTCLLTAMRHAARSREIAELAVRWRDRGVGGFDIAGAEAG 187 Query 186 HPPTRHLDAFEYMRDHNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDIDV-DA 244 +PPTRHLDAFEYMR ++A FTIHAGEAFGLPSIHEA+AFCG DRLGHGVRI DDI V D+ Sbjct 188 YPPTRHLDAFEYMRANSAHFTIHAGEAFGLPSIHEALAFCGCDRLGHGVRITDDIRVGDS 247 Query 245 DGGFQLGRLAAILRDKRIPLELCPSSNVQTGAVASIAEHPFDLLARARFRVTVNTDNRLM 304 +LG +A +RDKRIPLELCPSSNVQTGAV S+ +HPFDLLAR RFRVTVNTDNRLM Sbjct 248 VADAELGLVARYVRDKRIPLELCPSSNVQTGAVPSLDKHPFDLLARLRFRVTVNTDNRLM 307 Query 305 SDTSMSLEMHRLVEAFGYGWSDLARFTVNAMKSAFIPFDQRLAIIDEVIKPRFAALMG 362 SDTSMS EMH+LV+ FGYGWSDL RFT+NAMKSAFIPF +RL IID++IKP +A L+G Sbjct 308 SDTSMSQEMHKLVQTFGYGWSDLERFTINAMKSAFIPFPERLRIIDDIIKPGYAVLIG 365 >gi|262201724|ref|YP_003272932.1| adenosine deaminase [Gordonia bronchialis DSM 43247] gi|262085071|gb|ACY21039.1| adenosine deaminase [Gordonia bronchialis DSM 43247] Length=369 Score = 520 bits (1339), Expect = 1e-145, Method: Compositional matrix adjust. Identities = 265/364 (73%), Positives = 299/364 (83%), Gaps = 8/364 (2%) Query 7 LQTIRLAPKALLHDHLDGGLRPATVLDIAGQVGYDDLPATDVDALASWFRTQSHSGSLER 66 L I LAPK LLHDHLDGGLRPATVL++A Q GY+ LPA DVD+LA WFR + SGSLER Sbjct 6 LANISLAPKVLLHDHLDGGLRPATVLELAEQSGYEGLPAHDVDSLARWFREAADSGSLER 65 Query 67 YLEPFSHTVAVMQTPEALYRVAFECAQDLAADSVVYAEVRFAPELHISCGLSFDDVVDTV 126 YLE F+HTV VMQT +AL RVA EC DLAAD VVYAE+R+APE H+ GL+ +VV+ V Sbjct 66 YLETFAHTVGVMQTVDALERVARECVADLAADGVVYAEIRYAPEQHLQQGLTLAEVVEAV 125 Query 127 LTGFAAGEKACAADGQPITVRCLVTAMRHAAMSREIAELAIRFRDKGVVGFDIAGAEAGH 186 L GFA GE AA G+PITVRCLVTAMRHAA SREIAELA+R+R +GVVGFDIAGAEAGH Sbjct 126 LRGFADGEAEAAAAGKPITVRCLVTAMRHAARSREIAELAVRYRRRGVVGFDIAGAEAGH 185 Query 187 PPTRHLDAFEYMRDHNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDIDV---- 242 PPTRHLDAFEYMR +NA FTIHAGEAFGLPSIHEAI FCG DRLGHGVR++DDI++ Sbjct 186 PPTRHLDAFEYMRANNAPFTIHAGEAFGLPSIHEAIGFCGTDRLGHGVRVIDDIELPDGT 245 Query 243 ----DADGGFQLGRLAAILRDKRIPLELCPSSNVQTGAVASIAEHPFDLLARARFRVTVN 298 D+ G LG +A I+RDKRIPLELCPSSNVQTGAVASIAEHPF++LAR RFRVTVN Sbjct 246 DLAADSFAGATLGDIANIVRDKRIPLELCPSSNVQTGAVASIAEHPFNILARLRFRVTVN 305 Query 299 TDNRLMSDTSMSLEMHRLVEAFGYGWSDLARFTVNAMKSAFIPFDQRLAIIDEVIKPRFA 358 TDNRLMSDT+MS E +L FGYGW+D RFTVNAMKSAFI FD+RLA ID+VIKP +A Sbjct 306 TDNRLMSDTTMSNEFLQLSRQFGYGWADFERFTVNAMKSAFIHFDERLAFIDDVIKPGYA 365 Query 359 ALMG 362 L+G Sbjct 366 VLIG 369 >gi|343926659|ref|ZP_08766157.1| adenosine deaminase [Gordonia alkanivorans NBRC 16433] gi|343763411|dbj|GAA13083.1| adenosine deaminase [Gordonia alkanivorans NBRC 16433] Length=371 Score = 514 bits (1323), Expect = 1e-143, Method: Compositional matrix adjust. Identities = 255/362 (71%), Positives = 294/362 (82%), Gaps = 10/362 (2%) Query 10 IRLAPKALLHDHLDGGLRPATVLDIAGQVGYDDLPATDVDALASWFRTQSHSGSLERYLE 69 + LAPK LLHDHLDGGLRPATVL++A VGYD LP D L WFR + SGSLERYLE Sbjct 9 LTLAPKVLLHDHLDGGLRPATVLELAHDVGYDGLPVDDAVGLGRWFREAADSGSLERYLE 68 Query 70 PFSHTVAVMQTPEALYRVAFECAQDLAADSVVYAEVRFAPELHISCGLSFDDVVDTVLTG 129 F+HTVAVMQT +AL RVA EC +DLA D+VVYAEVR+APE H+ GL+ D+VV+ VL G Sbjct 69 TFTHTVAVMQTVDALERVARECVEDLADDNVVYAEVRYAPEQHLEAGLTLDEVVEAVLRG 128 Query 130 FAAGEKACAADGQPITVRCLVTAMRHAAMSREIAELAIRFRDKGVVGFDIAGAEAGHPPT 189 FA GE+ A G+ I VRCLVTAMRHAA SREIAELA+R+RD+GVVGFDIAGAEAGHPPT Sbjct 129 FADGERIAADRGKTIIVRCLVTAMRHAARSREIAELAVRYRDRGVVGFDIAGAEAGHPPT 188 Query 190 RHLDAFEYMRDHNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDIDVDADG--- 246 RHLDAFEYMR ++A FTIHAGEAFGLPSIHEAI FCG DRLGHGVR+ DD+++ DG Sbjct 189 RHLDAFEYMRANSAPFTIHAGEAFGLPSIHEAIGFCGTDRLGHGVRVFDDVEL-PDGVDL 247 Query 247 ------GFQLGRLAAILRDKRIPLELCPSSNVQTGAVASIAEHPFDLLARARFRVTVNTD 300 G +LG +A I+RDKRIPLELCPSSNVQTGAV+S+AEHPF++LAR RFRVTVNTD Sbjct 248 AAHSFTGAKLGLIANIVRDKRIPLELCPSSNVQTGAVSSLAEHPFNVLARLRFRVTVNTD 307 Query 301 NRLMSDTSMSLEMHRLVEAFGYGWSDLARFTVNAMKSAFIPFDQRLAIIDEVIKPRFAAL 360 NRLM DT+MS E L + FGYGW+D RFTVNAMKSAFI FD+RL +ID+VIKP +A L Sbjct 308 NRLMGDTTMSKEFGLLADQFGYGWADFERFTVNAMKSAFIHFDERLDVIDDVIKPGYAVL 367 Query 361 MG 362 +G Sbjct 368 LG 369 >gi|333921527|ref|YP_004495108.1| adenosine deaminase [Amycolicicoccus subflavus DQS3-9A1] gi|333483748|gb|AEF42308.1| Adenosine deaminase [Amycolicicoccus subflavus DQS3-9A1] Length=367 Score = 512 bits (1318), Expect = 4e-143, Method: Compositional matrix adjust. Identities = 257/367 (71%), Positives = 295/367 (81%), Gaps = 5/367 (1%) Query 1 MTAAP-TLQTIRLAPKALLHDHLDGGLRPATVLDIAGQVGYDDLPATDVDALASWFRTQS 59 MT P L ++RLAPK LLHDHLDGGLRP TVLD+A GY DLPA + + L WFR + Sbjct 1 MTHTPINLASLRLAPKVLLHDHLDGGLRPQTVLDLARDCGYTDLPADNPEELRVWFRDAA 60 Query 60 HSGSLERYLEPFSHTVAVMQTPEALYRVAFECAQDLAADSVVYAEVRFAPELHISCGLSF 119 SGSLE YL+ F HTVAVMQTP AL RVA EC +DLAAD VVYAEVRFAPE H+ GL+ Sbjct 61 DSGSLELYLQTFGHTVAVMQTPAALARVARECVEDLAADGVVYAEVRFAPEQHLDAGLNL 120 Query 120 DDVVDTVLTGFAAGEKACA-ADGQPITVRCLVTAMRHAAMSREIAELAIRFRDKGVVGFD 178 D V+++ L+GFA G +A G I VRCLVTAMRHAA SREIAELA+++R GV GFD Sbjct 121 DAVMESTLSGFAEGVRAVRDQSGHDIVVRCLVTAMRHAARSREIAELAVKYRHDGVCGFD 180 Query 179 IAGAEAGHPPTRHLDAFEYMRDHNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVD 238 IAGAEAG PP+RHLDAFE+++ NA FTIHAGEAFGLPSIHEA+AFCGADRLGHGVRI+D Sbjct 181 IAGAEAGFPPSRHLDAFEFLQKENAHFTIHAGEAFGLPSIHEAVAFCGADRLGHGVRIMD 240 Query 239 DIDVDADGGF---QLGRLAAILRDKRIPLELCPSSNVQTGAVASIAEHPFDLLARARFRV 295 DI++ +G F +LG LA +RDKRIPLELCPSSNVQTGA ASIAEHPF+ LA+ +FRV Sbjct 241 DIELGPEGTFGEAKLGLLANYIRDKRIPLELCPSSNVQTGAAASIAEHPFNQLAQLQFRV 300 Query 296 TVNTDNRLMSDTSMSLEMHRLVEAFGYGWSDLARFTVNAMKSAFIPFDQRLAIIDEVIKP 355 TVNTDNRLMS T+MS EM +LVE FGYGWSDL RFT+NAMKSAF FD+RLAIIDEVIKP Sbjct 301 TVNTDNRLMSHTTMSEEMLKLVETFGYGWSDLERFTINAMKSAFYSFDKRLAIIDEVIKP 360 Query 356 RFAALMG 362 +A L+G Sbjct 361 GYAVLIG 367 >gi|326381953|ref|ZP_08203646.1| adenosine deaminase [Gordonia neofelifaecis NRRL B-59395] gi|326199379|gb|EGD56560.1| adenosine deaminase [Gordonia neofelifaecis NRRL B-59395] Length=372 Score = 508 bits (1308), Expect = 6e-142, Method: Compositional matrix adjust. Identities = 262/365 (72%), Positives = 299/365 (82%), Gaps = 8/365 (2%) Query 6 TLQTIRLAPKALLHDHLDGGLRPATVLDIAGQVGYDDLPATDVDALASWFRTQSHSGSLE 65 T RLAPK LLHDHLDGGLRP+TVLD+A + GYD LPA D LA WF T + SGSLE Sbjct 8 TADECRLAPKVLLHDHLDGGLRPSTVLDLARRQGYDALPADTADDLAEWFATAADSGSLE 67 Query 66 RYLEPFSHTVAVMQTPEALYRVAFECAQDLAADSVVYAEVRFAPELHISCGLSFDDVVDT 125 RYLE F+HTVAVMQ+ AL RVA EC +DL AD VVYAEVRFAPELH+ GLS D+VV Sbjct 68 RYLETFAHTVAVMQSAGALERVARECVEDLHADGVVYAEVRFAPELHLEAGLSLDEVVVA 127 Query 126 VLTGFAAGEKACAADGQPITVRCLVTAMRHAAMSREIAELAIRFRDKGVVGFDIAGAEAG 185 VL GFA+GE+A AA G+PI VRCLVTAMRHAA SREIAELA+RFR +GVVGFDIAGAEAG Sbjct 128 VLRGFASGEEAAAASGRPIIVRCLVTAMRHAARSREIAELAVRFRGRGVVGFDIAGAEAG 187 Query 186 HPPTRHLDAFEYMRDHNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDIDVDAD 245 +PP+RHLDAFEY+R + FTIHAGEAFGLPSIHEA+AFCG DRLGHGVR++DDI + A Sbjct 188 NPPSRHLDAFEYLRGECSHFTIHAGEAFGLPSIHEAVAFCGTDRLGHGVRVIDDIVLPAG 247 Query 246 --------GGFQLGRLAAILRDKRIPLELCPSSNVQTGAVASIAEHPFDLLARARFRVTV 297 GG +LGR+A +RDKRIPLELCPSSNVQTGAVAS+A+HPF++LA+ RFRVTV Sbjct 248 AAPTDPSFGGAKLGRVADYVRDKRIPLELCPSSNVQTGAVASLADHPFNILAKLRFRVTV 307 Query 298 NTDNRLMSDTSMSLEMHRLVEAFGYGWSDLARFTVNAMKSAFIPFDQRLAIIDEVIKPRF 357 NTDNRLMS+T+MS E L + FGYGW+D RFTVNAMKSAF+PFD+RL +IDEVIKP F Sbjct 308 NTDNRLMSNTTMSREFMVLHQQFGYGWADFERFTVNAMKSAFLPFDERLRLIDEVIKPGF 367 Query 358 AALMG 362 A LMG Sbjct 368 AVLMG 372 >gi|271962824|ref|YP_003337020.1| adenosine deaminase [Streptosporangium roseum DSM 43021] gi|270505999|gb|ACZ84277.1| Adenosine deaminase [Streptosporangium roseum DSM 43021] Length=359 Score = 506 bits (1303), Expect = 2e-141, Method: Compositional matrix adjust. Identities = 247/360 (69%), Positives = 287/360 (80%), Gaps = 5/360 (1%) Query 1 MTAAPTLQTIRLAPKALLHDHLDGGLRPATVLDIAGQVGYDDLPATDVDALASWFRTQSH 60 M+ PTL+ IR APK LLHDHLDGGLRP T++++A GYD LP TDVD L +WFR S Sbjct 1 MSQLPTLEEIRRAPKVLLHDHLDGGLRPETIVELAAGSGYDRLPTTDVDGLRTWFREASD 60 Query 61 SGSLERYLEPFSHTVAVMQTPEALYRVAFECAQDLAADSVVYAEVRFAPELHISCGLSFD 120 SGSLERYLE F HTV VMQT E+L RVA ECA+DLAAD VVYAEVR+APE H S GLS + Sbjct 61 SGSLERYLETFDHTVGVMQTRESLVRVAAECAEDLAADGVVYAEVRYAPEQHTSAGLSLE 120 Query 121 DVVDTVLTGFAAGEKACAADGQPITVRCLVTAMRHAAMSREIAELAIRFRDKGVVGFDIA 180 +V++ V GF AG ++G+ I V L+TAMRH A SREIAELA+R+RD GV GFDIA Sbjct 121 EVIEAVQEGFRAG-----SEGRGIRVGTLLTAMRHQARSREIAELAVRYRDVGVAGFDIA 175 Query 181 GAEAGHPPTRHLDAFEYMRDHNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDI 240 GAEAG+PPTRHLDAFEY++ NA FTIHAGEAFGLPSI +AI +CGADRLGHGVRI+DDI Sbjct 176 GAEAGYPPTRHLDAFEYLQRENAHFTIHAGEAFGLPSIWQAIQWCGADRLGHGVRIIDDI 235 Query 241 DVDADGGFQLGRLAAILRDKRIPLELCPSSNVQTGAVASIAEHPFDLLARARFRVTVNTD 300 V +G +LGRLAA +RDKRIPLE+CP+SN+QTGA SIAEHP LL R FRVTVNTD Sbjct 236 TVSGEGEAKLGRLAAYVRDKRIPLEMCPTSNLQTGAATSIAEHPIGLLRRLNFRVTVNTD 295 Query 301 NRLMSDTSMSLEMHRLVEAFGYGWSDLARFTVNAMKSAFIPFDQRLAIIDEVIKPRFAAL 360 NRLMS TS+S E +L EAFGYGW D+ FT+NAMKSAF+PFD+RLA+I+ VIKP FA L Sbjct 296 NRLMSGTSVSEEFAKLSEAFGYGWDDMQWFTINAMKSAFLPFDERLALINGVIKPGFARL 355 >gi|296268670|ref|YP_003651302.1| adenosine deaminase [Thermobispora bispora DSM 43833] gi|296091457|gb|ADG87409.1| adenosine deaminase [Thermobispora bispora DSM 43833] Length=362 Score = 501 bits (1289), Expect = 1e-139, Method: Compositional matrix adjust. Identities = 253/361 (71%), Positives = 288/361 (80%), Gaps = 4/361 (1%) Query 1 MTAAPTLQTIRLAPKALLHDHLDGGLRPATVLDIAGQVGYDDLPATDVDALASWFRTQSH 60 MT PTL+ IR APK LLHDHLDGGLRP T++++A + G+ LP+TD D LA WFR + Sbjct 1 MTQTPTLEEIRKAPKVLLHDHLDGGLRPETIIELARERGHR-LPSTDPDNLAEWFRESAD 59 Query 61 SGSLERYLEPFSHTVAVMQTPEALYRVAFECAQDLAADSVVYAEVRFAPELHISCGLSFD 120 SGSLERYL+ F+HTVAVMQT EAL RVA ECA+DLA D +VYAEVR+APELH GL+ D Sbjct 60 SGSLERYLDTFTHTVAVMQTREALTRVAAECAEDLADDGIVYAEVRYAPELHTDGGLTLD 119 Query 121 DVVDTVLTGFAAGEKACAADG-QPITVRCLVTAMRHAAMSREIAELAIRFRDKGVVGFDI 179 +VV+ VL GF G + DG Q I V L+TAMRH A S EIAELA+R+RD GVVGFDI Sbjct 120 EVVEAVLEGFRIG--STGPDGRQRIRVGTLLTAMRHQARSMEIAELAVRYRDAGVVGFDI 177 Query 180 AGAEAGHPPTRHLDAFEYMRDHNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDD 239 AGAEAG+PPTRHLDAFEY++ NA FTIHAGE FGLPSI +AI +CGADRLGHGVRI+DD Sbjct 178 AGAEAGYPPTRHLDAFEYLKRENAHFTIHAGEGFGLPSIWQAIQWCGADRLGHGVRIIDD 237 Query 240 IDVDADGGFQLGRLAAILRDKRIPLELCPSSNVQTGAVASIAEHPFDLLARARFRVTVNT 299 I V DG LGRLAA +RDKRIPLE+CP+SNVQTGA SIAEHP LL R FRVTVNT Sbjct 238 ITVADDGTVTLGRLAAYVRDKRIPLEMCPTSNVQTGAAKSIAEHPIGLLRRLCFRVTVNT 297 Query 300 DNRLMSDTSMSLEMHRLVEAFGYGWSDLARFTVNAMKSAFIPFDQRLAIIDEVIKPRFAA 359 DNRLMS TS+SLE +LVEAFGYGW DL FTVNAMKSAFIPFD+RLA+I+ VIKP FA Sbjct 298 DNRLMSGTSLSLEFAKLVEAFGYGWDDLQWFTVNAMKSAFIPFDERLALINGVIKPGFAQ 357 Query 360 L 360 L Sbjct 358 L 358 >gi|297201973|ref|ZP_06919370.1| adenosine deaminase [Streptomyces sviceus ATCC 29083] gi|197712646|gb|EDY56680.1| adenosine deaminase [Streptomyces sviceus ATCC 29083] Length=387 Score = 492 bits (1267), Expect = 4e-137, Method: Compositional matrix adjust. Identities = 242/360 (68%), Positives = 279/360 (78%), Gaps = 0/360 (0%) Query 1 MTAAPTLQTIRLAPKALLHDHLDGGLRPATVLDIAGQVGYDDLPATDVDALASWFRTQSH 60 M +P+ IR APK LLHDHLDGGLRP T++D+A GY LP TD D L WFR + Sbjct 8 MGNSPSSDQIRRAPKVLLHDHLDGGLRPGTIVDLARDAGYTGLPETDADRLGVWFREAAD 67 Query 61 SGSLERYLEPFSHTVAVMQTPEALYRVAFECAQDLAADSVVYAEVRFAPELHISCGLSFD 120 SGSLERYLE FSHTV VMQT EAL RVA ECA+DLA D VVYAEVR+APE H+ GL+ + Sbjct 68 SGSLERYLETFSHTVGVMQTREALTRVAAECAEDLAEDGVVYAEVRYAPEQHLQKGLTLE 127 Query 121 DVVDTVLTGFAAGEKACAADGQPITVRCLVTAMRHAAMSREIAELAIRFRDKGVVGFDIA 180 +VV+ V GF GE+ A+G I V L+TAMRHAA + EIAELA R+RD GVVGFDIA Sbjct 128 EVVEAVNEGFREGERRARANGHRIRVGALLTAMRHAARALEIAELANRYRDLGVVGFDIA 187 Query 181 GAEAGHPPTRHLDAFEYMRDHNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDI 240 GAEAG+PPTRHLDAFEY++ N FTIHAGEAFGLPSI +A+ +CGADRLGHGVRI+DDI Sbjct 188 GAEAGYPPTRHLDAFEYLKRENNHFTIHAGEAFGLPSIWQALQWCGADRLGHGVRIIDDI 247 Query 241 DVDADGGFQLGRLAAILRDKRIPLELCPSSNVQTGAVASIAEHPFDLLARARFRVTVNTD 300 V DG +LGRLA+ +RDKRIPLELCPSSN+QTGA +S AEHP LL R FR TVNTD Sbjct 248 QVHEDGTVKLGRLASYVRDKRIPLELCPSSNLQTGAASSYAEHPIGLLRRLHFRATVNTD 307 Query 301 NRLMSDTSMSLEMHRLVEAFGYGWSDLARFTVNAMKSAFIPFDQRLAIIDEVIKPRFAAL 360 NRLMS TSMS E LVEAFGY D+ F+VNAMKSAFIPFD+RLA+I++VIKP +A L Sbjct 308 NRLMSGTSMSREFEHLVEAFGYSLDDMQWFSVNAMKSAFIPFDERLAMINDVIKPGYAEL 367 >gi|329935635|ref|ZP_08285442.1| adenosine deaminase [Streptomyces griseoaurantiacus M045] gi|329304896|gb|EGG48767.1| adenosine deaminase [Streptomyces griseoaurantiacus M045] Length=371 Score = 492 bits (1267), Expect = 4e-137, Method: Compositional matrix adjust. Identities = 243/356 (69%), Positives = 276/356 (78%), Gaps = 0/356 (0%) Query 5 PTLQTIRLAPKALLHDHLDGGLRPATVLDIAGQVGYDDLPATDVDALASWFRTQSHSGSL 64 P+ IR APK LLHDHLDGGLRP TV ++A GY LP TD D L WFR + SGSL Sbjct 9 PSSDQIRRAPKVLLHDHLDGGLRPGTVAELARATGYSGLPETDADKLGLWFREAADSGSL 68 Query 65 ERYLEPFSHTVAVMQTPEALYRVAFECAQDLAADSVVYAEVRFAPELHISCGLSFDDVVD 124 ERYLE FSHTV VMQT EAL RVA ECA+DLA D VVYAEVR+APE H+ GL+ ++VV+ Sbjct 69 ERYLETFSHTVGVMQTREALVRVAAECAEDLAEDGVVYAEVRYAPEQHLEGGLTLEEVVE 128 Query 125 TVLTGFAAGEKACAADGQPITVRCLVTAMRHAAMSREIAELAIRFRDKGVVGFDIAGAEA 184 V GF GE+ +G I V L+TAMRHAA S EIAELA R+RD GVVGFDIAGAEA Sbjct 129 AVNEGFREGERRARENGHRIRVGALLTAMRHAARSLEIAELANRYRDLGVVGFDIAGAEA 188 Query 185 GHPPTRHLDAFEYMRDHNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDIDVDA 244 GHPPTRHLDAFEY++ N FTIHAGEAFGLPSI +A+ +CGADRLGHGVRI+DDI+V Sbjct 189 GHPPTRHLDAFEYLKRENNHFTIHAGEAFGLPSIWQALQWCGADRLGHGVRIIDDIEVRE 248 Query 245 DGGFQLGRLAAILRDKRIPLELCPSSNVQTGAVASIAEHPFDLLARARFRVTVNTDNRLM 304 DG LGRLAA +RDKR+PLELCPSSN+QTGA AS AEHP LL R FR TVNTDNRLM Sbjct 249 DGSVHLGRLAAYVRDKRVPLELCPSSNLQTGAAASYAEHPIGLLRRLHFRATVNTDNRLM 308 Query 305 SDTSMSLEMHRLVEAFGYGWSDLARFTVNAMKSAFIPFDQRLAIIDEVIKPRFAAL 360 S TSMS E LV+AFGY D+ F+VNAMKSAFIPFD+RLA+I++VIKPR+A L Sbjct 309 SGTSMSREFEHLVDAFGYTLDDMQWFSVNAMKSAFIPFDERLAMINDVIKPRYAEL 364 >gi|302865289|ref|YP_003833926.1| adenosine deaminase [Micromonospora aurantiaca ATCC 27029] gi|302568148|gb|ADL44350.1| adenosine deaminase [Micromonospora aurantiaca ATCC 27029] Length=358 Score = 491 bits (1264), Expect = 8e-137, Method: Compositional matrix adjust. Identities = 252/359 (71%), Positives = 283/359 (79%), Gaps = 3/359 (0%) Query 4 APTLQTIRLAPKALLHDHLDGGLRPATVLDIAGQVGYDDLPATDVDALASWFRTQSHSGS 63 A + + I PKALLHDHLDGGLRPAT++++A +VG++ LP TD AL WF ++SGS Sbjct 3 AISYEDIVKVPKALLHDHLDGGLRPATIVELAAEVGHE-LPTTDPAALGVWFTEAANSGS 61 Query 64 LERYLEPFSHTVAVMQTPEALYRVAFECAQDLAADSVVYAEVRFAPELHISCGLSFDDVV 123 LERYLE F+HTVAVMQTP AL RVA ECA DLAAD VVYAEVRFAPE H+ L+ D+VV Sbjct 62 LERYLETFAHTVAVMQTPAALRRVARECALDLAADGVVYAEVRFAPEQHLEQNLTLDEVV 121 Query 124 DTVLTGFAAGEKACAADGQPITVRCLVTAMRHAAMSREIAELAIRFRDKGVVGFDIAGAE 183 D V+TGF G A G PI + L+TAMRHAA S+EIAELA+R RD GVVGFDIAGAE Sbjct 122 DAVVTGFREGSALAAEAGTPIRIGTLLTAMRHAARSQEIAELAVRHRDTGVVGFDIAGAE 181 Query 184 AGHPPTRHLDAFEYMRDHNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDIDVD 243 AG PPTRHLDAFEY++ N FTIHAGEAFGLPSI +AI +CGADRLGHGVRIVDDI Sbjct 182 AGFPPTRHLDAFEYLQRENFHFTIHAGEAFGLPSIWQAIQWCGADRLGHGVRIVDDI--T 239 Query 244 ADGGFQLGRLAAILRDKRIPLELCPSSNVQTGAVASIAEHPFDLLARARFRVTVNTDNRL 303 LGRLAA +RDKRIPLELCPSSNVQTGA ASIA+HP LL RFRVTVNTDNRL Sbjct 240 PGNPPVLGRLAAYVRDKRIPLELCPSSNVQTGAAASIADHPIGLLRDLRFRVTVNTDNRL 299 Query 304 MSDTSMSLEMHRLVEAFGYGWSDLARFTVNAMKSAFIPFDQRLAIIDEVIKPRFAALMG 362 MS TSMS EM LVEAFGYGW +L FT+NAMKSAFIPFD+RL IIDEVIKP +A L+G Sbjct 300 MSGTSMSREMSLLVEAFGYGWKELQWFTINAMKSAFIPFDERLRIIDEVIKPAYAELIG 358 >gi|21223275|ref|NP_629054.1| adenosine deaminase [Streptomyces coelicolor A3(2)] gi|289769515|ref|ZP_06528893.1| adenosine deaminase [Streptomyces lividans TK24] gi|20137451|sp|Q9AK25.1|ADD1_STRCO RecName: Full=Adenosine deaminase 1; AltName: Full=Adenosine aminohydrolase 1 gi|13162090|emb|CAC33066.1| putative adenosine deaminase [Streptomyces coelicolor A3(2)] gi|289699714|gb|EFD67143.1| adenosine deaminase [Streptomyces lividans TK24] Length=396 Score = 490 bits (1262), Expect = 1e-136, Method: Compositional matrix adjust. Identities = 240/360 (67%), Positives = 280/360 (78%), Gaps = 0/360 (0%) Query 1 MTAAPTLQTIRLAPKALLHDHLDGGLRPATVLDIAGQVGYDDLPATDVDALASWFRTQSH 60 ++ P+ IR APK LLHDHLDGGLRP T++++A + GY DLP TD D L +WFR + Sbjct 17 VSKTPSPDRIRRAPKVLLHDHLDGGLRPGTIVELARETGYGDLPETDADLLGTWFRQAAD 76 Query 61 SGSLERYLEPFSHTVAVMQTPEALYRVAFECAQDLAADSVVYAEVRFAPELHISCGLSFD 120 SGSLERYLE FSHTV VMQT +AL RVA ECA+DLA D VVYAEVR+APE H+ GL+ + Sbjct 77 SGSLERYLETFSHTVGVMQTRDALVRVAAECAEDLAEDGVVYAEVRYAPEQHLEKGLTLE 136 Query 121 DVVDTVLTGFAAGEKACAADGQPITVRCLVTAMRHAAMSREIAELAIRFRDKGVVGFDIA 180 +VV+ V GF GE+ +G I V L+TAMRHAA S EIAELA R+RD GVVGFDIA Sbjct 137 EVVEAVNEGFREGERRARDNGHRIRVGALLTAMRHAARSLEIAELANRYRDLGVVGFDIA 196 Query 181 GAEAGHPPTRHLDAFEYMRDHNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDI 240 GAEAG+PPTRHLDAFEY++ N FTIHAGEAFGLPSI +A+ +CGADRLGHGVRI+DDI Sbjct 197 GAEAGYPPTRHLDAFEYLKRENNHFTIHAGEAFGLPSIWQALQWCGADRLGHGVRIIDDI 256 Query 241 DVDADGGFQLGRLAAILRDKRIPLELCPSSNVQTGAVASIAEHPFDLLARARFRVTVNTD 300 V DG +LGRLA+ +RDKRIPLELCPSSN+QTGA S AEHP LL R FR TVNTD Sbjct 257 QVHEDGSVKLGRLASYVRDKRIPLELCPSSNLQTGAADSYAEHPIGLLRRLHFRATVNTD 316 Query 301 NRLMSDTSMSLEMHRLVEAFGYGWSDLARFTVNAMKSAFIPFDQRLAIIDEVIKPRFAAL 360 NRLMS TSMS E LVEAFGY D+ F+VNAMKSAFIPFD+RLA+I++VIKP +A L Sbjct 317 NRLMSHTSMSREFEHLVEAFGYTLDDMQWFSVNAMKSAFIPFDERLAMINDVIKPGYAEL 376 >gi|315501833|ref|YP_004080720.1| adenosine deaminase [Micromonospora sp. L5] gi|315408452|gb|ADU06569.1| adenosine deaminase [Micromonospora sp. L5] Length=358 Score = 490 bits (1261), Expect = 2e-136, Method: Compositional matrix adjust. Identities = 252/359 (71%), Positives = 283/359 (79%), Gaps = 3/359 (0%) Query 4 APTLQTIRLAPKALLHDHLDGGLRPATVLDIAGQVGYDDLPATDVDALASWFRTQSHSGS 63 A + + I PKALLHDHLDGGLRPAT++++A +VG++ LP TD AL WF ++SGS Sbjct 3 AISYEDIVKVPKALLHDHLDGGLRPATIVELAAEVGHE-LPTTDPAALGVWFTEAANSGS 61 Query 64 LERYLEPFSHTVAVMQTPEALYRVAFECAQDLAADSVVYAEVRFAPELHISCGLSFDDVV 123 LERYLE F+HTVAVMQTP AL RVA ECA DLAAD VVYAEVRFAPE H+ L+ D+VV Sbjct 62 LERYLETFAHTVAVMQTPAALRRVARECALDLAADGVVYAEVRFAPEQHLEQNLTLDEVV 121 Query 124 DTVLTGFAAGEKACAADGQPITVRCLVTAMRHAAMSREIAELAIRFRDKGVVGFDIAGAE 183 D V+TGF G A G PI + L+TAMRHAA S+EIAELA+R RD GVVGFDIAGAE Sbjct 122 DAVVTGFREGSALAAEAGTPIRIGTLLTAMRHAARSQEIAELAVRHRDTGVVGFDIAGAE 181 Query 184 AGHPPTRHLDAFEYMRDHNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDIDVD 243 AG PPTRHLDAFEY++ N FTIHAGEAFGLPSI +AI +CGADRLGHGVRIVDDI Sbjct 182 AGFPPTRHLDAFEYLQRENFHFTIHAGEAFGLPSIWQAIQWCGADRLGHGVRIVDDI--T 239 Query 244 ADGGFQLGRLAAILRDKRIPLELCPSSNVQTGAVASIAEHPFDLLARARFRVTVNTDNRL 303 LGRLAA +RDKRIPLELCPSSNVQTGA ASIA+HP LL RFRVTVNTDNRL Sbjct 240 PGNPPVLGRLAAYVRDKRIPLELCPSSNVQTGAAASIADHPIGLLRDLRFRVTVNTDNRL 299 Query 304 MSDTSMSLEMHRLVEAFGYGWSDLARFTVNAMKSAFIPFDQRLAIIDEVIKPRFAALMG 362 MS TSMS EM LVEAFGYGW +L FT+NAMKSAFIPFD+RL IIDEVIKP +A L+G Sbjct 300 MSGTSMSREMALLVEAFGYGWKELQWFTINAMKSAFIPFDERLRIIDEVIKPAYAELIG 358 >gi|312199932|ref|YP_004019993.1| adenosine deaminase [Frankia sp. EuI1c] gi|311231268|gb|ADP84123.1| adenosine deaminase [Frankia sp. EuI1c] Length=361 Score = 489 bits (1260), Expect = 2e-136, Method: Compositional matrix adjust. Identities = 245/358 (69%), Positives = 279/358 (78%), Gaps = 5/358 (1%) Query 3 AAPTLQTIRLAPKALLHDHLDGGLRPATVLDIAGQVGYDDLPATDVDALASWFRTQSHSG 62 A+ TL IRLAPK LLHDHLDGGLRPATV+++A + GY LP TDV L WFR +HSG Sbjct 2 ASLTLDQIRLAPKVLLHDHLDGGLRPATVVELADECGYTALPTTDVTKLGGWFRGGAHSG 61 Query 63 SLERYLEPFSHTVAVMQTPEALYRVAFECAQDLAADSVVYAEVRFAPELHISCGLSFDDV 122 SL RYLE FSHTVAVMQTPEAL RVA ECA+DLAAD +VYAE+RFAPELH GLS D + Sbjct 62 SLVRYLETFSHTVAVMQTPEALARVARECAEDLAADGIVYAEIRFAPELHTENGLSLDAI 121 Query 123 VDTVLTGFAAGEKACAADGQPITVRCLVTAMRHAAMSREIAELAIRFRDKGVVGFDIAGA 182 V+ VL G AG ++G + R L TAMRH A S EIAELA+R+RD+GVVGFDIAGA Sbjct 122 VEAVLDGLRAG-----SEGTGLHARVLCTAMRHQARSLEIAELAVRWRDQGVVGFDIAGA 176 Query 183 EAGHPPTRHLDAFEYMRDHNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDIDV 242 EAG+PPTRHLDAF+Y++ N FTIHAGEAFGLPSI EA+ +C ADRLGHGVRIVDDI V Sbjct 177 EAGNPPTRHLDAFQYLQRANGHFTIHAGEAFGLPSIWEAVQWCNADRLGHGVRIVDDISV 236 Query 243 DADGGFQLGRLAAILRDKRIPLELCPSSNVQTGAVASIAEHPFDLLARARFRVTVNTDNR 302 D +G LG LA +RD R+PLE+CPSSNV TGA SIA HP LL RFRVTVNTDNR Sbjct 237 DVEGQASLGPLANYVRDTRVPLEMCPSSNVHTGAARSIATHPIGLLRDLRFRVTVNTDNR 296 Query 303 LMSDTSMSLEMHRLVEAFGYGWSDLARFTVNAMKSAFIPFDQRLAIIDEVIKPRFAAL 360 LMSD ++S E LVE FGYGWSD+ FT+NAMKSAF+PFDQRL +ID+VIKP F AL Sbjct 297 LMSDVTLSSEFATLVETFGYGWSDIRWFTLNAMKSAFLPFDQRLDLIDDVIKPGFDAL 354 >gi|302558808|ref|ZP_07311150.1| adenosine deaminase [Streptomyces griseoflavus Tu4000] gi|302476426|gb|EFL39519.1| adenosine deaminase [Streptomyces griseoflavus Tu4000] Length=385 Score = 489 bits (1260), Expect = 2e-136, Method: Compositional matrix adjust. Identities = 243/357 (69%), Positives = 280/357 (79%), Gaps = 0/357 (0%) Query 4 APTLQTIRLAPKALLHDHLDGGLRPATVLDIAGQVGYDDLPATDVDALASWFRTQSHSGS 63 APT IR APK LLHDHLDGGLRP TV+D+A + GY LP TD D LA WFR + SGS Sbjct 9 APTADQIRRAPKVLLHDHLDGGLRPGTVVDLAARNGYLQLPETDPDKLALWFREAADSGS 68 Query 64 LERYLEPFSHTVAVMQTPEALYRVAFECAQDLAADSVVYAEVRFAPELHISCGLSFDDVV 123 LERYLE FSHTV VMQT +AL RVA ECA+DLA D VVYAEVR+APE H+ GL+ ++VV Sbjct 69 LERYLETFSHTVGVMQTRDALVRVAAECAEDLAEDGVVYAEVRYAPEQHLEGGLTLEEVV 128 Query 124 DTVLTGFAAGEKACAADGQPITVRCLVTAMRHAAMSREIAELAIRFRDKGVVGFDIAGAE 183 D V GF GE+ +G I V L+TAMRHAA S EIAELA R+R++GVVGFDIAGAE Sbjct 129 DAVNEGFRLGERRARENGHRIRVGALLTAMRHAARSLEIAELANRYRNQGVVGFDIAGAE 188 Query 184 AGHPPTRHLDAFEYMRDHNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDIDVD 243 AG+PPTRHLDAFEY++ N FTIHAGEAFGLPSI +A+ +CGADRLGHGVRI+DDI+V Sbjct 189 AGYPPTRHLDAFEYLKRENNHFTIHAGEAFGLPSIWQALQWCGADRLGHGVRIIDDIEVR 248 Query 244 ADGGFQLGRLAAILRDKRIPLELCPSSNVQTGAVASIAEHPFDLLARARFRVTVNTDNRL 303 DG LGRLA+ +RDKR+PLELCPSSN+QTGA AS AEHP LL R FRVTVNTDNRL Sbjct 249 DDGTVALGRLASYVRDKRVPLELCPSSNLQTGAAASYAEHPIGLLRRLHFRVTVNTDNRL 308 Query 304 MSDTSMSLEMHRLVEAFGYGWSDLARFTVNAMKSAFIPFDQRLAIIDEVIKPRFAAL 360 MS T MS E LV+AFGY D+ F+VNAMKSAFIPFD+RLA+I++VIKP +A L Sbjct 309 MSHTGMSREFEHLVDAFGYTLDDMQWFSVNAMKSAFIPFDERLAMINDVIKPGYAEL 365 >gi|291437633|ref|ZP_06577023.1| adenosine deaminase [Streptomyces ghanaensis ATCC 14672] gi|291340528|gb|EFE67484.1| adenosine deaminase [Streptomyces ghanaensis ATCC 14672] Length=385 Score = 488 bits (1257), Expect = 5e-136, Method: Compositional matrix adjust. Identities = 242/356 (68%), Positives = 276/356 (78%), Gaps = 0/356 (0%) Query 5 PTLQTIRLAPKALLHDHLDGGLRPATVLDIAGQVGYDDLPATDVDALASWFRTQSHSGSL 64 PT IR APK LLHDHLDGGLRP TV+D+A + GY LP +D D LA WF + SGSL Sbjct 10 PTTDQIRRAPKVLLHDHLDGGLRPGTVVDLARETGYTGLPESDPDKLALWFHQAADSGSL 69 Query 65 ERYLEPFSHTVAVMQTPEALYRVAFECAQDLAADSVVYAEVRFAPELHISCGLSFDDVVD 124 ERYLE FSHTV VMQT EAL RVA ECA+DLA D VVYAEVR+APE H+ GL+ ++VV+ Sbjct 70 ERYLETFSHTVGVMQTREALVRVAAECAEDLAEDGVVYAEVRYAPEQHLEGGLTLEEVVE 129 Query 125 TVLTGFAAGEKACAADGQPITVRCLVTAMRHAAMSREIAELAIRFRDKGVVGFDIAGAEA 184 V GF GE+ +G I V L+TAMRHAA S EIAELA R+RD GVVGFDIAGAEA Sbjct 130 AVNEGFRQGERRARENGHRIRVGALLTAMRHAARSLEIAELANRYRDSGVVGFDIAGAEA 189 Query 185 GHPPTRHLDAFEYMRDHNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDIDVDA 244 GHPPTRHLDAFEY++ N FTIHAGEAFGLPSI +A+ +CGADRLGHGVRI+DDI V Sbjct 190 GHPPTRHLDAFEYLKRENNHFTIHAGEAFGLPSIWQALQWCGADRLGHGVRIIDDIHVRD 249 Query 245 DGGFQLGRLAAILRDKRIPLELCPSSNVQTGAVASIAEHPFDLLARARFRVTVNTDNRLM 304 DG +LGRLA+ +RDKRIPLELCPSSN+QTGA AS AEHP LL R FRVTVNTDNRLM Sbjct 250 DGTVELGRLASYVRDKRIPLELCPSSNLQTGAAASYAEHPIGLLRRLHFRVTVNTDNRLM 309 Query 305 SDTSMSLEMHRLVEAFGYGWSDLARFTVNAMKSAFIPFDQRLAIIDEVIKPRFAAL 360 S T MS E LV+AF Y D+ F+VNAMKSAFIPFD+RLA+I++VIKP +A L Sbjct 310 SHTGMSREFEHLVDAFSYTLDDMQWFSVNAMKSAFIPFDERLAMINDVIKPGYAEL 365 >gi|145593373|ref|YP_001157670.1| adenosine deaminase [Salinispora tropica CNB-440] gi|145302710|gb|ABP53292.1| adenosine deaminase [Salinispora tropica CNB-440] Length=364 Score = 488 bits (1256), Expect = 6e-136, Method: Compositional matrix adjust. Identities = 251/361 (70%), Positives = 283/361 (79%), Gaps = 3/361 (0%) Query 1 MTAAPTLQTIRLAPKALLHDHLDGGLRPATVLDIAGQVGYDDLPATDVDALASWFRTQSH 60 M A + I APKALLHDHLDGGLRPATV+++A + G++ LP TD +AL WF + Sbjct 1 MVATIRYEDIVQAPKALLHDHLDGGLRPATVVELAAEAGHE-LPTTDPEALGRWFVDAAS 59 Query 61 SGSLERYLEPFSHTVAVMQTPEALYRVAFECAQDLAADSVVYAEVRFAPELHISCGLSFD 120 SGSLERYLE F+HTV VMQT AL RVA ECA DLAAD VVYAEVRFAPELH+ GL+ D Sbjct 60 SGSLERYLETFAHTVQVMQTASALRRVARECALDLAADGVVYAEVRFAPELHLERGLTLD 119 Query 121 DVVDTVLTGFAAGEKACAADGQPITVRCLVTAMRHAAMSREIAELAIRFRDKGVVGFDIA 180 +VV+ V+ GFA G A AA+G PI V L+TAMRHAA S+EIAELA+R RD GVVGFDIA Sbjct 120 EVVEAVIAGFAEGSTAAAAEGTPIRVGTLLTAMRHAARSQEIAELAVRHRDTGVVGFDIA 179 Query 181 GAEAGHPPTRHLDAFEYMRDHNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDI 240 GAEAG PPTRHLDAFEY++ N FTIHAGEAFGLPSI +AI +CGADRLGHGVRIVDDI Sbjct 180 GAEAGFPPTRHLDAFEYLQRENFHFTIHAGEAFGLPSIWQAIQWCGADRLGHGVRIVDDI 239 Query 241 DVDADGGFQLGRLAAILRDKRIPLELCPSSNVQTGAVASIAEHPFDLLARARFRVTVNTD 300 + LGRLAA +RDKRIPLELCPSSNVQTGA SIA+HP LL RFRVTVNTD Sbjct 240 TPGPEP--VLGRLAAYVRDKRIPLELCPSSNVQTGAAPSIADHPIGLLRDLRFRVTVNTD 297 Query 301 NRLMSDTSMSLEMHRLVEAFGYGWSDLARFTVNAMKSAFIPFDQRLAIIDEVIKPRFAAL 360 NRLMS TSMS EM LV+AFGYGW ++ T+NAMKSAFIPFDQRL IIDEVIKP + L Sbjct 298 NRLMSGTSMSREMALLVDAFGYGWREMQWLTINAMKSAFIPFDQRLQIIDEVIKPAYGRL 357 Query 361 M 361 + Sbjct 358 L 358 >gi|294631077|ref|ZP_06709637.1| adenosine deaminase [Streptomyces sp. e14] gi|292834410|gb|EFF92759.1| adenosine deaminase [Streptomyces sp. e14] Length=387 Score = 488 bits (1256), Expect = 7e-136, Method: Compositional matrix adjust. Identities = 245/356 (69%), Positives = 281/356 (79%), Gaps = 0/356 (0%) Query 5 PTLQTIRLAPKALLHDHLDGGLRPATVLDIAGQVGYDDLPATDVDALASWFRTQSHSGSL 64 P+ I APK LLHDHLDGGLRPATV+++A + GY LP T+ D L WFR + SGSL Sbjct 12 PSRDQILRAPKVLLHDHLDGGLRPATVVELARECGYSGLPDTEPDKLGLWFREAADSGSL 71 Query 65 ERYLEPFSHTVAVMQTPEALYRVAFECAQDLAADSVVYAEVRFAPELHISCGLSFDDVVD 124 ERYLE FSHTVAVMQT +AL RVA ECA+DLAAD VVYAEVR+APE H+ LS ++VV+ Sbjct 72 ERYLETFSHTVAVMQTRDALVRVARECAEDLAADGVVYAEVRYAPEQHLEGDLSLEEVVE 131 Query 125 TVLTGFAAGEKACAADGQPITVRCLVTAMRHAAMSREIAELAIRFRDKGVVGFDIAGAEA 184 V GF GE+A ADG+ I + L+TAMRHAA S EIAELA R+RD GVVGFDIAGAEA Sbjct 132 AVNEGFREGERAALADGRRIRIGALLTAMRHAARSLEIAELADRYRDSGVVGFDIAGAEA 191 Query 185 GHPPTRHLDAFEYMRDHNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDIDVDA 244 G+PPTRHLDAFE+++ N FTIHAGEAFGLPSI +A+ +CGADRLGHGVRI+DDI V Sbjct 192 GYPPTRHLDAFEFLKRANNHFTIHAGEAFGLPSIWQALQWCGADRLGHGVRIIDDITVRE 251 Query 245 DGGFQLGRLAAILRDKRIPLELCPSSNVQTGAVASIAEHPFDLLARARFRVTVNTDNRLM 304 DG +LGRLA+ +RDKRIPLELCPSSN+QTGA AS AEHP LL R FR TVNTDNRLM Sbjct 252 DGTVELGRLASYVRDKRIPLELCPSSNLQTGAAASYAEHPIGLLRRLHFRATVNTDNRLM 311 Query 305 SDTSMSLEMHRLVEAFGYGWSDLARFTVNAMKSAFIPFDQRLAIIDEVIKPRFAAL 360 S TSMS E LVEAFGY DL FTVN MKSAFIPFD+RLA+I++VIKP +AAL Sbjct 312 SHTSMSQEFEHLVEAFGYTLDDLQWFTVNGMKSAFIPFDERLAMINDVIKPGYAAL 367 >gi|336177055|ref|YP_004582430.1| adenosine deaminase [Frankia symbiont of Datisca glomerata] gi|334858035|gb|AEH08509.1| Adenosine deaminase [Frankia symbiont of Datisca glomerata] Length=361 Score = 488 bits (1256), Expect = 7e-136, Method: Compositional matrix adjust. Identities = 240/358 (68%), Positives = 280/358 (79%), Gaps = 5/358 (1%) Query 5 PTLQTIRLAPKALLHDHLDGGLRPATVLDIAGQVGYDDLPATDVDALASWFRTQSHSGSL 64 PTL+ IR PK LLHDHLDGGLRPATV+++A +VGY LP TD D LA+WFR +HSGSL Sbjct 7 PTLEAIRRVPKVLLHDHLDGGLRPATVVELADEVGYGGLPTTDADKLATWFRGGAHSGSL 66 Query 65 ERYLEPFSHTVAVMQTPEALYRVAFECAQDLAADSVVYAEVRFAPELHISCGLSFDDVVD 124 RYLE FSHTV VMQTP AL RVA ECA+DLAAD VVYAEVRFAPELH+ GL+ D V++ Sbjct 67 VRYLETFSHTVGVMQTPGALARVARECAEDLAADGVVYAEVRFAPELHVERGLALDAVIE 126 Query 125 TVLTGFAAGEKACAADGQPITVRCLVTAMRHAAMSREIAELAIRFRDKGVVGFDIAGAEA 184 V+ GF AG G + +R L+TAMRHAA S EIAE A+R+RD+GVVGFDIAGAEA Sbjct 127 AVIDGFRAGSA-----GTGLKIRALLTAMRHAARSLEIAEAAVRWRDRGVVGFDIAGAEA 181 Query 185 GHPPTRHLDAFEYMRDHNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDIDVDA 244 G+PPTRHLDAF+YM+ N +TIHAGEAFGLPSI EA+ +C ADRLGHGVR+ DDI VD Sbjct 182 GYPPTRHLDAFQYMQRANGHYTIHAGEAFGLPSIWEALQWCNADRLGHGVRVTDDITVDT 241 Query 245 DGGFQLGRLAAILRDKRIPLELCPSSNVQTGAVASIAEHPFDLLARARFRVTVNTDNRLM 304 D LG+LA +RD R+PLE+CP+SNV TG ASIAEHP LL R FRVTVNTDNRLM Sbjct 242 DANAILGQLANYVRDVRVPLEMCPTSNVDTGVCASIAEHPIGLLRRLHFRVTVNTDNRLM 301 Query 305 SDTSMSLEMHRLVEAFGYGWSDLARFTVNAMKSAFIPFDQRLAIIDEVIKPRFAALMG 362 S ++S E LV+AFGYGW D+ TVNAMKSAFIPFDQRL +I++VIKP FA++ G Sbjct 302 SGVTLSSEFAALVDAFGYGWPDIRWLTVNAMKSAFIPFDQRLTLINDVIKPGFASVCG 359 >gi|291298884|ref|YP_003510162.1| adenosine deaminase [Stackebrandtia nassauensis DSM 44728] gi|290568104|gb|ADD41069.1| adenosine deaminase [Stackebrandtia nassauensis DSM 44728] Length=360 Score = 486 bits (1252), Expect = 2e-135, Method: Compositional matrix adjust. Identities = 242/357 (68%), Positives = 284/357 (80%), Gaps = 1/357 (0%) Query 6 TLQTIRLAPKALLHDHLDGGLRPATVLDIAGQVGYDDLPATDVDALASWFRTQSHSGSLE 65 +++ IR APKALLHDHLDGGLRPATV+++A +G++ LP TDV AL WF ++SGSLE Sbjct 4 SIEEIRQAPKALLHDHLDGGLRPATVIELAEGIGHE-LPTTDVTALGQWFVDAANSGSLE 62 Query 66 RYLEPFSHTVAVMQTPEALYRVAFECAQDLAADSVVYAEVRFAPELHISCGLSFDDVVDT 125 RYLE F+HTVAVMQT E+L+RVA+ECA+DLA D VVYAEVRFAPELH L D+VV++ Sbjct 63 RYLETFAHTVAVMQTAESLHRVAYECARDLADDGVVYAEVRFAPELHTEAELGLDEVVES 122 Query 126 VLTGFAAGEKACAADGQPITVRCLVTAMRHAAMSREIAELAIRFRDKGVVGFDIAGAEAG 185 VL GFAAG A +G I V L+TAMRHAA S EIAELA+R+RD GVVGFDIAGAEAG Sbjct 123 VLAGFAAGCADAAREGHQIRVGALLTAMRHAARSMEIAELAVRYRDSGVVGFDIAGAEAG 182 Query 186 HPPTRHLDAFEYMRDHNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDIDVDAD 245 PPTRHLDAFEY++ N+RFTIHAGE FGLPSI +A+ +CGA RLGHGVRIVDDI D Sbjct 183 FPPTRHLDAFEYLQRENSRFTIHAGEGFGLPSIWQALQWCGAHRLGHGVRIVDDISFGDD 242 Query 246 GGFQLGRLAAILRDKRIPLELCPSSNVQTGAVASIAEHPFDLLARARFRVTVNTDNRLMS 305 LGRLA +RD R+PLELCPSSN+QTGA SI EHP LL + RFRVTVNTDNRLMS Sbjct 243 ATPTLGRLAHYVRDTRVPLELCPSSNLQTGAADSITEHPIGLLTKLRFRVTVNTDNRLMS 302 Query 306 DTSMSLEMHRLVEAFGYGWSDLARFTVNAMKSAFIPFDQRLAIIDEVIKPRFAALMG 362 TS+S EM L +AFGYGW +L FT+NAMKS+FI FD+RLAIID+VIKP + L+G Sbjct 303 GTSLSREMALLSDAFGYGWPELRWFTINAMKSSFIRFDERLAIIDDVIKPAYTKLIG 359 >gi|29829900|ref|NP_824534.1| adenosine deaminase [Streptomyces avermitilis MA-4680] gi|29607009|dbj|BAC71069.1| putative adenosine deaminase [Streptomyces avermitilis MA-4680] Length=404 Score = 486 bits (1252), Expect = 2e-135, Method: Compositional matrix adjust. Identities = 240/356 (68%), Positives = 278/356 (79%), Gaps = 0/356 (0%) Query 5 PTLQTIRLAPKALLHDHLDGGLRPATVLDIAGQVGYDDLPATDVDALASWFRTQSHSGSL 64 P+ + IR APK LLHDHLDGGLRP T++++A GY LP TD D L WFR + SGSL Sbjct 29 PSSEQIRRAPKVLLHDHLDGGLRPGTIVELARDAGYSGLPETDPDKLGIWFREAADSGSL 88 Query 65 ERYLEPFSHTVAVMQTPEALYRVAFECAQDLAADSVVYAEVRFAPELHISCGLSFDDVVD 124 ERYLE F+HT AVMQT AL RVA ECA+DLAAD VVYAEVR+APE H+ GLS ++VV+ Sbjct 89 ERYLETFAHTCAVMQTRAALVRVAAECAEDLAADGVVYAEVRYAPEQHLEAGLSLEEVVE 148 Query 125 TVLTGFAAGEKACAADGQPITVRCLVTAMRHAAMSREIAELAIRFRDKGVVGFDIAGAEA 184 V GF AGE+ DG I V L+TAMRHAA + EIAELA R+RD GVVGFDIAGAEA Sbjct 149 AVNEGFRAGERRAKEDGNRIRVGALLTAMRHAARALEIAELANRYRDAGVVGFDIAGAEA 208 Query 185 GHPPTRHLDAFEYMRDHNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDIDVDA 244 G PPTRHLDAFEY++ N FTIHAGEAFGLPSI +A+ +CGADRLGHGVRI+DDI V Sbjct 209 GFPPTRHLDAFEYLKRENNHFTIHAGEAFGLPSIWQALQWCGADRLGHGVRIIDDIQVRE 268 Query 245 DGGFQLGRLAAILRDKRIPLELCPSSNVQTGAVASIAEHPFDLLARARFRVTVNTDNRLM 304 DG +LGRLA+ +RDKRIPLELCPSSN+QTGA +S A+HP LL R FR TVNTDNRLM Sbjct 269 DGSVKLGRLASYVRDKRIPLELCPSSNLQTGAASSYADHPIGLLRRLHFRATVNTDNRLM 328 Query 305 SDTSMSLEMHRLVEAFGYGWSDLARFTVNAMKSAFIPFDQRLAIIDEVIKPRFAAL 360 S TSMS E LV+AFGY D+A F+VNAMKSAFIPFD+RLA+I++VIKP +A L Sbjct 329 SGTSMSREFEHLVDAFGYTLDDMAWFSVNAMKSAFIPFDERLAMINDVIKPGYAEL 384 >gi|254389917|ref|ZP_05005140.1| adenosine deaminase [Streptomyces clavuligerus ATCC 27064] gi|294814637|ref|ZP_06773280.1| Adenosine deaminase [Streptomyces clavuligerus ATCC 27064] gi|197703627|gb|EDY49439.1| adenosine deaminase [Streptomyces clavuligerus ATCC 27064] gi|294327236|gb|EFG08879.1| Adenosine deaminase [Streptomyces clavuligerus ATCC 27064] Length=382 Score = 486 bits (1252), Expect = 2e-135, Method: Compositional matrix adjust. Identities = 241/356 (68%), Positives = 278/356 (79%), Gaps = 0/356 (0%) Query 5 PTLQTIRLAPKALLHDHLDGGLRPATVLDIAGQVGYDDLPATDVDALASWFRTQSHSGSL 64 PT + IR APK LLHDHLDGGLRP TV+D+A GY+ LP T+ D L +WFR + SGSL Sbjct 9 PTAEQIRRAPKVLLHDHLDGGLRPGTVVDLARDAGYEALPETEPDRLGAWFREAADSGSL 68 Query 65 ERYLEPFSHTVAVMQTPEALYRVAFECAQDLAADSVVYAEVRFAPELHISCGLSFDDVVD 124 ERYLE F+HT AV QT +AL+RVA ECA+DLAAD VVYAEVR+APE H+ GL ++VV Sbjct 69 ERYLETFAHTCAVTQTADALFRVAAECAEDLAADGVVYAEVRYAPEQHLEGGLGLEEVVA 128 Query 125 TVLTGFAAGEKACAADGQPITVRCLVTAMRHAAMSREIAELAIRFRDKGVVGFDIAGAEA 184 V GF GE+ +G+ I V L+TAMRHAA S EIAELA R RD GVVGFDIAGAEA Sbjct 129 AVNEGFREGERLARENGRRIRVGALLTAMRHAARSLEIAELANRHRDTGVVGFDIAGAEA 188 Query 185 GHPPTRHLDAFEYMRDHNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDIDVDA 244 GHPPTRHLDAFEY++ N FTIHAGEAFGLPSI +A+ +CGADRLGHGVRIVDDI V A Sbjct 189 GHPPTRHLDAFEYLKRENNHFTIHAGEAFGLPSIWQALQWCGADRLGHGVRIVDDITVGA 248 Query 245 DGGFQLGRLAAILRDKRIPLELCPSSNVQTGAVASIAEHPFDLLARARFRVTVNTDNRLM 304 DG LGRLAA +RD+R+PLELCP+SN+QTGAV S A+HP LL R FR TVNTDNRLM Sbjct 249 DGEVTLGRLAAYVRDRRVPLELCPTSNLQTGAVGSYADHPIGLLRRLHFRATVNTDNRLM 308 Query 305 SDTSMSLEMHRLVEAFGYGWSDLARFTVNAMKSAFIPFDQRLAIIDEVIKPRFAAL 360 S TS+S E RL EAFGY D+ FTVNAMKSAFIPFD+RLA+I++VIKP F+ L Sbjct 309 SGTSVSQEFERLTEAFGYSLDDIQWFTVNAMKSAFIPFDERLAMINDVIKPGFSEL 364 >gi|302536426|ref|ZP_07288768.1| adenosine deaminase [Streptomyces sp. C] gi|302445321|gb|EFL17137.1| adenosine deaminase [Streptomyces sp. C] Length=382 Score = 486 bits (1251), Expect = 3e-135, Method: Compositional matrix adjust. Identities = 234/356 (66%), Positives = 279/356 (79%), Gaps = 0/356 (0%) Query 5 PTLQTIRLAPKALLHDHLDGGLRPATVLDIAGQVGYDDLPATDVDALASWFRTQSHSGSL 64 PT IR +PK LLHDHLDGGLRP T++++A +VGYD LP TD D L WFR + SGSL Sbjct 9 PTPDQIRRSPKVLLHDHLDGGLRPGTIIELAAEVGYDKLPETDADKLGVWFRDAADSGSL 68 Query 65 ERYLEPFSHTVAVMQTPEALYRVAFECAQDLAADSVVYAEVRFAPELHISCGLSFDDVVD 124 RYLE F+HT AVMQT EAL+RVA ECA+DLA D VVYAE+R+APE H+ GL+ ++VV+ Sbjct 69 PRYLETFAHTCAVMQTKEALFRVAAECAEDLAEDGVVYAEIRYAPEQHLEAGLTLEEVVE 128 Query 125 TVLTGFAAGEKACAADGQPITVRCLVTAMRHAAMSREIAELAIRFRDKGVVGFDIAGAEA 184 V GF GE+ A+G I V L+TAMRHAA + EIAELA R+RD GVVGFDIAGAEA Sbjct 129 AVNDGFREGERRARANGHRIRVGALLTAMRHAARALEIAELANRYRDNGVVGFDIAGAEA 188 Query 185 GHPPTRHLDAFEYMRDHNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDIDVDA 244 G PPTRHLDAFEY++ N FTIHAGEAFGLPSI +A+ +CGADRLGHGV+I+DDI+V Sbjct 189 GFPPTRHLDAFEYLKRENNHFTIHAGEAFGLPSIWQALQWCGADRLGHGVKIIDDIEVAE 248 Query 245 DGGFQLGRLAAILRDKRIPLELCPSSNVQTGAVASIAEHPFDLLARARFRVTVNTDNRLM 304 DG +LGRLA+ +RDKRIPLE+CP+SN+QT A AS AEHP LL + FR+TVNTDNRLM Sbjct 249 DGSVKLGRLASYVRDKRIPLEMCPTSNLQTAAAASYAEHPIGLLRKLHFRLTVNTDNRLM 308 Query 305 SDTSMSLEMHRLVEAFGYGWSDLARFTVNAMKSAFIPFDQRLAIIDEVIKPRFAAL 360 S TSMS E LV+ FGY D+ FTVNAMKSAFIPFD+RLA+I++VIKP +A L Sbjct 309 SGTSMSREFEHLVDTFGYSLDDMQWFTVNAMKSAFIPFDERLAMINDVIKPGYAEL 364 Lambda K H 0.324 0.137 0.410 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 688239003200 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40