BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv3314c Length=427 Score E Sequences producing significant alignments: (Bits) Value gi|15610450|ref|NP_217831.1| thymidine phosphorylase [Mycobacter... 843 0.0 gi|340628298|ref|YP_004746750.1| putative thymidine phosphorylas... 841 0.0 gi|306786189|ref|ZP_07424511.1| thymidine phosphorylase deoA [My... 841 0.0 gi|31794495|ref|NP_856988.1| thymidine phosphorylase [Mycobacter... 839 0.0 gi|339633322|ref|YP_004724964.1| thymidine phosphorylase DEOA (T... 837 0.0 gi|118617050|ref|YP_905382.1| thymidine phosphorylase [Mycobacte... 734 0.0 gi|183981227|ref|YP_001849518.1| thymidine phosphorylase DeoA [M... 734 0.0 gi|240169121|ref|ZP_04747780.1| thymidine phosphorylase [Mycobac... 724 0.0 gi|342861540|ref|ZP_08718187.1| thymidine phosphorylase [Mycobac... 701 0.0 gi|254820238|ref|ZP_05225239.1| thymidine phosphorylase [Mycobac... 693 0.0 gi|254776728|ref|ZP_05218244.1| thymidine phosphorylase [Mycobac... 677 0.0 gi|41409537|ref|NP_962373.1| thymidine phosphorylase [Mycobacter... 674 0.0 gi|336459595|gb|EGO38530.1| pyrimidine-nucleoside phosphorylase ... 674 0.0 gi|118467210|ref|YP_883433.1| thymidine phosphorylase [Mycobacte... 673 0.0 gi|296168863|ref|ZP_06850535.1| pyrimidine-nucleoside phosphoryl... 673 0.0 gi|120402597|ref|YP_952426.1| thymidine phosphorylase [Mycobacte... 634 1e-179 gi|126433860|ref|YP_001069551.1| thymidine phosphorylase [Mycoba... 625 4e-177 gi|108798203|ref|YP_638400.1| thymidine phosphorylase [Mycobacte... 618 5e-175 gi|145225420|ref|YP_001136098.1| thymidine phosphorylase [Mycoba... 615 5e-174 gi|118470133|ref|YP_886051.1| thymidine phosphorylase [Mycobacte... 589 3e-166 gi|333991781|ref|YP_004524395.1| thymidine phosphorylase DeoA [M... 552 4e-155 gi|169630750|ref|YP_001704399.1| thymidine phosphorylase [Mycoba... 533 3e-149 gi|226365718|ref|YP_002783501.1| thymidine phosphorylase [Rhodoc... 524 1e-146 gi|111023213|ref|YP_706185.1| thymidine phosphorylase [Rhodococc... 521 9e-146 gi|229489381|ref|ZP_04383244.1| pyrimidine-nucleoside phosphoryl... 520 2e-145 gi|226305534|ref|YP_002765494.1| pyrimidine nucleoside phosphory... 520 2e-145 gi|337767771|emb|CCB76482.1| Thymidine phosphorylase [Streptomyc... 518 9e-145 gi|297158060|gb|ADI07772.1| thymidine phosphorylase [Streptomyce... 513 3e-143 gi|345015794|ref|YP_004818148.1| pyrimidine-nucleoside phosphory... 511 7e-143 gi|326334079|ref|ZP_08200307.1| thymidine phosphorylase [Nocardi... 510 1e-142 gi|291437641|ref|ZP_06577031.1| thymidine phosphorylase [Strepto... 508 5e-142 gi|290957952|ref|YP_003489134.1| thymidine phosphorylase [Strept... 508 7e-142 gi|302544708|ref|ZP_07297050.1| pyrimidine-nucleoside phosphoryl... 506 2e-141 gi|318060158|ref|ZP_07978881.1| thymidine phosphorylase [Strepto... 505 5e-141 gi|297562172|ref|YP_003681146.1| pyrimidine-nucleoside phosphory... 505 6e-141 gi|302519472|ref|ZP_07271814.1| thymidine phosphorylase [Strepto... 505 7e-141 gi|291451662|ref|ZP_06591052.1| thymidine phosphorylase [Strepto... 504 1e-140 gi|333026699|ref|ZP_08454763.1| putative thymidine phosphorylase... 503 2e-140 gi|329935626|ref|ZP_08285433.1| thymidine phosphorylase [Strepto... 503 3e-140 gi|294631070|ref|ZP_06709630.1| thymidine phosphorylase [Strepto... 503 4e-140 gi|54022918|ref|YP_117160.1| thymidine phosphorylase [Nocardia f... 501 1e-139 gi|297192493|ref|ZP_06909891.1| thymidine phosphorylase [Strepto... 501 1e-139 gi|295838601|ref|ZP_06825534.1| thymidine phosphorylase [Strepto... 500 2e-139 gi|21223264|ref|NP_629043.1| thymidine phosphorylase [Streptomyc... 499 5e-139 gi|334336495|ref|YP_004541647.1| pyrimidine-nucleoside phosphory... 499 5e-139 gi|302536416|ref|ZP_07288758.1| thymidine phosphorylase [Strepto... 498 6e-139 gi|29829907|ref|NP_824541.1| thymidine phosphorylase [Streptomyc... 498 1e-138 gi|302558816|ref|ZP_07311158.1| thymidine phosphorylase [Strepto... 497 1e-138 gi|302553742|ref|ZP_07306084.1| thymidine phosphorylase [Strepto... 496 3e-138 gi|116669703|ref|YP_830636.1| thymidine phosphorylase [Arthrobac... 496 3e-138 >gi|15610450|ref|NP_217831.1| thymidine phosphorylase [Mycobacterium tuberculosis H37Rv] gi|15842906|ref|NP_337943.1| thymidine phosphorylase [Mycobacterium tuberculosis CDC1551] gi|148663178|ref|YP_001284701.1| thymidine phosphorylase [Mycobacterium tuberculosis H37Ra] 61 more sequence titles Length=427 Score = 843 bits (2178), Expect = 0.0, Method: Compositional matrix adjust. Identities = 426/427 (99%), Positives = 427/427 (100%), Gaps = 0/427 (0%) Query 1 VTDFAFDAPTVIRTKRDGGRLSDAAIDWVVKAYTDGRVADEQMSALLMAIVWRGMDRGEI 60 +TDFAFDAPTVIRTKRDGGRLSDAAIDWVVKAYTDGRVADEQMSALLMAIVWRGMDRGEI Sbjct 1 MTDFAFDAPTVIRTKRDGGRLSDAAIDWVVKAYTDGRVADEQMSALLMAIVWRGMDRGEI 60 Query 61 ARWTAAMLASGARLDFTDLPLATVDKHSTGGVGDKITLPLVPVVAACGGAVPQASGRGLG 120 ARWTAAMLASGARLDFTDLPLATVDKHSTGGVGDKITLPLVPVVAACGGAVPQASGRGLG Sbjct 61 ARWTAAMLASGARLDFTDLPLATVDKHSTGGVGDKITLPLVPVVAACGGAVPQASGRGLG 120 Query 121 HTGGTLDKLESITGFTANLSNQRVREQLCDVGAAIFAAGQLAPADAKLYALRDITGTVES 180 HTGGTLDKLESITGFTANLSNQRVREQLCDVGAAIFAAGQLAPADAKLYALRDITGTVES Sbjct 121 HTGGTLDKLESITGFTANLSNQRVREQLCDVGAAIFAAGQLAPADAKLYALRDITGTVES 180 Query 181 LPLIASSIMSKKLAEGAGALVLDVKVGSGAFMRSPVQARELAHTMVELGAAHGVPTRALL 240 LPLIASSIMSKKLAEGAGALVLDVKVGSGAFMRSPVQARELAHTMVELGAAHGVPTRALL Sbjct 181 LPLIASSIMSKKLAEGAGALVLDVKVGSGAFMRSPVQARELAHTMVELGAAHGVPTRALL 240 Query 241 TEMNCPLGRTVGNALEVAEALEVLAGGGPPDVVELTLRLAGEMLELAGIHGRDPAQTLRD 300 TEMNCPLGRTVGNALEVAEALEVLAGGGPPDVVELTLRLAGEMLELAGIHGRDPAQTLRD Sbjct 241 TEMNCPLGRTVGNALEVAEALEVLAGGGPPDVVELTLRLAGEMLELAGIHGRDPAQTLRD 300 Query 301 GTAMDRFRRLVAAQGGDLSKPLPIGSHSETVTAGASGTMGDIDAMAVGLAAWRLGAGRSR 360 GTAMDRFRRLVAAQGGDLSKPLPIGSHSETVTAGASGTMGDIDAMAVGLAAWRLGAGRSR Sbjct 301 GTAMDRFRRLVAAQGGDLSKPLPIGSHSETVTAGASGTMGDIDAMAVGLAAWRLGAGRSR 360 Query 361 PGARVQHGAGVRIHRRPGEPVVVGEPLFTLYTNAPERFGAARAELAGGWSIRDSPPQVRP 420 PGARVQHGAGVRIHRRPGEPVVVGEPLFTLYTNAPERFGAARAELAGGWSIRDSPPQVRP Sbjct 361 PGARVQHGAGVRIHRRPGEPVVVGEPLFTLYTNAPERFGAARAELAGGWSIRDSPPQVRP 420 Query 421 LIVDRIV 427 LIVDRIV Sbjct 421 LIVDRIV 427 >gi|340628298|ref|YP_004746750.1| putative thymidine phosphorylase DEOA [Mycobacterium canettii CIPT 140010059] gi|340006488|emb|CCC45671.1| putative thymidine phosphorylase DEOA (TDRPASE) (pyrimidine phosphorylase) [Mycobacterium canettii CIPT 140010059] Length=427 Score = 841 bits (2173), Expect = 0.0, Method: Compositional matrix adjust. Identities = 425/427 (99%), Positives = 427/427 (100%), Gaps = 0/427 (0%) Query 1 VTDFAFDAPTVIRTKRDGGRLSDAAIDWVVKAYTDGRVADEQMSALLMAIVWRGMDRGEI 60 +TDFAFDAPTVIRTKRDGGRLSDAAIDWVVKAYTDGRVADEQMSALLMAIVWRGMDRGEI Sbjct 1 MTDFAFDAPTVIRTKRDGGRLSDAAIDWVVKAYTDGRVADEQMSALLMAIVWRGMDRGEI 60 Query 61 ARWTAAMLASGARLDFTDLPLATVDKHSTGGVGDKITLPLVPVVAACGGAVPQASGRGLG 120 ARWTAAMLASGARLDFTDLPLATVDKHSTGGVGDKITLPLVPVVAACGGAVPQASGRGLG Sbjct 61 ARWTAAMLASGARLDFTDLPLATVDKHSTGGVGDKITLPLVPVVAACGGAVPQASGRGLG 120 Query 121 HTGGTLDKLESITGFTANLSNQRVREQLCDVGAAIFAAGQLAPADAKLYALRDITGTVES 180 HTGGTLDKLESITGFTANLSNQRVREQLCDVGAAIFAAGQLAPADAKLYALRDITGTVES Sbjct 121 HTGGTLDKLESITGFTANLSNQRVREQLCDVGAAIFAAGQLAPADAKLYALRDITGTVES 180 Query 181 LPLIASSIMSKKLAEGAGALVLDVKVGSGAFMRSPVQARELAHTMVELGAAHGVPTRALL 240 LPLIASSIMSKKLAEGAGALVLDVKVGSGAFMRSPVQARELAHTMVELGAAHGVPTRALL Sbjct 181 LPLIASSIMSKKLAEGAGALVLDVKVGSGAFMRSPVQARELAHTMVELGAAHGVPTRALL 240 Query 241 TEMNCPLGRTVGNALEVAEALEVLAGGGPPDVVELTLRLAGEMLELAGIHGRDPAQTLRD 300 TEMNCPLGRTVGNALEVAEALEVLAGGGPPDVVELTLRLAGEMLELAGIHGRDPAQTLRD Sbjct 241 TEMNCPLGRTVGNALEVAEALEVLAGGGPPDVVELTLRLAGEMLELAGIHGRDPAQTLRD 300 Query 301 GTAMDRFRRLVAAQGGDLSKPLPIGSHSETVTAGASGTMGDIDAMAVGLAAWRLGAGRSR 360 GTAMDRFRRLVAAQGGDLSKPLPIGSHSETVTAGASGTMGDIDAMAVGLAAWRLGAGRSR Sbjct 301 GTAMDRFRRLVAAQGGDLSKPLPIGSHSETVTAGASGTMGDIDAMAVGLAAWRLGAGRSR 360 Query 361 PGARVQHGAGVRIHRRPGEPVVVGEPLFTLYTNAPERFGAARAELAGGWSIRDSPPQVRP 420 PGARVQHGAGVRIHRRPGEPVVVGEPLFTLYTNAPERFGAARAELAGGWSIRDSPP+VRP Sbjct 361 PGARVQHGAGVRIHRRPGEPVVVGEPLFTLYTNAPERFGAARAELAGGWSIRDSPPRVRP 420 Query 421 LIVDRIV 427 LIVDRIV Sbjct 421 LIVDRIV 427 >gi|306786189|ref|ZP_07424511.1| thymidine phosphorylase deoA [Mycobacterium tuberculosis SUMu003] gi|306799275|ref|ZP_07437577.1| thymidine phosphorylase deoA [Mycobacterium tuberculosis SUMu006] gi|306805124|ref|ZP_07441792.1| thymidine phosphorylase deoA [Mycobacterium tuberculosis SUMu008] gi|308329337|gb|EFP18188.1| thymidine phosphorylase deoA [Mycobacterium tuberculosis SUMu003] gi|308340688|gb|EFP29539.1| thymidine phosphorylase deoA [Mycobacterium tuberculosis SUMu006] gi|308348426|gb|EFP37277.1| thymidine phosphorylase deoA [Mycobacterium tuberculosis SUMu008] Length=427 Score = 841 bits (2173), Expect = 0.0, Method: Compositional matrix adjust. Identities = 425/427 (99%), Positives = 426/427 (99%), Gaps = 0/427 (0%) Query 1 VTDFAFDAPTVIRTKRDGGRLSDAAIDWVVKAYTDGRVADEQMSALLMAIVWRGMDRGEI 60 +TDF FDAPTVIRTKRDGGRLSDAAIDWVVKAYTDGRVADEQMSALLMAIVWRGMDRGEI Sbjct 1 MTDFVFDAPTVIRTKRDGGRLSDAAIDWVVKAYTDGRVADEQMSALLMAIVWRGMDRGEI 60 Query 61 ARWTAAMLASGARLDFTDLPLATVDKHSTGGVGDKITLPLVPVVAACGGAVPQASGRGLG 120 ARWTAAMLASGARLDFTDLPLATVDKHSTGGVGDKITLPLVPVVAACGGAVPQASGRGLG Sbjct 61 ARWTAAMLASGARLDFTDLPLATVDKHSTGGVGDKITLPLVPVVAACGGAVPQASGRGLG 120 Query 121 HTGGTLDKLESITGFTANLSNQRVREQLCDVGAAIFAAGQLAPADAKLYALRDITGTVES 180 HTGGTLDKLESITGFTANLSNQRVREQLCDVGAAIFAAGQLAPADAKLYALRDITGTVES Sbjct 121 HTGGTLDKLESITGFTANLSNQRVREQLCDVGAAIFAAGQLAPADAKLYALRDITGTVES 180 Query 181 LPLIASSIMSKKLAEGAGALVLDVKVGSGAFMRSPVQARELAHTMVELGAAHGVPTRALL 240 LPLIASSIMSKKLAEGAGALVLDVKVGSGAFMRSPVQARELAHTMVELGAAHGVPTRALL Sbjct 181 LPLIASSIMSKKLAEGAGALVLDVKVGSGAFMRSPVQARELAHTMVELGAAHGVPTRALL 240 Query 241 TEMNCPLGRTVGNALEVAEALEVLAGGGPPDVVELTLRLAGEMLELAGIHGRDPAQTLRD 300 TEMNCPLGRTVGNALEVAEALEVLAGGGPPDVVELTLRLAGEMLELAGIHGRDPAQTLRD Sbjct 241 TEMNCPLGRTVGNALEVAEALEVLAGGGPPDVVELTLRLAGEMLELAGIHGRDPAQTLRD 300 Query 301 GTAMDRFRRLVAAQGGDLSKPLPIGSHSETVTAGASGTMGDIDAMAVGLAAWRLGAGRSR 360 GTAMDRFRRLVAAQGGDLSKPLPIGSHSETVTAGASGTMGDIDAMAVGLAAWRLGAGRSR Sbjct 301 GTAMDRFRRLVAAQGGDLSKPLPIGSHSETVTAGASGTMGDIDAMAVGLAAWRLGAGRSR 360 Query 361 PGARVQHGAGVRIHRRPGEPVVVGEPLFTLYTNAPERFGAARAELAGGWSIRDSPPQVRP 420 PGARVQHGAGVRIHRRPGEPVVVGEPLFTLYTNAPERFGAARAELAGGWSIRDSPPQVRP Sbjct 361 PGARVQHGAGVRIHRRPGEPVVVGEPLFTLYTNAPERFGAARAELAGGWSIRDSPPQVRP 420 Query 421 LIVDRIV 427 LIVDRIV Sbjct 421 LIVDRIV 427 >gi|31794495|ref|NP_856988.1| thymidine phosphorylase [Mycobacterium bovis AF2122/97] gi|121639238|ref|YP_979462.1| thymidine phosphorylase [Mycobacterium bovis BCG str. Pasteur 1173P2] gi|224991697|ref|YP_002646386.1| thymidine phosphorylase [Mycobacterium bovis BCG str. Tokyo 172] 10 more sequence titles Length=427 Score = 839 bits (2167), Expect = 0.0, Method: Compositional matrix adjust. Identities = 425/427 (99%), Positives = 426/427 (99%), Gaps = 0/427 (0%) Query 1 VTDFAFDAPTVIRTKRDGGRLSDAAIDWVVKAYTDGRVADEQMSALLMAIVWRGMDRGEI 60 +TDFAFDAPTVIRTKRDGGRLSDAAIDWVVKAYTDGRVADEQMSALLMAIVWRGMDRGEI Sbjct 1 MTDFAFDAPTVIRTKRDGGRLSDAAIDWVVKAYTDGRVADEQMSALLMAIVWRGMDRGEI 60 Query 61 ARWTAAMLASGARLDFTDLPLATVDKHSTGGVGDKITLPLVPVVAACGGAVPQASGRGLG 120 ARWTAAMLASGARLDFTDLPLATVDKHSTGGVGDKITLPLVPVVAACGGAVPQASGRGLG Sbjct 61 ARWTAAMLASGARLDFTDLPLATVDKHSTGGVGDKITLPLVPVVAACGGAVPQASGRGLG 120 Query 121 HTGGTLDKLESITGFTANLSNQRVREQLCDVGAAIFAAGQLAPADAKLYALRDITGTVES 180 HTGGTLDKLESITGFTANLSNQRVREQLCDVGAAIFAAGQLAPADAKLYALRDITGTVES Sbjct 121 HTGGTLDKLESITGFTANLSNQRVREQLCDVGAAIFAAGQLAPADAKLYALRDITGTVES 180 Query 181 LPLIASSIMSKKLAEGAGALVLDVKVGSGAFMRSPVQARELAHTMVELGAAHGVPTRALL 240 LPLIASSIMSKKLAEGAGALVLDVKVGSGAFMRSPVQARELAHTMVELGAAHGVPTRALL Sbjct 181 LPLIASSIMSKKLAEGAGALVLDVKVGSGAFMRSPVQARELAHTMVELGAAHGVPTRALL 240 Query 241 TEMNCPLGRTVGNALEVAEALEVLAGGGPPDVVELTLRLAGEMLELAGIHGRDPAQTLRD 300 TEMNCPLGRTVGNALEVAEALEVLAGGGPPDVVELTLRLAGEMLELAGIHGRDPAQTLRD Sbjct 241 TEMNCPLGRTVGNALEVAEALEVLAGGGPPDVVELTLRLAGEMLELAGIHGRDPAQTLRD 300 Query 301 GTAMDRFRRLVAAQGGDLSKPLPIGSHSETVTAGASGTMGDIDAMAVGLAAWRLGAGRSR 360 GTAMDRFR LVAAQGGDLSKPLPIGSHSETVTAGASGTMGDIDAMAVGLAAWRLGAGRSR Sbjct 301 GTAMDRFRWLVAAQGGDLSKPLPIGSHSETVTAGASGTMGDIDAMAVGLAAWRLGAGRSR 360 Query 361 PGARVQHGAGVRIHRRPGEPVVVGEPLFTLYTNAPERFGAARAELAGGWSIRDSPPQVRP 420 PGARVQHGAGVRIHRRPGEPVVVGEPLFTLYTNAPERFGAARAELAGGWSIRDSPPQVRP Sbjct 361 PGARVQHGAGVRIHRRPGEPVVVGEPLFTLYTNAPERFGAARAELAGGWSIRDSPPQVRP 420 Query 421 LIVDRIV 427 LIVDRIV Sbjct 421 LIVDRIV 427 >gi|339633322|ref|YP_004724964.1| thymidine phosphorylase DEOA (TDRPASE) (pyrimidine phosphorylase) [Mycobacterium africanum GM041182] gi|339332678|emb|CCC28396.1| putative thymidine phosphorylase DEOA (TDRPASE) (pyrimidine phosphorylase) [Mycobacterium africanum GM041182] Length=427 Score = 837 bits (2163), Expect = 0.0, Method: Compositional matrix adjust. Identities = 424/427 (99%), Positives = 425/427 (99%), Gaps = 0/427 (0%) Query 1 VTDFAFDAPTVIRTKRDGGRLSDAAIDWVVKAYTDGRVADEQMSALLMAIVWRGMDRGEI 60 +TDFAFDAPTVIRTKRDGGRLSDAAIDWVVKAYTDGRV DEQMSALLMAIVWRGMDRGEI Sbjct 1 MTDFAFDAPTVIRTKRDGGRLSDAAIDWVVKAYTDGRVTDEQMSALLMAIVWRGMDRGEI 60 Query 61 ARWTAAMLASGARLDFTDLPLATVDKHSTGGVGDKITLPLVPVVAACGGAVPQASGRGLG 120 ARWTAAMLASGARLDFTDLPLATVDKHSTGGVGDKITLPLVPVVAACGGAVPQASGRGLG Sbjct 61 ARWTAAMLASGARLDFTDLPLATVDKHSTGGVGDKITLPLVPVVAACGGAVPQASGRGLG 120 Query 121 HTGGTLDKLESITGFTANLSNQRVREQLCDVGAAIFAAGQLAPADAKLYALRDITGTVES 180 HTGGTLDKLESITGFTANLSNQRVREQLCDVGAAIFAAGQLAPADAKLYALRDITGTVES Sbjct 121 HTGGTLDKLESITGFTANLSNQRVREQLCDVGAAIFAAGQLAPADAKLYALRDITGTVES 180 Query 181 LPLIASSIMSKKLAEGAGALVLDVKVGSGAFMRSPVQARELAHTMVELGAAHGVPTRALL 240 LPLIASSIMSKKLAEGAGALVLDVKVGSGAFMRSPVQARELAHTMVELGAAHGVPTRALL Sbjct 181 LPLIASSIMSKKLAEGAGALVLDVKVGSGAFMRSPVQARELAHTMVELGAAHGVPTRALL 240 Query 241 TEMNCPLGRTVGNALEVAEALEVLAGGGPPDVVELTLRLAGEMLELAGIHGRDPAQTLRD 300 TEMNCPLGRTVGNALEVAEALEVLAGGGPPDVVELTLRLAGEMLELAGIHGRDPAQTLRD Sbjct 241 TEMNCPLGRTVGNALEVAEALEVLAGGGPPDVVELTLRLAGEMLELAGIHGRDPAQTLRD 300 Query 301 GTAMDRFRRLVAAQGGDLSKPLPIGSHSETVTAGASGTMGDIDAMAVGLAAWRLGAGRSR 360 GTAMDRFR LVAAQGGDLSKPLPIGSHSETVTAGASGTMGDIDAMAVGLAAWRLGAGRSR Sbjct 301 GTAMDRFRWLVAAQGGDLSKPLPIGSHSETVTAGASGTMGDIDAMAVGLAAWRLGAGRSR 360 Query 361 PGARVQHGAGVRIHRRPGEPVVVGEPLFTLYTNAPERFGAARAELAGGWSIRDSPPQVRP 420 PGARVQHGAGVRIHRRPGEPVVVGEPLFTLYTNAPERFGAARAELAGGWSIRDSPPQVRP Sbjct 361 PGARVQHGAGVRIHRRPGEPVVVGEPLFTLYTNAPERFGAARAELAGGWSIRDSPPQVRP 420 Query 421 LIVDRIV 427 LIVDRIV Sbjct 421 LIVDRIV 427 >gi|118617050|ref|YP_905382.1| thymidine phosphorylase [Mycobacterium ulcerans Agy99] gi|118569160|gb|ABL03911.1| thymidine phosphorylase DeoA [Mycobacterium ulcerans Agy99] Length=433 Score = 734 bits (1895), Expect = 0.0, Method: Compositional matrix adjust. Identities = 369/431 (86%), Positives = 395/431 (92%), Gaps = 5/431 (1%) Query 1 VTDFAFDAPTVIRTKRDGGRLSDAAIDWVVKAYTDGRVADEQMSALLMAIVWRGMDRGEI 60 +TDF FDAPTVIR KRDGGRLSDAAIDWV+ AYT+GRVA EQMSALLMAIV +GMDRGE Sbjct 1 MTDFEFDAPTVIRIKRDGGRLSDAAIDWVIDAYTEGRVAPEQMSALLMAIVLQGMDRGET 60 Query 61 ARWTAAMLASGARLDFTDL-----PLATVDKHSTGGVGDKITLPLVPVVAACGGAVPQAS 115 ARWT+AMLASG RLDF+DL PL TVDKHSTGGVGDKITLPLVPVV ACGG VPQAS Sbjct 61 ARWTSAMLASGPRLDFSDLRAGGAPLVTVDKHSTGGVGDKITLPLVPVVVACGGTVPQAS 120 Query 116 GRGLGHTGGTLDKLESITGFTANLSNQRVREQLCDVGAAIFAAGQLAPADAKLYALRDIT 175 GRGLGHTGGTLDKLESI+G TA LSNQ+VREQLCDVGAAIFAAG+LAPADAKLYALRDIT Sbjct 121 GRGLGHTGGTLDKLESISGLTATLSNQQVREQLCDVGAAIFAAGELAPADAKLYALRDIT 180 Query 176 GTVESLPLIASSIMSKKLAEGAGALVLDVKVGSGAFMRSPVQARELAHTMVELGAAHGVP 235 GTVESLPLIASSIMSKKLAEGAGALVLDVKVGSGAF++S Q+RELAHTMVELGAAHGVP Sbjct 181 GTVESLPLIASSIMSKKLAEGAGALVLDVKVGSGAFLKSETQSRELAHTMVELGAAHGVP 240 Query 236 TRALLTEMNCPLGRTVGNALEVAEALEVLAGGGPPDVVELTLRLAGEMLELAGIHGRDPA 295 TRALLT+MNCPLG TVGNALEVAEALEVL GGGPPDVVELT+RLA EML+L GI GRDPA Sbjct 241 TRALLTDMNCPLGSTVGNALEVAEALEVLDGGGPPDVVELTVRLAAEMLDLVGIDGRDPA 300 Query 296 QTLRDGTAMDRFRRLVAAQGGDLSKPLPIGSHSETVTAGASGTMGDIDAMAVGLAAWRLG 355 +TLRDG+AMDRFRRL+AAQGG+L+KPLPIG+HSETV AG GTMGDIDAMAVGLAAWRLG Sbjct 301 ETLRDGSAMDRFRRLIAAQGGELAKPLPIGAHSETVRAGRGGTMGDIDAMAVGLAAWRLG 360 Query 356 AGRSRPGARVQHGAGVRIHRRPGEPVVVGEPLFTLYTNAPERFGAARAELAGGWSIRDSP 415 AGRSRPGARVQHGAG+RIHRRPGEPV GEPLFTLYT+ PERFGAA AELA G+S+ DS Sbjct 361 AGRSRPGARVQHGAGIRIHRRPGEPVAAGEPLFTLYTDTPERFGAAVAELAAGFSVADSA 420 Query 416 PQVRPLIVDRI 426 P RPLI+DRI Sbjct 421 PTTRPLIIDRI 431 >gi|183981227|ref|YP_001849518.1| thymidine phosphorylase DeoA [Mycobacterium marinum M] gi|183174553|gb|ACC39663.1| thymidine phosphorylase DeoA [Mycobacterium marinum M] Length=433 Score = 734 bits (1895), Expect = 0.0, Method: Compositional matrix adjust. Identities = 369/431 (86%), Positives = 395/431 (92%), Gaps = 5/431 (1%) Query 1 VTDFAFDAPTVIRTKRDGGRLSDAAIDWVVKAYTDGRVADEQMSALLMAIVWRGMDRGEI 60 +TDF FDAPTVIR KRDGGRLSDAAIDWV+ AYT+GRVA EQMSALLMAIV +GMDRGE Sbjct 1 MTDFEFDAPTVIRIKRDGGRLSDAAIDWVIDAYTEGRVAPEQMSALLMAIVLQGMDRGET 60 Query 61 ARWTAAMLASGARLDFTDL-----PLATVDKHSTGGVGDKITLPLVPVVAACGGAVPQAS 115 ARWT+AMLASG RLDF+DL PL TVDKHSTGGVGDKITLPLVPVV ACGG VPQAS Sbjct 61 ARWTSAMLASGPRLDFSDLRAGGAPLVTVDKHSTGGVGDKITLPLVPVVVACGGTVPQAS 120 Query 116 GRGLGHTGGTLDKLESITGFTANLSNQRVREQLCDVGAAIFAAGQLAPADAKLYALRDIT 175 GRGLGHTGGTLDKLESI+GFTA LSNQ+VREQLCDVGAAIFAAG+LAPADAKLYALRDIT Sbjct 121 GRGLGHTGGTLDKLESISGFTATLSNQQVREQLCDVGAAIFAAGELAPADAKLYALRDIT 180 Query 176 GTVESLPLIASSIMSKKLAEGAGALVLDVKVGSGAFMRSPVQARELAHTMVELGAAHGVP 235 GTVESLPLIASSIMSKKLAEGAGALVLDVKVGSGAF++S Q+RELAHTMVELGAAHGVP Sbjct 181 GTVESLPLIASSIMSKKLAEGAGALVLDVKVGSGAFLKSETQSRELAHTMVELGAAHGVP 240 Query 236 TRALLTEMNCPLGRTVGNALEVAEALEVLAGGGPPDVVELTLRLAGEMLELAGIHGRDPA 295 TRALLT+MNCPLG TVGNALEVAEALEVL GGGPPDVVELT+RLA EML+L GI G DPA Sbjct 241 TRALLTDMNCPLGSTVGNALEVAEALEVLDGGGPPDVVELTVRLAAEMLDLVGIDGLDPA 300 Query 296 QTLRDGTAMDRFRRLVAAQGGDLSKPLPIGSHSETVTAGASGTMGDIDAMAVGLAAWRLG 355 +TLRDG+AMDRFRRL+AAQGG+L+KPLPIG+HSETV AG GTMGDIDAMAVGLAAWRLG Sbjct 301 ETLRDGSAMDRFRRLIAAQGGELAKPLPIGAHSETVRAGRGGTMGDIDAMAVGLAAWRLG 360 Query 356 AGRSRPGARVQHGAGVRIHRRPGEPVVVGEPLFTLYTNAPERFGAARAELAGGWSIRDSP 415 AGRSRPGARVQHGAG+RIHRRPGEPV GEPLFTLYT+ PERFGAA AELA G+S+ DS Sbjct 361 AGRSRPGARVQHGAGIRIHRRPGEPVAAGEPLFTLYTDTPERFGAAVAELAAGFSVADSA 420 Query 416 PQVRPLIVDRI 426 P RPLI+DRI Sbjct 421 PTTRPLIIDRI 431 >gi|240169121|ref|ZP_04747780.1| thymidine phosphorylase [Mycobacterium kansasii ATCC 12478] Length=428 Score = 724 bits (1869), Expect = 0.0, Method: Compositional matrix adjust. Identities = 367/426 (87%), Positives = 391/426 (92%), Gaps = 0/426 (0%) Query 1 VTDFAFDAPTVIRTKRDGGRLSDAAIDWVVKAYTDGRVADEQMSALLMAIVWRGMDRGEI 60 +TDF FDAPTVIRTKRDGGRLSDAAIDWV++A+TDGRVA EQMSALLMAI WRGMD GE Sbjct 1 MTDFEFDAPTVIRTKRDGGRLSDAAIDWVIQAFTDGRVAPEQMSALLMAIFWRGMDSGET 60 Query 61 ARWTAAMLASGARLDFTDLPLATVDKHSTGGVGDKITLPLVPVVAACGGAVPQASGRGLG 120 ARWT+AMLASG R+DF DL L TVDKHSTGGVGDKITLPLVPVV ACG AVPQA+GRGLG Sbjct 61 ARWTSAMLASGTRMDFADLRLPTVDKHSTGGVGDKITLPLVPVVVACGAAVPQAAGRGLG 120 Query 121 HTGGTLDKLESITGFTANLSNQRVREQLCDVGAAIFAAGQLAPADAKLYALRDITGTVES 180 HTGGTLDKLESI+GFTA LSNQRVR+QLCDVGAAIFAAG+LAPADAKLYALRDITGTVES Sbjct 121 HTGGTLDKLESISGFTATLSNQRVRQQLCDVGAAIFAAGELAPADAKLYALRDITGTVES 180 Query 181 LPLIASSIMSKKLAEGAGALVLDVKVGSGAFMRSPVQARELAHTMVELGAAHGVPTRALL 240 LPLIASSIMSKKLAEGAGALVLDVKVG+GAF++S Q+RELA TMV+LGAAHGVPTRALL Sbjct 181 LPLIASSIMSKKLAEGAGALVLDVKVGAGAFLKSEAQSRELARTMVDLGAAHGVPTRALL 240 Query 241 TEMNCPLGRTVGNALEVAEALEVLAGGGPPDVVELTLRLAGEMLELAGIHGRDPAQTLRD 300 T+MN PLGRTVGN+LEVAEALEVLAGGGP DVVELT+RLAGEML+LAGI RDPAQTLRD Sbjct 241 TDMNSPLGRTVGNSLEVAEALEVLAGGGPLDVVELTVRLAGEMLQLAGIDRRDPAQTLRD 300 Query 301 GTAMDRFRRLVAAQGGDLSKPLPIGSHSETVTAGASGTMGDIDAMAVGLAAWRLGAGRSR 360 G+AMDRFRRLV AQGGDLSKPLPIG SETVTA SGTMGDIDAMAVGLAAWRLGAGRSR Sbjct 301 GSAMDRFRRLVDAQGGDLSKPLPIGRCSETVTADRSGTMGDIDAMAVGLAAWRLGAGRSR 360 Query 361 PGARVQHGAGVRIHRRPGEPVVVGEPLFTLYTNAPERFGAARAELAGGWSIRDSPPQVRP 420 PGARVQHGAGVRIHRRPGEPVV GEPLFTLYT PERFG A A L GGWS+ ++ P RP Sbjct 361 PGARVQHGAGVRIHRRPGEPVVAGEPLFTLYTETPERFGPALAMLDGGWSVGEAGPAPRP 420 Query 421 LIVDRI 426 LI+DRI Sbjct 421 LIIDRI 426 >gi|342861540|ref|ZP_08718187.1| thymidine phosphorylase [Mycobacterium colombiense CECT 3035] gi|342131029|gb|EGT84318.1| thymidine phosphorylase [Mycobacterium colombiense CECT 3035] Length=428 Score = 701 bits (1808), Expect = 0.0, Method: Compositional matrix adjust. Identities = 360/427 (85%), Positives = 382/427 (90%), Gaps = 0/427 (0%) Query 1 VTDFAFDAPTVIRTKRDGGRLSDAAIDWVVKAYTDGRVADEQMSALLMAIVWRGMDRGEI 60 +T+ AFDAPTVIRTKRDGGRLSDAAIDWV+ AYTDGRVA+EQM+ALLMAI+ RGMD GE Sbjct 1 MTESAFDAPTVIRTKRDGGRLSDAAIDWVIGAYTDGRVAEEQMAALLMAILLRGMDPGET 60 Query 61 ARWTAAMLASGARLDFTDLPLATVDKHSTGGVGDKITLPLVPVVAACGGAVPQASGRGLG 120 ARWTAAMLASG LDF DL L TVDKHSTGGVGDKITLPLVPVVAACG AVPQASGRGLG Sbjct 61 ARWTAAMLASGDTLDFGDLGLTTVDKHSTGGVGDKITLPLVPVVAACGAAVPQASGRGLG 120 Query 121 HTGGTLDKLESITGFTANLSNQRVREQLCDVGAAIFAAGQLAPADAKLYALRDITGTVES 180 HTGGTLDKLESI GF+A LS++RVREQL DVGAAIFAAG LAPADAKLYALRDIT TVES Sbjct 121 HTGGTLDKLESIAGFSAELSSRRVREQLRDVGAAIFAAGDLAPADAKLYALRDITATVES 180 Query 181 LPLIASSIMSKKLAEGAGALVLDVKVGSGAFMRSPVQARELAHTMVELGAAHGVPTRALL 240 LPLIASSIMSKKLAEGAGALVLDVKVGSGA + S Q+RELAHTMVELGAAHGVPTRALL Sbjct 181 LPLIASSIMSKKLAEGAGALVLDVKVGSGALLASEAQSRELAHTMVELGAAHGVPTRALL 240 Query 241 TEMNCPLGRTVGNALEVAEALEVLAGGGPPDVVELTLRLAGEMLELAGIHGRDPAQTLRD 300 T+MN PLG TVGNALEVAE+LEVLAGGGPPDVVELTLRLA EMLELAGI RDPA TLRD Sbjct 241 TDMNRPLGATVGNALEVAESLEVLAGGGPPDVVELTLRLATEMLELAGIDDRDPADTLRD 300 Query 301 GTAMDRFRRLVAAQGGDLSKPLPIGSHSETVTAGASGTMGDIDAMAVGLAAWRLGAGRSR 360 GTAMDRFRRL+AAQGGDL+ PLP+ H+ETV A A GTMGDIDAMAVGL AWRLGAGRSR Sbjct 301 GTAMDRFRRLIAAQGGDLTVPLPVAGHAETVIAPAGGTMGDIDAMAVGLGAWRLGAGRSR 360 Query 361 PGARVQHGAGVRIHRRPGEPVVVGEPLFTLYTNAPERFGAARAELAGGWSIRDSPPQVRP 420 PG RVQ GAG+RIHRRPGEPV GEPLFTLYT+ PERF AA AEL GGWS+ +PP RP Sbjct 361 PGERVQLGAGIRIHRRPGEPVTAGEPLFTLYTDTPERFAAALAELDGGWSVERTPPASRP 420 Query 421 LIVDRIV 427 LI+DRIV Sbjct 421 LIIDRIV 427 >gi|254820238|ref|ZP_05225239.1| thymidine phosphorylase [Mycobacterium intracellulare ATCC 13950] Length=427 Score = 693 bits (1789), Expect = 0.0, Method: Compositional matrix adjust. Identities = 355/422 (85%), Positives = 379/422 (90%), Gaps = 0/422 (0%) Query 5 AFDAPTVIRTKRDGGRLSDAAIDWVVKAYTDGRVADEQMSALLMAIVWRGMDRGEIARWT 64 AFDAPTVIRTKRDGGRLSDAAIDWVV AYT GRVA+EQM+ALLMAI+ RGMDRGE ARWT Sbjct 4 AFDAPTVIRTKRDGGRLSDAAIDWVVDAYTAGRVAEEQMAALLMAILLRGMDRGETARWT 63 Query 65 AAMLASGARLDFTDLPLATVDKHSTGGVGDKITLPLVPVVAACGGAVPQASGRGLGHTGG 124 +AMLASG RLDF DL + TVDKHSTGGVGDKITLPLVPVVAACG AVPQASGRGLGHTGG Sbjct 64 SAMLASGERLDFGDLGVPTVDKHSTGGVGDKITLPLVPVVAACGAAVPQASGRGLGHTGG 123 Query 125 TLDKLESITGFTANLSNQRVREQLCDVGAAIFAAGQLAPADAKLYALRDITGTVESLPLI 184 TLDKLESI GFTA LSN+RVR+QL D+GAAIFAAG LAPADAKLYALRDIT TVESLPLI Sbjct 124 TLDKLESIAGFTAALSNRRVRDQLRDLGAAIFAAGDLAPADAKLYALRDITATVESLPLI 183 Query 185 ASSIMSKKLAEGAGALVLDVKVGSGAFMRSPVQARELAHTMVELGAAHGVPTRALLTEMN 244 ASS+MSKKLAEGAGALVLDVKVGSGAF S Q+R+LA TMV LGAAHGVPTRALLT+MN Sbjct 184 ASSVMSKKLAEGAGALVLDVKVGSGAFTDSEAQSRDLASTMVALGAAHGVPTRALLTDMN 243 Query 245 CPLGRTVGNALEVAEALEVLAGGGPPDVVELTLRLAGEMLELAGIHGRDPAQTLRDGTAM 304 PLG TVGNALEVAE+LEVLAGGGPPDVVELTLRLA EMLELAG+ GRDPA+TLRDGTAM Sbjct 244 TPLGATVGNALEVAESLEVLAGGGPPDVVELTLRLASEMLELAGVDGRDPAETLRDGTAM 303 Query 305 DRFRRLVAAQGGDLSKPLPIGSHSETVTAGASGTMGDIDAMAVGLAAWRLGAGRSRPGAR 364 DRFR+LVAAQGGDLS PLPI H+ETVTA GTMGDIDAMAVGLAAWRLGAGRSRPG R Sbjct 304 DRFRQLVAAQGGDLSVPLPIARHAETVTAARGGTMGDIDAMAVGLAAWRLGAGRSRPGDR 363 Query 365 VQHGAGVRIHRRPGEPVVVGEPLFTLYTNAPERFGAARAELAGGWSIRDSPPQVRPLIVD 424 VQ GAG+R+HRRPGEPV GEPLFTLYT+ PERFGAA AEL G + + D+ P RPLI+D Sbjct 364 VQFGAGIRLHRRPGEPVTAGEPLFTLYTDTPERFGAALAELDGAFGVGDAAPASRPLIID 423 Query 425 RI 426 RI Sbjct 424 RI 425 >gi|254776728|ref|ZP_05218244.1| thymidine phosphorylase [Mycobacterium avium subsp. avium ATCC 25291] Length=427 Score = 677 bits (1747), Expect = 0.0, Method: Compositional matrix adjust. Identities = 351/422 (84%), Positives = 376/422 (90%), Gaps = 0/422 (0%) Query 6 FDAPTVIRTKRDGGRLSDAAIDWVVKAYTDGRVADEQMSALLMAIVWRGMDRGEIARWTA 65 FDAPTVIRTKRDGGRLSDAAIDWV+ AYT G VA+EQM+ALLMAI+ RGMD GE A WT+ Sbjct 5 FDAPTVIRTKRDGGRLSDAAIDWVIDAYTRGLVAEEQMAALLMAILVRGMDGGETAAWTS 64 Query 66 AMLASGARLDFTDLPLATVDKHSTGGVGDKITLPLVPVVAACGGAVPQASGRGLGHTGGT 125 AMLASG RLDF+DL + TVDKHSTGGVGDKITLPLVPVVAACG AVPQASGRGLGHTGGT Sbjct 65 AMLASGDRLDFSDLGVPTVDKHSTGGVGDKITLPLVPVVAACGAAVPQASGRGLGHTGGT 124 Query 126 LDKLESITGFTANLSNQRVREQLCDVGAAIFAAGQLAPADAKLYALRDITGTVESLPLIA 185 LDKL++I GF+A L ++RVREQL +VGAAIFAAG LAPADAKLYALRDIT TVESLPLIA Sbjct 125 LDKLDAIAGFSAQLPSRRVREQLREVGAAIFAAGDLAPADAKLYALRDITATVESLPLIA 184 Query 186 SSIMSKKLAEGAGALVLDVKVGSGAFMRSPVQARELAHTMVELGAAHGVPTRALLTEMNC 245 SS+MSKKLAEGAGALVLDVKVGSGA +++ Q R+LAHTMV LGAAHGVPTRALLT+MN Sbjct 185 SSVMSKKLAEGAGALVLDVKVGSGALVKTEEQCRDLAHTMVGLGAAHGVPTRALLTDMNR 244 Query 246 PLGRTVGNALEVAEALEVLAGGGPPDVVELTLRLAGEMLELAGIHGRDPAQTLRDGTAMD 305 PLG TVGNALEVAEALEVLAGGGPPDVVELTLRLA EML LAG+ RDPA TLRDGTAMD Sbjct 245 PLGATVGNALEVAEALEVLAGGGPPDVVELTLRLAAEMLALAGVGDRDPADTLRDGTAMD 304 Query 306 RFRRLVAAQGGDLSKPLPIGSHSETVTAGASGTMGDIDAMAVGLAAWRLGAGRSRPGARV 365 RFRRLVAAQGGDLS PLPIG HSETVTA GTMGDIDAMAVGLAAWRLGAGRSRPG RV Sbjct 305 RFRRLVAAQGGDLSVPLPIGRHSETVTAPRGGTMGDIDAMAVGLAAWRLGAGRSRPGERV 364 Query 366 QHGAGVRIHRRPGEPVVVGEPLFTLYTNAPERFGAARAELAGGWSIRDSPPQVRPLIVDR 425 Q GAG+RIHRRPGEPV GEPLFTLYT+ PERFGAA AEL GGW++ D P RPLI+DR Sbjct 365 QAGAGLRIHRRPGEPVAAGEPLFTLYTDTPERFGAALAELDGGWNVGDGAPAPRPLIIDR 424 Query 426 IV 427 IV Sbjct 425 IV 426 >gi|41409537|ref|NP_962373.1| thymidine phosphorylase [Mycobacterium avium subsp. paratuberculosis K-10] gi|41398368|gb|AAS05989.1| DeoA [Mycobacterium avium subsp. paratuberculosis K-10] Length=427 Score = 674 bits (1739), Expect = 0.0, Method: Compositional matrix adjust. Identities = 350/422 (83%), Positives = 374/422 (89%), Gaps = 0/422 (0%) Query 6 FDAPTVIRTKRDGGRLSDAAIDWVVKAYTDGRVADEQMSALLMAIVWRGMDRGEIARWTA 65 FDAPTVIRTKRDGGRLSDAAIDWV+ AYT G VA+EQM+ALLMAI+ RGMD GE A WT+ Sbjct 5 FDAPTVIRTKRDGGRLSDAAIDWVIDAYTGGLVAEEQMAALLMAILLRGMDGGETAAWTS 64 Query 66 AMLASGARLDFTDLPLATVDKHSTGGVGDKITLPLVPVVAACGGAVPQASGRGLGHTGGT 125 AMLASG RLDF+DL + TVDKHSTGGVGDKITLPLVPVVAACG AVPQASGRGLGHTGGT Sbjct 65 AMLASGDRLDFSDLGVPTVDKHSTGGVGDKITLPLVPVVAACGAAVPQASGRGLGHTGGT 124 Query 126 LDKLESITGFTANLSNQRVREQLCDVGAAIFAAGQLAPADAKLYALRDITGTVESLPLIA 185 LDKL++I GF+A L ++RVREQL +VGAAIFAAG LAPADAKLYALRDIT TVESLPLIA Sbjct 125 LDKLDAIAGFSAQLPSRRVREQLREVGAAIFAAGDLAPADAKLYALRDITATVESLPLIA 184 Query 186 SSIMSKKLAEGAGALVLDVKVGSGAFMRSPVQARELAHTMVELGAAHGVPTRALLTEMNC 245 SS+MSKKLAEGAGALVLDVKVGSGA +++ Q R+LAHTMV LGAAHGVPTRALLT+MN Sbjct 185 SSVMSKKLAEGAGALVLDVKVGSGALVKTEEQCRDLAHTMVGLGAAHGVPTRALLTDMNR 244 Query 246 PLGRTVGNALEVAEALEVLAGGGPPDVVELTLRLAGEMLELAGIHGRDPAQTLRDGTAMD 305 PLG TVGNALEVAEALEVLAGGGP DVVELTLRLA EML LAG+ RDPA TLRDGTAMD Sbjct 245 PLGATVGNALEVAEALEVLAGGGPADVVELTLRLAAEMLALAGVGDRDPADTLRDGTAMD 304 Query 306 RFRRLVAAQGGDLSKPLPIGSHSETVTAGASGTMGDIDAMAVGLAAWRLGAGRSRPGARV 365 RFRRLVAAQGGDLS PLPIG HSETVTA GTMGDIDAMAVGLAAWRLGAGRSRPG RV Sbjct 305 RFRRLVAAQGGDLSVPLPIGRHSETVTAPRGGTMGDIDAMAVGLAAWRLGAGRSRPGERV 364 Query 366 QHGAGVRIHRRPGEPVVVGEPLFTLYTNAPERFGAARAELAGGWSIRDSPPQVRPLIVDR 425 Q GAG+RIHR PGEPV GEPLFTLYT+ PERFGAA AEL GGWS+ D P RPLI+DR Sbjct 365 QAGAGLRIHRHPGEPVAAGEPLFTLYTDTPERFGAALAELDGGWSVGDGAPAPRPLIIDR 424 Query 426 IV 427 IV Sbjct 425 IV 426 >gi|336459595|gb|EGO38530.1| pyrimidine-nucleoside phosphorylase [Mycobacterium avium subsp. paratuberculosis S397] Length=427 Score = 674 bits (1738), Expect = 0.0, Method: Compositional matrix adjust. Identities = 349/422 (83%), Positives = 374/422 (89%), Gaps = 0/422 (0%) Query 6 FDAPTVIRTKRDGGRLSDAAIDWVVKAYTDGRVADEQMSALLMAIVWRGMDRGEIARWTA 65 FDAPTVIRTKRDGGRLSDAAIDWV+ AYT G VA+EQM+ALLMAI+ RGMD GE A WT+ Sbjct 5 FDAPTVIRTKRDGGRLSDAAIDWVIDAYTGGLVAEEQMAALLMAILLRGMDGGETAAWTS 64 Query 66 AMLASGARLDFTDLPLATVDKHSTGGVGDKITLPLVPVVAACGGAVPQASGRGLGHTGGT 125 AMLASG RLDF+DL + TVDKHSTGGVGDKITLPLVPVVAACG AVPQASGRGLGHTGGT Sbjct 65 AMLASGDRLDFSDLGVPTVDKHSTGGVGDKITLPLVPVVAACGAAVPQASGRGLGHTGGT 124 Query 126 LDKLESITGFTANLSNQRVREQLCDVGAAIFAAGQLAPADAKLYALRDITGTVESLPLIA 185 LDKL++I GF+A L ++RVREQL +VGAAIFAAG LAPADAKLYALRDIT TVESLPLIA Sbjct 125 LDKLDAIAGFSAQLPSRRVREQLREVGAAIFAAGDLAPADAKLYALRDITATVESLPLIA 184 Query 186 SSIMSKKLAEGAGALVLDVKVGSGAFMRSPVQARELAHTMVELGAAHGVPTRALLTEMNC 245 SS+MSKKLAEGAGALVLDVKVGSGA +++ Q R+LAHTMV LGAAHGVPTRALLT+MN Sbjct 185 SSVMSKKLAEGAGALVLDVKVGSGALVKTEEQCRDLAHTMVGLGAAHGVPTRALLTDMNR 244 Query 246 PLGRTVGNALEVAEALEVLAGGGPPDVVELTLRLAGEMLELAGIHGRDPAQTLRDGTAMD 305 PLG T+GNALEVAEALEVLAGGGP DVVELTLRLA EML LAG+ RDPA TLRDGTAMD Sbjct 245 PLGATIGNALEVAEALEVLAGGGPADVVELTLRLAAEMLALAGVGDRDPADTLRDGTAMD 304 Query 306 RFRRLVAAQGGDLSKPLPIGSHSETVTAGASGTMGDIDAMAVGLAAWRLGAGRSRPGARV 365 RFRRLVAAQGGDLS PLPIG HSETVTA GTMGDIDAMAVGLAAWRLGAGRSRPG RV Sbjct 305 RFRRLVAAQGGDLSVPLPIGRHSETVTAPRGGTMGDIDAMAVGLAAWRLGAGRSRPGERV 364 Query 366 QHGAGVRIHRRPGEPVVVGEPLFTLYTNAPERFGAARAELAGGWSIRDSPPQVRPLIVDR 425 Q GAG+RIHR PGEPV GEPLFTLYT+ PERFGAA AEL GGWS+ D P RPLI+DR Sbjct 365 QAGAGLRIHRHPGEPVAAGEPLFTLYTDTPERFGAALAELDGGWSVGDGAPAPRPLIIDR 424 Query 426 IV 427 IV Sbjct 425 IV 426 >gi|118467210|ref|YP_883433.1| thymidine phosphorylase [Mycobacterium avium 104] gi|118168497|gb|ABK69394.1| thymidine phosphorylase [Mycobacterium avium 104] Length=427 Score = 673 bits (1736), Expect = 0.0, Method: Compositional matrix adjust. Identities = 349/422 (83%), Positives = 375/422 (89%), Gaps = 0/422 (0%) Query 6 FDAPTVIRTKRDGGRLSDAAIDWVVKAYTDGRVADEQMSALLMAIVWRGMDRGEIARWTA 65 FDAPTVIRTKRDGGRLSDAAIDWV+ AYT G VA+EQM+ALLMAI+ RGMD GE A WT+ Sbjct 5 FDAPTVIRTKRDGGRLSDAAIDWVIDAYTRGLVAEEQMAALLMAILLRGMDGGETAAWTS 64 Query 66 AMLASGARLDFTDLPLATVDKHSTGGVGDKITLPLVPVVAACGGAVPQASGRGLGHTGGT 125 AMLASG RLDF+DL + TVDKHSTGGVGDKITLPLVPVVAACG AVPQASGRGLGHTGGT Sbjct 65 AMLASGDRLDFSDLGVPTVDKHSTGGVGDKITLPLVPVVAACGAAVPQASGRGLGHTGGT 124 Query 126 LDKLESITGFTANLSNQRVREQLCDVGAAIFAAGQLAPADAKLYALRDITGTVESLPLIA 185 LDKL++I GF+A L ++RVREQL +VGAAIFAAG LAPADAKLYALRDIT TVESLPLIA Sbjct 125 LDKLDAIAGFSAQLPSRRVREQLREVGAAIFAAGDLAPADAKLYALRDITATVESLPLIA 184 Query 186 SSIMSKKLAEGAGALVLDVKVGSGAFMRSPVQARELAHTMVELGAAHGVPTRALLTEMNC 245 SS+MSKKLAEGAGALVLDVKVGSGA +++ Q R+LAHTMV LGAAHGVPTRALLT+MN Sbjct 185 SSVMSKKLAEGAGALVLDVKVGSGALVKTEEQCRDLAHTMVGLGAAHGVPTRALLTDMNR 244 Query 246 PLGRTVGNALEVAEALEVLAGGGPPDVVELTLRLAGEMLELAGIHGRDPAQTLRDGTAMD 305 PLG TVGNALEVAEALEVLAGGGPPDVVELTLRLA EML LAG+ RDPA TL DGTAMD Sbjct 245 PLGATVGNALEVAEALEVLAGGGPPDVVELTLRLAAEMLALAGVGDRDPADTLHDGTAMD 304 Query 306 RFRRLVAAQGGDLSKPLPIGSHSETVTAGASGTMGDIDAMAVGLAAWRLGAGRSRPGARV 365 RFRRLVAAQGGDLS PLPIG HSETVTA GTMGDIDAMAVGLAAWRLGAGRSRPG RV Sbjct 305 RFRRLVAAQGGDLSVPLPIGRHSETVTAPRGGTMGDIDAMAVGLAAWRLGAGRSRPGERV 364 Query 366 QHGAGVRIHRRPGEPVVVGEPLFTLYTNAPERFGAARAELAGGWSIRDSPPQVRPLIVDR 425 Q GAG+RIHRRPGEPV GEPLFTL+T+ PERFGAA AEL GGW++ D P RPLI+DR Sbjct 365 QAGAGLRIHRRPGEPVAAGEPLFTLHTDTPERFGAALAELDGGWNVGDGAPAPRPLIIDR 424 Query 426 IV 427 IV Sbjct 425 IV 426 >gi|296168863|ref|ZP_06850535.1| pyrimidine-nucleoside phosphorylase [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295896480|gb|EFG76130.1| pyrimidine-nucleoside phosphorylase [Mycobacterium parascrofulaceum ATCC BAA-614] Length=432 Score = 673 bits (1736), Expect = 0.0, Method: Compositional matrix adjust. Identities = 355/423 (84%), Positives = 378/423 (90%), Gaps = 0/423 (0%) Query 5 AFDAPTVIRTKRDGGRLSDAAIDWVVKAYTDGRVADEQMSALLMAIVWRGMDRGEIARWT 64 AFDAPTVIRTKRDGGRLSDAAI WV+ AYT GRVA+EQMSALLMAI RGMD GE A WT Sbjct 9 AFDAPTVIRTKRDGGRLSDAAIAWVIDAYTHGRVAEEQMSALLMAIFLRGMDDGETASWT 68 Query 65 AAMLASGARLDFTDLPLATVDKHSTGGVGDKITLPLVPVVAACGGAVPQASGRGLGHTGG 124 AAMLASG RLDF DLPL TVDKHSTGGVGDK+TLPLV VVAACG AVPQASGRGLGHTGG Sbjct 69 AAMLASGDRLDFRDLPLPTVDKHSTGGVGDKLTLPLVAVVAACGAAVPQASGRGLGHTGG 128 Query 125 TLDKLESITGFTANLSNQRVREQLCDVGAAIFAAGQLAPADAKLYALRDITGTVESLPLI 184 TLDKLESI GFTA LSN+RVREQL DVGAAIFAAG+LAPADAKLYALRD+T TVESLPLI Sbjct 129 TLDKLESIAGFTAALSNRRVREQLRDVGAAIFAAGELAPADAKLYALRDVTATVESLPLI 188 Query 185 ASSIMSKKLAEGAGALVLDVKVGSGAFMRSPVQARELAHTMVELGAAHGVPTRALLTEMN 244 ASS+MSKKLAEG GALVLDVKVGSGA + + + RELAHTMV LGAAHGVPTRALLT+MN Sbjct 189 ASSVMSKKLAEGTGALVLDVKVGSGALLSTAERCRELAHTMVGLGAAHGVPTRALLTDMN 248 Query 245 CPLGRTVGNALEVAEALEVLAGGGPPDVVELTLRLAGEMLELAGIHGRDPAQTLRDGTAM 304 PLG TVGN+LEVAE+L+VLAGGGPPDVVELT+RLAGEMLELAG GRDPA+TLRDGTAM Sbjct 249 APLGSTVGNSLEVAESLDVLAGGGPPDVVELTVRLAGEMLELAGADGRDPAETLRDGTAM 308 Query 305 DRFRRLVAAQGGDLSKPLPIGSHSETVTAGASGTMGDIDAMAVGLAAWRLGAGRSRPGAR 364 DRFRRLVAAQGGDLS PLPIG+HSETVTA GTMGDIDAMAVG AAWRLGAGRSRPG R Sbjct 309 DRFRRLVAAQGGDLSVPLPIGAHSETVTASRGGTMGDIDAMAVGQAAWRLGAGRSRPGER 368 Query 365 VQHGAGVRIHRRPGEPVVVGEPLFTLYTNAPERFGAARAELAGGWSIRDSPPQVRPLIVD 424 VQ GAG+RIHRRPGE V GEPLFTLYT+ PERFGAA AEL GG+ + D+PP RPLI+D Sbjct 369 VQAGAGIRIHRRPGEAVAAGEPLFTLYTDTPERFGAALAELDGGYRVGDAPPAARPLIID 428 Query 425 RIV 427 RIV Sbjct 429 RIV 431 >gi|120402597|ref|YP_952426.1| thymidine phosphorylase [Mycobacterium vanbaalenii PYR-1] gi|119955415|gb|ABM12420.1| thymidine phosphorylase [Mycobacterium vanbaalenii PYR-1] Length=433 Score = 634 bits (1634), Expect = 1e-179, Method: Compositional matrix adjust. Identities = 321/431 (75%), Positives = 361/431 (84%), Gaps = 5/431 (1%) Query 1 VTDFAFDAPTVIRTKRDGGRLSDAAIDWVVKAYTDGRVADEQMSALLMAIVWRGMDRGEI 60 +T F FD P++IRTKRDGG LSD AIDWV+ AYT GRVA+ QMSALLMAI RGM GEI Sbjct 1 MTQFTFDMPSIIRTKRDGGVLSDDAIDWVIDAYTHGRVAEAQMSALLMAIFLRGMTNGEI 60 Query 61 ARWTAAMLASGARLDFTDL-----PLATVDKHSTGGVGDKITLPLVPVVAACGGAVPQAS 115 ARWTAAM+ SG RLDF+DL PLA VDKHSTGGVGDKIT+PLV VV ACGGAVPQA+ Sbjct 61 ARWTAAMVDSGERLDFSDLRRDGKPLALVDKHSTGGVGDKITIPLVSVVMACGGAVPQAA 120 Query 116 GRGLGHTGGTLDKLESITGFTANLSNQRVREQLCDVGAAIFAAGQLAPADAKLYALRDIT 175 GRGLGHTGGTLDKLESI GFTA +S ++R+QLC++GAAIFAAG+LAPAD K+YALRD+T Sbjct 121 GRGLGHTGGTLDKLESIPGFTAEISKTQIRQQLCELGAAIFAAGELAPADRKIYALRDVT 180 Query 176 GTVESLPLIASSIMSKKLAEGAGALVLDVKVGSGAFMRSPVQARELAHTMVELGAAHGVP 235 T ESLPLIASS+MSKK+AEG ALVLD KVGSGAF+++ ++RELA TMVELG AHGV Sbjct 181 ATTESLPLIASSVMSKKIAEGTRALVLDTKVGSGAFLKTEAESRELARTMVELGTAHGVR 240 Query 236 TRALLTEMNCPLGRTVGNALEVAEALEVLAGGGPPDVVELTLRLAGEMLELAGIHGRDPA 295 TRALLT+MN PLGRTVGNA+EVAE+LEVLAGGGP DVVELTL LA EM + AG+ G DPA Sbjct 241 TRALLTDMNTPLGRTVGNAVEVAESLEVLAGGGPDDVVELTLALAREMCDAAGLDGVDPA 300 Query 296 QTLRDGTAMDRFRRLVAAQGGDLSKPLPIGSHSETVTAGASGTMGDIDAMAVGLAAWRLG 355 +TLRDGTAMDRFR LVAAQGGD LP+G+HSETV+A GTMGDIDAMAVGLA WRLG Sbjct 301 ETLRDGTAMDRFRALVAAQGGDPDAALPLGAHSETVSAPRGGTMGDIDAMAVGLAVWRLG 360 Query 356 AGRSRPGARVQHGAGVRIHRRPGEPVVVGEPLFTLYTNAPERFGAARAELAGGWSIRDSP 415 AGRS PG +VQ GAG+RIHRRPGEPV GEPLFTLYT+ PER A +EL G WS+ D P Sbjct 361 AGRSAPGEQVQFGAGMRIHRRPGEPVAAGEPLFTLYTDTPERLAGAVSELDGAWSVGDEP 420 Query 416 PQVRPLIVDRI 426 P RPLI+DRI Sbjct 421 PARRPLIIDRI 431 >gi|126433860|ref|YP_001069551.1| thymidine phosphorylase [Mycobacterium sp. JLS] gi|126233660|gb|ABN97060.1| thymidine phosphorylase [Mycobacterium sp. JLS] Length=439 Score = 625 bits (1612), Expect = 4e-177, Method: Compositional matrix adjust. Identities = 323/435 (75%), Positives = 362/435 (84%), Gaps = 9/435 (2%) Query 1 VTDFAFDAPTVIRTKRDGGRLSDAAIDWVVKAYTDGRVADEQMSALLMAIVWRGMDRGEI 60 +TDF FDAPTVIR KRDGG L D AIDWV+ AYT G+VADEQMSALLMAI RGM EI Sbjct 1 MTDFTFDAPTVIRVKRDGGVLPDEAIDWVIDAYTRGQVADEQMSALLMAIFLRGMTGPEI 60 Query 61 ARWTAAMLASGARLDFTDL-----PLATVDKHSTGGVGDKITLPLVPVVAACGGAVPQAS 115 ARWTAAM+ASG R DFTDL PLA VDKHSTGGVGDKIT+PLVPVV ACGGAVPQA+ Sbjct 61 ARWTAAMVASGQRFDFTDLRRGGRPLALVDKHSTGGVGDKITIPLVPVVMACGGAVPQAA 120 Query 116 GRGLGHTGGTLDKLESITGFTANLSNQRVREQLCDVGAAIFAAGQLAPADAKLYALRDIT 175 GRGLGHTGGTLDKLE+I GFTA L+ ++R+QL ++GAAIFAAG+LAPAD K+YALRD+T Sbjct 121 GRGLGHTGGTLDKLEAIPGFTAELTKSQIRQQLSEIGAAIFAAGELAPADRKIYALRDVT 180 Query 176 GTVESLPLIASSIMSKKLAEGAGALVLDVKVGSGAFMRSPVQARELAHTMVELGAAHGVP 235 T ESLPLIASS+MSKK+AEGA ALVLD KVGSGAF+ + +ARELA TMVELG AHG+ Sbjct 181 ATTESLPLIASSVMSKKIAEGARALVLDTKVGSGAFLPTEAEARELARTMVELGHAHGLV 240 Query 236 TRALLTEMNCPLGRTVGNALEVAEALEVLAGGGPPDVVELTLRLAGEMLELAGIHGRDPA 295 TRALLT+M+ PLGR VGNA+EV E+LEVLAGGGP DVVELTL LA EML+ AGI G DPA Sbjct 241 TRALLTDMSVPLGRAVGNAVEVVESLEVLAGGGPDDVVELTLALAAEMLDAAGIDGTDPA 300 Query 296 QTLRDGTAMDRFRRLVAAQGGDLSK----PLPIGSHSETVTAGASGTMGDIDAMAVGLAA 351 +TLRDGTAMD FR LVAAQGGD ++ LPIG H++TVTA GTMGDIDAMAVGLA Sbjct 301 ETLRDGTAMDCFRALVAAQGGDTTRLAADALPIGVHTDTVTAPRGGTMGDIDAMAVGLAV 360 Query 352 WRLGAGRSRPGARVQHGAGVRIHRRPGEPVVVGEPLFTLYTNAPERFGAARAELAGGWSI 411 WRLGAGRS PG +VQ GAG+RIHRRPGEPV GEPLFTLYT+ P+R G ARAEL G W++ Sbjct 361 WRLGAGRSAPGEQVQFGAGLRIHRRPGEPVSAGEPLFTLYTDTPDRLGPARAELEGAWTV 420 Query 412 RDSPPQVRPLIVDRI 426 DS P RPLI+DRI Sbjct 421 GDSAPPARPLIIDRI 435 >gi|108798203|ref|YP_638400.1| thymidine phosphorylase [Mycobacterium sp. MCS] gi|119867299|ref|YP_937251.1| thymidine phosphorylase [Mycobacterium sp. KMS] gi|108768622|gb|ABG07344.1| thymidine phosphorylase [Mycobacterium sp. MCS] gi|119693388|gb|ABL90461.1| thymidine phosphorylase [Mycobacterium sp. KMS] Length=448 Score = 618 bits (1594), Expect = 5e-175, Method: Compositional matrix adjust. Identities = 324/444 (73%), Positives = 362/444 (82%), Gaps = 18/444 (4%) Query 1 VTDFAFDAP---------TVIRTKRDGGRLSDAAIDWVVKAYTDGRVADEQMSALLMAIV 51 +TDF FDAP TVIR KRDGG L D AIDWV+ AYT G+VADEQMSALLMAI Sbjct 1 MTDFTFDAPRPMSHLDAPTVIRVKRDGGDLPDEAIDWVIDAYTRGQVADEQMSALLMAIF 60 Query 52 WRGMDRGEIARWTAAMLASGARLDFTDL-----PLATVDKHSTGGVGDKITLPLVPVVAA 106 RGM EIARWTAAM+ASG R DFTDL PLA VDKHSTGGVGDKIT+PLVPVV A Sbjct 61 LRGMTGPEIARWTAAMVASGQRFDFTDLRRGGRPLALVDKHSTGGVGDKITIPLVPVVMA 120 Query 107 CGGAVPQASGRGLGHTGGTLDKLESITGFTANLSNQRVREQLCDVGAAIFAAGQLAPADA 166 CGGAVPQA+GRGLGHTGGTLDKLE+I GFTA L+ ++R+QL ++GAAIFAAG+LAPAD Sbjct 121 CGGAVPQAAGRGLGHTGGTLDKLEAIPGFTAELTKSQIRQQLSEIGAAIFAAGELAPADR 180 Query 167 KLYALRDITGTVESLPLIASSIMSKKLAEGAGALVLDVKVGSGAFMRSPVQARELAHTMV 226 K+YALRD+T T ESLPLIASS+MSKK+AEGA ALVLD KVGSGAF+ + +ARELA TMV Sbjct 181 KIYALRDVTATTESLPLIASSVMSKKIAEGARALVLDTKVGSGAFLPTEAEARELARTMV 240 Query 227 ELGAAHGVPTRALLTEMNCPLGRTVGNALEVAEALEVLAGGGPPDVVELTLRLAGEMLEL 286 ELG AHG+ TRALLT+M+ PLGR VGNA+EV E+LEVLAGGGP DVVELTL LA EML+ Sbjct 241 ELGHAHGLVTRALLTDMSVPLGRAVGNAVEVVESLEVLAGGGPDDVVELTLALAAEMLDA 300 Query 287 AGIHGRDPAQTLRDGTAMDRFRRLVAAQGGDLSK----PLPIGSHSETVTAGASGTMGDI 342 AGI G DPA+TLRDGTAMD FR LVAAQGGD S+ LPIG H++TVTA GTMGDI Sbjct 301 AGIDGTDPAETLRDGTAMDCFRALVAAQGGDTSRLAADALPIGVHTDTVTAPRGGTMGDI 360 Query 343 DAMAVGLAAWRLGAGRSRPGARVQHGAGVRIHRRPGEPVVVGEPLFTLYTNAPERFGAAR 402 DAMAVGLA WRLGAGRS PG +VQ GAG+RIHRRPGEPV GEPLFTLYT+ P+R G AR Sbjct 361 DAMAVGLAVWRLGAGRSAPGEQVQFGAGLRIHRRPGEPVSAGEPLFTLYTDTPDRLGPAR 420 Query 403 AELAGGWSIRDSPPQVRPLIVDRI 426 AEL G W++ DS P RPLI+DRI Sbjct 421 AELEGAWTVGDSAPPARPLIIDRI 444 >gi|145225420|ref|YP_001136098.1| thymidine phosphorylase [Mycobacterium gilvum PYR-GCK] gi|315445768|ref|YP_004078647.1| thymidine phosphorylase [Mycobacterium sp. Spyr1] gi|145217906|gb|ABP47310.1| thymidine phosphorylase [Mycobacterium gilvum PYR-GCK] gi|315264071|gb|ADU00813.1| thymidine phosphorylase [Mycobacterium sp. Spyr1] Length=443 Score = 615 bits (1585), Expect = 5e-174, Method: Compositional matrix adjust. Identities = 315/430 (74%), Positives = 353/430 (83%), Gaps = 9/430 (2%) Query 6 FDAPTVIRTKRDGGRLSDAAIDWVVKAYTDGRVADEQMSALLMAIVWRGMDRGEIARWTA 65 DAP+VIRTKRDGG LSD AIDWV+ AYT G VA+ QMSALLMAI RGM EIARWTA Sbjct 12 LDAPSVIRTKRDGGALSDEAIDWVIDAYTRGEVAEAQMSALLMAIFLRGMTGHEIARWTA 71 Query 66 AMLASGARLDFTDL-----PLATVDKHSTGGVGDKITLPLVPVVAACGGAVPQASGRGLG 120 AM+ASG RLDF+DL PLA VDKHSTGGVGDKIT+PLVPVV ACGGAVPQA+GRGLG Sbjct 72 AMIASGERLDFSDLRRDGKPLALVDKHSTGGVGDKITIPLVPVVMACGGAVPQAAGRGLG 131 Query 121 HTGGTLDKLESITGFTANLSNQRVREQLCDVGAAIFAAGQLAPADAKLYALRDITGTVES 180 HTGGTLDKLESI GFTA ++ ++R+QLCD+GAAIFAAG+LAPAD K+YALRD+T T ES Sbjct 132 HTGGTLDKLESIPGFTAEITKSQIRQQLCDLGAAIFAAGELAPADRKIYALRDVTATTES 191 Query 181 LPLIASSIMSKKLAEGAGALVLDVKVGSGAFMRSPVQARELAHTMVELGAAHGVPTRALL 240 LPLIASS+MSKK+AEG ALVLD KVGSGAF+ S ++RELA TMVELG HGV TRALL Sbjct 192 LPLIASSVMSKKIAEGTKALVLDSKVGSGAFLDSEAESRELARTMVELGVEHGVQTRALL 251 Query 241 TEMNCPLGRTVGNALEVAEALEVLAGGGPPDVVELTLRLAGEMLELAGIHGRDPAQTLRD 300 T+M PLGRTVGNA+EV E+LEVLAGGGP DVVELTL LA EM ++AG+ G DPAQTLRD Sbjct 252 TDMQTPLGRTVGNAVEVVESLEVLAGGGPDDVVELTLALAREMCDVAGLDGVDPAQTLRD 311 Query 301 GTAMDRFRRLVAAQGGDLSK----PLPIGSHSETVTAGASGTMGDIDAMAVGLAAWRLGA 356 GTAMDRFR LVAAQGGD+ LP+G H+ET++A SGTMGDIDAMAVGLA WRLGA Sbjct 312 GTAMDRFRDLVAAQGGDVDSLDAAMLPLGQHTETISAPRSGTMGDIDAMAVGLAVWRLGA 371 Query 357 GRSRPGARVQHGAGVRIHRRPGEPVVVGEPLFTLYTNAPERFGAARAELAGGWSIRDSPP 416 GRS PG +VQ GAG+RIHR+PGE V GEPLFTLYT P R AA +EL G WS+ D P Sbjct 372 GRSVPGEQVQFGAGMRIHRKPGEAVAAGEPLFTLYTETPHRLAAAASELDGAWSVGDHAP 431 Query 417 QVRPLIVDRI 426 RPLI+DRI Sbjct 432 PTRPLIIDRI 441 >gi|118470133|ref|YP_886051.1| thymidine phosphorylase [Mycobacterium smegmatis str. MC2 155] gi|118171420|gb|ABK72316.1| pyrimidine-nucleoside phosphorylase [Mycobacterium smegmatis str. MC2 155] Length=413 Score = 589 bits (1519), Expect = 3e-166, Method: Compositional matrix adjust. Identities = 304/411 (74%), Positives = 342/411 (84%), Gaps = 5/411 (1%) Query 21 LSDAAIDWVVKAYTDGRVADEQMSALLMAIVWRGMDRGEIARWTAAMLASGARLDFTDL- 79 LSD AIDWV+ YT GRVADEQMSALLMAI RGM GEI RWTAAM+ SG R DFTDL Sbjct 2 LSDDAIDWVIDNYTRGRVADEQMSALLMAIFLRGMTPGEITRWTAAMVNSGERFDFTDLE 61 Query 80 ----PLATVDKHSTGGVGDKITLPLVPVVAACGGAVPQASGRGLGHTGGTLDKLESITGF 135 PLA VDKHSTGGVGDK+T+PLVPVV ACG AVPQA+GRGLGHTGGTLDKLE+I GF Sbjct 62 RDGRPLALVDKHSTGGVGDKLTIPLVPVVIACGAAVPQAAGRGLGHTGGTLDKLEAIPGF 121 Query 136 TANLSNQRVREQLCDVGAAIFAAGQLAPADAKLYALRDITGTVESLPLIASSIMSKKLAE 195 +A L+ ++R+QLC VGAAIFAAG+LAPAD K+YALRD+T T ESLPLIASSIMSKKLAE Sbjct 122 SAELTKTQIRQQLCGVGAAIFAAGELAPADRKIYALRDVTATTESLPLIASSIMSKKLAE 181 Query 196 GAGALVLDVKVGSGAFMRSPVQARELAHTMVELGAAHGVPTRALLTEMNCPLGRTVGNAL 255 GA ALVLDVKVG GAF+++ ++RELA TMVELG +GVPTRALLT+MN PLG +VGNA+ Sbjct 182 GARALVLDVKVGRGAFLKTEAESRELARTMVELGNDYGVPTRALLTDMNRPLGLSVGNAV 241 Query 256 EVAEALEVLAGGGPPDVVELTLRLAGEMLELAGIHGRDPAQTLRDGTAMDRFRRLVAAQG 315 EVAE+L+VLAGGGP DVVELT+ LA EML AGI G DPA+TLRDG+AMDRFR LVAAQG Sbjct 242 EVAESLDVLAGGGPADVVELTVALAREMLAAAGIDGVDPAETLRDGSAMDRFRALVAAQG 301 Query 316 GDLSKPLPIGSHSETVTAGASGTMGDIDAMAVGLAAWRLGAGRSRPGARVQHGAGVRIHR 375 GDLS PLPIG+ SETVTA G MGDIDAM V +AAWRLGAGR++PG VQ GAGVR+HR Sbjct 302 GDLSLPLPIGAASETVTAPRGGVMGDIDAMGVAMAAWRLGAGRAQPGEPVQLGAGVRLHR 361 Query 376 RPGEPVVVGEPLFTLYTNAPERFGAARAELAGGWSIRDSPPQVRPLIVDRI 426 RPGEPV GE LFTLYT+ P+R AA EL G WS+ D+PPQ PLI+DRI Sbjct 362 RPGEPVAAGETLFTLYTDTPDRLPAALGELDGAWSVGDAPPQELPLIIDRI 412 >gi|333991781|ref|YP_004524395.1| thymidine phosphorylase DeoA [Mycobacterium sp. JDM601] gi|333487749|gb|AEF37141.1| thymidine phosphorylase DeoA [Mycobacterium sp. JDM601] Length=434 Score = 552 bits (1422), Expect = 4e-155, Method: Compositional matrix adjust. Identities = 319/427 (75%), Positives = 349/427 (82%), Gaps = 8/427 (1%) Query 5 AFDAPTVIRTKRDGGRLSDAAIDWVVKAYTDGRVADEQMSALLMAIVWRGMDRGEIARWT 64 +FDAPT+I KRDG RL DAAIDW++ +YT +A+EQM+ALLMAI RGMD E ARWT Sbjct 4 SFDAPTLIAAKRDGHRLPDAAIDWLIDSYTAAEIAEEQMAALLMAIFLRGMDAEETARWT 63 Query 65 AAMLASGARLDFTDLP-----LATVDKHSTGGVGDKITLPLVPVVAACGGAVPQASGRGL 119 AAM+ASG R+DF +L + TVDKHSTGGVGDKITLPLV VVAACG AVPQASGRGL Sbjct 64 AAMIASGERMDFRELRRDGRRVPTVDKHSTGGVGDKITLPLVAVVAACGAAVPQASGRGL 123 Query 120 GHTGGTLDKLESITGFTANLSNQRVREQLCDVGAAIFAAGQLAPADAKLYALRDITGTVE 179 GHTGGTLDKLESI GF L R+REQL +VGAAIFAAG LAPADAKLYALRDIT TVE Sbjct 124 GHTGGTLDKLESIAGFDPVLPTARLREQLAEVGAAIFAAGALAPADAKLYALRDITATVE 183 Query 180 SLPLIASSIMSKKLAEGAGALVLDVKVGSGAFMRSPVQARELAHTMVELGAAHGVPTRAL 239 SLPLIASS+MSKKLAEG GALVLDVKVGSGAFM+S AR+LA M+ELGAAHGVPTRAL Sbjct 184 SLPLIASSVMSKKLAEGTGALVLDVKVGSGAFMKSAGPARQLAELMIELGAAHGVPTRAL 243 Query 240 LTEMNCPLGRTVGNALEVAEALEVLAGGGPPDVVELTLRLAGEMLELAGIHGRDPAQTLR 299 LT+MN PLG TVGNALEVAEAL+VLAGGGP DVV LTL LA EMLELAG+ R+PA TL Sbjct 244 LTDMNSPLGATVGNALEVAEALDVLAGGGPEDVVALTLALATEMLELAGLDDREPAATLA 303 Query 300 DGTAMDRFRRLVAAQGGDLSKPLPIGSHSETVTAGASGTMGDIDAMAVGLAAWRLGAGRS 359 DGTAMD F +VAAQGGDLS LP+ + SETVTA GTMG+IDAMAVG+ AWRLGAGRS Sbjct 304 DGTAMDAFAAMVAAQGGDLSVALPVAACSETVTAPRDGTMGEIDAMAVGMTAWRLGAGRS 363 Query 360 RPGARVQHGAGVRIHRRPGEPVVVGEPLFTLYTNAPERFGAARAELAGGWSIRDSP---P 416 RPG RVQ GAGVRIHRRPGEPV GE LFTLYT+APERFG A AEL GG+ I P P Sbjct 364 RPGERVQAGAGVRIHRRPGEPVSAGEALFTLYTDAPERFGPAHAELDGGYRILSGPDAAP 423 Query 417 QVRPLIV 423 RPLI+ Sbjct 424 VPRPLII 430 >gi|169630750|ref|YP_001704399.1| thymidine phosphorylase [Mycobacterium abscessus ATCC 19977] gi|169242717|emb|CAM63745.1| Probable thymidine phosphorylase DeoA [Mycobacterium abscessus] Length=429 Score = 533 bits (1372), Expect = 3e-149, Method: Compositional matrix adjust. Identities = 291/424 (69%), Positives = 329/424 (78%), Gaps = 2/424 (0%) Query 4 FAFDAPTVIRTKRDGGRLSDAAIDWVVKAYTDGRVADEQMSALLMAIVWRGMDRGEIARW 63 +AFD P++I TKRDG LS AAIDW++ YT G + +EQ++ALLMAI RGM+ E A W Sbjct 5 YAFDMPSIIATKRDGAELSPAAIDWLIGQYTSGDIGEEQVAALLMAIYLRGMNGAETAAW 64 Query 64 TAAMLASGARLDFTDLPLATVDKHSTGGVGDKITLPLVPVVAACGGAVPQASGRGLGHTG 123 TAA+LASG RLD + L TVDKHSTGGVGDKI+LPLV VVAACG AVPQ SGRGLGHTG Sbjct 65 TAAILASGERLDLSGLSRPTVDKHSTGGVGDKISLPLVAVVAACGAAVPQLSGRGLGHTG 124 Query 124 GTLDKLESITGFTANLSNQRVREQLCDVGAAIFAAG-QLAPADAKLYALRDITGTVESLP 182 GTLDKLES+ G +LSN ++R+QL DVGA I AAG LAPAD KLYALRDITGTVES+P Sbjct 125 GTLDKLESVAGIRVDLSNDQIRQQLSDVGAVICAAGASLAPADRKLYALRDITGTVESIP 184 Query 183 LIASSIMSKKLAEGAGALVLDVKVGSGAFMRSPVQARELAHTMVELGAAHGVPTRALLTE 242 LIA SIM KKLAEG ALVLDVKVG+GAFM+S +ARELA MV+LG AHGV T ALLT Sbjct 185 LIAGSIMGKKLAEGTAALVLDVKVGAGAFMKSEQRARELASAMVDLGTAHGVATSALLTA 244 Query 243 MNCPLGRTVGNALEVAEALEVLAGGGPPDVVELTLRLAGEMLELAGIHGRDPAQTLRDGT 302 M+ PLG T GNA+EV E+L+VLAGGGP DVV LT+ LA EML AGI G+DPA TL DGT Sbjct 245 MDTPLGATAGNAVEVQESLDVLAGGGPEDVVALTVTLAREMLAAAGIDGKDPAATLTDGT 304 Query 303 AMDRFRRLVAAQGGDLSKPLPIGSHSETVTAGASGTMGDIDAMAVGLAAWRLGAGRSRPG 362 AMD FR ++ AQGGDL+ PLP+G ETV A G M IDAM VG+AAWRLGAGRSRPG Sbjct 305 AMDVFRTMIHAQGGDLAVPLPLGQCQETVLAPVGGVMRRIDAMPVGIAAWRLGAGRSRPG 364 Query 363 ARVQHGAGVRIHRRPGEPVVVGEPLFTLYTNAPERFGAARAELAGGWSIRDSPPQVRPLI 422 VQHGAGVRIHRRPGE VV GEPLFTLYT+ ER AA L GGW I + P PLI Sbjct 365 EAVQHGAGVRIHRRPGEAVVAGEPLFTLYTDTQERLPAALDALEGGWEI-GAAPTATPLI 423 Query 423 VDRI 426 +DR+ Sbjct 424 IDRL 427 >gi|226365718|ref|YP_002783501.1| thymidine phosphorylase [Rhodococcus opacus B4] gi|226244208|dbj|BAH54556.1| pyrimidine nucleoside phosphorylase [Rhodococcus opacus B4] Length=431 Score = 524 bits (1349), Expect = 1e-146, Method: Compositional matrix adjust. Identities = 282/425 (67%), Positives = 331/425 (78%), Gaps = 4/425 (0%) Query 6 FDAPTVIRTKRDGGRLSDAAIDWVVKAYTDGRVADEQMSALLMAIVWRGMDRGEIARWTA 65 DA ++I KRDG LS A IDWVV+A+T G VADEQMSAL MAI +RGM RGE++RWT Sbjct 2 HDASSIIAAKRDGRELSGAEIDWVVEAFTRGVVADEQMSALAMAIFFRGMTRGEVSRWTT 61 Query 66 AMLASGARLDFTDLPLATVDKHSTGGVGDKITLPLVPVVAACGGAVPQASGRGLGHTGGT 125 AM++SG RLDFT L TVDKHSTGGVGDKITLPL P+VAACG AVPQ SGRGLGHTGGT Sbjct 62 AMISSGHRLDFTHLGRPTVDKHSTGGVGDKITLPLAPLVAACGAAVPQLSGRGLGHTGGT 121 Query 126 LDKLESITGFTANLSNQRVREQLCD--VGAAIFAAGQ-LAPADAKLYALRDITGTVESLP 182 LDKLESI G+ A+L + E L D VGA + AAG LAPAD +LYALRD+TGTVES+P Sbjct 122 LDKLESIPGWRADLDTSEMAEILSDPEVGAVVCAAGSDLAPADRRLYALRDVTGTVESIP 181 Query 183 LIASSIMSKKLAEGAGALVLDVKVGSGAFMRSPVQARELAHTMVELGAAHGVPTRALLTE 242 LIASSIMSKK+AEG GALVLDVKVGSGAFM+ ARELA TMV+LG+ GV T A+LT Sbjct 182 LIASSIMSKKIAEGTGALVLDVKVGSGAFMKKLDDARELAQTMVDLGSDAGVRTMAVLTA 241 Query 243 MNCPLGRTVGNALEVAEALEVLAGGGPPDVVELTLRLAGEMLELAGIHGRDPAQTLRDGT 302 M+ PLG T GNALEV E+LEVLAGGGP DVVELTL LA EML+ AGI G DPA LRDG+ Sbjct 242 MDAPLGHTAGNALEVRESLEVLAGGGPSDVVELTLALAREMLKAAGIDGVDPADKLRDGS 301 Query 303 AMDRFRRLVAAQGGDLSKPLPIGSHSETVTAGASGTMGDIDAMAVGLAAWRLGAGRSRPG 362 AMDR+RR++AAQGGD PLP H+E + + + G + +DAMAVGLAAWRLGAGR+R G Sbjct 302 AMDRWRRMIAAQGGDPYAPLPTARHTEVLLSESDGVVCGLDAMAVGLAAWRLGAGRARQG 361 Query 363 ARVQHGAGVRIHRRPGEPVVVGEPLFTLYTNAPERFGAARAELAGGWS-IRDSPPQVRPL 421 VQ GAG+ +H +PGE V VG PL TL+T+ PERF AA+A L+ W+ + D+PP PL Sbjct 362 EPVQAGAGIELHAKPGETVSVGTPLVTLHTDTPERFAAAKAALSEAWTVVADAPPVTTPL 421 Query 422 IVDRI 426 +++RI Sbjct 422 VIERI 426 >gi|111023213|ref|YP_706185.1| thymidine phosphorylase [Rhodococcus jostii RHA1] gi|110822743|gb|ABG98027.1| thymidine phosphorylase [Rhodococcus jostii RHA1] Length=431 Score = 521 bits (1342), Expect = 9e-146, Method: Compositional matrix adjust. Identities = 279/425 (66%), Positives = 326/425 (77%), Gaps = 4/425 (0%) Query 6 FDAPTVIRTKRDGGRLSDAAIDWVVKAYTDGRVADEQMSALLMAIVWRGMDRGEIARWTA 65 DA ++I KRDG LS A IDWVV+A+T G VADEQMSAL MAI +RGM R E++RWT Sbjct 2 HDASSIIAAKRDGRELSGAEIDWVVEAFTRGVVADEQMSALAMAIYFRGMTREEVSRWTT 61 Query 66 AMLASGARLDFTDLPLATVDKHSTGGVGDKITLPLVPVVAACGGAVPQASGRGLGHTGGT 125 AM++SG RLDFT L TVDKHSTGGVGDK TLPL P+VAACG AVPQ SGRGLGHTGGT Sbjct 62 AMISSGRRLDFTHLGRPTVDKHSTGGVGDKTTLPLAPLVAACGAAVPQLSGRGLGHTGGT 121 Query 126 LDKLESITGFTANLSNQRVREQLCD--VGAAIFAAG-QLAPADAKLYALRDITGTVESLP 182 LDKLESI G+ A+L + E L D VGA + AAG LAPAD +LYALRD+TGTVES+P Sbjct 122 LDKLESIPGWRADLDTSEMAEILSDPAVGAVVCAAGADLAPADRRLYALRDVTGTVESIP 181 Query 183 LIASSIMSKKLAEGAGALVLDVKVGSGAFMRSPVQARELAHTMVELGAAHGVPTRALLTE 242 LIASSIMSKK+AEG GALVLDVKVGSGAFM+ ARELA TMV+LG GV T ALLT Sbjct 182 LIASSIMSKKIAEGTGALVLDVKVGSGAFMKKLDDARELAQTMVDLGNDAGVRTMALLTA 241 Query 243 MNCPLGRTVGNALEVAEALEVLAGGGPPDVVELTLRLAGEMLELAGIHGRDPAQTLRDGT 302 M+ PLG T GNALEV E+LEVLAGGGP DVVELTL LA EML+ A I G DPA LRDG+ Sbjct 242 MDAPLGHTAGNALEVRESLEVLAGGGPSDVVELTLELAREMLKAAEIDGVDPADKLRDGS 301 Query 303 AMDRFRRLVAAQGGDLSKPLPIGSHSETVTAGASGTMGDIDAMAVGLAAWRLGAGRSRPG 362 AMDR+RR++AAQGGD PLP H+E + + + G + +DAMAVGLAAWRLGAGR+R G Sbjct 302 AMDRWRRMIAAQGGDPDAPLPTARHTEVLLSESDGVVCGLDAMAVGLAAWRLGAGRARQG 361 Query 363 ARVQHGAGVRIHRRPGEPVVVGEPLFTLYTNAPERFGAARAELAGGWS-IRDSPPQVRPL 421 VQ GAG+ +H +PGE V VG PL TL+T+ PERF AA+A L+ W+ + D+P PL Sbjct 362 EPVQAGAGIELHAKPGETVSVGTPLVTLHTDTPERFAAAKAVLSEAWTVVADAPSVTTPL 421 Query 422 IVDRI 426 +++RI Sbjct 422 VIERI 426 >gi|229489381|ref|ZP_04383244.1| pyrimidine-nucleoside phosphorylase [Rhodococcus erythropolis SK121] gi|229323478|gb|EEN89236.1| pyrimidine-nucleoside phosphorylase [Rhodococcus erythropolis SK121] Length=431 Score = 520 bits (1339), Expect = 2e-145, Method: Compositional matrix adjust. Identities = 280/426 (66%), Positives = 323/426 (76%), Gaps = 4/426 (0%) Query 6 FDAPTVIRTKRDGGRLSDAAIDWVVKAYTDGRVADEQMSALLMAIVWRGMDRGEIARWTA 65 FDA ++I KRDG LS IDW+V+A+T G V DEQMSAL MAI +RGM R E RWT Sbjct 2 FDAVSIIGAKRDGRELSGTEIDWIVQAFTQGIVGDEQMSALAMAIYFRGMSRAETGRWTE 61 Query 66 AMLASGARLDFTDLPLATVDKHSTGGVGDKITLPLVPVVAACGGAVPQASGRGLGHTGGT 125 AM+ SG R+DF+DLPL TVDKHSTGGVGDKITLPL P+VAACG AVPQ SGRGLGHTGGT Sbjct 62 AMIESGGRMDFSDLPLPTVDKHSTGGVGDKITLPLAPLVAACGLAVPQLSGRGLGHTGGT 121 Query 126 LDKLESITGFTANLSNQRVREQLCD--VGAAIFAAG-QLAPADAKLYALRDITGTVESLP 182 LDKLE+I G+ A L+ + + L D +GA I AAG LAPAD KLYALRD+TGTVES+P Sbjct 122 LDKLEAIPGWRAELTATEMVDILSDPKIGAVICAAGANLAPADKKLYALRDVTGTVESIP 181 Query 183 LIASSIMSKKLAEGAGALVLDVKVGSGAFMRSPVQARELAHTMVELGAAHGVPTRALLTE 242 LIASSIMSKK+AEG GALVLDVKVGSGAFM+ ARELA TMVELG GV T AL+T Sbjct 182 LIASSIMSKKIAEGTGALVLDVKVGSGAFMKDLGDARELARTMVELGNDAGVRTSALITG 241 Query 243 MNCPLGRTVGNALEVAEALEVLAGGGPPDVVELTLRLAGEMLELAGIHGRDPAQTLRDGT 302 M+ PLG T GNALEV E++EVLAGGGP DVVELTL LA EML AGI G DPA L DGT Sbjct 242 MDTPLGLTAGNALEVRESVEVLAGGGPSDVVELTLVLAREMLSAAGIDGIDPADKLADGT 301 Query 303 AMDRFRRLVAAQGGDLSKPLPIGSHSETVTAGASGTMGDIDAMAVGLAAWRLGAGRSRPG 362 AMDR+R ++AAQGGD LP+ HS+ VTA G + +DAMAVG+AAW+LGAGR R G Sbjct 302 AMDRWRAMIAAQGGDPHATLPVARHSDVVTADRDGVLTRLDAMAVGIAAWKLGAGRERQG 361 Query 363 ARVQHGAGVRIHRRPGEPVVVGEPLFTLYTNAPERFGAARAELAGGWSI-RDSPPQVRPL 421 VQ GAG+ +H +PG+ V G+ L TL+T+ PERF AAR L GGWSI DS RPL Sbjct 362 EAVQAGAGIEMHAKPGDVVRAGQKLMTLHTDTPERFDAARRSLGGGWSIGTDSDTVSRPL 421 Query 422 IVDRIV 427 +++RIV Sbjct 422 LIERIV 427 >gi|226305534|ref|YP_002765494.1| pyrimidine nucleoside phosphorylase [Rhodococcus erythropolis PR4] gi|226184651|dbj|BAH32755.1| pyrimidine nucleoside phosphorylase [Rhodococcus erythropolis PR4] Length=431 Score = 520 bits (1338), Expect = 2e-145, Method: Compositional matrix adjust. Identities = 280/426 (66%), Positives = 324/426 (77%), Gaps = 4/426 (0%) Query 6 FDAPTVIRTKRDGGRLSDAAIDWVVKAYTDGRVADEQMSALLMAIVWRGMDRGEIARWTA 65 FDA ++I KRDG LS IDW+V+A+T+G V DEQMSAL MAI +RGM R E RWT Sbjct 2 FDAVSIIGAKRDGRELSGTEIDWIVQAFTEGVVGDEQMSALAMAIYFRGMSRAETGRWTE 61 Query 66 AMLASGARLDFTDLPLATVDKHSTGGVGDKITLPLVPVVAACGGAVPQASGRGLGHTGGT 125 AM+ SG R+DF+DLPL TVDKHSTGGVGDKITLPL P+VAACG AVPQ SGRGLGHTGGT Sbjct 62 AMIESGGRMDFSDLPLPTVDKHSTGGVGDKITLPLAPLVAACGLAVPQLSGRGLGHTGGT 121 Query 126 LDKLESITGFTANLSNQRVREQLCD--VGAAIFAAG-QLAPADAKLYALRDITGTVESLP 182 LDKLE+I G+ A L+ + + L D +GA I AAG LAPAD KLYALRD+TGTVES+P Sbjct 122 LDKLEAIPGWRAELTATEMVDILADPKIGAVICAAGANLAPADKKLYALRDVTGTVESIP 181 Query 183 LIASSIMSKKLAEGAGALVLDVKVGSGAFMRSPVQARELAHTMVELGAAHGVPTRALLTE 242 LIASSIMSKK+AEG GALVLDVKVGSGAFM+ ARELA TMVELG GV T AL+T Sbjct 182 LIASSIMSKKIAEGTGALVLDVKVGSGAFMKDLGDARELARTMVELGNDAGVRTSALITG 241 Query 243 MNCPLGRTVGNALEVAEALEVLAGGGPPDVVELTLRLAGEMLELAGIHGRDPAQTLRDGT 302 M+ PLG T GNALEV E++EVLAGGGP DVVELTL LA EML AGI G DPA L DGT Sbjct 242 MDTPLGLTAGNALEVRESVEVLAGGGPSDVVELTLVLAREMLSAAGIDGIDPADRLADGT 301 Query 303 AMDRFRRLVAAQGGDLSKPLPIGSHSETVTAGASGTMGDIDAMAVGLAAWRLGAGRSRPG 362 AMDR+R ++AAQGGD LP+ HS+ VTA G + +DAMAVG+AAW+LGAGR R G Sbjct 302 AMDRWRAMIAAQGGDPHATLPVARHSDVVTADRDGVLTRLDAMAVGIAAWKLGAGRERQG 361 Query 363 ARVQHGAGVRIHRRPGEPVVVGEPLFTLYTNAPERFGAARAELAGGWSI-RDSPPQVRPL 421 VQ GAG+ +H +PG+ V G+ L TL+T+ PERF AAR L GGWSI DS RPL Sbjct 362 EAVQAGAGIEMHAKPGDVVRAGQKLMTLHTDTPERFDAARRSLGGGWSIGADSDTVSRPL 421 Query 422 IVDRIV 427 +++RIV Sbjct 422 LIERIV 427 >gi|337767771|emb|CCB76482.1| Thymidine phosphorylase [Streptomyces cattleya NRRL 8057] Length=425 Score = 518 bits (1333), Expect = 9e-145, Method: Compositional matrix adjust. Identities = 278/424 (66%), Positives = 324/424 (77%), Gaps = 3/424 (0%) Query 6 FDAPTVIRTKRDGGRLSDAAIDWVVKAYTDGRVADEQMSALLMAIVWRGMDRGEIARWTA 65 D +VIRTKRD GRL+D IDWV+ AYT G VADEQMSAL MAI+ GMDR EIARWTA Sbjct 1 MDVISVIRTKRDRGRLTDEQIDWVIDAYTRGEVADEQMSALAMAILLNGMDRAEIARWTA 60 Query 66 AMLASGARLDFTDLPLATVDKHSTGGVGDKITLPLVPVVAACGGAVPQASGRGLGHTGGT 125 AM+ASG R++F+ LP T DKHSTGGVGDKITLPL P+VAACG AVPQ SGRGLGHTGGT Sbjct 61 AMIASGERMEFSSLPRPTADKHSTGGVGDKITLPLAPLVAACGAAVPQLSGRGLGHTGGT 120 Query 126 LDKLESITGFTANLSNQRVREQLCDVGAAIFAAGQ-LAPADAKLYALRDITGTVESLPLI 184 LDKLESI G+ A LSN + L DVGA I AAG LAPAD KLYALRD+TGTVE++PLI Sbjct 121 LDKLESIPGWRALLSNDEMMGVLRDVGAVICAAGDGLAPADKKLYALRDVTGTVEAIPLI 180 Query 185 ASSIMSKKLAEGAGALVLDVKVGSGAFMRSPVQARELAHTMVELGAAHGVPTRALLTEMN 244 ASSIMSKK+AEG G+LVLDVKVGSGAFM++ ARELA TMV LG HGV T ALLT+M+ Sbjct 181 ASSIMSKKIAEGTGSLVLDVKVGSGAFMKTVADARELATTMVGLGTDHGVRTVALLTDMS 240 Query 245 CPLGRTVGNALEVAEALEVLAGGGPPDVVELTLRLAGEMLELAGIHGRDPAQTLRDGTAM 304 PLG T GNALEV E++EVLAGGGP DVVELTL LA EML+ AG+ DPA+ LRDGTAM Sbjct 241 TPLGLTAGNALEVRESVEVLAGGGPADVVELTLALAREMLDAAGLPDADPAKALRDGTAM 300 Query 305 DRFRRLVAAQGGDLSKPLPIGSHSETVTAGASGTMGDIDAMAVGLAAWRLGAGRSRPGAR 364 D +RR+++AQGGD PLP+ VTA A+G + +DA AVG+AAWRLGAGRSR Sbjct 301 DHWRRMISAQGGDPDAPLPVARERHVVTAPATGVLTGLDAYAVGVAAWRLGAGRSRKEDP 360 Query 365 VQHGAGVRIHRRPGEPVVVGEPLFTLYTNAPERFGAARAELAGGWSIRD--SPPQVRPLI 422 VQ GAGV +H +PG+ V G PL TL+T+ PERF A L G ++ +P RP++ Sbjct 361 VQAGAGVELHAKPGDQVTAGRPLLTLHTDTPERFDYALQALDGAVTVAPAGTPFTPRPIV 420 Query 423 VDRI 426 ++RI Sbjct 421 LERI 424 >gi|297158060|gb|ADI07772.1| thymidine phosphorylase [Streptomyces bingchenggensis BCW-1] Length=426 Score = 513 bits (1321), Expect = 3e-143, Method: Compositional matrix adjust. Identities = 278/426 (66%), Positives = 321/426 (76%), Gaps = 7/426 (1%) Query 6 FDAPTVIRTKRDGGRLSDAAIDWVVKAYTDGRVADEQMSALLMAIVWRGMDRGEIARWTA 65 DA TVIR KRDGGRL+DA IDW++ AYT G VA EQMSAL MAI GMDR EIARWTA Sbjct 1 MDAITVIRAKRDGGRLTDAQIDWIIDAYTRGEVAHEQMSALAMAIYLNGMDRAEIARWTA 60 Query 66 AMLASGARLDFTDLPLATVDKHSTGGVGDKITLPLVPVVAACGGAVPQASGRGLGHTGGT 125 AM+ASG R+DF+ L T DKHSTGGVGDKITLPL P+VAACG AVPQ SGRGLGHTGGT Sbjct 61 AMIASGERMDFSSLARPTADKHSTGGVGDKITLPLAPLVAACGAAVPQLSGRGLGHTGGT 120 Query 126 LDKLESITGFTANLSNQRVREQLCDVGAAIFAAGQ-LAPADAKLYALRDITGTVESLPLI 184 LDKLESI G+ A LS + + L DVG+ I AAG+ LAPAD KLYALRD+TGTVES+PLI Sbjct 121 LDKLESIPGWRARLSGEEMLRVLEDVGSVICAAGEGLAPADRKLYALRDVTGTVESIPLI 180 Query 185 ASSIMSKKLAEGAGALVLDVKVGSGAFMRSPVQARELAHTMVELGAAHGVPTRALLTEMN 244 ASSIMSKK+AEG G+LVLDVKVGSGAFM+ ARELA TMV LG HGV T ALLT M Sbjct 181 ASSIMSKKIAEGTGSLVLDVKVGSGAFMKDLASARELAATMVGLGTDHGVRTVALLTGMA 240 Query 245 CPLGRTVGNALEVAEALEVLAGGGPPDVVELTLRLAGEMLELAGIHGRDPAQTLRDGTAM 304 PLGRT GNALEV E++EVLAGGGP DVVELTL LA EML+ AG+ DPA+ L DG+AM Sbjct 241 TPLGRTAGNALEVRESVEVLAGGGPADVVELTLALAREMLDAAGLPDADPAKALADGSAM 300 Query 305 DRFRRLVAAQGGDLSKPLPIGSHSETVTAGASGTMGDIDAMAVGLAAWRLGAGRSRPGAR 364 D +RR++AAQGGD PLP+ VTA ++G + +DA AVG+ AWRLGAGR+R Sbjct 301 DHWRRMIAAQGGDPDAPLPVAREQHVVTAESTGVLTGLDAYAVGVVAWRLGAGRARKEDP 360 Query 365 VQHGAGVRIHRRPGEPVVVGEPLFTLYTNAPERFGAARAELAGGWSIRDSPPQV----RP 420 VQ GAGV IH +PG+ V G+PL TL+T+ PE+F A LAG S +PP P Sbjct 361 VQAGAGVEIHAKPGDAVRAGDPLLTLHTDTPEKFDYALEALAGAVSY--APPGTEFTPEP 418 Query 421 LIVDRI 426 +++DRI Sbjct 419 IVLDRI 424 >gi|345015794|ref|YP_004818148.1| pyrimidine-nucleoside phosphorylase [Streptomyces violaceusniger Tu 4113] gi|344042143|gb|AEM87868.1| pyrimidine-nucleoside phosphorylase [Streptomyces violaceusniger Tu 4113] Length=425 Score = 511 bits (1317), Expect = 7e-143, Method: Compositional matrix adjust. Identities = 275/424 (65%), Positives = 319/424 (76%), Gaps = 3/424 (0%) Query 6 FDAPTVIRTKRDGGRLSDAAIDWVVKAYTDGRVADEQMSALLMAIVWRGMDRGEIARWTA 65 DA +VIR KRDG RL+DA IDW++ AYT G VADEQMSAL MAI GMDR EIARWTA Sbjct 1 MDAISVIRAKRDGTRLTDAQIDWIIDAYTRGEVADEQMSALAMAIFLNGMDRAEIARWTA 60 Query 66 AMLASGARLDFTDLPLATVDKHSTGGVGDKITLPLVPVVAACGGAVPQASGRGLGHTGGT 125 AM+ASG R+DF+ LP T DKHSTGGVGDKITLPL P+VAACG AVPQ SGRGLGHTGGT Sbjct 61 AMIASGERMDFSSLPRPTADKHSTGGVGDKITLPLAPLVAACGAAVPQLSGRGLGHTGGT 120 Query 126 LDKLESITGFTANLSNQRVREQLCDVGAAIFAAGQ-LAPADAKLYALRDITGTVESLPLI 184 LDKLESI G+ A LSN+ + L DVG I AAG+ LAPAD KLYALRD+TGTVES+PLI Sbjct 121 LDKLESIPGWRAQLSNEDMLAVLRDVGPVICAAGEGLAPADKKLYALRDVTGTVESIPLI 180 Query 185 ASSIMSKKLAEGAGALVLDVKVGSGAFMRSPVQARELAHTMVELGAAHGVPTRALLTEMN 244 ASSIMSKK+AEG G+LVLDVKVGSGAFM+ ARELA TMV LG HGV T ALLT+M+ Sbjct 181 ASSIMSKKIAEGTGSLVLDVKVGSGAFMKDIDSARELATTMVGLGNDHGVRTTALLTDMS 240 Query 245 CPLGRTVGNALEVAEALEVLAGGGPPDVVELTLRLAGEMLELAGIHGRDPAQTLRDGTAM 304 PLG T GNALEV E++EVLAGGGP DVVELTL LA EML+ AG+ DPA+ L DGTAM Sbjct 241 TPLGLTAGNALEVRESVEVLAGGGPADVVELTLALAREMLDAAGLPDADPAKALADGTAM 300 Query 305 DRFRRLVAAQGGDLSKPLPIGSHSETVTAGASGTMGDIDAMAVGLAAWRLGAGRSRPGAR 364 D +RR++AAQGGD PLP VTA A G + +DA AVGLAAWRLGAGR+R Sbjct 301 DHWRRMIAAQGGDPDAPLPTAREHHVVTATADGVLTRLDAYAVGLAAWRLGAGRARKEDP 360 Query 365 VQHGAGVRIHRRPGEPVVVGEPLFTLYTNAPERFGAARAEL--AGGWSIRDSPPQVRPLI 422 VQ GAGV +H +PG+ V G+PL TL+T+ P F A L A ++ ++ P++ Sbjct 361 VQAGAGVELHAKPGDRVTTGQPLLTLHTDTPSAFAYALEALKDAVTYAPHNTDFTTTPIV 420 Query 423 VDRI 426 ++RI Sbjct 421 LERI 424 >gi|326334079|ref|ZP_08200307.1| thymidine phosphorylase [Nocardioidaceae bacterium Broad-1] gi|325948130|gb|EGD40242.1| thymidine phosphorylase [Nocardioidaceae bacterium Broad-1] Length=427 Score = 510 bits (1314), Expect = 1e-142, Method: Compositional matrix adjust. Identities = 277/423 (66%), Positives = 322/423 (77%), Gaps = 2/423 (0%) Query 6 FDAPTVIRTKRDGGRLSDAAIDWVVKAYTDGRVADEQMSALLMAIVWRGMDRGEIARWTA 65 DA VI KRDGG LSD+ IDW++ AYT G VA+EQMSAL MAI+ GM R EIARWTA Sbjct 4 HDAVEVILAKRDGGELSDSQIDWMIAAYTRGVVAEEQMSALNMAILLNGMSRREIARWTA 63 Query 66 AMLASGARLDFTDLPLATVDKHSTGGVGDKITLPLVPVVAACGGAVPQASGRGLGHTGGT 125 AM+ASG R+ F L T DKHSTGGVGDKITLPL P+VAACG AVPQ SGRGLGHTGGT Sbjct 64 AMIASGERMSFDSLDRPTADKHSTGGVGDKITLPLAPLVAACGVAVPQLSGRGLGHTGGT 123 Query 126 LDKLESITGFTANLSNQRVREQLCDVGAAIFAAGQ-LAPADAKLYALRDITGTVESLPLI 184 LDKLESI G+ A+LSN+ + QL VGA I AAG+ LAPAD KLYALRD+TGTVES+PLI Sbjct 124 LDKLESIPGWRASLSNEEMLAQLGSVGAVICAAGEGLAPADRKLYALRDVTGTVESIPLI 183 Query 185 ASSIMSKKLAEGAGALVLDVKVGSGAFMRSPVQARELAHTMVELGAAHGVPTRALLTEMN 244 ASSIMSKK+AEG GALVLDVKVG+GAFM++ A+ELA TMV+LG GV T AL+T+M Sbjct 184 ASSIMSKKIAEGTGALVLDVKVGAGAFMKTLDSAQELARTMVDLGTDAGVNTVALVTDMA 243 Query 245 CPLGRTVGNALEVAEALEVLAGGGPPDVVELTLRLAGEMLELAGIHGRDPAQTLRDGTAM 304 PLG T GNA+EVAE++EVLAGGGP DVVELT+ LA EML AG+ G DPA+ L G AM Sbjct 244 TPLGLTAGNAIEVAESVEVLAGGGPADVVELTVALAREMLSAAGVSGPDPAEVLASGKAM 303 Query 305 DRFRRLVAAQGGDLSKPLPIGSHSETVTAGASGTMGDIDAMAVGLAAWRLGAGRSRPGAR 364 D +R +++AQGGD S PLP+ + VTA +SG + +DAMAVGLAAWRLGAGR R Sbjct 304 DAWRAMISAQGGDPSAPLPVARETHVVTAPSSGVLTRLDAMAVGLAAWRLGAGRERKEDA 363 Query 365 VQHGAGVRIHRRPGEPVVVGEPLFTLYTNAPERFGAARAELAGGWSIRD-SPPQVRPLIV 423 VQ GAGV H RPG+ V G PLFTL+T+ PERF A A L GG+ I D + + PLI+ Sbjct 364 VQAGAGVTWHARPGDSVTAGAPLFTLHTDTPERFDRALAALEGGYEIGDGAAYEATPLIL 423 Query 424 DRI 426 DRI Sbjct 424 DRI 426 >gi|291437641|ref|ZP_06577031.1| thymidine phosphorylase [Streptomyces ghanaensis ATCC 14672] gi|291340536|gb|EFE67492.1| thymidine phosphorylase [Streptomyces ghanaensis ATCC 14672] Length=427 Score = 508 bits (1309), Expect = 5e-142, Method: Compositional matrix adjust. Identities = 275/428 (65%), Positives = 319/428 (75%), Gaps = 7/428 (1%) Query 4 FAFDAPTVIRTKRDGGRLSDAAIDWVVKAYTDGRVADEQMSALLMAIVWRGMDRGEIARW 63 A DA +VIRTKRD G LSD IDWV+ AYT G VADEQMSAL MAI+ GM+R EIARW Sbjct 1 MAMDAISVIRTKRDRGELSDEQIDWVIDAYTRGEVADEQMSALAMAILLNGMNRSEIARW 60 Query 64 TAAMLASGARLDFTDLPLATVDKHSTGGVGDKITLPLVPVVAACGGAVPQASGRGLGHTG 123 TAAM+ASG R+DF+ L T DKHSTGGVGDKITLPL P+VAACG AVPQ SGRGLGHTG Sbjct 61 TAAMIASGERMDFSSLSRPTTDKHSTGGVGDKITLPLAPLVAACGAAVPQLSGRGLGHTG 120 Query 124 GTLDKLESITGFTANLSNQRVREQLCDVGAAIFAAGQ-LAPADAKLYALRDITGTVESLP 182 GTLDKLESI G+ A LSN+ + L D GA I AAG LAPAD KLYALRD+TGTVE++P Sbjct 121 GTLDKLESIPGWRALLSNEEMLSVLDDAGAVICAAGDGLAPADKKLYALRDVTGTVEAIP 180 Query 183 LIASSIMSKKLAEGAGALVLDVKVGSGAFMRSPVQARELAHTMVELGAAHGVPTRALLTE 242 LIASSIMSKK+AEG GALVLDVKVGSGAFM++ ARELA TMV LG HGV T ALLT+ Sbjct 181 LIASSIMSKKIAEGTGALVLDVKVGSGAFMKTIEDARELARTMVGLGTDHGVRTVALLTD 240 Query 243 MNCPLGRTVGNALEVAEALEVLAGGGPPDVVELTLRLAGEMLELAGIHGRDPAQTLRDGT 302 M PLG T GNALEV E++EVLAGGGP DVVELTL LA EML+ AG+ DPA+ L DG+ Sbjct 241 MATPLGLTAGNALEVRESVEVLAGGGPADVVELTLALAREMLDAAGLKDADPAKALADGS 300 Query 303 AMDRFRRLVAAQGGDLSKPLPIGSHSETVTAGASGTMGDIDAMAVGLAAWRLGAGRSRPG 362 AMD +RR++ AQGGD PLP V A ASG + +DA VG+AAWRLGAGR+R Sbjct 301 AMDVWRRMITAQGGDPDAPLPTAREQHVVKAPASGVLTRLDAYDVGVAAWRLGAGRARKE 360 Query 363 ARVQHGAGVRIHRRPGEPVVVGEPLFTLYTNAPERFGAARAELAGGWSI----RDSPPQV 418 VQ GAGV +H +PG+PV G+PL TL+T+ P+RF A + G + I D P Sbjct 361 DPVQAGAGVELHAKPGDPVTEGQPLLTLHTDTPDRFAYALRAIEGSYDIAAPGTDFTPS- 419 Query 419 RPLIVDRI 426 P++++RI Sbjct 420 -PVVLERI 426 >gi|290957952|ref|YP_003489134.1| thymidine phosphorylase [Streptomyces scabiei 87.22] gi|260647478|emb|CBG70583.1| thymidine phosphorylase [Streptomyces scabiei 87.22] Length=433 Score = 508 bits (1308), Expect = 7e-142, Method: Compositional matrix adjust. Identities = 271/428 (64%), Positives = 321/428 (75%), Gaps = 3/428 (0%) Query 2 TDFAFDAPTVIRTKRDGGRLSDAAIDWVVKAYTDGRVADEQMSALLMAIVWRGMDRGEIA 61 T + DA +VIRTKRD G LSD IDWV+ AYT G VAD QM+AL MAI+ GMDR EIA Sbjct 5 TTMSMDAISVIRTKRDRGELSDEQIDWVIDAYTRGEVADYQMAALNMAILLNGMDRREIA 64 Query 62 RWTAAMLASGARLDFTDLPLATVDKHSTGGVGDKITLPLVPVVAACGGAVPQASGRGLGH 121 RWTAAM+ASG R+DF+ L T DKHSTGGVGDKITLPL P+VAACG AVPQ SGRGLGH Sbjct 65 RWTAAMIASGERMDFSSLSRPTADKHSTGGVGDKITLPLAPLVAACGAAVPQLSGRGLGH 124 Query 122 TGGTLDKLESITGFTANLSNQRVREQLCDVGAAIFAAGQ-LAPADAKLYALRDITGTVES 180 TGGTLDKLESI G+ A LSN+ + L +VGA I AAG LAPAD KLYALRD+TGTVE+ Sbjct 125 TGGTLDKLESIPGWRALLSNEEMLNVLDEVGAVICAAGDGLAPADKKLYALRDVTGTVEA 184 Query 181 LPLIASSIMSKKLAEGAGALVLDVKVGSGAFMRSPVQARELAHTMVELGAAHGVPTRALL 240 +PLIASSIMSKK+AEG G+LVLDVKVGSGAFM++ ARELA TMV LG HGV T ALL Sbjct 185 IPLIASSIMSKKIAEGTGSLVLDVKVGSGAFMKTLEDARELASTMVGLGTDHGVKTVALL 244 Query 241 TEMNCPLGRTVGNALEVAEALEVLAGGGPPDVVELTLRLAGEMLELAGIHGRDPAQTLRD 300 T+M+ PLG T GNALEV E++EVLAGGGP DVVELT+ LA EML+ AG+ DPA+ L D Sbjct 245 TDMSTPLGLTAGNALEVRESVEVLAGGGPADVVELTIALAREMLDAAGVKDADPAKALAD 304 Query 301 GTAMDRFRRLVAAQGGDLSKPLPIGSHSETVTAGASGTMGDIDAMAVGLAAWRLGAGRSR 360 G+AMD +RR++AAQGGD PLP V A ASG + +DA +G+AAWRLGAGR+R Sbjct 305 GSAMDAWRRMIAAQGGDPDAPLPTSREQHVVKAAASGVLTRLDAYDIGIAAWRLGAGRAR 364 Query 361 PGARVQHGAGVRIHRRPGEPVVVGEPLFTLYTNAPERFGAARAELAGGWSI--RDSPPQV 418 VQ AGV +H +PG+ V G+PL TL+T+ PERF A +AG + I + + Sbjct 365 KEDPVQAAAGVELHAKPGDTVTEGQPLLTLHTDTPERFDYALEAVAGSYDIGAPGTAYEP 424 Query 419 RPLIVDRI 426 P+++DRI Sbjct 425 TPIVLDRI 432 >gi|302544708|ref|ZP_07297050.1| pyrimidine-nucleoside phosphorylase [Streptomyces hygroscopicus ATCC 53653] gi|302462326|gb|EFL25419.1| pyrimidine-nucleoside phosphorylase [Streptomyces himastatinicus ATCC 53653] Length=425 Score = 506 bits (1304), Expect = 2e-141, Method: Compositional matrix adjust. Identities = 273/427 (64%), Positives = 318/427 (75%), Gaps = 9/427 (2%) Query 6 FDAPTVIRTKRDGGRLSDAAIDWVVKAYTDGRVADEQMSALLMAIVWRGMDRGEIARWTA 65 DA +VIR KRDGGRLSDA IDW++ AYT G VA EQMSAL MAI GMDR EIARWTA Sbjct 1 MDAISVIRAKRDGGRLSDAQIDWIIDAYTRGEVAHEQMSALAMAIFLTGMDRAEIARWTA 60 Query 66 AMLASGARLDFTDLPLATVDKHSTGGVGDKITLPLVPVVAACGGAVPQASGRGLGHTGGT 125 AM+ASG R+DF+ LP T DKHSTGGVGDKITLPL P+VAACG AVPQ SGRGLGHTGGT Sbjct 61 AMIASGERMDFSSLPRPTADKHSTGGVGDKITLPLAPLVAACGAAVPQLSGRGLGHTGGT 120 Query 126 LDKLESITGFTANLSNQRVREQLCDVGAAIFAAGQ-LAPADAKLYALRDITGTVESLPLI 184 LDKLESI G+ A+LSN + + L VG+ I AAG LAPAD KLYALRD+TGTVES+PLI Sbjct 121 LDKLESIPGWRASLSNDDMLDVLRSVGSVICAAGDGLAPADKKLYALRDVTGTVESIPLI 180 Query 185 ASSIMSKKLAEGAGALVLDVKVGSGAFMRSPVQARELAHTMVELGAAHGVPTRALLTEMN 244 ASSIMSKK+AEG G+LVLDVKVGSGAFM+ ARELA TMV LG HGV T ALLT+M Sbjct 181 ASSIMSKKIAEGTGSLVLDVKVGSGAFMKDIDAARELATTMVGLGTDHGVRTTALLTDMA 240 Query 245 CPLGRTVGNALEVAEALEVLAGGGPPDVVELTLRLAGEMLELAGIHGRDPAQTLRDGTAM 304 PLG T GNALEV E++EVLAGGGP DVVELTL LA EML+ AG+ DPA+ L DGTAM Sbjct 241 TPLGLTAGNALEVRESVEVLAGGGPADVVELTLALAREMLDAAGLPDADPAKALADGTAM 300 Query 305 DRFRRLVAAQGGDLSKPLPIGSHSETVTAGASGTMGDIDAMAVGLAAWRLGAGRSRPGAR 364 D +RR++ AQGGD LP+ VTA ++G + +DA AVG+AAWRLGAGR+R Sbjct 301 DHWRRMITAQGGDADASLPVAREQHIVTAESTGVLTRLDAYAVGVAAWRLGAGRARKEDP 360 Query 365 VQHGAGVRIHRRPGEPVVVGEPLFTLYTNAPERFGAARAELAGGWSIRDSPPQ-----VR 419 VQ GAG+ IH +PG+ V G+PL TL+T+ P F A L G D P+ + Sbjct 361 VQAGAGIEIHAKPGDQVTAGQPLLTLHTDTPAAFTYALEALDGA---TDYAPEGTAFTSK 417 Query 420 PLIVDRI 426 P++++RI Sbjct 418 PIVLERI 424 >gi|318060158|ref|ZP_07978881.1| thymidine phosphorylase [Streptomyces sp. SA3_actG] gi|318075407|ref|ZP_07982739.1| thymidine phosphorylase [Streptomyces sp. SA3_actF] Length=426 Score = 505 bits (1301), Expect = 5e-141, Method: Compositional matrix adjust. Identities = 268/423 (64%), Positives = 320/423 (76%), Gaps = 2/423 (0%) Query 6 FDAPTVIRTKRDGGRLSDAAIDWVVKAYTDGRVADEQMSALLMAIVWRGMDRGEIARWTA 65 D +VIRTKRD G LS+A IDWVV AYT G VADEQMSAL MAI+ GM RGEIARWTA Sbjct 1 MDVISVIRTKRDRGELSEAQIDWVVDAYTRGAVADEQMSALAMAILLNGMTRGEIARWTA 60 Query 66 AMLASGARLDFTDLPLATVDKHSTGGVGDKITLPLVPVVAACGGAVPQASGRGLGHTGGT 125 AM+ASG R+DF+ L T DKHSTGGVGDKITLPL P+VAACG AVPQ SGRGLGHTGGT Sbjct 61 AMIASGERMDFSSLSRPTADKHSTGGVGDKITLPLAPLVAACGAAVPQLSGRGLGHTGGT 120 Query 126 LDKLESITGFTANLSNQRVREQLCDVGAAIFAAGQ-LAPADAKLYALRDITGTVESLPLI 184 LDKLE++ G+ A+LSN + + L GA I AAG LAPAD KLYALRD+TGTVE++PLI Sbjct 121 LDKLEAVPGWRASLSNAELMDVLDSTGAVICAAGDGLAPADKKLYALRDVTGTVEAIPLI 180 Query 185 ASSIMSKKLAEGAGALVLDVKVGSGAFMRSPVQARELAHTMVELGAAHGVPTRALLTEMN 244 ASSIMSKK+AEG G+LVLDVK GSGAFM++ ARELA TMV LG HGV T ALLT+M+ Sbjct 181 ASSIMSKKIAEGTGSLVLDVKCGSGAFMKNAADARELAETMVGLGTDHGVRTVALLTDMS 240 Query 245 CPLGRTVGNALEVAEALEVLAGGGPPDVVELTLRLAGEMLELAGIHGRDPAQTLRDGTAM 304 PLG T GNALEV E++EVLAGGGP DVVELTL LA EML+ AG+ DPA+ L DG+AM Sbjct 241 TPLGLTAGNALEVRESVEVLAGGGPADVVELTLALAREMLDGAGLTDADPAKALADGSAM 300 Query 305 DRFRRLVAAQGGDLSKPLPIGSHSETVTAGASGTMGDIDAMAVGLAAWRLGAGRSRPGAR 364 D +RR++AAQGGD LP+ + VTA G + +DA +G+AAWRLGAGR+R Sbjct 301 DVWRRMIAAQGGDPDADLPVARETHVVTAPRDGVLTRLDAYDIGVAAWRLGAGRARKEDP 360 Query 365 VQHGAGVRIHRRPGEPVVVGEPLFTLYTNAPERFGAARAELAGGWSIRDSPP-QVRPLIV 423 VQ GAGV +H +PGEPV G+PL TL+T+ P+RF A + G + I ++ RP+++ Sbjct 361 VQAGAGVELHAKPGEPVRAGQPLLTLHTDTPDRFAYALESVEGSYDIEETGGLMARPIVL 420 Query 424 DRI 426 DR+ Sbjct 421 DRV 423 >gi|297562172|ref|YP_003681146.1| pyrimidine-nucleoside phosphorylase [Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111] gi|296846620|gb|ADH68640.1| pyrimidine-nucleoside phosphorylase [Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111] Length=431 Score = 505 bits (1300), Expect = 6e-141, Method: Compositional matrix adjust. Identities = 276/430 (65%), Positives = 319/430 (75%), Gaps = 9/430 (2%) Query 6 FDAPTVIRTKRDGGRLSDAAIDWVVKAYTDGRVADEQMSALLMAIVWRGMDRGEIARWTA 65 D +IR KRDGG LS IDWV+ AYT G VA+EQMSAL MAI RGMDR E++RWT Sbjct 1 MDVIEIIRAKRDGGELSPGQIDWVIDAYTRGEVAEEQMSALAMAIFLRGMDRAEVSRWTE 60 Query 66 AMLASGARLDFTDLPLATVDKHSTGGVGDKITLPLVPVVAACGGAVPQASGRGLGHTGGT 125 AMLASG RLDF+DL T DKHSTGGVGDKITLPL P VAACG AVPQ SGRGLGHTGGT Sbjct 61 AMLASGERLDFSDLARPTTDKHSTGGVGDKITLPLTPTVAACGAAVPQLSGRGLGHTGGT 120 Query 126 LDKLESITGFTANLSNQRVREQLCDVGAAIFAAGQ-LAPADAKLYALRDITGTVESLPLI 184 LDKLESI G+ A+LS +RE L G I AAG LAPAD KLYALRD+TGTVES+PLI Sbjct 121 LDKLESIPGWRASLSTGEMREVLDSTGGVICAAGSGLAPADRKLYALRDVTGTVESIPLI 180 Query 185 ASSIMSKKLAEGAGALVLDVKVGSGAFMRSPVQARELAHTMVELGAAHGVPTRALLTEMN 244 A+SIMSKKLAEG GALVLDVKVGSGAFM+ ARELA TMV++G HGV T ALLT+M+ Sbjct 181 AASIMSKKLAEGTGALVLDVKVGSGAFMKDADSARELARTMVDIGNDHGVRTVALLTDMS 240 Query 245 CPLGRTVGNALEVAEALEVLAGGGPPDVVELTLRLAGEMLELAGI---HG--RDPAQTLR 299 PLGR VGNALEVAE++EVL+GGGP DVVELT+ LA EML AG+ G +DPA+ LR Sbjct 241 VPLGRQVGNALEVAESVEVLSGGGPADVVELTVALAREMLAAAGLVPGEGGVKDPAEALR 300 Query 300 DGTAMDRFRRLVAAQGGDLSKPLPIGSHSETVTAGASGTMGDIDAMAVGLAAWRLGAGRS 359 DG+A++ ++RLV AQGGD PLP+ + V A ASGT+ +DA VGLAAWRLGAGR+ Sbjct 301 DGSALESWKRLVRAQGGDPDAPLPVAAERRVVLAPASGTVTRLDAYQVGLAAWRLGAGRA 360 Query 360 RPGARVQHGAGVRIHRRPGEPVVVGEPLFTLYTNAPERFGAARAELAGGWSIR---DSPP 416 R V GAGV +H +PGE V GEPLFTL+ + ERF A L G + I + Sbjct 361 RKEDAVSFGAGVTLHAKPGESVQAGEPLFTLHADEAERFERAAEALEGAFDIEPEGGAGY 420 Query 417 QVRPLIVDRI 426 + RPL++DRI Sbjct 421 EARPLVIDRI 430 >gi|302519472|ref|ZP_07271814.1| thymidine phosphorylase [Streptomyces sp. SPB78] gi|302428367|gb|EFL00183.1| thymidine phosphorylase [Streptomyces sp. SPB78] Length=426 Score = 505 bits (1300), Expect = 7e-141, Method: Compositional matrix adjust. Identities = 268/423 (64%), Positives = 320/423 (76%), Gaps = 2/423 (0%) Query 6 FDAPTVIRTKRDGGRLSDAAIDWVVKAYTDGRVADEQMSALLMAIVWRGMDRGEIARWTA 65 D +VIRTKRD G LS+A IDWVV AYT G VADEQMSAL MAI+ GM RGEIARWTA Sbjct 1 MDVISVIRTKRDRGELSEAQIDWVVDAYTRGAVADEQMSALAMAILLNGMTRGEIARWTA 60 Query 66 AMLASGARLDFTDLPLATVDKHSTGGVGDKITLPLVPVVAACGGAVPQASGRGLGHTGGT 125 AM+ASG R+DF+ L T DKHSTGGVGDKITLPL P+VAACG AVPQ SGRGLGHTGGT Sbjct 61 AMIASGERMDFSSLSRPTADKHSTGGVGDKITLPLAPLVAACGAAVPQLSGRGLGHTGGT 120 Query 126 LDKLESITGFTANLSNQRVREQLCDVGAAIFAAGQ-LAPADAKLYALRDITGTVESLPLI 184 LDKLE++ G+ A+LSN + + L GA I AAG LAPAD KLYALRD+TGTVE++PLI Sbjct 121 LDKLEAVPGWRASLSNAELMDVLDSTGAVICAAGDGLAPADKKLYALRDVTGTVEAIPLI 180 Query 185 ASSIMSKKLAEGAGALVLDVKVGSGAFMRSPVQARELAHTMVELGAAHGVPTRALLTEMN 244 ASSIMSKK+AEG G+LVLDVK GSGAFM++ ARELA TMV LG HGV T ALLT+M+ Sbjct 181 ASSIMSKKIAEGTGSLVLDVKCGSGAFMKNAADARELAETMVGLGTDHGVRTVALLTDMS 240 Query 245 CPLGRTVGNALEVAEALEVLAGGGPPDVVELTLRLAGEMLELAGIHGRDPAQTLRDGTAM 304 PLG T GNALEV E++EVLAGGGP DVVELTL LA EML+ AG+ DPA+ L DG+AM Sbjct 241 TPLGLTAGNALEVRESVEVLAGGGPADVVELTLALAREMLDGAGLTDADPAKALADGSAM 300 Query 305 DRFRRLVAAQGGDLSKPLPIGSHSETVTAGASGTMGDIDAMAVGLAAWRLGAGRSRPGAR 364 D +RR++AAQGGD LP+ + VTA G + +DA +G+AAWRLGAGR+R Sbjct 301 DVWRRMIAAQGGDPDADLPVARETHVVTAPRDGVLTRLDAYDIGVAAWRLGAGRARKEDP 360 Query 365 VQHGAGVRIHRRPGEPVVVGEPLFTLYTNAPERFGAARAELAGGWSIRDSPP-QVRPLIV 423 VQ GAGV +H +PGEPV G+PL TL+T+ P+RF A + G + I ++ RP+++ Sbjct 361 VQAGAGVELHAKPGEPVRAGQPLLTLHTDTPDRFAYALESVEGSYGIEETGGLMARPIVL 420 Query 424 DRI 426 DR+ Sbjct 421 DRV 423 >gi|291451662|ref|ZP_06591052.1| thymidine phosphorylase [Streptomyces albus J1074] gi|291354611|gb|EFE81513.1| thymidine phosphorylase [Streptomyces albus J1074] Length=425 Score = 504 bits (1298), Expect = 1e-140, Method: Compositional matrix adjust. Identities = 272/428 (64%), Positives = 316/428 (74%), Gaps = 11/428 (2%) Query 6 FDAPTVIRTKRDGGRLSDAAIDWVVKAYTDGRVADEQMSALLMAIVWRGMDRGEIARWTA 65 D +VIR KRD L+DA IDW V AYT G VADEQMSAL MAI+ GMDR EIARWTA Sbjct 1 MDVISVIRAKRDRIPLTDAQIDWTVDAYTRGAVADEQMSALAMAILLNGMDRREIARWTA 60 Query 66 AMLASGARLDFTDLPLATVDKHSTGGVGDKITLPLVPVVAACGGAVPQASGRGLGHTGGT 125 AM+ASG RLDF+ L T DKHSTGGVGDKITLPL P+VAACG AVPQ SGRGLGHTGGT Sbjct 61 AMIASGERLDFSSLARPTADKHSTGGVGDKITLPLAPLVAACGAAVPQLSGRGLGHTGGT 120 Query 126 LDKLESITGFTANLSNQRVREQLCDVGAAIFAAGQ-LAPADAKLYALRDITGTVESLPLI 184 LDKLESI G+ A+LSN + + L GA I AAG LAPAD KLYALRD+TGTVE++PLI Sbjct 121 LDKLESIPGWRASLSNAELLDVLASTGAVICAAGDGLAPADKKLYALRDVTGTVEAIPLI 180 Query 185 ASSIMSKKLAEGAGALVLDVKVGSGAFMRSPVQARELAHTMVELGAAHGVPTRALLTEMN 244 ASSIMSKK+AEG G+LVLDVK G+GAFM++ ARELA TMV LG HGV T ALLT M+ Sbjct 181 ASSIMSKKIAEGTGSLVLDVKCGTGAFMKTVEDARELAETMVSLGTDHGVKTVALLTGMS 240 Query 245 CPLGRTVGNALEVAEALEVLAGGGPPDVVELTLRLAGEMLELAGIHGRDPAQTLRDGTAM 304 PLG T GNALEV E++EVLAGGGP DVVELTL LA +MLE AGIH DPA+ L DG+AM Sbjct 241 TPLGLTAGNALEVRESVEVLAGGGPADVVELTLALARDMLEAAGIHDADPAKKLVDGSAM 300 Query 305 DRFRRLVAAQGGDLSKPLPIGSHSETVTAGASGTMGDIDAMAVGLAAWRLGAGRSRPGAR 364 D +RR+++AQGGD PLP H+ TVTA A+G + +DA VG+AAWRLGAGR+R Sbjct 301 DVWRRMISAQGGDPDAPLPTARHTHTVTAPATGVLSRLDAYDVGVAAWRLGAGRARKEDP 360 Query 365 VQHGAGVRIHRRPGEPVVVGEPLFTLYTNAPERFGAARAELAGGWSIR------DSPPQV 418 VQ AG+ +H +PG+ V G PL TL+T+ ERF A L W I D+P Sbjct 361 VQAAAGIELHAKPGDTVTEGAPLLTLHTDTDERFAGALDALGSAWDIAAPGTTVDTP--- 417 Query 419 RPLIVDRI 426 P+++DRI Sbjct 418 -PIVLDRI 424 >gi|333026699|ref|ZP_08454763.1| putative thymidine phosphorylase [Streptomyces sp. Tu6071] gi|332746551|gb|EGJ76992.1| putative thymidine phosphorylase [Streptomyces sp. Tu6071] Length=426 Score = 503 bits (1296), Expect = 2e-140, Method: Compositional matrix adjust. Identities = 268/423 (64%), Positives = 319/423 (76%), Gaps = 2/423 (0%) Query 6 FDAPTVIRTKRDGGRLSDAAIDWVVKAYTDGRVADEQMSALLMAIVWRGMDRGEIARWTA 65 D +VIRTKRD G LS+A IDWVV AYT G VADEQMSAL MAI+ GM R EIARWTA Sbjct 1 MDVISVIRTKRDRGELSEAQIDWVVDAYTRGAVADEQMSALAMAILLNGMTRREIARWTA 60 Query 66 AMLASGARLDFTDLPLATVDKHSTGGVGDKITLPLVPVVAACGGAVPQASGRGLGHTGGT 125 AM+ASG R+DF+ L T DKHSTGGVGDKITLPL P+VAACG AVPQ SGRGLGHTGGT Sbjct 61 AMIASGERMDFSSLSRPTADKHSTGGVGDKITLPLAPLVAACGAAVPQLSGRGLGHTGGT 120 Query 126 LDKLESITGFTANLSNQRVREQLCDVGAAIFAAGQ-LAPADAKLYALRDITGTVESLPLI 184 LDKLE++ G+ A+LSN + + L GA I AAG LAPAD KLYALRD+TGTVE++PLI Sbjct 121 LDKLEAVPGWRASLSNAELMDVLDSTGAVICAAGDGLAPADKKLYALRDVTGTVEAIPLI 180 Query 185 ASSIMSKKLAEGAGALVLDVKVGSGAFMRSPVQARELAHTMVELGAAHGVPTRALLTEMN 244 ASSIMSKK+AEG G+LVLDVK GSGAFM++ ARELA TMV LG HGV T ALLT+M+ Sbjct 181 ASSIMSKKIAEGTGSLVLDVKCGSGAFMKNAADARELAETMVGLGTDHGVRTVALLTDMS 240 Query 245 CPLGRTVGNALEVAEALEVLAGGGPPDVVELTLRLAGEMLELAGIHGRDPAQTLRDGTAM 304 PLG T GNALEV E+LEVLAGGGP DVVELTL LA EML+ AG+ DPA+ L DG+AM Sbjct 241 TPLGLTAGNALEVRESLEVLAGGGPADVVELTLALAREMLDGAGLTDADPAKALADGSAM 300 Query 305 DRFRRLVAAQGGDLSKPLPIGSHSETVTAGASGTMGDIDAMAVGLAAWRLGAGRSRPGAR 364 D +RR++AAQGGD LP+ + VTA G + +DA +G+AAWRLGAGR+R Sbjct 301 DVWRRMIAAQGGDPDADLPVARETHVVTAPRDGVLTRLDAYDIGVAAWRLGAGRARKEDP 360 Query 365 VQHGAGVRIHRRPGEPVVVGEPLFTLYTNAPERFGAARAELAGGWSIRDSPP-QVRPLIV 423 VQ GAGV +H +PGEPV G+PL TL+T+ P+RF A + G + I ++ RP+++ Sbjct 361 VQAGAGVELHAKPGEPVRAGQPLLTLHTDTPDRFAYALESVEGSYDIEETGGLMARPIVL 420 Query 424 DRI 426 DR+ Sbjct 421 DRV 423 >gi|329935626|ref|ZP_08285433.1| thymidine phosphorylase [Streptomyces griseoaurantiacus M045] gi|329304887|gb|EGG48758.1| thymidine phosphorylase [Streptomyces griseoaurantiacus M045] Length=430 Score = 503 bits (1294), Expect = 3e-140, Method: Compositional matrix adjust. Identities = 271/429 (64%), Positives = 318/429 (75%), Gaps = 3/429 (0%) Query 1 VTDFAFDAPTVIRTKRDGGRLSDAAIDWVVKAYTDGRVADEQMSALLMAIVWRGMDRGEI 60 +T + DA +VIRTKRDGG LS A IDWV+ AYT G VAD QM+AL MAI+ GM+R EI Sbjct 1 MTSLSMDAVSVIRTKRDGGELSAAQIDWVIDAYTRGEVADYQMAALNMAILLNGMERHEI 60 Query 61 ARWTAAMLASGARLDFTDLPLATVDKHSTGGVGDKITLPLVPVVAACGGAVPQASGRGLG 120 ARWTAAM+ASG R+DF+ L T DKHSTGGVGDKITLPL P+VAACG AVPQ SGRGLG Sbjct 61 ARWTAAMIASGERMDFSSLSRPTADKHSTGGVGDKITLPLAPLVAACGAAVPQLSGRGLG 120 Query 121 HTGGTLDKLESITGFTANLSNQRVREQLCDVGAAIFAAGQ-LAPADAKLYALRDITGTVE 179 HTGGTLDKLESI G+ A LSN+ + L VGA I AAG LAPAD KLYALRD+TGTVE Sbjct 121 HTGGTLDKLESIPGWRALLSNEEMLSVLDGVGAVICAAGDGLAPADKKLYALRDVTGTVE 180 Query 180 SLPLIASSIMSKKLAEGAGALVLDVKVGSGAFMRSPVQARELAHTMVELGAAHGVPTRAL 239 S+PLIASSIMSKK+AEG G+LVLDVK GSGAFM++ ARELA TMV LG HGV T AL Sbjct 181 SIPLIASSIMSKKIAEGTGSLVLDVKAGSGAFMKTVEDARELARTMVGLGTDHGVKTVAL 240 Query 240 LTEMNCPLGRTVGNALEVAEALEVLAGGGPPDVVELTLRLAGEMLELAGIHGRDPAQTLR 299 LT+M+ PLG T GNALEV E++EVLAGGGP DVVELTL LA EML+ AG+ DPA+ L Sbjct 241 LTDMSTPLGLTAGNALEVRESVEVLAGGGPADVVELTLALAREMLDAAGLTDADPAKALA 300 Query 300 DGTAMDRFRRLVAAQGGDLSKPLPIGSHSETVTAGASGTMGDIDAMAVGLAAWRLGAGRS 359 DG+AMD +RR+++AQGGD PLP VTA ASG + +DA VG+AAWRLGAGR+ Sbjct 301 DGSAMDAWRRMISAQGGDPDAPLPTSREQHVVTAAASGVVARLDAYDVGVAAWRLGAGRA 360 Query 360 RPGARVQHGAGVRIHRRPGEPVVVGEPLFTLYTNAPERFGAARAELAGGWSIRDSPPQVR 419 R VQ AGV +H +PG+ V G+PL TL+T+ PERF A L I + Sbjct 361 RKEDPVQAAAGVELHAKPGDRVTEGQPLLTLHTDTPERFEYALKALENACDIAAQGAEFN 420 Query 420 --PLIVDRI 426 P++++RI Sbjct 421 RTPVVLERI 429 >gi|294631070|ref|ZP_06709630.1| thymidine phosphorylase [Streptomyces sp. e14] gi|292834403|gb|EFF92752.1| thymidine phosphorylase [Streptomyces sp. e14] Length=427 Score = 503 bits (1294), Expect = 4e-140, Method: Compositional matrix adjust. Identities = 271/426 (64%), Positives = 318/426 (75%), Gaps = 3/426 (0%) Query 4 FAFDAPTVIRTKRDGGRLSDAAIDWVVKAYTDGRVADEQMSALLMAIVWRGMDRGEIARW 63 A DA +VIRTKRD G LSD IDWV+ AYT G VADEQMSAL MAI+ GMDR EIARW Sbjct 1 MAMDAISVIRTKRDRGALSDEQIDWVIDAYTRGEVADEQMSALAMAILLNGMDRREIARW 60 Query 64 TAAMLASGARLDFTDLPLATVDKHSTGGVGDKITLPLVPVVAACGGAVPQASGRGLGHTG 123 TAAM+ASG R+DF+ L T DKHSTGGVGDKITLPL P+VAACG AVPQ SGRGLGHTG Sbjct 61 TAAMIASGERMDFSALSRPTADKHSTGGVGDKITLPLAPLVAACGAAVPQLSGRGLGHTG 120 Query 124 GTLDKLESITGFTANLSNQRVREQLCDVGAAIFAAGQ-LAPADAKLYALRDITGTVESLP 182 GTLDKLESI G+ A LSN+ + L VGA I AAG LAPAD KLYALRD+TGTVE++P Sbjct 121 GTLDKLESIPGWRALLSNEEMLSVLDGVGAVICAAGDGLAPADKKLYALRDVTGTVEAIP 180 Query 183 LIASSIMSKKLAEGAGALVLDVKVGSGAFMRSPVQARELAHTMVELGAAHGVPTRALLTE 242 LIASSIMSKK+AEG G+LVLDVKVGSGAFM++ ARELA TMV LG HGV T ALLT+ Sbjct 181 LIASSIMSKKIAEGTGSLVLDVKVGSGAFMKTIEDARELAATMVGLGTDHGVRTVALLTD 240 Query 243 MNCPLGRTVGNALEVAEALEVLAGGGPPDVVELTLRLAGEMLELAGIHGRDPAQTLRDGT 302 M+ PLG T GNALEV E++EVLAGGGP DVVELTL LA EML+ AG+ DPA+ L DG+ Sbjct 241 MSTPLGLTAGNALEVRESVEVLAGGGPADVVELTLALAREMLDAAGLKDADPAKALADGS 300 Query 303 AMDRFRRLVAAQGGDLSKPLPIGSHSETVTAGASGTMGDIDAMAVGLAAWRLGAGRSRPG 362 AMD +RR++AAQGGD LP +TA +SG + +DA +G+AAWRLGAGR+R Sbjct 301 AMDVWRRMIAAQGGDPDAALPTAKEQHVITAPSSGVLTRLDAYDIGVAAWRLGAGRARKE 360 Query 363 ARVQHGAGVRIHRRPGEPVVVGEPLFTLYTNAPERFGAARAELAGGWSIRD--SPPQVRP 420 VQ GAGV +H +PG+ V G PL TL+T+ P+RF A G + I +P P Sbjct 361 DPVQAGAGVELHAKPGDTVTAGRPLMTLHTDTPDRFDYALQATEGSYDIAPAGTPFTANP 420 Query 421 LIVDRI 426 ++++RI Sbjct 421 VVLERI 426 >gi|54022918|ref|YP_117160.1| thymidine phosphorylase [Nocardia farcinica IFM 10152] gi|54014426|dbj|BAD55796.1| putative thymidine phosphorylase [Nocardia farcinica IFM 10152] Length=427 Score = 501 bits (1289), Expect = 1e-139, Method: Compositional matrix adjust. Identities = 278/425 (66%), Positives = 320/425 (76%), Gaps = 4/425 (0%) Query 5 AFDAPTVIRTKRDGGRLSDAAIDWVVKAYTDGRVADEQMSALLMAIVWRGMDRGEIARWT 64 A DA ++I TKRDGG+LSD IDWV+ A+T G VADEQM+AL MAI+ RGM R E ARWT Sbjct 3 ALDAVSLITTKRDGGQLSDEQIDWVIDAFTRGAVADEQMAALAMAILLRGMTRRETARWT 62 Query 65 AAMLASGARLDFTDLPLATVDKHSTGGVGDKITLPLVPVVAACGGAVPQASGRGLGHTGG 124 AAM+ASG R+DFTDLP TVDKHSTGGVGDKITLPL P+VAACG AVPQ SGRGLGHTGG Sbjct 63 AAMIASGQRMDFTDLPRPTVDKHSTGGVGDKITLPLAPLVAACGAAVPQLSGRGLGHTGG 122 Query 125 TLDKLESITGFTANLSNQRVREQLCD--VGAAIFAAG-QLAPADAKLYALRDITGTVESL 181 TLDKLESI G+ A++ R+RE L D +GA I AAG LAPAD +LYALRD+TGTVES+ Sbjct 123 TLDKLESIPGWRADVPVARMREILADPAIGAVICAAGADLAPADKRLYALRDVTGTVESV 182 Query 182 PLIASSIMSKKLAEGAGALVLDVKVGSGAFMRSPVQARELAHTMVELGAAHGVPTRALLT 241 PLIASSIMSKK+AEG ALVLDVKVGSGAFM+ A ELA TMVELGA GV T ALLT Sbjct 183 PLIASSIMSKKIAEGTAALVLDVKVGSGAFMKDRATATELATTMVELGADAGVRTVALLT 242 Query 242 EMNCPLGRTVGNALEVAEALEVLAGGGPPDVVELTLRLAGEMLELAGIHGRDPAQTLRDG 301 M+ PLGRT GNALEVAEA+ VLAGGGP DVVELTL LA EM+ LAG+ DPA L G Sbjct 243 AMDSPLGRTAGNALEVAEAVAVLAGGGPADVVELTLALAREMVALAGLD-TDPADVLASG 301 Query 302 TAMDRFRRLVAAQGGDLSKPLPIGSHSETVTAGASGTMGDIDAMAVGLAAWRLGAGRSRP 361 AMD +R +V AQGGD PLP +H+E + A G + +DAM VG+AAWRLGAGR+R Sbjct 302 RAMDHWRAMVRAQGGDPDAPLPRATHTEILRADRDGVLTRLDAMGVGVAAWRLGAGRARQ 361 Query 362 GARVQHGAGVRIHRRPGEPVVVGEPLFTLYTNAPERFGAARAELAGGWSIRDSPPQVRPL 421 G VQHGAGV +H G+ V G+ L TL+T+ PE F +A A L G I D+ PL Sbjct 362 GDPVQHGAGVALHAGVGDRVTAGQALCTLHTDTPEAFDSAAAALREGIEIGDAAAGTGPL 421 Query 422 IVDRI 426 ++DRI Sbjct 422 VLDRI 426 >gi|297192493|ref|ZP_06909891.1| thymidine phosphorylase [Streptomyces pristinaespiralis ATCC 25486] gi|197718033|gb|EDY61941.1| thymidine phosphorylase [Streptomyces pristinaespiralis ATCC 25486] Length=425 Score = 501 bits (1289), Expect = 1e-139, Method: Compositional matrix adjust. Identities = 269/424 (64%), Positives = 315/424 (75%), Gaps = 3/424 (0%) Query 6 FDAPTVIRTKRDGGRLSDAAIDWVVKAYTDGRVADEQMSALLMAIVWRGMDRGEIARWTA 65 D +VIRTKRD G LS IDWV+ AYT G VADEQMSAL MAI+ GM+R EIARWTA Sbjct 1 MDVISVIRTKRDRGELSPQQIDWVIDAYTRGEVADEQMSALAMAILLNGMNRTEIARWTA 60 Query 66 AMLASGARLDFTDLPLATVDKHSTGGVGDKITLPLVPVVAACGGAVPQASGRGLGHTGGT 125 AM+ASG R++F L T DKHSTGGVGDKITLPL P+VAACG AVPQ SGRGLGHTGGT Sbjct 61 AMIASGERMNFDALSRPTADKHSTGGVGDKITLPLAPLVAACGAAVPQLSGRGLGHTGGT 120 Query 126 LDKLESITGFTANLSNQRVREQLCDVGAAIFAAGQ-LAPADAKLYALRDITGTVESLPLI 184 LDKLESI G+ A LSN+ + + L GA I AAG LAPAD KLYALRD+TGTVE++PLI Sbjct 121 LDKLESIPGWRALLSNEEMLDVLGTTGAVICAAGDGLAPADKKLYALRDVTGTVEAIPLI 180 Query 185 ASSIMSKKLAEGAGALVLDVKVGSGAFMRSPVQARELAHTMVELGAAHGVPTRALLTEMN 244 ASSIMSKK+AEG G+LVLDVKVG+GAFM++ ARELA TMV LG GV T ALLT+M+ Sbjct 181 ASSIMSKKIAEGTGSLVLDVKVGTGAFMKTIEDARELASTMVALGTDSGVKTVALLTDMS 240 Query 245 CPLGRTVGNALEVAEALEVLAGGGPPDVVELTLRLAGEMLELAGIHGRDPAQTLRDGTAM 304 PLG T GNALEV E++EVLAGGGP DVVELTL LA EML+ AGI DPA+ L DG+AM Sbjct 241 TPLGLTAGNALEVRESVEVLAGGGPADVVELTLALAREMLDAAGIKDADPAKALADGSAM 300 Query 305 DRFRRLVAAQGGDLSKPLPIGSHSETVTAGASGTMGDIDAMAVGLAAWRLGAGRSRPGAR 364 D +RR++AAQGGD LP+ VTA ASG + +DA VG+AAWRLGAGR+R Sbjct 301 DVWRRMIAAQGGDPDATLPVAREQHVVTAPASGVLTRLDAYDVGIAAWRLGAGRARKEDP 360 Query 365 VQHGAGVRIHRRPGEPVVVGEPLFTLYTNAPERFGAARAELAGGWSIRD--SPPQVRPLI 422 VQ GAGV IH +PG+ V G+PL TL+T+ PE+F A L W I + + P++ Sbjct 361 VQAGAGVEIHAKPGDTVTAGQPLLTLHTDTPEKFDYALESLGAAWDIAEPGTDFTATPIV 420 Query 423 VDRI 426 +DRI Sbjct 421 LDRI 424 >gi|295838601|ref|ZP_06825534.1| thymidine phosphorylase [Streptomyces sp. SPB74] gi|295827079|gb|EDY44706.2| thymidine phosphorylase [Streptomyces sp. SPB74] Length=426 Score = 500 bits (1288), Expect = 2e-139, Method: Compositional matrix adjust. Identities = 268/423 (64%), Positives = 316/423 (75%), Gaps = 2/423 (0%) Query 6 FDAPTVIRTKRDGGRLSDAAIDWVVKAYTDGRVADEQMSALLMAIVWRGMDRGEIARWTA 65 D +VIRTKRD G LS+A IDWVV AYT G VADEQMSAL MAI+ GM R EIARWTA Sbjct 1 MDVISVIRTKRDRGELSEAQIDWVVDAYTRGAVADEQMSALAMAILLNGMTRQEIARWTA 60 Query 66 AMLASGARLDFTDLPLATVDKHSTGGVGDKITLPLVPVVAACGGAVPQASGRGLGHTGGT 125 AM+ASG R+DF+ L T DKHSTGGVGDKITLPL P+VAACG AVPQ SGRGLGHTGGT Sbjct 61 AMIASGERMDFSSLSRPTADKHSTGGVGDKITLPLAPLVAACGAAVPQLSGRGLGHTGGT 120 Query 126 LDKLESITGFTANLSNQRVREQLCDVGAAIFAAGQ-LAPADAKLYALRDITGTVESLPLI 184 LDKLE+I G+ A+L+N + + L GA I AAG LAPAD KLYALRD+TGTVE++PLI Sbjct 121 LDKLEAIPGWRASLTNAELMDVLDSTGAVICAAGDGLAPADKKLYALRDVTGTVEAIPLI 180 Query 185 ASSIMSKKLAEGAGALVLDVKVGSGAFMRSPVQARELAHTMVELGAAHGVPTRALLTEMN 244 ASSIMSKK+AEG G+LVLDVK GSGAFM++ ARELA TMV LG HGV T ALLT+M+ Sbjct 181 ASSIMSKKIAEGTGSLVLDVKCGSGAFMKNEADARELAETMVGLGTDHGVRTVALLTDMS 240 Query 245 CPLGRTVGNALEVAEALEVLAGGGPPDVVELTLRLAGEMLELAGIHGRDPAQTLRDGTAM 304 PLG T GNALEV E++EVLAGGGP DVVELTL LA EML+ AG+ DPA+ L DG+AM Sbjct 241 TPLGLTAGNALEVRESVEVLAGGGPADVVELTLALAREMLDGAGLTDADPAKALADGSAM 300 Query 305 DRFRRLVAAQGGDLSKPLPIGSHSETVTAGASGTMGDIDAMAVGLAAWRLGAGRSRPGAR 364 D +RR++ AQGGD LP+ VTA G + +DA VG+AAWRLGAGR+R Sbjct 301 DVWRRMITAQGGDPDAELPVARERHVVTAPRDGVLTRLDAYDVGVAAWRLGAGRARKEDP 360 Query 365 VQHGAGVRIHRRPGEPVVVGEPLFTLYTNAPERFGAARAELAGGWSIRDSPP-QVRPLIV 423 VQ GAGV +H +PGEPV G PL TL+T+ P+RF A L G + I ++ RP+++ Sbjct 361 VQAGAGVELHAKPGEPVRSGHPLLTLHTDTPDRFAYALESLEGAYDIEETGGLMARPIVL 420 Query 424 DRI 426 DR+ Sbjct 421 DRV 423 >gi|21223264|ref|NP_629043.1| thymidine phosphorylase [Streptomyces coelicolor A3(2)] gi|13162079|emb|CAC33055.1| thymidine phosphorylase [Streptomyces coelicolor A3(2)] Length=427 Score = 499 bits (1284), Expect = 5e-139, Method: Compositional matrix adjust. Identities = 262/409 (65%), Positives = 309/409 (76%), Gaps = 1/409 (0%) Query 4 FAFDAPTVIRTKRDGGRLSDAAIDWVVKAYTDGRVADEQMSALLMAIVWRGMDRGEIARW 63 A D +VIRTKRD G L+ IDWV+ AYT G VADEQMS+L MAI+ GM+RGEIARW Sbjct 1 MAMDVISVIRTKRDRGELTGEQIDWVIDAYTRGEVADEQMSSLAMAILLNGMNRGEIARW 60 Query 64 TAAMLASGARLDFTDLPLATVDKHSTGGVGDKITLPLVPVVAACGGAVPQASGRGLGHTG 123 TAAM+ASG R+DF+ L T DKHSTGGVGDKITLPL P+VAACG AVPQ SGRGLGHTG Sbjct 61 TAAMIASGERMDFSSLSRPTADKHSTGGVGDKITLPLAPLVAACGAAVPQLSGRGLGHTG 120 Query 124 GTLDKLESITGFTANLSNQRVREQLCDVGAAIFAAGQ-LAPADAKLYALRDITGTVESLP 182 GTLDKLESI G+ A LSN+ + + L GA I AAG LAPAD KLYALRD+TGTVE++P Sbjct 121 GTLDKLESIPGWRALLSNEEMLDVLDTTGAVICAAGDGLAPADKKLYALRDVTGTVEAIP 180 Query 183 LIASSIMSKKLAEGAGALVLDVKVGSGAFMRSPVQARELAHTMVELGAAHGVPTRALLTE 242 LIASSIMSKK+AEG G+LVLDVKVGSGAFM++ ARELA TMV LG HGV T ALLT+ Sbjct 181 LIASSIMSKKIAEGTGSLVLDVKVGSGAFMKTIEDARELASTMVGLGTDHGVKTVALLTD 240 Query 243 MNCPLGRTVGNALEVAEALEVLAGGGPPDVVELTLRLAGEMLELAGIHGRDPAQTLRDGT 302 M PLG T GNALEV E++EVLAGGGP DVVELTL LA EML+ AG+ DPA+ L DG+ Sbjct 241 MATPLGLTAGNALEVRESVEVLAGGGPSDVVELTLALAREMLDAAGLKDADPAKALADGS 300 Query 303 AMDRFRRLVAAQGGDLSKPLPIGSHSETVTAGASGTMGDIDAMAVGLAAWRLGAGRSRPG 362 AMD +RR++AAQGGD LP + AGASG + +DA +G+AAWRLGAGR+R Sbjct 301 AMDVWRRMIAAQGGDPDAELPTSKEQHVIKAGASGVLTRLDAYDIGVAAWRLGAGRARKE 360 Query 363 ARVQHGAGVRIHRRPGEPVVVGEPLFTLYTNAPERFGAARAELAGGWSI 411 VQ AGV +H +PG+ V G+PL TL+T+ P+RF A A + G + + Sbjct 361 DPVQAAAGVELHAKPGDTVTAGQPLLTLHTDTPDRFEYALAAVQGAYDV 409 >gi|334336495|ref|YP_004541647.1| pyrimidine-nucleoside phosphorylase [Isoptericola variabilis 225] gi|334106863|gb|AEG43753.1| pyrimidine-nucleoside phosphorylase [Isoptericola variabilis 225] Length=436 Score = 499 bits (1284), Expect = 5e-139, Method: Compositional matrix adjust. Identities = 278/426 (66%), Positives = 319/426 (75%), Gaps = 5/426 (1%) Query 6 FDAPTVIRTKRDGGRLSDAAIDWVVKAYTDGRVADEQMSALLMAIVWRGMDRGEIARWTA 65 FDA VIRTKRD RLSDA IDWV+ AYT G VA+EQMSAL MAI+ GM R EI+RWTA Sbjct 10 FDAVDVIRTKRDRHRLSDAQIDWVIDAYTRGVVAEEQMSALAMAILLNGMSRAEISRWTA 69 Query 66 AMLASGARLDFTDLPLATVDKHSTGGVGDKITLPLVPVVAACGGAVPQASGRGLGHTGGT 125 AM+ASG R+DF+ L T DKHSTGGVGDKITLPL P+VA G AVPQ SGRGLGHTGGT Sbjct 70 AMIASGERMDFSSLSRPTADKHSTGGVGDKITLPLAPLVATFGVAVPQLSGRGLGHTGGT 129 Query 126 LDKLESITGFTANLSNQRVREQLCDVGAAIFAAGQ-LAPADAKLYALRDITGTVESLPLI 184 LDKLESI G+ A+LSN V QL DVGA I AAG LAPAD KLYALRD+TGTVE++PLI Sbjct 130 LDKLESIPGWRASLSNAEVLAQLEDVGAVICAAGAGLAPADKKLYALRDVTGTVEAIPLI 189 Query 185 ASSIMSKKLAEGAGALVLDVKVGSGAFMRSPVQARELAHTMVELGAAHGVPTRALLTEMN 244 ASSIMSKK+AEG GALVLDVKVGSGAFM+ QARELA TMV+LG GV T ALLT+M Sbjct 190 ASSIMSKKIAEGTGALVLDVKVGSGAFMKDVDQARELARTMVDLGTDAGVRTVALLTDME 249 Query 245 CPLGRTVGNALEVAEALEVLAGGGPPDVVELTLRLAGEMLELAGI-HGRDPA-QTLRDGT 302 PLGRT GNALEV E+L+VLAGGGP DVV+LT+ LA EML A G D + L DG Sbjct 250 VPLGRTAGNALEVRESLDVLAGGGPRDVVDLTVALAVEMLAAADRPTGEDEVRRALADGR 309 Query 303 AMDRFRRLVAAQGGDLSKPLPIGSHSETVTAGASGTMGDIDAMAVGLAAWRLGAGRSRPG 362 AMD +RR++AAQGGD LP+ +E V A +G + ++DA AVG+AAWRLGAGR R Sbjct 310 AMDTWRRMIAAQGGDPDAELPVARETEHVVADRTGVLAELDAYAVGVAAWRLGAGRGRRE 369 Query 363 ARVQHGAGVRIHRRPGEPVVVGEPLFTLYTNAPERFGAARAELAGGWSIRDSPPQV--RP 420 VQ GAGV IH +PG+ VV G+ L TL+T+ PERF AR L G WS+ + V RP Sbjct 370 DPVQAGAGVEIHAKPGDQVVAGQTLLTLHTDTPERFDRARDALEGAWSVAPAGTAVPTRP 429 Query 421 LIVDRI 426 L++DRI Sbjct 430 LVLDRI 435 >gi|302536416|ref|ZP_07288758.1| thymidine phosphorylase [Streptomyces sp. C] gi|302445311|gb|EFL17127.1| thymidine phosphorylase [Streptomyces sp. C] Length=425 Score = 498 bits (1283), Expect = 6e-139, Method: Compositional matrix adjust. Identities = 267/424 (63%), Positives = 314/424 (75%), Gaps = 3/424 (0%) Query 6 FDAPTVIRTKRDGGRLSDAAIDWVVKAYTDGRVADEQMSALLMAIVWRGMDRGEIARWTA 65 D +VIRTKRD G LS IDWV+ AYT G VADEQMSAL MAI+ GM+R EIARWTA Sbjct 1 MDVISVIRTKRDRGELSPEQIDWVIDAYTRGIVADEQMSALAMAILLNGMNRSEIARWTA 60 Query 66 AMLASGARLDFTDLPLATVDKHSTGGVGDKITLPLVPVVAACGGAVPQASGRGLGHTGGT 125 AM+ASG R++F L T DKHSTGGVGDKITLPL P+VAACG AVPQ SGRGLGHTGGT Sbjct 61 AMIASGERMNFDALSRPTADKHSTGGVGDKITLPLAPLVAACGAAVPQLSGRGLGHTGGT 120 Query 126 LDKLESITGFTANLSNQRVREQLCDVGAAIFAAGQ-LAPADAKLYALRDITGTVESLPLI 184 LDKLESI G+ A LSN+ + L GA I AAG LAPAD KLYALRD+TGTVE++PLI Sbjct 121 LDKLESIPGWRALLSNEEMLNVLDTTGAVICAAGDGLAPADKKLYALRDVTGTVEAIPLI 180 Query 185 ASSIMSKKLAEGAGALVLDVKVGSGAFMRSPVQARELAHTMVELGAAHGVPTRALLTEMN 244 ASSIMSKK+AEG G+LVLDVKVGSGAFM++ ARELA TMV LG GV T ALLT+M+ Sbjct 181 ASSIMSKKIAEGTGSLVLDVKVGSGAFMKNIEDARELASTMVALGTDSGVKTIALLTDMS 240 Query 245 CPLGRTVGNALEVAEALEVLAGGGPPDVVELTLRLAGEMLELAGIHGRDPAQTLRDGTAM 304 PLG T GNALEV E++EVLAGGGP DVVELT+ LA EML AGI DPA+ L DG+AM Sbjct 241 TPLGLTAGNALEVRESVEVLAGGGPADVVELTIALAQEMLTAAGIKDADPAKALADGSAM 300 Query 305 DRFRRLVAAQGGDLSKPLPIGSHSETVTAGASGTMGDIDAMAVGLAAWRLGAGRSRPGAR 364 D +RR+++AQGGD LP+ VTA ASG + +DA AVG+ AWRLGAGR+R Sbjct 301 DVWRRMISAQGGDPDAALPVAREQHVVTASASGVLTRLDAYAVGVGAWRLGAGRARKEDP 360 Query 365 VQHGAGVRIHRRPGEPVVVGEPLFTLYTNAPERFGAARAELAGGWSIRDSPP--QVRPLI 422 VQ GAG+ +H +PG+ V G+PL TL+T+ PE+F A A L G + + S P++ Sbjct 361 VQAGAGIELHAKPGDTVTAGQPLMTLHTDTPEKFEYALASLEGCYDVAPSGTGFSANPIV 420 Query 423 VDRI 426 +DRI Sbjct 421 LDRI 424 >gi|29829907|ref|NP_824541.1| thymidine phosphorylase [Streptomyces avermitilis MA-4680] gi|29607016|dbj|BAC71076.1| putative thymidine phosphorylase [Streptomyces avermitilis MA-4680] Length=427 Score = 498 bits (1281), Expect = 1e-138, Method: Compositional matrix adjust. Identities = 266/426 (63%), Positives = 319/426 (75%), Gaps = 3/426 (0%) Query 4 FAFDAPTVIRTKRDGGRLSDAAIDWVVKAYTDGRVADEQMSALLMAIVWRGMDRGEIARW 63 A DA +VIRTKRD G LSDA IDWV+ AYT G VAD QM+AL MAI+ GM+R EIARW Sbjct 1 MAMDAISVIRTKRDRGELSDAQIDWVIDAYTRGEVADYQMAALNMAILLNGMNRREIARW 60 Query 64 TAAMLASGARLDFTDLPLATVDKHSTGGVGDKITLPLVPVVAACGGAVPQASGRGLGHTG 123 TAAM+ASG R++F+ L T DKHSTGGVGDKITLPL P+VAACG AVPQ SGRGLGHTG Sbjct 61 TAAMIASGERMEFSALSRPTADKHSTGGVGDKITLPLAPLVAACGAAVPQLSGRGLGHTG 120 Query 124 GTLDKLESITGFTANLSNQRVREQLCDVGAAIFAAGQ-LAPADAKLYALRDITGTVESLP 182 GTLDKLESI G+ A LSN+ + L GA I AAG LAPAD KLYALRD+TGTVE++P Sbjct 121 GTLDKLESIPGWRALLSNEEMLHVLDTTGAVICAAGDGLAPADKKLYALRDVTGTVEAIP 180 Query 183 LIASSIMSKKLAEGAGALVLDVKVGSGAFMRSPVQARELAHTMVELGAAHGVPTRALLTE 242 LIASSIMSKK+AEG G+LVLDVKVGSGAFM++ ARELA TMV LG HGV T ALLT+ Sbjct 181 LIASSIMSKKIAEGTGSLVLDVKVGSGAFMKTIEDARELASTMVGLGTDHGVKTVALLTD 240 Query 243 MNCPLGRTVGNALEVAEALEVLAGGGPPDVVELTLRLAGEMLELAGIHGRDPAQTLRDGT 302 M+ PLG T GNALEV E++EVLAGGGP DVVELT+ LA EML+ AG+ DPA+ L DG+ Sbjct 241 MSTPLGLTAGNALEVRESVEVLAGGGPADVVELTVALAREMLDAAGVKDADPAKALADGS 300 Query 303 AMDRFRRLVAAQGGDLSKPLPIGSHSETVTAGASGTMGDIDAMAVGLAAWRLGAGRSRPG 362 AMD +RR++AAQGGD LP VTA +SG + +DA +G+AAWRLGAGR+R Sbjct 301 AMDVWRRMIAAQGGDPDAQLPTARERHVVTAPSSGVLTRLDAYDIGVAAWRLGAGRARKE 360 Query 363 ARVQHGAGVRIHRRPGEPVVVGEPLFTLYTNAPERFGAARAELAGGWSIRDSPPQVR--P 420 VQ GAG+ +H +PG+ V G+PL TL+T+ PERF A + G + I + + P Sbjct 361 DPVQAGAGIEMHAKPGDTVTAGQPLLTLHTDTPERFEYALESVDGSYDIAPTGTDFKATP 420 Query 421 LIVDRI 426 ++++RI Sbjct 421 VVLERI 426 >gi|302558816|ref|ZP_07311158.1| thymidine phosphorylase [Streptomyces griseoflavus Tu4000] gi|302476434|gb|EFL39527.1| thymidine phosphorylase [Streptomyces griseoflavus Tu4000] Length=427 Score = 497 bits (1280), Expect = 1e-138, Method: Compositional matrix adjust. Identities = 265/409 (65%), Positives = 310/409 (76%), Gaps = 1/409 (0%) Query 4 FAFDAPTVIRTKRDGGRLSDAAIDWVVKAYTDGRVADEQMSALLMAIVWRGMDRGEIARW 63 A D +VIRTKRD G LSD IDWV+ AYT G VADEQMSAL MAI+ GM+RGEIARW Sbjct 1 MAMDVISVIRTKRDRGELSDEQIDWVIDAYTRGEVADEQMSALAMAILLNGMNRGEIARW 60 Query 64 TAAMLASGARLDFTDLPLATVDKHSTGGVGDKITLPLVPVVAACGGAVPQASGRGLGHTG 123 TAAM+ASG R+DF+ L T DKHSTGGVGDKITLPL P+VAACG AVPQ SGRGLGHTG Sbjct 61 TAAMIASGERMDFSSLSRPTADKHSTGGVGDKITLPLAPLVAACGAAVPQLSGRGLGHTG 120 Query 124 GTLDKLESITGFTANLSNQRVREQLCDVGAAIFAAGQ-LAPADAKLYALRDITGTVESLP 182 GTLDKLESI G+ A LSN+ + L GA I AAG LAPAD KLYALRD+TGTVE++P Sbjct 121 GTLDKLESIPGWRALLSNEEMLSVLDGAGAVICAAGDGLAPADKKLYALRDVTGTVEAIP 180 Query 183 LIASSIMSKKLAEGAGALVLDVKVGSGAFMRSPVQARELAHTMVELGAAHGVPTRALLTE 242 LIASSIMSKK+AEG G+LVLDVKVG+GAFM++ ARELA TMV LG GV T ALLT+ Sbjct 181 LIASSIMSKKIAEGTGSLVLDVKVGTGAFMKTIEDARELARTMVGLGTDSGVRTVALLTD 240 Query 243 MNCPLGRTVGNALEVAEALEVLAGGGPPDVVELTLRLAGEMLELAGIHGRDPAQTLRDGT 302 M+ PLG T GNALEV E++EVLAGGGP DVVELTL LA EML+ AG+ DPA+ L DG+ Sbjct 241 MSTPLGLTAGNALEVRESVEVLAGGGPADVVELTLALAREMLDAAGLKDADPAKALADGS 300 Query 303 AMDRFRRLVAAQGGDLSKPLPIGSHSETVTAGASGTMGDIDAMAVGLAAWRLGAGRSRPG 362 AMD +RR++AAQGGD LP+ V A +SG + +DA VG+AAWRLGAGR+R Sbjct 301 AMDVWRRMIAAQGGDPDAELPVAREQHVVKAPSSGVLTRLDAYGVGVAAWRLGAGRARKE 360 Query 363 ARVQHGAGVRIHRRPGEPVVVGEPLFTLYTNAPERFGAARAELAGGWSI 411 VQ GAGV +H +PG+ V G+PL TL+T+ P+RF A +AG + I Sbjct 361 DPVQAGAGVELHAKPGDEVTEGQPLLTLHTDTPDRFDYALQAVAGSYDI 409 >gi|302553742|ref|ZP_07306084.1| thymidine phosphorylase [Streptomyces viridochromogenes DSM 40736] gi|302471360|gb|EFL34453.1| thymidine phosphorylase [Streptomyces viridochromogenes DSM 40736] Length=427 Score = 496 bits (1278), Expect = 3e-138, Method: Compositional matrix adjust. Identities = 265/426 (63%), Positives = 316/426 (75%), Gaps = 3/426 (0%) Query 4 FAFDAPTVIRTKRDGGRLSDAAIDWVVKAYTDGRVADEQMSALLMAIVWRGMDRGEIARW 63 A DA +VIRTKRD G LSD IDWV+ AYT G VADEQMSAL MAI+ GM+R EIARW Sbjct 1 MAMDAISVIRTKRDRGELSDEQIDWVIDAYTRGEVADEQMSALAMAILLNGMNRREIARW 60 Query 64 TAAMLASGARLDFTDLPLATVDKHSTGGVGDKITLPLVPVVAACGGAVPQASGRGLGHTG 123 TAAM+ASG R+DF+ L T DKHSTGGVGDKITLPL P+VAACG AVPQ SGRGLGHTG Sbjct 61 TAAMIASGERMDFSSLSRPTADKHSTGGVGDKITLPLAPLVAACGAAVPQLSGRGLGHTG 120 Query 124 GTLDKLESITGFTANLSNQRVREQLCDVGAAIFAAGQ-LAPADAKLYALRDITGTVESLP 182 GTLDKLESI G+ A LSN+ + L GA I AAG LAPAD KLYALRD+TGTVE++P Sbjct 121 GTLDKLESIPGWRALLSNEEMLSVLDGTGAVICAAGDGLAPADKKLYALRDVTGTVEAIP 180 Query 183 LIASSIMSKKLAEGAGALVLDVKVGSGAFMRSPVQARELAHTMVELGAAHGVPTRALLTE 242 LIASSIMSKK+AEG G+LVLDVKVG GAFM++ ARELA TMV LG HGV T ALLT+ Sbjct 181 LIASSIMSKKIAEGTGSLVLDVKVGMGAFMKTIEDARELASTMVGLGTDHGVKTVALLTD 240 Query 243 MNCPLGRTVGNALEVAEALEVLAGGGPPDVVELTLRLAGEMLELAGIHGRDPAQTLRDGT 302 M+ PLG T GNALEV E++EVLAGGGP DVVELT+ LA EML+ AG+ DPA+ L DG+ Sbjct 241 MSTPLGLTAGNALEVRESVEVLAGGGPADVVELTIALAREMLDAAGVKDADPAKALADGS 300 Query 303 AMDRFRRLVAAQGGDLSKPLPIGSHSETVTAGASGTMGDIDAMAVGLAAWRLGAGRSRPG 362 AMD +RR++ AQGGD LP+ + A +SG + +DA +G+AAWRLGAGR+R Sbjct 301 AMDVWRRMIKAQGGDPDAALPVSREQHVIKAPSSGVLTRLDAYDIGVAAWRLGAGRARKE 360 Query 363 ARVQHGAGVRIHRRPGEPVVVGEPLFTLYTNAPERFGAARAELAGGWSIR--DSPPQVRP 420 VQ GAGV +H +PG+ V G+PL TL+T+ PERF A + G + I + P Sbjct 361 DPVQAGAGVELHAKPGDTVTEGQPLLTLHTDTPERFDYALQAVEGSYDIAAPGTDFTASP 420 Query 421 LIVDRI 426 ++++RI Sbjct 421 VVLERI 426 >gi|116669703|ref|YP_830636.1| thymidine phosphorylase [Arthrobacter sp. FB24] gi|116609812|gb|ABK02536.1| thymidine phosphorylase [Arthrobacter sp. FB24] Length=440 Score = 496 bits (1278), Expect = 3e-138, Method: Compositional matrix adjust. Identities = 272/432 (63%), Positives = 319/432 (74%), Gaps = 12/432 (2%) Query 5 AFDAPTVIRTKRDGGRLSDAAIDWVVKAYTDGRVADEQMSALLMAIVWRGMDRGEIARWT 64 AFDA +IR KRD G LS A IDW + AYT G +ADEQM+AL MAI+ GMDR EI+RWT Sbjct 10 AFDAVDIIRIKRDRGVLSPAQIDWTIDAYTRGAIADEQMAALNMAILLNGMDRAEISRWT 69 Query 65 AAMLASGARLDFTDLPLA------TVDKHSTGGVGDKITLPLVPVVAACGGAVPQASGRG 118 AAM+ASG R+DF+ L A T DKHSTGGVGDKITLPL P+VA G AVPQ SGRG Sbjct 70 AAMIASGERMDFSGLRRADGSVKPTSDKHSTGGVGDKITLPLAPLVAVFGVAVPQLSGRG 129 Query 119 LGHTGGTLDKLESITGFTANLSNQRVREQLCDVGAAIFAAGQ-LAPADAKLYALRDITGT 177 LGHTGGTLDKLE+I G+ A LSN + QL +VGA I AAG LAPAD KLYALRD+TGT Sbjct 130 LGHTGGTLDKLEAIPGWRAGLSNDEMMAQLQNVGAVICAAGAGLAPADKKLYALRDVTGT 189 Query 178 VESLPLIASSIMSKKLAEGAGALVLDVKVGSGAFMRSPVQARELAHTMVELGAAHGVPTR 237 VE++PLIASSIMSKK+AEG G+LVLDVKVGSGAFM+ +ARELA TMV LG GV T Sbjct 190 VEAIPLIASSIMSKKIAEGTGSLVLDVKVGSGAFMKDEARARELAETMVALGKDAGVNTV 249 Query 238 ALLTEMNCPLGRTVGNALEVAEALEVLAGGGPPDVVELTLRLAGEMLELAGIHGRDPAQT 297 ALLT MN PLG T GN++EV E++EVLAGGGP DVVELT+RLA EML AG+H DP Sbjct 250 ALLTNMNTPLGLTAGNSIEVEESVEVLAGGGPEDVVELTVRLAEEMLACAGVHDADPRAA 309 Query 298 LRDGTAMDRFRRLVAAQGGDLSKPLPIGSHSETVTAGASGTMGDIDAMAVGLAAWRLGAG 357 L+DG AMD + R++ AQGGD LP+ SE V A A G + ++DA+AVG+AAWRLGAG Sbjct 310 LKDGRAMDVWNRMIEAQGGDPRAKLPVARESEVVYAPADGVLVELDALAVGVAAWRLGAG 369 Query 358 RSRPGARVQHGAGVRIHRRPGEPVVVGEPLFTLYTNAPERFGAARAELAGGWSIRDSPPQ 417 R+R +VQ GAGVR+H +PG V GEPL TL T+ PE+F A+ L G S+ +P Sbjct 370 RARKEDQVQAGAGVRLHAKPGAVVRAGEPLMTLLTDTPEKFERAKEALEG--SVVIAPEG 427 Query 418 VRP---LIVDRI 426 RP LI+DRI Sbjct 428 SRPAQKLIIDRI 439 Lambda K H 0.319 0.136 0.399 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 871320876120 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40