BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv3339c Length=409 Score E Sequences producing significant alignments: (Bits) Value gi|294995893|ref|ZP_06801584.1| isocitrate dehydrogenase [Mycoba... 858 0.0 gi|15610475|ref|NP_217856.1| isocitrate dehydrogenase [Mycobacte... 848 0.0 gi|254233949|ref|ZP_04927274.1| isocitrate dehydrogenase [NADP] ... 847 0.0 gi|289752039|ref|ZP_06511417.1| isocitrate dehydrogenase [NADP] ... 847 0.0 gi|121639267|ref|YP_979491.1| isocitrate dehydrogenase [Mycobact... 847 0.0 gi|339296166|gb|AEJ48277.1| isocitrate dehydrogenase [Mycobacter... 847 0.0 gi|340628323|ref|YP_004746775.1| putative isocitrate dehydrogena... 846 0.0 gi|183981208|ref|YP_001849499.1| isocitrate dehydrogenase [NADP]... 776 0.0 gi|240169086|ref|ZP_04747745.1| isocitrate dehydrogenase [Mycoba... 771 0.0 gi|254820256|ref|ZP_05225257.1| isocitrate dehydrogenase [Mycoba... 770 0.0 gi|41409553|ref|NP_962389.1| isocitrate dehydrogenase [Mycobacte... 767 0.0 gi|118464587|ref|YP_883449.1| isocitrate dehydrogenase [Mycobact... 766 0.0 gi|296168845|ref|ZP_06850517.1| isocitrate dehydrogenase [Mycoba... 766 0.0 gi|342861559|ref|ZP_08718206.1| isocitrate dehydrogenase [Mycoba... 765 0.0 gi|333921640|ref|YP_004495221.1| isocitrate dehydrogenase [NADP]... 701 0.0 gi|312140780|ref|YP_004008116.1| nADP-dependent isocitrate dehyd... 694 0.0 gi|54022890|ref|YP_117132.1| isocitrate dehydrogenase [Nocardia ... 684 0.0 gi|336320051|ref|YP_004600019.1| isocitrate dehydrogenase, NADP-... 680 0.0 gi|229489415|ref|ZP_04383278.1| isocitrate dehydrogenase, NADP-d... 679 0.0 gi|317508482|ref|ZP_07966150.1| isocitrate dehydrogenase [Segnil... 678 0.0 gi|296130365|ref|YP_003637615.1| isocitrate dehydrogenase, NADP-... 678 0.0 gi|226305492|ref|YP_002765452.1| NADP-dependent isocitrate dehyd... 677 0.0 gi|332669636|ref|YP_004452644.1| NADP-dependent isocitrate dehyd... 677 0.0 gi|296394293|ref|YP_003659177.1| NADP-dependent isocitrate dehyd... 672 0.0 gi|319948743|ref|ZP_08022863.1| isocitrate dehydrogenase [Dietzi... 672 0.0 gi|326381935|ref|ZP_08203628.1| isocitrate dehydrogenase [Gordon... 672 0.0 gi|256380465|ref|YP_003104125.1| isocitrate dehydrogenase [Actin... 671 0.0 gi|111023201|ref|YP_706173.1| isocitrate dehydrogenase [Rhodococ... 670 0.0 gi|269128405|ref|YP_003301775.1| isocitrate dehydrogenase, NADP-... 670 0.0 gi|72162967|ref|YP_290624.1| isocitrate dehydrogenase [Thermobif... 669 0.0 gi|163839010|ref|YP_001623415.1| isocitrate dehydrogenase [Renib... 668 0.0 gi|297562889|ref|YP_003681863.1| isocitrate dehydrogenase, NADP-... 664 0.0 gi|296268651|ref|YP_003651283.1| isocitrate dehydrogenase, NADP-... 664 0.0 gi|302524145|ref|ZP_07276487.1| isocitrate dehydrogenase, NADP-d... 664 0.0 gi|256831925|ref|YP_003160652.1| isocitrate dehydrogenase, NADP-... 663 0.0 gi|226365706|ref|YP_002783489.1| isocitrate dehydrogenase [Rhodo... 662 0.0 gi|297625896|ref|YP_003687659.1| isocitrate/isopropylmalate dehy... 660 0.0 gi|229821488|ref|YP_002883014.1| isocitrate dehydrogenase [Beute... 657 0.0 gi|257054575|ref|YP_003132407.1| isocitrate dehydrogenase [Sacch... 656 0.0 gi|117927597|ref|YP_872148.1| isocitrate dehydrogenase [Acidothe... 654 0.0 gi|134103066|ref|YP_001108727.1| isocitrate dehydrogenase [Sacch... 652 0.0 gi|300782764|ref|YP_003763055.1| isocitrate dehydrogenase [Amyco... 652 0.0 gi|271962799|ref|YP_003336995.1| isocitrate dehydrogenase (NADP(... 650 0.0 gi|238060986|ref|ZP_04605695.1| isocitrate dehydrogenase [Microm... 649 0.0 gi|152967931|ref|YP_001363715.1| isocitrate dehydrogenase [Kineo... 649 0.0 gi|331699060|ref|YP_004335299.1| isocitrate dehydrogenase, NADP-... 648 0.0 gi|302869826|ref|YP_003838463.1| isocitrate dehydrogenase, NADP-... 647 0.0 gi|50955486|ref|YP_062774.1| isocitrate dehydrogenase [Leifsonia... 647 0.0 gi|284992784|ref|YP_003411338.1| isocitrate dehydrogenase, NADP-... 646 0.0 gi|258651518|ref|YP_003200674.1| isocitrate dehydrogenase [Nakam... 646 0.0 >gi|294995893|ref|ZP_06801584.1| isocitrate dehydrogenase [Mycobacterium tuberculosis 210] Length=560 Score = 858 bits (2216), Expect = 0.0, Method: Compositional matrix adjust. Identities = 404/405 (99%), Positives = 405/405 (100%), Gaps = 0/405 (0%) Query 1 MSNAPKIKVSGPVVELDGDEMTRVIWKLIKDMLILPYLDIRLDYYDLGIEHRDATDDQVT 60 MSNAPKIKVSGPVVELDGDEMTRVIWKLIKDMLILPYLDIRLDYYDLGIEHRDATDDQVT Sbjct 1 MSNAPKIKVSGPVVELDGDEMTRVIWKLIKDMLILPYLDIRLDYYDLGIEHRDATDDQVT 60 Query 61 IDAAYAIKKHGVGVKCATITPDEARVEEFNLKKMWLSPNGTIRNILGGTIFREPIVISNV 120 IDAAYAIKKHGVGVKCATITPDEARVEEFNLKKMWLSPNGTIRNILGGTIFREPIVISNV Sbjct 61 IDAAYAIKKHGVGVKCATITPDEARVEEFNLKKMWLSPNGTIRNILGGTIFREPIVISNV 120 Query 121 PRLVPGWTKPIVIGRHAFGDQYRATNFKVDQPGTVTLTFTPADGSAPIVHEMVSIPEDGG 180 PRLVPGWTKPIVIGRHAFGDQYRATNFKVDQPGTVTLTFTPADGSAPIVHEMVSIPEDGG Sbjct 121 PRLVPGWTKPIVIGRHAFGDQYRATNFKVDQPGTVTLTFTPADGSAPIVHEMVSIPEDGG 180 Query 181 VVLGMYNFKESIRDFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFERVYEEEFKA 240 VVLGMYNFKESIRDFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFERVYEEEFKA Sbjct 181 VVLGMYNFKESIRDFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFERVYEEEFKA 240 Query 241 QFEAAGLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMT 300 QFEAAGLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMT Sbjct 241 QFEAAGLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMT 300 Query 301 ADGKTVEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAH 360 ADGKTVEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAH Sbjct 301 ADGKTVEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAH 360 Query 361 KLESVVIATVESGKMTKDLAILIGPEQDWLNSEEFLDAIADNLEK 405 KLESVVIATVESGKMTKDLAILIGPEQDWLNSEEFLDAIADNLE+ Sbjct 361 KLESVVIATVESGKMTKDLAILIGPEQDWLNSEEFLDAIADNLER 405 >gi|15610475|ref|NP_217856.1| isocitrate dehydrogenase [Mycobacterium tuberculosis H37Rv] gi|15842935|ref|NP_337972.1| isocitrate dehydrogenase [Mycobacterium tuberculosis CDC1551] gi|31794523|ref|NP_857016.1| isocitrate dehydrogenase [Mycobacterium bovis AF2122/97] 70 more sequence titles Length=409 Score = 848 bits (2192), Expect = 0.0, Method: Compositional matrix adjust. Identities = 409/409 (100%), Positives = 409/409 (100%), Gaps = 0/409 (0%) Query 1 MSNAPKIKVSGPVVELDGDEMTRVIWKLIKDMLILPYLDIRLDYYDLGIEHRDATDDQVT 60 MSNAPKIKVSGPVVELDGDEMTRVIWKLIKDMLILPYLDIRLDYYDLGIEHRDATDDQVT Sbjct 1 MSNAPKIKVSGPVVELDGDEMTRVIWKLIKDMLILPYLDIRLDYYDLGIEHRDATDDQVT 60 Query 61 IDAAYAIKKHGVGVKCATITPDEARVEEFNLKKMWLSPNGTIRNILGGTIFREPIVISNV 120 IDAAYAIKKHGVGVKCATITPDEARVEEFNLKKMWLSPNGTIRNILGGTIFREPIVISNV Sbjct 61 IDAAYAIKKHGVGVKCATITPDEARVEEFNLKKMWLSPNGTIRNILGGTIFREPIVISNV 120 Query 121 PRLVPGWTKPIVIGRHAFGDQYRATNFKVDQPGTVTLTFTPADGSAPIVHEMVSIPEDGG 180 PRLVPGWTKPIVIGRHAFGDQYRATNFKVDQPGTVTLTFTPADGSAPIVHEMVSIPEDGG Sbjct 121 PRLVPGWTKPIVIGRHAFGDQYRATNFKVDQPGTVTLTFTPADGSAPIVHEMVSIPEDGG 180 Query 181 VVLGMYNFKESIRDFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFERVYEEEFKA 240 VVLGMYNFKESIRDFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFERVYEEEFKA Sbjct 181 VVLGMYNFKESIRDFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFERVYEEEFKA 240 Query 241 QFEAAGLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMT 300 QFEAAGLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMT Sbjct 241 QFEAAGLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMT 300 Query 301 ADGKTVEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAH 360 ADGKTVEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAH Sbjct 301 ADGKTVEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAH 360 Query 361 KLESVVIATVESGKMTKDLAILIGPEQDWLNSEEFLDAIADNLEKELAN 409 KLESVVIATVESGKMTKDLAILIGPEQDWLNSEEFLDAIADNLEKELAN Sbjct 361 KLESVVIATVESGKMTKDLAILIGPEQDWLNSEEFLDAIADNLEKELAN 409 >gi|254233949|ref|ZP_04927274.1| isocitrate dehydrogenase [NADP] icd1 [Mycobacterium tuberculosis C] gi|124599478|gb|EAY58582.1| isocitrate dehydrogenase [NADP] icd1 [Mycobacterium tuberculosis C] Length=413 Score = 847 bits (2189), Expect = 0.0, Method: Compositional matrix adjust. Identities = 409/409 (100%), Positives = 409/409 (100%), Gaps = 0/409 (0%) Query 1 MSNAPKIKVSGPVVELDGDEMTRVIWKLIKDMLILPYLDIRLDYYDLGIEHRDATDDQVT 60 MSNAPKIKVSGPVVELDGDEMTRVIWKLIKDMLILPYLDIRLDYYDLGIEHRDATDDQVT Sbjct 5 MSNAPKIKVSGPVVELDGDEMTRVIWKLIKDMLILPYLDIRLDYYDLGIEHRDATDDQVT 64 Query 61 IDAAYAIKKHGVGVKCATITPDEARVEEFNLKKMWLSPNGTIRNILGGTIFREPIVISNV 120 IDAAYAIKKHGVGVKCATITPDEARVEEFNLKKMWLSPNGTIRNILGGTIFREPIVISNV Sbjct 65 IDAAYAIKKHGVGVKCATITPDEARVEEFNLKKMWLSPNGTIRNILGGTIFREPIVISNV 124 Query 121 PRLVPGWTKPIVIGRHAFGDQYRATNFKVDQPGTVTLTFTPADGSAPIVHEMVSIPEDGG 180 PRLVPGWTKPIVIGRHAFGDQYRATNFKVDQPGTVTLTFTPADGSAPIVHEMVSIPEDGG Sbjct 125 PRLVPGWTKPIVIGRHAFGDQYRATNFKVDQPGTVTLTFTPADGSAPIVHEMVSIPEDGG 184 Query 181 VVLGMYNFKESIRDFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFERVYEEEFKA 240 VVLGMYNFKESIRDFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFERVYEEEFKA Sbjct 185 VVLGMYNFKESIRDFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFERVYEEEFKA 244 Query 241 QFEAAGLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMT 300 QFEAAGLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMT Sbjct 245 QFEAAGLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMT 304 Query 301 ADGKTVEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAH 360 ADGKTVEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAH Sbjct 305 ADGKTVEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAH 364 Query 361 KLESVVIATVESGKMTKDLAILIGPEQDWLNSEEFLDAIADNLEKELAN 409 KLESVVIATVESGKMTKDLAILIGPEQDWLNSEEFLDAIADNLEKELAN Sbjct 365 KLESVVIATVESGKMTKDLAILIGPEQDWLNSEEFLDAIADNLEKELAN 413 >gi|289752039|ref|ZP_06511417.1| isocitrate dehydrogenase [NADP] icd1 [Mycobacterium tuberculosis T92] gi|289692626|gb|EFD60055.1| isocitrate dehydrogenase [NADP] icd1 [Mycobacterium tuberculosis T92] Length=409 Score = 847 bits (2188), Expect = 0.0, Method: Compositional matrix adjust. Identities = 408/409 (99%), Positives = 409/409 (100%), Gaps = 0/409 (0%) Query 1 MSNAPKIKVSGPVVELDGDEMTRVIWKLIKDMLILPYLDIRLDYYDLGIEHRDATDDQVT 60 MSNAPKIKVSGPVVELDGDEMTRVIWKLIKDMLILPYLDIRLDYYDLGIEHRDATDDQVT Sbjct 1 MSNAPKIKVSGPVVELDGDEMTRVIWKLIKDMLILPYLDIRLDYYDLGIEHRDATDDQVT 60 Query 61 IDAAYAIKKHGVGVKCATITPDEARVEEFNLKKMWLSPNGTIRNILGGTIFREPIVISNV 120 IDAAYAIKKHGVGVKCATITPDEARVEEFNLKKMWLSPNGTIRNILGGTIFREPIVISN+ Sbjct 61 IDAAYAIKKHGVGVKCATITPDEARVEEFNLKKMWLSPNGTIRNILGGTIFREPIVISNM 120 Query 121 PRLVPGWTKPIVIGRHAFGDQYRATNFKVDQPGTVTLTFTPADGSAPIVHEMVSIPEDGG 180 PRLVPGWTKPIVIGRHAFGDQYRATNFKVDQPGTVTLTFTPADGSAPIVHEMVSIPEDGG Sbjct 121 PRLVPGWTKPIVIGRHAFGDQYRATNFKVDQPGTVTLTFTPADGSAPIVHEMVSIPEDGG 180 Query 181 VVLGMYNFKESIRDFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFERVYEEEFKA 240 VVLGMYNFKESIRDFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFERVYEEEFKA Sbjct 181 VVLGMYNFKESIRDFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFERVYEEEFKA 240 Query 241 QFEAAGLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMT 300 QFEAAGLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMT Sbjct 241 QFEAAGLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMT 300 Query 301 ADGKTVEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAH 360 ADGKTVEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAH Sbjct 301 ADGKTVEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAH 360 Query 361 KLESVVIATVESGKMTKDLAILIGPEQDWLNSEEFLDAIADNLEKELAN 409 KLESVVIATVESGKMTKDLAILIGPEQDWLNSEEFLDAIADNLEKELAN Sbjct 361 KLESVVIATVESGKMTKDLAILIGPEQDWLNSEEFLDAIADNLEKELAN 409 >gi|121639267|ref|YP_979491.1| isocitrate dehydrogenase [Mycobacterium bovis BCG str. Pasteur 1173P2] gi|121494915|emb|CAL73398.1| Probable isocitrate dehydrogenase [NADP] icd1 [Mycobacterium bovis BCG str. Pasteur 1173P2] Length=409 Score = 847 bits (2188), Expect = 0.0, Method: Compositional matrix adjust. Identities = 408/409 (99%), Positives = 408/409 (99%), Gaps = 0/409 (0%) Query 1 MSNAPKIKVSGPVVELDGDEMTRVIWKLIKDMLILPYLDIRLDYYDLGIEHRDATDDQVT 60 MSNAPKIKVSGPVVELDGDEMTRVIWKLIKDMLILPYLDIRLDYYDLGIEHRDATDDQVT Sbjct 1 MSNAPKIKVSGPVVELDGDEMTRVIWKLIKDMLILPYLDIRLDYYDLGIEHRDATDDQVT 60 Query 61 IDAAYAIKKHGVGVKCATITPDEARVEEFNLKKMWLSPNGTIRNILGGTIFREPIVISNV 120 IDAAYAIKKHGVGVKCATITPDEARVEEFNLKKMWLSPNGTIRNILGGTIFREPIVISNV Sbjct 61 IDAAYAIKKHGVGVKCATITPDEARVEEFNLKKMWLSPNGTIRNILGGTIFREPIVISNV 120 Query 121 PRLVPGWTKPIVIGRHAFGDQYRATNFKVDQPGTVTLTFTPADGSAPIVHEMVSIPEDGG 180 PRLVPGWTKPIVIGRHAFGDQYRATNFKVDQPGTVTLTFTPADGSAPIVHEMVSIPEDGG Sbjct 121 PRLVPGWTKPIVIGRHAFGDQYRATNFKVDQPGTVTLTFTPADGSAPIVHEMVSIPEDGG 180 Query 181 VVLGMYNFKESIRDFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFERVYEEEFKA 240 VVLGMYNFKESIRDFAR SFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFERVYEEEFKA Sbjct 181 VVLGMYNFKESIRDFARVSFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFERVYEEEFKA 240 Query 241 QFEAAGLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMT 300 QFEAAGLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMT Sbjct 241 QFEAAGLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMT 300 Query 301 ADGKTVEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAH 360 ADGKTVEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAH Sbjct 301 ADGKTVEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAH 360 Query 361 KLESVVIATVESGKMTKDLAILIGPEQDWLNSEEFLDAIADNLEKELAN 409 KLESVVIATVESGKMTKDLAILIGPEQDWLNSEEFLDAIADNLEKELAN Sbjct 361 KLESVVIATVESGKMTKDLAILIGPEQDWLNSEEFLDAIADNLEKELAN 409 >gi|339296166|gb|AEJ48277.1| isocitrate dehydrogenase [Mycobacterium tuberculosis CCDC5079] Length=409 Score = 847 bits (2187), Expect = 0.0, Method: Compositional matrix adjust. Identities = 408/409 (99%), Positives = 409/409 (100%), Gaps = 0/409 (0%) Query 1 MSNAPKIKVSGPVVELDGDEMTRVIWKLIKDMLILPYLDIRLDYYDLGIEHRDATDDQVT 60 MSNAPKIKVSGPVVELDGDEMTRVIWKLIKDMLILPYLDIRLDYYDLGIEHRDATDDQVT Sbjct 1 MSNAPKIKVSGPVVELDGDEMTRVIWKLIKDMLILPYLDIRLDYYDLGIEHRDATDDQVT 60 Query 61 IDAAYAIKKHGVGVKCATITPDEARVEEFNLKKMWLSPNGTIRNILGGTIFREPIVISNV 120 IDAAYAIKKHGVGVKCATITPDEARVEEFNLKKMWLSPNGTIRNILGGTIFREPIVISNV Sbjct 61 IDAAYAIKKHGVGVKCATITPDEARVEEFNLKKMWLSPNGTIRNILGGTIFREPIVISNV 120 Query 121 PRLVPGWTKPIVIGRHAFGDQYRATNFKVDQPGTVTLTFTPADGSAPIVHEMVSIPEDGG 180 PRLVPGWTKPIVIGRHAFGDQYRATNFKVDQPGTVTLTFTPADGSAPIVHEMVSIPEDGG Sbjct 121 PRLVPGWTKPIVIGRHAFGDQYRATNFKVDQPGTVTLTFTPADGSAPIVHEMVSIPEDGG 180 Query 181 VVLGMYNFKESIRDFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFERVYEEEFKA 240 VVLGMYNFKESIRDFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFERVYEEEFKA Sbjct 181 VVLGMYNFKESIRDFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFERVYEEEFKA 240 Query 241 QFEAAGLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMT 300 QFEAAGLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMT Sbjct 241 QFEAAGLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMT 300 Query 301 ADGKTVEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAH 360 ADGKTVEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAH Sbjct 301 ADGKTVEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAH 360 Query 361 KLESVVIATVESGKMTKDLAILIGPEQDWLNSEEFLDAIADNLEKELAN 409 KLESVVIATVESGKMTKDLAILIGPEQDWLNSEEFLDAIADNLE+ELAN Sbjct 361 KLESVVIATVESGKMTKDLAILIGPEQDWLNSEEFLDAIADNLEEELAN 409 >gi|340628323|ref|YP_004746775.1| putative isocitrate dehydrogenase [NADP] ICD1 [Mycobacterium canettii CIPT 140010059] gi|340006513|emb|CCC45697.1| putative isocitrate dehydrogenase [NADP] ICD1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) [Mycobacterium canettii CIPT 140010059] Length=409 Score = 846 bits (2185), Expect = 0.0, Method: Compositional matrix adjust. Identities = 408/409 (99%), Positives = 408/409 (99%), Gaps = 0/409 (0%) Query 1 MSNAPKIKVSGPVVELDGDEMTRVIWKLIKDMLILPYLDIRLDYYDLGIEHRDATDDQVT 60 MSNAPKIKVSGPVVELDGDEMTRVIWKLIKDMLILPYLDIRLDYYDLGIEHRDATDDQVT Sbjct 1 MSNAPKIKVSGPVVELDGDEMTRVIWKLIKDMLILPYLDIRLDYYDLGIEHRDATDDQVT 60 Query 61 IDAAYAIKKHGVGVKCATITPDEARVEEFNLKKMWLSPNGTIRNILGGTIFREPIVISNV 120 IDAAYAIKKHGVGVKCATITPDEARVEEFNLKKMWLSPNGTIRNILGGTIFREPIVISNV Sbjct 61 IDAAYAIKKHGVGVKCATITPDEARVEEFNLKKMWLSPNGTIRNILGGTIFREPIVISNV 120 Query 121 PRLVPGWTKPIVIGRHAFGDQYRATNFKVDQPGTVTLTFTPADGSAPIVHEMVSIPEDGG 180 PRLVPGWTKPIVIGRHAFGDQYRATNFKVDQPGTVTLTFTPADGSAPIVHEMVSIPEDGG Sbjct 121 PRLVPGWTKPIVIGRHAFGDQYRATNFKVDQPGTVTLTFTPADGSAPIVHEMVSIPEDGG 180 Query 181 VVLGMYNFKESIRDFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFERVYEEEFKA 240 VVLGMYNFKESIRDFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFERVYE EFKA Sbjct 181 VVLGMYNFKESIRDFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFERVYETEFKA 240 Query 241 QFEAAGLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMT 300 QFEAAGLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMT Sbjct 241 QFEAAGLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMT 300 Query 301 ADGKTVEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAH 360 ADGKTVEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAH Sbjct 301 ADGKTVEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAH 360 Query 361 KLESVVIATVESGKMTKDLAILIGPEQDWLNSEEFLDAIADNLEKELAN 409 KLESVVIATVESGKMTKDLAILIGPEQDWLNSEEFLDAIADNLEKELAN Sbjct 361 KLESVVIATVESGKMTKDLAILIGPEQDWLNSEEFLDAIADNLEKELAN 409 >gi|183981208|ref|YP_001849499.1| isocitrate dehydrogenase [NADP] Icd1 [Mycobacterium marinum M] gi|183174534|gb|ACC39644.1| isocitrate dehydrogenase [NADP] Icd1 [Mycobacterium marinum M] Length=408 Score = 776 bits (2003), Expect = 0.0, Method: Compositional matrix adjust. Identities = 369/408 (91%), Positives = 388/408 (96%), Gaps = 0/408 (0%) Query 1 MSNAPKIKVSGPVVELDGDEMTRVIWKLIKDMLILPYLDIRLDYYDLGIEHRDATDDQVT 60 MS PKI VSGPVVELDGDEMTRVIWKLIKD LILP+LD++L YYDLGIEHRD T+DQVT Sbjct 1 MSGEPKITVSGPVVELDGDEMTRVIWKLIKDRLILPHLDVKLLYYDLGIEHRDRTNDQVT 60 Query 61 IDAAYAIKKHGVGVKCATITPDEARVEEFNLKKMWLSPNGTIRNILGGTIFREPIVISNV 120 IDAAYAIKKHGVGVKCATITPDEARV EFNLKKMWLSPNGTIRNILGGTIFREPIVISNV Sbjct 61 IDAAYAIKKHGVGVKCATITPDEARVREFNLKKMWLSPNGTIRNILGGTIFREPIVISNV 120 Query 121 PRLVPGWTKPIVIGRHAFGDQYRATNFKVDQPGTVTLTFTPADGSAPIVHEMVSIPEDGG 180 PRLVPGWTKPIVIGRHAFGDQYRATNFKVD+PGTVTLTFTPADGS PIVHEMVSIPEDGG Sbjct 121 PRLVPGWTKPIVIGRHAFGDQYRATNFKVDRPGTVTLTFTPADGSEPIVHEMVSIPEDGG 180 Query 181 VVLGMYNFKESIRDFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFERVYEEEFKA 240 VV+GMYNF++SI+DFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEF+R+YEEEFK Sbjct 181 VVMGMYNFRKSIQDFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFQRIYEEEFKE 240 Query 241 QFEAAGLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMT 300 +F+A GLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMT Sbjct 241 RFDAEGLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMT 300 Query 301 ADGKTVEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAH 360 ADGKTVEAEAAHGTVTRHYRQYQAG+PTSTNPIASIFAWTRGL HRGKLD TPEV+ FA Sbjct 301 ADGKTVEAEAAHGTVTRHYRQYQAGQPTSTNPIASIFAWTRGLAHRGKLDNTPEVVQFAQ 360 Query 361 KLESVVIATVESGKMTKDLAILIGPEQDWLNSEEFLDAIADNLEKELA 408 LE VVI TVESGKMTKDLAILIGP+Q WLNSEEFL+AIA+NL K+L Sbjct 361 TLEDVVIKTVESGKMTKDLAILIGPQQAWLNSEEFLEAIAENLAKKLG 408 >gi|240169086|ref|ZP_04747745.1| isocitrate dehydrogenase [Mycobacterium kansasii ATCC 12478] Length=409 Score = 771 bits (1990), Expect = 0.0, Method: Compositional matrix adjust. Identities = 365/407 (90%), Positives = 387/407 (96%), Gaps = 0/407 (0%) Query 1 MSNAPKIKVSGPVVELDGDEMTRVIWKLIKDMLILPYLDIRLDYYDLGIEHRDATDDQVT 60 MS+ KIKV GP+VELDGDEMTRVIWKLIKD LILP+LDI L+YYDLGIEHRD T+DQVT Sbjct 1 MSSEAKIKVKGPLVELDGDEMTRVIWKLIKDKLILPHLDINLEYYDLGIEHRDQTNDQVT 60 Query 61 IDAAYAIKKHGVGVKCATITPDEARVEEFNLKKMWLSPNGTIRNILGGTIFREPIVISNV 120 IDAAYAIK+HGVGVKCATITPDEARV+EFNLKKMWLSPNGTIRNILGGTIFREPIVISNV Sbjct 61 IDAAYAIKRHGVGVKCATITPDEARVQEFNLKKMWLSPNGTIRNILGGTIFREPIVISNV 120 Query 121 PRLVPGWTKPIVIGRHAFGDQYRATNFKVDQPGTVTLTFTPADGSAPIVHEMVSIPEDGG 180 PRLVPGWTKPIVIGRHAFGDQYRATNFKV++PGTVTLTFTPADGS PIVHE+VSIPEDGG Sbjct 121 PRLVPGWTKPIVIGRHAFGDQYRATNFKVEKPGTVTLTFTPADGSQPIVHELVSIPEDGG 180 Query 181 VVLGMYNFKESIRDFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFERVYEEEFKA 240 VV+GMYNF++SI+DFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEF+R+YE EFK Sbjct 181 VVMGMYNFRKSIQDFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFQRIYETEFKD 240 Query 241 QFEAAGLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMT 300 +FEA GLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMT Sbjct 241 EFEAEGLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMT 300 Query 301 ADGKTVEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAH 360 ADGKTVEAEAAHGTVTRHYR YQAG+PTSTNPIASIFAWTRGL HRGKLD TP V++FA Sbjct 301 ADGKTVEAEAAHGTVTRHYRHYQAGQPTSTNPIASIFAWTRGLAHRGKLDNTPAVVEFAQ 360 Query 361 KLESVVIATVESGKMTKDLAILIGPEQDWLNSEEFLDAIADNLEKEL 407 LE VVI TVESGKMTKDLAILIGP+Q WLNSEEFLDAIA+NLEK L Sbjct 361 TLEDVVIKTVESGKMTKDLAILIGPQQGWLNSEEFLDAIAENLEKRL 407 >gi|254820256|ref|ZP_05225257.1| isocitrate dehydrogenase [Mycobacterium intracellulare ATCC 13950] Length=413 Score = 770 bits (1989), Expect = 0.0, Method: Compositional matrix adjust. Identities = 363/408 (89%), Positives = 387/408 (95%), Gaps = 0/408 (0%) Query 2 SNAPKIKVSGPVVELDGDEMTRVIWKLIKDMLILPYLDIRLDYYDLGIEHRDATDDQVTI 61 S KIKV G VVELDGDEMTRVIWKLIKD LILP+LDI LDYYDLGIEHRD TDDQVTI Sbjct 6 SKEAKIKVKGRVVELDGDEMTRVIWKLIKDQLILPHLDIDLDYYDLGIEHRDRTDDQVTI 65 Query 62 DAAYAIKKHGVGVKCATITPDEARVEEFNLKKMWLSPNGTIRNILGGTIFREPIVISNVP 121 DAAYAIKKHGVGVKCATITPDEARV EFNLKKMWLSPNGTIRNILGGTIFREPIVISNVP Sbjct 66 DAAYAIKKHGVGVKCATITPDEARVSEFNLKKMWLSPNGTIRNILGGTIFREPIVISNVP 125 Query 122 RLVPGWTKPIVIGRHAFGDQYRATNFKVDQPGTVTLTFTPADGSAPIVHEMVSIPEDGGV 181 RLVPGWTKPIVIGRHAFGDQYRATNFKVD+PGTV +TFTPADGS P+VHEMVS+P+DGGV Sbjct 126 RLVPGWTKPIVIGRHAFGDQYRATNFKVDKPGTVAITFTPADGSEPMVHEMVSLPDDGGV 185 Query 182 VLGMYNFKESIRDFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFERVYEEEFKAQ 241 V+GMYNFK+S+RDFARASF YGLNAKWPVYLSTKNTILKAYDGMFKDEF+R+Y+EEFK Q Sbjct 186 VMGMYNFKDSVRDFARASFKYGLNAKWPVYLSTKNTILKAYDGMFKDEFQRIYDEEFKEQ 245 Query 242 FEAAGLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMTA 301 FEA GLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSD +AQGYGSLGLMTSVLMTA Sbjct 246 FEAEGLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDAIAQGYGSLGLMTSVLMTA 305 Query 302 DGKTVEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAHK 361 DGKTVEAEAAHGTVTRH+RQYQAGKPTSTNPIASIFAWTRGL HRGKLD TPEV++FA Sbjct 306 DGKTVEAEAAHGTVTRHFRQYQAGKPTSTNPIASIFAWTRGLAHRGKLDDTPEVVEFAQT 365 Query 362 LESVVIATVESGKMTKDLAILIGPEQDWLNSEEFLDAIADNLEKELAN 409 LE+VV++TVESGKMTKDLAILIGP+Q+W SEEFLD+IA+NLEKELA+ Sbjct 366 LENVVVSTVESGKMTKDLAILIGPDQEWQQSEEFLDSIAENLEKELAS 413 >gi|41409553|ref|NP_962389.1| isocitrate dehydrogenase [Mycobacterium avium subsp. paratuberculosis K-10] gi|41398384|gb|AAS06005.1| Icd1 [Mycobacterium avium subsp. paratuberculosis K-10] gi|336459578|gb|EGO38513.1| isocitrate dehydrogenase, NADP-dependent [Mycobacterium avium subsp. paratuberculosis S397] Length=412 Score = 767 bits (1981), Expect = 0.0, Method: Compositional matrix adjust. Identities = 361/408 (89%), Positives = 384/408 (95%), Gaps = 0/408 (0%) Query 2 SNAPKIKVSGPVVELDGDEMTRVIWKLIKDMLILPYLDIRLDYYDLGIEHRDATDDQVTI 61 +N KIKV G VVELDGDEMTRVIWK+IK+ LILPYLDI LDYYDLGIEHRD TDDQVTI Sbjct 5 ANTSKIKVKGRVVELDGDEMTRVIWKMIKENLILPYLDIDLDYYDLGIEHRDRTDDQVTI 64 Query 62 DAAYAIKKHGVGVKCATITPDEARVEEFNLKKMWLSPNGTIRNILGGTIFREPIVISNVP 121 DAAYAIKKHGVGVKCATITPDEARV EFNLK+MWLSPNGTIRNILGGTIFREPIVISNVP Sbjct 65 DAAYAIKKHGVGVKCATITPDEARVREFNLKRMWLSPNGTIRNILGGTIFREPIVISNVP 124 Query 122 RLVPGWTKPIVIGRHAFGDQYRATNFKVDQPGTVTLTFTPADGSAPIVHEMVSIPEDGGV 181 RLVPGWTKPIVIGRHAFGDQYR+TNFKVD+PGTV +TFTPADGS PIVHEMVSIPEDGGV Sbjct 125 RLVPGWTKPIVIGRHAFGDQYRSTNFKVDKPGTVAITFTPADGSEPIVHEMVSIPEDGGV 184 Query 182 VLGMYNFKESIRDFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFERVYEEEFKAQ 241 V+GMYNF+ESIRDFARASF YGLNAKWPVYLSTKNTILKAYDGMFKDEF+R+Y+EEFK Q Sbjct 185 VMGMYNFRESIRDFARASFKYGLNAKWPVYLSTKNTILKAYDGMFKDEFQRIYDEEFKEQ 244 Query 242 FEAAGLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMTA 301 FEA GLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSD +AQGYGSLGLMTSVLMTA Sbjct 245 FEAEGLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDAIAQGYGSLGLMTSVLMTA 304 Query 302 DGKTVEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAHK 361 DGKTVEAEAAHGTVTRH+RQYQAGKPTSTNPIASIFAWTRGL HRGKLD TPEV++FA Sbjct 305 DGKTVEAEAAHGTVTRHFRQYQAGKPTSTNPIASIFAWTRGLAHRGKLDDTPEVVEFAQT 364 Query 362 LESVVIATVESGKMTKDLAILIGPEQDWLNSEEFLDAIADNLEKELAN 409 LE VV++TVESGKMTKDLAILIGP+Q W SEEFL++IA+NL +EL N Sbjct 365 LERVVVSTVESGKMTKDLAILIGPDQKWQQSEEFLNSIAENLRRELTN 412 >gi|118464587|ref|YP_883449.1| isocitrate dehydrogenase [Mycobacterium avium 104] gi|254776744|ref|ZP_05218260.1| isocitrate dehydrogenase [Mycobacterium avium subsp. avium ATCC 25291] gi|118165874|gb|ABK66771.1| isocitrate dehydrogenase, NADP-dependent [Mycobacterium avium 104] Length=412 Score = 766 bits (1979), Expect = 0.0, Method: Compositional matrix adjust. Identities = 361/408 (89%), Positives = 384/408 (95%), Gaps = 0/408 (0%) Query 2 SNAPKIKVSGPVVELDGDEMTRVIWKLIKDMLILPYLDIRLDYYDLGIEHRDATDDQVTI 61 +N KIKV G VVELDGDEMTRVIWK+IK+ LILPYLDI LDYYDLGIEHRD TDDQVTI Sbjct 5 ANTSKIKVKGRVVELDGDEMTRVIWKMIKENLILPYLDIDLDYYDLGIEHRDRTDDQVTI 64 Query 62 DAAYAIKKHGVGVKCATITPDEARVEEFNLKKMWLSPNGTIRNILGGTIFREPIVISNVP 121 DAAYAIKKHGVGVKCATITPDEARV EFNLK+MWLSPNGTIRNILGGTIFREPIVISNVP Sbjct 65 DAAYAIKKHGVGVKCATITPDEARVREFNLKRMWLSPNGTIRNILGGTIFREPIVISNVP 124 Query 122 RLVPGWTKPIVIGRHAFGDQYRATNFKVDQPGTVTLTFTPADGSAPIVHEMVSIPEDGGV 181 RLVPGW+KPIVIGRHAFGDQYR+TNFKVD+PGTV +TFTPADGS PIVHEMVSIPEDGGV Sbjct 125 RLVPGWSKPIVIGRHAFGDQYRSTNFKVDKPGTVAITFTPADGSEPIVHEMVSIPEDGGV 184 Query 182 VLGMYNFKESIRDFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFERVYEEEFKAQ 241 V+GMYNF+ESIRDFARASF YGLNAKWPVYLSTKNTILKAYDGMFKDEF+R+Y+EEFK Q Sbjct 185 VMGMYNFRESIRDFARASFKYGLNAKWPVYLSTKNTILKAYDGMFKDEFQRIYDEEFKEQ 244 Query 242 FEAAGLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMTA 301 FEA GLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSD +AQGYGSLGLMTSVLMTA Sbjct 245 FEAEGLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDAIAQGYGSLGLMTSVLMTA 304 Query 302 DGKTVEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAHK 361 DGKTVEAEAAHGTVTRH+RQYQAGKPTSTNPIASIFAWTRGL HRGKLD TPEVI+FA Sbjct 305 DGKTVEAEAAHGTVTRHFRQYQAGKPTSTNPIASIFAWTRGLAHRGKLDDTPEVIEFAQT 364 Query 362 LESVVIATVESGKMTKDLAILIGPEQDWLNSEEFLDAIADNLEKELAN 409 LE VV++TVESGKMTKDLAILIGP+Q W SEEFL++IA+NL +EL N Sbjct 365 LERVVVSTVESGKMTKDLAILIGPDQKWQQSEEFLNSIAENLRRELTN 412 >gi|296168845|ref|ZP_06850517.1| isocitrate dehydrogenase [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295896462|gb|EFG76112.1| isocitrate dehydrogenase [Mycobacterium parascrofulaceum ATCC BAA-614] Length=407 Score = 766 bits (1977), Expect = 0.0, Method: Compositional matrix adjust. Identities = 363/409 (89%), Positives = 389/409 (96%), Gaps = 2/409 (0%) Query 1 MSNAPKIKVSGPVVELDGDEMTRVIWKLIKDMLILPYLDIRLDYYDLGIEHRDATDDQVT 60 MSN K KV GPVVELDGDEMTRVIWK IKDMLILP+LDI LDYYDLGIE+RD T+DQVT Sbjct 1 MSN--KTKVKGPVVELDGDEMTRVIWKFIKDMLILPHLDINLDYYDLGIENRDRTNDQVT 58 Query 61 IDAAYAIKKHGVGVKCATITPDEARVEEFNLKKMWLSPNGTIRNILGGTIFREPIVISNV 120 IDAAYAIK+HGVGVKCATITPDEARV EFNLKKMWLSPNGTIRNILGGTIFREPIVISNV Sbjct 59 IDAAYAIKRHGVGVKCATITPDEARVHEFNLKKMWLSPNGTIRNILGGTIFREPIVISNV 118 Query 121 PRLVPGWTKPIVIGRHAFGDQYRATNFKVDQPGTVTLTFTPADGSAPIVHEMVSIPEDGG 180 PRLVPGWTKPIVIGRHAFGDQYRATNFKVD+PGTV++TFTP+DGS P+VHE+VSIP+DGG Sbjct 119 PRLVPGWTKPIVIGRHAFGDQYRATNFKVDKPGTVSITFTPSDGSEPMVHEVVSIPDDGG 178 Query 181 VVLGMYNFKESIRDFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFERVYEEEFKA 240 VV+GMYNFKES+RDFARAS +YGLNAKWPVYLSTKNTILKAYDGMFKDEF+R+Y+EEFK Sbjct 179 VVMGMYNFKESVRDFARASLAYGLNAKWPVYLSTKNTILKAYDGMFKDEFQRIYDEEFKD 238 Query 241 QFEAAGLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMT 300 QFEA GLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSD VAQGYGSLGLMTSVLMT Sbjct 239 QFEAEGLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDLVAQGYGSLGLMTSVLMT 298 Query 301 ADGKTVEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAH 360 ADGKTVEAEAAHGTVTRH+RQYQAGKPTSTNPIASIFAWTRGLQHRGKLD TPEVI+FA Sbjct 299 ADGKTVEAEAAHGTVTRHFRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDDTPEVIEFAQ 358 Query 361 KLESVVIATVESGKMTKDLAILIGPEQDWLNSEEFLDAIADNLEKELAN 409 LE VV+ TVESGKMTKDLAILIGP+Q+W SEEFL++IA+NLEK+LAN Sbjct 359 TLEDVVVGTVESGKMTKDLAILIGPDQEWQQSEEFLNSIAENLEKKLAN 407 >gi|342861559|ref|ZP_08718206.1| isocitrate dehydrogenase [Mycobacterium colombiense CECT 3035] gi|342131048|gb|EGT84337.1| isocitrate dehydrogenase [Mycobacterium colombiense CECT 3035] Length=409 Score = 765 bits (1975), Expect = 0.0, Method: Compositional matrix adjust. Identities = 363/409 (89%), Positives = 387/409 (95%), Gaps = 0/409 (0%) Query 1 MSNAPKIKVSGPVVELDGDEMTRVIWKLIKDMLILPYLDIRLDYYDLGIEHRDATDDQVT 60 M+ KIKV G VVELDGDEMTRVIWK IKDMLILP+LDI LDYYDLGIEHRD TDDQVT Sbjct 1 MAGEGKIKVKGRVVELDGDEMTRVIWKFIKDMLILPHLDIDLDYYDLGIEHRDRTDDQVT 60 Query 61 IDAAYAIKKHGVGVKCATITPDEARVEEFNLKKMWLSPNGTIRNILGGTIFREPIVISNV 120 IDAAYAIKKHGVGVKCATITPDEARV+EFNLKKMWLSPNGTIRNILGGTIFREPIVISNV Sbjct 61 IDAAYAIKKHGVGVKCATITPDEARVQEFNLKKMWLSPNGTIRNILGGTIFREPIVISNV 120 Query 121 PRLVPGWTKPIVIGRHAFGDQYRATNFKVDQPGTVTLTFTPADGSAPIVHEMVSIPEDGG 180 PRLVPGWTKPIVIGRHAFGDQYR+TNFKVD+PGTV +TFTPADGS P+VHE+VSIPEDGG Sbjct 121 PRLVPGWTKPIVIGRHAFGDQYRSTNFKVDKPGTVAITFTPADGSEPMVHEVVSIPEDGG 180 Query 181 VVLGMYNFKESIRDFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFERVYEEEFKA 240 VV+GMYNFK+SIRDFARAS YGLNAKWPVYLSTKNTILKAYDGMFKDEF+RVY+EEFK Sbjct 181 VVMGMYNFKDSIRDFARASLKYGLNAKWPVYLSTKNTILKAYDGMFKDEFQRVYDEEFKD 240 Query 241 QFEAAGLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMT 300 QFEA GLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSD VAQGYGSLGLMTSVLMT Sbjct 241 QFEAEGLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDLVAQGYGSLGLMTSVLMT 300 Query 301 ADGKTVEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAH 360 ADGKTVEAEAAHGTVTRH+RQYQAGKPTSTNPIASIFAWTRGL HRGKLD TPEVI+FA Sbjct 301 ADGKTVEAEAAHGTVTRHFRQYQAGKPTSTNPIASIFAWTRGLAHRGKLDDTPEVIEFAQ 360 Query 361 KLESVVIATVESGKMTKDLAILIGPEQDWLNSEEFLDAIADNLEKELAN 409 LE+VV++TVESGKMTKDLAILIGP+Q W +EEFL++IA+NLEK+LA+ Sbjct 361 TLENVVVSTVESGKMTKDLAILIGPDQQWQQTEEFLNSIAENLEKQLAS 409 >gi|333921640|ref|YP_004495221.1| isocitrate dehydrogenase [NADP] [Amycolicicoccus subflavus DQS3-9A1] gi|333483861|gb|AEF42421.1| Isocitrate dehydrogenase [NADP] [Amycolicicoccus subflavus DQS3-9A1] Length=407 Score = 701 bits (1809), Expect = 0.0, Method: Compositional matrix adjust. Identities = 327/399 (82%), Positives = 366/399 (92%), Gaps = 0/399 (0%) Query 6 KIKVSGPVVELDGDEMTRVIWKLIKDMLILPYLDIRLDYYDLGIEHRDATDDQVTIDAAY 65 KIKV G VVELDGDEMTR+IW+ IKD LI PYLD+ L+YYDLG+E+RDATDDQVT+DAA Sbjct 3 KIKVEGTVVELDGDEMTRIIWQFIKDKLIHPYLDVNLEYYDLGMENRDATDDQVTVDAAN 62 Query 66 AIKKHGVGVKCATITPDEARVEEFNLKKMWLSPNGTIRNILGGTIFREPIVISNVPRLVP 125 AIKKHG GVKCATITPDEARVEEF LKKMW SPNGTIRNILGGTIFR PI+ISN+PRLVP Sbjct 63 AIKKHGAGVKCATITPDEARVEEFGLKKMWRSPNGTIRNILGGTIFRAPIIISNIPRLVP 122 Query 126 GWTKPIVIGRHAFGDQYRATNFKVDQPGTVTLTFTPADGSAPIVHEMVSIPEDGGVVLGM 185 GWTKP+V+GRHAFGDQYRAT+FKV Q GTVTLTFTP DGS PI HE+V +PEDGGV+LGM Sbjct 123 GWTKPVVVGRHAFGDQYRATDFKVHQAGTVTLTFTPEDGSEPIQHEVVKMPEDGGVILGM 182 Query 186 YNFKESIRDFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFERVYEEEFKAQFEAA 245 YNFK+SI+DFARAS +YGL +PVYLSTKNTILKAYDGMFKDEF+RVYEEEFK++F+AA Sbjct 183 YNFKKSIQDFARASLAYGLQQNYPVYLSTKNTILKAYDGMFKDEFQRVYEEEFKSEFDAA 242 Query 246 GLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMTADGKT 305 GLTYEHRLIDDMVA+ LKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMT DGKT Sbjct 243 GLTYEHRLIDDMVASALKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMTPDGKT 302 Query 306 VEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAHKLESV 365 VEAEAAHGTVTRH+R +Q GKPTSTNPIASIFAWTRGL+HRGKLD TP V++FAH+LE V Sbjct 303 VEAEAAHGTVTRHFRMHQQGKPTSTNPIASIFAWTRGLEHRGKLDNTPAVVEFAHQLEDV 362 Query 366 VIATVESGKMTKDLAILIGPEQDWLNSEEFLDAIADNLE 404 VI TVESG+MTKDLA+L+G +Q +L++EEFL A+ DNL+ Sbjct 363 VIKTVESGQMTKDLAVLVGGDQGYLSTEEFLGALDDNLQ 401 >gi|312140780|ref|YP_004008116.1| nADP-dependent isocitrate dehydrogenase [Rhodococcus equi 103S] gi|325675580|ref|ZP_08155264.1| isocitrate dehydrogenase [Rhodococcus equi ATCC 33707] gi|311890119|emb|CBH49437.1| NADP-dependent isocitrate dehydrogenase [Rhodococcus equi 103S] gi|325553551|gb|EGD23229.1| isocitrate dehydrogenase [Rhodococcus equi ATCC 33707] Length=405 Score = 694 bits (1792), Expect = 0.0, Method: Compositional matrix adjust. Identities = 325/403 (81%), Positives = 364/403 (91%), Gaps = 0/403 (0%) Query 6 KIKVSGPVVELDGDEMTRVIWKLIKDMLILPYLDIRLDYYDLGIEHRDATDDQVTIDAAY 65 KIKV G VVELDGDEMTR+IW+ IKD LI PYLD+ L+YYDLGIEHRDATDDQVTIDAA Sbjct 3 KIKVEGKVVELDGDEMTRIIWQFIKDKLIHPYLDVDLEYYDLGIEHRDATDDQVTIDAAE 62 Query 66 AIKKHGVGVKCATITPDEARVEEFNLKKMWLSPNGTIRNILGGTIFREPIVISNVPRLVP 125 AIKKHGVGVKCATITPDEARVEEF LKKMW SPNGTIRNILGGTIFR PI+ISNVPRLVP Sbjct 63 AIKKHGVGVKCATITPDEARVEEFGLKKMWRSPNGTIRNILGGTIFRAPILISNVPRLVP 122 Query 126 GWTKPIVIGRHAFGDQYRATNFKVDQPGTVTLTFTPADGSAPIVHEMVSIPEDGGVVLGM 185 GWTKP+++GRHAFGDQYRAT+FK GTVT+T+TP DGS PI HE+ +PEDGGVV+GM Sbjct 123 GWTKPVIVGRHAFGDQYRATDFKAPGAGTVTITYTPDDGSEPIQHEVCRLPEDGGVVMGM 182 Query 186 YNFKESIRDFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFERVYEEEFKAQFEAA 245 YN+K+SI+DFARAS SYGL +PVYLSTKNTILKAYDGMFKDEF+R+YE+EFKA+F+AA Sbjct 183 YNYKKSIQDFARASLSYGLQQNYPVYLSTKNTILKAYDGMFKDEFQRIYEDEFKAEFDAA 242 Query 246 GLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMTADGKT 305 GL YEHRLIDDMVA+ LKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMT DG+T Sbjct 243 GLHYEHRLIDDMVASSLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMTPDGRT 302 Query 306 VEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAHKLESV 365 VEAEAAHGTVTRHYRQ+Q GKPTSTNPIASIFAWTRGL+HRGKLD TPE+I+FA +LE V Sbjct 303 VEAEAAHGTVTRHYRQHQQGKPTSTNPIASIFAWTRGLEHRGKLDNTPELIEFAQQLEDV 362 Query 366 VIATVESGKMTKDLAILIGPEQDWLNSEEFLDAIADNLEKELA 408 VI TVE+G+MTKDLA+L+GP+Q W +EEFL + +NL+K A Sbjct 363 VIKTVENGQMTKDLALLVGPDQAWQTTEEFLATLDENLQKARA 405 >gi|54022890|ref|YP_117132.1| isocitrate dehydrogenase [Nocardia farcinica IFM 10152] gi|54014398|dbj|BAD55768.1| putative isocitrate/isopropylmalate dehydrogenase [Nocardia farcinica IFM 10152] Length=405 Score = 684 bits (1764), Expect = 0.0, Method: Compositional matrix adjust. Identities = 321/402 (80%), Positives = 360/402 (90%), Gaps = 0/402 (0%) Query 6 KIKVSGPVVELDGDEMTRVIWKLIKDMLILPYLDIRLDYYDLGIEHRDATDDQVTIDAAY 65 KIKV G VVELDGDEMTR+IW+ IKD LI PYLD+ L+YYDLGIE+RD TDDQVT+DAA Sbjct 3 KIKVEGTVVELDGDEMTRIIWQFIKDKLIHPYLDVNLEYYDLGIEYRDKTDDQVTVDAAE 62 Query 66 AIKKHGVGVKCATITPDEARVEEFNLKKMWLSPNGTIRNILGGTIFREPIVISNVPRLVP 125 AIK+HGVGVKCATITPDEARV+EF LKKMW SPNGTIRNILGGTIFR PI+ISN+PRLVP Sbjct 63 AIKRHGVGVKCATITPDEARVKEFGLKKMWRSPNGTIRNILGGTIFRAPIIISNIPRLVP 122 Query 126 GWTKPIVIGRHAFGDQYRATNFKVDQPGTVTLTFTPADGSAPIVHEMVSIPEDGGVVLGM 185 GWTKPI+IGRHAFGDQYRAT+FKV Q GTVTLTFTP DGS PIVHE+V +PEDGGVV+GM Sbjct 123 GWTKPIIIGRHAFGDQYRATDFKVFQGGTVTLTFTPDDGSEPIVHEVVKMPEDGGVVMGM 182 Query 186 YNFKESIRDFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFERVYEEEFKAQFEAA 245 YNFK+SI DFARASF+YGL +PVY+STKNTILKAYDGMFKD F+ +++ EFK+QF+AA Sbjct 183 YNFKKSIEDFARASFNYGLQQNYPVYMSTKNTILKAYDGMFKDTFQEIFDTEFKSQFDAA 242 Query 246 GLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMTADGKT 305 GLTYEHRLIDDMVA+ +KWEGGYVWACKNYDGDVQSDTVAQG+GSLGLMTSVL+T DGKT Sbjct 243 GLTYEHRLIDDMVASSMKWEGGYVWACKNYDGDVQSDTVAQGFGSLGLMTSVLLTPDGKT 302 Query 306 VEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAHKLESV 365 EAEAAHGTVTRHYRQ+Q GKPTSTNPIASIFAWTRGL+HRGKLD TPEVI FA LE V Sbjct 303 CEAEAAHGTVTRHYRQHQQGKPTSTNPIASIFAWTRGLEHRGKLDNTPEVIGFAQTLEDV 362 Query 366 VIATVESGKMTKDLAILIGPEQDWLNSEEFLDAIADNLEKEL 407 VI TVE G+MTKDLA+L+G +Q +L +EEFL A+ NL + L Sbjct 363 VIKTVEGGQMTKDLALLVGGDQGYLTTEEFLGALDTNLARAL 404 >gi|336320051|ref|YP_004600019.1| isocitrate dehydrogenase, NADP-dependent [Cellvibrio gilvus ATCC 13127] gi|336103632|gb|AEI11451.1| isocitrate dehydrogenase, NADP-dependent [Cellvibrio gilvus ATCC 13127] Length=405 Score = 680 bits (1754), Expect = 0.0, Method: Compositional matrix adjust. Identities = 324/403 (81%), Positives = 356/403 (89%), Gaps = 0/403 (0%) Query 6 KIKVSGPVVELDGDEMTRVIWKLIKDMLILPYLDIRLDYYDLGIEHRDATDDQVTIDAAY 65 KIKV GPVVELDGDEMTR+IW+ IKD LI PYLDI L YYDL IE+RDATDDQVTIDAA+ Sbjct 3 KIKVVGPVVELDGDEMTRIIWQFIKDRLIHPYLDIDLRYYDLSIENRDATDDQVTIDAAH 62 Query 66 AIKKHGVGVKCATITPDEARVEEFNLKKMWLSPNGTIRNILGGTIFREPIVISNVPRLVP 125 AIK+HGVGVKCATITPDEARVEEF LKKMW+SPNGTIRNILGG +FREPI+ISN+PRLVP Sbjct 63 AIKEHGVGVKCATITPDEARVEEFGLKKMWVSPNGTIRNILGGVVFREPIIISNIPRLVP 122 Query 126 GWTKPIVIGRHAFGDQYRATNFKVDQPGTVTLTFTPADGSAPIVHEMVSIPEDGGVVLGM 185 GW KPI+IGRHA GDQY+ATNFKV GT+TLTFTPADGS PI ++V+ P+ GGV +GM Sbjct 123 GWNKPIIIGRHAHGDQYKATNFKVAGAGTLTLTFTPADGSEPIQQQVVTYPDGGGVAMGM 182 Query 186 YNFKESIRDFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFERVYEEEFKAQFEAA 245 YNF +SIRDFARASF+YGL +PVYLSTKNTILKAYDG FKD F+ V++ EFKA F+AA Sbjct 183 YNFNDSIRDFARASFAYGLQRGYPVYLSTKNTILKAYDGAFKDIFQEVFDAEFKADFDAA 242 Query 246 GLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMTADGKT 305 GLTYEHRLIDDMVAA +KWEGGYVWACKNYDGDVQSDTVAQG+GSLGLMTSVLMT DGKT Sbjct 243 GLTYEHRLIDDMVAAAMKWEGGYVWACKNYDGDVQSDTVAQGFGSLGLMTSVLMTPDGKT 302 Query 306 VEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAHKLESV 365 VEAEAAHGTVTRHYRQ+QAGKPTSTNPIASIFAWT GL+HRGKLD TPEV FA LE V Sbjct 303 VEAEAAHGTVTRHYRQHQAGKPTSTNPIASIFAWTGGLKHRGKLDATPEVTQFAQTLEDV 362 Query 366 VIATVESGKMTKDLAILIGPEQDWLNSEEFLDAIADNLEKELA 408 VI TVESGKMTKDLA LIGP+Q WL +EEFL A+ +NL LA Sbjct 363 VITTVESGKMTKDLAQLIGPDQAWLTTEEFLAALDENLAARLA 405 >gi|229489415|ref|ZP_04383278.1| isocitrate dehydrogenase, NADP-dependent [Rhodococcus erythropolis SK121] gi|229323512|gb|EEN89270.1| isocitrate dehydrogenase, NADP-dependent [Rhodococcus erythropolis SK121] Length=407 Score = 679 bits (1751), Expect = 0.0, Method: Compositional matrix adjust. Identities = 322/403 (80%), Positives = 357/403 (89%), Gaps = 0/403 (0%) Query 6 KIKVSGPVVELDGDEMTRVIWKLIKDMLILPYLDIRLDYYDLGIEHRDATDDQVTIDAAY 65 KIKV G VVELDGDEMTR+IW+ IKD LI PYLD+ L+YYDLGIE+RD TDDQVTIDAA+ Sbjct 3 KIKVEGTVVELDGDEMTRIIWQFIKDKLIHPYLDVNLEYYDLGIEYRDETDDQVTIDAAH 62 Query 66 AIKKHGVGVKCATITPDEARVEEFNLKKMWLSPNGTIRNILGGTIFREPIVISNVPRLVP 125 AI+KHGVGVKCATITPDEARVEEF LKKMW SPNGTIRNILGGTIFR PI+ISNVPRLVP Sbjct 63 AIQKHGVGVKCATITPDEARVEEFGLKKMWRSPNGTIRNILGGTIFRAPIIISNVPRLVP 122 Query 126 GWTKPIVIGRHAFGDQYRATNFKVDQPGTVTLTFTPADGSAPIVHEMVSIPEDGGVVLGM 185 GWTKPI+IGRHAFGDQYRAT+FKV PG V +T+TP DGSAPI HE+V+ PE+GGVV G Sbjct 123 GWTKPIIIGRHAFGDQYRATDFKVPGPGKVMITYTPEDGSAPIEHELVNFPEEGGVVQGQ 182 Query 186 YNFKESIRDFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFERVYEEEFKAQFEAA 245 YNF SIRDFARAS +YGL +PVYLSTKNTILKAYDG FKD F+ VYE EFKA+F+AA Sbjct 183 YNFTTSIRDFARASLTYGLQQNYPVYLSTKNTILKAYDGAFKDIFQHVYETEFKAEFDAA 242 Query 246 GLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMTADGKT 305 GLTYEHRLIDDMVA+ LKWEGGYVWACKNYDGDVQSDTVAQG+GSLGLMTSVL+T DGKT Sbjct 243 GLTYEHRLIDDMVASALKWEGGYVWACKNYDGDVQSDTVAQGFGSLGLMTSVLLTPDGKT 302 Query 306 VEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAHKLESV 365 EAEAAHGTVTRHYRQ+Q GKPTSTNPIASIFAWTRGL+HRGKLD TPEVI FA LE V Sbjct 303 CEAEAAHGTVTRHYRQHQQGKPTSTNPIASIFAWTRGLEHRGKLDSTPEVIGFAQALEDV 362 Query 366 VIATVESGKMTKDLAILIGPEQDWLNSEEFLDAIADNLEKELA 408 VI TVESG+MTKDL++L+G +Q +L +EEFL A+ NL+K +A Sbjct 363 VIKTVESGQMTKDLSMLVGGDQGYLTTEEFLGALDVNLQKAMA 405 >gi|317508482|ref|ZP_07966150.1| isocitrate dehydrogenase [Segniliparus rugosus ATCC BAA-974] gi|316253230|gb|EFV12632.1| isocitrate dehydrogenase [Segniliparus rugosus ATCC BAA-974] Length=405 Score = 678 bits (1749), Expect = 0.0, Method: Compositional matrix adjust. Identities = 319/403 (80%), Positives = 357/403 (89%), Gaps = 0/403 (0%) Query 6 KIKVSGPVVELDGDEMTRVIWKLIKDMLILPYLDIRLDYYDLGIEHRDATDDQVTIDAAY 65 KIKV G VVELDGDEMTR+IWK IKD LI PYLDI L+YYDLGIEHRDATDDQVT++AA Sbjct 3 KIKVEGVVVELDGDEMTRIIWKFIKDKLIYPYLDIDLEYYDLGIEHRDATDDQVTVEAAE 62 Query 66 AIKKHGVGVKCATITPDEARVEEFNLKKMWLSPNGTIRNILGGTIFREPIVISNVPRLVP 125 AIK+HGVGVKCATITPDEARV EF LKKMW SPNGTIRNILGGTIFR PI+I +VPRLVP Sbjct 63 AIKRHGVGVKCATITPDEARVVEFGLKKMWKSPNGTIRNILGGTIFRAPIIIKSVPRLVP 122 Query 126 GWTKPIVIGRHAFGDQYRATNFKVDQPGTVTLTFTPADGSAPIVHEMVSIPEDGGVVLGM 185 GWTKPI+IGRHAFGDQYRAT+FKV PGTVT+T+TP+DG PI HE+V +PE GGVV+GM Sbjct 123 GWTKPIIIGRHAFGDQYRATDFKVPGPGTVTITYTPSDGGEPIQHEVVKMPEQGGVVMGM 182 Query 186 YNFKESIRDFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFERVYEEEFKAQFEAA 245 YNF +SI DFARAS +YGL +PVYLSTKNTILKAYDG+FKD F+ VYE+EFKA+F+AA Sbjct 183 YNFTQSIVDFARASLNYGLQQNYPVYLSTKNTILKAYDGLFKDVFQEVYEKEFKAEFDAA 242 Query 246 GLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMTADGKT 305 GLTYEHRLIDDMVA+ LKWEGGYVWACKNYDGDVQSDTVAQG+GSLGLMTSVL+T DGK Sbjct 243 GLTYEHRLIDDMVASALKWEGGYVWACKNYDGDVQSDTVAQGFGSLGLMTSVLLTPDGKI 302 Query 306 VEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAHKLESV 365 E+EAAHGTVTRHYRQYQ GKPTSTNP+ASIFAWTRGL HRG+LDGT EV FAHKLE V Sbjct 303 CESEAAHGTVTRHYRQYQQGKPTSTNPVASIFAWTRGLAHRGRLDGTREVEGFAHKLEDV 362 Query 366 VIATVESGKMTKDLAILIGPEQDWLNSEEFLDAIADNLEKELA 408 V+ T+E GKMTKDLA+L+G +Q WL +EEFL + +NL+ ELA Sbjct 363 VVRTIEDGKMTKDLALLVGGDQGWLTTEEFLSVLDENLQAELA 405 >gi|296130365|ref|YP_003637615.1| isocitrate dehydrogenase, NADP-dependent [Cellulomonas flavigena DSM 20109] gi|296022180|gb|ADG75416.1| isocitrate dehydrogenase, NADP-dependent [Cellulomonas flavigena DSM 20109] Length=422 Score = 678 bits (1749), Expect = 0.0, Method: Compositional matrix adjust. Identities = 321/403 (80%), Positives = 356/403 (89%), Gaps = 0/403 (0%) Query 6 KIKVSGPVVELDGDEMTRVIWKLIKDMLILPYLDIRLDYYDLGIEHRDATDDQVTIDAAY 65 KIKV GPVVELDGDEMTR+IW+ IKD LI PYLD+ L YYDL I++RDATDDQVTIDAA+ Sbjct 20 KIKVVGPVVELDGDEMTRIIWQFIKDRLIHPYLDVDLRYYDLSIQNRDATDDQVTIDAAH 79 Query 66 AIKKHGVGVKCATITPDEARVEEFNLKKMWLSPNGTIRNILGGTIFREPIVISNVPRLVP 125 AIK+HGVGVKCATITPDEARVEEF LKKMW+SPNGTIRNILGG +FREPI+ISN+PRLVP Sbjct 80 AIKEHGVGVKCATITPDEARVEEFGLKKMWVSPNGTIRNILGGVVFREPIIISNIPRLVP 139 Query 126 GWTKPIVIGRHAFGDQYRATNFKVDQPGTVTLTFTPADGSAPIVHEMVSIPEDGGVVLGM 185 GW KPI+IGRHA GDQY+ATNFKV GT+TLT+TPADGS PI E+V+ PE GGV +GM Sbjct 140 GWNKPIIIGRHAHGDQYKATNFKVPGAGTLTLTYTPADGSEPIHQEVVTYPEAGGVAMGM 199 Query 186 YNFKESIRDFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFERVYEEEFKAQFEAA 245 YNF ESIRDFARASF+YGL +PVYLSTKNTILKAYDG FKD F+ V++ EFK QF+AA Sbjct 200 YNFNESIRDFARASFAYGLQRGYPVYLSTKNTILKAYDGAFKDIFQEVFDAEFKEQFDAA 259 Query 246 GLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMTADGKT 305 GLTYEHRLIDDMVAA +KWEGGYVWACKNYDGDVQSDTVAQG+GSLGLMTSVLMT DG+T Sbjct 260 GLTYEHRLIDDMVAAAMKWEGGYVWACKNYDGDVQSDTVAQGFGSLGLMTSVLMTPDGRT 319 Query 306 VEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAHKLESV 365 VEAEAAHGTVTRHYRQ+QAGKPTSTNPIASIFAWT GL+HRGKLDGTPEV FA LE V Sbjct 320 VEAEAAHGTVTRHYRQHQAGKPTSTNPIASIFAWTGGLKHRGKLDGTPEVTQFAETLEDV 379 Query 366 VIATVESGKMTKDLAILIGPEQDWLNSEEFLDAIADNLEKELA 408 VI TVESGKMTKDLA+L+G +Q WL +EEFL A+ +NL L Sbjct 380 VITTVESGKMTKDLALLVGKDQPWLTTEEFLAALDENLAARLG 422 >gi|226305492|ref|YP_002765452.1| NADP-dependent isocitrate dehydrogenase [Rhodococcus erythropolis PR4] gi|226184609|dbj|BAH32713.1| NADP-dependent isocitrate dehydrogenase [Rhodococcus erythropolis PR4] Length=407 Score = 677 bits (1748), Expect = 0.0, Method: Compositional matrix adjust. Identities = 321/403 (80%), Positives = 357/403 (89%), Gaps = 0/403 (0%) Query 6 KIKVSGPVVELDGDEMTRVIWKLIKDMLILPYLDIRLDYYDLGIEHRDATDDQVTIDAAY 65 KIKV G VVELDGDEMTR+IW+ IKD LI PYLD+ L+YYDLGIE+RD TDDQVTIDAA+ Sbjct 3 KIKVEGTVVELDGDEMTRIIWQFIKDKLIHPYLDVNLEYYDLGIEYRDETDDQVTIDAAH 62 Query 66 AIKKHGVGVKCATITPDEARVEEFNLKKMWLSPNGTIRNILGGTIFREPIVISNVPRLVP 125 AI+KHGVGVKCATITPDEARVEEF LKKMW SPNGTIRNILGGTIFR PI+ISNVPRLVP Sbjct 63 AIQKHGVGVKCATITPDEARVEEFGLKKMWRSPNGTIRNILGGTIFRAPIIISNVPRLVP 122 Query 126 GWTKPIVIGRHAFGDQYRATNFKVDQPGTVTLTFTPADGSAPIVHEMVSIPEDGGVVLGM 185 GWTKPI+IGRHAFGDQYRAT+FKV PG V +T+TP DGSAPI HE+V+ PE+GGVV G Sbjct 123 GWTKPIIIGRHAFGDQYRATDFKVPGPGKVMITYTPEDGSAPIEHELVNFPEEGGVVQGQ 182 Query 186 YNFKESIRDFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFERVYEEEFKAQFEAA 245 YNF SIRDFARAS +YGL +PVYLSTKNTILKAYDG FKD F+ VYE EFKA+F+AA Sbjct 183 YNFTTSIRDFARASLTYGLQQNYPVYLSTKNTILKAYDGAFKDIFQHVYETEFKAEFDAA 242 Query 246 GLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMTADGKT 305 GLTYEHRLIDDMVA+ LKWEGGYVWACKNYDGDVQSDTVAQG+GSLGLMTSVL+T DG+T Sbjct 243 GLTYEHRLIDDMVASALKWEGGYVWACKNYDGDVQSDTVAQGFGSLGLMTSVLLTPDGRT 302 Query 306 VEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAHKLESV 365 EAEAAHGTVTRHYRQ+Q GKPTSTNPIASIFAWTRGL+HRGKLD TPEVI FA LE V Sbjct 303 CEAEAAHGTVTRHYRQHQQGKPTSTNPIASIFAWTRGLEHRGKLDSTPEVIGFAQALEDV 362 Query 366 VIATVESGKMTKDLAILIGPEQDWLNSEEFLDAIADNLEKELA 408 VI TVESG+MTKDL++L+G +Q +L +EEFL A+ NL+K +A Sbjct 363 VIKTVESGQMTKDLSMLVGGDQGYLTTEEFLGALDVNLQKAMA 405 >gi|332669636|ref|YP_004452644.1| NADP-dependent isocitrate dehydrogenase [Cellulomonas fimi ATCC 484] gi|332338674|gb|AEE45257.1| isocitrate dehydrogenase, NADP-dependent [Cellulomonas fimi ATCC 484] Length=405 Score = 677 bits (1747), Expect = 0.0, Method: Compositional matrix adjust. Identities = 323/403 (81%), Positives = 352/403 (88%), Gaps = 0/403 (0%) Query 6 KIKVSGPVVELDGDEMTRVIWKLIKDMLILPYLDIRLDYYDLGIEHRDATDDQVTIDAAY 65 KIKV GPVVELDGDEMTR+IW+ IKD LI PYLDI L YYDL I++RDATDDQVTIDAA+ Sbjct 3 KIKVVGPVVELDGDEMTRIIWQFIKDRLIHPYLDIDLRYYDLSIQNRDATDDQVTIDAAH 62 Query 66 AIKKHGVGVKCATITPDEARVEEFNLKKMWLSPNGTIRNILGGTIFREPIVISNVPRLVP 125 AIK+HGVGVKCATITPDEARVEEF LKKMW+SPNGTIRNILGG +FREPI+ISN+PRLVP Sbjct 63 AIKEHGVGVKCATITPDEARVEEFGLKKMWVSPNGTIRNILGGVVFREPIIISNIPRLVP 122 Query 126 GWTKPIVIGRHAFGDQYRATNFKVDQPGTVTLTFTPADGSAPIVHEMVSIPEDGGVVLGM 185 GW KPI+IGRHA GDQY+ATNFKV GT+TLTFTPADGS PI ++V+ PE GGV +GM Sbjct 123 GWNKPIIIGRHAHGDQYKATNFKVAGAGTLTLTFTPADGSEPIQQQVVTYPETGGVAMGM 182 Query 186 YNFKESIRDFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFERVYEEEFKAQFEAA 245 YNF ESIRDFARASF+YGL +PVYLSTKNTILKAYDG FKD F+ V++EEF A F Sbjct 183 YNFNESIRDFARASFAYGLQRGYPVYLSTKNTILKAYDGQFKDIFQEVFDEEFAAAFAEK 242 Query 246 GLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMTADGKT 305 GLTYEHRLIDD VAA +KWEGGYVWACKNYDGDVQSDTVAQG+GSLGLMTSVLMT DGKT Sbjct 243 GLTYEHRLIDDTVAAAMKWEGGYVWACKNYDGDVQSDTVAQGFGSLGLMTSVLMTPDGKT 302 Query 306 VEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAHKLESV 365 VEAEAAHGTVTRHYRQ+Q GKPTSTNPIASIFAWT GL+HRGKLDGTPEV FA LE V Sbjct 303 VEAEAAHGTVTRHYRQHQQGKPTSTNPIASIFAWTGGLKHRGKLDGTPEVTQFAETLEDV 362 Query 366 VIATVESGKMTKDLAILIGPEQDWLNSEEFLDAIADNLEKELA 408 VI TVESGKMTKDLA LIGPEQ WL +EEFL A+ +NL LA Sbjct 363 VITTVESGKMTKDLAALIGPEQPWLTTEEFLAALDENLAARLA 405 >gi|296394293|ref|YP_003659177.1| NADP-dependent isocitrate dehydrogenase [Segniliparus rotundus DSM 44985] gi|296181440|gb|ADG98346.1| isocitrate dehydrogenase, NADP-dependent [Segniliparus rotundus DSM 44985] Length=405 Score = 672 bits (1735), Expect = 0.0, Method: Compositional matrix adjust. Identities = 316/403 (79%), Positives = 356/403 (89%), Gaps = 0/403 (0%) Query 6 KIKVSGPVVELDGDEMTRVIWKLIKDMLILPYLDIRLDYYDLGIEHRDATDDQVTIDAAY 65 KIKV G VVELDGDEMTR+IWK IKD LI PYLDI LDYYDLGIE+RDATDD+VT++AA Sbjct 3 KIKVEGVVVELDGDEMTRIIWKFIKDKLIHPYLDIELDYYDLGIENRDATDDRVTVEAAE 62 Query 66 AIKKHGVGVKCATITPDEARVEEFNLKKMWLSPNGTIRNILGGTIFREPIVISNVPRLVP 125 AIK+HGVGVKCATITPDEARV EF LKKMW SPNGTIRNILGGTIFR PI+I++VPRLVP Sbjct 63 AIKRHGVGVKCATITPDEARVVEFGLKKMWRSPNGTIRNILGGTIFRAPIIIASVPRLVP 122 Query 126 GWTKPIVIGRHAFGDQYRATNFKVDQPGTVTLTFTPADGSAPIVHEMVSIPEDGGVVLGM 185 GWTKPI+IGRHAFGDQYRAT+FK GTVT+T+TPADG PI HE+V +P++GGVV+GM Sbjct 123 GWTKPIIIGRHAFGDQYRATDFKASGAGTVTITYTPADGGEPIQHEVVKLPQEGGVVMGM 182 Query 186 YNFKESIRDFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFERVYEEEFKAQFEAA 245 YNF ESIRDFARAS +YGL +PVYLSTKNTILKAYDG FKD F+ VYE+EFKA+F+AA Sbjct 183 YNFNESIRDFARASLNYGLQQNYPVYLSTKNTILKAYDGAFKDIFQEVYEQEFKAEFDAA 242 Query 246 GLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMTADGKT 305 GLTYEHRLIDDMVA+ LKWEGGYVWACKNYDGDVQSDTVAQG+GSLGLMTSVL+T DGK Sbjct 243 GLTYEHRLIDDMVASALKWEGGYVWACKNYDGDVQSDTVAQGFGSLGLMTSVLLTPDGKI 302 Query 306 VEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAHKLESV 365 E+EAAHGTVTRHYRQYQ GKPTSTNP+ASIFAWTRG+ HRG+LDG+ V FAHKLE V Sbjct 303 CESEAAHGTVTRHYRQYQQGKPTSTNPVASIFAWTRGIAHRGRLDGSRAVEAFAHKLEDV 362 Query 366 VIATVESGKMTKDLAILIGPEQDWLNSEEFLDAIADNLEKELA 408 V+ T+E GKMTKDLA+L+G Q WL +EEFL A+ +NL+ ELA Sbjct 363 VVRTIEDGKMTKDLALLVGDGQGWLTTEEFLAALDENLQAELA 405 >gi|319948743|ref|ZP_08022863.1| isocitrate dehydrogenase [Dietzia cinnamea P4] gi|319437576|gb|EFV92576.1| isocitrate dehydrogenase [Dietzia cinnamea P4] Length=407 Score = 672 bits (1734), Expect = 0.0, Method: Compositional matrix adjust. Identities = 315/403 (79%), Positives = 361/403 (90%), Gaps = 0/403 (0%) Query 6 KIKVSGPVVELDGDEMTRVIWKLIKDMLILPYLDIRLDYYDLGIEHRDATDDQVTIDAAY 65 KIKV G VVELDGDEMTR+IWK IKD LILPYLD+ L+YYDLGIE RDATDDQ+T+DAA Sbjct 3 KIKVEGTVVELDGDEMTRIIWKFIKDELILPYLDVNLEYYDLGIESRDATDDQITVDAAN 62 Query 66 AIKKHGVGVKCATITPDEARVEEFNLKKMWLSPNGTIRNILGGTIFREPIVISNVPRLVP 125 AIK+HGVGVKCATITPDEARVEEF LK+M+ SPNGTIRNILGGTIFR PI+ISNVPRLVP Sbjct 63 AIKEHGVGVKCATITPDEARVEEFGLKRMYRSPNGTIRNILGGTIFRAPIIISNVPRLVP 122 Query 126 GWTKPIVIGRHAFGDQYRATNFKVDQPGTVTLTFTPADGSAPIVHEMVSIPEDGGVVLGM 185 GWTKPI++GRHAFGDQYRAT+FK G VT+TFTPADGS PI HE+V +PE+GGVV+GM Sbjct 123 GWTKPIIVGRHAFGDQYRATDFKAPGAGRVTITFTPADGSEPIEHEVVDLPEEGGVVMGM 182 Query 186 YNFKESIRDFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFERVYEEEFKAQFEAA 245 YNF +SI DFARASF+YGL+ +PVYLSTKNTILKAYDG FKD F+ V++ EFK +FE A Sbjct 183 YNFTKSIEDFARASFNYGLDRGYPVYLSTKNTILKAYDGAFKDIFQDVFDREFKDEFEKA 242 Query 246 GLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMTADGKT 305 GLTYEHRLIDDMVA+ LKWEGGYVWACKNYDGDVQSDTVAQG+GSLGLMTSVL+T DGKT Sbjct 243 GLTYEHRLIDDMVASSLKWEGGYVWACKNYDGDVQSDTVAQGFGSLGLMTSVLLTPDGKT 302 Query 306 VEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAHKLESV 365 EAEAAHGTVTRH+R++Q G+PTSTNPIASIFAWTRGL+HRGKLD TPEVI+FAH+LE V Sbjct 303 CEAEAAHGTVTRHFRRHQQGEPTSTNPIASIFAWTRGLEHRGKLDNTPEVIEFAHQLEDV 362 Query 366 VIATVESGKMTKDLAILIGPEQDWLNSEEFLDAIADNLEKELA 408 VI TVE G+MTKDLA+L+G +Q++LN+E+FL A+ +NL + A Sbjct 363 VINTVEGGQMTKDLALLVGDDQEYLNTEDFLAALDENLRRTRA 405 >gi|326381935|ref|ZP_08203628.1| isocitrate dehydrogenase [Gordonia neofelifaecis NRRL B-59395] gi|326199361|gb|EGD56542.1| isocitrate dehydrogenase [Gordonia neofelifaecis NRRL B-59395] Length=405 Score = 672 bits (1733), Expect = 0.0, Method: Compositional matrix adjust. Identities = 319/402 (80%), Positives = 357/402 (89%), Gaps = 0/402 (0%) Query 6 KIKVSGPVVELDGDEMTRVIWKLIKDMLILPYLDIRLDYYDLGIEHRDATDDQVTIDAAY 65 KIKV G VVELDGDEMTR+IW+ IK+ LI PYLDI L+YYDLGIEHRDATDDQVT+DAA+ Sbjct 3 KIKVEGTVVELDGDEMTRIIWQFIKEKLIHPYLDIDLEYYDLGIEHRDATDDQVTVDAAH 62 Query 66 AIKKHGVGVKCATITPDEARVEEFNLKKMWLSPNGTIRNILGGTIFREPIVISNVPRLVP 125 AI++HGVGVKCATITPDEARVEEF LKKMW SPNGTIRNILGGTIFR PI+ISNVPRLVP Sbjct 63 AIQRHGVGVKCATITPDEARVEEFGLKKMWRSPNGTIRNILGGTIFRAPILISNVPRLVP 122 Query 126 GWTKPIVIGRHAFGDQYRATNFKVDQPGTVTLTFTPADGSAPIVHEMVSIPEDGGVVLGM 185 GWTKP+V+GRHAFGDQYRAT+FKV GTVT+T+TPADGSAPI HE+V + + GGVV+GM Sbjct 123 GWTKPVVVGRHAFGDQYRATDFKVPGAGTVTITYTPADGSAPIEHEVVQMDDAGGVVMGM 182 Query 186 YNFKESIRDFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFERVYEEEFKAQFEAA 245 YNF +SI DFARASF+YGL +PVYLSTKNTILKAYDG FKD F V+E EFK +F+AA Sbjct 183 YNFNKSIEDFARASFNYGLQRNYPVYLSTKNTILKAYDGAFKDIFADVFEREFKTEFDAA 242 Query 246 GLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMTADGKT 305 GL YEHRLIDDMVA+ LKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMT DG+T Sbjct 243 GLHYEHRLIDDMVASSLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMTPDGRT 302 Query 306 VEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAHKLESV 365 EAEAAHGTVTRHYRQ+Q GKPTSTNPIASIFAWTRGL HRGKLD TPEV +FA +LE V Sbjct 303 CEAEAAHGTVTRHYRQHQQGKPTSTNPIASIFAWTRGLDHRGKLDNTPEVREFAERLEDV 362 Query 366 VIATVESGKMTKDLAILIGPEQDWLNSEEFLDAIADNLEKEL 407 VI TVE+GKMTKDLA+L+G +Q +L +EEFL A+ +NL+ L Sbjct 363 VIKTVEAGKMTKDLALLVGGDQAYLTTEEFLGALDENLQAAL 404 >gi|256380465|ref|YP_003104125.1| isocitrate dehydrogenase [Actinosynnema mirum DSM 43827] gi|255924768|gb|ACU40279.1| isocitrate dehydrogenase, NADP-dependent [Actinosynnema mirum DSM 43827] Length=406 Score = 671 bits (1732), Expect = 0.0, Method: Compositional matrix adjust. Identities = 315/403 (79%), Positives = 356/403 (89%), Gaps = 0/403 (0%) Query 6 KIKVSGPVVELDGDEMTRVIWKLIKDMLILPYLDIRLDYYDLGIEHRDATDDQVTIDAAY 65 KIKV G VVELDGDEMTR+IW+ IKD L+ PYLD+ L+YYDLGIEHRDATDDQVTIDAA Sbjct 3 KIKVQGTVVELDGDEMTRIIWQFIKDKLVHPYLDVNLEYYDLGIEHRDATDDQVTIDAAN 62 Query 66 AIKKHGVGVKCATITPDEARVEEFNLKKMWLSPNGTIRNILGGTIFREPIVISNVPRLVP 125 AIKKH VGVKCATITPDEARVEEF LKKMW+SPNGTIRNILGG +FREPI+ISN+PRLVP Sbjct 63 AIKKHNVGVKCATITPDEARVEEFGLKKMWVSPNGTIRNILGGVVFREPIIISNIPRLVP 122 Query 126 GWTKPIVIGRHAFGDQYRATNFKVDQPGTVTLTFTPADGSAPIVHEMVSIPEDGGVVLGM 185 GWTKPI+IGRHA GDQY+ATNFKV G +T+TFTP DGSAPI H + + DGGV +GM Sbjct 123 GWTKPIIIGRHAHGDQYKATNFKVPGAGKLTVTFTPEDGSAPIEHVVANYGADGGVAMGM 182 Query 186 YNFKESIRDFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFERVYEEEFKAQFEAA 245 YNF +SI DFARASFSYGL +PVY+STKNTILKAYDG FKD F++V+E EFKA+F+A Sbjct 183 YNFNKSIEDFARASFSYGLQRNYPVYMSTKNTILKAYDGAFKDIFQQVFEAEFKAEFDAK 242 Query 246 GLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMTADGKT 305 GLTYEHRLIDDMVAA +KWEGGYVWACKNYDGDVQSDTVAQG+GSLGLMTSVLMT DGKT Sbjct 243 GLTYEHRLIDDMVAAAMKWEGGYVWACKNYDGDVQSDTVAQGFGSLGLMTSVLMTPDGKT 302 Query 306 VEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAHKLESV 365 VEAEAAHGTVTRH+RQ+QAGKPTSTNPIASIFAWT GL+HRGKLDGTPEV FA LE V Sbjct 303 VEAEAAHGTVTRHFRQHQAGKPTSTNPIASIFAWTGGLKHRGKLDGTPEVTGFAETLEKV 362 Query 366 VIATVESGKMTKDLAILIGPEQDWLNSEEFLDAIADNLEKELA 408 +I TVESGKMTKDLA+L+G +Q+W +E+FL + +NL+K++A Sbjct 363 IIETVESGKMTKDLALLVGRDQEWQTTEDFLATLDENLQKKMA 405 >gi|111023201|ref|YP_706173.1| isocitrate dehydrogenase [Rhodococcus jostii RHA1] gi|110822731|gb|ABG98015.1| isocitrate dehydrogenase (NADP+) [Rhodococcus jostii RHA1] Length=407 Score = 670 bits (1729), Expect = 0.0, Method: Compositional matrix adjust. Identities = 319/403 (80%), Positives = 354/403 (88%), Gaps = 0/403 (0%) Query 6 KIKVSGPVVELDGDEMTRVIWKLIKDMLILPYLDIRLDYYDLGIEHRDATDDQVTIDAAY 65 KIKV G VVELDGDEMTR+IW+ IKD LI PYLD+ L+YYDLGIE+RD TDDQVTIDAA Sbjct 3 KIKVEGTVVELDGDEMTRIIWQFIKDKLIHPYLDVNLEYYDLGIEYRDETDDQVTIDAAN 62 Query 66 AIKKHGVGVKCATITPDEARVEEFNLKKMWLSPNGTIRNILGGTIFREPIVISNVPRLVP 125 AIKKHGVGVKCATITPDEARVEEF LKKMW SPNGTIRNILGGTIFR PI+ISNVPRLVP Sbjct 63 AIKKHGVGVKCATITPDEARVEEFGLKKMWRSPNGTIRNILGGTIFRAPIIISNVPRLVP 122 Query 126 GWTKPIVIGRHAFGDQYRATNFKVDQPGTVTLTFTPADGSAPIVHEMVSIPEDGGVVLGM 185 GWTKPI+IGRHAFGDQYRAT+FKV PG V +T+TP DGS PI HE+V+ PE GGVV G Sbjct 123 GWTKPIIIGRHAFGDQYRATDFKVPGPGKVMITYTPEDGSEPIEHELVNFPEGGGVVQGQ 182 Query 186 YNFKESIRDFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFERVYEEEFKAQFEAA 245 YNF +SI DFARAS +YGL +PVYLSTKNTILKAYDG FKD F+ VYE EFK++F+AA Sbjct 183 YNFTKSIEDFARASLNYGLQQNYPVYLSTKNTILKAYDGAFKDIFQHVYETEFKSEFDAA 242 Query 246 GLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMTADGKT 305 GLTYEHRLIDDMVA+ LKWEGGYVWACKNYDGDVQSDTVAQG+GSLGLMTSVL+T DGKT Sbjct 243 GLTYEHRLIDDMVASALKWEGGYVWACKNYDGDVQSDTVAQGFGSLGLMTSVLLTPDGKT 302 Query 306 VEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAHKLESV 365 EAEAAHGTVTRH+RQ+Q GKPTSTNPIASIFAWTRGL+HRGKLD TP+VI FA KLE V Sbjct 303 CEAEAAHGTVTRHFRQHQQGKPTSTNPIASIFAWTRGLEHRGKLDNTPDVIGFAQKLEDV 362 Query 366 VIATVESGKMTKDLAILIGPEQDWLNSEEFLDAIADNLEKELA 408 VI TVE G+MTKDLA+L+G +Q +L +EEFL A+ NL+K +A Sbjct 363 VIKTVEGGQMTKDLAMLVGGDQGYLTTEEFLGALDINLQKAIA 405 >gi|269128405|ref|YP_003301775.1| isocitrate dehydrogenase, NADP-dependent [Thermomonospora curvata DSM 43183] gi|268313363|gb|ACY99737.1| isocitrate dehydrogenase, NADP-dependent [Thermomonospora curvata DSM 43183] Length=407 Score = 670 bits (1728), Expect = 0.0, Method: Compositional matrix adjust. Identities = 317/403 (79%), Positives = 353/403 (88%), Gaps = 0/403 (0%) Query 5 PKIKVSGPVVELDGDEMTRVIWKLIKDMLILPYLDIRLDYYDLGIEHRDATDDQVTIDAA 64 PKIKV+GPVVELDGDEMTR+IWK IKD LILPYLDI L YYDLGI++RDATDDQVT+DAA Sbjct 2 PKIKVAGPVVELDGDEMTRIIWKFIKDQLILPYLDIDLKYYDLGIQNRDATDDQVTVDAA 61 Query 65 YAIKKHGVGVKCATITPDEARVEEFNLKKMWLSPNGTIRNILGGTIFREPIVISNVPRLV 124 AIKK+GVGVKCATITPDEARVEEF LK+MW SPNGTIRNILGG +FREPI++SN+PRLV Sbjct 62 NAIKKYGVGVKCATITPDEARVEEFGLKQMWRSPNGTIRNILGGVVFREPIIVSNIPRLV 121 Query 125 PGWTKPIVIGRHAFGDQYRATNFKVDQPGTVTLTFTPADGSAPIVHEMVSIPEDGGVVLG 184 PGWTKPIVIGRHA GDQY+AT+FKV PGT+T+T+TP DGS PI E+ PE GGV +G Sbjct 122 PGWTKPIVIGRHAHGDQYKATDFKVPGPGTLTITYTPDDGSEPIQFEVARYPEGGGVAMG 181 Query 185 MYNFKESIRDFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFERVYEEEFKAQFEA 244 MYNF++SI DFARASF YGL+ +PVYLSTKNTILKAYDGMFKD F +YE EFK +FEA Sbjct 182 MYNFRKSIEDFARASFRYGLDRNYPVYLSTKNTILKAYDGMFKDVFAEIYENEFKEEFEA 241 Query 245 AGLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMTADGK 304 GLTYEHRLIDDMVA LKWEGGYVWACKNYDGDVQSDTVAQG+GSLGLMTSVLMT DG+ Sbjct 242 RGLTYEHRLIDDMVACALKWEGGYVWACKNYDGDVQSDTVAQGFGSLGLMTSVLMTPDGR 301 Query 305 TVEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAHKLES 364 TVEAEAAHGTVTRHYR +Q GKPTSTNPIASIFAWTRGL HRGKLD TPEVI FA LE Sbjct 302 TVEAEAAHGTVTRHYRLHQQGKPTSTNPIASIFAWTRGLAHRGKLDNTPEVIKFAETLEQ 361 Query 365 VVIATVESGKMTKDLAILIGPEQDWLNSEEFLDAIADNLEKEL 407 V I TVESG+MTKDLA+LI +Q WL ++EFL A+ NL+K++ Sbjct 362 VCIETVESGQMTKDLALLISKDQPWLTTQEFLHALDVNLQKKI 404 >gi|72162967|ref|YP_290624.1| isocitrate dehydrogenase [Thermobifida fusca YX] gi|71916699|gb|AAZ56601.1| isocitrate dehydrogenase (NADP) [Thermobifida fusca YX] Length=406 Score = 669 bits (1725), Expect = 0.0, Method: Compositional matrix adjust. Identities = 316/403 (79%), Positives = 352/403 (88%), Gaps = 0/403 (0%) Query 6 KIKVSGPVVELDGDEMTRVIWKLIKDMLILPYLDIRLDYYDLGIEHRDATDDQVTIDAAY 65 KIKV PVVELDGDEMTR+IW IK+ LILPYLDI L YYDLGIE RD T+DQVTIDAA+ Sbjct 3 KIKVENPVVELDGDEMTRIIWSFIKERLILPYLDIDLKYYDLGIEERDRTEDQVTIDAAH 62 Query 66 AIKKHGVGVKCATITPDEARVEEFNLKKMWLSPNGTIRNILGGTIFREPIVISNVPRLVP 125 AIKK+GVGVKCATITPDEARVEEF LKKMW SPNGTIRNILGG +FREPI+ SNVPRLVP Sbjct 63 AIKKYGVGVKCATITPDEARVEEFGLKKMWRSPNGTIRNILGGVVFREPIICSNVPRLVP 122 Query 126 GWTKPIVIGRHAFGDQYRATNFKVDQPGTVTLTFTPADGSAPIVHEMVSIPEDGGVVLGM 185 GWTKPI+IGRHA GDQY+A++FKV PGTVT+T+TP +G PI E+ PE GGV LGM Sbjct 123 GWTKPIIIGRHAHGDQYKASDFKVPGPGTVTITYTPENGGEPIEMEVAKFPEGGGVALGM 182 Query 186 YNFKESIRDFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFERVYEEEFKAQFEAA 245 YNF++SI DFARA F+YGL+ +PVYLSTKNTILKAYDGMFKD F +YE EFK +FE A Sbjct 183 YNFRKSIEDFARACFNYGLDRNYPVYLSTKNTILKAYDGMFKDVFAEIYENEFKEKFEKA 242 Query 246 GLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMTADGKT 305 GLTYEHRLIDDMVAA LKWEGGYVWACKNYDGDVQSDTVAQG+GSLGLMTSVL T+DG+ Sbjct 243 GLTYEHRLIDDMVAAALKWEGGYVWACKNYDGDVQSDTVAQGFGSLGLMTSVLRTSDGRV 302 Query 306 VEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAHKLESV 365 VEAEAAHGTVTRHYRQ+Q GKPTSTNPIASIFAWTRGL+HRGKLD TP VI+FA LE V Sbjct 303 VEAEAAHGTVTRHYRQHQQGKPTSTNPIASIFAWTRGLEHRGKLDNTPAVIEFARTLEDV 362 Query 366 VIATVESGKMTKDLAILIGPEQDWLNSEEFLDAIADNLEKELA 408 VI TVESG+MTKDLAILIGP+Q+WL +E+FL + +NL+K LA Sbjct 363 VIKTVESGQMTKDLAILIGPDQEWLTTEQFLAVLDENLQKRLA 405 >gi|163839010|ref|YP_001623415.1| isocitrate dehydrogenase [Renibacterium salmoninarum ATCC 33209] gi|162952486|gb|ABY22001.1| isocitrate dehydrogenase (NADP) [Renibacterium salmoninarum ATCC 33209] Length=417 Score = 668 bits (1723), Expect = 0.0, Method: Compositional matrix adjust. Identities = 316/407 (78%), Positives = 356/407 (88%), Gaps = 0/407 (0%) Query 2 SNAPKIKVSGPVVELDGDEMTRVIWKLIKDMLILPYLDIRLDYYDLGIEHRDATDDQVTI 61 S A KIKV GPVVELDGDEMTR+IWK IKD LI PYLDI L YYDL I++RDATDDQVTI Sbjct 10 SVAYKIKVVGPVVELDGDEMTRIIWKFIKDRLIHPYLDIDLRYYDLSIQNRDATDDQVTI 69 Query 62 DAAYAIKKHGVGVKCATITPDEARVEEFNLKKMWLSPNGTIRNILGGTIFREPIVISNVP 121 DAA AIK+H VGVKCATITPDEARVEEF LKKMW+SPNGTIRNILGG +FREPI+ISN+P Sbjct 70 DAANAIKEHHVGVKCATITPDEARVEEFGLKKMWVSPNGTIRNILGGVVFREPIIISNIP 129 Query 122 RLVPGWTKPIVIGRHAFGDQYRATNFKVDQPGTVTLTFTPADGSAPIVHEMVSIPEDGGV 181 RLVPGW KPI+IGRHAFGDQYRATNFKV PG +T++F PADGS P+ ++VS PE GGV Sbjct 130 RLVPGWNKPIIIGRHAFGDQYRATNFKVPGPGKLTMSFEPADGSEPMKFDVVSYPEAGGV 189 Query 182 VLGMYNFKESIRDFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFERVYEEEFKAQ 241 +GMYNF +SI+DFARASF+YGL +PVYLSTKNTILKAYDG FKD F+ +++ EFK Q Sbjct 190 AMGMYNFTDSIKDFARASFAYGLQRNYPVYLSTKNTILKAYDGQFKDLFQEIFDNEFKDQ 249 Query 242 FEAAGLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMTA 301 F+AAGLTYEHRLIDDMVA+ +KWEGGYVWACKNYDGDVQSDTVAQG+GSLGLMTSVLMT Sbjct 250 FDAAGLTYEHRLIDDMVASAMKWEGGYVWACKNYDGDVQSDTVAQGFGSLGLMTSVLMTP 309 Query 302 DGKTVEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAHK 361 DG+TVEAEAAHGTVTRHYRQ+Q GKPTSTNPIASIFAWTRGL HRGK+D TPEVI+FA Sbjct 310 DGQTVEAEAAHGTVTRHYRQHQQGKPTSTNPIASIFAWTRGLMHRGKIDNTPEVIEFAET 369 Query 362 LESVVIATVESGKMTKDLAILIGPEQDWLNSEEFLDAIADNLEKELA 408 LE VVI TVESGKMTKDLA+L+ +Q +L +E+FL A+ +NL LA Sbjct 370 LEDVVIKTVESGKMTKDLALLVSQDQAFLTTEDFLAALDENLSARLA 416 >gi|297562889|ref|YP_003681863.1| isocitrate dehydrogenase, NADP-dependent [Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111] gi|296847337|gb|ADH69357.1| isocitrate dehydrogenase, NADP-dependent [Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111] Length=405 Score = 664 bits (1712), Expect = 0.0, Method: Compositional matrix adjust. Identities = 309/403 (77%), Positives = 356/403 (89%), Gaps = 0/403 (0%) Query 6 KIKVSGPVVELDGDEMTRVIWKLIKDMLILPYLDIRLDYYDLGIEHRDATDDQVTIDAAY 65 KIKV PVVELDGDEMTR+IW IKD LILPYLD+ L YYDLGIE RD TDDQ+T+DAA Sbjct 3 KIKVENPVVELDGDEMTRIIWSFIKDRLILPYLDVDLKYYDLGIEERDRTDDQITVDAAN 62 Query 66 AIKKHGVGVKCATITPDEARVEEFNLKKMWLSPNGTIRNILGGTIFREPIVISNVPRLVP 125 AIK+HGVGVKCATITPDEARVEEF LKKMW SPNGTIRNILGG +FREPI+ NVPRLVP Sbjct 63 AIKEHGVGVKCATITPDEARVEEFGLKKMWRSPNGTIRNILGGVVFREPIICENVPRLVP 122 Query 126 GWTKPIVIGRHAFGDQYRATNFKVDQPGTVTLTFTPADGSAPIVHEMVSIPEDGGVVLGM 185 GWTKPI+IGRHA GDQY+AT+FKV PGTVT+T+TPADGS P+ ++ + PE GGV +GM Sbjct 123 GWTKPIIIGRHAHGDQYKATDFKVPGPGTVTMTYTPADGSEPVEFDIANFPEAGGVAMGM 182 Query 186 YNFKESIRDFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFERVYEEEFKAQFEAA 245 YNF++SI DFARAS +YGL+ +PVY+STKNTILKAYDGMFKD F+ ++E EFK +F++A Sbjct 183 YNFRKSIEDFARASLNYGLDRNYPVYMSTKNTILKAYDGMFKDVFQEIFETEFKDRFDSA 242 Query 246 GLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMTADGKT 305 GLTYEHRLIDDMVAA LKWEGGYVWACKNYDGDVQSDTVAQG+GSLGLMTSVL TADG+T Sbjct 243 GLTYEHRLIDDMVAAALKWEGGYVWACKNYDGDVQSDTVAQGFGSLGLMTSVLRTADGRT 302 Query 306 VEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAHKLESV 365 VEAEAAHGTVTRHYRQ+Q GKPTSTNPIASIFAWTRGL+HRGKLD TP+V++FA+ LE V Sbjct 303 VEAEAAHGTVTRHYRQHQQGKPTSTNPIASIFAWTRGLEHRGKLDNTPKVVEFANTLEDV 362 Query 366 VIATVESGKMTKDLAILIGPEQDWLNSEEFLDAIADNLEKELA 408 VI TVE G+MTKDLA+L+G +Q++L +E+FL A+ +NL K LA Sbjct 363 VIKTVEGGQMTKDLALLVGGDQEFLTTEQFLAALDENLAKRLA 405 >gi|296268651|ref|YP_003651283.1| isocitrate dehydrogenase, NADP-dependent [Thermobispora bispora DSM 43833] gi|296091438|gb|ADG87390.1| isocitrate dehydrogenase, NADP-dependent [Thermobispora bispora DSM 43833] Length=405 Score = 664 bits (1712), Expect = 0.0, Method: Compositional matrix adjust. Identities = 314/404 (78%), Positives = 352/404 (88%), Gaps = 1/404 (0%) Query 5 PKIKVSGPVVELDGDEMTRVIWKLIKDMLILPYLDIRLDYYDLGIEHRDATDDQVTIDAA 64 PKIKV+GPVVELDGDEMTR+IW+ IK+ LILPYLDI L YYDLGI++RDATDDQVT+DAA Sbjct 2 PKIKVAGPVVELDGDEMTRIIWRFIKEQLILPYLDIDLKYYDLGIQNRDATDDQVTVDAA 61 Query 65 YAIKKHGVGVKCATITPDEARVEEFNLKKMWLSPNGTIRNILGGTIFREPIVISNVPRLV 124 YAIKK+GVGVKCATITPDEARV+EF LKKMW SPNGTIRNILGG IFREPI++ N+PRLV Sbjct 62 YAIKKYGVGVKCATITPDEARVKEFGLKKMWKSPNGTIRNILGGVIFREPIIMRNIPRLV 121 Query 125 PGWTKPIVIGRHAFGDQYRATNFKVDQPGTVTLTFTPADGSAPIVHEMVSIPEDGGVVLG 184 PGWTKP+VIGRHAFGDQYRAT+F++ GT+T+TFTP DG PI H + GV L Sbjct 122 PGWTKPVVIGRHAFGDQYRATDFRIPGEGTLTITFTPKDGGEPIEHHVYDF-NGPGVALA 180 Query 185 MYNFKESIRDFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFERVYEEEFKAQFEA 244 MYN ESIRDFARAS YGL +PVYLSTKNTILKAYDG FKD F+ VYE EFK +FEA Sbjct 181 MYNLDESIRDFARASMQYGLMRGYPVYLSTKNTILKAYDGRFKDIFQEVYENEFKEKFEA 240 Query 245 AGLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMTADGK 304 AG+TYEHRLIDDMVA+ LKWEGGYVWACKNYDGDVQSD +AQG+GSLGLMTSVLMT DGK Sbjct 241 AGITYEHRLIDDMVASSLKWEGGYVWACKNYDGDVQSDAIAQGFGSLGLMTSVLMTPDGK 300 Query 305 TVEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAHKLES 364 TVEAEAAHGTVTRHYRQYQ GKPTSTNPIASIFAWTRGLQHRGKLD PEVIDFA KLE Sbjct 301 TVEAEAAHGTVTRHYRQYQQGKPTSTNPIASIFAWTRGLQHRGKLDNQPEVIDFAQKLEQ 360 Query 365 VVIATVESGKMTKDLAILIGPEQDWLNSEEFLDAIADNLEKELA 408 V I TVE G+MTKDLA+L+G + +WL +EEFL A+A+NL+K+++ Sbjct 361 VCIETVEGGQMTKDLALLVGGDTEWLTTEEFLGALAENLKKKMS 404 >gi|302524145|ref|ZP_07276487.1| isocitrate dehydrogenase, NADP-dependent [Streptomyces sp. AA4] gi|302433040|gb|EFL04856.1| isocitrate dehydrogenase, NADP-dependent [Streptomyces sp. AA4] Length=407 Score = 664 bits (1712), Expect = 0.0, Method: Compositional matrix adjust. Identities = 310/404 (77%), Positives = 354/404 (88%), Gaps = 0/404 (0%) Query 6 KIKVSGPVVELDGDEMTRVIWKLIKDMLILPYLDIRLDYYDLGIEHRDATDDQVTIDAAY 65 KIKV G VVELDGDEMTR+IW+ IKD LI PYLD+ LDYYDLGIE RD TDDQ+TIDAA Sbjct 3 KIKVQGTVVELDGDEMTRIIWQFIKDKLIHPYLDVNLDYYDLGIEERDRTDDQITIDAAN 62 Query 66 AIKKHGVGVKCATITPDEARVEEFNLKKMWLSPNGTIRNILGGTIFREPIVISNVPRLVP 125 AIK+HGVGVKCATITPDEARVEEF LKKMW+SPNGTIRNILGG IFREPIV+ NVPRLVP Sbjct 63 AIKQHGVGVKCATITPDEARVEEFGLKKMWVSPNGTIRNILGGVIFREPIVMRNVPRLVP 122 Query 126 GWTKPIVIGRHAFGDQYRATNFKVDQPGTVTLTFTPADGSAPIVHEMVSIPEDGGVVLGM 185 GWTKPI+IGRHA GDQY+ATNFKV PGT+T+T+TP DGS P+ ++ + PE GGV +GM Sbjct 123 GWTKPIIIGRHAHGDQYKATNFKVPGPGTLTMTYTPEDGSEPMEFQVANFPEGGGVAMGM 182 Query 186 YNFKESIRDFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFERVYEEEFKAQFEAA 245 +NF++SI DFARAS YGL+ ++PVYLSTKNTILKAYDGMFKD F+ ++E EFKA F+A Sbjct 183 FNFRKSIEDFARASLQYGLDREYPVYLSTKNTILKAYDGMFKDVFQEIFETEFKADFDAK 242 Query 246 GLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMTADGKT 305 G+TYEHRLIDDMVAA LKWEGGYVWACKNYDGDVQSDTVAQG+GSLGLMTSVL T DGKT Sbjct 243 GITYEHRLIDDMVAASLKWEGGYVWACKNYDGDVQSDTVAQGFGSLGLMTSVLRTPDGKT 302 Query 306 VEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAHKLESV 365 VEAEAAHGTVTRHYRQ+Q GKPTSTNPIASI+AWTRGL+HRGKLDG E+I FA+KLE V Sbjct 303 VEAEAAHGTVTRHYRQHQQGKPTSTNPIASIYAWTRGLEHRGKLDGNSELIGFANKLEQV 362 Query 366 VIATVESGKMTKDLAILIGPEQDWLNSEEFLDAIADNLEKELAN 409 V+ TVE GKMTKDLA+L+G +Q+W +EEFL + +NL K++A Sbjct 363 VVDTVEGGKMTKDLALLVGKDQEWQTTEEFLATLDENLAKKIAQ 406 >gi|256831925|ref|YP_003160652.1| isocitrate dehydrogenase, NADP-dependent [Jonesia denitrificans DSM 20603] gi|256685456|gb|ACV08349.1| isocitrate dehydrogenase, NADP-dependent [Jonesia denitrificans DSM 20603] Length=406 Score = 663 bits (1710), Expect = 0.0, Method: Compositional matrix adjust. Identities = 310/403 (77%), Positives = 353/403 (88%), Gaps = 0/403 (0%) Query 6 KIKVSGPVVELDGDEMTRVIWKLIKDMLILPYLDIRLDYYDLGIEHRDATDDQVTIDAAY 65 KIKV PVVELDGDEMTR+IW+ IKD LI PYLDI L YYDL I++RDATDDQVT+DAA Sbjct 3 KIKVVNPVVELDGDEMTRIIWQFIKDRLIHPYLDIDLKYYDLSIQNRDATDDQVTVDAAN 62 Query 66 AIKKHGVGVKCATITPDEARVEEFNLKKMWLSPNGTIRNILGGTIFREPIVISNVPRLVP 125 AIK++ VGVKCATITPDEARVEEF LKKMW+SPNGTIRNILGG +FREPI+ISN+PRLVP Sbjct 63 AIKQYNVGVKCATITPDEARVEEFGLKKMWVSPNGTIRNILGGVVFREPIIISNIPRLVP 122 Query 126 GWTKPIVIGRHAFGDQYRATNFKVDQPGTVTLTFTPADGSAPIVHEMVSIPEDGGVVLGM 185 GW KPI+IGRHA GDQY++TNFKV G +T+TF PADGS P ++V++PE+GGV +GM Sbjct 123 GWNKPIIIGRHAHGDQYKSTNFKVPGAGKITMTFEPADGSEPQQFDVVTMPEEGGVAMGM 182 Query 186 YNFKESIRDFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFERVYEEEFKAQFEAA 245 YNF ESI+DFARASF+YGL +PVYLSTKNTILKAYDG FKD F+ V++ E+K QF+AA Sbjct 183 YNFNESIKDFARASFAYGLQRNYPVYLSTKNTILKAYDGQFKDLFQEVFDAEYKEQFDAA 242 Query 246 GLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMTADGKT 305 GLTYEHRLIDDMVA+ +KWEGGYVWACKNYDGDVQSDTVAQG+GSLGLMTSVLMT DGKT Sbjct 243 GLTYEHRLIDDMVASAMKWEGGYVWACKNYDGDVQSDTVAQGFGSLGLMTSVLMTPDGKT 302 Query 306 VEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAHKLESV 365 VEAEAAHGTVTRHYRQ+Q GKPTSTNPIASIFAWTRGL HRGKLD TPEV++FA LE V Sbjct 303 VEAEAAHGTVTRHYRQHQQGKPTSTNPIASIFAWTRGLMHRGKLDNTPEVVEFAQTLEDV 362 Query 366 VIATVESGKMTKDLAILIGPEQDWLNSEEFLDAIADNLEKELA 408 V+ TVESGKMTKDLA+LI +Q++L +EEFL AI +NL LA Sbjct 363 VVTTVESGKMTKDLALLISKDQEFLTTEEFLAAIDENLSARLA 405 >gi|226365706|ref|YP_002783489.1| isocitrate dehydrogenase [Rhodococcus opacus B4] gi|226244196|dbj|BAH54544.1| isocitrate dehydrogenase [Rhodococcus opacus B4] Length=407 Score = 662 bits (1707), Expect = 0.0, Method: Compositional matrix adjust. Identities = 314/403 (78%), Positives = 351/403 (88%), Gaps = 0/403 (0%) Query 6 KIKVSGPVVELDGDEMTRVIWKLIKDMLILPYLDIRLDYYDLGIEHRDATDDQVTIDAAY 65 KIKV G VVELDGDEMTR+IW+ IKD LI PYLD+ L+YYDLGIE+RD TDDQVT+DAA Sbjct 3 KIKVEGTVVELDGDEMTRIIWQFIKDKLIHPYLDVNLEYYDLGIEYRDETDDQVTVDAAN 62 Query 66 AIKKHGVGVKCATITPDEARVEEFNLKKMWLSPNGTIRNILGGTIFREPIVISNVPRLVP 125 AIKKHGVGVKCATITPDEARVEEF LKKMW SPNGTIRNILGGTIFR PI+ISNVPRLVP Sbjct 63 AIKKHGVGVKCATITPDEARVEEFGLKKMWRSPNGTIRNILGGTIFRAPIIISNVPRLVP 122 Query 126 GWTKPIVIGRHAFGDQYRATNFKVDQPGTVTLTFTPADGSAPIVHEMVSIPEDGGVVLGM 185 GWTKPI+IGRHAFGDQYRAT+FKV PG V +T+TP DGS PI HE+V+ P+ GGVV G Sbjct 123 GWTKPIIIGRHAFGDQYRATDFKVPGPGKVMITYTPEDGSEPIEHELVNFPDGGGVVQGQ 182 Query 186 YNFKESIRDFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFERVYEEEFKAQFEAA 245 YNF +SI DFARAS +YGL +PVYLSTKNTILKAYDG FKD F+ VYE EFK +F+AA Sbjct 183 YNFTKSIEDFARASLNYGLQQNYPVYLSTKNTILKAYDGAFKDIFQHVYETEFKPEFDAA 242 Query 246 GLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMTADGKT 305 GLTYEHRLIDDMVA+ LKWEGGYVWACKNYDGDVQSDTVAQG+GSLGLMTSVL+T DG T Sbjct 243 GLTYEHRLIDDMVASALKWEGGYVWACKNYDGDVQSDTVAQGFGSLGLMTSVLLTPDGNT 302 Query 306 VEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAHKLESV 365 EAEAAHGTVTRH+RQ+Q GKPTSTNPIASIFAWTRGL+HRGKLD TP+VI FA +LE V Sbjct 303 CEAEAAHGTVTRHFRQHQQGKPTSTNPIASIFAWTRGLEHRGKLDNTPDVIGFAQELEDV 362 Query 366 VIATVESGKMTKDLAILIGPEQDWLNSEEFLDAIADNLEKELA 408 VI TVE G+MTKDLA+L+G +Q +L +EEFL + NL+K +A Sbjct 363 VIKTVEGGQMTKDLAMLVGGDQGYLTTEEFLGTLDINLQKAIA 405 >gi|297625896|ref|YP_003687659.1| isocitrate/isopropylmalate dehydrogenase [Propionibacterium freudenreichii subsp. shermanii CIRM-BIA1] gi|296921661|emb|CBL56218.1| Putative isocitrate/isopropylmalate dehydrogenase [Propionibacterium freudenreichii subsp. shermanii CIRM-BIA1] Length=405 Score = 660 bits (1703), Expect = 0.0, Method: Compositional matrix adjust. Identities = 312/402 (78%), Positives = 356/402 (89%), Gaps = 0/402 (0%) Query 6 KIKVSGPVVELDGDEMTRVIWKLIKDMLILPYLDIRLDYYDLGIEHRDATDDQVTIDAAY 65 KIKV G VVELDGDEMTR+IWKLIKD LILPYLDI LDYYDLGIEHRDATDDQVT+DAA Sbjct 3 KIKVEGTVVELDGDEMTRIIWKLIKDELILPYLDINLDYYDLGIEHRDATDDQVTVDAAN 62 Query 66 AIKKHGVGVKCATITPDEARVEEFNLKKMWLSPNGTIRNILGGTIFREPIVISNVPRLVP 125 AIKKHGVGVKCATITPDEARV+EF LKKMW SPNGTIRNILGG IFREPIVISN+PRLVP Sbjct 63 AIKKHGVGVKCATITPDEARVKEFGLKKMWRSPNGTIRNILGGVIFREPIVISNIPRLVP 122 Query 126 GWTKPIVIGRHAFGDQYRATNFKVDQPGTVTLTFTPADGSAPIVHEMVSIPEDGGVVLGM 185 GW KPIVIGRHAFGDQYRAT+ K+ GTVTLT+TP DGS P+ E+V +PE GGV +GM Sbjct 123 GWKKPIVIGRHAFGDQYRATDVKLPGAGTVTLTYTPDDGSEPMEMEVVKMPEAGGVAMGM 182 Query 186 YNFKESIRDFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFERVYEEEFKAQFEAA 245 YNF +SI DFARASF+YGLN +PVYLSTKNTILKAYDG FKD F R++E+E+K +F+AA Sbjct 183 YNFNKSIEDFARASFNYGLNRHYPVYLSTKNTILKAYDGQFKDIFARIFEDEYKERFDAA 242 Query 246 GLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMTADGKT 305 GLTYEHRLIDDMVA+ LKWEGGYVWACKNYDGDVQSD VAQG+GSLGLMTSVL++ DGKT Sbjct 243 GLTYEHRLIDDMVASALKWEGGYVWACKNYDGDVQSDIVAQGFGSLGLMTSVLLSPDGKT 302 Query 306 VEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAHKLESV 365 +EAEAAHGTVTRHYR+YQAG+ TSTNPIAS+FAWT GL+HRG+LDGTP ++ FA LE+V Sbjct 303 MEAEAAHGTVTRHYRKYQAGEETSTNPIASVFAWTGGLRHRGELDGTPGLVAFADTLENV 362 Query 366 VIATVESGKMTKDLAILIGPEQDWLNSEEFLDAIADNLEKEL 407 + TVESG+MTKDLA L+G +Q +LN+E+F+ A++D L + L Sbjct 363 CVKTVESGRMTKDLASLVGGDQGYLNTEDFMKALSDGLAEAL 404 >gi|229821488|ref|YP_002883014.1| isocitrate dehydrogenase [Beutenbergia cavernae DSM 12333] gi|229567401|gb|ACQ81252.1| isocitrate dehydrogenase, NADP-dependent [Beutenbergia cavernae DSM 12333] Length=405 Score = 657 bits (1694), Expect = 0.0, Method: Compositional matrix adjust. Identities = 312/403 (78%), Positives = 348/403 (87%), Gaps = 0/403 (0%) Query 6 KIKVSGPVVELDGDEMTRVIWKLIKDMLILPYLDIRLDYYDLGIEHRDATDDQVTIDAAY 65 KIKV+GPVVELDGDEMTR+IW+ IKD LI PYLD+ L YYDL IE RDATDDQ+TIDAA Sbjct 3 KIKVAGPVVELDGDEMTRIIWQFIKDRLIHPYLDVDLRYYDLSIESRDATDDQITIDAAN 62 Query 66 AIKKHGVGVKCATITPDEARVEEFNLKKMWLSPNGTIRNILGGTIFREPIVISNVPRLVP 125 AIK+H VGVKCATITPDEARVEEF LKKMW SPNGTIRNILGG +FREPI+ISNVPRLVP Sbjct 63 AIKEHHVGVKCATITPDEARVEEFGLKKMWRSPNGTIRNILGGVVFREPIIISNVPRLVP 122 Query 126 GWTKPIVIGRHAFGDQYRATNFKVDQPGTVTLTFTPADGSAPIVHEMVSIPEDGGVVLGM 185 GWTKPI+IGRHA GDQY+AT+F+V G +T+TFTPADGS PI H + DGGV +GM Sbjct 123 GWTKPIIIGRHAHGDQYKATDFRVPGAGELTVTFTPADGSEPIQHVIAEYGADGGVAMGM 182 Query 186 YNFKESIRDFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFERVYEEEFKAQFEAA 245 YN+ +SIRDFARASFSYGL +PVYLSTKNTILKAYDG FKD F V+E EFKA F+AA Sbjct 183 YNYDDSIRDFARASFSYGLQRSYPVYLSTKNTILKAYDGRFKDLFADVFETEFKADFDAA 242 Query 246 GLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMTADGKT 305 GLTYEHRLIDDMVA+ +KWEGGYVWACKNYDGDVQSDTVAQG+GSLGLMTSVLMT DG+T Sbjct 243 GLTYEHRLIDDMVASAMKWEGGYVWACKNYDGDVQSDTVAQGFGSLGLMTSVLMTPDGQT 302 Query 306 VEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAHKLESV 365 VEAEAAHGTVTRHYRQ+QAGKPTSTNPIASIFAWT GL+HRGKLDGTPEV FA LE V Sbjct 303 VEAEAAHGTVTRHYRQHQAGKPTSTNPIASIFAWTGGLKHRGKLDGTPEVTGFAEALEDV 362 Query 366 VIATVESGKMTKDLAILIGPEQDWLNSEEFLDAIADNLEKELA 408 V+ +VE+G MTKDLA+L+GP+Q W +EEFL + +NL LA Sbjct 363 VVKSVEAGAMTKDLALLVGPDQAWQTTEEFLATLDENLAARLA 405 >gi|257054575|ref|YP_003132407.1| isocitrate dehydrogenase [Saccharomonospora viridis DSM 43017] gi|256584447|gb|ACU95580.1| isocitrate dehydrogenase (NADP) [Saccharomonospora viridis DSM 43017] Length=407 Score = 656 bits (1693), Expect = 0.0, Method: Compositional matrix adjust. Identities = 310/404 (77%), Positives = 350/404 (87%), Gaps = 0/404 (0%) Query 6 KIKVSGPVVELDGDEMTRVIWKLIKDMLILPYLDIRLDYYDLGIEHRDATDDQVTIDAAY 65 KIKV G VVELDGDEMTR+IWK IKD LI PYLDI L+YYDLGIE RD TDDQ+T+DAA+ Sbjct 3 KIKVEGTVVELDGDEMTRIIWKFIKDKLIHPYLDINLEYYDLGIEERDRTDDQITVDAAH 62 Query 66 AIKKHGVGVKCATITPDEARVEEFNLKKMWLSPNGTIRNILGGTIFREPIVISNVPRLVP 125 AI KHGVGVKCATITPDEARVEEF LKKMW SPNGTIRNILGG +FREPI+ISN+PRLVP Sbjct 63 AIAKHGVGVKCATITPDEARVEEFGLKKMWRSPNGTIRNILGGVVFREPIIISNIPRLVP 122 Query 126 GWTKPIVIGRHAFGDQYRATNFKVDQPGTVTLTFTPADGSAPIVHEMVSIPEDGGVVLGM 185 GWTKPI+IGRHA GDQY+A++FKV PGTVT+T+TP DGS PI E+ PE GGV +GM Sbjct 123 GWTKPIIIGRHAHGDQYKASDFKVPGPGTVTITYTPDDGSEPIEMEVAKFPEGGGVAMGM 182 Query 186 YNFKESIRDFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFERVYEEEFKAQFEAA 245 YNF++SI DFARASF+YGL+ +PVY+STKNTILKAYDGMFKD F+ +Y+ EFK +FEA Sbjct 183 YNFRKSIEDFARASFNYGLDRGYPVYMSTKNTILKAYDGMFKDVFQEIYDNEFKDKFEAR 242 Query 246 GLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMTADGKT 305 GLTYEHRLIDDMVAA LKWEGGYVWACKNYDGDVQSDTVAQG+GSLGLMTSVL T DG+T Sbjct 243 GLTYEHRLIDDMVAASLKWEGGYVWACKNYDGDVQSDTVAQGFGSLGLMTSVLRTPDGRT 302 Query 306 VEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAHKLESV 365 VEAEAAHGTVTRHYRQ+Q GKPTSTNPIASIFAWTRGL+HRGKLD E+I FA+ LE V Sbjct 303 VEAEAAHGTVTRHYRQHQQGKPTSTNPIASIFAWTRGLEHRGKLDNNSELIGFANTLEKV 362 Query 366 VIATVESGKMTKDLAILIGPEQDWLNSEEFLDAIADNLEKELAN 409 VI TVESGKMTKDLA+L+G + +L +EEFL + NL ++A Sbjct 363 VIETVESGKMTKDLALLVGGDTPYLTTEEFLATLDANLAAKIAQ 406 >gi|117927597|ref|YP_872148.1| isocitrate dehydrogenase [Acidothermus cellulolyticus 11B] gi|117648060|gb|ABK52162.1| isocitrate dehydrogenase (NADP) [Acidothermus cellulolyticus 11B] Length=407 Score = 654 bits (1687), Expect = 0.0, Method: Compositional matrix adjust. Identities = 311/404 (77%), Positives = 349/404 (87%), Gaps = 1/404 (0%) Query 5 PKIKVSGPVVELDGDEMTRVIWKLIKDMLILPYLDIRLDYYDLGIEHRDATDDQVTIDAA 64 PKIKV+ P+VELDGDEMTRVIW++IK+ L+ PYLDI L Y+DLGIE+RDATDDQVTIDAA Sbjct 2 PKIKVANPIVELDGDEMTRVIWRMIKEQLLFPYLDIPLLYFDLGIENRDATDDQVTIDAA 61 Query 65 YAIKKHGVGVKCATITPDEARVEEFNLKKMWLSPNGTIRNILGGTIFREPIVISNVPRLV 124 YAIK+HGVGVKCATITPDEARV EF LKKMW SPNGTIRNILGG IFREPI+ISN+PRLV Sbjct 62 YAIKEHGVGVKCATITPDEARVAEFGLKKMWKSPNGTIRNILGGVIFREPIIISNIPRLV 121 Query 125 PGWTKPIVIGRHAFGDQYRATNFKVDQPGTVTLTFTPADGSAPIVHEMVSIPEDGGVVLG 184 P WTKPIVIGRHA GDQYRAT+F V PG VTLT+TPADG AP+ E+ GGV LG Sbjct 122 PSWTKPIVIGRHAHGDQYRATDFVVPGPGRVTLTYTPADGGAPVEFEVAEF-SGGGVALG 180 Query 185 MYNFKESIRDFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFERVYEEEFKAQFEA 244 MYN+ ESIRDFARA F YGL+ +PVYLSTKNTILKAYDG FKD F V+ +EF+ F+ Sbjct 181 MYNYDESIRDFARACFRYGLDRGYPVYLSTKNTILKAYDGRFKDIFAEVFAQEFETAFKE 240 Query 245 AGLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMTADGK 304 AGL+YEHRLIDDMVA+ LKWEGGYVWACKNYDGDVQSD VAQG+GSLGLMTSVLMT DG+ Sbjct 241 AGLSYEHRLIDDMVASALKWEGGYVWACKNYDGDVQSDAVAQGFGSLGLMTSVLMTPDGR 300 Query 305 TVEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAHKLES 364 TVEAEAAHGTVTRH+R +Q GKPTSTNPIASI+AWTRGL+HRGKLDGTPEV+ FA LE Sbjct 301 TVEAEAAHGTVTRHFRLHQQGKPTSTNPIASIYAWTRGLEHRGKLDGTPEVVRFARTLEE 360 Query 365 VVIATVESGKMTKDLAILIGPEQDWLNSEEFLDAIADNLEKELA 408 V + TVESGKMTKDLA+L+GPE WL +EEFL A+A+NL+ LA Sbjct 361 VCVRTVESGKMTKDLAMLVGPETPWLTTEEFLAALAENLQAALA 404 >gi|134103066|ref|YP_001108727.1| isocitrate dehydrogenase [Saccharopolyspora erythraea NRRL 2338] gi|133915689|emb|CAM05802.1| isocitrate dehydrogenase, NADP-dependent [Saccharopolyspora erythraea NRRL 2338] Length=406 Score = 652 bits (1683), Expect = 0.0, Method: Compositional matrix adjust. Identities = 309/404 (77%), Positives = 347/404 (86%), Gaps = 1/404 (0%) Query 6 KIKVSGPVVELDGDEMTRVIWKLIKDMLILPYLDIRLDYYDLGIEHRDATDDQVTIDAAY 65 KIKV G + ELDGDEMTR+IW+ IKD LI PYLD+ LDYYDLGIEHRDATDDQVT+DAA Sbjct 3 KIKVQGTIAELDGDEMTRIIWQFIKDKLIHPYLDVNLDYYDLGIEHRDATDDQVTVDAAN 62 Query 66 AIKKHGVGVKCATITPDEARVEEFNLKKMWLSPNGTIRNILGGTIFREPIVISNVPRLVP 125 AIKK+GVGVKCATITPDEARVEEF LKKMW SPNGTIRNILGG IFREPIVISN+PR VP Sbjct 63 AIKKYGVGVKCATITPDEARVEEFGLKKMWRSPNGTIRNILGGVIFREPIVISNIPRYVP 122 Query 126 GWTKPIVIGRHAFGDQYRATNFKVDQPGTVTLTFTPADGSAPIVHEMVSIPEDGGVVLGM 185 WTKPIVIGRHA GDQY+AT+FKV PGTVT+T+TP DG PI E+ EDGGV + M Sbjct 123 TWTKPIVIGRHAHGDQYKATDFKVPGPGTVTVTYTPEDGGEPIEFEVAKFGEDGGVAMAM 182 Query 186 YNFKESIRDFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFERVYEEEFKAQFEAA 245 YN++ SI +FARASF YGL +PVY+STKNTILKAYDG+FKD F+ V++ E+KA F+A Sbjct 183 YNYRRSIEEFARASFRYGLERGYPVYMSTKNTILKAYDGLFKDVFQEVFDNEYKADFDAK 242 Query 246 GLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMTADGKT 305 GLTYEHRLIDDMVA +KWEGGYVWACKNYDGDVQSDTVAQG+GSLGLMTSVLMT DGK Sbjct 243 GLTYEHRLIDDMVATAMKWEGGYVWACKNYDGDVQSDTVAQGFGSLGLMTSVLMTEDGK- 301 Query 306 VEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAHKLESV 365 VEAEAAHGTVTRH+RQ+Q GKPTSTNPIASIFAWTRGLQHRGKLD TPEV+ FA LE V Sbjct 302 VEAEAAHGTVTRHFRQHQQGKPTSTNPIASIFAWTRGLQHRGKLDSTPEVVGFAETLEKV 361 Query 366 VIATVESGKMTKDLAILIGPEQDWLNSEEFLDAIADNLEKELAN 409 VI TVESG+MTKDLA+L+G +Q + +EEFL + DNL+K +AN Sbjct 362 VIETVESGRMTKDLALLVGGDQGYQTTEEFLATLDDNLQKRMAN 405 >gi|300782764|ref|YP_003763055.1| isocitrate dehydrogenase [Amycolatopsis mediterranei U32] gi|299792278|gb|ADJ42653.1| isocitrate dehydrogenase [Amycolatopsis mediterranei U32] gi|340524138|gb|AEK39343.1| isocitrate dehydrogenase [Amycolatopsis mediterranei S699] Length=407 Score = 652 bits (1681), Expect = 0.0, Method: Compositional matrix adjust. Identities = 306/404 (76%), Positives = 346/404 (86%), Gaps = 0/404 (0%) Query 6 KIKVSGPVVELDGDEMTRVIWKLIKDMLILPYLDIRLDYYDLGIEHRDATDDQVTIDAAY 65 KIKV G VVELDGDEMTR+IW+ IKD LI PYLD+ LDYYDLGIE RD TDDQVT+D+A Sbjct 3 KIKVQGTVVELDGDEMTRIIWQFIKDKLIHPYLDVNLDYYDLGIEERDRTDDQVTVDSAN 62 Query 66 AIKKHGVGVKCATITPDEARVEEFNLKKMWLSPNGTIRNILGGTIFREPIVISNVPRLVP 125 AIKKHGVGVKCATITPDEARVEEF LKKMWLSPNGTIRNILGG IFREPIVI N+PRLVP Sbjct 63 AIKKHGVGVKCATITPDEARVEEFGLKKMWLSPNGTIRNILGGVIFREPIVIQNIPRLVP 122 Query 126 GWTKPIVIGRHAFGDQYRATNFKVDQPGTVTLTFTPADGSAPIVHEMVSIPEDGGVVLGM 185 WTKPI+IGRHA GDQY+ATNFKV PG +T+++TP DGS P+ ++ PE GGV +GM Sbjct 123 TWTKPIIIGRHAHGDQYKATNFKVPGPGKLTISYTPDDGSEPMEFQVAQFPEGGGVAMGM 182 Query 186 YNFKESIRDFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFERVYEEEFKAQFEAA 245 YNFK+SI DFARAS YGL+ PVYLSTKNTILKAYDG FKD FE +++ EFKA F+A Sbjct 183 YNFKKSIEDFARASLQYGLDRGLPVYLSTKNTILKAYDGQFKDVFEEIFQNEFKADFDAK 242 Query 246 GLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMTADGKT 305 G++YEHRLIDDMVAA +KWEGGYVWACKNYDGDVQSDTVAQG+GSLGLMTSVL T DG+T Sbjct 243 GISYEHRLIDDMVAAAMKWEGGYVWACKNYDGDVQSDTVAQGFGSLGLMTSVLRTPDGRT 302 Query 306 VEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAHKLESV 365 VEAEAAHGTVTRHYRQ+Q GKPTSTNPIASI+AWTRGL+HRGKLDG E+I FA+ LE V Sbjct 303 VEAEAAHGTVTRHYRQHQQGKPTSTNPIASIYAWTRGLEHRGKLDGNQELIGFANTLEQV 362 Query 366 VIATVESGKMTKDLAILIGPEQDWLNSEEFLDAIADNLEKELAN 409 V+ TVESG+MTKDLA+LI +Q W +EEFL + DNL K++A Sbjct 363 VVETVESGQMTKDLALLISKDQPWQTTEEFLATLDDNLAKKIAQ 406 >gi|271962799|ref|YP_003336995.1| isocitrate dehydrogenase (NADP(+)) [Streptosporangium roseum DSM 43021] gi|270505974|gb|ACZ84252.1| Isocitrate dehydrogenase (NADP(+)) [Streptosporangium roseum DSM 43021] Length=404 Score = 650 bits (1677), Expect = 0.0, Method: Compositional matrix adjust. Identities = 309/404 (77%), Positives = 349/404 (87%), Gaps = 1/404 (0%) Query 5 PKIKVSGPVVELDGDEMTRVIWKLIKDMLILPYLDIRLDYYDLGIEHRDATDDQVTIDAA 64 PKIKV GPVVELDGDEMTR+IW+ IKD LILPYLD+ L YYDLGIEHRDATDDQVTIDAA Sbjct 2 PKIKVEGPVVELDGDEMTRIIWQFIKDQLILPYLDVDLKYYDLGIEHRDATDDQVTIDAA 61 Query 65 YAIKKHGVGVKCATITPDEARVEEFNLKKMWLSPNGTIRNILGGTIFREPIVISNVPRLV 124 AIK++GVGVKCATITPDEARVEEF LKKMW SPNGTIRNILGG IFREPI++SNVPRLV Sbjct 62 NAIKQYGVGVKCATITPDEARVEEFGLKKMWKSPNGTIRNILGGVIFREPIIMSNVPRLV 121 Query 125 PGWTKPIVIGRHAFGDQYRATNFKVDQPGTVTLTFTPADGSAPIVHEMVSIPEDGGVVLG 184 PGWTKPI+IGRHAFGDQYRAT+ K+ GT+TLT+TP DGS PI ++ P G+ + Sbjct 122 PGWTKPIIIGRHAFGDQYRATDLKIPGEGTLTLTYTPKDGSEPIELDVYDFP-GSGIAMA 180 Query 185 MYNFKESIRDFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFERVYEEEFKAQFEA 244 MYN +SIRDFARAS YGL+ +PVYLSTKNTILKAYDG FKD F V+E EFKA+FEA Sbjct 181 MYNLDDSIRDFARASMRYGLSRGYPVYLSTKNTILKAYDGRFKDIFAEVFETEFKAEFEA 240 Query 245 AGLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMTADGK 304 AG+TYEHRLIDDMVAA LKWEGGYVWA KNYDGDVQSDTVAQG+GSLGLMTSVL+T DG+ Sbjct 241 AGITYEHRLIDDMVAAALKWEGGYVWAAKNYDGDVQSDTVAQGFGSLGLMTSVLLTPDGR 300 Query 305 TVEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAHKLES 364 TVEAEAAHGTVTRHYR++Q G PTSTNPIASIFAWTRGL HRGKLD TP VIDFA KLE Sbjct 301 TVEAEAAHGTVTRHYREHQKGNPTSTNPIASIFAWTRGLAHRGKLDNTPAVIDFAEKLEQ 360 Query 365 VVIATVESGKMTKDLAILIGPEQDWLNSEEFLDAIADNLEKELA 408 V + TVE G+MTKDLA+L+G + WL +++FL A+ +NL+K++A Sbjct 361 VCVETVEGGQMTKDLALLVGGDAKWLTTQDFLAALDENLKKKMA 404 >gi|238060986|ref|ZP_04605695.1| isocitrate dehydrogenase [Micromonospora sp. ATCC 39149] gi|237882797|gb|EEP71625.1| isocitrate dehydrogenase [Micromonospora sp. ATCC 39149] Length=405 Score = 649 bits (1675), Expect = 0.0, Method: Compositional matrix adjust. Identities = 307/403 (77%), Positives = 353/403 (88%), Gaps = 1/403 (0%) Query 6 KIKVSGPVVELDGDEMTRVIWKLIKDMLILPYLDIRLDYYDLGIEHRDATDDQVTIDAAY 65 KIKV+ PVVELDGDEMTR+IWK I++ LILPYLD+ L YYDL I++RD+TDDQVTIDAA Sbjct 3 KIKVNNPVVELDGDEMTRIIWKQIREQLILPYLDVDLHYYDLSIQYRDSTDDQVTIDAAN 62 Query 66 AIKKHGVGVKCATITPDEARVEEFNLKKMWLSPNGTIRNILGGTIFREPIVISNVPRLVP 125 AIK+HGVGVKCATITPDEARVEEF LKKMW SPNGTIRNILGG +FREPI++SNVPRLVP Sbjct 63 AIKEHGVGVKCATITPDEARVEEFGLKKMWRSPNGTIRNILGGVVFREPIIMSNVPRLVP 122 Query 126 GWTKPIVIGRHAFGDQYRATNFKVDQPGTVTLTFTPADGSAPIVHEMVSIPEDGGVVLGM 185 GWTKPI+IGRHA GDQY+AT+F V PGTVT+T+TPADGSAP+ E+ + P GGV +GM Sbjct 123 GWTKPIIIGRHAHGDQYKATDFVVPGPGTVTITYTPADGSAPVEMEIANFP-GGGVTMGM 181 Query 186 YNFKESIRDFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFERVYEEEFKAQFEAA 245 YNF +SIRDFARAS YGL+ +PVYLSTKNTILKAYDG FKD F V+E EFKA+FEAA Sbjct 182 YNFDDSIRDFARASMRYGLDRGYPVYLSTKNTILKAYDGRFKDIFAEVFENEFKAEFEAA 241 Query 246 GLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMTADGKT 305 G++YEHRLIDDMVAA LKWEGG+VWACKNYDGDVQSDTVAQG+GSLGLMTSVLMT DG+T Sbjct 242 GISYEHRLIDDMVAAALKWEGGFVWACKNYDGDVQSDTVAQGFGSLGLMTSVLMTPDGRT 301 Query 306 VEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAHKLESV 365 VEAEAAHGTVTRHYRQYQ G+ TSTNPIASI+AWTRGL HRGKLDGTP V +FA+ LE V Sbjct 302 VEAEAAHGTVTRHYRQYQKGEKTSTNPIASIYAWTRGLAHRGKLDGTPAVTEFANTLEQV 361 Query 366 VIATVESGKMTKDLAILIGPEQDWLNSEEFLDAIADNLEKELA 408 +I TVE G+MTKDLA+LI + WL ++EF++A+ +NL + LA Sbjct 362 IIDTVEGGQMTKDLALLISRDAPWLTTDEFMNALDENLARRLA 404 >gi|152967931|ref|YP_001363715.1| isocitrate dehydrogenase [Kineococcus radiotolerans SRS30216] gi|151362448|gb|ABS05451.1| isocitrate dehydrogenase, NADP-dependent [Kineococcus radiotolerans SRS30216] Length=404 Score = 649 bits (1673), Expect = 0.0, Method: Compositional matrix adjust. Identities = 309/403 (77%), Positives = 342/403 (85%), Gaps = 1/403 (0%) Query 6 KIKVSGPVVELDGDEMTRVIWKLIKDMLILPYLDIRLDYYDLGIEHRDATDDQVTIDAAY 65 KIKV GPVVELDGDEMTR+IW+ IKD L+ PYLD+ L+YYDLG+EHRDATDDQVTIDAA+ Sbjct 3 KIKVQGPVVELDGDEMTRIIWQFIKDRLVHPYLDVDLEYYDLGVEHRDATDDQVTIDAAH 62 Query 66 AIKKHGVGVKCATITPDEARVEEFNLKKMWLSPNGTIRNILGGTIFREPIVISNVPRLVP 125 AI++ GVGVKCATITPDEARVEEF LKKMW SPNGTIRNILGG IFREPI+ISN+PRLVP Sbjct 63 AIQRAGVGVKCATITPDEARVEEFGLKKMWRSPNGTIRNILGGVIFREPIIISNIPRLVP 122 Query 126 GWTKPIVIGRHAFGDQYRATNFKVDQPGTVTLTFTPADGSAPIVHEMVSIPEDGGVVLGM 185 GWTKPI++GRHA+GDQYRAT+FK GT+T+TFTP DGS PI HE+ P GV L M Sbjct 123 GWTKPIIVGRHAYGDQYRATDFKFPSAGTLTVTFTPEDGSEPIEHEVFQAP-GAGVSLSM 181 Query 186 YNFKESIRDFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFERVYEEEFKAQFEAA 245 YN SI DFAR+S +YGL +PVYLSTKNTILKAYDG FKD FE V+E EFK +F A Sbjct 182 YNLDASIVDFARSSLNYGLARNYPVYLSTKNTILKAYDGRFKDIFEEVFENEFKDRFAEA 241 Query 246 GLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMTADGKT 305 G+TYEHRLIDDMVAA LKWEGGYVWACKNYDGDVQSDTVAQG+GSLGLMTSVL T DG Sbjct 242 GITYEHRLIDDMVAASLKWEGGYVWACKNYDGDVQSDTVAQGFGSLGLMTSVLSTPDGSV 301 Query 306 VEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAHKLESV 365 VEAEAAHGTVTRHYRQ+Q GKPTSTNPIASI+AWTRGL HRGKLD TPEV FA LE V Sbjct 302 VEAEAAHGTVTRHYRQHQQGKPTSTNPIASIYAWTRGLAHRGKLDSTPEVTGFAETLEDV 361 Query 366 VIATVESGKMTKDLAILIGPEQDWLNSEEFLDAIADNLEKELA 408 VI TVESGKMTKDLA+L+GP+Q W +EEFL ++ DNL LA Sbjct 362 VIKTVESGKMTKDLALLVGPDQPWQTTEEFLGSLDDNLAARLA 404 >gi|331699060|ref|YP_004335299.1| isocitrate dehydrogenase, NADP-dependent [Pseudonocardia dioxanivorans CB1190] gi|326953749|gb|AEA27446.1| isocitrate dehydrogenase, NADP-dependent [Pseudonocardia dioxanivorans CB1190] Length=404 Score = 648 bits (1672), Expect = 0.0, Method: Compositional matrix adjust. Identities = 312/403 (78%), Positives = 342/403 (85%), Gaps = 1/403 (0%) Query 6 KIKVSGPVVELDGDEMTRVIWKLIKDMLILPYLDIRLDYYDLGIEHRDATDDQVTIDAAY 65 KIKV G VVELDGDEMTR+IW+ IKD LI PYLD+ L+YYDLGIE RD TDDQ+T+DAA Sbjct 3 KIKVEGTVVELDGDEMTRIIWQFIKDKLIHPYLDVNLEYYDLGIETRDKTDDQITVDAAN 62 Query 66 AIKKHGVGVKCATITPDEARVEEFNLKKMWLSPNGTIRNILGGTIFREPIVISNVPRLVP 125 AIKKHGVGVKCATITPDEARVEEF LKKMW SPNGTIRNILGG IFREPI+ISN+PRLVP Sbjct 63 AIKKHGVGVKCATITPDEARVEEFGLKKMWRSPNGTIRNILGGVIFREPIIISNIPRLVP 122 Query 126 GWTKPIVIGRHAFGDQYRATNFKVDQPGTVTLTFTPADGSAPIVHEMVSIPEDGGVVLGM 185 GWTKPI++GRHAFGDQYRAT+FK GT+T+TFTPADGS PI HE+ P GV + M Sbjct 123 GWTKPIIVGRHAFGDQYRATDFKFPGEGTLTVTFTPADGSEPIQHEVFQAP-GSGVAMAM 181 Query 186 YNFKESIRDFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFERVYEEEFKAQFEAA 245 YN ESIRDFARAS +YGL +PVYLSTKNTILKAYDG FKD F VYE EFK QFEA Sbjct 182 YNLDESIRDFARASMNYGLTRDYPVYLSTKNTILKAYDGRFKDLFAEVYETEFKEQFEAK 241 Query 246 GLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMTADGKT 305 GLTYEHRLIDDMVAA LKWEGGYVWA KNYDGDVQSDTVAQG+GSLGLMTSVLMT DGKT Sbjct 242 GLTYEHRLIDDMVAAALKWEGGYVWAAKNYDGDVQSDTVAQGFGSLGLMTSVLMTPDGKT 301 Query 306 VEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAHKLESV 365 VEAEAAHGTVTRHYRQ+QAGKPTSTNPIASI+AWTRGL HRGKLD PE+I F+ LE V Sbjct 302 VEAEAAHGTVTRHYRQHQAGKPTSTNPIASIYAWTRGLAHRGKLDNNPELIAFSEALEDV 361 Query 366 VIATVESGKMTKDLAILIGPEQDWLNSEEFLDAIADNLEKELA 408 V+ TVESGKMTKDLA+LI + + +EEFL+ + NL+K A Sbjct 362 VVKTVESGKMTKDLALLIDKDAPFQTTEEFLETLDANLQKARA 404 >gi|302869826|ref|YP_003838463.1| isocitrate dehydrogenase, NADP-dependent [Micromonospora aurantiaca ATCC 27029] gi|315501289|ref|YP_004080176.1| isocitrate dehydrogenase, nADP-dependent [Micromonospora sp. L5] gi|302572685|gb|ADL48887.1| isocitrate dehydrogenase, NADP-dependent [Micromonospora aurantiaca ATCC 27029] gi|315407908|gb|ADU06025.1| isocitrate dehydrogenase, NADP-dependent [Micromonospora sp. L5] Length=405 Score = 647 bits (1670), Expect = 0.0, Method: Compositional matrix adjust. Identities = 304/403 (76%), Positives = 352/403 (88%), Gaps = 1/403 (0%) Query 6 KIKVSGPVVELDGDEMTRVIWKLIKDMLILPYLDIRLDYYDLGIEHRDATDDQVTIDAAY 65 KIKV+ PVVE+DGDEMTR+IWK I++ LILPYLD+ L YYDL I+HRDATDDQVT+DAA Sbjct 3 KIKVNNPVVEIDGDEMTRIIWKQIREQLILPYLDVDLHYYDLSIQHRDATDDQVTVDAAN 62 Query 66 AIKKHGVGVKCATITPDEARVEEFNLKKMWLSPNGTIRNILGGTIFREPIVISNVPRLVP 125 AIK+HGVGVKCATITPDEARVEEF LKKMW SPNGTIRNILGG +FREPI++SNVPRLVP Sbjct 63 AIKEHGVGVKCATITPDEARVEEFGLKKMWRSPNGTIRNILGGVVFREPIIMSNVPRLVP 122 Query 126 GWTKPIVIGRHAFGDQYRATNFKVDQPGTVTLTFTPADGSAPIVHEMVSIPEDGGVVLGM 185 GWTKPI+IGRHA GDQY+AT+F V PGTVT+T+TPADG P+ E+ + P GG+ +GM Sbjct 123 GWTKPIIIGRHAHGDQYKATDFVVPGPGTVTITYTPADGGTPMEMEVANFP-GGGIAMGM 181 Query 186 YNFKESIRDFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFERVYEEEFKAQFEAA 245 YN+ ESIRDFARASF YGL+ +PVY+STKNTILKAYDG FKD F V+E EFKA+FEAA Sbjct 182 YNYDESIRDFARASFRYGLDRGYPVYMSTKNTILKAYDGRFKDIFAEVFENEFKAEFEAA 241 Query 246 GLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMTADGKT 305 GLTYEHRLIDDMVAA LKWEGGYVWACKNYDGDVQSDTVAQG+GSLGLMTSVL++ DG+T Sbjct 242 GLTYEHRLIDDMVAAALKWEGGYVWACKNYDGDVQSDTVAQGFGSLGLMTSVLLSPDGRT 301 Query 306 VEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAHKLESV 365 VEAEAAHGTVTRHYRQYQ G+ TSTNPIASI+AWTRGL HRGKLDGTP V +FA LE V Sbjct 302 VEAEAAHGTVTRHYRQYQKGEKTSTNPIASIYAWTRGLAHRGKLDGTPAVTEFADTLEKV 361 Query 366 VIATVESGKMTKDLAILIGPEQDWLNSEEFLDAIADNLEKELA 408 ++ TVE G+MTKDLA+LI + WL ++EF++A+ +NL ++LA Sbjct 362 IVDTVEGGQMTKDLALLISRDAPWLTTDEFMNALDENLARKLA 404 >gi|50955486|ref|YP_062774.1| isocitrate dehydrogenase [Leifsonia xyli subsp. xyli str. CTCB07] gi|50951968|gb|AAT89669.1| isocitrate dehydrogenase [Leifsonia xyli subsp. xyli str. CTCB07] Length=404 Score = 647 bits (1669), Expect = 0.0, Method: Compositional matrix adjust. Identities = 308/403 (77%), Positives = 346/403 (86%), Gaps = 1/403 (0%) Query 6 KIKVSGPVVELDGDEMTRVIWKLIKDMLILPYLDIRLDYYDLGIEHRDATDDQVTIDAAY 65 KIKV G VVELDGDEMTR+IWK IKD LI PYLDI L+YYDLGI+ RD TDDQ+TIDAA+ Sbjct 3 KIKVEGTVVELDGDEMTRIIWKAIKDSLIHPYLDIDLEYYDLGIQKRDETDDQITIDAAH 62 Query 66 AIKKHGVGVKCATITPDEARVEEFNLKKMWLSPNGTIRNILGGTIFREPIVISNVPRLVP 125 AI+KHGVGVKCATITPDEARVEEF LKKMW SPNGTIRNILGG +FREPI+ISN+PRLVP Sbjct 63 AIQKHGVGVKCATITPDEARVEEFGLKKMWKSPNGTIRNILGGVVFREPIIISNIPRLVP 122 Query 126 GWTKPIVIGRHAFGDQYRATNFKVDQPGTVTLTFTPADGSAPIVHEMVSIPEDGGVVLGM 185 GW KPI+IGRHAFGDQYRAT+F D PGT+TL+F P+DG E+ P GV L M Sbjct 123 GWNKPIIIGRHAFGDQYRATDFTFDGPGTLTLSFQPSDGGEAKSVEVYQAP-GAGVALAM 181 Query 186 YNFKESIRDFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFERVYEEEFKAQFEAA 245 YN ESIRDFARASF+YGL+ ++PVYLSTKNTILKAYDG FKD F+ V++ E+K +F+AA Sbjct 182 YNQDESIRDFARASFTYGLDRQYPVYLSTKNTILKAYDGRFKDLFQEVFDTEYKEKFDAA 241 Query 246 GLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMTADGKT 305 GLTYEHRLIDDMVA+ LKWEGGYVWACKNYDGDVQSDTVAQG+GSLGLMTSVL T DGK Sbjct 242 GLTYEHRLIDDMVASSLKWEGGYVWACKNYDGDVQSDTVAQGFGSLGLMTSVLTTPDGKV 301 Query 306 VEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAHKLESV 365 VEAEAAHGTVTRHYRQ+Q GKPTSTNPIASIFAWTRGL HRGKLDG ++IDF H LE V Sbjct 302 VEAEAAHGTVTRHYRQHQQGKPTSTNPIASIFAWTRGLAHRGKLDGNQQLIDFTHTLEDV 361 Query 366 VIATVESGKMTKDLAILIGPEQDWLNSEEFLDAIADNLEKELA 408 V+ TVE GKMTKDLA+L+GPEQ +L +EEFL+AI+ NL+ L Sbjct 362 VVKTVEQGKMTKDLALLVGPEQAFLTTEEFLEAISANLKALLG 404 >gi|284992784|ref|YP_003411338.1| isocitrate dehydrogenase, NADP-dependent [Geodermatophilus obscurus DSM 43160] gi|284066029|gb|ADB76967.1| isocitrate dehydrogenase, NADP-dependent [Geodermatophilus obscurus DSM 43160] Length=404 Score = 646 bits (1667), Expect = 0.0, Method: Compositional matrix adjust. Identities = 308/403 (77%), Positives = 342/403 (85%), Gaps = 1/403 (0%) Query 6 KIKVSGPVVELDGDEMTRVIWKLIKDMLILPYLDIRLDYYDLGIEHRDATDDQVTIDAAY 65 KIKV G VVELDGDEMTR+IW+ IKD LILPYLD+ L+YYDLGIE RD TDDQ+T+DAA Sbjct 3 KIKVEGTVVELDGDEMTRIIWQFIKDQLILPYLDVDLEYYDLGIEKRDETDDQITVDAAE 62 Query 66 AIKKHGVGVKCATITPDEARVEEFNLKKMWLSPNGTIRNILGGTIFREPIVISNVPRLVP 125 AIK+HGVGVKCATITPDEARVEEF LKKMW SPNGTIRNILGG IFREPI++ NVPRLVP Sbjct 63 AIKRHGVGVKCATITPDEARVEEFGLKKMWRSPNGTIRNILGGVIFREPIIMQNVPRLVP 122 Query 126 GWTKPIVIGRHAFGDQYRATNFKVDQPGTVTLTFTPADGSAPIVHEMVSIPEDGGVVLGM 185 GWTKPIV+GRHAFGDQYRAT+F+ GT+T+TF P DG PI HE+ P GGV + M Sbjct 123 GWTKPIVVGRHAFGDQYRATDFRFPGEGTLTITFQPKDGGEPIQHEVFQSP-GGGVAMAM 181 Query 186 YNFKESIRDFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFERVYEEEFKAQFEAA 245 YN ESIRDFARAS +YGL +PVYLSTKNTILKAYDG FKD F V+E EFK QFE A Sbjct 182 YNLDESIRDFARASMNYGLQRGYPVYLSTKNTILKAYDGRFKDLFAEVFESEFKDQFEQA 241 Query 246 GLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMTADGKT 305 G+TYEHRLIDDMVAA LKWEGGYVWACKNYDGDVQSDTVAQG+GSLGLMTSVLM+ DG+T Sbjct 242 GITYEHRLIDDMVAASLKWEGGYVWACKNYDGDVQSDTVAQGFGSLGLMTSVLMSPDGRT 301 Query 306 VEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAHKLESV 365 VEAEAAHGTVTRH+RQ+Q GK TSTNPIASIFAWTRGL HRGKLD TPEV FA LE V Sbjct 302 VEAEAAHGTVTRHFRQHQQGKETSTNPIASIFAWTRGLAHRGKLDNTPEVTRFAETLEKV 361 Query 366 VIATVESGKMTKDLAILIGPEQDWLNSEEFLDAIADNLEKELA 408 I TVESG+MTKDLA+LI +Q WL++++FL AI NL+K +A Sbjct 362 CIDTVESGQMTKDLALLISKDQPWLSTQDFLAAIDGNLQKAMA 404 >gi|258651518|ref|YP_003200674.1| isocitrate dehydrogenase [Nakamurella multipartita DSM 44233] gi|258554743|gb|ACV77685.1| isocitrate dehydrogenase, NADP-dependent [Nakamurella multipartita DSM 44233] Length=404 Score = 646 bits (1666), Expect = 0.0, Method: Compositional matrix adjust. Identities = 306/403 (76%), Positives = 347/403 (87%), Gaps = 1/403 (0%) Query 6 KIKVSGPVVELDGDEMTRVIWKLIKDMLILPYLDIRLDYYDLGIEHRDATDDQVTIDAAY 65 KIKV G VVELDGDEMTR+IW+ IK+ LILPYLD+ L+YYDLGIE RD T+DQ+TIDAA+ Sbjct 3 KIKVEGTVVELDGDEMTRIIWQFIKEKLILPYLDVNLEYYDLGIESRDDTNDQITIDAAH 62 Query 66 AIKKHGVGVKCATITPDEARVEEFNLKKMWLSPNGTIRNILGGTIFREPIVISNVPRLVP 125 AI+KHGVGVKCATITPDEARVEEF LKKMW SPNGTIRNILGG IFREPI+ISN+PRLVP Sbjct 63 AIQKHGVGVKCATITPDEARVEEFGLKKMWRSPNGTIRNILGGVIFREPIIISNIPRLVP 122 Query 126 GWTKPIVIGRHAFGDQYRATNFKVDQPGTVTLTFTPADGSAPIVHEMVSIPEDGGVVLGM 185 GWTKPI++GRHA+GDQYRAT+F+ GT+T+TFTP DGS PI H + P G V M Sbjct 123 GWTKPIIVGRHAYGDQYRATDFRFPGEGTLTITFTPKDGSKPIEHVVFESPSSG-VAQAM 181 Query 186 YNFKESIRDFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFERVYEEEFKAQFEAA 245 YN +SIRDFARAS +YGL+ K+PVYLSTKNTILKAYDG FKD F+ V++ EF F+ A Sbjct 182 YNLDDSIRDFARASLNYGLSRKYPVYLSTKNTILKAYDGRFKDLFQEVFDAEFIGAFKEA 241 Query 246 GLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMTADGKT 305 G+TYEHRLIDDMVA+ LKWEGGYVWACKNYDGDVQSDTVAQG+GSLGLMTSVLMT DGKT Sbjct 242 GITYEHRLIDDMVASALKWEGGYVWACKNYDGDVQSDTVAQGFGSLGLMTSVLMTPDGKT 301 Query 306 VEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAHKLESV 365 VEAEAAHGTVTRHYRQ+QAGKPTSTNPIASI+AWT GL+HRGKLDGTPEV FA LE V Sbjct 302 VEAEAAHGTVTRHYRQHQAGKPTSTNPIASIYAWTGGLKHRGKLDGTPEVTGFAEALEDV 361 Query 366 VIATVESGKMTKDLAILIGPEQDWLNSEEFLDAIADNLEKELA 408 VI TVE GKMTKDLA+L+GP+Q+WL +E+FL A+ +NL L Sbjct 362 VIKTVEGGKMTKDLALLVGPDQEWLTTEDFLVALDENLATRLG 404 Lambda K H 0.318 0.136 0.409 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 816290083944 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40