BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv3393 Length=308 Score E Sequences producing significant alignments: (Bits) Value gi|15610529|ref|NP_217910.1| nucleoside hydrolase IunH [Mycobact... 620 8e-176 gi|340628371|ref|YP_004746823.1| putative nucleoside hydrolase I... 580 9e-164 gi|296168807|ref|ZP_06850489.1| purine nucleosidase [Mycobacteri... 445 5e-123 gi|294995835|ref|ZP_06801526.1| nucleoside hydrolase iunH [Mycob... 442 3e-122 gi|183981174|ref|YP_001849465.1| inosine-uridine nucleoside hydr... 430 2e-118 gi|254776771|ref|ZP_05218287.1| inosine-uridine preferring nucle... 399 2e-109 gi|336459725|gb|EGO38646.1| Inosine-uridine nucleoside N-ribohyd... 398 6e-109 gi|118464540|ref|YP_883477.1| inosine-uridine preferring nucleos... 397 1e-108 gi|41409582|ref|NP_962418.1| IunH [Mycobacterium avium subsp. pa... 397 2e-108 gi|254823410|ref|ZP_05228411.1| inosine-uridine preferring nucle... 390 2e-106 gi|342861590|ref|ZP_08718237.1| inosine-uridine preferring nucle... 382 3e-104 gi|118469555|ref|YP_885999.1| pyrimidine-specific ribonucleoside... 382 5e-104 gi|333991855|ref|YP_004524469.1| inosine-uridine nucleoside hydr... 371 9e-101 gi|169630790|ref|YP_001704439.1| putative nucleoside hydrolase I... 369 4e-100 gi|315445827|ref|YP_004078706.1| inosine-uridine nucleoside N-ri... 365 4e-99 gi|120402535|ref|YP_952364.1| inosine/uridine-preferring nucleos... 360 2e-97 gi|145225473|ref|YP_001136151.1| inosine/uridine-preferring nucl... 360 2e-97 gi|108798149|ref|YP_638346.1| inosine/uridine-preferring nucleos... 359 3e-97 gi|126433808|ref|YP_001069499.1| inosine/uridine-preferring nucl... 351 6e-95 gi|240167861|ref|ZP_04746520.1| inosine-uridine preferring nucle... 349 4e-94 gi|339299818|gb|AEJ51928.1| nucleoside hydrolase IunH [Mycobacte... 330 2e-88 gi|317507797|ref|ZP_07965499.1| inosine-uridine preferring nucle... 315 5e-84 gi|111024186|ref|YP_707158.1| purine nucleosidase [Rhodococcus j... 301 1e-79 gi|226366429|ref|YP_002784212.1| ribonucleoside hydrolase [Rhodo... 298 7e-79 gi|296392849|ref|YP_003657733.1| inosine/uridine-preferring nucl... 298 7e-79 gi|226306579|ref|YP_002766539.1| ribonucleoside hydrolase [Rhodo... 283 2e-74 gi|333919607|ref|YP_004493188.1| Purine nucleosidase [Amycolicic... 281 8e-74 gi|229493680|ref|ZP_04387465.1| purine nucleosidase [Rhodococcus... 280 2e-73 gi|325676886|ref|ZP_08156559.1| cytidine/uridine-specific hydrol... 276 4e-72 gi|312139667|ref|YP_004007003.1| purine nucleosidase [Rhodococcu... 276 4e-72 gi|262202357|ref|YP_003273565.1| inosine/uridine-preferring nucl... 275 6e-72 gi|163839683|ref|YP_001624088.1| putative inosine-uridine prefer... 275 9e-72 gi|88855662|ref|ZP_01130325.1| putative nucleoside hydrolase [ma... 270 2e-70 gi|296139829|ref|YP_003647072.1| inosine/uridine-preferring nucl... 266 3e-69 gi|54024518|ref|YP_118760.1| putative nucleoside hydrolase [Noca... 258 1e-66 gi|343927973|ref|ZP_08767439.1| putative ribonucleoside hydrolas... 257 2e-66 gi|116670211|ref|YP_831144.1| inosine/uridine-preferring nucleos... 248 7e-64 gi|308178933|ref|YP_003918339.1| purine nucleosidase [Arthrobact... 243 3e-62 gi|325963020|ref|YP_004240926.1| inosine-uridine nucleoside N-ri... 226 3e-57 gi|257069471|ref|YP_003155726.1| Inosine-uridine nucleoside N-ri... 220 2e-55 gi|328906465|gb|EGG26240.1| inosine-uridine preferring nucleosid... 220 3e-55 gi|313836321|gb|EFS74035.1| inosine-uridine preferring nucleosid... 219 4e-55 gi|220912409|ref|YP_002487718.1| inosine/uridine-specific nucleo... 217 2e-54 gi|340770089|gb|EGR92605.1| inosine-uridine preferring nucleosid... 214 1e-53 gi|313763714|gb|EFS35078.1| inosine-uridine preferring nucleosid... 213 3e-53 gi|319949206|ref|ZP_08023293.1| inosine/uridine-preferring nucle... 213 3e-53 gi|289426046|ref|ZP_06427793.1| inosine-uridine preferring nucle... 213 3e-53 gi|313771731|gb|EFS37697.1| inosine-uridine preferring nucleosid... 213 4e-53 gi|313810553|gb|EFS48267.1| inosine-uridine preferring nucleosid... 213 4e-53 gi|314984630|gb|EFT28722.1| inosine-uridine preferring nucleosid... 213 4e-53 >gi|15610529|ref|NP_217910.1| nucleoside hydrolase IunH [Mycobacterium tuberculosis H37Rv] gi|15842986|ref|NP_338023.1| inosine-uridine preferring nucleoside hydrolase [Mycobacterium tuberculosis CDC1551] gi|31794573|ref|NP_857066.1| nucleoside hydrolase IunH [Mycobacterium bovis AF2122/97] 75 more sequence titles Length=308 Score = 620 bits (1599), Expect = 8e-176, Method: Compositional matrix adjust. Identities = 307/308 (99%), Positives = 308/308 (100%), Gaps = 0/308 (0%) Query 1 VSVVFADVDTGIDDALAVIYLLASPDADLVGIASTGGNIAVGQVCANNLSLLELCGAADI 60 +SVVFADVDTGIDDALAVIYLLASPDADLVGIASTGGNIAVGQVCANNLSLLELCGAADI Sbjct 1 MSVVFADVDTGIDDALAVIYLLASPDADLVGIASTGGNIAVGQVCANNLSLLELCGAADI 60 Query 61 PVSKGADEPLGGRWPDHPKFHGPKGIGYAELPASNRRLTDYDATTAWIAAAHSHAGDLIG 120 PVSKGADEPLGGRWPDHPKFHGPKGIGYAELPASNRRLTDYDATTAWIAAAHSHAGDLIG Sbjct 61 PVSKGADEPLGGRWPDHPKFHGPKGIGYAELPASNRRLTDYDATTAWIAAAHSHAGDLIG 120 Query 121 LVTGPLTNLALALRAEPALPRLLRRLVIMGGMFDGQPITEWNIRVDPEAASEVFTAWAGQ 180 LVTGPLTNLALALRAEPALPRLLRRLVIMGGMFDGQPITEWNIRVDPEAASEVFTAWAGQ Sbjct 121 LVTGPLTNLALALRAEPALPRLLRRLVIMGGMFDGQPITEWNIRVDPEAASEVFTAWAGQ 180 Query 181 RQLPIVCGLDLTRRVAMTPDILARLASVCGSSPVMRVIEDALRFYFESHEARGHGYLAYM 240 RQLPIVCGLDLTRRVAMTPDILARLASVCGSSPVMRVIEDALRFYFESHEARGHGYLAYM Sbjct 181 RQLPIVCGLDLTRRVAMTPDILARLASVCGSSPVMRVIEDALRFYFESHEARGHGYLAYM 240 Query 241 HDPLAAAVAMDPELLTTRTATVDVDPTGATVTDWSGKRNPNARIGMSVDPAVFFDRFVER 300 HDPLAAAVAMDPELLTTRTATVDVDPTGATVTDWSGKRNPNARIGMSVDPAVFFDRFVER Sbjct 241 HDPLAAAVAMDPELLTTRTATVDVDPTGATVTDWSGKRNPNARIGMSVDPAVFFDRFVER 300 Query 301 IGRFARRT 308 IGRFARRT Sbjct 301 IGRFARRT 308 >gi|340628371|ref|YP_004746823.1| putative nucleoside hydrolase IUNH [Mycobacterium canettii CIPT 140010059] gi|340006561|emb|CCC45747.1| putative nucleoside hydrolase IUNH (purine nucleosidase) [Mycobacterium canettii CIPT 140010059] Length=308 Score = 580 bits (1495), Expect = 9e-164, Method: Compositional matrix adjust. Identities = 287/308 (94%), Positives = 294/308 (96%), Gaps = 0/308 (0%) Query 1 VSVVFADVDTGIDDALAVIYLLASPDADLVGIASTGGNIAVGQVCANNLSLLELCGAADI 60 +SVVFADVDTGIDDALAVIYLLASPDADLVGIASTGGNIAVGQVCANNLSLLELCGAADI Sbjct 1 MSVVFADVDTGIDDALAVIYLLASPDADLVGIASTGGNIAVGQVCANNLSLLELCGAADI 60 Query 61 PVSKGADEPLGGRWPDHPKFHGPKGIGYAELPASNRRLTDYDATTAWIAAAHSHAGDLIG 120 PVSKGADEPL GRWPDH KFHGPKGIGYAELPASNRRLTDYDATTAWIAAAHSHAGDLIG Sbjct 61 PVSKGADEPLSGRWPDHLKFHGPKGIGYAELPASNRRLTDYDATTAWIAAAHSHAGDLIG 120 Query 121 LVTGPLTNLALALRAEPALPRLLRRLVIMGGMFDGQPITEWNIRVDPEAASEVFTAWAGQ 180 L TGPLTNLALALRAEPALPRLLRRLVIMGG+FDGQPITEWNIRVDPEAASEVFTAW GQ Sbjct 121 LATGPLTNLALALRAEPALPRLLRRLVIMGGVFDGQPITEWNIRVDPEAASEVFTAWTGQ 180 Query 181 RQLPIVCGLDLTRRVAMTPDILARLASVCGSSPVMRVIEDALRFYFESHEARGHGYLAYM 240 RQLPIVCGLDLT +VAMTPDILARLASVCG SPV+RVIEDALRFYFESHEARGHGYLAYM Sbjct 181 RQLPIVCGLDLTHQVAMTPDILARLASVCGPSPVLRVIEDALRFYFESHEARGHGYLAYM 240 Query 241 HDPLAAAVAMDPELLTTRTATVDVDPTGATVTDWSGKRNPNARIGMSVDPAVFFDRFVER 300 HDPLAAAVA+DP+LLTTR ATVDV P GA V DWSG R PNA+IGMSVDPAVFFDRFVER Sbjct 241 HDPLAAAVAVDPKLLTTRAATVDVGPAGAAVADWSGLRKPNAQIGMSVDPAVFFDRFVER 300 Query 301 IGRFARRT 308 IG FARRT Sbjct 301 IGHFARRT 308 >gi|296168807|ref|ZP_06850489.1| purine nucleosidase [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295896510|gb|EFG76157.1| purine nucleosidase [Mycobacterium parascrofulaceum ATCC BAA-614] Length=320 Score = 445 bits (1144), Expect = 5e-123, Method: Compositional matrix adjust. Identities = 229/317 (73%), Positives = 256/317 (81%), Gaps = 10/317 (3%) Query 1 VSVVFADVDTGIDDALAVIYLLASPDADLVGIASTGGNIAVGQVCANNLSLLELCGAADI 60 ++ VF DVDTGIDDALA+IYLLASPDAD++GIASTGGNI V QVCANNL LLELCGA I Sbjct 1 MNAVFVDVDTGIDDALALIYLLASPDADVLGIASTGGNIHVEQVCANNLGLLELCGAPSI 60 Query 61 PVSKGADEPLGGRWPDHPKFHGPKGIGYAELPASNRRLTDYDATTAWIAAAHSHAGDLIG 120 PVS+GADEPL GRW KFHGP G+GYAELPA++RR+T YDAT AW+ AA SH G L G Sbjct 61 PVSRGADEPLHGRWSHRSKFHGPSGLGYAELPATDRRVTGYDATGAWVRAARSHPGTLTG 120 Query 121 LVTGPLTNLALALRAEPALPRLLRRLVIMGGMF--DGQPITEWNIRVDPEAASEVFTAWA 178 LVTGPLTNLALALR EPALP LLRRLVIMGG F D P+ EWNIRVDPEAA+EV W+ Sbjct 121 LVTGPLTNLALALRREPALPTLLRRLVIMGGAFGPDTNPMAEWNIRVDPEAANEVLAGWS 180 Query 179 GQRQLPIVCGLDLTRRVAMTPDILARL---ASVCGSSPVMRVIEDALRFYFESHEARGHG 235 + Q PIVCGLDLTRRVAMTPDILARL A+ G S +M VIEDA+RFYFESHE RG+G Sbjct 181 RRGQPPIVCGLDLTRRVAMTPDILARLSAQATGAGGSRLMTVIEDAMRFYFESHEERGYG 240 Query 236 YLAYMHDPLAAAVAMDPELLTTRTATVDVD----PT-GATVTDWSGKRNPNARIGMSVDP 290 Y A+MHDPLAAAVA+DP+L++TR ATVDV+ PT G TV D SG R PNA IG+ VDP Sbjct 241 YTAFMHDPLAAAVALDPQLISTRAATVDVELADVPTRGVTVADMSGSRKPNALIGVHVDP 300 Query 291 AVFFDRFVERIGRFARR 307 A FFDR VER+GRF R Sbjct 301 AAFFDRLVERVGRFVNR 317 >gi|294995835|ref|ZP_06801526.1| nucleoside hydrolase iunH [Mycobacterium tuberculosis 210] Length=223 Score = 442 bits (1137), Expect = 3e-122, Method: Compositional matrix adjust. Identities = 221/223 (99%), Positives = 222/223 (99%), Gaps = 0/223 (0%) Query 1 VSVVFADVDTGIDDALAVIYLLASPDADLVGIASTGGNIAVGQVCANNLSLLELCGAADI 60 +SVVFADVDTGIDDALAVIYLLASPDADLVGIASTGGNIAVGQVCANNLSLLELCGAADI Sbjct 1 MSVVFADVDTGIDDALAVIYLLASPDADLVGIASTGGNIAVGQVCANNLSLLELCGAADI 60 Query 61 PVSKGADEPLGGRWPDHPKFHGPKGIGYAELPASNRRLTDYDATTAWIAAAHSHAGDLIG 120 PVSKGADEPLGGRWPDHPKFHGPKGIGYAELPASNRRLTDYDATTAWIAAAHSHAGDLIG Sbjct 61 PVSKGADEPLGGRWPDHPKFHGPKGIGYAELPASNRRLTDYDATTAWIAAAHSHAGDLIG 120 Query 121 LVTGPLTNLALALRAEPALPRLLRRLVIMGGMFDGQPITEWNIRVDPEAASEVFTAWAGQ 180 LVTGPLTNLALALRAEPALPRLLRRLVIMGGMFDGQPITEWNIRVDPEAASEV TAWAGQ Sbjct 121 LVTGPLTNLALALRAEPALPRLLRRLVIMGGMFDGQPITEWNIRVDPEAASEVSTAWAGQ 180 Query 181 RQLPIVCGLDLTRRVAMTPDILARLASVCGSSPVMRVIEDALR 223 RQLPIVCGLDLTRRVAMTPDILARLASVCGSSPVMRVIEDALR Sbjct 181 RQLPIVCGLDLTRRVAMTPDILARLASVCGSSPVMRVIEDALR 223 >gi|183981174|ref|YP_001849465.1| inosine-uridine nucleoside hydrolase, IunH [Mycobacterium marinum M] gi|183174500|gb|ACC39610.1| inosine-uridine nucleoside hydrolase, IunH [Mycobacterium marinum M] Length=316 Score = 430 bits (1105), Expect = 2e-118, Method: Compositional matrix adjust. Identities = 217/312 (70%), Positives = 250/312 (81%), Gaps = 8/312 (2%) Query 4 VFADVDTGIDDALAVIYLLASPDADLVGIASTGGNIAVGQVCANNLSLLELCGAADIPVS 63 VF D DTGIDDALA+IYLLAS DADLVGIASTGGN +V QVC NNL +LELC A DIPV+ Sbjct 4 VFVDADTGIDDALALIYLLASTDADLVGIASTGGNTSVDQVCTNNLGVLELCRAGDIPVA 63 Query 64 KGADEPLGGRWPDHPKFHGPKGIGYAELPASNRRLTDYDATTAWIAAAHSHAGDLIGLVT 123 +GAD+PL G+WP HGPKG+GYAELP +NR L YDA AW+ AH++ G L GLVT Sbjct 64 RGADQPLTGQWPHRANTHGPKGLGYAELPPTNRELATYDAAAAWVRMAHAYRGKLTGLVT 123 Query 124 GPLTNLALALRAEPALPRLLRRLVIMGGMF--DGQPI-TEWNIRVDPEAASEVFTAWAGQ 180 GPLTNLA ALRAEPALP +L RLVIMGGMF DG + +WNIRVDPEAASEVF AW GQ Sbjct 124 GPLTNLARALRAEPALPAMLSRLVIMGGMFDADGNDVGADWNIRVDPEAASEVFAAWTGQ 183 Query 181 RQLPIVCGLDLTRRVAMTPDILARLASVCGSSPVMRVIEDALRFYFESHEARGHGYLAYM 240 ++LPIVC L+LTR+VAMTPDILARL G S + RVI+DA+RFYFESH RG GYLAY+ Sbjct 184 QRLPIVCSLNLTRKVAMTPDILARLTCAAGPSALTRVIQDAVRFYFESHRDRGFGYLAYL 243 Query 241 HDPLAAAVAMDPELLTTRTATVDV----DPT-GATVTDWSGKRNPNARIGMSVDPAVFFD 295 HDPLAAA+A+DP+L+TT+ ATVDV PT G TV D SGK PNARIG+SVDPAVFF+ Sbjct 244 HDPLAAAIALDPQLVTTQVATVDVVLADIPTRGMTVADRSGKHPPNARIGVSVDPAVFFE 303 Query 296 RFVERIGRFARR 307 RF++R+ FARR Sbjct 304 RFIQRVAAFARR 315 >gi|254776771|ref|ZP_05218287.1| inosine-uridine preferring nucleoside hydrolase [Mycobacterium avium subsp. avium ATCC 25291] Length=346 Score = 399 bits (1026), Expect = 2e-109, Method: Compositional matrix adjust. Identities = 206/338 (61%), Positives = 251/338 (75%), Gaps = 31/338 (9%) Query 1 VSVVFADVDTGIDDALAVIYLLASPDADLVGIASTGGNIAVGQVCANNLSLLELCGAADI 60 V+ VF DVDTG+DDALA++YL ASPDAD+VGIASTGGN+AV QVC NNL LL+LCG I Sbjct 4 VTPVFVDVDTGVDDALALMYLFASPDADVVGIASTGGNVAVEQVCENNLGLLQLCGLTGI 63 Query 61 PVSKGADEPLGGRWPDHPKFHGPKGIGYAELPASNRRLTDYDATTAWIAAAHSHAGDLIG 120 PVSKG+ + L G K HGP+G+GYAELP S+ R+TD+D+ +AW+ AAH+H G+LIG Sbjct 64 PVSKGSGQTLTGPMRLPSKVHGPRGLGYAELPPSDHRVTDHDSASAWVRAAHAHPGELIG 123 Query 121 LVTGPLTNLALALRAEPALPRLLRRLVIMGGMFDGQ----PITEWNIRVDPEAASEVFTA 176 + TGPLTNLALALRAEPALP LLRRLVIMGG +D + + EWNI VDPEAA+EV Sbjct 124 VATGPLTNLALALRAEPALPTLLRRLVIMGGSYDHRGNTTAVAEWNISVDPEAAAEVLAG 183 Query 177 W----AGQRQLPIVCGLDLTRRVAMTPDILARLASVCGS------------------SPV 214 W AG+ +LPI+CGLDLTR+VAMTPD L RLA+ S +P+ Sbjct 184 WGGADAGRERLPILCGLDLTRKVAMTPDHLTRLATAADSGTRPLSADDEPGTRSAAANPL 243 Query 215 MRVIEDALRFYFESHEARGHGYLAYMHDPLAAAVAMDPELLTTRTATVDVDPTGA----- 269 +RVIEDA+RFY E++ GHGY A+MHDPLAAAVA+DP L+ TR ATV+++ TG Sbjct 244 IRVIEDAMRFYLEAYHDLGHGYQAHMHDPLAAAVALDPTLVATRPATVEIELTGTLTRAM 303 Query 270 TVTDWSGKRNPNARIGMSVDPAVFFDRFVERIGRFARR 307 TVTDWSG+R PNA IG+ VD A FFDRF+ER+G FARR Sbjct 304 TVTDWSGRREPNALIGIDVDSAAFFDRFIERVGPFARR 341 >gi|336459725|gb|EGO38646.1| Inosine-uridine nucleoside N-ribohydrolase [Mycobacterium avium subsp. paratuberculosis S397] Length=346 Score = 398 bits (1022), Expect = 6e-109, Method: Compositional matrix adjust. Identities = 206/338 (61%), Positives = 249/338 (74%), Gaps = 31/338 (9%) Query 1 VSVVFADVDTGIDDALAVIYLLASPDADLVGIASTGGNIAVGQVCANNLSLLELCGAADI 60 V+ VF DVDTG+DDALA++YL ASPDAD+VGIASTGGN+AV QVC NNL LL+LCG I Sbjct 4 VTPVFVDVDTGVDDALALMYLFASPDADVVGIASTGGNVAVEQVCENNLGLLQLCGLTGI 63 Query 61 PVSKGADEPLGGRWPDHPKFHGPKGIGYAELPASNRRLTDYDATTAWIAAAHSHAGDLIG 120 PVSKG+ + L G K HGP+G+GYAELP S+ R+TD+D+ TAW+ AAH+H G+LIG Sbjct 64 PVSKGSGQTLTGPMRLPSKVHGPRGLGYAELPPSDHRVTDHDSATAWVCAAHAHPGELIG 123 Query 121 LVTGPLTNLALALRAEPALPRLLRRLVIMGGMFDGQ----PITEWNIRVDPEAASEVFTA 176 + TGPLTNLALALRAEPALP LLRRLVIMGG +D + + EWNI VDPEAA+EV Sbjct 124 VATGPLTNLALALRAEPALPTLLRRLVIMGGSYDHRGNTTAVAEWNISVDPEAAAEVLAG 183 Query 177 WA----GQRQLPIVCGLDLTRRVAMTPDILARLASVCGSS------------------PV 214 W G+ +LPI+CGLDLTR+VAMTP L RLA+ SS P+ Sbjct 184 WGGADVGRERLPILCGLDLTRKVAMTPGHLTRLATAADSSTRPLSADDEPGTRSAAANPL 243 Query 215 MRVIEDALRFYFESHEARGHGYLAYMHDPLAAAVAMDPELLTTRTATVDVDPTGA----- 269 +RVIEDA+RFY E++ GHGY A+MHDPLAAAVA+DP L+ TR ATV+++ TG Sbjct 244 IRVIEDAMRFYLEAYHDLGHGYQAHMHDPLAAAVALDPTLVATRPATVEIELTGTLTRAM 303 Query 270 TVTDWSGKRNPNARIGMSVDPAVFFDRFVERIGRFARR 307 TVTDWSG+R PNA IG+ VD A FFDRF+ER+G FARR Sbjct 304 TVTDWSGRREPNALIGIDVDSAAFFDRFIERVGPFARR 341 >gi|118464540|ref|YP_883477.1| inosine-uridine preferring nucleoside hydrolase [Mycobacterium avium 104] gi|118165827|gb|ABK66724.1| Inosine-uridine preferring nucleoside hydrolase [Mycobacterium avium 104] Length=346 Score = 397 bits (1021), Expect = 1e-108, Method: Compositional matrix adjust. Identities = 205/338 (61%), Positives = 250/338 (74%), Gaps = 31/338 (9%) Query 1 VSVVFADVDTGIDDALAVIYLLASPDADLVGIASTGGNIAVGQVCANNLSLLELCGAADI 60 V+ VF DVDTG+DDALA++YL ASPDAD+VGIASTGGN+AV QVC NNL LL+LCG I Sbjct 4 VTPVFVDVDTGVDDALALMYLFASPDADVVGIASTGGNVAVEQVCENNLGLLQLCGLTGI 63 Query 61 PVSKGADEPLGGRWPDHPKFHGPKGIGYAELPASNRRLTDYDATTAWIAAAHSHAGDLIG 120 PVSKG+ + L G K HGP+G+GYAELP S+ R+TD+D+ +AW+ AAH+H G+LIG Sbjct 64 PVSKGSGQTLTGPMRLPSKVHGPRGLGYAELPPSDHRVTDHDSASAWVRAAHAHPGELIG 123 Query 121 LVTGPLTNLALALRAEPALPRLLRRLVIMGGMFDGQ----PITEWNIRVDPEAASEVFTA 176 + TGPLTNLALALRAEPALP LLRRLVIMGG +D + + EWNI VDPEAA+EV Sbjct 124 VATGPLTNLALALRAEPALPTLLRRLVIMGGSYDHRGNTTAVAEWNISVDPEAAAEVLAG 183 Query 177 WAG----QRQLPIVCGLDLTRRVAMTPDILARLASVCGS------------------SPV 214 W G + +LPI+CGLDLTR+VAMTPD L RLA+ S +P+ Sbjct 184 WGGADVVRERLPILCGLDLTRKVAMTPDHLTRLATAADSGTRPLSADDEPGTRSAAANPL 243 Query 215 MRVIEDALRFYFESHEARGHGYLAYMHDPLAAAVAMDPELLTTRTATVDVDPTGA----- 269 +RVIEDA+RFY E++ GHGY A+MHDPLAAAVA+DP L+ TR ATV+++ TG Sbjct 244 IRVIEDAMRFYLEAYHDLGHGYQAHMHDPLAAAVALDPTLVATRPATVEIELTGTLTRAM 303 Query 270 TVTDWSGKRNPNARIGMSVDPAVFFDRFVERIGRFARR 307 TVTDWSG+R PNA IG+ VD A FFDRF+ER+G FARR Sbjct 304 TVTDWSGRREPNALIGIDVDSAAFFDRFIERVGPFARR 341 >gi|41409582|ref|NP_962418.1| IunH [Mycobacterium avium subsp. paratuberculosis K-10] gi|41398413|gb|AAS06034.1| IunH [Mycobacterium avium subsp. paratuberculosis K-10] Length=343 Score = 397 bits (1019), Expect = 2e-108, Method: Compositional matrix adjust. Identities = 205/335 (62%), Positives = 247/335 (74%), Gaps = 31/335 (9%) Query 4 VFADVDTGIDDALAVIYLLASPDADLVGIASTGGNIAVGQVCANNLSLLELCGAADIPVS 63 VF DVDTG+DDALA++YL ASPDAD+VGIASTGGN+AV QVC NNL LL+LCG IPVS Sbjct 4 VFVDVDTGVDDALALMYLFASPDADVVGIASTGGNVAVEQVCENNLGLLQLCGLTGIPVS 63 Query 64 KGADEPLGGRWPDHPKFHGPKGIGYAELPASNRRLTDYDATTAWIAAAHSHAGDLIGLVT 123 KG+ + L G K HGP+G+GYAELP S+ R+TD+D+ TAW+ AAH+H G+LIG+ T Sbjct 64 KGSGQTLTGPMRLPSKVHGPRGLGYAELPPSDHRVTDHDSATAWVCAAHAHPGELIGVAT 123 Query 124 GPLTNLALALRAEPALPRLLRRLVIMGGMFDGQ----PITEWNIRVDPEAASEVFTAWA- 178 GPLTNLALALRAEPALP LLRRLVIMGG +D + + EWNI VDPEAA+EV W Sbjct 124 GPLTNLALALRAEPALPTLLRRLVIMGGSYDHRGNTTAVAEWNISVDPEAAAEVLAGWGG 183 Query 179 ---GQRQLPIVCGLDLTRRVAMTPDILARLASVCGSS------------------PVMRV 217 G+ +LPI+CGLDLTR+VAMTP L RLA+ SS P++RV Sbjct 184 ADVGRERLPILCGLDLTRKVAMTPGHLTRLATAADSSTRPLSADDEPGTRSAAANPLIRV 243 Query 218 IEDALRFYFESHEARGHGYLAYMHDPLAAAVAMDPELLTTRTATVDVDPTGA-----TVT 272 IEDA+RFY E++ GHGY A+MHDPLAAAVA+DP L+ TR ATV+++ TG TVT Sbjct 244 IEDAMRFYLEAYHDLGHGYQAHMHDPLAAAVALDPTLVATRPATVEIELTGTLTRAMTVT 303 Query 273 DWSGKRNPNARIGMSVDPAVFFDRFVERIGRFARR 307 DWSG+R PNA IG+ VD A FFDRF+ER+G FARR Sbjct 304 DWSGRREPNALIGIDVDSAAFFDRFIERVGPFARR 338 >gi|254823410|ref|ZP_05228411.1| inosine-uridine preferring nucleoside hydrolase [Mycobacterium intracellulare ATCC 13950] Length=344 Score = 390 bits (1001), Expect = 2e-106, Method: Compositional matrix adjust. Identities = 204/335 (61%), Positives = 244/335 (73%), Gaps = 31/335 (9%) Query 4 VFADVDTGIDDALAVIYLLASPDADLVGIASTGGNIAVGQVCANNLSLLELCGAADIPVS 63 VF DVDTG+DDALA+IYL ASPDA++VGIASTGGN+ V QVC NNL LL LC IPVS Sbjct 5 VFVDVDTGVDDALALIYLFASPDAEVVGIASTGGNVGVEQVCENNLGLLRLCEVTGIPVS 64 Query 64 KGADEPLGGRWPDHPKFHGPKGIGYAELPASNRRLTDYDATTAWIAAAHSHAGDLIGLVT 123 +G+D+ L G K HGP+G+GYAELP LTDYD+ AW+ AA +H G+LIG+ T Sbjct 65 RGSDQTLTGPMCLPSKVHGPRGLGYAELPPGGDGLTDYDSADAWVRAAKAHPGELIGVAT 124 Query 124 GPLTNLALALRAEPALPRLLRRLVIMGGMFDGQ----PITEWNIRVDPEAASEVFTAWA- 178 GPLTNLALALRAEPALP LLRRLVIMGG +D + + EWNI VDPEAA+EV AW Sbjct 125 GPLTNLALALRAEPALPSLLRRLVIMGGSYDHRGNTTAVAEWNISVDPEAAAEVLAAWGQ 184 Query 179 ---GQRQLPIVCGLDLTRRVAMTPDILARLASVCGSS------------------PVMRV 217 G+++LPI+CGLDLTR+VAMTP+ LARLA+ GS+ P++RV Sbjct 185 ETVGRQRLPILCGLDLTRKVAMTPEHLARLAATAGSTTTPLSEHDERATRSTASNPLIRV 244 Query 218 IEDALRFYFESHEARGHGYLAYMHDPLAAAVAMDPELLTTRTATVDVDPTGA-----TVT 272 IEDA RFY E++ GHGY A+MHDPLAAAVA+DP L+ TR ATVD++ TG TVT Sbjct 245 IEDATRFYLEAYHDLGHGYQAHMHDPLAAAVALDPGLVNTRPATVDIELTGTLTRAMTVT 304 Query 273 DWSGKRNPNARIGMSVDPAVFFDRFVERIGRFARR 307 DWSG+R PNA IG+ VD A FFDRF+ER+G FARR Sbjct 305 DWSGRREPNALIGIDVDAAGFFDRFIERVGPFARR 339 >gi|342861590|ref|ZP_08718237.1| inosine-uridine preferring nucleoside hydrolase [Mycobacterium colombiense CECT 3035] gi|342131079|gb|EGT84368.1| inosine-uridine preferring nucleoside hydrolase [Mycobacterium colombiense CECT 3035] Length=344 Score = 382 bits (982), Expect = 3e-104, Method: Compositional matrix adjust. Identities = 199/337 (60%), Positives = 245/337 (73%), Gaps = 31/337 (9%) Query 2 SVVFADVDTGIDDALAVIYLLASPDADLVGIASTGGNIAVGQVCANNLSLLELCGAADIP 61 S VF DVDTG+DDALA++YL ASPDA+++GIASTGGN+ V QVC NNL LL LC D+P Sbjct 3 SPVFVDVDTGVDDALALMYLFASPDAEVIGIASTGGNVGVDQVCENNLGLLALCERTDVP 62 Query 62 VSKGADEPLGGRWPDHPKFHGPKGIGYAELPASNRRLTDYDATTAWIAAAHSHAGDLIGL 121 VSKG+ E L G K HGP+G+GYA+LP + RLTDYD+ AW+ AA + G+LIG+ Sbjct 63 VSKGSGETLTGPMRLPSKVHGPRGLGYADLPPGSGRLTDYDSADAWVRAARARPGELIGV 122 Query 122 VTGPLTNLALALRAEPALPRLLRRLVIMGGMFDGQ----PITEWNIRVDPEAASEVFTAW 177 TGPLTNLALALRAEP LP LL+RLVIMGG +D + + EWNI VDPEAA+EV AW Sbjct 123 ATGPLTNLALALRAEPELPALLKRLVIMGGSYDHRGNTTAVAEWNISVDPEAAAEVLAAW 182 Query 178 A----GQRQLPIVCGLDLTRRVAMTPDILARLASVC------------------GSSPVM 215 G+++LPI+CGLDLTR+VAMTPD LARLA+ S+P++ Sbjct 183 CPENVGRQRLPILCGLDLTRKVAMTPDHLARLAAAAQSTTTRLSEHDPAGTRSTASNPLI 242 Query 216 RVIEDALRFYFESHEARGHGYLAYMHDPLAAAVAMDPELLTTRTATVDVDPTGA-----T 270 RVIEDA+RFY E++ GHGY A++HDPLAAAVA+DPEL+TTR ATV ++ TG T Sbjct 243 RVIEDAMRFYLEAYHELGHGYQAHLHDPLAAAVALDPELVTTRPATVGIELTGTLTRAMT 302 Query 271 VTDWSGKRNPNARIGMSVDPAVFFDRFVERIGRFARR 307 VTDWS +R PNA IG+ VD A FFDRF+ER+G FAR+ Sbjct 303 VTDWSDRREPNALIGIDVDAAAFFDRFIERVGPFARQ 339 >gi|118469555|ref|YP_885999.1| pyrimidine-specific ribonucleoside hydrolase RihA [Mycobacterium smegmatis str. MC2 155] gi|118170842|gb|ABK71738.1| pyrimidine-specific ribonucleoside hydrolase RihA [Mycobacterium smegmatis str. MC2 155] Length=350 Score = 382 bits (980), Expect = 5e-104, Method: Compositional matrix adjust. Identities = 205/343 (60%), Positives = 241/343 (71%), Gaps = 39/343 (11%) Query 4 VFADVDTGIDDALAVIYLLASPDADLVGIASTGGNIAVGQVCANNLSLLELCGAADIPVS 63 VFADVDTG+DDA+A+ YLLAS DADLVGIAST GNI V QVC NNL LLELCGA DIPVS Sbjct 3 VFADVDTGVDDAMALAYLLASSDADLVGIASTAGNIGVHQVCINNLGLLELCGAPDIPVS 62 Query 64 KGADEPLGGRWPDHPKFHGPKGIGYAELPASNRRLTDYDATTAWIAAAHSHAGDLIGLVT 123 +GA++PL HGP+G+GYA LPA++R LT +DA AWI AAH+H G+LIGL T Sbjct 63 RGAEQPLAAPLRTAEDTHGPEGLGYARLPATDRTLTTHDAAEAWIRAAHAHPGELIGLAT 122 Query 124 GPLTNLALALRAEPALPRLLRRLVIMGGMFDGQ----PITEWNIRVDPEAASEVFTAW-- 177 GPLTNLALA+RAEPALPRL+RRLVIMGG FD + P+ EWNI VDPE+A+EVF W Sbjct 123 GPLTNLALAMRAEPALPRLMRRLVIMGGAFDYKGNTTPVAEWNISVDPESAAEVFGGWDA 182 Query 178 --------AGQRQLPIVCGLDLTRRVAMTPDILARLASVCGS------------------ 211 A +PIV GL+LT VAMTP +L RLA+ GS Sbjct 183 AWGGRGDDAAPAHVPIVLGLNLTENVAMTPALLNRLATAAGSPSTAMSVRDERGTRSTAA 242 Query 212 SPVMRVIEDALRFYFESHEARGHGYLAYMHDPLAAAVAMDPELLTTRTATVDVDPTGA-- 269 +P++RV+EDA+RFYFE H G GYLA++HDPLAAAVA+DPEL+ R TVDV+ TG Sbjct 243 NPLIRVLEDAMRFYFEFHFDTGDGYLAHLHDPLAAAVALDPELVRCRQTTVDVELTGTLT 302 Query 270 ---TVTDWSGK--RNPNARIGMSVDPAVFFDRFVERIGRFARR 307 TV DW G R PNA IGM VDP VFFDRF+ R+G FA+R Sbjct 303 RGMTVADWRGHWGRRPNALIGMEVDPTVFFDRFISRVGAFAQR 345 >gi|333991855|ref|YP_004524469.1| inosine-uridine nucleoside hydrolase IunH [Mycobacterium sp. JDM601] gi|333487823|gb|AEF37215.1| inosine-uridine nucleoside hydrolase IunH [Mycobacterium sp. JDM601] Length=320 Score = 371 bits (952), Expect = 9e-101, Method: Compositional matrix adjust. Identities = 202/314 (65%), Positives = 243/314 (78%), Gaps = 11/314 (3%) Query 4 VFADVDTGIDDALAVIYLLASPDADLVGIASTGGNIAVGQVCANNLSLLELCGAADIPVS 63 VFADVDTG+DDA+A++YLLA A LVG+A+TGGN+AV QVC NNL+LLELCGA+ IPVS Sbjct 5 VFADVDTGVDDAVALVYLLADSRARLVGLAATGGNVAVQQVCRNNLALLELCGASGIPVS 64 Query 64 KGADEPLGGRWPDHPKFHGPKGIGYAELPASNRRLTDYDATTAWIAAAHSHAGDLIGLVT 123 +GA+ PL G HGP+G+GYAELP + RLT YDA AW AAA H G L+GLVT Sbjct 65 RGAEAPLNGPVRTAEAIHGPQGLGYAELPPGSGRLTGYDAAAAWAAAAREHPGQLVGLVT 124 Query 124 GPLTNLALALRAEPALPRLLRRLVIMGGMFDGQPI--TEWNIRVDPEAASEVFTAWA--G 179 GPLTNLALALRAEPALP LLRRLVIMGG+F G+ E+NI DPEAA+EVF+AWA Sbjct 125 GPLTNLALALRAEPALPTLLRRLVIMGGVFSGERADRAEFNIGFDPEAAAEVFSAWAAVA 184 Query 180 QRQLPIVCGLDLTRRVAMTPDILARLASVCGSSPVMRVIEDALRFYFESHEARGHGYLAY 239 ++LP+VCGLDLT+R+A+TP ILA L + SPV+R++ DALRFYFE+H+ARGHGYLAY Sbjct 185 PQRLPLVCGLDLTQRIAITPAILALLPAPT-DSPVVRLLHDALRFYFEAHDARGHGYLAY 243 Query 240 MHDPLAAAVAMDPELLTTRTATVDVDPT-----GATVTDWSGKRNPNARIGMSVDPAVFF 294 +HDPLAAAVA++P L+TTR A + V T G T+ DW+ R PNA IG+ VDPA FF Sbjct 244 LHDPLAAAVALEPGLVTTRPAAIRVVLTPEAERGRTIPDWNA-RQPNALIGVGVDPAAFF 302 Query 295 DRFVERIGRFARRT 308 DR V+RIG ARRT Sbjct 303 DRLVQRIGTLARRT 316 >gi|169630790|ref|YP_001704439.1| putative nucleoside hydrolase IunH [Mycobacterium abscessus ATCC 19977] gi|169242757|emb|CAM63785.1| Putative nucleoside hydrolase IunH [Mycobacterium abscessus] Length=343 Score = 369 bits (946), Expect = 4e-100, Method: Compositional matrix adjust. Identities = 190/334 (57%), Positives = 231/334 (70%), Gaps = 31/334 (9%) Query 4 VFADVDTGIDDALAVIYLLASPDADLVGIASTGGNIAVGQVCANNLSLLELCGAADIPVS 63 VFADVDTG+DDAL +IYLLAS DA++VGIAST GN++V VCANNL LLELC A IPVS Sbjct 4 VFADVDTGVDDALGLIYLLASEDAEIVGIASTAGNVSVDHVCANNLGLLELCKAPQIPVS 63 Query 64 KGADEPLGGRWPDHPKFHGPKGIGYAELPASNRRLTDYDATTAWIAAAHSHAGDLIGLVT 123 KG EPL HGP G+GYA LP S R LTDYD+ AW+ AAH++ G+L+GL T Sbjct 64 KGVAEPLSAALRTAEDTHGPTGLGYALLPESTRTLTDYDSAEAWVKAAHAYPGELVGLAT 123 Query 124 GPLTNLALALRAEPALPRLLRRLVIMGGMFD----GQPITEWNIRVDPEAASEVFTAW-- 177 GPLTNLALALR EP LP+LL+RLVIMGG FD P+ EWN+ VDP A +EV+ AW Sbjct 124 GPLTNLALALRTEPELPKLLKRLVIMGGSFDYPGNTTPVAEWNVVVDPGATAEVYAAWGA 183 Query 178 AGQRQLPIVCGLDLTRRVAMTPDILARLASVCG------------------SSPVMRVIE 219 AG ++LPIVCGL+LT +AMTP+ L RLA G S+ ++R IE Sbjct 184 AGVQELPIVCGLNLTETIAMTPEHLVRLADAAGATTTPLSVLDSPSSRSGASNSLLRFIE 243 Query 220 DALRFYFESHEARGHGYLAYMHDPLAAAVAMDPELLTTRTATVDVDPTG-----ATVTDW 274 DA FYFE H +G G+LA+MHDP AAAVA+DP L+ TR+ATVDV+ TG T+ DW Sbjct 244 DAAHFYFEFHMKQGEGFLAHMHDPFAAAVALDPSLVQTRSATVDVELTGDLTRAMTIADW 303 Query 275 SGK--RNPNARIGMSVDPAVFFDRFVERIGRFAR 306 G+ + PNA+I + DP VFF RF+ER+ FAR Sbjct 304 KGQWGQRPNAQIAVETDPEVFFQRFIERVSVFAR 337 >gi|315445827|ref|YP_004078706.1| inosine-uridine nucleoside N-ribohydrolase [Mycobacterium sp. Spyr1] gi|315264130|gb|ADU00872.1| Inosine-uridine nucleoside N-ribohydrolase [Mycobacterium sp. Spyr1] Length=346 Score = 365 bits (938), Expect = 4e-99, Method: Compositional matrix adjust. Identities = 191/333 (58%), Positives = 232/333 (70%), Gaps = 31/333 (9%) Query 4 VFADVDTGIDDALAVIYLLASPDADLVGIASTGGNIAVGQVCANNLSLLELCGAADIPVS 63 VF DVDTG+DDA+A+ YLLASP+ADLVGIAST GN+ V VC NNL+LLELCG IPVS Sbjct 8 VFLDVDTGVDDAMALAYLLASPEADLVGIASTAGNVGVDDVCRNNLALLELCGTTGIPVS 67 Query 64 KGADEPLGGRWPDHPKFHGPKGIGYAELPASNRRLTDYDATTAWIAAAHSHAGDLIGLVT 123 +G+ PL HGP+G+GYA LP LTD+DA AW+ AAH H G+LIG+ T Sbjct 68 RGSATPLVAPLRTAEDTHGPRGLGYARLPEPTTTLTDHDAAQAWVRAAHDHPGELIGIAT 127 Query 124 GPLTNLALALRAEPALPRLLRRLVIMGGMFDGQ----PITEWNIRVDPEAASEVFTAW-- 177 GPLTNLALALRAEPALPRLL+RLVIMGG FD + P+ EWN+ VDPE+A+E F+ W Sbjct 128 GPLTNLALALRAEPALPRLLKRLVIMGGAFDYRGNTTPVAEWNVSVDPESAAETFSVWSR 187 Query 178 AGQRQLPIVCGLDLTRRVAMTPDILARLASVCGSS------------------PVMRVIE 219 +G LPIV GL+LT MTP++L RLA GS+ P++RV+E Sbjct 188 SGTEHLPIVLGLNLTEHAEMTPELLRRLAEAAGSTSTQMSVSDVRGTASTASNPLIRVLE 247 Query 220 DALRFYFESHEARGHGYLAYMHDPLAAAVAMDPELLTTRTATVDVDPTGA-----TVTDW 274 DA+RFYFE H +G GYLA++HDPLAAAVA+D L+ R+A VDV+ TG T+ DW Sbjct 248 DAMRFYFEFHHDQGEGYLAHVHDPLAAAVALDTTLVRYRSAPVDVELTGTLTRGMTIADW 307 Query 275 SGK--RNPNARIGMSVDPAVFFDRFVERIGRFA 305 SG R PNA IG+ VDPAVFFDRF+ R+G FA Sbjct 308 SGHWGREPNALIGVEVDPAVFFDRFIARVGAFA 340 >gi|120402535|ref|YP_952364.1| inosine/uridine-preferring nucleoside hydrolase [Mycobacterium vanbaalenii PYR-1] gi|119955353|gb|ABM12358.1| Inosine/uridine-preferring nucleoside hydrolase [Mycobacterium vanbaalenii PYR-1] Length=349 Score = 360 bits (923), Expect = 2e-97, Method: Compositional matrix adjust. Identities = 190/335 (57%), Positives = 234/335 (70%), Gaps = 31/335 (9%) Query 4 VFADVDTGIDDALAVIYLLASPDADLVGIASTGGNIAVGQVCANNLSLLELCGAADIPVS 63 VF DVDTG+DDA+A++YL SPDADLVGIAST GN+ V VC NNL+LLELCG +PVS Sbjct 8 VFVDVDTGVDDAMALVYLFGSPDADLVGIASTAGNVGVDDVCRNNLALLELCGVTGVPVS 67 Query 64 KGADEPLGGRWPDHPKFHGPKGIGYAELPASNRRLTDYDATTAWIAAAHSHAGDLIGLVT 123 +G++ PL HGP+G+GYA LPA LTD+DA AW+ AA +H G+LIG+ T Sbjct 68 RGSETPLVAPLRTAEDTHGPQGLGYARLPAPTAALTDHDAAEAWVRAARAHPGELIGIAT 127 Query 124 GPLTNLALALRAEPALPRLLRRLVIMGGMFDGQ----PITEWNIRVDPEAASEVFTAW-- 177 GPLTNLALALRAEPALPRLL RLVIMGG FD + P+ EWN+ VDPE+A+EVF AW Sbjct 128 GPLTNLALALRAEPALPRLLGRLVIMGGAFDYRGNTTPVAEWNVSVDPESAAEVFAAWHR 187 Query 178 AGQRQLPIVCGLDLTRRVAMTPDILARLASVCGSS------------------PVMRVIE 219 +G LPIV GL+LT VAMTP +L+RLA GS+ PV+RV+E Sbjct 188 SGADHLPIVLGLNLTENVAMTPQLLSRLADAAGSTSTPMSALDPRGTESAASNPVIRVLE 247 Query 220 DALRFYFESHEARGHGYLAYMHDPLAAAVAMDPELLTTRTATVDVDPTGA-----TVTDW 274 DA+RFYFE H +G GYLA++HDP+AAAVA+D L+ R A VDV+ TG T+ DW Sbjct 248 DAMRFYFEFHFDQGEGYLAHLHDPVAAAVALDTALVQCRPAPVDVELTGTLTRGMTIADW 307 Query 275 SGK--RNPNARIGMSVDPAVFFDRFVERIGRFARR 307 S + R PNA IG+ VDP FFDRF+ R+G FA++ Sbjct 308 SHRWGREPNALIGVDVDPDAFFDRFIARVGAFAQQ 342 >gi|145225473|ref|YP_001136151.1| inosine/uridine-preferring nucleoside hydrolase [Mycobacterium gilvum PYR-GCK] gi|145217959|gb|ABP47363.1| Inosine/uridine-preferring nucleoside hydrolase [Mycobacterium gilvum PYR-GCK] Length=346 Score = 360 bits (923), Expect = 2e-97, Method: Compositional matrix adjust. Identities = 189/333 (57%), Positives = 232/333 (70%), Gaps = 31/333 (9%) Query 4 VFADVDTGIDDALAVIYLLASPDADLVGIASTGGNIAVGQVCANNLSLLELCGAADIPVS 63 VF DVDTG+DDA+A++YLLASP+AD+VGIAST GN+ V VC NNL+LLELCG IPVS Sbjct 8 VFLDVDTGVDDAMALVYLLASPEADVVGIASTAGNVGVDDVCRNNLALLELCGTTGIPVS 67 Query 64 KGADEPLGGRWPDHPKFHGPKGIGYAELPASNRRLTDYDATTAWIAAAHSHAGDLIGLVT 123 +G+ PL HGP+G+GYA LP LTD+DA AW+ AA H G+LIG+ T Sbjct 68 RGSATPLVAPLRTAEDTHGPRGLGYARLPEPTTTLTDHDAAQAWVRAARDHPGELIGIAT 127 Query 124 GPLTNLALALRAEPALPRLLRRLVIMGGMFDGQ----PITEWNIRVDPEAASEVFTAW-- 177 GPLTNLALALRAE ALPRLL+RLVIMGG FD + P+ EWN+ VDPE+A+E F+AW Sbjct 128 GPLTNLALALRAESALPRLLKRLVIMGGAFDYRGNTTPVAEWNVSVDPESAAETFSAWSR 187 Query 178 AGQRQLPIVCGLDLTRRVAMTPDILARLASVCGSS------------------PVMRVIE 219 +G LPIV GL+LT MTP++L RLA GS+ P++RV+E Sbjct 188 SGAGHLPIVLGLNLTEHAEMTPELLRRLAEAAGSTSTQMSVSDVRGTASTASNPLIRVLE 247 Query 220 DALRFYFESHEARGHGYLAYMHDPLAAAVAMDPELLTTRTATVDVDPTGA-----TVTDW 274 DA+RFYFE H +G GYLA++HDPLAAAVA+D L+ R+A VDV+ TG T+ DW Sbjct 248 DAMRFYFEFHHDQGEGYLAHVHDPLAAAVALDTTLVRYRSAPVDVELTGTLTRGMTIADW 307 Query 275 SGK--RNPNARIGMSVDPAVFFDRFVERIGRFA 305 SG R PNA IG+ VDPAVFFDRF+ R+G FA Sbjct 308 SGHWGREPNALIGVEVDPAVFFDRFIARVGAFA 340 >gi|108798149|ref|YP_638346.1| inosine/uridine-preferring nucleoside hydrolase [Mycobacterium sp. MCS] gi|119867245|ref|YP_937197.1| inosine/uridine-preferring nucleoside hydrolase [Mycobacterium sp. KMS] gi|108768568|gb|ABG07290.1| Inosine/uridine-preferring nucleoside hydrolase [Mycobacterium sp. MCS] gi|119693334|gb|ABL90407.1| Inosine/uridine-preferring nucleoside hydrolase [Mycobacterium sp. KMS] Length=349 Score = 359 bits (922), Expect = 3e-97, Method: Compositional matrix adjust. Identities = 187/334 (56%), Positives = 237/334 (71%), Gaps = 30/334 (8%) Query 4 VFADVDTGIDDALAVIYLLASPDADLVGIASTGGNIAVGQVCANNLSLLELCGAADIPVS 63 VFADVDTG+DDA+A++YL AS DAD+VGIAST GN+ V QVC NNL+LL+LCG D+PVS Sbjct 14 VFADVDTGVDDAMALVYLFASEDADVVGIASTAGNVGVDQVCHNNLALLDLCGTHDVPVS 73 Query 64 KGADEPLGGRWPDHPKFHGPKGIGYAELPASNRRLTDYDATTAWIAAAHSHAGDLIGLVT 123 +GAD P+ HGP+G+GYA LP+S +T YDA AW+ AA +H G+L+G+ Sbjct 74 RGADGPIASALRTAEDTHGPEGLGYAHLPSSGSTVTTYDAAEAWVRAARAHPGELVGIAV 133 Query 124 GPLTNLALALRAEPALPRLLRRLVIMGGMFDGQ----PITEWNIRVDPEAASEVFTAWAG 179 GPLTNLALA+RAEPALP LLRRLVIMGG FD + + EWN+ VDPEAA+EVF AW+ Sbjct 134 GPLTNLALAVRAEPALPTLLRRLVIMGGAFDYRGNTTAVAEWNVSVDPEAAAEVFHAWSA 193 Query 180 QRQL-PIVCGLDLTRRVAMTPDILARLASVCGS------------------SPVMRVIED 220 PIV GL+LT +A+TP +L RLA+ S +P++RV+ED Sbjct 194 PGLTPPIVLGLNLTEHIALTPTLLTRLAAAAQSPTRAMSVLDDRGTRSVAANPLIRVLED 253 Query 221 ALRFYFESHEARGHGYLAYMHDPLAAAVAMDPELLTTRTATVDVDPTGA-----TVTDWS 275 ALRFYFE H +G GYLA++HDPLAAAVA+DP+L+ R ATVDV+ TG T+ DW+ Sbjct 254 ALRFYFEFHFDQGEGYLAHLHDPLAAAVALDPDLVQYRAATVDVELTGTLTRGMTIADWN 313 Query 276 GK--RNPNARIGMSVDPAVFFDRFVERIGRFARR 307 G+ R PNA +G+ VD VFFDRF++R+G FARR Sbjct 314 GRWGRPPNALVGIGVDAGVFFDRFIDRVGLFARR 347 >gi|126433808|ref|YP_001069499.1| inosine/uridine-preferring nucleoside hydrolase [Mycobacterium sp. JLS] gi|126233608|gb|ABN97008.1| Inosine/uridine-preferring nucleoside hydrolase [Mycobacterium sp. JLS] Length=349 Score = 351 bits (901), Expect = 6e-95, Method: Compositional matrix adjust. Identities = 184/334 (56%), Positives = 235/334 (71%), Gaps = 30/334 (8%) Query 4 VFADVDTGIDDALAVIYLLASPDADLVGIASTGGNIAVGQVCANNLSLLELCGAADIPVS 63 VFADVDTG+DDA+A++YL AS DAD+VGIAST GN+ V QVC NNL+LL+LCG +PVS Sbjct 14 VFADVDTGVDDAMALVYLFASEDADVVGIASTAGNVGVDQVCHNNLALLDLCGTHGVPVS 73 Query 64 KGADEPLGGRWPDHPKFHGPKGIGYAELPASNRRLTDYDATTAWIAAAHSHAGDLIGLVT 123 +GAD P+ HGP+G+GYA LP++ +T YDA AW+ AA +H G+L+G+ Sbjct 74 RGADGPIASALRTAEDTHGPEGLGYAHLPSNGSTVTTYDAAEAWVRAARAHPGELVGIAV 133 Query 124 GPLTNLALALRAEPALPRLLRRLVIMGGMFDGQ----PITEWNIRVDPEAASEVFTAWAG 179 GPLTNLALA+RAEPALP LLRRLVIMGG FD + + EWN+ VDPEAA+EVF AW+ Sbjct 134 GPLTNLALAVRAEPALPTLLRRLVIMGGAFDYRGNTTAVAEWNVSVDPEAAAEVFHAWSA 193 Query 180 QRQL-PIVCGLDLTRRVAMTPDILARLASVCGS------------------SPVMRVIED 220 PIV GL+LT +A+TP +L RLA+ S +P++RV+ED Sbjct 194 PGLTPPIVLGLNLTEHIALTPTLLTRLAAAAQSPTRAMSVLDDRGTRSVAANPLIRVLED 253 Query 221 ALRFYFESHEARGHGYLAYMHDPLAAAVAMDPELLTTRTATVDVDPTGA-----TVTDWS 275 ALRFYFE H +G GYLA++HDPLAAAVA+ P+L+ R ATVDV+ TG T+ DW+ Sbjct 254 ALRFYFEFHFDQGEGYLAHLHDPLAAAVALYPDLVQYRAATVDVELTGTLTRGMTIADWN 313 Query 276 GK--RNPNARIGMSVDPAVFFDRFVERIGRFARR 307 G+ R PNA +G+ VD VFFDRF++R+G FARR Sbjct 314 GRWGRPPNALVGIGVDAGVFFDRFIDRVGPFARR 347 >gi|240167861|ref|ZP_04746520.1| inosine-uridine preferring nucleoside hydrolase [Mycobacterium kansasii ATCC 12478] Length=336 Score = 349 bits (895), Expect = 4e-94, Method: Compositional matrix adjust. Identities = 200/328 (61%), Positives = 241/328 (74%), Gaps = 24/328 (7%) Query 4 VFADVDTGIDDALAVIYLLASPDADLVGIASTGGNIAVGQVCANNLSLLELCGAADIPVS 63 VF DVDTG+DDALA++YLLASP+A+LVGIASTGGN+AV QVC NNL LLELC IPVS Sbjct 4 VFVDVDTGVDDALALLYLLASPEAELVGIASTGGNVAVQQVCENNLGLLELCRVTGIPVS 63 Query 64 KGADEPLGGRWPDHPKFHGPKGIGYAELPASNRRLTDYDATTAWIAAAHSHAGDLIGLVT 123 KGA L G D + HGP+G+GYAELP ++ R+T YD+ TAW+ AAH+ G+LIG+ T Sbjct 64 KGAGATLTGPMGDPSRSHGPRGLGYAELPPADARVTGYDSATAWVRAAHAFPGELIGVAT 123 Query 124 GPLTNLALALRAEPALPRLLRRLVIMGGMFDGQPITEWNIRVDPEAASEVFTAWAGQ--- 180 GPLTNLA ALRAEPALP LLRRLVIMGG +DG EWNI VDPEAA+EV A + Sbjct 124 GPLTNLATALRAEPALPALLRRLVIMGGCYDGTAAAEWNISVDPEAAAEVLAACSESTEP 183 Query 181 RQLPIVCGLDLTRRVAMTPDILARLASVCG------------------SSPVMRVIEDAL 222 ++LPI+CGLDLTR+VAMTP LARLA G S+P++R++EDA+ Sbjct 184 QRLPILCGLDLTRKVAMTPQHLARLAEAAGASTTTMSAHDPRGTRSAASNPLIRLVEDAM 243 Query 223 RFYFESHEARGHGYLAYMHDPLAAAVAMDPELLTTRTATVDVDPTGA---TVTDWSGKRN 279 RFY E+H G YLA++HDPLAAA A+DP L+ TR ATVDV+ TG T TDW+G+R Sbjct 244 RFYMEAHYDNGQEYLAHLHDPLAAAAALDPALVATRPATVDVELTGTRGMTATDWTGRRK 303 Query 280 PNARIGMSVDPAVFFDRFVERIGRFARR 307 PNA IG+ VD AVFFDRF+ R+G FARR Sbjct 304 PNALIGVGVDAAVFFDRFIARVGTFARR 331 >gi|339299818|gb|AEJ51928.1| nucleoside hydrolase IunH [Mycobacterium tuberculosis CCDC5180] Length=229 Score = 330 bits (845), Expect = 2e-88, Method: Compositional matrix adjust. Identities = 163/164 (99%), Positives = 164/164 (100%), Gaps = 0/164 (0%) Query 1 VSVVFADVDTGIDDALAVIYLLASPDADLVGIASTGGNIAVGQVCANNLSLLELCGAADI 60 +SVVFADVDTGIDDALAVIYLLASPDADLVGIASTGGNIAVGQVCANNLSLLELCGAADI Sbjct 1 MSVVFADVDTGIDDALAVIYLLASPDADLVGIASTGGNIAVGQVCANNLSLLELCGAADI 60 Query 61 PVSKGADEPLGGRWPDHPKFHGPKGIGYAELPASNRRLTDYDATTAWIAAAHSHAGDLIG 120 PVSKGADEPLGGRWPDHPKFHGPKGIGYAELPASNRRLTDYDATTAWIAAAHSHAGDLIG Sbjct 61 PVSKGADEPLGGRWPDHPKFHGPKGIGYAELPASNRRLTDYDATTAWIAAAHSHAGDLIG 120 Query 121 LVTGPLTNLALALRAEPALPRLLRRLVIMGGMFDGQPITEWNIR 164 LVTGPLTNLALALRAEPALPRLLRRLVIMGGMFDGQPITEWNIR Sbjct 121 LVTGPLTNLALALRAEPALPRLLRRLVIMGGMFDGQPITEWNIR 164 >gi|317507797|ref|ZP_07965499.1| inosine-uridine preferring nucleoside hydrolase [Segniliparus rugosus ATCC BAA-974] gi|316253916|gb|EFV13284.1| inosine-uridine preferring nucleoside hydrolase [Segniliparus rugosus ATCC BAA-974] Length=356 Score = 315 bits (808), Expect = 5e-84, Method: Compositional matrix adjust. Identities = 172/350 (50%), Positives = 223/350 (64%), Gaps = 47/350 (13%) Query 4 VFADVDTGIDDALAVIYLLASPDADLVGIASTGGNIAVGQVCANNLSLLELCGAADIPVS 63 +FADVDTGIDDA A++ LL++P ADLVG+A T GN++V QVCAN L++LEL G ADIPVS Sbjct 5 LFADVDTGIDDAWALLTLLSNPRADLVGVACTAGNVSVDQVCANTLAVLELAGRADIPVS 64 Query 64 KGADEPLG---GRWPD-HPKFHGPKGIGYAELPASNRRLTDYDATTAWIAAAHSHAGDLI 119 +G + PL G W + HG G+GYA + + T YDA AW+ AA + G+L+ Sbjct 65 QGREAPLRLAPGEWFEVADDTHGGSGLGYATVAEAQAWTTHYDAAEAWVQAARARPGELV 124 Query 120 GLVTGPLTNLALALRAEPALPRLLRRLVIMGGMFD----GQPITEWNIRVDPEAASEVFT 175 GLVTGPLTNLALALRAEP LPRLL+RLVIMGG FD P+ EWN+ VDPEAA EVF Sbjct 125 GLVTGPLTNLALALRAEPELPRLLKRLVIMGGAFDYPGNTTPVAEWNVHVDPEAAKEVFD 184 Query 176 AWA-------------GQRQLPIVCGLDLTRRVAMTPDILARLASVC------------- 209 AW+ +LP++CGL+LT R+ +TP+ L L+ + Sbjct 185 AWSEAIERGATSVLDGAPLELPLICGLNLTERIVLTPERLRTLSELVEGAGTAAMSAEDP 244 Query 210 ------GSSPVMRVIEDALRFYFESHEARGHGYLAYMHDPLAAAVAMDPELLTTRTATVD 263 +P++R++EDA RFYFE H +G GY+A+MHDP AA A+DPE++ T A+VD Sbjct 245 RGTRSTARNPLLRLLEDATRFYFEFHHDQGEGYIAHMHDPFAAEAAVDPEIVLTAPASVD 304 Query 264 VD-----PTGATVTDWSGK--RNPNARIGMSVDPAVFFDRFVERIGRFAR 306 V+ G TV DWSGK R PNA + ++ DP FFDR + R+ F R Sbjct 305 VELLGLITRGMTVADWSGKWRREPNAAVAVTTDPGAFFDRVLPRLAAFLR 354 >gi|111024186|ref|YP_707158.1| purine nucleosidase [Rhodococcus jostii RHA1] gi|110823716|gb|ABG99000.1| purine nucleosidase [Rhodococcus jostii RHA1] Length=345 Score = 301 bits (770), Expect = 1e-79, Method: Compositional matrix adjust. Identities = 176/335 (53%), Positives = 219/335 (66%), Gaps = 32/335 (9%) Query 4 VFADVDTGIDDALAVIYLLASPDADLVGIASTGGNIAVGQVCANNLSLLELCGAADIPVS 63 + DVDTGIDD+LA++YLLASP+A++VGIAST GN+ V QV ANNL+ L LCGA DI V+ Sbjct 8 LIVDVDTGIDDSLALLYLLASPEAEIVGIASTAGNVPVEQVAANNLNWLALCGAPDIEVA 67 Query 64 KGADEPLGGRWPDHPKFHGPKGIGYAELPASNRRLTDYDATTAWIAAAHSHAGDLIGLVT 123 GA PL HGP+GIGYA LP S R L++ DATT W+ +H G+L GLVT Sbjct 68 LGARVPLDCPLRTTEDTHGPQGIGYAVLPPSGRSLSERDATTLWVDLVRAHPGELTGLVT 127 Query 124 GPLTNLALALRAEPALPRLLRRLVIMGGMF----DGQPITEWNIRVDPEAASEVFTAWAG 179 GPLTNLALA+R EP LPRLLRRLV+MGG F + P +EWN+ VDPEAA EVF A++G Sbjct 128 GPLTNLALAIREEPELPRLLRRLVVMGGAFNHPGNTTPTSEWNVSVDPEAAKEVFDAFSG 187 Query 180 --QRQLPIVCGLDLTRRVAMTPDILARLASVCGSS-------------------PVMRVI 218 + PI+CGLD+T + MTPD + RLA GS+ PV+R + Sbjct 188 LPAGRRPILCGLDVTETIEMTPDHVRRLAEAAGSTPAEIISPDDGPQVRSTASNPVIRHL 247 Query 219 EDALRFYFESHEARGHGYLAYMHDPLAAAVAMDPELLTTRTATVDVD-----PTGATVTD 273 DA+RFY + H G+LA+MHDP AAAVA++P + TR ATVDV+ G TV D Sbjct 248 SDAIRFYMDFHRTHDQGFLAHMHDPFAAAVALNPAITRTRPATVDVELHGRLTRGTTVAD 307 Query 274 WSG--KRNPNARIGMSVDPAVFFDRFVERIGRFAR 306 W G R PN I + DPA FFD V+R+GRFA+ Sbjct 308 WVGHWNREPNVDIAVRTDPAAFFDDLVDRVGRFAK 342 >gi|226366429|ref|YP_002784212.1| ribonucleoside hydrolase [Rhodococcus opacus B4] gi|226244919|dbj|BAH55267.1| putative ribonucleoside hydrolase [Rhodococcus opacus B4] Length=343 Score = 298 bits (763), Expect = 7e-79, Method: Compositional matrix adjust. Identities = 175/335 (53%), Positives = 217/335 (65%), Gaps = 32/335 (9%) Query 4 VFADVDTGIDDALAVIYLLASPDADLVGIASTGGNIAVGQVCANNLSLLELCGAADIPVS 63 + DVDTGIDD+LA++YLLASP+A++ GIAST GN+ V QV ANNL+ L LCGA D+ V+ Sbjct 6 LIVDVDTGIDDSLALLYLLASPEAEIAGIASTAGNVPVEQVAANNLNWLALCGAPDVEVA 65 Query 64 KGADEPLGGRWPDHPKFHGPKGIGYAELPASNRRLTDYDATTAWIAAAHSHAGDLIGLVT 123 GA PL HGP+GIGYA LP S R L++ DATT W+ G+L GLVT Sbjct 66 LGARVPLACPLRTTEDTHGPQGIGYAVLPPSGRSLSERDATTLWVDLVRDAPGELTGLVT 125 Query 124 GPLTNLALALRAEPALPRLLRRLVIMGGMF----DGQPITEWNIRVDPEAASEVFTAWAG 179 GPLTNLALA+R EP LPRLL RLV+MGG F + P TEWN+ VDPEAA EVF A++G Sbjct 126 GPLTNLALAIREEPELPRLLHRLVVMGGAFNHPGNTTPTTEWNVSVDPEAAKEVFDAFSG 185 Query 180 --QRQLPIVCGLDLTRRVAMTPDILARLASVCGSS-------------------PVMRVI 218 + + PI+CGLD+T + MTPD + RLA GSS PV+R + Sbjct 186 LPEGRRPILCGLDVTETIEMTPDHVRRLAEAAGSSPAEIISADDGPEVRSTASNPVIRHL 245 Query 219 EDALRFYFESHEARGHGYLAYMHDPLAAAVAMDPELLTTRTATVDVD-----PTGATVTD 273 DA+RFY + H G+LA+MHDP AAAVA++P + TR ATVDV+ G TV D Sbjct 246 SDAIRFYMDFHRIHDQGFLAHMHDPFAAAVALNPAITRTRPATVDVELHGRLTRGTTVAD 305 Query 274 WSG--KRNPNARIGMSVDPAVFFDRFVERIGRFAR 306 W G R PN I +S DPA FFD V+R+GRFA+ Sbjct 306 WVGHWNREPNVDIAVSTDPAAFFDDLVDRVGRFAK 340 >gi|296392849|ref|YP_003657733.1| inosine/uridine-preferring nucleoside hydrolase [Segniliparus rotundus DSM 44985] gi|296179996|gb|ADG96902.1| Inosine/uridine-preferring nucleoside hydrolase [Segniliparus rotundus DSM 44985] Length=352 Score = 298 bits (763), Expect = 7e-79, Method: Compositional matrix adjust. Identities = 172/346 (50%), Positives = 218/346 (64%), Gaps = 42/346 (12%) Query 4 VFADVDTGIDDALAVIYLLASPDADLVGIASTGGNIAVGQVCANNLSLLELCGAADIPVS 63 VFADVDTGIDD A++ LL+ P+ADLV +A T GN+ V QVCAN L++LEL G ADIPVS Sbjct 5 VFADVDTGIDDVWALLTLLSHPEADLVAVACTAGNVHVDQVCANTLAVLELAGRADIPVS 64 Query 64 KGADEPL----GGRWPDHPKFHGPKGIGYAELPASNRRLTDYDATTAWIAAAHSHAGDLI 119 +G PL G R+ HG G+GYA + + T YDA AW AA S G+L+ Sbjct 65 QGRQAPLRLAPGERFDIADDTHGGCGLGYAAVDEAQAWTTPYDAAEAWARAARSKPGELV 124 Query 120 GLVTGPLTNLALALRAEPALPRLLRRLVIMGGMFD----GQPITEWNIRVDPEAASEVFT 175 GLVTGPLTNLALALRAEP LPRLLRRLV+MGG FD P+ EWNI VDPEAA EVF Sbjct 125 GLVTGPLTNLALALRAEPELPRLLRRLVVMGGSFDYPGNTTPVAEWNISVDPEAAKEVFD 184 Query 176 AWAGQRQ--------LPIVCGLDLTRRVAMTPDILARLASVC------------------ 209 AW+ + LP++CGL+LT R+ +TP++L +L + Sbjct 185 AWSDAVEHTPGPPIALPLICGLNLTERIILTPELLGKLGELVEGAPRPALSQNDPRGKRS 244 Query 210 -GSSPVMRVIEDALRFYFESHEARGHGYLAYMHDPLAAAVAMDPELLTTRTATVDVD--- 265 +P++R++EDA RFYFE H +G GY+A+MHDP AA A+DPE++ + A VDV+ Sbjct 245 NAHNPLLRLLEDATRFYFEFHHDQGDGYIAHMHDPFAAEAAIDPEIVLSAPAAVDVELLG 304 Query 266 --PTGATVTDWSGK--RNPNARIGMSVDPAVFFDRFVERIGRFARR 307 G TV DWSGK R PNA I ++ D FFDR + R+ F R+ Sbjct 305 LITRGMTVADWSGKWRREPNAAIAVATDTGGFFDRVIPRLAAFLRQ 350 >gi|226306579|ref|YP_002766539.1| ribonucleoside hydrolase [Rhodococcus erythropolis PR4] gi|226185696|dbj|BAH33800.1| putative ribonucleoside hydrolase [Rhodococcus erythropolis PR4] Length=344 Score = 283 bits (725), Expect = 2e-74, Method: Compositional matrix adjust. Identities = 169/335 (51%), Positives = 213/335 (64%), Gaps = 32/335 (9%) Query 4 VFADVDTGIDDALAVIYLLASPDADLVGIASTGGNIAVGQVCANNLSLLELCGAADIPVS 63 + DVDTGIDD+LA++YLLASP+A+++GIAST GN+ V QV ANNL+ L LCGA DI V+ Sbjct 7 LIVDVDTGIDDSLALLYLLASPEAEILGIASTAGNVPVEQVAANNLNWLALCGAPDIEVA 66 Query 64 KGADEPLGGRWPDHPKFHGPKGIGYAELPASNRRLTDYDATTAWIAAAHSHAGDLIGLVT 123 GA EPL + HGP+GIG+A LP S R+ + AT W+ + G L GLVT Sbjct 67 LGAREPLVIPLRTTEETHGPQGIGHAVLPDSGRKRSVRTATDLWVDLVREYPGQLTGLVT 126 Query 124 GPLTNLALALRAEPALPRLLRRLVIMGGMF----DGQPITEWNIRVDPEAASEVFTAWA- 178 GPLTNLALA+R EP LP LL+RLV+MGG F + P EWN+ VDP AA EVF A++ Sbjct 127 GPLTNLALAIRREPDLPSLLKRLVVMGGSFNYPGNTTPTAEWNVSVDPHAAKEVFDAFSV 186 Query 179 -GQRQLPIVCGLDLTRRVAMTPDILARLASVCGSSP-------------------VMRVI 218 + PI+CGL++T + M P+ + RLA GS+P V+R + Sbjct 187 VPAHRRPIICGLNVTESIEMFPEHVRRLAEAAGSTPEEIISPDDGPDVRSSASNSVIRHM 246 Query 219 EDALRFYFESHEARGHGYLAYMHDPLAAAVAMDPELLTTRTATVDVDPT-----GATVTD 273 DA+RFY E H G+LA+MHDP AAAVA+DP L T + ATVDV+ G TV D Sbjct 247 SDAIRFYMEFHREYDQGFLAHMHDPFAAAVALDPSLATLKPATVDVETESPLLIGTTVAD 306 Query 274 WSG--KRNPNARIGMSVDPAVFFDRFVERIGRFAR 306 W G KR PNA I +S DPA FFDR V R+G +AR Sbjct 307 WVGHWKREPNADIAVSTDPAEFFDRLVHRVGNYAR 341 >gi|333919607|ref|YP_004493188.1| Purine nucleosidase [Amycolicicoccus subflavus DQS3-9A1] gi|333481828|gb|AEF40388.1| Purine nucleosidase [Amycolicicoccus subflavus DQS3-9A1] Length=346 Score = 281 bits (719), Expect = 8e-74, Method: Compositional matrix adjust. Identities = 165/330 (50%), Positives = 208/330 (64%), Gaps = 31/330 (9%) Query 7 DVDTGIDDALAVIYLLASPDADLVGIASTGGNIAVGQVCANNLSLLELCGAADIPVSKGA 66 DVDTGIDD+LA++YLLASP+AD+ IA TGGN+A QV NNL+ LELCGA +I V+ GA Sbjct 8 DVDTGIDDSLALLYLLASPEADIRAIACTGGNVAARQVATNNLAWLELCGAPEIEVALGA 67 Query 67 DEPLGGRWPDHPKFHGPKGIGYAELPASNRRLTDYDATTAWIAAAHSHAGDLIGLVTGPL 126 + PL + HGP G+GYAELP R L+ A W+ A HAG L+G+VTGPL Sbjct 68 EAPLAAPLQTSEETHGPHGVGYAELPKPTRSLSSRSAADVWVDLARQHAGQLVGVVTGPL 127 Query 127 TNLALALRAEPALPRLLRRLVIMGGMFDG----QPITEWNIRVDPEAASEVFTAW--AGQ 180 TNLALAL EP LP +L+RLV+MGG F+ P+ EWNI VDPEAA VF A+ Sbjct 128 TNLALALEQEPDLPSMLKRLVVMGGAFNHPGNTTPVAEWNISVDPEAAKLVFDAFEDGTS 187 Query 181 RQLPIVCGLDLTRRVAMTPDILARLASVCG------------------SSPVMRVIEDAL 222 + PI+CGL+LT RV M P +A LA G +PV+R + DAL Sbjct 188 AEPPIICGLNLTERVIMRPGHVAELAKAAGLPPERIAADDPLGERSRCPNPVIRHLSDAL 247 Query 223 RFYFESHEARGHGYLAYMHDPLAAAVAMDPELLTTRTATVDVDPT-----GATVTDWSGK 277 RFY E H A G++A++HDP AAAVA++P+ + TR ATVDV+ T GATV DW G Sbjct 248 RFYMEFHRAYEQGFIAHIHDPFAAAVALNPQWVRTRAATVDVELTGTLTRGATVADWVGM 307 Query 278 --RNPNARIGMSVDPAVFFDRFVERIGRFA 305 R PNA I ++ DP F +ER+G +A Sbjct 308 WGRGPNADIAVATDPEAFIQHLIERVGGYA 337 >gi|229493680|ref|ZP_04387465.1| purine nucleosidase [Rhodococcus erythropolis SK121] gi|229319641|gb|EEN85477.1| purine nucleosidase [Rhodococcus erythropolis SK121] Length=344 Score = 280 bits (717), Expect = 2e-73, Method: Compositional matrix adjust. Identities = 167/335 (50%), Positives = 212/335 (64%), Gaps = 32/335 (9%) Query 4 VFADVDTGIDDALAVIYLLASPDADLVGIASTGGNIAVGQVCANNLSLLELCGAADIPVS 63 + DVDTGIDD+LA++YLLASP+A+++GIAST GN+ V QV ANNL+ L LCGA DI V+ Sbjct 7 LIVDVDTGIDDSLALLYLLASPEAEILGIASTAGNVPVEQVAANNLNWLALCGAPDIEVA 66 Query 64 KGADEPLGGRWPDHPKFHGPKGIGYAELPASNRRLTDYDATTAWIAAAHSHAGDLIGLVT 123 GA EPL + HGP+GIG+A LP S R+ + AT W+ + G L GLVT Sbjct 67 LGAREPLVIPLRTTEETHGPQGIGHAVLPDSGRKRSVRTATDLWVDLVREYPGQLTGLVT 126 Query 124 GPLTNLALALRAEPALPRLLRRLVIMGGMF----DGQPITEWNIRVDPEAASEVFTAWA- 178 GPLTNLALA+R EP LP LL+RLV+MGG F + P EWN+ VDP AA EVF A++ Sbjct 127 GPLTNLALAIRREPDLPSLLKRLVVMGGSFNYPGNTTPTAEWNVSVDPHAAKEVFDAFSV 186 Query 179 -GQRQLPIVCGLDLTRRVAMTPDILARLASVCGSSP-------------------VMRVI 218 + PI+CGL++T + M P+ + RLA GS+P V+R + Sbjct 187 VPAHRRPIICGLNVTESIEMFPEHVRRLAEAAGSTPEEIISPDDGPDVRSSASNSVIRHM 246 Query 219 EDALRFYFESHEARGHGYLAYMHDPLAAAVAMDPELLTTRTATVDVDPT-----GATVTD 273 DA+RFY E H G+LA+MHDP AAAVA+DP L T + ATVDV+ G TV D Sbjct 247 SDAIRFYMEFHREYDQGFLAHMHDPFAAAVALDPSLATLKPATVDVETESPLLIGTTVAD 306 Query 274 WSG--KRNPNARIGMSVDPAVFFDRFVERIGRFAR 306 W G +R PNA I + DPA FFDR V R+G +AR Sbjct 307 WVGHWQREPNADIAVRTDPAEFFDRLVHRVGNYAR 341 >gi|325676886|ref|ZP_08156559.1| cytidine/uridine-specific hydrolase [Rhodococcus equi ATCC 33707] gi|325552434|gb|EGD22123.1| cytidine/uridine-specific hydrolase [Rhodococcus equi ATCC 33707] Length=352 Score = 276 bits (705), Expect = 4e-72, Method: Compositional matrix adjust. Identities = 162/335 (49%), Positives = 208/335 (63%), Gaps = 32/335 (9%) Query 4 VFADVDTGIDDALAVIYLLASPDADLVGIASTGGNIAVGQVCANNLSLLELCGAADIPVS 63 + DVDTGIDD++A++YLLA DAD+V + ST GN+ QV ANNL+ LELCG DI V+ Sbjct 7 LIVDVDTGIDDSIALLYLLAREDADIVAVLSTAGNVPTAQVAANNLAWLELCGRTDIEVA 66 Query 64 KGADEPLGGRWPDHPKFHGPKGIGYAELPASNRRLTDYDATTAWIAAAHSHAGDLIGLVT 123 GAD PL HGP+GIGYAELPA R + A AW+ G+L+GLVT Sbjct 67 VGADGPLSVPLRTTEDTHGPQGIGYAELPAPELRPSGRSAADAWVELTRERPGELVGLVT 126 Query 124 GPLTNLALALRAEPALPRLLRRLVIMGGMFD----GQPITEWNIRVDPEAASEVFTAWAG 179 GPLTNLALA+RA+P LP LR LV+MGG F+ P+ EWNI VDPEAA+EVF A++ Sbjct 127 GPLTNLALAIRADPELPHRLRGLVVMGGAFEYPGNTTPVAEWNISVDPEAAAEVFAAFSA 186 Query 180 --QRQLPIVCGLDLTRRVAMTPDILARLASVCGSSPV-------------------MRVI 218 + PIVCGL+LT R+ +TPD + R A + GS+P+ +R + Sbjct 187 VPPERAPIVCGLNLTERIVLTPDHVRRFAELAGSAPIEDIEPTDPPGLRSAASNPLVRHV 246 Query 219 EDALRFYFESHEARGHGYLAYMHDPLAAAVAMDPELLTTRTATVDVDPT-----GATVTD 273 DA+RFYFE H G++A++HDP AAAVA+DP + T R ATVDV+ G TV D Sbjct 247 CDAVRFYFEFHRDHAQGFIAHLHDPFAAAVALDPSIATYRAATVDVETEGRITRGQTVAD 306 Query 274 WSG--KRNPNARIGMSVDPAVFFDRFVERIGRFAR 306 G R+PNARI D +VF + + R+ FAR Sbjct 307 RHGLWGRSPNARIAWDTDESVFLEDLITRLAAFAR 341 >gi|312139667|ref|YP_004007003.1| purine nucleosidase [Rhodococcus equi 103S] gi|311889006|emb|CBH48319.1| purine nucleosidase [Rhodococcus equi 103S] Length=352 Score = 276 bits (705), Expect = 4e-72, Method: Compositional matrix adjust. Identities = 162/335 (49%), Positives = 208/335 (63%), Gaps = 32/335 (9%) Query 4 VFADVDTGIDDALAVIYLLASPDADLVGIASTGGNIAVGQVCANNLSLLELCGAADIPVS 63 + DVDTGIDD++A++YLLA DAD+V + ST GN+ QV ANNL+ LELCG DI V+ Sbjct 7 LIVDVDTGIDDSIALLYLLAREDADIVAVLSTAGNVPTAQVAANNLAWLELCGRTDIEVA 66 Query 64 KGADEPLGGRWPDHPKFHGPKGIGYAELPASNRRLTDYDATTAWIAAAHSHAGDLIGLVT 123 GAD PL HGP+GIGYAELPA R + A AW+ G+L+GLVT Sbjct 67 VGADGPLSVPLRTTEDTHGPQGIGYAELPAPELRPSGRSAADAWVELTRERPGELVGLVT 126 Query 124 GPLTNLALALRAEPALPRLLRRLVIMGGMFD----GQPITEWNIRVDPEAASEVFTAWAG 179 GPLTNLALA+RA+P LP LR LV+MGG F+ P+ EWNI VDPEAA+EVF A++ Sbjct 127 GPLTNLALAIRADPELPHRLRGLVVMGGAFEYPGNTTPVAEWNISVDPEAAAEVFAAFSA 186 Query 180 --QRQLPIVCGLDLTRRVAMTPDILARLASVCGSSPV-------------------MRVI 218 + PIVCGL+LT R+ +TPD + R A + GS+P+ +R + Sbjct 187 VPPERAPIVCGLNLTERIVLTPDHVRRFAELAGSAPIEDIEPTDPPGLRSAASNPLVRHV 246 Query 219 EDALRFYFESHEARGHGYLAYMHDPLAAAVAMDPELLTTRTATVDVDPT-----GATVTD 273 DA+RFYFE H G++A++HDP AAAVA+DP + T R ATVDV+ G TV D Sbjct 247 CDAVRFYFEFHRDHAQGFIAHLHDPFAAAVALDPSIATYRAATVDVETEGRITRGQTVAD 306 Query 274 WSG--KRNPNARIGMSVDPAVFFDRFVERIGRFAR 306 G R+PNARI D +VF + + R+ FAR Sbjct 307 RHGLWGRSPNARIAWDTDESVFLEDLITRLAAFAR 341 >gi|262202357|ref|YP_003273565.1| inosine/uridine-preferring nucleoside hydrolase [Gordonia bronchialis DSM 43247] gi|262085704|gb|ACY21672.1| Inosine/uridine-preferring nucleoside hydrolase [Gordonia bronchialis DSM 43247] Length=353 Score = 275 bits (703), Expect = 6e-72, Method: Compositional matrix adjust. Identities = 166/334 (50%), Positives = 208/334 (63%), Gaps = 31/334 (9%) Query 4 VFADVDTGIDDALAVIYLLASPDADLVGIASTGGNIAVGQVCANNLSLLELCGAADIPVS 63 +F D DTGIDD+LA++YLLA D DLVG+AST GN+ V V ANNL+ L +CG ++IPV Sbjct 6 LFFDCDTGIDDSLALLYLLARRDVDLVGVASTAGNVPVDVVVANNLAWLAMCGRSEIPVH 65 Query 64 KGADEPLGGRWPDHPKFHGPKGIGYAELPASNRRLTDYDATTAWIAAAHSHAGDLIGLVT 123 G+ PL HGP G+GYAELPA+ + A AWI AA +H G+L+GLVT Sbjct 66 VGSPTPLSVPLMTTEDTHGPLGVGYAELPAATAPASPIGAADAWIDAARAHPGELVGLVT 125 Query 124 GPLTNLALALRAEPALPRLLRRLVIMGGMF----DGQPITEWNIRVDPEAASEVFTAWA- 178 GPLT+LA A+R +P LP LLRRLVIMGG F + P+ EWN+ VDPEAA+EVF A+ Sbjct 126 GPLTSLATAVRRDPQLPSLLRRLVIMGGAFHTHGNTTPVAEWNVAVDPEAAAEVFDAFGI 185 Query 179 GQRQLPIVCGLDLTRRVAMTPDILARLASVCGSS-------------------PVMRVIE 219 G PIVC LDLT +AMTPD L RLA+ GS+ PV+R + Sbjct 186 GDAPAPIVCALDLTETIAMTPDHLVRLAAAAGSTPLEYPDPGDEPGLRSVADNPVVRHLT 245 Query 220 DALRFYFESHEARGHGYLAYMHDPLAAAVAMDPELLTTRTATVDVDPTGA-----TVTDW 274 DA+RFYFE H+ GY+A+MHDP AA VA+ P+++TT A V V+ TG TV D Sbjct 246 DAVRFYFEFHDLHDEGYIAHMHDPFAAIVAIAPDIVTTVGARVAVELTGTHTRGMTVADE 305 Query 275 SGKR--NPNARIGMSVDPAVFFDRFVERIGRFAR 306 PNARI + D FD +ERIG FA+ Sbjct 306 RSMTPGAPNARIATATDVDAVFDELLERIGAFAK 339 >gi|163839683|ref|YP_001624088.1| putative inosine-uridine preferring nucleoside hydrolase [Renibacterium salmoninarum ATCC 33209] gi|162953159|gb|ABY22674.1| putative inosine-uridine preferring nucleoside hydrolase [Renibacterium salmoninarum ATCC 33209] Length=341 Score = 275 bits (702), Expect = 9e-72, Method: Compositional matrix adjust. Identities = 164/336 (49%), Positives = 209/336 (63%), Gaps = 34/336 (10%) Query 4 VFADVDTGIDDALAVIYLLASPDADLVGIASTGGNIAVGQVCANNLSLLELCGAADIPVS 63 + DVDTGIDD+LA++YLLA DA+++GI+ T GN+ QV NNL+ LELCG I V+ Sbjct 5 LLIDVDTGIDDSLALLYLLAHDDAEILGISCTAGNVPAQQVAINNLAWLELCGRTGIEVA 64 Query 64 KGADEPLGGRWPDHPKFHGPKGIGYAELPASNRRLTDYDATTAWIAAAHSHAGDLIGLVT 123 GA+ PL + HGP+GIGYAELPA L+ AT WI S G++IGLVT Sbjct 65 LGAEVPLLAPLMTTEETHGPQGIGYAELPAPVTPLSPRHATQLWIDTVRSRPGEVIGLVT 124 Query 124 GPLTNLALALRAEPALPRLLRRLVIMGGMF----DGQPITEWNIRVDPEAASEVFTAWA- 178 GPLTNLALA++ EP LP LL+RLV+MGG F + P +EWN+ VDPE+A VF A++ Sbjct 125 GPLTNLALAIKLEPELPLLLKRLVVMGGAFNYPGNTTPCSEWNVAVDPESAKLVFDAFSV 184 Query 179 --GQRQLPIVCGLDLTRRVAMTPDILARLASVCGSSPV-------------------MRV 217 +RQ PI+C LD+T V MTP LA LA GS+PV +R Sbjct 185 LPPERQ-PIICPLDVTETVIMTPQHLAELAVAAGSTPVETPDQDDPAGTRSQASNPLVRH 243 Query 218 IEDALRFYFESHEARGHGYLAYMHDPLAAAVAMDPELLTTRTATVDVD-----PTGATVT 272 DA+RFYFE H A G GY+++MHDP AAAVA+DP L T R ATVDV+ GAT+ Sbjct 244 FSDAIRFYFEFHAAEGQGYISHMHDPFAAAVALDPSLATLRQATVDVELGGTLSRGATIA 303 Query 273 DWSGK--RNPNARIGMSVDPAVFFDRFVERIGRFAR 306 DW G+ R NA + + +P VFFD + R+ AR Sbjct 304 DWRGQWGRPKNAWVAVKTEPKVFFDDLIRRVAELAR 339 >gi|88855662|ref|ZP_01130325.1| putative nucleoside hydrolase [marine actinobacterium PHSC20C1] gi|88814986|gb|EAR24845.1| putative nucleoside hydrolase [marine actinobacterium PHSC20C1] Length=343 Score = 270 bits (690), Expect = 2e-70, Method: Compositional matrix adjust. Identities = 161/332 (49%), Positives = 210/332 (64%), Gaps = 32/332 (9%) Query 7 DVDTGIDDALAVIYLLASPDADLVGIASTGGNIAVGQVCANNLSLLELCGAADIPVSKGA 66 DVDTGIDD+LA++YLLASP+A+++GI T GN+ QV NNL+ LELCG+ DI V+ G+ Sbjct 8 DVDTGIDDSLALLYLLASPEAEILGITCTSGNVPARQVAINNLAWLELCGSPDIEVALGS 67 Query 67 DEPLGGRWPDHPKFHGPKGIGYAELPASNRRLTDYDATTAWIAAAHSHAGDLIGLVTGPL 126 + P+ + HG +GIG+A L A R +++ AT WI A + G+++GLVTGPL Sbjct 68 EVPILAPLMTTEETHGLQGIGHAVLDAPARSISERHATQVWIENARARPGEVVGLVTGPL 127 Query 127 TNLALALRAEPALPRLLRRLVIMGGMFDGQ----PITEWNIRVDPEAASEVFTAWAG--Q 180 TNLALALR EP LPRLL+RLVIMGG F+ P TEWNI VDPE+A VF A++G Sbjct 128 TNLALALRIEPELPRLLKRLVIMGGAFNHAGNTLPTTEWNIAVDPESAKIVFDAFSGLPA 187 Query 181 RQLPIVCGLDLTRRVAMTPDILARLASVC-------------------GSSPVMRVIEDA 221 + PIVC LD+T + M P + RLA S+P++R + DA Sbjct 188 ERRPIVCALDVTEFIEMKPHHIERLARESLSSPAEIIAESDVDGTRSQASNPLIRHLSDA 247 Query 222 LRFYFESHEARGHGYLAYMHDPLAAAVAMDPELLTTRTATVDVD-----PTGATVTDWSG 276 +RFY E H+A G+LA+MHDP AAA+A+ PEL +R ATVDV+ G TV DW G Sbjct 248 VRFYMEFHQAHDQGFLAHMHDPFAAAIALHPELGQSRPATVDVELAGTLTRGQTVADWRG 307 Query 277 K--RNPNARIGMSVDPAVFFDRFVERIGRFAR 306 R PNA I ++ DPA FFD +ER+ AR Sbjct 308 MWGREPNADIVVATDPAAFFDHLIERVSSLAR 339 >gi|296139829|ref|YP_003647072.1| inosine/uridine-preferring nucleoside hydrolase [Tsukamurella paurometabola DSM 20162] gi|296027963|gb|ADG78733.1| Inosine/uridine-preferring nucleoside hydrolase [Tsukamurella paurometabola DSM 20162] Length=345 Score = 266 bits (680), Expect = 3e-69, Method: Compositional matrix adjust. Identities = 156/339 (47%), Positives = 199/339 (59%), Gaps = 38/339 (11%) Query 4 VFADVDTGIDDALAVIYLLASPDADLVGIASTGGNIAVGQVCANNLSLLELCGAADIPVS 63 V D DTG+DD+LA++YLLA P+ DL+GI ST GN+ QV NNL+ L+L G DI V Sbjct 6 VLFDCDTGVDDSLALLYLLAQPEVDLLGIVSTAGNVPGPQVVENNLAWLDLLGRNDIDVF 65 Query 64 KGADEPLGGRWPDHPKFHGPKGIGYAELPASNRRLTDYDATTAWIAAAHSHAGDLIGLVT 123 G+D P+ + HGP G+GYAELP R +D AW +H G+++GLVT Sbjct 66 VGSDSPVSAPLITTEETHGPFGVGYAELPPPTRTPSDRSGAQAWSEITRAHPGEVVGLVT 125 Query 124 GPLTNLALALRAEPALPRLLRRLVIMGGMF----DGQPITEWNIRVDPEAASEVFTAW-- 177 GP TNLALALR +P + LRRLVIMGG+F + P +EWN+ VDPE+ EV A+ Sbjct 126 GPCTNLALALRDDPGILARLRRLVIMGGVFWHPGNTTPTSEWNVAVDPESLWEVLRAYGE 185 Query 178 --AGQRQLPIVCGLDLTRRVAMTPDILARLASVCGSSP-------------------VMR 216 LPI+C LDLT + +TPD + RLA GSSP V+R Sbjct 186 LDGTGTALPILCPLDLTETIELTPDHVLRLADAAGSSPAEVLDPEDADGTRSTASNSVVR 245 Query 217 VIEDALRFYFESHEARGHGYLAYMHDPLAAAVAMDPELLTTRTATVDVDPTGA-----TV 271 I DA+RFYFE H GY+A+MHDP AAAVA+DP + TR TVDV+ +GA TV Sbjct 246 AISDAVRFYFEFHRDHDLGYIAHMHDPFAAAVALDPTIARTRAYTVDVELSGALTRGTTV 305 Query 272 TD----WSGKRNPNARIGMSVDPAVFFDRFVERIGRFAR 306 D W+ R A+I +S DP FFD ++ I R AR Sbjct 306 ADVHRAWN--RPDTAQIAVSADPVAFFDDMLDSIARLAR 342 >gi|54024518|ref|YP_118760.1| putative nucleoside hydrolase [Nocardia farcinica IFM 10152] gi|54016026|dbj|BAD57396.1| putative nucleoside hydrolase [Nocardia farcinica IFM 10152] Length=355 Score = 258 bits (658), Expect = 1e-66, Method: Compositional matrix adjust. Identities = 169/335 (51%), Positives = 214/335 (64%), Gaps = 32/335 (9%) Query 4 VFADVDTGIDDALAVIYLLASPDADLVGIASTGGNIAVGQVCANNLSLLELCGAADIPVS 63 + DVDTGIDD+LA++YLLASP+A++VGIA+T GN++ QV ANNL+ L++C A I V+ Sbjct 5 IIVDVDTGIDDSLALLYLLASPEAEIVGIAATAGNVSAAQVAANNLAWLDVCRAPAIEVA 64 Query 64 KGADEPLGGRWPDHPKFHGPKGIGYAELPASNRRLTDYDATTAWIAAAHSHAGDLIGLVT 123 GA PL HGP+G+GYAELP S R L+D A W+ A +H G + GL T Sbjct 65 LGAAAPLAIPLRTTEDTHGPQGVGYAELPTSARPLSDRSAAQLWVDLARAHPGQITGLCT 124 Query 124 GPLTNLALALRAEPALPRLLRRLVIMGGMF----DGQPITEWNIRVDPEAASEVFTAW-- 177 GPLTNLALALR EPALP LLRRLV+MGG F + P EWN+ VDPEAA VF A+ Sbjct 125 GPLTNLALALRLEPALPLLLRRLVVMGGAFNHPGNTTPTNEWNVHVDPEAAKAVFDAFSA 184 Query 178 AGQRQLPIVCGLDLTRRVAMTPDILARLASVCGSS-------------------PVMRVI 218 A + P++C LD+T + M P LA LA GS+ PV+R + Sbjct 185 APPERRPLICALDITETIEMHPHHLAELARRAGSTPVEQPAPTDPPGTRSTAANPVIRHV 244 Query 219 EDALRFYFESHEARGHGYLAYMHDPLAAAVAMDPELLTTRTATVDVDPTG-----ATVTD 273 DA+RFYFE H+A GYLA+MHDP AAAVA+DP L R ATVDV+ TG TV D Sbjct 245 TDAVRFYFEFHDAYDQGYLAHMHDPFAAAVALDPALARVRPATVDVELTGTITRATTVAD 304 Query 274 WSGK--RNPNARIGMSVDPAVFFDRFVERIGRFAR 306 W+G R NA I + DPA+FF+R ++R+G +AR Sbjct 305 WAGMWGRPFNADIVLGTDPALFFERMIDRVGAYAR 339 >gi|343927973|ref|ZP_08767439.1| putative ribonucleoside hydrolase [Gordonia alkanivorans NBRC 16433] gi|343762196|dbj|GAA14365.1| putative ribonucleoside hydrolase [Gordonia alkanivorans NBRC 16433] Length=345 Score = 257 bits (657), Expect = 2e-66, Method: Compositional matrix adjust. Identities = 157/335 (47%), Positives = 199/335 (60%), Gaps = 31/335 (9%) Query 4 VFADVDTGIDDALAVIYLLASPDADLVGIASTGGNIAVGQVCANNLSLLELCGAADIPVS 63 +F D DTGIDD++A++YLLA D DLVGIAST GN+ V V NNL+ LELCG ++PV Sbjct 5 LFFDCDTGIDDSVALLYLLARADVDLVGIASTAGNVPVDVVTTNNLAWLELCGRPEVPVH 64 Query 64 KGADEPLGGRWPDHPKFHGPKGIGYAELPASNRRLTDYDATTAWIAAAHSHAGDLIGLVT 123 G PL HGP G+G+A LP + DA AWI A+ +H G+L+GLVT Sbjct 65 VGPAAPLVAELMTTEDTHGPLGVGHATLPTPTSTPSHLDAPDAWIEASRTHDGELVGLVT 124 Query 124 GPLTNLALALRAEPALPRLLRRLVIMGGMF----DGQPITEWNIRVDPEAASEVFTAWAG 179 GPLT+LA A+R +PALP L RLVIMGG F + P +EWN+ VDPEAA+EVF A+ Sbjct 125 GPLTSLATAIRRDPALPARLHRLVIMGGAFHTHGNTTPTSEWNVAVDPEAAAEVFAAFGT 184 Query 180 Q-RQLPIVCGLDLTRRVAMTPDILARLASVCGSSP-------------------VMRVIE 219 PIVC LDLT +V +TP + RL++ GSSP ++R + Sbjct 185 DGAPEPIVCALDLTEQVVLTPGHVVRLSAAAGSSPLERPDPGDERGLRSVADNEIIRHLT 244 Query 220 DALRFYFESHEARGHGYLAYMHDPLAAAVAMDPELLTTRTATVDVDPTGA-----TVTD- 273 DALRFYFE H GY+A++HDP AA VA++P+L+TT A VDV+ G TV D Sbjct 245 DALRFYFEFHHDHDEGYIAHLHDPFAAMVALNPDLVTTIPARVDVELVGTLTRGMTVADE 304 Query 274 -WSGKRNPNARIGMSVDPAVFFDRFVERIGRFARR 307 W PNARI + D F +E IG F R Sbjct 305 RWMSPLGPNARIATATDLDAVFHDLIETIGAFVRN 339 >gi|116670211|ref|YP_831144.1| inosine/uridine-preferring nucleoside hydrolase [Arthrobacter sp. FB24] gi|116610320|gb|ABK03044.1| Inosine/uridine-preferring nucleoside hydrolase [Arthrobacter sp. FB24] Length=340 Score = 248 bits (634), Expect = 7e-64, Method: Compositional matrix adjust. Identities = 149/335 (45%), Positives = 194/335 (58%), Gaps = 31/335 (9%) Query 4 VFADVDTGIDDALAVIYLLASPDADLVGIASTGGNIAVGQVCANNLSLLELCGAADIPVS 63 V DVDTGIDDALA++YLL+ PD L I T GN+ QV NNL+LLELCG + + V+ Sbjct 4 VLMDVDTGIDDALALVYLLSRPDVRLQAITCTAGNVGARQVALNNLALLELCGTSGVEVA 63 Query 64 KGADEPLGGRWPDHPKFHGPKGIGYAELPASNRRLTDYDATTAWIAAAHSHAGDLIGLVT 123 GA+ PL + HGP+GIGYAELP +++++ A W+ H G++ GL+T Sbjct 64 IGAEVPLEIPLVTTEETHGPQGIGYAELPVPAQQISERHAVDVWVDEVRKHPGEITGLIT 123 Query 124 GPLTNLALALRAEPALPRLLRRLVIMGGMFDGQ----PITEWNIRVDPEAASEVFTAWAG 179 GPLTN ALALR EP LP+LL+ LVIMGG F Q P EWN+ VDP AA EVF A+ G Sbjct 124 GPLTNFALALRREPELPQLLKGLVIMGGCFYYQGNTTPTAEWNVSVDPHAAKEVFAAYRG 183 Query 180 --QRQLPIVCGLDLTRRVAMTPDILARLASVCGS------------------SPVMRVIE 219 + +LP+VC L+ T V M P+ L RLA G+ +P++ + Sbjct 184 LPEDKLPVVCALETTELVEMRPEHLQRLAEAAGTGPELVLPDQPEGLRSSSGNPLVACLS 243 Query 220 DALRFYFESHEARGHGYLAYMHDPLAAAVAMDPELLTTRTATVDVDP-----TGATVTDW 274 DA+RFY E H G++A++HD AA VA+ T R ATVDV+ G TV D+ Sbjct 244 DAIRFYMEFHRLYDQGFVAHVHDAFAACVAVGRTEYTARLATVDVETGSALLMGTTVADY 303 Query 275 SGKRN--PNARIGMSVDPAVFFDRFVERIGRFARR 307 G PNARI S +P FD + +G ARR Sbjct 304 RGLWGLPPNARIVTSNNPKQCFDELINSVGALARR 338 >gi|308178933|ref|YP_003918339.1| purine nucleosidase [Arthrobacter arilaitensis Re117] gi|307746396|emb|CBT77368.1| putative purine nucleosidase [Arthrobacter arilaitensis Re117] Length=365 Score = 243 bits (620), Expect = 3e-62, Method: Compositional matrix adjust. Identities = 148/342 (44%), Positives = 194/342 (57%), Gaps = 38/342 (11%) Query 4 VFADVDTGIDDALAVIYLLASPDADLVGIASTGGNIAVGQVCANNLSLLELCGAADIPVS 63 + D DTGIDDALA+ YL A + + + ST GN+ V QV ANN +LL+LCG +++PV Sbjct 19 LLIDCDTGIDDALALAYLCALDNVQIEAVTSTPGNVDVEQVAANNSALLKLCGKSEVPVL 78 Query 64 KGADEPLGGRWPDHPKFHGPKGIGYAELPASN-RRLTDYDATTAWIAAAHSHAGDLIGLV 122 GA EPL P+ HGP+G+GYA LP + + ++DA +WI AA ++ G+L L+ Sbjct 79 SGAREPLEIPLVTTPETHGPQGVGYATLPDPDPSTIANHDAVDSWIEAARANPGELTVLL 138 Query 123 TGPLTNLALALRAEPALPRLLRRLVIMGGMFDGQ----PITEWNIRVDPEAASEVFTAWA 178 + PLTN ALALR EP LP LLR++VIMGG F Q P EWN VDP AA EVF A+ Sbjct 139 SAPLTNFALALRREPKLPWLLRKVVIMGGAFYHQGNTTPTAEWNTHVDPHAAKEVFAAYT 198 Query 179 G-------QRQLPIVCGLDLTRRVAMTPDILARLASVCG-------------------SS 212 +LPIVC LD T R M P+ LA+LA G S+ Sbjct 199 AAAEQGIESEKLPIVCSLDTTERFEMQPEFLAKLAEEAGCEEPEWVLASDAEGTLSKASN 258 Query 213 PVMRVIEDALRFYFESHEARGHGYLAYMHDPLAAAVAMDPELLTTRTATVDVDPT----- 267 P++R + DALRFYFE H GY+A++HD AA VA TR AT+DV+ Sbjct 259 PLVRYLSDALRFYFEFHRHYDQGYIAHVHDYFAAGVAAGTLEYETRPATIDVETESQLLF 318 Query 268 GATVTDWSG--KRNPNARIGMSVDPAVFFDRFVERIGRFARR 307 G TV D+ G + NA + DP F+ V+R+G AR+ Sbjct 319 GTTVADFRGLWGKPANAHVVSRNDPKAGFEELVKRLGELARK 360 >gi|325963020|ref|YP_004240926.1| inosine-uridine nucleoside N-ribohydrolase [Arthrobacter phenanthrenivorans Sphe3] gi|323469107|gb|ADX72792.1| Inosine-uridine nucleoside N-ribohydrolase [Arthrobacter phenanthrenivorans Sphe3] Length=343 Score = 226 bits (576), Expect = 3e-57, Method: Compositional matrix adjust. Identities = 146/338 (44%), Positives = 184/338 (55%), Gaps = 32/338 (9%) Query 1 VSVVFADVDTGIDDALAVIYLLASPDADLVGIASTGGNIAVGQVCANNLSLLELCGAADI 60 ++ DVDTGIDDALA+ YL A PD + V + +T GN+ QV N L+LLELCG + Sbjct 1 MTAFLLDVDTGIDDALAIAYLAALPDTEFVSVTATPGNVDADQVARNTLALLELCGRPGV 60 Query 61 PVSKGADEPLGGRWPDHPKFHGPKGIGYAELPASNRRLTDYDATTAWIAAAHSHAGDLIG 120 V+ GA PL P+ HGP+GIGYA LP ++ +A W+ A + G+L Sbjct 61 EVAIGARGPLAIPLLTTPETHGPQGIGYAVLPDPAGAVSGRNAVDLWVEHARARPGELTA 120 Query 121 LVTGPLTNLALALRAEPALPRLLRRLVIMGGMFDGQ----PITEWNIRVDPEAASEVFTA 176 L+T PLTN ALALR EP LP LL ++VIMGG F Q P EWN VDP AA EV+ A Sbjct 121 LITAPLTNFALALRQEPRLPELLAKVVIMGGSFYYQGNTTPTAEWNTHVDPHAAKEVYAA 180 Query 177 WAGQ--RQLPIVCGLDLTRRVAMTPDILARLASVCGS-------------------SPVM 215 +AGQ +LPIVC LD T R+ + P L +LA G+ + ++ Sbjct 181 FAGQPLEKLPIVCSLDTTERMELHPAHLRQLAEAAGAGVPEDVLPEQPEGLHSTSDNLLV 240 Query 216 RVIEDALRFYFESHEARGHGYLAYMHDPLAAAVAMDPELLTTRTATVDVDP-----TGAT 270 R + DALRFYFE H GYLA++HD AA VA R A VDV+ G T Sbjct 241 RHLSDALRFYFEFHRRYDQGYLAHVHDYFAAGVAAGTLDFQARPAAVDVETGSEMLMGTT 300 Query 271 VTDWSG--KRNPNARIGMSVDPAVFFDRFVERIGRFAR 306 V D+ G R PNAR+ P F V +GR AR Sbjct 301 VADFRGLWGRPPNARVVSLNYPGAAFRELVSSVGRLAR 338 >gi|257069471|ref|YP_003155726.1| Inosine-uridine nucleoside N-ribohydrolase [Brachybacterium faecium DSM 4810] gi|256560289|gb|ACU86136.1| Inosine-uridine nucleoside N-ribohydrolase [Brachybacterium faecium DSM 4810] Length=324 Score = 220 bits (560), Expect = 2e-55, Method: Compositional matrix adjust. Identities = 134/308 (44%), Positives = 175/308 (57%), Gaps = 14/308 (4%) Query 4 VFADVDTGIDDALAVIYLLASPDADLVGIASTGGNIAVGQVCANNLSLLELCGAADIPVS 63 + D DTGIDDA+A+ YL A P A++ GI STGGN+ VG V NNL L EL G D P++ Sbjct 5 LLVDCDTGIDDAIALTYLAAHPGAEIAGIVSTGGNVEVGAVHRNNLVLNELLGV-DAPIA 63 Query 64 KGADEPLGGRWPDHPKFHGPKGIGYAELPASNRRLTDYDATTAWIAAAHSHAGDLIGLVT 123 +GA+ PL HGP G+G+A LP R W+ A G+L+GLV Sbjct 64 RGAERPLVQEPMYADDTHGPGGLGHAVLPDPTRTGDARTGAQLWVDLARQRPGELVGLVL 123 Query 124 GPLTNLALALRAEPALPRLLRRLVIMGGMFDGQ----PITEWNIRVDPEAASEVFTAWAG 179 GP TNLALAL EP LPRLLRRL +MGG + P +EWNI VDPEAA V TA++ Sbjct 124 GPHTNLALALEIEPELPRLLRRLHVMGGAIHHRGNTGPTSEWNIAVDPEAAQRVLTAFST 183 Query 180 QRQLPIVCGLDLTRRVAMTPDILARLASVCGSS--PVMRVIEDALRFYFESHEARGHGYL 237 + P++ L+ T V T R++++ + PV ++ DALRFYFE HEA G G+ Sbjct 184 AARRPVLGSLEATESVRFTQGTFDRVSALEAGTGHPVAGILADALRFYFEFHEADGFGWT 243 Query 238 AYMHDPLAAAVAMDPELLTTRTATVDVD-----PTGATVTDWSGK--RNPNARIGMSVDP 290 A++HDPL AA A+ + TR VDV+ G TV D G+ R PN + V P Sbjct 244 AHVHDPLVAAHAVTGDFAGTRPLAVDVELAGTLTRGQTVGDELGRWGRAPNVEVLTDVRP 303 Query 291 AVFFDRFV 298 F + + Sbjct 304 QEFIEHLL 311 >gi|328906465|gb|EGG26240.1| inosine-uridine preferring nucleoside hydrolase [Propionibacterium humerusii P08] Length=328 Score = 220 bits (560), Expect = 3e-55, Method: Compositional matrix adjust. Identities = 130/306 (43%), Positives = 172/306 (57%), Gaps = 13/306 (4%) Query 4 VFADVDTGIDDALAVIYLLASPDADLVGIASTGGNIAVGQVCANNLSLLELCGAADIPVS 63 V D D GIDDA A+ YL D + VG+ +T GN+ V N L L EL G D+PV+ Sbjct 17 VLLDCDPGIDDAFALAYLACRHDVETVGVVTTAGNVGQDDVLRNALGLTELLGM-DVPVA 75 Query 64 KGADEPLGGRWPDHPKFHGPKGIGYAELPASNRRLTDYDATTAWIAAAHSHAGDLIGLVT 123 +GAD PL + HGP G+G+A+L RR W+ AH +AG+L+G+ T Sbjct 76 RGADVPLVEPMMTAEETHGPHGLGHAQLGECGRRSDVRSGAQLWVDLAHRYAGELVGITT 135 Query 124 GPLTNLALALRAEPALPRLLRRLVIMGGMFDGQ----PITEWNIRVDPEAASEVFTAWAG 179 GPLTNLALALR EP LPRLL+ L +MGG + + P +EWNI VDPEAA EVF AW Sbjct 136 GPLTNLALALREEPELPRLLKELHVMGGAINYRGNTGPTSEWNIAVDPEAAHEVFEAWGK 195 Query 180 QRQLPIVCGLDLTRRVAMTPDILARLASVCGSSPVMRVIEDALRFYFESHEARGHGYLAY 239 + ++ L T + + R GS PV+RV+ DAL+FYFE H+A G G+ AY Sbjct 196 ASRRVVLGALQATEVIRFDEED-RRAIEGLGSHPVVRVLADALKFYFEFHQADGLGWCAY 254 Query 240 MHDPLAAAVAMDPELLTTRTATVDVD-----PTGATVTDWSGK--RNPNARIGMSVDPAV 292 +HDPL A A+ + +TR VDV+ G TV D G+ + PN + VD Sbjct 255 LHDPLVVANAVTGKFASTRPLAVDVELAGTLTRGQTVGDELGRWGKKPNVDLLCDVDARG 314 Query 293 FFDRFV 298 F + + Sbjct 315 FIEHLM 320 >gi|313836321|gb|EFS74035.1| inosine-uridine preferring nucleoside hydrolase [Propionibacterium acnes HL037PA2] gi|314928785|gb|EFS92616.1| inosine-uridine preferring nucleoside hydrolase [Propionibacterium acnes HL044PA1] gi|314971179|gb|EFT15277.1| inosine-uridine preferring nucleoside hydrolase [Propionibacterium acnes HL037PA3] Length=321 Score = 219 bits (559), Expect = 4e-55, Method: Compositional matrix adjust. Identities = 130/306 (43%), Positives = 172/306 (57%), Gaps = 13/306 (4%) Query 4 VFADVDTGIDDALAVIYLLASPDADLVGIASTGGNIAVGQVCANNLSLLELCGAADIPVS 63 V D D GIDDA A+ YL D + VG+ +T GN+ V N L L EL G D+PV+ Sbjct 10 VLLDCDPGIDDAFALAYLACRHDVETVGVVTTAGNVGQDDVLRNALGLTELLGM-DVPVA 68 Query 64 KGADEPLGGRWPDHPKFHGPKGIGYAELPASNRRLTDYDATTAWIAAAHSHAGDLIGLVT 123 +GAD PL + HGP G+G+A+L RR W+ AH +AG+L+G+ T Sbjct 69 RGADVPLVEPMMTAEETHGPHGLGHAQLGECGRRSDVRSGAQLWVDLAHRYAGELVGITT 128 Query 124 GPLTNLALALRAEPALPRLLRRLVIMGGMFDGQ----PITEWNIRVDPEAASEVFTAWAG 179 GPLTNLALALR EP LPRLL+ L +MGG + + P +EWNI VDPEAA EVF AW Sbjct 129 GPLTNLALALREEPELPRLLKELHVMGGAINYRGNTGPTSEWNIAVDPEAAHEVFEAWGK 188 Query 180 QRQLPIVCGLDLTRRVAMTPDILARLASVCGSSPVMRVIEDALRFYFESHEARGHGYLAY 239 + ++ L T + + R GS PV+RV+ DAL+FYFE H+A G G+ AY Sbjct 189 ASRRVVLGALQATEVIRFDEED-RRAIEGLGSHPVVRVLADALKFYFEFHQADGLGWCAY 247 Query 240 MHDPLAAAVAMDPELLTTRTATVDVD-----PTGATVTDWSGK--RNPNARIGMSVDPAV 292 +HDPL A A+ + +TR VDV+ G TV D G+ + PN + VD Sbjct 248 LHDPLVVANAVTGKFASTRPLAVDVELAGTLTRGQTVGDELGRWGKKPNVDLLCDVDARG 307 Query 293 FFDRFV 298 F + + Sbjct 308 FIEHLM 313 >gi|220912409|ref|YP_002487718.1| inosine/uridine-specific nucleoside hydrolase [Arthrobacter chlorophenolicus A6] gi|219859287|gb|ACL39629.1| Inosine/uridine-preferring nucleoside hydrolase [Arthrobacter chlorophenolicus A6] Length=341 Score = 217 bits (553), Expect = 2e-54, Method: Compositional matrix adjust. Identities = 141/339 (42%), Positives = 181/339 (54%), Gaps = 32/339 (9%) Query 1 VSVVFADVDTGIDDALAVIYLLASPDADLVGIASTGGNIAVGQVCANNLSLLELCGAADI 60 ++ DVDTGIDDALA+ YL A PD + V + +T GN+ QV N L+LLELCG + Sbjct 1 MTAFLLDVDTGIDDALALAYLAALPDTEFVSVTATPGNVDADQVAQNTLALLELCGRRGV 60 Query 61 PVSKGADEPLGGRWPDHPKFHGPKGIGYAELPASNRRLTDYDATTAWIAAAHSHAGDLIG 120 V+ GA PL P+ HGP+GIGYA LP + +++ +A WI A + G+L Sbjct 61 EVAIGARAPLSVPLVTTPETHGPQGIGYAVLPEPDGQVSARNAVDLWIDHARARPGELTA 120 Query 121 LVTGPLTNLALALRAEPALPRLLRRLVIMGGMFDGQ----PITEWNIRVDPEAASEV--F 174 L+T PLTN ALALR EP LP LL +VIMGG F Q P EWN VDP AA EV Sbjct 121 LITAPLTNFALALRKEPELPELLAGVVIMGGSFYHQGNTTPTAEWNTHVDPHAAKEVYAA 180 Query 175 TAWAGQRQLPIVCGLDLTRRVAMTPDILARLASVCGSS-------------------PVM 215 +LP+VC LD T R+ + P+ + LA G+S V+ Sbjct 181 YRGRAAAKLPVVCSLDTTERMELRPEHVRLLAEAAGASVPELVLPDQPEGRRSTSDNRVI 240 Query 216 RVIEDALRFYFESHEARGHGYLAYMHDPLAAAVAMDPELLTTRTATVDVDP-----TGAT 270 R + DALRFYFE H GYLA++HD AA VA + R AT+D++ TG T Sbjct 241 RHLSDALRFYFEFHRLYDQGYLAHVHDFFAAGVAAGTLEYSARPATIDIETDSPLLTGTT 300 Query 271 VTDWSG--KRNPNARIGMSVDPAVFFDRFVERIGRFARR 307 V D+ G PNARI + +P F +G A R Sbjct 301 VADYRGLWGSAPNARIVSANNPEQAFRELTAAVGSLAAR 339 >gi|340770089|gb|EGR92605.1| inosine-uridine preferring nucleoside hydrolase [Propionibacterium acnes SK182B-JCVI] Length=321 Score = 214 bits (545), Expect = 1e-53, Method: Compositional matrix adjust. Identities = 127/306 (42%), Positives = 171/306 (56%), Gaps = 13/306 (4%) Query 4 VFADVDTGIDDALAVIYLLASPDADLVGIASTGGNIAVGQVCANNLSLLELCGAADIPVS 63 V D D GIDDA A+ YL D + VG+ +T GN+ V N L L +L G D PV+ Sbjct 10 VLLDCDPGIDDAFALAYLACRDDVETVGVVTTAGNVGQDDVLRNALGLTDLLGM-DAPVA 68 Query 64 KGADEPLGGRWPDHPKFHGPKGIGYAELPASNRRLTDYDATTAWIAAAHSHAGDLIGLVT 123 +GAD PL + + HGP G+G+A L RR W+ AH + G+L+G+VT Sbjct 69 RGADVPLAEPFKTAEETHGPHGLGHAVLGECGRRPDSRSGAQLWVDLAHRYPGELVGIVT 128 Query 124 GPLTNLALALRAEPALPRLLRRLVIMGGMFDGQ----PITEWNIRVDPEAASEVFTAWAG 179 GPLTNLALALR EP LPRLLR L +MGG + + P +EWNI VDPEA EVF AW Sbjct 129 GPLTNLALALREEPELPRLLRGLHVMGGAINHRGNTGPTSEWNIAVDPEAGHEVFEAWGK 188 Query 180 QRQLPIVCGLDLTRRVAMTPDILARLASVCGSSPVMRVIEDALRFYFESHEARGHGYLAY 239 + ++ L T + + + L + ++ G PV+ V+ DALRFYF+ H+A G G+ AY Sbjct 189 ASRRVVLGALQATEVIRLDDEHLHAVENL-GDHPVIAVLSDALRFYFQFHQADGLGWCAY 247 Query 240 MHDPLAAAVAMDPELLTTRTATVDVD-----PTGATVTDWSGK--RNPNARIGMSVDPAV 292 +HDPL A A+ +TR VDV+ G TV D G+ + PN + VD Sbjct 248 LHDPLVVANAVTGRFASTRPLAVDVELAGTLTRGQTVGDELGRWGKEPNVDLLCDVDAEG 307 Query 293 FFDRFV 298 F + + Sbjct 308 FIEHLL 313 >gi|313763714|gb|EFS35078.1| inosine-uridine preferring nucleoside hydrolase [Propionibacterium acnes HL013PA1] gi|314918811|gb|EFS82642.1| inosine-uridine preferring nucleoside hydrolase [Propionibacterium acnes HL050PA1] gi|314921016|gb|EFS84847.1| inosine-uridine preferring nucleoside hydrolase [Propionibacterium acnes HL050PA3] gi|327455835|gb|EGF02490.1| inosine-uridine preferring nucleoside hydrolase [Propionibacterium acnes HL087PA3] gi|328757150|gb|EGF70766.1| inosine-uridine preferring nucleoside hydrolase [Propionibacterium acnes HL087PA1] Length=449 Score = 213 bits (542), Expect = 3e-53, Method: Compositional matrix adjust. Identities = 131/306 (43%), Positives = 168/306 (55%), Gaps = 13/306 (4%) Query 4 VFADVDTGIDDALAVIYLLASPDADLVGIASTGGNIAVGQVCANNLSLLELCGAADIPVS 63 V D D GIDDA A+ YL + D + VG+ +T GN+ V N L L EL G D PV+ Sbjct 138 VLLDCDPGIDDAFALAYLASRDDVETVGVVTTAGNVGQDDVLRNALGLTELLGM-DAPVA 196 Query 64 KGADEPLGGRWPDHPKFHGPKGIGYAELPASNRRLTDYDATTAWIAAAHSHAGDLIGLVT 123 +GAD PL + HGP G+G+A+L R W+ A + G+L+G+VT Sbjct 197 RGADAPLVEPVMTAEETHGPHGLGHAQLGDCGRHPDGRSGAQLWVDLARKYPGELVGIVT 256 Query 124 GPLTNLALALRAEPALPRLLRRLVIMGGMFDGQ----PITEWNIRVDPEAASEVFTAWAG 179 GPLTNLALALR EP LP+LLR L +MGG + + P +EWNI VDPEA EVF AW G Sbjct 257 GPLTNLALALREEPDLPQLLRGLHVMGGAINHRGNTGPTSEWNIAVDPEAGHEVFEAW-G 315 Query 180 QRQLPIVCGLDLTRRVAMTPDILARLASVCGSSPVMRVIEDALRFYFESHEARGHGYLAY 239 + +V G V + R G PV++V+ DALRFYFE HEA G G+ AY Sbjct 316 KASKRVVLGALQATEVIRLDERDRRAVKELGEHPVVKVLADALRFYFEFHEADGLGWCAY 375 Query 240 MHDPLAAAVAMDPELLTTRTATVDVDPTGA-----TVTDWSGK--RNPNARIGMSVDPAV 292 +HDPL A A+ TTR VDV+ TG TV D G+ + PN + VD Sbjct 376 LHDPLVVANAVTGRFATTRPLAVDVELTGTLTRGQTVGDELGRWGKEPNVDLLCEVDAEG 435 Query 293 FFDRFV 298 F + + Sbjct 436 FIEHLL 441 >gi|319949206|ref|ZP_08023293.1| inosine/uridine-preferring nucleoside hydrolase [Dietzia cinnamea P4] gi|319437120|gb|EFV92153.1| inosine/uridine-preferring nucleoside hydrolase [Dietzia cinnamea P4] Length=335 Score = 213 bits (542), Expect = 3e-53, Method: Compositional matrix adjust. Identities = 129/302 (43%), Positives = 172/302 (57%), Gaps = 22/302 (7%) Query 4 VFADVDTGIDDALAVIYLLASPDA---DLVGIASTGGNIAVGQVCANNLSLLELCGAADI 60 V D D GIDDALA+ YL+A A DL G+ T GN+ + AN L+ L+L GA + Sbjct 6 VLLDCDPGIDDALAIAYLVAEYRAGRIDLAGLVCTAGNVGLDDTVANALAWLDLAGAPPV 65 Query 61 PVSKGADEPLGGRWPDHPKFHGPKGIGYAELPASNRRLTDYDATTAWIAAAHSHAGDLIG 120 PV+ GA P+ P+ HGP+G G+AEL + R L D W+ A +H G+L+G Sbjct 66 PVAAGAPRPIAVPHVLTPETHGPRGAGHAELTTTTRALDPRDGARLWVELARAHPGELVG 125 Query 121 LVTGPLTNLALALRAEPALPRLLRRLVIMGGMFDGQ-----PITEWNIRVDPEAASEVFT 175 +VTGP ++LA A+ +PALP LL RLV+MGG F G P++EWN+ VDPEAA + Sbjct 126 IVTGPSSSLARAVALDPALPGLLARLVVMGGTFRGHPGNTTPVSEWNVDVDPEAADRICR 185 Query 176 AWAGQR------QLPIVCGLDLTRRVAMTPDILARLASVCGSSPVMRVIEDALRFYFESH 229 W R P+ CGL+LT R TP+ +R +P+ R + DALRFYFE H Sbjct 186 VWENARAADPAVTAPLWCGLNLTERAVWTPE-RSRELLAAADTPLTRALVDALRFYFEFH 244 Query 230 EARGHGYLAYMHDPLAAAVAMDPELLTTRTATVDVDPTGA-----TVTDWSGKRN--PNA 282 E+ G GYLA +HDPL A +A+ P + A V V+ G TV D G+R NA Sbjct 245 ESVGEGYLAQVHDPLVAWLALHPGSEVSEPAHVRVECAGEHTRGMTVADVRGQRGRVDNA 304 Query 283 RI 284 R+ Sbjct 305 RV 306 >gi|289426046|ref|ZP_06427793.1| inosine-uridine preferring nucleoside hydrolase [Propionibacterium acnes SK187] gi|289427994|ref|ZP_06429698.1| inosine-uridine preferring nucleoside hydrolase [Propionibacterium acnes J165] gi|295131587|ref|YP_003582250.1| inosine-uridine preferring nucleoside hydrolase [Propionibacterium acnes SK137] gi|289153589|gb|EFD02303.1| inosine-uridine preferring nucleoside hydrolase [Propionibacterium acnes SK187] gi|289158877|gb|EFD07077.1| inosine-uridine preferring nucleoside hydrolase [Propionibacterium acnes J165] gi|291375312|gb|ADD99166.1| inosine-uridine preferring nucleoside hydrolase [Propionibacterium acnes SK137] gi|340773974|gb|EGR96464.1| inosine-uridine preferring nucleoside hydrolase [Propionibacterium acnes SK182] Length=356 Score = 213 bits (542), Expect = 3e-53, Method: Compositional matrix adjust. Identities = 131/306 (43%), Positives = 168/306 (55%), Gaps = 13/306 (4%) Query 4 VFADVDTGIDDALAVIYLLASPDADLVGIASTGGNIAVGQVCANNLSLLELCGAADIPVS 63 V D D GIDDA A+ YL + D + VG+ +T GN+ V N L L EL G D PV+ Sbjct 45 VLLDCDPGIDDAFALAYLASRDDVETVGVVTTAGNVGQDDVLRNALGLTELLGM-DAPVA 103 Query 64 KGADEPLGGRWPDHPKFHGPKGIGYAELPASNRRLTDYDATTAWIAAAHSHAGDLIGLVT 123 +GAD PL + HGP G+G+A+L R W+ A + G+L+G+VT Sbjct 104 RGADAPLVEPVMTAEETHGPHGLGHAQLGDCGRHPDGRSGAQLWVDLARKYPGELVGIVT 163 Query 124 GPLTNLALALRAEPALPRLLRRLVIMGGMFDGQ----PITEWNIRVDPEAASEVFTAWAG 179 GPLTNLALALR EP LP+LLR L +MGG + + P +EWNI VDPEA EVF AW G Sbjct 164 GPLTNLALALREEPDLPQLLRGLHVMGGAINHRGNTGPTSEWNIAVDPEAGHEVFEAW-G 222 Query 180 QRQLPIVCGLDLTRRVAMTPDILARLASVCGSSPVMRVIEDALRFYFESHEARGHGYLAY 239 + +V G V + R G PV++V+ DALRFYFE HEA G G+ AY Sbjct 223 KASKRVVLGALQATEVIRLDERDRRAVKELGEHPVVKVLADALRFYFEFHEADGLGWCAY 282 Query 240 MHDPLAAAVAMDPELLTTRTATVDVDPTGA-----TVTDWSGK--RNPNARIGMSVDPAV 292 +HDPL A A+ TTR VDV+ TG TV D G+ + PN + VD Sbjct 283 LHDPLVVANAVTGRFATTRPLAVDVELTGTLTRGQTVGDELGRWGKEPNVDLLCEVDAEG 342 Query 293 FFDRFV 298 F + + Sbjct 343 FIEHLL 348 >gi|313771731|gb|EFS37697.1| inosine-uridine preferring nucleoside hydrolase [Propionibacterium acnes HL074PA1] gi|313793740|gb|EFS41771.1| inosine-uridine preferring nucleoside hydrolase [Propionibacterium acnes HL110PA1] gi|313803052|gb|EFS44260.1| inosine-uridine preferring nucleoside hydrolase [Propionibacterium acnes HL110PA2] 41 more sequence titles Length=449 Score = 213 bits (541), Expect = 4e-53, Method: Compositional matrix adjust. Identities = 131/306 (43%), Positives = 168/306 (55%), Gaps = 13/306 (4%) Query 4 VFADVDTGIDDALAVIYLLASPDADLVGIASTGGNIAVGQVCANNLSLLELCGAADIPVS 63 V D D GIDDA A+ YL + D + VG+ +T GN+ V N L L EL G D PV+ Sbjct 138 VLLDCDPGIDDAFALAYLASRDDVETVGVVTTAGNVGQDDVLRNALGLTELLGM-DAPVA 196 Query 64 KGADEPLGGRWPDHPKFHGPKGIGYAELPASNRRLTDYDATTAWIAAAHSHAGDLIGLVT 123 +GAD PL + HGP G+G+A+L R W+ A + G+L+G+VT Sbjct 197 RGADAPLVEPVMTAEETHGPHGLGHAQLGDCGRHPDGRSGAQLWVDLARKYPGELVGIVT 256 Query 124 GPLTNLALALRAEPALPRLLRRLVIMGGMFDGQ----PITEWNIRVDPEAASEVFTAWAG 179 GPLTNLALALR EP LP+LLR L +MGG + + P +EWNI VDPEA EVF AW G Sbjct 257 GPLTNLALALREEPDLPQLLRGLHVMGGAINHRGNTGPTSEWNIAVDPEAGHEVFEAW-G 315 Query 180 QRQLPIVCGLDLTRRVAMTPDILARLASVCGSSPVMRVIEDALRFYFESHEARGHGYLAY 239 + +V G V + R G PV++V+ DALRFYFE HEA G G+ AY Sbjct 316 KASKRVVLGALQATEVIRLDERDRRAVKELGEHPVVKVLADALRFYFEFHEADGLGWCAY 375 Query 240 MHDPLAAAVAMDPELLTTRTATVDVDPTGA-----TVTDWSGK--RNPNARIGMSVDPAV 292 +HDPL A A+ TTR VDV+ TG TV D G+ + PN + VD Sbjct 376 LHDPLVVANAVTGRFATTRPLAVDVELTGTLTRGQTVGDELGRWGKEPNVDLLCEVDAEG 435 Query 293 FFDRFV 298 F + + Sbjct 436 FIEHLL 441 >gi|313810553|gb|EFS48267.1| inosine-uridine preferring nucleoside hydrolase [Propionibacterium acnes HL083PA1] Length=372 Score = 213 bits (541), Expect = 4e-53, Method: Compositional matrix adjust. Identities = 131/306 (43%), Positives = 168/306 (55%), Gaps = 13/306 (4%) Query 4 VFADVDTGIDDALAVIYLLASPDADLVGIASTGGNIAVGQVCANNLSLLELCGAADIPVS 63 V D D GIDDA A+ YL + D + VG+ +T GN+ V N L L EL G D PV+ Sbjct 61 VLLDCDPGIDDAFALAYLASRDDVETVGVVTTAGNVGQDDVLRNALGLTELLGM-DAPVA 119 Query 64 KGADEPLGGRWPDHPKFHGPKGIGYAELPASNRRLTDYDATTAWIAAAHSHAGDLIGLVT 123 +GAD PL + HGP G+G+A+L R W+ A + G+L+G+VT Sbjct 120 RGADAPLVEPVMTAEETHGPHGLGHAQLGDCGRHPDGRSGAQLWVDLARKYPGELVGIVT 179 Query 124 GPLTNLALALRAEPALPRLLRRLVIMGGMFDGQ----PITEWNIRVDPEAASEVFTAWAG 179 GPLTNLALALR EP LP+LLR L +MGG + + P +EWNI VDPEA EVF AW G Sbjct 180 GPLTNLALALREEPDLPQLLRGLHVMGGAINHRGNTGPTSEWNIAVDPEAGHEVFEAW-G 238 Query 180 QRQLPIVCGLDLTRRVAMTPDILARLASVCGSSPVMRVIEDALRFYFESHEARGHGYLAY 239 + +V G V + R G PV++V+ DALRFYFE HEA G G+ AY Sbjct 239 KASKRVVLGALQATEVIRLDERDRRAVKELGEHPVVKVLADALRFYFEFHEADGLGWCAY 298 Query 240 MHDPLAAAVAMDPELLTTRTATVDVDPTGA-----TVTDWSGK--RNPNARIGMSVDPAV 292 +HDPL A A+ TTR VDV+ TG TV D G+ + PN + VD Sbjct 299 LHDPLVVANAVTGRFATTRPLAVDVELTGTLTRGQTVGDELGRWGKEPNVDLLCEVDAEG 358 Query 293 FFDRFV 298 F + + Sbjct 359 FIEHLL 364 >gi|314984630|gb|EFT28722.1| inosine-uridine preferring nucleoside hydrolase [Propionibacterium acnes HL005PA1] Length=449 Score = 213 bits (541), Expect = 4e-53, Method: Compositional matrix adjust. Identities = 131/306 (43%), Positives = 168/306 (55%), Gaps = 13/306 (4%) Query 4 VFADVDTGIDDALAVIYLLASPDADLVGIASTGGNIAVGQVCANNLSLLELCGAADIPVS 63 V D D GIDDA A+ YL + D + VG+ +T GN+ V N L L EL G D PV+ Sbjct 138 VLLDCDPGIDDAFALAYLASRDDVETVGVVTTAGNVGQDDVLRNALGLTELLGM-DAPVA 196 Query 64 KGADEPLGGRWPDHPKFHGPKGIGYAELPASNRRLTDYDATTAWIAAAHSHAGDLIGLVT 123 +GAD PL + HGP G+G+A+L R W+ A + G+L+G+VT Sbjct 197 RGADAPLVEPVMTAEETHGPHGLGHAQLGDCGRHPDGRSGAQLWVDLARKYPGELVGIVT 256 Query 124 GPLTNLALALRAEPALPRLLRRLVIMGGMFDGQ----PITEWNIRVDPEAASEVFTAWAG 179 GPLTNLALALR EP LP+LLR L +MGG + + P +EWNI VDPEA EVF AW G Sbjct 257 GPLTNLALALREEPDLPQLLRGLHVMGGAINHRGNTGPTSEWNIAVDPEAGHEVFEAW-G 315 Query 180 QRQLPIVCGLDLTRRVAMTPDILARLASVCGSSPVMRVIEDALRFYFESHEARGHGYLAY 239 + +V G V + R G PV++V+ DALRFYFE HEA G G+ AY Sbjct 316 KASKRVVLGALQATEVIRLDERDRRAVKELGEHPVVKVLADALRFYFEFHEADGLGWCAY 375 Query 240 MHDPLAAAVAMDPELLTTRTATVDVDPTGA-----TVTDWSGK--RNPNARIGMSVDPAV 292 +HDPL A A+ TTR VDV+ TG TV D G+ + PN + VD Sbjct 376 LHDPLVVANAVTGRFATTRPLAVDVELTGTLTRGQTVGDELGRWGKEPNVDLLCEVDAEG 435 Query 293 FFDRFV 298 F + + Sbjct 436 FIEHLL 441 Lambda K H 0.321 0.138 0.422 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 524399257434 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40