BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv3405c Length=188 Score E Sequences producing significant alignments: (Bits) Value gi|15610541|ref|NP_217922.1| transcriptional regulatory protein ... 372 9e-102 gi|306799381|ref|ZP_07437683.1| transcriptional regulator [Mycob... 369 1e-100 gi|308232453|ref|ZP_07416082.2| transcriptional regulator [Mycob... 350 5e-95 gi|342861603|ref|ZP_08718250.1| transcriptional regulator [Mycob... 275 2e-72 gi|336459708|gb|EGO38633.1| transcriptional regulator [Mycobacte... 267 6e-70 gi|254821007|ref|ZP_05226008.1| putative HTH-type transcriptiona... 265 2e-69 gi|254776781|ref|ZP_05218297.1| putative HTH-type transcriptiona... 265 2e-69 gi|296168789|ref|ZP_06850474.1| TetR family transcriptional regu... 261 3e-68 gi|118464489|ref|YP_883487.1| HTH-type transcriptional regulator... 243 9e-63 gi|118616673|ref|YP_905005.1| transcriptional regulator [Mycobac... 239 1e-61 gi|183981163|ref|YP_001849454.1| transcriptional regulator [Myco... 231 3e-59 gi|240167844|ref|ZP_04746503.1| transcriptional regulator [Mycob... 228 2e-58 gi|341603351|emb|CCC66032.1| BCGM3439c [Mycobacterium bovis BCG ... 197 4e-49 gi|317507389|ref|ZP_07965124.1| tetR family bacterial regulatory... 159 2e-37 gi|169627190|ref|YP_001700839.1| putative transcriptional regula... 158 5e-37 gi|126433594|ref|YP_001069285.1| TetR family transcriptional reg... 155 3e-36 gi|118469617|ref|YP_884596.1| HTH-type transcriptional regulator... 150 7e-35 gi|218780279|ref|YP_002431597.1| TetR family transcriptional reg... 95.1 4e-18 gi|218783005|ref|YP_002434323.1| TetR family transcriptional reg... 90.5 1e-16 gi|311744261|ref|ZP_07718065.1| TetR family transcriptional regu... 80.1 1e-13 gi|326382361|ref|ZP_08204053.1| transcriptional regulator [Gordo... 73.9 1e-11 gi|312197983|ref|YP_004018044.1| TetR family transcriptional reg... 68.9 3e-10 gi|302547787|ref|ZP_07300129.1| putative TetR-family transcripti... 67.4 9e-10 gi|288916092|ref|ZP_06410473.1| transcriptional regulator, TetR ... 65.9 3e-09 gi|226525269|gb|ACO70869.1| transcriptional regulator TetR famil... 60.8 9e-08 gi|297162534|gb|ADI12246.1| TetR family transcriptional regulato... 60.5 1e-07 gi|228991428|ref|ZP_04151383.1| Transcriptional regulator, TetR ... 59.3 3e-07 gi|228997532|ref|ZP_04157147.1| Transcriptional regulator, TetR ... 59.3 3e-07 gi|296120826|ref|YP_003628604.1| regulatory protein TetR [Planct... 59.3 3e-07 gi|229085423|ref|ZP_04217664.1| Transcriptional regulator, TetR ... 59.3 3e-07 gi|134098011|ref|YP_001103672.1| TetR family transcriptional reg... 58.5 5e-07 gi|319948030|ref|ZP_08022206.1| transcriptional regulator [Dietz... 58.2 6e-07 gi|300785854|ref|YP_003766145.1| TetR family transcriptional reg... 58.2 7e-07 gi|337769606|emb|CCB78319.1| Transcriptional regulator, TetR fam... 57.8 8e-07 gi|149188374|ref|ZP_01866668.1| transcriptional regulator, TetR ... 57.8 8e-07 gi|322436748|ref|YP_004218960.1| regulatory protein TetR [Acidob... 57.4 9e-07 gi|308049886|ref|YP_003913452.1| TetR family transcriptional reg... 57.4 9e-07 gi|89895559|ref|YP_519046.1| hypothetical protein DSY2813 [Desul... 57.4 1e-06 gi|256822023|ref|YP_003145986.1| TetR family transcriptional reg... 57.0 1e-06 gi|345001669|ref|YP_004804523.1| TetR family transcriptional reg... 56.2 2e-06 gi|149923989|ref|ZP_01912374.1| probable transcriptional regulat... 56.2 2e-06 gi|114798426|ref|YP_761142.1| TetR family transcriptional regula... 56.2 2e-06 gi|91776914|ref|YP_546670.1| TetR family transcriptional regulat... 56.2 2e-06 gi|337746706|ref|YP_004640868.1| TetR family transcriptional reg... 56.2 2e-06 gi|345012662|ref|YP_004815016.1| regulatory protein TetR [Strept... 56.2 2e-06 gi|111219807|ref|YP_710601.1| TetR family transcriptional regula... 56.2 2e-06 gi|158313472|ref|YP_001505980.1| TetR family transcriptional reg... 56.2 2e-06 gi|117164538|emb|CAJ88084.1| putative TetR-family transcriptiona... 55.8 3e-06 gi|111222936|ref|YP_713730.1| putative HTH-type transcriptional ... 55.5 4e-06 gi|300784384|ref|YP_003764675.1| TetR family transcriptional reg... 55.5 4e-06 >gi|15610541|ref|NP_217922.1| transcriptional regulatory protein [Mycobacterium tuberculosis H37Rv] gi|15843000|ref|NP_338037.1| TetR family transcriptional regulator [Mycobacterium tuberculosis CDC1551] gi|31794586|ref|NP_857079.1| transcriptional regulatory protein [Mycobacterium bovis AF2122/97] 65 more sequence titles Length=188 Score = 372 bits (956), Expect = 9e-102, Method: Compositional matrix adjust. Identities = 188/188 (100%), Positives = 188/188 (100%), Gaps = 0/188 (0%) Query 1 MTTRPATDRRKMPTGREEVAAAILQAATDLFAERGPAATSIRDIAARSKVNHGLVFRHFG 60 MTTRPATDRRKMPTGREEVAAAILQAATDLFAERGPAATSIRDIAARSKVNHGLVFRHFG Sbjct 1 MTTRPATDRRKMPTGREEVAAAILQAATDLFAERGPAATSIRDIAARSKVNHGLVFRHFG 60 Query 61 TKDQLVGAVLDHLGTKLTRLLHSEAPADIIERALDRHGRVLARALLDGYPVGQLQQRFPN 120 TKDQLVGAVLDHLGTKLTRLLHSEAPADIIERALDRHGRVLARALLDGYPVGQLQQRFPN Sbjct 61 TKDQLVGAVLDHLGTKLTRLLHSEAPADIIERALDRHGRVLARALLDGYPVGQLQQRFPN 120 Query 121 VAELLDAVRPRYDSDLGARLAVAHALALQFGWRLFAPMLRSATGIDELTGDELRLSVNDA 180 VAELLDAVRPRYDSDLGARLAVAHALALQFGWRLFAPMLRSATGIDELTGDELRLSVNDA Sbjct 121 VAELLDAVRPRYDSDLGARLAVAHALALQFGWRLFAPMLRSATGIDELTGDELRLSVNDA 180 Query 181 VARILEPH 188 VARILEPH Sbjct 181 VARILEPH 188 >gi|306799381|ref|ZP_07437683.1| transcriptional regulator [Mycobacterium tuberculosis SUMu006] gi|308340395|gb|EFP29246.1| transcriptional regulator [Mycobacterium tuberculosis SUMu006] Length=188 Score = 369 bits (948), Expect = 1e-100, Method: Compositional matrix adjust. Identities = 187/188 (99%), Positives = 187/188 (99%), Gaps = 0/188 (0%) Query 1 MTTRPATDRRKMPTGREEVAAAILQAATDLFAERGPAATSIRDIAARSKVNHGLVFRHFG 60 MTTRPATDRRKMPTGREEVAAAILQAATDLFAERGPAATSIRDIAARSKVNHGLVFRHFG Sbjct 1 MTTRPATDRRKMPTGREEVAAAILQAATDLFAERGPAATSIRDIAARSKVNHGLVFRHFG 60 Query 61 TKDQLVGAVLDHLGTKLTRLLHSEAPADIIERALDRHGRVLARALLDGYPVGQLQQRFPN 120 TKDQLVGAVLDHLGTKLTRLLHSEAPADIIERALDRHGRVLARALLDGYPVGQLQQRFPN Sbjct 61 TKDQLVGAVLDHLGTKLTRLLHSEAPADIIERALDRHGRVLARALLDGYPVGQLQQRFPN 120 Query 121 VAELLDAVRPRYDSDLGARLAVAHALALQFGWRLFAPMLRSATGIDELTGDELRLSVNDA 180 VAELLDAVRPRYDSDLGARLAVAHALALQFGWRLFAPMLRSATGIDELTGD LRLSVNDA Sbjct 121 VAELLDAVRPRYDSDLGARLAVAHALALQFGWRLFAPMLRSATGIDELTGDGLRLSVNDA 180 Query 181 VARILEPH 188 VARILEPH Sbjct 181 VARILEPH 188 >gi|308232453|ref|ZP_07416082.2| transcriptional regulator [Mycobacterium tuberculosis SUMu001] gi|308370255|ref|ZP_07420810.2| transcriptional regulator [Mycobacterium tuberculosis SUMu002] gi|308372534|ref|ZP_07428985.2| transcriptional regulator [Mycobacterium tuberculosis SUMu004] 9 more sequence titles Length=177 Score = 350 bits (899), Expect = 5e-95, Method: Compositional matrix adjust. Identities = 177/177 (100%), Positives = 177/177 (100%), Gaps = 0/177 (0%) Query 12 MPTGREEVAAAILQAATDLFAERGPAATSIRDIAARSKVNHGLVFRHFGTKDQLVGAVLD 71 MPTGREEVAAAILQAATDLFAERGPAATSIRDIAARSKVNHGLVFRHFGTKDQLVGAVLD Sbjct 1 MPTGREEVAAAILQAATDLFAERGPAATSIRDIAARSKVNHGLVFRHFGTKDQLVGAVLD 60 Query 72 HLGTKLTRLLHSEAPADIIERALDRHGRVLARALLDGYPVGQLQQRFPNVAELLDAVRPR 131 HLGTKLTRLLHSEAPADIIERALDRHGRVLARALLDGYPVGQLQQRFPNVAELLDAVRPR Sbjct 61 HLGTKLTRLLHSEAPADIIERALDRHGRVLARALLDGYPVGQLQQRFPNVAELLDAVRPR 120 Query 132 YDSDLGARLAVAHALALQFGWRLFAPMLRSATGIDELTGDELRLSVNDAVARILEPH 188 YDSDLGARLAVAHALALQFGWRLFAPMLRSATGIDELTGDELRLSVNDAVARILEPH Sbjct 121 YDSDLGARLAVAHALALQFGWRLFAPMLRSATGIDELTGDELRLSVNDAVARILEPH 177 >gi|342861603|ref|ZP_08718250.1| transcriptional regulator [Mycobacterium colombiense CECT 3035] gi|342131092|gb|EGT84381.1| transcriptional regulator [Mycobacterium colombiense CECT 3035] Length=191 Score = 275 bits (703), Expect = 2e-72, Method: Compositional matrix adjust. Identities = 137/187 (74%), Positives = 158/187 (85%), Gaps = 0/187 (0%) Query 1 MTTRPATDRRKMPTGREEVAAAILQAATDLFAERGPAATSIRDIAARSKVNHGLVFRHFG 60 MTT AT R KMPTGR EVAAAIL+AATDLFAERGPAATSIRDIAARS VNHGLVFRHFG Sbjct 1 MTTTSATGRGKMPTGRAEVAAAILEAATDLFAERGPAATSIRDIAARSNVNHGLVFRHFG 60 Query 61 TKDQLVGAVLDHLGTKLTRLLHSEAPADIIERALDRHGRVLARALLDGYPVGQLQQRFPN 120 TK+QLVGAVLDHLG L+ LL ++APA +++ +LDR RV+AR +LDGYP GQLQ+RFPN Sbjct 61 TKEQLVGAVLDHLGANLSALLGTDAPAAVLQSSLDRQMRVMARTVLDGYPAGQLQKRFPN 120 Query 121 VAELLDAVRPRYDSDLGARLAVAHALALQFGWRLFAPMLRSATGIDELTGDELRLSVNDA 180 +A LLD VRP YD ++ ARLAVA+ALALQFGWRLFAP+LRSATGI++LT DE+R + Sbjct 121 IATLLDGVRPLYDDEVKARLAVANALALQFGWRLFAPILRSATGIEDLTDDEIREAAGAE 180 Query 181 VARILEP 187 V RIL P Sbjct 181 VQRILGP 187 >gi|336459708|gb|EGO38633.1| transcriptional regulator [Mycobacterium avium subsp. paratuberculosis S397] Length=191 Score = 267 bits (682), Expect = 6e-70, Method: Compositional matrix adjust. Identities = 137/191 (72%), Positives = 158/191 (83%), Gaps = 3/191 (1%) Query 1 MTTRPATDRRKMPTGREEVAAAILQAATDLFAERGPAATSIRDIAARSKVNHGLVFRHFG 60 MTT AT RRK PTGR EVAAAIL+AATDLFAERGPAATSIRDIAAR VNHGLVFRHFG Sbjct 1 MTTTSATRRRKPPTGRAEVAAAILEAATDLFAERGPAATSIRDIAARCGVNHGLVFRHFG 60 Query 61 TKDQLVGAVLDHLGTKLTRLLHSEAPADIIERALDRHGRVLARALLDGYPVGQLQQRFPN 120 TK+QLVGAVLDHLG L+ LL ++ PA+++E++LDR RV+AR +LDGYP GQLQ+RFPN Sbjct 61 TKEQLVGAVLDHLGANLSALLATDTPAEVVEQSLDRQMRVMARTVLDGYPAGQLQKRFPN 120 Query 121 VAELLDAVRPRYDSDLGARLAVAHALALQFGWRLFAPMLRSATGIDELTGDELRLSVNDA 180 +A LLD VRP +D +L ARLAVA+ALALQFGWRLFAP+LR+ATGI+ELT ELR + Sbjct 121 IATLLDGVRPLHDDELHARLAVANALALQFGWRLFAPILRAATGIEELTDAELRRAAGAE 180 Query 181 VARILE---PH 188 V RIL PH Sbjct 181 VERILRSPGPH 191 >gi|254821007|ref|ZP_05226008.1| putative HTH-type transcriptional regulator [Mycobacterium intracellulare ATCC 13950] Length=191 Score = 265 bits (678), Expect = 2e-69, Method: Compositional matrix adjust. Identities = 133/187 (72%), Positives = 156/187 (84%), Gaps = 0/187 (0%) Query 1 MTTRPATDRRKMPTGREEVAAAILQAATDLFAERGPAATSIRDIAARSKVNHGLVFRHFG 60 MTT A R K PTGR EVAAAIL+AAT+LFAERGPAATSIRDIAAR+ VNHGLVFRHFG Sbjct 1 MTTTSARGRGKPPTGRAEVAAAILEAATELFAERGPAATSIRDIAARAGVNHGLVFRHFG 60 Query 61 TKDQLVGAVLDHLGTKLTRLLHSEAPADIIERALDRHGRVLARALLDGYPVGQLQQRFPN 120 TK+QLVGAVLDHLG L+ L ++ PA++++R+LDR RV+AR +LDGYP GQLQ+RFPN Sbjct 61 TKEQLVGAVLDHLGDDLSAQLETDTPAEVVQRSLDRQMRVMARTVLDGYPAGQLQKRFPN 120 Query 121 VAELLDAVRPRYDSDLGARLAVAHALALQFGWRLFAPMLRSATGIDELTGDELRLSVNDA 180 +A LLD VRP YD ++ ARLAVA+ALALQFGWRLFAP+LRSATGI+ELT ELR +V Sbjct 121 IATLLDGVRPLYDDEVKARLAVANALALQFGWRLFAPVLRSATGIEELTDAELRAAVGAE 180 Query 181 VARILEP 187 V R+L P Sbjct 181 VERMLGP 187 >gi|254776781|ref|ZP_05218297.1| putative HTH-type transcriptional regulator [Mycobacterium avium subsp. avium ATCC 25291] Length=191 Score = 265 bits (677), Expect = 2e-69, Method: Compositional matrix adjust. Identities = 136/191 (72%), Positives = 158/191 (83%), Gaps = 3/191 (1%) Query 1 MTTRPATDRRKMPTGREEVAAAILQAATDLFAERGPAATSIRDIAARSKVNHGLVFRHFG 60 MTT AT RK PTGR EVAAAIL+AATDLFAERGPAATSIRDIAAR VNHGLVFRHFG Sbjct 1 MTTTSATRPRKPPTGRAEVAAAILEAATDLFAERGPAATSIRDIAARCGVNHGLVFRHFG 60 Query 61 TKDQLVGAVLDHLGTKLTRLLHSEAPADIIERALDRHGRVLARALLDGYPVGQLQQRFPN 120 TK+QLVGAVLDHLG L+ LL ++ PA+++E++LDR RV+AR +LDGYP GQLQ+RFPN Sbjct 61 TKEQLVGAVLDHLGANLSALLATDTPAEVVEQSLDRQMRVMARTVLDGYPAGQLQKRFPN 120 Query 121 VAELLDAVRPRYDSDLGARLAVAHALALQFGWRLFAPMLRSATGIDELTGDELRLSVNDA 180 +A LLD VRP +D +L ARLAVA+ALALQFGWRLFAP+LR+ATGI+ELT ELR + Sbjct 121 IATLLDGVRPLHDDELHARLAVANALALQFGWRLFAPILRAATGIEELTDAELRRAAGAE 180 Query 181 VARIL---EPH 188 V RIL +PH Sbjct 181 VERILRSPDPH 191 >gi|296168789|ref|ZP_06850474.1| TetR family transcriptional regulator [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295896523|gb|EFG76169.1| TetR family transcriptional regulator [Mycobacterium parascrofulaceum ATCC BAA-614] Length=177 Score = 261 bits (668), Expect = 3e-68, Method: Compositional matrix adjust. Identities = 130/176 (74%), Positives = 151/176 (86%), Gaps = 0/176 (0%) Query 12 MPTGREEVAAAILQAATDLFAERGPAATSIRDIAARSKVNHGLVFRHFGTKDQLVGAVLD 71 MPTGR EVAAAIL+AATDLFAERGPAATSIRDIAARS VNHGLVFRHFGTKD+LVGAVLD Sbjct 1 MPTGRAEVAAAILEAATDLFAERGPAATSIRDIAARSNVNHGLVFRHFGTKDKLVGAVLD 60 Query 72 HLGTKLTRLLHSEAPADIIERALDRHGRVLARALLDGYPVGQLQQRFPNVAELLDAVRPR 131 HLG L+ L+ SE PAD+++RALDR RV+AR +LDGYP GQLQ RFP +A LLD V P Sbjct 61 HLGADLSALISSEPPADVLDRALDRQMRVMARTVLDGYPAGQLQTRFPTIAALLDWVLPL 120 Query 132 YDSDLGARLAVAHALALQFGWRLFAPMLRSATGIDELTGDELRLSVNDAVARILEP 187 +D+++ ARLAVA+ALALQFGWRLFAP+LR+ATG+DELT D++R + VARIL P Sbjct 121 HDNEIKARLAVANALALQFGWRLFAPILRTATGLDELTDDDIREAARAEVARILNP 176 >gi|118464489|ref|YP_883487.1| HTH-type transcriptional regulator [Mycobacterium avium 104] gi|118165776|gb|ABK66673.1| putative HTH-type transcriptional regulator [Mycobacterium avium 104] Length=173 Score = 243 bits (620), Expect = 9e-63, Method: Compositional matrix adjust. Identities = 123/173 (72%), Positives = 146/173 (85%), Gaps = 3/173 (1%) Query 19 VAAAILQAATDLFAERGPAATSIRDIAARSKVNHGLVFRHFGTKDQLVGAVLDHLGTKLT 78 +AAAIL+AATDLFAERGPAATSIRDIAAR VNHGLVFRHFGTK+QLVGAVLDHLG L+ Sbjct 1 MAAAILEAATDLFAERGPAATSIRDIAARCGVNHGLVFRHFGTKEQLVGAVLDHLGANLS 60 Query 79 RLLHSEAPADIIERALDRHGRVLARALLDGYPVGQLQQRFPNVAELLDAVRPRYDSDLGA 138 LL ++ PA+++E++LDR RV+AR +LDGYP GQLQ+RFPN+A LLD VRP +D +L A Sbjct 61 ALLATDTPAEVVEQSLDRQMRVMARTVLDGYPAGQLQKRFPNIATLLDGVRPLHDDELHA 120 Query 139 RLAVAHALALQFGWRLFAPMLRSATGIDELTGDELRLSVNDAVARIL---EPH 188 RLAVA+ALALQFGWRLFAP+LR+ATGI+ELT ELR + V RIL +PH Sbjct 121 RLAVANALALQFGWRLFAPILRAATGIEELTDAELRRAAGAEVERILRSPDPH 173 >gi|118616673|ref|YP_905005.1| transcriptional regulator [Mycobacterium ulcerans Agy99] gi|118568783|gb|ABL03534.1| transcriptional regulator [Mycobacterium ulcerans Agy99] Length=191 Score = 239 bits (610), Expect = 1e-61, Method: Compositional matrix adjust. Identities = 136/187 (73%), Positives = 149/187 (80%), Gaps = 0/187 (0%) Query 1 MTTRPATDRRKMPTGREEVAAAILQAATDLFAERGPAATSIRDIAARSKVNHGLVFRHFG 60 MTT A RK PTGREEVAAA+L+AA DLFAERGPAATSIRDIAARSKVNHGLVFRHFG Sbjct 1 MTTGSAIRSRKTPTGREEVAAAVLEAAADLFAERGPAATSIRDIAARSKVNHGLVFRHFG 60 Query 61 TKDQLVGAVLDHLGTKLTRLLHSEAPADIIERALDRHGRVLARALLDGYPVGQLQQRFPN 120 K+QLVGAVLD+LGT LT LL + PAD +ERALDR RV AR LLDGYP QLQ RFPN Sbjct 61 AKEQLVGAVLDYLGTHLTELLRAGTPADDLERALDRQMRVWARTLLDGYPAEQLQTRFPN 120 Query 121 VAELLDAVRPRYDSDLGARLAVAHALALQFGWRLFAPMLRSATGIDELTGDELRLSVNDA 180 VAELL VR + D ARLAVA+A+AL GWRLF PMLRSATG+DEL +LR +V D Sbjct 121 VAELLGQVRVHHGDDTTARLAVANAIALCLGWRLFEPMLRSATGLDELADADLRQAVTDE 180 Query 181 VARILEP 187 VARI+EP Sbjct 181 VARIIEP 187 >gi|183981163|ref|YP_001849454.1| transcriptional regulator [Mycobacterium marinum M] gi|183174489|gb|ACC39599.1| transcriptional regulator [Mycobacterium marinum M] Length=169 Score = 231 bits (590), Expect = 3e-59, Method: Compositional matrix adjust. Identities = 120/165 (73%), Positives = 134/165 (82%), Gaps = 0/165 (0%) Query 23 ILQAATDLFAERGPAATSIRDIAARSKVNHGLVFRHFGTKDQLVGAVLDHLGTKLTRLLH 82 +L+AA DLFAERGPAATSIRDIAARSKVNHGLVFRHFG K+QLVGAVLD+LGT LT LL Sbjct 1 MLEAAADLFAERGPAATSIRDIAARSKVNHGLVFRHFGAKEQLVGAVLDYLGTHLTELLR 60 Query 83 SEAPADIIERALDRHGRVLARALLDGYPVGQLQQRFPNVAELLDAVRPRYDSDLGARLAV 142 + PAD +ERALDR RV AR LLDGYP QLQ RFPNVAELL VR + D ARLAV Sbjct 61 AGTPADDLERALDRQMRVWARTLLDGYPAEQLQTRFPNVAELLGQVRVHHGDDTTARLAV 120 Query 143 AHALALQFGWRLFAPMLRSATGIDELTGDELRLSVNDAVARILEP 187 A+A+AL+ GWRLF PMLRSATG+DEL +LR +V D VARI+EP Sbjct 121 ANAIALRLGWRLFEPMLRSATGLDELADADLRQAVTDEVARIIEP 165 >gi|240167844|ref|ZP_04746503.1| transcriptional regulator [Mycobacterium kansasii ATCC 12478] Length=170 Score = 228 bits (582), Expect = 2e-58, Method: Compositional matrix adjust. Identities = 118/160 (74%), Positives = 130/160 (82%), Gaps = 0/160 (0%) Query 29 DLFAERGPAATSIRDIAARSKVNHGLVFRHFGTKDQLVGAVLDHLGTKLTRLLHSEAPAD 88 DLFAERGPAATSIRDIAARS+VNHGLVFRHFGTKDQLVGAVL+HLG KLT LLHS A + Sbjct 11 DLFAERGPAATSIRDIAARSQVNHGLVFRHFGTKDQLVGAVLNHLGAKLTGLLHSGASTE 70 Query 89 IIERALDRHGRVLARALLDGYPVGQLQQRFPNVAELLDAVRPRYDSDLGARLAVAHALAL 148 +++RALDR RV AR LLDGY QL+ RFPNVAELLD VR R+ D ARLAVA+ +AL Sbjct 71 VVDRALDRQMRVWARTLLDGYSAEQLRTRFPNVAELLDYVRTRHGDDSRARLAVANYMAL 130 Query 149 QFGWRLFAPMLRSATGIDELTGDELRLSVNDAVARILEPH 188 Q GWRLF PMLRSATG+DEL ELR +V ARILEPH Sbjct 131 QLGWRLFEPMLRSATGLDELPQAELRQAVIAEAARILEPH 170 >gi|341603351|emb|CCC66032.1| BCGM3439c [Mycobacterium bovis BCG str. Moreau RDJ] Length=132 Score = 197 bits (502), Expect = 4e-49, Method: Compositional matrix adjust. Identities = 101/110 (92%), Positives = 102/110 (93%), Gaps = 0/110 (0%) Query 1 MTTRPATDRRKMPTGREEVAAAILQAATDLFAERGPAATSIRDIAARSKVNHGLVFRHFG 60 MTTRPATDRRKMPTGREEVAAAILQAATDLFAERGPAATSIRDIAARSKVNHGLVFRHFG Sbjct 1 MTTRPATDRRKMPTGREEVAAAILQAATDLFAERGPAATSIRDIAARSKVNHGLVFRHFG 60 Query 61 TKDQLVGAVLDHLGTKLTRLLHSEAPADIIERALDRHGRVLARALLDGYP 110 TKDQLVGAVLDHLGTKLTRLLHSEAPADIIERALDRHG V A+ P Sbjct 61 TKDQLVGAVLDHLGTKLTRLLHSEAPADIIERALDRHGLVCRLAVSVSTP 110 >gi|317507389|ref|ZP_07965124.1| tetR family bacterial regulatory protein [Segniliparus rugosus ATCC BAA-974] gi|316254337|gb|EFV13672.1| tetR family bacterial regulatory protein [Segniliparus rugosus ATCC BAA-974] Length=199 Score = 159 bits (401), Expect = 2e-37, Method: Compositional matrix adjust. Identities = 91/172 (53%), Positives = 114/172 (67%), Gaps = 0/172 (0%) Query 13 PTGREEVAAAILQAATDLFAERGPAATSIRDIAARSKVNHGLVFRHFGTKDQLVGAVLDH 72 PTGR+ V AA L AA++LFA++GP+ATSIRDIA R+ VNHGLVFR+FG K+QL+GA LD+ Sbjct 15 PTGRDAVVAATLTAASELFAQKGPSATSIRDIATRAGVNHGLVFRYFGAKEQLLGATLDY 74 Query 73 LGTKLTRLLHSEAPADIIERALDRHGRVLARALLDGYPVGQLQQRFPNVAELLDAVRPRY 132 L T L + A D + A DR V RA LDGYP G+LQ RFP + LL VR R Sbjct 75 LADLATSLRQAGADPDEVRAAEDRQLLVGVRATLDGYPAGRLQSRFPGMELLLAEVRRRN 134 Query 133 DSDLGARLAVAHALALQFGWRLFAPMLRSATGIDELTGDELRLSVNDAVARI 184 + AR+A AHA+AL GWRLF P LR+ G+D+L+ EL + RI Sbjct 135 PDERAARIATAHAVALHLGWRLFGPGLRAGLGLDDLSEAELNARIATECDRI 186 >gi|169627190|ref|YP_001700839.1| putative transcriptional regulator [Mycobacterium abscessus ATCC 19977] gi|169239157|emb|CAM60185.1| Putative transcriptional regulator [Mycobacterium abscessus] Length=186 Score = 158 bits (399), Expect = 5e-37, Method: Compositional matrix adjust. Identities = 92/188 (49%), Positives = 128/188 (69%), Gaps = 2/188 (1%) Query 1 MTTRPATDRRKMPTGREEVAAAILQAATDLFAERGPAATSIRDIAARSKVNHGLVFRHFG 60 MTT ATD + P G+EEV A+L AA+ LFAE+GPAATSIR++A R+ VNHGLV RHFG Sbjct 1 MTTPEATDAK--PVGKEEVVEAVLTAASALFAEKGPAATSIREVATRAGVNHGLVHRHFG 58 Query 61 TKDQLVGAVLDHLGTKLTRLLHSEAPADIIERALDRHGRVLARALLDGYPVGQLQQRFPN 120 +K QL+ A L HL + + AP + +E A D RV+ R+ LDG+P+ +LQ+R P Sbjct 59 SKRQLLAATLQHLADTAAAVREAGAPIEELEAAHDLQLRVMVRSTLDGFPIEELQERKPG 118 Query 121 VAELLDAVRPRYDSDLGARLAVAHALALQFGWRLFAPMLRSATGIDELTGDELRLSVNDA 180 +A LL+ VRP + + ARLA AHA+ALQ GWRL P LR+ G+D+++ ++R + Sbjct 119 MAWLLEQVRPGHADERDARLAAAHAIALQLGWRLMGPSLRAGFGLDDMSDADMRAEIAQQ 178 Query 181 VARILEPH 188 +A+I+ PH Sbjct 179 IAKIVTPH 186 >gi|126433594|ref|YP_001069285.1| TetR family transcriptional regulator [Mycobacterium sp. JLS] gi|126233394|gb|ABN96794.1| transcriptional regulator, TetR family [Mycobacterium sp. JLS] Length=190 Score = 155 bits (392), Expect = 3e-36, Method: Compositional matrix adjust. Identities = 80/145 (56%), Positives = 102/145 (71%), Gaps = 0/145 (0%) Query 23 ILQAATDLFAERGPAATSIRDIAARSKVNHGLVFRHFGTKDQLVGAVLDHLGTKLTRLLH 82 +L A DLFAERGPAAT++RDIAARSKVN GL+FRH G K+ +V AVLD L L Sbjct 19 VLSHAADLFAERGPAATTLRDIAARSKVNAGLIFRHIGNKEAVVAAVLDQLADDLIAARD 78 Query 83 SEAPADIIERALDRHGRVLARALLDGYPVGQLQQRFPNVAELLDAVRPRYDSDLGARLAV 142 + + + +E +R +V+ARALLDGY VG+LQ+ FPNV +L+ R R + AR+A Sbjct 79 AGSSREEVEARAERSWKVIARALLDGYDVGRLQRGFPNVEQLVAVARERQGDEYAARVAT 138 Query 143 AHALALQFGWRLFAPMLRSATGIDE 167 A ALALQ GWRLF P LR+ATG+D+ Sbjct 139 ADALALQLGWRLFGPFLRAATGLDD 163 >gi|118469617|ref|YP_884596.1| HTH-type transcriptional regulator [Mycobacterium smegmatis str. MC2 155] gi|118170904|gb|ABK71800.1| putative HTH-type transcriptional regulator [Mycobacterium smegmatis str. MC2 155] Length=169 Score = 150 bits (380), Expect = 7e-35, Method: Compositional matrix adjust. Identities = 84/145 (58%), Positives = 105/145 (73%), Gaps = 0/145 (0%) Query 23 ILQAATDLFAERGPAATSIRDIAARSKVNHGLVFRHFGTKDQLVGAVLDHLGTKLTRLLH 82 +L A DLFAERGPAATS+RD+A RS VN GL+FRH G K+ LV AVLD L +L Sbjct 19 VLTHAADLFAERGPAATSLRDVAERSGVNAGLIFRHIGNKEALVAAVLDFLADELVTARG 78 Query 83 SEAPADIIERALDRHGRVLARALLDGYPVGQLQQRFPNVAELLDAVRPRYDSDLGARLAV 142 ++AP ++IE ++R +V+ARALLDGY VG LQ RFP V EL++A R R+ D AR A Sbjct 79 TDAPEEVIEAHVERSWKVIARALLDGYDVGALQHRFPVVEELVEAARQRHQDDHAARAAT 138 Query 143 AHALALQFGWRLFAPMLRSATGIDE 167 A A+ALQ GWRLF P LR+ATG+D+ Sbjct 139 ADAIALQLGWRLFGPFLRAATGLDD 163 >gi|218780279|ref|YP_002431597.1| TetR family transcriptional regulator [Desulfatibacillum alkenivorans AK-01] gi|218761663|gb|ACL04129.1| transcriptional regulator, TetR family [Desulfatibacillum alkenivorans AK-01] Length=199 Score = 95.1 bits (235), Expect = 4e-18, Method: Compositional matrix adjust. Identities = 62/185 (34%), Positives = 95/185 (52%), Gaps = 20/185 (10%) Query 9 RRKMPTGREEVAAAILQAATDLFAERGPAATSIRDIAARSKVNHGLVFRHFGTKDQLVGA 68 +++ P GR+EV A++L+AA++LFA +G A S+RDIAA++ VNHGL+ RHFG+K+ L Sbjct 3 KKRKPHGRDEVMASVLEAASELFANKGVAGVSVRDIAAKAGVNHGLIHRHFGSKEVLRRQ 62 Query 69 VLDHLGTKLTRLLHSEAPADIIERAL----------DRHGRVLARALLDGYPVGQLQQRF 118 + L L+ P E + D + RVLAR LLDG G++Q F Sbjct 63 TQEKLSAD---LIGEMGPGSSFEETMSMAWAALLKHDAYWRVLARTLLDGKWQGEIQSDF 119 Query 119 PNVAELLDAVRP-----RYDSDLGARLAVAHALALQFGWRLFAPMLRSATGIDELTGDEL 173 P V + + R D ++ VA +A+ G +F + +A + + GD L Sbjct 120 PFVDLAVQMAKKEQEQGRVIEDADPKMIVAGIMAMALGLEVFQDYILTAAKLKD--GDPL 177 Query 174 RLSVN 178 N Sbjct 178 ETKAN 182 >gi|218783005|ref|YP_002434323.1| TetR family transcriptional regulator [Desulfatibacillum alkenivorans AK-01] gi|218764389|gb|ACL06855.1| transcriptional regulator, TetR family [Desulfatibacillum alkenivorans AK-01] Length=194 Score = 90.5 bits (223), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 62/174 (36%), Positives = 90/174 (52%), Gaps = 16/174 (9%) Query 7 TDRRKMPTGREEVAAAILQAATDLFAERGPAATSIRDIAARSKVNHGLVFRHFGTKDQLV 66 T + P G+ V AIL+A+T LFAE+G AA S RDIAA++ VN GL+ RHF TK+ + Sbjct 2 TAKTNKPMGKAAVMEAILEASTALFAEKGIAAVSWRDIAAKANVNPGLIHRHFRTKENIR 61 Query 67 GAVLDHLGTKLTRLLHSEAPADIIE---------RALDRHGRVLARALLDGYPVGQLQQR 117 V D L ++ + + P D E R D +V+AR LDG G +Q Sbjct 62 LQVQDRLMEEINKDIGE--PGDPEEALVNGVLALRKNDAFWKVMARTFLDGKFEGDVQTS 119 Query 118 FPNVAELLDAVRPRYD-----SDLGARLAVAHALALQFGWRLFAPMLRSATGID 166 FP + +++D++ D S + + VA A+ G LF + ATG+D Sbjct 120 FPFLQKMVDSLNTAQDAGTITSRVDPTMLVAGGTAMALGLLLFEKYILPATGLD 173 >gi|311744261|ref|ZP_07718065.1| TetR family transcriptional regulator [Aeromicrobium marinum DSM 15272] gi|311312434|gb|EFQ82347.1| TetR family transcriptional regulator [Aeromicrobium marinum DSM 15272] Length=191 Score = 80.1 bits (196), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 69/190 (37%), Positives = 99/190 (53%), Gaps = 24/190 (12%) Query 13 PTGREEVAAAILQAATDLFAERGPAATSIRDIAARSKVNHGLVFRHFGTK----DQLVGA 68 P GR++V +A+L AA++L AERGP S+RDIA R+ VNH LV RHFGTK +Q++ A Sbjct 9 PRGRDQVRSAVLTAASELVAERGPDRFSVRDIAERAGVNHALVHRHFGTKADVMEQMLAA 68 Query 69 ----VLDH-LGTKLTRLLHSEAPADIIERALD------RHGRVLARALLDGYPVGQLQQR 117 V+D LG+ L EA ++ LD + R L +A+LD P L Sbjct 69 DARVVVDAILGSGLP--TDGEATPSVVADLLDLLAARPSYWRTLVQAVLDS-PEAALPGT 125 Query 118 FPNVAELLDAVRPRYDSDLGARLAVAHALALQFGWRLFAPMLRSATGIDELTGDELRLSV 177 A L + D+D +VA AL GW +F P + +TG D ++R +V Sbjct 126 ASTTA-LFSDLWAGGDADRATSTSVAGITAL--GWLIFGPFMAESTGADPA---DVRRAV 179 Query 178 NDAVARILEP 187 + +A +L P Sbjct 180 AEQMAALLTP 189 >gi|326382361|ref|ZP_08204053.1| transcriptional regulator [Gordonia neofelifaecis NRRL B-59395] gi|326199091|gb|EGD56273.1| transcriptional regulator [Gordonia neofelifaecis NRRL B-59395] Length=192 Score = 73.9 bits (180), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 52/166 (32%), Positives = 82/166 (50%), Gaps = 13/166 (7%) Query 14 TGREEVAAAILQAATDLFAERGPAATSIRDIAARSKVNHGLVFRHFGTKDQLVGAVLDHL 73 T +E I+ AA +L+AERGP+ S+R +A + VN+GL+ ++ G+KDQL+ V L Sbjct 9 TSKERDTDKIVDAALELYAERGPSRVSLRQVAQHAGVNYGLIHQYVGSKDQLLELVFTRL 68 Query 74 GTKLTRLLHSEAPADIIERAL--------DRHGRVLARALLDGYPVGQLQQRFPNVAELL 125 + AD E A+ D + R+LA +L+G G+ + P + EL+ Sbjct 69 SETWADAF---SAADGTESAVAVLLRPKSDAYVRLLAHLILEGRDPGEFFKAPPALRELV 125 Query 126 DAVRPRYDSDLGARLAVAHALALQFGWRLFAPMLRSATGIDELTGD 171 + D D ARL A + GW LF P ++ + + GD Sbjct 126 RRLEDGGDED--ARLQAAVLTCMSMGWGLFGPHVKDLADLSDSEGD 169 >gi|312197983|ref|YP_004018044.1| TetR family transcriptional regulator [Frankia sp. EuI1c] gi|311229319|gb|ADP82174.1| regulatory protein TetR [Frankia sp. EuI1c] Length=221 Score = 68.9 bits (167), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 52/167 (32%), Positives = 85/167 (51%), Gaps = 11/167 (6%) Query 11 KMPTGREEVAAAILQAATDLFAERGPAATSIRDIAARSKVNHGLVFRHFGTKDQLVGAVL 70 + P GR+EV A+L+AA L AE+GPA +R++A ++VN GLV+++ GTK+ L+ V Sbjct 22 RRPRGRQEVREALLEAAQRLIAEQGPANVRLREVADAARVNFGLVYQYLGTKEDLLHEVY 81 Query 71 DHLGTKLT-RLLHSEAPADIIERAL----DRHGRVLARALLDGYPVGQLQQRFPNVAELL 125 + + R EA D+++ L D GR++ L+G + P ++++ Sbjct 82 QRVAARSAGRFEQVEALTDVVDIFLTIADDSIGRIMGWVALEGGYSADVFGPSPALSQVA 141 Query 126 DAV----RPRYDS--DLGARLAVAHALALQFGWRLFAPMLRSATGID 166 V R + D AR+ A + GWRLF P+ S +D Sbjct 142 GIVARDARAHGNEVPDEEARVFAAFLQLVALGWRLFRPIGLSIADVD 188 >gi|302547787|ref|ZP_07300129.1| putative TetR-family transcriptional regulator [Streptomyces hygroscopicus ATCC 53653] gi|302465405|gb|EFL28498.1| putative TetR-family transcriptional regulator [Streptomyces himastatinicus ATCC 53653] Length=245 Score = 67.4 bits (163), Expect = 9e-10, Method: Compositional matrix adjust. Identities = 58/180 (33%), Positives = 89/180 (50%), Gaps = 27/180 (15%) Query 23 ILQAATDLFAERGPAATSIRDIAARSKVNHGLVFRHFGTKDQLVGAVLDHLGTKLTRLLH 82 +L+AA+ LFAERG ++RDIA R+ VN L+FR+FG+K L G V+ H G + LH Sbjct 57 LLEAASALFAERGYERATVRDIAERAGVNQALLFRYFGSKKALFGEVVSHDGQE---QLH 113 Query 83 SEAPADIIERAL------------DRHGRVLARALLDGYPVGQ-LQQRFPNVAELLDAVR 129 + P ++ E AL DR L R++ G +G ++ + A +L ++ Sbjct 114 TTPPRELFETALRGMLGHGDRTREDRALATLLRSVGSGDEIGTAVRDMGDDYARVLASLS 173 Query 130 PRYDSDLGARLAVAHALALQFGWRLFAPMLRSATGIDELTG---DELRLSVNDAVARILE 186 D L A LA++ W L ++R G + L DE+ V A+A +LE Sbjct 174 SAEDRGLRADLALS--------WMLGIGLMRVVVGKESLAEADPDEVCALVTGALATLLE 225 >gi|288916092|ref|ZP_06410473.1| transcriptional regulator, TetR family [Frankia sp. EUN1f] gi|288352488|gb|EFC86684.1| transcriptional regulator, TetR family [Frankia sp. EUN1f] Length=220 Score = 65.9 bits (159), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 56/167 (34%), Positives = 86/167 (52%), Gaps = 18/167 (10%) Query 18 EVAAAILQAATDLFAERGPAATSIRDIAARSKVNHGLVFRHFGTKDQLVGAVLDHLGTK- 76 EV A+L++A L A++GP+ +R+IA + VN GLV+++ GT+++L+ AV + + Sbjct 37 EVREALLESAQRLIAQQGPSKVRLREIAEAADVNFGLVYQYLGTREELLRAVYQRVSARS 96 Query 77 LTRLLHSEAPADIIERAL---DRHGRVLARALLDGYPVG------QLQQRFPNVAELLDA 127 TR H + AD I+ L D GR++ A L+G P LQQ VA ++ Sbjct 97 ATRFEHIDDLADAIDIFLTADDSVGRIMGWAALEGDPADVFGPSPGLQQ----VASMMVR 152 Query 128 VRPRYDSDL---GARLAVAHALALQFGWRLFAPMLRSATGIDELTGD 171 + DL ARL A + GWRLF + + G+ E T D Sbjct 153 AARQDGLDLPEDEARLLAAFLQVVALGWRLFGSIGLTGAGV-EATSD 198 >gi|226525269|gb|ACO70869.1| transcriptional regulator TetR family [uncultured Verrucomicrobia bacterium] Length=211 Score = 60.8 bits (146), Expect = 9e-08, Method: Compositional matrix adjust. Identities = 47/151 (32%), Positives = 81/151 (54%), Gaps = 10/151 (6%) Query 23 ILQAATDLFAERGPAATSIRDIAARSKVNHGLVFRHFGTKDQLVGAVLD-HLGTKLTRLL 81 +L AA + A+RG A + R+IA +KVN +FRHFG+K++L+ A+ + + ++ L Sbjct 16 LLDAAFSVCAQRGLHAATTREIADAAKVNEVTLFRHFGSKEKLIAALFERSVSAQIQSLS 75 Query 82 HSEAPADIIERALDRHGRVLARALLDGYP-----VGQLQQRFPNVAE--LLDAVRPRYDS 134 SE+ D + R L R+ R + L + P +G+ R+P A + D+V+P Sbjct 76 DSESDGDDLARDLLRYARKFNQMLFEHEPLIRTLIGE-AHRYPEAAREVIQDSVKPMRRR 134 Query 135 DLGARLAVAHALALQFGWRLFAPMLRSATGI 165 + A A A++ G +L AP + + TG+ Sbjct 135 LIAYLRAAQEAGAVRTGLKL-APAVDAFTGM 164 >gi|297162534|gb|ADI12246.1| TetR family transcriptional regulator [Streptomyces bingchenggensis BCW-1] Length=187 Score = 60.5 bits (145), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 33/72 (46%), Positives = 47/72 (66%), Gaps = 3/72 (4%) Query 23 ILQAATDLFAERGPAATSIRDIAARSKVNHGLVFRHFGTKDQLVGAVLDHLGTKLTRLLH 82 +L+AA+ LFAERG T++RDIA R+ N L+FR+FG+K L G V+ H G + R Sbjct 1 MLEAASALFAERGYERTTVRDIADRAGANQALLFRYFGSKRALFGEVVAHDGEEQMR--- 57 Query 83 SEAPADIIERAL 94 S P +++E AL Sbjct 58 STPPDELLEAAL 69 >gi|228991428|ref|ZP_04151383.1| Transcriptional regulator, TetR [Bacillus pseudomycoides DSM 12442] gi|228768358|gb|EEM16966.1| Transcriptional regulator, TetR [Bacillus pseudomycoides DSM 12442] Length=219 Score = 59.3 bits (142), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 44/144 (31%), Positives = 71/144 (50%), Gaps = 13/144 (9%) Query 6 ATDRRKMPTGREEVAAAILQAATDLFAERGPAATSIRDIAARSKVNHGLVFRHFGTKDQL 65 ATD K R E IL+AA D+F E+G A+TS +IA R+ V G +FR++ TK L Sbjct 12 ATDTDK----RNERQMRILEAAVDMFGEKGYASTSTSEIAKRAGVAEGTIFRYYKTKKDL 67 Query 66 VGAVLDHLGTKLTRLLHSEAPA-DIIERALDRHGRVLARALLDGYPVGQ--------LQQ 116 + AV+ TK +A A +I+E + + L +A+ + + + L Q Sbjct 68 LLAVVMPTLTKFAAPFFVQAFAKEILENTYETYEEFLRKAIRNRFEFAKKHFPMLKILIQ 127 Query 117 RFPNVAELLDAVRPRYDSDLGARL 140 P EL + ++ + +L +R Sbjct 128 EVPFQPELKNEIQQLVEKELFSRF 151 >gi|228997532|ref|ZP_04157147.1| Transcriptional regulator, TetR [Bacillus mycoides Rock3-17] gi|229005157|ref|ZP_04162880.1| Transcriptional regulator, TetR [Bacillus mycoides Rock1-4] gi|228756132|gb|EEM05454.1| Transcriptional regulator, TetR [Bacillus mycoides Rock1-4] gi|228762224|gb|EEM11155.1| Transcriptional regulator, TetR [Bacillus mycoides Rock3-17] Length=219 Score = 59.3 bits (142), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 44/144 (31%), Positives = 71/144 (50%), Gaps = 13/144 (9%) Query 6 ATDRRKMPTGREEVAAAILQAATDLFAERGPAATSIRDIAARSKVNHGLVFRHFGTKDQL 65 ATD K R E IL+AA D+F E+G A+TS +IA R+ V G +FR++ TK L Sbjct 12 ATDTDK----RNERQMRILEAAVDMFGEKGYASTSTSEIAKRAGVAEGTIFRYYKTKKDL 67 Query 66 VGAVLDHLGTKLTRLLHSEAPA-DIIERALDRHGRVLARALLDGYPVGQ--------LQQ 116 + AV+ TK +A A +I+E + + L +A+ + + + L Q Sbjct 68 LLAVVMPTLTKFAAPFFVQAFAKEILENTYETYEEFLRKAIRNRFEFAKKHFPMLKILIQ 127 Query 117 RFPNVAELLDAVRPRYDSDLGARL 140 P EL + ++ + +L +R Sbjct 128 EVPFQPELKNEIQQLVEKELFSRF 151 >gi|296120826|ref|YP_003628604.1| regulatory protein TetR [Planctomyces limnophilus DSM 3776] gi|296013166|gb|ADG66405.1| regulatory protein TetR [Planctomyces limnophilus DSM 3776] Length=251 Score = 59.3 bits (142), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 44/122 (37%), Positives = 60/122 (50%), Gaps = 14/122 (11%) Query 4 RPATDRRKMPTGREEVAAAILQAATDLFAERGPAATSIRDIAARSKVNHGLVFRHFGTKD 63 RPA P R++ ILQAA LFAE+G A T ++++A R V G V+R+F TK Sbjct 20 RPAN-----PQLRKQREEEILQAAAALFAEKGYAPTDLQELAQRLGVGKGTVYRYFPTKQ 74 Query 64 QLVGAVLDHLGTKLTRLLHSEAPADIIERALDRHGRVLARALLDGYPVGQLQQRFPNVAE 123 L A + H T+ T L S P D L ++ A L Q Q+ P+V E Sbjct 75 DLFLATVKHEITRFTTTLESMVPRDA---PLIEQMSLVIEAYL------QFFQQNPDVVE 125 Query 124 LL 125 L+ Sbjct 126 LM 127 >gi|229085423|ref|ZP_04217664.1| Transcriptional regulator, TetR [Bacillus cereus Rock3-44] gi|228697899|gb|EEL50643.1| Transcriptional regulator, TetR [Bacillus cereus Rock3-44] Length=217 Score = 59.3 bits (142), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 40/134 (30%), Positives = 68/134 (51%), Gaps = 9/134 (6%) Query 16 REEVAAAILQAATDLFAERGPAATSIRDIAARSKVNHGLVFRHFGTKDQLVGAVLDHLGT 75 R E IL+AA D+F E+G A+TS +IA R+ V G +FR++ TK L+ AV+ T Sbjct 18 RNERQLRILEAAVDMFGEKGYASTSTSEIAKRAGVAEGTIFRYYKTKKDLLLAVVMPTLT 77 Query 76 KLTRLLHSEAPA-DIIERALDRHGRVLARALLDGYPVGQ--------LQQRFPNVAELLD 126 K +A A +I+E+ + + L +A+ + + + L Q P EL + Sbjct 78 KFAAPFFIQAFAKEILEKTYETYEEFLRKAIRNRFEFAKKHFPMLKILIQEVPFQPELKN 137 Query 127 AVRPRYDSDLGARL 140 ++ + +L +R Sbjct 138 EIQQLVEKELFSRF 151 >gi|134098011|ref|YP_001103672.1| TetR family transcriptional regulator [Saccharopolyspora erythraea NRRL 2338] gi|291007224|ref|ZP_06565197.1| TetR family transcriptional regulator [Saccharopolyspora erythraea NRRL 2338] gi|133910634|emb|CAM00747.1| transcriptional regulator, TetR family [Saccharopolyspora erythraea NRRL 2338] Length=188 Score = 58.5 bits (140), Expect = 5e-07, Method: Compositional matrix adjust. Identities = 26/49 (54%), Positives = 37/49 (76%), Gaps = 0/49 (0%) Query 22 AILQAATDLFAERGPAATSIRDIAARSKVNHGLVFRHFGTKDQLVGAVL 70 A+L+AA +LFAERG ++RD+AAR+ VN L+FR+FG+K +L VL Sbjct 17 ALLRAAAELFAERGFEQATVRDVAARAGVNQALLFRYFGSKQELFAEVL 65 >gi|319948030|ref|ZP_08022206.1| transcriptional regulator [Dietzia cinnamea P4] gi|319438319|gb|EFV93263.1| transcriptional regulator [Dietzia cinnamea P4] Length=192 Score = 58.2 bits (139), Expect = 6e-07, Method: Compositional matrix adjust. Identities = 30/58 (52%), Positives = 41/58 (71%), Gaps = 1/58 (1%) Query 13 PTGREEVAAAILQAATDLFAERGPAATSIRDIAARSKVNHGLVFRHFGTKDQLVGAVL 70 PTGR+EV +A+L+ A L +ERGP +RDIA ++VN GL+ RH G KD L+ AV+ Sbjct 12 PTGRDEVRSAVLREARRLLSERGPH-VPLRDIADAAQVNLGLIHRHIGRKDALITAVM 68 >gi|300785854|ref|YP_003766145.1| TetR family transcriptional regulator [Amycolatopsis mediterranei U32] gi|299795368|gb|ADJ45743.1| TetR family transcriptional regulator [Amycolatopsis mediterranei U32] gi|340527319|gb|AEK42524.1| TetR family transcriptional regulator [Amycolatopsis mediterranei S699] Length=189 Score = 58.2 bits (139), Expect = 7e-07, Method: Compositional matrix adjust. Identities = 34/65 (53%), Positives = 41/65 (64%), Gaps = 6/65 (9%) Query 1 MTTRPATDRRKMPTGREEVAAAILQAATDLFAERGPAATSIRDIAARSKVNHGLVFRHFG 60 MT RP R+ P G + AIL AA F ERG A ++RDIAAR+ V HGLV R FG Sbjct 1 MTRRP---HRRDPEGHRQ---AILDAARASFGERGFARATVRDIAARAGVTHGLVLRQFG 54 Query 61 TKDQL 65 +K+QL Sbjct 55 SKEQL 59 >gi|337769606|emb|CCB78319.1| Transcriptional regulator, TetR family [Streptomyces cattleya NRRL 8057] Length=200 Score = 57.8 bits (138), Expect = 8e-07, Method: Compositional matrix adjust. Identities = 35/73 (48%), Positives = 48/73 (66%), Gaps = 3/73 (4%) Query 22 AILQAATDLFAERGPAATSIRDIAARSKVNHGLVFRHFGTKDQLVGAVLDHLGTKLTRLL 81 A+L AA+ LFAERG T++R IAAR+ N L+FR+FG+K L G V+ G + RLL Sbjct 21 ALLDAASVLFAERGYERTTVRAIAARAGANQALLFRYFGSKRALFGEVMARNGRQ--RLL 78 Query 82 HSEAPADIIERAL 94 +E P ++E AL Sbjct 79 ATE-PERLLEVAL 90 >gi|149188374|ref|ZP_01866668.1| transcriptional regulator, TetR family protein [Vibrio shilonii AK1] gi|148837963|gb|EDL54906.1| transcriptional regulator, TetR family protein [Vibrio shilonii AK1] Length=239 Score = 57.8 bits (138), Expect = 8e-07, Method: Compositional matrix adjust. Identities = 30/82 (37%), Positives = 44/82 (54%), Gaps = 3/82 (3%) Query 10 RKMPTGREEVAAAILQAATDLFAERGPAATSIRDIAARSKVNHGLVFRHFGTKDQLVGAV 69 R+ T EE I+ A ++F E G SIR+I+ R+ V+H L+ HFG+K+Q+ + Sbjct 7 RRSATAAEETKNLIMTVAAEMFCELGYERVSIRNISERAGVSHSLIRHHFGSKEQIWYGI 66 Query 70 LDHLG---TKLTRLLHSEAPAD 88 DHL K R L + P D Sbjct 67 SDHLHAYMQKYIRYLLDQLPED 88 >gi|322436748|ref|YP_004218960.1| regulatory protein TetR [Acidobacterium sp. MP5ACTX9] gi|321164475|gb|ADW70180.1| regulatory protein TetR [Acidobacterium sp. MP5ACTX9] Length=194 Score = 57.4 bits (137), Expect = 9e-07, Method: Compositional matrix adjust. Identities = 35/98 (36%), Positives = 49/98 (50%), Gaps = 0/98 (0%) Query 23 ILQAATDLFAERGPAATSIRDIAARSKVNHGLVFRHFGTKDQLVGAVLDHLGTKLTRLLH 82 IL+AA LF G AT I + S+V +RHF +KD LV A L++ L Sbjct 16 ILEAADRLFYTEGVRATGTEKIMSVSEVAKATFYRHFPSKDDLVTAYLEYRDRSFFEYLD 75 Query 83 SEAPADIIERALDRHGRVLARALLDGYPVGQLQQRFPN 120 S AP + I AL R RV+ R + G P ++ +P+ Sbjct 76 SPAPPEDIHEALARIERVVNRVDIIGCPFLRIASEYPD 113 >gi|308049886|ref|YP_003913452.1| TetR family transcriptional regulator [Ferrimonas balearica DSM 9799] gi|307632076|gb|ADN76378.1| transcriptional regulator, TetR family [Ferrimonas balearica DSM 9799] Length=236 Score = 57.4 bits (137), Expect = 9e-07, Method: Compositional matrix adjust. Identities = 42/145 (29%), Positives = 72/145 (50%), Gaps = 10/145 (6%) Query 10 RKMPTGREEVAAAILQAATDLFAERGPAATSIRDIAARSKVNHGLVFRHFGTKDQLVGAV 69 R+ E+ +IL AA DLF+++G S+R+I+ + V+HGL+ HFG+K+Q+ + Sbjct 8 RQSAEAAEQTKKSILCAAADLFSQKGFDKVSVREISEVAGVSHGLIRHHFGSKEQIWHRI 67 Query 70 LDHLGTKLTRLLHS---EAPADI--IERALDRHGRVLARALLDGYPVGQLQQRFPNVAEL 124 D + + L+ + EA ++ ER + R++A L+D P + EL Sbjct 68 CDEIHLYIQGLMETLVEEADPNLPPNERLFEMMIRLMASLLVDPRPSRLAASAMGSKEEL 127 Query 125 LDAVRPRYDSDLGARLAVAHALALQ 149 D Y DL + A A+ L+ Sbjct 128 FD-----YLYDLTGKTEKAFAMELE 147 >gi|89895559|ref|YP_519046.1| hypothetical protein DSY2813 [Desulfitobacterium hafniense Y51] gi|89335007|dbj|BAE84602.1| hypothetical protein [Desulfitobacterium hafniense Y51] Length=202 Score = 57.4 bits (137), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 28/70 (40%), Positives = 43/70 (62%), Gaps = 0/70 (0%) Query 16 REEVAAAILQAATDLFAERGPAATSIRDIAARSKVNHGLVFRHFGTKDQLVGAVLDHLGT 75 +E+ A+L+AA LFA++G T + DIA + V+HG VF HF T++ L+ V++ G Sbjct 10 KEQTKEALLKAAYQLFAKQGIMNTRMSDIAQAAGVSHGTVFAHFQTQEMLITEVIETYGE 69 Query 76 KLTRLLHSEA 85 K+ R H A Sbjct 70 KIARRTHEAA 79 >gi|256822023|ref|YP_003145986.1| TetR family transcriptional regulator [Kangiella koreensis DSM 16069] gi|256795562|gb|ACV26218.1| transcriptional regulator, TetR family [Kangiella koreensis DSM 16069] Length=209 Score = 57.0 bits (136), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 32/71 (46%), Positives = 39/71 (55%), Gaps = 0/71 (0%) Query 14 TGREEVAAAILQAATDLFAERGPAATSIRDIAARSKVNHGLVFRHFGTKDQLVGAVLDHL 73 T E + IL AA LFAERG A TS+R I R++VN V HFG+K L+ AV D Sbjct 2 TKTESTKSRILDAAEQLFAERGFAETSLRTITTRARVNLASVNYHFGSKKSLIQAVFDRF 61 Query 74 GTKLTRLLHSE 84 T+ L E Sbjct 62 LQDFTKELSLE 72 >gi|345001669|ref|YP_004804523.1| TetR family transcriptional regulator [Streptomyces sp. SirexAA-E] gi|344317295|gb|AEN11983.1| transcriptional regulator, TetR family [Streptomyces sp. SirexAA-E] Length=200 Score = 56.2 bits (134), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 37/97 (39%), Positives = 51/97 (53%), Gaps = 5/97 (5%) Query 1 MTTRPATDRRKMPTGREEVAAAILQAATDLFAERGPAATSIRDIAARSKVNHGLVFRHFG 60 M+TRP R + P + I AA +LF E G A IR +AAR+ V+ LV RHFG Sbjct 1 MSTRPRAARPRQPAAVTR--STIFDAARELFGESGFDAVGIRAVAARAGVDAALVIRHFG 58 Query 61 TKDQLVGAVLDHLGTKLTRLLHSEAPADIIERALDRH 97 +K+QL L+ + L + E P D + RA+ H Sbjct 59 SKEQL---FLETMTVDLPAVRVMEGPLDGMGRAIVEH 92 >gi|149923989|ref|ZP_01912374.1| probable transcriptional regulator, TetR/AcrR family protein [Plesiocystis pacifica SIR-1] gi|149815167|gb|EDM74718.1| probable transcriptional regulator, TetR/AcrR family protein [Plesiocystis pacifica SIR-1] Length=216 Score = 56.2 bits (134), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 43/112 (39%), Positives = 58/112 (52%), Gaps = 8/112 (7%) Query 10 RKMPTGREEVAAA----ILQAATDLFAERGPAATSIRDIAARSKVNHGLVFRHFGTKDQL 65 RK T R+ A A I AA LFAE G A TS R IA ++ V+ GL+F HF K L Sbjct 4 RKAKTARQRQAEATKKNIADAALRLFAEHGVAGTSTRSIAKQAGVSEGLIFHHFPDKMAL 63 Query 66 VGAVL---DHLGTKLTRLLHSEAPADIIERALDRHGRVLARALLDGYPVGQL 114 + AV GT++ +LL A A + LD R+ ++ ++ G P QL Sbjct 64 LAAVAATRTTFGTEVVKLLEG-ADARPLTEILDDMARMFSKLVVAGTPEAQL 114 >gi|114798426|ref|YP_761142.1| TetR family transcriptional regulator [Hyphomonas neptunium ATCC 15444] gi|114738600|gb|ABI76725.1| transcriptional regulator, TetR family [Hyphomonas neptunium ATCC 15444] Length=236 Score = 56.2 bits (134), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 38/109 (35%), Positives = 55/109 (51%), Gaps = 9/109 (8%) Query 4 RPATDRRKMPTG--REEVAAAILQAATDLFAERGPAATSIRDIAARSKVNHGLVFRHFGT 61 +PA +MP EE A IL AA FA+RG A +IRDIA + V H L+ HFG+ Sbjct 10 KPAAPPARMPQQARSEESRANILDAARKAFAQRGFEAANIRDIATDAGVTHTLIRYHFGS 69 Query 62 KDQLVGAVLDHLGTKLTRLLHS-------EAPADIIERALDRHGRVLAR 103 K++L V+ H+ +L+ + +P D + L + R AR Sbjct 70 KEELWKEVVTHMFERLSEEMREGLKGAKGASPQDSLREFLRTYIRYCAR 118 >gi|91776914|ref|YP_546670.1| TetR family transcriptional regulator [Methylobacillus flagellatus KT] gi|91710901|gb|ABE50829.1| transcriptional regulator, TetR family [Methylobacillus flagellatus KT] Length=214 Score = 56.2 bits (134), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 38/99 (39%), Positives = 52/99 (53%), Gaps = 8/99 (8%) Query 4 RPATDRRKMPTGREEVAAAILQAATDLFAERGPAATSIRDIAARSKVNHGLVFRHFGTKD 63 RP RR+ E AA IL A DLFA+ A+ + + IAA SKVN L++ +F KD Sbjct 5 RPKVARRERG---ETQAANILSVALDLFAKHHVASVTTKQIAAASKVNSALLYYYFKNKD 61 Query 64 QLVGAVLDH-LGTKLTRLLHSE----APADIIERALDRH 97 L +DH +G L R H + PA+I+ L+ H Sbjct 62 DLFRQAVDHAIGQVLLRFEHVQKTAHGPAEILSAWLNLH 100 >gi|337746706|ref|YP_004640868.1| TetR family transcriptional regulator [Paenibacillus mucilaginosus KNP414] gi|336297895|gb|AEI40998.1| transcriptional regulator, TetR family [Paenibacillus mucilaginosus KNP414] Length=205 Score = 56.2 bits (134), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 31/86 (37%), Positives = 53/86 (62%), Gaps = 5/86 (5%) Query 16 REEVAAAILQAATDLFAERGPAATSIRDIAARSKVNHGLVFRHFGTKDQLVGAVLDHLGT 75 R+E + IL AA +LFA++G +T I DIA ++ ++HGLV+ +F +K+++ ++LD Sbjct 12 RKERCSQILSAAVELFAKQGLTSTKISDIAKKAGMSHGLVYNYFRSKEEIYLSLLDMNMN 71 Query 76 KLTRLL---HS--EAPADIIERALDR 96 L +L HS P +ER +D+ Sbjct 72 VLENILLWIHSLDRTPKGKLERLIDK 97 >gi|345012662|ref|YP_004815016.1| regulatory protein TetR [Streptomyces violaceusniger Tu 4113] gi|344039011|gb|AEM84736.1| regulatory protein TetR [Streptomyces violaceusniger Tu 4113] Length=197 Score = 56.2 bits (134), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 31/72 (44%), Positives = 45/72 (63%), Gaps = 3/72 (4%) Query 23 ILQAATDLFAERGPAATSIRDIAARSKVNHGLVFRHFGTKDQLVGAVLDHLGTKLTRLLH 82 +++AA LFAERG ++RDIA R+ VN L+FR+FG+K L G V+ H G + R Sbjct 20 LMEAAAALFAERGYERATVRDIADRAGVNQALLFRYFGSKRALFGEVIAHNGEEQLR--- 76 Query 83 SEAPADIIERAL 94 + P ++ E AL Sbjct 77 TTPPHELPETAL 88 >gi|111219807|ref|YP_710601.1| TetR family transcriptional regulator [Frankia alni ACN14a] gi|111147339|emb|CAJ58990.1| putative transcriptional regulator, TETR family [Frankia alni ACN14a] Length=273 Score = 56.2 bits (134), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 28/67 (42%), Positives = 42/67 (63%), Gaps = 0/67 (0%) Query 7 TDRRKMPTGREEVAAAILQAATDLFAERGPAATSIRDIAARSKVNHGLVFRHFGTKDQLV 66 +D R R E A IL AA A RGPA S+RD++A ++V+ G ++R+F TK +L+ Sbjct 52 SDWRHAVGNRFETPAKILDAALGCIAARGPAKMSLRDVSAAAEVSRGTLYRYFKTKGELL 111 Query 67 GAVLDHL 73 A+ DH+ Sbjct 112 TAISDHV 118 >gi|158313472|ref|YP_001505980.1| TetR family transcriptional regulator [Frankia sp. EAN1pec] gi|158108877|gb|ABW11074.1| transcriptional regulator, TetR family [Frankia sp. EAN1pec] Length=226 Score = 56.2 bits (134), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 38/85 (45%), Positives = 48/85 (57%), Gaps = 8/85 (9%) Query 5 PATDRRKMPTGREEVAAAILQAATDLFAERGPAATSIRDIAARSKVNHGLVFRHFGTKDQ 64 P RR +P RE AI+ AA DLF +G AAT++ DIA + V+ V+ HFG K+ Sbjct 8 PPRARRGLPAKRE----AIMAAALDLFVRQGYAATTLDDIATATPVSRQTVYNHFGDKET 63 Query 65 LVGAVLD-HLGTKLTRLLHSEAPAD 88 L AV+D HL L L APAD Sbjct 64 LFRAVIDTHLNATLEAL---HAPAD 85 >gi|117164538|emb|CAJ88084.1| putative TetR-family transcriptional regulator [Streptomyces ambofaciens ATCC 23877] Length=201 Score = 55.8 bits (133), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 46/137 (34%), Positives = 66/137 (49%), Gaps = 7/137 (5%) Query 12 MPTGREEVAAA-----ILQAATDLFAERGPAATSIRDIAARSKVNHGLVFRHFGTKDQLV 66 +PTGR E A I AA LF ERG A IRD+AA + V +F HF +K+ LV Sbjct 3 VPTGRRERKKAATRQKIADAALRLFLERGYDAVGIRDVAAEADVAVTTLFSHFASKEALV 62 Query 67 GAVLDHLGTKLTRLLHSEAPADIIERALDRHGRVLARALLDGY--PVGQLQQRFPNVAEL 124 + +LTR + AP + + AL R + L R G P+ Q+ P + + Sbjct 63 FEQDEDFEQRLTRAVSDRAPHEPLIPALRREIQALVRHCTAGSAAPIWQMIVASPALRKY 122 Query 125 LDAVRPRYDSDLGARLA 141 +A+R R+ L +A Sbjct 123 DEAMRLRHAESLARAIA 139 >gi|111222936|ref|YP_713730.1| putative HTH-type transcriptional regulator [Frankia alni ACN14a] gi|111150468|emb|CAJ62167.1| Putative HTH-type transcriptional regulator [Frankia alni ACN14a] Length=210 Score = 55.5 bits (132), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 59/181 (33%), Positives = 80/181 (45%), Gaps = 36/181 (19%) Query 14 TGREEVAAA--ILQAATDLFAERGPAATSIRDIAARSKVNHGLVFRHFGTKDQLVGAVLD 71 TG E++ A I AA L AERG +T++R IA R+ V+ LV HFG+K V+D Sbjct 6 TGPEDLTAKARIRAAAFALVAERGVHSTTVRGIAQRAGVSPALVIHHFGSKQ----GVID 61 Query 72 HLGTKLTRLLHSEA--------PADIIERALDRHGRVLA----------RALLDGYPVG- 112 + T + LH PA ++R L R R++A R LLDG P G Sbjct 62 AISTWIVEYLHRNTREPDRGGDPAQALQRRLVRFERMVAEVPLLGAYVRRMLLDGQPDGL 121 Query 113 QLQQRFPNVA-------ELLDAVRPRYDSDLGARLAVAHALALQFGWRLFAPMLRSATGI 165 +R +++ E + RP D R A L F L PML A G+ Sbjct 122 DWFRRAVDLSAEELAHRERMGKARPSTD----LRAEAAMLFILGFAPVLLGPMLEHALGL 177 Query 166 D 166 D Sbjct 178 D 178 >gi|300784384|ref|YP_003764675.1| TetR family transcriptional regulator [Amycolatopsis mediterranei U32] gi|299793898|gb|ADJ44273.1| TetR family transcriptional regulator [Amycolatopsis mediterranei U32] gi|340525804|gb|AEK41009.1| TetR family transcriptional regulator [Amycolatopsis mediterranei S699] Length=205 Score = 55.5 bits (132), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 31/75 (42%), Positives = 42/75 (56%), Gaps = 0/75 (0%) Query 7 TDRRKMPTGREEVAAAILQAATDLFAERGPAATSIRDIAARSKVNHGLVFRHFGTKDQLV 66 T R RE+ A+L A D E G A TS+++I AR+ V+ G V HF K +L+ Sbjct 4 TTHRTQAQRREQTRTALLDATIDCLVEVGYARTSVQEICARAGVSKGAVQHHFTAKAELM 63 Query 67 GAVLDHLGTKLTRLL 81 A ++HL TKL R L Sbjct 64 AAAVEHLTTKLRRRL 78 Lambda K H 0.323 0.137 0.394 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 183812957610 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40