BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv3449 Length=455 Score E Sequences producing significant alignments: (Bits) Value gi|308232468|ref|ZP_07416133.2| membrane-anchored mycosin mycP4 ... 888 0.0 gi|15610585|ref|NP_217966.1| membrane-anchored mycosin [Mycobact... 888 0.0 gi|289449154|ref|ZP_06438898.1| membrane-anchored mycosin mycP4 ... 887 0.0 gi|289747283|ref|ZP_06506661.1| membrane-anchored mycosin mycP4 ... 886 0.0 gi|289755582|ref|ZP_06514960.1| serine protease [Mycobacterium t... 886 0.0 gi|289571683|ref|ZP_06451910.1| membrane-anchored mycosin mycP4 ... 885 0.0 gi|340628420|ref|YP_004746872.1| putative membrane-anchored myco... 873 0.0 gi|167967311|ref|ZP_02549588.1| membrane-anchored mycosin mycP4 ... 748 0.0 gi|289752174|ref|ZP_06511552.1| LOW QUALITY PROTEIN: membrane-an... 730 0.0 gi|289445050|ref|ZP_06434794.1| LOW QUALITY PROTEIN: secreted se... 664 0.0 gi|339299875|gb|AEJ51985.1| membrane-anchored mycosin mycP4 [Myc... 569 4e-160 gi|240167792|ref|ZP_04746451.1| putative secreted serine proteas... 567 1e-159 gi|183981120|ref|YP_001849411.1| membrane-anchored serine protea... 535 7e-150 gi|118616633|ref|YP_904965.1| membrane-anchored serine protease ... 532 6e-149 gi|254819227|ref|ZP_05224228.1| peptidase [Mycobacterium intrace... 512 5e-143 gi|342861876|ref|ZP_08718521.1| peptidase [Mycobacterium colombi... 508 1e-141 gi|254776824|ref|ZP_05218340.1| peptidase [Mycobacterium avium s... 506 5e-141 gi|118465498|ref|YP_883527.1| peptidase [Mycobacterium avium 104... 498 1e-138 gi|41410337|ref|NP_963173.1| hypothetical protein MAP4239c [Myco... 489 3e-136 gi|336460698|gb|EGO39588.1| type VII secretion-associated serine... 489 4e-136 gi|296168730|ref|ZP_06850440.1| serine protease [Mycobacterium p... 475 9e-132 gi|120402456|ref|YP_952285.1| peptidase S8/S53 subtilisin kexin ... 411 1e-112 gi|126433754|ref|YP_001069445.1| peptidase S8/S53 subtilisin kex... 387 2e-105 gi|108798096|ref|YP_638293.1| peptidase S8/S53 subtilisin kexin ... 384 2e-104 gi|145225537|ref|YP_001136215.1| peptidase S8/S53 subtilisin kex... 383 5e-104 gi|315445890|ref|YP_004078769.1| subtilisin-like serine protease... 377 2e-102 gi|169630837|ref|YP_001704486.1| putative protease [Mycobacteriu... 364 2e-98 gi|333991915|ref|YP_004524529.1| membrane-anchored serine protea... 352 8e-95 gi|118467437|ref|YP_885916.1| subtilase [Mycobacterium smegmatis... 344 1e-92 gi|226305378|ref|YP_002765336.1| S8 family peptidase [Rhodococcu... 329 7e-88 gi|229489382|ref|ZP_04383245.1| peptidase S8 and S53, subtilisin... 324 2e-86 gi|325675481|ref|ZP_08155165.1| serine protease [Rhodococcus equ... 323 4e-86 gi|312140881|ref|YP_004008217.1| esx cluster serine peptidase [R... 323 5e-86 gi|226365630|ref|YP_002783413.1| subtilisin family peptidase [Rh... 300 3e-79 gi|343925121|ref|ZP_08764653.1| putative S8 family peptidase [Go... 298 1e-78 gi|169629311|ref|YP_001702960.1| peptidase [Mycobacterium absces... 294 3e-77 gi|54022816|ref|YP_117058.1| putative protease [Nocardia farcini... 293 4e-77 gi|54022795|ref|YP_117037.1| putative protease [Nocardia farcini... 292 8e-77 gi|333921710|ref|YP_004495291.1| serine protease [Amycolicicoccu... 284 2e-74 gi|118469114|ref|YP_885035.1| subtilase [Mycobacterium smegmatis... 283 5e-74 gi|339299876|gb|AEJ51986.1| membrane-anchored mycosin mycP4 [Myc... 280 5e-73 gi|167967142|ref|ZP_02549419.1| membrane-anchored mycosin mycP3 ... 271 2e-70 gi|15607432|ref|NP_214805.1| membrane-anchored mycosin [Mycobact... 271 2e-70 gi|108797360|ref|YP_637557.1| peptidase S8/S53 subtilisin kexin ... 270 3e-70 gi|339293349|gb|AEJ45460.1| membrane-anchored mycosin mycP3 [Myc... 270 3e-70 gi|326381856|ref|ZP_08203549.1| peptidase S8/S53 subtilisin kexi... 270 3e-70 gi|298523762|ref|ZP_07011171.1| membrane-anchored mycosin [Mycob... 270 5e-70 gi|262201636|ref|YP_003272844.1| peptidase S8/S53 subtilisin kex... 268 2e-69 gi|254230665|ref|ZP_04923992.1| membrane-anchored mycosin mycP3 ... 268 2e-69 gi|15826894|ref|NP_301157.1| protease [Mycobacterium leprae TN] ... 267 2e-69 >gi|308232468|ref|ZP_07416133.2| membrane-anchored mycosin mycP4 [Mycobacterium tuberculosis SUMu001] gi|308370267|ref|ZP_07420852.2| membrane-anchored mycosin mycP4 [Mycobacterium tuberculosis SUMu002] gi|308371350|ref|ZP_07667144.1| membrane-anchored mycosin mycP4 [Mycobacterium tuberculosis SUMu003] 19 more sequence titles Length=457 Score = 888 bits (2295), Expect = 0.0, Method: Compositional matrix adjust. Identities = 455/455 (100%), Positives = 455/455 (100%), Gaps = 0/455 (0%) Query 1 MTTSRTLRLLVVSALATLSGLGTPVAHAVSPPPIDERWLPESALPAPPRPTVQREVCTEV 60 MTTSRTLRLLVVSALATLSGLGTPVAHAVSPPPIDERWLPESALPAPPRPTVQREVCTEV Sbjct 3 MTTSRTLRLLVVSALATLSGLGTPVAHAVSPPPIDERWLPESALPAPPRPTVQREVCTEV 62 Query 61 TAESGRAFGRAERSAQLADLDQVWRLTRGAGQRVAVIDTGVARHRRLPKVVAGGDYVFTG 120 TAESGRAFGRAERSAQLADLDQVWRLTRGAGQRVAVIDTGVARHRRLPKVVAGGDYVFTG Sbjct 63 TAESGRAFGRAERSAQLADLDQVWRLTRGAGQRVAVIDTGVARHRRLPKVVAGGDYVFTG 122 Query 121 DGTADCDAHGTLVAGIIAAAPDAQSDNFSGVAPDVTLISIRQSSSKFAPVGDPSSTGVGD 180 DGTADCDAHGTLVAGIIAAAPDAQSDNFSGVAPDVTLISIRQSSSKFAPVGDPSSTGVGD Sbjct 123 DGTADCDAHGTLVAGIIAAAPDAQSDNFSGVAPDVTLISIRQSSSKFAPVGDPSSTGVGD 182 Query 181 VDTMAKAVRTAADLGASVINISSIACVPAAAAPDDRALGAALAYAVDVKNAVIVAAAGNT 240 VDTMAKAVRTAADLGASVINISSIACVPAAAAPDDRALGAALAYAVDVKNAVIVAAAGNT Sbjct 183 VDTMAKAVRTAADLGASVINISSIACVPAAAAPDDRALGAALAYAVDVKNAVIVAAAGNT 242 Query 241 GGAAQCPPQAPGVTRDSVTVAVSPAWYDDYVLTVGSVNAQGEPSAFTLAGPWVDVAATGE 300 GGAAQCPPQAPGVTRDSVTVAVSPAWYDDYVLTVGSVNAQGEPSAFTLAGPWVDVAATGE Sbjct 243 GGAAQCPPQAPGVTRDSVTVAVSPAWYDDYVLTVGSVNAQGEPSAFTLAGPWVDVAATGE 302 Query 301 AVTSLSPFGDGTVNRLGGQHGSIPISGTSYAAPVVSGLAALIRARFPTLTARQVMQRIES 360 AVTSLSPFGDGTVNRLGGQHGSIPISGTSYAAPVVSGLAALIRARFPTLTARQVMQRIES Sbjct 303 AVTSLSPFGDGTVNRLGGQHGSIPISGTSYAAPVVSGLAALIRARFPTLTARQVMQRIES 362 Query 361 TAHHPPAGWDPLVGNGTVDALAAVSSDSIPQAGTATSDPAPVAVPVPRRSTPGPSDRRAL 420 TAHHPPAGWDPLVGNGTVDALAAVSSDSIPQAGTATSDPAPVAVPVPRRSTPGPSDRRAL Sbjct 363 TAHHPPAGWDPLVGNGTVDALAAVSSDSIPQAGTATSDPAPVAVPVPRRSTPGPSDRRAL 422 Query 421 HTAFAGAAICLLALMATLATASRRLRPGRNGIAGD 455 HTAFAGAAICLLALMATLATASRRLRPGRNGIAGD Sbjct 423 HTAFAGAAICLLALMATLATASRRLRPGRNGIAGD 457 >gi|15610585|ref|NP_217966.1| membrane-anchored mycosin [Mycobacterium tuberculosis H37Rv] gi|15843044|ref|NP_338081.1| serine protease [Mycobacterium tuberculosis CDC1551] gi|31794626|ref|NP_857119.1| secreted serine protease [Mycobacterium bovis AF2122/97] 33 more sequence titles Length=455 Score = 888 bits (2294), Expect = 0.0, Method: Compositional matrix adjust. Identities = 455/455 (100%), Positives = 455/455 (100%), Gaps = 0/455 (0%) Query 1 MTTSRTLRLLVVSALATLSGLGTPVAHAVSPPPIDERWLPESALPAPPRPTVQREVCTEV 60 MTTSRTLRLLVVSALATLSGLGTPVAHAVSPPPIDERWLPESALPAPPRPTVQREVCTEV Sbjct 1 MTTSRTLRLLVVSALATLSGLGTPVAHAVSPPPIDERWLPESALPAPPRPTVQREVCTEV 60 Query 61 TAESGRAFGRAERSAQLADLDQVWRLTRGAGQRVAVIDTGVARHRRLPKVVAGGDYVFTG 120 TAESGRAFGRAERSAQLADLDQVWRLTRGAGQRVAVIDTGVARHRRLPKVVAGGDYVFTG Sbjct 61 TAESGRAFGRAERSAQLADLDQVWRLTRGAGQRVAVIDTGVARHRRLPKVVAGGDYVFTG 120 Query 121 DGTADCDAHGTLVAGIIAAAPDAQSDNFSGVAPDVTLISIRQSSSKFAPVGDPSSTGVGD 180 DGTADCDAHGTLVAGIIAAAPDAQSDNFSGVAPDVTLISIRQSSSKFAPVGDPSSTGVGD Sbjct 121 DGTADCDAHGTLVAGIIAAAPDAQSDNFSGVAPDVTLISIRQSSSKFAPVGDPSSTGVGD 180 Query 181 VDTMAKAVRTAADLGASVINISSIACVPAAAAPDDRALGAALAYAVDVKNAVIVAAAGNT 240 VDTMAKAVRTAADLGASVINISSIACVPAAAAPDDRALGAALAYAVDVKNAVIVAAAGNT Sbjct 181 VDTMAKAVRTAADLGASVINISSIACVPAAAAPDDRALGAALAYAVDVKNAVIVAAAGNT 240 Query 241 GGAAQCPPQAPGVTRDSVTVAVSPAWYDDYVLTVGSVNAQGEPSAFTLAGPWVDVAATGE 300 GGAAQCPPQAPGVTRDSVTVAVSPAWYDDYVLTVGSVNAQGEPSAFTLAGPWVDVAATGE Sbjct 241 GGAAQCPPQAPGVTRDSVTVAVSPAWYDDYVLTVGSVNAQGEPSAFTLAGPWVDVAATGE 300 Query 301 AVTSLSPFGDGTVNRLGGQHGSIPISGTSYAAPVVSGLAALIRARFPTLTARQVMQRIES 360 AVTSLSPFGDGTVNRLGGQHGSIPISGTSYAAPVVSGLAALIRARFPTLTARQVMQRIES Sbjct 301 AVTSLSPFGDGTVNRLGGQHGSIPISGTSYAAPVVSGLAALIRARFPTLTARQVMQRIES 360 Query 361 TAHHPPAGWDPLVGNGTVDALAAVSSDSIPQAGTATSDPAPVAVPVPRRSTPGPSDRRAL 420 TAHHPPAGWDPLVGNGTVDALAAVSSDSIPQAGTATSDPAPVAVPVPRRSTPGPSDRRAL Sbjct 361 TAHHPPAGWDPLVGNGTVDALAAVSSDSIPQAGTATSDPAPVAVPVPRRSTPGPSDRRAL 420 Query 421 HTAFAGAAICLLALMATLATASRRLRPGRNGIAGD 455 HTAFAGAAICLLALMATLATASRRLRPGRNGIAGD Sbjct 421 HTAFAGAAICLLALMATLATASRRLRPGRNGIAGD 455 >gi|289449154|ref|ZP_06438898.1| membrane-anchored mycosin mycP4 [Mycobacterium tuberculosis CPHL_A] gi|289422112|gb|EFD19313.1| membrane-anchored mycosin mycP4 [Mycobacterium tuberculosis CPHL_A] Length=455 Score = 887 bits (2291), Expect = 0.0, Method: Compositional matrix adjust. Identities = 454/455 (99%), Positives = 455/455 (100%), Gaps = 0/455 (0%) Query 1 MTTSRTLRLLVVSALATLSGLGTPVAHAVSPPPIDERWLPESALPAPPRPTVQREVCTEV 60 MTTSRTLRLLVVSALATLSGLGTPVAHAVSPPPIDERWLPESALPAPPRPTVQREVCTEV Sbjct 1 MTTSRTLRLLVVSALATLSGLGTPVAHAVSPPPIDERWLPESALPAPPRPTVQREVCTEV 60 Query 61 TAESGRAFGRAERSAQLADLDQVWRLTRGAGQRVAVIDTGVARHRRLPKVVAGGDYVFTG 120 TAESGRAFGRAERSAQLADLDQVWRLTRGAGQRVAVIDTGVARHRRLPKVVAGGDYVFTG Sbjct 61 TAESGRAFGRAERSAQLADLDQVWRLTRGAGQRVAVIDTGVARHRRLPKVVAGGDYVFTG 120 Query 121 DGTADCDAHGTLVAGIIAAAPDAQSDNFSGVAPDVTLISIRQSSSKFAPVGDPSSTGVGD 180 DGTADCDAHGTLVAGIIAAAPDAQSDNFSGVAPDVTLISIRQ+SSKFAPVGDPSSTGVGD Sbjct 121 DGTADCDAHGTLVAGIIAAAPDAQSDNFSGVAPDVTLISIRQASSKFAPVGDPSSTGVGD 180 Query 181 VDTMAKAVRTAADLGASVINISSIACVPAAAAPDDRALGAALAYAVDVKNAVIVAAAGNT 240 VDTMAKAVRTAADLGASVINISSIACVPAAAAPDDRALGAALAYAVDVKNAVIVAAAGNT Sbjct 181 VDTMAKAVRTAADLGASVINISSIACVPAAAAPDDRALGAALAYAVDVKNAVIVAAAGNT 240 Query 241 GGAAQCPPQAPGVTRDSVTVAVSPAWYDDYVLTVGSVNAQGEPSAFTLAGPWVDVAATGE 300 GGAAQCPPQAPGVTRDSVTVAVSPAWYDDYVLTVGSVNAQGEPSAFTLAGPWVDVAATGE Sbjct 241 GGAAQCPPQAPGVTRDSVTVAVSPAWYDDYVLTVGSVNAQGEPSAFTLAGPWVDVAATGE 300 Query 301 AVTSLSPFGDGTVNRLGGQHGSIPISGTSYAAPVVSGLAALIRARFPTLTARQVMQRIES 360 AVTSLSPFGDGTVNRLGGQHGSIPISGTSYAAPVVSGLAALIRARFPTLTARQVMQRIES Sbjct 301 AVTSLSPFGDGTVNRLGGQHGSIPISGTSYAAPVVSGLAALIRARFPTLTARQVMQRIES 360 Query 361 TAHHPPAGWDPLVGNGTVDALAAVSSDSIPQAGTATSDPAPVAVPVPRRSTPGPSDRRAL 420 TAHHPPAGWDPLVGNGTVDALAAVSSDSIPQAGTATSDPAPVAVPVPRRSTPGPSDRRAL Sbjct 361 TAHHPPAGWDPLVGNGTVDALAAVSSDSIPQAGTATSDPAPVAVPVPRRSTPGPSDRRAL 420 Query 421 HTAFAGAAICLLALMATLATASRRLRPGRNGIAGD 455 HTAFAGAAICLLALMATLATASRRLRPGRNGIAGD Sbjct 421 HTAFAGAAICLLALMATLATASRRLRPGRNGIAGD 455 >gi|289747283|ref|ZP_06506661.1| membrane-anchored mycosin mycP4 [Mycobacterium tuberculosis 02_1987] gi|289759612|ref|ZP_06518990.1| membrane-anchored mycosin MycP4 [Mycobacterium tuberculosis T85] gi|294995770|ref|ZP_06801461.1| membrane-anchored mycosin mycP4 [Mycobacterium tuberculosis 210] 6 more sequence titles Length=455 Score = 886 bits (2289), Expect = 0.0, Method: Compositional matrix adjust. Identities = 454/455 (99%), Positives = 454/455 (99%), Gaps = 0/455 (0%) Query 1 MTTSRTLRLLVVSALATLSGLGTPVAHAVSPPPIDERWLPESALPAPPRPTVQREVCTEV 60 MTTSRTLRLLVVSALATLSGLGTPVAHAVSPPPIDERWLPESALPAPPRPTVQREVCTEV Sbjct 1 MTTSRTLRLLVVSALATLSGLGTPVAHAVSPPPIDERWLPESALPAPPRPTVQREVCTEV 60 Query 61 TAESGRAFGRAERSAQLADLDQVWRLTRGAGQRVAVIDTGVARHRRLPKVVAGGDYVFTG 120 TAESGRAFGRAERSAQLADLDQVWRL RGAGQRVAVIDTGVARHRRLPKVVAGGDYVFTG Sbjct 61 TAESGRAFGRAERSAQLADLDQVWRLARGAGQRVAVIDTGVARHRRLPKVVAGGDYVFTG 120 Query 121 DGTADCDAHGTLVAGIIAAAPDAQSDNFSGVAPDVTLISIRQSSSKFAPVGDPSSTGVGD 180 DGTADCDAHGTLVAGIIAAAPDAQSDNFSGVAPDVTLISIRQSSSKFAPVGDPSSTGVGD Sbjct 121 DGTADCDAHGTLVAGIIAAAPDAQSDNFSGVAPDVTLISIRQSSSKFAPVGDPSSTGVGD 180 Query 181 VDTMAKAVRTAADLGASVINISSIACVPAAAAPDDRALGAALAYAVDVKNAVIVAAAGNT 240 VDTMAKAVRTAADLGASVINISSIACVPAAAAPDDRALGAALAYAVDVKNAVIVAAAGNT Sbjct 181 VDTMAKAVRTAADLGASVINISSIACVPAAAAPDDRALGAALAYAVDVKNAVIVAAAGNT 240 Query 241 GGAAQCPPQAPGVTRDSVTVAVSPAWYDDYVLTVGSVNAQGEPSAFTLAGPWVDVAATGE 300 GGAAQCPPQAPGVTRDSVTVAVSPAWYDDYVLTVGSVNAQGEPSAFTLAGPWVDVAATGE Sbjct 241 GGAAQCPPQAPGVTRDSVTVAVSPAWYDDYVLTVGSVNAQGEPSAFTLAGPWVDVAATGE 300 Query 301 AVTSLSPFGDGTVNRLGGQHGSIPISGTSYAAPVVSGLAALIRARFPTLTARQVMQRIES 360 AVTSLSPFGDGTVNRLGGQHGSIPISGTSYAAPVVSGLAALIRARFPTLTARQVMQRIES Sbjct 301 AVTSLSPFGDGTVNRLGGQHGSIPISGTSYAAPVVSGLAALIRARFPTLTARQVMQRIES 360 Query 361 TAHHPPAGWDPLVGNGTVDALAAVSSDSIPQAGTATSDPAPVAVPVPRRSTPGPSDRRAL 420 TAHHPPAGWDPLVGNGTVDALAAVSSDSIPQAGTATSDPAPVAVPVPRRSTPGPSDRRAL Sbjct 361 TAHHPPAGWDPLVGNGTVDALAAVSSDSIPQAGTATSDPAPVAVPVPRRSTPGPSDRRAL 420 Query 421 HTAFAGAAICLLALMATLATASRRLRPGRNGIAGD 455 HTAFAGAAICLLALMATLATASRRLRPGRNGIAGD Sbjct 421 HTAFAGAAICLLALMATLATASRRLRPGRNGIAGD 455 >gi|289755582|ref|ZP_06514960.1| serine protease [Mycobacterium tuberculosis EAS054] gi|289696169|gb|EFD63598.1| serine protease [Mycobacterium tuberculosis EAS054] Length=455 Score = 886 bits (2289), Expect = 0.0, Method: Compositional matrix adjust. Identities = 454/455 (99%), Positives = 454/455 (99%), Gaps = 0/455 (0%) Query 1 MTTSRTLRLLVVSALATLSGLGTPVAHAVSPPPIDERWLPESALPAPPRPTVQREVCTEV 60 MTTSRTLRLLVVSALATLSGLGTPVAHAVSPPPIDERWLPESALPAPPRPTVQREVCTEV Sbjct 1 MTTSRTLRLLVVSALATLSGLGTPVAHAVSPPPIDERWLPESALPAPPRPTVQREVCTEV 60 Query 61 TAESGRAFGRAERSAQLADLDQVWRLTRGAGQRVAVIDTGVARHRRLPKVVAGGDYVFTG 120 TAESGRAFGRAERSAQLADLDQVWRLTRGAGQRVAVIDTGVARHRRLPKVVAGGDYVFTG Sbjct 61 TAESGRAFGRAERSAQLADLDQVWRLTRGAGQRVAVIDTGVARHRRLPKVVAGGDYVFTG 120 Query 121 DGTADCDAHGTLVAGIIAAAPDAQSDNFSGVAPDVTLISIRQSSSKFAPVGDPSSTGVGD 180 DGTADCDAHGTLVAGIIAAAPDAQSDNFSGVAPDVTLISIRQSSSKFAPVGDPSSTGVGD Sbjct 121 DGTADCDAHGTLVAGIIAAAPDAQSDNFSGVAPDVTLISIRQSSSKFAPVGDPSSTGVGD 180 Query 181 VDTMAKAVRTAADLGASVINISSIACVPAAAAPDDRALGAALAYAVDVKNAVIVAAAGNT 240 VDTMAKAVRTAADLGASVINISSIACVPAAAAPDDRALGAALAYAVDVKNAVIVAAAGNT Sbjct 181 VDTMAKAVRTAADLGASVINISSIACVPAAAAPDDRALGAALAYAVDVKNAVIVAAAGNT 240 Query 241 GGAAQCPPQAPGVTRDSVTVAVSPAWYDDYVLTVGSVNAQGEPSAFTLAGPWVDVAATGE 300 GGAAQCPPQAPGVTRDSVTVAVSPAWYDDYVLTVGSVNAQGEPSAFTLAGPWVDVAATGE Sbjct 241 GGAAQCPPQAPGVTRDSVTVAVSPAWYDDYVLTVGSVNAQGEPSAFTLAGPWVDVAATGE 300 Query 301 AVTSLSPFGDGTVNRLGGQHGSIPISGTSYAAPVVSGLAALIRARFPTLTARQVMQRIES 360 AVTSLSPFGDGTVNRLGGQHGSIPISGTSYAAPVVSGLAALIRARFPTLTARQVMQRIES Sbjct 301 AVTSLSPFGDGTVNRLGGQHGSIPISGTSYAAPVVSGLAALIRARFPTLTARQVMQRIES 360 Query 361 TAHHPPAGWDPLVGNGTVDALAAVSSDSIPQAGTATSDPAPVAVPVPRRSTPGPSDRRAL 420 TAHHPPAGWDPLVGNGTVDALAAVSSDSIPQAGTATSDPAPVAVPVPRRSTPG SDRRAL Sbjct 361 TAHHPPAGWDPLVGNGTVDALAAVSSDSIPQAGTATSDPAPVAVPVPRRSTPGSSDRRAL 420 Query 421 HTAFAGAAICLLALMATLATASRRLRPGRNGIAGD 455 HTAFAGAAICLLALMATLATASRRLRPGRNGIAGD Sbjct 421 HTAFAGAAICLLALMATLATASRRLRPGRNGIAGD 455 >gi|289571683|ref|ZP_06451910.1| membrane-anchored mycosin mycP4 [Mycobacterium tuberculosis T17] gi|289545437|gb|EFD49085.1| membrane-anchored mycosin mycP4 [Mycobacterium tuberculosis T17] Length=455 Score = 885 bits (2286), Expect = 0.0, Method: Compositional matrix adjust. Identities = 454/455 (99%), Positives = 454/455 (99%), Gaps = 0/455 (0%) Query 1 MTTSRTLRLLVVSALATLSGLGTPVAHAVSPPPIDERWLPESALPAPPRPTVQREVCTEV 60 MTTSRTLRLLVVSALATLSGLGTPVAHAVSPPPIDERWLPESALPAPPRPTVQREVCTEV Sbjct 1 MTTSRTLRLLVVSALATLSGLGTPVAHAVSPPPIDERWLPESALPAPPRPTVQREVCTEV 60 Query 61 TAESGRAFGRAERSAQLADLDQVWRLTRGAGQRVAVIDTGVARHRRLPKVVAGGDYVFTG 120 TAESGRAFGRAERSAQLADLDQVWRLTRGAGQRVAVIDTGVARHRRLPKVVAGGDYVFTG Sbjct 61 TAESGRAFGRAERSAQLADLDQVWRLTRGAGQRVAVIDTGVARHRRLPKVVAGGDYVFTG 120 Query 121 DGTADCDAHGTLVAGIIAAAPDAQSDNFSGVAPDVTLISIRQSSSKFAPVGDPSSTGVGD 180 DGTADCDAHGTLVAGIIAAAPDAQSDNFSGVAPDVTLISIRQSSSKFAPVGDPSSTGVGD Sbjct 121 DGTADCDAHGTLVAGIIAAAPDAQSDNFSGVAPDVTLISIRQSSSKFAPVGDPSSTGVGD 180 Query 181 VDTMAKAVRTAADLGASVINISSIACVPAAAAPDDRALGAALAYAVDVKNAVIVAAAGNT 240 VDTMAKAVRTAADLGASVINISSIACVPAAAAPDDRALGAALAYAVDVKNAVIVAAAGNT Sbjct 181 VDTMAKAVRTAADLGASVINISSIACVPAAAAPDDRALGAALAYAVDVKNAVIVAAAGNT 240 Query 241 GGAAQCPPQAPGVTRDSVTVAVSPAWYDDYVLTVGSVNAQGEPSAFTLAGPWVDVAATGE 300 GGAAQCPPQAPGVTRDSVTVAVSPAWYDDYVLTVGSVNAQGEPSAFTLAGPWVDVAATGE Sbjct 241 GGAAQCPPQAPGVTRDSVTVAVSPAWYDDYVLTVGSVNAQGEPSAFTLAGPWVDVAATGE 300 Query 301 AVTSLSPFGDGTVNRLGGQHGSIPISGTSYAAPVVSGLAALIRARFPTLTARQVMQRIES 360 AVTSLSPFGDGTVNRLGGQHGSIPISGTSYAAPVVSGLAALIRARFPTLTARQVMQRIES Sbjct 301 AVTSLSPFGDGTVNRLGGQHGSIPISGTSYAAPVVSGLAALIRARFPTLTARQVMQRIES 360 Query 361 TAHHPPAGWDPLVGNGTVDALAAVSSDSIPQAGTATSDPAPVAVPVPRRSTPGPSDRRAL 420 TAHHPPAGWDPLVGNGTVDALAAVSSDSIPQAGTATSDPAPVAVPVPRRSTPGPSDRRAL Sbjct 361 TAHHPPAGWDPLVGNGTVDALAAVSSDSIPQAGTATSDPAPVAVPVPRRSTPGPSDRRAL 420 Query 421 HTAFAGAAICLLALMATLATASRRLRPGRNGIAGD 455 HTAFAGAAICLLALMATLATASRRLRP RNGIAGD Sbjct 421 HTAFAGAAICLLALMATLATASRRLRPRRNGIAGD 455 >gi|340628420|ref|YP_004746872.1| putative membrane-anchored mycosin MYCP4 [Mycobacterium canettii CIPT 140010059] gi|340006610|emb|CCC45797.1| putative membrane-anchored mycosin MYCP4 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-4) [Mycobacterium canettii CIPT 140010059] Length=455 Score = 873 bits (2256), Expect = 0.0, Method: Compositional matrix adjust. Identities = 449/455 (99%), Positives = 450/455 (99%), Gaps = 0/455 (0%) Query 1 MTTSRTLRLLVVSALATLSGLGTPVAHAVSPPPIDERWLPESALPAPPRPTVQREVCTEV 60 MTTSRTLRLLVVSALATLSGLGTPVAHAVSPPPIDERWLPESALPAPPRPTVQREVCTEV Sbjct 1 MTTSRTLRLLVVSALATLSGLGTPVAHAVSPPPIDERWLPESALPAPPRPTVQREVCTEV 60 Query 61 TAESGRAFGRAERSAQLADLDQVWRLTRGAGQRVAVIDTGVARHRRLPKVVAGGDYVFTG 120 TAESGRAFGRAE AQLADLDQVWRLTRGAGQRVAVIDTGVARHRRLPKVVAGGDYVFTG Sbjct 61 TAESGRAFGRAEPPAQLADLDQVWRLTRGAGQRVAVIDTGVARHRRLPKVVAGGDYVFTG 120 Query 121 DGTADCDAHGTLVAGIIAAAPDAQSDNFSGVAPDVTLISIRQSSSKFAPVGDPSSTGVGD 180 DGTADCDAHGTLVAGIIAAAPDAQSDNFSGVAPDVTLISIRQSSSKFAPVGDPSSTGVGD Sbjct 121 DGTADCDAHGTLVAGIIAAAPDAQSDNFSGVAPDVTLISIRQSSSKFAPVGDPSSTGVGD 180 Query 181 VDTMAKAVRTAADLGASVINISSIACVPAAAAPDDRALGAALAYAVDVKNAVIVAAAGNT 240 VDTMAKAVRTAADLGASVINISSIACVPAAAAPDDRALGAALAYAVDVKNAVIVAAAGNT Sbjct 181 VDTMAKAVRTAADLGASVINISSIACVPAAAAPDDRALGAALAYAVDVKNAVIVAAAGNT 240 Query 241 GGAAQCPPQAPGVTRDSVTVAVSPAWYDDYVLTVGSVNAQGEPSAFTLAGPWVDVAATGE 300 GGAAQCPPQAPGVTRDSVTVAVSPAWYDDYVLTVGSVNAQGEPSAFTLAGPWVDVAATGE Sbjct 241 GGAAQCPPQAPGVTRDSVTVAVSPAWYDDYVLTVGSVNAQGEPSAFTLAGPWVDVAATGE 300 Query 301 AVTSLSPFGDGTVNRLGGQHGSIPISGTSYAAPVVSGLAALIRARFPTLTARQVMQRIES 360 AVTSL PFGDGTVNRLGGQHGS PISGTSYAAPVVSGLAALIRARFPT TARQVMQRIES Sbjct 301 AVTSLGPFGDGTVNRLGGQHGSTPISGTSYAAPVVSGLAALIRARFPTWTARQVMQRIES 360 Query 361 TAHHPPAGWDPLVGNGTVDALAAVSSDSIPQAGTATSDPAPVAVPVPRRSTPGPSDRRAL 420 TAHHPPAGWDPLVGNGTVDALAAVSSDSIPQAG+ATSDPAPVAVPVPRRSTPGPSDRRAL Sbjct 361 TAHHPPAGWDPLVGNGTVDALAAVSSDSIPQAGSATSDPAPVAVPVPRRSTPGPSDRRAL 420 Query 421 HTAFAGAAICLLALMATLATASRRLRPGRNGIAGD 455 HTAFAGAAICLLALMATLATASRRLRPGRNGIAGD Sbjct 421 HTAFAGAAICLLALMATLATASRRLRPGRNGIAGD 455 >gi|167967311|ref|ZP_02549588.1| membrane-anchored mycosin mycP4 [Mycobacterium tuberculosis H37Ra] Length=409 Score = 748 bits (1930), Expect = 0.0, Method: Compositional matrix adjust. Identities = 381/381 (100%), Positives = 381/381 (100%), Gaps = 0/381 (0%) Query 1 MTTSRTLRLLVVSALATLSGLGTPVAHAVSPPPIDERWLPESALPAPPRPTVQREVCTEV 60 MTTSRTLRLLVVSALATLSGLGTPVAHAVSPPPIDERWLPESALPAPPRPTVQREVCTEV Sbjct 3 MTTSRTLRLLVVSALATLSGLGTPVAHAVSPPPIDERWLPESALPAPPRPTVQREVCTEV 62 Query 61 TAESGRAFGRAERSAQLADLDQVWRLTRGAGQRVAVIDTGVARHRRLPKVVAGGDYVFTG 120 TAESGRAFGRAERSAQLADLDQVWRLTRGAGQRVAVIDTGVARHRRLPKVVAGGDYVFTG Sbjct 63 TAESGRAFGRAERSAQLADLDQVWRLTRGAGQRVAVIDTGVARHRRLPKVVAGGDYVFTG 122 Query 121 DGTADCDAHGTLVAGIIAAAPDAQSDNFSGVAPDVTLISIRQSSSKFAPVGDPSSTGVGD 180 DGTADCDAHGTLVAGIIAAAPDAQSDNFSGVAPDVTLISIRQSSSKFAPVGDPSSTGVGD Sbjct 123 DGTADCDAHGTLVAGIIAAAPDAQSDNFSGVAPDVTLISIRQSSSKFAPVGDPSSTGVGD 182 Query 181 VDTMAKAVRTAADLGASVINISSIACVPAAAAPDDRALGAALAYAVDVKNAVIVAAAGNT 240 VDTMAKAVRTAADLGASVINISSIACVPAAAAPDDRALGAALAYAVDVKNAVIVAAAGNT Sbjct 183 VDTMAKAVRTAADLGASVINISSIACVPAAAAPDDRALGAALAYAVDVKNAVIVAAAGNT 242 Query 241 GGAAQCPPQAPGVTRDSVTVAVSPAWYDDYVLTVGSVNAQGEPSAFTLAGPWVDVAATGE 300 GGAAQCPPQAPGVTRDSVTVAVSPAWYDDYVLTVGSVNAQGEPSAFTLAGPWVDVAATGE Sbjct 243 GGAAQCPPQAPGVTRDSVTVAVSPAWYDDYVLTVGSVNAQGEPSAFTLAGPWVDVAATGE 302 Query 301 AVTSLSPFGDGTVNRLGGQHGSIPISGTSYAAPVVSGLAALIRARFPTLTARQVMQRIES 360 AVTSLSPFGDGTVNRLGGQHGSIPISGTSYAAPVVSGLAALIRARFPTLTARQVMQRIES Sbjct 303 AVTSLSPFGDGTVNRLGGQHGSIPISGTSYAAPVVSGLAALIRARFPTLTARQVMQRIES 362 Query 361 TAHHPPAGWDPLVGNGTVDAL 381 TAHHPPAGWDPLVGNGTVDAL Sbjct 363 TAHHPPAGWDPLVGNGTVDAL 383 >gi|289752174|ref|ZP_06511552.1| LOW QUALITY PROTEIN: membrane-anchored mycosin mycP4 [Mycobacterium tuberculosis T92] gi|289692761|gb|EFD60190.1| LOW QUALITY PROTEIN: membrane-anchored mycosin mycP4 [Mycobacterium tuberculosis T92] Length=414 Score = 730 bits (1885), Expect = 0.0, Method: Compositional matrix adjust. Identities = 400/410 (98%), Positives = 400/410 (98%), Gaps = 1/410 (0%) Query 47 PPRPTVQREVCTEVTAESGRAFGR-AERSAQLADLDQVWRLTRGAGQRVAVIDTGVARHR 105 PPRPTVQREVCTEVT G AERSAQLADLDQVWRLTRGAGQRVAVIDTGVARHR Sbjct 5 PPRPTVQREVCTEVTRRIGDGLSAGAERSAQLADLDQVWRLTRGAGQRVAVIDTGVARHR 64 Query 106 RLPKVVAGGDYVFTGDGTADCDAHGTLVAGIIAAAPDAQSDNFSGVAPDVTLISIRQSSS 165 RLPKVVAGGDYVFTGDGTADCDAHGTLVAGIIAAAPDAQSDNFSGVAPDVTLISIRQSSS Sbjct 65 RLPKVVAGGDYVFTGDGTADCDAHGTLVAGIIAAAPDAQSDNFSGVAPDVTLISIRQSSS 124 Query 166 KFAPVGDPSSTGVGDVDTMAKAVRTAADLGASVINISSIACVPAAAAPDDRALGAALAYA 225 KFAPVGDPSSTGVGDVDTMAKAVRTAADLGASVINISSIACVPAAAAPDDRALGAALAYA Sbjct 125 KFAPVGDPSSTGVGDVDTMAKAVRTAADLGASVINISSIACVPAAAAPDDRALGAALAYA 184 Query 226 VDVKNAVIVAAAGNTGGAAQCPPQAPGVTRDSVTVAVSPAWYDDYVLTVGSVNAQGEPSA 285 VDVKNAVIVAAAGNTGGAAQCPPQAPGVTRDSVTVAVSPAWYDDYVLTVGSVNAQGEPSA Sbjct 185 VDVKNAVIVAAAGNTGGAAQCPPQAPGVTRDSVTVAVSPAWYDDYVLTVGSVNAQGEPSA 244 Query 286 FTLAGPWVDVAATGEAVTSLSPFGDGTVNRLGGQHGSIPISGTSYAAPVVSGLAALIRAR 345 FTLAGPWVDVAATGEAVTSLSPFGDGTVNRLGGQHGSIPISGTSYAAPVVSGLAALIRAR Sbjct 245 FTLAGPWVDVAATGEAVTSLSPFGDGTVNRLGGQHGSIPISGTSYAAPVVSGLAALIRAR 304 Query 346 FPTLTARQVMQRIESTAHHPPAGWDPLVGNGTVDALAAVSSDSIPQAGTATSDPAPVAVP 405 FPTLTARQVMQRIESTAHHPPAGWDPLVGNGTVDALAAVSSDSIPQAGTATSDPAPVAVP Sbjct 305 FPTLTARQVMQRIESTAHHPPAGWDPLVGNGTVDALAAVSSDSIPQAGTATSDPAPVAVP 364 Query 406 VPRRSTPGPSDRRALHTAFAGAAICLLALMATLATASRRLRPGRNGIAGD 455 VPRRSTPGPSDRRALHTAFAGAAICLLALMATLATASRRLRP RNGIAGD Sbjct 365 VPRRSTPGPSDRRALHTAFAGAAICLLALMATLATASRRLRPRRNGIAGD 414 >gi|289445050|ref|ZP_06434794.1| LOW QUALITY PROTEIN: secreted serine protease [Mycobacterium tuberculosis T46] gi|289417969|gb|EFD15209.1| LOW QUALITY PROTEIN: secreted serine protease [Mycobacterium tuberculosis T46] Length=344 Score = 664 bits (1713), Expect = 0.0, Method: Compositional matrix adjust. Identities = 342/343 (99%), Positives = 342/343 (99%), Gaps = 0/343 (0%) Query 113 GGDYVFTGDGTADCDAHGTLVAGIIAAAPDAQSDNFSGVAPDVTLISIRQSSSKFAPVGD 172 GGDYVFTGDGTADCDAHGTLVAGIIAAAPDAQSDNFSGVAPDVTLISIRQSSSKFAPVGD Sbjct 2 GGDYVFTGDGTADCDAHGTLVAGIIAAAPDAQSDNFSGVAPDVTLISIRQSSSKFAPVGD 61 Query 173 PSSTGVGDVDTMAKAVRTAADLGASVINISSIACVPAAAAPDDRALGAALAYAVDVKNAV 232 PSSTGVGDVDTMAKAVRTAADLGASVINISSIACVPAAAAPDDRALGAALAYAVDVKNAV Sbjct 62 PSSTGVGDVDTMAKAVRTAADLGASVINISSIACVPAAAAPDDRALGAALAYAVDVKNAV 121 Query 233 IVAAAGNTGGAAQCPPQAPGVTRDSVTVAVSPAWYDDYVLTVGSVNAQGEPSAFTLAGPW 292 IVAAAGNTGGAAQCPPQAPGVTRDSVTVAVSPAWYDDYVLTVGSVNAQGEPSAFTLAGPW Sbjct 122 IVAAAGNTGGAAQCPPQAPGVTRDSVTVAVSPAWYDDYVLTVGSVNAQGEPSAFTLAGPW 181 Query 293 VDVAATGEAVTSLSPFGDGTVNRLGGQHGSIPISGTSYAAPVVSGLAALIRARFPTLTAR 352 VDVAATGEAVTSLSPFGDGTVNRLGGQHGSIPISGTSYAAPVVSGLAALIRARFPTLTAR Sbjct 182 VDVAATGEAVTSLSPFGDGTVNRLGGQHGSIPISGTSYAAPVVSGLAALIRARFPTLTAR 241 Query 353 QVMQRIESTAHHPPAGWDPLVGNGTVDALAAVSSDSIPQAGTATSDPAPVAVPVPRRSTP 412 QVMQRIESTAHHPPAGWDPLVGNGTVDALAAVSSDSIPQAGTATSDPAPVAVPVPRRSTP Sbjct 242 QVMQRIESTAHHPPAGWDPLVGNGTVDALAAVSSDSIPQAGTATSDPAPVAVPVPRRSTP 301 Query 413 GPSDRRALHTAFAGAAICLLALMATLATASRRLRPGRNGIAGD 455 GPSDRRALHTAFAGAAICLLALMATLATASRRLRP RNGIAGD Sbjct 302 GPSDRRALHTAFAGAAICLLALMATLATASRRLRPRRNGIAGD 344 >gi|339299875|gb|AEJ51985.1| membrane-anchored mycosin mycP4 [Mycobacterium tuberculosis CCDC5180] Length=309 Score = 569 bits (1466), Expect = 4e-160, Method: Compositional matrix adjust. Identities = 291/292 (99%), Positives = 291/292 (99%), Gaps = 0/292 (0%) Query 1 MTTSRTLRLLVVSALATLSGLGTPVAHAVSPPPIDERWLPESALPAPPRPTVQREVCTEV 60 MTTSRTLRLLVVSALATLSGLGTPVAHAVSPPPIDERWLPESALPAPPRPTVQREVCTEV Sbjct 1 MTTSRTLRLLVVSALATLSGLGTPVAHAVSPPPIDERWLPESALPAPPRPTVQREVCTEV 60 Query 61 TAESGRAFGRAERSAQLADLDQVWRLTRGAGQRVAVIDTGVARHRRLPKVVAGGDYVFTG 120 TAESGRAFGRAERSAQLADLDQVWRL RGAGQRVAVIDTGVARHRRLPKVVAGGDYVFTG Sbjct 61 TAESGRAFGRAERSAQLADLDQVWRLARGAGQRVAVIDTGVARHRRLPKVVAGGDYVFTG 120 Query 121 DGTADCDAHGTLVAGIIAAAPDAQSDNFSGVAPDVTLISIRQSSSKFAPVGDPSSTGVGD 180 DGTADCDAHGTLVAGIIAAAPDAQSDNFSGVAPDVTLISIRQSSSKFAPVGDPSSTGVGD Sbjct 121 DGTADCDAHGTLVAGIIAAAPDAQSDNFSGVAPDVTLISIRQSSSKFAPVGDPSSTGVGD 180 Query 181 VDTMAKAVRTAADLGASVINISSIACVPAAAAPDDRALGAALAYAVDVKNAVIVAAAGNT 240 VDTMAKAVRTAADLGASVINISSIACVPAAAAPDDRALGAALAYAVDVKNAVIVAAAGNT Sbjct 181 VDTMAKAVRTAADLGASVINISSIACVPAAAAPDDRALGAALAYAVDVKNAVIVAAAGNT 240 Query 241 GGAAQCPPQAPGVTRDSVTVAVSPAWYDDYVLTVGSVNAQGEPSAFTLAGPW 292 GGAAQCPPQAPGVTRDSVTVAVSPAWYDDYVLTVGSVNAQGEPSAFTLAGPW Sbjct 241 GGAAQCPPQAPGVTRDSVTVAVSPAWYDDYVLTVGSVNAQGEPSAFTLAGPW 292 >gi|240167792|ref|ZP_04746451.1| putative secreted serine protease [Mycobacterium kansasii ATCC 12478] Length=456 Score = 567 bits (1461), Expect = 1e-159, Method: Compositional matrix adjust. Identities = 319/458 (70%), Positives = 358/458 (79%), Gaps = 14/458 (3%) Query 6 TLRL--LVVSALATLSGLGTPVAHAVSPPPIDERWLPESALPAPPRPTVQREVCTEVTAE 63 T+RL L+V+AL TP AHAVSPP +DE+WLP + PAPPRPTVQREVCT TA Sbjct 5 TVRLAHLLVAALTMAPLWMTPPAHAVSPPRVDEKWLPAATSPAPPRPTVQREVCTGATAV 64 Query 64 SGRAFGRAERSAQLADLD--QVWRLTRGAGQRVAVIDTGVARHRRLPKVVAGGDYVFTGD 121 GR +AQLADL+ Q+W+LTRGAGQRVAVIDTGVARHRRLP +V GGDYV TGD Sbjct 65 PGRDGA----AAQLADLELPQLWQLTRGAGQRVAVIDTGVARHRRLPHLVGGGDYVSTGD 120 Query 122 GTADCDAHGTLVAGIIAAAPDAQSDNFSGVAPDVTLISIRQSSSKFAPVGDPSSTGVGDV 181 GT DCDAHGTLVAGIIA A D+ ++ FSGVAP+ T+ISIRQSS+KFAPV D S TGVGDV Sbjct 121 GTRDCDAHGTLVAGIIAGAADSSAEGFSGVAPEATVISIRQSSAKFAPVADRSGTGVGDV 180 Query 182 DTMAKAVRTAADLGASVINISSIACVPAAAAPDDRALGAALAYAVDVKNAVIVAAAGNTG 241 TMA+AVRTAADLGASVINISS+ACVPAA DDRALGAALAYAVDVKNAV+VA AGNT Sbjct 181 GTMAQAVRTAADLGASVINISSVACVPAAPLLDDRALGAALAYAVDVKNAVVVAPAGNTD 240 Query 242 GAAQCPPQAPGVTRDSVTVAVSPAWYDDYVLTVGSVNAQGEPSAFTLAGPWVDVAATGEA 301 AQCP Q P V+RD+VTV VSPAWYDDYVLTVGSVN G PS+FTLAGPWVDVAATGE Sbjct 241 SGAQCPGQRPDVSRDTVTVVVSPAWYDDYVLTVGSVNPAGAPSSFTLAGPWVDVAATGEE 300 Query 302 VTSLSPFGDGTVNRLGGQHGSIPISGTSYAAPVVSGLAALIRARFPTLTARQVMQRIEST 361 VTSLSP GDG VN L GQHGS+P+SGT +AAPVVSGLAALIRARFP LTARQVMQRI ST Sbjct 301 VTSLSPVGDGVVNALDGQHGSVPLSGTGFAAPVVSGLAALIRARFPALTARQVMQRITST 360 Query 362 AHHPPAGWDPLVGNGTVDALAAVSSDSIPQAGTATSDPAPVAVPVPRRSTPGPSDRRALH 421 AHHPPAGW+PLVGNGT+DALAA+S+DS P A A A P+ + P P+D + Sbjct 361 AHHPPAGWNPLVGNGTIDALAALSTDSPPPAPAAKP--DAAAAPITAPTMPVPADHHSRD 418 Query 422 TAFAGAAICLLALMATLAT---ASRRLRP-GRNGIAGD 455 A G AI L+ L+A LA+ RL P GR+ + GD Sbjct 419 AALGGTAIGLVVLVAVLASFGATKPRLGPSGRDSVVGD 456 >gi|183981120|ref|YP_001849411.1| membrane-anchored serine protease (mycosin), MycP4 [Mycobacterium marinum M] gi|183174446|gb|ACC39556.1| membrane-anchored serine protease (mycosin), MycP4 [Mycobacterium marinum M] Length=457 Score = 535 bits (1378), Expect = 7e-150, Method: Compositional matrix adjust. Identities = 313/442 (71%), Positives = 342/442 (78%), Gaps = 17/442 (3%) Query 24 PVAHAVSPPPIDERWLPESALPAPPRPTVQREVCTEVTAESGRAFGRAERSAQLADLD-- 81 P AHAV+PPP+DERWLP+ A P PP T QREVC T A R E +AQLA LD Sbjct 23 PAAHAVTPPPVDERWLPQPAPPGPPSRTRQREVCAAAT----WAPERPEAAAQLAGLDLP 78 Query 82 QVWRLTRGAGQRVAVIDTGVARHRRLPKVVAGGDYVFTGDGTADCDAHGTLVAGIIAAAP 141 + WRLTRG+GQRVAVIDTGVA HRRL +VAGGDYVFTGDGT DCDAHGT+VAGIIAAAP Sbjct 79 EAWRLTRGSGQRVAVIDTGVAHHRRLAHLVAGGDYVFTGDGTQDCDAHGTIVAGIIAAAP 138 Query 142 DAQSDNFSGVAPDVTLISIRQSSSKFAPVGDPSSTGVGDVDTMAKAVRTAADLGASVINI 201 D+ +D FSGVAPD T+I IRQSS+KF+PVG+ SSTGVGDVDTMA+AVRTAADLGASVINI Sbjct 139 DSATDQFSGVAPDATVIGIRQSSAKFSPVGNRSSTGVGDVDTMARAVRTAADLGASVINI 198 Query 202 SSIACVPAAAAPDDRALGAALAYAVDVKNAVIVAAAGNTGGAAQCPPQAPGVTRDSVTVA 261 S+IACV A + PDDRALGAALAYAVDVKNAVIVAAAGNTGGAAQCP Q P +RD+ TV Sbjct 199 STIACVAAESPPDDRALGAALAYAVDVKNAVIVAAAGNTGGAAQCPSQRPETSRDTATVV 258 Query 262 VSPAWYDDYVLTVGSVNAQGEPSAFTLAGPWVDVAATGEAVTSLSPFGDGTVNRLGGQHG 321 VSPAWYDDYVLTVGSVNA GEPSAFTL PWVDVAA GE VTSL+P GDGTVN L G Sbjct 259 VSPAWYDDYVLTVGSVNANGEPSAFTLPSPWVDVAAGGENVTSLNPVGDGTVNGLDDHGG 318 Query 322 SIPISGTSYAAPVVSGLAALIRARFPTLTARQVMQRIESTAHHPPAGWDPLVGNGTVDAL 381 P+SGTSYAAPVVSGLAALIRARFP LTARQVM RI STAHHPP GWDP VGNGTVD L Sbjct 319 FRPLSGTSYAAPVVSGLAALIRARFPALTARQVMARIISTAHHPPHGWDPFVGNGTVDVL 378 Query 382 AAVSSDSIPQAGTAT-SDPAPVAVPVPRRSTPGPSDRRALHTAFAGAAICLLALMATLA- 439 AAVSSD Q A P P A P + P DRRA TA +G+AICL+ L+A LA Sbjct 379 AAVSSDPAVQPAPAQPGSPTPAA---PVTTPPAQPDRRARITALSGSAICLMGLLAALAS 435 Query 440 ------TASRRLRPGRNGIAGD 455 + SR R R+ + GD Sbjct 436 RAFGGRSGSRHRRIHRDDVVGD 457 >gi|118616633|ref|YP_904965.1| membrane-anchored serine protease (mycosin), MycP4 [Mycobacterium ulcerans Agy99] gi|118568743|gb|ABL03494.1| membrane-anchored serine protease (mycosin), MycP4 [Mycobacterium ulcerans Agy99] Length=457 Score = 532 bits (1370), Expect = 6e-149, Method: Compositional matrix adjust. Identities = 311/442 (71%), Positives = 341/442 (78%), Gaps = 17/442 (3%) Query 24 PVAHAVSPPPIDERWLPESALPAPPRPTVQREVCTEVTAESGRAFGRAERSAQLADLD-- 81 P AHAV+PPP+DERWLP+ A P PP T QREVC T A R E +AQLA LD Sbjct 23 PAAHAVTPPPVDERWLPQPAPPGPPSRTRQREVCAAAT----WAPERPEAAAQLAGLDLP 78 Query 82 QVWRLTRGAGQRVAVIDTGVARHRRLPKVVAGGDYVFTGDGTADCDAHGTLVAGIIAAAP 141 + WRLTRG+GQRVAVIDTGVA HRRL +VAGGDYVFTGDGT DCDAHGT+VAGIIAAAP Sbjct 79 EAWRLTRGSGQRVAVIDTGVAHHRRLAHLVAGGDYVFTGDGTQDCDAHGTIVAGIIAAAP 138 Query 142 DAQSDNFSGVAPDVTLISIRQSSSKFAPVGDPSSTGVGDVDTMAKAVRTAADLGASVINI 201 D+ +D FSGVAPD T+I IRQSS+KF+PVG+ SSTGVGDVDTMA+AVRTAADLGASVINI Sbjct 139 DSATDQFSGVAPDATVIGIRQSSAKFSPVGNRSSTGVGDVDTMARAVRTAADLGASVINI 198 Query 202 SSIACVPAAAAPDDRALGAALAYAVDVKNAVIVAAAGNTGGAAQCPPQAPGVTRDSVTVA 261 S+IACV A + PDDRALGAALAYAVDVKNAVIVAAAGNTGGAAQCP Q P +RD+ TV Sbjct 199 STIACVAAESPPDDRALGAALAYAVDVKNAVIVAAAGNTGGAAQCPSQRPETSRDTATVV 258 Query 262 VSPAWYDDYVLTVGSVNAQGEPSAFTLAGPWVDVAATGEAVTSLSPFGDGTVNRLGGQHG 321 VSPAWYD+YVLTVGSVNA GEPSAFTL PWVDVAA GE VTSL+P GDGTVN L G Sbjct 259 VSPAWYDNYVLTVGSVNANGEPSAFTLPSPWVDVAAGGENVTSLNPVGDGTVNGLDDHGG 318 Query 322 SIPISGTSYAAPVVSGLAALIRARFPTLTARQVMQRIESTAHHPPAGWDPLVGNGTVDAL 381 P+SGTSYAAPVVSGLAALIRARFP LTARQVM RI STAHHPP GWDP VGNGTVD L Sbjct 319 FRPLSGTSYAAPVVSGLAALIRARFPALTARQVMARIISTAHHPPHGWDPFVGNGTVDVL 378 Query 382 AAVSSDSIPQAGTAT-SDPAPVAVPVPRRSTPGPSDRRALHTAFAGAAICLLALMATLA- 439 AAVSSD Q A P P A P + P DRRA TA +G+AICL+ L+ LA Sbjct 379 AAVSSDPAVQPAPAQPGSPTPAA---PVTTPPTQPDRRARITALSGSAICLMGLLGALAS 435 Query 440 ------TASRRLRPGRNGIAGD 455 + SR R R+ + GD Sbjct 436 RAFGGRSGSRHRRIHRDDVVGD 457 >gi|254819227|ref|ZP_05224228.1| peptidase [Mycobacterium intracellulare ATCC 13950] Length=430 Score = 512 bits (1319), Expect = 5e-143, Method: Compositional matrix adjust. Identities = 314/449 (70%), Positives = 346/449 (78%), Gaps = 21/449 (4%) Query 9 LLVVSALATLSGLGTPVAHAVSPPPIDERWLPESALPAPPRPTVQREVCTEVTAESGRAF 68 +L VSAL L+ GTP A AVSPP ID++WLP ALPAP RPTVQREVC +T +S Sbjct 1 MLAVSALTMLAAFGTPPAQAVSPPGIDDKWLPGPALPAPTRPTVQREVCAALTLDS--RP 58 Query 69 GRAERSAQLADLDQVWRLTRGAGQRVAVIDTGVARHRRLPKVVAGGDYVFTGDGTADCDA 128 GR + DL +VWRLTRGAGQR+AVIDTGV+RHRRLP VV GGDYV TGDGT DCDA Sbjct 59 GRNQPPGAF-DLSEVWRLTRGAGQRIAVIDTGVSRHRRLPDVVPGGDYVSTGDGTQDCDA 117 Query 129 HGTLVAGIIAAAPDAQSDNFSGVAPDVTLISIRQSSSKFAPVGDPSSTGVGDVDTMAKAV 188 HGTLVAGIIAAA D++SD FSG+AP+ TLISIRQSS+KFAP D S +GVGDVDTMAKAV Sbjct 118 HGTLVAGIIAAAADSKSDGFSGIAPEATLISIRQSSAKFAPATDRSRSGVGDVDTMAKAV 177 Query 189 RTAADLGASVINISSIACVPAAAAPDDRALGAALAYAVDVKNAVIVAAAGNTGGAAQCPP 248 RTAADLGASVINISS+ACVP AAA DDRALGAALAYAVDVKNAV+VAAAGNTGGAAQCPP Sbjct 178 RTAADLGASVINISSVACVPVAAALDDRALGAALAYAVDVKNAVVVAAAGNTGGAAQCPP 237 Query 249 QAPGVTRDSVTVAVSPAWYDDYVLTVGSVNAQGEPSAFTLAGPWVDVAATGEAVTSLSPF 308 Q P T ++TVAVSPAWYDDYVLTVGSVNA+G PS+F+LAGPWVDVAATGEAV SL+P Sbjct 238 QRPDATWQTITVAVSPAWYDDYVLTVGSVNAEGAPSSFSLAGPWVDVAATGEAVASLAPD 297 Query 309 GDGTVNRLGGQHGSIPISGTSYAAPVVSGLAALIRARFPTLTARQVMQRIESTAHHPPAG 368 P+SGTSYAAPVVSGLAALIRARFP LTARQVMQRIESTAHHPPAG Sbjct 298 ---------------PVSGTSYAAPVVSGLAALIRARFPALTARQVMQRIESTAHHPPAG 342 Query 369 WDPLVGNGTVDALAAVSSDSIPQAGTATSDPAPVAVPVPRRSTPGPSDRRALHTAFAGAA 428 WDPLVGNGT+D LAAVS+ P A T PA V +T D RA TA GAA Sbjct 343 WDPLVGNGTIDPLAAVSTGMGPPATTPKPPPAAAPAAVSPPTTRS-RDTRARDTAVRGAA 401 Query 429 ICLLALMATLATAS--RRLRPGRNGIAGD 455 +CL+AL LA RLR R+ + GD Sbjct 402 VCLVALTVALAAGGVRSRLRGARDRVPGD 430 >gi|342861876|ref|ZP_08718521.1| peptidase [Mycobacterium colombiense CECT 3035] gi|342130693|gb|EGT83997.1| peptidase [Mycobacterium colombiense CECT 3035] Length=437 Score = 508 bits (1307), Expect = 1e-141, Method: Compositional matrix adjust. Identities = 294/432 (69%), Positives = 329/432 (77%), Gaps = 20/432 (4%) Query 8 RLLVVSALATLSGLGTPVAHAVSPPPIDERWLPESALPAPPRPTVQREVCTEVTAESGRA 67 RLLV AL S GTP A A SPP +D+RWLP+ LPA P PTVQRE+C +TA++G Sbjct 8 RLLVALALTLESAFGTPTAQAFSPPDVDDRWLPKPGLPASPWPTVQREICAPMTADAGP- 66 Query 68 FGRAERSAQLADLDQVWRLTRGAGQRVAVIDTGVARHRRLPKVVAGGDYVFTGDGTADCD 127 GR ++S L DL VW LTRGAGQRVAVIDTG++RHRRLP VV GGDYV TGDGT DCD Sbjct 67 -GRNQQSG-LGDLSAVWPLTRGAGQRVAVIDTGISRHRRLPDVVPGGDYVSTGDGTQDCD 124 Query 128 AHGTLVAGIIAAAPDAQSDNFSGVAPDVTLISIRQSSSKFAPVGDPSSTGVGDVDTMAKA 187 AHGTLVAGIIAA D+++D FSGVAP+ TLISIRQSS+KFAP GD S GVGDVDT+AKA Sbjct 125 AHGTLVAGIIAATADSKADGFSGVAPEATLISIRQSSAKFAPTGDRSRVGVGDVDTLAKA 184 Query 188 VRTAADLGASVINISSIACVPAAAAPDDRALGAALAYAVDVKNAVIVAAAGNTGGAAQCP 247 VRTAADLGASVINISS+AC P A A DDRALGAALAYAVDVKN+VIVAAAGNTGGA QCP Sbjct 185 VRTAADLGASVINISSVACAPVATALDDRALGAALAYAVDVKNSVIVAAAGNTGGAGQCP 244 Query 248 PQAPGVTRDSVTVAVSPAWYDDYVLTVGSVNAQGEPSAFTLAGPWVDVAATGEAVTSLSP 307 Q VT ++TVAVSPAWYDDYVLTVGSVN+ G PS FTLAGPWVDVAA GEAV SL+P Sbjct 245 SQRADVTWQTITVAVSPAWYDDYVLTVGSVNSHGAPSPFTLAGPWVDVAAPGEAVASLAP 304 Query 308 FGDGTVNRLGGQHGSIPISGTSYAAPVVSGLAALIRARFPTLTARQVMQRIESTAHHPPA 367 P+SGTS+AAP+VSGLAALIRARFP LTARQVMQRIE+TAHHPPA Sbjct 305 E---------------PVSGTSFAAPMVSGLAALIRARFPALTARQVMQRIETTAHHPPA 349 Query 368 GWDPLVGNGTVDALAAVSSDSIPQAGTATSDPAPVAVPVPRRSTPGPSDRRALHTAFAGA 427 GWDP+VGNGT+D +AAVS+ + P P VP+ P D RA TA GA Sbjct 350 GWDPVVGNGTIDPVAAVSTGM--GPAADHAAPPPAPVPIAPSPPIPPRDSRARDTALRGA 407 Query 428 AICLLALMATLA 439 A+CL+AL LA Sbjct 408 AVCLVALTVALA 419 >gi|254776824|ref|ZP_05218340.1| peptidase [Mycobacterium avium subsp. avium ATCC 25291] Length=429 Score = 506 bits (1302), Expect = 5e-141, Method: Compositional matrix adjust. Identities = 278/382 (73%), Positives = 309/382 (81%), Gaps = 18/382 (4%) Query 7 LRLLVVSALATLSGLGTPVAHAVSPPPIDERWLPESALPAPPRPTVQREVCTEVTAESGR 66 +RLL VSAL L TP AHAVSPP +D++WLP+ A PAPP PT QREVC +TA+SG Sbjct 1 MRLLAVSALTMLPVFETPPAHAVSPPAVDDKWLPKPARPAPPWPTAQREVCATLTADSGP 60 Query 67 AFGRAERSAQLADLDQVWRLTRGAGQRVAVIDTGVARHRRLPKVVAGGDYVFTGDGTADC 126 A +DL VW+L+RG GQRVAVIDTGVARHRRLP VV GGDYV TGDG DC Sbjct 61 G---RRGPAGGSDLSAVWQLSRGTGQRVAVIDTGVARHRRLPAVVPGGDYVSTGDGIQDC 117 Query 127 DAHGTLVAGIIAAAPDAQSDNFSGVAPDVTLISIRQSSSKFAPVGDPSSTGVGDVDTMAK 186 DAHGTLVAGIIAAA D +SD F+G+AP+ TLISIRQSS+KF P G+ S GVGDVDT+AK Sbjct 118 DAHGTLVAGIIAAAADPKSDEFTGIAPEATLISIRQSSAKFGPAGNRSGGGVGDVDTLAK 177 Query 187 AVRTAADLGASVINISSIACVPAAAAPDDRALGAALAYAVDVKNAVIVAAAGNTGGAAQC 246 A+RTAADLGASVINISS+AC P A+APDDRALGAALAYAVDVKNA +VAAAGNTGGA QC Sbjct 178 AIRTAADLGASVINISSVACAPVASAPDDRALGAALAYAVDVKNAGVVAAAGNTGGAGQC 237 Query 247 PPQAPGVTRDSVTVAVSPAWYDDYVLTVGSVNAQGEPSAFTLAGPWVDVAATGEAVTSLS 306 PPQ P T ++TVAVSPAWYDDYVLTVGSVNA G PSAF+LAGPWVDVAA GEAVTSL+ Sbjct 238 PPQRPDATWQTITVAVSPAWYDDYVLTVGSVNADGAPSAFSLAGPWVDVAAPGEAVTSLA 297 Query 307 PFGDGTVNRLGGQHGSIPISGTSYAAPVVSGLAALIRARFPTLTARQVMQRIESTAHHPP 366 P P+SGTSYAAPVVSGLAALIRARFP LTARQVMQRIE+TAHHPP Sbjct 298 PE---------------PVSGTSYAAPVVSGLAALIRARFPALTARQVMQRIEATAHHPP 342 Query 367 AGWDPLVGNGTVDALAAVSSDS 388 AGWDPLVG+GTVD LAAVS+++ Sbjct 343 AGWDPLVGHGTVDPLAAVSAET 364 >gi|118465498|ref|YP_883527.1| peptidase [Mycobacterium avium 104] gi|118166785|gb|ABK67682.1| peptidase families S8 and S53 domain protein [Mycobacterium avium 104] Length=429 Score = 498 bits (1281), Expect = 1e-138, Method: Compositional matrix adjust. Identities = 278/382 (73%), Positives = 307/382 (81%), Gaps = 18/382 (4%) Query 7 LRLLVVSALATLSGLGTPVAHAVSPPPIDERWLPESALPAPPRPTVQREVCTEVTAESGR 66 +RLL VSAL L TP AHAVSPP +D++WLP+ A PAPP PT QREVC +TA+SG Sbjct 1 MRLLAVSALTMLPVFETPPAHAVSPPAVDDKWLPKPARPAPPWPTAQREVCATLTADSGP 60 Query 67 AFGRAERSAQLADLDQVWRLTRGAGQRVAVIDTGVARHRRLPKVVAGGDYVFTGDGTADC 126 A +DL VW+L+RG GQRVAVIDTGVARHRRLP VV GGDYV TGDG DC Sbjct 61 G---RRGPAGGSDLSAVWQLSRGTGQRVAVIDTGVARHRRLPAVVPGGDYVSTGDGIQDC 117 Query 127 DAHGTLVAGIIAAAPDAQSDNFSGVAPDVTLISIRQSSSKFAPVGDPSSTGVGDVDTMAK 186 DAHGTLVAGIIAAA D +SD FSG+AP+ TLISIRQSS+KF P G+ S GVGDVDT+AK Sbjct 118 DAHGTLVAGIIAAAADPKSDEFSGIAPEATLISIRQSSAKFGPAGNRSGGGVGDVDTLAK 177 Query 187 AVRTAADLGASVINISSIACVPAAAAPDDRALGAALAYAVDVKNAVIVAAAGNTGGAAQC 246 AVRTAADLGASVINISS+AC P +APDDRALGAALAYAVDVKNAV+VAAAGNTGG QC Sbjct 178 AVRTAADLGASVINISSVACAPVVSAPDDRALGAALAYAVDVKNAVVVAAAGNTGGPGQC 237 Query 247 PPQAPGVTRDSVTVAVSPAWYDDYVLTVGSVNAQGEPSAFTLAGPWVDVAATGEAVTSLS 306 PPQ P T ++TVAVSPAWYDDYVLTVGSVNA G PS F+LAGPWVDVAA GEAVTSL+ Sbjct 238 PPQRPDATWQTITVAVSPAWYDDYVLTVGSVNADGAPSTFSLAGPWVDVAAPGEAVTSLA 297 Query 307 PFGDGTVNRLGGQHGSIPISGTSYAAPVVSGLAALIRARFPTLTARQVMQRIESTAHHPP 366 P P+SGTSYAAPVVSGLAALIRARFP LTARQVMQRIE+TAHHPP Sbjct 298 PE---------------PVSGTSYAAPVVSGLAALIRARFPALTARQVMQRIEATAHHPP 342 Query 367 AGWDPLVGNGTVDALAAVSSDS 388 AGWDPLVG+GTVD LAAVS+++ Sbjct 343 AGWDPLVGHGTVDPLAAVSAET 364 >gi|41410337|ref|NP_963173.1| hypothetical protein MAP4239c [Mycobacterium avium subsp. paratuberculosis K-10] gi|41399171|gb|AAS06789.1| hypothetical protein MAP_4239c [Mycobacterium avium subsp. paratuberculosis K-10] Length=432 Score = 489 bits (1260), Expect = 3e-136, Method: Compositional matrix adjust. Identities = 280/384 (73%), Positives = 312/384 (82%), Gaps = 18/384 (4%) Query 5 RTLRLLVVSALATLSGLGTPVAHAVSPPPIDERWLPESALPAPPRPTVQREVCTEVTAES 64 R +RLL VSAL L TP AHAVSPP ++++WLP+ A PAPP PT QREVC +TA+S Sbjct 2 RVVRLLAVSALTMLPVFETPPAHAVSPPAVEDKWLPKPARPAPPWPTAQREVCATLTADS 61 Query 65 GRAFGRAERSAQLADLDQVWRLTRGAGQRVAVIDTGVARHRRLPKVVAGGDYVFTGDGTA 124 G A +DL VW+L+RGAGQR+AVIDTGVARHRRLP VV GGDYV TGDG Sbjct 62 GPG---PRGPAGGSDLSAVWQLSRGAGQRIAVIDTGVARHRRLPGVVPGGDYVSTGDGIQ 118 Query 125 DCDAHGTLVAGIIAAAPDAQSDNFSGVAPDVTLISIRQSSSKFAPVGDPSSTGVGDVDTM 184 DCDAHGTLVAGIIAAA D +SD FSG+AP+ TLISIRQSS+KF P G+ S GVGDVDT+ Sbjct 119 DCDAHGTLVAGIIAAAADPKSDEFSGIAPEATLISIRQSSAKFGPAGNRSGGGVGDVDTL 178 Query 185 AKAVRTAADLGASVINISSIACVPAAAAPDDRALGAALAYAVDVKNAVIVAAAGNTGGAA 244 A+AVRTAADLGASVINISS+AC P A+APDDRALGAALAYAVDVKNAV+VAAAGNTGGA Sbjct 179 AQAVRTAADLGASVINISSVACAPVASAPDDRALGAALAYAVDVKNAVVVAAAGNTGGAG 238 Query 245 QCPPQAPGVTRDSVTVAVSPAWYDDYVLTVGSVNAQGEPSAFTLAGPWVDVAATGEAVTS 304 QCPPQ P T ++TVAVSPAWYDDYVLTVGSVNA G PSAF+LAGPWVDVAA GEAVTS Sbjct 239 QCPPQQPDATWQTITVAVSPAWYDDYVLTVGSVNADGAPSAFSLAGPWVDVAAPGEAVTS 298 Query 305 LSPFGDGTVNRLGGQHGSIPISGTSYAAPVVSGLAALIRARFPTLTARQVMQRIESTAHH 364 L+P P+SGTSYAAPVVSGLAALIRARFP LTARQVMQRIE+TAHH Sbjct 299 LAPE---------------PVSGTSYAAPVVSGLAALIRARFPALTARQVMQRIEATAHH 343 Query 365 PPAGWDPLVGNGTVDALAAVSSDS 388 PPAGWDPLVG+GTVD LAAVS+++ Sbjct 344 PPAGWDPLVGHGTVDPLAAVSAET 367 >gi|336460698|gb|EGO39588.1| type VII secretion-associated serine protease mycosin [Mycobacterium avium subsp. paratuberculosis S397] Length=432 Score = 489 bits (1259), Expect = 4e-136, Method: Compositional matrix adjust. Identities = 280/384 (73%), Positives = 312/384 (82%), Gaps = 18/384 (4%) Query 5 RTLRLLVVSALATLSGLGTPVAHAVSPPPIDERWLPESALPAPPRPTVQREVCTEVTAES 64 R +RLL VSAL L TP AHAVSPP ++++WLP+ A PAPP PT QREVC +TA+S Sbjct 2 RVVRLLAVSALTMLPVFETPPAHAVSPPAVEDKWLPKPARPAPPWPTAQREVCATLTADS 61 Query 65 GRAFGRAERSAQLADLDQVWRLTRGAGQRVAVIDTGVARHRRLPKVVAGGDYVFTGDGTA 124 G A +DL VW+L+RGAGQR+AVIDTGVARHRRLP VV GGDYV TGDG Sbjct 62 GPG---PRGPAGGSDLSAVWQLSRGAGQRIAVIDTGVARHRRLPGVVPGGDYVSTGDGIQ 118 Query 125 DCDAHGTLVAGIIAAAPDAQSDNFSGVAPDVTLISIRQSSSKFAPVGDPSSTGVGDVDTM 184 DCDAHGTLVAGIIAAA D +SD FSG+AP+ TLISIRQSS+KF P G+ S GVGDVDT+ Sbjct 119 DCDAHGTLVAGIIAAAADPKSDEFSGIAPEATLISIRQSSAKFGPAGNRSGGGVGDVDTL 178 Query 185 AKAVRTAADLGASVINISSIACVPAAAAPDDRALGAALAYAVDVKNAVIVAAAGNTGGAA 244 A+AVRTAADLGASVINISS+AC P A+APDDRALGAALAYAVDVKNAV+VAAAGNTGGA Sbjct 179 AQAVRTAADLGASVINISSVACAPVASAPDDRALGAALAYAVDVKNAVVVAAAGNTGGAG 238 Query 245 QCPPQAPGVTRDSVTVAVSPAWYDDYVLTVGSVNAQGEPSAFTLAGPWVDVAATGEAVTS 304 QCPPQ P T ++TVAVSPAWYDDYVLTVGSVNA G PSAF+LAGPWVDVAA GEAVTS Sbjct 239 QCPPQRPDATWQTITVAVSPAWYDDYVLTVGSVNADGAPSAFSLAGPWVDVAAPGEAVTS 298 Query 305 LSPFGDGTVNRLGGQHGSIPISGTSYAAPVVSGLAALIRARFPTLTARQVMQRIESTAHH 364 L+P P+SGTSYAAPVVSGLAALIRARFP LTARQVMQRIE+TAHH Sbjct 299 LAPE---------------PVSGTSYAAPVVSGLAALIRARFPALTARQVMQRIEATAHH 343 Query 365 PPAGWDPLVGNGTVDALAAVSSDS 388 PPAGWDPLVG+GTVD LAAVS+++ Sbjct 344 PPAGWDPLVGHGTVDPLAAVSAET 367 >gi|296168730|ref|ZP_06850440.1| serine protease [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295896567|gb|EFG76209.1| serine protease [Mycobacterium parascrofulaceum ATCC BAA-614] Length=387 Score = 475 bits (1222), Expect = 9e-132, Method: Compositional matrix adjust. Identities = 284/387 (74%), Positives = 311/387 (81%), Gaps = 20/387 (5%) Query 1 MTTSRTLRLLVVSALATLSGLGTPVAHAVSPPPIDERWLPESALPAPPRPTVQREVCTEV 60 M TSR RLL VSALA S LGTP A A+SPPP+D+ WLP+ A P PP PTVQRE C + Sbjct 1 MITSRVTRLLSVSALACASLLGTPSAQAISPPPVDDTWLPKPARPVPPWPTVQREACAAI 60 Query 61 TAESGRAFGRAERSAQLADLDQVWRLTRGAGQRVAVIDTGVARHRRLPKVVAGGDYVFTG 120 T +G A G A+L DL +VWRLTRGAGQRVAVIDTGV+RHR LP VVAGGDYV TG Sbjct 61 T--TGSAPG--PLMARL-DLPRVWRLTRGAGQRVAVIDTGVSRHRLLPDVVAGGDYVSTG 115 Query 121 DGTADCDAHGTLVAGIIAAAPDAQSDNFSGVAPDVTLISIRQSSSKFAPVGDPSSTGVGD 180 DGT DCDAHGTLVAGIIAA D+ + +F GVAP+ T+IS+RQSS+KF+P D S GVGD Sbjct 116 DGTQDCDAHGTLVAGIIAATADSPAGDFGGVAPEATVISVRQSSAKFSPASDRSRAGVGD 175 Query 181 VDTMAKAVRTAADLGASVINISSIACVPAAAAPDDRALGAALAYAVDVKNAVIVAAAGNT 240 VDTMAKAVRTAADLGASVINISS+ACV AA+A DDRALGAALAYAVDVKNAV+VAAAGNT Sbjct 176 VDTMAKAVRTAADLGASVINISSVACVAAASALDDRALGAALAYAVDVKNAVVVAAAGNT 235 Query 241 GGAAQCPPQAPGVTRDSVTVAVSPAWYDDYVLTVGSVNAQGEPSAFTLAGPWVDVAATGE 300 GG+A CPPQ T D+VTVAVSPAWYDDYVLTVGSVN G PS FTLAGPWVDVAA GE Sbjct 236 GGSAPCPPQRSDATWDTVTVAVSPAWYDDYVLTVGSVNPGGGPSTFTLAGPWVDVAAPGE 295 Query 301 AVTSLSPFGDGTVNRLGGQHGSIPISGTSYAAPVVSGLAALIRARFPTLTARQVMQRIES 360 VT L GS P+SGTS+AAPVVSGLAALIRARFP LTARQVMQRIES Sbjct 296 GVTPL---------------GSEPVSGTSFAAPVVSGLAALIRARFPALTARQVMQRIES 340 Query 361 TAHHPPAGWDPLVGNGTVDALAAVSSD 387 TAHHP AGWDPLVG+GT+DALAAVS+D Sbjct 341 TAHHPAAGWDPLVGHGTIDALAAVSTD 367 >gi|120402456|ref|YP_952285.1| peptidase S8/S53 subtilisin kexin sedolisin [Mycobacterium vanbaalenii PYR-1] gi|119955274|gb|ABM12279.1| peptidase S8 and S53, subtilisin, kexin, sedolisin [Mycobacterium vanbaalenii PYR-1] Length=444 Score = 411 bits (1056), Expect = 1e-112, Method: Compositional matrix adjust. Identities = 254/434 (59%), Positives = 300/434 (70%), Gaps = 26/434 (5%) Query 24 PVAHAVSPPPIDERWLPESALPAPPRPTVQREVCTEVTAESGRAFGRAERSAQLADLDQV 83 P A AV PP +DER LP AP PTVQ + C GR DL V Sbjct 23 PSADAVGPPAVDERLLPAPGPVAPAHPTVQHDECVTAPTSPVDVPGRPHG----IDLPSV 78 Query 84 WRLTRGAGQRVAVIDTGVARHRRLPKVVAGGDYVFTGDGTADCDAHGTLVAGIIAAAPD- 142 W LTRGAGQ VAVIDTGVARHRRLP ++AGGDYV DGT+DCD HGT+VAGII A+ D Sbjct 79 WALTRGAGQTVAVIDTGVARHRRLPHLIAGGDYVSGQDGTSDCDGHGTIVAGIIGASADP 138 Query 143 AQSDNFSGVAPDVTLISIRQSSSKFAPVGDPSSTGVGDVDTMAKAVRTAADLGASVINIS 202 A + F+G+APDV+L+SIRQSS++F V DP TGVGDV+T+A AVRTAADLGA+V+NIS Sbjct 139 ADTGGFAGIAPDVSLLSIRQSSNRFRAVDDPGGTGVGDVETLATAVRTAADLGATVLNIS 198 Query 203 SIACVPAAAAPDDRALGAALAYAVDVKNAVIVAAAGNTGGAAQCPPQAPGVTRD--SVTV 260 ++AC+P A DDRALGAALAYAVDVKN V+V AAGN GGA QC P D +VT+ Sbjct 199 TVACLPVDAGLDDRALGAALAYAVDVKNVVVVTAAGNVGGAGQCTQHNPRRPADAGAVTM 258 Query 261 AVSPAWYDDYVLTVGSVNAQGEPSAFTLAGPWVDVAATGEAVTSLSPFGDGTVNRLGGQH 320 SPAWYDDYVLTVGS+ + G S F+LAGPWVDVAA GE+V SL+P GDG V+ Sbjct 259 VASPAWYDDYVLTVGSIGSDGIASEFSLAGPWVDVAAPGESVVSLAPAGDGLVDV---AP 315 Query 321 GSIPISGTSYAAPVVSGLAALIRARFPTLTARQVMQRIESTAHHPPAGWDPLVGNGTVDA 380 +PISGTSYA PVVS +AAL+RAR P LTARQVM+ IE TAH PP+GWDP+VG+G VDA Sbjct 316 SGLPISGTSYAVPVVSAIAALVRARSPGLTARQVMRVIEDTAHPPPSGWDPVVGHGVVDA 375 Query 381 LAAVSSDSIPQAGTATSDP-----APVAVPVPRRSTPGPSDRRALHTAFAGAAICLLALM 435 LAAV++ T ++DP APV PVP R + S R ALH A + L A + Sbjct 376 LAAVTA-------TGSADPVSAGVAPVG-PVPPRPSESVSGRTALHAAL--GCLALTACV 425 Query 436 ATLATASRRL-RPG 448 A ++TA RR RPG Sbjct 426 AVVSTAVRRSGRPG 439 >gi|126433754|ref|YP_001069445.1| peptidase S8/S53 subtilisin kexin sedolisin [Mycobacterium sp. JLS] gi|126233554|gb|ABN96954.1| peptidase S8 and S53, subtilisin, kexin, sedolisin [Mycobacterium sp. JLS] Length=445 Score = 387 bits (994), Expect = 2e-105, Method: Compositional matrix adjust. Identities = 257/452 (57%), Positives = 301/452 (67%), Gaps = 31/452 (6%) Query 3 TSRTLRLLVVSALATLSGLGTPVAHAVSPPPIDERWLPESALPAPPRPTVQREVCTEVTA 62 T+ TL L+V+A+ + P AV+PP +D+ +LP +A PAPP+ T QR C+ A Sbjct 6 TAATLTGLLVAAVPLAT---APEVSAVTPPAVDDAFLPAAAPPAPPQRTEQRAECS--GA 60 Query 63 ESGRAFGRAERSAQLADLDQVWRLTRGAGQRVAVIDTGVARHRRLPKVVAGGDYVFTGDG 122 E R R + +L VW LTRGAGQ VAVIDTGVARHR LP+++ GGDYV TGDG Sbjct 61 ERDRDPPADARQLDMLNLQSVWPLTRGAGQTVAVIDTGVARHRLLPRLMPGGDYVSTGDG 120 Query 123 TADCDAHGTLVAGIIAAAPDAQSDNFSGVAPDVTLISIRQSSSKFAPVGDPSSTGVGDVD 182 T DCD HGTLVAGI+AA + F+GVAPD L+ IRQSS+KF DP TG GDV Sbjct 121 TDDCDGHGTLVAGIVAA-----TGEFTGVAPDAALLGIRQSSNKFGAADDPGVTGYGDVQ 175 Query 183 TMAKAVRTAADLGASVINISSIACVPAAAAPDDRALGAALAYAVDVKNAVIVAAAGNTGG 242 T+A AVR AADLGA+VIN+SS+AC+ AA A DDRALGAALAYAVDV+NAV+V AAGN GG Sbjct 176 TLATAVRAAADLGATVINVSSVACLAAADALDDRALGAALAYAVDVRNAVVVTAAGNVGG 235 Query 243 AAQCPPQ---APGV-TRDSVTVAVSPAWYDDYVLTVGSVNAQGEPSAFTLAGPWVDVAAT 298 QCP Q PG SV SPAWYDD VLTVGSV G PS F+LAGPWVDVAA Sbjct 236 PGQCPTQNATQPGRPDWQSVESVASPAWYDDLVLTVGSVRTDGAPSEFSLAGPWVDVAAP 295 Query 299 GEAVTSLSPFGDGTVNRLGGQHGSIPISGTSYAAPVVSGLAALIRARFPTLTARQVMQRI 358 GE V SL P GDG V+ L G I+GTSYAAPVVSG+AAL+R+R+P LTARQVMQRI Sbjct 296 GEHVVSLDPDGDGLVDALPTADGDASIAGTSYAAPVVSGVAALVRSRWPHLTARQVMQRI 355 Query 359 ESTAHHPPAGWDPLVGNGTVDALAAVSSDSIPQAGTATSDPAPVAVPVPRRSTPGPS--- 415 E TAH PPAGWDP+VG+G VD AAVS +P T T P RS P+ Sbjct 356 EDTAHRPPAGWDPVVGHGVVDVAAAVSG-GVPADTTET----------PARSLHAPADVP 404 Query 416 -DRRALHTAFAGAAIC--LLALMATLATASRR 444 D R A AGA IC + L+A A++ RR Sbjct 405 HDGRPRRVAMAGAGICVAITVLVALSASSHRR 436 >gi|108798096|ref|YP_638293.1| peptidase S8/S53 subtilisin kexin sedolisin [Mycobacterium sp. MCS] gi|119867192|ref|YP_937144.1| peptidase S8/S53 subtilisin kexin sedolisin [Mycobacterium sp. KMS] gi|108768515|gb|ABG07237.1| peptidase S8 and S53, subtilisin, kexin, sedolisin [Mycobacterium sp. MCS] gi|119693281|gb|ABL90354.1| peptidase S8 and S53, subtilisin, kexin, sedolisin [Mycobacterium sp. KMS] Length=445 Score = 384 bits (986), Expect = 2e-104, Method: Compositional matrix adjust. Identities = 259/454 (58%), Positives = 301/454 (67%), Gaps = 35/454 (7%) Query 3 TSRTLRLLVVSA--LATLSGLGTPVAHAVSPPPIDERWLPESALPAPPRPTVQREVCTEV 60 T+ TL L+V+A LAT P AV+PP +D+ +LP +A PAPP+ T QR C+ Sbjct 6 TAATLTGLLVAAVPLAT-----APEVSAVTPPAVDDAFLPAAAPPAPPQRTEQRAECS-- 58 Query 61 TAESGRAFGRAERSAQLADLDQVWRLTRGAGQRVAVIDTGVARHRRLPKVVAGGDYVFTG 120 AE R R + +L VW LTRGAGQ VAVIDTGVARHR LP+++ GGDYV TG Sbjct 59 GAERDRDPPADARQLDMLNLQSVWPLTRGAGQTVAVIDTGVARHRLLPRLMPGGDYVSTG 118 Query 121 DGTADCDAHGTLVAGIIAAAPDAQSDNFSGVAPDVTLISIRQSSSKFAPVGDPSSTGVGD 180 DGT DCD HGTLVAGI+AA + F+GVAPD L+ IRQSS+KF DP TG GD Sbjct 119 DGTDDCDGHGTLVAGIVAA-----TGEFTGVAPDAALLGIRQSSNKFGAADDPGVTGYGD 173 Query 181 VDTMAKAVRTAADLGASVINISSIACVPAAAAPDDRALGAALAYAVDVKNAVIVAAAGNT 240 V T+A AVR AADLGA+VIN+SS+AC+ AA A DDRALGAALAYAVDV+NAV+V AAGN Sbjct 174 VQTLATAVRAAADLGATVINVSSVACLAAADALDDRALGAALAYAVDVRNAVVVTAAGNV 233 Query 241 GGAAQCPPQ---APGV-TRDSVTVAVSPAWYDDYVLTVGSVNAQGEPSAFTLAGPWVDVA 296 GG QCP Q PG SV SPAWYDD VLTVGSV G PS F+LAGPWVDVA Sbjct 234 GGPGQCPTQNATQPGRPDWQSVESVASPAWYDDLVLTVGSVRTDGAPSEFSLAGPWVDVA 293 Query 297 ATGEAVTSLSPFGDGTVNRLGGQHGSIPISGTSYAAPVVSGLAALIRARFPTLTARQVMQ 356 A GE V SL P GDG V+ L G I+GTSYAAPVVSG+AAL+R+R+P LTARQVMQ Sbjct 294 APGEHVVSLDPDGDGLVDALPTADGDASIAGTSYAAPVVSGVAALVRSRWPHLTARQVMQ 353 Query 357 RIESTAHHPPAGWDPLVGNGTVDALAAVSSDSIPQAGTATSDPAPVAVPVPRRSTPGPS- 415 RIE TAH PPAGWD +VG+G VD AAVS +P T T P RS P+ Sbjct 354 RIEDTAHRPPAGWDSVVGHGVVDVAAAVSG-GVPADTTET----------PARSLHAPAD 402 Query 416 ---DRRALHTAFAGAAIC--LLALMATLATASRR 444 D R A AGA IC + L+A A++ RR Sbjct 403 VPHDGRPRRVAMAGAGICVAITVLVALSASSHRR 436 >gi|145225537|ref|YP_001136215.1| peptidase S8/S53 subtilisin kexin sedolisin [Mycobacterium gilvum PYR-GCK] gi|145218023|gb|ABP47427.1| peptidase S8 and S53, subtilisin, kexin, sedolisin [Mycobacterium gilvum PYR-GCK] Length=437 Score = 383 bits (983), Expect = 5e-104, Method: Compositional matrix adjust. Identities = 232/388 (60%), Positives = 270/388 (70%), Gaps = 18/388 (4%) Query 4 SRTLRLLVVSALATLSGLGTPVAHAVSPPPIDERWLPESALPAPPRPTVQREVCTEVTAE 63 +RT R+ V+A+A + TP A A+ PPP+D LP + PAP +PTVQ C Sbjct 2 TRTWRVAAVTAIALMHT--TPTAAAIGPPPVDTLRLPTADPPAPAQPTVQFTDCVAAPPA 59 Query 64 SGRAFGRAERSAQLA--DLDQVWRLTRGAGQRVAVIDTGVARHRRLPKVVAGGDYVFTGD 121 + QLA DL VW LTRGAGQ VAVIDTG ARHRRLP +V GGDYV D Sbjct 60 A------GSAPGQLAGMDLPTVWALTRGAGQTVAVIDTGTARHRRLPHLVPGGDYVSHRD 113 Query 122 GTADCDAHGTLVAGIIAAAPDAQS-DNFSGVAPDVTLISIRQSSSKFAPVGDPSSTGVGD 180 GT DCD HGTLVAGII A+PDA F+G+APDV+L+SIRQSS+KF V DP +GVGD Sbjct 114 GTDDCDGHGTLVAGIIGASPDAADPGGFTGIAPDVSLLSIRQSSNKFRAVDDPGGSGVGD 173 Query 181 VDTMAKAVRTAADLGASVINISSIACVPAAAAPDDRALGAALAYAVDVKNAVIVAAAGNT 240 V+T+A AVRTAADLGA+VINIS++AC+P AA DDR LGAAL+YAV+ KN V+V AAGN Sbjct 174 VETLAAAVRTAADLGATVINISTVACLPVAAGLDDRTLGAALSYAVEAKNVVVVTAAGNV 233 Query 241 GGAAQCP---PQAPGVTRDSVTVAVSPAWYDDYVLTVGSVNAQGEPSAFTLAGPWVDVAA 297 GG QC P+ G D V SPAWYDDYVLTVGSV G PS F+LAGPWVDVAA Sbjct 234 GGPGQCQDPNPRDVGAA-DQVRTVASPAWYDDYVLTVGSVGTDGSPSEFSLAGPWVDVAA 292 Query 298 TGEAVTSLSPFGDGTVNRLGGQHGSIPISGTSYAAPVVSGLAALIRARFPTLTARQVMQR 357 TGE V SL+ GDG +R ++GTSYA PVVS +AAL+RARFP +TARQVMQR Sbjct 293 TGEGVVSLAATGDGLADR---SPSDAALTGTSYAVPVVSAVAALVRARFPEMTARQVMQR 349 Query 358 IESTAHHPPAGWDPLVGNGTVDALAAVS 385 IE TA A WDP+VG+G VDALAAVS Sbjct 350 IEDTARPSSAEWDPVVGHGVVDALAAVS 377 >gi|315445890|ref|YP_004078769.1| subtilisin-like serine protease [Mycobacterium sp. Spyr1] gi|315264193|gb|ADU00935.1| subtilisin-like serine protease [Mycobacterium sp. Spyr1] Length=431 Score = 377 bits (969), Expect = 2e-102, Method: Compositional matrix adjust. Identities = 227/369 (62%), Positives = 260/369 (71%), Gaps = 16/369 (4%) Query 23 TPVAHAVSPPPIDERWLPESALPAPPRPTVQREVCTEVTAESGRAFGRAERSAQLA--DL 80 TP A A+ PPP+D LP + PAP +PTVQ C + QLA DL Sbjct 13 TPTAAAIGPPPVDTLRLPTADPPAPAQPTVQFTDCVAAPPAA------GSAPGQLAGMDL 66 Query 81 DQVWRLTRGAGQRVAVIDTGVARHRRLPKVVAGGDYVFTGDGTADCDAHGTLVAGIIAAA 140 VW LTRGAGQ VAVIDTG ARHRRLP +V GGDYV DGT DCD HGTLVAGII A+ Sbjct 67 PTVWALTRGAGQTVAVIDTGTARHRRLPHLVPGGDYVSHRDGTDDCDGHGTLVAGIIGAS 126 Query 141 PDAQS-DNFSGVAPDVTLISIRQSSSKFAPVGDPSSTGVGDVDTMAKAVRTAADLGASVI 199 PDA F+G+APDV+L+SIRQSS+KF V DP +GVGDV+T+A AVRTAADLGA+VI Sbjct 127 PDAADPGGFTGIAPDVSLLSIRQSSNKFRAVDDPGGSGVGDVETLAAAVRTAADLGATVI 186 Query 200 NISSIACVPAAAAPDDRALGAALAYAVDVKNAVIVAAAGNTGGAAQCP---PQAPGVTRD 256 NIS++AC+P AA DDR LGAAL+YAV+ KN V+V AAGN GG QC P+ G Sbjct 187 NISTVACLPVAAGLDDRTLGAALSYAVEAKNVVVVTAAGNVGGPGQCQDPNPRDVGAAHQ 246 Query 257 SVTVAVSPAWYDDYVLTVGSVNAQGEPSAFTLAGPWVDVAATGEAVTSLSPFGDGTVNRL 316 TVA SPAWYDDYVLTVGSV G PS F+LAGPWVDVAATGE V SL+ GDG +R Sbjct 247 VRTVA-SPAWYDDYVLTVGSVGTDGSPSDFSLAGPWVDVAATGEGVVSLAATGDGLADR- 304 Query 317 GGQHGSIPISGTSYAAPVVSGLAALIRARFPTLTARQVMQRIESTAHHPPAGWDPLVGNG 376 ++GTSYA PVVS +AAL+RARFP +TARQVMQRIE TA A WDP+VG+G Sbjct 305 --SPSDAALTGTSYAVPVVSAVAALVRARFPEMTARQVMQRIEDTARPSSAEWDPVVGHG 362 Query 377 TVDALAAVS 385 VDALAAVS Sbjct 363 VVDALAAVS 371 >gi|169630837|ref|YP_001704486.1| putative protease [Mycobacterium abscessus ATCC 19977] gi|169242804|emb|CAM63832.1| Putative protease [Mycobacterium abscessus] Length=479 Score = 364 bits (934), Expect = 2e-98, Method: Compositional matrix adjust. Identities = 224/403 (56%), Positives = 269/403 (67%), Gaps = 17/403 (4%) Query 2 TTSRTLRLLVVSALATLSGLGTPVAHAVSPPPIDERWLPESALPAPPRPTVQREVCTEVT 61 T + L + S LAT S AHA +P P+D LP PAP PT Q+E+C Sbjct 11 TAGAVVMLAMSSQLATGSMHVMATAHAFAPLPVDPSMLPGPRPPAPIEPTEQKELCRFPG 70 Query 62 AESGRAFGRAERSAQLADLDQVWRLTRGAGQRVAVIDTGVARHRRLPKVVAGGDYVFTG- 120 + R + + DL VW+L+RGAGQ VAVIDTGVAR RLP ++ GGDYVF G Sbjct 71 IDPKRDLNKVPTQQRGLDLPLVWQLSRGAGQTVAVIDTGVARSPRLPPLIPGGDYVFEGG 130 Query 121 DGTADCDAHGTLVAGIIAAAPDAQ-SDNFSGVAPDVTLISIRQSSSKFAPVG-------D 172 +GT DCDAHGT+VAGIIAAAPD + FSG+APDV+LI+IRQSS+KFA D Sbjct 131 NGTQDCDAHGTIVAGIIAAAPDPTGASAFSGIAPDVSLITIRQSSAKFAVKNKGGNDRDD 190 Query 173 PSS-TGVGDVDTMAKAVRTAADLGASVINISSIACVPAAAAPDDRALGAALAYAVDVKNA 231 PS +GVG+VDT+A AVRTAAD+GA+VINIS +AC A DDR LGAAL YAVDVKN Sbjct 191 PSKISGVGNVDTLAMAVRTAADMGATVINISEVACASAKQFLDDRPLGAALQYAVDVKNV 250 Query 232 VIVAAAGNTGGA---AQCPPQAPGVTR----DSVTVAVSPAWYDDYVLTVGSVNAQGEPS 284 V+V AAGN G +Q PP P DSV VSPAWY+D VLTVGS+ G+PS Sbjct 251 VVVVAAGNVGDGQCKSQNPPPDPARPNTPDWDSVLETVSPAWYNDLVLTVGSIGPDGQPS 310 Query 285 AFTLAGPWVDVAATGEAVTSLSPFGDGTVNRLGGQHGSIPISGTSYAAPVVSGLAALIRA 344 F+L GPWVDV+A GE + SL P D N G G +PI GTS++APVVSG+ AL+R+ Sbjct 311 KFSLGGPWVDVSAPGEDIVSLDPNRDALTNAYMGDQGPVPIQGTSFSAPVVSGVVALVRS 370 Query 345 RFPTLTARQVMQRIESTAHHPPAGWDPLVGNGTVDALAAVSSD 387 RFP L+AR+VM RI++TAH PP GWDP +G G VDALAAVS D Sbjct 371 RFPQLSAREVMDRIKNTAHRPPGGWDPYLGFGVVDALAAVSDD 413 >gi|333991915|ref|YP_004524529.1| membrane-anchored serine protease (mycosin) MycP4 [Mycobacterium sp. JDM601] gi|333487883|gb|AEF37275.1| membrane-anchored serine protease (mycosin) MycP4 [Mycobacterium sp. JDM601] Length=439 Score = 352 bits (903), Expect = 8e-95, Method: Compositional matrix adjust. Identities = 222/357 (63%), Positives = 254/357 (72%), Gaps = 21/357 (5%) Query 51 TVQREVCTEVTAESGRAFGRAERSAQLADLDQVWRLTRGAGQRVAVIDTGVARHRRLPKV 110 TVQREVC T + + + DL VW LTRGAGQRVAVIDTGVA HRRLP + Sbjct 54 TVQREVCGVPTLQPDAPVTQLDG----LDLPAVWALTRGAGQRVAVIDTGVAPHRRLPGL 109 Query 111 VAGGDYVFTGDGTADCDAHGTLVAGIIAAAPDAQSDNFSGVAPDVTLISIRQSSSKFAPV 170 V GGDYV +GDG DCD HGTLVAGII AA D +D F+G+AP T+I IRQSS+KFA Sbjct 110 VGGGDYVSSGDGAQDCDGHGTLVAGIIGAAADPATDRFAGLAPLATVIGIRQSSAKFAAA 169 Query 171 GDPSSTGVGDVDTMAKAVRTAADLGASVINISSIACVPAAAAPDDRALGAALAYAVDVKN 230 + GVGDVDT+AKAVRTAADLG+SVINIS++AC+PA + DDRALGAALAYAV+V+N Sbjct 170 A--DAPGVGDVDTLAKAVRTAADLGSSVINISAVACLPAGSGLDDRALGAALAYAVEVRN 227 Query 231 AVIVAAAGNTGGAAQCPPQAPGVTRDSVTVAVSPAWYDDYVLTVGSVNAQGEPSAFTLAG 290 AV+VAAAGNT C P + V+PAWYDDYVLTVGSV+A G PSAFTLAG Sbjct 228 AVVVAAAGNTDDG--CGAGGPMI--------VTPAWYDDYVLTVGSVDAHGAPSAFTLAG 277 Query 291 PWVDVAATGEAVTSLSPFGDGTVNRLGGQHGSIPISGTSYAAPVVSGLAALIRARFPTLT 350 PWVDVAA GE V SLS D N + G P+ GTS+AAPVVSGLAALIRARFP T Sbjct 278 PWVDVAAPGEGVLSLSTIADAMANTVAGS----PVHGTSFAAPVVSGLAALIRARFPDWT 333 Query 351 ARQVMQRIESTAHHPPAGWDPLVGNGTVDALAAVSSDSI-PQAGTATSDPAPVAVPV 406 RQVM RI++TAHHPP G D +VG G +D LAAVS+D+ P AG PAP PV Sbjct 334 PRQVMDRIKATAHHPPGGRDDVVGAGVIDPLAAVSADTTRPAAGRPVPRPAPPGTPV 390 >gi|118467437|ref|YP_885916.1| subtilase [Mycobacterium smegmatis str. MC2 155] gi|118168724|gb|ABK69620.1| subtilase family protein [Mycobacterium smegmatis str. MC2 155] Length=442 Score = 344 bits (883), Expect = 1e-92, Method: Compositional matrix adjust. Identities = 223/387 (58%), Positives = 258/387 (67%), Gaps = 31/387 (8%) Query 80 LDQVWRLTRGAGQRVAVIDTGVARHRRLPKVVAGGDYVFTGDGTADCDAHGTLVAGIIAA 139 L+ VWRLTRG GQ VAVIDTGVARHR LP++V GGDYV GDGTADCD HGT+VAGII Sbjct 76 LEPVWRLTRGRGQVVAVIDTGVARHRWLPRLVGGGDYVSNGDGTADCDGHGTIVAGIIGG 135 Query 140 APDAQSDNFSGVAPDVTLISIRQSSSKFAPVGDPSSTGVGDVDTMAKAVRTAADLGASVI 199 A A D FSGVAP+ T+++IRQSS++FA D +GVGDV T+AKAVRTAADLGA+VI Sbjct 136 A--ATPDGFSGVAPEATILAIRQSSNRFAD--DAGGSGVGDVGTLAKAVRTAADLGATVI 191 Query 200 NISSIACVPAAAAP-------DDRALGAALAYAVDVKNAVIVAAAGNTGGAAQC----PP 248 NISS+ACV A DDR LGAALAYAV V+V AA GA QC P Sbjct 192 NISSVACVDADPDTDTADAGFDDRPLGAALAYAV-DVKNVVVVAAAGNVGAGQCRHQNPL 250 Query 249 QAPGVTRDSVTVAVSPAWYDDYVLTVGSVNAQGEPSAFTLAGPWVDVAATGEAVTSLSPF 308 APG D V SP WYDD VL VGSV A G S+F+LAGPWVD+AA GE V SL P Sbjct 251 DAPG--WDDVQSVTSPGWYDDLVLCVGSVAADGTASSFSLAGPWVDIAAPGEQVVSLHPD 308 Query 309 GDGTVNRLGGQHGSIPISGTSYAAPVVSGLAALIRARFPTLTARQVMQRIESTAHHPPAG 368 GDG + LG PISGTSYAAP V+G+AAL+R+RFP L+AR+VM+RIE+TA PP G Sbjct 309 GDGLIASLGADK---PISGTSYAAPFVAGVAALVRSRFPHLSAREVMRRIEATAVRPPRG 365 Query 369 WDPLVGNGTVDALAAVSSDSIPQAGTATSDPAPVAVPVPRRSTPGPSDRRALHTAFAGAA 428 WD VG+G VD LAAVS D+ P + A VA P P GP RR AF G A Sbjct 366 WDAAVGSGVVDPLAAVSGDA-PALAPPARNTAMVAPPAPSPEDTGP--RR---IAFGGGA 419 Query 429 ICLLALMATLATASRRLRPGRNGIAGD 455 +C+ +AT+ + R GR GI GD Sbjct 420 LCVAVALATVMLSRR----GRQGITGD 442 >gi|226305378|ref|YP_002765336.1| S8 family peptidase [Rhodococcus erythropolis PR4] gi|226184493|dbj|BAH32597.1| probable S8 family peptidase [Rhodococcus erythropolis PR4] Length=470 Score = 329 bits (843), Expect = 7e-88, Method: Compositional matrix adjust. Identities = 215/433 (50%), Positives = 263/433 (61%), Gaps = 23/433 (5%) Query 10 LVVSALATLSGLGTPVAHAVSPPPIDERWLPESALPAPPRPTVQREVCTEVTAESGRAFG 69 LV+ L L+G G A + P PID LPE PAPP+PT QR +C V A +G Sbjct 13 LVIVVLTVLAGAGG--ASSAVPSPIDPAMLPEDGPPAPPQPTEQRTLC--VPAVAGGDGA 68 Query 70 RAERSAQLADLDQVWRLTRGAGQRVAVIDTGVARHRRLPKVVAGGDYVFTGDGTADCDAH 129 RS Q D VW +TRGAGQR+AVIDTGV+RH RLP + GGDYV T DGT DCD+H Sbjct 69 DIPRSQQDLGFDSVWSITRGAGQRIAVIDTGVSRHPRLPALEGGGDYVGTSDGTDDCDSH 128 Query 130 GTLVAGIIAAAPDAQSDNFSGVAPDVTLISIRQSSSKFAPVG---DP----SSTGVGDVD 182 GT+VAG+IAA FSG APD +ISIRQSS+ F+ G DP +S+G G+VD Sbjct 129 GTVVAGLIAAE-QVDGSGFSGAAPDAQIISIRQSSAAFSVAGQREDPAVAENSSGYGNVD 187 Query 183 TMAKAVRTAADLGASVINISSIACVPAAAAPDDRALGAALAYAVDVK---NAVIVAAAGN 239 TMA AVR AADLGASVINIS +AC PA +D+ LGAA+ YA K G+ Sbjct 188 TMALAVRHAADLGASVINISEVACKPAGDGINDQRLGAAIEYATIAKNAVVVAAAGNVGS 247 Query 240 TGGAAQCPPQAPGVTR----DSVTVAVSPAWYDDYVLTVGSVNAQGEPSAFTLAGPWVDV 295 G Q PP P + +SVT SPAWYDDYVLTVGSV+ G S+F+L GPWVDV Sbjct 248 GGCKNQNPPPDPLDPQADPWNSVTTIASPAWYDDYVLTVGSVDPNGTASSFSLGGPWVDV 307 Query 296 AATGEAVTSLSPFGDGTVNRLGGQHGSIP-ISGTSYAAPVVSGLAALIRARFPTLTARQV 354 AA G + SL P G N + G G++ +GTS+AAP V+ AAL+R+ P LTA QV Sbjct 308 AAPGTGIISLHPTSPGLTNGVYGSDGAVQSFNGTSFAAPYVAATAALVRSVHPELTALQV 367 Query 355 MQRIESTAHHPPAGWDPLVGNGTVDALAAVSSDSIPQAGTATSDPAPVAVPVPRRSTPGP 414 MQRIE+TAH P GW+P VG+G +D LAAV+ + P + + P+P TP Sbjct 368 MQRIEATAHAPAQGWNPYVGHGVIDPLAAVTGELAPGERVKVNHQSVTIDPLP---TPPA 424 Query 415 SDRRALHTAFAGA 427 D R+ A GA Sbjct 425 PDNRSRDAALVGA 437 >gi|229489382|ref|ZP_04383245.1| peptidase S8 and S53, subtilisin, kexin, sedolisin [Rhodococcus erythropolis SK121] gi|229323479|gb|EEN89237.1| peptidase S8 and S53, subtilisin, kexin, sedolisin [Rhodococcus erythropolis SK121] Length=469 Score = 324 bits (831), Expect = 2e-86, Method: Compositional matrix adjust. Identities = 205/396 (52%), Positives = 251/396 (64%), Gaps = 20/396 (5%) Query 10 LVVSALATLSGLGTPVAHAVSPPPIDERWLPESALPAPPRPTVQREVCTEVTAESGRAFG 69 LV+ A + L+G G A + P PID LPE PAPP+PT QR +C V A +G Sbjct 12 LVIVAFSVLAGAGG--ASSAVPSPIDPAMLPEDGPPAPPQPTEQRTLC--VPAVAGGDGA 67 Query 70 RAERSAQLADLDQVWRLTRGAGQRVAVIDTGVARHRRLPKVVAGGDYVFTGDGTADCDAH 129 RS + D VW +TRGAGQR+AVIDTGV+RH RLP + GGDYV T DGT DCDAH Sbjct 68 DIPRSQRDLGFDSVWPITRGAGQRIAVIDTGVSRHPRLPSLDGGGDYVGTSDGTDDCDAH 127 Query 130 GTLVAGIIAAAPDAQSDNFSGVAPDVTLISIRQSSSKFAPVG---DP----SSTGVGDVD 182 GT+VAG+IAA + FSG APD +ISIRQSS+ F+ G DP +S+G G+VD Sbjct 128 GTVVAGLIAAQ-QVEGSGFSGAAPDAQIISIRQSSAAFSVAGQREDPAVAENSSGYGNVD 186 Query 183 TMAKAVRTAADLGASVINISSIACVPAAAAPDDRALGAALAYAVDVK---NAVIVAAAGN 239 TMA AVR AAD+GASVINIS +AC PA +D+ LGAA+ YA K G+ Sbjct 187 TMASAVRHAADMGASVINISEVACKPAGDGINDQRLGAAIEYATIAKNVVVVAAAGNVGS 246 Query 240 TGGAAQCPPQAP----GVTRDSVTVAVSPAWYDDYVLTVGSVNAQGEPSAFTLAGPWVDV 295 G Q PP P +SVT SPAWYDDYVLTVGSV+ G S+F+L GPWVDV Sbjct 247 GGCKNQNPPPDPVDPLADPWNSVTTIASPAWYDDYVLTVGSVDPNGAASSFSLGGPWVDV 306 Query 296 AATGEAVTSLSPFGDGTVNRLGGQHGSIP-ISGTSYAAPVVSGLAALIRARFPTLTARQV 354 AA G +TSL P G N + G G++ +GTS+AAP V+ AAL+R+ P LTA QV Sbjct 307 AAPGTGITSLHPTSPGLTNGVYGSDGAVQSFNGTSFAAPFVAATAALVRSVHPELTALQV 366 Query 355 MQRIESTAHHPPAGWDPLVGNGTVDALAAVSSDSIP 390 QRIE+TAH P GW+P VG+G +D LAAV+ + P Sbjct 367 TQRIEATAHAPAQGWNPYVGHGVIDPLAAVTGELAP 402 >gi|325675481|ref|ZP_08155165.1| serine protease [Rhodococcus equi ATCC 33707] gi|325553452|gb|EGD23130.1| serine protease [Rhodococcus equi ATCC 33707] Length=462 Score = 323 bits (828), Expect = 4e-86, Method: Compositional matrix adjust. Identities = 212/399 (54%), Positives = 259/399 (65%), Gaps = 20/399 (5%) Query 4 SRTLRLLVVSALATLSGLGTPVAHAVSPPPIDERWLPESALPAPPRPTVQREVCTEVTAE 63 +R ++ + A+ATLS G V AV P PID LP +A PAP PT QR C TA Sbjct 7 ARPATIISLLAVATLSLGG--VGSAVVPSPIDPGRLPGAARPAPLAPTEQRNACAVATAS 64 Query 64 SGRAFGRAERSAQLADLDQVWRLTRGAGQRVAVIDTGVARHRRLPKVVAGGDYVFTGDGT 123 + + D VW LTRGAGQ VAVIDTGVARH RLP ++ GGDYV TGDGT Sbjct 65 ADEP--NVPLPQRTMSFDTVWPLTRGAGQTVAVIDTGVARHPRLPGLIPGGDYVSTGDGT 122 Query 124 ADCDAHGTLVAGIIAAAPDAQSDNFSGVAPDVTLISIRQSSSKFAPV---GDP----SST 176 DCDAHGT+VAG+IAAAP S F+G APD +++IRQSS+ F+ DP +++ Sbjct 123 GDCDAHGTIVAGLIAAAPTPTS-GFAGGAPDARVMTIRQSSANFSETRRRDDPNDVQNTS 181 Query 177 GVGDVDTMAKAVRTAADLGASVINISSIACVPAAAAPDDRALGAALAYAVDVKNAVIVAA 236 G G+ TMA A+R A D GA+V+NIS +AC A+ D++LGAA+ YA VKNAV+VAA Sbjct 182 GYGNTQTMAMAIRQAVDNGATVVNISEVACRSASDGIADQSLGAAVHYAATVKNAVVVAA 241 Query 237 AGNT---GGAAQCP---PQAPGVT-RDSVTVAVSPAWYDDYVLTVGSVNAQGEPSAFTLA 289 AGN G AQ P P PG DSV +PAWYDDYVLTVGSV+ G S FTL Sbjct 242 AGNFRSGGCMAQNPGADPLDPGADPWDSVATIATPAWYDDYVLTVGSVDPDGAASEFTLG 301 Query 290 GPWVDVAATGEAVTSLSPFGDG-TVNRLGGQHGSIPISGTSYAAPVVSGLAALIRARFPT 348 GPWVDVAA G + SLSP G G T + GQ +P GTS+AAP+VS AL+RAR+P Sbjct 302 GPWVDVAAPGTGIVSLSPDGTGETRSWSNGQGQQMPFVGTSFAAPLVSATVALVRARYPQ 361 Query 349 LTARQVMQRIESTAHHPPAGWDPLVGNGTVDALAAVSSD 387 LTA+QV+ RIE+TAH P GW+P VG G VD +AAV++D Sbjct 362 LTAQQVIARIEATAHAPAEGWNPFVGRGVVDPVAAVTAD 400 >gi|312140881|ref|YP_004008217.1| esx cluster serine peptidase [Rhodococcus equi 103S] gi|311890220|emb|CBH49538.1| putative esx cluster secreted serine peptidase [Rhodococcus equi 103S] Length=463 Score = 323 bits (827), Expect = 5e-86, Method: Compositional matrix adjust. Identities = 209/399 (53%), Positives = 259/399 (65%), Gaps = 20/399 (5%) Query 4 SRTLRLLVVSALATLSGLGTPVAHAVSPPPIDERWLPESALPAPPRPTVQREVCTEVTAE 63 +R+ ++ + A+AT+S G V AV P PID LP +A PAP PT QR C T Sbjct 8 ARSATIVSLLAVATMSLGG--VGSAVVPSPIDPGRLPGAARPAPLAPTEQRNACAAATVS 65 Query 64 SGRAFGRAERSAQLADLDQVWRLTRGAGQRVAVIDTGVARHRRLPKVVAGGDYVFTGDGT 123 +G + D VW LTRGAGQ VAVIDTGVARH RLP ++ GGDYV TGDGT Sbjct 66 AGEP--NVPLPQRTMSFDTVWPLTRGAGQTVAVIDTGVARHPRLPGLIPGGDYVSTGDGT 123 Query 124 ADCDAHGTLVAGIIAAAPDAQSDNFSGVAPDVTLISIRQSSSKFAPV---GDP----SST 176 DCDAHGT+VAG+IAAAP + F+G APD +++IRQSS+ F+ DP +++ Sbjct 124 GDCDAHGTIVAGLIAAAP-TPTTGFAGGAPDARVMTIRQSSANFSETRRRDDPNDVQNTS 182 Query 177 GVGDVDTMAKAVRTAADLGASVINISSIACVPAAAAPDDRALGAALAYAVDVKNAVIVAA 236 G G+ TMA A+R A D GA+V+NIS +AC A+ D++LGAA+ YA VKNAV+VAA Sbjct 183 GYGNTQTMAMAIRQAVDNGATVVNISEVACRSASDGIADQSLGAAVHYAATVKNAVVVAA 242 Query 237 AGN--TGGA-AQCP---PQAPGVT-RDSVTVAVSPAWYDDYVLTVGSVNAQGEPSAFTLA 289 AGN +GG AQ P P PG DSV +PAWYDDYVLTVGSV+ G S FTL Sbjct 243 AGNFRSGGCMAQNPGADPLDPGADPWDSVATIATPAWYDDYVLTVGSVDPDGAASEFTLG 302 Query 290 GPWVDVAATGEAVTSLSPFGDGTVNRLGGQHG-SIPISGTSYAAPVVSGLAALIRARFPT 348 GPWVDVAA G + SLSP G G G +P GTS+AAP+VS AL+RAR+P Sbjct 303 GPWVDVAAPGTGIVSLSPDGAGETRSWSNSQGQQMPFVGTSFAAPLVSATVALVRARYPQ 362 Query 349 LTARQVMQRIESTAHHPPAGWDPLVGNGTVDALAAVSSD 387 LTA+QV+ RIE+TAH P GW+P VG G VD +AAV++D Sbjct 363 LTAQQVIARIEATAHAPAEGWNPFVGRGVVDPVAAVTAD 401 >gi|226365630|ref|YP_002783413.1| subtilisin family peptidase [Rhodococcus opacus B4] gi|226244120|dbj|BAH54468.1| subtilisin family peptidase [Rhodococcus opacus B4] Length=463 Score = 300 bits (769), Expect = 3e-79, Method: Compositional matrix adjust. Identities = 189/345 (55%), Positives = 226/345 (66%), Gaps = 22/345 (6%) Query 79 DLDQVWRLTRGAGQRVAVIDTGVARHRRLPKVVAGGDYVFTGDGTADCDAHGTLVAGIIA 138 D VW +TRGAGQ VAVIDTGV+RH RLP + GGD V T GT DCDAHGTLVAG+I Sbjct 73 DFQSVWPITRGAGQLVAVIDTGVSRHPRLPGLEDGGDLVGTETGTVDCDAHGTLVAGLIG 132 Query 139 AAPDAQSDNFSGVAPDVTLISIRQSSSKFAPVGDPSST--------GVGDVDTMAKAVRT 190 AA FSG APD ++SIRQSS+ ++PVG G G+V+TMA A+R Sbjct 133 AA-QVPGSGFSGGAPDSRIMSIRQSSTAYSPVGQADEIDNAGNTVGGYGNVETMATAIRR 191 Query 191 AADLGASVINISSIACVPAAAA--PDDRALGAALAYAVDVKNAVIVAAAGNTGGAAQCPP 248 AAD GA+VINIS +AC AA DR +GAA+ YAV V NAV+VAAAGN G + C Sbjct 192 AADRGATVINISEVACKTAAEGIGSSDRYVGAAVKYAVTVHNAVVVAAAGNFG-SGNCKI 250 Query 249 QAPGVT--------RDSVTVAVSPAWYDDYVLTVGSVNAQGEPSAFTLAGPWVDVAATGE 300 Q P V DSV+ SPAWYDDYVLTVGSV+A G PS F+LAGPWVDVAA G Sbjct 251 QNPPVDPLRPGADLSDSVSTIASPAWYDDYVLTVGSVDANGSPSNFSLAGPWVDVAAPGT 310 Query 301 AVTSLSPF-GDGTVNRLGGQHGSIPISGTSYAAPVVSGLAALIRARFPTLTARQVMQRIE 359 +TSL P GD T G + + P+ GTS+AAP VS AL+R+RFP L+ARQVM RIE Sbjct 311 GLTSLHPTTGDLTNTTYGAEGNAEPVQGTSFAAPYVSATVALVRSRFPQLSARQVMARIE 370 Query 360 STAHHPPAGWDPLVGNGTVDALAAVSSDSIPQAGTATSDPAPVAV 404 +TAH P GW+P VG+G +D LAAV++D +P G VA+ Sbjct 371 ATAHAPAEGWNPSVGHGIIDPLAAVTAD-VPLDGVTVDQSNSVAI 414 >gi|343925121|ref|ZP_08764653.1| putative S8 family peptidase [Gordonia alkanivorans NBRC 16433] gi|343765052|dbj|GAA11579.1| putative S8 family peptidase [Gordonia alkanivorans NBRC 16433] Length=465 Score = 298 bits (763), Expect = 1e-78, Method: Compositional matrix adjust. Identities = 197/382 (52%), Positives = 243/382 (64%), Gaps = 27/382 (7%) Query 26 AHAVSPPPIDERWLPESALPAPPRPTVQREVCTEVTAESGRAFGRAERSAQLADLDQVWR 85 A AV+PP +D L SA APP PT Q +C T A A +S + +L++ WR Sbjct 28 AAAVTPPRVDASALIRSAPVAPPEPTEQSHLCNTATLTRSTANPTAAQS--MMNLEEAWR 85 Query 86 LTRGAGQRVAVIDTGVARHRRLPKVVAGGDYVFTGDGTADCDAHGTLVAGIIAAAPDAQS 145 +RGAGQRVAVIDTGV H RL +V AGGDYV G G DCDAHGTLVAGIIAA P + S Sbjct 86 FSRGAGQRVAVIDTGVTPHPRLGRVTAGGDYVSGGSGLEDCDAHGTLVAGIIAARP-SSS 144 Query 146 DNFSGVAPDVTLISIRQSSSKFAPVGD-------PS-STGVGDVDTMAKAVRTAADLGAS 197 D F+GVAP ++I+IRQSSS F + PS +G G V T+A A+ A DL A+ Sbjct 145 DAFAGVAPAASIIAIRQSSSAFKAKNNRRGDDAAPSVGSGFGSVRTLAHAIVRAVDLRAT 204 Query 198 VINISSIACVPAAAAPDDRALGAALAYAVDVKNAVIVAAAGNTGGAAQCPPQAP----GV 253 VINIS +AC +AA DDRALGAA+ YA D ++ V+VAAAGN C Q P G Sbjct 205 VINISEVACASSAAKVDDRALGAAIRYAYD-RDVVVVAAAGNVTRDGACRSQNPAPAAGN 263 Query 254 TRD--SVTVAVSPAWYDDYVLTVGSVN-AQGEPSAFTLAGPWVDVAATGEAVTSL-SPFG 309 D SV+ SPAWY YVLTVG+V+ A G PS F+L GPWV VAA G + SL S G Sbjct 264 PDDWSSVSTVASPAWYSPYVLTVGAVDAASGRPSEFSLHGPWVGVAAPGTDIVSLDSARG 323 Query 310 DGTVNRL----GGQHGSIPISGTSYAAPVVSGLAALIRARFPTLTARQVMQRIESTAHHP 365 NRL + G +P+ GTS+AAP V+G AAL+RARFP L+AR+VM RI STAH P Sbjct 324 S---NRLVSAQTAEEGPLPLIGTSFAAPYVAGTAALVRARFPGLSAREVMDRITSTAHSP 380 Query 366 PAGWDPLVGNGTVDALAAVSSD 387 G D +G+G VD +AA++++ Sbjct 381 GTGHDQRIGHGVVDPVAALTAE 402 >gi|169629311|ref|YP_001702960.1| peptidase [Mycobacterium abscessus ATCC 19977] gi|169241278|emb|CAM62306.1| Probable peptidase [Mycobacterium abscessus] Length=461 Score = 294 bits (752), Expect = 3e-77, Method: Compositional matrix adjust. Identities = 216/466 (47%), Positives = 277/466 (60%), Gaps = 49/466 (10%) Query 5 RTLRLLVVSALATLSGLGTPVAHAVSPPPIDERWLPESALPAPPRPTVQREVCTEV---- 60 R L +V + L LS + PVA AV P D LP+ + P+ +Q C+ Sbjct 13 RALGGVVAATLLALSPVAAPVAGAVIQPEADPAALPKDSSPSA-TAGMQSSACSTTVLLP 71 Query 61 -TAESGRAFGRAERSAQLADLDQVWRLTRGAGQRVAVIDTGVARHRRLPKVVAGGDYVFT 119 T SG+ + ++ WR +RG GQ VA+IDTGV RL V GGDYV + Sbjct 72 GTGTSGKPS---------PEFEEAWRFSRGEGQSVAIIDTGVKPSARL-HVEPGGDYVQS 121 Query 120 GDGTADCDAHGTLVAGIIAAAPDAQSDNFSGVAPDVTLISIRQSSSKFAPV----GDPSS 175 DG DCD HGT+VAGII A P D FSG+AP LISIRQ SSKF+P GDPS+ Sbjct 122 TDGLTDCDGHGTMVAGIIGAQPG--PDGFSGIAPAAKLISIRQESSKFSPRLTAGGDPST 179 Query 176 TGVGD-VDTMAKAVRTAADLGASVINISSIACVPAAAAPDDRALGAALAYAVDVKNAVIV 234 V+T+A+++ AA+LGA VINISS CVPAA D ALGAAL YAV K+AV+V Sbjct 180 NAATQYVNTLARSIVHAANLGARVINISSAECVPAAKPIDQAALGAALRYAVAEKDAVVV 239 Query 235 AAAGNT-GGAAQC-----------PPQAPGVTRDSVTVAVSPAWYDDYVLTVGSVNAQGE 282 AAAGNT GG+A C P GV +SV+V P+W+ YVL+VGSV G Sbjct 240 AAAGNTSGGSANCQQNPLTGSGADPRNWSGV--ESVSV---PSWWQPYVLSVGSVGIDGS 294 Query 283 PSAFTLAGPWVDVAATGEAVTSLSPFGDGTV-NRLGGQHGS-IPISGTSYAAPVVSGLAA 340 PS FT+AGPWV +AA GE VTSLS +G + N + GQ+G +P+ GTSYA V+G+AA Sbjct 295 PSKFTMAGPWVGIAANGENVTSLSNDAEGGLANGMIGQNGKPVPLFGTSYATAYVAGVAA 354 Query 341 LIRARFPTLTARQVMQRIESTAHHPPAGWDP--LVGNGTVDALAAVSSDSIPQAGTATSD 398 L+R+R+P LTA QV+ R++ TA AG P LVG GTVD +AA++ + +P G A+S Sbjct 355 LVRSRYPELTAPQVISRLQRTARD--AGRSPSNLVGAGTVDPVAALTWE-VPADGNASSG 411 Query 399 PAPVAVPVPRRSTPGPSDRRALHTAFAGAAICLLALMATLATASRR 444 P AV P TP R L AF GA +CL+A++ A ++RR Sbjct 412 PGARAVVPPPPPTPENPLPRRL--AFLGAGVCLIAVVVVAALSARR 455 >gi|54022816|ref|YP_117058.1| putative protease [Nocardia farcinica IFM 10152] gi|54014324|dbj|BAD55694.1| putative protease [Nocardia farcinica IFM 10152] Length=455 Score = 293 bits (750), Expect = 4e-77, Method: Compositional matrix adjust. Identities = 190/419 (46%), Positives = 256/419 (62%), Gaps = 46/419 (10%) Query 25 VAHAVSPPPIDERWLPESALPAPPRPTVQ--REVCTEV-TAESGRAFGRAERSAQLADLD 81 VAHA PP ++ P APP T + C ++ T G A+R+ DL+ Sbjct 13 VAHADRPPAVNPGLKPPGDPAAPPEKTERPANSACADILTGGDGPTIPEAQRAL---DLE 69 Query 82 QVWRLTRGAGQRVAVIDTGVARHRRLPKVVAGGDYV-FTGDGTADCDAHGTLVAGIIAAA 140 + W+ ++GAGQRVAVIDTGVARH RLP + AGGD+V +GDGT DCD HGTLVAGIIAA+ Sbjct 70 RAWKFSKGAGQRVAVIDTGVARHPRLPGLEAGGDFVANSGDGTEDCDGHGTLVAGIIAAS 129 Query 141 PDAQSDNFSGVAPDVTLISIRQSSSKFAPVG-------DPSSTGVGDVDTMAKAVRTAAD 193 + F+GVAP+ +I+IRQ+S + G D G+++TMA A+ AAD Sbjct 130 -QVEGQGFAGVAPEAQIITIRQTSKMYQKEGRSAEKAPDEFPDSYGNLNTMASAIVRAAD 188 Query 194 LGASVINISSIACVPAAAAPD-DRALGAALAYAVDVKNAVIVAAAGNT-----GGAAQCP 247 LGA+VINIS + C +PD D +GAAL YA K+ V+V AAGN G Sbjct 189 LGATVINISEVWC--GTGSPDADNKVGAALHYAAIEKDVVVVVAAGNKDDKCKGENQVID 246 Query 248 PQAPGVTRD---SVTVAVSPAWYDDYVLTVGSVNAQGEPSAFTLAGPWVDVAATGEAVTS 304 P P T D VT +SPA +DDYVL+VGS++A G PS+FT+ GPW+ VAA+GE + S Sbjct 247 PLDP--TADPWSKVTYNISPARWDDYVLSVGSIDANGAPSSFTIPGPWLGVAASGENMVS 304 Query 305 LSPFGDGT---VNRLGGQHGSIPISGTSYAAPVVSGLAALIRARFPTLTARQVMQRIEST 361 L P G GT V GQ G++ SGTS+A P+V+G+AAL+RARFP L+A +V++RI++T Sbjct 305 LDPRGTGTAIGVVDQRGQQGAV--SGTSFATPIVAGVAALVRARFPELSALEVIKRIQAT 362 Query 362 AHHPPAGWDPLVGNGTVDALAAVSSDSIPQAGTATSDPAPVAVPVPRRSTPGPSDRRAL 420 AH P GW+P +G G VD +AA+ ++ P +P P+R TP S + A+ Sbjct 363 AHAPAEGWNPYIGYGAVDPIAAL------------TNAVPGELP-PKRPTPAKSRQLAV 408 >gi|54022795|ref|YP_117037.1| putative protease [Nocardia farcinica IFM 10152] gi|54014303|dbj|BAD55673.1| putative protease [Nocardia farcinica IFM 10152] Length=480 Score = 292 bits (748), Expect = 8e-77, Method: Compositional matrix adjust. Identities = 191/408 (47%), Positives = 241/408 (60%), Gaps = 19/408 (4%) Query 26 AHAVSPPPIDERWLPE----SALPAPPRPTVQREVCTEVTAESGRAFGRAERSAQLADLD 81 A A+ PP +D+ L S PAP PT QR VC E +G + + DL Sbjct 31 AAAIGPPVVDDGALGAALAISGRPAPLEPTEQRSVCAEPIL-TGAPPVEPPLAQAVLDLP 89 Query 82 QVWRLTRGAGQRVAVIDTGVARHRRLPKVVAGGDYVFTGDGTADCDAHGTLVAGIIAAAP 141 W+ +RGAGQ+VAVIDTGV RH RL + AGGDYV DGT DCD HGTLVAGIIAAAP Sbjct 90 TAWQFSRGAGQKVAVIDTGVNRHPRLRALQAGGDYVADTDGTVDCDGHGTLVAGIIAAAP 149 Query 142 DAQSDNFSGVAPDVTLISIRQSSSKFAPV--------GDPSSTGVGDVDTMAKAVRTAAD 193 + D F+GVAPD +++IRQ S + P G +++G G+V T+A AV A D Sbjct 150 -SPDDAFAGVAPDAEILAIRQLSLAYEPKDRRSGEQSGAITTSGYGNVLTLAGAVVRAVD 208 Query 194 LGASVINISSIACVPAAAAPDDRALGAALAYAVDVKNAVIVAAAGNTGGAAQCPPQAPGV 253 +GA+VINIS +AC A A P+D ALGAA+ YA D +N V+VAAAGN C Q Sbjct 209 MGATVINISEVACSAAGATPEDAALGAAVKYAFD-RNVVVVAAAGNLTSEGACKTQNERP 267 Query 254 TRDSVTVAVSPAWYDDYVLTVGSVNAQGEPSAFTLAGPWVDVAATGEAVTSL--SPFGDG 311 SV SPAW+D YVL+V S++ G S +L GPWV AA G + SL P G Sbjct 268 GWSSVQTVASPAWFDPYVLSVASIDPNGMVSELSLHGPWVRAAAIGRRIVSLDSKPGATG 327 Query 312 TVNRLGGQHGSIPISGTSYAAPVVSGLAALIRARFPTLTARQVMQRIESTAHHPPAGWDP 371 V+ + G PI GTS+AAP VSGL AL+RARFP L A QV+ R+ TAH P G D Sbjct 328 LVDGVQTSEGISPIEGTSFAAPYVSGLVALVRARFPELNAAQVIDRVVRTAHAPGTGRDD 387 Query 372 LVGNGTVDALAAVSSDSIPQAGTATSD-PAPVAVPVPRRSTPGPSDRR 418 +G+G +D +AA++++ Q A +D P P+A P R P P RR Sbjct 388 KLGHGLIDPVAALTAELPDQPVHAGADTPRPLAEPA-RPPGPDPLPRR 434 >gi|333921710|ref|YP_004495291.1| serine protease [Amycolicicoccus subflavus DQS3-9A1] gi|333483931|gb|AEF42491.1| Serine protease [Amycolicicoccus subflavus DQS3-9A1] Length=378 Score = 284 bits (727), Expect = 2e-74, Method: Compositional matrix adjust. Identities = 178/312 (58%), Positives = 214/312 (69%), Gaps = 17/312 (5%) Query 96 VIDTGVARHRRLPKVVAGGDYVFTGDGTADCDAHGTLVAGIIAAAPDAQSDNFSGVAPDV 155 +IDTGV H RL +V+ GGDYV GDGT DCDAHGT VAG+IAA PD+ SD+F+GVAP Sbjct 1 MIDTGVTPHPRLGEVIPGGDYVSFGDGTDDCDAHGTFVAGLIAARPDS-SDDFAGVAPRA 59 Query 156 TLISIRQSSSKFA-----PVGDPSSTGVGDVDTMAKAVRTAADLGASVINISSIACVPAA 210 +++IRQSS KFA P S G+V T+A AVR AADLGA+VIN+S + C PA Sbjct 60 QIVAIRQSSLKFARAASTPGEYQSENSYGNVRTLAMAVRRAADLGATVINVSEVGCSPAG 119 Query 211 AAPDDRALGAALAYAVDVKNAVIVAAAGNTGGAAQCPPQAPG-------VTRDSVTVAV- 262 + DDR LGAAL YAVDVK+AV+VAAAGN ++ C Q PG T D + +A Sbjct 120 ESLDDRELGAALRYAVDVKDAVVVAAAGNVNASSSCRDQNPGPDPRNASRTPDWLGIATV 179 Query 263 -SPAWYDDYVLTVGSVNAQGEPSAFTLAGPWVDVAATGEAVTSL--SPFGDGTVNRLGGQ 319 +PAWYDDYVLTVGSV++ G+PSAFTL GPWVDVAA G + SL P G G VN Sbjct 180 ATPAWYDDYVLTVGSVDSDGQPSAFTLGGPWVDVAAPGTGIVSLDAQPGGTGLVNATSHG 239 Query 320 HGSIPISGTSYAAPVVSGLAALIRARFPTLTARQVMQRIESTAHHPPAGWDPLVGNGTVD 379 PI+GTSYAAP SG AL+RARFP L+ARQ M RI +TAH P GWDP VG G +D Sbjct 240 EAVTPIAGTSYAAPYASGTVALVRARFPHLSARQTMDRIIATAHPPAHGWDPYVGFGVID 299 Query 380 ALAAVSSDSIPQ 391 +AAV++D P+ Sbjct 300 PVAAVTADLDPE 311 >gi|118469114|ref|YP_885035.1| subtilase [Mycobacterium smegmatis str. MC2 155] gi|118170401|gb|ABK71297.1| subtilase family protein [Mycobacterium smegmatis str. MC2 155] Length=459 Score = 283 bits (723), Expect = 5e-74, Method: Compositional matrix adjust. Identities = 181/400 (46%), Positives = 240/400 (60%), Gaps = 21/400 (5%) Query 5 RTLRLLVVSALATLSGLGTPVAHAVSPPPIDERWLPESALPAPPRPTVQREVCTEVTAES 64 ++L ++ + L L +G P A AVSPP +D + P P +P +QR C + Sbjct 4 KSLGVVATAGLVLL--IGCPSAGAVSPPQVDPQIAPPPGTAGPAQPMMQRSECITTSVLP 61 Query 65 GRAFGRAERSAQLADLDQVWRLTRGAGQRVAVIDTGVARHRRLPKVVAGGDYVFTGDGTA 124 G G + +L W+ +RGAGQ VAVIDTGV RLP V AGGDY+ + DG Sbjct 62 GTDPGAVSPNQLALNLSGAWQHSRGAGQTVAVIDTGVQPGPRLPNVEAGGDYIESTDGLT 121 Query 125 DCDAHGTLVAGIIAAAPDAQSDNFSGVAPDVTLISIRQSSSKFAP----VGDPSSTGVGD 180 DCD HGT VAG+IA P D FSGVAP+ LISIRQ+S +FAP ++ D Sbjct 122 DCDGHGTSVAGLIAGQPG--PDGFSGVAPEARLISIRQNSPRFAPRTPGADSEATRAASD 179 Query 181 VDTMAKAVRTAADLGASVINISSIACVPAAAAPDDRALGAALAYAVDVKNAVIVAAAGNT 240 +T+A+AV AAD+GA VINIS + C+PA D LGAAL YA K+AVIVAAAGN Sbjct 180 AETLARAVVRAADMGARVINISLVTCLPADRTIDQSVLGAALRYAALEKDAVIVAAAGNN 239 Query 241 GG----AAQC-----PPQAPGVTR--DSVTVAVSPAWYDDYVLTVGSVNAQGEPSAFTLA 289 G A C P PG R + VT P+W+ YVL+VG+V++ G+PS+FT+A Sbjct 240 RGGVSTGAACESNPLPSGTPGDPRNWNGVTSVSIPSWWQPYVLSVGAVDSTGQPSSFTMA 299 Query 290 GPWVDVAATGEAVTSLSPFGDGTV-NRLGGQHGS-IPISGTSYAAPVVSGLAALIRARFP 347 GPWV +AA GE + S+S DG + N L + +P++GTSYAA VSG+AAL+R++FP Sbjct 300 GPWVGIAAPGENIVSVSNAPDGGLSNALPSERDRLVPLTGTSYAAAYVSGVAALVRSKFP 359 Query 348 TLTARQVMQRIESTAHHPPAGWDPLVGNGTVDALAAVSSD 387 LTARQV+ R+ +TA L+G G VD +AA++ D Sbjct 360 DLTARQVVHRLTTTAQGAARSPSNLIGAGMVDPVAALTWD 399 >gi|339299876|gb|AEJ51986.1| membrane-anchored mycosin mycP4 [Mycobacterium tuberculosis CCDC5180] Length=143 Score = 280 bits (715), Expect = 5e-73, Method: Compositional matrix adjust. Identities = 142/143 (99%), Positives = 143/143 (100%), Gaps = 0/143 (0%) Query 313 VNRLGGQHGSIPISGTSYAAPVVSGLAALIRARFPTLTARQVMQRIESTAHHPPAGWDPL 372 +NRLGGQHGSIPISGTSYAAPVVSGLAALIRARFPTLTARQVMQRIESTAHHPPAGWDPL Sbjct 1 MNRLGGQHGSIPISGTSYAAPVVSGLAALIRARFPTLTARQVMQRIESTAHHPPAGWDPL 60 Query 373 VGNGTVDALAAVSSDSIPQAGTATSDPAPVAVPVPRRSTPGPSDRRALHTAFAGAAICLL 432 VGNGTVDALAAVSSDSIPQAGTATSDPAPVAVPVPRRSTPGPSDRRALHTAFAGAAICLL Sbjct 61 VGNGTVDALAAVSSDSIPQAGTATSDPAPVAVPVPRRSTPGPSDRRALHTAFAGAAICLL 120 Query 433 ALMATLATASRRLRPGRNGIAGD 455 ALMATLATASRRLRPGRNGIAGD Sbjct 121 ALMATLATASRRLRPGRNGIAGD 143 >gi|167967142|ref|ZP_02549419.1| membrane-anchored mycosin mycP3 [Mycobacterium tuberculosis H37Ra] Length=461 Score = 271 bits (692), Expect = 2e-70, Method: Compositional matrix adjust. Identities = 197/462 (43%), Positives = 260/462 (57%), Gaps = 37/462 (8%) Query 12 VSALATLSGLGTPVAHAVSPPPIDERWLPESALPAPPRPTVQREVCTEVTAESGRAFGRA 71 ++A ++G TP A A+ PP +D P S P P P QR C+ G G Sbjct 9 LAATVVVAGWWTPPAWAIGPPVVDAAAQPPSGDPGPVAPMEQRGACSVSGVIPGTDAGVP 68 Query 72 ERSAQLADLDQVWRLTRGAGQRVAVIDTGVARHRRLPKVVAGGDYVFTGDGTADCDAHGT 131 S + +L W+ +RG GQ VA+IDTGV RLP V AGGD+V + DG DCD HGT Sbjct 69 TPSQTMLNLPAAWQFSRGEGQLVAIIDTGVQPGPRLPNVDAGGDFVESTDGLTDCDGHGT 128 Query 132 LVAGIIAAAPDAQSDNFSGVAPDVTLISIRQSSSKFAPV---GDPS-STGVGDVDTMAKA 187 LVAGI+A P +D FSGVAP L+SIR S+KF+P GDP + DV +A A Sbjct 129 LVAGIVAGQPG--NDGFSGVAPAARLLSIRAMSTKFSPRTSGGDPQLAQATLDVAVLAGA 186 Query 188 VRTAADLGASVINISSIACVPAAAAPDDRALGAALAYAVDVKNAVIVAAAGNTGG----A 243 + AADLGA VIN+S+I C+PA D ALGAA+ YA K+AVIVAAAGNTG + Sbjct 187 IVHAADLGAKVINVSTITCLPADRMVDQAALGAAIRYAAVDKDAVIVAAAGNTGASGSVS 246 Query 244 AQC-------------PPQAPGVTRDSVTVAVSPAWYDDYVLTVGSVNAQGEPSAFTLAG 290 A C P GVT S+ P+W+ YVL+V S+ + G+PS F++ G Sbjct 247 ASCDSNPLTDLSRPDDPRNWAGVTSVSI-----PSWWQPYVLSVASLTSAGQPSKFSMPG 301 Query 291 PWVDVAATGEAVTSLSPFGDGTV-NRLGGQHGS-IPISGTSYAAPVVSGLAALIRARFPT 348 PWV +AA GE + S+S GDG + N L H + +SGTSYAA VSG+AAL+R+R+P Sbjct 302 PWVGIAAPGENIASVSNSGDGALANGLPDAHQKLVALSGTSYAAGYVSGVAALVRSRYPG 361 Query 349 LTARQVMQRIESTAHHPPAGWDPLVGNGTVDALAAVSSDSIPQAGTATSDPAPVAVPVPR 408 L A +V++R+ +TAH +VG G +DA+AA++ +P + PA P Sbjct 362 LNATEVVRRLTATAHRGARESSNIVGAGNLDAVAALTWQ-LPAEPGGGAAPAKPVADPPV 420 Query 409 RSTPGPSDRRALHTAFAGAAI--CLLALM-ATLATASRRLRP 447 + D + AFAGAA L+ L AT+A A RR P Sbjct 421 PAP---KDTTPRNVAFAGAAALSVLVGLTAATVAIARRRREP 459 >gi|15607432|ref|NP_214805.1| membrane-anchored mycosin [Mycobacterium tuberculosis H37Rv] gi|31791470|ref|NP_853963.1| protease precursor [Mycobacterium bovis AF2122/97] gi|121636206|ref|YP_976429.1| putative protease precursor [Mycobacterium bovis BCG str. Pasteur 1173P2] 65 more sequence titles Length=461 Score = 271 bits (692), Expect = 2e-70, Method: Compositional matrix adjust. Identities = 197/462 (43%), Positives = 260/462 (57%), Gaps = 37/462 (8%) Query 12 VSALATLSGLGTPVAHAVSPPPIDERWLPESALPAPPRPTVQREVCTEVTAESGRAFGRA 71 ++A ++G TP A A+ PP +D P S P P P QR C+ G G Sbjct 9 LAATVVVAGWWTPPAWAIGPPVVDAAAQPPSGDPGPVAPMEQRGACSVSGVIPGTDPGVP 68 Query 72 ERSAQLADLDQVWRLTRGAGQRVAVIDTGVARHRRLPKVVAGGDYVFTGDGTADCDAHGT 131 S + +L W+ +RG GQ VA+IDTGV RLP V AGGD+V + DG DCD HGT Sbjct 69 TPSQTMLNLPAAWQFSRGEGQLVAIIDTGVQPGPRLPNVDAGGDFVESTDGLTDCDGHGT 128 Query 132 LVAGIIAAAPDAQSDNFSGVAPDVTLISIRQSSSKFAPV---GDPS-STGVGDVDTMAKA 187 LVAGI+A P +D FSGVAP L+SIR S+KF+P GDP + DV +A A Sbjct 129 LVAGIVAGQPG--NDGFSGVAPAARLLSIRAMSTKFSPRTSGGDPQLAQATLDVAVLAGA 186 Query 188 VRTAADLGASVINISSIACVPAAAAPDDRALGAALAYAVDVKNAVIVAAAGNTGG----A 243 + AADLGA VIN+S+I C+PA D ALGAA+ YA K+AVIVAAAGNTG + Sbjct 187 IVHAADLGAKVINVSTITCLPADRMVDQAALGAAIRYAAVDKDAVIVAAAGNTGASGSVS 246 Query 244 AQC-------------PPQAPGVTRDSVTVAVSPAWYDDYVLTVGSVNAQGEPSAFTLAG 290 A C P GVT S+ P+W+ YVL+V S+ + G+PS F++ G Sbjct 247 ASCDSNPLTDLSRPDDPRNWAGVTSVSI-----PSWWQPYVLSVASLTSAGQPSKFSMPG 301 Query 291 PWVDVAATGEAVTSLSPFGDGTV-NRLGGQHGS-IPISGTSYAAPVVSGLAALIRARFPT 348 PWV +AA GE + S+S GDG + N L H + +SGTSYAA VSG+AAL+R+R+P Sbjct 302 PWVGIAAPGENIASVSNSGDGALANGLPDAHQKLVALSGTSYAAGYVSGVAALVRSRYPG 361 Query 349 LTARQVMQRIESTAHHPPAGWDPLVGNGTVDALAAVSSDSIPQAGTATSDPAPVAVPVPR 408 L A +V++R+ +TAH +VG G +DA+AA++ +P + PA P Sbjct 362 LNATEVVRRLTATAHRGARESSNIVGAGNLDAVAALTWQ-LPAEPGGGAAPAKPVADPPV 420 Query 409 RSTPGPSDRRALHTAFAGAAI--CLLALM-ATLATASRRLRP 447 + D + AFAGAA L+ L AT+A A RR P Sbjct 421 PAP---KDTTPRNVAFAGAAALSVLVGLTAATVAIARRRREP 459 >gi|108797360|ref|YP_637557.1| peptidase S8/S53 subtilisin kexin sedolisin [Mycobacterium sp. MCS] gi|119866444|ref|YP_936396.1| peptidase S8/S53 subtilisin kexin sedolisin [Mycobacterium sp. KMS] gi|126432981|ref|YP_001068672.1| peptidase S8/S53 subtilisin kexin sedolisin [Mycobacterium sp. JLS] gi|108767779|gb|ABG06501.1| peptidase S8 and S53, subtilisin, kexin, sedolisin [Mycobacterium sp. MCS] gi|119692533|gb|ABL89606.1| peptidase S8 and S53, subtilisin, kexin, sedolisin [Mycobacterium sp. KMS] gi|126232781|gb|ABN96181.1| peptidase S8 and S53, subtilisin, kexin, sedolisin [Mycobacterium sp. JLS] Length=461 Score = 270 bits (691), Expect = 3e-70, Method: Compositional matrix adjust. Identities = 175/374 (47%), Positives = 226/374 (61%), Gaps = 20/374 (5%) Query 30 SPPPIDERWLPESALPAPPRPTVQREVCTEVTAESGRAFGRAERSAQLADLDQVWRLTRG 89 +PP +D P S P +P QR C +G G + +L WR +RG Sbjct 26 TPPQVDPATPPPSGTAGPVQPMAQRGDCVVGGVLAGSDPGAVSPNQLALNLSGAWRHSRG 85 Query 90 AGQRVAVIDTGVARHRRLPKVVAGGDYVFTGDGTADCDAHGTLVAGIIAAAPDAQSDNFS 149 GQ VAVIDTGV RLP V GGD++ + DG DCD HGTLVAG+IA P A D FS Sbjct 86 EGQTVAVIDTGVKPGPRLPNVEPGGDFLGSTDGLTDCDGHGTLVAGLIAGQPGA--DGFS 143 Query 150 GVAPDVTLISIRQSSSKFAPVG---DPS-STGVGDVDTMAKAVRTAADLGASVINISSIA 205 GVAP ++SIRQ+S +F+PV DP+ S DV ++A+AV AADLGA VINIS ++ Sbjct 144 GVAPGARIVSIRQNSPRFSPVNPGEDPAVSRAAADVASLARAVVRAADLGARVINISVVS 203 Query 206 CVPAAAAPDDRALGAALAYAVDVKNAVIVAAAG------NTGGAAQCPPQAPGVTRDS-- 257 C+PA + D LGAAL YA K+AVIVAAAG NTG A + P D Sbjct 204 CLPAGRSVDQTELGAALRYAAREKDAVIVAAAGNDRAGMNTGSACESNPPGDAARPDDPR 263 Query 258 ----VTVAVSPAWYDDYVLTVGSVNAQGEPSAFTLAGPWVDVAATGEAVTSLSPFGDGTV 313 VT P+W+ YVL+VGS+ + G+PS FT++GPWV +AA GE +TS+S DG + Sbjct 264 NWAGVTSVSIPSWWQPYVLSVGSLTSTGQPSDFTMSGPWVGIAAPGENITSVSNGPDGGL 323 Query 314 -NRLGGQHGSI-PISGTSYAAPVVSGLAALIRARFPTLTARQVMQRIESTAHHPPAGWDP 371 N L + P+SGTSYAA VSG+AAL+R+RFP LTA QV+ R+ +TAH P Sbjct 324 ANGLPNDRDELFPVSGTSYAAAYVSGVAALVRSRFPELTAEQVVARLTATAHGGPRSPSN 383 Query 372 LVGNGTVDALAAVS 385 +VG G+VD +AA++ Sbjct 384 VVGAGSVDPVAALT 397 >gi|339293349|gb|AEJ45460.1| membrane-anchored mycosin mycP3 [Mycobacterium tuberculosis CCDC5079] gi|339296996|gb|AEJ49106.1| membrane-anchored mycosin mycP3 [Mycobacterium tuberculosis CCDC5180] Length=466 Score = 270 bits (691), Expect = 3e-70, Method: Compositional matrix adjust. Identities = 199/475 (42%), Positives = 264/475 (56%), Gaps = 39/475 (8%) Query 1 MTTSRTLR--LLVVSALATLSGLGTPVAHAVSPPPIDERWLPESALPAPPRPTVQREVCT 58 M + +R ++A ++G TP A A+ PP +D P S P P P QR C+ Sbjct 1 MGAQQMIRAAFACLAATVVVAGWWTPPAWAIGPPVVDAAAQPPSGDPGPVAPMEQRGACS 60 Query 59 EVTAESGRAFGRAERSAQLADLDQVWRLTRGAGQRVAVIDTGVARHRRLPKVVAGGDYVF 118 G G S + +L W+ +RG GQ VA+IDTGV RLP V AGGD+V Sbjct 61 VSGVIPGTDPGVPTPSQTMLNLPAAWQFSRGEGQLVAIIDTGVQPGPRLPNVDAGGDFVE 120 Query 119 TGDGTADCDAHGTLVAGIIAAAPDAQSDNFSGVAPDVTLISIRQSSSKFAPV---GDPS- 174 + DG DCD HGTLVAGI+A P +D FSGVAP L+SIR S+KF+P GDP Sbjct 121 STDGLTDCDGHGTLVAGIVAGQPG--NDGFSGVAPAARLLSIRAMSTKFSPRTSGGDPQL 178 Query 175 STGVGDVDTMAKAVRTAADLGASVINISSIACVPAAAAPDDRALGAALAYAVDVKNAVIV 234 + DV +A A+ AADLGA VIN+S+I C+PA D ALGAA+ YA K+AVIV Sbjct 179 AQATLDVAVLAGAIVHAADLGAKVINVSTITCLPADRMVDQAALGAAIRYAAVDKDAVIV 238 Query 235 AAAGNTGG----AAQC-------------PPQAPGVTRDSVTVAVSPAWYDDYVLTVGSV 277 AAAGNTG +A C P GVT S+ P+W+ YVL+V S+ Sbjct 239 AAAGNTGASGSVSASCDSNPLTDLSRPDDPRNWAGVTSVSI-----PSWWQPYVLSVASL 293 Query 278 NAQGEPSAFTLAGPWVDVAATGEAVTSLSPFGDGTV-NRLGGQHGS-IPISGTSYAAPVV 335 + G+PS F++ GPWV +AA GE + S+S GDG + N L H + +SGTSYAA V Sbjct 294 TSAGQPSKFSMPGPWVGIAAPGENIASVSNSGDGALANGLPDAHQKLVALSGTSYAAGYV 353 Query 336 SGLAALIRARFPTLTARQVMQRIESTAHHPPAGWDPLVGNGTVDALAAVSSDSIPQAGTA 395 SG+AAL+R+R+P L A +V++R+ +TAH +VG G +DA+AA++ +P Sbjct 354 SGVAALVRSRYPGLNATEVVRRLTATAHRGARESSNIVGAGNLDAVAALTWQ-LPAEPGG 412 Query 396 TSDPAPVAVPVPRRSTPGPSDRRALHTAFAGAAI--CLLALM-ATLATASRRLRP 447 + PA P + D + AFAGAA L+ L AT+A A RR P Sbjct 413 GAAPAKPVADPPVPAP---KDTTPRNVAFAGAAALSVLVGLTAATVAIARRRREP 464 >gi|326381856|ref|ZP_08203549.1| peptidase S8/S53 subtilisin kexin sedolisin [Gordonia neofelifaecis NRRL B-59395] gi|326199282|gb|EGD56463.1| peptidase S8/S53 subtilisin kexin sedolisin [Gordonia neofelifaecis NRRL B-59395] Length=439 Score = 270 bits (690), Expect = 3e-70, Method: Compositional matrix adjust. Identities = 189/376 (51%), Positives = 230/376 (62%), Gaps = 30/376 (7%) Query 46 APPRPTVQREVCTEVTAESGRAFGRAE-RSAQLADLDQVWRLTRGAGQRVAVIDTGVARH 104 AP T QR C A A R E +L D+ RL+RGAG RVAVIDTGVA H Sbjct 42 APLEETEQRANC----AVGVDAVSREEPLGHRLLDVRAAHRLSRGAGVRVAVIDTGVAPH 97 Query 105 RRLPKVVAGGDYVFTGDGTADCDAHGTLVAGIIAAAPDAQSDNFSGVAPDVTLISIRQSS 164 RLP+VVAGGDYV TGDG +DCDAHGTLVAG+IA P A D+ GVAP+ T+ISIRQSS Sbjct 98 ARLPRVVAGGDYVGTGDGLSDCDAHGTLVAGVIAGQPSAD-DDVVGVAPESTIISIRQSS 156 Query 165 SKF-APVGDPSST----GVGDVDTMAKAVRTAADLGASVINISSIACVPAAAAPDDRALG 219 + A D +T G G + T+A+AV A DLGA VINIS +AC AA PDD LG Sbjct 157 GAYGAKRSDRDATVVGAGYGPIATLARAVVRAVDLGARVINISEVACTDAARPPDDGVLG 216 Query 220 AALAYAVDVKNAVIVAAAGNTGGAAQCPPQAP--GVTRD----SVTVAVSPAWYDDYVLT 273 +ALA+A D ++ V+VAAAGN C Q P + D V V+PA + VLT Sbjct 217 SALAFARD-RDVVVVAAAGNLTETTACREQNPSGAASTDRGWAQVRTLVTPARFAPLVLT 275 Query 274 VGSVNA-QGEPSAFTLAGPWVDVAATGEAVTSLS--PFGDGTVNRLGGQHGSIPISGTSY 330 VG+V A G P+ F+L GPWV VAA G V L+ P G V L G+ P++GTSY Sbjct 276 VGAVKAIDGTPADFSLRGPWVGVAAPGTDVVGLAPGPRGPRLVGGLNTVEGTAPLAGTSY 335 Query 331 AAPVVSGLAALIRARFPTLTARQVMQRIESTAHHPPAGWDPLVGNGTVDALAAVSSDSIP 390 AAP VSGLAALIR+R+P LTA QV+ RI +TAH G D VG+G VD +AA++ D P Sbjct 336 AAPYVSGLAALIRSRYPQLTATQVIDRIVTTAHG--GGHDSAVGSGVVDPVAALTDDDDP 393 Query 391 QAGTATSDPAPVAVPV 406 P P++ P+ Sbjct 394 S-------PEPISRPL 402 >gi|298523762|ref|ZP_07011171.1| membrane-anchored mycosin [Mycobacterium tuberculosis 94_M4241A] gi|298493556|gb|EFI28850.1| membrane-anchored mycosin [Mycobacterium tuberculosis 94_M4241A] Length=449 Score = 270 bits (689), Expect = 5e-70, Method: Compositional matrix adjust. Identities = 196/456 (43%), Positives = 257/456 (57%), Gaps = 37/456 (8%) Query 18 LSGLGTPVAHAVSPPPIDERWLPESALPAPPRPTVQREVCTEVTAESGRAFGRAERSAQL 77 ++G TP A A+ PP +D P S P P P QR C+ G G S + Sbjct 3 VAGWWTPPAWAIGPPVVDAAAQPPSGDPGPVAPMEQRGACSVSGVIPGTDPGVPTPSQTM 62 Query 78 ADLDQVWRLTRGAGQRVAVIDTGVARHRRLPKVVAGGDYVFTGDGTADCDAHGTLVAGII 137 +L W+ +RG GQ VA+IDTGV RLP V AGGD+V + DG DCD HGTLVAGI+ Sbjct 63 LNLPAAWQFSRGEGQLVAIIDTGVQPGPRLPNVDAGGDFVESTDGLTDCDGHGTLVAGIV 122 Query 138 AAAPDAQSDNFSGVAPDVTLISIRQSSSKFAPV---GDPS-STGVGDVDTMAKAVRTAAD 193 A P +D FSGVAP L+SIR S+KF+P GDP + DV +A A+ AAD Sbjct 123 AGQPG--NDGFSGVAPAARLLSIRAMSTKFSPRTSGGDPQLAQATLDVAVLAGAIVHAAD 180 Query 194 LGASVINISSIACVPAAAAPDDRALGAALAYAVDVKNAVIVAAAGNTGG----AAQC--- 246 LGA VIN+S+I C+PA D ALGAA+ YA K+AVIVAAAGNTG +A C Sbjct 181 LGAKVINVSTITCLPADRMVDQAALGAAIRYAAVDKDAVIVAAAGNTGASGSVSASCDSN 240 Query 247 ----------PPQAPGVTRDSVTVAVSPAWYDDYVLTVGSVNAQGEPSAFTLAGPWVDVA 296 P GVT S+ P+W+ YVL+V S+ + G+PS F++ GPWV +A Sbjct 241 PLTDLSRPDDPRNWAGVTSVSI-----PSWWQPYVLSVASLTSAGQPSKFSMPGPWVGIA 295 Query 297 ATGEAVTSLSPFGDGTV-NRLGGQHGS-IPISGTSYAAPVVSGLAALIRARFPTLTARQV 354 A GE + S+S GDG + N L H + +SGTSYAA VSG+AAL+R+R+P L A +V Sbjct 296 APGENIASVSNSGDGALANGLPDAHQKLVALSGTSYAAGYVSGVAALVRSRYPGLNATEV 355 Query 355 MQRIESTAHHPPAGWDPLVGNGTVDALAAVSSDSIPQAGTATSDPAPVAVPVPRRSTPGP 414 ++R+ +TAH +VG G +DA+AA++ +P + PA P + Sbjct 356 VRRLTATAHRGARESSNIVGAGNLDAVAALTWQ-LPAEPGGGAAPAKPVADPPVPAP--- 411 Query 415 SDRRALHTAFAGAAI--CLLALM-ATLATASRRLRP 447 D + AFAGAA L+ L AT+A A RR P Sbjct 412 KDTTPRNVAFAGAAALSVLVGLTAATVAIARRRREP 447 >gi|262201636|ref|YP_003272844.1| peptidase S8/S53 subtilisin kexin sedolisin [Gordonia bronchialis DSM 43247] gi|262084983|gb|ACY20951.1| peptidase S8 and S53 subtilisin kexin sedolisin [Gordonia bronchialis DSM 43247] Length=450 Score = 268 bits (685), Expect = 2e-69, Method: Compositional matrix adjust. Identities = 182/391 (47%), Positives = 230/391 (59%), Gaps = 27/391 (6%) Query 34 IDERWLPESALPAPPRPTVQREVCTEVTAESGRAFGRAERSAQLADLDQVWRLTRGAGQR 93 ID L SA APP PT Q CT TA S R++ + + + + D++WR RGAGQR Sbjct 22 IDTGALIRSAPVAPPEPTRQSHHCT--TATSIRSYAKPGAAQAMMNFDELWRFGRGAGQR 79 Query 94 VAVIDTGVARHRRLPKVVAGGDYVFTGDGTADCDAHGTLVAGIIAAAPDAQSDNFSGVAP 153 +AVIDTGV H RL +V+ GGDYV G G DCDAHGTLVAGIIAA P + SD F+G+AP Sbjct 80 IAVIDTGVTPHPRLGRVIPGGDYVSDGVGLDDCDAHGTLVAGIIAARP-SSSDAFAGIAP 138 Query 154 DVTLISIRQSSSKFAPVGDPSS-------TGVGDVDTMAKAVRTAADLGASVINISSIAC 206 + T+I+IRQSS + +G G V T+A A+ A DL A+VINIS +AC Sbjct 139 ESTIIAIRQSSGAYEAADRKRESRKPDVGSGFGTVRTLAHAIVRAVDLRATVINISQVAC 198 Query 207 VPAAAAPDDRALGAALAYAVDVKNAVIVAAAGNTGGAAQCPPQAPGVTRD-----SVTVA 261 P A +D ALGAA+ YA D V+VAA A P P D SV+ Sbjct 199 APDADKLNDPALGAAVRYAYDRNVVVVVAAGNVESNGACRPQNQPPAADDPSGWKSVSTI 258 Query 262 VSPAWYDDYVLTVGSVNAQ-GEPSAFTLAGPWVDVAATGEAVTSLSPFGDGTVNRLGGQH 320 SPAW+ YVL VGSV+A G P +L GPWV VAA G + SL G+ + + Q Sbjct 259 ASPAWFAPYVLAVGSVDASTGTPLPSSLNGPWVSVAAPGNEIISLD-SARGSSSLVSAQR 317 Query 321 ---GSIPISGTSYAAPVVSGLAALIRARFPTLTARQVMQRIESTAHHPPAGWDPLVGNGT 377 G IP++GTS+A P V+G AALIRAR+P L+AR+VM RI TAH P G D +G G Sbjct 318 TETGPIPLTGTSFATPYVAGTAALIRARYPQLSAREVMDRIIRTAHAPGTGHDQQIGYGV 377 Query 378 VDALAAVSSDSIPQAGTATSDP---APVAVP 405 +D +AA+++ PQ DP AP+A P Sbjct 378 IDPVAALTAVLPPQ----RRDPNASAPIAAP 404 >gi|254230665|ref|ZP_04923992.1| membrane-anchored mycosin mycP3 [Mycobacterium tuberculosis C] gi|124599724|gb|EAY58734.1| membrane-anchored mycosin mycP3 [Mycobacterium tuberculosis C] Length=416 Score = 268 bits (684), Expect = 2e-69, Method: Compositional matrix adjust. Identities = 177/397 (45%), Positives = 234/397 (59%), Gaps = 30/397 (7%) Query 12 VSALATLSGLGTPVAHAVSPPPIDERWLPESALPAPPRPTVQREVCTEVTAESGRAFGRA 71 ++A ++G TP A A+ PP +D P S P P P QR C+ G G Sbjct 9 LAATVVVAGWWTPPAWAIGPPVVDAAAQPPSGDPGPVAPMEQRGACSVSGVIPGTDPGVP 68 Query 72 ERSAQLADLDQVWRLTRGAGQRVAVIDTGVARHRRLPKVVAGGDYVFTGDGTADCDAHGT 131 S + +L W+ +RG GQ VA+IDTGV RLP V AGGD+V + DG DCD HGT Sbjct 69 TPSQTMLNLPAAWQFSRGEGQLVAIIDTGVQPGPRLPNVDAGGDFVESTDGLTDCDGHGT 128 Query 132 LVAGIIAAAPDAQSDNFSGVAPDVTLISIRQSSSKFAPV---GDPS-STGVGDVDTMAKA 187 LVAGI+A P +D FSGVAP L+SIR S+KF+P GDP + DV +A A Sbjct 129 LVAGIVAGQPG--NDGFSGVAPAARLLSIRAMSTKFSPRTSGGDPQLAQATLDVAVLAGA 186 Query 188 VRTAADLGASVINISSIACVPAAAAPDDRALGAALAYAVDVKNAVIVAAAGNTGG----A 243 + AADLGA VIN+S+I C+PA D ALGAA+ YA K+AVIVAAAGNTG + Sbjct 187 IVHAADLGAKVINVSTITCLPADRMVDQAALGAAIRYAAVDKDAVIVAAAGNTGASGSVS 246 Query 244 AQC-------------PPQAPGVTRDSVTVAVSPAWYDDYVLTVGSVNAQGEPSAFTLAG 290 A C P GVT S+ P+W+ YVL+V S+ + G+PS F++ G Sbjct 247 ASCDSNPLTDLSRPDDPRNWAGVTSVSI-----PSWWQPYVLSVASLTSAGQPSKFSMPG 301 Query 291 PWVDVAATGEAVTSLSPFGDGTV-NRLGGQHGS-IPISGTSYAAPVVSGLAALIRARFPT 348 PWV +AA GE + S+S GDG + N L H + +SGTSYAA VSG+AAL+R+R+P Sbjct 302 PWVGIAAPGENIASVSNSGDGALANGLPDAHQKLVALSGTSYAAGYVSGVAALVRSRYPG 361 Query 349 LTARQVMQRIESTAHHPPAGWDPLVGNGTVDALAAVS 385 L A +V++R+ +TAH +VG G +DA+AA++ Sbjct 362 LNATEVVRRLTATAHRGARESSNIVGAGNLDAVAALT 398 >gi|15826894|ref|NP_301157.1| protease [Mycobacterium leprae TN] gi|221229372|ref|YP_002502788.1| putative secreted protease [Mycobacterium leprae Br4923] gi|2370272|emb|CAA75193.1| hypothetical protease [Mycobacterium leprae] gi|13092441|emb|CAC29549.1| probable secreted protease [Mycobacterium leprae] gi|219932479|emb|CAR70134.1| probable secreted protease [Mycobacterium leprae Br4923] Length=446 Score = 267 bits (683), Expect = 2e-69, Method: Compositional matrix adjust. Identities = 180/407 (45%), Positives = 236/407 (58%), Gaps = 24/407 (5%) Query 24 PVAHAVSPPPIDERWLPESALPAPPRPTVQREVCTEVTAESGRAFGRAERSAQLADLDQV 83 P A A++PP ID +P + P +PT Q+ +C+ T +F S + + Sbjct 17 PPALAINPPSIDPGAVPPD-VTGPDQPTEQKVMCSAPTTLPDSSFHDPPWSNIYIGVSEA 75 Query 84 WRLTRGAGQRVAVIDTGVARHRRLPKVVAGGDYV-FTGDGTADCDAHGTLVAGIIAAAPD 142 + GAG VAVIDTGV R+P GGD+V G+G +DCDAHGTL A II P Sbjct 76 HKFATGAGVTVAVIDTGVEASPRVPAE-PGGDFVDQAGNGLSDCDAHGTLTASIIGGRP- 133 Query 143 AQSDNFSGVAPDVTLISIRQSSSKFAPVG------DPSST-GVGDVDTMAKAVRTAADLG 195 A +D F GVAPDV L+S+RQ+S F PVG DP++ G + ++A+AV AA+LG Sbjct 134 APTDGFIGVAPDVRLLSLRQTSEAFQPVGVQPNANDPNAIPAAGSIRSLARAVVHAANLG 193 Query 196 ASVINISSIACVPAAAAPDDRALGAALAYAVDVKNAVIVAAAGNTGGAAQCPPQAPGVTR 255 ASVINIS AC A D+ LGAA+ YAV+VK VI+ AAGNTGG P P V+ Sbjct 194 ASVINISETACYKANKPLDESTLGAAINYAVNVKGVVIIVAAGNTGGDCTQNPM-PDVSM 252 Query 256 -------DSVTVAVSPAWYDDYVLTVGSVNAQGEPSAFTLAGPWVDVAATGEAVTSLSPF 308 V +PAWY VLTVG + G PS F++ GPWV VAA E +T+L Sbjct 253 PNDPRGWSKVQTIATPAWYAPLVLTVGGIAQNGMPSQFSVHGPWVSVAAPTENITTLGYN 312 Query 309 GDGTVNRLGGQHGSIPISGTSYAAPVVSGLAALIRARFPTLTARQVMQRIESTAHHPPAG 368 G+ VN L G+ G + ++GTS+A VSGLAAL+R RFP LT Q++ RI +TA HP G Sbjct 313 GE-PVNALPGEEGPVALAGTSFATAYVSGLAALLRQRFPDLTPAQIINRIIATARHPGGG 371 Query 369 WDPLVGNGTVDALAAVSSDSIPQAGTAT----SDPAPVAVPVPRRST 411 D +VG G +DA+AA++ D P + + S P PV P P R+T Sbjct 372 VDDIVGAGVIDAVAALTWDITPGSASELFNVRSVPPPVITPGPDRNT 418 Lambda K H 0.316 0.130 0.384 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 949115517168 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40