BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv3455c Length=256 Score E Sequences producing significant alignments: (Bits) Value gi|15843050|ref|NP_338087.1| tRNA pseudouridine synthase A [Myco... 508 3e-142 gi|121639375|ref|YP_979599.1| tRNA pseudouridine synthase A [Myc... 507 5e-142 gi|308371354|ref|ZP_07424662.2| tRNA pseudouridine synthase A tr... 507 6e-142 gi|289449159|ref|ZP_06438903.1| tRNA pseudouridine synthase A tr... 506 1e-141 gi|118616627|ref|YP_904959.1| tRNA pseudouridine synthase A [Myc... 432 3e-119 gi|254819223|ref|ZP_05224224.1| tRNA pseudouridine synthase A [M... 427 1e-117 gi|296168687|ref|ZP_06850436.1| tRNA pseudouridine synthase A [M... 426 1e-117 gi|41410333|ref|NP_963169.1| tRNA pseudouridine synthase A [Myco... 425 4e-117 gi|118462566|ref|YP_883531.1| tRNA pseudouridine synthase A [Myc... 423 1e-116 gi|336460702|gb|EGO39592.1| pseudouridylate synthase [Mycobacter... 422 3e-116 gi|342861871|ref|ZP_08718516.1| tRNA pseudouridine synthase A [M... 421 5e-116 gi|240167785|ref|ZP_04746444.1| tRNA pseudouridine synthase A [M... 415 4e-114 gi|183981112|ref|YP_001849403.1| pseudouridine synthase a, TruA ... 401 4e-110 gi|108798087|ref|YP_638284.1| tRNA pseudouridine synthase A [Myc... 394 7e-108 gi|126433747|ref|YP_001069438.1| tRNA pseudouridine synthase A [... 394 7e-108 gi|161723265|ref|NP_302320.2| tRNA pseudouridine synthase A [Myc... 383 1e-104 gi|24212680|sp|Q9X796.2|TRUA_MYCLE RecName: Full=tRNA pseudourid... 380 8e-104 gi|145225544|ref|YP_001136222.1| tRNA pseudouridine synthase A [... 378 4e-103 gi|315445896|ref|YP_004078775.1| pseudouridylate synthase I [Myc... 375 2e-102 gi|120402449|ref|YP_952278.1| tRNA pseudouridine synthase A [Myc... 373 2e-101 gi|221230534|ref|YP_002503950.1| putative pseudouridylate syntha... 372 2e-101 gi|118473191|ref|YP_885908.1| tRNA pseudouridine synthase A [Myc... 368 5e-100 gi|333991918|ref|YP_004524532.1| pseudouridine synthase a TruA [... 355 3e-96 gi|169630847|ref|YP_001704496.1| tRNA pseudouridine synthase A [... 329 2e-88 gi|167967303|ref|ZP_02549580.1| tRNA pseudouridine synthase A [M... 310 1e-82 gi|325675475|ref|ZP_08155159.1| tRNA pseudouridine synthase A [R... 307 1e-81 gi|312140887|ref|YP_004008223.1| tRNA pseudouridine synthase a [... 306 2e-81 gi|111023127|ref|YP_706099.1| pseudouridylate synthase [Rhodococ... 298 5e-79 gi|226365626|ref|YP_002783409.1| tRNA pseudouridine synthase Tru... 296 2e-78 gi|229489482|ref|ZP_04383345.1| tRNA pseudouridine synthase A [R... 291 5e-77 gi|226305372|ref|YP_002765330.1| tRNA pseudouridine synthase Tru... 290 2e-76 gi|54022806|ref|YP_117048.1| tRNA pseudouridine synthase A [Noca... 283 2e-74 gi|262203538|ref|YP_003274746.1| tRNA pseudouridine synthase A [... 278 5e-73 gi|296394888|ref|YP_003659772.1| tRNA pseudouridine synthase A [... 278 6e-73 gi|317505831|ref|ZP_07963676.1| tRNA pseudouridine synthase [Seg... 273 2e-71 gi|296141060|ref|YP_003648303.1| tRNA pseudouridine synthase A [... 270 2e-70 gi|319950123|ref|ZP_08024062.1| tRNA pseudouridine synthase A [D... 269 3e-70 gi|326383234|ref|ZP_08204922.1| tRNA pseudouridine synthase A [G... 267 1e-69 gi|302330101|gb|ADL20295.1| tRNA pseudouridine synthase A [Coryn... 266 2e-69 gi|334696185|gb|AEG80982.1| tRNA pseudouridine synthase A [Coryn... 266 3e-69 gi|300857811|ref|YP_003782794.1| tRNA pseudouridine synthase A [... 266 3e-69 gi|324999254|ref|ZP_08120366.1| tRNA pseudouridine synthase a [P... 265 3e-69 gi|337290062|ref|YP_004629083.1| tRNA pseudouridine synthase A [... 264 1e-68 gi|258651414|ref|YP_003200570.1| tRNA pseudouridine synthase A [... 262 5e-68 gi|284992843|ref|YP_003411397.1| tRNA pseudouridine synthase A [... 256 2e-66 gi|25027130|ref|NP_737184.1| tRNA pseudouridine synthase A [Cory... 253 1e-65 gi|255324781|ref|ZP_05365895.1| tRNA pseudouridine synthase A [C... 253 2e-65 gi|259506738|ref|ZP_05749638.1| tRNA pseudouridine synthase A [C... 253 2e-65 gi|296119322|ref|ZP_06837890.1| tRNA pseudouridine synthase A [C... 252 3e-65 gi|260579203|ref|ZP_05847093.1| tRNA pseudouridine synthase A [C... 252 3e-65 >gi|15843050|ref|NP_338087.1| tRNA pseudouridine synthase A [Mycobacterium tuberculosis CDC1551] gi|148824665|ref|YP_001289419.1| tRNA pseudouridine synthase A [Mycobacterium tuberculosis F11] gi|161352460|ref|NP_217972.2| tRNA pseudouridine synthase A [Mycobacterium tuberculosis H37Rv] 25 more sequence titles Length=297 Score = 508 bits (1309), Expect = 3e-142, Method: Compositional matrix adjust. Identities = 256/256 (100%), Positives = 256/256 (100%), Gaps = 0/256 (0%) Query 1 VGQRTVAGDLDAALTTIFRTPVRLRAAGRTDAGVHASGQVAHVDVPADALPNAYPRAGHV 60 VGQRTVAGDLDAALTTIFRTPVRLRAAGRTDAGVHASGQVAHVDVPADALPNAYPRAGHV Sbjct 42 VGQRTVAGDLDAALTTIFRTPVRLRAAGRTDAGVHASGQVAHVDVPADALPNAYPRAGHV 101 Query 61 GDPEFLPLLRRLGRFLPADVRILDITRAPAGFDARFSALRRHYVYRLSTAPYGVEPQQAR 120 GDPEFLPLLRRLGRFLPADVRILDITRAPAGFDARFSALRRHYVYRLSTAPYGVEPQQAR Sbjct 102 GDPEFLPLLRRLGRFLPADVRILDITRAPAGFDARFSALRRHYVYRLSTAPYGVEPQQAR 161 Query 121 YITAWPRELDLDAMTAASRDLMGLHDFAAFCRHREGATTIRDLQRLDWSRAGTLVTAHVT 180 YITAWPRELDLDAMTAASRDLMGLHDFAAFCRHREGATTIRDLQRLDWSRAGTLVTAHVT Sbjct 162 YITAWPRELDLDAMTAASRDLMGLHDFAAFCRHREGATTIRDLQRLDWSRAGTLVTAHVT 221 Query 181 ADAFCWSMVRSLVGALLAVGEHRRATTWCRELLTATGRSSDFAVAPAHGLTLIQVDYPPD 240 ADAFCWSMVRSLVGALLAVGEHRRATTWCRELLTATGRSSDFAVAPAHGLTLIQVDYPPD Sbjct 222 ADAFCWSMVRSLVGALLAVGEHRRATTWCRELLTATGRSSDFAVAPAHGLTLIQVDYPPD 281 Query 241 DQLASRNLVTRDVRSG 256 DQLASRNLVTRDVRSG Sbjct 282 DQLASRNLVTRDVRSG 297 >gi|121639375|ref|YP_979599.1| tRNA pseudouridine synthase A [Mycobacterium bovis BCG str. Pasteur 1173P2] gi|148663320|ref|YP_001284843.1| tRNA pseudouridine synthase A [Mycobacterium tuberculosis H37Ra] gi|224991871|ref|YP_002646560.1| tRNA pseudouridine synthase A [Mycobacterium bovis BCG str. Tokyo 172] 37 more sequence titles Length=256 Score = 507 bits (1306), Expect = 5e-142, Method: Compositional matrix adjust. Identities = 255/256 (99%), Positives = 256/256 (100%), Gaps = 0/256 (0%) Query 1 VGQRTVAGDLDAALTTIFRTPVRLRAAGRTDAGVHASGQVAHVDVPADALPNAYPRAGHV 60 +GQRTVAGDLDAALTTIFRTPVRLRAAGRTDAGVHASGQVAHVDVPADALPNAYPRAGHV Sbjct 1 MGQRTVAGDLDAALTTIFRTPVRLRAAGRTDAGVHASGQVAHVDVPADALPNAYPRAGHV 60 Query 61 GDPEFLPLLRRLGRFLPADVRILDITRAPAGFDARFSALRRHYVYRLSTAPYGVEPQQAR 120 GDPEFLPLLRRLGRFLPADVRILDITRAPAGFDARFSALRRHYVYRLSTAPYGVEPQQAR Sbjct 61 GDPEFLPLLRRLGRFLPADVRILDITRAPAGFDARFSALRRHYVYRLSTAPYGVEPQQAR 120 Query 121 YITAWPRELDLDAMTAASRDLMGLHDFAAFCRHREGATTIRDLQRLDWSRAGTLVTAHVT 180 YITAWPRELDLDAMTAASRDLMGLHDFAAFCRHREGATTIRDLQRLDWSRAGTLVTAHVT Sbjct 121 YITAWPRELDLDAMTAASRDLMGLHDFAAFCRHREGATTIRDLQRLDWSRAGTLVTAHVT 180 Query 181 ADAFCWSMVRSLVGALLAVGEHRRATTWCRELLTATGRSSDFAVAPAHGLTLIQVDYPPD 240 ADAFCWSMVRSLVGALLAVGEHRRATTWCRELLTATGRSSDFAVAPAHGLTLIQVDYPPD Sbjct 181 ADAFCWSMVRSLVGALLAVGEHRRATTWCRELLTATGRSSDFAVAPAHGLTLIQVDYPPD 240 Query 241 DQLASRNLVTRDVRSG 256 DQLASRNLVTRDVRSG Sbjct 241 DQLASRNLVTRDVRSG 256 >gi|308371354|ref|ZP_07424662.2| tRNA pseudouridine synthase A truA [Mycobacterium tuberculosis SUMu003] gi|308372553|ref|ZP_07667408.1| tRNA pseudouridine synthase A truA [Mycobacterium tuberculosis SUMu004] gi|308373747|ref|ZP_07667643.1| tRNA pseudouridine synthase A truA [Mycobacterium tuberculosis SUMu005] 10 more sequence titles Length=303 Score = 507 bits (1306), Expect = 6e-142, Method: Compositional matrix adjust. Identities = 256/256 (100%), Positives = 256/256 (100%), Gaps = 0/256 (0%) Query 1 VGQRTVAGDLDAALTTIFRTPVRLRAAGRTDAGVHASGQVAHVDVPADALPNAYPRAGHV 60 VGQRTVAGDLDAALTTIFRTPVRLRAAGRTDAGVHASGQVAHVDVPADALPNAYPRAGHV Sbjct 48 VGQRTVAGDLDAALTTIFRTPVRLRAAGRTDAGVHASGQVAHVDVPADALPNAYPRAGHV 107 Query 61 GDPEFLPLLRRLGRFLPADVRILDITRAPAGFDARFSALRRHYVYRLSTAPYGVEPQQAR 120 GDPEFLPLLRRLGRFLPADVRILDITRAPAGFDARFSALRRHYVYRLSTAPYGVEPQQAR Sbjct 108 GDPEFLPLLRRLGRFLPADVRILDITRAPAGFDARFSALRRHYVYRLSTAPYGVEPQQAR 167 Query 121 YITAWPRELDLDAMTAASRDLMGLHDFAAFCRHREGATTIRDLQRLDWSRAGTLVTAHVT 180 YITAWPRELDLDAMTAASRDLMGLHDFAAFCRHREGATTIRDLQRLDWSRAGTLVTAHVT Sbjct 168 YITAWPRELDLDAMTAASRDLMGLHDFAAFCRHREGATTIRDLQRLDWSRAGTLVTAHVT 227 Query 181 ADAFCWSMVRSLVGALLAVGEHRRATTWCRELLTATGRSSDFAVAPAHGLTLIQVDYPPD 240 ADAFCWSMVRSLVGALLAVGEHRRATTWCRELLTATGRSSDFAVAPAHGLTLIQVDYPPD Sbjct 228 ADAFCWSMVRSLVGALLAVGEHRRATTWCRELLTATGRSSDFAVAPAHGLTLIQVDYPPD 287 Query 241 DQLASRNLVTRDVRSG 256 DQLASRNLVTRDVRSG Sbjct 288 DQLASRNLVTRDVRSG 303 >gi|289449159|ref|ZP_06438903.1| tRNA pseudouridine synthase A truA [Mycobacterium tuberculosis CPHL_A] gi|289422117|gb|EFD19318.1| tRNA pseudouridine synthase A truA [Mycobacterium tuberculosis CPHL_A] Length=256 Score = 506 bits (1304), Expect = 1e-141, Method: Compositional matrix adjust. Identities = 254/256 (99%), Positives = 256/256 (100%), Gaps = 0/256 (0%) Query 1 VGQRTVAGDLDAALTTIFRTPVRLRAAGRTDAGVHASGQVAHVDVPADALPNAYPRAGHV 60 +GQRTVAGDLDAALTTIFRTPVRLRAAGRTDAGVHASGQVAHVDVPADALPNAYPRAGHV Sbjct 1 MGQRTVAGDLDAALTTIFRTPVRLRAAGRTDAGVHASGQVAHVDVPADALPNAYPRAGHV 60 Query 61 GDPEFLPLLRRLGRFLPADVRILDITRAPAGFDARFSALRRHYVYRLSTAPYGVEPQQAR 120 GDPEFLPLLRRLGRFLPADVRILDITRAPAGFDARFSALRRHYVYRLSTAPYGVEPQQAR Sbjct 61 GDPEFLPLLRRLGRFLPADVRILDITRAPAGFDARFSALRRHYVYRLSTAPYGVEPQQAR 120 Query 121 YITAWPRELDLDAMTAASRDLMGLHDFAAFCRHREGATTIRDLQRLDWSRAGTLVTAHVT 180 YITAWPRELDLDAMTAASRDLMGLHDFAAFCRHREGATTIRDLQRLDWSRAG+LVTAHVT Sbjct 121 YITAWPRELDLDAMTAASRDLMGLHDFAAFCRHREGATTIRDLQRLDWSRAGSLVTAHVT 180 Query 181 ADAFCWSMVRSLVGALLAVGEHRRATTWCRELLTATGRSSDFAVAPAHGLTLIQVDYPPD 240 ADAFCWSMVRSLVGALLAVGEHRRATTWCRELLTATGRSSDFAVAPAHGLTLIQVDYPPD Sbjct 181 ADAFCWSMVRSLVGALLAVGEHRRATTWCRELLTATGRSSDFAVAPAHGLTLIQVDYPPD 240 Query 241 DQLASRNLVTRDVRSG 256 DQLASRNLVTRDVRSG Sbjct 241 DQLASRNLVTRDVRSG 256 >gi|118616627|ref|YP_904959.1| tRNA pseudouridine synthase A [Mycobacterium ulcerans Agy99] gi|118568737|gb|ABL03488.1| pseudouridine synthase a, TruA [Mycobacterium ulcerans Agy99] Length=260 Score = 432 bits (1110), Expect = 3e-119, Method: Compositional matrix adjust. Identities = 211/254 (84%), Positives = 227/254 (90%), Gaps = 0/254 (0%) Query 2 GQRTVAGDLDAALTTIFRTPVRLRAAGRTDAGVHASGQVAHVDVPADALPNAYPRAGHVG 61 GQRTVAG LD ALTT+ RTPVRLRAAGRTDAGVHA+GQVAH DVP DALPNAY R+ G Sbjct 4 GQRTVAGVLDEALTTVLRTPVRLRAAGRTDAGVHATGQVAHADVPVDALPNAYSRSARAG 63 Query 62 DPEFLPLLRRLGRFLPADVRILDITRAPAGFDARFSALRRHYVYRLSTAPYGVEPQQARY 121 DPEFLPL+RRL RFLPAD+R+LDI RAP FDARFSALRRHYVYRLSTAPYGVEPQQARY Sbjct 64 DPEFLPLVRRLARFLPADLRVLDIARAPTAFDARFSALRRHYVYRLSTAPYGVEPQQARY 123 Query 122 ITAWPRELDLDAMTAASRDLMGLHDFAAFCRHREGATTIRDLQRLDWSRAGTLVTAHVTA 181 +T WPRELD+DAMT AS++L+GLH+FAAFCR REGATTIRDLQRLDWSR G LVTA V+A Sbjct 124 VTVWPRELDIDAMTVASQELLGLHNFAAFCRRREGATTIRDLQRLDWSRNGHLVTAQVSA 183 Query 182 DAFCWSMVRSLVGALLAVGEHRRATTWCRELLTATGRSSDFAVAPAHGLTLIQVDYPPDD 241 DAFCWSMVRSLVGALLAVGEHRR WCRELLTAT RSSDFA APAHGL L +VDYPPDD Sbjct 184 DAFCWSMVRSLVGALLAVGEHRRTPDWCRELLTATARSSDFAAAPAHGLVLAKVDYPPDD 243 Query 242 QLASRNLVTRDVRS 255 QLASR L+TRD+RS Sbjct 244 QLASRVLITRDLRS 257 >gi|254819223|ref|ZP_05224224.1| tRNA pseudouridine synthase A [Mycobacterium intracellulare ATCC 13950] Length=251 Score = 427 bits (1097), Expect = 1e-117, Method: Compositional matrix adjust. Identities = 208/250 (84%), Positives = 229/250 (92%), Gaps = 0/250 (0%) Query 6 VAGDLDAALTTIFRTPVRLRAAGRTDAGVHASGQVAHVDVPADALPNAYPRAGHVGDPEF 65 +AG LD ALTTIFRTPVRLRAAGRTDAGVHA+GQVAHVDVPA ALPNAY RA HVG+ EF Sbjct 1 MAGVLDEALTTIFRTPVRLRAAGRTDAGVHATGQVAHVDVPAAALPNAYSRAPHVGEAEF 60 Query 66 LPLLRRLGRFLPADVRILDITRAPAGFDARFSALRRHYVYRLSTAPYGVEPQQARYITAW 125 LPLLRRLGRFLP DVR++DI RAPAGFDARFSALRRHYVYRLSTAP+GV+PQQ RY+TAW Sbjct 61 LPLLRRLGRFLPTDVRVVDIVRAPAGFDARFSALRRHYVYRLSTAPWGVDPQQVRYVTAW 120 Query 126 PRELDLDAMTAASRDLMGLHDFAAFCRHREGATTIRDLQRLDWSRAGTLVTAHVTADAFC 185 PR LD++AM ASRDL+GLHDFAAFCRHRE ATTIRDLQRL+W+R G L+TA V+ADAFC Sbjct 121 PRPLDVEAMATASRDLLGLHDFAAFCRHRENATTIRDLQRLEWTREGDLITARVSADAFC 180 Query 186 WSMVRSLVGALLAVGEHRRATTWCRELLTATGRSSDFAVAPAHGLTLIQVDYPPDDQLAS 245 WSMVRSLVGALLAVGEHRR +WCRELL+AT RSSD+A APAHGLTL+ VDYPPDDQLA+ Sbjct 181 WSMVRSLVGALLAVGEHRRPVSWCRELLSATARSSDYATAPAHGLTLVGVDYPPDDQLAA 240 Query 246 RNLVTRDVRS 255 RNL+TRDVRS Sbjct 241 RNLITRDVRS 250 >gi|296168687|ref|ZP_06850436.1| tRNA pseudouridine synthase A [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295896596|gb|EFG76237.1| tRNA pseudouridine synthase A [Mycobacterium parascrofulaceum ATCC BAA-614] Length=302 Score = 426 bits (1096), Expect = 1e-117, Method: Compositional matrix adjust. Identities = 210/254 (83%), Positives = 227/254 (90%), Gaps = 0/254 (0%) Query 2 GQRTVAGDLDAALTTIFRTPVRLRAAGRTDAGVHASGQVAHVDVPADALPNAYPRAGHVG 61 GQRTVAG LD ALTT+FR P+RLRAAGRTD GVHA+GQVAHVDVP DALPNAYPRA VG Sbjct 48 GQRTVAGVLDEALTTLFRAPMRLRAAGRTDTGVHATGQVAHVDVPPDALPNAYPRAPRVG 107 Query 62 DPEFLPLLRRLGRFLPADVRILDITRAPAGFDARFSALRRHYVYRLSTAPYGVEPQQARY 121 +PEFLPL+RRLGRFLP DVR+L I RAPAGFDARFSALRRHY YRLSTAPYGVEPQ+ARY Sbjct 108 EPEFLPLVRRLGRFLPTDVRVLGIARAPAGFDARFSALRRHYTYRLSTAPYGVEPQRARY 167 Query 122 ITAWPRELDLDAMTAASRDLMGLHDFAAFCRHREGATTIRDLQRLDWSRAGTLVTAHVTA 181 +TAWPR LD+DAM AASRDL+GLHDFA FCRHR ATTIRDLQ LDWSR G L+TAHVTA Sbjct 168 VTAWPRPLDVDAMAAASRDLVGLHDFAGFCRHRPNATTIRDLQGLDWSRDGELITAHVTA 227 Query 182 DAFCWSMVRSLVGALLAVGEHRRATTWCRELLTATGRSSDFAVAPAHGLTLIQVDYPPDD 241 DAFCWSMVRSLVGALLAVGEHRR +WCR LLTAT RSSDFA AP HGLTL+ VDYPPDD Sbjct 228 DAFCWSMVRSLVGALLAVGEHRRPVSWCRGLLTATSRSSDFAAAPPHGLTLVGVDYPPDD 287 Query 242 QLASRNLVTRDVRS 255 +L +RNLVTRD+R+ Sbjct 288 ELEARNLVTRDLRT 301 >gi|41410333|ref|NP_963169.1| tRNA pseudouridine synthase A [Mycobacterium avium subsp. paratuberculosis K-10] gi|51316707|sp|Q73S41.1|TRUA_MYCPA RecName: Full=tRNA pseudouridine synthase A; AltName: Full=tRNA pseudouridine(38-40) synthase; AltName: Full=tRNA pseudouridylate synthase I; AltName: Full=tRNA-uridine isomerase I gi|41399167|gb|AAS06785.1| TruA [Mycobacterium avium subsp. paratuberculosis K-10] Length=251 Score = 425 bits (1092), Expect = 4e-117, Method: Compositional matrix adjust. Identities = 208/250 (84%), Positives = 230/250 (92%), Gaps = 0/250 (0%) Query 6 VAGDLDAALTTIFRTPVRLRAAGRTDAGVHASGQVAHVDVPADALPNAYPRAGHVGDPEF 65 +AG LD ALTT+FRTPVRLRAAGRTDAGVHA+GQVAH+DVP ALPNAYPRA HVG+ EF Sbjct 1 MAGVLDEALTTVFRTPVRLRAAGRTDAGVHATGQVAHLDVPGTALPNAYPRAPHVGEAEF 60 Query 66 LPLLRRLGRFLPADVRILDITRAPAGFDARFSALRRHYVYRLSTAPYGVEPQQARYITAW 125 PLLRRLGRFLP DVR++DITRAPAGFDARFSALRRHYVYRLSTAP+GV PQQARY+TAW Sbjct 61 GPLLRRLGRFLPTDVRVVDITRAPAGFDARFSALRRHYVYRLSTAPWGVLPQQARYVTAW 120 Query 126 PRELDLDAMTAASRDLMGLHDFAAFCRHREGATTIRDLQRLDWSRAGTLVTAHVTADAFC 185 PR LD++AM AASRDL+GLHDFAAFCRHRE ATTIRDLQRLDW+R G L+TA V+ADAFC Sbjct 121 PRPLDVEAMAAASRDLLGLHDFAAFCRHRENATTIRDLQRLDWTRDGDLITARVSADAFC 180 Query 186 WSMVRSLVGALLAVGEHRRATTWCRELLTATGRSSDFAVAPAHGLTLIQVDYPPDDQLAS 245 WSMVRSLVGALLAVGE+RR +WCRELL+AT RSSD+A APAHGLTL+ VDYPPDDQLA+ Sbjct 181 WSMVRSLVGALLAVGENRRPVSWCRELLSATNRSSDYATAPAHGLTLVGVDYPPDDQLAA 240 Query 246 RNLVTRDVRS 255 RNL+TRDVRS Sbjct 241 RNLITRDVRS 250 >gi|118462566|ref|YP_883531.1| tRNA pseudouridine synthase A [Mycobacterium avium 104] gi|254776828|ref|ZP_05218344.1| tRNA pseudouridine synthase A [Mycobacterium avium subsp. avium ATCC 25291] gi|118163853|gb|ABK64750.1| tRNA pseudouridine synthase A [Mycobacterium avium 104] Length=251 Score = 423 bits (1088), Expect = 1e-116, Method: Compositional matrix adjust. Identities = 207/250 (83%), Positives = 229/250 (92%), Gaps = 0/250 (0%) Query 6 VAGDLDAALTTIFRTPVRLRAAGRTDAGVHASGQVAHVDVPADALPNAYPRAGHVGDPEF 65 +AG LD ALTT+FRTPVRLRAAGRTDAGVHA+GQVAH+DVP ALPNAYPRA HVG+ EF Sbjct 1 MAGVLDEALTTVFRTPVRLRAAGRTDAGVHATGQVAHLDVPGTALPNAYPRAPHVGEAEF 60 Query 66 LPLLRRLGRFLPADVRILDITRAPAGFDARFSALRRHYVYRLSTAPYGVEPQQARYITAW 125 PLLRRLGRFLP DVR++DITRAPAGFDARFSALRRHYVYRLSTAP+GV PQQARY+TAW Sbjct 61 GPLLRRLGRFLPTDVRVVDITRAPAGFDARFSALRRHYVYRLSTAPWGVLPQQARYVTAW 120 Query 126 PRELDLDAMTAASRDLMGLHDFAAFCRHREGATTIRDLQRLDWSRAGTLVTAHVTADAFC 185 PR LD++AM AASRDL+GLHDFAAFCRHRE ATTIRDLQRLDW+R G L+ A V+ADAFC Sbjct 121 PRPLDVEAMAAASRDLLGLHDFAAFCRHRENATTIRDLQRLDWTRDGDLIIARVSADAFC 180 Query 186 WSMVRSLVGALLAVGEHRRATTWCRELLTATGRSSDFAVAPAHGLTLIQVDYPPDDQLAS 245 WSMVRSLVGALLAVGE+RR +WCRELL+AT RSSD+A APAHGLTL+ VDYPPDDQLA+ Sbjct 181 WSMVRSLVGALLAVGENRRPVSWCRELLSATNRSSDYATAPAHGLTLVGVDYPPDDQLAA 240 Query 246 RNLVTRDVRS 255 RNL+TRDVRS Sbjct 241 RNLITRDVRS 250 >gi|336460702|gb|EGO39592.1| pseudouridylate synthase [Mycobacterium avium subsp. paratuberculosis S397] Length=248 Score = 422 bits (1085), Expect = 3e-116, Method: Compositional matrix adjust. Identities = 206/246 (84%), Positives = 227/246 (93%), Gaps = 0/246 (0%) Query 10 LDAALTTIFRTPVRLRAAGRTDAGVHASGQVAHVDVPADALPNAYPRAGHVGDPEFLPLL 69 LD ALTT+FRTPVRLRAAGRTDAGVHA+GQVAH+DVP ALPNAYPRA HVG+ EF PLL Sbjct 2 LDEALTTVFRTPVRLRAAGRTDAGVHATGQVAHLDVPGTALPNAYPRAPHVGEAEFGPLL 61 Query 70 RRLGRFLPADVRILDITRAPAGFDARFSALRRHYVYRLSTAPYGVEPQQARYITAWPREL 129 RRLGRFLP DVR++DITRAPAGFDARFSALRRHYVYRLSTAP+GV PQQARY+TAWPR L Sbjct 62 RRLGRFLPTDVRVVDITRAPAGFDARFSALRRHYVYRLSTAPWGVLPQQARYVTAWPRPL 121 Query 130 DLDAMTAASRDLMGLHDFAAFCRHREGATTIRDLQRLDWSRAGTLVTAHVTADAFCWSMV 189 D++AM AASRDL+GLHDFAAFCRHRE ATTIRDLQRLDW+R G L+TA V+ADAFCWSMV Sbjct 122 DVEAMAAASRDLLGLHDFAAFCRHRENATTIRDLQRLDWTRDGDLITARVSADAFCWSMV 181 Query 190 RSLVGALLAVGEHRRATTWCRELLTATGRSSDFAVAPAHGLTLIQVDYPPDDQLASRNLV 249 RSLVGALLAVGE+RR +WCRELL+AT RSSD+A APAHGLTL+ VDYPPDDQLA+RNL+ Sbjct 182 RSLVGALLAVGENRRPVSWCRELLSATNRSSDYATAPAHGLTLVGVDYPPDDQLAARNLI 241 Query 250 TRDVRS 255 TRDVRS Sbjct 242 TRDVRS 247 >gi|342861871|ref|ZP_08718516.1| tRNA pseudouridine synthase A [Mycobacterium colombiense CECT 3035] gi|342130688|gb|EGT83992.1| tRNA pseudouridine synthase A [Mycobacterium colombiense CECT 3035] Length=252 Score = 421 bits (1082), Expect = 5e-116, Method: Compositional matrix adjust. Identities = 204/250 (82%), Positives = 229/250 (92%), Gaps = 0/250 (0%) Query 6 VAGDLDAALTTIFRTPVRLRAAGRTDAGVHASGQVAHVDVPADALPNAYPRAGHVGDPEF 65 +AG LD ALTT+FRTPVRLRAAGRTDAGVHA+GQVAHVDVP +ALPNAYPRA VG+PEF Sbjct 1 MAGVLDEALTTVFRTPVRLRAAGRTDAGVHATGQVAHVDVPPEALPNAYPRAPRVGEPEF 60 Query 66 LPLLRRLGRFLPADVRILDITRAPAGFDARFSALRRHYVYRLSTAPYGVEPQQARYITAW 125 LPLLRRLGRFLP DVR++ I RAPAGFDARFSALRRHYVYRLSTAP+GV+P QARY+TAW Sbjct 61 LPLLRRLGRFLPTDVRVVGIARAPAGFDARFSALRRHYVYRLSTAPWGVQPLQARYVTAW 120 Query 126 PRELDLDAMTAASRDLMGLHDFAAFCRHREGATTIRDLQRLDWSRAGTLVTAHVTADAFC 185 PR LD++AM ASRDL+GLHDFAAFCRHRE ATTIRDLQRL+W+R G L+TA V+ADAFC Sbjct 121 PRPLDVEAMATASRDLLGLHDFAAFCRHRENATTIRDLQRLEWTRDGDLITAQVSADAFC 180 Query 186 WSMVRSLVGALLAVGEHRRATTWCRELLTATGRSSDFAVAPAHGLTLIQVDYPPDDQLAS 245 WSMVRSLVGALLAVGEHRR ++CRELL+AT RSSDFA APAHGL+L+ VDYPPDDQLA+ Sbjct 181 WSMVRSLVGALLAVGEHRRPVSYCRELLSATERSSDFAAAPAHGLSLVGVDYPPDDQLAA 240 Query 246 RNLVTRDVRS 255 RNL+TRD+RS Sbjct 241 RNLITRDIRS 250 >gi|240167785|ref|ZP_04746444.1| tRNA pseudouridine synthase A [Mycobacterium kansasii ATCC 12478] Length=248 Score = 415 bits (1066), Expect = 4e-114, Method: Compositional matrix adjust. Identities = 204/246 (83%), Positives = 223/246 (91%), Gaps = 0/246 (0%) Query 10 LDAALTTIFRTPVRLRAAGRTDAGVHASGQVAHVDVPADALPNAYPRAGHVGDPEFLPLL 69 LDAALTTIFRTP+RLRAAGRTDAGVHASGQVAH DVP DALPNAY + G PEF PL+ Sbjct 2 LDAALTTIFRTPIRLRAAGRTDAGVHASGQVAHADVPVDALPNAYSHSVRAGHPEFRPLV 61 Query 70 RRLGRFLPADVRILDITRAPAGFDARFSALRRHYVYRLSTAPYGVEPQQARYITAWPREL 129 RRL RFLP+DVR++DI RAP FDARFSAL RHYVYRLSTAPYGV PQ ARY+TAWPR+L Sbjct 62 RRLSRFLPSDVRVIDIVRAPRDFDARFSALCRHYVYRLSTAPYGVVPQLARYVTAWPRDL 121 Query 130 DLDAMTAASRDLMGLHDFAAFCRHREGATTIRDLQRLDWSRAGTLVTAHVTADAFCWSMV 189 D++AMT ASR+L+GLHDFAAFCRHR+GATTIRDLQRLDW+R G LVTAHVTADAFCWSMV Sbjct 122 DVEAMTIASRELLGLHDFAAFCRHRDGATTIRDLQRLDWARDGDLVTAHVTADAFCWSMV 181 Query 190 RSLVGALLAVGEHRRATTWCRELLTATGRSSDFAVAPAHGLTLIQVDYPPDDQLASRNLV 249 RSLVGA+LAVGEHRR+T WCRELLTATGRSSDFA APAHGLTL+QVDYPPDDQLA+R L Sbjct 182 RSLVGAVLAVGEHRRSTAWCRELLTATGRSSDFAAAPAHGLTLVQVDYPPDDQLAARALT 241 Query 250 TRDVRS 255 TRD+RS Sbjct 242 TRDLRS 247 >gi|183981112|ref|YP_001849403.1| pseudouridine synthase a, TruA [Mycobacterium marinum M] gi|183174438|gb|ACC39548.1| pseudouridine synthase a, TruA [Mycobacterium marinum M] Length=237 Score = 401 bits (1031), Expect = 4e-110, Method: Compositional matrix adjust. Identities = 195/234 (84%), Positives = 210/234 (90%), Gaps = 0/234 (0%) Query 22 VRLRAAGRTDAGVHASGQVAHVDVPADALPNAYPRAGHVGDPEFLPLLRRLGRFLPADVR 81 +RLRAAGRTDAGVHA+GQVAH DVP DALPNAY R+ GDPEFLPL+RRL RFLPAD+R Sbjct 1 MRLRAAGRTDAGVHATGQVAHADVPVDALPNAYSRSARAGDPEFLPLVRRLARFLPADLR 60 Query 82 ILDITRAPAGFDARFSALRRHYVYRLSTAPYGVEPQQARYITAWPRELDLDAMTAASRDL 141 +LDI RAP FDARFSALRRHYVYRLSTAPYGVEPQQARY+T WPRELD+DAMT ASR+L Sbjct 61 VLDIARAPTAFDARFSALRRHYVYRLSTAPYGVEPQQARYVTVWPRELDIDAMTVASREL 120 Query 142 MGLHDFAAFCRHREGATTIRDLQRLDWSRAGTLVTAHVTADAFCWSMVRSLVGALLAVGE 201 +GLH+FAAFCR REGATTIRDLQRLDWSR G LVTA V+ADAFCWSMVRSLVGALLAVGE Sbjct 121 LGLHNFAAFCRRREGATTIRDLQRLDWSRNGHLVTAQVSADAFCWSMVRSLVGALLAVGE 180 Query 202 HRRATTWCRELLTATGRSSDFAVAPAHGLTLIQVDYPPDDQLASRNLVTRDVRS 255 HRR WCRELLTAT RSSDFA APAHGL L +VDYPPDDQLASR L+TRD+RS Sbjct 181 HRRTPDWCRELLTATARSSDFAAAPAHGLVLAKVDYPPDDQLASRVLITRDLRS 234 >gi|108798087|ref|YP_638284.1| tRNA pseudouridine synthase A [Mycobacterium sp. MCS] gi|119867183|ref|YP_937135.1| tRNA pseudouridine synthase A [Mycobacterium sp. KMS] gi|108768506|gb|ABG07228.1| tRNA pseudouridine synthase A [Mycobacterium sp. MCS] gi|119693272|gb|ABL90345.1| tRNA pseudouridine synthase A [Mycobacterium sp. KMS] Length=299 Score = 394 bits (1012), Expect = 7e-108, Method: Compositional matrix adjust. Identities = 194/253 (77%), Positives = 218/253 (87%), Gaps = 0/253 (0%) Query 2 GQRTVAGDLDAALTTIFRTPVRLRAAGRTDAGVHASGQVAHVDVPADALPNAYPRAGHVG 61 GQRTVAG +D ALTT+FRTPV +RAAGRTDAGVHA+GQVAHVDVP DALP+AYPR+ Sbjct 44 GQRTVAGLIDEALTTVFRTPVTVRAAGRTDAGVHATGQVAHVDVPDDALPHAYPRSARPD 103 Query 62 DPEFLPLLRRLGRFLPADVRILDITRAPAGFDARFSALRRHYVYRLSTAPYGVEPQQARY 121 +PEFLPL+RRLGRFLPADVRI DI RAP GFDARFSALRRHY YRL TAPYGVEPQ AR+ Sbjct 104 EPEFLPLVRRLGRFLPADVRIRDIIRAPTGFDARFSALRRHYTYRLGTAPYGVEPQSARF 163 Query 122 ITAWPRELDLDAMTAASRDLMGLHDFAAFCRHREGATTIRDLQRLDWSRAGTLVTAHVTA 181 +T WPR LD++AM A L+GL DFAAFCRHREGATTIRDLQRL+W+R G LVTA+V+A Sbjct 164 VTPWPRPLDVEAMNDAGSQLVGLRDFAAFCRHREGATTIRDLQRLEWTRDGDLVTAYVSA 223 Query 182 DAFCWSMVRSLVGALLAVGEHRRATTWCRELLTATGRSSDFAVAPAHGLTLIQVDYPPDD 241 DAFCWSMVRSLVGAL+AVGEHRR WC LL+AT RSS+FA AP GLTL+ VDYPPDD Sbjct 224 DAFCWSMVRSLVGALIAVGEHRREPEWCAGLLSATRRSSEFAAAPPQGLTLVGVDYPPDD 283 Query 242 QLASRNLVTRDVR 254 +LA+R LVTRD+R Sbjct 284 ELAARTLVTRDLR 296 >gi|126433747|ref|YP_001069438.1| tRNA pseudouridine synthase A [Mycobacterium sp. JLS] gi|126233547|gb|ABN96947.1| tRNA pseudouridine synthase A [Mycobacterium sp. JLS] Length=299 Score = 394 bits (1012), Expect = 7e-108, Method: Compositional matrix adjust. Identities = 194/253 (77%), Positives = 218/253 (87%), Gaps = 0/253 (0%) Query 2 GQRTVAGDLDAALTTIFRTPVRLRAAGRTDAGVHASGQVAHVDVPADALPNAYPRAGHVG 61 GQRTVAG +D ALTT+FRTPV +RAAGRTDAGVHA+GQVAHVDVP DALP+AYPR+ Sbjct 44 GQRTVAGLIDEALTTVFRTPVTVRAAGRTDAGVHATGQVAHVDVPDDALPHAYPRSARPD 103 Query 62 DPEFLPLLRRLGRFLPADVRILDITRAPAGFDARFSALRRHYVYRLSTAPYGVEPQQARY 121 +PEFLPL+RRLGRFLPADVRI DI RAP GFDARFSALRRHY YRL TAPYGVEPQ AR+ Sbjct 104 EPEFLPLVRRLGRFLPADVRIRDIIRAPTGFDARFSALRRHYTYRLGTAPYGVEPQSARF 163 Query 122 ITAWPRELDLDAMTAASRDLMGLHDFAAFCRHREGATTIRDLQRLDWSRAGTLVTAHVTA 181 +T WPR LD++AM A L+GL DFAAFCRHREGATTIRDLQRL+W+R G LVTA+V+A Sbjct 164 VTPWPRPLDVEAMNDAGSQLVGLRDFAAFCRHREGATTIRDLQRLEWTRDGDLVTAYVSA 223 Query 182 DAFCWSMVRSLVGALLAVGEHRRATTWCRELLTATGRSSDFAVAPAHGLTLIQVDYPPDD 241 DAFCWSMVRSLVGAL+AVGEHRR WC LL+AT RSS+FA AP GLTL+ VDYPPDD Sbjct 224 DAFCWSMVRSLVGALIAVGEHRREPEWCAGLLSATRRSSEFAAAPPQGLTLVGVDYPPDD 283 Query 242 QLASRNLVTRDVR 254 +LA+R LVTRD+R Sbjct 284 ELAARTLVTRDLR 296 >gi|161723265|ref|NP_302320.2| tRNA pseudouridine synthase A [Mycobacterium leprae TN] Length=320 Score = 383 bits (984), Expect = 1e-104, Method: Compositional matrix adjust. Identities = 197/254 (78%), Positives = 218/254 (86%), Gaps = 0/254 (0%) Query 2 GQRTVAGDLDAALTTIFRTPVRLRAAGRTDAGVHASGQVAHVDVPADALPNAYPRAGHVG 61 GQRTVAG LD A TT+FRTPVRLRAAGRTD GVHA+GQVAHVD+P AL A PR+ H G Sbjct 65 GQRTVAGVLDEAFTTVFRTPVRLRAAGRTDTGVHATGQVAHVDIPGTALSKANPRSPHTG 124 Query 62 DPEFLPLLRRLGRFLPADVRILDITRAPAGFDARFSALRRHYVYRLSTAPYGVEPQQARY 121 DPEFLPLLRRL R LP DVR+LDI AP GFDARFSALRRHY YRLSTAPYGV+P QARY Sbjct 125 DPEFLPLLRRLSRLLPVDVRVLDIACAPVGFDARFSALRRHYRYRLSTAPYGVQPNQARY 184 Query 122 ITAWPRELDLDAMTAASRDLMGLHDFAAFCRHREGATTIRDLQRLDWSRAGTLVTAHVTA 181 +TAWPRELDLD+M+AASRDL+GL DFA FCRHR GATTIR+LQRL+WSR G L+TAH+TA Sbjct 185 VTAWPRELDLDSMSAASRDLLGLRDFAVFCRHRHGATTIRELQRLEWSREGYLITAHITA 244 Query 182 DAFCWSMVRSLVGALLAVGEHRRATTWCRELLTATGRSSDFAVAPAHGLTLIQVDYPPDD 241 DAFCWSMVRSL+GALLAVG+HRR WC ELLT RSSDF APAHGLT I+VDYPPDD Sbjct 245 DAFCWSMVRSLIGALLAVGDHRRTIGWCGELLTKASRSSDFTTAPAHGLTFIRVDYPPDD 304 Query 242 QLASRNLVTRDVRS 255 +LA R ++TRD+RS Sbjct 305 ELAERAVITRDLRS 318 >gi|24212680|sp|Q9X796.2|TRUA_MYCLE RecName: Full=tRNA pseudouridine synthase A; AltName: Full=tRNA pseudouridine(38-40) synthase; AltName: Full=tRNA pseudouridylate synthase I; AltName: Full=tRNA-uridine isomerase I Length=286 Score = 380 bits (977), Expect = 8e-104, Method: Compositional matrix adjust. Identities = 197/254 (78%), Positives = 218/254 (86%), Gaps = 1/254 (0%) Query 2 GQRTVAGDLDAALTTIFRTPVRLRAAGRTDAGVHASGQVAHVDVPADALPNAYPRAGHVG 61 GQRTVAG LD A TT+FRTPVRLRAAGRTD GVHA+GQVAHVD+P AL A PR+ H G Sbjct 32 GQRTVAG-LDEAFTTVFRTPVRLRAAGRTDTGVHATGQVAHVDIPGTALSKANPRSPHTG 90 Query 62 DPEFLPLLRRLGRFLPADVRILDITRAPAGFDARFSALRRHYVYRLSTAPYGVEPQQARY 121 DPEFLPLLRRL R LP DVR+LDI AP GFDARFSALRRHY YRLSTAPYGV+P QARY Sbjct 91 DPEFLPLLRRLSRLLPVDVRVLDIACAPVGFDARFSALRRHYRYRLSTAPYGVQPNQARY 150 Query 122 ITAWPRELDLDAMTAASRDLMGLHDFAAFCRHREGATTIRDLQRLDWSRAGTLVTAHVTA 181 +TAWPRELDLD+M+AASRDL+GL DFA FCRHR GATTIR+LQRL+WSR G L+TAH+TA Sbjct 151 VTAWPRELDLDSMSAASRDLLGLRDFAVFCRHRHGATTIRELQRLEWSREGYLITAHITA 210 Query 182 DAFCWSMVRSLVGALLAVGEHRRATTWCRELLTATGRSSDFAVAPAHGLTLIQVDYPPDD 241 DAFCWSMVRSL+GALLAVG+HRR WC ELLT RSSDF APAHGLT I+VDYPPDD Sbjct 211 DAFCWSMVRSLIGALLAVGDHRRTIGWCGELLTKASRSSDFTTAPAHGLTFIRVDYPPDD 270 Query 242 QLASRNLVTRDVRS 255 +LA R ++TRD+RS Sbjct 271 ELAERAVITRDLRS 284 >gi|145225544|ref|YP_001136222.1| tRNA pseudouridine synthase A [Mycobacterium gilvum PYR-GCK] gi|145218030|gb|ABP47434.1| tRNA pseudouridine synthase A [Mycobacterium gilvum PYR-GCK] Length=298 Score = 378 bits (971), Expect = 4e-103, Method: Compositional matrix adjust. Identities = 185/254 (73%), Positives = 216/254 (86%), Gaps = 0/254 (0%) Query 2 GQRTVAGDLDAALTTIFRTPVRLRAAGRTDAGVHASGQVAHVDVPADALPNAYPRAGHVG 61 GQRTVAG +D AL+T+FRTPV RAAGRTD+GVHA+GQVAH D+P DALP+AYPR G Sbjct 41 GQRTVAGVIDDALSTVFRTPVLTRAAGRTDSGVHATGQVAHADIPTDALPHAYPRTVRAG 100 Query 62 DPEFLPLLRRLGRFLPADVRILDITRAPAGFDARFSALRRHYVYRLSTAPYGVEPQQARY 121 +PEF PL+RRLGR L DVR+ I RA GFDARFSALRRHYVYRL+TAPYGVEP +AR+ Sbjct 101 EPEFGPLVRRLGRMLTEDVRVRGIVRAAPGFDARFSALRRHYVYRLTTAPYGVEPAEARF 160 Query 122 ITAWPRELDLDAMTAASRDLMGLHDFAAFCRHREGATTIRDLQRLDWSRAGTLVTAHVTA 181 +TAWPR LD+DAM A+++++GLHDFAAFCRHR+GATTIR+LQRLD R G ++ HV+A Sbjct 161 VTAWPRPLDVDAMAGAAQNVLGLHDFAAFCRHRDGATTIRELQRLDCVRDGDRISVHVSA 220 Query 182 DAFCWSMVRSLVGALLAVGEHRRATTWCRELLTATGRSSDFAVAPAHGLTLIQVDYPPDD 241 DAFCW+MVRSLVGALLAVGEHRR TWC +LL A RSSDFA APA GLTL+ VDYPPDD Sbjct 221 DAFCWNMVRSLVGALLAVGEHRRDDTWCVQLLHARHRSSDFAAAPARGLTLVGVDYPPDD 280 Query 242 QLASRNLVTRDVRS 255 +LA+RNLVTRDVR+ Sbjct 281 ELAARNLVTRDVRT 294 >gi|315445896|ref|YP_004078775.1| pseudouridylate synthase I [Mycobacterium sp. Spyr1] gi|315264199|gb|ADU00941.1| pseudouridylate synthase I [Mycobacterium sp. Spyr1] Length=291 Score = 375 bits (964), Expect = 2e-102, Method: Compositional matrix adjust. Identities = 184/254 (73%), Positives = 216/254 (86%), Gaps = 0/254 (0%) Query 2 GQRTVAGDLDAALTTIFRTPVRLRAAGRTDAGVHASGQVAHVDVPADALPNAYPRAGHVG 61 GQRTVAG +D AL+T+FRTP+ RAAGRTD+GVHA+GQVAHVD+P DALP+AYPR G Sbjct 34 GQRTVAGVIDDALSTVFRTPMLTRAAGRTDSGVHATGQVAHVDIPTDALPHAYPRTVRAG 93 Query 62 DPEFLPLLRRLGRFLPADVRILDITRAPAGFDARFSALRRHYVYRLSTAPYGVEPQQARY 121 + EF PL+RRLGR L DVR+ I RA GFDARFSALRRHYVYRL+TAPYGVEP +AR+ Sbjct 94 EAEFGPLVRRLGRMLTEDVRVRGIVRAAPGFDARFSALRRHYVYRLTTAPYGVEPSEARF 153 Query 122 ITAWPRELDLDAMTAASRDLMGLHDFAAFCRHREGATTIRDLQRLDWSRAGTLVTAHVTA 181 +TAWPR LD+DAM A+++++GLHDFAAFCRHR+GATTIR+LQRLD R G ++ HV+A Sbjct 154 VTAWPRPLDVDAMAGAAQNVLGLHDFAAFCRHRDGATTIRELQRLDCVRDGDRISVHVSA 213 Query 182 DAFCWSMVRSLVGALLAVGEHRRATTWCRELLTATGRSSDFAVAPAHGLTLIQVDYPPDD 241 DAFCW+MVRSLVGALLAVGEHRR TWC +LL A RSSDFA APA GLTL+ VDYPPDD Sbjct 214 DAFCWNMVRSLVGALLAVGEHRRDDTWCVQLLHARHRSSDFAAAPARGLTLVGVDYPPDD 273 Query 242 QLASRNLVTRDVRS 255 +LA+RNLVTRDVR+ Sbjct 274 ELAARNLVTRDVRT 287 >gi|120402449|ref|YP_952278.1| tRNA pseudouridine synthase A [Mycobacterium vanbaalenii PYR-1] gi|119955267|gb|ABM12272.1| tRNA pseudouridine synthase A [Mycobacterium vanbaalenii PYR-1] Length=299 Score = 373 bits (957), Expect = 2e-101, Method: Compositional matrix adjust. Identities = 190/254 (75%), Positives = 215/254 (85%), Gaps = 0/254 (0%) Query 2 GQRTVAGDLDAALTTIFRTPVRLRAAGRTDAGVHASGQVAHVDVPADALPNAYPRAGHVG 61 GQRTVAG +D AL+T+FRTPV RAAGRTD+GVHA+GQVAHVDVPADALP AYPR G Sbjct 42 GQRTVAGAIDDALSTVFRTPVVTRAAGRTDSGVHATGQVAHVDVPADALPYAYPRTTRPG 101 Query 62 DPEFLPLLRRLGRFLPADVRILDITRAPAGFDARFSALRRHYVYRLSTAPYGVEPQQARY 121 + EF PL+RRLGR LP DVR+ +ITRA GFDARFSALRRHY+YRLSTAPYGVEP +AR+ Sbjct 102 EAEFGPLVRRLGRMLPEDVRVREITRAAPGFDARFSALRRHYLYRLSTAPYGVEPAEARF 161 Query 122 ITAWPRELDLDAMTAASRDLMGLHDFAAFCRHREGATTIRDLQRLDWSRAGTLVTAHVTA 181 +T WPR LD+ AM AA+R+L+GLHDFAAFCRHR+GATTIR+LQRLD R G V HV+A Sbjct 162 VTPWPRPLDVAAMAAAARELVGLHDFAAFCRHRDGATTIRELQRLDCVRDGDRVEVHVSA 221 Query 182 DAFCWSMVRSLVGALLAVGEHRRATTWCRELLTATGRSSDFAVAPAHGLTLIQVDYPPDD 241 DAFCW+MVRSLVGALLAVGEHRR WC LL ATGRSSDFA APA GLTL+ VDYPPD Sbjct 222 DAFCWNMVRSLVGALLAVGEHRRDAAWCAALLDATGRSSDFAAAPARGLTLVGVDYPPDA 281 Query 242 QLASRNLVTRDVRS 255 QL +RNLVTRD+R+ Sbjct 282 QLEARNLVTRDLRT 295 >gi|221230534|ref|YP_002503950.1| putative pseudouridylate synthase [Mycobacterium leprae Br4923] gi|4539110|emb|CAB39831.1| putative tRNA pseudouridine synthase A [Mycobacterium leprae] gi|13093610|emb|CAC30910.1| probable pseudouridylate synthase [Mycobacterium leprae] gi|219933641|emb|CAR72052.1| probable pseudouridylate synthase [Mycobacterium leprae Br4923] Length=249 Score = 372 bits (956), Expect = 2e-101, Method: Compositional matrix adjust. Identities = 190/247 (77%), Positives = 211/247 (86%), Gaps = 0/247 (0%) Query 10 LDAALTTIFRTPVRLRAAGRTDAGVHASGQVAHVDVPADALPNAYPRAGHVGDPEFLPLL 69 LD A TT+FRTPVRLRAAGRTD GVHA+GQVAHVD+P AL A PR+ H GDPEFLPLL Sbjct 2 LDEAFTTVFRTPVRLRAAGRTDTGVHATGQVAHVDIPGTALSKANPRSPHTGDPEFLPLL 61 Query 70 RRLGRFLPADVRILDITRAPAGFDARFSALRRHYVYRLSTAPYGVEPQQARYITAWPREL 129 RRL R LP DVR+LDI AP GFDARFSALRRHY YRLSTAPYGV+P QARY+TAWPREL Sbjct 62 RRLSRLLPVDVRVLDIACAPVGFDARFSALRRHYRYRLSTAPYGVQPNQARYVTAWPREL 121 Query 130 DLDAMTAASRDLMGLHDFAAFCRHREGATTIRDLQRLDWSRAGTLVTAHVTADAFCWSMV 189 DLD+M+AASRDL+GL DFA FCRHR GATTIR+LQRL+WSR G L+TAH+TADAFCWSMV Sbjct 122 DLDSMSAASRDLLGLRDFAVFCRHRHGATTIRELQRLEWSREGYLITAHITADAFCWSMV 181 Query 190 RSLVGALLAVGEHRRATTWCRELLTATGRSSDFAVAPAHGLTLIQVDYPPDDQLASRNLV 249 RSL+GALLAVG+HRR WC ELLT RSSDF APAHGLT I+VDYPPDD+LA R ++ Sbjct 182 RSLIGALLAVGDHRRTIGWCGELLTKASRSSDFTTAPAHGLTFIRVDYPPDDELAERAVI 241 Query 250 TRDVRSG 256 TRD+RS Sbjct 242 TRDLRSS 248 >gi|118473191|ref|YP_885908.1| tRNA pseudouridine synthase A [Mycobacterium smegmatis str. MC2 155] gi|118174478|gb|ABK75374.1| tRNA pseudouridine synthase A [Mycobacterium smegmatis str. MC2 155] Length=291 Score = 368 bits (944), Expect = 5e-100, Method: Compositional matrix adjust. Identities = 182/254 (72%), Positives = 210/254 (83%), Gaps = 0/254 (0%) Query 2 GQRTVAGDLDAALTTIFRTPVRLRAAGRTDAGVHASGQVAHVDVPADALPNAYPRAGHVG 61 GQRTVAG +D ALTT+FRTPV R AGRTD GVHA+GQVAHVDVPA+ALP+AYPR Sbjct 32 GQRTVAGVIDEALTTVFRTPVVTRVAGRTDTGVHATGQVAHVDVPAEALPHAYPRHTRPT 91 Query 62 DPEFLPLLRRLGRFLPADVRILDITRAPAGFDARFSALRRHYVYRLSTAPYGVEPQQARY 121 D EF PL+RRL FLPADVR+ DI RAPAGFDARFSALRRHYVYRL+TAPYG EP + R+ Sbjct 92 DAEFTPLVRRLAGFLPADVRVRDIVRAPAGFDARFSALRRHYVYRLTTAPYGPEPHETRF 151 Query 122 ITAWPRELDLDAMTAASRDLMGLHDFAAFCRHREGATTIRDLQRLDWSRAGTLVTAHVTA 181 +T W R LD+DAM AA+++L+GL+DFAAFCR+R GATTIRDLQRL+W R G + A+VTA Sbjct 152 VTPWTRPLDVDAMNAAAQELLGLNDFAAFCRYRAGATTIRDLQRLEWVRNGFYINAYVTA 211 Query 182 DAFCWSMVRSLVGALLAVGEHRRATTWCRELLTATGRSSDFAVAPAHGLTLIQVDYPPDD 241 DAFCW+MVRSLVGALL VGE RR+ W ELL AT RSS+F APA GLTL VDYPPDD Sbjct 212 DAFCWNMVRSLVGALLKVGEGRRSPEWTAELLGATSRSSEFPAAPARGLTLAAVDYPPDD 271 Query 242 QLASRNLVTRDVRS 255 +L +RN+VTRDVR+ Sbjct 272 ELEARNVVTRDVRT 285 >gi|333991918|ref|YP_004524532.1| pseudouridine synthase a TruA [Mycobacterium sp. JDM601] gi|333487886|gb|AEF37278.1| pseudouridine synthase a TruA [Mycobacterium sp. JDM601] Length=240 Score = 355 bits (911), Expect = 3e-96, Method: Compositional matrix adjust. Identities = 178/239 (75%), Positives = 198/239 (83%), Gaps = 0/239 (0%) Query 17 IFRTPVRLRAAGRTDAGVHASGQVAHVDVPADALPNAYPRAGHVGDPEFLPLLRRLGRFL 76 +FRTPVRL AAGRTD GVHA+GQVAHVDVP AL AY RA G+PEFL L RRL RFL Sbjct 1 MFRTPVRLFAAGRTDTGVHATGQVAHVDVPESALRYAYSRARRDGEPEFLALTRRLARFL 60 Query 77 PADVRILDITRAPAGFDARFSALRRHYVYRLSTAPYGVEPQQARYITAWPRELDLDAMTA 136 PADVR L + RA GFDARFSALRRHYVYRLSTA YGV PQ ARY+TAWPR LD++AM+ Sbjct 61 PADVRALRVERAAPGFDARFSALRRHYVYRLSTARYGVMPQSARYVTAWPRPLDVEAMSE 120 Query 137 ASRDLMGLHDFAAFCRHREGATTIRDLQRLDWSRAGTLVTAHVTADAFCWSMVRSLVGAL 196 AS+ L+GL+DFAAFCRHREGATTIRDLQRLDW R G LVTAHV+ADAFCWSMVRSLVGA+ Sbjct 121 ASQQLLGLNDFAAFCRHREGATTIRDLQRLDWVRDGDLVTAHVSADAFCWSMVRSLVGAV 180 Query 197 LAVGEHRRATTWCRELLTATGRSSDFAVAPAHGLTLIQVDYPPDDQLASRNLVTRDVRS 255 LAVGEHRR WC LL A+ RSSDF APA GLTL+ VDYPPDDQL +R +TR++R+ Sbjct 181 LAVGEHRRDAAWCAGLLNASRRSSDFTAAPARGLTLVGVDYPPDDQLGARTAITRELRT 239 >gi|169630847|ref|YP_001704496.1| tRNA pseudouridine synthase A [Mycobacterium abscessus ATCC 19977] gi|169242814|emb|CAM63842.1| tRNA pseudouridine synthase A [Mycobacterium abscessus] Length=294 Score = 329 bits (844), Expect = 2e-88, Method: Compositional matrix adjust. Identities = 171/254 (68%), Positives = 194/254 (77%), Gaps = 0/254 (0%) Query 1 VGQRTVAGDLDAALTTIFRTPVRLRAAGRTDAGVHASGQVAHVDVPADALPNAYPRAGHV 60 V QRTVAG L A TTI V+L AAGRTDAGVHA+GQVAH+DVP LP R Sbjct 36 VNQRTVAGVLGEAFTTIVGDSVQLYAAGRTDAGVHATGQVAHLDVPVACLPGLRGRYRPA 95 Query 61 GDPEFLPLLRRLGRFLPADVRILDITRAPAGFDARFSALRRHYVYRLSTAPYGVEPQQAR 120 G PEF L+RRL RFLP+DVR+LDI+RAPA FDARFSALRRHY YRLSTA +GV P Sbjct 96 GAPEFDRLVRRLSRFLPSDVRVLDISRAPAHFDARFSALRRHYEYRLSTASFGVLPLARH 155 Query 121 YITAWPRELDLDAMTAASRDLMGLHDFAAFCRHREGATTIRDLQRLDWSRAGTLVTAHVT 180 + W R LD+DAM ASR+L+GL DFAAFCRHREGATTIR+LQR DW G +TA+V+ Sbjct 156 DVVGWHRPLDVDAMNEASRNLLGLRDFAAFCRHREGATTIRELQRFDWGVDGQRLTAYVS 215 Query 181 ADAFCWSMVRSLVGALLAVGEHRRATTWCRELLTATGRSSDFAVAPAHGLTLIQVDYPPD 240 ADAFCWSMVRSLVGA+LAVGE RR WC +LL RSSDFA APA GLTL+ VDYPPD Sbjct 216 ADAFCWSMVRSLVGAVLAVGEGRRPVQWCVDLLNKERRSSDFAAAPARGLTLVGVDYPPD 275 Query 241 DQLASRNLVTRDVR 254 DQ+A+R ++TRDVR Sbjct 276 DQMAARVMITRDVR 289 >gi|167967303|ref|ZP_02549580.1| tRNA pseudouridine synthase A [Mycobacterium tuberculosis H37Ra] Length=243 Score = 310 bits (794), Expect = 1e-82, Method: Compositional matrix adjust. Identities = 152/153 (99%), Positives = 153/153 (100%), Gaps = 0/153 (0%) Query 104 VYRLSTAPYGVEPQQARYITAWPRELDLDAMTAASRDLMGLHDFAAFCRHREGATTIRDL 163 +YRLSTAPYGVEPQQARYITAWPRELDLDAMTAASRDLMGLHDFAAFCRHREGATTIRDL Sbjct 1 MYRLSTAPYGVEPQQARYITAWPRELDLDAMTAASRDLMGLHDFAAFCRHREGATTIRDL 60 Query 164 QRLDWSRAGTLVTAHVTADAFCWSMVRSLVGALLAVGEHRRATTWCRELLTATGRSSDFA 223 QRLDWSRAGTLVTAHVTADAFCWSMVRSLVGALLAVGEHRRATTWCRELLTATGRSSDFA Sbjct 61 QRLDWSRAGTLVTAHVTADAFCWSMVRSLVGALLAVGEHRRATTWCRELLTATGRSSDFA 120 Query 224 VAPAHGLTLIQVDYPPDDQLASRNLVTRDVRSG 256 VAPAHGLTLIQVDYPPDDQLASRNLVTRDVRSG Sbjct 121 VAPAHGLTLIQVDYPPDDQLASRNLVTRDVRSG 153 >gi|325675475|ref|ZP_08155159.1| tRNA pseudouridine synthase A [Rhodococcus equi ATCC 33707] gi|325553446|gb|EGD23124.1| tRNA pseudouridine synthase A [Rhodococcus equi ATCC 33707] Length=296 Score = 307 bits (786), Expect = 1e-81, Method: Compositional matrix adjust. Identities = 156/254 (62%), Positives = 189/254 (75%), Gaps = 11/254 (4%) Query 2 GQRTVAGDLDAALTTIFRTPVRLRAAGRTDAGVHASGQVAHVDVPADALPNAYPRAGHVG 61 G+RTV G+++ L+ I RTPV L AGRTDAGVHASGQVAHVDVPAD +P R Sbjct 42 GRRTVCGEIEEKLSAIVRTPVLLTVAGRTDAGVHASGQVAHVDVPADMIPEEPSR----- 96 Query 62 DPEFLPLLRRLGRFLPADVRILDITRAPAGFDARFSALRRHYVYRLSTAPYGVEPQQARY 121 L+RRL RFLP DVR+ ++ AP FDARFSA+RRHY YRL+TAPYG EP +AR Sbjct 97 ------LVRRLARFLPRDVRVKAVSFAPEHFDARFSAIRRHYEYRLTTAPYGAEPLRARD 150 Query 122 ITAWPRELDLDAMTAASRDLMGLHDFAAFCRHREGATTIRDLQRLDWSRAGTLVTAHVTA 181 AWP+++D+DAM AS L+GLHDFAAFC+ REGATT+R+LQR DW ++G +TA V+A Sbjct 151 TVAWPKDVDVDAMRKASSRLLGLHDFAAFCKRREGATTVRELQRFDWEQSGHELTAFVSA 210 Query 182 DAFCWSMVRSLVGALLAVGEHRRATTWCRELLTATGRSSDFAVAPAHGLTLIQVDYPPDD 241 DAFCWSMVRSLVGA LAVGE RR W LL R+S AVAPAHGL+LI+VDYP D+ Sbjct 211 DAFCWSMVRSLVGAALAVGEGRRTVEWMAGLLAERERASAVAVAPAHGLSLIRVDYPADE 270 Query 242 QLASRNLVTRDVRS 255 LA+RN TR++R+ Sbjct 271 DLAARNEATREMRT 284 >gi|312140887|ref|YP_004008223.1| tRNA pseudouridine synthase a [Rhodococcus equi 103S] gi|311890226|emb|CBH49544.1| tRNA pseudouridine synthase A [Rhodococcus equi 103S] Length=274 Score = 306 bits (784), Expect = 2e-81, Method: Compositional matrix adjust. Identities = 156/254 (62%), Positives = 189/254 (75%), Gaps = 11/254 (4%) Query 2 GQRTVAGDLDAALTTIFRTPVRLRAAGRTDAGVHASGQVAHVDVPADALPNAYPRAGHVG 61 G+RTV G+++ L+ I RTPV L AGRTDAGVHASGQVAHVDVPAD +P R Sbjct 20 GRRTVCGEVEEKLSAIVRTPVLLTVAGRTDAGVHASGQVAHVDVPADMIPEEPSR----- 74 Query 62 DPEFLPLLRRLGRFLPADVRILDITRAPAGFDARFSALRRHYVYRLSTAPYGVEPQQARY 121 L+RRL RFLP DVR+ ++ AP FDARFSA+RRHY YRL+TAPYG EP +AR Sbjct 75 ------LVRRLARFLPRDVRVKAVSFAPEHFDARFSAIRRHYEYRLTTAPYGAEPLRARD 128 Query 122 ITAWPRELDLDAMTAASRDLMGLHDFAAFCRHREGATTIRDLQRLDWSRAGTLVTAHVTA 181 AWP+++D+DAM AS L+GLHDFAAFC+ REGATT+R+LQR DW ++G +TA V+A Sbjct 129 TVAWPKDVDVDAMREASSRLLGLHDFAAFCKRREGATTVRELQRFDWEQSGHELTAFVSA 188 Query 182 DAFCWSMVRSLVGALLAVGEHRRATTWCRELLTATGRSSDFAVAPAHGLTLIQVDYPPDD 241 DAFCWSMVRSLVGA LAVGE RR W LL R+S AVAPAHGL+LI+VDYP D+ Sbjct 189 DAFCWSMVRSLVGAALAVGEGRRTVEWMAGLLAERERASAVAVAPAHGLSLIRVDYPADE 248 Query 242 QLASRNLVTRDVRS 255 LA+RN TR++R+ Sbjct 249 DLAARNEATREMRT 262 >gi|111023127|ref|YP_706099.1| pseudouridylate synthase [Rhodococcus jostii RHA1] gi|110822657|gb|ABG97941.1| pseudouridylate synthase [Rhodococcus jostii RHA1] Length=297 Score = 298 bits (763), Expect = 5e-79, Method: Compositional matrix adjust. Identities = 154/254 (61%), Positives = 185/254 (73%), Gaps = 11/254 (4%) Query 2 GQRTVAGDLDAALTTIFRTPVRLRAAGRTDAGVHASGQVAHVDVPADALPNAYPRAGHVG 61 G RTV G+++ L + RTP++L AGRTDAGVHA+GQVAHVDVP DALP+ R Sbjct 47 GLRTVCGEIEEKLGAVLRTPLQLTVAGRTDAGVHATGQVAHVDVPVDALPDDPSR----- 101 Query 62 DPEFLPLLRRLGRFLPADVRILDITRAPAGFDARFSALRRHYVYRLSTAPYGVEPQQARY 121 L+RRL RFLP DVRI I AP FDARFSA+RRHY YRL++A YG +P +AR Sbjct 102 ------LVRRLARFLPKDVRIKRIAFAPEHFDARFSAMRRHYEYRLTSAVYGADPLRARD 155 Query 122 ITAWPRELDLDAMTAASRDLMGLHDFAAFCRHREGATTIRDLQRLDWSRAGTLVTAHVTA 181 ++P+ LDL+ M +AS L+GLHDFAAFC+ REGATT+RDLQR DW R G + TA V+A Sbjct 156 TVSYPKVLDLELMRSASATLLGLHDFAAFCKRREGATTVRDLQRFDWERDGDVFTAFVSA 215 Query 182 DAFCWSMVRSLVGALLAVGEHRRATTWCRELLTATGRSSDFAVAPAHGLTLIQVDYPPDD 241 DAFCWSMVRSLVGA+LAVGE RR W LL RSS VAPAHGL+L++VDYP D Sbjct 216 DAFCWSMVRSLVGAVLAVGEGRRDLGWIEGLLQEKSRSSSILVAPAHGLSLVRVDYPDDA 275 Query 242 QLASRNLVTRDVRS 255 LA+RN +TRDVR+ Sbjct 276 DLAARNKITRDVRT 289 >gi|226365626|ref|YP_002783409.1| tRNA pseudouridine synthase TruA [Rhodococcus opacus B4] gi|226244116|dbj|BAH54464.1| tRNA pseudouridine synthase TruA [Rhodococcus opacus B4] Length=270 Score = 296 bits (757), Expect = 2e-78, Method: Compositional matrix adjust. Identities = 152/254 (60%), Positives = 185/254 (73%), Gaps = 11/254 (4%) Query 2 GQRTVAGDLDAALTTIFRTPVRLRAAGRTDAGVHASGQVAHVDVPADALPNAYPRAGHVG 61 G RTV G+++ L + R+P++L AGRTDAGVHA+GQVAHVDVP +ALP+ R Sbjct 20 GLRTVCGEIEEKLGAVLRSPLQLTVAGRTDAGVHATGQVAHVDVPVEALPDEPSR----- 74 Query 62 DPEFLPLLRRLGRFLPADVRILDITRAPAGFDARFSALRRHYVYRLSTAPYGVEPQQARY 121 L+RRL RFLP DVRI I+ AP FDARFSA+RRHY YRL++A YG +P +AR Sbjct 75 ------LVRRLARFLPKDVRIKQISFAPEHFDARFSAMRRHYEYRLTSAVYGADPLRARD 128 Query 122 ITAWPRELDLDAMTAASRDLMGLHDFAAFCRHREGATTIRDLQRLDWSRAGTLVTAHVTA 181 ++P+ LDL+ M +AS L+GLHDFAAFC+ REGATT+RDLQR DW R G + TA V+A Sbjct 129 TVSYPKILDLELMRSASATLLGLHDFAAFCKRREGATTVRDLQRFDWERDGDVFTAFVSA 188 Query 182 DAFCWSMVRSLVGALLAVGEHRRATTWCRELLTATGRSSDFAVAPAHGLTLIQVDYPPDD 241 DAFCWSMVRSLVGA+LAVGE RR W LL T RSS VAPAHGL L++VDYP Sbjct 189 DAFCWSMVRSLVGAVLAVGEGRRDLDWIEGLLRETSRSSSILVAPAHGLCLVRVDYPEAA 248 Query 242 QLASRNLVTRDVRS 255 LA+RN +TRDVR+ Sbjct 249 DLAARNRITRDVRT 262 >gi|229489482|ref|ZP_04383345.1| tRNA pseudouridine synthase A [Rhodococcus erythropolis SK121] gi|229323579|gb|EEN89337.1| tRNA pseudouridine synthase A [Rhodococcus erythropolis SK121] Length=294 Score = 291 bits (746), Expect = 5e-77, Method: Compositional matrix adjust. Identities = 146/252 (58%), Positives = 184/252 (74%), Gaps = 11/252 (4%) Query 4 RTVAGDLDAALTTIFRTPVRLRAAGRTDAGVHASGQVAHVDVPADALPNAYPRAGHVGDP 63 RTV G+++ L T+ R PV+L AGRTDAGVHA+GQVAHVDVP + LP+ DP Sbjct 44 RTVCGEIEDKLGTVLRRPVQLTVAGRTDAGVHATGQVAHVDVPGELLPD---------DP 94 Query 64 EFLPLLRRLGRFLPADVRILDITRAPAGFDARFSALRRHYVYRLSTAPYGVEPQQARYIT 123 L+RRL RFLP DVR+ I+ P FDARFSA+RR+Y YR++ A +GVEP +AR Sbjct 95 S--RLVRRLARFLPKDVRVKQISVVPGDFDARFSAMRRYYEYRVTNAAFGVEPLRARDTV 152 Query 124 AWPRELDLDAMTAASRDLMGLHDFAAFCRHREGATTIRDLQRLDWSRAGTLVTAHVTADA 183 ++P+ LDL AM AS L+GLH+FAAFC+ REGATT+R+LQR DW++ GT+ TA+V ADA Sbjct 153 SYPKPLDLGAMQEASNRLLGLHNFAAFCKRREGATTVRELQRFDWTQVGTVFTAYVNADA 212 Query 184 FCWSMVRSLVGALLAVGEHRRATTWCRELLTATGRSSDFAVAPAHGLTLIQVDYPPDDQL 243 FCWSMVRSLVGA+L+VGE RR W LL T RSS VAPAHGL+L++VDYP +L Sbjct 213 FCWSMVRSLVGAVLSVGEGRRTADWVAGLLDETSRSSSILVAPAHGLSLVRVDYPDYSEL 272 Query 244 ASRNLVTRDVRS 255 A+RN +TR+ R Sbjct 273 AARNAITRETRE 284 >gi|226305372|ref|YP_002765330.1| tRNA pseudouridine synthase TruA [Rhodococcus erythropolis PR4] gi|226184487|dbj|BAH32591.1| tRNA pseudouridine synthase TruA [Rhodococcus erythropolis PR4] Length=294 Score = 290 bits (741), Expect = 2e-76, Method: Compositional matrix adjust. Identities = 146/252 (58%), Positives = 184/252 (74%), Gaps = 11/252 (4%) Query 4 RTVAGDLDAALTTIFRTPVRLRAAGRTDAGVHASGQVAHVDVPADALPNAYPRAGHVGDP 63 RTV G+++ L T+ R PV+L AGRTDAGVHA+GQVAHVDVP + LP+ DP Sbjct 44 RTVCGEIEDKLGTVLRQPVQLTVAGRTDAGVHATGQVAHVDVPGELLPD---------DP 94 Query 64 EFLPLLRRLGRFLPADVRILDITRAPAGFDARFSALRRHYVYRLSTAPYGVEPQQARYIT 123 L+RRL RFLP DVR+ I+ P FDARFSA+RR+Y YR++ A +GVEP +AR Sbjct 95 S--RLVRRLARFLPKDVRVKQISVVPGDFDARFSAIRRYYEYRVTNAAFGVEPLRARDTV 152 Query 124 AWPRELDLDAMTAASRDLMGLHDFAAFCRHREGATTIRDLQRLDWSRAGTLVTAHVTADA 183 ++P+ LDL AM AS L+GLH+FAAFC+ REGATT+R+LQR DW++ GT+ TA+V ADA Sbjct 153 SYPKPLDLAAMQEASNRLLGLHNFAAFCKRREGATTVRELQRFDWAQEGTVFTAYVNADA 212 Query 184 FCWSMVRSLVGALLAVGEHRRATTWCRELLTATGRSSDFAVAPAHGLTLIQVDYPPDDQL 243 FCWSMVRSLVGA+L+VGE RR W LL T RSS VAPAHGL+L++VDYP +L Sbjct 213 FCWSMVRSLVGAVLSVGEGRRTADWVAGLLDETLRSSSILVAPAHGLSLVRVDYPDYSEL 272 Query 244 ASRNLVTRDVRS 255 A+RN +TR+ R Sbjct 273 AARNAITRETRE 284 >gi|54022806|ref|YP_117048.1| tRNA pseudouridine synthase A [Nocardia farcinica IFM 10152] gi|62901243|sp|Q5Z1K7.1|TRUA_NOCFA RecName: Full=tRNA pseudouridine synthase A; AltName: Full=tRNA pseudouridine(38-40) synthase; AltName: Full=tRNA pseudouridylate synthase I; AltName: Full=tRNA-uridine isomerase I gi|54014314|dbj|BAD55684.1| putative tRNA pseudouridine synthase [Nocardia farcinica IFM 10152] Length=257 Score = 283 bits (723), Expect = 2e-74, Method: Compositional matrix adjust. Identities = 150/254 (60%), Positives = 177/254 (70%), Gaps = 14/254 (5%) Query 2 GQRTVAGDLDAALTTIFRTPVRLRAAGRTDAGVHASGQVAHVDVPADALPNAYPRAGHVG 61 G RTV G L+ AL + R P++L AGRTDAGVHA GQVAH D A+ Sbjct 8 GLRTVQGVLEDALGKVLREPIQLTVAGRTDAGVHAEGQVAHFDTAAE-----------FD 56 Query 62 DPEFLPLLRRLGRFLPADVRILDITRAPAGFDARFSALRRHYVYRLSTAPYGVEPQQARY 121 P+ L+ RL RFLP DVR+ P FDARFSA+RRHYVYRL+TAPYG EP AR Sbjct 57 GPQ---LVHRLARFLPKDVRVKRADVVPPDFDARFSAIRRHYVYRLTTAPYGAEPLAARS 113 Query 122 ITAWPRELDLDAMTAASRDLMGLHDFAAFCRHREGATTIRDLQRLDWSRAGTLVTAHVTA 181 + +D+DAM AS L+GLHDFAAFCR REGATT+R+LQR DW R G L+ AHV+A Sbjct 114 VVPCKSAVDVDAMRRASGLLLGLHDFAAFCRRREGATTVRELQRFDWERQGDLLLAHVSA 173 Query 182 DAFCWSMVRSLVGALLAVGEHRRATTWCRELLTATGRSSDFAVAPAHGLTLIQVDYPPDD 241 DAFCWSMVRSLVGA+LAVGE RR+ W LL T RSS VAPAHGL+L+ VDYP DD Sbjct 174 DAFCWSMVRSLVGAVLAVGEGRRSPEWVAGLLRETQRSSSVTVAPAHGLSLVAVDYPADD 233 Query 242 QLASRNLVTRDVRS 255 +LA+RN+ TR++RS Sbjct 234 ELAARNVQTREMRS 247 >gi|262203538|ref|YP_003274746.1| tRNA pseudouridine synthase A [Gordonia bronchialis DSM 43247] gi|262086885|gb|ACY22853.1| tRNA pseudouridine synthase A [Gordonia bronchialis DSM 43247] Length=291 Score = 278 bits (711), Expect = 5e-73, Method: Compositional matrix adjust. Identities = 149/253 (59%), Positives = 173/253 (69%), Gaps = 7/253 (2%) Query 3 QRTVAGDLDAALTTIFRTPVRLRAAGRTDAGVHASGQVAHVDVPADALPNAYPRAGHVGD 62 QRTV L+ L T+ R PVRL AGRTDAGVHA+GQV H D+P AL GD Sbjct 37 QRTVGAVLEDTLATVLRIPVRLTVAGRTDAGVHATGQVCHTDIPVSALQTRSIG----GD 92 Query 63 PEFLPLLRRLGRFLPADVRILDITRAPAGFDARFSALRRHYVYRLSTAPYGVEPQQARYI 122 P L + RL + LP DVR+ +I FDARFSALRRHY YRL+ A +G EP AR Sbjct 93 PSLL--VGRLAKMLPDDVRVKEIASVSGDFDARFSALRRHYEYRLTDARWGAEPIHARTT 150 Query 123 TAWPRELDLDAMTAASRDLMGLHDFAAFCRHREGATTIRDLQRLDWSR-AGTLVTAHVTA 181 W R LD+DAM AAS L+GL+DFAAFCR REGATTIRDLQ+ W+R AG ++ V+A Sbjct 151 ATWRRPLDVDAMNAASASLLGLNDFAAFCRRREGATTIRDLQQFSWTRHAGGVLVGQVSA 210 Query 182 DAFCWSMVRSLVGALLAVGEHRRATTWCRELLTATGRSSDFAVAPAHGLTLIQVDYPPDD 241 DAFCWSMVRSLVGA+ +VG+ RR WCR LL T RSS VA A GL L++VDYP DD Sbjct 211 DAFCWSMVRSLVGAVASVGDGRRDIDWCRGLLAETQRSSQVPVADACGLCLVRVDYPADD 270 Query 242 QLASRNLVTRDVR 254 +LA RN VTRDVR Sbjct 271 ELAERNTVTRDVR 283 >gi|296394888|ref|YP_003659772.1| tRNA pseudouridine synthase A [Segniliparus rotundus DSM 44985] gi|296182035|gb|ADG98941.1| tRNA pseudouridine synthase A [Segniliparus rotundus DSM 44985] Length=278 Score = 278 bits (711), Expect = 6e-73, Method: Compositional matrix adjust. Identities = 142/254 (56%), Positives = 178/254 (71%), Gaps = 9/254 (3%) Query 2 GQRTVAGDLDAALTTIFRTPVRLRAAGRTDAGVHASGQVAHVDVPADALPNAYPRAGHVG 61 G+RTVAG ++ AL+T+ ++ +L AGRTDAGVHA+GQVAHVDV AD + P Sbjct 30 GRRTVAGVIEEALSTLLQSSAQLTVAGRTDAGVHATGQVAHVDVRADLVSGRLP------ 83 Query 62 DPEFLPLLRRLGRFLPADVRILDITRAPAGFDARFSALRRHYVYRLSTAPYGVEPQQARY 121 PE L+R+L R LP DVR+L + A FDARFSALRRHY Y ++ + YG +P +AR Sbjct 84 -PE--KLVRKLARMLPTDVRVLSAQKVSAQFDARFSALRRHYRYHITRSVYGADPLRARE 140 Query 122 ITAWPRELDLDAMTAASRDLMGLHDFAAFCRHREGATTIRDLQRLDWSRAGTLVTAHVTA 181 + W R LD D + AAS L+GLHDFAAFCR R GATTIR+LQR +W+ +G L+TA +TA Sbjct 141 VVPWARPLDFDVLNAASSALVGLHDFAAFCRPRPGATTIRELQRFEWAESGVLITASITA 200 Query 182 DAFCWSMVRSLVGALLAVGEHRRATTWCRELLTATGRSSDFAVAPAHGLTLIQVDYPPDD 241 DAFCWSM RSLVGA+ AV E RR W R LLTA+ R+S+ VAPAHGL L+ VDYP + Sbjct 201 DAFCWSMCRSLVGAVTAVAEGRRDLAWIRSLLTASSRASEITVAPAHGLCLVGVDYPEES 260 Query 242 QLASRNLVTRDVRS 255 RN TRD+R+ Sbjct 261 AWGIRNEQTRDIRT 274 >gi|317505831|ref|ZP_07963676.1| tRNA pseudouridine synthase [Segniliparus rugosus ATCC BAA-974] gi|316255913|gb|EFV15138.1| tRNA pseudouridine synthase [Segniliparus rugosus ATCC BAA-974] Length=293 Score = 273 bits (698), Expect = 2e-71, Method: Compositional matrix adjust. Identities = 142/254 (56%), Positives = 179/254 (71%), Gaps = 9/254 (3%) Query 2 GQRTVAGDLDAALTTIFRTPVRLRAAGRTDAGVHASGQVAHVDVPADALPNAYPRAGHVG 61 G+RTVAG ++AAL +F+ P +L AGRTD+GVHA+GQVAHVDV A+ + P Sbjct 42 GRRTVAGTIEAALGRLFQAPAQLTVAGRTDSGVHATGQVAHVDVSAELVSGRLP------ 95 Query 62 DPEFLPLLRRLGRFLPADVRILDITRAPAGFDARFSALRRHYVYRLSTAPYGVEPQQARY 121 P+ L+R+L R LP+DVR+L FDARFSALRRHY Y+++ AP+G +P +AR Sbjct 96 -PD--KLVRKLARMLPSDVRVLAAREVSKQFDARFSALRRHYRYQITRAPHGADPLRARE 152 Query 122 ITAWPRELDLDAMTAASRDLMGLHDFAAFCRHREGATTIRDLQRLDWSRAGTLVTAHVTA 181 + W R LDL + AAS L+GLHDFAAFCR R G+TTIR+LQR DW+ G L+TA ++A Sbjct 153 VVPWGRPLDLGLLNAASAALVGLHDFAAFCRPRPGSTTIRELQRFDWTEDGPLLTARISA 212 Query 182 DAFCWSMVRSLVGALLAVGEHRRATTWCRELLTATGRSSDFAVAPAHGLTLIQVDYPPDD 241 DAFCWSM RSL+GA+ AV E RR W LLTA RSS+ AVAP HGL L VDYPP+ Sbjct 213 DAFCWSMCRSLIGAVTAVAEGRREPGWAAALLTAPSRSSEIAVAPGHGLCLTGVDYPPES 272 Query 242 QLASRNLVTRDVRS 255 + A+RNL TRD R+ Sbjct 273 EWAARNLRTRDTRA 286 >gi|296141060|ref|YP_003648303.1| tRNA pseudouridine synthase A [Tsukamurella paurometabola DSM 20162] gi|296029194|gb|ADG79964.1| tRNA pseudouridine synthase A [Tsukamurella paurometabola DSM 20162] Length=273 Score = 270 bits (689), Expect = 2e-70, Method: Compositional matrix adjust. Identities = 148/254 (59%), Positives = 174/254 (69%), Gaps = 16/254 (6%) Query 3 QRTVAGDLDAALTTIFRTPVRLRAAGRTDAGVHASGQVAHVDVPADALPNAYPRAGHVGD 62 +RTV G ++ A+ T+ RTPV+L AGRTDAGVHA+GQVAHVD ALP Sbjct 24 RRTVCGVVEEAIGTVLRTPVQLTVAGRTDAGVHATGQVAHVDTDL-ALPEG--------- 73 Query 63 PEFLPLLRRLGRFLPADVRILDITRAPAGFDARFSALRRHYVYRLSTAPYGVEPQQARYI 122 L+RRL R LP DVR+ I APA FDARFSALRRHY YRL+ APYG P +AR Sbjct 74 -----LVRRLARMLPQDVRVTAIAEAPAEFDARFSALRRHYEYRLTDAPYGANPLRARDT 128 Query 123 TAWPRELDLDAMTAASRDLMGLHDFAAFCRHREGATTIRDLQRLDWSR-AGTLVTAHVTA 181 W R +D++ M AAS L+GLHDFAAFCR REGATT+R+LQR W R A + TA V+A Sbjct 129 APWRRPVDVERMQAASDALLGLHDFAAFCRRREGATTVRELQRFAWRRDADGVCTAEVSA 188 Query 182 DAFCWSMVRSLVGALLAVGEHRRATTWCRELLTATGRSSDFAVAPAHGLTLIQVDYPPDD 241 DAFCWSMVRSLVGA+ AVGE RR+ W LL RSS VA A GLTL++VDYP DD Sbjct 189 DAFCWSMVRSLVGAVAAVGEGRRSVEWVAGLLDERERSSAINVAAACGLTLVRVDYPADD 248 Query 242 QLASRNLVTRDVRS 255 +LA RN +TR+ R Sbjct 249 ELAERNRITREKRE 262 >gi|319950123|ref|ZP_08024062.1| tRNA pseudouridine synthase A [Dietzia cinnamea P4] gi|319436208|gb|EFV91389.1| tRNA pseudouridine synthase A [Dietzia cinnamea P4] Length=380 Score = 269 bits (688), Expect = 3e-70, Method: Compositional matrix adjust. Identities = 154/264 (59%), Positives = 180/264 (69%), Gaps = 17/264 (6%) Query 2 GQRTVAGDLDAALTTIFRTPVRLRAAGRTDAGVHASGQVAHVDVPADALPNAYPRAGHVG 61 G RTV G L+A L+T+ R PV L AGRTDAGVHA QV H+DV P + G Sbjct 25 GLRTVCGVLEAELSTVLRHPVVLTVAGRTDAGVHARAQVCHLDVD----PAWLDQRSLDG 80 Query 62 DPEFLPLLRRLGRFLPADVRILDITRAPAGFDARFSALRRHYVYRLSTAPYGVEPQQARY 121 PE L+RRL R LPAD+ ++D P FDARFSALRRHY YRL+TAP+G EP +AR Sbjct 81 RPE--ALVRRLARLLPADIAVMDGRWVPDEFDARFSALRRHYEYRLTTAPWGAEPIRARD 138 Query 122 ITAWPRELDLDAMTAASRDLMGLHDFAAFCRHREGATTIRDLQRLDWSR----------- 170 AW R DL+A+ AAS L+GLHDFAAFCR REGATTIR+LQR +W Sbjct 139 TAAWTRTADLEAVRAASERLLGLHDFAAFCRRREGATTIRELQRFEWRTEPDPRGPDAPG 198 Query 171 AGTLVTAHVTADAFCWSMVRSLVGALLAVGEHRRATTWCRELLTATGRSSDFAVAPAHGL 230 A + TA V+ADAFCWSMVRSLVGA++AVGE RR+ W LL T RSS VAPA GL Sbjct 199 AAEVWTASVSADAFCWSMVRSLVGAVMAVGEGRRSLEWISGLLAETERSSAVPVAPACGL 258 Query 231 TLIQVDYPPDDQLASRNLVTRDVR 254 +LI VDYP DD+LA+RNLVTR+VR Sbjct 259 SLIGVDYPADDELAARNLVTREVR 282 >gi|326383234|ref|ZP_08204922.1| tRNA pseudouridine synthase A [Gordonia neofelifaecis NRRL B-59395] gi|326197984|gb|EGD55170.1| tRNA pseudouridine synthase A [Gordonia neofelifaecis NRRL B-59395] Length=296 Score = 267 bits (682), Expect = 1e-69, Method: Compositional matrix adjust. Identities = 144/254 (57%), Positives = 175/254 (69%), Gaps = 8/254 (3%) Query 2 GQRTVAGDLDAALTTIFRTPVRLRAAGRTDAGVHASGQVAHVDVPADALPNAYPRAGHV- 60 G+RTV ++ AL T+ R P+RL AGRTDAGVHA+GQVAH DVPA +L R + Sbjct 36 GRRTVCETIEQALGTVLRAPIRLTVAGRTDAGVHAAGQVAHCDVPAASL-----RTRSID 90 Query 61 GDPEFLPLLRRLGRFLPADVRILDITRAPAGFDARFSALRRHYVYRLSTAPYGVEPQQAR 120 GDP L +RRL + LP DVR+ I FDARFSAL R Y YRL+ AP+G EP AR Sbjct 91 GDPARL--VRRLAKMLPDDVRVKRIEAVSEDFDARFSALARTYEYRLTDAPWGAEPTLAR 148 Query 121 YITAWPRELDLDAMTAASRDLMGLHDFAAFCRHREGATTIRDLQRLDWSRAGTLVTAHVT 180 W R LD++AM AS L+GL+DFAAFCR+REG+TTIR+LQR DW R G +V V Sbjct 149 ITADWTRPLDVEAMNTASAGLVGLNDFAAFCRYREGSTTIRELQRFDWRREGPVVVGTVI 208 Query 181 ADAFCWSMVRSLVGALLAVGEHRRATTWCRELLTATGRSSDFAVAPAHGLTLIQVDYPPD 240 ADAFCWSMVRSLVGA+ +VG+ RR+ WC +LL RS+ VA A GL+LI VDYPP Sbjct 209 ADAFCWSMVRSLVGAVASVGDGRRSLGWCTDLLDQRARSAQVPVAQARGLSLIGVDYPPP 268 Query 241 DQLASRNLVTRDVR 254 ++ A+RN TRDVR Sbjct 269 EEWAARNERTRDVR 282 >gi|302330101|gb|ADL20295.1| tRNA pseudouridine synthase A [Corynebacterium pseudotuberculosis 1002] gi|341824210|gb|AEK91731.1| tRNA pseudouridine synthase A [Corynebacterium pseudotuberculosis PAT10] Length=319 Score = 266 bits (681), Expect = 2e-69, Method: Compositional matrix adjust. Identities = 148/257 (58%), Positives = 172/257 (67%), Gaps = 11/257 (4%) Query 4 RTVAGDLDAALTTIFRTPVRLRAAGRTDAGVHASGQVAHVDVPADALPNAYPRAGHVGDP 63 RTV L+ +L I R P++L AGRTDAGVHA+GQVAH DVPA AL GDP Sbjct 61 RTVQRVLEDSLELILRHPIQLTVAGRTDAGVHAAGQVAHFDVPAIALDTRSID----GDP 116 Query 64 EFLPLLRRLGRFLPADVRILDITRAPAGFDARFSALRRHYVYRLSTAPYGVEPQQARYIT 123 L+RRL R LP DVR+ T AP GFDARFSALRRHYVYRL+T P G P +A Sbjct 117 R--NLVRRLARLLPEDVRVHACTLAPEGFDARFSALRRHYVYRLTTHPRGALPTRATDTA 174 Query 124 AWPRELDLDAMTAASRDLMGLHDFAAFCRHREGATTIRDLQRLDWSRAGT-----LVTAH 178 WP+ +D+DAM AA+ L+GLHDFAAFC+HREGATTIRDLQ W T L AH Sbjct 175 HWPKRIDIDAMQAAADVLIGLHDFAAFCKHREGATTIRDLQEFTWHDVSTSLEPQLYEAH 234 Query 179 VTADAFCWSMVRSLVGALLAVGEHRRATTWCRELLTATGRSSDFAVAPAHGLTLIQVDYP 238 VTADAFCWSMVRSLVG+ L +GE +R + LLT T RSS VAPA GL+L+ VDYP Sbjct 235 VTADAFCWSMVRSLVGSCLVIGEGKRPEGFVDSLLTETSRSSQVPVAPAKGLSLVGVDYP 294 Query 239 PDDQLASRNLVTRDVRS 255 D +L +R TR VR+ Sbjct 295 VDSELLARANTTRAVRT 311 >gi|334696185|gb|AEG80982.1| tRNA pseudouridine synthase A [Corynebacterium ulcerans 809] Length=291 Score = 266 bits (679), Expect = 3e-69, Method: Compositional matrix adjust. Identities = 147/257 (58%), Positives = 174/257 (68%), Gaps = 11/257 (4%) Query 4 RTVAGDLDAALTTIFRTPVRLRAAGRTDAGVHASGQVAHVDVPADALPNAYPRAGHVGDP 63 RTV L+ +L I R P++L AGRTDAGVHA+GQVAH DVP AL GDP Sbjct 33 RTVQRVLEDSLELILRHPIQLTVAGRTDAGVHAAGQVAHFDVPEAALDTRSID----GDP 88 Query 64 EFLPLLRRLGRFLPADVRILDITRAPAGFDARFSALRRHYVYRLSTAPYGVEPQQARYIT 123 L+RRL R LP DVR+ TRAP GFDARFSALRRHYVYRL+T P G P +A Sbjct 89 R--NLVRRLARLLPEDVRVHACTRAPEGFDARFSALRRHYVYRLTTHPRGALPTRATDTA 146 Query 124 AWPRELDLDAMTAASRDLMGLHDFAAFCRHREGATTIRDLQRLDWSRAGT-----LVTAH 178 WP+++D++AM AA+ L+GLHDFAAFC++REGATTIRDLQ W T L AH Sbjct 147 HWPKQIDMNAMQAAADVLIGLHDFAAFCKYREGATTIRDLQEFTWHDVSTPLEPQLYEAH 206 Query 179 VTADAFCWSMVRSLVGALLAVGEHRRATTWCRELLTATGRSSDFAVAPAHGLTLIQVDYP 238 VTADAFCWSMVRSLVG+ L +GE +R + LLT T RSS VAPA GL+L+ VDYP Sbjct 207 VTADAFCWSMVRSLVGSCLVIGEGKRPEGFADSLLTETSRSSRVPVAPAKGLSLVGVDYP 266 Query 239 PDDQLASRNLVTRDVRS 255 D +L +R VTR VR+ Sbjct 267 ADSELLARTDVTRAVRT 283 >gi|300857811|ref|YP_003782794.1| tRNA pseudouridine synthase A [Corynebacterium pseudotuberculosis FRC41] gi|300685265|gb|ADK28187.1| tRNA pseudouridine synthase A [Corynebacterium pseudotuberculosis FRC41] gi|302205546|gb|ADL09888.1| tRNA pseudouridine synthase A [Corynebacterium pseudotuberculosis C231] gi|308275782|gb|ADO25681.1| tRNA pseudouridine synthase A [Corynebacterium pseudotuberculosis I19] Length=291 Score = 266 bits (679), Expect = 3e-69, Method: Compositional matrix adjust. Identities = 148/258 (58%), Positives = 172/258 (67%), Gaps = 11/258 (4%) Query 4 RTVAGDLDAALTTIFRTPVRLRAAGRTDAGVHASGQVAHVDVPADALPNAYPRAGHVGDP 63 RTV L+ +L I R P++L AGRTDAGVHA+GQVAH DVPA AL GDP Sbjct 33 RTVQRVLEDSLELILRHPIQLTVAGRTDAGVHAAGQVAHFDVPAIALDTRSID----GDP 88 Query 64 EFLPLLRRLGRFLPADVRILDITRAPAGFDARFSALRRHYVYRLSTAPYGVEPQQARYIT 123 L+RRL R LP DVR+ T AP GFDARFSALRRHYVYRL+T P G P +A Sbjct 89 R--NLVRRLARLLPEDVRVHACTLAPEGFDARFSALRRHYVYRLTTHPRGALPTRATDTA 146 Query 124 AWPRELDLDAMTAASRDLMGLHDFAAFCRHREGATTIRDLQRLDWSRAGT-----LVTAH 178 WP+ +D+DAM AA+ L+GLHDFAAFC+HREGATTIRDLQ W T L AH Sbjct 147 HWPKRIDIDAMQAAADVLIGLHDFAAFCKHREGATTIRDLQEFTWHDVSTSLEPQLYEAH 206 Query 179 VTADAFCWSMVRSLVGALLAVGEHRRATTWCRELLTATGRSSDFAVAPAHGLTLIQVDYP 238 VTADAFCWSMVRSLVG+ L +GE +R + LLT T RSS VAPA GL+L+ VDYP Sbjct 207 VTADAFCWSMVRSLVGSCLVIGEGKRPEGFVDSLLTETSRSSQVPVAPAKGLSLVGVDYP 266 Query 239 PDDQLASRNLVTRDVRSG 256 D +L +R TR VR+ Sbjct 267 VDSELLARANTTRAVRTA 284 >gi|324999254|ref|ZP_08120366.1| tRNA pseudouridine synthase a [Pseudonocardia sp. P1] Length=268 Score = 265 bits (678), Expect = 3e-69, Method: Compositional matrix adjust. Identities = 149/256 (59%), Positives = 174/256 (68%), Gaps = 17/256 (6%) Query 3 QRTVAGDLDAALTTIFRTPVRLRAAGRTDAGVHASGQVAHVDVPADALPNAYPRAGHVGD 62 +RTV G L AL+T+ RTP+RL AGRTDAGVHASGQVAHVDVPA+ D Sbjct 21 RRTVQGVLTDALSTVLRTPLRLTVAGRTDAGVHASGQVAHVDVPAEL------------D 68 Query 63 PEFLPLLRRLGRFLPADVRILDITRAPAGFDARFSALRRHYVYRLSTAPYGVEPQQARYI 122 P+ LLRRL RFLP DVR+ TR P FDARFSALRRHY YR++TA +G EP +AR Sbjct 69 PQLDGLLRRLNRFLPPDVRVRATTRVPETFDARFSALRRHYRYRVTTASFGAEPLRARET 128 Query 123 TAWPRELDLDAMTAASRDLMGLHDFAAFCRHREGATTIRDLQRLDWSRA----GTLVTAH 178 AWP LD M AAS ++G HDFAAFC+ REGATT+R LQR +W A G LV A Sbjct 129 VAWPHPLDPALMNAASALMVGEHDFAAFCKRREGATTVRALQRFEWDPAPGEPGVLV-AS 187 Query 179 VTADAFCWSMVRSLVGALLAVGEHRRATTWCRELLTATGRSSDFAVAPAHGLTLIQVDYP 238 V+ADAFC SMVRSLVGA+ VG R W ELL+ T R+S+ VAP HGL+L VDYP Sbjct 188 VSADAFCHSMVRSLVGAVFEVGRVHRPPEWPAELLSRTSRASEVTVAPPHGLSLTGVDYP 247 Query 239 PDDQLASRNLVTRDVR 254 DD+LA+R TR +R Sbjct 248 ADDELAARAEQTRRIR 263 >gi|337290062|ref|YP_004629083.1| tRNA pseudouridine synthase A [Corynebacterium ulcerans BR-AD22] gi|334698368|gb|AEG83164.1| tRNA pseudouridine synthase A [Corynebacterium ulcerans BR-AD22] Length=291 Score = 264 bits (674), Expect = 1e-68, Method: Compositional matrix adjust. Identities = 146/257 (57%), Positives = 174/257 (68%), Gaps = 11/257 (4%) Query 4 RTVAGDLDAALTTIFRTPVRLRAAGRTDAGVHASGQVAHVDVPADALPNAYPRAGHVGDP 63 RTV L+ +L I R P++L AGRTDAGVHA+GQVAH DVP AL G+P Sbjct 33 RTVQRVLEDSLELILRHPIQLTVAGRTDAGVHAAGQVAHFDVPEAALDTRSID----GNP 88 Query 64 EFLPLLRRLGRFLPADVRILDITRAPAGFDARFSALRRHYVYRLSTAPYGVEPQQARYIT 123 L+RRL R LP DVR+ TRAP GFDARFSALRRHYVYRL+T P G P +A Sbjct 89 R--NLVRRLARLLPEDVRVHACTRAPEGFDARFSALRRHYVYRLTTHPRGALPTRATDTA 146 Query 124 AWPRELDLDAMTAASRDLMGLHDFAAFCRHREGATTIRDLQRLDWSRAGT-----LVTAH 178 WP+++D++AM AA+ L+GLHDFAAFC++REGATTIRDLQ W T L AH Sbjct 147 HWPKQIDMNAMQAAADVLIGLHDFAAFCKYREGATTIRDLQEFTWHDVSTPLEPQLYEAH 206 Query 179 VTADAFCWSMVRSLVGALLAVGEHRRATTWCRELLTATGRSSDFAVAPAHGLTLIQVDYP 238 VTADAFCWSMVRSLVG+ L +GE +R + LLT T RSS VAPA GL+L+ VDYP Sbjct 207 VTADAFCWSMVRSLVGSCLVIGEGKRPEGFADSLLTETSRSSRVPVAPAKGLSLVGVDYP 266 Query 239 PDDQLASRNLVTRDVRS 255 D +L +R VTR VR+ Sbjct 267 ADSELLARADVTRAVRT 283 >gi|258651414|ref|YP_003200570.1| tRNA pseudouridine synthase A [Nakamurella multipartita DSM 44233] gi|258554639|gb|ACV77581.1| tRNA pseudouridine synthase A [Nakamurella multipartita DSM 44233] Length=305 Score = 262 bits (669), Expect = 5e-68, Method: Compositional matrix adjust. Identities = 164/259 (64%), Positives = 187/259 (73%), Gaps = 6/259 (2%) Query 2 GQRTVAGDLDAALTTIFRTPVRLRAAGRTDAGVHASGQVAHVDVPADALPNAYPR--AGH 59 G RTVAG+L +ALTTI RTPVRL AGRTDAGVHA+GQVAHVD+P AL PR A H Sbjct 47 GLRTVAGELTSALTTIVRTPVRLVVAGRTDAGVHAAGQVAHVDLPQAALLTVIPRDRADH 106 Query 60 VGDPE---FLPLLRRLGRFLPADVRILDITRAPAGFDARFSALRRHYVYRLSTAPYGVEP 116 DPE L LLRRLG LP DVR+ + AP GFDARFSALRR Y YR+ TA +GVEP Sbjct 107 -PDPERAGRLGLLRRLGGLLPPDVRVRAVLAAPEGFDARFSALRRRYRYRIGTAEWGVEP 165 Query 117 QQARYITAWPRELDLDAMTAASRDLMGLHDFAAFCRHREGATTIRDLQRLDWSRAGTLVT 176 R++ A R LD++AMT A++ L+GLHDF AFCR REGATTIRDLQ+L +RAG V Sbjct 166 ADRRFVYARRRTLDVEAMTLAAQALVGLHDFHAFCRPREGATTIRDLQKLTVTRAGDEVR 225 Query 177 AHVTADAFCWSMVRSLVGALLAVGEHRRATTWCRELLTATGRSSDFAVAPAHGLTLIQVD 236 V ADAFC SMVR+LVG+LLAVGE R T ELL A R+S FAVAPAHGL+L+ VD Sbjct 226 IDVVADAFCHSMVRALVGSLLAVGELRMPTARPAELLAAGERTSAFAVAPAHGLSLVGVD 285 Query 237 YPPDDQLASRNLVTRDVRS 255 YPP +LA R TR VRS Sbjct 286 YPPPAELARRAHDTRAVRS 304 >gi|284992843|ref|YP_003411397.1| tRNA pseudouridine synthase A [Geodermatophilus obscurus DSM 43160] gi|284066088|gb|ADB77026.1| tRNA pseudouridine synthase A [Geodermatophilus obscurus DSM 43160] Length=282 Score = 256 bits (655), Expect = 2e-66, Method: Compositional matrix adjust. Identities = 144/253 (57%), Positives = 166/253 (66%), Gaps = 11/253 (4%) Query 3 QRTVAGDLDAALTTIFRTPVRLRAAGRTDAGVHASGQVAHVDVPADALPNAYPRAGHVGD 62 QRTV GDL+ AL+ + R PV L AGRTDAGVHA+GQVAH DVP PR Sbjct 41 QRTVQGDLEEALSRVLRQPVSLTVAGRTDAGVHATGQVAHGDVPRAVWAEQRPR------ 94 Query 63 PEFLPLLRRLGRFLPADVRILDITRAPAGFDARFSALRRHYVYRLSTAPYGVEPQQARYI 122 L+RRL LP D+ + + AP FDARF ALRRHYVYRL+ A G P + Sbjct 95 -----LVRRLRGVLPPDIAVHTVEEAPRDFDARFGALRRHYVYRLTDADSGPPPLRRADT 149 Query 123 TAWPRELDLDAMTAASRDLMGLHDFAAFCRHREGATTIRDLQRLDWSRAGTLVTAHVTAD 182 WPR LD DAM A+ L+GLHDFAAFCR REGATTIR L L +R G LVT +AD Sbjct 150 VGWPRRLDADAMAVAAELLLGLHDFAAFCRRREGATTIRTLLTLAVTREGDLVTVRASAD 209 Query 183 AFCWSMVRSLVGALLAVGEHRRATTWCRELLTATGRSSDFAVAPAHGLTLIQVDYPPDDQ 242 AFC SMVRSLVGAL AVGE RR W LLT+T RSS+ V P GLTL+ VDYPPDD+ Sbjct 210 AFCHSMVRSLVGALTAVGEGRRPPEWPAALLTSTERSSEVPVVPPGGLTLVGVDYPPDDE 269 Query 243 LASRNLVTRDVRS 255 LA+R ++TR +RS Sbjct 270 LAARAVLTRGLRS 282 >gi|25027130|ref|NP_737184.1| tRNA pseudouridine synthase A [Corynebacterium efficiens YS-314] gi|23492410|dbj|BAC17384.1| putative tRNA pseudouridine synthase A [Corynebacterium efficiens YS-314] Length=300 Score = 253 bits (647), Expect = 1e-65, Method: Compositional matrix adjust. Identities = 138/256 (54%), Positives = 169/256 (67%), Gaps = 11/256 (4%) Query 4 RTVAGDLDAALTTIFRTPVRLRAAGRTDAGVHASGQVAHVDVPADALPNAYPRAGHVGDP 63 RTV L+ L + R PV L AGRTDAGVHA+GQVAH D+P ++L + GDP Sbjct 44 RTVQKVLEDNLGMVLRAPVELTVAGRTDAGVHAAGQVAHFDIPRESLQ----QRSIDGDP 99 Query 64 EFLPLLRRLGRFLPADVRILDITRAPAGFDARFSALRRHYVYRLSTAPYGVEPQQARYIT 123 L+RRL R LP D+R+ + AP GFDARFSALRRHYVYR++T P G P + R Sbjct 100 T--KLVRRLSRLLPEDIRVHGVNYAPEGFDARFSALRRHYVYRITTHPAGPLPTRVRDTA 157 Query 124 AWPRELDLDAMTAASRDLMGLHDFAAFCRHREGATTIRDLQRLDWSRAGT-----LVTAH 178 AWP+ +D+ AM A+ L+GLHDF AFC+ + A+T+R+LQ W T L AH Sbjct 158 AWPKPVDIQAMQTAADVLIGLHDFVAFCKAKPNASTVRELQEFTWHDVSTPTEPQLYEAH 217 Query 179 VTADAFCWSMVRSLVGALLAVGEHRRATTWCRELLTATGRSSDFAVAPAHGLTLIQVDYP 238 V ADAFCWSMVRSLVG+ +AVGE RRA + +LLTAT RS D VAPA GL+L+ VDYP Sbjct 218 VVADAFCWSMVRSLVGSCMAVGEGRRAGDFTAQLLTATERSPDVPVAPAKGLSLVGVDYP 277 Query 239 PDDQLASRNLVTRDVR 254 DDQL +R TR VR Sbjct 278 DDDQLRARAEETRAVR 293 >gi|255324781|ref|ZP_05365895.1| tRNA pseudouridine synthase A [Corynebacterium tuberculostearicum SK141] gi|255298256|gb|EET77559.1| tRNA pseudouridine synthase A [Corynebacterium tuberculostearicum SK141] Length=297 Score = 253 bits (646), Expect = 2e-65, Method: Compositional matrix adjust. Identities = 144/259 (56%), Positives = 167/259 (65%), Gaps = 11/259 (4%) Query 2 GQRTVAGDLDAALTTIFRTPVRLRAAGRTDAGVHASGQVAHVDVPADALPNAYPRAGHVG 61 G RTV G L+ L I RT V L AGRTDAGVHA GQVAHVDVP + L AG G Sbjct 43 GLRTVQGVLEEKLAMIARTEVPLTVAGRTDAGVHARGQVAHVDVPTEMLAQ-RSVAGEPG 101 Query 62 DPEFLPLLRRLGRFLPADVRILDITRAPAGFDARFSALRRHYVYRLSTAPYGVEPQQARY 121 L+RRL + LP DVR+ APAGFDARFSALRRHYVYR++T P G P +AR Sbjct 102 K-----LVRRLAKLLPEDVRVHGCEFAPAGFDARFSALRRHYVYRITTNPRGALPTRARD 156 Query 122 ITAWPRELDLDAMTAASRDLMGLHDFAAFCRHREGATTIRDLQRLDWSRAGT-----LVT 176 W + +D+DAM A+ L+GLHDFAAFC+ + ATTIR+LQ W T L Sbjct 157 TAEWIKPVDIDAMQEAATALVGLHDFAAFCKAKPNATTIRELQEFSWRDVSTPEEPELYE 216 Query 177 AHVTADAFCWSMVRSLVGALLAVGEHRRATTWCRELLTATGRSSDFAVAPAHGLTLIQVD 236 A V+ADAFCWSMVRSLVG L VGE RR T + LL T RSS VAPA GL+L+ VD Sbjct 217 ARVSADAFCWSMVRSLVGCCLRVGEGRRDTDFAAALLQETKRSSSIPVAPAKGLSLVAVD 276 Query 237 YPPDDQLASRNLVTRDVRS 255 YP D+LA+R VTR+ RS Sbjct 277 YPAADKLAARAEVTRERRS 295 >gi|259506738|ref|ZP_05749638.1| tRNA pseudouridine synthase A [Corynebacterium efficiens YS-314] gi|42559821|sp|Q8FS31.2|TRUA_COREF RecName: Full=tRNA pseudouridine synthase A; AltName: Full=tRNA pseudouridine(38-40) synthase; AltName: Full=tRNA pseudouridylate synthase I; AltName: Full=tRNA-uridine isomerase I gi|259165679|gb|EEW50233.1| tRNA pseudouridine synthase A [Corynebacterium efficiens YS-314] Length=282 Score = 253 bits (645), Expect = 2e-65, Method: Compositional matrix adjust. Identities = 138/256 (54%), Positives = 169/256 (67%), Gaps = 11/256 (4%) Query 4 RTVAGDLDAALTTIFRTPVRLRAAGRTDAGVHASGQVAHVDVPADALPNAYPRAGHVGDP 63 RTV L+ L + R PV L AGRTDAGVHA+GQVAH D+P ++L + GDP Sbjct 26 RTVQKVLEDNLGMVLRAPVELTVAGRTDAGVHAAGQVAHFDIPRESLQ----QRSIDGDP 81 Query 64 EFLPLLRRLGRFLPADVRILDITRAPAGFDARFSALRRHYVYRLSTAPYGVEPQQARYIT 123 L+RRL R LP D+R+ + AP GFDARFSALRRHYVYR++T P G P + R Sbjct 82 --TKLVRRLSRLLPEDIRVHGVNYAPEGFDARFSALRRHYVYRITTHPAGPLPTRVRDTA 139 Query 124 AWPRELDLDAMTAASRDLMGLHDFAAFCRHREGATTIRDLQRLDWSRAGT-----LVTAH 178 AWP+ +D+ AM A+ L+GLHDF AFC+ + A+T+R+LQ W T L AH Sbjct 140 AWPKPVDIQAMQTAADVLIGLHDFVAFCKAKPNASTVRELQEFTWHDVSTPTEPQLYEAH 199 Query 179 VTADAFCWSMVRSLVGALLAVGEHRRATTWCRELLTATGRSSDFAVAPAHGLTLIQVDYP 238 V ADAFCWSMVRSLVG+ +AVGE RRA + +LLTAT RS D VAPA GL+L+ VDYP Sbjct 200 VVADAFCWSMVRSLVGSCMAVGEGRRAGDFTAQLLTATERSPDVPVAPAKGLSLVGVDYP 259 Query 239 PDDQLASRNLVTRDVR 254 DDQL +R TR VR Sbjct 260 DDDQLRARAEETRAVR 275 >gi|296119322|ref|ZP_06837890.1| tRNA pseudouridine synthase A [Corynebacterium ammoniagenes DSM 20306] gi|295967714|gb|EFG80971.1| tRNA pseudouridine synthase A [Corynebacterium ammoniagenes DSM 20306] Length=297 Score = 252 bits (644), Expect = 3e-65, Method: Compositional matrix adjust. Identities = 137/258 (54%), Positives = 166/258 (65%), Gaps = 11/258 (4%) Query 4 RTVAGDLDAALTTIFRTPVRLRAAGRTDAGVHASGQVAHVDVPADALPNAYPRAGHVGDP 63 RTV G L+ LT I R P+ L AGRTDAGVHA+GQVAH DVP ++L D Sbjct 39 RTVQGVLEQCLTMILRHPIELTVAGRTDAGVHAAGQVAHADVPVESLQQ------RSIDG 92 Query 64 EFLPLLRRLGRFLPADVRILDITRAPAGFDARFSALRRHYVYRLSTAPYGVEPQQARYIT 123 E L+RRL + + D+RI ++ AP GFDARFSALRRHYVYR++T G P + R Sbjct 93 EPAKLVRRLAKLVDDDIRIHSVSFAPEGFDARFSALRRHYVYRITTEEAGALPTRLRDTA 152 Query 124 AWPRELDLDAMTAASRDLMGLHDFAAFCRHREGATTIRDLQRLDWSRAGT-----LVTAH 178 W R +D+D M A+ L+GLHDFAAFC+ + ATTIRDLQ W A T L AH Sbjct 153 TWTRPVDIDLMQQAATTLVGLHDFAAFCKAKPHATTIRDLQEFYWVDASTPSEPNLYEAH 212 Query 179 VTADAFCWSMVRSLVGALLAVGEHRRATTWCRELLTATGRSSDFAVAPAHGLTLIQVDYP 238 V+ADAFCWSMVRSLVG LAVGE RR + +L + RSS VA A GL+L+ VDYP Sbjct 213 VSADAFCWSMVRSLVGCCLAVGEGRRDINFVEAMLGESERSSSIPVAAAKGLSLVGVDYP 272 Query 239 PDDQLASRNLVTRDVRSG 256 D+ LA+R +VTRD RS Sbjct 273 ADEDLAARTMVTRDKRSA 290 >gi|260579203|ref|ZP_05847093.1| tRNA pseudouridine synthase A [Corynebacterium jeikeium ATCC 43734] gi|258602689|gb|EEW15976.1| tRNA pseudouridine synthase A [Corynebacterium jeikeium ATCC 43734] Length=328 Score = 252 bits (644), Expect = 3e-65, Method: Compositional matrix adjust. Identities = 142/259 (55%), Positives = 168/259 (65%), Gaps = 12/259 (4%) Query 2 GQRTVAGDLDAALTTIFRTPVRLRAAGRTDAGVHASGQVAHVDVPADALPNAYPRAGHVG 61 G RTVAG L L+ + R P+ L AGRTDAGVHASGQV H D+PADA + Sbjct 51 GLRTVAGVLQEKLSLVTRHPIELVVAGRTDAGVHASGQVCHADIPADAFEQR-----SLT 105 Query 62 DPEFLPLLRRLGRFLPADVRILDITRAPAGFDARFSALRRHYVYRLSTAPYGVEPQQARY 121 PE L+RRL R LP+DVR+ + AP GFDARFSALRRHY+YR++T P G P +AR Sbjct 106 RPE--DLVRRLSRMLPSDVRLHGASVAPQGFDARFSALRRHYIYRVTTHPAGPVPVRARD 163 Query 122 ITAWPRELDLDAMTAASRDLMGLHDFAAFCRHREGATTIRDLQRLDWSRAGT-----LVT 176 AW +DL+ AAS L+GL+DFAAFC+ REGATT+R+LQ W T Sbjct 164 TAAWRHPIDLEKTQAASDALIGLNDFAAFCKAREGATTVRELQEFRWVDVSTEAEPQTYE 223 Query 177 AHVTADAFCWSMVRSLVGALLAVGEHRRATTWCRELLTATGRSSDFAVAPAHGLTLIQVD 236 AHVTADAFCWSMVRSLVGA L VG +R + LL T RSS VAPA GL L++VD Sbjct 224 AHVTADAFCWSMVRSLVGAALTVGSGKRPDDFTPGLLKETKRSSAVPVAPAEGLNLVRVD 283 Query 237 YPPDDQLASRNLVTRDVRS 255 YP D++LA R L TR RS Sbjct 284 YPADEELAERALTTRAKRS 302 Lambda K H 0.324 0.137 0.422 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 377837056800 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40