BLASTP 2.2.25+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.



Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
           15,229,318 sequences; 5,219,829,388 total letters



Query= Rv3464

Length=331
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

gi|15610600|ref|NP_217981.1|  dTDP-glucose 4,6-dehydratase RMLB [...   676    0.0   
gi|298526948|ref|ZP_07014357.1|  dtdp-glucose 4,6-dehydratase rml...   673    0.0   
gi|340628435|ref|YP_004746887.1|  dTDP-glucose 4,6-dehydratase RM...   672    0.0   
gi|118616617|ref|YP_904949.1|  dTDP-glucose-4,6-dehydratase, RmlB...   637    0.0   
gi|41410323|ref|NP_963159.1|  RmlB [Mycobacterium avium subsp. pa...   631    4e-179
gi|342861859|ref|ZP_08718504.1|  dTDP-glucose 4,6-dehydratase [My...   631    6e-179
gi|254819211|ref|ZP_05224212.1|  dTDP-glucose 4,6-dehydratase [My...   629    2e-178
gi|296168675|ref|ZP_06850424.1|  dTDP-glucose-4,6-dehydratase [My...   628    4e-178
gi|2326950|gb|AAB66648.1|  rhamnose biosynthesis protein [Mycobac...   615    3e-174
gi|240167775|ref|ZP_04746434.1|  dTDP-glucose 4,6-dehydratase [My...   594    8e-168
gi|15828065|ref|NP_302328.1|  dTDP-glucose 4,6-dehydratase [Mycob...   585    4e-165
gi|4539118|emb|CAB39839.1|  putative dTDP-(glucose or rhamnose)-4...   585    4e-165
gi|118467903|ref|YP_885894.1|  dTDP-glucose 4,6-dehydratase [Myco...   573    1e-161
gi|108798039|ref|YP_638236.1|  dTDP-glucose 4,6-dehydratase [Myco...   561    5e-158
gi|126433700|ref|YP_001069391.1|  dTDP-glucose 4,6-dehydratase [M...   559    2e-157
gi|120402376|ref|YP_952205.1|  dTDP-glucose 4,6-dehydratase [Myco...   539    2e-151
gi|333991927|ref|YP_004524541.1|  dTDP-glucose-46-dehydratase Rml...   530    9e-149
gi|145225583|ref|YP_001136261.1|  dTDP-glucose 4,6-dehydratase [M...   528    4e-148
gi|315445936|ref|YP_004078815.1|  dTDP-glucose 4,6-dehydratase [M...   525    4e-147
gi|169630859|ref|YP_001704508.1|  dTDP-glucose 4,6-dehydratase Rm...   525    5e-147
gi|325673207|ref|ZP_08152900.1|  dTDP-glucose-4,6-dehydratase [Rh...   508    5e-142
gi|269957347|ref|YP_003327136.1|  dTDP-glucose 4,6-dehydratase [X...   506    3e-141
gi|334337869|ref|YP_004543021.1|  dTDP-glucose 4,6-dehydratase [I...   501    5e-140
gi|269794222|ref|YP_003313677.1|  dTDP-glucose 4,6-dehydratase [S...   494    6e-138
gi|323357014|ref|YP_004223410.1|  dTDP-D-glucose 4,6-dehydratase ...   483    1e-134
gi|226303739|ref|YP_002763697.1|  dTDP-glucose 4,6-dehydratase [R...   482    3e-134
gi|256856008|emb|CBB12353.1|  RmlB protein [Rhodococcus aetherivo...   481    6e-134
gi|229492624|ref|ZP_04386427.1|  dTDP-glucose 4,6-dehydratase [Rh...   481    7e-134
gi|311742182|ref|ZP_07715992.1|  dTDP-glucose 4,6-dehydratase [Ae...   480    1e-133
gi|257067485|ref|YP_003153740.1|  dTDP-glucose 4,6-dehydratase [B...   477    1e-132
gi|333917811|ref|YP_004491392.1|  dTDP-glucose 4,6-dehydratase [A...   476    3e-132
gi|255327300|ref|ZP_05368374.1|  dTDP-glucose 4,6-dehydratase [Ro...   475    4e-132
gi|309812220|ref|ZP_07705978.1|  dTDP-glucose 4,6-dehydratase [De...   474    7e-132
gi|111021081|ref|YP_704053.1|  dTDP-glucose 4,6-dehydratase [Rhod...   474    1e-131
gi|283458591|ref|YP_003363224.1|  dTDP-D-glucose 4,6-dehydratase ...   473    1e-131
gi|84498710|ref|ZP_00997451.1|  putative dTDP-D-glucose 4,6-dehyd...   473    2e-131
gi|226363371|ref|YP_002781153.1|  dTDP-glucose 4,6-dehydratase [R...   473    2e-131
gi|145223883|ref|YP_001134561.1|  dTDP-glucose 4,6-dehydratase [M...   473    2e-131
gi|125625378|dbj|BAF46773.1|  Putative dTDP-glucose-4,6-dehydrata...   471    9e-131
gi|313141151|ref|ZP_07803344.1|  DTDP-glucose 4,6-dehydratase enz...   470    1e-130
gi|225352523|ref|ZP_03743546.1|  hypothetical protein BIFPSEUDO_0...   469    2e-130
gi|300743860|ref|ZP_07072880.1|  dTDP-glucose 4,6-dehydratase [Ro...   469    3e-130
gi|310286572|ref|YP_003937830.1|  dTDP-glucose 4,6-dehydratase in...   469    3e-130
gi|311113105|ref|YP_003984327.1|  dTDP-glucose 4,6-dehydratase [R...   469    4e-130
gi|296130221|ref|YP_003637471.1|  dTDP-glucose 4,6-dehydratase [C...   467    9e-130
gi|289704884|ref|ZP_06501301.1|  dTDP-glucose 4,6-dehydratase [Mi...   467    1e-129
gi|139439924|ref|ZP_01773276.1|  Hypothetical protein COLAER_0231...   467    1e-129
gi|116671225|ref|YP_832158.1|  dTDP-glucose 4,6-dehydratase [Arth...   467    1e-129
gi|119026525|ref|YP_910370.1|  rhamnose biosynthesis dTDP-glucose...   465    4e-129
gi|319949394|ref|ZP_08023460.1|  dTDP-glucose 4,6-dehydratase [Di...   465    5e-129


>gi|15610600|ref|NP_217981.1| dTDP-glucose 4,6-dehydratase RMLB [Mycobacterium tuberculosis 
H37Rv]
 gi|15843059|ref|NP_338096.1| dTDP-glucose-4,6-dehydratase [Mycobacterium tuberculosis CDC1551]
 gi|31794640|ref|NP_857133.1| dTDP-glucose 4,6-dehydratase RmlB1 [Mycobacterium bovis AF2122/97]
 75 more sequence titles
 Length=331

 Score =  676 bits (1744),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 331/331 (100%), Positives = 331/331 (100%), Gaps = 0/331 (0%)

Query  1    MRLLVTGGAGFIGTNFVHSAVREHPDDAVTVLDALTYAGRRESLADVEDAIRLVQGDITD  60
            MRLLVTGGAGFIGTNFVHSAVREHPDDAVTVLDALTYAGRRESLADVEDAIRLVQGDITD
Sbjct  1    MRLLVTGGAGFIGTNFVHSAVREHPDDAVTVLDALTYAGRRESLADVEDAIRLVQGDITD  60

Query  61   AELVSQLVAESDAVVHFAAESHVDNALDNPEPFLHTNVIGTFTILEAVRRHGVRLHHIST  120
            AELVSQLVAESDAVVHFAAESHVDNALDNPEPFLHTNVIGTFTILEAVRRHGVRLHHIST
Sbjct  61   AELVSQLVAESDAVVHFAAESHVDNALDNPEPFLHTNVIGTFTILEAVRRHGVRLHHIST  120

Query  121  DEVYGDLELDDRARFTESTPYNPSSPYSATKAGADMLVRAWVRSYGVRATISNCSNNYGP  180
            DEVYGDLELDDRARFTESTPYNPSSPYSATKAGADMLVRAWVRSYGVRATISNCSNNYGP
Sbjct  121  DEVYGDLELDDRARFTESTPYNPSSPYSATKAGADMLVRAWVRSYGVRATISNCSNNYGP  180

Query  181  YQHVEKFIPRQITNVLTGRRPKLYGAGANVRDWIHVDDHNSAVRRILDRGRIGRTYLISS  240
            YQHVEKFIPRQITNVLTGRRPKLYGAGANVRDWIHVDDHNSAVRRILDRGRIGRTYLISS
Sbjct  181  YQHVEKFIPRQITNVLTGRRPKLYGAGANVRDWIHVDDHNSAVRRILDRGRIGRTYLISS  240

Query  241  EGERDNLTVLRTLLRLMDRDPDDFDHVTDRVGHDLRYAIDPSTLYDELCWAPKHTDFEEG  300
            EGERDNLTVLRTLLRLMDRDPDDFDHVTDRVGHDLRYAIDPSTLYDELCWAPKHTDFEEG
Sbjct  241  EGERDNLTVLRTLLRLMDRDPDDFDHVTDRVGHDLRYAIDPSTLYDELCWAPKHTDFEEG  300

Query  301  LRTTIDWYRDNESWWRPLKDATEARYQERGQ  331
            LRTTIDWYRDNESWWRPLKDATEARYQERGQ
Sbjct  301  LRTTIDWYRDNESWWRPLKDATEARYQERGQ  331


>gi|298526948|ref|ZP_07014357.1| dtdp-glucose 4,6-dehydratase rmlb [Mycobacterium tuberculosis 
94_M4241A]
 gi|298496742|gb|EFI32036.1| dtdp-glucose 4,6-dehydratase rmlb [Mycobacterium tuberculosis 
94_M4241A]
Length=331

 Score =  673 bits (1737),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 330/331 (99%), Positives = 330/331 (99%), Gaps = 0/331 (0%)

Query  1    MRLLVTGGAGFIGTNFVHSAVREHPDDAVTVLDALTYAGRRESLADVEDAIRLVQGDITD  60
            MRLLVTGGAGFIGTNFVHSAVREHPDDAVTVLDALTYAGRRESLADVEDAIRLVQGDITD
Sbjct  1    MRLLVTGGAGFIGTNFVHSAVREHPDDAVTVLDALTYAGRRESLADVEDAIRLVQGDITD  60

Query  61   AELVSQLVAESDAVVHFAAESHVDNALDNPEPFLHTNVIGTFTILEAVRRHGVRLHHIST  120
            AELVSQLVAESDAVVHFAAESHVDNALDNPEPFLHTNVIGTFTILEAVRRHGVRLHHIST
Sbjct  61   AELVSQLVAESDAVVHFAAESHVDNALDNPEPFLHTNVIGTFTILEAVRRHGVRLHHIST  120

Query  121  DEVYGDLELDDRARFTESTPYNPSSPYSATKAGADMLVRAWVRSYGVRATISNCSNNYGP  180
            DEVYGDLELDDRARFTESTPYNPSSPYSATKAGADMLVRAWVRSYGV ATISNCSNNYGP
Sbjct  121  DEVYGDLELDDRARFTESTPYNPSSPYSATKAGADMLVRAWVRSYGVGATISNCSNNYGP  180

Query  181  YQHVEKFIPRQITNVLTGRRPKLYGAGANVRDWIHVDDHNSAVRRILDRGRIGRTYLISS  240
            YQHVEKFIPRQITNVLTGRRPKLYGAGANVRDWIHVDDHNSAVRRILDRGRIGRTYLISS
Sbjct  181  YQHVEKFIPRQITNVLTGRRPKLYGAGANVRDWIHVDDHNSAVRRILDRGRIGRTYLISS  240

Query  241  EGERDNLTVLRTLLRLMDRDPDDFDHVTDRVGHDLRYAIDPSTLYDELCWAPKHTDFEEG  300
            EGERDNLTVLRTLLRLMDRDPDDFDHVTDRVGHDLRYAIDPSTLYDELCWAPKHTDFEEG
Sbjct  241  EGERDNLTVLRTLLRLMDRDPDDFDHVTDRVGHDLRYAIDPSTLYDELCWAPKHTDFEEG  300

Query  301  LRTTIDWYRDNESWWRPLKDATEARYQERGQ  331
            LRTTIDWYRDNESWWRPLKDATEARYQERGQ
Sbjct  301  LRTTIDWYRDNESWWRPLKDATEARYQERGQ  331


>gi|340628435|ref|YP_004746887.1| dTDP-glucose 4,6-dehydratase RMLB [Mycobacterium canettii CIPT 
140010059]
 gi|340006625|emb|CCC45812.1| dTDP-glucose 4,6-dehydratase RMLB [Mycobacterium canettii CIPT 
140010059]
Length=331

 Score =  672 bits (1733),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 329/331 (99%), Positives = 329/331 (99%), Gaps = 0/331 (0%)

Query  1    MRLLVTGGAGFIGTNFVHSAVREHPDDAVTVLDALTYAGRRESLADVEDAIRLVQGDITD  60
            MRLLVTGGAGFIGTNFVHSAVREHPDDAVTVLDALTYAGRRESLADVEDAIRLVQGDITD
Sbjct  1    MRLLVTGGAGFIGTNFVHSAVREHPDDAVTVLDALTYAGRRESLADVEDAIRLVQGDITD  60

Query  61   AELVSQLVAESDAVVHFAAESHVDNALDNPEPFLHTNVIGTFTILEAVRRHGVRLHHIST  120
            AELVSQLVAESDAVVHFAAESHVDNALDNPEPFLHTNVIGTFTILEAVRRHGVRLHHIST
Sbjct  61   AELVSQLVAESDAVVHFAAESHVDNALDNPEPFLHTNVIGTFTILEAVRRHGVRLHHIST  120

Query  121  DEVYGDLELDDRARFTESTPYNPSSPYSATKAGADMLVRAWVRSYGVRATISNCSNNYGP  180
            DEVYGDLELDD ARFTESTPYNPSSPYSATKAGADMLVRAWVRSYGVRATISNCSNNYGP
Sbjct  121  DEVYGDLELDDPARFTESTPYNPSSPYSATKAGADMLVRAWVRSYGVRATISNCSNNYGP  180

Query  181  YQHVEKFIPRQITNVLTGRRPKLYGAGANVRDWIHVDDHNSAVRRILDRGRIGRTYLISS  240
            YQHVEKFIPRQITNVLTGRRPKLYGAGANVRDWIHVDDHNSAVRRILDRGRIGRTYLISS
Sbjct  181  YQHVEKFIPRQITNVLTGRRPKLYGAGANVRDWIHVDDHNSAVRRILDRGRIGRTYLISS  240

Query  241  EGERDNLTVLRTLLRLMDRDPDDFDHVTDRVGHDLRYAIDPSTLYDELCWAPKHTDFEEG  300
            EGERDNLTVLRTLLRLMDRDPDDFDHVTDRVGHDLRYAIDPSTLYDELCWAPKHTDFEEG
Sbjct  241  EGERDNLTVLRTLLRLMDRDPDDFDHVTDRVGHDLRYAIDPSTLYDELCWAPKHTDFEEG  300

Query  301  LRTTIDWYRDNESWWRPLKDATEARYQERGQ  331
            LRTTIDWYRDNESWWRPLKD TEARYQERGQ
Sbjct  301  LRTTIDWYRDNESWWRPLKDVTEARYQERGQ  331


>gi|118616617|ref|YP_904949.1| dTDP-glucose-4,6-dehydratase, RmlB [Mycobacterium ulcerans Agy99]
 gi|183981102|ref|YP_001849393.1| dTDP-glucose-4,6-dehydratase, RmlB [Mycobacterium marinum M]
 gi|118568727|gb|ABL03478.1| dTDP-glucose-4,6-dehydratase, RmlB [Mycobacterium ulcerans Agy99]
 gi|183174428|gb|ACC39538.1| dTDP-glucose-4,6-dehydratase, RmlB [Mycobacterium marinum M]
Length=331

 Score =  637 bits (1644),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 306/331 (93%), Positives = 321/331 (97%), Gaps = 0/331 (0%)

Query  1    MRLLVTGGAGFIGTNFVHSAVREHPDDAVTVLDALTYAGRRESLADVEDAIRLVQGDITD  60
            MRLLVTGGAGFIG NFVHS+VRE+PDDAVTVLDALTYAGRRESLAD+EDAIRLV+GDITD
Sbjct  1    MRLLVTGGAGFIGANFVHSSVREYPDDAVTVLDALTYAGRRESLADLEDAIRLVEGDITD  60

Query  61   AELVSQLVAESDAVVHFAAESHVDNALDNPEPFLHTNVIGTFTILEAVRRHGVRLHHIST  120
            AELVSQLVAESDAVVHFAAESHVDNALDNPEPF+HTNV+GTFTILEAVRRHGVRLHHIST
Sbjct  61   AELVSQLVAESDAVVHFAAESHVDNALDNPEPFVHTNVLGTFTILEAVRRHGVRLHHIST  120

Query  121  DEVYGDLELDDRARFTESTPYNPSSPYSATKAGADMLVRAWVRSYGVRATISNCSNNYGP  180
            DEVYGDLEL D ARFTE+TPYNPSSPYSATKAGADMLVRAWVRSYGV ATISNCSNNYGP
Sbjct  121  DEVYGDLELHDPARFTEATPYNPSSPYSATKAGADMLVRAWVRSYGVAATISNCSNNYGP  180

Query  181  YQHVEKFIPRQITNVLTGRRPKLYGAGANVRDWIHVDDHNSAVRRILDRGRIGRTYLISS  240
            YQH+EKFIPRQITNVLTGRRPKLYG GANVRDWIHVDDHNSAVRRIL++G+IG+TYLISS
Sbjct  181  YQHIEKFIPRQITNVLTGRRPKLYGTGANVRDWIHVDDHNSAVRRILEKGQIGKTYLISS  240

Query  241  EGERDNLTVLRTLLRLMDRDPDDFDHVTDRVGHDLRYAIDPSTLYDELCWAPKHTDFEEG  300
            EGERDNL+VLRTLLR+MDRDPDDFDHV DRVGHDLRYAIDPS LY+EL WAPKHTDFEEG
Sbjct  241  EGERDNLSVLRTLLRMMDRDPDDFDHVVDRVGHDLRYAIDPSLLYNELAWAPKHTDFEEG  300

Query  301  LRTTIDWYRDNESWWRPLKDATEARYQERGQ  331
            LRTTIDWYR NESWWRPLKDA EARYQERGQ
Sbjct  301  LRTTIDWYRANESWWRPLKDAAEARYQERGQ  331


>gi|41410323|ref|NP_963159.1| RmlB [Mycobacterium avium subsp. paratuberculosis K-10]
 gi|118466831|ref|YP_883541.1| dTDP-glucose 4,6-dehydratase [Mycobacterium avium 104]
 gi|254776838|ref|ZP_05218354.1| dTDP-glucose 4,6-dehydratase [Mycobacterium avium subsp. avium 
ATCC 25291]
 gi|41399157|gb|AAS06775.1| RmlB [Mycobacterium avium subsp. paratuberculosis K-10]
 gi|118168118|gb|ABK69015.1| dTDP-glucose 4,6-dehydratase [Mycobacterium avium 104]
 gi|336460711|gb|EGO39601.1| dTDP-glucose 4,6-dehydratase [Mycobacterium avium subsp. paratuberculosis 
S397]
Length=331

 Score =  631 bits (1628),  Expect = 4e-179, Method: Compositional matrix adjust.
 Identities = 306/331 (93%), Positives = 316/331 (96%), Gaps = 0/331 (0%)

Query  1    MRLLVTGGAGFIGTNFVHSAVREHPDDAVTVLDALTYAGRRESLADVEDAIRLVQGDITD  60
            MRLLVTGGAGFIG NFVHS VREHP+D+VTVLDALTYAGRRESLA VED+IRLV GDITD
Sbjct  1    MRLLVTGGAGFIGANFVHSTVREHPEDSVTVLDALTYAGRRESLAGVEDSIRLVVGDITD  60

Query  61   AELVSQLVAESDAVVHFAAESHVDNALDNPEPFLHTNVIGTFTILEAVRRHGVRLHHIST  120
            AELVS+LVAESDAVVHFAAESHVDNAL  PEPFLHTNV+GTFTILEAVRRHGVRLHHIST
Sbjct  61   AELVSRLVAESDAVVHFAAESHVDNALAGPEPFLHTNVVGTFTILEAVRRHGVRLHHIST  120

Query  121  DEVYGDLELDDRARFTESTPYNPSSPYSATKAGADMLVRAWVRSYGVRATISNCSNNYGP  180
            DEVYGDLELDD  RFTESTPYNPSSPYSATKA ADMLVRAWVRSYGVRATISNCSNNYGP
Sbjct  121  DEVYGDLELDDPNRFTESTPYNPSSPYSATKAAADMLVRAWVRSYGVRATISNCSNNYGP  180

Query  181  YQHVEKFIPRQITNVLTGRRPKLYGAGANVRDWIHVDDHNSAVRRILDRGRIGRTYLISS  240
            YQHVEKFIPRQITNVLTGRRPKLYG GANVRDWIHVDDHNSAVRRIL+ G IGRTYLISS
Sbjct  181  YQHVEKFIPRQITNVLTGRRPKLYGTGANVRDWIHVDDHNSAVRRILESGEIGRTYLISS  240

Query  241  EGERDNLTVLRTLLRLMDRDPDDFDHVTDRVGHDLRYAIDPSTLYDELCWAPKHTDFEEG  300
            EGERDNLTVLRTLL++M RDPDDFDHVTDRVGHDLRYAIDPSTLYDELCWAPKHTDFEEG
Sbjct  241  EGERDNLTVLRTLLQMMGRDPDDFDHVTDRVGHDLRYAIDPSTLYDELCWAPKHTDFEEG  300

Query  301  LRTTIDWYRDNESWWRPLKDATEARYQERGQ  331
            LR TIDWYR NESWWRPLKDA+EARY+ERGQ
Sbjct  301  LRETIDWYRANESWWRPLKDASEARYEERGQ  331


>gi|342861859|ref|ZP_08718504.1| dTDP-glucose 4,6-dehydratase [Mycobacterium colombiense CECT 
3035]
 gi|342130676|gb|EGT83980.1| dTDP-glucose 4,6-dehydratase [Mycobacterium colombiense CECT 
3035]
Length=331

 Score =  631 bits (1627),  Expect = 6e-179, Method: Compositional matrix adjust.
 Identities = 303/331 (92%), Positives = 318/331 (97%), Gaps = 0/331 (0%)

Query  1    MRLLVTGGAGFIGTNFVHSAVREHPDDAVTVLDALTYAGRRESLADVEDAIRLVQGDITD  60
            MRLLVTGGAGFIG NFVHS VREHP+D+VTVLDA+TYAGRRESLADVED+I LV GDITD
Sbjct  1    MRLLVTGGAGFIGANFVHSTVREHPEDSVTVLDAMTYAGRRESLADVEDSIELVIGDITD  60

Query  61   AELVSQLVAESDAVVHFAAESHVDNALDNPEPFLHTNVIGTFTILEAVRRHGVRLHHIST  120
            AELVS+LVAESDAVVHFAAESHVDNAL+ PEPFLHTNV+GTFTILEAVRR+GVRLHHIST
Sbjct  61   AELVSRLVAESDAVVHFAAESHVDNALEGPEPFLHTNVVGTFTILEAVRRYGVRLHHIST  120

Query  121  DEVYGDLELDDRARFTESTPYNPSSPYSATKAGADMLVRAWVRSYGVRATISNCSNNYGP  180
            DEVYGDLELDD  RFTE+TPYNPSSPYSATKA ADMLVRAWVRSYGVRATISNCSNNYGP
Sbjct  121  DEVYGDLELDDPQRFTEATPYNPSSPYSATKAAADMLVRAWVRSYGVRATISNCSNNYGP  180

Query  181  YQHVEKFIPRQITNVLTGRRPKLYGAGANVRDWIHVDDHNSAVRRILDRGRIGRTYLISS  240
            YQHVEKFIPRQITNVLTGRRPKLYG GANVRDWIHVDDHNSAVRRILD+G IGRTYLISS
Sbjct  181  YQHVEKFIPRQITNVLTGRRPKLYGTGANVRDWIHVDDHNSAVRRILDKGEIGRTYLISS  240

Query  241  EGERDNLTVLRTLLRLMDRDPDDFDHVTDRVGHDLRYAIDPSTLYDELCWAPKHTDFEEG  300
            EGERDNLTVLRTLL++M R+PDDFDHVTDRVGHDLRYAIDPSTLYDELCWAPKHTDFEEG
Sbjct  241  EGERDNLTVLRTLLQMMGREPDDFDHVTDRVGHDLRYAIDPSTLYDELCWAPKHTDFEEG  300

Query  301  LRTTIDWYRDNESWWRPLKDATEARYQERGQ  331
            LR TIDWYR NESWWRPLKDA+EARY+ERGQ
Sbjct  301  LRATIDWYRANESWWRPLKDASEARYEERGQ  331


>gi|254819211|ref|ZP_05224212.1| dTDP-glucose 4,6-dehydratase [Mycobacterium intracellulare ATCC 
13950]
Length=331

 Score =  629 bits (1623),  Expect = 2e-178, Method: Compositional matrix adjust.
 Identities = 303/331 (92%), Positives = 317/331 (96%), Gaps = 0/331 (0%)

Query  1    MRLLVTGGAGFIGTNFVHSAVREHPDDAVTVLDALTYAGRRESLADVEDAIRLVQGDITD  60
            MRLLVTGGAGFIG NFVHS VREHP+D+VTVLDALTYAGRRESLA VEDAI LV GDITD
Sbjct  1    MRLLVTGGAGFIGANFVHSTVREHPEDSVTVLDALTYAGRRESLAGVEDAIELVVGDITD  60

Query  61   AELVSQLVAESDAVVHFAAESHVDNALDNPEPFLHTNVIGTFTILEAVRRHGVRLHHIST  120
            AELVS+LVAESDAVVHFAAESHVDNAL+ PEPFLHTNV+GTFTILEAVRR+GVRLHHIST
Sbjct  61   AELVSRLVAESDAVVHFAAESHVDNALEGPEPFLHTNVVGTFTILEAVRRYGVRLHHIST  120

Query  121  DEVYGDLELDDRARFTESTPYNPSSPYSATKAGADMLVRAWVRSYGVRATISNCSNNYGP  180
            DEVYGDLELDD  RFTE+TPYNPSSPYSATKA ADMLVRAWVRSYGVRATISNCSNNYGP
Sbjct  121  DEVYGDLELDDPQRFTEATPYNPSSPYSATKAAADMLVRAWVRSYGVRATISNCSNNYGP  180

Query  181  YQHVEKFIPRQITNVLTGRRPKLYGAGANVRDWIHVDDHNSAVRRILDRGRIGRTYLISS  240
            YQHVEKFIPRQITNVLTGRRPKLYGAGANVRDWIHVDDHNSAVRRIL++G IGRTYLISS
Sbjct  181  YQHVEKFIPRQITNVLTGRRPKLYGAGANVRDWIHVDDHNSAVRRILEKGEIGRTYLISS  240

Query  241  EGERDNLTVLRTLLRLMDRDPDDFDHVTDRVGHDLRYAIDPSTLYDELCWAPKHTDFEEG  300
            EGERDNLTVLRTLL++M R+PDDFDHVTDR GHDLRYAIDPSTLYDELCWAPKHTDFEEG
Sbjct  241  EGERDNLTVLRTLLQMMGREPDDFDHVTDRAGHDLRYAIDPSTLYDELCWAPKHTDFEEG  300

Query  301  LRTTIDWYRDNESWWRPLKDATEARYQERGQ  331
            LR TIDWYR NESWWRPLKDA+EARY+ERGQ
Sbjct  301  LRETIDWYRANESWWRPLKDASEARYEERGQ  331


>gi|296168675|ref|ZP_06850424.1| dTDP-glucose-4,6-dehydratase [Mycobacterium parascrofulaceum 
ATCC BAA-614]
 gi|295896584|gb|EFG76225.1| dTDP-glucose-4,6-dehydratase [Mycobacterium parascrofulaceum 
ATCC BAA-614]
Length=331

 Score =  628 bits (1620),  Expect = 4e-178, Method: Compositional matrix adjust.
 Identities = 303/331 (92%), Positives = 316/331 (96%), Gaps = 0/331 (0%)

Query  1    MRLLVTGGAGFIGTNFVHSAVREHPDDAVTVLDALTYAGRRESLADVEDAIRLVQGDITD  60
            MRLLVTGGAGFIG NFVHS VREHP+D+VTVLDA+TYAGRRESLADVEDAIRLV GDI D
Sbjct  1    MRLLVTGGAGFIGANFVHSTVREHPEDSVTVLDAMTYAGRRESLADVEDAIRLVVGDICD  60

Query  61   AELVSQLVAESDAVVHFAAESHVDNALDNPEPFLHTNVIGTFTILEAVRRHGVRLHHIST  120
            AELVS LVAESDAVVHFAAESHVDNALD+P PFLHTNV+GTFTILEAVRRHG RLHHIST
Sbjct  61   AELVSSLVAESDAVVHFAAESHVDNALDDPAPFLHTNVVGTFTILEAVRRHGGRLHHIST  120

Query  121  DEVYGDLELDDRARFTESTPYNPSSPYSATKAGADMLVRAWVRSYGVRATISNCSNNYGP  180
            DEVYGDLELDD  RFTESTPYNPSSPYSATKAGADMLVRAWVRSYGVRATISNCSNNYGP
Sbjct  121  DEVYGDLELDDPHRFTESTPYNPSSPYSATKAGADMLVRAWVRSYGVRATISNCSNNYGP  180

Query  181  YQHVEKFIPRQITNVLTGRRPKLYGAGANVRDWIHVDDHNSAVRRILDRGRIGRTYLISS  240
            YQHVEKFIPRQITNVLTGRRPKLYG+GANVRDWIHVDDHNSAVRRIL++G IGRTYLISS
Sbjct  181  YQHVEKFIPRQITNVLTGRRPKLYGSGANVRDWIHVDDHNSAVRRILEKGEIGRTYLISS  240

Query  241  EGERDNLTVLRTLLRLMDRDPDDFDHVTDRVGHDLRYAIDPSTLYDELCWAPKHTDFEEG  300
            EGER+NL+VLRTLL++M RDPDDFDHVTDRVGHDLRYAIDPSTLYDELCWAPKHTDFEEG
Sbjct  241  EGERNNLSVLRTLLKMMGRDPDDFDHVTDRVGHDLRYAIDPSTLYDELCWAPKHTDFEEG  300

Query  301  LRTTIDWYRDNESWWRPLKDATEARYQERGQ  331
            L  TIDWYR NESWWRPLKDA EARY+ERGQ
Sbjct  301  LGATIDWYRANESWWRPLKDAAEARYEERGQ  331


>gi|2326950|gb|AAB66648.1| rhamnose biosynthesis protein [Mycobacterium tuberculosis]
Length=329

 Score =  615 bits (1586),  Expect = 3e-174, Method: Compositional matrix adjust.
 Identities = 308/331 (94%), Positives = 310/331 (94%), Gaps = 2/331 (0%)

Query  1    MRLLVTGGAGFIGTNFVHSAVREHPDDAVTVLDALTYAGRRESLADVEDAIRLVQGDITD  60
            MRLLVTGGAGFIGTNFVHSAVREHPDDAVTVLDALTYAGRRESLADVEDAIRLVQGDITD
Sbjct  1    MRLLVTGGAGFIGTNFVHSAVREHPDDAVTVLDALTYAGRRESLADVEDAIRLVQGDITD  60

Query  61   AELVSQLVAESDAVVHFAAESHVDNALDNPEPFLHTNVIGTFTILEAVRRHGVRLHHIST  120
            AELVSQLVAESDAVVHFAAESHVDNALDNPEPFLHTNVIGTFTILEAVRRHGVRLHHIST
Sbjct  61   AELVSQLVAESDAVVHFAAESHVDNALDNPEPFLHTNVIGTFTILEAVRRHGVRLHHIST  120

Query  121  DEVYGDLELDDRARFTESTPYNPSSPYSATKAGADMLVRAWVRSYGVRATISNCSNNYGP  180
            DEVYGDLELDDRARFTESTPYNPSSPYSATKAGADMLVRAWVRS  VRATISNCSNNYGP
Sbjct  121  DEVYGDLELDDRARFTESTPYNPSSPYSATKAGADMLVRAWVRSLCVRATISNCSNNYGP  180

Query  181  YQHVEKFIPRQITNVLTGRRPKLYGAGANVRDWIHVDDHNSAVRRILDRGRIGRTYLISS  240
            YQHVEKFIPRQITN LTG   KLYG G NVRDWIHVDDHNSAVRRILDRGRIG TYLISS
Sbjct  181  YQHVEKFIPRQITNCLTGLL-KLYGDGGNVRDWIHVDDHNSAVRRILDRGRIGETYLISS  239

Query  241  EGERDNLTVLRTLLRLMDRDPDDFDHVTDRVGHDLRYAIDPSTLYDELCWAPKHTDFEEG  300
            EGERDNLTVLR+LLRLMDRDPDDFDHVTDRV HDLRYAIDPS LYDELCWAPKHTDFE  
Sbjct  240  EGERDNLTVLRSLLRLMDRDPDDFDHVTDRVAHDLRYAIDPSRLYDELCWAPKHTDFERA  299

Query  301  LRTTIDWYRDNESWWRPLKDATEARYQERGQ  331
            LRTTIDWYRDNESW   LK A   RYQ+ GQ
Sbjct  300  LRTTIDWYRDNESWLASLKHAG-GRYQDAGQ  329


>gi|240167775|ref|ZP_04746434.1| dTDP-glucose 4,6-dehydratase [Mycobacterium kansasii ATCC 12478]
Length=331

 Score =  594 bits (1531),  Expect = 8e-168, Method: Compositional matrix adjust.
 Identities = 288/331 (88%), Positives = 307/331 (93%), Gaps = 0/331 (0%)

Query  1    MRLLVTGGAGFIGTNFVHSAVREHPDDAVTVLDALTYAGRRESLADVEDAIRLVQGDITD  60
            MRLLVTGGAGFIG NFVHS VRE  +  VTVLDA TYAGRR+SLADV DAI LV+GDITD
Sbjct  1    MRLLVTGGAGFIGANFVHSTVRERHEVQVTVLDAFTYAGRRDSLADVADAITLVEGDITD  60

Query  61   AELVSQLVAESDAVVHFAAESHVDNALDNPEPFLHTNVIGTFTILEAVRRHGVRLHHIST  120
              LVS+LV +SDAVVHFAAE+HVDNALD+PEPFLHTNVIGT+TILEAVRR+GVRLHHIST
Sbjct  61   TGLVSRLVDQSDAVVHFAAETHVDNALDDPEPFLHTNVIGTYTILEAVRRYGVRLHHIST  120

Query  121  DEVYGDLELDDRARFTESTPYNPSSPYSATKAGADMLVRAWVRSYGVRATISNCSNNYGP  180
            DEVYGDL LDD  RFTESTPYNPSSPYSA+KA  DMLVRAWVRSYGVRATISNCSNNYGP
Sbjct  121  DEVYGDLPLDDPQRFTESTPYNPSSPYSASKAAGDMLVRAWVRSYGVRATISNCSNNYGP  180

Query  181  YQHVEKFIPRQITNVLTGRRPKLYGAGANVRDWIHVDDHNSAVRRILDRGRIGRTYLISS  240
            YQHVEKFIPRQITNVLTGRRPKLYG+GANVRDWIHVDDHNSAV RIL++G+IGRTYLIS+
Sbjct  181  YQHVEKFIPRQITNVLTGRRPKLYGSGANVRDWIHVDDHNSAVWRILEKGQIGRTYLISA  240

Query  241  EGERDNLTVLRTLLRLMDRDPDDFDHVTDRVGHDLRYAIDPSTLYDELCWAPKHTDFEEG  300
            EGERDNLTVLRTLLR+M RDPDDFDHVTDRVGHDLRYAIDPS LYDEL WAPKHTD EEG
Sbjct  241  EGERDNLTVLRTLLRMMGRDPDDFDHVTDRVGHDLRYAIDPSPLYDELAWAPKHTDLEEG  300

Query  301  LRTTIDWYRDNESWWRPLKDATEARYQERGQ  331
            LR TIDWYRDNE+WWRPLKDA EARY++RGQ
Sbjct  301  LRATIDWYRDNEAWWRPLKDAAEARYEQRGQ  331


>gi|15828065|ref|NP_302328.1| dTDP-glucose 4,6-dehydratase [Mycobacterium leprae TN]
 gi|221230542|ref|YP_002503958.1| dTDP-glucose 4,6-dehydratase [Mycobacterium leprae Br4923]
 gi|13093619|emb|CAC30919.1| dTDP-glucose 4,6-dehydratase [Mycobacterium leprae]
 gi|219933649|emb|CAR72061.1| dTDP-glucose 4,6-dehydratase [Mycobacterium leprae Br4923]
Length=333

 Score =  585 bits (1507),  Expect = 4e-165, Method: Compositional matrix adjust.
 Identities = 278/331 (84%), Positives = 305/331 (93%), Gaps = 0/331 (0%)

Query  1    MRLLVTGGAGFIGTNFVHSAVREHPDDAVTVLDALTYAGRRESLADVEDAIRLVQGDITD  60
            MRLLVTGGAGFIG NFVH+AVR+HPDD VTVLDA+TYAGR ESLADV+ A+RLVQG+ITD
Sbjct  3    MRLLVTGGAGFIGANFVHNAVRDHPDDTVTVLDAMTYAGRHESLADVDHAVRLVQGNITD  62

Query  61   AELVSQLVAESDAVVHFAAESHVDNALDNPEPFLHTNVIGTFTILEAVRRHGVRLHHIST  120
             +LV +LVAESD VVHFAAE+HVDNALD+PEPFL TNVIGTFTILEAVR H VRLHHIST
Sbjct  63   TKLVFRLVAESDVVVHFAAETHVDNALDDPEPFLRTNVIGTFTILEAVRHHSVRLHHIST  122

Query  121  DEVYGDLELDDRARFTESTPYNPSSPYSATKAGADMLVRAWVRSYGVRATISNCSNNYGP  180
            DEVYGDLELD+  RFTESTPYNPSSPYSATKA  DMLVRAWVRSYGVRATISNCSNNYGP
Sbjct  123  DEVYGDLELDEPTRFTESTPYNPSSPYSATKAAGDMLVRAWVRSYGVRATISNCSNNYGP  182

Query  181  YQHVEKFIPRQITNVLTGRRPKLYGAGANVRDWIHVDDHNSAVRRILDRGRIGRTYLISS  240
            YQHVEKFIPRQITNVLTGRRPKLYG G NVRDWIHVDDHNSAV +IL++G+IGRTYLI +
Sbjct  183  YQHVEKFIPRQITNVLTGRRPKLYGTGVNVRDWIHVDDHNSAVWQILEKGQIGRTYLIGA  242

Query  241  EGERDNLTVLRTLLRLMDRDPDDFDHVTDRVGHDLRYAIDPSTLYDELCWAPKHTDFEEG  300
            E   +NLTVLRTLL++M RDP+DFDHVTDRVGHDLRYAIDP+ LY+ELCWAPKH +F+EG
Sbjct  243  ENGHNNLTVLRTLLQMMGRDPNDFDHVTDRVGHDLRYAIDPTPLYNELCWAPKHANFDEG  302

Query  301  LRTTIDWYRDNESWWRPLKDATEARYQERGQ  331
            LR TIDWYR+NESWWRPLKDA EARY+ERG+
Sbjct  303  LRATIDWYRNNESWWRPLKDAVEARYEERGR  333


>gi|4539118|emb|CAB39839.1| putative dTDP-(glucose or rhamnose)-4,6-dehydratase [Mycobacterium 
leprae]
Length=331

 Score =  585 bits (1507),  Expect = 4e-165, Method: Compositional matrix adjust.
 Identities = 278/331 (84%), Positives = 305/331 (93%), Gaps = 0/331 (0%)

Query  1    MRLLVTGGAGFIGTNFVHSAVREHPDDAVTVLDALTYAGRRESLADVEDAIRLVQGDITD  60
            MRLLVTGGAGFIG NFVH+AVR+HPDD VTVLDA+TYAGR ESLADV+ A+RLVQG+ITD
Sbjct  1    MRLLVTGGAGFIGANFVHNAVRDHPDDTVTVLDAMTYAGRHESLADVDHAVRLVQGNITD  60

Query  61   AELVSQLVAESDAVVHFAAESHVDNALDNPEPFLHTNVIGTFTILEAVRRHGVRLHHIST  120
             +LV +LVAESD VVHFAAE+HVDNALD+PEPFL TNVIGTFTILEAVR H VRLHHIST
Sbjct  61   TKLVFRLVAESDVVVHFAAETHVDNALDDPEPFLRTNVIGTFTILEAVRHHSVRLHHIST  120

Query  121  DEVYGDLELDDRARFTESTPYNPSSPYSATKAGADMLVRAWVRSYGVRATISNCSNNYGP  180
            DEVYGDLELD+  RFTESTPYNPSSPYSATKA  DMLVRAWVRSYGVRATISNCSNNYGP
Sbjct  121  DEVYGDLELDEPTRFTESTPYNPSSPYSATKAAGDMLVRAWVRSYGVRATISNCSNNYGP  180

Query  181  YQHVEKFIPRQITNVLTGRRPKLYGAGANVRDWIHVDDHNSAVRRILDRGRIGRTYLISS  240
            YQHVEKFIPRQITNVLTGRRPKLYG G NVRDWIHVDDHNSAV +IL++G+IGRTYLI +
Sbjct  181  YQHVEKFIPRQITNVLTGRRPKLYGTGVNVRDWIHVDDHNSAVWQILEKGQIGRTYLIGA  240

Query  241  EGERDNLTVLRTLLRLMDRDPDDFDHVTDRVGHDLRYAIDPSTLYDELCWAPKHTDFEEG  300
            E   +NLTVLRTLL++M RDP+DFDHVTDRVGHDLRYAIDP+ LY+ELCWAPKH +F+EG
Sbjct  241  ENGHNNLTVLRTLLQMMGRDPNDFDHVTDRVGHDLRYAIDPTPLYNELCWAPKHANFDEG  300

Query  301  LRTTIDWYRDNESWWRPLKDATEARYQERGQ  331
            LR TIDWYR+NESWWRPLKDA EARY+ERG+
Sbjct  301  LRATIDWYRNNESWWRPLKDAVEARYEERGR  331


>gi|118467903|ref|YP_885894.1| dTDP-glucose 4,6-dehydratase [Mycobacterium smegmatis str. MC2 
155]
 gi|310947298|sp|A0QSK6.1|RMLB_MYCS2 RecName: Full=dTDP-glucose 4,6-dehydratase
 gi|118169190|gb|ABK70086.1| dTDP-glucose 4,6-dehydratase [Mycobacterium smegmatis str. MC2 
155]
Length=331

 Score =  573 bits (1477),  Expect = 1e-161, Method: Compositional matrix adjust.
 Identities = 278/331 (84%), Positives = 297/331 (90%), Gaps = 0/331 (0%)

Query  1    MRLLVTGGAGFIGTNFVHSAVREHPDDAVTVLDALTYAGRRESLADVEDAIRLVQGDITD  60
            MRLLVTGGAGFIG NFVH A+RE    ++TVLDALTYAG RESLA V D IRLVQGDITD
Sbjct  1    MRLLVTGGAGFIGANFVHLALREARTSSITVLDALTYAGSRESLAPVADRIRLVQGDITD  60

Query  61   AELVSQLVAESDAVVHFAAESHVDNALDNPEPFLHTNVIGTFTILEAVRRHGVRLHHIST  120
            A LV  LVAESDAVVHFAAE+HVDNAL +PEPFLH+NV+GT+TILEAVRRH VRLHH+ST
Sbjct  61   AALVGDLVAESDAVVHFAAETHVDNALADPEPFLHSNVVGTYTILEAVRRHNVRLHHVST  120

Query  121  DEVYGDLELDDRARFTESTPYNPSSPYSATKAGADMLVRAWVRSYGVRATISNCSNNYGP  180
            DEVYGDLELD+ ARF E+TPYNPSSPYS+TKA AD+LVRAWVRSYGVRATISNCSNNYGP
Sbjct  121  DEVYGDLELDNPARFNETTPYNPSSPYSSTKAAADLLVRAWVRSYGVRATISNCSNNYGP  180

Query  181  YQHVEKFIPRQITNVLTGRRPKLYGAGANVRDWIHVDDHNSAVRRILDRGRIGRTYLISS  240
            YQHVEKFIPRQITNVLTGRRPKLYGAGANVRDWIHVDDHNSAV RIL  G IGRTYLI +
Sbjct  181  YQHVEKFIPRQITNVLTGRRPKLYGAGANVRDWIHVDDHNSAVWRILTDGTIGRTYLIGA  240

Query  241  EGERDNLTVLRTLLRLMDRDPDDFDHVTDRVGHDLRYAIDPSTLYDELCWAPKHTDFEEG  300
            E ER+NLTV+RT+L+LM RDPDDFDHVTDR GHDLRYAIDPSTL DEL WAPKHTDFE G
Sbjct  241  ECERNNLTVMRTILKLMGRDPDDFDHVTDRAGHDLRYAIDPSTLQDELGWAPKHTDFEAG  300

Query  301  LRTTIDWYRDNESWWRPLKDATEARYQERGQ  331
            L  TIDWYR NESWWRPLKD  EA+YQERGQ
Sbjct  301  LTDTIDWYRANESWWRPLKDTVEAKYQERGQ  331


>gi|108798039|ref|YP_638236.1| dTDP-glucose 4,6-dehydratase [Mycobacterium sp. MCS]
 gi|119867134|ref|YP_937086.1| dTDP-glucose 4,6-dehydratase [Mycobacterium sp. KMS]
 gi|108768458|gb|ABG07180.1| dTDP-glucose 4,6-dehydratase [Mycobacterium sp. MCS]
 gi|119693223|gb|ABL90296.1| dTDP-glucose 4,6-dehydratase [Mycobacterium sp. KMS]
Length=335

 Score =  561 bits (1446),  Expect = 5e-158, Method: Compositional matrix adjust.
 Identities = 272/335 (82%), Positives = 294/335 (88%), Gaps = 4/335 (1%)

Query  1    MRLLVTGGAGFIGTNFVHSAVREHPDDAVTVLDALTYAGRRESLADVEDAIRLVQGDITD  60
            MRLLVTGGAGFIG NFVH+ VREHPD AVTVLDA TYAG RESLA V D IRLV+GD+ D
Sbjct  1    MRLLVTGGAGFIGANFVHATVREHPDYAVTVLDAFTYAGSRESLAPVADRIRLVEGDVAD  60

Query  61   AELVSQLVAE----SDAVVHFAAESHVDNALDNPEPFLHTNVIGTFTILEAVRRHGVRLH  116
            A LV  LV +    +DAVVHFAAE+HVDNAL +P PF+ TNV+GT+T+LEAVRR GVRLH
Sbjct  61   AALVGGLVDDLDPATDAVVHFAAETHVDNALADPGPFVQTNVVGTYTVLEAVRRAGVRLH  120

Query  117  HISTDEVYGDLELDDRARFTESTPYNPSSPYSATKAGADMLVRAWVRSYGVRATISNCSN  176
            H+STDEVYGDL LDD  RFTESTPYNPSSPYS+TKA AD+LVRAWVRSYGVRATISNCSN
Sbjct  121  HVSTDEVYGDLALDDPQRFTESTPYNPSSPYSSTKAAADLLVRAWVRSYGVRATISNCSN  180

Query  177  NYGPYQHVEKFIPRQITNVLTGRRPKLYGAGANVRDWIHVDDHNSAVRRILDRGRIGRTY  236
            NYGPYQHVEKFIPRQITN+LTGRRPKLYG GANVRDWIHVDDHNSAV RIL  G +GRTY
Sbjct  181  NYGPYQHVEKFIPRQITNILTGRRPKLYGTGANVRDWIHVDDHNSAVWRILRDGVVGRTY  240

Query  237  LISSEGERDNLTVLRTLLRLMDRDPDDFDHVTDRVGHDLRYAIDPSTLYDELCWAPKHTD  296
            LI +EGERDNL+VLRTLLR+MDRDPDDFDHVTDR GHDLRYAIDPS LYDEL W P H D
Sbjct  241  LIGAEGERDNLSVLRTLLRIMDRDPDDFDHVTDRAGHDLRYAIDPSVLYDELGWKPAHLD  300

Query  297  FEEGLRTTIDWYRDNESWWRPLKDATEARYQERGQ  331
            FEEGLR T+ WYRDNE+WWRPLKDA EA Y+ERGQ
Sbjct  301  FEEGLRATVQWYRDNEAWWRPLKDAAEAAYEERGQ  335


>gi|126433700|ref|YP_001069391.1| dTDP-glucose 4,6-dehydratase [Mycobacterium sp. JLS]
 gi|126233500|gb|ABN96900.1| dTDP-glucose 4,6-dehydratase [Mycobacterium sp. JLS]
Length=335

 Score =  559 bits (1440),  Expect = 2e-157, Method: Compositional matrix adjust.
 Identities = 271/335 (81%), Positives = 294/335 (88%), Gaps = 4/335 (1%)

Query  1    MRLLVTGGAGFIGTNFVHSAVREHPDDAVTVLDALTYAGRRESLADVEDAIRLVQGDITD  60
            MRLLVTGGAGFIG NFVH+ VREHPD AVTVLDA TYAG RESLA V D IRLV+GD+ D
Sbjct  1    MRLLVTGGAGFIGANFVHATVREHPDYAVTVLDAFTYAGSRESLAPVADRIRLVEGDVAD  60

Query  61   AELVSQLVAE----SDAVVHFAAESHVDNALDNPEPFLHTNVIGTFTILEAVRRHGVRLH  116
            A LV  LV +    +DAVVHFAAE+HVDNAL +P PF+ TNV+GT+T+LEAVRR GVRLH
Sbjct  61   AGLVGGLVDDLDPATDAVVHFAAETHVDNALADPGPFVQTNVVGTYTVLEAVRRAGVRLH  120

Query  117  HISTDEVYGDLELDDRARFTESTPYNPSSPYSATKAGADMLVRAWVRSYGVRATISNCSN  176
            H+STDEVYGDL LDD  RFTESTPYNPSSPYS+TKA AD+LVRAWVRSYGVRATISNCSN
Sbjct  121  HVSTDEVYGDLALDDPRRFTESTPYNPSSPYSSTKAAADLLVRAWVRSYGVRATISNCSN  180

Query  177  NYGPYQHVEKFIPRQITNVLTGRRPKLYGAGANVRDWIHVDDHNSAVRRILDRGRIGRTY  236
            NYGPYQHVEKFIPRQITN+LTGRRPKLYG GANVRDWIHVDDHNSAV RIL  G +GRTY
Sbjct  181  NYGPYQHVEKFIPRQITNILTGRRPKLYGTGANVRDWIHVDDHNSAVWRILRDGVVGRTY  240

Query  237  LISSEGERDNLTVLRTLLRLMDRDPDDFDHVTDRVGHDLRYAIDPSTLYDELCWAPKHTD  296
            LI +EGERDNL+VLRTLLR+MDRDPDDFDHVTDR GHDLRYAIDPS LYDEL W P H D
Sbjct  241  LIGAEGERDNLSVLRTLLRIMDRDPDDFDHVTDRAGHDLRYAIDPSVLYDELGWKPAHLD  300

Query  297  FEEGLRTTIDWYRDNESWWRPLKDATEARYQERGQ  331
            FEEGLR T+ WYRDNE+WWRPLKDA E+ Y+ERGQ
Sbjct  301  FEEGLRATVQWYRDNEAWWRPLKDAAESAYEERGQ  335


>gi|120402376|ref|YP_952205.1| dTDP-glucose 4,6-dehydratase [Mycobacterium vanbaalenii PYR-1]
 gi|119955194|gb|ABM12199.1| dTDP-glucose 4,6-dehydratase [Mycobacterium vanbaalenii PYR-1]
Length=335

 Score =  539 bits (1388),  Expect = 2e-151, Method: Compositional matrix adjust.
 Identities = 264/333 (80%), Positives = 291/333 (88%), Gaps = 4/333 (1%)

Query  1    MRLLVTGGAGFIGTNFVHSAVREHPDDAVTVLDALTYAGRRESLADVEDAIRLVQGDITD  60
            MRLLVTGGAGFIG NFV + V++ PD  VTVLD+LTYAG RESL  V+  IRLV+GDITD
Sbjct  1    MRLLVTGGAGFIGANFVRTTVQQRPDVQVTVLDSLTYAGSRESLRGVDSQIRLVEGDITD  60

Query  61   AELVSQLVAESDAVVHFAAESHVDNALDNPEPFLHTNVIGTFTILEAVRRHGV----RLH  116
            AELV +LVA+SDAVVHFAAE+HVDNAL +PEPF+H+NV+GTFT+LEAVR   V    RLH
Sbjct  61   AELVGKLVADSDAVVHFAAETHVDNALADPEPFVHSNVLGTFTVLEAVRHASVTKPVRLH  120

Query  117  HISTDEVYGDLELDDRARFTESTPYNPSSPYSATKAGADMLVRAWVRSYGVRATISNCSN  176
            HISTDEVYGDLELDD ARFT++TPYNPSSPYS+TKA ADMLVRAWVRSY V ATISNCSN
Sbjct  121  HISTDEVYGDLELDDPARFTDATPYNPSSPYSSTKAAADMLVRAWVRSYRVAATISNCSN  180

Query  177  NYGPYQHVEKFIPRQITNVLTGRRPKLYGAGANVRDWIHVDDHNSAVRRILDRGRIGRTY  236
            NYGPYQHVEKFIPRQITNVLTGRRP+LYG GANVRDWIHVDDHNSAV RIL  G +GRTY
Sbjct  181  NYGPYQHVEKFIPRQITNVLTGRRPELYGTGANVRDWIHVDDHNSAVWRILHDGTVGRTY  240

Query  237  LISSEGERDNLTVLRTLLRLMDRDPDDFDHVTDRVGHDLRYAIDPSTLYDELCWAPKHTD  296
            LI ++GERDNL+V+RT+LRLM R P+DFDHVTDRVGHDLRYAIDP+ L DEL W P+HTD
Sbjct  241  LIGADGERDNLSVMRTILRLMGRSPEDFDHVTDRVGHDLRYAIDPTPLRDELGWRPEHTD  300

Query  297  FEEGLRTTIDWYRDNESWWRPLKDATEARYQER  329
            FE GLR TIDWYRDNESWW PLKDA EA YQ R
Sbjct  301  FESGLRDTIDWYRDNESWWGPLKDAVEATYQRR  333


>gi|333991927|ref|YP_004524541.1| dTDP-glucose-46-dehydratase RmlB [Mycobacterium sp. JDM601]
 gi|333487895|gb|AEF37287.1| dTDP-glucose-46-dehydratase RmlB [Mycobacterium sp. JDM601]
Length=331

 Score =  530 bits (1366),  Expect = 9e-149, Method: Compositional matrix adjust.
 Identities = 256/331 (78%), Positives = 284/331 (86%), Gaps = 0/331 (0%)

Query  1    MRLLVTGGAGFIGTNFVHSAVREHPDDAVTVLDALTYAGRRESLADVEDAIRLVQGDITD  60
            MRLLVTGGAGFIG NFVHS + + P   +TVLDALTYAG RESL D+   IRLV+GDITD
Sbjct  1    MRLLVTGGAGFIGANFVHSTLAQRPGAEITVLDALTYAGSRESLGDITADIRLVEGDITD  60

Query  61   AELVSQLVAESDAVVHFAAESHVDNALDNPEPFLHTNVIGTFTILEAVRRHGVRLHHIST  120
            A LVSQLVAESDAVVHFAAE+HVDNAL +PEPFL +NV+GTFT+LEAVR H VRLHH+ST
Sbjct  61   ATLVSQLVAESDAVVHFAAETHVDNALADPEPFLRSNVVGTFTVLEAVRAHRVRLHHVST  120

Query  121  DEVYGDLELDDRARFTESTPYNPSSPYSATKAGADMLVRAWVRSYGVRATISNCSNNYGP  180
            DEVYG+L LDD  RFTE+TPY+PSSPYS+TKA AD+LVR+WVRSYG  ATISNCSNNYGP
Sbjct  121  DEVYGELALDDPRRFTETTPYHPSSPYSSTKAAADLLVRSWVRSYGTHATISNCSNNYGP  180

Query  181  YQHVEKFIPRQITNVLTGRRPKLYGAGANVRDWIHVDDHNSAVRRILDRGRIGRTYLISS  240
            YQHVEKFIPRQITN+LTGRR KLYG+GANVRDWIHVDDHNSAV  I+  G  GRTYLI +
Sbjct  181  YQHVEKFIPRQITNLLTGRRAKLYGSGANVRDWIHVDDHNSAVWAIMTGGHPGRTYLIGA  240

Query  241  EGERDNLTVLRTLLRLMDRDPDDFDHVTDRVGHDLRYAIDPSTLYDELCWAPKHTDFEEG  300
            +GERDN +VL+ +LRLMD DPDDFDHV DR GHDLRYAIDPS L DEL W P+HTDFE G
Sbjct  241  DGERDNRSVLQAILRLMDHDPDDFDHVADRPGHDLRYAIDPSALRDELGWKPEHTDFEAG  300

Query  301  LRTTIDWYRDNESWWRPLKDATEARYQERGQ  331
            LR TI+WYR NESWW PLKDA EARY E G+
Sbjct  301  LRATIEWYRANESWWAPLKDAAEARYAELGR  331


>gi|145225583|ref|YP_001136261.1| dTDP-glucose 4,6-dehydratase [Mycobacterium gilvum PYR-GCK]
 gi|145218069|gb|ABP47473.1| dTDP-glucose 4,6-dehydratase [Mycobacterium gilvum PYR-GCK]
Length=335

 Score =  528 bits (1361),  Expect = 4e-148, Method: Compositional matrix adjust.
 Identities = 256/335 (77%), Positives = 286/335 (86%), Gaps = 4/335 (1%)

Query  1    MRLLVTGGAGFIGTNFVHSAVREHPDDAVTVLDALTYAGRRESLADVEDAIRLVQGDITD  60
            MRLLVTGGAGFIG NFV + VR+ PD  VTVLD+LTYAG RESLA V+  IRLVQGDITD
Sbjct  1    MRLLVTGGAGFIGANFVLATVRDRPDVRVTVLDSLTYAGSRESLAGVDTQIRLVQGDITD  60

Query  61   AELVSQLVAESDAVVHFAAESHVDNALDNPEPFLHTNVIGTFTILEAVRRHG----VRLH  116
            A+LV +LV ESDAVVHFAAE+HVDNAL +PEPF+ +N++GTFTILEAVR       VRLH
Sbjct  61   ADLVGRLVGESDAVVHFAAETHVDNALADPEPFVRSNIVGTFTILEAVRHAAASRPVRLH  120

Query  117  HISTDEVYGDLELDDRARFTESTPYNPSSPYSATKAGADMLVRAWVRSYGVRATISNCSN  176
            H+STDEVYGDLEL D A+FTESTPYNPSSPYS+TKA +DMLVRAWVRSY + AT+SNCSN
Sbjct  121  HVSTDEVYGDLELGDPAKFTESTPYNPSSPYSSTKAASDMLVRAWVRSYRLTATLSNCSN  180

Query  177  NYGPYQHVEKFIPRQITNVLTGRRPKLYGAGANVRDWIHVDDHNSAVRRILDRGRIGRTY  236
            NYGP+QHVEKFIPRQITN+LTGRRPKLYG GANVRDWIHV+DHNSAV +IL  G +GRTY
Sbjct  181  NYGPFQHVEKFIPRQITNILTGRRPKLYGTGANVRDWIHVEDHNSAVWKILTHGAVGRTY  240

Query  237  LISSEGERDNLTVLRTLLRLMDRDPDDFDHVTDRVGHDLRYAIDPSTLYDELCWAPKHTD  296
            LI ++GE DNLTV+RT+LRLMDR PDDFDHVTDR GHDLRYAID + L DEL W P H+D
Sbjct  241  LIGADGECDNLTVMRTILRLMDRSPDDFDHVTDRAGHDLRYAIDATALRDELGWRPAHSD  300

Query  297  FEEGLRTTIDWYRDNESWWRPLKDATEARYQERGQ  331
            FE GLR TIDWY  NESWW P+KDA EA YQ RGQ
Sbjct  301  FEAGLRDTIDWYSANESWWGPIKDAVEAGYQSRGQ  335


>gi|315445936|ref|YP_004078815.1| dTDP-glucose 4,6-dehydratase [Mycobacterium sp. Spyr1]
 gi|315264239|gb|ADU00981.1| dTDP-glucose 4,6-dehydratase [Mycobacterium sp. Spyr1]
Length=335

 Score =  525 bits (1352),  Expect = 4e-147, Method: Compositional matrix adjust.
 Identities = 256/335 (77%), Positives = 285/335 (86%), Gaps = 4/335 (1%)

Query  1    MRLLVTGGAGFIGTNFVHSAVREHPDDAVTVLDALTYAGRRESLADVEDAIRLVQGDITD  60
            MRLLVTGGAGFIG NFV + VR+ PD  VTVLD+LTYAG RESLA V+  IRLVQGDITD
Sbjct  1    MRLLVTGGAGFIGANFVLATVRDRPDVRVTVLDSLTYAGSRESLAGVDTQIRLVQGDITD  60

Query  61   AELVSQLVAESDAVVHFAAESHVDNALDNPEPFLHTNVIGTFTILEAVRR----HGVRLH  116
            A+LV +LV ESDAVVHFAAE+HVDNAL +PEPF+ +N++GTFTILEAVR       VRLH
Sbjct  61   ADLVGRLVGESDAVVHFAAETHVDNALADPEPFVRSNIVGTFTILEAVRHATASRPVRLH  120

Query  117  HISTDEVYGDLELDDRARFTESTPYNPSSPYSATKAGADMLVRAWVRSYGVRATISNCSN  176
            H+STDEVYGDLEL D A+FTESTPYNPSSPYS+TKA +DMLVRAWVRSY + AT+SNCSN
Sbjct  121  HVSTDEVYGDLELGDPAKFTESTPYNPSSPYSSTKAASDMLVRAWVRSYRLTATLSNCSN  180

Query  177  NYGPYQHVEKFIPRQITNVLTGRRPKLYGAGANVRDWIHVDDHNSAVRRILDRGRIGRTY  236
            NYGP+QHVEKFIPRQITN+LTGRRPKLYG GANVRDWIHV+DHNSAV +IL  G +GRTY
Sbjct  181  NYGPFQHVEKFIPRQITNILTGRRPKLYGTGANVRDWIHVEDHNSAVWKILTHGAVGRTY  240

Query  237  LISSEGERDNLTVLRTLLRLMDRDPDDFDHVTDRVGHDLRYAIDPSTLYDELCWAPKHTD  296
            LI ++GE DNLTV+RT+LRLMDR PDDFDHVTDR GHDLRYAID + L DEL W P H D
Sbjct  241  LIGADGECDNLTVMRTILRLMDRSPDDFDHVTDRAGHDLRYAIDATPLRDELGWRPAHRD  300

Query  297  FEEGLRTTIDWYRDNESWWRPLKDATEARYQERGQ  331
            FE GLR TIDWYR N SWW P+KDA EA YQ RGQ
Sbjct  301  FEAGLRDTIDWYRHNRSWWGPIKDAVEAAYQSRGQ  335


>gi|169630859|ref|YP_001704508.1| dTDP-glucose 4,6-dehydratase RmlB [Mycobacterium abscessus ATCC 
19977]
 gi|169242826|emb|CAM63854.1| DTDP-glucose 4,6-dehydratase RmlB [Mycobacterium abscessus]
Length=331

 Score =  525 bits (1351),  Expect = 5e-147, Method: Compositional matrix adjust.
 Identities = 248/331 (75%), Positives = 283/331 (86%), Gaps = 0/331 (0%)

Query  1    MRLLVTGGAGFIGTNFVHSAVREHPDDAVTVLDALTYAGRRESLADVEDAIRLVQGDITD  60
            MR+LVTGGAGFIG NFVH+ VRE PD +VTVLDALTYAG  ESLA V  A++LVQGDI D
Sbjct  1    MRILVTGGAGFIGANFVHATVRERPDVSVTVLDALTYAGSSESLAPVAAAVQLVQGDICD  60

Query  61   AELVSQLVAESDAVVHFAAESHVDNALDNPEPFLHTNVIGTFTILEAVRRHGVRLHHIST  120
             + V +LVA+SD VVHFAAE+H DN+L +P PFL +N+IGT+T+LEAVRRH VRLHHIST
Sbjct  61   PDTVERLVADSDVVVHFAAETHNDNSLADPSPFLRSNIIGTYTLLEAVRRHQVRLHHIST  120

Query  121  DEVYGDLELDDRARFTESTPYNPSSPYSATKAGADMLVRAWVRSYGVRATISNCSNNYGP  180
            DEV+GDLELDD  RFTE+TPYNPSSPYSATKA AD+LVRAW+RS+G+ ATISNCSNNYGP
Sbjct  121  DEVFGDLELDDPNRFTETTPYNPSSPYSATKASADLLVRAWIRSFGISATISNCSNNYGP  180

Query  181  YQHVEKFIPRQITNVLTGRRPKLYGAGANVRDWIHVDDHNSAVRRILDRGRIGRTYLISS  240
            YQHVEKFIPRQITN+LTGRRP+LYGAGANVRDWIHVDDHNSAV RI++ G IGRTYLI +
Sbjct  181  YQHVEKFIPRQITNILTGRRPRLYGAGANVRDWIHVDDHNSAVWRIIEAGTIGRTYLIGA  240

Query  241  EGERDNLTVLRTLLRLMDRDPDDFDHVTDRVGHDLRYAIDPSTLYDELCWAPKHTDFEEG  300
            +GERDNL+VL T+L LM +  DDFDHVTDR GHDLRYAIDP+ L DEL W P H+DF  G
Sbjct  241  DGERDNLSVLHTILELMGKSSDDFDHVTDRAGHDLRYAIDPTPLRDELGWKPTHSDFTGG  300

Query  301  LRTTIDWYRDNESWWRPLKDATEARYQERGQ  331
            L  TIDWYR NE WWRP+KD  E++Y  RGQ
Sbjct  301  LAATIDWYRRNEEWWRPIKDNVESQYAARGQ  331


>gi|325673207|ref|ZP_08152900.1| dTDP-glucose-4,6-dehydratase [Rhodococcus equi ATCC 33707]
 gi|325556042|gb|EGD25711.1| dTDP-glucose-4,6-dehydratase [Rhodococcus equi ATCC 33707]
Length=331

 Score =  508 bits (1308),  Expect = 5e-142, Method: Compositional matrix adjust.
 Identities = 242/330 (74%), Positives = 280/330 (85%), Gaps = 0/330 (0%)

Query  1    MRLLVTGGAGFIGTNFVHSAVREHPDDAVTVLDALTYAGRRESLADVEDAIRLVQGDITD  60
            MR+LVTGGAGFIG NFVH+ +RE P   VTVLDALTYAG R++L  V+ +IR V+GDI D
Sbjct  1    MRVLVTGGAGFIGANFVHTTLRERPGVEVTVLDALTYAGSRDTLRSVDSSIRFVEGDIAD  60

Query  61   AELVSQLVAESDAVVHFAAESHVDNALDNPEPFLHTNVIGTFTILEAVRRHGVRLHHIST  120
            A +V  LVAESD VVHFAAESH DN+L +P PF+ TNVIGT+T+LEAVR HGVR HH+ST
Sbjct  61   ATVVGALVAESDFVVHFAAESHNDNSLSDPWPFVRTNVIGTYTLLEAVREHGVRYHHVST  120

Query  121  DEVYGDLELDDRARFTESTPYNPSSPYSATKAGADMLVRAWVRSYGVRATISNCSNNYGP  180
            DEVYGDL LDD  +FTE +PYNPSSPYS+TKA +DMLVRAWVRS+GVRAT+SNCSNNYGP
Sbjct  121  DEVYGDLALDDPGKFTEHSPYNPSSPYSSTKAASDMLVRAWVRSFGVRATLSNCSNNYGP  180

Query  181  YQHVEKFIPRQITNVLTGRRPKLYGAGANVRDWIHVDDHNSAVRRILDRGRIGRTYLISS  240
            YQH+EKFIPRQITN+LTG RPKLYGAG NVRDWIHVDDHNSAV +IL+ G +GRTYLI +
Sbjct  181  YQHIEKFIPRQITNILTGVRPKLYGAGLNVRDWIHVDDHNSAVWKILEDGELGRTYLIGA  240

Query  241  EGERDNLTVLRTLLRLMDRDPDDFDHVTDRVGHDLRYAIDPSTLYDELCWAPKHTDFEEG  300
            +GE DNLTV+RT+L LM RDPD F+HVTDR GHDLRYAID STL DEL W+P++TDF EG
Sbjct  241  DGEVDNLTVVRTILELMGRDPDGFEHVTDRPGHDLRYAIDASTLRDELGWSPRYTDFREG  300

Query  301  LRTTIDWYRDNESWWRPLKDATEARYQERG  330
            L  TIDWY+DN +WW   KDA EARY+ +G
Sbjct  301  LAATIDWYQDNRAWWEREKDAVEARYRAQG  330


>gi|269957347|ref|YP_003327136.1| dTDP-glucose 4,6-dehydratase [Xylanimonas cellulosilytica DSM 
15894]
 gi|269306028|gb|ACZ31578.1| dTDP-glucose 4,6-dehydratase [Xylanimonas cellulosilytica DSM 
15894]
Length=331

 Score =  506 bits (1302),  Expect = 3e-141, Method: Compositional matrix adjust.
 Identities = 237/331 (72%), Positives = 278/331 (84%), Gaps = 0/331 (0%)

Query  1    MRLLVTGGAGFIGTNFVHSAVREHPDDAVTVLDALTYAGRRESLADVEDAIRLVQGDITD  60
            M++LVTGGAGFIG NFVH  VRE PD  VTVLDALTYAG R SLA V D I LV+G ITD
Sbjct  1    MQVLVTGGAGFIGANFVHQTVRERPDVQVTVLDALTYAGDRASLAPVADKITLVEGSITD  60

Query  61   AELVSQLVAESDAVVHFAAESHVDNALDNPEPFLHTNVIGTFTILEAVRRHGVRLHHIST  120
            A LV +LVA SD VVHFAAESH DN+L++P PF+ TNV+GTFT+LEAVR+HGVR HHIST
Sbjct  61   AALVDRLVAASDLVVHFAAESHNDNSLNDPSPFVQTNVVGTFTLLEAVRKHGVRFHHIST  120

Query  121  DEVYGDLELDDRARFTESTPYNPSSPYSATKAGADMLVRAWVRSYGVRATISNCSNNYGP  180
            DEVYGDLELDD A+FT  TPYNPSSPYS+TKAG+D+LVRAWVRS+GV+ATISNCSNNYGP
Sbjct  121  DEVYGDLELDDPAKFTPETPYNPSSPYSSTKAGSDLLVRAWVRSFGVQATISNCSNNYGP  180

Query  181  YQHVEKFIPRQITNVLTGRRPKLYGAGANVRDWIHVDDHNSAVRRILDRGRIGRTYLISS  240
            YQH+EKFIPRQ+TN++ G RP+LYGAG NVRDWIHV+DHNSAV  I+DRG+IG TYLI +
Sbjct  181  YQHIEKFIPRQVTNLIDGIRPRLYGAGQNVRDWIHVEDHNSAVWAIIDRGQIGETYLIGA  240

Query  241  EGERDNLTVLRTLLRLMDRDPDDFDHVTDRVGHDLRYAIDPSTLYDELCWAPKHTDFEEG  300
            +GE++NL V++TLL +  R  DDFDHV DR GHDLRYAID S L +EL W P++TDF  G
Sbjct  241  DGEKNNLEVVQTLLEIFGRPADDFDHVNDRPGHDLRYAIDASRLRNELGWTPQYTDFRSG  300

Query  301  LRTTIDWYRDNESWWRPLKDATEARYQERGQ  331
            L+ T++WY+ NESWWRP K A EA+Y  +GQ
Sbjct  301  LQATVEWYQANESWWRPAKAAVEAKYAAQGQ  331


>gi|334337869|ref|YP_004543021.1| dTDP-glucose 4,6-dehydratase [Isoptericola variabilis 225]
 gi|334108237|gb|AEG45127.1| dTDP-glucose 4,6-dehydratase [Isoptericola variabilis 225]
Length=331

 Score =  501 bits (1291),  Expect = 5e-140, Method: Compositional matrix adjust.
 Identities = 237/331 (72%), Positives = 277/331 (84%), Gaps = 0/331 (0%)

Query  1    MRLLVTGGAGFIGTNFVHSAVREHPDDAVTVLDALTYAGRRESLADVEDAIRLVQGDITD  60
            MRLLVTGGAGFIG+NFV   VRE PD  VTVLDALTYAG R SLA V D + LV+G ITD
Sbjct  1    MRLLVTGGAGFIGSNFVQQTVRERPDVRVTVLDALTYAGDRSSLAPVADKVELVEGSITD  60

Query  61   AELVSQLVAESDAVVHFAAESHVDNALDNPEPFLHTNVIGTFTILEAVRRHGVRLHHIST  120
            AELV +LV +SD VVHFAAESH DN+LD+P PF+ TN++GT+T+LEAVR+H VR HHIST
Sbjct  61   AELVDRLVGDSDLVVHFAAESHNDNSLDDPSPFVQTNLVGTYTLLEAVRKHQVRFHHIST  120

Query  121  DEVYGDLELDDRARFTESTPYNPSSPYSATKAGADMLVRAWVRSYGVRATISNCSNNYGP  180
            DEVYGDLELDD A+FT +TPYNPSSPYS+TKAG+D+LVRAWVRS+GV+ATISNCSNNYGP
Sbjct  121  DEVYGDLELDDPAKFTPTTPYNPSSPYSSTKAGSDLLVRAWVRSFGVQATISNCSNNYGP  180

Query  181  YQHVEKFIPRQITNVLTGRRPKLYGAGANVRDWIHVDDHNSAVRRILDRGRIGRTYLISS  240
            YQHVEKFIPRQITN++ G RP+LYGAG NVRDWIHV+DHN+AV  I++RGRIG TYLI +
Sbjct  181  YQHVEKFIPRQITNLIDGIRPRLYGAGLNVRDWIHVEDHNTAVWAIVERGRIGETYLIGA  240

Query  241  EGERDNLTVLRTLLRLMDRDPDDFDHVTDRVGHDLRYAIDPSTLYDELCWAPKHTDFEEG  300
            +GE+ NL V++TLL +  R  DDFDHV DR GHD+RYAID S L +EL W P++TDF EG
Sbjct  241  DGEKSNLEVVQTLLEIFGRPADDFDHVNDRPGHDMRYAIDASKLREELGWTPRYTDFREG  300

Query  301  LRTTIDWYRDNESWWRPLKDATEARYQERGQ  331
            L+ T+DWYR NE WWRP K A EA+Y   GQ
Sbjct  301  LQATVDWYRANEDWWRPHKAAVEAKYALSGQ  331


>gi|269794222|ref|YP_003313677.1| dTDP-glucose 4,6-dehydratase [Sanguibacter keddieii DSM 10542]
 gi|269096407|gb|ACZ20843.1| dTDP-glucose 4,6-dehydratase [Sanguibacter keddieii DSM 10542]
Length=331

 Score =  494 bits (1273),  Expect = 6e-138, Method: Compositional matrix adjust.
 Identities = 234/331 (71%), Positives = 275/331 (84%), Gaps = 0/331 (0%)

Query  1    MRLLVTGGAGFIGTNFVHSAVREHPDDAVTVLDALTYAGRRESLADVEDAIRLVQGDITD  60
            MRLLVTGGAGFIG+NFVH+ VR+ PD  VTVLDALTYAG   SLA V D + LVQGDITD
Sbjct  1    MRLLVTGGAGFIGSNFVHTTVRDRPDVEVTVLDALTYAGDATSLAPVADRVTLVQGDITD  60

Query  61   AELVSQLVAESDAVVHFAAESHVDNALDNPEPFLHTNVIGTFTILEAVRRHGVRLHHIST  120
              LV +LV ESD VVHFAAESH DN+L +P PF+ TN+IGT+T+LEAVR+HGVR HHIST
Sbjct  61   GALVDRLVGESDLVVHFAAESHNDNSLHDPWPFVQTNLIGTYTLLEAVRKHGVRYHHIST  120

Query  121  DEVYGDLELDDRARFTESTPYNPSSPYSATKAGADMLVRAWVRSYGVRATISNCSNNYGP  180
            DEVYGDLELDD A+FT  TPYNPSSPYS+TKAG+D+LVRAW RS+GV+ATISNCSNNYGP
Sbjct  121  DEVYGDLELDDPAKFTADTPYNPSSPYSSTKAGSDLLVRAWARSFGVQATISNCSNNYGP  180

Query  181  YQHVEKFIPRQITNVLTGRRPKLYGAGANVRDWIHVDDHNSAVRRILDRGRIGRTYLISS  240
            YQH+EKFIPRQ+TN++ G RP+LYGAG NVRDWIHV+DHN+AV  I+DRG+IG TYLI +
Sbjct  181  YQHIEKFIPRQVTNLIDGVRPRLYGAGENVRDWIHVEDHNTAVWAIIDRGQIGETYLIGA  240

Query  241  EGERDNLTVLRTLLRLMDRDPDDFDHVTDRVGHDLRYAIDPSTLYDELCWAPKHTDFEEG  300
            +GE++NL V++TLL +  R  DDFDHVTDR GHD+RYAID + L  EL W P  TDF  G
Sbjct  241  DGEKNNLEVVQTLLEVFGRPTDDFDHVTDRAGHDMRYAIDATRLRTELGWEPTFTDFGAG  300

Query  301  LRTTIDWYRDNESWWRPLKDATEARYQERGQ  331
            LR T++WYR NE+WWRP K ATEA+Y + G 
Sbjct  301  LRATVEWYRANEAWWRPAKAATEAKYAQAGH  331


>gi|323357014|ref|YP_004223410.1| dTDP-D-glucose 4,6-dehydratase [Microbacterium testaceum StLB037]
 gi|323273385|dbj|BAJ73530.1| dTDP-D-glucose 4,6-dehydratase [Microbacterium testaceum StLB037]
Length=332

 Score =  483 bits (1244),  Expect = 1e-134, Method: Compositional matrix adjust.
 Identities = 239/331 (73%), Positives = 269/331 (82%), Gaps = 2/331 (0%)

Query  2    RLLVTGGAGFIGTNFVHSAVREHPDDAVTVLDALTYAGRRESLADV-EDAIRLVQGDITD  60
            RLLVTGGAGFIG+NFVH  V  H +  VTVLD LTYAG R SLA + ED +RLV GDI D
Sbjct  3    RLLVTGGAGFIGSNFVHHVV-AHTEHTVTVLDKLTYAGNRASLAGLPEDRVRLVVGDIAD  61

Query  61   AELVSQLVAESDAVVHFAAESHVDNALDNPEPFLHTNVIGTFTILEAVRRHGVRLHHIST  120
            A +V  LVAE+DAVVH+AAESH DN+L +P PFL TN+IGT+T+LEA RRH VR HHIST
Sbjct  62   AAVVDPLVAEADAVVHYAAESHNDNSLHDPRPFLDTNIIGTYTLLEAARRHDVRFHHIST  121

Query  121  DEVYGDLELDDRARFTESTPYNPSSPYSATKAGADMLVRAWVRSYGVRATISNCSNNYGP  180
            DEVYGDLELDD ARFTESTPYNPSSPYS+TKAG+D+LVRAWVRS+GVRATISNCSNNYGP
Sbjct  122  DEVYGDLELDDPARFTESTPYNPSSPYSSTKAGSDLLVRAWVRSFGVRATISNCSNNYGP  181

Query  181  YQHVEKFIPRQITNVLTGRRPKLYGAGANVRDWIHVDDHNSAVRRILDRGRIGRTYLISS  240
            YQHVEKFIPRQITNVL G RPKLYG G NVRDWIH DDH+SAV  ILD+G IG+TYLI +
Sbjct  182  YQHVEKFIPRQITNVLRGIRPKLYGTGENVRDWIHADDHSSAVLTILDKGEIGQTYLIGA  241

Query  241  EGERDNLTVLRTLLRLMDRDPDDFDHVTDRVGHDLRYAIDPSTLYDELCWAPKHTDFEEG  300
            +GE+DN TV+  +L+L  +  D +D VTDR GHDLRYAID + L  EL WAP + DFE G
Sbjct  242  DGEKDNKTVVELILQLSGQPVDAYDLVTDRPGHDLRYAIDSTKLRTELGWAPTYGDFESG  301

Query  301  LRTTIDWYRDNESWWRPLKDATEARYQERGQ  331
            L  TIDWYRDNESWW P KD  EA Y  +GQ
Sbjct  302  LAATIDWYRDNESWWAPTKDGVEAFYASKGQ  332


>gi|226303739|ref|YP_002763697.1| dTDP-glucose 4,6-dehydratase [Rhodococcus erythropolis PR4]
 gi|226182854|dbj|BAH30958.1| dTDP-glucose 4,6-dehydratase [Rhodococcus erythropolis PR4]
Length=335

 Score =  482 bits (1241),  Expect = 3e-134, Method: Compositional matrix adjust.
 Identities = 231/331 (70%), Positives = 265/331 (81%), Gaps = 0/331 (0%)

Query  1    MRLLVTGGAGFIGTNFVHSAVREHPDDAVTVLDALTYAGRRESLADVEDAIRLVQGDITD  60
            MR+LVTGGAGFIG NFVH  V E PD  VTVLDALTYAG + SL  + D I  V GDITD
Sbjct  1    MRVLVTGGAGFIGANFVHQTVAERPDAEVTVLDALTYAGNKSSLDSIADRITFVHGDITD  60

Query  61   AELVSQLVAESDAVVHFAAESHVDNALDNPEPFLHTNVIGTFTILEAVRRHGVRLHHIST  120
            A LV +LV  +D VVHFAAESH DN+L +P PF+ TN++GTFT+L+AVR+H VR HHIST
Sbjct  61   AVLVDELVGAADVVVHFAAESHNDNSLADPWPFVQTNIVGTFTLLQAVRKHDVRYHHIST  120

Query  121  DEVYGDLELDDRARFTESTPYNPSSPYSATKAGADMLVRAWVRSYGVRATISNCSNNYGP  180
            DEVYGDLEL D  RFTEST YNPSSPYS+TKA +DMLVRAW RS+GVRAT+SNCSNNYGP
Sbjct  121  DEVYGDLELGDPDRFTESTAYNPSSPYSSTKASSDMLVRAWTRSFGVRATLSNCSNNYGP  180

Query  181  YQHVEKFIPRQITNVLTGRRPKLYGAGANVRDWIHVDDHNSAVRRILDRGRIGRTYLISS  240
            YQHVEKFIPRQITNVL G RPKLYG G NVRDWIHVDDHNSAV  I+D GRIG+TYLI +
Sbjct  181  YQHVEKFIPRQITNVLAGLRPKLYGDGLNVRDWIHVDDHNSAVWAIIDGGRIGQTYLIGA  240

Query  241  EGERDNLTVLRTLLRLMDRDPDDFDHVTDRVGHDLRYAIDPSTLYDELCWAPKHTDFEEG  300
            +GE +N TV+ ++L+++ R  D+FD VTDR GHD+RYAID S L  EL W+P++ DF  G
Sbjct  241  DGEVNNRTVMESILQILGRGADEFDFVTDRPGHDVRYAIDSSLLRKELGWSPRYEDFRSG  300

Query  301  LRTTIDWYRDNESWWRPLKDATEARYQERGQ  331
            L  TIDWYRDNE WWRP KDATE  Y   G+
Sbjct  301  LEATIDWYRDNEQWWRPQKDATEQAYVAAGE  331


>gi|256856008|emb|CBB12353.1| RmlB protein [Rhodococcus aetherivorans]
Length=338

 Score =  481 bits (1238),  Expect = 6e-134, Method: Compositional matrix adjust.
 Identities = 236/331 (72%), Positives = 266/331 (81%), Gaps = 0/331 (0%)

Query  1    MRLLVTGGAGFIGTNFVHSAVREHPDDAVTVLDALTYAGRRESLADVEDAIRLVQGDITD  60
            MRLLVTGGAGFIG NFVH  V + P+  VTVLD LTYAG   SL  V + IR V+GD+ D
Sbjct  1    MRLLVTGGAGFIGANFVHRTVADRPEARVTVLDKLTYAGNLASLDPVAEKIRFVRGDVAD  60

Query  61   AELVSQLVAESDAVVHFAAESHVDNALDNPEPFLHTNVIGTFTILEAVRRHGVRLHHIST  120
            A+LV  LVAESD VVHFAAESH DN+L +P PF+ TN+IGTFT+LEAVRRH VR HHIST
Sbjct  61   ADLVDALVAESDLVVHFAAESHNDNSLADPSPFVQTNLIGTFTLLEAVRRHSVRYHHIST  120

Query  121  DEVYGDLELDDRARFTESTPYNPSSPYSATKAGADMLVRAWVRSYGVRATISNCSNNYGP  180
            DEVYGDLELDD ARFTE+T YNPSSPYS+TKAG+D+LVRAWVRS+GV ATISNCSNNYGP
Sbjct  121  DEVYGDLELDDPARFTEATAYNPSSPYSSTKAGSDLLVRAWVRSFGVAATISNCSNNYGP  180

Query  181  YQHVEKFIPRQITNVLTGRRPKLYGAGANVRDWIHVDDHNSAVRRILDRGRIGRTYLISS  240
            YQHVEKFIPRQITNVL G RPKLYG GANVRDWIHVDDHN AV  I+D+G IG+TYLI +
Sbjct  181  YQHVEKFIPRQITNVLDGIRPKLYGTGANVRDWIHVDDHNRAVWTIIDKGEIGQTYLIGA  240

Query  241  EGERDNLTVLRTLLRLMDRDPDDFDHVTDRVGHDLRYAIDPSTLYDELCWAPKHTDFEEG  300
            +GE +N TV+ T+L L  +D  DFD VTDR GHDLRYAID + L  EL W P++ DF EG
Sbjct  241  DGETNNRTVVETILELCGKDRGDFDFVTDRPGHDLRYAIDATRLRTELGWTPRYRDFREG  300

Query  301  LRTTIDWYRDNESWWRPLKDATEARYQERGQ  331
            L  TIDWYR +E WWRP KDATE  Y   G+
Sbjct  301  LAATIDWYRTHEHWWRPQKDATEHAYARSGE  331


>gi|229492624|ref|ZP_04386427.1| dTDP-glucose 4,6-dehydratase [Rhodococcus erythropolis SK121]
 gi|229320610|gb|EEN86428.1| dTDP-glucose 4,6-dehydratase [Rhodococcus erythropolis SK121]
Length=334

 Score =  481 bits (1238),  Expect = 7e-134, Method: Compositional matrix adjust.
 Identities = 230/326 (71%), Positives = 261/326 (81%), Gaps = 0/326 (0%)

Query  1    MRLLVTGGAGFIGTNFVHSAVREHPDDAVTVLDALTYAGRRESLADVEDAIRLVQGDITD  60
            MRLLVTGGAGFIG NFVH  V   PD  VTVLDALTYAG R+SLA VE+ I  V G++ D
Sbjct  1    MRLLVTGGAGFIGANFVHQTVATRPDVEVTVLDALTYAGNRQSLASVEERITFVHGNVAD  60

Query  61   AELVSQLVAESDAVVHFAAESHVDNALDNPEPFLHTNVIGTFTILEAVRRHGVRLHHIST  120
              LV  LV+ SDAVVHFAAESH DN+L +PEPFL TNV+GTF++L+AVR HGVR HHIST
Sbjct  61   EPLVDDLVSRSDAVVHFAAESHNDNSLADPEPFLRTNVMGTFSLLQAVRSHGVRYHHIST  120

Query  121  DEVYGDLELDDRARFTESTPYNPSSPYSATKAGADMLVRAWVRSYGVRATISNCSNNYGP  180
            DEVYGDLELDD A+FTE+TPYNPSSPYSA+KA +D+ VRAWVRS+G+ ATISNCSNNYGP
Sbjct  121  DEVYGDLELDDPAKFTETTPYNPSSPYSASKASSDLFVRAWVRSFGIAATISNCSNNYGP  180

Query  181  YQHVEKFIPRQITNVLTGRRPKLYGAGANVRDWIHVDDHNSAVRRILDRGRIGRTYLISS  240
            YQHVEKFIPRQITN+L G RP+LYG G NVRDWIHV+DHN AV  ILDRG+ G TYLI +
Sbjct  181  YQHVEKFIPRQITNLLDGVRPRLYGEGRNVRDWIHVEDHNRAVWDILDRGKSGETYLIGA  240

Query  241  EGERDNLTVLRTLLRLMDRDPDDFDHVTDRVGHDLRYAIDPSTLYDELCWAPKHTDFEEG  300
            +GE DN TV+ TLL +  R PDDFD VTDR GHDLRYAID + L  EL W P++ DF  G
Sbjct  241  DGETDNRTVIATLLEIFGRKPDDFDFVTDRPGHDLRYAIDSTRLQQELGWKPQYRDFRSG  300

Query  301  LRTTIDWYRDNESWWRPLKDATEARY  326
            L  T++WYRDNE WWRP K   EA Y
Sbjct  301  LEATVEWYRDNEQWWRPQKAGVEATY  326


>gi|311742182|ref|ZP_07715992.1| dTDP-glucose 4,6-dehydratase [Aeromicrobium marinum DSM 15272]
 gi|311314675|gb|EFQ84582.1| dTDP-glucose 4,6-dehydratase [Aeromicrobium marinum DSM 15272]
Length=334

 Score =  480 bits (1236),  Expect = 1e-133, Method: Compositional matrix adjust.
 Identities = 235/331 (71%), Positives = 267/331 (81%), Gaps = 2/331 (0%)

Query  2    RLLVTGGAGFIGTNFVHSAVREHPDDAVTVLDALTYAGRRESLADV-EDAIRLVQGDITD  60
            RLLVTGGAGFIG+NFVH  V  H D  V VLDALTYAG R SL  + +D ++ V GDITD
Sbjct  5    RLLVTGGAGFIGSNFVHH-VLGHTDHDVVVLDALTYAGNRASLEGLPQDRLQFVHGDITD  63

Query  61   AELVSQLVAESDAVVHFAAESHVDNALDNPEPFLHTNVIGTFTILEAVRRHGVRLHHIST  120
            A+LV +LV E DAVVH+AAESH DN+LDNP PFL TN+IGT+T+LEA RRHG R HHIST
Sbjct  64   ADLVDRLVGECDAVVHYAAESHNDNSLDNPRPFLDTNIIGTYTLLEAARRHGTRFHHIST  123

Query  121  DEVYGDLELDDRARFTESTPYNPSSPYSATKAGADMLVRAWVRSYGVRATISNCSNNYGP  180
            DEVYGDLELDD  RFTE TPYNPSSPYS+TKAG+D+LVRAWVRS+GVRATISNCSNNYGP
Sbjct  124  DEVYGDLELDDPERFTEQTPYNPSSPYSSTKAGSDLLVRAWVRSFGVRATISNCSNNYGP  183

Query  181  YQHVEKFIPRQITNVLTGRRPKLYGAGANVRDWIHVDDHNSAVRRILDRGRIGRTYLISS  240
            YQHVEKFIPRQ+TNVL G RPKLYGAG NVRDWIH DDH+SAV  +LDRG IG TYLI +
Sbjct  184  YQHVEKFIPRQVTNVLRGIRPKLYGAGENVRDWIHADDHSSAVLAVLDRGVIGETYLIGA  243

Query  241  EGERDNLTVLRTLLRLMDRDPDDFDHVTDRVGHDLRYAIDPSTLYDELCWAPKHTDFEEG  300
            +GER+N  V+  +L  M R  D +DHVTDR GHDLRYAID + L  EL W P+  DFE G
Sbjct  244  DGERNNKDVVELILTTMGRPADAYDHVTDRAGHDLRYAIDSTRLRTELGWTPQFQDFEAG  303

Query  301  LRTTIDWYRDNESWWRPLKDATEARYQERGQ  331
            L  T+DWYR++E+WW P KDATEA Y  +GQ
Sbjct  304  LAATVDWYREHEAWWAPAKDATEAFYASKGQ  334


>gi|257067485|ref|YP_003153740.1| dTDP-glucose 4,6-dehydratase [Brachybacterium faecium DSM 4810]
 gi|256558303|gb|ACU84150.1| dTDP-glucose 4,6-dehydratase [Brachybacterium faecium DSM 4810]
Length=334

 Score =  477 bits (1228),  Expect = 1e-132, Method: Compositional matrix adjust.
 Identities = 232/330 (71%), Positives = 267/330 (81%), Gaps = 2/330 (0%)

Query  3    LLVTGGAGFIGTNFVHSAVREHPDDAVTVLDALTYAGRRESLADVEDA-IRLVQGDITDA  61
            LLVTGGAGFIG+ FVH  +  H DD VTVLD LTYAG R SL D+    +RLV GD+ DA
Sbjct  6    LLVTGGAGFIGSAFVHHVI-AHTDDTVTVLDKLTYAGHRSSLEDLPSRRVRLVVGDVADA  64

Query  62   ELVSQLVAESDAVVHFAAESHVDNALDNPEPFLHTNVIGTFTILEAVRRHGVRLHHISTD  121
              V  LVA +DAVVHFAAESH DN+L +P PFL TN++GT+T+LEAVRRHG R HHISTD
Sbjct  65   ATVEPLVAAADAVVHFAAESHNDNSLSDPSPFLQTNLVGTYTLLEAVRRHGARFHHISTD  124

Query  122  EVYGDLELDDRARFTESTPYNPSSPYSATKAGADMLVRAWVRSYGVRATISNCSNNYGPY  181
            EVYGDL LDD  RFTE+TPYNPSSPYSATKAG+D+LVRAWVRS+GV+AT+SNCSNNYGP 
Sbjct  125  EVYGDLALDDPDRFTETTPYNPSSPYSATKAGSDLLVRAWVRSFGVQATLSNCSNNYGPR  184

Query  182  QHVEKFIPRQITNVLTGRRPKLYGAGANVRDWIHVDDHNSAVRRILDRGRIGRTYLISSE  241
            QHVEKFIPRQITN++ G RP+LYGAGANVRDWIH +DH+SAV RIL+ G  GRTYLI ++
Sbjct  185  QHVEKFIPRQITNLIDGIRPRLYGAGANVRDWIHAEDHSSAVLRILEAGESGRTYLIGAD  244

Query  242  GERDNLTVLRTLLRLMDRDPDDFDHVTDRVGHDLRYAIDPSTLYDELCWAPKHTDFEEGL  301
            GE+ N  V+  +LRLM R  DD+DHVTDR GHDLRYAID + L +EL WAP+  DFE GL
Sbjct  245  GEKSNKEVVELILRLMGRPDDDYDHVTDRPGHDLRYAIDATALREELGWAPRFRDFEAGL  304

Query  302  RTTIDWYRDNESWWRPLKDATEARYQERGQ  331
              TIDWYR+NE WWRP K ATEA+YQ  GQ
Sbjct  305  AATIDWYRENEGWWRPQKAATEAKYQLTGQ  334


>gi|333917811|ref|YP_004491392.1| dTDP-glucose 4,6-dehydratase [Amycolicicoccus subflavus DQS3-9A1]
 gi|333480032|gb|AEF38592.1| dTDP-glucose 4,6-dehydratase [Amycolicicoccus subflavus DQS3-9A1]
Length=332

 Score =  476 bits (1224),  Expect = 3e-132, Method: Compositional matrix adjust.
 Identities = 233/331 (71%), Positives = 259/331 (79%), Gaps = 0/331 (0%)

Query  1    MRLLVTGGAGFIGTNFVHSAVREHPDDAVTVLDALTYAGRRESLADVEDAIRLVQGDITD  60
            MRLLVTGGAGFIG NFVH  VR+HPD  VTVLD LTYAG +ESLA V   I  V GD+ D
Sbjct  1    MRLLVTGGAGFIGANFVHLTVRDHPDVQVTVLDKLTYAGHKESLAPVGGHIEFVHGDVAD  60

Query  61   AELVSQLVAESDAVVHFAAESHVDNALDNPEPFLHTNVIGTFTILEAVRRHGVRLHHIST  120
              LV +LVA++D VVHFAAESH DN+L  PEPF++TN++GTFT+LEAVR HGVRLHHIST
Sbjct  61   FPLVDRLVAQADFVVHFAAESHNDNSLRGPEPFINTNIVGTFTLLEAVRSHGVRLHHIST  120

Query  121  DEVYGDLELDDRARFTESTPYNPSSPYSATKAGADMLVRAWVRSYGVRATISNCSNNYGP  180
            DEV+GDLELDD  RF E T YNPSSPYSA+KA AD+LVRAWVRS+GV ATISNCSNNYGP
Sbjct  121  DEVFGDLELDDPQRFDEVTAYNPSSPYSASKASADLLVRAWVRSFGVHATISNCSNNYGP  180

Query  181  YQHVEKFIPRQITNVLTGRRPKLYGAGANVRDWIHVDDHNSAVRRILDRGRIGRTYLISS  240
            YQHVEKFIPRQITN+LTG RPKLYG G NVRDWIHVDDHN AV  IL++G  G TYLI +
Sbjct  181  YQHVEKFIPRQITNILTGVRPKLYGEGLNVRDWIHVDDHNRAVWTILEKGTAGETYLIGA  240

Query  241  EGERDNLTVLRTLLRLMDRDPDDFDHVTDRVGHDLRYAIDPSTLYDELCWAPKHTDFEEG  300
            +GE  N  VL  +L LM    DDFDHV DR GHDLRYAI+ S L  EL W P+  DF +G
Sbjct  241  DGEESNRNVLALILDLMGCGADDFDHVADRPGHDLRYAINSSKLRSELGWKPEFRDFRDG  300

Query  301  LRTTIDWYRDNESWWRPLKDATEARYQERGQ  331
            L  TIDWYR NE+WWRP KDATE  Y    Q
Sbjct  301  LAATIDWYRLNEAWWRPFKDATERAYDRGSQ  331


>gi|255327300|ref|ZP_05368374.1| dTDP-glucose 4,6-dehydratase [Rothia mucilaginosa ATCC 25296]
 gi|255295580|gb|EET74923.1| dTDP-glucose 4,6-dehydratase [Rothia mucilaginosa ATCC 25296]
Length=338

 Score =  475 bits (1222),  Expect = 4e-132, Method: Compositional matrix adjust.
 Identities = 223/330 (68%), Positives = 267/330 (81%), Gaps = 2/330 (0%)

Query  3    LLVTGGAGFIGTNFVHSAVREHPDDAVTVLDALTYAGRRESLADV-EDAIRLVQGDITDA  61
            +LVTGGAGFIG+NFVH  + ++ D  +TVLD +TYA    SL  + E   +LV GDI D 
Sbjct  10   ILVTGGAGFIGSNFVHHLI-DNTDHTITVLDKMTYAANAASLEGLPESRFKLVVGDIADR  68

Query  62   ELVSQLVAESDAVVHFAAESHVDNALDNPEPFLHTNVIGTFTILEAVRRHGVRLHHISTD  121
            EL  +LV ++DAVVH+AAESH DN+L NPEPF+HTN+IGTF++LEAVR+HG R HHISTD
Sbjct  69   ELADELVGKADAVVHYAAESHNDNSLSNPEPFIHTNLIGTFSLLEAVRKHGTRYHHISTD  128

Query  122  EVYGDLELDDRARFTESTPYNPSSPYSATKAGADMLVRAWVRSYGVRATISNCSNNYGPY  181
            EV+GDLELDD A+FTE+TPYNPSSPYS+TKAG+D+LVRAWVRS+G+ ATISNCSNNYGPY
Sbjct  129  EVFGDLELDDPAKFTETTPYNPSSPYSSTKAGSDLLVRAWVRSFGIEATISNCSNNYGPY  188

Query  182  QHVEKFIPRQITNVLTGRRPKLYGAGANVRDWIHVDDHNSAVRRILDRGRIGRTYLISSE  241
            QH+EKFIPRQITN+L+G  PKLYG G NVRDWIH  DH+SAV RIL++G+IG TYLI ++
Sbjct  189  QHIEKFIPRQITNILSGLTPKLYGEGLNVRDWIHASDHSSAVLRILEQGKIGETYLIGAD  248

Query  242  GERDNLTVLRTLLRLMDRDPDDFDHVTDRVGHDLRYAIDPSTLYDELCWAPKHTDFEEGL  301
            GE +N+TVLRT+LRLM +D +DF+HV DR GHDLRYAID S L  EL W PK TDFE GL
Sbjct  249  GEENNITVLRTILRLMGKDENDFEHVVDRPGHDLRYAIDGSRLRAELGWEPKFTDFESGL  308

Query  302  RTTIDWYRDNESWWRPLKDATEARYQERGQ  331
              TI WY DN  WW PLK   EA+Y + GQ
Sbjct  309  ADTIKWYTDNRGWWEPLKAEVEAKYAKAGQ  338


>gi|309812220|ref|ZP_07705978.1| dTDP-glucose 4,6-dehydratase [Dermacoccus sp. Ellin185]
 gi|308433907|gb|EFP57781.1| dTDP-glucose 4,6-dehydratase [Dermacoccus sp. Ellin185]
Length=341

 Score =  474 bits (1220),  Expect = 7e-132, Method: Compositional matrix adjust.
 Identities = 227/329 (69%), Positives = 268/329 (82%), Gaps = 0/329 (0%)

Query  1    MRLLVTGGAGFIGTNFVHSAVREHPDDAVTVLDALTYAGRRESLADVEDAIRLVQGDITD  60
            M++LVTGGAGFIG NFVH  V+E P+  + VLDA+TYAG   SL  + + + LV+GDI D
Sbjct  1    MQILVTGGAGFIGGNFVHLTVKERPEARIVVLDAMTYAGNERSLDGLGEHVELVRGDIAD  60

Query  61   AELVSQLVAESDAVVHFAAESHVDNALDNPEPFLHTNVIGTFTILEAVRRHGVRLHHIST  120
            A LV +LVA SD VVHFAAESH DN+L  P PF+ TN++GT+T+LEA R+H VR HHIST
Sbjct  61   AALVDRLVAASDLVVHFAAESHNDNSLAEPWPFVQTNIVGTYTLLEAARKHDVRYHHIST  120

Query  121  DEVYGDLELDDRARFTESTPYNPSSPYSATKAGADMLVRAWVRSYGVRATISNCSNNYGP  180
            DEVYGDLELDD  RFTE+T YNPSSPYS+TKAG+DMLVRA VRS+GVRATISNCSNNYGP
Sbjct  121  DEVYGDLELDDPERFTEATAYNPSSPYSSTKAGSDMLVRACVRSFGVRATISNCSNNYGP  180

Query  181  YQHVEKFIPRQITNVLTGRRPKLYGAGANVRDWIHVDDHNSAVRRILDRGRIGRTYLISS  240
             QH+EKFIPRQITN++ G RPKLYG G NVRDWIHVDDHN+AV  I++RGRIG TYLI +
Sbjct  181  RQHIEKFIPRQITNLIDGVRPKLYGDGLNVRDWIHVDDHNAAVWAIIERGRIGETYLIGA  240

Query  241  EGERDNLTVLRTLLRLMDRDPDDFDHVTDRVGHDLRYAIDPSTLYDELCWAPKHTDFEEG  300
            +GE DN TV++ +L  M RD DDFDHVTDR GHD RYAID + L +EL W+P++T FEEG
Sbjct  241  DGELDNKTVVQAILTGMGRDADDFDHVTDRPGHDRRYAIDSTKLREELGWSPRYTSFEEG  300

Query  301  LRTTIDWYRDNESWWRPLKDATEARYQER  329
            L  TI WYRDNESWWRP KD TEA+Y ++
Sbjct  301  LAATIQWYRDNESWWRPFKDETEAKYADQ  329


>gi|111021081|ref|YP_704053.1| dTDP-glucose 4,6-dehydratase [Rhodococcus jostii RHA1]
 gi|110820611|gb|ABG95895.1| dTDP-glucose 4,6-dehydratase [Rhodococcus jostii RHA1]
Length=334

 Score =  474 bits (1219),  Expect = 1e-131, Method: Compositional matrix adjust.
 Identities = 229/326 (71%), Positives = 260/326 (80%), Gaps = 0/326 (0%)

Query  1    MRLLVTGGAGFIGTNFVHSAVREHPDDAVTVLDALTYAGRRESLADVEDAIRLVQGDITD  60
            MRLLVTGGAGFIG NFVH  V E PD  VTVLDALTYAG R SL  V D I  V GD+ D
Sbjct  1    MRLLVTGGAGFIGANFVHQTVAERPDVQVTVLDALTYAGNRRSLDPVSDRIEFVHGDVAD  60

Query  61   AELVSQLVAESDAVVHFAAESHVDNALDNPEPFLHTNVIGTFTILEAVRRHGVRLHHIST  120
              LV +LV +SDAVVHFAAESH DN+L +P PF+ TNVIGTF++L+AVR H VR HHIST
Sbjct  61   FALVDRLVGDSDAVVHFAAESHNDNSLADPTPFVQTNVIGTFSLLQAVRAHDVRYHHIST  120

Query  121  DEVYGDLELDDRARFTESTPYNPSSPYSATKAGADMLVRAWVRSYGVRATISNCSNNYGP  180
            DEVYGDLELDD  RFTESTPYNPSSPYSATKA +D+LVRAW RS+GVRAT+SNCSNNYGP
Sbjct  121  DEVYGDLELDDPERFTESTPYNPSSPYSATKASSDLLVRAWARSFGVRATLSNCSNNYGP  180

Query  181  YQHVEKFIPRQITNVLTGRRPKLYGAGANVRDWIHVDDHNSAVRRILDRGRIGRTYLISS  240
            YQHVEKFIPRQITN++ G RP+LYG+G NVRDWIHVDDHN+AV  IL++G +G+TYLI +
Sbjct  181  YQHVEKFIPRQITNLIDGVRPRLYGSGKNVRDWIHVDDHNAAVWTILEKGSLGQTYLIGA  240

Query  241  EGERDNLTVLRTLLRLMDRDPDDFDHVTDRVGHDLRYAIDPSTLYDELCWAPKHTDFEEG  300
            +GE DN TV+ TLL L  RD DD D VTDR GHDLRYAID + L  EL W P++ DF  G
Sbjct  241  DGEVDNRTVVGTLLELFGRDADDLDFVTDRPGHDLRYAIDSTRLRTELGWTPQYKDFRSG  300

Query  301  LRTTIDWYRDNESWWRPLKDATEARY  326
            L  T+ WYRDNESWWR  K++ E  Y
Sbjct  301  LEATVRWYRDNESWWRAQKESAEKAY  326


>gi|283458591|ref|YP_003363224.1| dTDP-D-glucose 4,6-dehydratase [Rothia mucilaginosa DY-18]
 gi|283134639|dbj|BAI65404.1| dTDP-D-glucose 4,6-dehydratase [Rothia mucilaginosa DY-18]
Length=332

 Score =  473 bits (1218),  Expect = 1e-131, Method: Compositional matrix adjust.
 Identities = 222/330 (68%), Positives = 267/330 (81%), Gaps = 2/330 (0%)

Query  3    LLVTGGAGFIGTNFVHSAVREHPDDAVTVLDALTYAGRRESLADV-EDAIRLVQGDITDA  61
            +LVTGGAGFIG+NFVH  + ++ D  +TVLD +TYA    SL  + E   +LV GDI D 
Sbjct  4    ILVTGGAGFIGSNFVHHLI-DNTDHTITVLDKMTYAANAASLEGLPESRFKLVVGDIADR  62

Query  62   ELVSQLVAESDAVVHFAAESHVDNALDNPEPFLHTNVIGTFTILEAVRRHGVRLHHISTD  121
            EL  +LV ++DAVVH+AAESH DN+L NPEPF+HTN+IGTF++LEAVR+HG R HHISTD
Sbjct  63   ELADELVGKADAVVHYAAESHNDNSLSNPEPFIHTNLIGTFSLLEAVRKHGTRYHHISTD  122

Query  122  EVYGDLELDDRARFTESTPYNPSSPYSATKAGADMLVRAWVRSYGVRATISNCSNNYGPY  181
            EV+GDLELDD A+FTE+TPYNPSSPYS+TKAG+D+LVRAWVRS+G+ ATISNCSNNYGPY
Sbjct  123  EVFGDLELDDPAKFTETTPYNPSSPYSSTKAGSDLLVRAWVRSFGIEATISNCSNNYGPY  182

Query  182  QHVEKFIPRQITNVLTGRRPKLYGAGANVRDWIHVDDHNSAVRRILDRGRIGRTYLISSE  241
            QH+EKFIPRQITN+L+G  PKLYG G NVRDWIH  DH+SAV RIL++G+IG TYLI ++
Sbjct  183  QHIEKFIPRQITNILSGLTPKLYGEGLNVRDWIHASDHSSAVLRILEQGKIGETYLIGAD  242

Query  242  GERDNLTVLRTLLRLMDRDPDDFDHVTDRVGHDLRYAIDPSTLYDELCWAPKHTDFEEGL  301
            GE +N+TVLRT+LRLM +D +DF+HV DR GHDLRYAID S L  EL W PK TDFE GL
Sbjct  243  GEENNITVLRTILRLMGKDENDFEHVVDRPGHDLRYAIDGSRLRAELGWEPKFTDFESGL  302

Query  302  RTTIDWYRDNESWWRPLKDATEARYQERGQ  331
              TI WY +N  WW PLK   EA+Y + GQ
Sbjct  303  ADTIKWYTENRGWWEPLKAEVEAKYAKAGQ  332


>gi|84498710|ref|ZP_00997451.1| putative dTDP-D-glucose 4,6-dehydratase [Janibacter sp. HTCC2649]
 gi|84498715|ref|ZP_00997456.1| putative dTDP-D-glucose 4,6-dehydratase [Janibacter sp. HTCC2649]
 gi|84381010|gb|EAP96898.1| putative dTDP-D-glucose 4,6-dehydratase [Janibacter sp. HTCC2649]
 gi|84381015|gb|EAP96903.1| putative dTDP-D-glucose 4,6-dehydratase [Janibacter sp. HTCC2649]
Length=335

 Score =  473 bits (1217),  Expect = 2e-131, Method: Compositional matrix adjust.
 Identities = 232/326 (72%), Positives = 263/326 (81%), Gaps = 0/326 (0%)

Query  1    MRLLVTGGAGFIGTNFVHSAVREHPDDAVTVLDALTYAGRRESLADVEDAIRLVQGDITD  60
            MR+LVTGGAGFIG+NFVH  +   P   VTVLDALTYAG R SL  + D +RLV+GDITD
Sbjct  1    MRILVTGGAGFIGSNFVHLTLATRPGCEVTVLDALTYAGHRASLDGLGDRVRLVEGDITD  60

Query  61   AELVSQLVAESDAVVHFAAESHVDNALDNPEPFLHTNVIGTFTILEAVRRHGVRLHHIST  120
              LV +LV+E D VVHFAAESH DN+L +P PF+HTNVIGTFT++EAVRRH V  HH+ST
Sbjct  61   LTLVDRLVSEHDLVVHFAAESHNDNSLADPWPFVHTNVIGTFTLVEAVRRHAVHYHHVST  120

Query  121  DEVYGDLELDDRARFTESTPYNPSSPYSATKAGADMLVRAWVRSYGVRATISNCSNNYGP  180
            DEVYGDLELDD  RFTE+T YNPSSPYSATK  +D+LVRAWVRS+G++ATISNCSNNYGP
Sbjct  121  DEVYGDLELDDPGRFTEATAYNPSSPYSATKGASDLLVRAWVRSFGLQATISNCSNNYGP  180

Query  181  YQHVEKFIPRQITNVLTGRRPKLYGAGANVRDWIHVDDHNSAVRRILDRGRIGRTYLISS  240
             QHVEKFIPRQITN+L G RPKLYG G NVRDWIHVDDHN AV  I+DRG+IG TYLI +
Sbjct  181  RQHVEKFIPRQITNILDGVRPKLYGDGLNVRDWIHVDDHNRAVWAIIDRGQIGETYLIGA  240

Query  241  EGERDNLTVLRTLLRLMDRDPDDFDHVTDRVGHDLRYAIDPSTLYDELCWAPKHTDFEEG  300
            +GE DN TV+R +L LM  D D FDHVTDR GHD RYAID S L  EL W P++  F EG
Sbjct  241  DGEVDNGTVVRDILGLMGEDADAFDHVTDRPGHDRRYAIDSSRLRTELGWTPEYPSFREG  300

Query  301  LRTTIDWYRDNESWWRPLKDATEARY  326
            L  TIDWYRDNE WWRP+KDATE +Y
Sbjct  301  LAATIDWYRDNEEWWRPMKDATERKY  326


>gi|226363371|ref|YP_002781153.1| dTDP-glucose 4,6-dehydratase [Rhodococcus opacus B4]
 gi|226241860|dbj|BAH52208.1| dTDP-glucose 4,6-dehydratase [Rhodococcus opacus B4]
Length=334

 Score =  473 bits (1217),  Expect = 2e-131, Method: Compositional matrix adjust.
 Identities = 229/326 (71%), Positives = 260/326 (80%), Gaps = 0/326 (0%)

Query  1    MRLLVTGGAGFIGTNFVHSAVREHPDDAVTVLDALTYAGRRESLADVEDAIRLVQGDITD  60
            MRLLVTGGAGFIG NFVH  V E PD  VTVLDALTYAG R SL  V D I  V GD+ D
Sbjct  1    MRLLVTGGAGFIGANFVHQTVAERPDVQVTVLDALTYAGNRRSLDAVADRIEFVHGDVAD  60

Query  61   AELVSQLVAESDAVVHFAAESHVDNALDNPEPFLHTNVIGTFTILEAVRRHGVRLHHIST  120
              LV +LVA SDAVVHFAAESH DN+L +P PF+ TNVIGTF++L+AVR H VR HHIST
Sbjct  61   FALVDRLVAASDAVVHFAAESHNDNSLADPTPFVQTNVIGTFSLLQAVRAHDVRYHHIST  120

Query  121  DEVYGDLELDDRARFTESTPYNPSSPYSATKAGADMLVRAWVRSYGVRATISNCSNNYGP  180
            DEVYGDLELDD  RFTESTPYNPSSPYSATKA +D+LVRAW RS+GVRAT+SNCSNNYGP
Sbjct  121  DEVYGDLELDDPERFTESTPYNPSSPYSATKASSDLLVRAWARSFGVRATLSNCSNNYGP  180

Query  181  YQHVEKFIPRQITNVLTGRRPKLYGAGANVRDWIHVDDHNSAVRRILDRGRIGRTYLISS  240
            YQHVEKFIPRQITN++ G RP+LYG+G NVRDWIHVDDHN+AV  IL++G +G+TYLI +
Sbjct  181  YQHVEKFIPRQITNLIDGVRPRLYGSGKNVRDWIHVDDHNAAVWTILEKGTLGQTYLIGA  240

Query  241  EGERDNLTVLRTLLRLMDRDPDDFDHVTDRVGHDLRYAIDPSTLYDELCWAPKHTDFEEG  300
            +GE DN TV+ TLL +  RD +D D VTDR GHDLRYAID + L  EL W P++ DF  G
Sbjct  241  DGEVDNRTVVGTLLEVFGRDTNDLDFVTDRPGHDLRYAIDSTRLRTELGWTPQYEDFRSG  300

Query  301  LRTTIDWYRDNESWWRPLKDATEARY  326
            L  T+ WYRDNESWWRP K + E  Y
Sbjct  301  LEATVRWYRDNESWWRPQKASAEKAY  326


>gi|145223883|ref|YP_001134561.1| dTDP-glucose 4,6-dehydratase [Mycobacterium gilvum PYR-GCK]
 gi|315444212|ref|YP_004077091.1| dTDP-glucose 4,6-dehydratase [Mycobacterium sp. Spyr1]
 gi|145216369|gb|ABP45773.1| dTDP-glucose 4,6-dehydratase [Mycobacterium gilvum PYR-GCK]
 gi|315262515|gb|ADT99256.1| dTDP-glucose 4,6-dehydratase [Mycobacterium sp. Spyr1]
Length=332

 Score =  473 bits (1216),  Expect = 2e-131, Method: Compositional matrix adjust.
 Identities = 234/331 (71%), Positives = 267/331 (81%), Gaps = 2/331 (0%)

Query  2    RLLVTGGAGFIGTNFVHSAVREHPDDAVTVLDALTYAGRRESLADV-EDAIRLVQGDITD  60
            RLLVTGGAGFIG+NFVH  V  H D  VTVLD LTYAG R SL  + E  +  V GD+ D
Sbjct  3    RLLVTGGAGFIGSNFVHH-VLAHTDHHVTVLDKLTYAGNRASLDGLPERRLDFVHGDVAD  61

Query  61   AELVSQLVAESDAVVHFAAESHVDNALDNPEPFLHTNVIGTFTILEAVRRHGVRLHHIST  120
            A+LV +LVA +DAVVH+AAESH DN+LD PEPFLH+NVIGTFT+LEAVRRHG RLHH+ST
Sbjct  62   ADLVDELVAGTDAVVHYAAESHNDNSLDRPEPFLHSNVIGTFTVLEAVRRHGRRLHHVST  121

Query  121  DEVYGDLELDDRARFTESTPYNPSSPYSATKAGADMLVRAWVRSYGVRATISNCSNNYGP  180
            DEVYGDLELDD ARFTES+PYNPSSPYS+TKAG+D+LVRAW RS+GV ATISNCSNNYGP
Sbjct  122  DEVYGDLELDDPARFTESSPYNPSSPYSSTKAGSDLLVRAWTRSFGVAATISNCSNNYGP  181

Query  181  YQHVEKFIPRQITNVLTGRRPKLYGAGANVRDWIHVDDHNSAVRRILDRGRIGRTYLISS  240
            YQHVEKFIPRQITNVL G RP+LYG G NVRDWIH DDH+SAV  IL++GRIG TYLI +
Sbjct  182  YQHVEKFIPRQITNVLWGIRPRLYGEGRNVRDWIHADDHSSAVLLILEKGRIGETYLIGA  241

Query  241  EGERDNLTVLRTLLRLMDRDPDDFDHVTDRVGHDLRYAIDPSTLYDELCWAPKHTDFEEG  300
             GE+DN TV+  +L LM  D D +D V DR+GHDLRYAIDP+ L +EL W P + DFE G
Sbjct  242  NGEKDNKTVVELILTLMGEDADAYDRVPDRLGHDLRYAIDPTKLREELGWQPGYGDFEHG  301

Query  301  LRTTIDWYRDNESWWRPLKDATEARYQERGQ  331
            L  TI+WYR +E WW P K+ATEA Y   GQ
Sbjct  302  LAATIEWYRTHEDWWTPAKEATEAFYARIGQ  332


>gi|125625378|dbj|BAF46773.1| Putative dTDP-glucose-4,6-dehydratase [Nocardia brasiliensis]
Length=357

 Score =  471 bits (1211),  Expect = 9e-131, Method: Compositional matrix adjust.
 Identities = 230/331 (70%), Positives = 263/331 (80%), Gaps = 1/331 (0%)

Query  1    MRLLVTGGAGFIGTNFVHSAVREHPDDAVTVLDALTYAGRRESLADVEDAIRLVQGDITD  60
            +RLLVTGGAGFIG NFVH  V E PD  V VLDALTYAG R SL  V D I  V GD+ D
Sbjct  25   VRLLVTGGAGFIGANFVHQTVTERPDTRVVVLDALTYAGNRASLDPVADRIDFVHGDVAD  84

Query  61   AELVSQLVAESDAVVHFAAESHVDNALDNPEPFLHTNVIGTFTILEAVRRHGVRLHHIST  120
            AELV++LVA++DAVVHFAAESH DN+L  P PF+ TN++GTF +L+AVR H VR HHIST
Sbjct  85   AELVNRLVADADAVVHFAAESHNDNSLAQPWPFVQTNIVGTFALLQAVREHDVRYHHIST  144

Query  121  DEVYGDLELDDRARFTESTPYNPSSPYSATKAGADMLVRAWVRSYGVRATISNCSNNYGP  180
            DEVYGDLE DD A FTE+TPYNPSSPYSA+KA +D+LVRAWVRS+GVRATISNCSNNYGP
Sbjct  145  DEVYGDLEPDDPA-FTETTPYNPSSPYSASKASSDLLVRAWVRSFGVRATISNCSNNYGP  203

Query  181  YQHVEKFIPRQITNVLTGRRPKLYGAGANVRDWIHVDDHNSAVRRILDRGRIGRTYLISS  240
            YQHVEKFIPRQITN++ G RP+LYGAG  +RDWIHVDDHN AV  +L+RGRIG+TYLI +
Sbjct  204  YQHVEKFIPRQITNLIDGVRPRLYGAGHQIRDWIHVDDHNRAVWAVLERGRIGQTYLIGA  263

Query  241  EGERDNLTVLRTLLRLMDRDPDDFDHVTDRVGHDLRYAIDPSTLYDELCWAPKHTDFEEG  300
             GE DN +V++ LL    R  DDFDHVTDR GHD RYAIDP+ L  EL W P++ DF  G
Sbjct  264  NGELDNKSVVQQLLAEFGRPTDDFDHVTDRPGHDQRYAIDPTLLRTELGWEPRYRDFRAG  323

Query  301  LRTTIDWYRDNESWWRPLKDATEARYQERGQ  331
            L  TI WYRDNESWWRP K ATE+ Y   G+
Sbjct  324  LAATIQWYRDNESWWRPQKAATESAYVAAGE  354


>gi|313141151|ref|ZP_07803344.1| DTDP-glucose 4,6-dehydratase enzyme [Bifidobacterium bifidum 
NCIMB 41171]
 gi|313133661|gb|EFR51278.1| DTDP-glucose 4,6-dehydratase enzyme [Bifidobacterium bifidum 
NCIMB 41171]
Length=340

 Score =  470 bits (1210),  Expect = 1e-130, Method: Compositional matrix adjust.
 Identities = 221/330 (67%), Positives = 265/330 (81%), Gaps = 1/330 (0%)

Query  3    LLVTGGAGFIGTNFVHSAVREHPDDAVTVLDALTYAGRRESLADV-EDAIRLVQGDITDA  61
            ++VTGG GFIG+NFVH  V  HPD  VTVLDALTYAG   ++A + ED +  V G+I DA
Sbjct  11   IIVTGGCGFIGSNFVHYVVDNHPDVHVTVLDALTYAGNIANIAGLPEDRVEFVHGNICDA  70

Query  62   ELVSQLVAESDAVVHFAAESHVDNALDNPEPFLHTNVIGTFTILEAVRRHGVRLHHISTD  121
            EL+ ++V   DA+VH+AAESH DN++ NPEPFL TNV GTF +LEAVR++GVR HH+STD
Sbjct  71   ELLDRIVPGHDAIVHYAAESHNDNSIANPEPFLKTNVEGTFRLLEAVRKYGVRYHHVSTD  130

Query  122  EVYGDLELDDRARFTESTPYNPSSPYSATKAGADMLVRAWVRSYGVRATISNCSNNYGPY  181
            EVYGDL LDD A+FTESTPY+PSSPYS+TKA +DMLVRAW R+YG+R TISNCSNNYGPY
Sbjct  131  EVYGDLALDDPAKFTESTPYHPSSPYSSTKAASDMLVRAWTRTYGLRTTISNCSNNYGPY  190

Query  182  QHVEKFIPRQITNVLTGRRPKLYGAGANVRDWIHVDDHNSAVRRILDRGRIGRTYLISSE  241
            QHVEKFIPRQITN+L G+RPKLYG G NVRDWIH +DH+S V  IL +GRIG TYLI + 
Sbjct  191  QHVEKFIPRQITNILDGQRPKLYGKGENVRDWIHTEDHSSGVWTILTKGRIGETYLIGAN  250

Query  242  GERDNLTVLRTLLRLMDRDPDDFDHVTDRVGHDLRYAIDPSTLYDELCWAPKHTDFEEGL  301
            GE++N+TVLR +L++M RD D FD V DR GHD RYAID + L  EL W P HTDFE GL
Sbjct  251  GEKNNITVLRMILKMMGRDEDAFDWVKDRPGHDRRYAIDSTKLQTELGWRPTHTDFESGL  310

Query  302  RTTIDWYRDNESWWRPLKDATEARYQERGQ  331
            R TI+WY +N +WW P K ATEARY+++GQ
Sbjct  311  RATIEWYTENRAWWEPAKAATEARYKQQGQ  340


>gi|225352523|ref|ZP_03743546.1| hypothetical protein BIFPSEUDO_04146 [Bifidobacterium pseudocatenulatum 
DSM 20438]
 gi|225156717|gb|EEG70111.1| hypothetical protein BIFPSEUDO_04146 [Bifidobacterium pseudocatenulatum 
DSM 20438]
Length=340

 Score =  469 bits (1208),  Expect = 2e-130, Method: Compositional matrix adjust.
 Identities = 220/330 (67%), Positives = 265/330 (81%), Gaps = 1/330 (0%)

Query  3    LLVTGGAGFIGTNFVHSAVREHPDDAVTVLDALTYAGRRESLADV-EDAIRLVQGDITDA  61
            ++VTGG GFIG+NFVH  V  HPD  VTVLDALTYAG  E++A + ED +  V G+I DA
Sbjct  11   IIVTGGCGFIGSNFVHYVVDNHPDVHVTVLDALTYAGNIENIAGLPEDRVEFVHGNICDA  70

Query  62   ELVSQLVAESDAVVHFAAESHVDNALDNPEPFLHTNVIGTFTILEAVRRHGVRLHHISTD  121
            EL+ ++V   DA+VH+AAESH DN++ +PEPFL TNV GTF +LEAVRR+G+R HH+STD
Sbjct  71   ELLDRIVPGHDAIVHYAAESHNDNSIADPEPFLKTNVEGTFRLLEAVRRYGIRYHHVSTD  130

Query  122  EVYGDLELDDRARFTESTPYNPSSPYSATKAGADMLVRAWVRSYGVRATISNCSNNYGPY  181
            EVYGDL LDD A+FTE TPY+PSSPYS+TKA +DMLVRAW R+YG+RATISNCSNNYGPY
Sbjct  131  EVYGDLALDDPAKFTERTPYHPSSPYSSTKAASDMLVRAWTRTYGIRATISNCSNNYGPY  190

Query  182  QHVEKFIPRQITNVLTGRRPKLYGAGANVRDWIHVDDHNSAVRRILDRGRIGRTYLISSE  241
            QHVEKFIPRQITN+L G+RPKLYG G NVRDWIH +DH+S V  IL +GRIG TYLI + 
Sbjct  191  QHVEKFIPRQITNILDGQRPKLYGKGENVRDWIHTEDHSSGVWTILTKGRIGETYLIGAN  250

Query  242  GERDNLTVLRTLLRLMDRDPDDFDHVTDRVGHDLRYAIDPSTLYDELCWAPKHTDFEEGL  301
            GE++N+TVLR +L++M +  D FD V DR GHD RYAID + L  EL W P HTDFE GL
Sbjct  251  GEKNNITVLRMILKMMGQPEDAFDWVKDRPGHDRRYAIDSTKLRTELGWTPTHTDFESGL  310

Query  302  RTTIDWYRDNESWWRPLKDATEARYQERGQ  331
            +TTIDWY DN  WW P K ATEA+Y+++GQ
Sbjct  311  KTTIDWYTDNRQWWEPAKAATEAKYKQQGQ  340


>gi|300743860|ref|ZP_07072880.1| dTDP-glucose 4,6-dehydratase [Rothia dentocariosa M567]
 gi|300380221|gb|EFJ76784.1| dTDP-glucose 4,6-dehydratase [Rothia dentocariosa M567]
Length=332

 Score =  469 bits (1206),  Expect = 3e-130, Method: Compositional matrix adjust.
 Identities = 223/331 (68%), Positives = 269/331 (82%), Gaps = 4/331 (1%)

Query  3    LLVTGGAGFIGTNFVHSAVREHPDDAVTVLDALTYAGRRESLADVEDAIR--LVQGDITD  60
            LLVTGGAGFIG+NFVH  + ++ +  VTVLD +TYA  + SL D  D  R  L+ GDI D
Sbjct  4    LLVTGGAGFIGSNFVHYLL-DNTEHTVTVLDKMTYAANKTSL-DGLDVTRFNLIVGDIAD  61

Query  61   AELVSQLVAESDAVVHFAAESHVDNALDNPEPFLHTNVIGTFTILEAVRRHGVRLHHIST  120
             EL  +LVA++DAV+H+AAESH DN+L NPEPF+HTN++GTFT+LEAVRRHG R HHIST
Sbjct  62   RELTDELVAQADAVIHYAAESHNDNSLANPEPFIHTNLVGTFTLLEAVRRHGTRYHHIST  121

Query  121  DEVYGDLELDDRARFTESTPYNPSSPYSATKAGADMLVRAWVRSYGVRATISNCSNNYGP  180
            DEV+GDL LDD A+FTE+TPYNPSSPYS+TKAG+D+LVRAWVRS+G+ ATISNCSNNYGP
Sbjct  122  DEVFGDLALDDPAKFTETTPYNPSSPYSSTKAGSDLLVRAWVRSFGIEATISNCSNNYGP  181

Query  181  YQHVEKFIPRQITNVLTGRRPKLYGAGANVRDWIHVDDHNSAVRRILDRGRIGRTYLISS  240
            YQH+EKFIPRQITN+L+G  PKLYG G NVRDWIH  DH+SAV RIL+ G+IG TYLI +
Sbjct  182  YQHIEKFIPRQITNILSGLTPKLYGEGLNVRDWIHASDHSSAVLRILESGKIGETYLIGA  241

Query  241  EGERDNLTVLRTLLRLMDRDPDDFDHVTDRVGHDLRYAIDPSTLYDELCWAPKHTDFEEG  300
            +GE +N+TVLRT+LRLM +D +DF+HV DR GHD+RYAID + L +EL W P+ TDFE G
Sbjct  242  DGEENNITVLRTILRLMGKDENDFEHVRDRPGHDMRYAIDGTRLREELGWEPQFTDFEAG  301

Query  301  LRTTIDWYRDNESWWRPLKDATEARYQERGQ  331
            L  TI WY DN SWW PLK   EA+Y + GQ
Sbjct  302  LADTIAWYTDNRSWWEPLKAEVEAKYAKAGQ  332


>gi|310286572|ref|YP_003937830.1| dTDP-glucose 4,6-dehydratase involved rhamnose biosynthesis [Bifidobacterium 
bifidum S17]
 gi|309250508|gb|ADO52256.1| dTDP-glucose 4,6-dehydratase involved rhamnose biosynthesis [Bifidobacterium 
bifidum S17]
Length=340

 Score =  469 bits (1206),  Expect = 3e-130, Method: Compositional matrix adjust.
 Identities = 222/330 (68%), Positives = 264/330 (80%), Gaps = 1/330 (0%)

Query  3    LLVTGGAGFIGTNFVHSAVREHPDDAVTVLDALTYAGRRESLADV-EDAIRLVQGDITDA  61
            ++VTGG GFIG+NFVH  V  HPD  VTVLDALTYAG   ++A + ED +  V G+I DA
Sbjct  11   IIVTGGCGFIGSNFVHYVVDNHPDVHVTVLDALTYAGNIANIAGLPEDRVEFVHGNICDA  70

Query  62   ELVSQLVAESDAVVHFAAESHVDNALDNPEPFLHTNVIGTFTILEAVRRHGVRLHHISTD  121
            EL+ ++V   DA+VH+AAESH DN++ NPEPFL TNV GTF +LEAVR++GVR HH+STD
Sbjct  71   ELLDRIVPGHDAIVHYAAESHNDNSIANPEPFLKTNVEGTFRLLEAVRKYGVRYHHVSTD  130

Query  122  EVYGDLELDDRARFTESTPYNPSSPYSATKAGADMLVRAWVRSYGVRATISNCSNNYGPY  181
            EVYGDL LDD A+FTESTPY+PSSPYS+TKA +DMLVRAW R+YG+R TISNCSNNYGPY
Sbjct  131  EVYGDLALDDPAKFTESTPYHPSSPYSSTKAASDMLVRAWTRTYGLRTTISNCSNNYGPY  190

Query  182  QHVEKFIPRQITNVLTGRRPKLYGAGANVRDWIHVDDHNSAVRRILDRGRIGRTYLISSE  241
            QHVEKFIPRQITN+L G RPKLYG G NVRDWIH +DH+S V  IL RGRIG TYLI + 
Sbjct  191  QHVEKFIPRQITNILEGIRPKLYGKGENVRDWIHTEDHSSGVWTILTRGRIGETYLIGAN  250

Query  242  GERDNLTVLRTLLRLMDRDPDDFDHVTDRVGHDLRYAIDPSTLYDELCWAPKHTDFEEGL  301
            GER+N+TVLR +L++M +D D FD V DR GHD RYAID + L  EL W P HTDFE GL
Sbjct  251  GERNNITVLRMILKMMGQDEDAFDWVKDRPGHDRRYAIDSTKLQTELGWRPTHTDFESGL  310

Query  302  RTTIDWYRDNESWWRPLKDATEARYQERGQ  331
            R TI+WY +N +WW P K ATEARY+++GQ
Sbjct  311  RATIEWYTENRAWWEPAKAATEARYKQQGQ  340


>gi|311113105|ref|YP_003984327.1| dTDP-glucose 4,6-dehydratase [Rothia dentocariosa ATCC 17931]
 gi|310944599|gb|ADP40893.1| dTDP-glucose 4,6-dehydratase [Rothia dentocariosa ATCC 17931]
Length=332

 Score =  469 bits (1206),  Expect = 4e-130, Method: Compositional matrix adjust.
 Identities = 219/330 (67%), Positives = 268/330 (82%), Gaps = 2/330 (0%)

Query  3    LLVTGGAGFIGTNFVHSAVREHPDDAVTVLDALTYAGRRESLADVEDA-IRLVQGDITDA  61
            LLVTGGAGFIG+NFVH  + ++ +  VTVLD +TYA  + SL  ++     L+ GDI D 
Sbjct  4    LLVTGGAGFIGSNFVHYLL-DNTEHTVTVLDKMTYAANKTSLNGLDGTRFNLMVGDIADR  62

Query  62   ELVSQLVAESDAVVHFAAESHVDNALDNPEPFLHTNVIGTFTILEAVRRHGVRLHHISTD  121
            EL  +LVA++DAV+H+AAESH DN+L NPEPF+HTN++GTFT+LEAVRRHG R HHISTD
Sbjct  63   ELTDELVAQADAVIHYAAESHNDNSLANPEPFIHTNLVGTFTLLEAVRRHGTRYHHISTD  122

Query  122  EVYGDLELDDRARFTESTPYNPSSPYSATKAGADMLVRAWVRSYGVRATISNCSNNYGPY  181
            EV+GDL L+D A+FTE+TPYNPSSPYS+TKAG+D+LVRAWVRS+G+ ATISNCSNNYGPY
Sbjct  123  EVFGDLALEDPAKFTETTPYNPSSPYSSTKAGSDLLVRAWVRSFGIEATISNCSNNYGPY  182

Query  182  QHVEKFIPRQITNVLTGRRPKLYGAGANVRDWIHVDDHNSAVRRILDRGRIGRTYLISSE  241
            QH+EKFIPRQITN+L+G  PKLYG G NVRDWIH  DH+SAV RIL+ G+IG TYLI ++
Sbjct  183  QHIEKFIPRQITNILSGLTPKLYGEGLNVRDWIHASDHSSAVLRILESGKIGETYLIGAD  242

Query  242  GERDNLTVLRTLLRLMDRDPDDFDHVTDRVGHDLRYAIDPSTLYDELCWAPKHTDFEEGL  301
            GE +N+TVLRT+LRLM +D +DF+HV DR GHD+RYAID + L +EL W P+ TDFE GL
Sbjct  243  GEENNITVLRTILRLMGKDENDFEHVIDRPGHDMRYAIDGTRLREELGWEPQFTDFEAGL  302

Query  302  RTTIDWYRDNESWWRPLKDATEARYQERGQ  331
              TI WY DN SWW PLK   EA+Y + GQ
Sbjct  303  ADTIAWYTDNRSWWEPLKAEVEAKYAKAGQ  332


>gi|296130221|ref|YP_003637471.1| dTDP-glucose 4,6-dehydratase [Cellulomonas flavigena DSM 20109]
 gi|296022036|gb|ADG75272.1| dTDP-glucose 4,6-dehydratase [Cellulomonas flavigena DSM 20109]
Length=331

 Score =  467 bits (1202),  Expect = 9e-130, Method: Compositional matrix adjust.
 Identities = 224/331 (68%), Positives = 267/331 (81%), Gaps = 0/331 (0%)

Query  1    MRLLVTGGAGFIGTNFVHSAVREHPDDAVTVLDALTYAGRRESLADVEDAIRLVQGDITD  60
            MR+LVTGGAGFIG+NFVH  VRE PD  VTVLDALTYAG   SL  V+  + L +GD+ D
Sbjct  1    MRMLVTGGAGFIGSNFVHQTVRERPDVHVTVLDALTYAGDERSLDPVDGRVVLAKGDVAD  60

Query  61   AELVSQLVAESDAVVHFAAESHVDNALDNPEPFLHTNVIGTFTILEAVRRHGVRLHHIST  120
             ++V +LV ++D VVHFAAESH DN+L +P PF+ TNVIGT+ +LEAVRR+ VR HH+ST
Sbjct  61   PDIVDRLVKDADLVVHFAAESHNDNSLHDPWPFVRTNVIGTYQLLEAVRRYDVRYHHVST  120

Query  121  DEVYGDLELDDRARFTESTPYNPSSPYSATKAGADMLVRAWVRSYGVRATISNCSNNYGP  180
            DEVYGDLELDD A+FT  TPYNPSSPYS+TKA +D+LVRAW RS+GVRATISNCSNNYGP
Sbjct  121  DEVYGDLELDDPAKFTPETPYNPSSPYSSTKASSDLLVRAWARSFGVRATISNCSNNYGP  180

Query  181  YQHVEKFIPRQITNVLTGRRPKLYGAGANVRDWIHVDDHNSAVRRILDRGRIGRTYLISS  240
            YQHVEKFIPRQITNV+ G RPKLYG G NVRDWIHV+DHNSAV RI++ GR+G TYLI +
Sbjct  181  YQHVEKFIPRQITNVVDGVRPKLYGTGENVRDWIHVEDHNSAVWRIIEDGRLGETYLIGA  240

Query  241  EGERDNLTVLRTLLRLMDRDPDDFDHVTDRVGHDLRYAIDPSTLYDELCWAPKHTDFEEG  300
            +GE+DN TV+  +L LM +  D +DHV DR GHDLRYAID + L  EL W P++T F +G
Sbjct  241  DGEKDNRTVIELILELMGQPSDAYDHVNDRPGHDLRYAIDATKLRTELGWEPRYTTFADG  300

Query  301  LRTTIDWYRDNESWWRPLKDATEARYQERGQ  331
            L  TI+WYR NE+WWRP KDATEA+Y   G+
Sbjct  301  LAATIEWYRANEAWWRPQKDATEAKYAVLGR  331


>gi|289704884|ref|ZP_06501301.1| dTDP-glucose 4,6-dehydratase [Micrococcus luteus SK58]
 gi|289558380|gb|EFD51654.1| dTDP-glucose 4,6-dehydratase [Micrococcus luteus SK58]
Length=331

 Score =  467 bits (1201),  Expect = 1e-129, Method: Compositional matrix adjust.
 Identities = 226/332 (69%), Positives = 267/332 (81%), Gaps = 2/332 (0%)

Query  1    MRLLVTGGAGFIGTNFVHSAVREHPDDAVTVLDALTYAGRRESLADV-EDAIRLVQGDIT  59
            M LLVTGGAGFIG+NFVH  VRE   D V VLD LTYAG RE+LA + ED + L  GDI 
Sbjct  1    MHLLVTGGAGFIGSNFVHHVVRETGHD-VVVLDKLTYAGNRENLAGLPEDRVTLEVGDIC  59

Query  60   DAELVSQLVAESDAVVHFAAESHVDNALDNPEPFLHTNVIGTFTILEAVRRHGVRLHHIS  119
            D  LV +LVAESDAVVH+AAESH DN+L++P PF+ TN++GTF +LEAVR+HG R HH+S
Sbjct  60   DTALVDRLVAESDAVVHYAAESHNDNSLNDPSPFIQTNIVGTFVLLEAVRKHGKRFHHVS  119

Query  120  TDEVYGDLELDDRARFTESTPYNPSSPYSATKAGADMLVRAWVRSYGVRATISNCSNNYG  179
            TDEVYGDLELDD A+FTE+TPYNPSSPYSA+KAG+D LVRAWVRS+GV+AT+SNCSNNYG
Sbjct  120  TDEVYGDLELDDPAKFTETTPYNPSSPYSASKAGSDHLVRAWVRSFGVQATLSNCSNNYG  179

Query  180  PYQHVEKFIPRQITNVLTGRRPKLYGAGANVRDWIHVDDHNSAVRRILDRGRIGRTYLIS  239
            PYQH+EKFIPRQITN++ G RP+LYG G NVRDWIH +DH+SAV RIL+RG IGRTYLI 
Sbjct  180  PYQHIEKFIPRQITNLIDGVRPRLYGQGVNVRDWIHTEDHSSAVLRILERGEIGRTYLIG  239

Query  240  SEGERDNLTVLRTLLRLMDRDPDDFDHVTDRVGHDLRYAIDPSTLYDELCWAPKHTDFEE  299
            S+GER+N  ++  LL L DR  DD+D V DR GHDLRYAID + L  EL W P+ TD   
Sbjct  240  SDGERNNREIVEILLELFDRPADDYDLVADRPGHDLRYAIDNTALRTELGWEPQFTDIRA  299

Query  300  GLRTTIDWYRDNESWWRPLKDATEARYQERGQ  331
            GL  T+ WYR+NE+WWRP K A EA Y+ +GQ
Sbjct  300  GLADTVRWYRENEAWWRPAKAAVEATYRAQGQ  331


>gi|139439924|ref|ZP_01773276.1| Hypothetical protein COLAER_02314 [Collinsella aerofaciens ATCC 
25986]
 gi|133774774|gb|EBA38594.1| Hypothetical protein COLAER_02314 [Collinsella aerofaciens ATCC 
25986]
Length=339

 Score =  467 bits (1201),  Expect = 1e-129, Method: Compositional matrix adjust.
 Identities = 222/330 (68%), Positives = 265/330 (81%), Gaps = 1/330 (0%)

Query  3    LLVTGGAGFIGTNFVHSAVREHPDDAVTVLDALTYAGRRESLADV-EDAIRLVQGDITDA  61
            ++VTGG GFIG+NFVH  V  HPD  VTVLD LTYAG  E++A + ED + LV GDI DA
Sbjct  10   IIVTGGCGFIGSNFVHYVVNNHPDVHVTVLDKLTYAGNPENIAGLPEDRVELVVGDICDA  69

Query  62   ELVSQLVAESDAVVHFAAESHVDNALDNPEPFLHTNVIGTFTILEAVRRHGVRLHHISTD  121
             L+ ++V   DA+VH+AAESH DN++ +PEPFL TNV GTF +LEAVR++G+R HH+STD
Sbjct  70   GLLDRIVPGHDAIVHYAAESHNDNSIADPEPFLRTNVEGTFRLLEAVRKYGIRYHHVSTD  129

Query  122  EVYGDLELDDRARFTESTPYNPSSPYSATKAGADMLVRAWVRSYGVRATISNCSNNYGPY  181
            EVYGDL LDD A+FTE TPY PSSPYS+TKA +DMLVRAW R+YG+R TISNCSNNYGPY
Sbjct  130  EVYGDLALDDPAKFTEETPYKPSSPYSSTKASSDMLVRAWTRTYGLRTTISNCSNNYGPY  189

Query  182  QHVEKFIPRQITNVLTGRRPKLYGAGANVRDWIHVDDHNSAVRRILDRGRIGRTYLISSE  241
            QHVEKFIPRQITN++ G RPKLYG G NVRDWIH +DH+SAV  IL +GR+G TYLI ++
Sbjct  190  QHVEKFIPRQITNIVDGVRPKLYGRGENVRDWIHTEDHSSAVWDILTKGRMGETYLIGAD  249

Query  242  GERDNLTVLRTLLRLMDRDPDDFDHVTDRVGHDLRYAIDPSTLYDELCWAPKHTDFEEGL  301
            GER+N+TVLR +L  M +DP+DFD V DR GHD RYAID + L  EL W P HTDF EGL
Sbjct  250  GERNNITVLRMILEAMGKDPEDFDWVADRPGHDRRYAIDSTKLQRELGWRPAHTDFAEGL  309

Query  302  RTTIDWYRDNESWWRPLKDATEARYQERGQ  331
            + TIDWY  NESWWRP K+ATEARY+ +GQ
Sbjct  310  KATIDWYVANESWWRPAKEATEARYRAQGQ  339


>gi|116671225|ref|YP_832158.1| dTDP-glucose 4,6-dehydratase [Arthrobacter sp. FB24]
 gi|116611334|gb|ABK04058.1| dTDP-glucose 4,6-dehydratase [Arthrobacter sp. FB24]
Length=332

 Score =  467 bits (1201),  Expect = 1e-129, Method: Compositional matrix adjust.
 Identities = 221/332 (67%), Positives = 269/332 (82%), Gaps = 2/332 (0%)

Query  1    MRLLVTGGAGFIGTNFVHSAVREHPDDAVTVLDALTYAGRRESLADV-EDAIRLVQGDIT  59
             +LLVTGGAGFIG+NFVH  V E+ DD VTVLD LTYAG  ESL+ + E+  R VQGDI 
Sbjct  2    QKLLVTGGAGFIGSNFVHY-VLENTDDHVTVLDKLTYAGNLESLSGLPEERFRFVQGDIC  60

Query  60   DAELVSQLVAESDAVVHFAAESHVDNALDNPEPFLHTNVIGTFTILEAVRRHGVRLHHIS  119
            DA LV  LVA++D VVH+AAESH DN+L +P PFL TN+IGT+T++EA R+H  R HHIS
Sbjct  61   DAALVDTLVADADVVVHYAAESHNDNSLHDPRPFLDTNIIGTYTLIEAARKHNKRFHHIS  120

Query  120  TDEVYGDLELDDRARFTESTPYNPSSPYSATKAGADMLVRAWVRSYGVRATISNCSNNYG  179
            TDEVYGDLELDD  RFTE TPYNPSSPYS+TKAG+D+LVRAWVRS+G++ATISNCSNNYG
Sbjct  121  TDEVYGDLELDDPERFTEETPYNPSSPYSSTKAGSDLLVRAWVRSFGLQATISNCSNNYG  180

Query  180  PYQHVEKFIPRQITNVLTGRRPKLYGAGANVRDWIHVDDHNSAVRRILDRGRIGRTYLIS  239
            PYQHVEKFIPRQITNV+ G RPKLYG G NVRDWIH +DH+SAV  I+ +G+IG TYLI 
Sbjct  181  PYQHVEKFIPRQITNVIDGIRPKLYGKGENVRDWIHANDHSSAVLAIIAKGKIGETYLIG  240

Query  240  SEGERDNLTVLRTLLRLMDRDPDDFDHVTDRVGHDLRYAIDPSTLYDELCWAPKHTDFEE  299
            ++GE++N  V+  +L+ M + PD +DHV DR GHDLRYAID + L +EL W PK ++F+ 
Sbjct  241  ADGEKNNKDVVELILKHMGQSPDAYDHVVDRPGHDLRYAIDSTKLRNELGWEPKFSNFDA  300

Query  300  GLRTTIDWYRDNESWWRPLKDATEARYQERGQ  331
            G+  TI WYR+NE+WWRP K  TEA+Y+E+GQ
Sbjct  301  GIEDTIAWYRENENWWRPQKAQTEAKYKEQGQ  332


>gi|119026525|ref|YP_910370.1| rhamnose biosynthesis dTDP-glucose 4,6-dehydratase [Bifidobacterium 
adolescentis ATCC 15703]
 gi|118766109|dbj|BAF40288.1| DTDP-glucose 4,6-dehydratase enzyme involved in rhamnose biosynthesis 
[Bifidobacterium adolescentis ATCC 15703]
Length=340

 Score =  465 bits (1197),  Expect = 4e-129, Method: Compositional matrix adjust.
 Identities = 217/330 (66%), Positives = 264/330 (80%), Gaps = 1/330 (0%)

Query  3    LLVTGGAGFIGTNFVHSAVREHPDDAVTVLDALTYAGRRESLADV-EDAIRLVQGDITDA  61
            ++VTGG GFIG+NFVH  V  HPD  VTVLD LTYAG  E++A + ED + LV GDI DA
Sbjct  11   IIVTGGCGFIGSNFVHYVVNNHPDVHVTVLDKLTYAGNPENIAGLPEDRVELVVGDICDA  70

Query  62   ELVSQLVAESDAVVHFAAESHVDNALDNPEPFLHTNVIGTFTILEAVRRHGVRLHHISTD  121
            +L+ ++V   DA+VH+AAESH DN++ NPEPFL TNV GTF +LEAVR++G+R HH+STD
Sbjct  71   DLLDKIVPGHDAIVHYAAESHNDNSIANPEPFLKTNVEGTFRLLEAVRKYGIRYHHVSTD  130

Query  122  EVYGDLELDDRARFTESTPYNPSSPYSATKAGADMLVRAWVRSYGVRATISNCSNNYGPY  181
            EVYGDL LDD A+FTE TPY+PSSPYS+TKA +DMLVRAW R+YG+RATISNCSNNYGP+
Sbjct  131  EVYGDLALDDPAKFTEHTPYHPSSPYSSTKAASDMLVRAWTRTYGIRATISNCSNNYGPF  190

Query  182  QHVEKFIPRQITNVLTGRRPKLYGAGANVRDWIHVDDHNSAVRRILDRGRIGRTYLISSE  241
            QHVEKFIPRQITN+L G+RPKLYG G NVRDWIH +DH+S V  IL +GRIG TYLI + 
Sbjct  191  QHVEKFIPRQITNILDGQRPKLYGKGENVRDWIHTEDHSSGVWTILTKGRIGETYLIGAN  250

Query  242  GERDNLTVLRTLLRLMDRDPDDFDHVTDRVGHDLRYAIDPSTLYDELCWAPKHTDFEEGL  301
            GE++N+TVLR +L++M +  D FD V DR GHD RYAID + L  EL W P+HTDFE GL
Sbjct  251  GEKNNITVLRMILKMMGQPEDAFDWVKDRPGHDRRYAIDSTKLRTELGWTPRHTDFESGL  310

Query  302  RTTIDWYRDNESWWRPLKDATEARYQERGQ  331
              TI+WY  N +WW P K ATEARY+++GQ
Sbjct  311  AQTIEWYTQNRAWWEPAKAATEARYKQQGQ  340


>gi|319949394|ref|ZP_08023460.1| dTDP-glucose 4,6-dehydratase [Dietzia cinnamea P4]
 gi|319436941|gb|EFV91995.1| dTDP-glucose 4,6-dehydratase [Dietzia cinnamea P4]
Length=342

 Score =  465 bits (1196),  Expect = 5e-129, Method: Compositional matrix adjust.
 Identities = 230/336 (69%), Positives = 265/336 (79%), Gaps = 11/336 (3%)

Query  1    MRLLVTGGAGFIGTNFVHSAVREHPDDAVTVLDALTYAGRRESLADV-EDAIRLVQGDIT  59
            MRL+VTGGAGFIG NFV S VRE+P   VTVLD++TYA  R +L  +  D +RLV+ D  
Sbjct  1    MRLVVTGGAGFIGANFVRSVVREYPQAHVTVLDSMTYAANRANLDGLPADRVRLVEADCA  60

Query  60   DA----ELVSQLVAESDAVVHFAAESHVDNALDNPEPFLHTNVIGTFTILEAVRRHGVRL  115
            DA     LVS+L    DAVVHFAAESH DN+L  P PF+H+N++GT+TILEA RRH VRL
Sbjct  61   DAAITDRLVSELTGRRDAVVHFAAESHNDNSLATPWPFVHSNIVGTYTILEACRRHDVRL  120

Query  116  HHISTDEVYGDLELDDRARFTESTPYNPSSPYSATKAGADMLVRAWVRSYGVRATISNCS  175
            HH+STDEVYGDLELDD A FT +T YNPSSPYSATKAGADMLVRAWVRS+GVRATISNCS
Sbjct  121  HHVSTDEVYGDLELDDPATFTPATAYNPSSPYSATKAGADMLVRAWVRSFGVRATISNCS  180

Query  176  NNYGPYQHVEKFIPRQITNVLTGRRPKLYGAGANVRDWIHVDDHNSAVRRILDRGRIGRT  235
            NNYGPYQHVEKFIPRQITN+L GRRP+LYG+GANVRDWIHVDDHNSAV R+L+ G +GRT
Sbjct  181  NNYGPYQHVEKFIPRQITNILDGRRPRLYGSGANVRDWIHVDDHNSAVLRVLEAGELGRT  240

Query  236  YLISSEGERDNLTVLRTLLRLM-----DRDPDDFDHVTDRVGHDLRYAIDPSTLYDELCW  290
            YLI ++GER NL V+R +  LM       DP  FDHVTDR GHDLRYAID S   DEL W
Sbjct  241  YLIGADGERSNLEVMRMICELMGVSGTGGDP-GFDHVTDRPGHDLRYAIDASATRDELGW  299

Query  291  APKHTDFEEGLRTTIDWYRDNESWWRPLKDATEARY  326
             P+HTDF EGLR T++WY  +  WW P+K+  EA+Y
Sbjct  300  EPQHTDFREGLRQTVEWYAAHRDWWEPIKERVEAKY  335



Lambda     K      H
   0.319    0.136    0.415 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Effective search space used: 589755449788


  Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
    Posted date:  Sep 5, 2011  4:36 AM
  Number of letters in database: 5,219,829,388
  Number of sequences in database:  15,229,318



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40