BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv3470c Length=552 Score E Sequences producing significant alignments: (Bits) Value gi|308406166|ref|ZP_07669531.1| acetolactate synthase large subu... 1090 0.0 gi|167969811|ref|ZP_02552088.1| acetolactate synthase large subu... 1090 0.0 gi|15610606|ref|NP_217987.1| acetolactate synthase large subunit... 1089 0.0 gi|31794646|ref|NP_857139.1| acetolactate synthase large subunit... 1087 0.0 gi|339633475|ref|YP_004725117.1| acetolactate synthase (large su... 1085 0.0 gi|340628440|ref|YP_004746892.1| putative acetolactate synthase ... 1074 0.0 gi|15843082|ref|NP_338119.1| acetolactate synthase, large subuni... 1071 0.0 gi|289576206|ref|ZP_06456433.1| acetolactate synthase large subu... 718 0.0 gi|189424179|ref|YP_001951356.1| thiamine pyrophosphate protein ... 251 2e-64 gi|298243379|ref|ZP_06967186.1| thiamine pyrophosphate protein T... 229 8e-58 gi|334338960|ref|YP_004543940.1| acetolactate synthase large sub... 223 7e-56 gi|308274605|emb|CBX31204.1| hypothetical protein N47_E47160 [un... 218 2e-54 gi|307150286|ref|YP_003885670.1| acetolactate synthase large sub... 218 3e-54 gi|75908969|ref|YP_323265.1| acetolactate synthase 3 catalytic s... 215 2e-53 gi|298247788|ref|ZP_06971593.1| thiamine pyrophosphate protein T... 214 3e-53 gi|20093969|ref|NP_613816.1| acetolactate synthase catalytic sub... 214 3e-53 gi|291569589|dbj|BAI91861.1| acetolactate synthase [Arthrospira ... 214 4e-53 gi|124485430|ref|YP_001030046.1| acetolactate synthase, large su... 213 7e-53 gi|167045506|gb|ABZ10159.1| putative Thiamine pyrophosphate enzy... 213 8e-53 gi|11467754|ref|NP_050806.1| acetohydroxyacid synthase large sub... 212 2e-52 gi|330506659|ref|YP_004383087.1| acetolactate synthase, large su... 211 2e-52 gi|282900124|ref|ZP_06308081.1| Acetolactate synthase, large sub... 210 6e-52 gi|119509049|ref|ZP_01628200.1| acetolactate synthase III large ... 210 6e-52 gi|300865814|ref|ZP_07110564.1| acetolactate synthase 3 catalyti... 210 6e-52 gi|225181135|ref|ZP_03734581.1| acetolactate synthase, large sub... 210 7e-52 gi|150391156|ref|YP_001321205.1| acetolactate synthase, large su... 209 9e-52 gi|218441880|ref|YP_002380209.1| acetolactate synthase 3 catalyt... 209 1e-51 gi|282896701|ref|ZP_06304709.1| Acetolactate synthase, large sub... 209 1e-51 gi|186682147|ref|YP_001865343.1| acetolactate synthase 3 catalyt... 208 2e-51 gi|209523765|ref|ZP_03272318.1| acetolactate synthase, large sub... 208 2e-51 gi|332710392|ref|ZP_08430340.1| acetolactate synthase, large sub... 208 2e-51 gi|83645355|ref|YP_433790.1| thiamine pyrophosphate-requiring en... 207 4e-51 gi|148262699|ref|YP_001229405.1| acetolactate synthase, large su... 207 5e-51 gi|283853803|ref|ZP_06371026.1| thiamine pyrophosphate protein d... 206 1e-50 gi|254433415|ref|ZP_05046923.1| Thiamine pyrophosphate enzyme, c... 206 1e-50 gi|77164772|ref|YP_343297.1| acetolactate synthase large subunit... 205 1e-50 gi|56478123|ref|YP_159712.1| acetolactate synthase catalytic sub... 205 2e-50 gi|332704423|ref|ZP_08424511.1| acetolactate synthase, large sub... 205 2e-50 gi|81298950|ref|YP_399158.1| acetolactate synthase 3 catalytic s... 205 2e-50 gi|91202797|emb|CAJ72436.1| strongly similar to acetohydroxy aci... 204 2e-50 gi|152905|gb|AAA26594.1| acetohydroxy acid synthase (AHAS) [Arth... 204 3e-50 gi|56751375|ref|YP_172076.1| acetolactate synthase 3 catalytic s... 204 3e-50 gi|118580972|ref|YP_902222.1| thiamine pyrophosphate binding dom... 204 4e-50 gi|126660706|ref|ZP_01731805.1| acetolactate synthase III large ... 204 4e-50 gi|84488856|ref|YP_447088.1| IlvB1 [Methanosphaera stadtmanae DS... 203 6e-50 gi|253689985|ref|YP_003019175.1| acetolactate synthase, large su... 203 7e-50 gi|16330569|ref|NP_441297.1| acetolactate synthase 3 catalytic s... 203 7e-50 gi|307719394|ref|YP_003874926.1| acetolactate synthase large sub... 202 1e-49 gi|317487960|ref|ZP_07946544.1| acetolactate synthase [Eggerthel... 201 2e-49 gi|339412483|gb|AEJ62048.1| acetolactate synthase, large subunit... 201 2e-49 >gi|308406166|ref|ZP_07669531.1| acetolactate synthase large subunit ilvB2 [Mycobacterium tuberculosis SUMu012] gi|308364298|gb|EFP53149.1| acetolactate synthase large subunit ilvB2 [Mycobacterium tuberculosis SUMu012] gi|339296290|gb|AEJ48401.1| acetolactate synthase large subunit ilvB2 [Mycobacterium tuberculosis CCDC5079] Length=555 Score = 1090 bits (2819), Expect = 0.0, Method: Compositional matrix adjust. Identities = 552/552 (100%), Positives = 552/552 (100%), Gaps = 0/552 (0%) Query 1 VTVGDHLVARMRAAGISVVCGLPTSRLDSLLVRLSRDAGFQIVLARHEGGAGYLADGFAR 60 VTVGDHLVARMRAAGISVVCGLPTSRLDSLLVRLSRDAGFQIVLARHEGGAGYLADGFAR Sbjct 4 VTVGDHLVARMRAAGISVVCGLPTSRLDSLLVRLSRDAGFQIVLARHEGGAGYLADGFAR 63 Query 61 ASGKSAAVFVAGPGATNVISAVANASVNQVPMLILTGEVAVGEFGLHSQQDTSDDGLGLG 120 ASGKSAAVFVAGPGATNVISAVANASVNQVPMLILTGEVAVGEFGLHSQQDTSDDGLGLG Sbjct 64 ASGKSAAVFVAGPGATNVISAVANASVNQVPMLILTGEVAVGEFGLHSQQDTSDDGLGLG 123 Query 121 ATFRRFCRCSVSIESIANARSKIDSAFRALASIPRGPVHIALPRDLVDERLPAHQLGTAA 180 ATFRRFCRCSVSIESIANARSKIDSAFRALASIPRGPVHIALPRDLVDERLPAHQLGTAA Sbjct 124 ATFRRFCRCSVSIESIANARSKIDSAFRALASIPRGPVHIALPRDLVDERLPAHQLGTAA 183 Query 181 AGLGGLRTLAPCGPDVADEVIGRLDRSRAPMLVLGNGCRLDGIGEQIVAFCEKAGLPFAT 240 AGLGGLRTLAPCGPDVADEVIGRLDRSRAPMLVLGNGCRLDGIGEQIVAFCEKAGLPFAT Sbjct 184 AGLGGLRTLAPCGPDVADEVIGRLDRSRAPMLVLGNGCRLDGIGEQIVAFCEKAGLPFAT 243 Query 241 TPNGRGIVAETHPLSLGVLGIFGDGRADEYLFDTPCDLLIAVGVSFGGLVTRSFSPRWRG 300 TPNGRGIVAETHPLSLGVLGIFGDGRADEYLFDTPCDLLIAVGVSFGGLVTRSFSPRWRG Sbjct 244 TPNGRGIVAETHPLSLGVLGIFGDGRADEYLFDTPCDLLIAVGVSFGGLVTRSFSPRWRG 303 Query 301 LKADVVHVDPDPSAVGRFVATSLGITTSGRAFVNALNCGRPPRFCRRVGVRPPAPAALPG 360 LKADVVHVDPDPSAVGRFVATSLGITTSGRAFVNALNCGRPPRFCRRVGVRPPAPAALPG Sbjct 304 LKADVVHVDPDPSAVGRFVATSLGITTSGRAFVNALNCGRPPRFCRRVGVRPPAPAALPG 363 Query 361 TPQARGESIHPLELMHELDRELAPNATICADVGTCISWTFRGIPVRRPGRFFATVDFSPM 420 TPQARGESIHPLELMHELDRELAPNATICADVGTCISWTFRGIPVRRPGRFFATVDFSPM Sbjct 364 TPQARGESIHPLELMHELDRELAPNATICADVGTCISWTFRGIPVRRPGRFFATVDFSPM 423 Query 421 GCGIAGAIGVALARPEEHVICIAGDGAFLMHGTEISTAVAHGIRVTWAVLNDGQMSASAG 480 GCGIAGAIGVALARPEEHVICIAGDGAFLMHGTEISTAVAHGIRVTWAVLNDGQMSASAG Sbjct 424 GCGIAGAIGVALARPEEHVICIAGDGAFLMHGTEISTAVAHGIRVTWAVLNDGQMSASAG 483 Query 481 PVSGRMDPSPVARIGANDLAAMARALGAEGIRVDTRCELRAGVQKALAATGPCVLDIAID 540 PVSGRMDPSPVARIGANDLAAMARALGAEGIRVDTRCELRAGVQKALAATGPCVLDIAID Sbjct 484 PVSGRMDPSPVARIGANDLAAMARALGAEGIRVDTRCELRAGVQKALAATGPCVLDIAID 543 Query 541 PEINKPDIGLGR 552 PEINKPDIGLGR Sbjct 544 PEINKPDIGLGR 555 >gi|167969811|ref|ZP_02552088.1| acetolactate synthase large subunit ilvB2 [Mycobacterium tuberculosis H37Ra] gi|253800515|ref|YP_003033516.1| acetolactate synthase large subunit ilvB2 [Mycobacterium tuberculosis KZN 1435] gi|254234059|ref|ZP_04927384.1| acetolactate synthase (large subunit) ilvB2 [Mycobacterium tuberculosis C] 26 more sequence titles Length=557 Score = 1090 bits (2818), Expect = 0.0, Method: Compositional matrix adjust. Identities = 552/552 (100%), Positives = 552/552 (100%), Gaps = 0/552 (0%) Query 1 VTVGDHLVARMRAAGISVVCGLPTSRLDSLLVRLSRDAGFQIVLARHEGGAGYLADGFAR 60 VTVGDHLVARMRAAGISVVCGLPTSRLDSLLVRLSRDAGFQIVLARHEGGAGYLADGFAR Sbjct 6 VTVGDHLVARMRAAGISVVCGLPTSRLDSLLVRLSRDAGFQIVLARHEGGAGYLADGFAR 65 Query 61 ASGKSAAVFVAGPGATNVISAVANASVNQVPMLILTGEVAVGEFGLHSQQDTSDDGLGLG 120 ASGKSAAVFVAGPGATNVISAVANASVNQVPMLILTGEVAVGEFGLHSQQDTSDDGLGLG Sbjct 66 ASGKSAAVFVAGPGATNVISAVANASVNQVPMLILTGEVAVGEFGLHSQQDTSDDGLGLG 125 Query 121 ATFRRFCRCSVSIESIANARSKIDSAFRALASIPRGPVHIALPRDLVDERLPAHQLGTAA 180 ATFRRFCRCSVSIESIANARSKIDSAFRALASIPRGPVHIALPRDLVDERLPAHQLGTAA Sbjct 126 ATFRRFCRCSVSIESIANARSKIDSAFRALASIPRGPVHIALPRDLVDERLPAHQLGTAA 185 Query 181 AGLGGLRTLAPCGPDVADEVIGRLDRSRAPMLVLGNGCRLDGIGEQIVAFCEKAGLPFAT 240 AGLGGLRTLAPCGPDVADEVIGRLDRSRAPMLVLGNGCRLDGIGEQIVAFCEKAGLPFAT Sbjct 186 AGLGGLRTLAPCGPDVADEVIGRLDRSRAPMLVLGNGCRLDGIGEQIVAFCEKAGLPFAT 245 Query 241 TPNGRGIVAETHPLSLGVLGIFGDGRADEYLFDTPCDLLIAVGVSFGGLVTRSFSPRWRG 300 TPNGRGIVAETHPLSLGVLGIFGDGRADEYLFDTPCDLLIAVGVSFGGLVTRSFSPRWRG Sbjct 246 TPNGRGIVAETHPLSLGVLGIFGDGRADEYLFDTPCDLLIAVGVSFGGLVTRSFSPRWRG 305 Query 301 LKADVVHVDPDPSAVGRFVATSLGITTSGRAFVNALNCGRPPRFCRRVGVRPPAPAALPG 360 LKADVVHVDPDPSAVGRFVATSLGITTSGRAFVNALNCGRPPRFCRRVGVRPPAPAALPG Sbjct 306 LKADVVHVDPDPSAVGRFVATSLGITTSGRAFVNALNCGRPPRFCRRVGVRPPAPAALPG 365 Query 361 TPQARGESIHPLELMHELDRELAPNATICADVGTCISWTFRGIPVRRPGRFFATVDFSPM 420 TPQARGESIHPLELMHELDRELAPNATICADVGTCISWTFRGIPVRRPGRFFATVDFSPM Sbjct 366 TPQARGESIHPLELMHELDRELAPNATICADVGTCISWTFRGIPVRRPGRFFATVDFSPM 425 Query 421 GCGIAGAIGVALARPEEHVICIAGDGAFLMHGTEISTAVAHGIRVTWAVLNDGQMSASAG 480 GCGIAGAIGVALARPEEHVICIAGDGAFLMHGTEISTAVAHGIRVTWAVLNDGQMSASAG Sbjct 426 GCGIAGAIGVALARPEEHVICIAGDGAFLMHGTEISTAVAHGIRVTWAVLNDGQMSASAG 485 Query 481 PVSGRMDPSPVARIGANDLAAMARALGAEGIRVDTRCELRAGVQKALAATGPCVLDIAID 540 PVSGRMDPSPVARIGANDLAAMARALGAEGIRVDTRCELRAGVQKALAATGPCVLDIAID Sbjct 486 PVSGRMDPSPVARIGANDLAAMARALGAEGIRVDTRCELRAGVQKALAATGPCVLDIAID 545 Query 541 PEINKPDIGLGR 552 PEINKPDIGLGR Sbjct 546 PEINKPDIGLGR 557 >gi|15610606|ref|NP_217987.1| acetolactate synthase large subunit [Mycobacterium tuberculosis H37Rv] gi|121639390|ref|YP_979614.1| putative acetolactate synthase large subunit ilvB2 [Mycobacterium bovis BCG str. Pasteur 1173P2] gi|148663334|ref|YP_001284857.1| putative acetolactate synthase large subunit [Mycobacterium tuberculosis H37Ra] 41 more sequence titles Length=552 Score = 1089 bits (2816), Expect = 0.0, Method: Compositional matrix adjust. Identities = 551/552 (99%), Positives = 552/552 (100%), Gaps = 0/552 (0%) Query 1 VTVGDHLVARMRAAGISVVCGLPTSRLDSLLVRLSRDAGFQIVLARHEGGAGYLADGFAR 60 +TVGDHLVARMRAAGISVVCGLPTSRLDSLLVRLSRDAGFQIVLARHEGGAGYLADGFAR Sbjct 1 MTVGDHLVARMRAAGISVVCGLPTSRLDSLLVRLSRDAGFQIVLARHEGGAGYLADGFAR 60 Query 61 ASGKSAAVFVAGPGATNVISAVANASVNQVPMLILTGEVAVGEFGLHSQQDTSDDGLGLG 120 ASGKSAAVFVAGPGATNVISAVANASVNQVPMLILTGEVAVGEFGLHSQQDTSDDGLGLG Sbjct 61 ASGKSAAVFVAGPGATNVISAVANASVNQVPMLILTGEVAVGEFGLHSQQDTSDDGLGLG 120 Query 121 ATFRRFCRCSVSIESIANARSKIDSAFRALASIPRGPVHIALPRDLVDERLPAHQLGTAA 180 ATFRRFCRCSVSIESIANARSKIDSAFRALASIPRGPVHIALPRDLVDERLPAHQLGTAA Sbjct 121 ATFRRFCRCSVSIESIANARSKIDSAFRALASIPRGPVHIALPRDLVDERLPAHQLGTAA 180 Query 181 AGLGGLRTLAPCGPDVADEVIGRLDRSRAPMLVLGNGCRLDGIGEQIVAFCEKAGLPFAT 240 AGLGGLRTLAPCGPDVADEVIGRLDRSRAPMLVLGNGCRLDGIGEQIVAFCEKAGLPFAT Sbjct 181 AGLGGLRTLAPCGPDVADEVIGRLDRSRAPMLVLGNGCRLDGIGEQIVAFCEKAGLPFAT 240 Query 241 TPNGRGIVAETHPLSLGVLGIFGDGRADEYLFDTPCDLLIAVGVSFGGLVTRSFSPRWRG 300 TPNGRGIVAETHPLSLGVLGIFGDGRADEYLFDTPCDLLIAVGVSFGGLVTRSFSPRWRG Sbjct 241 TPNGRGIVAETHPLSLGVLGIFGDGRADEYLFDTPCDLLIAVGVSFGGLVTRSFSPRWRG 300 Query 301 LKADVVHVDPDPSAVGRFVATSLGITTSGRAFVNALNCGRPPRFCRRVGVRPPAPAALPG 360 LKADVVHVDPDPSAVGRFVATSLGITTSGRAFVNALNCGRPPRFCRRVGVRPPAPAALPG Sbjct 301 LKADVVHVDPDPSAVGRFVATSLGITTSGRAFVNALNCGRPPRFCRRVGVRPPAPAALPG 360 Query 361 TPQARGESIHPLELMHELDRELAPNATICADVGTCISWTFRGIPVRRPGRFFATVDFSPM 420 TPQARGESIHPLELMHELDRELAPNATICADVGTCISWTFRGIPVRRPGRFFATVDFSPM Sbjct 361 TPQARGESIHPLELMHELDRELAPNATICADVGTCISWTFRGIPVRRPGRFFATVDFSPM 420 Query 421 GCGIAGAIGVALARPEEHVICIAGDGAFLMHGTEISTAVAHGIRVTWAVLNDGQMSASAG 480 GCGIAGAIGVALARPEEHVICIAGDGAFLMHGTEISTAVAHGIRVTWAVLNDGQMSASAG Sbjct 421 GCGIAGAIGVALARPEEHVICIAGDGAFLMHGTEISTAVAHGIRVTWAVLNDGQMSASAG 480 Query 481 PVSGRMDPSPVARIGANDLAAMARALGAEGIRVDTRCELRAGVQKALAATGPCVLDIAID 540 PVSGRMDPSPVARIGANDLAAMARALGAEGIRVDTRCELRAGVQKALAATGPCVLDIAID Sbjct 481 PVSGRMDPSPVARIGANDLAAMARALGAEGIRVDTRCELRAGVQKALAATGPCVLDIAID 540 Query 541 PEINKPDIGLGR 552 PEINKPDIGLGR Sbjct 541 PEINKPDIGLGR 552 >gi|31794646|ref|NP_857139.1| acetolactate synthase large subunit [Mycobacterium bovis AF2122/97] gi|31620243|emb|CAD95686.1| PROBABLE ACETOLACTATE SYNTHASE (LARGE SUBUNIT) ILVB2 (AHAS) (ACETOHYDROXY-ACID SYNTHASE LARGE SUBUNIT) (ALS) [Mycobacterium bovis AF2122/97] Length=552 Score = 1087 bits (2810), Expect = 0.0, Method: Compositional matrix adjust. Identities = 550/552 (99%), Positives = 551/552 (99%), Gaps = 0/552 (0%) Query 1 VTVGDHLVARMRAAGISVVCGLPTSRLDSLLVRLSRDAGFQIVLARHEGGAGYLADGFAR 60 +TVGDHLVARMRAAGISVVCGLPTSRLDSLLVRLSRDAGFQIVLARHEGGAGYLADGFAR Sbjct 1 MTVGDHLVARMRAAGISVVCGLPTSRLDSLLVRLSRDAGFQIVLARHEGGAGYLADGFAR 60 Query 61 ASGKSAAVFVAGPGATNVISAVANASVNQVPMLILTGEVAVGEFGLHSQQDTSDDGLGLG 120 ASGKSAAVFVAGPGATNVISAVANASVNQVPMLILTGEVAVGEFGLHSQQDTSDDGLGLG Sbjct 61 ASGKSAAVFVAGPGATNVISAVANASVNQVPMLILTGEVAVGEFGLHSQQDTSDDGLGLG 120 Query 121 ATFRRFCRCSVSIESIANARSKIDSAFRALASIPRGPVHIALPRDLVDERLPAHQLGTAA 180 ATFRRFCRCSVSIESIANARSKIDSAFRALASIPRGPVHIALPRDLVDERLPAHQLGTAA Sbjct 121 ATFRRFCRCSVSIESIANARSKIDSAFRALASIPRGPVHIALPRDLVDERLPAHQLGTAA 180 Query 181 AGLGGLRTLAPCGPDVADEVIGRLDRSRAPMLVLGNGCRLDGIGEQIVAFCEKAGLPFAT 240 AGLGGLRTLAPCGPDVADEVIGRLDRSRAPMLVLGNGCRLDGIGEQIVAFCEKAGLPFAT Sbjct 181 AGLGGLRTLAPCGPDVADEVIGRLDRSRAPMLVLGNGCRLDGIGEQIVAFCEKAGLPFAT 240 Query 241 TPNGRGIVAETHPLSLGVLGIFGDGRADEYLFDTPCDLLIAVGVSFGGLVTRSFSPRWRG 300 TPNGRGIVAETHPLSLGVLGIFGDGRADEYLFDTPCDLLIAVGVSFGGLVTRSFSPRWRG Sbjct 241 TPNGRGIVAETHPLSLGVLGIFGDGRADEYLFDTPCDLLIAVGVSFGGLVTRSFSPRWRG 300 Query 301 LKADVVHVDPDPSAVGRFVATSLGITTSGRAFVNALNCGRPPRFCRRVGVRPPAPAALPG 360 LKADVVHVDPDPSAVGRFVATSLGITTSGRAFVNALNCGRPPRFCRRVGVRPPAPAALPG Sbjct 301 LKADVVHVDPDPSAVGRFVATSLGITTSGRAFVNALNCGRPPRFCRRVGVRPPAPAALPG 360 Query 361 TPQARGESIHPLELMHELDRELAPNATICADVGTCISWTFRGIPVRRPGRFFATVDFSPM 420 TPQARGESIHPLELMHELDRELAPNATICADVGTCISWTFRGIPVRRPGRFFATVDFSPM Sbjct 361 TPQARGESIHPLELMHELDRELAPNATICADVGTCISWTFRGIPVRRPGRFFATVDFSPM 420 Query 421 GCGIAGAIGVALARPEEHVICIAGDGAFLMHGTEISTAVAHGIRVTWAVLNDGQMSASAG 480 CGIAGAIGVALARPEEHVICIAGDGAFLMHGTEISTAVAHGIRVTWAVLNDGQMSASAG Sbjct 421 ECGIAGAIGVALARPEEHVICIAGDGAFLMHGTEISTAVAHGIRVTWAVLNDGQMSASAG 480 Query 481 PVSGRMDPSPVARIGANDLAAMARALGAEGIRVDTRCELRAGVQKALAATGPCVLDIAID 540 PVSGRMDPSPVARIGANDLAAMARALGAEGIRVDTRCELRAGVQKALAATGPCVLDIAID Sbjct 481 PVSGRMDPSPVARIGANDLAAMARALGAEGIRVDTRCELRAGVQKALAATGPCVLDIAID 540 Query 541 PEINKPDIGLGR 552 PEINKPDIGLGR Sbjct 541 PEINKPDIGLGR 552 >gi|339633475|ref|YP_004725117.1| acetolactate synthase (large subunit) ILVB2 [Mycobacterium africanum GM041182] gi|339332831|emb|CCC28554.1| putative acetolactate synthase (large subunit) ILVB2 [Mycobacterium africanum GM041182] Length=552 Score = 1085 bits (2807), Expect = 0.0, Method: Compositional matrix adjust. Identities = 550/552 (99%), Positives = 551/552 (99%), Gaps = 0/552 (0%) Query 1 VTVGDHLVARMRAAGISVVCGLPTSRLDSLLVRLSRDAGFQIVLARHEGGAGYLADGFAR 60 +TVGDHLVARMRAAGISVVCGLPTSRLDSLLVRLSRDAGFQIVLARHEGGAGYLADGFAR Sbjct 1 MTVGDHLVARMRAAGISVVCGLPTSRLDSLLVRLSRDAGFQIVLARHEGGAGYLADGFAR 60 Query 61 ASGKSAAVFVAGPGATNVISAVANASVNQVPMLILTGEVAVGEFGLHSQQDTSDDGLGLG 120 ASGKSAAVFVAGPGATNVISAVANASVNQVPMLILTGEVAVGEFGLHSQQDTSDDGLGLG Sbjct 61 ASGKSAAVFVAGPGATNVISAVANASVNQVPMLILTGEVAVGEFGLHSQQDTSDDGLGLG 120 Query 121 ATFRRFCRCSVSIESIANARSKIDSAFRALASIPRGPVHIALPRDLVDERLPAHQLGTAA 180 ATFRRFCRCSVSIESIANARSKIDSAFRALASIPRGPVHIALPRDLVDERLPAHQLGTAA Sbjct 121 ATFRRFCRCSVSIESIANARSKIDSAFRALASIPRGPVHIALPRDLVDERLPAHQLGTAA 180 Query 181 AGLGGLRTLAPCGPDVADEVIGRLDRSRAPMLVLGNGCRLDGIGEQIVAFCEKAGLPFAT 240 AGLGGLRTLAPCGPDVADEVIGRLDRSRAPMLVLGNGCRLDGIGEQIVAFCEKAGLPFAT Sbjct 181 AGLGGLRTLAPCGPDVADEVIGRLDRSRAPMLVLGNGCRLDGIGEQIVAFCEKAGLPFAT 240 Query 241 TPNGRGIVAETHPLSLGVLGIFGDGRADEYLFDTPCDLLIAVGVSFGGLVTRSFSPRWRG 300 TPNGRGIVAETHPLSLGVLGIFGDGRADEYLFDTPCDLLIAVGVSFGGLVTRSFSPRW G Sbjct 241 TPNGRGIVAETHPLSLGVLGIFGDGRADEYLFDTPCDLLIAVGVSFGGLVTRSFSPRWLG 300 Query 301 LKADVVHVDPDPSAVGRFVATSLGITTSGRAFVNALNCGRPPRFCRRVGVRPPAPAALPG 360 LKADVVHVDPDPSAVGRFVATSLGITTSGRAFVNALNCGRPPRFCRRVGVRPPAPAALPG Sbjct 301 LKADVVHVDPDPSAVGRFVATSLGITTSGRAFVNALNCGRPPRFCRRVGVRPPAPAALPG 360 Query 361 TPQARGESIHPLELMHELDRELAPNATICADVGTCISWTFRGIPVRRPGRFFATVDFSPM 420 TPQARGESIHPLELMHELDRELAPNATICADVGTCISWTFRGIPVRRPGRFFATVDFSPM Sbjct 361 TPQARGESIHPLELMHELDRELAPNATICADVGTCISWTFRGIPVRRPGRFFATVDFSPM 420 Query 421 GCGIAGAIGVALARPEEHVICIAGDGAFLMHGTEISTAVAHGIRVTWAVLNDGQMSASAG 480 GCGIAGAIGVALARPEEHVICIAGDGAFLMHGTEISTAVAHGIRVTWAVLNDGQMSASAG Sbjct 421 GCGIAGAIGVALARPEEHVICIAGDGAFLMHGTEISTAVAHGIRVTWAVLNDGQMSASAG 480 Query 481 PVSGRMDPSPVARIGANDLAAMARALGAEGIRVDTRCELRAGVQKALAATGPCVLDIAID 540 PVSGRMDPSPVARIGANDLAAMARALGAEGIRVDTRCELRAGVQKALAATGPCVLDIAID Sbjct 481 PVSGRMDPSPVARIGANDLAAMARALGAEGIRVDTRCELRAGVQKALAATGPCVLDIAID 540 Query 541 PEINKPDIGLGR 552 PEINKPDIGLGR Sbjct 541 PEINKPDIGLGR 552 >gi|340628440|ref|YP_004746892.1| putative acetolactate synthase large subunit ILVB2 [Mycobacterium canettii CIPT 140010059] gi|340006630|emb|CCC45817.1| putative acetolactate synthase (large subunit) ILVB2 (AHAS) (acetohydroxy-acid synthase large subunit) (ALS) [Mycobacterium canettii CIPT 140010059] Length=552 Score = 1074 bits (2777), Expect = 0.0, Method: Compositional matrix adjust. Identities = 544/552 (99%), Positives = 548/552 (99%), Gaps = 0/552 (0%) Query 1 VTVGDHLVARMRAAGISVVCGLPTSRLDSLLVRLSRDAGFQIVLARHEGGAGYLADGFAR 60 +TVGDHLVARMRAAGISVVCGLPTSRLDSLLVRLSRDAGF+IVLARHEGGAGYLADGFAR Sbjct 1 MTVGDHLVARMRAAGISVVCGLPTSRLDSLLVRLSRDAGFRIVLARHEGGAGYLADGFAR 60 Query 61 ASGKSAAVFVAGPGATNVISAVANASVNQVPMLILTGEVAVGEFGLHSQQDTSDDGLGLG 120 ASGKSAAVF AGPGATNVISAVANASVNQVPMLILTGEVAVGEFGLHSQQDTSDDGLGLG Sbjct 61 ASGKSAAVFAAGPGATNVISAVANASVNQVPMLILTGEVAVGEFGLHSQQDTSDDGLGLG 120 Query 121 ATFRRFCRCSVSIESIANARSKIDSAFRALASIPRGPVHIALPRDLVDERLPAHQLGTAA 180 TFRRFCRCSVSIESIANARSKIDSAFRALASIPRGPVHIALPRDLVDE LPAHQLGTAA Sbjct 121 PTFRRFCRCSVSIESIANARSKIDSAFRALASIPRGPVHIALPRDLVDEGLPAHQLGTAA 180 Query 181 AGLGGLRTLAPCGPDVADEVIGRLDRSRAPMLVLGNGCRLDGIGEQIVAFCEKAGLPFAT 240 AGLGGLRTLAPCGPDVADEVIGRLDRSRAPMLVLGNGCRLDGIGE+IVAFCEKA LPFAT Sbjct 181 AGLGGLRTLAPCGPDVADEVIGRLDRSRAPMLVLGNGCRLDGIGERIVAFCEKAELPFAT 240 Query 241 TPNGRGIVAETHPLSLGVLGIFGDGRADEYLFDTPCDLLIAVGVSFGGLVTRSFSPRWRG 300 TPNGRGIVAETHPLSLGVLG+FGDGRADEYLFDTPCDLLIAVGVSFGGLVTRSFSPRWRG Sbjct 241 TPNGRGIVAETHPLSLGVLGMFGDGRADEYLFDTPCDLLIAVGVSFGGLVTRSFSPRWRG 300 Query 301 LKADVVHVDPDPSAVGRFVATSLGITTSGRAFVNALNCGRPPRFCRRVGVRPPAPAALPG 360 LKADVVHVDPDPSAVGRFVATSLGITTSGRAFVNALNCGRPPRFCRRVGVRPPAPAALPG Sbjct 301 LKADVVHVDPDPSAVGRFVATSLGITTSGRAFVNALNCGRPPRFCRRVGVRPPAPAALPG 360 Query 361 TPQARGESIHPLELMHELDRELAPNATICADVGTCISWTFRGIPVRRPGRFFATVDFSPM 420 TPQARGESIHPLELMHELDRELAPNATICADVGTCISWTFRGIPVRRPGRFFATVDFSPM Sbjct 361 TPQARGESIHPLELMHELDRELAPNATICADVGTCISWTFRGIPVRRPGRFFATVDFSPM 420 Query 421 GCGIAGAIGVALARPEEHVICIAGDGAFLMHGTEISTAVAHGIRVTWAVLNDGQMSASAG 480 GCGIAGAIGVALARPEEHVICIAGDGAFLMHGTEISTAVAHGIRVTWAVLNDGQMSASAG Sbjct 421 GCGIAGAIGVALARPEEHVICIAGDGAFLMHGTEISTAVAHGIRVTWAVLNDGQMSASAG 480 Query 481 PVSGRMDPSPVARIGANDLAAMARALGAEGIRVDTRCELRAGVQKALAATGPCVLDIAID 540 PVSGRMDPSPVARIGANDLAAMARALGAEGIRVDTRCELRAGVQKALAATGPCVLDIAID Sbjct 481 PVSGRMDPSPVARIGANDLAAMARALGAEGIRVDTRCELRAGVQKALAATGPCVLDIAID 540 Query 541 PEINKPDIGLGR 552 PEINKPDIGLGR Sbjct 541 PEINKPDIGLGR 552 >gi|15843082|ref|NP_338119.1| acetolactate synthase, large subunit, putative [Mycobacterium tuberculosis CDC1551] gi|13883427|gb|AAK47933.1| acetolactate synthase, large subunit, putative [Mycobacterium tuberculosis CDC1551] Length=542 Score = 1071 bits (2769), Expect = 0.0, Method: Compositional matrix adjust. Identities = 542/542 (100%), Positives = 542/542 (100%), Gaps = 0/542 (0%) Query 11 MRAAGISVVCGLPTSRLDSLLVRLSRDAGFQIVLARHEGGAGYLADGFARASGKSAAVFV 70 MRAAGISVVCGLPTSRLDSLLVRLSRDAGFQIVLARHEGGAGYLADGFARASGKSAAVFV Sbjct 1 MRAAGISVVCGLPTSRLDSLLVRLSRDAGFQIVLARHEGGAGYLADGFARASGKSAAVFV 60 Query 71 AGPGATNVISAVANASVNQVPMLILTGEVAVGEFGLHSQQDTSDDGLGLGATFRRFCRCS 130 AGPGATNVISAVANASVNQVPMLILTGEVAVGEFGLHSQQDTSDDGLGLGATFRRFCRCS Sbjct 61 AGPGATNVISAVANASVNQVPMLILTGEVAVGEFGLHSQQDTSDDGLGLGATFRRFCRCS 120 Query 131 VSIESIANARSKIDSAFRALASIPRGPVHIALPRDLVDERLPAHQLGTAAAGLGGLRTLA 190 VSIESIANARSKIDSAFRALASIPRGPVHIALPRDLVDERLPAHQLGTAAAGLGGLRTLA Sbjct 121 VSIESIANARSKIDSAFRALASIPRGPVHIALPRDLVDERLPAHQLGTAAAGLGGLRTLA 180 Query 191 PCGPDVADEVIGRLDRSRAPMLVLGNGCRLDGIGEQIVAFCEKAGLPFATTPNGRGIVAE 250 PCGPDVADEVIGRLDRSRAPMLVLGNGCRLDGIGEQIVAFCEKAGLPFATTPNGRGIVAE Sbjct 181 PCGPDVADEVIGRLDRSRAPMLVLGNGCRLDGIGEQIVAFCEKAGLPFATTPNGRGIVAE 240 Query 251 THPLSLGVLGIFGDGRADEYLFDTPCDLLIAVGVSFGGLVTRSFSPRWRGLKADVVHVDP 310 THPLSLGVLGIFGDGRADEYLFDTPCDLLIAVGVSFGGLVTRSFSPRWRGLKADVVHVDP Sbjct 241 THPLSLGVLGIFGDGRADEYLFDTPCDLLIAVGVSFGGLVTRSFSPRWRGLKADVVHVDP 300 Query 311 DPSAVGRFVATSLGITTSGRAFVNALNCGRPPRFCRRVGVRPPAPAALPGTPQARGESIH 370 DPSAVGRFVATSLGITTSGRAFVNALNCGRPPRFCRRVGVRPPAPAALPGTPQARGESIH Sbjct 301 DPSAVGRFVATSLGITTSGRAFVNALNCGRPPRFCRRVGVRPPAPAALPGTPQARGESIH 360 Query 371 PLELMHELDRELAPNATICADVGTCISWTFRGIPVRRPGRFFATVDFSPMGCGIAGAIGV 430 PLELMHELDRELAPNATICADVGTCISWTFRGIPVRRPGRFFATVDFSPMGCGIAGAIGV Sbjct 361 PLELMHELDRELAPNATICADVGTCISWTFRGIPVRRPGRFFATVDFSPMGCGIAGAIGV 420 Query 431 ALARPEEHVICIAGDGAFLMHGTEISTAVAHGIRVTWAVLNDGQMSASAGPVSGRMDPSP 490 ALARPEEHVICIAGDGAFLMHGTEISTAVAHGIRVTWAVLNDGQMSASAGPVSGRMDPSP Sbjct 421 ALARPEEHVICIAGDGAFLMHGTEISTAVAHGIRVTWAVLNDGQMSASAGPVSGRMDPSP 480 Query 491 VARIGANDLAAMARALGAEGIRVDTRCELRAGVQKALAATGPCVLDIAIDPEINKPDIGL 550 VARIGANDLAAMARALGAEGIRVDTRCELRAGVQKALAATGPCVLDIAIDPEINKPDIGL Sbjct 481 VARIGANDLAAMARALGAEGIRVDTRCELRAGVQKALAATGPCVLDIAIDPEINKPDIGL 540 Query 551 GR 552 GR Sbjct 541 GR 542 >gi|289576206|ref|ZP_06456433.1| acetolactate synthase large subunit ilvB2 [Mycobacterium tuberculosis K85] gi|289540637|gb|EFD45215.1| acetolactate synthase large subunit ilvB2 [Mycobacterium tuberculosis K85] Length=372 Score = 718 bits (1853), Expect = 0.0, Method: Compositional matrix adjust. Identities = 365/366 (99%), Positives = 366/366 (100%), Gaps = 0/366 (0%) Query 1 VTVGDHLVARMRAAGISVVCGLPTSRLDSLLVRLSRDAGFQIVLARHEGGAGYLADGFAR 60 +TVGDHLVARMRAAGISVVCGLPTSRLDSLLVRLSRDAGFQIVLARHEGGAGYLADGFAR Sbjct 1 MTVGDHLVARMRAAGISVVCGLPTSRLDSLLVRLSRDAGFQIVLARHEGGAGYLADGFAR 60 Query 61 ASGKSAAVFVAGPGATNVISAVANASVNQVPMLILTGEVAVGEFGLHSQQDTSDDGLGLG 120 ASGKSAAVFVAGPGATNVISAVANASVNQVPMLILTGEVAVGEFGLHSQQDTSDDGLGLG Sbjct 61 ASGKSAAVFVAGPGATNVISAVANASVNQVPMLILTGEVAVGEFGLHSQQDTSDDGLGLG 120 Query 121 ATFRRFCRCSVSIESIANARSKIDSAFRALASIPRGPVHIALPRDLVDERLPAHQLGTAA 180 ATFRRFCRCSVSIESIANARSKIDSAFRALASIPRGPVHIALPRDLVDERLPAHQLGTAA Sbjct 121 ATFRRFCRCSVSIESIANARSKIDSAFRALASIPRGPVHIALPRDLVDERLPAHQLGTAA 180 Query 181 AGLGGLRTLAPCGPDVADEVIGRLDRSRAPMLVLGNGCRLDGIGEQIVAFCEKAGLPFAT 240 AGLGGLRTLAPCGPDVADEVIGRLDRSRAPMLVLGNGCRLDGIGEQIVAFCEKAGLPFAT Sbjct 181 AGLGGLRTLAPCGPDVADEVIGRLDRSRAPMLVLGNGCRLDGIGEQIVAFCEKAGLPFAT 240 Query 241 TPNGRGIVAETHPLSLGVLGIFGDGRADEYLFDTPCDLLIAVGVSFGGLVTRSFSPRWRG 300 TPNGRGIVAETHPLSLGVLGIFGDGRADEYLFDTPCDLLIAVGVSFGGLVTRSFSPRWRG Sbjct 241 TPNGRGIVAETHPLSLGVLGIFGDGRADEYLFDTPCDLLIAVGVSFGGLVTRSFSPRWRG 300 Query 301 LKADVVHVDPDPSAVGRFVATSLGITTSGRAFVNALNCGRPPRFCRRVGVRPPAPAALPG 360 LKADVVHVDPDPSAVGRFVATSLGITTSGRAFVNALNCGRPPRFCRRVGVRPPAPAALPG Sbjct 301 LKADVVHVDPDPSAVGRFVATSLGITTSGRAFVNALNCGRPPRFCRRVGVRPPAPAALPG 360 Query 361 TPQARG 366 TPQARG Sbjct 361 TPQARG 366 >gi|189424179|ref|YP_001951356.1| thiamine pyrophosphate protein TPP binding domain-containing protein [Geobacter lovleyi SZ] gi|189420438|gb|ACD94836.1| thiamine pyrophosphate protein TPP binding domain protein [Geobacter lovleyi SZ] Length=562 Score = 251 bits (642), Expect = 2e-64, Method: Compositional matrix adjust. Identities = 177/549 (33%), Positives = 280/549 (52%), Gaps = 23/549 (4%) Query 7 LVARMRAAGISVVCGLPTSRLDSLLVRLSRDAGFQIVLARHEGGAGYLADGFARASGKSA 66 +V + G++ V G+P ++SL L + + +++A+HE GA ++ADG+AR SG A Sbjct 7 IVRSLEKHGVTCVFGVPGGAIESLNTALYKSS-ISVIVAKHEEGAAFMADGYARVSGVIA 65 Query 67 AV-FVAGPGATNVISAVANASVNQVPMLILTGEVAVGEFGLHSQQDTSDDGLGLGATFRR 125 AGPGATN+I+ +A+A + +P++ LTG+V+ FG + Q+ S G+ + FR+ Sbjct 66 VCCSTAGPGATNMITGIASAFGDSIPVIALTGQVSTSLFGKGAIQEFSVQSFGIVSIFRQ 125 Query 126 FCRCSVSIESIANARSKIDSAFRALASIPRGPVHIALPRDLVDERLP--AHQLGTAAAGL 183 + S I + A I A R + +GPVH+ LP D++ ++ +H+ + L Sbjct 126 ITKYSDIIINENKAGEMISRARRLALTGRKGPVHLNLPADIMKRKVTDDSHERCSTTQVL 185 Query 184 GGLRTLAPCGPDVADEVIGRLDRSRAPMLVLGNGCRLDGIGEQIVAFCEKAGLPFATTPN 243 G R A ++G ++ P++V G G L ++++ E +P AT+P Sbjct 186 GFDREAVK---KAAQLLLG----AKRPVIVAGWGTVLSRADKELLELAELLDIPVATSPK 238 Query 244 GRGIVAETHPLSLGVLGIFGDGRADEYLFDTPCDLLIAVGVSFGGLVTRSFSPRWRGLKA 303 +GI++E HPLSLGVLG G A EY+ D+L+AVG SF VT + R +K+ Sbjct 239 AKGILSEVHPLSLGVLGFAGSPVAKEYILKRDVDVLLAVGTSFNEFVTSGWDKRLLPMKS 298 Query 304 DVVHVDPDPSAVGRFVATSLGITTSGRAFVNAL-------NCGRPPRFCRRVGVRPPAPA 356 ++HVD D + +G+ +GI + L GR RR V A Sbjct 299 -LIHVDIDCNEIGKNYYVHVGIAGDAATVLRELVFEIGRIRKGRRIENTRRKEVEQVRAA 357 Query 357 ALPGTPQARGESIHPLELMHELDRELAPNATICADVGTCISWTFRGIPVRRPGRFFATVD 416 L T + P L+ +L+ L N AD G ++W R + + P F+ + Sbjct 358 LLVKTRKQNKALYSPHRLIMDLNEALPKNTLYFADNGNSMAWAIRYLTITEPYSFYVGLG 417 Query 417 FSPMGCGIAGAIGVALARPEEHVICIAGDGAFLMHGTEISTAVAHGIRVTWAVLNDGQ-- 474 F+ MG +A IG LA + V+ + GDG+FLM+G E++TAV + I V W ++N+ Sbjct 418 FASMGFAVAAPIGAKLAAGDRPVVALVGDGSFLMNGMEVATAVNYNIPVIWVIMNNAMLG 477 Query 475 MSASAGPVSGRMDPSPVARIGANDLAAMARALGAEGIRVDTRCEL-RAGVQKALAATGPC 533 M ++G + P + D +A ALGA GIR+ T E+ R + LAA P Sbjct 478 MVYHGRKLAGIPEGIP-SGFKPVDHVKLAEALGARGIRITTPGEINRELMDDILAAGVPT 536 Query 534 VLDIAIDPE 542 VLD+ IDPE Sbjct 537 VLDVIIDPE 545 >gi|298243379|ref|ZP_06967186.1| thiamine pyrophosphate protein TPP binding domain protein [Ktedonobacter racemifer DSM 44963] gi|297556433|gb|EFH90297.1| thiamine pyrophosphate protein TPP binding domain protein [Ktedonobacter racemifer DSM 44963] Length=598 Score = 229 bits (585), Expect = 8e-58, Method: Compositional matrix adjust. Identities = 162/559 (29%), Positives = 258/559 (47%), Gaps = 30/559 (5%) Query 6 HLVAR-MRAAGISVVCGLPTSRLDSLLVRLSRDAGFQIVLARHEGGAGYLADGFARAS-G 63 H++ R + G++ + G+P L L L++ Q VLA+HE GA ++A+G+AR S G Sbjct 27 HILLRTLEEVGVTHIFGVPGGPLVPLFEALAQRQRIQPVLAKHEEGAAFMAEGYARVSRG 86 Query 64 KSAAVFVAGPGATNVISAVANASVNQVPMLILTGEVAVGEFGLHSQQDTS--DDGLGLGA 121 +GPGATN+++ + +A+ + +P+L LTG+VA FG QD+S + + + Sbjct 87 LGVCCGTSGPGATNLLTGITSATSDSIPVLALTGQVATSAFGKGGLQDSSSGNRTIDIVE 146 Query 122 TFRRFCRCSVSIESIANARSKIDSAFRALASIPRGPVHIALPRDLV-----DERLPAHQL 176 +R + S+ ++S + I RA + G VH+ LP D+V D+ LP + Sbjct 147 AYRTASKLSLMLQSGQQMQHVIRRMIRAALTGRPGAVHLNLPADVVKQSVPDDGLPVTKF 206 Query 177 GTAAAGLGGLRTLAPCGPDVADEVIGRLDRSRAPMLVLGNGCRLDGIGEQIVAFCEKAGL 236 T TL P V L ++ P L++G+G L G + E + Sbjct 207 FT--------HTLPSGDPAAIQRVATTLQTAKRPALLVGHGVNLSGAWSLLQRVAEALQI 258 Query 237 PFATTPNGRGIVAETHPLSLGVLGIFGDGRADEYLFDTPCDLLIAVGVSFGGLVTRSFSP 296 P ATT G+ E HPLSLGV G G A+ YL+ D+L+ +G S G T + Sbjct 259 PVATTLKGKSAFPERHPLSLGVFGFGGHPLAEAYLYSEEVDVLVIIGTSLGEFQTNGWDK 318 Query 297 RWRGLKADVVHVDPDPSAVGRFVATSLGITTSGRAFVNAL----------NCGRP-PRFC 345 R ++ +D DP +G + +A + AL + RP P Sbjct 319 RLAPPHRTIIQIDLDPLTIGNIYPVDQSVVGDAKAILKALAEALGTLALHHQERPRPTDS 378 Query 346 RRVGVRPPAPAALPGTPQARGESI-HPLELMHELDRELAPNATICADVGTCISWTFRGIP 404 +R P +G S+ P ++ +++ L + D G C+SW + Sbjct 379 VLEHMRAETPRYYSAEMLQQGASLLKPQAVVSKMNEALPDETLLFVDNGNCLSWAGQFYE 438 Query 405 VRRPGRFFATVDFSPMGCGIAGAIGVALARPEEHVICIAGDGAFLMHGTEISTAVAHGIR 464 R+PG F + + MG IA AIG +A P+ V+ + GDGAF MHG EI TA + + Sbjct 439 ARQPGTVFCATNTASMGYAIAAAIGGKVAAPQRPVVALLGDGAFGMHGMEIHTAAEYHLP 498 Query 465 VTWAVLNDGQMSASAGPVSGRMDPSPVARIGAN-DLAAMARALGAEGIRVDTRCELRAGV 523 + W VLN+G S + G D+ A+A +G + + E + Sbjct 499 IIWVVLNNGGHGMVYNGEKLLNGQSYLTTFGTPLDVCAIAWGIGIDAFKATNLAEFEGAL 558 Query 524 QKALAATGPCVLDIAIDPE 542 + AL A PCV+++ +D E Sbjct 559 RHALEAQVPCVIEVMVDLE 577 >gi|334338960|ref|YP_004543940.1| acetolactate synthase large subunit biosynthetic type [Desulfotomaculum ruminis DSM 2154] gi|334090314|gb|AEG58654.1| acetolactate synthase, large subunit, biosynthetic type [Desulfotomaculum ruminis DSM 2154] Length=553 Score = 223 bits (568), Expect = 7e-56, Method: Compositional matrix adjust. Identities = 162/555 (30%), Positives = 263/555 (48%), Gaps = 43/555 (7%) Query 7 LVARMRAAGISVVCGLPTSRLDSLLVRLSRDAGFQIVLARHEGGAGYLADGFARASGKSA 66 L+ ++ AG+ + G P + + L D+ Q +L RHE GA + ADG+ARASGK Sbjct 9 LIDSLKEAGVETIFGYPGGQALPIYDAL-YDSDLQHILVRHEQGAAHAADGYARASGKVG 67 Query 67 AVF-VAGPGATNVISAVANASVNQVPMLILTGEVAVGEFGLHSQQDTSDDGLGLGATFRR 125 +GPGATN+++ +ANA ++ VPM+ +TG+V G S Q+ G+ L T Sbjct 68 VCLATSGPGATNLVTGIANAYMDSVPMVAITGQVPTFLLGRDSFQEVDITGITLPITKHN 127 Query 126 FCRCSVSIESIANARSKIDSAFRALASIPRGPVHIALPRDLVDERLPAHQLGTAAAGLGG 185 + ++ I + + AF ++ GPV I +P+D+ + + G L G Sbjct 128 YI-----VKDIKDMGRIVKEAFYVASTGRPGPVLIDIPKDISSGEMDYERNG--CLNLPG 180 Query 186 LRTLAPCGPDVADEVIGRLDRSRAPMLVLGNGCRLDGIGEQIVAFCEKAGLPFATTPNGR 245 D+ ++ + + SR P++ G G G +++ E P T G Sbjct 181 YNPPREAREDLVNQALRAIAESRCPVIYAGGGVISSGAHQELKKLSETLLAPVTVTLMGL 240 Query 246 GIVAETHPLSLGVLGIFGDGRADEYLFDTPCDLLIAVGVSFGGLVT---RSFSPRWRGLK 302 G HPLSLG+LG+ G A+ + + CDLLIAVGV F VT SF+ Sbjct 241 GGFPGDHPLSLGMLGMHGSKYANYAVCE--CDLLIAVGVRFDDRVTGKIESFAS-----N 293 Query 303 ADVVHVDPDPSAVGRFVATSLGITTSGRAFVNALNCGRPPRFCRRVGVRPPA-------- 354 A ++H+D DP+ +G+ V + +T + +N L R+ R P Sbjct 294 AKIIHIDIDPAEMGKNVQVDIPVTGDVKLVLNQL--------LERLEARIPTAWQEKIAA 345 Query 355 -PAALPGTPQARGESIHPLELMHELDRELAPNATICADVGTCISWTFRGIPVRRPGRFFA 413 P GE++ P +++ E+DR+ + A I +VG W + +P F + Sbjct 346 WKKEYPFDYDRTGETLKPQQIIREIDRQTSGQARITTEVGQHQMWAAQYYTYTKPRSFIS 405 Query 414 TVDFSPMGCGIAGAIGVALARPEEHVICIAGDGAFLMHGTEISTAVAHGIRVTWAVLNDG 473 + MG G AIGV +A PEE V IAGDG+ M+ E++TAV + + V A++N+G Sbjct 406 SGGLGTMGYGFPAAIGVQVACPEETVFDIAGDGSIQMNIQELATAVNYELPVNVAIMNNG 465 Query 474 QM----SASAGPVSGRMDPSPVARIGANDLAAMARALGAEGIRVDTRCELRAGVQKALAA 529 + + R S + + D +A + GAEG R+ + E+ +Q A+ + Sbjct 466 YLGMVRQWQEMLYNRRYSQS---EMKSPDFVKLAESYGAEGYRITRKEEVTPVLQAAIQS 522 Query 530 TGPCVLDIAIDPEIN 544 P ++D ++PE N Sbjct 523 RKPVLMDFVVEPEEN 537 >gi|308274605|emb|CBX31204.1| hypothetical protein N47_E47160 [uncultured Desulfobacterium sp.] Length=604 Score = 218 bits (555), Expect = 2e-54, Method: Compositional matrix adjust. Identities = 176/589 (30%), Positives = 269/589 (46%), Gaps = 56/589 (9%) Query 1 VTVGDHLVARMRAAGISVVCGLPTSRLDSL---LVRLSRDAGFQIVLARHEGGAGYLADG 57 +T+ D +V + G+ V +P L +L LVR R G + +L RHE G+ ++ADG Sbjct 32 MTLSDLIVGYLEQFGVEYVFSVPGGPLGALYDALVRSQRRGGPRSILTRHENGSAFMADG 91 Query 58 FARASGK-SAAVFVAGPGATNVISAVANASVNQVPMLILTGEVAVGEFGLHSQQDTSDDG 116 +AR +GK GPGATN+I+ VA A + +P+L++T + A+ +FG Q++S D Sbjct 92 YARETGKIGVCCSTTGPGATNLITGVAEAYADHIPLLVITTQTALPDFGRGCFQESSADV 151 Query 117 LGLGATFRRFCRCSVSIESIANA-RSKIDSAFRALASIPRGPVHIALPRDLVDERLPAHQ 175 + F C C S+ S + +K+ +AF A + P+GP H+++P D++ RL +++ Sbjct 152 TDIMGMFDH-CTCYNSLVSHPDQLENKLVAAFTAAFNPPKGPAHLSIPVDIL--RLASNK 208 Query 176 ----------LGTAAAGLGGLRTLAPCGPDVADEVIGRLDRSRAPMLVLGNGCRLDGIGE 225 L +A + L L G D+ D L ++R +++ G+GC G + Sbjct 209 PVSFPNLHNLLAEPSATVDSL-ALDKLGQDLTD----VLRQNRNVVILAGHGC--GGAAQ 261 Query 226 QIVAFCEKAGLPFATTPNGRGIVAETHPLSLGVLGIFGDGRADEYLFDTPCDLLIAVGVS 285 Q++ F E G +T G+ V HP LGV G G A + L D DL++A+G Sbjct 262 QLIEFAEHTGANIVSTQRGKSWVNPYHPQYLGVFGFSGHKTARQALADKSVDLILAIGTD 321 Query 286 FGGLVTRSFSPRWRGLKADVVHVDPDPSAVGRFVATSLGITTSGRAFVNAL--------N 337 T + P K +VH+ SA R + I + R L Sbjct 322 LNEWATGGWDPVLMNHK--LVHIHNFSSAFTRSPMARMHICGTIRTIFEGLVLRIKTAKQ 379 Query 338 CGRPP-------RFCRRVGVRPPAPAALPGTPQARGES----IHPLELMHELDRELAPNA 386 G+ P + + PP + T R E I P + E+ N Sbjct 380 EGKLPASLSGSSQIYNKNISYPPPQIKIMATESCRKEKTDSLIKPQRVFREIIERFPHNT 439 Query 387 TICADVGTCISWTFRGIPVRRPGRFFATVDFSPMGCGIAGAIGVALARPEEHVICIAGDG 446 D + W+ P + ++ F+ MG I ++GVAL P+ V+C GDG Sbjct 440 RFLIDNSNSVPWSIHYFFHPHPENYHLSIGFASMGWAIGASVGVALGAPDRPVVCFTGDG 499 Query 447 AFLMHGTEISTAVAHGIRVTWAVLNDGQ--MSASAGPVSGR--MDPSPVARIGANDLAAM 502 FLM G EI+ AV + V + VLND M +SG +D S I A D M Sbjct 500 CFLMSGQEITVAVQEKLPVVFVVLNDKAYGMIKHGHRLSGSEAVDYS----ISAVDFCMM 555 Query 503 ARALGAEGIRVDTRCELRAGVQKAL-AATGPCVLDIAIDPEINKPDIGL 550 ARA+GA+ + + KAL GP +LDI IDPE KP +G+ Sbjct 556 ARAVGAQAYAIRKPEDFDKIDYKALCKQKGPTLLDIHIDPE-EKPPLGM 603 >gi|307150286|ref|YP_003885670.1| acetolactate synthase large subunit [Cyanothece sp. PCC 7822] gi|306980514|gb|ADN12395.1| acetolactate synthase, large subunit, biosynthetic type [Cyanothece sp. PCC 7822] Length=619 Score = 218 bits (554), Expect = 3e-54, Method: Compositional matrix adjust. Identities = 163/557 (30%), Positives = 261/557 (47%), Gaps = 34/557 (6%) Query 7 LVARMRAAGISVVCGLPTSRLDSLLVRLSRDAG---FQIVLARHEGGAGYLADGFARASG 63 L+ ++ G+ + G P + + L R Q +L RHE GA + ADG+ARA+G Sbjct 25 LMDSLKRHGVKHIFGYPGGAILPIYDELYRSEARGDIQHILVRHEQGAAHAADGYARATG 84 Query 64 KSAAVF-VAGPGATNVISAVANASVNQVPMLILTGEVAVGEFGLHSQQDTSDDGLGLGAT 122 K F +GPGATN+++ +A A ++ +P++I+TG+V+ G + Q+T G+ L Sbjct 85 KVGVCFGTSGPGATNLVTGIATAHMDSIPLVIITGQVSRPAIGSDAFQETDIFGITLP-- 142 Query 123 FRRFCRCSVSIESIANARSKIDSAFRALASIPRGPVHIALPRDLVDERLPAHQLGTAAAG 182 + S + + ++ + AF ++ GPV I +P+D+ E + Sbjct 143 ---IVKHSYVVRNASDMAQIVAEAFHIASTGRPGPVLIDIPKDVGLEVCDYIPVEPGDVK 199 Query 183 LGGLRTLAPCGPDVADEVIGRLDRSRAPMLVLGNGCRLDGIGEQIVAFCEKAGLPFATTP 242 L G R P + + LD + P+L +G G Q+ E+ +P TT Sbjct 200 LPGYRPTVKGNPRQINAALQLLDAAERPLLYVGGGAIAANAHAQVHELAERFQMPVTTTL 259 Query 243 NGRGIVAETHPLSLGVLGIFGDGRADEYLFDTPCDLLIAVGVSFGGLVTRSFSPRWRGLK 302 G G E HPLSLG+LG+ G A+ + T CDLLIAVG F VT R Sbjct 260 MGLGAFDEHHPLSLGMLGMHGTAYANFAV--TECDLLIAVGARFDDRVTGKLEEFAR--N 315 Query 303 ADVVHVDPDPSAVGRFVATSLGITTSGRAFVNAL-----------NCGRPPRFCRRVG-V 350 A V+H+D DP+ VG+ + I R + + N R + R+ Sbjct 316 AKVIHIDIDPAEVGKVRGPDVPIVGDVRQVLEQILQRVREIDYPTNSTRTKAWLDRINRW 375 Query 351 RPPAPAALPGTPQARGESIHPLELMHELDRELAPNATICADVGTCISWTFRGIPVRRPGR 410 R P +P P +SI P +++ ELDR+ AP A DVG W + + P R Sbjct 376 REDYPLMVPSYP----DSIAPQQVIVELDRQ-APKAYYTTDVGQHQMWAAQFLK-NGPRR 429 Query 411 FFATVDFSPMGCGIAGAIGVALARPEEHVICIAGDGAFLMHGTEISTAVAHGIRVTWAVL 470 + ++ MG G+ A+G +A PEE VIC++GD +F M+ E++T + I+V ++ Sbjct 430 WISSAGLGTMGFGMPAAMGAKVALPEEQVICVSGDASFQMNSQELATLAQYNIQVKTVII 489 Query 471 ND---GQMSASAGPVSGRMDPSPVARIGANDLAAMARALGAEGIRVDTRCELRAGVQKAL 527 N+ G + G S + G + +A+A G +GI V +L + + L Sbjct 490 NNGWQGMVRQWQQTFYGERYSSSNMQPGMPNFELLAQAYGVKGITVTDPAQLSDAIAQML 549 Query 528 AATGPCVLDIAIDPEIN 544 A GP ++D+ + E N Sbjct 550 AHDGPVLVDVHVRREEN 566 >gi|75908969|ref|YP_323265.1| acetolactate synthase 3 catalytic subunit [Anabaena variabilis ATCC 29413] gi|75702694|gb|ABA22370.1| acetolactate synthase, large subunit [Anabaena variabilis ATCC 29413] Length=632 Score = 215 bits (548), Expect = 2e-53, Method: Compositional matrix adjust. Identities = 171/571 (30%), Positives = 264/571 (47%), Gaps = 50/571 (8%) Query 1 VTVGDHLVARMRAAGISVVCGLPTSRLDSL---LVRLSRDAGFQIVLARHEGGAGYLADG 57 VT G L+ + G+ + G P + + L ++ + +L RHE GA + ADG Sbjct 33 VTGGFALLDSLLRHGVEYIFGYPGGAILPIYDDLYKVEATGSLKHILVRHEQGAAHAADG 92 Query 58 FARASGKSAAVF-VAGPGATNVISAVANASVNQVPMLILTGEVAVGEFGLHSQQDTSDDG 116 +ARA+GK F +GPGATN+++ +A A ++ +PM+I+TG+V G + Q+T G Sbjct 93 YARATGKVGVCFGTSGPGATNLVTGIATAYMDSIPMVIVTGQVPRKMIGTDAFQETDIYG 152 Query 117 LGLGATFRRFCRCSVSIESIANARSKIDSAFRALASIPRGPVHIALPRDLVDERLPAHQL 176 + L + S + + + AF ++ GPV I +P+D+ E+ + Sbjct 153 ITL-----PIVKHSYVVRDPQDMARIVAEAFHIASTGRPGPVLIDVPKDVAFEQFDYVPV 207 Query 177 GTAAAGLGGLRTLAPCGPDVADEVIGRLDRSRAPMLVLGNGCRLDGIGEQIVAFCEKAGL 236 + L G R P + I + SR P+L +G G G +I E + Sbjct 208 EPGSIKLRGYRPTVKGNPRQINAAIELIRESRRPLLYVGGGAIASGAHAEIQELAELFNI 267 Query 237 PFATTPNGRGIVAETHPLSLGVLGIFGDGRADEYLFDTPCDLLIAVGVSFGGLVT---RS 293 P TT G G E HPLSLG+LG+ G A+ + D CDLLI VG F VT Sbjct 268 PVTTTLMGIGAFDEHHPLSLGMLGMHGTAYANFAVTD--CDLLICVGARFDDRVTGKLDE 325 Query 294 FSPRWRGLKADVVHVDPDPSAVGRFVATSLGITTSGRAFVNALNCGRPPRFCRRVGV--- 350 F+ R A V+H+D DP+ VG+ + I R + L R C++ G Sbjct 326 FASR-----AKVIHIDIDPAEVGKNRIPEVPIVGDVRKVLLDLL-----RRCKQTGAKNT 375 Query 351 --------------RPPAPAALPGTPQARGESIHPLELMHELDRELAPNATICADVGTCI 396 R P +P P +SI P E++ E+ + AP+A DVG Sbjct 376 PNQNQEWLNLINRWREDYPLVIPQHP----DSIPPQEVIVEVGSQ-APHAFYTTDVGQHQ 430 Query 397 SWTFRGIPVRRPGRFFATVDFSPMGCGIAGAIGVALARPEEHVICIAGDGAFLMHGTEIS 456 W + + P R+ ++ MG G+ AIG +A P+E VICI+GD +F M E+ Sbjct 431 MWAAQFLK-NGPRRWISSAGLGTMGFGLPAAIGAKVAFPDEQVICISGDASFQMCLQELG 489 Query 457 TAVAHGIRVTWAVLND---GQMSASAGPVSGRMDPSPVARIGANDLAAMARALGAEGIRV 513 TA +GI V +LN+ G + G +G D+ +A+A G +GI V Sbjct 490 TASQYGINVKTVILNNGWQGMVRQWQQAFHGERYSCSNMEVGMPDVELLAKAYGIKGIVV 549 Query 514 DTRCELRAGVQKALAATGPCVLDIAIDPEIN 544 R +L+ + + LA GP +LD+ + + N Sbjct 550 TQREQLKDAIAQMLAYDGPVILDVRVTKDEN 580 >gi|298247788|ref|ZP_06971593.1| thiamine pyrophosphate protein TPP binding domain protein [Ktedonobacter racemifer DSM 44963] gi|297550447|gb|EFH84313.1| thiamine pyrophosphate protein TPP binding domain protein [Ktedonobacter racemifer DSM 44963] Length=578 Score = 214 bits (545), Expect = 3e-53, Method: Compositional matrix adjust. Identities = 158/557 (29%), Positives = 256/557 (46%), Gaps = 33/557 (5%) Query 7 LVARMRAAGISVVCGLPTSRLDSLLVRLSRDAGFQIVLARHEGGAGYLADGFARASGKSA 66 L+ + G+ + G+P L L L+ Q VLA+HE GA ++A+G+AR G Sbjct 8 LLQALEEIGVKHIFGVPGGPLVPLFEALAERQHIQPVLAKHEEGAAFMAEGYARVRGGLG 67 Query 67 AVF-VAGPGATNVISAVANASVNQVPMLILTGEVAVGEFGLHSQQDTS--DDGLGLGATF 123 +GPGATN ++ +A+A+ + +P+L LT +VA FG QD+S + + + Sbjct 68 VCCGTSGPGATNALTGIASANSDSIPVLALTAQVATSVFGKGGLQDSSSGNRTADVVDMY 127 Query 124 RRFCRCSVSIESIANARSKIDSAFRALASIPRGPVHIALPRDLV-----DERLPAHQLGT 178 R + S+ +++ + R + G VH+ LP D+V D+ LP T Sbjct 128 RSATKLSLMLQNSQQMQHMARRMIRTALTGRPGAVHLNLPADIVKQPAPDDGLPTTHFFT 187 Query 179 AAAGLGGLRTLAPCGPDVADEVIGRLDR-SRAPMLVLGNGCRLDGIGEQIVAFCEKAGLP 237 + G L A + + R+ R ++ P + G+G + Q+ E +P Sbjct 188 RSTSTGDL---------AAIQKVARILRDAKRPAIFAGHGISVSRAWPQLQRVAETLQIP 238 Query 238 FATTPNGRGIVAETHPLSLGVLGIFGDGRADEYLFDTPCDLLIAVGVSFGGLVTRSFSPR 297 ATT G+ E HPLSLGV G G A+ YL+ D+L+ +G S G T + PR Sbjct 239 VATTLKGKSAFPERHPLSLGVFGFGGHPLAETYLYAEDVDVLLIIGTSLGEFQTNGWDPR 298 Query 298 WRGLKADVVHVDPDPSAVGRFVATSLGITTSGRAFVNALN---CGRPPRFCRRVGVRPPA 354 ++ +D DP A+G + GI +A + L G P V Sbjct 299 LALSHRTIIQIDLDPLAIGNIYPVNHGIVGDAKAVLKVLAAALTGLVPASRGSVSALDRL 358 Query 355 PAALP-----GTPQARGESIHPLELMHELDRELAPNATICADVGTCISWTFRGIPVRRPG 409 +P T Q + P L+ +++ L N + D G C+SW + RRPG Sbjct 359 RKTIPRYYNAKTLQGEASLLKPQALVAKMNEVLPDNTLLFVDNGNCLSWVGQFYEARRPG 418 Query 410 RFFATVDFSPMGCGIAGAIGVALARPEEHVICIAGDGAFLMHGTEISTAVAHGIRVTWAV 469 F + + MG +A +IG +A P++ V+ + GDGAF MHG E+ TA + I V W V Sbjct 419 TVFFATNTASMGYAVAASIGGKIAAPDKPVVALLGDGAFGMHGIEVHTAADYNIPVIWVV 478 Query 470 LNDGQMSASAGPVSGRMDPSPVARIGAND----LAAMARALGAEGIRVDTRCELRAGVQK 525 LN+G +G + V+ + D ++ +A A G +R + + +++ Sbjct 479 LNNG---GHGMVYNGEKLLNGVSYLTTFDKPLNVSGIANAAGVSAVRTTSLDKFEDSLRQ 535 Query 526 ALAATGPCVLDIAIDPE 542 A+ A PCV++ +D E Sbjct 536 AIDARVPCVIEAMVDLE 552 >gi|20093969|ref|NP_613816.1| acetolactate synthase catalytic subunit [Methanopyrus kandleri AV19] gi|19886928|gb|AAM01746.1| Acetolactate synthase, large subunit [Methanopyrus kandleri AV19] Length=565 Score = 214 bits (545), Expect = 3e-53, Method: Compositional matrix adjust. Identities = 159/556 (29%), Positives = 259/556 (47%), Gaps = 40/556 (7%) Query 7 LVARMRAAGISVVCGLPTSRLDSLLVRLSRDAGFQIVLARHEGGAGYLADGFARASGKSA 66 LV ++ G+ + G P + + + + + +L RHE GA + ADG+AR GK Sbjct 11 LVECLKEEGVEHIFGYPGGAVLPIYDEIYDEVSIEHILVRHEQGAAHAADGYARVKGKPG 70 Query 67 AVF-VAGPGATNVISAVANASVNQVPMLILTGEVAVGEFGLHSQQDTSDDGLGLGATFRR 125 +GPGATN+++ +A A ++ P++ +TG+V G + Q+ D +G+ F Sbjct 71 VCMATSGPGATNLVTGIATAYMDSSPVIAITGQVPTTMIGKDAFQEV--DAVGV---FMP 125 Query 126 FCRCSVSIESIANARSKIDSAFRALASIPRGPVHIALPRDL----VDERLPAHQLGTAAA 181 + + I + AF+ + GPVHI +P+D+ VD +P Sbjct 126 ITKHNYQIGKPEEIPEVVKEAFKIAITGRPGPVHIDVPKDVQEAEVDVEIPK---TVEVE 182 Query 182 GLGGLRTLAPCGPDVADEVIGRLDRSRAPMLVLGNGCRLDGIGEQIVAFCEKAGLPFATT 241 GL ++ P A E++ +R P+++ G GC + +++ E G P ATT Sbjct 183 GLNVVKRGHPVQIKRAAELLAEAER---PVILAGGGCVISNATRELIELAELLGAPVATT 239 Query 242 PNGRGIVAETHPLSLGVLGIFGDGRADEYLFDTPCDLLIAVGVSFGGLVT---RSFSPRW 298 G+G E HPL+LG+ G+ G A+ L T CD+L+AVG F T F+P Sbjct 240 LMGKGAFPEDHPLALGMAGMHGTKAANYAL--TECDVLLAVGCRFSDRTTGDPSGFAP-- 295 Query 299 RGLKADVVHVDPDPSAVGRFVATSLGITTSG----RAFVNALNCGRPPRFCRRVGVRP-- 352 +A ++H+D DP+ +G+ + + I R + L + R +R G R Sbjct 296 ---EAKIIHIDIDPAEIGKNIPVDVPIVGDAKLVLRDLIKELKRRKYLRERKRWGERIEE 352 Query 353 -PAPAALPGTPQARGESIHPLELMHELDRELAP-NATICADVGTCISWTFRGIPVRRPGR 410 A +P + I P EL+ L L + + DVG W R PV P R Sbjct 353 LKAEVEMPPESTESDQRISPRELVRVLHEALKDRDYILTTDVGQNQMWMARYFPVEEPRR 412 Query 411 FFATVDFSPMGCGIAGAIGVALARPEEHVICIAGDGAFLMHGTEISTAVAHGIRVTWAVL 470 F ++ MG G+ A+G +A PE+ V+ + GDG FLM E++TAV + I V V+ Sbjct 413 FISSGGLGTMGFGLPAALGAKVAAPEKTVVAVVGDGGFLMTAQELATAVDNDIEVKVFVM 472 Query 471 NDGQMSASAGP----VSGRMDPSPVARIGANDLAAMARALGAEGIRVDTRCELRAGVQKA 526 ++ + A R+ S + D+ + + GA GI V+ EL + V++A Sbjct 473 DNRLLGMVAQWQRLFYDERLSESKLDE--KTDIVKLTESYGAAGITVEEPSELESAVEEA 530 Query 527 LAATGPCVLDIAIDPE 542 G V+D+ +DPE Sbjct 531 FETPGTVVVDVFVDPE 546 >gi|291569589|dbj|BAI91861.1| acetolactate synthase [Arthrospira platensis NIES-39] Length=612 Score = 214 bits (544), Expect = 4e-53, Method: Compositional matrix adjust. Identities = 160/560 (29%), Positives = 263/560 (47%), Gaps = 40/560 (7%) Query 7 LVARMRAAGISVVCGLPTSRLDSLLVRLSR---DAGFQIVLARHEGGAGYLADGFARASG 63 L+ ++ G+ + G P + + L R + G Q +L RHE GA + ADG+ARA+G Sbjct 18 LIDSLKRHGVQHIFGYPGGAILPIYDELYRAEAEGGIQHILVRHEQGASHAADGYARATG 77 Query 64 KSAAVF-VAGPGATNVISAVANASVNQVPMLILTGEVAVGEFGLHSQQDTSDDGLGLGAT 122 + F +GPGATN+++ +A A ++ +PM+I+TG+VA G + Q+T G+ L Sbjct 78 RVGVCFGTSGPGATNLVTGIATAHMDSIPMVIITGQVARPAIGTDAFQETDIFGITL--- 134 Query 123 FRRFCRCSVSIESIANARSKIDSAFRALASIPRGPVHIALPRDLVDERLPAHQLGTAAAG 182 + S + + + AF ++ RGPV I +P+D+ E + Sbjct 135 --PIVKHSYVVREPGDMARIVAEAFHIASTGRRGPVLIDVPKDVGLEEFDYIPVNPGEVS 192 Query 183 LGGLRTLAPCGPDVADEVIGRLDRSRAPMLVLGNGCRLDGIGEQIVAFCEKAGLPFATTP 242 L G R ++ I ++ + P++ +G G G +I E +P TT Sbjct 193 LPGYRPTVKGNVRQINQAIKLIEEAERPLMYVGGGAISAGAHAEISELAELFQIPVTTTL 252 Query 243 NGRGIVAETHPLSLGVLGIFGDGRADEYLFDTPCDLLIAVGVSFGGLVT---RSFSPRWR 299 G+G E HPLS+G+LG+ G A+ + CDLLIAVG F VT F+ R Sbjct 253 MGKGSFDEKHPLSVGMLGMHGTAYAN--FAVSECDLLIAVGARFDDRVTGKLDEFASR-- 308 Query 300 GLKADVVHVDPDPSAVGRFVATSLGITTSGRAFVNAL-----------NCGRPPRFCRRV 348 A V+H+D DP+ VG+ + I R + L N + + R+ Sbjct 309 ---AKVIHIDIDPAEVGKNRTPEVPIVGDVRQVLIDLLRRCREIGDVGNDNQTQSWLERI 365 Query 349 G-VRPPAPAALPGTPQARGESIHPLELMHELDRELAPNATICADVGTCISWTFRGIPVRR 407 R P +P + +S+ P E++ EL + +AP+A DVG W + + Sbjct 366 NRWREDYPLVVP----SYSDSLSPQEVIAELGK-MAPDAYYTTDVGQHQMWAAQFLK-NG 419 Query 408 PGRFFATVDFSPMGCGIAGAIGVALARPEEHVICIAGDGAFLMHGTEISTAVAHGIRVTW 467 P ++ ++ MG GI A+G +A + VICIAGD + M+ E++T +GI V Sbjct 420 PRQWISSAGLGTMGYGIPSAMGAKVALSDREVICIAGDASVQMNIQELATIAQYGINVKT 479 Query 468 AVLND---GQMSASAGPVSGRMDPSPVARIGANDLAAMARALGAEGIRVDTRCELRAGVQ 524 ++N+ G + G + IG D +AR+ G +G+ V +R EL + Sbjct 480 VIINNGWQGMVRQWQQAFYGERYSASNMEIGMPDFEMLARSYGVKGMVVKSRDELHQALA 539 Query 525 KALAATGPCVLDIAIDPEIN 544 + LA GP ++D+ + + N Sbjct 540 EMLAYEGPVLMDVHVTKDEN 559 >gi|124485430|ref|YP_001030046.1| acetolactate synthase, large subunit [Methanocorpusculum labreanum Z] gi|124362971|gb|ABN06779.1| acetolactate synthase, large subunit [Methanocorpusculum labreanum Z] Length=567 Score = 213 bits (542), Expect = 7e-53, Method: Compositional matrix adjust. Identities = 150/538 (28%), Positives = 254/538 (48%), Gaps = 14/538 (2%) Query 7 LVARMRAAGISVVCGLPTSRLDSLLVRLSRDAGFQIVLARHEGGAGYLADGFARASGKSA 66 L+ ++ G+ ++ G P + + L DA +L RHE A + ADG+ARASG+ Sbjct 10 LIESLKEEGVDIIFGYPGGSVLPIYDEL-YDAELTHILVRHEQAAVHAADGYARASGRVG 68 Query 67 AVF-VAGPGATNVISAVANASVNQVPMLILTGEVAVGEFGLHSQQDTSDDGLGLGATFRR 125 +GPGA N+IS +A A+++ VP++ LTG+V G G + Q++ G+ L T Sbjct 69 VCLSTSGPGACNLISGIATANMDSVPIVALTGQVPTGMLGNDAFQESDITGITLPITKHN 128 Query 126 FCRCSVSIESIANARSKIDSAFRALASIPRGPVHIALPRDLVDERLPAHQLGTAAAGLGG 185 + ++ + + + +AF + GPV I LP+D++ ++ ++ + L G Sbjct 129 YL-----VKDARDIKMTVKAAFYIAGTGRNGPVLIDLPKDVLTAKVAEEEVLSGEPELRG 183 Query 186 LRTLAPCGPDVADEVIGRLDRSRAPMLVLGNGCRLDGIGEQIVAFCEKAGLPFATTPNGR 245 + + + + +++ P+L +G G G E++V E LP TT G Sbjct 184 YKPTLKGHSKQIKKALDLIYKAKKPVLYVGGGVITSGASEELVKLAELFCLPVTTTMMGL 243 Query 246 GIVAETHPLSLGVLGIFGDGRADEYLFDTPCDLLIAVGVSFGGLVTRSFSPRWRGLKADV 305 G + HPL+LG+LG+ G A+ + + DLLIAVG F VT S A V Sbjct 244 GAIPADHPLNLGMLGMHGTEYANYAV--SEADLLIAVGARFDDRVTGKLSHF--ATHAKV 299 Query 306 VHVDPDPSAVGRFVATSLGITTSGRAFVNALNCGRPPRFCRRVGVRPPAPAALPGTPQAR 365 +H+D DP+ +G+ V + I ++ + + C C P Sbjct 300 IHIDIDPAEIGKNVNPDVPIVGDAKSVLADMICLAENNGCISEPWLEQVKLWRTNHPLRV 359 Query 366 GE--SIHPLELMHELDRELAPNATICADVGTCISWTFRGIPVRRPGRFFATVDFSPMGCG 423 E +HP ++ +L L I ++VG W + ++P ++ ++ MG G Sbjct 360 VEDGKVHPQNIIKKLSELLDGGGIIVSEVGQNQMWAAQHYGFKKPRQWISSGGLGTMGYG 419 Query 424 IAGAIGVALARPEEHVICIAGDGAFLMHGTEISTAVAHGIRVTWAVLNDGQMSASAGPVS 483 AIG A+PEE V+ IAGDG+F M+ E++T + I V +LN+ + Sbjct 420 FPAAIGAWFAKPEETVVLIAGDGSFQMNIQELATVAQYKIPVKIVILNNMYLGMVRQWQE 479 Query 484 GRMD-PSPVARIGANDLAAMARALGAEGIRVDTRCELRAGVQKALAATGPCVLDIAID 540 D + A D +A+A G +G++VD+ ++ A +Q AL GP +LD I+ Sbjct 480 LFYDRRYSYTELPAVDFVGIAKAYGIQGMKVDSVDQIDAALQTALDYNGPYLLDFQIE 537 >gi|167045506|gb|ABZ10159.1| putative Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain protein [uncultured marine microorganism HF4000_APKG10H11] Length=556 Score = 213 bits (542), Expect = 8e-53, Method: Compositional matrix adjust. Identities = 156/554 (29%), Positives = 260/554 (47%), Gaps = 36/554 (6%) Query 7 LVARMRAAGISVVCGLPTSRLDSLLVRLSRDAGFQIVLARHEGGAGYLADGFARASGK-S 65 ++ + G+ + G P + + L D+ + +L RHE A + ADG+ARASGK Sbjct 7 IIKSLEQQGVKHIFGHPGGAILDVYDAL-YDSDIEHILVRHEQCAAHAADGYARASGKIG 65 Query 66 AAVFVAGPGATNVISAVANASVNQVPMLILTGEVAVGEFGLHSQQDTSDDGLGLGATFRR 125 + +GPGATN+++ +A A+ + P++ +TG+V G + Q++ L L T Sbjct 66 VCMATSGPGATNLLTGIATANADSSPIIAITGQVPTSLMGADAFQESDAISLTLPIT--- 122 Query 126 FCRCSVSIESIANARSKIDSAFRALASIPRGPVHIALPRDLVDERLPAHQLGTAAAGLGG 185 + ++ ++ N K+ AF +GPVH+ +P+D+ + + Sbjct 123 --KYNMLLDDPKNIHVKLKEAFEIAFDGRQGPVHVDIPKDIQQAEVTI----DFSKSKPK 176 Query 186 LRTL-APCGPDVADEVIGRLDRSRAPMLVLGNGCRLDGIGEQIVAFCEKAGLPFATTPNG 244 + T+ P DV + + L+ R P++ G G L E + E P T+ G Sbjct 177 INTIPEPNLNDVKNAIELLLNAER-PVIYAGGGVILSNASELLTKLAEALMAPVVTSIRG 235 Query 245 RGIVAETHPLSLGVLGIFGDGRADEYLFDTPCDLLIAVGVSFGGLVTRSFSPRWRGLKAD 304 +G + ETH LS+G++G+ G A++ + D+ C ++ +G F T +S + G +A Sbjct 236 KGAIPETHHLSMGMIGMHGSKFANKVISDSDC--ILGIGARFSDRSTYYYSSDF-GERAK 292 Query 305 VVHVDPDPSAVGRFVATSLGITTSGRAFVNAL------------NCGRPPRFCRRVGVRP 352 ++HVD DPS +G+ V T + I TS V + N R + + P Sbjct 293 IIHVDVDPSEIGKNVPTDVQIITSAEKAVKMMLDVLKIQAVKPKNTVWHQRIQQIRKLNP 352 Query 353 PAPAALPGTPQARGESIHPLELMHELDRELAPNATICADVGTCISWTFRGIPVRRPGRFF 412 P P I P ++ E+ L + + A+VG C W P+R+P Sbjct 353 PIKDDYNDVP------IKPPRIIKEIREILGEDDIVTAEVGQCEMWAAMLYPIRKPRTMI 406 Query 413 ATVDFSPMGCGIAGAIGVALARPEEHVICIAGDGAFLMHGTEISTAVAHGIRVTWAVLND 472 + MG G AIG +A+P+ +V+ IAGDG+ LM EISTAV H I V V+N+ Sbjct 407 ISTGMGTMGFGYPAAIGAKVAKPDRNVVDIAGDGSLLMVCQEISTAVNHDIPVVAVVINN 466 Query 473 GQMSASAGPVSGRMDP--SPVARIGANDLAAMARALGAEGIRVDTRCELRAGVQKALAAT 530 + D S V D +A A GA GIRV+ ++R +++AL+A Sbjct 467 RYLGLVRQWQELFYDKHYSGVDLGDKTDFVKLAEAFGAGGIRVEKPEDIRPAIKQALSAD 526 Query 531 GPCVLDIAIDPEIN 544 P ++D+ ++ E N Sbjct 527 IPYIVDVIVEKEFN 540 >gi|11467754|ref|NP_050806.1| acetohydroxyacid synthase large subunit [Guillardia theta] gi|6016364|sp|O78518.1|ILVB_GUITH RecName: Full=Acetolactate synthase large subunit; Short=AHAS; AltName: Full=Acetohydroxy-acid synthase large subunit; Short=ALS gi|3603079|gb|AAC35740.1| acetohydroxyacid synthetase large subunit [Guillardia theta] Length=575 Score = 212 bits (539), Expect = 2e-52, Method: Compositional matrix adjust. Identities = 151/524 (29%), Positives = 244/524 (47%), Gaps = 30/524 (5%) Query 31 LVRLSRDAGFQIVLARHEGGAGYLADGFARASGKSAAVF-VAGPGATNVISAVANASVNQ 89 L ++ + +L RHE GA + +DG+AR++G F +GPGATN+++ +A A ++ Sbjct 43 LYAWEKEGFIEHILVRHEQGAAHASDGYARSTGNVGVCFATSGPGATNLVTGIATAHMDS 102 Query 90 VPMLILTGEVAVGEFGLHSQQDTSDDGLGLGATFRRFCRCSVSIESIANARSKIDSAFRA 149 VPM+I+TG+V G + Q+ G+ L + V E+ + +S F A Sbjct 103 VPMVIITGQVGRSFIGTDAFQEVDIFGITLPIVKHSY----VVRETKEMGKIVAESFFIA 158 Query 150 LASIPRGPVHIALPRDLVDERLPAHQLGTAAAGLGGLRTLAPCGPDVADEVIGRLDRSRA 209 P GPV I +P+D+ E+ + L G L + + + +S Sbjct 159 KYGRP-GPVLIDIPKDVGLEKFDYQIVNPNNINLAGCPVLKNYDQNRISQAANLIKQSSQ 217 Query 210 PMLVLGNGCRLDGIGEQIVAFCEKAGLPFATTPNGRGIVAETHPLSLGVLGIFGDGRADE 269 P+L +G G +I +P ATT G+GI+ E+HPLSLG+LG+ G A+ Sbjct 218 PLLYIGGGAVTSNSHNEINELINLVKIPVATTLMGKGIIDESHPLSLGMLGMHGTVYANY 277 Query 270 YLFDTPCDLLIAVGVSFGGLVTRSFSPRWRGLKADVVHVDPDPSAVGRFVATSLGITTSG 329 + + CDLLIA+G F VT A V+HVD DP+ +G+ +GI Sbjct 278 AV--SECDLLIALGARFDDRVTGKLDE--FACHAQVIHVDIDPAEIGKNRTPQIGIVGEI 333 Query 330 RAFV--------NALNCGRPPRFCRR---VGVRPPAPAALPGTPQARGESIHPLELMHEL 378 + FV N +N R + R P +P ++ P E++HE+ Sbjct 334 KDFVRDLIECLKNDINFDSEQSQAWRSRIIRWRKEYPLLVPKNIN----NLSPQEVIHEI 389 Query 379 DRELAPNATICADVGTCISWTFRGIPVRRPGRFFATVDFSPMGCGIAGAIGVALARPEEH 438 E A NA DVG W + I + R+ + MG G+ AIGV +A P E Sbjct 390 STE-ATNAYFTTDVGQHQMWAAQFIKTSQK-RWITSAGLGTMGYGLPAAIGVQIAHPNEQ 447 Query 439 VICIAGDGAFLMHGTEISTAVAHGIRVTWAVLND---GQMSASAGPVSGRMDPSPVARIG 495 VICI+GD +F M+ E+ T +G+ + ++N+ G + G G Sbjct 448 VICISGDASFQMNIQELGTVSQYGLPIKIFIINNKWQGMVRQWQQAFYGERYSHSNMEKG 507 Query 496 ANDLAAMARALGAEGIRVDTRCELRAGVQKALAATGPCVLDIAI 539 A + +A A G +++ +R +L+ +++AL GP ++DI + Sbjct 508 APNFTKVAEAFGLRSLKIKSRNDLKLRIKEALDYDGPILVDIQV 551 >gi|330506659|ref|YP_004383087.1| acetolactate synthase, large subunit [Methanosaeta concilii GP6] gi|328927467|gb|AEB67269.1| acetolactate synthase, large subunit [Methanosaeta concilii GP6] Length=599 Score = 211 bits (538), Expect = 2e-52, Method: Compositional matrix adjust. Identities = 172/569 (31%), Positives = 262/569 (47%), Gaps = 77/569 (13%) Query 7 LVARMRAAGISVVCGLPTSRLDSLLVRLSRDAGFQIVLARHEGGAGYLADGFARASGK-S 65 ++ ++ G+ VV GLP L L + + + + +L RHE GA ++ADG+ARA+GK Sbjct 26 VLESLKREGVDVVFGLPGGVLLPLYDAIYK-SDIRHILVRHEQGAAHMADGYARATGKVG 84 Query 66 AAVFVAGPGATNVISAVANASVNQVPMLILTGEVAVGEFGLHSQQDTSDDGLGLGATFRR 125 + +GPGATN+++ +ANA ++ VPM+ +TG+V G + Q+ G+ L T Sbjct 85 VCIATSGPGATNLVTGIANAYMDSVPMVAITGQVNTWLIGKDAFQEADITGITLPITKHN 144 Query 126 FCRCSVSIESIANARSKIDSAFRALASIPR----GPVHIALPRDL-VDERLPAHQLGTAA 180 + + + +I FR I R GPV I LPRD+ VDE + Sbjct 145 Y---------LIRSAKEIPGVFREAFYIARTGRPGPVLIDLPRDVTVDELV----FTWPD 191 Query 181 AGLGGLRTLAPCGPDVADEVIGRLDRSRAPMLVLGNGCRLDGIGEQIVAFCEKAGLPFAT 240 L G + L + P++ G G R +++ K P T Sbjct 192 VDLPGYHPSFKAHEMQIKKAAKALMEAERPVIYAGGGVRYASAHKELFELARKVNAPVTT 251 Query 241 TPNGRGIVAETHPLSLGVLGIFGDGRADEYLFDTPCDLLIAVGVSFGGLVT---RSFSPR 297 T G G E HPLSLG+LG+ G A+ + ++ DLL+A+G F VT SF+P Sbjct 252 TLMGVGCFPEDHPLSLGMLGMHGTKYANYAIQES--DLLMAIGARFDDRVTGKISSFAPH 309 Query 298 WRGLKADVVHVDPDPSAVGRFVATSLGITTSGRAFVNALNCGRPPRFCRRVGVRPPAP-- 355 R +VH+D DP+ VG+ V + + R NAL + V +P P Sbjct 310 AR-----IVHIDVDPAEVGKNVRVDIPVVGDAR---NALQG-----LLKEVSPKPKGPWL 356 Query 356 AALPGTPQARGESIHPLELMHELDR-----------ELAPNATICADVGTCISWTFRGIP 404 + G + HP+ + +++ ELAP+A I +VG W + Sbjct 357 EKIDGWKKD-----HPMRYIPDMNLIKPQYVIEKLCELAPDAIITTEVGQNQMWAAQFFV 411 Query 405 VRRPGRFFATVDFSPMGCGIAGAIGVALARPEEHVICIAGDGAFLMHGTEISTAVAHGIR 464 + P RF ++ MG G AIG + RPE VI +AGDG+FLM+ E++TAV + I Sbjct 412 HKDPQRFISSGGLGTMGYGFPAAIGAKMGRPECTVIDVAGDGSFLMNSQELATAVVNDIP 471 Query 465 VTWAVLNDGQM------------SASAGPVSGRMDPSPVARIGANDLAAMARALGAEGIR 512 V AVLN+G + + + GR P D +A A GA G+R Sbjct 472 VKVAVLNNGCLGMVRQWQELFFEKRYSATILGRTSP---------DFVKLAEAYGAVGLR 522 Query 513 VDTRCELRAGVQKALAATGPCVLDIAIDP 541 E+ ++ ALA PCV+D ++P Sbjct 523 ATKPSEVEDVIRSALATDRPCVMDFIVNP 551 >gi|282900124|ref|ZP_06308081.1| Acetolactate synthase, large subunit, biosynthetic type [Cylindrospermopsis raciborskii CS-505] gi|281195006|gb|EFA69946.1| Acetolactate synthase, large subunit, biosynthetic type [Cylindrospermopsis raciborskii CS-505] Length=628 Score = 210 bits (534), Expect = 6e-52, Method: Compositional matrix adjust. Identities = 164/557 (30%), Positives = 259/557 (47%), Gaps = 35/557 (6%) Query 7 LVARMRAAGISVVCGLPTSRLDSL---LVRLSRDAGFQIVLARHEGGAGYLADGFARASG 63 L+ + G+ + G P + + L ++ + +L RHE GA + ADG+ARA+G Sbjct 36 LLDSLLRHGVEYIFGYPGGAILPIYDDLYKVEETGSIKHILVRHEQGASHAADGYARATG 95 Query 64 KSAAVF-VAGPGATNVISAVANASVNQVPMLILTGEVAVGEFGLHSQQDTSDDGLGLGAT 122 K F +GPGATN+++ +A A ++ +PM+I+TG+V G + Q+T G+ L Sbjct 96 KVGVCFGTSGPGATNLVTGIATAYMDSIPMIIVTGQVPRPAIGTDAFQETDIYGITL--- 152 Query 123 FRRFCRCSVSIESIANARSKIDSAFRALASIPR-GPVHIALPRDLVDERLPAHQLGTAAA 181 + S + + + AF LAS R GPV I +P+D+ E+ + + Sbjct 153 --PIVKHSYVVRDPKDMARIVAEAFH-LASTGRPGPVLIDVPKDVALEKFDYTPVEPGSV 209 Query 182 GLGGLRTLAPCGPDVADEVIGRLDRSRAPMLVLGNGCRLDGIGEQIVAFCEKAGLPFATT 241 L G R P + I + SR P+L +G G G ++I E +P TT Sbjct 210 KLPGYRPTVKGNPRQINAAIQLITESRKPLLYVGGGAIASGSHKEIKELAELFNIPVTTT 269 Query 242 PNGRGIVAETHPLSLGVLGIFGDGRADEYLFDTPCDLLIAVGVSFGGLVTRSFSPRWRGL 301 G G E HPLSLG+LG+ G A+ + D CDLLI VG F VT Sbjct 270 LMGIGAFDEHHPLSLGMLGMHGTAYANFAVTD--CDLLICVGARFDDRVTGKLDE--FAS 325 Query 302 KADVVHVDPDPSAVGRFVATSLGITTSGRAFVNAL----------NCGRPPRFCRRVG-V 350 A V+H+D DP+ VG+ + I + + L + R + +G Sbjct 326 HAKVIHIDIDPAEVGKNRVPEVPIVGDVKNVLEDLLRRCHNNHHNHHNRNQEWLNLIGRW 385 Query 351 RPPAPAALPGTPQARGESIHPLELMHELDRELAPNATICADVGTCISWTFRGIPVRRPGR 410 + P +P P +SI P E++ E+ ++ APNA DVG W + + P R Sbjct 386 KQDYPLIVPHYP----DSISPQEVIVEIGKQ-APNAIYTTDVGQHQMWAAQFLK-NGPRR 439 Query 411 FFATVDFSPMGCGIAGAIGVALARPEEHVICIAGDGAFLMHGTEISTAVAHGIRVTWAVL 470 + ++ MG G+ A+G +A PEE VICI+GD +F M E+ T +GI V +L Sbjct 440 WISSAGLGTMGFGVPAAMGAKVAFPEEEVICISGDASFQMCLQELGTLAQYGINVKTVIL 499 Query 471 ND---GQMSASAGPVSGRMDPSPVARIGANDLAAMARALGAEGIRVDTRCELRAGVQKAL 527 N+ G + G +G D+ +A+A G +G+ + + EL V + L Sbjct 500 NNGWQGMVRQWQEAFYGERYSCSNMEVGMPDIELLAQAYGIKGMVITKQEELSQKVAEML 559 Query 528 AATGPCVLDIAIDPEIN 544 GP V+++ + + N Sbjct 560 EHKGPVVVNVHVTKDEN 576 >gi|119509049|ref|ZP_01628200.1| acetolactate synthase III large subunit [Nodularia spumigena CCY9414] gi|119466215|gb|EAW47101.1| acetolactate synthase III large subunit [Nodularia spumigena CCY9414] Length=632 Score = 210 bits (534), Expect = 6e-52, Method: Compositional matrix adjust. Identities = 157/535 (30%), Positives = 244/535 (46%), Gaps = 41/535 (7%) Query 31 LVRLSRDAGFQIVLARHEGGAGYLADGFARASGKSAAVF-VAGPGATNVISAVANASVNQ 89 L ++ + +L RHE GA + ADG+ARA+GK F +GPGATN+++ +A A ++ Sbjct 66 LYKVESTGAIKHILVRHEQGAAHAADGYARATGKVGVCFGTSGPGATNLVTGIATAYMDS 125 Query 90 VPMLILTGEVAVGEFGLHSQQDTSDDGLGLGATFRRFCRCSVSIESIANARSKIDSAFRA 149 +PM+++TG+V G + Q+T G+ L + S + + + AF Sbjct 126 IPMIVVTGQVPRASIGTDAFQETDIYGITL-----PIVKHSYVVRDPKDMARIVAEAFHI 180 Query 150 LASIPRGPVHIALPRDLVDERLPAHQLGTAAAGLGGLRTLAPCGPDVADEVIGRLDRSRA 209 ++ GPV I +P+D+ E + L G R P + I + S Sbjct 181 ASTGRPGPVLIDVPKDVALEECDYVPVARGTVKLPGYRPTVKGNPRQINAAIKLIRNSHR 240 Query 210 PMLVLGNGCRLDGIGEQIVAFCEKAGLPFATTPNGRGIVAETHPLSLGVLGIFGDGRADE 269 P+L +G G +I E +P TT G G E HPLS+G+LG+ G A+ Sbjct 241 PLLYVGGGAIASNAHAEIKELAELFNIPVTTTLMGIGAFDEHHPLSVGMLGMHGTAYANF 300 Query 270 YLFDTPCDLLIAVGVSFGGLVTRSFSPRWRGLKADVVHVDPDPSAVGRFVATSLGITTSG 329 + D CDLLI VG F VT A V+H+D DP+ VG+ + I Sbjct 301 AVTD--CDLLICVGARFDDRVTGKLDEF--ASHAKVIHIDIDPAEVGKNRVPEVPIVGDV 356 Query 330 RAFVNALNCGRPPRFCRRVGV-----------------RPPAPAALPGTPQARGESIHPL 372 R + L R C+ G+ R P +P P +SI P Sbjct 357 RQVLVDLL-----RRCQETGIKNIPHKNQEWLHLINRWRQDYPLEVPQHP----DSISPQ 407 Query 373 ELMHELDRELAPNATICADVGTCISWTFRGIPVRRPGRFFATVDFSPMGCGIAGAIGVAL 432 E++ E+ R+ AP+A DVG W + + P R+ ++ MG G+ A+G + Sbjct 408 EVIVEVGRQ-APHAFYTTDVGQHQMWAAQFLK-NGPRRWISSAGLGTMGFGVPAAMGAKV 465 Query 433 ARPEEHVICIAGDGAFLMHGTEISTAVAHGIRVTWAVLND---GQMSASAGPVSGRMDPS 489 A P+E VICI+GD +F M E+ T +GI V +LN+ G + G Sbjct 466 AFPDEEVICISGDASFQMCLQELGTLAQYGINVKTVILNNGWQGMVRQWQQAFYGERYSC 525 Query 490 PVARIGANDLAAMARALGAEGIRVDTRCELRAGVQKALAATGPCVLDIAIDPEIN 544 +G D+ + +A G +G+ V TR EL+ + + LA GP V+D+ + + N Sbjct 526 SNMEVGMPDIEHLTKAYGIKGMVVQTREELQGAIAEMLAHNGPVVMDVRVTKDEN 580 >gi|300865814|ref|ZP_07110564.1| acetolactate synthase 3 catalytic subunit [Oscillatoria sp. PCC 6506] gi|300336180|emb|CBN55719.1| acetolactate synthase 3 catalytic subunit [Oscillatoria sp. PCC 6506] Length=616 Score = 210 bits (534), Expect = 6e-52, Method: Compositional matrix adjust. Identities = 170/575 (30%), Positives = 265/575 (47%), Gaps = 56/575 (9%) Query 2 TVGDHLVARMRAAGISVVCGLPTSRLDSLLVRLSR---DAGFQIVLARHEGGAGYLADGF 58 T G L+ +R G+ + G P + + L R + G Q +L RHE GAG+ ADG+ Sbjct 13 TGGFALIDSLRRHGVKHIFGYPGGAILPIYDELYRAEAEGGIQHILVRHEQGAGHAADGY 72 Query 59 ARASGKSAAVF-VAGPGATNVISAVANASVNQVPMLILTGEVAVGEFGLHSQQDTSDDGL 117 ARA+G+ F +GPGATN+++A+A A ++ +PM+I+TG+V G + Q+T G+ Sbjct 73 ARATGQVGVCFGTSGPGATNLVTAIATAQMDSIPMVIVTGQVPRSAIGSDAFQETDIYGI 132 Query 118 GLGATFRRFCRCSVSIESIANARSKIDSAFRALASIPRGPVHIALPRDLVDERLPAHQLG 177 L + S + + + AF + GPV I +P+D+ E + Sbjct 133 TLP-----IVKHSYVVRDPRDMAKIVAEAFHIAITGRPGPVLIDVPKDVGLEEFDYIPVA 187 Query 178 TAAAGLGGLRTLAPCGPDVADEVIGRLDRSRAPMLVLGNGCRLDGIGEQIVAFCEKAGLP 237 A + G R P ++ + + ++ P+L +G G G +I + +P Sbjct 188 PGAVRIPGYRPTVKGNPRQINQAVNLIRQAERPLLYVGGGAIAAGAHAEIQELAQLFQIP 247 Query 238 FATTPNGRGIVAETHPLSLGVLGIFGDGRADEYLFDTPCDLLIAVGVSFGGLVT---RSF 294 TT G+G E HPLSL +LG+ G A+ + T CDLLIAVG F VT F Sbjct 248 VTTTLMGKGAFDEKHPLSLKMLGMHGTAYANFAV--TECDLLIAVGARFDDRVTGKLDEF 305 Query 295 SPRWRGLKADVVHVDPDPSAVGRFVATSLGIT---------------TSGRAFVNALNCG 339 + R A V+H+D DP+ VG+ + I +G +A Sbjct 306 ASR-----AKVIHIDIDPAEVGKNRPPEVPIVGDVRNVLIDLLRRCRETGEVNRDASGTD 360 Query 340 RPPRFCRRVG-VRPPAPAALPGTPQARGESIHPLELMHELDRELAPNATICADVGTCISW 398 R + R+ + P +P P + I P E++ ELDR+ AP+A DVG W Sbjct 361 RTQEWLARINRWKQDYPLEVPHYP----DVISPQEVIVELDRQ-APDAYFTTDVGQHQMW 415 Query 399 TFRGIPVRRPGRFFATVDFSPMGCGIAGAIGVALARPEEHVICIAGDGAFLMHGTEISTA 458 + + + P R+ ++ MG G+ A+G +A P E VICIAGD + M+ E+ T Sbjct 416 SAQFLN-NGPRRWISSAGLGTMGYGMPAAMGAKMALPHEQVICIAGDASIQMNIQELGTL 474 Query 459 VAHGIRVTWAVLNDG---------QMSASAGPVSGRMDPSPVARIGANDLAAMARALGAE 509 +GI V ++N+G Q S M PS D +A A G + Sbjct 475 SQYGIAVKTVIVNNGWQGMVRQWQQAFYGERYSSSNMQPS------MPDFVMLAAAYGVK 528 Query 510 GIRVDTRCELRAGVQKALAATGPCVLDIAIDPEIN 544 GI V R +L + + LA GP ++D+ + + N Sbjct 529 GIAVSQRDQLADAIAQMLAHNGPVLMDVKVSRDEN 563 >gi|225181135|ref|ZP_03734581.1| acetolactate synthase, large subunit, biosynthetic type [Dethiobacter alkaliphilus AHT 1] gi|225168104|gb|EEG76909.1| acetolactate synthase, large subunit, biosynthetic type [Dethiobacter alkaliphilus AHT 1] Length=558 Score = 210 bits (534), Expect = 7e-52, Method: Compositional matrix adjust. Identities = 159/551 (29%), Positives = 255/551 (47%), Gaps = 33/551 (5%) Query 7 LVARMRAAGISVVCGLPTSRLDSLLVRLSRDAGFQIVLARHEGGAGYLADGFARASGKSA 66 ++ ++ + V+ G P + +L +L DA + +++RHE GA + ADG++R +G+ Sbjct 9 IIESLKKENVDVIFGYPGGAVLNLYDQLY-DADIRHIMSRHEQGAIHAADGYSRMTGRPG 67 Query 67 AVF-VAGPGATNVISAVANASVNQVPMLILTGEVAVGEFGLHSQQDTSDDGLGLGATFRR 125 VF +GPGATN+++ +A A ++ VPM++ TG+VA G + Q+ G+ L T Sbjct 68 VVFATSGPGATNLVTGIATAYMDSVPMVVFTGQVASPLIGTDAFQEADIFGITLPITKHN 127 Query 126 FCRCSVSIESIANARSKIDSAFRALASIPRGPVHIALPRDL----VDERLPAHQLGTAAA 181 + + + I AF + RGPV I LP+D+ D R P Sbjct 128 YL-----VTDVEELPRIIKEAFYLATTGRRGPVLIDLPKDVQQAVTDYRYPD------KV 176 Query 182 GLGGLRTLAPCGPDVADEVIGRLDRSRAPMLVLGNGCRLDGIGEQIVAFCEKAGLPFATT 241 + G P + R++ P++ G G ++++ EKA +P TT Sbjct 177 EIPGYNPTYEGHPGQITRAAKAIGRAKKPVIYAGGGVVYAEAHQELLTLAEKAQIPVTTT 236 Query 242 PNGRGIVAETHPLSLGVLGIFGDGRADEYLFDTPCDLLIAVGVSFGGLVTRSFSPRWRGL 301 G HPLS+G+LG+ G A+ + + DL+IA+G F VT S + Sbjct 237 LMGLSGFPGNHPLSVGMLGMHGMYWANMAMHE--ADLIIAIGARFDDRVTGKLSHFAK-- 292 Query 302 KADVVHVDPDPSAVGRFVATSLGITTS-GRAFVNALNCGRPPR---FCRRVG-VRPPAPA 356 A ++H+D DP+ +G+ V + + R L P + R+G R P Sbjct 293 NAKIIHIDIDPAEIGKNVKVDIPVVGDVKRVLCEVLKKVEPKNHEDWLARIGEWRKEVPL 352 Query 357 ALPGTPQARGESIHPLELMHELDRELAPNATICADVGTCISWTFRGIPVRRPGRFFATVD 416 G Q I P ++ + +E A I +VG WT + +P F ++ Sbjct 353 ---GYNQEDDSDISPQYVIEMIYQETDGEALITTEVGQHQMWTAQYYKFNKPRSFASSGG 409 Query 417 FSPMGCGIAGAIGVALARPEEHVICIAGDGAFLMHGTEISTAVAHGIRVTWAVLND---G 473 MG G ++G +ARP E V CIAGDG+F M+ E++TAV + I V A++N+ G Sbjct 410 LGTMGYGFPASLGAQVARPGETVFCIAGDGSFQMNSQELATAVEYNIPVKVAIINNQFLG 469 Query 474 QMSASAGPVSGRMDPSPVARIGANDLAAMARALGAEGIRVDTRCELRAGVQKALAATGPC 533 + R S V G D +A A GA G+R + E+ A ++KAL GP Sbjct 470 MVRQWQQMFFKRRYSSVVMEQGP-DFVKLAEAYGATGLRAEKPSEVTAVIKKALETPGPV 528 Query 534 VLDIAIDPEIN 544 V+D + E N Sbjct 529 VMDFRVRAEEN 539 >gi|150391156|ref|YP_001321205.1| acetolactate synthase, large subunit, biosynthetic type [Alkaliphilus metalliredigens QYMF] gi|149951018|gb|ABR49546.1| acetolactate synthase, large subunit, biosynthetic type [Alkaliphilus metalliredigens QYMF] Length=571 Score = 209 bits (532), Expect = 9e-52, Method: Compositional matrix adjust. Identities = 156/562 (28%), Positives = 257/562 (46%), Gaps = 45/562 (8%) Query 7 LVARMRAAGISVVCGLPTSRLDSLLVRLSRDAGFQIVLARHEGGAGYLADGFARASGKSA 66 ++ + GI+++ G+P + L++ Q +LARHE GAG+++ G AR +GK+A Sbjct 10 IIRLLEEQGINIITGIPGGGNLPMYNALAKSTQIQHILARHEQGAGFISQGMARTTGKTA 69 Query 67 AVF-VAGPGATNVISAVANASVNQVPMLILTGEVAVGEFGLHSQQDTSDDGLGLGATFRR 125 F +GPG TN+++A+A+A ++ VP++ +TG+V G + Q+ GL + T Sbjct 70 VCFATSGPGVTNLLTAIADAKLDSVPIVAITGQVPSSFVGTDAFQEVDTCGLAIPITKHN 129 Query 126 FCRCSVSIESIANARSKIDSAFRALASIPRGPVHIALPRD-------------LVDERLP 172 F + S I AF+ +S GPV + +P+D L DE P Sbjct 130 FF-----VRSAQELFHIIPEAFKIASSGRPGPVIVDIPKDVQMAEIELENWPILTDES-P 183 Query 173 AHQLGTAAAGLGGLRTLAPCGPDVADEVIGRLDRSRAPMLVLGNGCRLDGIGEQIVAFCE 232 H G + + D +++ ++ S+ P+ +G G E + + Sbjct 184 LHDNGKKTS----IPNETKISLDEIEKIANMINSSKRPLFYIGGGILQSNSHELLHQLAK 239 Query 233 KAGLPFATTPNGRGIVAETHPLSLGVLGIFGDGRADEYLFDTPCDLLIAVGVSFGGLVT- 291 K +P A+T G G L LG+LG+ G + L +T DLLIA GV F T Sbjct 240 KNHIPVASTLMGLGCFPSKDSLYLGMLGMHGAPYTNLILNET--DLLIAFGVRFDDRATG 297 Query 292 --RSFSPRWRGLKADVVHVDPDPSAVGRFVATSLGITTS----GRAFVNALNCGRPPRFC 345 F P A ++HVD DP+ + + AT + +A + ++ ++ Sbjct 298 NIAKFCP-----DASIIHVDIDPAELDKNKATHFSMAADIGLVLQALIPLIHLDPRSKWI 352 Query 346 RRVG-VRPPAPAALPGTPQARGESIHPLELMHELDRELAPNATICADVGTCISWTFRGIP 404 V ++ P P + HP+ + E+ + + I DVG W + P Sbjct 353 EEVAAIKKANPLYTP----EDNDFYHPVNFIKEISNIVDSDTIITTDVGQHQMWVAQTYP 408 Query 405 VRRPGRFFATVDFSPMGCGIAGAIGVALARPEEHVICIAGDGAFLMHGTEISTAVAHGIR 464 +P + MG G+ AIG ALA P + VICI+GDG+ LM+ E++T H + Sbjct 409 FEKPRTLLTSGGLGTMGFGLPTAIGAALANPTKKVICISGDGSILMNIQELATLADHNLN 468 Query 465 VTWAVLNDGQMSASAGPVSGRMDPSPVARIGAN--DLAAMARALGAEGIRVDTRCELRAG 522 + +LN+G + D + +A + AA+A A G EG + A Sbjct 469 IKVIILNNGCLGLVRQLQEFFFDENYIASSFTTHPNFAAIATAFGIEGFDFKDTKQPIAQ 528 Query 523 VQKALAATGPCVLDIAIDPEIN 544 +QK L+A+GPCV+++ IDP N Sbjct 529 LQKLLSASGPCVINVPIDPREN 550 >gi|218441880|ref|YP_002380209.1| acetolactate synthase 3 catalytic subunit [Cyanothece sp. PCC 7424] gi|218174608|gb|ACK73341.1| acetolactate synthase, large subunit, biosynthetic type [Cyanothece sp. PCC 7424] Length=619 Score = 209 bits (532), Expect = 1e-51, Method: Compositional matrix adjust. Identities = 162/560 (29%), Positives = 262/560 (47%), Gaps = 40/560 (7%) Query 7 LVARMRAAGISVVCGLPTSRLDSL---LVRLSRDAGFQIVLARHEGGAGYLADGFARASG 63 L+ ++ G+ + G P + + L R Q +L RHE GA + ADG+ARA+G Sbjct 25 LMDSLKRHGVKHIFGYPGGAILPIYDELYRFEARGDIQHILVRHEQGAAHAADGYARATG 84 Query 64 KSAAVF-VAGPGATNVISAVANASVNQVPMLILTGEVAVGEFGLHSQQDTSDDGLGLGAT 122 K F +GPGATN+++ +A A ++ +PM+I+TG+V+ G + Q+T G+ L Sbjct 85 KVGVCFGTSGPGATNLVTGIATAHMDSIPMVIITGQVSRPAIGSDAFQETDIFGITLP-- 142 Query 123 FRRFCRCSVSIESIANARSKIDSAFRALASIPRGPVHIALPRDLVDERLPAHQLGTAAAG 182 + S + ++ + AF ++ GPV I +P+D+ E + Sbjct 143 ---IVKHSYVVRQASDMARIVAEAFHIASTGRPGPVLIDVPKDVGLEECDYIPVEPGDVK 199 Query 183 LGGLRTLAPCGPDVADEVIGRLDRSRAPMLVLGNGCRLDGIGEQIVAFCEKAGLPFATTP 242 L G R P + + ++ + P+L +G G QI E+ G+P TT Sbjct 200 LTGYRPTVKGNPRQINAALHLIETAERPLLYVGGGAIAANAHAQIHELAERFGIPVTTTL 259 Query 243 NGRGIVAETHPLSLGVLGIFGDGRADEYLFDTPCDLLIAVGVSFGGLVT---RSFSPRWR 299 G G E HPLS+G+LG+ G A+ + T CDLLIAVG F VT F+ R Sbjct 260 MGLGAFDEHHPLSVGMLGMHGTAYANFAV--TECDLLIAVGARFDDRVTGKLEEFASR-- 315 Query 300 GLKADVVHVDPDPSAVGRFVATSLGITTSGRAFVNALNC-----------GRPPRFCRRV 348 A VVH+D DP+ VG+ A + I R + + R + R+ Sbjct 316 ---AKVVHIDIDPAEVGKVRAPDVPIVGDVRQVLEQMLQRVREMDYPTVPERTKDWLERI 372 Query 349 G-VRPPAPAALPGTPQARGESIHPLELMHELDRELAPNATICADVGTCISWTFRGIPVRR 407 R P +P P +SI P +++ ELDR+ AP A DVG W + + Sbjct 373 NRWREDYPLMVPTYP----DSIAPQQVIVELDRQ-APRAYYTTDVGQHQMWAAQFLK-NG 426 Query 408 PGRFFATVDFSPMGCGIAGAIGVALARPEEHVICIAGDGAFLMHGTEISTAVAHGIRVTW 467 P R+ ++ MG G+ A+G +A +E VICI+GD +F M+ E++T + I+V Sbjct 427 PRRWISSAGLGTMGFGMPAAMGAKVAVSDEEVICISGDASFQMNSQELATLAQYNIKVKT 486 Query 468 AVLND---GQMSASAGPVSGRMDPSPVARIGANDLAAMARALGAEGIRVDTRCELRAGVQ 524 ++N+ G + G S + G + +A+A G +G+ V +L + Sbjct 487 VIINNGWQGMVRQWQQTFYGERYSSSNMQPGMPNFELLAQAYGVKGMTVTDPAQLPDAIA 546 Query 525 KALAATGPCVLDIAIDPEIN 544 + LA GP ++D+ + + N Sbjct 547 EMLAHDGPVLMDVHVRRDEN 566 >gi|282896701|ref|ZP_06304709.1| Acetolactate synthase, large subunit, biosynthetic type [Raphidiopsis brookii D9] gi|281198419|gb|EFA73307.1| Acetolactate synthase, large subunit, biosynthetic type [Raphidiopsis brookii D9] Length=628 Score = 209 bits (531), Expect = 1e-51, Method: Compositional matrix adjust. Identities = 163/557 (30%), Positives = 259/557 (47%), Gaps = 35/557 (6%) Query 7 LVARMRAAGISVVCGLPTSRLDSL---LVRLSRDAGFQIVLARHEGGAGYLADGFARASG 63 L+ + G+ + G P + + L ++ + +L RHE GA + ADG+ARA+G Sbjct 36 LLDSLLRHGVEYIFGYPGGAILPIYDDLYKVEETGTIKHILVRHEQGASHAADGYARATG 95 Query 64 KSAAVF-VAGPGATNVISAVANASVNQVPMLILTGEVAVGEFGLHSQQDTSDDGLGLGAT 122 K F +GPGATN+++ +A A ++ +PM+I+TG+V G + Q+T G+ L Sbjct 96 KVGVCFGTSGPGATNLVTGIATAYMDSIPMIIVTGQVPRPAIGTDAFQETDIYGITL--- 152 Query 123 FRRFCRCSVSIESIANARSKIDSAFRALASIPR-GPVHIALPRDLVDERLPAHQLGTAAA 181 + S + + + AF LAS R GPV I +P+D+ E+ + + Sbjct 153 --PIVKHSYVVRDPKDMARIVAEAFH-LASTGRPGPVLIDVPKDVALEQFDYTPVEPGSV 209 Query 182 GLGGLRTLAPCGPDVADEVIGRLDRSRAPMLVLGNGCRLDGIGEQIVAFCEKAGLPFATT 241 L G R P + I + SR P+L +G G G ++I E +P TT Sbjct 210 KLPGYRPTVKGNPRQVNAAIQLITESRKPLLYVGGGAIASGSHKEIKELAELFNIPVTTT 269 Query 242 PNGRGIVAETHPLSLGVLGIFGDGRADEYLFDTPCDLLIAVGVSFGGLVTRSFSPRWRGL 301 G G E HPLSLG+LG+ G A+ + D CDLLI VG F VT Sbjct 270 LMGIGAFDEHHPLSLGMLGMHGTAYANFAVTD--CDLLICVGARFDDRVTGKLDE--FAS 325 Query 302 KADVVHVDPDPSAVGRFVATSLGITTSGRAFVNAL----------NCGRPPRFCRRVG-V 350 A V+H+D DP+ VG+ + I + + L + R + +G Sbjct 326 HAKVIHIDIDPAEVGKNRVPEVPIVGDVKNVLEDLLRRCHNNHQNHHNRNQEWLNLIGRW 385 Query 351 RPPAPAALPGTPQARGESIHPLELMHELDRELAPNATICADVGTCISWTFRGIPVRRPGR 410 + P +P P +SI P E++ E+ ++ APNA DVG W + + P R Sbjct 386 KQDYPLMVPHYP----DSISPQEVIVEIGKQ-APNAIYTTDVGQHQMWAAQFLK-NGPRR 439 Query 411 FFATVDFSPMGCGIAGAIGVALARPEEHVICIAGDGAFLMHGTEISTAVAHGIRVTWAVL 470 + ++ MG G+ A+G +A PEE VICI+GD +F M E+ T +GI V +L Sbjct 440 WISSAGLGTMGFGVPAAMGAKVAFPEEEVICISGDASFQMCLQELGTLAQYGINVKTVIL 499 Query 471 ND---GQMSASAGPVSGRMDPSPVARIGANDLAAMARALGAEGIRVDTRCELRAGVQKAL 527 N+ G + G +G D+ +A+A G +G+ + + EL + + L Sbjct 500 NNGWQGMVRQWQEAFYGERYSCSNMEVGMPDIELLAQAYGIKGMVITKQEELSLKIAEML 559 Query 528 AATGPCVLDIAIDPEIN 544 GP V+++ + + N Sbjct 560 EHKGPVVVNVHVTKDEN 576 >gi|186682147|ref|YP_001865343.1| acetolactate synthase 3 catalytic subunit [Nostoc punctiforme PCC 73102] gi|186464599|gb|ACC80400.1| acetolactate synthase, large subunit, biosynthetic type [Nostoc punctiforme PCC 73102] Length=637 Score = 208 bits (530), Expect = 2e-51, Method: Compositional matrix adjust. Identities = 165/566 (30%), Positives = 263/566 (47%), Gaps = 52/566 (9%) Query 7 LVARMRAAGISVVCGLPTSRLDSL---LVRLSRDAGFQIVLARHEGGAGYLADGFARASG 63 L+ + G+ + G P + + L ++ + +L RHE GA + ADG+ARA+G Sbjct 44 LLDSLHRHGVDYIFGYPGGAILPIYDDLYKVEATGAIKHILVRHEQGAAHAADGYARATG 103 Query 64 KSAAVF-VAGPGATNVISAVANASVNQVPMLILTGEVAVGEFGLHSQQDTSDDGLGLGAT 122 K F +GPGATN+++ +A A ++ +PM+++TG+VA G + Q+T G+ L Sbjct 104 KVGVCFGTSGPGATNLVTGIATAYMDSIPMIVVTGQVARPSIGTDAFQETDIYGITLP-- 161 Query 123 FRRFCRCSVSIESIANARSKIDSAFRALASIPRGPVHIALPRDLVDERLPAHQLGTAAAG 182 + S + + + AF ++ GPV I +P+D+ E + + Sbjct 162 ---IVKHSYVVRDPKDMARIVAEAFHIASTGRPGPVLIDVPKDVALEEFDYVPVKPGSVK 218 Query 183 LGGLRTLAPCGPDVADEVIGRLDRSRAPMLVLGNGCRLDGIGEQIVAFCEKAGLPFATTP 242 L G R P + I + SR P+L +G G G E+I E +P TT Sbjct 219 LRGYRPTVKGNPRQINAAIQLITESRRPLLYIGGGAIAAGAHEEIKELAELFNIPVTTTL 278 Query 243 NGRGIVAETHPLSLGVLGIFGDGRADEYLFDTPCDLLIAVGVSFGGLVT---RSFSPRWR 299 G G E HPL+LG+LG+ G A+ + D CDLLI VG F VT F+ R Sbjct 279 MGIGAFDEHHPLALGMLGMHGTAYANFAVSD--CDLLICVGARFDDRVTGKLDEFASR-- 334 Query 300 GLKADVVHVDPDPSAVGRFVATSLGITTSGR-AFVNALNCGRPPRFCRRVGV-------- 350 A V+H+D DP+ VG+ + I R V+ L R C+ GV Sbjct 335 ---AKVIHIDIDPAEVGKNRIPEVPIVGDVRNVLVDLL------RRCKETGVKATPNQNQ 385 Query 351 ---------RPPAPAALPGTPQARGESIHPLELMHELDRELAPNATICADVGTCISWTFR 401 R P +P P +SI P E++ E++ + APNA DVG W + Sbjct 386 EWLNLVNRWRDEYPLIVPQHP----DSISPQEVIVEVNSQ-APNAFYTTDVGQHQMWAAQ 440 Query 402 GIPVRRPGRFFATVDFSPMGCGIAGAIGVALARPEEHVICIAGDGAFLMHGTEISTAVAH 461 + P R+ ++ MG G+ A+G +A P+E VICI+GD +F M E+ T + Sbjct 441 FLK-NGPRRWISSAGLGTMGFGLPAAMGAKVAFPDEEVICISGDASFQMCLQELGTLAQY 499 Query 462 GIRVTWAVLND---GQMSASAGPVSGRMDPSPVARIGANDLAAMARALGAEGIRVDTRCE 518 GI V ++N+ G + G +G D+ +A+A G +G+ + R + Sbjct 500 GINVKTIIINNGWQGMVRQWQQAFYGERYSCSNMEVGMPDVELLAKAYGIKGMVISDRSQ 559 Query 519 LRAGVQKALAATGPCVLDIAIDPEIN 544 L+ + + LA GP +L++ + + N Sbjct 560 LKDAIAEMLAHKGPVILNVHVTRDEN 585 >gi|209523765|ref|ZP_03272318.1| acetolactate synthase, large subunit, biosynthetic type [Arthrospira maxima CS-328] gi|209495797|gb|EDZ96099.1| acetolactate synthase, large subunit, biosynthetic type [Arthrospira maxima CS-328] Length=612 Score = 208 bits (529), Expect = 2e-51, Method: Compositional matrix adjust. Identities = 161/569 (29%), Positives = 264/569 (47%), Gaps = 41/569 (7%) Query 7 LVARMRAAGISVVCGLPTSRLDSLLVRLSR---DAGFQIVLARHEGGAGYLADGFARASG 63 L+ ++ G+ + G P + + L R + Q +L RHE GA + ADG+ARA+G Sbjct 18 LIDSLKRHGVQHIFGYPGGAILPIYDELYRAEAEGDIQHILVRHEQGASHAADGYARATG 77 Query 64 KSAAVF-VAGPGATNVISAVANASVNQVPMLILTGEVAVGEFGLHSQQDTSDDGLGLGAT 122 + F +GPGATN+++ +A A ++ +PM+I+TG+VA G + Q+T G+ L Sbjct 78 RVGVCFGTSGPGATNLVTGIATAHMDSIPMVIITGQVARPAIGTDAFQETDIFGITL--- 134 Query 123 FRRFCRCSVSIESIANARSKIDSAFRALASIPRGPVHIALPRDLVDERLPAHQLGTAAAG 182 + S + + + AF ++ GPV I +P+D+ E + Sbjct 135 --PIVKHSYVVREPGDMARIVAEAFHIASTGRPGPVLIDVPKDVGLEEFDYIPVNPGEVS 192 Query 183 LGGLRTLAPCGPDVADEVIGRLDRSRAPMLVLGNGCRLDGIGEQIVAFCEKAGLPFATTP 242 L G R ++ I ++ + P++ +G G G +I E +P TT Sbjct 193 LPGYRPTVKGNVRQINQAIKLIEEAERPLMYVGGGAISAGAHAEIAELAELFQIPVTTTL 252 Query 243 NGRGIVAETHPLSLGVLGIFGDGRADEYLFDTPCDLLIAVGVSFGGLVT---RSFSPRWR 299 G+G E HPLS+G+LG+ G A+ + CDLLIAVG F VT F+ R Sbjct 253 MGKGSFDEKHPLSVGMLGMHGTAYAN--FAVSECDLLIAVGARFDDRVTGKLDEFASR-- 308 Query 300 GLKADVVHVDPDPSAVGRFVATSLGITTSGRAFVNAL-----------NCGRPPRFCRRV 348 A V+H+D DP+ VG+ + I R + L N + + R+ Sbjct 309 ---AKVIHIDIDPAEVGKNRTPEVPIVGDVRQVLIDLLRRCREIGDVGNDNQTQSWLERI 365 Query 349 G-VRPPAPAALPGTPQARGESIHPLELMHELDRELAPNATICADVGTCISWTFRGIPVRR 407 R P +P + +S+ P E++ EL + +AP+A DVG W + + Sbjct 366 NRWREDYPLVVP----SYSDSLSPQEVIAELGK-MAPDAYYTTDVGQHQMWAAQFLK-NG 419 Query 408 PGRFFATVDFSPMGCGIAGAIGVALARPEEHVICIAGDGAFLMHGTEISTAVAHGIRVTW 467 P ++ ++ MG GI A+G +A + VICIAGD + M+ E+ T +GI V Sbjct 420 PRQWISSAGLGTMGYGIPSAMGAKVALSDREVICIAGDASVQMNIQELGTIAQYGINVKT 479 Query 468 AVLND---GQMSASAGPVSGRMDPSPVARIGANDLAAMARALGAEGIRVDTRCELRAGVQ 524 ++N+ G + G + IG D +AR+ G +G+ V +R EL + Sbjct 480 VIINNGWQGMVRQWQQAFYGERYSASNMEIGMPDFEMLARSYGVKGMVVKSRDELHQALA 539 Query 525 KALAATGPCVLDIAIDPEIN-KPDIGLGR 552 + LA GP ++D+ + + N P + GR Sbjct 540 EMLAYEGPVLMDVHVTKDENCYPMVAPGR 568 >gi|332710392|ref|ZP_08430340.1| acetolactate synthase, large subunit [Lyngbya majuscula 3L] gi|332350941|gb|EGJ30533.1| acetolactate synthase, large subunit [Lyngbya majuscula 3L] Length=619 Score = 208 bits (529), Expect = 2e-51, Method: Compositional matrix adjust. Identities = 160/557 (29%), Positives = 267/557 (48%), Gaps = 34/557 (6%) Query 7 LVARMRAAGISVVCGLPTSRLDSLLVRLS--RDAG-FQIVLARHEGGAGYLADGFARASG 63 L+ + G++ + G P + + L DAG Q +L RHE GA + ADG+ARA+G Sbjct 25 LMDSLHRHGVTHIFGYPGGAILPIYDELYHWEDAGKIQHILVRHEQGASHAADGYARATG 84 Query 64 KSAAVF-VAGPGATNVISAVANASVNQVPMLILTGEVAVGEFGLHSQQDTSDDGLGLGAT 122 K F +GPGATN+++ +A A ++ +P++ +TG+VA G + Q+T G+ L Sbjct 85 KVGVCFATSGPGATNLVTGIATAHMDSIPLICVTGQVARPAIGSDAFQETDIFGITLPVV 144 Query 123 FRRFCRCSVSIESIANARSKIDSAFRALASIPRGPVHIALPRDLVDERLPAHQLGTAAAG 182 + S + A+ + AF ++ GPV I +P+D+ E + Sbjct 145 -----KHSYVVRDPADMARIVAEAFHIASTGRPGPVLIDVPKDVGLEECDYVPVEANQLK 199 Query 183 LGGLRTLAPCGPDVADEVIGRLDRSRAPMLVLGNGCRLDGIGEQIVAFCEKAGLPFATTP 242 L G R P ++ + + ++R P+L +G G G +++ E +P TT Sbjct 200 LVGYRPTVKGNPRQINQALNLIRQARRPLLYVGGGTIAAGAHDELRQLAEIFQIPVTTTL 259 Query 243 NGRGIVAETHPLSLGVLGIFGDGRADEYLFDTPCDLLIAVGVSFGGLVTRSFSPRWRGLK 302 G+G E+HPLS+ +LG+ G A+ + + CDLLIAVG F VT Sbjct 260 MGKGAFDESHPLSVKMLGMHGTAYANFAV--SECDLLIAVGTRFDDRVTGKLDQF--ACH 315 Query 303 ADVVHVDPDPSAVGRFVATSLGITTSGRAFVN-------ALNCGRPP----RFCRRVG-V 350 A V+H+D DP+ VG+ + + I R + +N P + R+ Sbjct 316 AQVIHIDIDPAEVGKNRSPQVPIVGDVRRVLQYMLRRYQEMNISAEPNQTQEWLARINRW 375 Query 351 RPPAPAALPGTPQARGESIHPLELMHELDRELAPNATICADVGTCISWTFRGIPVRRPGR 410 R P +P P +S+ P E++ E+ R+ AP A DVG W + + P + Sbjct 376 REDYPLQVPQYP----DSLSPQEVIVEVGRQ-APKAYYTTDVGQHQMWAAQFLN-NGPRQ 429 Query 411 FFATVDFSPMGCGIAGAIGVALARPEEHVICIAGDGAFLMHGTEISTAVAHGIRVTWAVL 470 + ++ MG G+ A+GV +A P++ VICIAGD + M+ E+ T +GI V ++ Sbjct 430 WISSGGLGTMGYGMPAAMGVQVALPDQQVICIAGDASIQMNIQELGTLAQYGINVKTVII 489 Query 471 ND---GQMSASAGPVSGRMDPSPVARIGANDLAAMARALGAEGIRVDTRCELRAGVQKAL 527 N+ G + G+ S +G D +A+A G +G+ V +R +L+ + + L Sbjct 490 NNGWQGMVRQWQQAFFGQRYSSSNMEVGMPDFVQLAQAYGVKGMIVTSRDQLQDAIAQML 549 Query 528 AATGPCVLDIAIDPEIN 544 A GP +LD+ + + N Sbjct 550 AYDGPVLLDVHVTKDEN 566 >gi|83645355|ref|YP_433790.1| thiamine pyrophosphate-requiring enzyme [Hahella chejuensis KCTC 2396] gi|83633398|gb|ABC29365.1| thiamine pyrophosphate-requiring enzyme [Hahella chejuensis KCTC 2396] Length=584 Score = 207 bits (527), Expect = 4e-51, Method: Compositional matrix adjust. Identities = 169/565 (30%), Positives = 255/565 (46%), Gaps = 32/565 (5%) Query 4 GDHLVARMRAAGISVVCGLPTSRLDSL---LVRLSRDAGFQIVLARHEGGAGYLADGFAR 60 GD ++ + G+ V G+P ++ L L R R G + VLARHE GA ++ADG+AR Sbjct 5 GDLILHYLERLGVKYVFGVPGGSIEPLYNALARSERRGGPKAVLARHESGAAFMADGYAR 64 Query 61 ASGK-SAAVFVAGPGATNVISAVANASVNQVPMLILTGEVAVGEFGLHSQQDTSDDGLGL 119 A+GK + +GPGATN+++ VANA + +PML++T + ++ FGL + Q+ S G+ Sbjct 65 ATGKLGVCISTSGPGATNLLTGVANAYADGIPMLVITAQPSIERFGLGAFQEGSCTGINT 124 Query 120 GATFRRFCRCSVSIESIANARSKIDSAFRALASIPRGPVHIALPRDLVDERLPAHQLGTA 179 + F R + + A K+ A S GPVH+++P D++ + P Sbjct 125 VSIFDSCTRFNTLVSHPAQLEHKLLMAIGYALSNQPGPVHLSVPLDIMRAKSP------D 178 Query 180 AAGLGGLRTLAPCGPDVADEVIGRLDRSRAPM----LVLGNGCRLDGIGEQIVAFCEKAG 235 AG +R + E + RL + A + LV+G GC G E ++A E Sbjct 179 PAGNLNMRAFINHEVVPSAESVHRLLKELAYVQKATLVIGEGCA--GAMEPLLALAESRN 236 Query 236 LPFATTPNGRGIVAETHPLSLGVLGIFGDGRADEYLFDTPCDLLIAVGVSFGGLVTRSFS 295 TTP G+G+V+E HPL GV G+ G A + L + +I +G + + T + Sbjct 237 WLIVTTPMGKGLVSEYHPLYRGVFGLGGHESARDALHPDNAERVIVIGSALDEVTTGGWD 296 Query 296 PRWRGLKADVVHVDPDPSAVGRFVATSLGITTSGRAFVNALNCGRPPRFCRRVGVRPPAP 355 P ++H+ +P + R V + L I S R + R+ P A Sbjct 297 PN-AIFSNRLIHLSGNPDHLSRSVMSRLSILGSPRLLLEPFAKYLKHAAPRKQKYLPGAD 355 Query 356 AALPGTPQARGES-------IHPLELMHELDRELAPNATICADVGTCISWTFRGIPVRRP 408 A E+ + P L L + N + D G W P Sbjct 356 GFPKHVKYADKEACLDVEAPVKPQALYWALSQACPRNTPVLMDTGNSFLWGVHYWRTNPP 415 Query 409 -----GRFFATVDFSPMGCGIAGAIGVALARPEEHVICIAGDGAFLMHGTEISTAVAHGI 463 F + F+ MG I A+G+ALARP+ VIC GDG+ LM G EI+ A + Sbjct 416 LSDSTKLFHIGMGFATMGWAIGAAVGMALARPDTPVICFTGDGSMLMSGQEITVARELDL 475 Query 464 RVTWAVLNDGQMSA-SAGPVSGRMDPSPVARIGANDLAAMARALGAEGIRVDTRCEL-RA 521 + + VLND + G GR + R+ D AAMA+A G R+ EL Sbjct 476 NILFIVLNDSHLGMIKHGQRLGRAE-DIANRLPQVDFAAMAKAAGLPSQRITRLKELDDI 534 Query 522 GVQKALAATGPCVLDIAIDPEINKP 546 GV + GP VLD+ +D E P Sbjct 535 GVDSLFSKPGPFVLDVVVDSEQVPP 559 >gi|148262699|ref|YP_001229405.1| acetolactate synthase, large subunit type [Geobacter uraniireducens Rf4] gi|146396199|gb|ABQ24832.1| acetolactate synthase, large subunit, biosynthetic type [Geobacter uraniireducens Rf4] Length=560 Score = 207 bits (526), Expect = 5e-51, Method: Compositional matrix adjust. Identities = 162/549 (30%), Positives = 258/549 (47%), Gaps = 34/549 (6%) Query 7 LVARMRAAGISVVCGLPTSRLDSLLVR--LSRDAGFQIVLARHEGGAGYLADGFARASGK 64 L+ ++ G+ + G P ++ +LLV L D + +L RHE GA + ADG+AR +GK Sbjct 8 LLECLKREGVDTIFGYPGAK--TLLVHDALYDDPDLRHILVRHEQGAAHAADGYARTTGK 65 Query 65 SAAVFV-AGPGATNVISAVANASVNQVPMLILTGEVAVGEFGLHSQQDTSDDGLGLGATF 123 +GPGATN+++ +A A ++ +P++ LT +VA + G + Q+ D +G+ Sbjct 66 VGVCLTTSGPGATNLVTGIATAHMDSIPLVALTCQVATTDIGSDAFQEA--DMIGITRPI 123 Query 124 RRFCRCSVSIESIANARSKIDSAFRALASIPRGPVHIALPRD-LVDERLPAHQLGTAAAG 182 + ++ +A + AF ++ GP+ I LP + L + +P A G Sbjct 124 TKHNYLVTDVKELAGI---VHEAFSVARTLRPGPILIDLPSNVLAAKTVPVIPETVARRG 180 Query 183 LGGLRTLAPCGPDVADEVIGRLDRSRAPMLVLGNGCRLDGIGEQIVAFCEKAGLPFATTP 242 ++ A E+I R R P++ G G L G ++ A K G+P T Sbjct 181 YRSRVSVNDKQLKKAAEIINRAKR---PLIYAGGGITLAGASAELRALAAKGGIPVTHTL 237 Query 243 NGRGIVAETHPLSLGVLGIFGDGRADEYLFDTPCDLLIAVGVSFGGLVT---RSFSPRWR 299 G++ PLS+G+LG++G A+ + D CD L+A+G F VT F+PR Sbjct 238 MAIGVMDPASPLSIGMLGMYGAWHANRAVHD--CDCLVAIGARFDDRVTGRLDGFAPR-- 293 Query 300 GLKADVVHVDPDPSAVGRFVATSLGITTSGRAFVNALNCGRPPRFCRRVGVRPPAPAALP 359 AD++H+D DPS++ + +L I + + L R R A Sbjct 294 ---ADIIHIDIDPSSIRKVTNRALPIVGDAKEAMALLAGLLEVRDRSAWQARIAAWEQEA 350 Query 360 GTPQARGESIHPLELMHELDRELAPNATICADVGTCISWTFRGIPVRRPGRFFATVDFSP 419 P+ + E + P E+M L P + +DVG WT + P RF + Sbjct 351 PLPRPKREHLVPHEIMAALGEACGPTPIVASDVGLSQMWTANYLGFSAPRRFITSGGLGT 410 Query 420 MGCGIAGAIGVALARPEEHVICIAGDGAFLMHGTEISTAVAHGIRVTWAVLNDGQMSASA 479 MG + A+G L P E VI I GDGAF M+ E++T + I V VLN+G++ Sbjct 411 MGYALPAAMGAVLGNPGETVIAITGDGAFQMNIQELATCAYYNIPVKTIVLNNGKL---- 466 Query 480 GPVSGRMDPSPVARIGANDLAA------MARALGAEGIRVDTRCELRAGVQKALAATGPC 533 G V + R A DL +AR G E +RV + EL +++A+A GP Sbjct 467 GMVRQFQNIFLKQRYAATDLGKHVDFCMVARGFGVEALRVSRKEELAPALRRAMAIAGPV 526 Query 534 VLDIAIDPE 542 V+D+ IDP+ Sbjct 527 VVDVEIDPD 535 >gi|283853803|ref|ZP_06371026.1| thiamine pyrophosphate protein domain protein TPP-binding [Desulfovibrio sp. FW1012B] gi|283570807|gb|EFC18844.1| thiamine pyrophosphate protein domain protein TPP-binding [Desulfovibrio sp. FW1012B] Length=576 Score = 206 bits (523), Expect = 1e-50, Method: Compositional matrix adjust. Identities = 168/571 (30%), Positives = 249/571 (44%), Gaps = 45/571 (7%) Query 6 HLVARMRAAGISVVCGLPTSRLDSLLVRLSRDAGFQIVLARHEGGAGYLADGFARASGKS 65 +L++ + A G+ V +P +D L L+ G ++A HE GA +ADG+ARASG+ Sbjct 6 YLLSSLVAEGVDHVFLVPGGLVDPFLPDLAATPGLTPIVAAHESGAAAMADGYARASGRF 65 Query 66 AAVF-VAGPGATNVISAVANASVNQVPMLILTGEVAVGEFGLHSQQDTSDDGLGLGATFR 124 A + GPGATN+ + A+A + P+L LTG+V G QD+S A Sbjct 66 GACLAIGGPGATNLATVAASARADASPVLFLTGQVPTDWEGRGGFQDSSAATFDDTALLS 125 Query 125 RFCRCSVSIESIANARSKIDSAFRALASIPRGPVHIALPRDL-----------VDERLPA 173 S+S+E+ + + + + P+ PVH++LP D+ +DE + Sbjct 126 HVTAASLSVENPHLVHHHLRACLTRMLAGPKAPVHMSLPLDIQRADVAAPWEPLDESVYR 185 Query 174 HQLGTAAAGLGGLRTLAPCGPDVADEVIGRLDRSRAPMLVLGNGCRLDGIGEQIVAFCEK 233 + AA R L P G A + ++ G G G E + AF E+ Sbjct 186 PRFADRAAVERLWRILVPEGGGAAPVRVA---------ILAGAGVEKSGATESLTAFAEQ 236 Query 234 AGLPFATTPNGRGIVAETHPLSLGVLGIFGDGRADEYLFDTPCDLLIAVGVSFGGLVTRS 293 +P ATT +G+ E H LSLGV G G A E L ++LI +G T Sbjct 237 FEIPVATTLRAKGVFPEDHRLSLGVFGYAGHRPAIEALLSGQVEVLIVLGSGLSQRDTLF 296 Query 294 FSPRWRGLKADVVHVDPDPSAVGRFVATSLGIT-----------TSGRAFVNALNCGRPP 342 + + +A +V VD DP+ VGR T + + G A + G Sbjct 297 WDAKMLPSRA-LVQVDVDPTVVGRTFHTHVPVVGDCRAALALMMEPGSARIMRFRSGNES 355 Query 343 RFCRRVGVRPPAPAAL-PGTPQARGESIHPLELMHELDRELAPNATICADVGTCISWTFR 401 R G+R P + +HP + EL R L A + D G ++ Sbjct 356 RAAWLGGIRQSGRTCYDPEQMTSEAVPLHPARVAAELRRALPREAAVVVDSGAHRAFFAH 415 Query 402 GIPVRRPGRFFATVDFSPMGCGIAGAIGVALARPEEHVICIAGDGAFLMHGTEISTAVAH 461 P +F + PMG I AIGV ARP V C+ GDG LMHG E++TA + Sbjct 416 YFQAFGPRTYFTAANLGPMGWAIGAAIGVQAARPGRPVACVTGDGCMLMHGMEVATAARY 475 Query 462 GIRVTWAVLNDGQM------SASAGPVSGRMDPSPVARIGANDLAAMARALGAEGIRVDT 515 G + + V+N+G + + GP +G + A + D AA RA+GA G+ V Sbjct 476 GFPILYVVINNGALGNVWLRAVEDGPGAGAL-----AELPGRDFAAFGRAMGARGLAVTR 530 Query 516 RCELRAGVQKALAATGPCVLDIAIDPEINKP 546 EL + LA GPCV+D+ D P Sbjct 531 PEELAPAFAEGLAGNGPCVIDVRCDRTARTP 561 >gi|254433415|ref|ZP_05046923.1| Thiamine pyrophosphate enzyme, central domain family [Nitrosococcus oceani AFC27] gi|207089748|gb|EDZ67019.1| Thiamine pyrophosphate enzyme, central domain family [Nitrosococcus oceani AFC27] Length=589 Score = 206 bits (523), Expect = 1e-50, Method: Compositional matrix adjust. Identities = 172/584 (30%), Positives = 271/584 (47%), Gaps = 64/584 (10%) Query 4 GDHLVARMRAAGISVVCGLPTSRLDSL---LVRLSRDAGFQIVLARHEGGAGYLADGFAR 60 GD LVA + + V G+P ++ L L R +R G + V+ARHE GA ++ADG+ R Sbjct 9 GDLLVAYLAQLSVDYVFGVPGGAIEPLYNALARSARKGGPRAVVARHETGAAFMADGYGR 68 Query 61 ASGKSAAV-FVAGPGATNVISAVANASVNQVPMLILTGEVAVGEFGLHSQQDTSDDGLGL 119 +GK A GPGATN+I+ VA+A N++PML++T + A+ FG + Q++S G+ Sbjct 69 QTGKLAVCCATTGPGATNLITGVASAYENRIPMLVITAQTALSHFGRGALQESSCTGIDT 128 Query 120 GATFRRFCRCSVSIESIANARSKIDSAFRALASIPRGPVHIALPRDLVDE----RLPAHQ 175 F+ R S + +A K+ +A P GP H+++P D++ ++P++Q Sbjct 129 VNLFQHCTRYSTLVSHVAQLEHKLSTAIMTAYQSPNGPTHLSIPLDILRSAAPVKIPSYQ 188 Query 176 LGTAAAGLGGLRTLAPCGPDVADEVIGRLDRSRAPMLVLGNGCR--LDGIGEQIVAFCEK 233 L L A ++ + + ++ ++ + V+G CR +D I + +AF + Sbjct 189 LAAL------LHHPALLDENMIEALCDQIASAKKVVFVVGEDCREAIDAILD--LAFLIQ 240 Query 234 AGLPFATTPNGRGIVAETHPLSLGVLGIFGDGRADEYLFDTPCDLLIAVGVSFGGLVTRS 293 + + TTP+G+G+V+ HPL GV+G G A E L D D ++ G + G + Sbjct 241 SDV--VTTPHGKGLVSPYHPLFRGVIGFAGHRSASEILSDPEVDTVVVFGANLGEWASNG 298 Query 294 FSPRWRGLKADVVHVDPDPSAVGRFVATSLGI----TTSGRAFVNALNCGRPPRFCRRVG 349 + L ++HV+ + R L + TT ++ L P R G Sbjct 299 WDTE-ALLNDRLIHVENTQENLTRTPMARLHVRGTLTTICERVLSYLRQRLPTEEERAPG 357 Query 350 V---RPPAP--AALPGTPQARGE------------SIHPLELMHELDRELAPNATICADV 392 V +P +P AL P+ R + I P LM EL R N AD Sbjct 358 VERRQPDSPLREALRQEPKRRFQFDEEAKYHDNSTPIKPQRLMKELTRLFPSNTRFLADS 417 Query 393 GTCISWTFRGI-PVRRPGR----FFATVDFSPMGCGIAGAIGVALARPEEHVICIAGDGA 447 G I+W + P + R F +DF+ MG I A+G AL P V+CI GDG+ Sbjct 418 GNSIAWAIHYLQPSWQSDRNGEPFRGCLDFAAMGWAIGAAVGSALGAPGNPVVCITGDGS 477 Query 448 FLMHGTEISTAVAHGIRVTWAVLND--------GQMSASAGPVSGRMDPSPVARIGANDL 499 +LM G EI+ A + V + +LND GQ A A V + A + Sbjct 478 WLMSGQEITVASQEQLPVIFIILNDAALGMVKHGQRLAQAEAVGFELP--------AINY 529 Query 500 AAMARALGAEGIRVDTRCELRAGVQKALAA-TGPCVLDIAIDPE 542 A A+G + + +L KA+ GP +LD+ +DPE Sbjct 530 CAYGEAMGVPSHIIRSPQDLMVLDIKAICKRQGPTLLDVRVDPE 573 >gi|77164772|ref|YP_343297.1| acetolactate synthase large subunit [Nitrosococcus oceani ATCC 19707] gi|76883086|gb|ABA57767.1| Acetolactate synthase large subunit [Nitrosococcus oceani ATCC 19707] Length=602 Score = 205 bits (522), Expect = 1e-50, Method: Compositional matrix adjust. Identities = 172/584 (30%), Positives = 271/584 (47%), Gaps = 64/584 (10%) Query 4 GDHLVARMRAAGISVVCGLPTSRLDSL---LVRLSRDAGFQIVLARHEGGAGYLADGFAR 60 GD LVA + + V G+P ++ L L R +R G + V+ARHE GA ++ADG+ R Sbjct 22 GDLLVAYLAQLSVDYVFGVPGGAIEPLYNALARSARKGGPRAVVARHETGAAFMADGYGR 81 Query 61 ASGKSAAV-FVAGPGATNVISAVANASVNQVPMLILTGEVAVGEFGLHSQQDTSDDGLGL 119 +GK A GPGATN+I+ VA+A N++PML++T + A+ FG + Q++S G+ Sbjct 82 QTGKLAVCCATTGPGATNLITGVASAYENRIPMLVITAQTALSHFGRGALQESSCTGIDT 141 Query 120 GATFRRFCRCSVSIESIANARSKIDSAFRALASIPRGPVHIALPRDLVDE----RLPAHQ 175 F+ R S + +A K+ +A P GP H+++P D++ ++P++Q Sbjct 142 VNLFQHCTRYSTLVSHVAQLEHKLSTAIMTAYQSPNGPTHLSIPLDILRSAAPVKIPSYQ 201 Query 176 LGTAAAGLGGLRTLAPCGPDVADEVIGRLDRSRAPMLVLGNGCR--LDGIGEQIVAFCEK 233 L L A ++ + + ++ ++ + V+G CR +D I + +AF + Sbjct 202 LAAL------LHHPALLDENMIEALCDQIASAKKVVFVVGEDCREAIDAILD--LAFLIQ 253 Query 234 AGLPFATTPNGRGIVAETHPLSLGVLGIFGDGRADEYLFDTPCDLLIAVGVSFGGLVTRS 293 + + TTP+G+G+V+ HPL GV+G G A E L D D ++ G + G + Sbjct 254 SDV--VTTPHGKGLVSPYHPLFRGVIGFAGHRSASEILSDPEVDTVVVFGANLGEWASNG 311 Query 294 FSPRWRGLKADVVHVDPDPSAVGRFVATSLGI----TTSGRAFVNALNCGRPPRFCRRVG 349 + L ++HV+ + R L + TT ++ L P R G Sbjct 312 WDTE-ALLNDRLIHVENTQENLTRTPMARLHVRGTLTTICERVLSYLRQRLPTEEERAPG 370 Query 350 V---RPPAP--AALPGTPQARGE------------SIHPLELMHELDRELAPNATICADV 392 V +P +P AL P+ R + I P LM EL R N AD Sbjct 371 VERRQPDSPLREALRQEPKRRFQFDEEAKYHDNSTPIKPQRLMKELTRLFPSNTRFLADS 430 Query 393 GTCISWTFRGI-PVRRPGR----FFATVDFSPMGCGIAGAIGVALARPEEHVICIAGDGA 447 G I+W + P + R F +DF+ MG I A+G AL P V+CI GDG+ Sbjct 431 GNSIAWAIHYLQPSWQSDRNGEPFRGCLDFAAMGWAIGAAVGSALGAPGNPVVCITGDGS 490 Query 448 FLMHGTEISTAVAHGIRVTWAVLND--------GQMSASAGPVSGRMDPSPVARIGANDL 499 +LM G EI+ A + V + +LND GQ A A V + A + Sbjct 491 WLMSGQEITVASQEQLPVIFIILNDAALGMVKHGQRLAQAEAVGFELP--------AINY 542 Query 500 AAMARALGAEGIRVDTRCELRAGVQKALAA-TGPCVLDIAIDPE 542 A A+G + + +L KA+ GP +LD+ +DPE Sbjct 543 CAYGEAMGVPSHIIRSPQDLMVLDIKAICKRQGPTLLDVRVDPE 586 >gi|56478123|ref|YP_159712.1| acetolactate synthase catalytic subunit [Aromatoleum aromaticum EbN1] gi|56314166|emb|CAI08811.1| putative acetolactate synthase large subunit [Aromatoleum aromaticum EbN1] Length=555 Score = 205 bits (522), Expect = 2e-50, Method: Compositional matrix adjust. Identities = 175/556 (32%), Positives = 263/556 (48%), Gaps = 42/556 (7%) Query 4 GDHLVARM-RAAGISVVCGLPTSRLDSLLVRLSRDAGFQIVLARHEGGAGYLADGFARAS 62 G L+ R+ GI V G+P + L LS + VLARHE GAG++A G AR S Sbjct 6 GAELILRLLERQGIRTVAGIPGGAILPLYDALSGSKLIRHVLARHEQGAGFIAQGMARVS 65 Query 63 GKSAAVFVA-GPGATNVISAVANASVNQVPMLILTGEVAVGEFGLHSQQDTSDDGLGLGA 121 G+ F + GPGATN+++A+A+A ++ +PM+ +TG+V + G + Q+ G+ + Sbjct 66 GRPEVCFASSGPGATNLVTAIADAHLDSIPMVAITGQVPLSMIGTDAFQEADIYGMTVPV 125 Query 122 TFRRFCRCSVSIESIANARSKIDSAFRALASIPRGPVHIALPRDLVDERLPAHQLGTAAA 181 T F + S A I AFR S GPV I +P+D+ + + A Sbjct 126 TKHNFL-----VRSAAELLEVIPDAFRLAMSGRPGPVLIDIPKDVQTQ-----VVSFDAF 175 Query 182 GLGGLRTLAPCG-PDVADEVIGRLDRSRAPMLVLGNGCRLDGIGEQIVAFCEKAGLPFAT 240 L + AP PD +E ++ + P+L +G G G +QIV E+AGLP Sbjct 176 PLPAIPNAAPASDPDAIEEAARLINAAERPVLYVGGGVIHSGAAQQIVMLAERAGLPTTM 235 Query 241 TPNGRGIVAETHPLSLGVLGIFGDGRADEYLFDTPCDLLIAVGVSFGGLVT---RSFSPR 297 T G++ HPLSLG+LG+ G R ++ + DLLI VG F F PR Sbjct 236 TLMALGVMPIDHPLSLGMLGMHG-ARYTNFILEE-SDLLICVGARFDDRAIGKAAQFCPR 293 Query 298 WRGLKADVVHVDPDPSAVGRFVATSLGITTSGRAFVNAL----NCGRPPRFCRRVG-VRP 352 A +VH+D DPS + + + I ++AL N R+ VG ++ Sbjct 294 -----AKIVHIDIDPSELHKIRNAHVAINGDVGVVLDALLPRVNIRLRKRWLSHVGSLKS 348 Query 353 PAPAALPGTPQARGESIHPLELMHELDRELAPNATICADVGTCISWTFRGIPVRRPGRFF 412 P +P R P L+ + ++ A + DVG W + P RRP ++ Sbjct 349 RFPLHMPRLEDPRS----PYGLVQAVACAVSDEAVVTTDVGQHQMWVAQAYPFRRPRQWL 404 Query 413 ATVDFSPMGCGIAGAIGVALARPEEHVICIAGDGAFLMHGTEISTAVAHGIRVTWAVLND 472 + F MG G+ A+G ALA P VIC GDG+F M+ E++T G+ V ++N+ Sbjct 405 TSGGFGTMGFGLPVAVGAALAAPARTVICFTGDGSFKMNIQELATLAEEGLNVKIVLMNN 464 Query 473 GQMSASAGPVSGRMDPSPVARI------GANDLAAMARALGAEGIRVDTRCELRAGVQKA 526 S G V + R+ GA D +A G +G+ +DT RA + +A Sbjct 465 N----SLGLVYQQQSLFYGKRVFASKYQGAPDFLKIAEGFGIDGVDLDTVRNPRAALAQA 520 Query 527 LAATGPCVLDIAIDPE 542 L A GPC++ +ID E Sbjct 521 LNAPGPCLIHASIDCE 536 >gi|332704423|ref|ZP_08424511.1| acetolactate synthase, large subunit, biosynthetic type [Desulfovibrio africanus str. Walvis Bay] gi|332554572|gb|EGJ51616.1| acetolactate synthase, large subunit, biosynthetic type [Desulfovibrio africanus str. Walvis Bay] Length=571 Score = 205 bits (521), Expect = 2e-50, Method: Compositional matrix adjust. Identities = 172/556 (31%), Positives = 269/556 (49%), Gaps = 42/556 (7%) Query 1 VTVGDHLVARMRAAGISVVCGLPTSRLDSLLVRLSRDAGFQIVLARHEGGAGYLADGFAR 60 +T + +V + G++VV G+P L LSR + VLARHE GAG++A G AR Sbjct 7 MTGAEIIVRLLERQGVAVVAGIPGGANLPLYDALSRSP-IRHVLARHEQGAGFIAQGMAR 65 Query 61 ASGKSAAVF-VAGPGATNVISAVANASVNQVPMLILTGEVAVGEFGLHSQQDTSDDGLGL 119 +G+ A +GPGATN+++A+A+A ++ VP++ +TG+V G G + Q+ GL + Sbjct 66 TTGRPAVCLATSGPGATNLLTAIADAKLDSVPLVCITGQVPRGLLGTDAFQEVDTYGLAM 125 Query 120 GATFRRFCRCSVSIESIANARSKIDSAFRALASIPRGPVHIALPRDLVDERLPAHQLGTA 179 T + S S + I AFR +S GPV + +P+D+ E Q Sbjct 126 PITKHAWLARSAS-----ELLTIIPEAFRLASSGRAGPVLVDVPKDVQQEYAEFDQWPEP 180 Query 180 AAGLGGLRTLAPCGPDVADEVIGR----LDRSRAPMLVLGNGCRLDGIGEQIVAFCEKAG 235 GL L GPD+ +V+ R LD +R P ++LG G G E V E+ Sbjct 181 -----GLPELV-AGPDI--QVLERAAALLDSARRPAMILGGGVIASGASELAVRLAERCA 232 Query 236 LPFATTPNGRGIVAETHPLSLGVLGIFGDGRADEYLFDTPCDLLIAVGVSFG----GLVT 291 +P A T G G + HP LG+LG+ G + L + CDLL+AVG+ F G+ + Sbjct 233 MPTAMTLMGLGAMPAGHPQYLGMLGMHGMRCTNTILHE--CDLLLAVGMRFDDRATGVAS 290 Query 292 RSFSPRWRGLKADVVHVDPDPSAVGRFVATSLGITTSGRAFVNAL--NCGRPPR--FCRR 347 R F P +A+++H+D D S +G+ + S+G+ T + AL + PR + R Sbjct 291 R-FCP-----EAEIIHIDIDASEIGKIKSASVGLATDAAQALEALLGMTRQRPRVGWQHR 344 Query 348 VGVRPPAPAALPGTPQARGESIHPLELMHELDRELAPNATICADVGTCISWTFRGIPVRR 407 V A AAL + + P ++ L +L +A I DVG WT P RR Sbjct 345 VRQIRQADAALD---ELNTDLRTPRGILASLAAQLPEDAIIVTDVGQHQMWTAMHYPFRR 401 Query 408 PGRFFATVDFSPMGCGIAGAIGVALARPEEHVICIAGDGAFLMHGTEISTAVAHGIRVTW 467 P + MG G+ AIG ALA+P+ ++ + GDG+ M+ E++TA G +T Sbjct 402 PRTLLTSGGLGTMGFGLPTAIGAALAKPDARIVLVTGDGSLQMNLQELATAAEEGANITI 461 Query 468 AVLNDGQM---SASAGPVSGRMDPSPVARIGANDLAAMARALGAEGIRVDTRCELRAGVQ 524 ++++G + GR + R G D +AR G + + A + Sbjct 462 VLMDNGSLGLVHQQQDLFFGRRHYASTFRHGV-DFCQVARGFGMRAANLHEARDPHAAMS 520 Query 525 KALAATGPCVLDIAID 540 +AL +GPC++ +D Sbjct 521 RALCGSGPCLIRARVD 536 >gi|81298950|ref|YP_399158.1| acetolactate synthase 3 catalytic subunit [Synechococcus elongatus PCC 7942] gi|81167831|gb|ABB56171.1| acetolactate synthase, large subunit [Synechococcus elongatus PCC 7942] gi|226945|prf||1611501A acetolactate synthase Length=612 Score = 205 bits (521), Expect = 2e-50, Method: Compositional matrix adjust. Identities = 163/558 (30%), Positives = 255/558 (46%), Gaps = 36/558 (6%) Query 7 LVARMRAAGISVVCGLPTSRLDSLLVRLSRDAG---FQIVLARHEGGAGYLADGFARASG 63 L+ + G+ + G P + + L R Q +L RHE GA + AD ++RA+G Sbjct 18 LIDSLCQHGVKHIFGYPGGAILPIYDELHRAEAAGRVQHILVRHEQGAVHAADAYSRATG 77 Query 64 KSAAVF-VAGPGATNVISAVANASVNQVPMLILTGEVAVGEFGLHSQQDTSDDGLGLGAT 122 + F +GPGATN+++ +A A ++ +PM+++TG+V G + Q+T G+ L Sbjct 78 EVGVCFATSGPGATNLVTGIATAQMDSIPMVVVTGQVPRTAIGTDAFQETDIYGITLP-- 135 Query 123 FRRFCRCSVSIESIANARSKIDSAFRALASIPRGPVHIALPRDLVDERLPAHQLGTAAAG 182 + S + + + AF S GPV I +P+D+ E + Sbjct 136 ---IVKHSYVVRDPRDMARIVAEAFHIAQSGRPGPVLIDVPKDVGTEEFDYVPVAPGDIR 192 Query 183 LGGLRTLAPCGPDVADEVIGRLDRSRAPMLVLGNGCRLDGIGEQIVAFCEKAGLPFATTP 242 L G R P + I + +R P+L +G G G ++ AF E+ LP TT Sbjct 193 LPGYRPTTRGNPRQIAQAIALVKVARRPLLYVGGGAITAGAHAELRAFAERFQLPVTTTL 252 Query 243 NGRGIVAETHPLSLGVLGIFGDGRADEYLFDTPCDLLIAVGVSFGGLVTRSFSPRWRGLK 302 G+G E HPL+LG+LG+ G A+ + + CDLLIAVG F VT K Sbjct 253 MGKGAFDERHPLALGMLGMHGTAYANFAV--SECDLLIAVGARFDDRVTGKLDE--FASK 308 Query 303 ADVVHVDPDPSAVGRFVATSLGITTSGRAFVNAL-----------NCGRPPRFCRRVGV- 350 A V+HVD DP+ VG+ + I R +N L + R + R+ Sbjct 309 AQVIHVDIDPAEVGKNRVPEVPIVGDVRQVLNELLARAEEQISADDATRTQPWLDRIAYW 368 Query 351 RPPAPAALPGTPQARGESIHPLELMHELDRELAPNATICADVGTCISWTFRGIPVRRPGR 410 + P +P + + P +++H L E AP+A DVG W + I P R Sbjct 369 KREYPLQIP----YYADVLSPQQVIHSLG-EAAPDAYFTTDVGQHQMWAAQFIK-NGPRR 422 Query 411 FFATVDFSPMGCGIAGAIGVALARPEEHVICIAGDGAFLMHGTEISTAVAHGIRVTWAVL 470 + ++ MG G+ A+G +A P++ VIC+AGD + LM+ E+ T + I + V+ Sbjct 423 WISSAGLGTMGFGMPAAMGAQMALPDDTVICVAGDASILMNIQELGTLAQYNIPIKVVVV 482 Query 471 NDGQM----SASAGPVSGRMDPSPVARIGANDLAAMARALGAEGIRVDTRCELRAGVQKA 526 N+G R S + R G D +A A G +G+RV EL+A + + Sbjct 483 NNGWQGMVRQWQEAFYDERYSNSNMER-GMPDFVKLAEAFGIKGMRVSHPDELQAAIAEM 541 Query 527 LAATGPCVLDIAIDPEIN 544 LA GP LD + + N Sbjct 542 LAFDGPVFLDAIVKRDEN 559 >gi|91202797|emb|CAJ72436.1| strongly similar to acetohydroxy acid synthase IilvB [Candidatus Kuenenia stuttgartiensis] Length=565 Score = 204 bits (520), Expect = 2e-50, Method: Compositional matrix adjust. Identities = 162/562 (29%), Positives = 259/562 (47%), Gaps = 43/562 (7%) Query 1 VTVGDH-LVARMRAAGISVVCGLPTSRLDSLLVRLSRDAGFQIVLARHEGGAGYLADGFA 59 + G H L+ + G+ V G+P + L L ++ + +L RHE GAG+ ADGFA Sbjct 10 IKTGSHILINALIREGVEYVFGIPGGAVLPLFDAL-YESQIKFILTRHEQGAGHAADGFA 68 Query 60 RASGKSAAVF-VAGPGATNVISAVANASVNQVPMLILTGEVAVGEFGLHSQQDTSDDGLG 118 RA+GK +GPGATN+ +A+A A ++ VPM+ LTG+V G + Q+ G+ Sbjct 69 RATGKVGVCLATSGPGATNLTTAIATAYMDSVPMVALTGQVKTFLIGNDAFQEVDIIGIT 128 Query 119 LGATFRRFCRCSVSIESIANARSKIDSAFRALASIPRGPVHIALPRDLV----DERLPAH 174 R + S ++ + + + AF S +GPV I LP D+ +E +P Sbjct 129 -----RPITKHSYLVKDVKDLARVVKEAFYLANSGRQGPVLIDLPVDVTMAECEEIIPPE 183 Query 175 --QLGTAAAGLGGLRTLAPCGPDVADEVIGRLDRSRAPMLVLGNGCRLDGIGEQIVAFCE 232 G G +R + +A EVI + +R P+L G G ++++ E Sbjct 184 IDLPGYKPTYEGNIRQIK-----IAAEVI---NNARRPVLYTGGGIIASDSAKELLELAE 235 Query 233 KAGLPFATTPNGRGIVAETHPLSLGVLGIFGDGRADEYLFDTPCDLLIAVGVSFGGLVT- 291 K +P TT G G E H LSLG+LG+ G A+ + T CD+LIA+G F +T Sbjct 236 KGNIPVTTTLMGLGGFPENHNLSLGMLGMHGTAYANFAV--TTCDILIAIGARFDDRITG 293 Query 292 --RSFSPRWRGLKADVVHVDPDPSAVGRFVATSLGITTSGRAFVNALN-----CGRPPRF 344 F+P A ++H+D DPS++ + + + + + + LN R F Sbjct 294 KIDEFAPN-----AKIIHIDIDPSSISKNIKVDIPVVGYAQNTLRELNKHISFVERREWF 348 Query 345 CRRVGVRPPAPAALPGTPQARGESIHPLELMHELDRELAPNATICADVGTCISWTFRGIP 404 + + P T G+ I P ++ ++ A I +VG W + Sbjct 349 DKIKQWKEQNPL----TYNNSGDLIKPQYVIEQIYEATNGEAIITTEVGQNQMWAAQYYT 404 Query 405 VRRPGRFFATVDFSPMGCGIAGAIGVALARPEEHVICIAGDGAFLMHGTEISTAVAHGIR 464 +P F ++ MG G AIG L P++ V+ IAGDG+ M+ E+ST V I Sbjct 405 YTKPRTFLSSGGLGTMGYGFPAAIGAQLGCPDKIVVDIAGDGSIQMNIQELSTVVRLNIP 464 Query 465 VTWAVLNDGQMSASAGPVSGRMDP--SPVARIGANDLAAMARALGAEGIRVDTRCELRAG 522 V +LN+G + D S V+ G D +A + GA+G ++ + ++R Sbjct 465 VKIVILNNGYLGMVRQWQELFYDKRYSSVSLNGNPDFVKLAESYGAKGFLIEKKEDVRPT 524 Query 523 VQKALAATGPCVLDIAIDPEIN 544 ++KA P V+D +DP N Sbjct 525 LEKAFFTKQPVVMDFRVDPNEN 546 >gi|152905|gb|AAA26594.1| acetohydroxy acid synthase (AHAS) [Arthrospira platensis] Length=612 Score = 204 bits (520), Expect = 3e-50, Method: Compositional matrix adjust. Identities = 157/566 (28%), Positives = 259/566 (46%), Gaps = 35/566 (6%) Query 7 LVARMRAAGISVVCGLPTSRLDSLLVRLSR---DAGFQIVLARHEGGAGYLADGFARASG 63 L+ ++ G+ + G P + + L R + Q +L RHE GA + ADG+ARA+G Sbjct 18 LIDSLKRHGVQHIFGYPGGAILPIYDELYRAEAEGDIQHILVRHEQGASHAADGYARATG 77 Query 64 KSAAVF-VAGPGATNVISAVANASVNQVPMLILTGEVAVGEFGLHSQQDTSDDGLGLGAT 122 + F +GPGATN+++ +A A ++ +PM+I+TG+VA G + QD+ G+ L Sbjct 78 RVGVCFGTSGPGATNLVTGIATAHMDSIPMVIITGQVARPAIGTDAFQDSDIFGITL--- 134 Query 123 FRRFCRCSVSIESIANARSKIDSAFRALASIPRGPVHIALPRDLVDERLPAHQLGTAAAG 182 + S + + + AF ++ GPV I +P+D+ E + Sbjct 135 --PIVKHSYVVREPGDMARIVAEAFHIASTGRPGPVLIDVPKDVGLEEFDYIPVNPGEVS 192 Query 183 LGGLRTLAPCGPDVADEVIGRLDRSRAPMLVLGNGCRLDGIGEQIVAFCEKAGLPFATTP 242 L G R ++ I ++ + P++ +G G +I E +P TT Sbjct 193 LPGYRPTVKGNVRQINQAIKLIEEAERPLMYVGGGAISATAHAEIAELAELFQIPVTTTL 252 Query 243 NGRGIVAETHPLSLGVLGIFGDGRADEYLFDTPCDLLIAVGVSFGGLVTRSFSPRWRGLK 302 G+G E HPLS+G+LG+ G A+ + CD LIAVG F VT G + Sbjct 253 MGKGSFDEKHPLSVGMLGMHGTAYAN--FAVSECDFLIAVGARFDDRVTGKLDE--FGSR 308 Query 303 ADVVHVDPDPSAVGRFVATSLGITTSGRAFVNAL-----------NCGRPPRFCRRVGVR 351 A V+H+D DP+ VG+ + I R + L N + + R+ Sbjct 309 AKVIHIDIDPAEVGKNRTPEVPIVGDVRQVLIHLLRRCREIGDVGNDNQTQSWLERINRW 368 Query 352 PP-APAALPGTPQARGESIHPLELMHELDRELAPNATICADVGTCISWTFRGIPVRRPGR 410 P P +P + +S+ P E++ EL + +AP+ DVG W + + P + Sbjct 369 PEDYPLVVP----SYSDSLSPQEVIAELGK-MAPDGYYTTDVGQHQMWAAQFLK-NGPRQ 422 Query 411 FFATVDFSPMGCGIAGAIGVALARPEEHVICIAGDGAFLMHGTEISTAVAHGIRVTWAVL 470 + ++ MG GI A+G +A VICIAGD + M+ E+ T +GI V ++ Sbjct 423 WISSAGLGTMGYGIPSAMGAKVALERSQVICIAGDASVQMNIQELGTIAQYGINVKTVII 482 Query 471 ND---GQMSASAGPVSGRMDPSPVARIGANDLAAMARALGAEGIRVDTRCELRAGVQKAL 527 N+ G + G + IG D +AR+ G +G+ V +R EL + + L Sbjct 483 NNGWQGMVRQWQQAFYGERYSASNMEIGMPDFEMLARSYGVKGMVVKSRDELHQALAEML 542 Query 528 AATGPCVLDIAIDPEIN-KPDIGLGR 552 A GP ++D+ + + N P + GR Sbjct 543 AYDGPVLMDVHVTKDENCYPMVAPGR 568 >gi|56751375|ref|YP_172076.1| acetolactate synthase 3 catalytic subunit [Synechococcus elongatus PCC 6301] gi|56686334|dbj|BAD79556.1| acetolactate synthase [Synechococcus elongatus PCC 6301] Length=612 Score = 204 bits (519), Expect = 3e-50, Method: Compositional matrix adjust. Identities = 163/558 (30%), Positives = 255/558 (46%), Gaps = 36/558 (6%) Query 7 LVARMRAAGISVVCGLPTSRLDSLLVRLSRDAG---FQIVLARHEGGAGYLADGFARASG 63 L+ + G+ + G P + + L R Q +L RHE GA + AD ++RA+G Sbjct 18 LIDSLCQHGVKHIFGYPGGAILPIYDELHRAEAAGRVQHILVRHEQGAVHAADAYSRATG 77 Query 64 KSAAVF-VAGPGATNVISAVANASVNQVPMLILTGEVAVGEFGLHSQQDTSDDGLGLGAT 122 + F +GPGATN+++ +A A ++ +PM+++TG+V G + Q+T G+ L Sbjct 78 EVGVCFATSGPGATNLVTGIATAQMDSIPMVVVTGQVPRTAIGTDAFQETDIYGITLP-- 135 Query 123 FRRFCRCSVSIESIANARSKIDSAFRALASIPRGPVHIALPRDLVDERLPAHQLGTAAAG 182 + S + + + AF S GPV I +P+D+ E + Sbjct 136 ---IVKHSYVVRDPRDMARIVAEAFHIAQSGRPGPVLIDVPKDVGTEEFDYVPVAPGDIR 192 Query 183 LGGLRTLAPCGPDVADEVIGRLDRSRAPMLVLGNGCRLDGIGEQIVAFCEKAGLPFATTP 242 L G R P + I + +R P+L +G G G ++ AF E+ LP TT Sbjct 193 LPGYRPTTRGNPRQIAQAIALVRVARRPLLYVGGGAITAGAHAELRAFAERFQLPVTTTL 252 Query 243 NGRGIVAETHPLSLGVLGIFGDGRADEYLFDTPCDLLIAVGVSFGGLVTRSFSPRWRGLK 302 G+G E HPL+LG+LG+ G A+ + + CDLLIAVG F VT K Sbjct 253 MGKGAFDERHPLALGMLGMHGTAYANFAV--SECDLLIAVGARFDDRVTGKLDE--FASK 308 Query 303 ADVVHVDPDPSAVGRFVATSLGITTSGRAFVNAL-----------NCGRPPRFCRRVGV- 350 A V+HVD DP+ VG+ + I R +N L + R + R+ Sbjct 309 AQVIHVDIDPAEVGKNRVPEVPIVGDVRQVLNELLARAEEQISADDATRTQPWLDRIAYW 368 Query 351 RPPAPAALPGTPQARGESIHPLELMHELDRELAPNATICADVGTCISWTFRGIPVRRPGR 410 + P +P + + P +++H L E AP+A DVG W + I P R Sbjct 369 KREYPLQIP----YYADVLSPQQVIHSLG-EAAPDAYFTTDVGQHQMWAAQFIK-NGPRR 422 Query 411 FFATVDFSPMGCGIAGAIGVALARPEEHVICIAGDGAFLMHGTEISTAVAHGIRVTWAVL 470 + ++ MG G+ A+G +A P++ VIC+AGD + LM+ E+ T + I + V+ Sbjct 423 WISSAGLGTMGFGMPAAMGAQMALPDDTVICVAGDASILMNIQELGTLAQYNIPIKVVVV 482 Query 471 NDGQM----SASAGPVSGRMDPSPVARIGANDLAAMARALGAEGIRVDTRCELRAGVQKA 526 N+G R S + R G D +A A G +G+RV EL+A + + Sbjct 483 NNGWQGMVRQWQEAFYDERYSNSNMER-GMPDFVKLAEAFGIKGMRVSHPDELQAAIAEM 541 Query 527 LAATGPCVLDIAIDPEIN 544 LA GP LD + + N Sbjct 542 LAFDGPVFLDAIVKRDEN 559 >gi|118580972|ref|YP_902222.1| thiamine pyrophosphate binding domain-containing protein [Pelobacter propionicus DSM 2379] gi|118503682|gb|ABL00165.1| thiamine pyrophosphate enzyme TPP binding domain protein [Pelobacter propionicus DSM 2379] Length=573 Score = 204 bits (518), Expect = 4e-50, Method: Compositional matrix adjust. Identities = 171/583 (30%), Positives = 252/583 (44%), Gaps = 53/583 (9%) Query 1 VTVGDHLVARMRAAGISVVCGLPTSRLDSL---LVRLSRDAGFQIVLARHEGGAGYLADG 57 +TV D +V + G+ V G+P S L L LV + G ++VLARHE GA ++ADG Sbjct 3 LTVSDLIVEYLEQFGVEYVFGVPGSPLGPLFDALVCSEKRGGPRLVLARHEAGAAFMADG 62 Query 58 FARASGK-SAAVFVAGPGATNVISAVANASVNQVPMLILTGEVAVGEFGLHSQQDTSDDG 116 +AR SG+ GPGATN+I+ VA A QVPML+L+ + V +F QD+S DG Sbjct 63 YARESGRIGVCCSTTGPGATNLITGVAGAYAEQVPMLVLSSQTRVTDFSFGCFQDSSRDG 122 Query 117 LGLGATFRRFCRCSVSIESIANARSKIDSAFRALASIPRGPVHIALPRDLVDERLPAHQL 176 + + + F R + + K+ SA PRGP H+++P D+ Sbjct 123 VDIMSMFACCTRYNSLVSHPNQLEKKLASALTTALGSPRGPAHLSIPIDIFGAD------ 176 Query 177 GTAAAGLGGLRTLAPCGPDVAD-EVIGRLD------RSRAPMLVLGNGCRLDGIGEQIVA 229 + A GL +L D + RL RS + +VL G G+ I Sbjct 177 ASGPASYPGLHSLVSAEESTVDGAALERLMNEITTVRSTSGRIVLLAGANAISAGDLITR 236 Query 230 FCEKAGLPFATTPNGRGIVAETHPLSLGVLGIFGDGRADEYLFDTPCDLLIAVGVSFGGL 289 F E G TTP G+ + HPL+ GV G+ G A + L + L++AVG + G Sbjct 237 FAELTGAKIITTPRGKPAINPYHPLARGVFGVSGHSSARQTLAEDNVQLILAVGSNLGEW 296 Query 290 VTRSFSPRWRGLKADVVHVDPDPSAVGRFVATSLGITTSGRAFVNALNCGRPPR----FC 345 T + P + +VH+D D R L + A LN Sbjct 297 ETSKWDPIL--MNDCMVHIDSDRQNFTRSPMARLHLYGGIHAIFEQLNRRLEQHDGSAVS 354 Query 346 RRVGVRPPAPAA---LPG----------TPQARGESIHPLELMHELDRELAPNATICADV 392 R G APA +P P A G+ + ++ EL + L + D Sbjct 355 RSKGSAETAPATSAYVPAGISVRNADCCAPPASGQLLKAPQVYVELIQRLPRESRFFIDN 414 Query 393 GTCISWTFRGIPVRRPGRFFATVDFSPMGCGIAGAIGVALARPEEHVICIAGDGAFLMHG 452 + W+ +RP +++F+ M + A+G A A + +CIAGDG +LM G Sbjct 415 SNSVPWSIHYFFHQRPEALHYSIEFATMAWAVGAAVGGAFANQKAPSVCIAGDGCYLMSG 474 Query 453 TEISTAVAHGIRVTWAVLND--------GQMSASAGPVSGRMDPSPVARIGANDLAAMAR 504 EI+ AV + V +AVLND G + V + P D A MAR Sbjct 475 QEITVAVERRLPVIFAVLNDQAYGLIRHGHRTHGREAVDFSIPPV--------DFAMMAR 526 Query 505 ALGAEGIRVDTRCELRA-GVQKALAATGPCVLDIAIDPEINKP 546 + GA+ + + + QK GP +LD+ IDP+ P Sbjct 527 STGAQAFTIRSIEDFETIDWQKLATHQGPTLLDVTIDPKEPPP 569 >gi|126660706|ref|ZP_01731805.1| acetolactate synthase III large subunit [Cyanothece sp. CCY0110] gi|126618004|gb|EAZ88774.1| acetolactate synthase III large subunit [Cyanothece sp. CCY0110] Length=619 Score = 204 bits (518), Expect = 4e-50, Method: Compositional matrix adjust. Identities = 162/560 (29%), Positives = 256/560 (46%), Gaps = 40/560 (7%) Query 7 LVARMRAAGISVVCGLPTSRLDSLLVRLSRDAG---FQIVLARHEGGAGYLADGFARASG 63 L+ + G+ + G P + + L R Q L RHE GA + ADG+ARA+G Sbjct 25 LIDSLVRHGVKHIFGYPGGAILPIYDELYRAEARGDIQHFLVRHEQGASHAADGYARATG 84 Query 64 KSAAVF-VAGPGATNVISAVANASVNQVPMLILTGEVAVGEFGLHSQQDTSDDGLGLGAT 122 K F +GPGATN+++ +A A ++ +PM+++TG+VA G + Q+T G+ L Sbjct 85 KVGVCFGTSGPGATNLVTGIATAHLDSIPMVVVTGQVARAAIGSDAFQETDIFGITLP-- 142 Query 123 FRRFCRCSVSIESIANARSKIDSAFRALASIPRGPVHIALPRDLVDERLPAHQLGTAAAG 182 + S + + + S + AF ++ GPV I +P+D+ E + Sbjct 143 ---IVKHSYVVRNAEDMASIVAEAFHIASTGRPGPVLIDVPKDVGLEECDYIPVEPGQVK 199 Query 183 LGGLRTLAPCGPDVADEVIGRLDRSRAPMLVLGNGCRLDGIGEQIVAFCEKAGLPFATTP 242 L G R P + + ++ S P+L +G G Q+ E+ +P TT Sbjct 200 LPGYRPTVKGNPRQINAALSLIEVSERPLLYVGGGAIAANAHAQVQELAERFQIPVTTTL 259 Query 243 NGRGIVAETHPLSLGVLGIFGDGRADEYLFDTPCDLLIAVGVSFGGLVT---RSFSPRWR 299 G G E HPLS+G+LG+ G A+ + CDLLIAVG F VT F+ R R Sbjct 260 MGIGSFDEHHPLSVGMLGMHGTAYAN--FAVSECDLLIAVGSRFDDRVTGKLEEFASRAR 317 Query 300 GLKADVVHVDPDPSAVGRFVATSLGITTSGRAFVNAL-----------NCGRPPRFCRRV 348 V+H+D DP+ VG+ + I R + L + + + R+ Sbjct 318 -----VIHIDIDPAEVGKNRLPEVPIVGDVRQVLEQLLQRSREIDVPLDAEKTTPWLNRI 372 Query 349 G-VRPPAPAALPGTPQARGESIHPLELMHELDRELAPNATICADVGTCISWTFRGIPVRR 407 R P P SI P E++ E+ R+ AP+A DVG W + + Sbjct 373 NRWREQYPLTAP----HYDHSISPQEVIVEVGRQ-APHAYYTTDVGQHQMWAAQFLN-NG 426 Query 408 PGRFFATVDFSPMGCGIAGAIGVALARPEEHVICIAGDGAFLMHGTEISTAVAHGIRVTW 467 P R+ ++ MG G+ A+GV +A PEE VICI+GD +F M+ E++T + I Sbjct 427 PRRWISSAGLGTMGYGMPAALGVKVALPEEEVICISGDASFQMNLQELATLSQYNIAAKT 486 Query 468 AVLND---GQMSASAGPVSGRMDPSPVARIGANDLAAMARALGAEGIRVDTRCELRAGVQ 524 ++N+ G + G S + G D +A+A G +GI V +L V Sbjct 487 IIINNGWQGMVRQWQQTFFGERYSSSNMQTGMPDFELLAKAFGIKGITVREHSQLAGAVA 546 Query 525 KALAATGPCVLDIAIDPEIN 544 + LA GP ++D+ + + N Sbjct 547 EMLAHDGPVLMDVHVKRDEN 566 >gi|84488856|ref|YP_447088.1| IlvB1 [Methanosphaera stadtmanae DSM 3091] gi|84372175|gb|ABC56445.1| IlvB1 [Methanosphaera stadtmanae DSM 3091] Length=559 Score = 203 bits (517), Expect = 6e-50, Method: Compositional matrix adjust. Identities = 156/558 (28%), Positives = 255/558 (46%), Gaps = 47/558 (8%) Query 5 DHLVARMRAAGISVVCGLPTSRLDSLLVRLSRDAGFQIVLARHEGGAGYLADGFARASGK 64 D L+ +++ G V G P L L + D + +L RHE A + ADG+AR SGK Sbjct 5 DALLKKLKENGTDTVFGYPGGVLLPLYDSI-YDCDIKHILVRHEQAAAHAADGYARVSGK 63 Query 65 SAA-VFVAGPGATNVISAVANASVNQVPMLILTGEVAVGEFGLHSQQDTSDDGLGLGATF 123 + +GPGATN+++ +A A+++ P++ LTG+V G G + Q+ GL + T Sbjct 64 PGVCIATSGPGATNLVTGIATANIDSSPVIALTGQVTTGIIGTDAFQEVDTIGLTMPITK 123 Query 124 RRFC-RCSVSIESIANARSKIDSAFRALASIPRGPVHIALPRDLVDERLPAHQLGTAAAG 182 F R S + + ID+A+ ++ G V + LP+D++++ + + Sbjct 124 ENFQPRKSCDLPKV------IDAAYEIASTGRPGVVVVDLPKDVLEDEVSQEDM-KKVFD 176 Query 183 LGGLRTLAPCGPDVADEVIGRLDRSRAPMLVLGNGCRLDGIGEQIVAFCEKAGLPFATTP 242 L G + I + S+ P+++ G G L +++V F +P ATT Sbjct 177 LPGYKPTTTGNTRQIKRAIETIVESKKPVIIAGGGVILSNASDELVKFATLTNIPIATTL 236 Query 243 NGRGIVAETHPLSLGVLGIFGDGRADEYLFDTPCDLLIAVGVSFGGLVT---RSFSPRWR 299 G+G ++E H LSLG LG+ G + + D CD LIA+G F T F+P Sbjct 237 MGKGSISEDHELSLGHLGMHGLESTNNAVTD--CDCLIAIGCRFSDRTTGKVSEFAPN-- 292 Query 300 GLKADVVHVDPDPSAVGRFVATSLGIT----TSGRAFVNALNCGRPPRFCRRVGVRPPA- 354 A + +D DP+ +G+ V L I T R + LN ++ V + A Sbjct 293 ---ATKIQIDIDPAEIGKNVQIDLPIVGDAKTILRELIVELNETNHAKWTHDVINKHKAY 349 Query 355 -PAALPGTPQARGESIHPLELMHELDRELAPNATICADVGTCISWTFRGIPVRRPGRFFA 413 P T + P E + E+ + P + DVG W + P F + Sbjct 350 KPKMFFNT-----TPLKPQETIKEIMEAVTPTTIVSTDVGQNQMWMAHYYKTKNPRTFIS 404 Query 414 TVDFSPMGCGIAGAIGVALARPEEHVICIAGDGAFLMHGTEISTAVAHGIRVTWAVLND- 472 + MG G+ AIG +A+PEE+V+ + GDG F M E++T + + + VLN+ Sbjct 405 SGGLGTMGFGLPAAIGAQVAKPEENVLAVVGDGGFQMVSQELATIDEYDLPIVTCVLNNR 464 Query 473 -------GQMSASAGPVSG-RMDPSPVARIGANDLAAMARALGAEGIRVDTRCELRAGVQ 524 Q+ +S ++ P+P D +A++ G G RV+ ELR ++ Sbjct 465 YLGMVYQWQVLYYNERISQTKLKPTP-------DFVKLAQSYGVRGERVEKPGELRETIE 517 Query 525 KALAATGPCVLDIAIDPE 542 AL + V+D+ IDPE Sbjct 518 NALKSREATVIDVVIDPE 535 >gi|253689985|ref|YP_003019175.1| acetolactate synthase, large subunit, biosynthetic type [Pectobacterium carotovorum subsp. carotovorum PC1] gi|251756563|gb|ACT14639.1| acetolactate synthase, large subunit, biosynthetic type [Pectobacterium carotovorum subsp. carotovorum PC1] Length=554 Score = 203 bits (516), Expect = 7e-50, Method: Compositional matrix adjust. Identities = 165/560 (30%), Positives = 261/560 (47%), Gaps = 54/560 (9%) Query 4 GDHLVARM-RAAGISVVCGLPTSRLDSLLVRLSRDAGFQIVLARHEGGAGYLADGFARAS 62 G L+ R+ GIS V G+P L L + + VLARHE GAG++A G ARAS Sbjct 5 GAQLIVRLLEQQGISTVAGIPGGAALPLYDALGQSKTIRHVLARHEQGAGFMAQGMARAS 64 Query 63 GKSAAVFVA-GPGATNVISAVANASVNQVPMLILTGEVAVGEFGLHSQQDTSDDGLGLGA 121 G++A + GPGATN+++A+A+A ++ +P++ +TG+V G + Q+ G+ + Sbjct 65 GRAAVCMASSGPGATNLLTAIADAKLDSIPLVCITGQVPSSMIGTDAFQEVDTYGISIPV 124 Query 122 TFRRFCRCSVSIESIANARSKIDSAFRALASIPRGPVHIALPRDLVDERLPAHQLGTAAA 181 T + + I+ I AFR S GPV I +P+D+ + A Sbjct 125 TKHNYL-----VRDISELPRVIPEAFRIAQSGRPGPVWIDIPKDIQN----------ATI 169 Query 182 GLGGLRTLAPCG--PDVADEVIGR----LDRSRAPMLVLGNGCRLDGIGEQIVAFCEKAG 235 L L + P P +A + I R ++ ++ P+L LG G EQ V E++ Sbjct 170 ELSELPDVFPLDTPPTIAQQEIERAAAMINAAQRPVLYLGGGIISSAAHEQAVQLAERSS 229 Query 236 LPFATTPNGRGIVAETHPLSLGVLGIFGDGRADEYLFDTPCDLLIAVGVSFGGLV---TR 292 LP T G + HPLSLG+LG+ R+ + DLLI +G F Sbjct 230 LPTTMTLMALGAMPVDHPLSLGMLGMHA-ARSTNLILQQ-ADLLIVLGARFDDRAIGKAE 287 Query 293 SFSPRWRGLKADVVHVDPDPSAVGRFVATSLGITTSGRAFVNALNCGRPPRFCRRV---- 348 F P +A ++H+D DP+ +G+ + I ++ L P+ R V Sbjct 288 QFCP-----QASIIHIDIDPAELGKIRQPHVAINADVAQALDQLLPHITPQ-QRDVWRAT 341 Query 349 --GVRPPAPAALPGTPQARGESIHPLELMHELDRELAPNATICADVGTCISWTFRGIPVR 406 G++ P ++P + + L+ R L +A I DVG W + P+R Sbjct 342 VSGLQQEFPFSMPNA----DDPLSHYGLVQATARALTDDAIITTDVGQHQMWVAQSYPLR 397 Query 407 RPGRFFATVDFSPMGCGIAGAIGVALARPEEHVICIAGDGAFLMHGTEISTAVAHGIRVT 466 RP ++ + F MG G+ AIG ALA PE V+C +GDG+ +M+ E++TA G+ V Sbjct 398 RPRQWLTSGGFGTMGFGLPAAIGAALAEPERTVVCFSGDGSLMMNIQEMATAAEEGLNVK 457 Query 467 WAVLNDGQMSASAGPVSGRMDPSPVARIGAND------LAAMARALGAEGIRVDTRCELR 520 ++N+ S G V + D RI A D A+A G ++ + + Sbjct 458 IVLMNN----QSLGLVHQQQDMFFQQRIFAADYRYSTNFLAIAAGFGFATCDLNAAADPQ 513 Query 521 AGVQKALAATGPCVLDIAID 540 A +Q+AL GP ++ + ID Sbjct 514 AALQEALNQPGPALIHVLID 533 >gi|16330569|ref|NP_441297.1| acetolactate synthase 3 catalytic subunit [Synechocystis sp. PCC 6803] gi|1653060|dbj|BAA17977.1| acetohydroxy acid synthase [Synechocystis sp. PCC 6803] gi|339273662|dbj|BAK50149.1| acetolactate synthase 3 catalytic subunit [Synechocystis sp. PCC 6803] Length=621 Score = 203 bits (516), Expect = 7e-50, Method: Compositional matrix adjust. Identities = 167/550 (31%), Positives = 258/550 (47%), Gaps = 44/550 (8%) Query 7 LVARMRAAGISVVCGLPTSRLDSL---LVRLSRDAGFQIVLARHEGGAGYLADGFARASG 63 L+ ++ G+ + G P + + L R + +L RHE GA + ADG+ARA+G Sbjct 27 LMDSLKRHGVKHIFGYPGGAILPIYDELYRFEAAGEIEHILVRHEQGASHAADGYARATG 86 Query 64 KSAAVF-VAGPGATNVISAVANASVNQVPMLILTGEVAVGEFGLHSQQDTSDDGLGLGAT 122 K F +GPGATN+++ +ANA ++ VPM+++TG+V G + Q+ G+ L Sbjct 87 KVGVCFGTSGPGATNLVTGIANAHLDSVPMVVITGQVGRAMIGSDAFQEIDIFGITL--- 143 Query 123 FRRFCRCSVSIESIANARSKIDSAFRALASIPR-GPVHIALPRDLVDERLPAHQLGTAAA 181 + S + S A+ + AF LAS R GPV I +P+D+ E L Sbjct 144 --PIVKHSYVVRSAADMARIVTEAFH-LASTGRPGPVLIDIPKDVGLEECEYIPLDPGDV 200 Query 182 GLGGLRTLAPCGPDVADEVIGRLDRSRAPMLVLGNGCRLDGIGEQIVAFCEKAGLPFATT 241 L G R P + + L+++R P+L +G G Q+ F E+ LP TT Sbjct 201 NLPGYRPTVKGNPRQINAALQLLEQARNPLLYVGGGAIAANAHAQVQEFAERFQLPVTTT 260 Query 242 PNGRGIVAETHPLSLGVLGIFGDGRADEYLFDTPCDLLIAVGVSFGGLVT---RSFSPRW 298 G G E HPLS+G+LG+ G A+ + + CDLLIAVG F VT F+ R Sbjct 261 LMGIGAFDENHPLSVGMLGMHGTAYANFAV--SECDLLIAVGARFDDRVTGKLDEFASR- 317 Query 299 RGLKADVVHVDPDPSAVGRFVATSLGITTSGRAFVNAL-----NCGRPPR------FCRR 347 A V+H+D DP+ VG+ A + I R + L P + R Sbjct 318 ----AKVIHIDIDPAEVGKNRAPDVPIVGDVRHVLEQLLQRARELDYPTHPHTTQAWLNR 373 Query 348 VG-VRPPAPAALPGTPQARGESIHPLELMHELDRELAPNATICADVGTCISWTFRGIPVR 406 + R P +P ++I P E++HE+ R+ AP+A DVG W + + Sbjct 374 IDHWRTDYPLQVPHYE----DTIAPQEVVHEIGRQ-APDAYYTTDVGQHQMWAAQFLN-N 427 Query 407 RPGRFFATVDFSPMGCGIAGAIGVALARPEEHVICIAGDGAFLMHGTEISTAVAHGIRVT 466 P R+ ++ MG G+ A+G + +E VICI+GD +F M+ E+ T + I+V Sbjct 428 GPRRWISSAGLGTMGFGLPAAMGAKVGVGDEAVICISGDASFQMNLQELGTLAQYDIQVK 487 Query 467 WAVLNDGQM----SASAGPVSGRMDPSPVARIGANDLAAMARALGAEGIRVDTRCELRAG 522 +LN+G R S +++ G D+ + A G +GI V R +L Sbjct 488 TIILNNGWQGMVRQWQQTFYEERYSASNMSQ-GMPDINLLCEAYGIKGITVRKREDLAPA 546 Query 523 VQKALAATGP 532 + + LA GP Sbjct 547 IAEMLAHNGP 556 >gi|307719394|ref|YP_003874926.1| acetolactate synthase large subunit [Spirochaeta thermophila DSM 6192] gi|306533119|gb|ADN02653.1| acetolactate synthase large subunit [Spirochaeta thermophila DSM 6192] Length=571 Score = 202 bits (515), Expect = 1e-49, Method: Compositional matrix adjust. Identities = 151/542 (28%), Positives = 261/542 (49%), Gaps = 32/542 (5%) Query 15 GISVVCGLP----TSRLDSLLVRLSRDAGFQIVLARHEGGAGYLADGFARASGKSAAVFV 70 G+ + G+P D+L+ D+G + +L RHE GA ++ADG+ARASGK+A V V Sbjct 20 GVEYIFGIPGGAAIPLYDALV-----DSGIKFILTRHEQGATHMADGYARASGKAAVVLV 74 Query 71 -AGPGATNVISAVANASVNQVPMLILTGEVAVGEFGLHSQQDTSDDGLGLGATFRRFCRC 129 +GPGATN ++ + A ++ P++++TG+ GL + Q+ G+ + Sbjct 75 TSGPGATNTVTGIFTAYMDSSPVVVITGQQTRNNLGLDAFQEADVSGITYP-----IVKH 129 Query 130 SVSIESIANARSKIDSAFRALASIPRGPVHIALPRDLVDERLPAHQLGTAAAGLGGLRTL 189 S +++ + AF + GPV I +P+D+ + P L G + Sbjct 130 SYLVKNAKELPRIVREAFHLATTGRPGPVLIDIPKDVSN--TPIEPDYDEEFHLEGYKVQ 187 Query 190 APCGPDVADEVIGRLDRSRAPMLVLGNGCRLDGIGEQIVAFCEKAGLPFATTPNGRGIVA 249 + +E L ++ P+L++G+G + G + + EK +P TT G+G Sbjct 188 IEGDMEKIEEAARLLQEAKRPVLLVGHGAIISGAEKAVRQLAEKLQIPVTTTLLGKGAFP 247 Query 250 ETHPLSLGVLGIFGDGRADEYLFDTPCDLLIAVGVSFGGLVTRSFSPRWRGLKADVVHVD 309 ETH LSLG+LG+ G A+ + + CDL++++G + +T S R+ + A +H+D Sbjct 248 ETHELSLGMLGMHGTAYANMAVDN--CDLIVSIGSRWDDRITGDVS-RF-CVNAKKIHID 303 Query 310 PDPSAVGRFVATSLGITTSGRAFVNAL----NCGRPPRFCRRVGVRPPAPAALPGTPQAR 365 DP+ + + + +GI R V AL G + +++ R L + + Sbjct 304 IDPAEINKIIKVDVGIVGDARHVVEALVGITRRGDTTDWLKQIN-RWKRQYPLKYRKEGK 362 Query 366 GESIHPLELMHELDRELAPNATICADVGTCISWTFRGIPVRRPGRFFATVDFSPMGCGIA 425 ++ H +E EL R+ A + DVG W + V P + ++ MG G+ Sbjct 363 LKAQHVIE---ELYRQTGGKAVVVTDVGQHQMWAAQYYKVDSPRNWISSGGAGTMGFGLP 419 Query 426 GAIGVALARPEEHVICIAGDGAFLMHGTEISTAVAHGIRVTWAVLNDGQ--MSASAGPVS 483 AIG ARP+E V+ I GDG F M E++TAV H + + V+N+ M + Sbjct 420 AAIGAQFARPDETVVAIVGDGGFQMTFFELATAVIHKLPIKIVVINNRYLGMVRQWQHLF 479 Query 484 GRMDPSPVARIGANDLAAMARALGAEGIRVDTRCELRAGVQKALAAT-GPCVLDIAIDPE 542 S V G+ D +AR+ G + R+ +++ V++AL+ GPC++D ++ E Sbjct 480 YENRLSGVDLEGSPDFVKLARSFGCKAFRLRRPGDVKRVVEQALSYNDGPCLIDAEVEKE 539 Query 543 IN 544 N Sbjct 540 EN 541 >gi|317487960|ref|ZP_07946544.1| acetolactate synthase [Eggerthella sp. 1_3_56FAA] gi|316912942|gb|EFV34467.1| acetolactate synthase [Eggerthella sp. 1_3_56FAA] Length=630 Score = 201 bits (512), Expect = 2e-49, Method: Compositional matrix adjust. Identities = 165/573 (29%), Positives = 266/573 (47%), Gaps = 52/573 (9%) Query 7 LVARMRAAGISVVCGLPTSRLDSLLVRLSRDAGFQIVLARHEGGAGYLADGFARASGKSA 66 +VA + A G+ +V G P + + L + VLARHE GA + ADG+ARA+G Sbjct 47 VVASLEAEGVDLVFGYPGGQAIKIYDALYDSDQIKHVLARHEQGAVHEADGYARATGNVG 106 Query 67 AVFV-AGPGATNVISAVANASVNQVPMLILTGEVAVGEFGLHSQQDTSDDGLGLGATFRR 125 V V +GPGATN ++ +A A ++ VP++++TG+V G G S Q++ G+ + Sbjct 107 VVIVTSGPGATNTVTGIATAYMDSVPLVVITGQVPRGVIGTDSFQESDIVGITM-----P 161 Query 126 FCRCSVSIESIANARSKIDSAFRALASIPRGPVHIALPRDLVDERLPAHQLGTAAAGLGG 185 + S ++S + AF + GPV I +P DL E + Sbjct 162 VVKHSYLLQSTDELTTTFREAFHIAKTGRPGPVLIDVPSDLASELMTFEYPDDV-----N 216 Query 186 LRTLAPCGPDVADEV---IGRLDRSRAPMLVLGNGCRLDGIGEQIVAFCEKAGLPFATTP 242 L + P A ++ + R+ ++ P+L +G G G E++ A E +P TT Sbjct 217 LPSYKPTYRGNAKQIKQAVSRIKQAERPVLYVGGGTVSSGASEELKALAELMQIPVVTTL 276 Query 243 NGRGIVAETHPLSLGVLGIFGDGRADEYLFDTPCDLLIAVGVSFGGLVT---RSFSPRWR 299 G+G +H L+LG +G+ G A+ L T DL+IA G F VT F+P Sbjct 277 MGKGAFPASHELNLGPVGMHGSKYAN--LAMTESDLIIAAGARFSDRVTGKLDEFAPH-- 332 Query 300 GLKADVVHVDPDPSAVGRFVATSLGITTSGRAFVNAL------NCGRP--PRFCRRVGV- 350 ADV+H+D DP+ +G+ + I + + + RP + ++ Sbjct 333 ---ADVIHIDIDPAEIGKVREVQVPIVGDLKGVLAGIVSTLEKEGARPGTGTWVEQISAW 389 Query 351 RPPAPAALPGTPQARGESIHPLELMHELDRELAP-NATICADVGTCISWTFRGIPVRRPG 409 R P PG E I P ++ +L L P N+ + +VG W + + P Sbjct 390 RTRYPFYHPGVGDDPDE-IVPEVVLKKLSESLDPQNSVVVTEVGQHQMWAAQSVDREAPR 448 Query 410 RFFATVDFSPMGCGIAGAIGVALARPEEHVICIAGDGAFLMHGTEISTAVAHGIRVTWAV 469 F ++ MG G AIG A+ PE+ V+C+AGDG+F M+ E++TA H + V + Sbjct 449 SFLSSGGLGTMGFGFPAAIGAAIGCPEKQVVCVAGDGSFQMNSQEMATASIHRVPVKVLI 508 Query 470 LND---------GQMSASAGPVSGRMDPSPVARIGANDLAAMARALGAEGIRVDTRCELR 520 L++ ++ S +D SP D +A A G +G RV+ ++ Sbjct 509 LDNRCLGMVHQWQKLFYDERYSSTLLDASP-------DFVKLAEAYGWQGERVEKPADVD 561 Query 521 AGVQKALAATGPCVLDIAIDPEIN-KPDIGLGR 552 A + + LA+ GP +LD+AI + N P + GR Sbjct 562 AALARMLASDGPYLLDVAISRDQNVYPMVAPGR 594 >gi|339412483|gb|AEJ62048.1| acetolactate synthase, large subunit, biosynthetic type [Spirochaeta thermophila DSM 6578] Length=571 Score = 201 bits (512), Expect = 2e-49, Method: Compositional matrix adjust. Identities = 150/542 (28%), Positives = 260/542 (48%), Gaps = 32/542 (5%) Query 15 GISVVCGLP----TSRLDSLLVRLSRDAGFQIVLARHEGGAGYLADGFARASGKSAAVFV 70 G+ + G+P D+L+ D+G + +L RHE GA ++ADG+ARASGK+A V V Sbjct 20 GVEYIFGIPGGAAIPLYDALV-----DSGIKFILTRHEQGATHMADGYARASGKAAVVLV 74 Query 71 -AGPGATNVISAVANASVNQVPMLILTGEVAVGEFGLHSQQDTSDDGLGLGATFRRFCRC 129 +GPGATN ++ + A ++ P++++TG+ GL + Q+ G+ + Sbjct 75 TSGPGATNTVTGIFTAYMDSSPVVVITGQQTRNNLGLDAFQEADVSGITYP-----IVKH 129 Query 130 SVSIESIANARSKIDSAFRALASIPRGPVHIALPRDLVDERLPAHQLGTAAAGLGGLRTL 189 S ++ + AF + GP+ I +P+D+ + + L G + Sbjct 130 SYLVKDPKELPRIVREAFHLATTGRPGPILIDIPKDISNSLIEPDY--DEEFHLEGYKVQ 187 Query 190 APCGPDVADEVIGRLDRSRAPMLVLGNGCRLDGIGEQIVAFCEKAGLPFATTPNGRGIVA 249 + +E L ++ P+L++G+G + G + + EK +P TT G+G Sbjct 188 VEGDTEKIEEAARLLHEAKRPVLLVGHGAIISGAEKAVRHLAEKLQIPVTTTLLGKGAFP 247 Query 250 ETHPLSLGVLGIFGDGRADEYLFDTPCDLLIAVGVSFGGLVTRSFSPRWRGLKADVVHVD 309 ETH LSLG+LG+ G A+ + + CDL++++G + +T S R+ + A +H+D Sbjct 248 ETHELSLGMLGMHGTAYANMAVDN--CDLIVSIGSRWDDRITGDVS-RF-CVNAKKIHID 303 Query 310 PDPSAVGRFVATSLGITTSGRAFVNAL----NCGRPPRFCRRVGVRPPAPAALPGTPQAR 365 DP+ + + + +GI R V AL G + +++ R L + + Sbjct 304 IDPAEINKIIKVDVGIVGDARHVVEALAGISRRGDTTDWLKQIN-RWKRQYPLKYRKEGK 362 Query 366 GESIHPLELMHELDRELAPNATICADVGTCISWTFRGIPVRRPGRFFATVDFSPMGCGIA 425 ++ H +E EL R+ A + DVG W + V P + ++ MG G+ Sbjct 363 LKAQHVIE---ELYRQTGGKAVVVTDVGQHQMWAAQYYKVDSPRNWISSGGAGTMGFGLP 419 Query 426 GAIGVALARPEEHVICIAGDGAFLMHGTEISTAVAHGIRVTWAVLNDGQ--MSASAGPVS 483 AIG ARP+E V+ I GDG F M E++TAV H + + V+N+ M + Sbjct 420 AAIGAQFARPDETVVAIVGDGGFQMTFFELATAVIHRLPIKIVVINNRYLGMVRQWQHLF 479 Query 484 GRMDPSPVARIGANDLAAMARALGAEGIRVDTRCELRAGVQKALAAT-GPCVLDIAIDPE 542 S V G+ D +AR+ G + R+ ++R V++AL+ GPC++D ++ E Sbjct 480 YENRLSGVDLEGSPDFVKLARSFGCKAFRLRRPGDVRRVVEQALSYNDGPCLIDAEVEKE 539 Query 543 IN 544 N Sbjct 540 EN 541 Lambda K H 0.322 0.139 0.425 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 1225712359146 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40