BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv3524 Length=343 Score E Sequences producing significant alignments: (Bits) Value gi|15610660|ref|NP_218041.1| hypothetical protein Rv3524 [Mycoba... 683 0.0 gi|340628488|ref|YP_004746940.1| hypothetical protein MCAN_35351... 681 0.0 gi|167969134|ref|ZP_02551411.1| hypothetical protein MtubH3_1432... 555 4e-156 gi|294993642|ref|ZP_06799333.1| hypothetical protein Mtub2_03816... 554 8e-156 gi|308232490|ref|ZP_07416211.2| conserved membrane protein [Myco... 483 1e-134 gi|183984980|ref|YP_001853271.1| hypothetical protein MMAR_5012 ... 320 1e-85 gi|183984979|ref|YP_001853270.1| hypothetical protein MMAR_5011 ... 293 2e-77 gi|240172359|ref|ZP_04751018.1| hypothetical protein MkanA1_2379... 273 4e-71 gi|183982552|ref|YP_001850843.1| hypothetical protein MMAR_2539 ... 216 3e-54 gi|183983388|ref|YP_001851679.1| transmembrane serine/threonine-... 207 2e-51 gi|333992173|ref|YP_004524787.1| serine/threonine-protein kinase... 204 2e-50 gi|298524423|ref|ZP_07011832.1| transmembrane serine/threonine-p... 203 4e-50 gi|31792118|ref|NP_854611.1| serine/threonine protein kinase D [... 203 4e-50 gi|339630994|ref|YP_004722636.1| Ser/Thr protein kinase D [Mycob... 202 4e-50 gi|289446501|ref|ZP_06436245.1| transmembrane serine/threonine-p... 202 5e-50 gi|254549912|ref|ZP_05140359.1| transmembrane serine/threonine-p... 202 5e-50 gi|15608071|ref|NP_215446.1| transmembrane serine/threonine-prot... 202 5e-50 gi|289442346|ref|ZP_06432090.1| transmembrane serine/threonine-p... 202 8e-50 gi|183984546|ref|YP_001852837.1| transmembrane serine/threonine-... 197 2e-48 gi|240170121|ref|ZP_04748780.1| transmembrane serine/threonine-p... 194 2e-47 gi|342861478|ref|ZP_08718125.1| PknD [Mycobacterium colombiense ... 193 3e-47 gi|240171930|ref|ZP_04750589.1| transmembrane serine/threonine-p... 193 3e-47 gi|254819498|ref|ZP_05224499.1| PknD [Mycobacterium intracellula... 189 7e-46 gi|240172492|ref|ZP_04751151.1| transmembrane serine/threonine-p... 187 1e-45 gi|333991664|ref|YP_004524278.1| serine/threonine-protein kinase... 187 2e-45 gi|48425401|pdb|1RWI|B Chain B, Extracellular Domain Of Mycobact... 187 2e-45 gi|306775061|ref|ZP_07413398.1| transmembrane serine/threonine-p... 187 2e-45 gi|111026929|ref|YP_708907.1| protein kinase [Rhodococcus jostii... 184 3e-44 gi|254776673|ref|ZP_05218189.1| serine/threonine-protein kinase ... 183 3e-44 gi|240170030|ref|ZP_04748689.1| transmembrane serine/threonine-p... 179 5e-43 gi|118465473|ref|YP_883379.1| serine/threonine protein kinase [M... 179 8e-43 gi|111025322|ref|YP_707742.1| serine/threonine protein kinase [R... 178 1e-42 gi|41409485|ref|NP_962321.1| PknD [Mycobacterium avium subsp. pa... 177 2e-42 gi|296168857|ref|ZP_06850529.1| possible non-specific serine/thr... 160 2e-37 gi|111017527|ref|YP_700499.1| serine/threonine-protein kinase [R... 160 3e-37 gi|296170643|ref|ZP_06852218.1| non-specific serine/threonine pr... 154 1e-35 gi|226363603|ref|YP_002781385.1| serine/threonine protein kinase... 150 3e-34 gi|111021257|ref|YP_704229.1| protein kinase [Rhodococcus jostii... 145 1e-32 gi|336459649|gb|EGO38584.1| NHL repeat protein,protein kinase fa... 132 9e-29 gi|254383857|ref|ZP_04999204.1| serine/threonine-protein kinase ... 131 2e-28 gi|291442837|ref|ZP_06582227.1| serine/threonine-protein kinase ... 127 2e-27 gi|239985881|ref|ZP_04706545.1| hypothetical protein SrosN1_0110... 125 7e-27 gi|326780986|ref|ZP_08240251.1| NHL repeat containing protein [S... 122 7e-26 gi|182440319|ref|YP_001828038.1| hypothetical protein SGR_6526 [... 122 9e-26 gi|219852087|ref|YP_002466519.1| NHL repeat containing protein [... 112 6e-23 gi|322435783|ref|YP_004217995.1| cell surface receptor IPT/TIG [... 108 1e-21 gi|111025317|ref|YP_707737.1| hypothetical protein RHA1_ro08535 ... 108 1e-21 gi|284039570|ref|YP_003389500.1| NHL repeat containing protein [... 105 1e-20 gi|73667964|ref|YP_303979.1| hypothetical protein Mbar_A0416 [Me... 103 4e-20 gi|299137977|ref|ZP_07031157.1| NHL repeat containing protein [A... 102 7e-20 >gi|15610660|ref|NP_218041.1| hypothetical protein Rv3524 [Mycobacterium tuberculosis H37Rv] gi|15843134|ref|NP_338171.1| hypothetical protein MT3624 [Mycobacterium tuberculosis CDC1551] gi|31794700|ref|NP_857193.1| hypothetical protein Mb3554 [Mycobacterium bovis AF2122/97] 51 more sequence titles Length=343 Score = 683 bits (1762), Expect = 0.0, Method: Compositional matrix adjust. Identities = 343/343 (100%), Positives = 343/343 (100%), Gaps = 0/343 (0%) Query 1 MVKFTPDSQTSVLRAGKCSGTLSPSRSRLQRGSWPVDSERRRYGWPRNRRTLAITGAAVV 60 MVKFTPDSQTSVLRAGKCSGTLSPSRSRLQRGSWPVDSERRRYGWPRNRRTLAITGAAVV Sbjct 1 MVKFTPDSQTSVLRAGKCSGTLSPSRSRLQRGSWPVDSERRRYGWPRNRRTLAITGAAVV 60 Query 61 VVVTLAAIGYLIFEPKISGSSTSRQAASPTTPSPPSQVVVPIDLWNPDGVTVDLADAVYV 120 VVVTLAAIGYLIFEPKISGSSTSRQAASPTTPSPPSQVVVPIDLWNPDGVTVDLADAVYV Sbjct 61 VVVTLAAIGYLIFEPKISGSSTSRQAASPTTPSPPSQVVVPIDLWNPDGVTVDLADAVYV 120 Query 121 ADSGHKRLLKLPAGSNTPTTLPFTDTIGPGGVAVNSNRDVYVIDEDSHHVLKLAAGIEPP 180 ADSGHKRLLKLPAGSNTPTTLPFTDTIGPGGVAVNSNRDVYVIDEDSHHVLKLAAGIEPP Sbjct 121 ADSGHKRLLKLPAGSNTPTTLPFTDTIGPGGVAVNSNRDVYVIDEDSHHVLKLAAGIEPP 180 Query 181 VELPFGSLGDAHGLAVDRSDSVYVVDYDNAKVLKLPPGADTPTELPFVGLDHPYDVAVDG 240 VELPFGSLGDAHGLAVDRSDSVYVVDYDNAKVLKLPPGADTPTELPFVGLDHPYDVAVDG Sbjct 181 VELPFGSLGDAHGLAVDRSDSVYVVDYDNAKVLKLPPGADTPTELPFVGLDHPYDVAVDG 240 Query 241 AGTVYVTDSGHNRVVALTAGSATPVHLPFADLSFPAGVTVDRDDSVYVADLNNNRVLKLA 300 AGTVYVTDSGHNRVVALTAGSATPVHLPFADLSFPAGVTVDRDDSVYVADLNNNRVLKLA Sbjct 241 AGTVYVTDSGHNRVVALTAGSATPVHLPFADLSFPAGVTVDRDDSVYVADLNNNRVLKLA 300 Query 301 AGSNAQSQLPFTGLFSPTDVAVDNDGAVYVIDFYNRMLKLPTA 343 AGSNAQSQLPFTGLFSPTDVAVDNDGAVYVIDFYNRMLKLPTA Sbjct 301 AGSNAQSQLPFTGLFSPTDVAVDNDGAVYVIDFYNRMLKLPTA 343 >gi|340628488|ref|YP_004746940.1| hypothetical protein MCAN_35351 [Mycobacterium canettii CIPT 140010059] gi|340006678|emb|CCC45866.1| putative conserved membrane protein [Mycobacterium canettii CIPT 140010059] Length=343 Score = 681 bits (1756), Expect = 0.0, Method: Compositional matrix adjust. Identities = 342/343 (99%), Positives = 342/343 (99%), Gaps = 0/343 (0%) Query 1 MVKFTPDSQTSVLRAGKCSGTLSPSRSRLQRGSWPVDSERRRYGWPRNRRTLAITGAAVV 60 MVKFTPDSQTSVLRAGKCSGTLSPSRSRLQRGSWPVDSERRRYGWPRNR TLAITGAAVV Sbjct 1 MVKFTPDSQTSVLRAGKCSGTLSPSRSRLQRGSWPVDSERRRYGWPRNRCTLAITGAAVV 60 Query 61 VVVTLAAIGYLIFEPKISGSSTSRQAASPTTPSPPSQVVVPIDLWNPDGVTVDLADAVYV 120 VVVTLAAIGYLIFEPKISGSSTSRQAASPTTPSPPSQVVVPIDLWNPDGVTVDLADAVYV Sbjct 61 VVVTLAAIGYLIFEPKISGSSTSRQAASPTTPSPPSQVVVPIDLWNPDGVTVDLADAVYV 120 Query 121 ADSGHKRLLKLPAGSNTPTTLPFTDTIGPGGVAVNSNRDVYVIDEDSHHVLKLAAGIEPP 180 ADSGHKRLLKLPAGSNTPTTLPFTDTIGPGGVAVNSNRDVYVIDEDSHHVLKLAAGIEPP Sbjct 121 ADSGHKRLLKLPAGSNTPTTLPFTDTIGPGGVAVNSNRDVYVIDEDSHHVLKLAAGIEPP 180 Query 181 VELPFGSLGDAHGLAVDRSDSVYVVDYDNAKVLKLPPGADTPTELPFVGLDHPYDVAVDG 240 VELPFGSLGDAHGLAVDRSDSVYVVDYDNAKVLKLPPGADTPTELPFVGLDHPYDVAVDG Sbjct 181 VELPFGSLGDAHGLAVDRSDSVYVVDYDNAKVLKLPPGADTPTELPFVGLDHPYDVAVDG 240 Query 241 AGTVYVTDSGHNRVVALTAGSATPVHLPFADLSFPAGVTVDRDDSVYVADLNNNRVLKLA 300 AGTVYVTDSGHNRVVALTAGSATPVHLPFADLSFPAGVTVDRDDSVYVADLNNNRVLKLA Sbjct 241 AGTVYVTDSGHNRVVALTAGSATPVHLPFADLSFPAGVTVDRDDSVYVADLNNNRVLKLA 300 Query 301 AGSNAQSQLPFTGLFSPTDVAVDNDGAVYVIDFYNRMLKLPTA 343 AGSNAQSQLPFTGLFSPTDVAVDNDGAVYVIDFYNRMLKLPTA Sbjct 301 AGSNAQSQLPFTGLFSPTDVAVDNDGAVYVIDFYNRMLKLPTA 343 >gi|167969134|ref|ZP_02551411.1| hypothetical protein MtubH3_14320 [Mycobacterium tuberculosis H37Ra] Length=282 Score = 555 bits (1430), Expect = 4e-156, Method: Compositional matrix adjust. Identities = 281/282 (99%), Positives = 282/282 (100%), Gaps = 0/282 (0%) Query 62 VVTLAAIGYLIFEPKISGSSTSRQAASPTTPSPPSQVVVPIDLWNPDGVTVDLADAVYVA 121 +VTLAAIGYLIFEPKISGSSTSRQAASPTTPSPPSQVVVPIDLWNPDGVTVDLADAVYVA Sbjct 1 MVTLAAIGYLIFEPKISGSSTSRQAASPTTPSPPSQVVVPIDLWNPDGVTVDLADAVYVA 60 Query 122 DSGHKRLLKLPAGSNTPTTLPFTDTIGPGGVAVNSNRDVYVIDEDSHHVLKLAAGIEPPV 181 DSGHKRLLKLPAGSNTPTTLPFTDTIGPGGVAVNSNRDVYVIDEDSHHVLKLAAGIEPPV Sbjct 61 DSGHKRLLKLPAGSNTPTTLPFTDTIGPGGVAVNSNRDVYVIDEDSHHVLKLAAGIEPPV 120 Query 182 ELPFGSLGDAHGLAVDRSDSVYVVDYDNAKVLKLPPGADTPTELPFVGLDHPYDVAVDGA 241 ELPFGSLGDAHGLAVDRSDSVYVVDYDNAKVLKLPPGADTPTELPFVGLDHPYDVAVDGA Sbjct 121 ELPFGSLGDAHGLAVDRSDSVYVVDYDNAKVLKLPPGADTPTELPFVGLDHPYDVAVDGA 180 Query 242 GTVYVTDSGHNRVVALTAGSATPVHLPFADLSFPAGVTVDRDDSVYVADLNNNRVLKLAA 301 GTVYVTDSGHNRVVALTAGSATPVHLPFADLSFPAGVTVDRDDSVYVADLNNNRVLKLAA Sbjct 181 GTVYVTDSGHNRVVALTAGSATPVHLPFADLSFPAGVTVDRDDSVYVADLNNNRVLKLAA 240 Query 302 GSNAQSQLPFTGLFSPTDVAVDNDGAVYVIDFYNRMLKLPTA 343 GSNAQSQLPFTGLFSPTDVAVDNDGAVYVIDFYNRMLKLPTA Sbjct 241 GSNAQSQLPFTGLFSPTDVAVDNDGAVYVIDFYNRMLKLPTA 282 >gi|294993642|ref|ZP_06799333.1| hypothetical protein Mtub2_03816 [Mycobacterium tuberculosis 210] Length=281 Score = 554 bits (1427), Expect = 8e-156, Method: Compositional matrix adjust. Identities = 280/281 (99%), Positives = 281/281 (100%), Gaps = 0/281 (0%) Query 63 VTLAAIGYLIFEPKISGSSTSRQAASPTTPSPPSQVVVPIDLWNPDGVTVDLADAVYVAD 122 +TLAAIGYLIFEPKISGSSTSRQAASPTTPSPPSQVVVPIDLWNPDGVTVDLADAVYVAD Sbjct 1 MTLAAIGYLIFEPKISGSSTSRQAASPTTPSPPSQVVVPIDLWNPDGVTVDLADAVYVAD 60 Query 123 SGHKRLLKLPAGSNTPTTLPFTDTIGPGGVAVNSNRDVYVIDEDSHHVLKLAAGIEPPVE 182 SGHKRLLKLPAGSNTPTTLPFTDTIGPGGVAVNSNRDVYVIDEDSHHVLKLAAGIEPPVE Sbjct 61 SGHKRLLKLPAGSNTPTTLPFTDTIGPGGVAVNSNRDVYVIDEDSHHVLKLAAGIEPPVE 120 Query 183 LPFGSLGDAHGLAVDRSDSVYVVDYDNAKVLKLPPGADTPTELPFVGLDHPYDVAVDGAG 242 LPFGSLGDAHGLAVDRSDSVYVVDYDNAKVLKLPPGADTPTELPFVGLDHPYDVAVDGAG Sbjct 121 LPFGSLGDAHGLAVDRSDSVYVVDYDNAKVLKLPPGADTPTELPFVGLDHPYDVAVDGAG 180 Query 243 TVYVTDSGHNRVVALTAGSATPVHLPFADLSFPAGVTVDRDDSVYVADLNNNRVLKLAAG 302 TVYVTDSGHNRVVALTAGSATPVHLPFADLSFPAGVTVDRDDSVYVADLNNNRVLKLAAG Sbjct 181 TVYVTDSGHNRVVALTAGSATPVHLPFADLSFPAGVTVDRDDSVYVADLNNNRVLKLAAG 240 Query 303 SNAQSQLPFTGLFSPTDVAVDNDGAVYVIDFYNRMLKLPTA 343 SNAQSQLPFTGLFSPTDVAVDNDGAVYVIDFYNRMLKLPTA Sbjct 241 SNAQSQLPFTGLFSPTDVAVDNDGAVYVIDFYNRMLKLPTA 281 >gi|308232490|ref|ZP_07416211.2| conserved membrane protein [Mycobacterium tuberculosis SUMu001] gi|308369153|ref|ZP_07416742.2| conserved membrane protein [Mycobacterium tuberculosis SUMu002] gi|308371378|ref|ZP_07424750.2| conserved membrane protein [Mycobacterium tuberculosis SUMu003] 22 more sequence titles Length=245 Score = 483 bits (1244), Expect = 1e-134, Method: Compositional matrix adjust. Identities = 244/245 (99%), Positives = 245/245 (100%), Gaps = 0/245 (0%) Query 99 VVPIDLWNPDGVTVDLADAVYVADSGHKRLLKLPAGSNTPTTLPFTDTIGPGGVAVNSNR 158 +VPIDLWNPDGVTVDLADAVYVADSGHKRLLKLPAGSNTPTTLPFTDTIGPGGVAVNSNR Sbjct 1 MVPIDLWNPDGVTVDLADAVYVADSGHKRLLKLPAGSNTPTTLPFTDTIGPGGVAVNSNR 60 Query 159 DVYVIDEDSHHVLKLAAGIEPPVELPFGSLGDAHGLAVDRSDSVYVVDYDNAKVLKLPPG 218 DVYVIDEDSHHVLKLAAGIEPPVELPFGSLGDAHGLAVDRSDSVYVVDYDNAKVLKLPPG Sbjct 61 DVYVIDEDSHHVLKLAAGIEPPVELPFGSLGDAHGLAVDRSDSVYVVDYDNAKVLKLPPG 120 Query 219 ADTPTELPFVGLDHPYDVAVDGAGTVYVTDSGHNRVVALTAGSATPVHLPFADLSFPAGV 278 ADTPTELPFVGLDHPYDVAVDGAGTVYVTDSGHNRVVALTAGSATPVHLPFADLSFPAGV Sbjct 121 ADTPTELPFVGLDHPYDVAVDGAGTVYVTDSGHNRVVALTAGSATPVHLPFADLSFPAGV 180 Query 279 TVDRDDSVYVADLNNNRVLKLAAGSNAQSQLPFTGLFSPTDVAVDNDGAVYVIDFYNRML 338 TVDRDDSVYVADLNNNRVLKLAAGSNAQSQLPFTGLFSPTDVAVDNDGAVYVIDFYNRML Sbjct 181 TVDRDDSVYVADLNNNRVLKLAAGSNAQSQLPFTGLFSPTDVAVDNDGAVYVIDFYNRML 240 Query 339 KLPTA 343 KLPTA Sbjct 241 KLPTA 245 >gi|183984980|ref|YP_001853271.1| hypothetical protein MMAR_5012 [Mycobacterium marinum M] gi|183178306|gb|ACC43416.1| conserved hypothetical membrane protein [Mycobacterium marinum M] Length=312 Score = 320 bits (821), Expect = 1e-85, Method: Compositional matrix adjust. Identities = 172/296 (59%), Positives = 210/296 (71%), Gaps = 2/296 (0%) Query 46 PRNRRTLAITGAAVVVVVTLAAIGYLIFEPKISGSSTSRQAASPTTPSPPSQVVVPIDLW 105 PR R LAITG A+VVV LA GYLIF+P SG + ++ T P+Q+ + L Sbjct 10 PRKWRKLAITGGAIVVVAILAVTGYLIFKP--SGQAPVKRVDLSTAADQPAQIKLHFHLA 67 Query 106 NPDGVTVDLADAVYVADSGHKRLLKLPAGSNTPTTLPFTDTIGPGGVAVNSNRDVYVIDE 165 +PDGV +D D VYVADSG+ + KLPAGSNTP+ P + I PGGVAV+ + VYVID Sbjct 68 DPDGVALDSFDTVYVADSGNMLVQKLPAGSNTPSAFPISAKIVPGGVAVDRHNAVYVIDA 127 Query 166 DSHHVLKLAAGIEPPVELPFGSLGDAHGLAVDRSDSVYVVDYDNAKVLKLPPGADTPTEL 225 ++ VLK+ P+ELPF L D HGLA D +D+ YVVD+ N VLKLP G+ TP+EL Sbjct 128 AANRVLKVPPDSTIPIELPFTGLADPHGLAFDSADTCYVVDHVNNNVLKLPAGSSTPSEL 187 Query 226 PFVGLDHPYDVAVDGAGTVYVTDSGHNRVVALTAGSATPVHLPFADLSFPAGVTVDRDDS 285 F GLD PYDVA D A TVYVTDSGHNRVVAL AG+ PV LPF L+FPAGVTVD + Sbjct 188 GFTGLDRPYDVAADNADTVYVTDSGHNRVVALAAGATQPVDLPFTGLNFPAGVTVDLSGN 247 Query 286 VYVADLNNNRVLKLAAGSNAQSQLPFTGLFSPTDVAVDNDGAVYVIDFYNRMLKLP 341 VYVADLNNNRV+++ A ++ QS LPF LFSPTDVAVD+ G+VYVID+ +R+LKLP Sbjct 248 VYVADLNNNRVVRMDAATHEQSVLPFKDLFSPTDVAVDSQGSVYVIDYRDRVLKLP 303 >gi|183984979|ref|YP_001853270.1| hypothetical protein MMAR_5011 [Mycobacterium marinum M] gi|183178305|gb|ACC43415.1| conserved hypothetical secreted protein [Mycobacterium marinum M] Length=314 Score = 293 bits (751), Expect = 2e-77, Method: Compositional matrix adjust. Identities = 158/296 (54%), Positives = 200/296 (68%), Gaps = 0/296 (0%) Query 46 PRNRRTLAITGAAVVVVVTLAAIGYLIFEPKISGSSTSRQAASPTTPSPPSQVVVPIDLW 105 PR A+ G AV+VV LA YLI +P S ++ + + P+Q + + Sbjct 10 PRKWVRAAMAGGAVIVVAILAVSAYLIVKPSGKTPSDQLDRSAASAAAQPTQTTLHFNPS 69 Query 106 NPDGVTVDLADAVYVADSGHKRLLKLPAGSNTPTTLPFTDTIGPGGVAVNSNRDVYVIDE 165 P V VD D VYVADSG++ + KL GS+ P T+ + I PGGVAV+ + VYVIDE Sbjct 70 GPAAVAVDSLDTVYVADSGNRLVQKLTTGSSKPVTVRIGEPITPGGVAVDRHDVVYVIDE 129 Query 166 DSHHVLKLAAGIEPPVELPFGSLGDAHGLAVDRSDSVYVVDYDNAKVLKLPPGADTPTEL 225 ++ VLK+ AG PVELPF L D HGLA D D+ YVVD+ N VLKLP G+ TP+EL Sbjct 130 AANRVLKVPAGSTTPVELPFTGLADPHGLAFDSVDTCYVVDHVNNNVLKLPAGSTTPSEL 189 Query 226 PFVGLDHPYDVAVDGAGTVYVTDSGHNRVVALTAGSATPVHLPFADLSFPAGVTVDRDDS 285 F GLD PYDVA + GTVYVTDSGHNRV+AL G+ PV LPF L+FPAGV VD + + Sbjct 190 GFTGLDRPYDVAANNVGTVYVTDSGHNRVLALATGATQPVELPFTGLNFPAGVAVDLNGN 249 Query 286 VYVADLNNNRVLKLAAGSNAQSQLPFTGLFSPTDVAVDNDGAVYVIDFYNRMLKLP 341 +YVADLNNNRV++L A ++ Q+ LPF LFSPTDVAVDN G+VYVID+++R+LKLP Sbjct 250 IYVADLNNNRVVRLDAATHEQTVLPFDDLFSPTDVAVDNHGSVYVIDYHDRVLKLP 305 Score = 36.2 bits (82), Expect = 8.6, Method: Compositional matrix adjust. Identities = 22/43 (52%), Positives = 28/43 (66%), Gaps = 2/43 (4%) Query 96 SQVVVPID-LWNPDGVTVDLADAVYVADSGHKRLLKLPAGSNT 137 Q V+P D L++P V VD +VYV D H R+LKLPA SN+ Sbjct 269 EQTVLPFDDLFSPTDVAVDNHGSVYVIDY-HDRVLKLPAQSNS 310 >gi|240172359|ref|ZP_04751018.1| hypothetical protein MkanA1_23793 [Mycobacterium kansasii ATCC 12478] Length=273 Score = 273 bits (697), Expect = 4e-71, Method: Compositional matrix adjust. Identities = 145/258 (57%), Positives = 178/258 (69%), Gaps = 0/258 (0%) Query 85 QAASPTTPSPPSQVVVPIDLWNPDGVTVDLADAVYVADSGHKRLLKLPAGSNTPTTLPFT 144 QA T P P QVV+P ++ +PDGV VD VYVADS + R+LKLPAGS+ + LPFT Sbjct 15 QAGRSTVPPAPKQVVLPFEVGDPDGVAVDGKGDVYVADSSNNRVLKLPAGSDRQSELPFT 74 Query 145 DTIGPGGVAVNSNRDVYVIDEDSHHVLKLAAGIEPPVELPFGSLGDAHGLAVDRSDSVYV 204 P G+A++ + +Y++D ++ VLKL AG P ELPF L HG+AVDR+ +VYV Sbjct 75 GLNRPAGLALDVSGGIYLVDAYNNRVLKLPAGSPAPAELPFAGLSSPHGVAVDRNGTVYV 134 Query 205 VDYDNAKVLKLPPGADTPTELPFVGLDHPYDVAVDGAGTVYVTDSGHNRVVALTAGSATP 264 D N +VL+LP G++ P ELPF+GL HP AVD AG VYVTDS +NRV L AG TP Sbjct 135 ADSGNNRVLELPAGSNNPIELPFIGLRHPLGTAVDDAGAVYVTDSENNRVAKLAAGGTTP 194 Query 265 VHLPFADLSFPAGVTVDRDDSVYVADLNNNRVLKLAAGSNAQSQLPFTGLFSPTDVAVDN 324 V+LPF +L+FP GV VD + VYVADLNNNRVLKL AGSN S LPFT L P VAVDN Sbjct 195 VYLPFTELNFPHGVAVDHNGCVYVADLNNNRVLKLEAGSNTPSTLPFTDLNFPYGVAVDN 254 Query 325 DGAVYVIDFYNRMLKLPT 342 G VYV DF+ R++KL T Sbjct 255 AGNVYVTDFHKRVVKLST 272 >gi|183982552|ref|YP_001850843.1| hypothetical protein MMAR_2539 [Mycobacterium marinum M] gi|183175878|gb|ACC40988.1| conserved hypothetical protein [Mycobacterium marinum M] Length=341 Score = 216 bits (551), Expect = 3e-54, Method: Compositional matrix adjust. Identities = 126/234 (54%), Positives = 152/234 (65%), Gaps = 1/234 (0%) Query 109 GVTVDLADAVYVADSGHKRLLKLPAGSNTPTTLPFTDTIGPGGVAVNSNRDVYVIDEDSH 168 GV VD A VYVA G+ R+LKLPAGS+T LPFT P GVAV++ +VYV D + Sbjct 103 GVAVDTAGNVYVASGGNDRVLKLPAGSSTQVELPFTGLKSPMGVAVDTVGNVYVTDSFHN 162 Query 169 HVLKLAAGIEPPVELPFGSLGDAHGLAVDRSDSVYVVDYDNAKVLKLPPGADTPTELPFV 228 VLKL AG VELPF L G+AVD + +VYV D+ + ++LKLP G+ T ELPF Sbjct 163 RVLKLPAGSSTQVELPFTGLHRPGGVAVDAAGNVYVTDFVDNRMLKLPAGSSTQVELPFT 222 Query 229 GLDHPYDVAVDGAGTVYVTDSGHNRVVALTAGSATPVHLPFADLSFPAGVTVDRDDSVYV 288 GL P VAVD AG VYVT+ +NRV+ L AGS T V LPF L P V VD +VY Sbjct 223 GLHFPMGVAVDSAGNVYVTNDDNNRVLKLPAGSTTQVELPFTGLHHPVAVAVDTAGNVYA 282 Query 289 ADLNNNRVLKLAAGSNAQSQLPFTGLFSPTDVAVDNDGAVYVIDFYN-RMLKLP 341 AD +NNRVLKL AGS+ Q +LPFTGL P VAVD+ G VYV + N +L+LP Sbjct 283 ADHDNNRVLKLPAGSSTQVELPFTGLTGPMGVAVDSAGNVYVTNHDNDEVLELP 336 Score = 183 bits (465), Expect = 3e-44, Method: Compositional matrix adjust. Identities = 108/207 (53%), Positives = 133/207 (65%), Gaps = 1/207 (0%) Query 96 SQVVVPI-DLWNPDGVTVDLADAVYVADSGHKRLLKLPAGSNTPTTLPFTDTIGPGGVAV 154 +QV +P L +P GV VD VYV DS H R+LKLPAGS+T LPFT PGGVAV Sbjct 131 TQVELPFTGLKSPMGVAVDTVGNVYVTDSFHNRVLKLPAGSSTQVELPFTGLHRPGGVAV 190 Query 155 NSNRDVYVIDEDSHHVLKLAAGIEPPVELPFGSLGDAHGLAVDRSDSVYVVDYDNAKVLK 214 ++ +VYV D + +LKL AG VELPF L G+AVD + +VYV + DN +VLK Sbjct 191 DAAGNVYVTDFVDNRMLKLPAGSSTQVELPFTGLHFPMGVAVDSAGNVYVTNDDNNRVLK 250 Query 215 LPPGADTPTELPFVGLDHPYDVAVDGAGTVYVTDSGHNRVVALTAGSATPVHLPFADLSF 274 LP G+ T ELPF GL HP VAVD AG VY D +NRV+ L AGS+T V LPF L+ Sbjct 251 LPAGSTTQVELPFTGLHHPVAVAVDTAGNVYAADHDNNRVLKLPAGSSTQVELPFTGLTG 310 Query 275 PAGVTVDRDDSVYVADLNNNRVLKLAA 301 P GV VD +VYV + +N+ VL+L A Sbjct 311 PMGVAVDSAGNVYVTNHDNDEVLELPA 337 Score = 181 bits (459), Expect = 2e-43, Method: Compositional matrix adjust. Identities = 109/203 (54%), Positives = 127/203 (63%), Gaps = 2/203 (0%) Query 141 LPFTDT-IGPGGVAVNSNRDVYVIDEDSHHVLKLAAGIEPPVELPFGSLGDAHGLAVDRS 199 LPF + GGVAV++ +VYV + VLKL AG VELPF L G+AVD Sbjct 92 LPFIGLYVHTGGVAVDTAGNVYVASGGNDRVLKLPAGSSTQVELPFTGLKSPMGVAVDTV 151 Query 200 DSVYVVDYDNAKVLKLPPGADTPTELPFVGLDHPYDVAVDGAGTVYVTDSGHNRVVALTA 259 +VYV D + +VLKLP G+ T ELPF GL P VAVD AG VYVTD NR++ L A Sbjct 152 GNVYVTDSFHNRVLKLPAGSSTQVELPFTGLHRPGGVAVDAAGNVYVTDFVDNRMLKLPA 211 Query 260 GSATPVHLPFADLSFPAGVTVDRDDSVYVADLNNNRVLKLAAGSNAQSQLPFTGLFSPTD 319 GS+T V LPF L FP GV VD +VYV + +NNRVLKL AGS Q +LPFTGL P Sbjct 212 GSSTQVELPFTGLHFPMGVAVDSAGNVYVTNDDNNRVLKLPAGSTTQVELPFTGLHHPVA 271 Query 320 VAVDNDGAVYVIDF-YNRMLKLP 341 VAVD G VY D NR+LKLP Sbjct 272 VAVDTAGNVYAADHDNNRVLKLP 294 >gi|183983388|ref|YP_001851679.1| transmembrane serine/threonine-protein kinase D [Mycobacterium marinum M] gi|183176714|gb|ACC41824.1| transmembrane serine/threonine-protein kinase D [Mycobacterium marinum M] Length=622 Score = 207 bits (528), Expect = 2e-51, Method: Compositional matrix adjust. Identities = 117/245 (48%), Positives = 152/245 (63%), Gaps = 1/245 (0%) Query 97 QVVVPI-DLWNPDGVTVDLADAVYVADSGHKRLLKLPAGSNTPTTLPFTDTIGPGGVAVN 155 QV +P L +P G++VD VYV D+ H R+L L AGS TP LPF P GV + Sbjct 375 QVTLPFTGLRDPQGLSVDYGGTVYVGDTLHNRILALSAGSTTPAVLPFEGLSYPTGVTAD 434 Query 156 SNRDVYVIDEDSHHVLKLAAGIEPPVELPFGSLGDAHGLAVDRSDSVYVVDYDNAKVLKL 215 ++ VYV D + VL L AG + LPF LG+ GL VD S +VYV D +V+ L Sbjct 435 NSGTVYVNDAGNRRVLVLRAGTSTQITLPFTDLGNPTGLTVDSSRTVYVTDTAKNRVVAL 494 Query 216 PPGADTPTELPFVGLDHPYDVAVDGAGTVYVTDSGHNRVVALTAGSATPVHLPFADLSFP 275 P G++ T+LPF GL+ P + V+G+GTVYV D G+NRV+AL AGS + LPF L+ P Sbjct 495 PAGSNMQTQLPFTGLNSPTGLVVNGSGTVYVADGGNNRVLALPAGSKRQIALPFTGLNQP 554 Query 276 AGVTVDRDDSVYVADLNNNRVLKLAAGSNAQSQLPFTGLFSPTDVAVDNDGAVYVIDFYN 335 GVT+D + +VYV D NNR LKL AGS Q +LPFTGL P +AVDN G VYV + Sbjct 555 GGVTLDNEGAVYVTDSGNNRTLKLPAGSTTQIELPFTGLDFPWGLAVDNMGTVYVGSRSS 614 Query 336 RMLKL 340 +++ L Sbjct 615 QIVAL 619 Score = 164 bits (414), Expect = 3e-38, Method: Compositional matrix adjust. Identities = 100/203 (50%), Positives = 119/203 (59%), Gaps = 1/203 (0%) Query 140 TLPFTDTIGPGGVAVNSNRDVYVIDEDSHHVLKLAAGIEPPVELPFGSLGDAHGLAVDRS 199 TLPFT P G++V+ VYV D + +L L+AG P LPF L G+ D S Sbjct 377 TLPFTGLRDPQGLSVDYGGTVYVGDTLHNRILALSAGSTTPAVLPFEGLSYPTGVTADNS 436 Query 200 DSVYVVDYDNAKVLKLPPGADTPTELPFVGLDHPYDVAVDGAGTVYVTDSGHNRVVALTA 259 +VYV D N +VL L G T LPF L +P + VD + TVYVTD+ NRVVAL A Sbjct 437 GTVYVNDAGNRRVLVLRAGTSTQITLPFTDLGNPTGLTVDSSRTVYVTDTAKNRVVALPA 496 Query 260 GSATPVHLPFADLSFPAGVTVDRDDSVYVADLNNNRVLKLAAGSNAQSQLPFTGLFSPTD 319 GS LPF L+ P G+ V+ +VYVAD NNRVL L AGS Q LPFTGL P Sbjct 497 GSNMQTQLPFTGLNSPTGLVVNGSGTVYVADGGNNRVLALPAGSKRQIALPFTGLNQPGG 556 Query 320 VAVDNDGAVYVIDF-YNRMLKLP 341 V +DN+GAVYV D NR LKLP Sbjct 557 VTLDNEGAVYVTDSGNNRTLKLP 579 Score = 159 bits (403), Expect = 5e-37, Method: Compositional matrix adjust. Identities = 96/212 (46%), Positives = 126/212 (60%), Gaps = 6/212 (2%) Query 86 AASPTTPSPPSQVVVPID-LWNPDGVTVDLADAVYVADSGHKRLLKLPAGSNTPTTLPFT 144 +A TTP+ V+P + L P GVT D + VYV D+G++R+L L AG++T TLPFT Sbjct 411 SAGSTTPA-----VLPFEGLSYPTGVTADNSGTVYVNDAGNRRVLVLRAGTSTQITLPFT 465 Query 145 DTIGPGGVAVNSNRDVYVIDEDSHHVLKLAAGIEPPVELPFGSLGDAHGLAVDRSDSVYV 204 D P G+ V+S+R VYV D + V+ L AG +LPF L GL V+ S +VYV Sbjct 466 DLGNPTGLTVDSSRTVYVTDTAKNRVVALPAGSNMQTQLPFTGLNSPTGLVVNGSGTVYV 525 Query 205 VDYDNAKVLKLPPGADTPTELPFVGLDHPYDVAVDGAGTVYVTDSGHNRVVALTAGSATP 264 D N +VL LP G+ LPF GL+ P V +D G VYVTDSG+NR + L AGS T Sbjct 526 ADGGNNRVLALPAGSKRQIALPFTGLNQPGGVTLDNEGAVYVTDSGNNRTLKLPAGSTTQ 585 Query 265 VHLPFADLSFPAGVTVDRDDSVYVADLNNNRV 296 + LPF L FP G+ VD +VYV ++ V Sbjct 586 IELPFTGLDFPWGLAVDNMGTVYVGSRSSQIV 617 >gi|333992173|ref|YP_004524787.1| serine/threonine-protein kinase [Mycobacterium sp. JDM601] gi|333488141|gb|AEF37533.1| transmembrane serine/threonine-protein kinase D PknD [Mycobacterium sp. JDM601] Length=660 Score = 204 bits (518), Expect = 2e-50, Method: Compositional matrix adjust. Identities = 128/268 (48%), Positives = 166/268 (62%), Gaps = 7/268 (2%) Query 79 GSSTSRQAASPTTPSPPSQVVVPID----LWNPDGVTVDLADAVYVAD-SGHKRLLKLPA 133 G + SR++ S T S Q VVP++ +P G+ +D D +Y+ + S + R+LKL Sbjct 390 GYALSRESGSTTGVSADGQSVVPLEGLSFRLSPGGLALDGDDNLYITNQSMYGRVLKLVP 449 Query 134 GSNTPTTLPFTDTIGPGGVAVNSNRDVYVIDEDSHHVLKLAAGIEPPVELPFGSLGDAHG 193 GS+ P LPFT P GVAV ++ VYV D + + V+KLA ELPF L G Sbjct 450 GSSNPEVLPFTGLYEPQGVAVAADGSVYVSDFN-NRVVKLAPDTGEQTELPFAGLNYPEG 508 Query 194 LAVDRSDSVYVVDYDNAKVLKLPPGADTPTELPFVGLDHPYDVAVDGAGTVYVTDSGHNR 253 + VD SVYV D N +VLKLP GA LPF GL HP DVAVD G VYVTD+ ++R Sbjct 509 VEVDAQGSVYVADRGNNRVLKLPAGAGAQVVLPFTGLHHPDDVAVDSNGNVYVTDTDNDR 568 Query 254 VVALTAGSATPVHLPFADLSFPAGVTVDRDDSVYVADLNNNRVLKLAAGSNAQSQLPFTG 313 VV L+AGS T LPF LS P GV+VDR D+VYV + N++V+KL +N Q++LPF+G Sbjct 569 VVRLSAGSNTQTDLPFTGLSSPWGVSVDRADNVYVTNHENHKVMKLDPVTNNQTKLPFSG 628 Query 314 LFSPTDVAVDNDGAVYVIDF-YNRMLKL 340 L +P V VD DGAVYV D NR++KL Sbjct 629 LNTPLQVVVDADGAVYVADRGNNRVVKL 656 Score = 149 bits (375), Expect = 9e-34, Method: Compositional matrix adjust. Identities = 83/171 (49%), Positives = 108/171 (64%), Gaps = 1/171 (0%) Query 92 PSPPSQVVVPIDLWN-PDGVTVDLADAVYVADSGHKRLLKLPAGSNTPTTLPFTDTIGPG 150 P Q +P N P+GV VD +VYVAD G+ R+LKLPAG+ LPFT P Sbjct 490 PDTGEQTELPFAGLNYPEGVEVDAQGSVYVADRGNNRVLKLPAGAGAQVVLPFTGLHHPD 549 Query 151 GVAVNSNRDVYVIDEDSHHVLKLAAGIEPPVELPFGSLGDAHGLAVDRSDSVYVVDYDNA 210 VAV+SN +VYV D D+ V++L+AG +LPF L G++VDR+D+VYV +++N Sbjct 550 DVAVDSNGNVYVTDTDNDRVVRLSAGSNTQTDLPFTGLSSPWGVSVDRADNVYVTNHENH 609 Query 211 KVLKLPPGADTPTELPFVGLDHPYDVAVDGAGTVYVTDSGHNRVVALTAGS 261 KV+KL P + T+LPF GL+ P V VD G VYV D G+NRVV L AGS Sbjct 610 KVMKLDPVTNNQTKLPFSGLNTPLQVVVDADGAVYVADRGNNRVVKLAAGS 660 >gi|298524423|ref|ZP_07011832.1| transmembrane serine/threonine-protein kinase d pkndb [Mycobacterium tuberculosis 94_M4241A] gi|298494217|gb|EFI29511.1| transmembrane serine/threonine-protein kinase d pkndb [Mycobacterium tuberculosis 94_M4241A] Length=330 Score = 203 bits (516), Expect = 4e-50, Method: Compositional matrix adjust. Identities = 135/296 (46%), Positives = 171/296 (58%), Gaps = 14/296 (4%) Query 49 RRTLAITGAAVVVVVTL-AAIGYLIFEPKISGSSTSRQAASPTTPSPPSQVVVPIDL-WN 106 R+ A+ GAA +V+V + AA GYL+ P S + S Q P T ID + Sbjct 43 RKVWAVVGAAAIVLVAIVAAAGYLVLRPSWSPTQASGQTVLPFTG---------IDFRLS 93 Query 107 PDGVTVDLADAVYVADSG-HKRLLKLPAGSNTPTTLPFTDTIGPGGVAVNSNRDVYVIDE 165 P GV VD A VYV G + R++KL GS T LPF P G+AV+ VYV D Sbjct 94 PSGVAVDSAGNVYVTSEGMYGRVVKLATGSTGTTVLPFNGLYQPQGLAVDGAGTVYVTDF 153 Query 166 DSHHVLKLAAGIEPPVELPFGSLGDAHGLAVDRSDSVYVVDYDNAKVLKLPPGADTPTEL 225 + + V+ LAAG LPF L GLAVD +VYV D N +V+KL G+ T T L Sbjct 154 N-NRVVTLAAGSNNQTVLPFDGLNYPEGLAVDTQGAVYVADRGNNRVVKLAAGSKTQTVL 212 Query 226 PFVGLDHPYDVAVDGAGTVYVTDSGHNRVVALTAGSATPVHLPFADLSFPAGVTVDRDDS 285 PF GL+ P VAVD +G VYVTD+ +NRVV L A S V LPF D++ P G+ VD + Sbjct 213 PFTGLNDPDGVAVDNSGNVYVTDTDNNRVVKLEAESNNQVVLPFTDITAPWGIAVDEAGT 272 Query 286 VYVADLNNNRVLKLAAGSNAQSQLPFTGLFSPTDVAVDNDGAVYVIDFYN-RMLKL 340 VYV + N N+V+KL AGS + LPFTGL +P VAVD+D VYV D N R++KL Sbjct 273 VYVTEHNTNQVVKLLAGSTTSTVLPFTGLNTPLAVAVDSDRTVYVADRGNDRVVKL 328 >gi|31792118|ref|NP_854611.1| serine/threonine protein kinase D [Mycobacterium bovis AF2122/97] gi|121636854|ref|YP_977077.1| transmembrane serine/threonine-protein kinase D pknDb [Mycobacterium bovis BCG str. Pasteur 1173P2] gi|224989325|ref|YP_002644012.1| hypothetical protein JTY_0953 [Mycobacterium bovis BCG str. Tokyo 172] gi|31617706|emb|CAD93815.1| TRANSMEMBRANE SERINE/THREONINE-PROTEIN KINASE D PKNDb [SECOND PART](PROTEIN KINASE D) (STPK D) [Mycobacterium bovis AF2122/97] gi|121492501|emb|CAL70969.1| transmembrane serine/threonine-protein kinase D pknDb [second part] [Mycobacterium bovis BCG str. Pasteur 1173P2] gi|224772438|dbj|BAH25244.1| pknDb [Mycobacterium bovis BCG str. Tokyo 172] gi|341600870|emb|CCC63541.1| transmembrane serine/threonine-protein kinase D pknDb [second part] [Mycobacterium bovis BCG str. Moreau RDJ] Length=369 Score = 203 bits (516), Expect = 4e-50, Method: Compositional matrix adjust. Identities = 135/296 (46%), Positives = 171/296 (58%), Gaps = 14/296 (4%) Query 49 RRTLAITGAAVVVVVTL-AAIGYLIFEPKISGSSTSRQAASPTTPSPPSQVVVPIDL-WN 106 R+ A+ GAA +V+V + AA GYL+ P S + S Q P T ID + Sbjct 82 RKVWAVVGAAAIVLVAIVAAAGYLVLRPSWSPTQASGQTVLPFTG---------IDFRLS 132 Query 107 PDGVTVDLADAVYVADSG-HKRLLKLPAGSNTPTTLPFTDTIGPGGVAVNSNRDVYVIDE 165 P GV VD A VYV G + R++KL GS T LPF P G+AV+ VYV D Sbjct 133 PSGVAVDSAGNVYVTSEGMYGRVVKLATGSTGTTVLPFNGLYQPQGLAVDGAGTVYVTDF 192 Query 166 DSHHVLKLAAGIEPPVELPFGSLGDAHGLAVDRSDSVYVVDYDNAKVLKLPPGADTPTEL 225 + + V+ LAAG LPF L GLAVD +VYV D N +V+KL G+ T T L Sbjct 193 N-NRVVTLAAGSNNQTVLPFDGLNYPEGLAVDTQGAVYVADRGNNRVVKLAAGSKTQTVL 251 Query 226 PFVGLDHPYDVAVDGAGTVYVTDSGHNRVVALTAGSATPVHLPFADLSFPAGVTVDRDDS 285 PF GL+ P VAVD +G VYVTD+ +NRVV L A S V LPF D++ P G+ VD + Sbjct 252 PFTGLNDPDGVAVDNSGNVYVTDTDNNRVVKLEAESNNQVVLPFTDITAPWGIAVDEAGT 311 Query 286 VYVADLNNNRVLKLAAGSNAQSQLPFTGLFSPTDVAVDNDGAVYVIDFYN-RMLKL 340 VYV + N N+V+KL AGS + LPFTGL +P VAVD+D VYV D N R++KL Sbjct 312 VYVTEHNTNQVVKLLAGSTTSTVLPFTGLNTPLAVAVDSDRTVYVADRGNDRVVKL 367 >gi|339630994|ref|YP_004722636.1| Ser/Thr protein kinase D [Mycobacterium africanum GM041182] gi|339330350|emb|CCC26012.1| transmembrane serine/threonine-protein kinase D PKND (protein kinase D) [Mycobacterium africanum GM041182] Length=664 Score = 202 bits (515), Expect = 4e-50, Method: Compositional matrix adjust. Identities = 135/297 (46%), Positives = 171/297 (58%), Gaps = 14/297 (4%) Query 48 NRRTLAITGAAVVVVVTL-AAIGYLIFEPKISGSSTSRQAASPTTPSPPSQVVVPIDL-W 105 R+ A+ GAA +V+V + AA GYL+ P S + S Q P T ID Sbjct 376 KRKVWAVVGAAAIVLVAIVAAAGYLVLRPSWSPTQASGQTVLPFTG---------IDFRL 426 Query 106 NPDGVTVDLADAVYVADSG-HKRLLKLPAGSNTPTTLPFTDTIGPGGVAVNSNRDVYVID 164 +P GV VD A VYV G + R++KL GS T LPF P G+AV+ VYV D Sbjct 427 SPSGVAVDSAGNVYVTSEGMYGRVVKLATGSTGTTVLPFNGLYQPQGLAVDGAGTVYVTD 486 Query 165 EDSHHVLKLAAGIEPPVELPFGSLGDAHGLAVDRSDSVYVVDYDNAKVLKLPPGADTPTE 224 + + V+ LAAG LPF L GLAVD +VYV D N +V+KL G+ T T Sbjct 487 FN-NRVVTLAAGSNNQTVLPFDGLNYPEGLAVDTQGAVYVADRGNNRVVKLAAGSKTQTV 545 Query 225 LPFVGLDHPYDVAVDGAGTVYVTDSGHNRVVALTAGSATPVHLPFADLSFPAGVTVDRDD 284 LPF GL+ P VAVD +G VYVTD+ +NRVV L A S V LPF D++ P G+ VD Sbjct 546 LPFTGLNDPDGVAVDNSGNVYVTDTDNNRVVKLEAESNNQVVLPFTDITAPWGIAVDEAG 605 Query 285 SVYVADLNNNRVLKLAAGSNAQSQLPFTGLFSPTDVAVDNDGAVYVIDFYN-RMLKL 340 +VYV + N N+V+KL AGS + LPFTGL +P VAVD+D VYV D N R++KL Sbjct 606 TVYVTEHNTNQVVKLLAGSTTSTVLPFTGLNTPLAVAVDSDRTVYVADRGNDRVVKL 662 >gi|289446501|ref|ZP_06436245.1| transmembrane serine/threonine-protein kinase D pknD [Mycobacterium tuberculosis CPHL_A] gi|289419459|gb|EFD16660.1| transmembrane serine/threonine-protein kinase D pknD [Mycobacterium tuberculosis CPHL_A] Length=664 Score = 202 bits (515), Expect = 5e-50, Method: Compositional matrix adjust. Identities = 135/297 (46%), Positives = 171/297 (58%), Gaps = 14/297 (4%) Query 48 NRRTLAITGAAVVVVVTL-AAIGYLIFEPKISGSSTSRQAASPTTPSPPSQVVVPIDL-W 105 R+ A+ GAA +V+V + AA GYL+ P S + S Q P T ID Sbjct 376 KRKVWAVVGAAAIVLVAIVAAAGYLVLRPSWSPTQASGQTVLPFTG---------IDFRL 426 Query 106 NPDGVTVDLADAVYVADSG-HKRLLKLPAGSNTPTTLPFTDTIGPGGVAVNSNRDVYVID 164 +P GV VD A VYV G + R++KL GS T LPF P G+AV+ VYV D Sbjct 427 SPSGVAVDSAGNVYVTSEGMYGRVVKLATGSTGTTVLPFNGLYQPQGLAVDGAGTVYVTD 486 Query 165 EDSHHVLKLAAGIEPPVELPFGSLGDAHGLAVDRSDSVYVVDYDNAKVLKLPPGADTPTE 224 + + V+ LAAG LPF L GLAVD +VYV D N +V+KL G+ T T Sbjct 487 FN-NRVVTLAAGSNNQTVLPFDGLNYPEGLAVDTQGAVYVADRGNNRVVKLAAGSKTQTV 545 Query 225 LPFVGLDHPYDVAVDGAGTVYVTDSGHNRVVALTAGSATPVHLPFADLSFPAGVTVDRDD 284 LPF GL+ P VAVD +G VYVTD+ +NRVV L A S V LPF D++ P G+ VD Sbjct 546 LPFTGLNDPDGVAVDNSGNVYVTDTDNNRVVKLEAESNNQVVLPFTDITAPWGIAVDEAG 605 Query 285 SVYVADLNNNRVLKLAAGSNAQSQLPFTGLFSPTDVAVDNDGAVYVIDFYN-RMLKL 340 +VYV + N N+V+KL AGS + LPFTGL +P VAVD+D VYV D N R++KL Sbjct 606 TVYVTEHNTNQVVKLLAGSTTSTVLPFTGLNTPLAVAVDSDRTVYVADRGNDRVVKL 662 >gi|254549912|ref|ZP_05140359.1| transmembrane serine/threonine-protein kinase D pknD [Mycobacterium tuberculosis '98-R604 INH-RIF-EM'] Length=624 Score = 202 bits (515), Expect = 5e-50, Method: Compositional matrix adjust. Identities = 135/297 (46%), Positives = 171/297 (58%), Gaps = 14/297 (4%) Query 48 NRRTLAITGAAVVVVVTL-AAIGYLIFEPKISGSSTSRQAASPTTPSPPSQVVVPIDL-W 105 R+ A+ GAA +V+V + AA GYL+ P S + S Q P T ID Sbjct 336 KRKVWAVVGAAAIVLVAIVAAAGYLVLRPSWSPTQASGQTVLPFTG---------IDFRL 386 Query 106 NPDGVTVDLADAVYVADSG-HKRLLKLPAGSNTPTTLPFTDTIGPGGVAVNSNRDVYVID 164 +P GV VD A VYV G + R++KL GS T LPF P G+AV+ VYV D Sbjct 387 SPSGVAVDSAGNVYVTSEGMYGRVVKLATGSTGTTVLPFNGLYQPQGLAVDGAGTVYVTD 446 Query 165 EDSHHVLKLAAGIEPPVELPFGSLGDAHGLAVDRSDSVYVVDYDNAKVLKLPPGADTPTE 224 + + V+ LAAG LPF L GLAVD +VYV D N +V+KL G+ T T Sbjct 447 FN-NRVVTLAAGSNNQTVLPFDGLNYPEGLAVDTQGAVYVADRGNNRVVKLAAGSKTQTV 505 Query 225 LPFVGLDHPYDVAVDGAGTVYVTDSGHNRVVALTAGSATPVHLPFADLSFPAGVTVDRDD 284 LPF GL+ P VAVD +G VYVTD+ +NRVV L A S V LPF D++ P G+ VD Sbjct 506 LPFTGLNDPDGVAVDNSGNVYVTDTDNNRVVKLEAESNNQVVLPFTDITAPWGIAVDEAG 565 Query 285 SVYVADLNNNRVLKLAAGSNAQSQLPFTGLFSPTDVAVDNDGAVYVIDFYN-RMLKL 340 +VYV + N N+V+KL AGS + LPFTGL +P VAVD+D VYV D N R++KL Sbjct 566 TVYVTEHNTNQVVKLLAGSTTSTVLPFTGLNTPLAVAVDSDRTVYVADRGNDRVVKL 622 >gi|15608071|ref|NP_215446.1| transmembrane serine/threonine-protein kinase D PKND (protein kinase D) (STPK D) [Mycobacterium tuberculosis H37Rv] gi|15840354|ref|NP_335391.1| serine/threonine protein kinase [Mycobacterium tuberculosis CDC1551] gi|148660710|ref|YP_001282233.1| serine/threonine protein kinase [Mycobacterium tuberculosis H37Ra] 62 more sequence titles Length=664 Score = 202 bits (515), Expect = 5e-50, Method: Compositional matrix adjust. Identities = 135/297 (46%), Positives = 171/297 (58%), Gaps = 14/297 (4%) Query 48 NRRTLAITGAAVVVVVTL-AAIGYLIFEPKISGSSTSRQAASPTTPSPPSQVVVPIDL-W 105 R+ A+ GAA +V+V + AA GYL+ P S + S Q P T ID Sbjct 376 KRKVWAVVGAAAIVLVAIVAAAGYLVLRPSWSPTQASGQTVLPFTG---------IDFRL 426 Query 106 NPDGVTVDLADAVYVADSG-HKRLLKLPAGSNTPTTLPFTDTIGPGGVAVNSNRDVYVID 164 +P GV VD A VYV G + R++KL GS T LPF P G+AV+ VYV D Sbjct 427 SPSGVAVDSAGNVYVTSEGMYGRVVKLATGSTGTTVLPFNGLYQPQGLAVDGAGTVYVTD 486 Query 165 EDSHHVLKLAAGIEPPVELPFGSLGDAHGLAVDRSDSVYVVDYDNAKVLKLPPGADTPTE 224 + + V+ LAAG LPF L GLAVD +VYV D N +V+KL G+ T T Sbjct 487 FN-NRVVTLAAGSNNQTVLPFDGLNYPEGLAVDTQGAVYVADRGNNRVVKLAAGSKTQTV 545 Query 225 LPFVGLDHPYDVAVDGAGTVYVTDSGHNRVVALTAGSATPVHLPFADLSFPAGVTVDRDD 284 LPF GL+ P VAVD +G VYVTD+ +NRVV L A S V LPF D++ P G+ VD Sbjct 546 LPFTGLNDPDGVAVDNSGNVYVTDTDNNRVVKLEAESNNQVVLPFTDITAPWGIAVDEAG 605 Query 285 SVYVADLNNNRVLKLAAGSNAQSQLPFTGLFSPTDVAVDNDGAVYVIDFYN-RMLKL 340 +VYV + N N+V+KL AGS + LPFTGL +P VAVD+D VYV D N R++KL Sbjct 606 TVYVTEHNTNQVVKLLAGSTTSTVLPFTGLNTPLAVAVDSDRTVYVADRGNDRVVKL 662 >gi|289442346|ref|ZP_06432090.1| transmembrane serine/threonine-protein kinase D pknD [Mycobacterium tuberculosis T46] gi|289415265|gb|EFD12505.1| transmembrane serine/threonine-protein kinase D pknD [Mycobacterium tuberculosis T46] Length=664 Score = 202 bits (513), Expect = 8e-50, Method: Compositional matrix adjust. Identities = 135/297 (46%), Positives = 171/297 (58%), Gaps = 14/297 (4%) Query 48 NRRTLAITGAAVVVVVTL-AAIGYLIFEPKISGSSTSRQAASPTTPSPPSQVVVPIDL-W 105 R+ A+ GAA +V+V + AA GYL+ P S + S Q P T ID Sbjct 376 KRKVWAVVGAAAIVLVAIVAAAGYLVLRPSWSPTQASGQTVLPFTG---------IDFRL 426 Query 106 NPDGVTVDLADAVYVADSG-HKRLLKLPAGSNTPTTLPFTDTIGPGGVAVNSNRDVYVID 164 +P GV VD A VYV G + R++KL GS T LPF P G+AV+ VYV D Sbjct 427 SPSGVAVDSAGNVYVTSEGMYGRVVKLATGSTGTTVLPFNGLYQPPGLAVDGAGTVYVTD 486 Query 165 EDSHHVLKLAAGIEPPVELPFGSLGDAHGLAVDRSDSVYVVDYDNAKVLKLPPGADTPTE 224 + + V+ LAAG LPF L GLAVD +VYV D N +V+KL G+ T T Sbjct 487 FN-NRVVTLAAGSNNQTVLPFDGLNYPEGLAVDTQGAVYVADRGNNRVVKLAAGSKTQTV 545 Query 225 LPFVGLDHPYDVAVDGAGTVYVTDSGHNRVVALTAGSATPVHLPFADLSFPAGVTVDRDD 284 LPF GL+ P VAVD +G VYVTD+ +NRVV L A S V LPF D++ P G+ VD Sbjct 546 LPFTGLNDPDGVAVDNSGNVYVTDTDNNRVVKLEAESNNQVVLPFTDITAPWGIAVDEAG 605 Query 285 SVYVADLNNNRVLKLAAGSNAQSQLPFTGLFSPTDVAVDNDGAVYVIDFYN-RMLKL 340 +VYV + N N+V+KL AGS + LPFTGL +P VAVD+D VYV D N R++KL Sbjct 606 TVYVTEHNTNQVVKLLAGSTTSTVLPFTGLNTPLAVAVDSDRTVYVADRGNDRVVKL 662 >gi|183984546|ref|YP_001852837.1| transmembrane serine/threonine-protein kinase D PknD [Mycobacterium marinum M] gi|183177872|gb|ACC42982.1| transmembrane serine/threonine-protein kinase D PknD [Mycobacterium marinum M] Length=698 Score = 197 bits (502), Expect = 2e-48, Method: Compositional matrix adjust. Identities = 120/254 (48%), Positives = 159/254 (63%), Gaps = 7/254 (2%) Query 93 SPPSQVVVPIDLWN----PDGVTVDLADAVYVAD-SGHKRLLKLPAGSNTPTTLPFTDTI 147 P QVV+P N P GV VD VYV + + + R++ LPAGS+TPT PF Sbjct 442 EPRGQVVLPFTGLNFRFAPGGVAVDANGTVYVTNQTMYGRVVALPAGSSTPTVKPFNGLY 501 Query 148 GPGGVAVNSNRDVYVIDEDSHHVLKLAAGIEPPVELPFGSLGDAHGLAVDRSDSVYVVDY 207 P GVAV+++ +YV D + + V+ LAAG VELPF L G+AVD +VYV D Sbjct 502 EPQGVAVDTSGKIYVTDFN-NRVVALAAGSNNQVELPFNGLNYPEGIAVDAQGNVYVADR 560 Query 208 DNAKVLKLPPGADTPTELPFVGLDHPYDVAVDGAGTVYVTDSGHNRVVALTAGSATPVHL 267 N +V+K+P G+ + LPF GL +P VAVD G VYVTD+ +NRV+ L AG++ L Sbjct 561 GNNRVVKMPAGSTSQVVLPFNGLKNPDGVAVDSDGNVYVTDTDNNRVLQLDAGTSNQSVL 620 Query 268 PFADLSFPAGVTVDRDDSVYVADLNNNRVLKLAAGSNAQSQLPFTGLFSPTDVAVDNDGA 327 PF++L+ P G+TVD +VYV + +NN V KLAAG+ ++LPFTGL +P VAVD G Sbjct 621 PFSNLTAPWGITVDSAGNVYVTEHDNNAVAKLAAGATTSTELPFTGLNTPLSVAVDKKGN 680 Query 328 VYVIDFYN-RMLKL 340 VYV D N R+LKL Sbjct 681 VYVADRGNGRVLKL 694 Score = 159 bits (402), Expect = 6e-37, Method: Compositional matrix adjust. Identities = 97/221 (44%), Positives = 127/221 (58%), Gaps = 4/221 (1%) Query 84 RQAASPTTPSPPSQVVVPID-LWNPDGVTVDLADAVYVADSGHKRLLKLPAGSNTPTTLP 142 R A P S P+ V P + L+ P GV VD + +YV D + R++ L AGSN LP Sbjct 481 RVVALPAGSSTPT--VKPFNGLYEPQGVAVDTSGKIYVTDF-NNRVVALAAGSNNQVELP 537 Query 143 FTDTIGPGGVAVNSNRDVYVIDEDSHHVLKLAAGIEPPVELPFGSLGDAHGLAVDRSDSV 202 F P G+AV++ +VYV D ++ V+K+ AG V LPF L + G+AVD +V Sbjct 538 FNGLNYPEGIAVDAQGNVYVADRGNNRVVKMPAGSTSQVVLPFNGLKNPDGVAVDSDGNV 597 Query 203 YVVDYDNAKVLKLPPGADTPTELPFVGLDHPYDVAVDGAGTVYVTDSGHNRVVALTAGSA 262 YV D DN +VL+L G + LPF L P+ + VD AG VYVT+ +N V L AG+ Sbjct 598 YVTDTDNNRVLQLDAGTSNQSVLPFSNLTAPWGITVDSAGNVYVTEHDNNAVAKLAAGAT 657 Query 263 TPVHLPFADLSFPAGVTVDRDDSVYVADLNNNRVLKLAAGS 303 T LPF L+ P V VD+ +VYVAD N RVLKLA GS Sbjct 658 TSTELPFTGLNTPLSVAVDKKGNVYVADRGNGRVLKLAQGS 698 >gi|240170121|ref|ZP_04748780.1| transmembrane serine/threonine-protein kinase D [Mycobacterium kansasii ATCC 12478] Length=643 Score = 194 bits (492), Expect = 2e-47, Method: Compositional matrix adjust. Identities = 128/288 (45%), Positives = 168/288 (59%), Gaps = 17/288 (5%) Query 45 WPRNRRTLAITGAAVVVV-VTLAAIGYLIFEPKISGSSTSRQAASPTTPSPPSQVVVPID 103 W R R+ + IT AA++ V VT+AA ++ +S T Q QVV+P Sbjct 358 WWR-RKAVVITAAALLTVAVTVAA---MVTVSTLSPERTEFQ-----------QVVLPFT 402 Query 104 -LWNPDGVTVDLADAVYVADSGHKRLLKLPAGSNTPTTLPFTDTIGPGGVAVNSNRDVYV 162 L +P G++VD VYV D+ H R+L L AGS TP LPF P GV +++ VYV Sbjct 403 GLRDPQGLSVDSGGTVYVGDTLHNRILALFAGSTTPVVLPFDGLSYPTGVTADNSGTVYV 462 Query 163 IDEDSHHVLKLAAGIEPPVELPFGSLGDAHGLAVDRSDSVYVVDYDNAKVLKLPPGADTP 222 D + V+ L AG + V LPF L + GL+VD S +VYV D +V+ L G++T Sbjct 463 NDAGNRRVVVLPAGSKTQVTLPFTDLSNPTGLSVDSSRTVYVTDTAKNRVVGLYAGSNTQ 522 Query 223 TELPFVGLDHPYDVAVDGAGTVYVTDSGHNRVVALTAGSATPVHLPFADLSFPAGVTVDR 282 ELPF GL P + VD +GTV V D G+NRV+AL AG+ T V LPF L P GVTVD Sbjct 523 FELPFTGLSDPTGLVVDSSGTVIVADGGNNRVLALPAGAQTQVTLPFTGLKQPGGVTVDS 582 Query 283 DDSVYVADLNNNRVLKLAAGSNAQSQLPFTGLFSPTDVAVDNDGAVYV 330 + +VYV + N R+LKL GS+ Q +L FTGL +P +AVDN G VYV Sbjct 583 EGAVYVTNKGNGRILKLPPGSSTQVELHFTGLDNPWGLAVDNMGTVYV 630 Score = 161 bits (408), Expect = 1e-37, Method: Compositional matrix adjust. Identities = 100/211 (48%), Positives = 123/211 (59%), Gaps = 6/211 (2%) Query 87 ASPTTPSPPSQVVVPID-LWNPDGVTVDLADAVYVADSGHKRLLKLPAGSNTPTTLPFTD 145 A TTP VV+P D L P GVT D + VYV D+G++R++ LPAGS T TLPFTD Sbjct 433 AGSTTP-----VVLPFDGLSYPTGVTADNSGTVYVNDAGNRRVVVLPAGSKTQVTLPFTD 487 Query 146 TIGPGGVAVNSNRDVYVIDEDSHHVLKLAAGIEPPVELPFGSLGDAHGLAVDRSDSVYVV 205 P G++V+S+R VYV D + V+ L AG ELPF L D GL VD S +V V Sbjct 488 LSNPTGLSVDSSRTVYVTDTAKNRVVGLYAGSNTQFELPFTGLSDPTGLVVDSSGTVIVA 547 Query 206 DYDNAKVLKLPPGADTPTELPFVGLDHPYDVAVDGAGTVYVTDSGHNRVVALTAGSATPV 265 D N +VL LP GA T LPF GL P V VD G VYVT+ G+ R++ L GS+T V Sbjct 548 DGGNNRVLALPAGAQTQVTLPFTGLKQPGGVTVDSEGAVYVTNKGNGRILKLPPGSSTQV 607 Query 266 HLPFADLSFPAGVTVDRDDSVYVADLNNNRV 296 L F L P G+ VD +VYV N+ V Sbjct 608 ELHFTGLDNPWGLAVDNMGTVYVGGRNDQIV 638 Score = 147 bits (370), Expect = 3e-33, Method: Compositional matrix adjust. Identities = 85/162 (53%), Positives = 103/162 (64%), Gaps = 1/162 (0%) Query 181 VELPFGSLGDAHGLAVDRSDSVYVVDYDNAKVLKLPPGADTPTELPFVGLDHPYDVAVDG 240 V LPF L D GL+VD +VYV D + ++L L G+ TP LPF GL +P V D Sbjct 397 VVLPFTGLRDPQGLSVDSGGTVYVGDTLHNRILALFAGSTTPVVLPFDGLSYPTGVTADN 456 Query 241 AGTVYVTDSGHNRVVALTAGSATPVHLPFADLSFPAGVTVDRDDSVYVADLNNNRVLKLA 300 +GTVYV D+G+ RVV L AGS T V LPF DLS P G++VD +VYV D NRV+ L Sbjct 457 SGTVYVNDAGNRRVVVLPAGSKTQVTLPFTDLSNPTGLSVDSSRTVYVTDTAKNRVVGLY 516 Query 301 AGSNAQSQLPFTGLFSPTDVAVDNDGAVYVID-FYNRMLKLP 341 AGSN Q +LPFTGL PT + VD+ G V V D NR+L LP Sbjct 517 AGSNTQFELPFTGLSDPTGLVVDSSGTVIVADGGNNRVLALP 558 >gi|342861478|ref|ZP_08718125.1| PknD [Mycobacterium colombiense CECT 3035] gi|342130967|gb|EGT84256.1| PknD [Mycobacterium colombiense CECT 3035] Length=661 Score = 193 bits (491), Expect = 3e-47, Method: Compositional matrix adjust. Identities = 133/316 (43%), Positives = 183/316 (58%), Gaps = 26/316 (8%) Query 31 RGSWPVDSERRRYGWPRNRRTLAITGAAVVVVVTLAAIGYLIFEPKISGSSTSRQAASPT 90 R + P D++RR++ + A +V +A IGY+ +GSS S++A+ Sbjct 364 RPAVPADNKRRQW------ILVGAIAAVALVAFVMAVIGYMS-----TGSSPSKEASG-- 410 Query 91 TPSPPSQVVVP---IDL-WNPDGVTVDLADAVYVADSG-HKRLLKLPAGSNTPTTLPFTD 145 Q V+P ID +P GV ++ A V+V + G + R+++LPAG++TPT LPFT Sbjct 411 ------QSVLPFNGIDFRLSPGGVALNKAGDVFVTNQGMYGRVVELPAGASTPTVLPFTG 464 Query 146 TIGPGGVAVNSNRDVYVIDEDSHHVLKLAAGIEPPVELPFGSLGDAHGLAVDRSDSVYVV 205 P G+AV+S VYV D + + V+KLAAG LPF L G+AVD VYV Sbjct 465 LYQPQGLAVDSAGAVYVADFN-NRVVKLAAGSNNQAVLPFTGLSYPEGVAVDPQGGVYVA 523 Query 206 DYDNAKVLKLPPGADTPTELPFVGLDHPYDVAVDGAGTVYVTDSGHNRVVALTAGSATPV 265 D N++V+KL PG+ T LPF L +P VAVD AG VYV D+ +NRV+ L AG+ Sbjct 524 DRGNSRVVKLAPGSSAQTVLPFADLKNPDGVAVDTAGNVYVADTDNNRVLELPAGATAQT 583 Query 266 HLPFADLSFPAGVTVDRDDSVYVADLNNNRVLKLAAGSNAQSQLPFTGLFSPTDVAVDND 325 LPF +S P G+ VD SVYV + + +RVLKL AGSN ++L F GL +P V VD D Sbjct 584 VLPFTGISVPWGIAVDSSGSVYVTEHDTSRVLKLPAGSNTPTELKFDGLNTPLAVTVDKD 643 Query 326 GAVYVIDFYN-RMLKL 340 VYV D N R++KL Sbjct 644 QNVYVADRGNDRVVKL 659 Score = 140 bits (354), Expect = 2e-31, Method: Compositional matrix adjust. Identities = 81/164 (50%), Positives = 105/164 (65%), Gaps = 1/164 (0%) Query 96 SQVVVPI-DLWNPDGVTVDLADAVYVADSGHKRLLKLPAGSNTPTTLPFTDTIGPGGVAV 154 +Q V+P L P+GV VD VYVAD G+ R++KL GS+ T LPF D P GVAV Sbjct 497 NQAVLPFTGLSYPEGVAVDPQGGVYVADRGNSRVVKLAPGSSAQTVLPFADLKNPDGVAV 556 Query 155 NSNRDVYVIDEDSHHVLKLAAGIEPPVELPFGSLGDAHGLAVDRSDSVYVVDYDNAKVLK 214 ++ +VYV D D++ VL+L AG LPF + G+AVD S SVYV ++D ++VLK Sbjct 557 DTAGNVYVADTDNNRVLELPAGATAQTVLPFTGISVPWGIAVDSSGSVYVTEHDTSRVLK 616 Query 215 LPPGADTPTELPFVGLDHPYDVAVDGAGTVYVTDSGHNRVVALT 258 LP G++TPTEL F GL+ P V VD VYV D G++RVV LT Sbjct 617 LPAGSNTPTELKFDGLNTPLAVTVDKDQNVYVADRGNDRVVKLT 660 Score = 107 bits (267), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 61/127 (49%), Positives = 78/127 (62%), Gaps = 1/127 (0%) Query 92 PSPPSQVVVPI-DLWNPDGVTVDLADAVYVADSGHKRLLKLPAGSNTPTTLPFTDTIGPG 150 P +Q V+P DL NPDGV VD A VYVAD+ + R+L+LPAG+ T LPFT P Sbjct 535 PGSSAQTVLPFADLKNPDGVAVDTAGNVYVADTDNNRVLELPAGATAQTVLPFTGISVPW 594 Query 151 GVAVNSNRDVYVIDEDSHHVLKLAAGIEPPVELPFGSLGDAHGLAVDRSDSVYVVDYDNA 210 G+AV+S+ VYV + D+ VLKL AG P EL F L + VD+ +VYV D N Sbjct 595 GIAVDSSGSVYVTEHDTSRVLKLPAGSNTPTELKFDGLNTPLAVTVDKDQNVYVADRGND 654 Query 211 KVLKLPP 217 +V+KL P Sbjct 655 RVVKLTP 661 >gi|240171930|ref|ZP_04750589.1| transmembrane serine/threonine-protein kinase D PknD [Mycobacterium kansasii ATCC 12478] Length=722 Score = 193 bits (491), Expect = 3e-47, Method: Compositional matrix adjust. Identities = 124/262 (48%), Positives = 160/262 (62%), Gaps = 8/262 (3%) Query 86 AASPTTPSPPS-QVVVPIDLWN----PDGVTVDLADAVYVAD-SGHKRLLKLPAGSNTPT 139 A P +PP QVV+P + N P GV VD VYV + + + R++ LPA S+TPT Sbjct 458 ATRPKGSTPPQGQVVLPFNGLNFRFSPGGVAVDDQGTVYVTNQTMYGRVVTLPADSSTPT 517 Query 140 TLPFTDTIGPGGVAVNSNRDVYVIDEDSHHVLKLAAGIEPPVELPFGSLGDAHGLAVDRS 199 PF P G+AV+ + +YV D + + V+ LAAG VELPF L G+AVD Sbjct 518 VKPFNGLYEPQGLAVDGSGTIYVSDFN-NRVVSLAAGSNRQVELPFSGLNYPEGIAVDAQ 576 Query 200 DSVYVVDYDNAKVLKLPPGADTPTELPFVGLDHPYDVAVDGAGTVYVTDSGHNRVVALTA 259 SVYV D N +V+KL G+ + T LPF GL +P VAVD G VYVTD+ +NRVV L A Sbjct 577 GSVYVADRGNNRVVKLAAGSTSQTVLPFNGLKNPDGVAVDADGNVYVTDTDNNRVVKLEA 636 Query 260 GSATPVHLPFADLSFPAGVTVDRDDSVYVADLNNNRVLKLAAGSNAQSQLPFTGLFSPTD 319 G++ LPF L+ P G+TVD +VYV + +NN V KL AG+ A ++LPFTGL +P Sbjct 637 GTSNQSVLPFTGLTAPWGITVDGAGNVYVTEHDNNAVAKLPAGATASTELPFTGLNTPLS 696 Query 320 VAVDNDGAVYVIDFYN-RMLKL 340 VAVD G VYV D N R+LKL Sbjct 697 VAVDKKGNVYVADRGNGRVLKL 718 Score = 162 bits (409), Expect = 1e-37, Method: Compositional matrix adjust. Identities = 91/200 (46%), Positives = 120/200 (60%), Gaps = 1/200 (0%) Query 104 LWNPDGVTVDLADAVYVADSGHKRLLKLPAGSNTPTTLPFTDTIGPGGVAVNSNRDVYVI 163 L+ P G+ VD + +YV+D + R++ L AGSN LPF+ P G+AV++ VYV Sbjct 524 LYEPQGLAVDGSGTIYVSDF-NNRVVSLAAGSNRQVELPFSGLNYPEGIAVDAQGSVYVA 582 Query 164 DEDSHHVLKLAAGIEPPVELPFGSLGDAHGLAVDRSDSVYVVDYDNAKVLKLPPGADTPT 223 D ++ V+KLAAG LPF L + G+AVD +VYV D DN +V+KL G + Sbjct 583 DRGNNRVVKLAAGSTSQTVLPFNGLKNPDGVAVDADGNVYVTDTDNNRVVKLEAGTSNQS 642 Query 224 ELPFVGLDHPYDVAVDGAGTVYVTDSGHNRVVALTAGSATPVHLPFADLSFPAGVTVDRD 283 LPF GL P+ + VDGAG VYVT+ +N V L AG+ LPF L+ P V VD+ Sbjct 643 VLPFTGLTAPWGITVDGAGNVYVTEHDNNAVAKLPAGATASTELPFTGLNTPLSVAVDKK 702 Query 284 DSVYVADLNNNRVLKLAAGS 303 +VYVAD N RVLKLA GS Sbjct 703 GNVYVADRGNGRVLKLAQGS 722 >gi|254819498|ref|ZP_05224499.1| PknD [Mycobacterium intracellulare ATCC 13950] Length=661 Score = 189 bits (479), Expect = 7e-46, Method: Compositional matrix adjust. Identities = 127/312 (41%), Positives = 177/312 (57%), Gaps = 25/312 (8%) Query 35 PVDSERRRYGWPRNRRTLAITGAAVVVVVTLAAIGYLIFEPKISGSSTSRQAASPTTPSP 94 P+DS+R+++ ++V +A + + F ++G ++R + S Sbjct 367 PIDSKRKQW----------------IIVGAIALVALVAFIVAVAGYLSTRSSGPAQEAS- 409 Query 95 PSQVVVP---IDL-WNPDGVTVDLADAVYVADSG-HKRLLKLPAGSNTPTTLPFTDTIGP 149 Q V+P ID +P GV +D A VYV G + R++KL AGSN T LPF P Sbjct 410 -GQSVLPFNGIDFRLSPGGVALDSAGDVYVTSEGMYGRVVKLTAGSNATTVLPFHGLYQP 468 Query 150 GGVAVNSNRDVYVIDEDSHHVLKLAAGIEPPVELPFGSLGDAHGLAVDRSDSVYVVDYDN 209 G+AV+ VYV D + + V+ LAAG LPF L G+AVD +VYV D N Sbjct 469 QGLAVDGAGTVYVADFN-NRVVSLAAGSNDQKVLPFSGLSYPEGVAVDSQGAVYVADRGN 527 Query 210 AKVLKLPPGADTPTELPFVGLDHPYDVAVDGAGTVYVTDSGHNRVVALTAGSATPVHLPF 269 ++V+KL G+ T TELPF GL +P VAVD AGTVYV D+ +NR+V L A S T LPF Sbjct 528 SRVVKLAAGSKTQTELPFNGLKNPDGVAVDAAGTVYVADTDNNRIVKLDANSNTQAELPF 587 Query 270 ADLSFPAGVTVDRDDSVYVADLNNNRVLKLAAGSNAQSQLPFTGLFSPTDVAVDNDGAVY 329 ++S P G+ VD +VYV + + + VLK AGSN + LPF GL +P VAVD + +VY Sbjct 588 QNVSVPWGIAVDNSGTVYVTEHDKSDVLKFPAGSNTPTVLPFDGLNTPLAVAVDKERSVY 647 Query 330 VIDFYN-RMLKL 340 + D N R++KL Sbjct 648 IADRGNDRVVKL 659 Score = 141 bits (355), Expect = 2e-31, Method: Compositional matrix adjust. Identities = 80/163 (50%), Positives = 105/163 (65%), Gaps = 1/163 (0%) Query 97 QVVVPID-LWNPDGVTVDLADAVYVADSGHKRLLKLPAGSNTPTTLPFTDTIGPGGVAVN 155 Q V+P L P+GV VD AVYVAD G+ R++KL AGS T T LPF P GVAV+ Sbjct 498 QKVLPFSGLSYPEGVAVDSQGAVYVADRGNSRVVKLAAGSKTQTELPFNGLKNPDGVAVD 557 Query 156 SNRDVYVIDEDSHHVLKLAAGIEPPVELPFGSLGDAHGLAVDRSDSVYVVDYDNAKVLKL 215 + VYV D D++ ++KL A ELPF ++ G+AVD S +VYV ++D + VLK Sbjct 558 AAGTVYVADTDNNRIVKLDANSNTQAELPFQNVSVPWGIAVDNSGTVYVTEHDKSDVLKF 617 Query 216 PPGADTPTELPFVGLDHPYDVAVDGAGTVYVTDSGHNRVVALT 258 P G++TPT LPF GL+ P VAVD +VY+ D G++RVV LT Sbjct 618 PAGSNTPTVLPFDGLNTPLAVAVDKERSVYIADRGNDRVVKLT 660 Score = 99.0 bits (245), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 56/123 (46%), Positives = 74/123 (61%), Gaps = 1/123 (0%) Query 96 SQVVVPID-LWNPDGVTVDLADAVYVADSGHKRLLKLPAGSNTPTTLPFTDTIGPGGVAV 154 +Q +P + L NPDGV VD A VYVAD+ + R++KL A SNT LPF + P G+AV Sbjct 539 TQTELPFNGLKNPDGVAVDAAGTVYVADTDNNRIVKLDANSNTQAELPFQNVSVPWGIAV 598 Query 155 NSNRDVYVIDEDSHHVLKLAAGIEPPVELPFGSLGDAHGLAVDRSDSVYVVDYDNAKVLK 214 +++ VYV + D VLK AG P LPF L +AVD+ SVY+ D N +V+K Sbjct 599 DNSGTVYVTEHDKSDVLKFPAGSNTPTVLPFDGLNTPLAVAVDKERSVYIADRGNDRVVK 658 Query 215 LPP 217 L P Sbjct 659 LTP 661 >gi|240172492|ref|ZP_04751151.1| transmembrane serine/threonine-protein kinase D pknD [Mycobacterium kansasii ATCC 12478] Length=260 Score = 187 bits (476), Expect = 1e-45, Method: Compositional matrix adjust. Identities = 127/258 (50%), Positives = 156/258 (61%), Gaps = 8/258 (3%) Query 89 PTTPSPPSQVVVP---IDL-WNPDGVTVDLADAVYVADSG-HKRLLKLPAGSNTPTTLPF 143 P+TP+ Q V+P ID +P GV VD A VYV G + R++KL GS+T T LPF Sbjct 3 PSTPAS-GQTVLPFKGIDFRLSPGGVAVDTAGNVYVTSEGMYGRVVKLANGSSTATVLPF 61 Query 144 TDTIGPGGVAVNSNRDVYVIDEDSHHVLKLAAGIEPPVELPFGSLGDAHGLAVDRSDSVY 203 P G+AV+ VYV D + + V+ L AG LPF L G+AVD SVY Sbjct 62 NGLYQPQGLAVDGAGAVYVTDFN-NRVVMLPAGSNSQTVLPFDGLDYPEGVAVDAQGSVY 120 Query 204 VVDYDNAKVLKLPPGADTPTELPFVGLDHPYDVAVDGAGTVYVTDSGHNRVVALTAGSAT 263 V D N++V+KL GA T T LPF GL +P VAVDGAG VYV D+ +NRVV L AGS Sbjct 121 VADRGNSRVVKLAAGAKTQTVLPFDGLKNPDGVAVDGAGAVYVADTDNNRVVKLAAGSDN 180 Query 264 PVHLPFADLSFPAGVTVDRDDSVYVADLNNNRVLKLAAGSNAQSQLPFTGLFSPTDVAVD 323 L F +LS P G+ VD +VYV + N N V+KL AGSN Q+ LPFTGL +P VAVD Sbjct 181 QTVLAFRELSVPWGIAVDTVGNVYVTEHNKNDVVKLDAGSNTQTVLPFTGLNTPLAVAVD 240 Query 324 NDGAVYVIDFYN-RMLKL 340 + G VYV D N R +KL Sbjct 241 SAGNVYVADRGNDRAVKL 258 Score = 134 bits (337), Expect = 2e-29, Method: Compositional matrix adjust. Identities = 80/164 (49%), Positives = 103/164 (63%), Gaps = 1/164 (0%) Query 96 SQVVVPID-LWNPDGVTVDLADAVYVADSGHKRLLKLPAGSNTPTTLPFTDTIGPGGVAV 154 SQ V+P D L P+GV VD +VYVAD G+ R++KL AG+ T T LPF P GVAV Sbjct 96 SQTVLPFDGLDYPEGVAVDAQGSVYVADRGNSRVVKLAAGAKTQTVLPFDGLKNPDGVAV 155 Query 155 NSNRDVYVIDEDSHHVLKLAAGIEPPVELPFGSLGDAHGLAVDRSDSVYVVDYDNAKVLK 214 + VYV D D++ V+KLAAG + L F L G+AVD +VYV +++ V+K Sbjct 156 DGAGAVYVADTDNNRVVKLAAGSDNQTVLAFRELSVPWGIAVDTVGNVYVTEHNKNDVVK 215 Query 215 LPPGADTPTELPFVGLDHPYDVAVDGAGTVYVTDSGHNRVVALT 258 L G++T T LPF GL+ P VAVD AG VYV D G++R V LT Sbjct 216 LDAGSNTQTVLPFTGLNTPLAVAVDSAGNVYVADRGNDRAVKLT 259 Score = 67.8 bits (164), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 39/79 (50%), Positives = 50/79 (64%), Gaps = 4/79 (5%) Query 267 LPFADLSF---PAGVTVDRDDSVYV-ADLNNNRVLKLAAGSNAQSQLPFTGLFSPTDVAV 322 LPF + F P GV VD +VYV ++ RV+KLA GS+ + LPF GL+ P +AV Sbjct 13 LPFKGIDFRLSPGGVAVDTAGNVYVTSEGMYGRVVKLANGSSTATVLPFNGLYQPQGLAV 72 Query 323 DNDGAVYVIDFYNRMLKLP 341 D GAVYV DF NR++ LP Sbjct 73 DGAGAVYVTDFNNRVVMLP 91 >gi|333991664|ref|YP_004524278.1| serine/threonine-protein kinase [Mycobacterium sp. JDM601] gi|333487632|gb|AEF37024.1| transmembrane serine/threonine-protein kinase D PknD [Mycobacterium sp. JDM601] Length=664 Score = 187 bits (475), Expect = 2e-45, Method: Compositional matrix adjust. Identities = 121/263 (47%), Positives = 160/263 (61%), Gaps = 7/263 (2%) Query 83 SRQAASPTTPSPPSQVVVPIDL---WNPDGVTVDLADAVYVADSG-HKRLLKLPAGSNTP 138 SR +++ +PP V+ DL +P GV +D VYV+ G H R++KL AGS++ Sbjct 400 SRPSSATPVAAPPQDVLPFTDLDYRLSPGGVALDAEGNVYVSSEGMHGRVVKLAAGSDSS 459 Query 139 TTLPFTDTIGPGGVAVNSNRDVYVIDEDSHHVLKLAAGIEPPVELPFGSLGDAHGLAVDR 198 T LPF+D P G+ V+ +VY D+ V+KLAA + LPF L D G+AVD Sbjct 460 TVLPFSDQYQPRGLVVDDIGNVYF--SDASRVVKLAAADDSHTVLPFAGLDDPDGVAVDS 517 Query 199 SDSVYVVDYDNAKVLKLPPGADTPTELPFVGLDHPYDVAVDGAGTVYVTDSGHNRVVALT 258 +VYV D + VL+L G +T T LPFVGL+ P VAVD AG VYVTD+G+NRV+ L Sbjct 518 DGNVYVADRGSDLVLRLESGTNTQTALPFVGLNKPDGVAVDSAGNVYVTDTGNNRVLKLV 577 Query 259 AGSATPVHLPFADLSFPAGVTVDRDDSVYVADLNNNRVLKLAAGSNAQSQLPFTGLFSPT 318 A S V LPF + P G+ VD +VYV + N N+V+KLAAG+ LPFTGL +P Sbjct 578 AVSNEQVVLPFVGIVSPRGIAVDDGGNVYVTEHNRNKVVKLAAGAAIPVVLPFTGLNAPL 637 Query 319 DVAVDNDGAVYVIDFYN-RMLKL 340 DVAVD G VYV D N R++K+ Sbjct 638 DVAVDKHGNVYVADRGNDRVVKV 660 Score = 147 bits (371), Expect = 3e-33, Method: Compositional matrix adjust. Identities = 92/207 (45%), Positives = 123/207 (60%), Gaps = 3/207 (1%) Query 96 SQVVVPI-DLWNPDGVTVDLADAVYVADSGHKRLLKLPAGSNTPTTLPFTDTIGPGGVAV 154 S V+P D + P G+ VD VY +D+ R++KL A ++ T LPF P GVAV Sbjct 458 SSTVLPFSDQYQPRGLVVDDIGNVYFSDA--SRVVKLAAADDSHTVLPFAGLDDPDGVAV 515 Query 155 NSNRDVYVIDEDSHHVLKLAAGIEPPVELPFGSLGDAHGLAVDRSDSVYVVDYDNAKVLK 214 +S+ +VYV D S VL+L +G LPF L G+AVD + +VYV D N +VLK Sbjct 516 DSDGNVYVADRGSDLVLRLESGTNTQTALPFVGLNKPDGVAVDSAGNVYVTDTGNNRVLK 575 Query 215 LPPGADTPTELPFVGLDHPYDVAVDGAGTVYVTDSGHNRVVALTAGSATPVHLPFADLSF 274 L ++ LPFVG+ P +AVD G VYVT+ N+VV L AG+A PV LPF L+ Sbjct 576 LVAVSNEQVVLPFVGIVSPRGIAVDDGGNVYVTEHNRNKVVKLAAGAAIPVVLPFTGLNA 635 Query 275 PAGVTVDRDDSVYVADLNNNRVLKLAA 301 P V VD+ +VYVAD N+RV+K+ A Sbjct 636 PLDVAVDKHGNVYVADRGNDRVVKVDA 662 >gi|48425401|pdb|1RWI|B Chain B, Extracellular Domain Of Mycobacterium Tuberculosis Pknd gi|48425402|pdb|1RWI|A Chain A, Extracellular Domain Of Mycobacterium Tuberculosis Pknd gi|48425403|pdb|1RWL|A Chain A, Extracellular Domain Of Mycobacterium Tuberculosis Pknd Length=270 Score = 187 bits (475), Expect = 2e-45, Method: Compositional matrix adjust. Identities = 125/263 (48%), Positives = 156/263 (60%), Gaps = 9/263 (3%) Query 84 RQAASPTTPSPPSQVVVP---IDL-WNPDGVTVDLADAVYVADSG-HKRLLKLPAGSNTP 138 R + SPT S Q V+P ID +P GV VD A VYV G + R++KL GS Sbjct 1 RPSWSPTQAS--GQTVLPFTGIDFRLSPSGVAVDSAGNVYVTSEGMYGRVVKLATGSTGT 58 Query 139 TTLPFTDTIGPGGVAVNSNRDVYVIDEDSHHVLKLAAGIEPPVELPFGSLGDAHGLAVDR 198 T LPF P G+AV+ VYV D + + V+ LAAG LPF L GLAVD Sbjct 59 TVLPFNGLYQPQGLAVDGAGTVYVTDFN-NRVVTLAAGSNNQTVLPFDGLNYPEGLAVDT 117 Query 199 SDSVYVVDYDNAKVLKLPPGADTPTELPFVGLDHPYDVAVDGAGTVYVTDSGHNRVVALT 258 +VYV D N +V+KL G+ T T LPF GL+ P VAVD +G VYVTD+ +NRVV L Sbjct 118 QGAVYVADRGNNRVVKLAAGSKTQTVLPFTGLNDPDGVAVDNSGNVYVTDTDNNRVVKLE 177 Query 259 AGSATPVHLPFADLSFPAGVTVDRDDSVYVADLNNNRVLKLAAGSNAQSQLPFTGLFSPT 318 A S V LPF D++ P G+ VD +VYV + N N+V+KL AGS + LPFTGL +P Sbjct 178 AESNNQVVLPFTDITAPWGIAVDEAGTVYVTEHNTNQVVKLLAGSTTSTVLPFTGLNTPL 237 Query 319 DVAVDNDGAVYVIDFYN-RMLKL 340 VAVD+D VYV D N R++KL Sbjct 238 AVAVDSDRTVYVADRGNDRVVKL 260 Score = 162 bits (410), Expect = 8e-38, Method: Compositional matrix adjust. Identities = 96/204 (48%), Positives = 126/204 (62%), Gaps = 2/204 (0%) Query 99 VVPID-LWNPDGVTVDLADAVYVADSGHKRLLKLPAGSNTPTTLPFTDTIGPGGVAVNSN 157 V+P + L+ P G+ VD A VYV D + R++ L AGSN T LPF P G+AV++ Sbjct 60 VLPFNGLYQPQGLAVDGAGTVYVTDF-NNRVVTLAAGSNNQTVLPFDGLNYPEGLAVDTQ 118 Query 158 RDVYVIDEDSHHVLKLAAGIEPPVELPFGSLGDAHGLAVDRSDSVYVVDYDNAKVLKLPP 217 VYV D ++ V+KLAAG + LPF L D G+AVD S +VYV D DN +V+KL Sbjct 119 GAVYVADRGNNRVVKLAAGSKTQTVLPFTGLNDPDGVAVDNSGNVYVTDTDNNRVVKLEA 178 Query 218 GADTPTELPFVGLDHPYDVAVDGAGTVYVTDSGHNRVVALTAGSATPVHLPFADLSFPAG 277 ++ LPF + P+ +AVD AGTVYVT+ N+VV L AGS T LPF L+ P Sbjct 179 ESNNQVVLPFTDITAPWGIAVDEAGTVYVTEHNTNQVVKLLAGSTTSTVLPFTGLNTPLA 238 Query 278 VTVDRDDSVYVADLNNNRVLKLAA 301 V VD D +VYVAD N+RV+KL + Sbjct 239 VAVDSDRTVYVADRGNDRVVKLTS 262 >gi|306775061|ref|ZP_07413398.1| transmembrane serine/threonine-protein kinase D pknD [Mycobacterium tuberculosis SUMu001] gi|308216410|gb|EFO75809.1| transmembrane serine/threonine-protein kinase D pknD [Mycobacterium tuberculosis SUMu001] Length=659 Score = 187 bits (474), Expect = 2e-45, Method: Compositional matrix adjust. Identities = 122/274 (45%), Positives = 156/274 (57%), Gaps = 13/274 (4%) Query 48 NRRTLAITGAAVVVVVTL-AAIGYLIFEPKISGSSTSRQAASPTTPSPPSQVVVPIDL-W 105 R+ A+ GAA +V+V + AA GYL+ P S + S Q P T ID Sbjct 376 KRKVWAVVGAAAIVLVAIVAAAGYLVLRPSWSPTQASGQTVLPFTG---------IDFRL 426 Query 106 NPDGVTVDLADAVYVADSG-HKRLLKLPAGSNTPTTLPFTDTIGPGGVAVNSNRDVYVID 164 +P GV VD A VYV G + R++KL GS T LPF P G+AV+ VYV D Sbjct 427 SPSGVAVDSAGNVYVTSEGMYGRVVKLATGSTGTTVLPFNGLYQPQGLAVDGAGTVYVTD 486 Query 165 EDSHHVLKLAAGIEPPVELPFGSLGDAHGLAVDRSDSVYVVDYDNAKVLKLPPGADTPTE 224 + + V+ LAAG LPF L GLAVD +VYV D N +V+KL G+ T T Sbjct 487 FN-NRVVTLAAGSNNQTVLPFDGLNYPEGLAVDTQGAVYVADRGNNRVVKLAAGSKTQTV 545 Query 225 LPFVGLDHPYDVAVDGAGTVYVTDSGHNRVVALTAGSATPVHLPFADLSFPAGVTVDRDD 284 LPF GL+ P VAVD +G VYVTD+ +NRVV L A S V LPF D++ P G+ VD Sbjct 546 LPFTGLNDPDGVAVDNSGNVYVTDTDNNRVVKLEAESNNQVVLPFTDITAPWGIAVDEAG 605 Query 285 SVYVADLNNNRVLKLAAGSNAQSQLPFTGLFSPT 318 +VYV + N N+V+KL AGS + LPFTGL +P+ Sbjct 606 TVYVTEHNTNQVVKLLAGSTTSTVLPFTGLNTPS 639 >gi|111026929|ref|YP_708907.1| protein kinase [Rhodococcus jostii RHA1] gi|110825468|gb|ABH00749.1| probable protein kinase [Rhodococcus jostii RHA1] Length=680 Score = 184 bits (466), Expect = 3e-44, Method: Compositional matrix adjust. Identities = 113/256 (45%), Positives = 155/256 (61%), Gaps = 2/256 (0%) Query 87 ASPTTPSPPSQVVVPI-DLWNPDGVTVDLADAVYVADSGHKRLLKLPAGSNTPTTLPFTD 145 ASP P+ +Q + L +P GV VD V+VADS + R+L+L +G+ T T LPF+ Sbjct 424 ASPHPPAARTQTALAFTGLASPQGVAVDADGTVFVADSLNNRVLELASGATTQTVLPFSG 483 Query 146 TIGPGGVAVNSNRDVYVIDEDSHHVLKLAAGIEPPVELPFGSLGDAHGLAVDRSDSVYVV 205 P VAV++ +VYV D ++ VL+L AG P LPF L + G++V VYV Sbjct 484 LDDPLAVAVDARGNVYVADTGNNRVLELVAGSATPTTLPFTGLDEPLGVSVSDGGDVYVA 543 Query 206 DYDNAKVLKLPPGADTPTELPFVGLDHPYDVAVDGAGTVYVTDSGHNRVVALTAGSATPV 265 D N +VLKL G+ TPT LPF GL P DV V AG V V DS ++RV+ LTAG++TP Sbjct 544 DGGNNRVLKLAAGSATPTTLPFTGLSRPTDVTVSDAGDVIVPDSRNHRVLELTAGASTPT 603 Query 266 HLPFADLSFPAGVTVDRDDSVYVADLNNNRVLKLAAGSNAQSQLPFTGLFSPTDVAVDND 325 LPF+D+ P V V D V + L++N V +L +GS+A + LPFTGL P +A +D Sbjct 604 TLPFSDVHAPNAVAVSDDGEVLLTTLDSNDVFELESGSSAPATLPFTGLDRPAGIATGDD 663 Query 326 GAVYVIDFYN-RMLKL 340 G +Y+ D N R+L+L Sbjct 664 GHLYLSDLGNDRVLEL 679 Score = 147 bits (372), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 105/255 (42%), Positives = 136/255 (54%), Gaps = 7/255 (2%) Query 47 RNRRTLAITGAAVVVVVTLAAIGYLIFEPKISGSSTSRQAASPTTPSPPSQVVVPID-LW 105 R + LA TG A V + A G + ++ + + T Q V+P L Sbjct 432 RTQTALAFTGLASPQGVAVDADGTVFVADSLNNRVLELASGATT------QTVLPFSGLD 485 Query 106 NPDGVTVDLADAVYVADSGHKRLLKLPAGSNTPTTLPFTDTIGPGGVAVNSNRDVYVIDE 165 +P V VD VYVAD+G+ R+L+L AGS TPTTLPFT P GV+V+ DVYV D Sbjct 486 DPLAVAVDARGNVYVADTGNNRVLELVAGSATPTTLPFTGLDEPLGVSVSDGGDVYVADG 545 Query 166 DSHHVLKLAAGIEPPVELPFGSLGDAHGLAVDRSDSVYVVDYDNAKVLKLPPGADTPTEL 225 ++ VLKLAAG P LPF L + V + V V D N +VL+L GA TPT L Sbjct 546 GNNRVLKLAAGSATPTTLPFTGLSRPTDVTVSDAGDVIVPDSRNHRVLELTAGASTPTTL 605 Query 226 PFVGLDHPYDVAVDGAGTVYVTDSGHNRVVALTAGSATPVHLPFADLSFPAGVTVDRDDS 285 PF + P VAV G V +T N V L +GS+ P LPF L PAG+ D Sbjct 606 PFSDVHAPNAVAVSDDGEVLLTTLDSNDVFELESGSSAPATLPFTGLDRPAGIATGDDGH 665 Query 286 VYVADLNNNRVLKLA 300 +Y++DL N+RVL+LA Sbjct 666 LYLSDLGNDRVLELA 680 >gi|254776673|ref|ZP_05218189.1| serine/threonine-protein kinase PknD [Mycobacterium avium subsp. avium ATCC 25291] Length=656 Score = 183 bits (465), Expect = 3e-44, Method: Compositional matrix adjust. Identities = 129/302 (43%), Positives = 169/302 (56%), Gaps = 22/302 (7%) Query 48 NRRTLAITGAAVVVVVT---LAAIGYLIFEPKISGSSTSRQAASPTTPSPPSQVVVP--- 101 R+ I GA +V + +A +GYL + S ++QA Q V+P Sbjct 366 KRKQWIIVGAVALVALVAFVVAFVGYL----STASSGPAKQAGG--------QSVLPFNG 413 Query 102 IDL-WNPDGVTVDLADAVYVADSG-HKRLLKLPAGSNTPTTLPFTDTIGPGGVAVNSNRD 159 ID +P GVT+D A VYV G + R++KL AGS T LPF P G+AV+ Sbjct 414 IDFRLSPGGVTLDGAGNVYVTSEGMYGRVVKLAAGSGATTVLPFNGLYQPQGLAVDGAGT 473 Query 160 VYVIDEDSHHVLKLAAGIEPPVELPFGSLGDAHGLAVDRSDSVYVVDYDNAKVLKLPPGA 219 VYV D + + VL +AAG ELPF L G+AVD VYV D N++VLKL G+ Sbjct 474 VYVADFN-NRVLSMAAGSNSQKELPFSGLNYPEGVAVDSQGGVYVADRGNSRVLKLAAGS 532 Query 220 DTPTELPFVGLDHPYDVAVDGAGTVYVTDSGHNRVVALTAGSATPVHLPFADLSFPAGVT 279 T LPF GL++P VAVD AG VYV D+ +NRVV L A S T LPF DLS P G+ Sbjct 533 QNQTVLPFTGLNNPDGVAVDPAGNVYVADTDNNRVVKLDAASNTQSELPFHDLSVPWGIA 592 Query 280 VDRDDSVYVADLNNNRVLKLAAGSNAQSQLPFTGLFSPTDVAVDNDGAVYVIDFY-NRML 338 VD +VYV + + N V+K G+ + + LPFT L +P VAVD D +VYV D +R++ Sbjct 593 VDNGGTVYVTEHDKNDVVKYPPGATSGTVLPFTALNTPLAVAVDRDQSVYVADRGDDRVV 652 Query 339 KL 340 KL Sbjct 653 KL 654 Score = 161 bits (408), Expect = 1e-37, Method: Compositional matrix adjust. Identities = 97/203 (48%), Positives = 127/203 (63%), Gaps = 2/203 (0%) Query 99 VVPID-LWNPDGVTVDLADAVYVADSGHKRLLKLPAGSNTPTTLPFTDTIGPGGVAVNSN 157 V+P + L+ P G+ VD A VYVAD + R+L + AGSN+ LPF+ P GVAV+S Sbjct 454 VLPFNGLYQPQGLAVDGAGTVYVADF-NNRVLSMAAGSNSQKELPFSGLNYPEGVAVDSQ 512 Query 158 RDVYVIDEDSHHVLKLAAGIEPPVELPFGSLGDAHGLAVDRSDSVYVVDYDNAKVLKLPP 217 VYV D + VLKLAAG + LPF L + G+AVD + +VYV D DN +V+KL Sbjct 513 GGVYVADRGNSRVLKLAAGSQNQTVLPFTGLNNPDGVAVDPAGNVYVADTDNNRVVKLDA 572 Query 218 GADTPTELPFVGLDHPYDVAVDGAGTVYVTDSGHNRVVALTAGSATPVHLPFADLSFPAG 277 ++T +ELPF L P+ +AVD GTVYVT+ N VV G+ + LPF L+ P Sbjct 573 ASNTQSELPFHDLSVPWGIAVDNGGTVYVTEHDKNDVVKYPPGATSGTVLPFTALNTPLA 632 Query 278 VTVDRDDSVYVADLNNNRVLKLA 300 V VDRD SVYVAD ++RV+KLA Sbjct 633 VAVDRDQSVYVADRGDDRVVKLA 655 Score = 129 bits (325), Expect = 6e-28, Method: Compositional matrix adjust. Identities = 79/153 (52%), Positives = 100/153 (66%), Gaps = 3/153 (1%) Query 193 GLAVDRSDSVYVVDYDN-AKVLKLPPGADTPTELPFVGLDHPYDVAVDGAGTVYVTDSGH 251 G+ +D + +VYV +V+KL G+ T LPF GL P +AVDGAGTVYV D + Sbjct 422 GVTLDGAGNVYVTSEGMYGRVVKLAAGSGATTVLPFNGLYQPQGLAVDGAGTVYVADF-N 480 Query 252 NRVVALTAGSATPVHLPFADLSFPAGVTVDRDDSVYVADLNNNRVLKLAAGSNAQSQLPF 311 NRV+++ AGS + LPF+ L++P GV VD VYVAD N+RVLKLAAGS Q+ LPF Sbjct 481 NRVLSMAAGSNSQKELPFSGLNYPEGVAVDSQGGVYVADRGNSRVLKLAAGSQNQTVLPF 540 Query 312 TGLFSPTDVAVDNDGAVYVIDF-YNRMLKLPTA 343 TGL +P VAVD G VYV D NR++KL A Sbjct 541 TGLNNPDGVAVDPAGNVYVADTDNNRVVKLDAA 573 >gi|240170030|ref|ZP_04748689.1| transmembrane serine/threonine-protein kinase D [Mycobacterium kansasii ATCC 12478] Length=621 Score = 179 bits (455), Expect = 5e-43, Method: Compositional matrix adjust. Identities = 122/269 (46%), Positives = 157/269 (59%), Gaps = 6/269 (2%) Query 77 ISGSSTSR---QAASPTTPSPPSQVVVPI-DLWNPDGVTVDLADAVYVADSGHKRLLKLP 132 I+G+ T+ Q A P+ P P+ VV+P L P V V AVYV D + R+++L Sbjct 351 IAGNPTAHPVSQVAGPSEPLRPAPVVLPFTGLDGPTPVAVGPGGAVYVGDYYNNRVVQLA 410 Query 133 AGSNTPTTLPFTDTIGPGGVAVNSNRDVYVIDEDSHHVLKLAAGIEPPVELPFGSLGDAH 192 +GS T LPFT P +AV+S VYV VL L AG +L D+ Sbjct 411 SGSFAETELPFTGLNRPQSLAVDSTGTVYVSGARGE-VLTLPAGAASASKLADTGAEDSA 469 Query 193 GLAVDRSDSVYVVDYDNAKVLKLPPGADTPTELPFVGLDHPYDVAVDGAGTVYVTDSGHN 252 GLAVD + +VYVVD N +VLKLP G T LPF GL P VAVD +G VYV D+ +N Sbjct 470 GLAVDTARNVYVVDTPNNRVLKLPGGGGPQTVLPFTGLKAPAGVAVDSSGAVYVCDAYNN 529 Query 253 RVVALTAGSATPVHLPFADLSFPAGVTVDRDDSVYVADLNNNRVLKLAAGSNAQSQLPFT 312 RV+ L AG++T + LPF +L FP V VD+ +VYV+D N++LKL AG++ Q+ LP Sbjct 530 RVLKLPAGASTQIVLPFTELVFPTAVAVDKTGAVYVSDSPKNQILKLPAGADFQTVLPLG 589 Query 313 GLFSPTDVAVDNDGAVYVIDF-YNRMLKL 340 GL P VAVD G VYV D NR+LKL Sbjct 590 GLNHPEGVAVDEAGNVYVTDSNNNRVLKL 618 Score = 71.2 bits (173), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 39/78 (50%), Positives = 49/78 (63%), Gaps = 0/78 (0%) Query 264 PVHLPFADLSFPAGVTVDRDDSVYVADLNNNRVLKLAAGSNAQSQLPFTGLFSPTDVAVD 323 PV LPF L P V V +VYV D NNRV++LA+GS A+++LPFTGL P +AVD Sbjct 374 PVVLPFTGLDGPTPVAVGPGGAVYVGDYYNNRVVQLASGSFAETELPFTGLNRPQSLAVD 433 Query 324 NDGAVYVIDFYNRMLKLP 341 + G VYV +L LP Sbjct 434 STGTVYVSGARGEVLTLP 451 >gi|118465473|ref|YP_883379.1| serine/threonine protein kinase [Mycobacterium avium 104] gi|118166760|gb|ABK67657.1| serine/threonine-protein kinase PknD [Mycobacterium avium 104] Length=656 Score = 179 bits (453), Expect = 8e-43, Method: Compositional matrix adjust. Identities = 117/250 (47%), Positives = 149/250 (60%), Gaps = 7/250 (2%) Query 97 QVVVP---IDL-WNPDGVTVDLADAVYVADSG-HKRLLKLPAGSNTPTTLPFTDTIGPGG 151 Q V+P ID +P GVT+D A VYV G + R++KL AGS T LPF P G Sbjct 406 QSVLPFNGIDFRLSPGGVTLDGAGNVYVTSEGMYGRVVKLAAGSGATTVLPFNGLYQPQG 465 Query 152 VAVNSNRDVYVIDEDSHHVLKLAAGIEPPVELPFGSLGDAHGLAVDRSDSVYVVDYDNAK 211 +AV+ VYV D + + VL +AAG ELPF L G+AVD VYV D N++ Sbjct 466 LAVDGAGTVYVADFN-NRVLSMAAGSNSQKELPFSGLNYPEGVAVDSQGGVYVADRGNSR 524 Query 212 VLKLPPGADTPTELPFVGLDHPYDVAVDGAGTVYVTDSGHNRVVALTAGSATPVHLPFAD 271 VLKL G+ T LPF GL++P VAVD AG VYV D+ +NRVV L A S T LPF D Sbjct 525 VLKLAAGSQNQTVLPFTGLNNPDGVAVDPAGNVYVADTDNNRVVKLDAASNTQSELPFHD 584 Query 272 LSFPAGVTVDRDDSVYVADLNNNRVLKLAAGSNAQSQLPFTGLFSPTDVAVDNDGAVYVI 331 LS P G+ VD +VYV + + N V+K G+ + + LPFT L +P VAVD D +VYV Sbjct 585 LSVPWGIAVDNGGTVYVTEHDKNDVVKYPPGATSGTVLPFTALNTPLAVAVDRDQSVYVA 644 Query 332 DFY-NRMLKL 340 D +R++KL Sbjct 645 DRGDDRVVKL 654 Score = 161 bits (407), Expect = 2e-37, Method: Compositional matrix adjust. Identities = 97/203 (48%), Positives = 127/203 (63%), Gaps = 2/203 (0%) Query 99 VVPID-LWNPDGVTVDLADAVYVADSGHKRLLKLPAGSNTPTTLPFTDTIGPGGVAVNSN 157 V+P + L+ P G+ VD A VYVAD + R+L + AGSN+ LPF+ P GVAV+S Sbjct 454 VLPFNGLYQPQGLAVDGAGTVYVADF-NNRVLSMAAGSNSQKELPFSGLNYPEGVAVDSQ 512 Query 158 RDVYVIDEDSHHVLKLAAGIEPPVELPFGSLGDAHGLAVDRSDSVYVVDYDNAKVLKLPP 217 VYV D + VLKLAAG + LPF L + G+AVD + +VYV D DN +V+KL Sbjct 513 GGVYVADRGNSRVLKLAAGSQNQTVLPFTGLNNPDGVAVDPAGNVYVADTDNNRVVKLDA 572 Query 218 GADTPTELPFVGLDHPYDVAVDGAGTVYVTDSGHNRVVALTAGSATPVHLPFADLSFPAG 277 ++T +ELPF L P+ +AVD GTVYVT+ N VV G+ + LPF L+ P Sbjct 573 ASNTQSELPFHDLSVPWGIAVDNGGTVYVTEHDKNDVVKYPPGATSGTVLPFTALNTPLA 632 Query 278 VTVDRDDSVYVADLNNNRVLKLA 300 V VDRD SVYVAD ++RV+KLA Sbjct 633 VAVDRDQSVYVADRGDDRVVKLA 655 Score = 129 bits (324), Expect = 7e-28, Method: Compositional matrix adjust. Identities = 79/153 (52%), Positives = 100/153 (66%), Gaps = 3/153 (1%) Query 193 GLAVDRSDSVYVVDYDN-AKVLKLPPGADTPTELPFVGLDHPYDVAVDGAGTVYVTDSGH 251 G+ +D + +VYV +V+KL G+ T LPF GL P +AVDGAGTVYV D + Sbjct 422 GVTLDGAGNVYVTSEGMYGRVVKLAAGSGATTVLPFNGLYQPQGLAVDGAGTVYVADF-N 480 Query 252 NRVVALTAGSATPVHLPFADLSFPAGVTVDRDDSVYVADLNNNRVLKLAAGSNAQSQLPF 311 NRV+++ AGS + LPF+ L++P GV VD VYVAD N+RVLKLAAGS Q+ LPF Sbjct 481 NRVLSMAAGSNSQKELPFSGLNYPEGVAVDSQGGVYVADRGNSRVLKLAAGSQNQTVLPF 540 Query 312 TGLFSPTDVAVDNDGAVYVIDF-YNRMLKLPTA 343 TGL +P VAVD G VYV D NR++KL A Sbjct 541 TGLNNPDGVAVDPAGNVYVADTDNNRVVKLDAA 573 >gi|111025322|ref|YP_707742.1| serine/threonine protein kinase [Rhodococcus jostii RHA1] gi|110824301|gb|ABG99584.1| serine/threonine protein kinase [Rhodococcus jostii RHA1] Length=653 Score = 178 bits (452), Expect = 1e-42, Method: Compositional matrix adjust. Identities = 123/310 (40%), Positives = 169/310 (55%), Gaps = 15/310 (4%) Query 36 VDSERRRYGWPRNRRTLAITGAAVVVVVTLAAIGYLIFEPKISGSSTSRQAASPTTPSPP 95 ++ R R W R T+ I A ++ ++ +A +G +++ + + T+ T P Sbjct 351 LEHPRARIRWWRRTSTVVI--AVILTLLAVATVGVVVYRQTQTPTQTTETETETQTQLPF 408 Query 96 SQVVVPIDLWNPDGVTVDLADAVYVADSGHKRLLKLPAGSNTPTTLPFTDTIGPGGVAVN 155 + L P+GV VD +VYV D + ++LKL AGS T T LPFT P GV V+ Sbjct 409 TS------LSQPEGVAVDTVGSVYVTDHDNNQVLKLAAGSTTQTVLPFTGLSQPEGVTVD 462 Query 156 SNRDVYVIDEDSHHVLKLAAGIEPPVELPFGSLGDAHGLAVDRSDSVYVVD----YDNAK 211 + VYV D D++ VLKL AG LPF L G+AVD S +YV D + + Sbjct 463 TVGSVYVTDHDNNRVLKLTAGSNSATALPFTDLRYPRGVAVDGSGGIYVTDTGTGRGDGR 522 Query 212 VLKLPPGADTPTELPFVGLDHPYDVAVDGAGTVYVTDSGHNRVVALTAGSATPVHLPFAD 271 VLKL G+ T LPF G VA++ A V+ + +RV+ L GS + LPF D Sbjct 523 VLKLAAGSTTQIVLPFTG--ETDWVALNAAEDVFFSQFLGSRVMMLAGGSNSATALPFTD 580 Query 272 LSFPAGVTVDRDDSVYVADLNNNRVLKLAAGSNAQSQLPFTGLFSPTDVAVDNDGAVYVI 331 L P+GV VD +VYVAD N RVLKL AGS Q++LPFTG+ PT VA+D G VYV Sbjct 581 LYDPSGVAVDTTGTVYVADSGNARVLKLVAGSTTQTELPFTGISGPTGVAIDTAGNVYVA 640 Query 332 DF-YNRMLKL 340 D + R+L+L Sbjct 641 DTDHGRVLRL 650 Score = 159 bits (402), Expect = 6e-37, Method: Compositional matrix adjust. Identities = 97/212 (46%), Positives = 131/212 (62%), Gaps = 7/212 (3%) Query 96 SQVVVPI-DLWNPDGVTVDLADAVYVADSGHKRLLKLPAGSNTPTTLPFTDTIGPGGVAV 154 +Q V+P L P+GVTVD +VYV D + R+LKL AGSN+ T LPFTD P GVAV Sbjct 444 TQTVLPFTGLSQPEGVTVDTVGSVYVTDHDNNRVLKLTAGSNSATALPFTDLRYPRGVAV 503 Query 155 NSNRDVYVIDEDSHH----VLKLAAGIEPPVELPFGSLGDAHGLAVDRSDSVYVVDYDNA 210 + + +YV D + VLKLAAG + LPF G+ +A++ ++ V+ + + Sbjct 504 DGSGGIYVTDTGTGRGDGRVLKLAAGSTTQIVLPF--TGETDWVALNAAEDVFFSQFLGS 561 Query 211 KVLKLPPGADTPTELPFVGLDHPYDVAVDGAGTVYVTDSGHNRVVALTAGSATPVHLPFA 270 +V+ L G+++ T LPF L P VAVD GTVYV DSG+ RV+ L AGS T LPF Sbjct 562 RVMMLAGGSNSATALPFTDLYDPSGVAVDTTGTVYVADSGNARVLKLVAGSTTQTELPFT 621 Query 271 DLSFPAGVTVDRDDSVYVADLNNNRVLKLAAG 302 +S P GV +D +VYVAD ++ RVL+LAAG Sbjct 622 GISGPTGVAIDTAGNVYVADTDHGRVLRLAAG 653 >gi|41409485|ref|NP_962321.1| PknD [Mycobacterium avium subsp. paratuberculosis K-10] gi|41398316|gb|AAS05937.1| PknD [Mycobacterium avium subsp. paratuberculosis K-10] Length=656 Score = 177 bits (450), Expect = 2e-42, Method: Compositional matrix adjust. Identities = 116/250 (47%), Positives = 148/250 (60%), Gaps = 7/250 (2%) Query 97 QVVVP---IDL-WNPDGVTVDLADAVYVADSG-HKRLLKLPAGSNTPTTLPFTDTIGPGG 151 Q V+P ID +P GVT+D VYV G + R++KL AGS T LPF P G Sbjct 406 QSVLPFNGIDFRLSPGGVTLDGTGNVYVTSEGMYGRVVKLAAGSGATTVLPFNGLYQPQG 465 Query 152 VAVNSNRDVYVIDEDSHHVLKLAAGIEPPVELPFGSLGDAHGLAVDRSDSVYVVDYDNAK 211 +AV+ VYV D + + VL +AAG ELPF L G+AVD VYV D N++ Sbjct 466 LAVDGAGTVYVADFN-NRVLSMAAGSNSQKELPFSGLNYPEGVAVDSQGGVYVADRGNSR 524 Query 212 VLKLPPGADTPTELPFVGLDHPYDVAVDGAGTVYVTDSGHNRVVALTAGSATPVHLPFAD 271 VLKL G+ T LPF GL++P VAVD AG VYV D+ +NRVV L A S T LPF D Sbjct 525 VLKLAAGSQNQTVLPFTGLNNPDGVAVDPAGNVYVADTDNNRVVKLDAASNTQSELPFHD 584 Query 272 LSFPAGVTVDRDDSVYVADLNNNRVLKLAAGSNAQSQLPFTGLFSPTDVAVDNDGAVYVI 331 LS P G+ VD +VYV + + N V+K G+ + + LPFT L +P VAVD D +VYV Sbjct 585 LSVPWGIAVDNGGTVYVTEHDKNDVMKYPPGATSGTVLPFTALNTPLAVAVDRDQSVYVA 644 Query 332 DFY-NRMLKL 340 D +R++KL Sbjct 645 DRGDDRVVKL 654 Score = 129 bits (324), Expect = 7e-28, Method: Compositional matrix adjust. Identities = 79/153 (52%), Positives = 100/153 (66%), Gaps = 3/153 (1%) Query 193 GLAVDRSDSVYVVDYDN-AKVLKLPPGADTPTELPFVGLDHPYDVAVDGAGTVYVTDSGH 251 G+ +D + +VYV +V+KL G+ T LPF GL P +AVDGAGTVYV D + Sbjct 422 GVTLDGTGNVYVTSEGMYGRVVKLAAGSGATTVLPFNGLYQPQGLAVDGAGTVYVADF-N 480 Query 252 NRVVALTAGSATPVHLPFADLSFPAGVTVDRDDSVYVADLNNNRVLKLAAGSNAQSQLPF 311 NRV+++ AGS + LPF+ L++P GV VD VYVAD N+RVLKLAAGS Q+ LPF Sbjct 481 NRVLSMAAGSNSQKELPFSGLNYPEGVAVDSQGGVYVADRGNSRVLKLAAGSQNQTVLPF 540 Query 312 TGLFSPTDVAVDNDGAVYVIDF-YNRMLKLPTA 343 TGL +P VAVD G VYV D NR++KL A Sbjct 541 TGLNNPDGVAVDPAGNVYVADTDNNRVVKLDAA 573 >gi|296168857|ref|ZP_06850529.1| possible non-specific serine/threonine protein kinase [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295896474|gb|EFG76124.1| possible non-specific serine/threonine protein kinase [Mycobacterium parascrofulaceum ATCC BAA-614] Length=854 Score = 160 bits (406), Expect = 2e-37, Method: Compositional matrix adjust. Identities = 107/256 (42%), Positives = 140/256 (55%), Gaps = 8/256 (3%) Query 93 SPPSQVVVPI-DLWNPDGVTVDLADAVYVADSGHKRLLKLPAGSNTPTTLPFTDTIGPGG 151 P QVV+P L NP V VD VYV D+G+ R+L+L AGS + T +P P Sbjct 593 KPKGQVVLPFTGLDNPQRVAVDSKGDVYVTDTGNNRVLRLAAGSTSQTVIPIAGLDRPLD 652 Query 152 VAVNSNRDVYVIDEDSHHVLKLAAGIEPPVELPFGSLGDAHGLAVDRSDS-----VYVVD 206 +AV+ D+ V + H VL+LAAG P LPF LGD G+AVD DS V V D Sbjct 653 IAVDDAGDLDVTEPAQHRVLELAAGSTDPTVLPFTDLGDPTGVAVDFGDSGHDRVVVVTD 712 Query 207 YDNAKVLKLPPGADTPTELPFVGLDHPYDVAVDGAGTVYVTDSGHNRVVALTAGSATPVH 266 +V+ L + ELPF GL P V V GAG +V D + RV+ L P Sbjct 713 CARNRVVALRGRSTQQKELPFSGLSCPSAVTVGGAGDFFVIDRENERVLRLPLRGTVPTV 772 Query 267 LPFADLSFPAGVTVDRDDSVYVADLNNNRVLKLAAGSNAQSQLPFTGLFSPTDVAVDNDG 326 LPF + P V VD +VYV D+++NRV + AA SN +PF G+ +P ++VD+ G Sbjct 773 LPFL-VGHPDNVAVDTSGNVYVTDVHDNRVTEFAAASNTSEAMPFKGINNPQGISVDSAG 831 Query 327 AVYVIDF-YNRMLKLP 341 VYV+D NR+LKLP Sbjct 832 NVYVVDTGNNRVLKLP 847 Score = 60.8 bits (146), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 32/79 (41%), Positives = 47/79 (60%), Gaps = 0/79 (0%) Query 99 VVPIDLWNPDGVTVDLADAVYVADSGHKRLLKLPAGSNTPTTLPFTDTIGPGGVAVNSNR 158 V+P + +PD V VD + VYV D R+ + A SNT +PF P G++V+S Sbjct 772 VLPFLVGHPDNVAVDTSGNVYVTDVHDNRVTEFAAASNTSEAMPFKGINNPQGISVDSAG 831 Query 159 DVYVIDEDSHHVLKLAAGI 177 +VYV+D ++ VLKL AG+ Sbjct 832 NVYVVDTGNNRVLKLPAGV 850 >gi|111017527|ref|YP_700499.1| serine/threonine-protein kinase [Rhodococcus jostii RHA1] gi|110817057|gb|ABG92341.1| serine/threonine-protein kinase [Rhodococcus jostii RHA1] Length=619 Score = 160 bits (405), Expect = 3e-37, Method: Compositional matrix adjust. Identities = 98/206 (48%), Positives = 127/206 (62%), Gaps = 1/206 (0%) Query 128 LLKLPAGSNTPTTLPFTDTIGPGGVAVNSNRDVYVIDEDSHHVLKLAAGIEPPVELPFGS 187 + P S T TTLPF P GVAVN+ D+ V D +++ VL+LAAG LPF Sbjct 363 FVSWPNRSATQTTLPFEGLDYPVGVAVNTAGDLVVADSNNNRVLRLAAGAGAQEVLPFTD 422 Query 188 LGDAHGLAVDRSDSVYVVDYDNAKVLKLPPGADTPTELPFVGLDHPYDVAVDGAGTVYVT 247 L G+A + + V+V D N +VL+L GA T T LPF GL P VAV AG ++V Sbjct 423 LDHPSGVATNGAGDVFVADTRNNRVLELAAGATTQTVLPFTGLAGPAGVAVSDAGHLFVA 482 Query 248 DSGHNRVVALTAGSATPVHLPFADLSFPAGVTVDRDDSVYVADLNNNRVLKLAAGSNAQS 307 D+ +NR+VAL AG+A+P LP +DL P GV V+ V+V D +NNRVL L AG+ Q+ Sbjct 483 DNNNNRIVALPAGAASPQVLPLSDLHGPVGVAVNSGGDVFVTDTDNNRVLFLPAGATDQT 542 Query 308 QLPFTGLFSPTDVAVDNDGAVYVIDF 333 LPFTGL SPT VA D+ G V+V D+ Sbjct 543 VLPFTGLASPTGVAADSTG-VFVADY 567 Score = 154 bits (389), Expect = 2e-35, Method: Compositional matrix adjust. Identities = 101/246 (42%), Positives = 140/246 (57%), Gaps = 3/246 (1%) Query 96 SQVVVPID-LWNPDGVTVDLADAVYVADSGHKRLLKLPAGSNTPTTLPFTDTIGPGGVAV 154 +Q +P + L P GV V+ A + VADS + R+L+L AG+ LPFTD P GVA Sbjct 372 TQTTLPFEGLDYPVGVAVNTAGDLVVADSNNNRVLRLAAGAGAQEVLPFTDLDHPSGVAT 431 Query 155 NSNRDVYVIDEDSHHVLKLAAGIEPPVELPFGSLGDAHGLAVDRSDSVYVVDYDNAKVLK 214 N DV+V D ++ VL+LAAG LPF L G+AV + ++V D +N +++ Sbjct 432 NGAGDVFVADTRNNRVLELAAGATTQTVLPFTGLAGPAGVAVSDAGHLFVADNNNNRIVA 491 Query 215 LPPGADTPTELPFVGLDHPYDVAVDGAGTVYVTDSGHNRVVALTAGSATPVHLPFADLSF 274 LP GA +P LP L P VAV+ G V+VTD+ +NRV+ L AG+ LPF L+ Sbjct 492 LPAGAASPQVLPLSDLHGPVGVAVNSGGDVFVTDTDNNRVLFLPAGATDQTVLPFTGLAS 551 Query 275 PAGVTVDRDDSVYVADLNNNRVLKLAAGSNAQSQLPFTGLFSPTDVAVDNDGAVYVIDFY 334 P GV D V+VAD RV+ L AG++ + + FTGL P VAV G + V D Sbjct 552 PTGVAAD-STGVFVADYGGGRVVALRAGADTPAVVRFTGLHGPIWVAVTATGDLVVTD-G 609 Query 335 NRMLKL 340 +R+L+L Sbjct 610 DRVLQL 615 Score = 121 bits (303), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 72/160 (45%), Positives = 97/160 (61%), Gaps = 1/160 (0%) Query 183 LPFGSLGDAHGLAVDRSDSVYVVDYDNAKVLKLPPGADTPTELPFVGLDHPYDVAVDGAG 242 LPF L G+AV+ + + V D +N +VL+L GA LPF LDHP VA +GAG Sbjct 376 LPFEGLDYPVGVAVNTAGDLVVADSNNNRVLRLAAGAGAQEVLPFTDLDHPSGVATNGAG 435 Query 243 TVYVTDSGHNRVVALTAGSATPVHLPFADLSFPAGVTVDRDDSVYVADLNNNRVLKLAAG 302 V+V D+ +NRV+ L AG+ T LPF L+ PAGV V ++VAD NNNR++ L AG Sbjct 436 DVFVADTRNNRVLELAAGATTQTVLPFTGLAGPAGVAVSDAGHLFVADNNNNRIVALPAG 495 Query 303 SNAQSQLPFTGLFSPTDVAVDNDGAVYVIDF-YNRMLKLP 341 + + LP + L P VAV++ G V+V D NR+L LP Sbjct 496 AASPQVLPLSDLHGPVGVAVNSGGDVFVTDTDNNRVLFLP 535 Score = 111 bits (277), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 72/164 (44%), Positives = 95/164 (58%), Gaps = 4/164 (2%) Query 96 SQVVVPI-DLWNPDGVTVDLADAVYVADSGHKRLLKLPAGSNTPTTLPFTDTIGPGGVAV 154 +Q V+P L P GV V A ++VAD+ + R++ LPAG+ +P LP +D GP GVAV Sbjct 456 TQTVLPFTGLAGPAGVAVSDAGHLFVADNNNNRIVALPAGAASPQVLPLSDLHGPVGVAV 515 Query 155 NSNRDVYVIDEDSHHVLKLAAGIEPPVELPFGSLGDAHGLAVDRSDSVYVVDYDNAKVLK 214 NS DV+V D D++ VL L AG LPF L G+A D S V+V DY +V+ Sbjct 516 NSGGDVFVTDTDNNRVLFLPAGATDQTVLPFTGLASPTGVAAD-STGVFVADYGGGRVVA 574 Query 215 LPPGADTPTELPFVGLDHPYDVAVDGAGTVYVTDSGHNRVVALT 258 L GADTP + F GL P VAV G + VTD +RV+ L+ Sbjct 575 LRAGADTPAVVRFTGLHGPIWVAVTATGDLVVTDG--DRVLQLS 616 Score = 110 bits (274), Expect = 4e-22, Method: Compositional matrix adjust. Identities = 62/122 (51%), Positives = 79/122 (65%), Gaps = 1/122 (0%) Query 221 TPTELPFVGLDHPYDVAVDGAGTVYVTDSGHNRVVALTAGSATPVHLPFADLSFPAGVTV 280 T T LPF GLD+P VAV+ AG + V DS +NRV+ L AG+ LPF DL P+GV Sbjct 372 TQTTLPFEGLDYPVGVAVNTAGDLVVADSNNNRVLRLAAGAGAQEVLPFTDLDHPSGVAT 431 Query 281 DRDDSVYVADLNNNRVLKLAAGSNAQSQLPFTGLFSPTDVAVDNDGAVYVID-FYNRMLK 339 + V+VAD NNRVL+LAAG+ Q+ LPFTGL P VAV + G ++V D NR++ Sbjct 432 NGAGDVFVADTRNNRVLELAAGATTQTVLPFTGLAGPAGVAVSDAGHLFVADNNNNRIVA 491 Query 340 LP 341 LP Sbjct 492 LP 493 >gi|296170643|ref|ZP_06852218.1| non-specific serine/threonine protein kinase [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295894632|gb|EFG74366.1| non-specific serine/threonine protein kinase [Mycobacterium parascrofulaceum ATCC BAA-614] Length=339 Score = 154 bits (390), Expect = 1e-35, Method: Compositional matrix adjust. Identities = 124/318 (39%), Positives = 168/318 (53%), Gaps = 27/318 (8%) Query 38 SERRRYGWPRNRRTLAITGAAVVVVVTLAAIGYLIFEPKISGSSTSRQAASPTT------ 91 S+ R W R + L + V +V+ L A G L++ P R A +P T Sbjct 31 SDPERSWWRRRKWALVV----VAIVMALLA-GVLVYAP------IHRHAPAPPTAPSSRA 79 Query 92 -PSPPSQVVVPID-LWNPDGVTVDLADAVYVADSGHKRLLKLPAGSNTPTTLPFTDTIGP 149 P+ P+ VVP L +P G+ VD A VYVAD+G+ R+LKL S T +PF D P Sbjct 80 KPATPAASVVPFTGLSHPTGIAVDAARNVYVADTGNNRVLKLAPESGTQEVIPFADLNRP 139 Query 150 GGVAVNSNRDVYVIDEDSHHVLKLAAGIEPPVELPFGSLGDAHGLAVDRSDSVYVVDYDN 209 GVAV+++ VY +D ++ VLKLA G LPF L GL VD + +VYV D Sbjct 140 FGVAVDADGAVYTVD-NTQRVLKLAPGRSTQQVLPFNGLSSVGGLTVDSAGNVYVADTGK 198 Query 210 AKVLKLPPGADTPTELPFVGLDHPYDVAVDGAGTVYVTDSGHNRVVALTAGSATPVHLPF 269 +V+KL ++T + F L +P DVAVD AG VYVT+ +RV L A S L F Sbjct 199 NQVVKLVAASNTQQVVGFSDLFYPGDVAVDPAGNVYVTEIWTDRVRVLAADSGRQRELSF 258 Query 270 ADLSFPA---GVTVDRDDSVYVADLNNNR---VLKLAAGSNAQSQLPFTGLFSPTDVAVD 323 + V VD V+V D + V++LAAGS A LPF+ L +P VAVD Sbjct 259 DHDLYQIHVFAVAVDPAGDVFVTDNFQGQGYWVVELAAGSRAPKVLPFSALDAPNGVAVD 318 Query 324 NDGAVYVIDF-YNRMLKL 340 + G+VYV D +NR++KL Sbjct 319 SAGSVYVADAGHNRVVKL 336 Score = 119 bits (297), Expect = 9e-25, Method: Compositional matrix adjust. Identities = 71/161 (45%), Positives = 94/161 (59%), Gaps = 1/161 (0%) Query 183 LPFGSLGDAHGLAVDRSDSVYVVDYDNAKVLKLPPGADTPTELPFVGLDHPYDVAVDGAG 242 +PF L G+AVD + +VYV D N +VLKL P + T +PF L+ P+ VAVD G Sbjct 89 VPFTGLSHPTGIAVDAARNVYVADTGNNRVLKLAPESGTQEVIPFADLNRPFGVAVDADG 148 Query 243 TVYVTDSGHNRVVALTAGSATPVHLPFADLSFPAGVTVDRDDSVYVADLNNNRVLKLAAG 302 VY D+ RV+ L G +T LPF LS G+TVD +VYVAD N+V+KL A Sbjct 149 AVYTVDNTQ-RVLKLAPGRSTQQVLPFNGLSSVGGLTVDSAGNVYVADTGKNQVVKLVAA 207 Query 303 SNAQSQLPFTGLFSPTDVAVDNDGAVYVIDFYNRMLKLPTA 343 SN Q + F+ LF P DVAVD G VYV + + +++ A Sbjct 208 SNTQQVVGFSDLFYPGDVAVDPAGNVYVTEIWTDRVRVLAA 248 Score = 104 bits (259), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 76/176 (44%), Positives = 100/176 (57%), Gaps = 7/176 (3%) Query 92 PSPPSQVVVPID-LWNPDGVTVDLADAVYVADSGHKRLLKLPAGSNTPTTLPFTDTIGPG 150 P +Q V+P + L + G+TVD A VYVAD+G +++KL A SNT + F+D PG Sbjct 164 PGRSTQQVLPFNGLSSVGGLTVDSAGNVYVADTGKNQVVKLVAASNTQQVVGFSDLFYPG 223 Query 151 GVAVNSNRDVYVIDEDSHHVLKLAAGIEPPVELPFGS-LGDAH--GLAVDRSDSVYVVDY 207 VAV+ +VYV + + V LAA EL F L H +AVD + V+V D Sbjct 224 DVAVDPAGNVYVTEIWTDRVRVLAADSGRQRELSFDHDLYQIHVFAVAVDPAGDVFVTDN 283 Query 208 DNAK---VLKLPPGADTPTELPFVGLDHPYDVAVDGAGTVYVTDSGHNRVVALTAG 260 + V++L G+ P LPF LD P VAVD AG+VYV D+GHNRVV LT G Sbjct 284 FQGQGYWVVELAAGSRAPKVLPFSALDAPNGVAVDSAGSVYVADAGHNRVVKLTLG 339 Score = 102 bits (254), Expect = 8e-20, Method: Compositional matrix adjust. Identities = 62/131 (48%), Positives = 78/131 (60%), Gaps = 2/131 (1%) Query 214 KLPPGADTPTELPFVGLDHPYDVAVDGAGTVYVTDSGHNRVVALTAGSATPVHLPFADLS 273 + P + +PF GL HP +AVD A VYV D+G+NRV+ L S T +PFADL+ Sbjct 78 RAKPATPAASVVPFTGLSHPTGIAVDAARNVYVADTGNNRVLKLAPESGTQEVIPFADLN 137 Query 274 FPAGVTVDRDDSVYVADLNNNRVLKLAAGSNAQSQLPFTGLFSPTDVAVDNDGAVYVIDF 333 P GV VD D +VY D N RVLKLA G + Q LPF GL S + VD+ G VYV D Sbjct 138 RPFGVAVDADGAVYTVD-NTQRVLKLAPGRSTQQVLPFNGLSSVGGLTVDSAGNVYVADT 196 Query 334 -YNRMLKLPTA 343 N+++KL A Sbjct 197 GKNQVVKLVAA 207 >gi|226363603|ref|YP_002781385.1| serine/threonine protein kinase [Rhodococcus opacus B4] gi|226242092|dbj|BAH52440.1| serine/threonine protein kinase [Rhodococcus opacus B4] Length=599 Score = 150 bits (379), Expect = 3e-34, Method: Compositional matrix adjust. Identities = 103/255 (41%), Positives = 142/255 (56%), Gaps = 7/255 (2%) Query 89 PTTPSPPSQVVVPI-DLWNPDGVTVDLADAVYVADSGHKRLLKLPAGSNTPTTLPFTDTI 147 P S +QVV+P+ L P G+ V A +Y+ADS K++L++ AGS T LPFT Sbjct 347 PGEESADAQVVLPLTGLQGPAGLAVSAAGNLYIADSAAKQVLEVRAGSYEQTVLPFTGLE 406 Query 148 GPGGVAVNSNRDVYVIDEDSHHVLKLAAGIEPPVELPFGSLGDAHGLAVDRSDSVYVVDY 207 P GVAV+++ DVYV D ++ V L G + P +PFG L G+A+ S+YV D Sbjct 407 VPQGVAVSASGDVYVSDLVTNTVSMLHGGTQVP--MPFGGLNQPFGIALGPDGSLYVADT 464 Query 208 DNAKVLKLPPGADTPTELPFVGLDHPYDVAVDGAGTVYVTDSGHNRVVALTAGSATPVHL 267 N +VL L P +P + P+ VAV G +YV N+V+A A + L Sbjct 465 LNNRVLALRDITAAPVAVPLTVIG-PFAVAVGEQGDLYVGTP--NKVLAWNAATRAQSFL 521 Query 268 PFADLSFPAGVTVDRDDSVYVADLNNNRVLKLAAGSNAQSQLPFTGLFSPTDVAVDNDGA 327 PF D+ GV VD + +VY D N+NR+L+L GS+ Q LPFTGL P +AV + G Sbjct 522 PFTDVQGVGGVAVDEEGTVYAIDQNHNRILRLPTGSDEQEVLPFTGLDQPEGIAVSSRGD 581 Query 328 VYVIDFYN-RMLKLP 341 VYV D N R++ LP Sbjct 582 VYVADTDNSRVVMLP 596 Score = 95.5 bits (236), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 64/167 (39%), Positives = 91/167 (55%), Gaps = 4/167 (2%) Query 96 SQVVVPID-LWNPDGVTVDLADAVYVADSGHKRLLKLPAGSNTPTTLPFTDTIGPGGVAV 154 +QV +P L P G+ + ++YVAD+ + R+L L + P +P T IGP VAV Sbjct 436 TQVPMPFGGLNQPFGIALGPDGSLYVADTLNNRVLALRDITAAPVAVPLT-VIGPFAVAV 494 Query 155 NSNRDVYVIDEDSHHVLKLAAGIEPPVELPFGSLGDAHGLAVDRSDSVYVVDYDNAKVLK 214 D+YV + VL A LPF + G+AVD +VY +D ++ ++L+ Sbjct 495 GEQGDLYV--GTPNKVLAWNAATRAQSFLPFTDVQGVGGVAVDEEGTVYAIDQNHNRILR 552 Query 215 LPPGADTPTELPFVGLDHPYDVAVDGAGTVYVTDSGHNRVVALTAGS 261 LP G+D LPF GLD P +AV G VYV D+ ++RVV L AGS Sbjct 553 LPTGSDEQEVLPFTGLDQPEGIAVSSRGDVYVADTDNSRVVMLPAGS 599 >gi|111021257|ref|YP_704229.1| protein kinase [Rhodococcus jostii RHA1] gi|110820787|gb|ABG96071.1| probable protein kinase [Rhodococcus jostii RHA1] Length=602 Score = 145 bits (365), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 101/255 (40%), Positives = 142/255 (56%), Gaps = 7/255 (2%) Query 89 PTTPSPPSQVVVPI-DLWNPDGVTVDLADAVYVADSGHKRLLKLPAGSNTPTTLPFTDTI 147 P S +QVV+P+ L P G+TV +Y+ADS K++LK+ AG+ T LPFT Sbjct 350 PGEESTSAQVVLPLTGLQGPAGLTVSGTGDLYIADSAAKQVLKVSAGTYEQTVLPFTGLE 409 Query 148 GPGGVAVNSNRDVYVIDEDSHHVLKLAAGIEPPVELPFGSLGDAHGLAVDRSDSVYVVDY 207 P GVAV+++ DVYV D ++ V L + P LPF L G+A+ ++YV D Sbjct 410 VPQGVAVSASGDVYVSDLVTNTVTMLHGSTQVP--LPFAGLDQPFGIALGPDATLYVADT 467 Query 208 DNAKVLKLPPGADTPTELPFVGLDHPYDVAVDGAGTVYVTDSGHNRVVALTAGSATPVHL 267 N +V+ L P +P + P+ VAV G +YV N+V+A A + +L Sbjct 468 LNNRVMSLHDVTAAPVAVPLTVIG-PFAVAVSEHGDLYVGTP--NKVLAWNAATHAQSYL 524 Query 268 PFADLSFPAGVTVDRDDSVYVADLNNNRVLKLAAGSNAQSQLPFTGLFSPTDVAVDNDGA 327 PF DL GV VD + +VY D N+NR+L+LAAGS+ Q LPF+ L P +AV + G Sbjct 525 PFTDLQSVGGVAVDDEGTVYAIDQNHNRILRLAAGSDEQEVLPFSELDQPEGIAVSSRGD 584 Query 328 VYVIDFYN-RMLKLP 341 VYV D N R++ LP Sbjct 585 VYVADTDNSRVVMLP 599 >gi|336459649|gb|EGO38584.1| NHL repeat protein,protein kinase family protein [Mycobacterium avium subsp. paratuberculosis S397] Length=572 Score = 132 bits (332), Expect = 9e-29, Method: Compositional matrix adjust. Identities = 77/165 (47%), Positives = 102/165 (62%), Gaps = 5/165 (3%) Query 139 TTLPFTDT---IGPGGVAVNSNRDVYVIDEDSH-HVLKLAAGIEPPVELPFGSLGDAHGL 194 + LPF + PGGV ++ +VYV E + V+KLAAG LPF L GL Sbjct 407 SVLPFNGIDFRLSPGGVTLDGTGNVYVTSEGMYGRVVKLAAGSGATTVLPFNGLYQPQGL 466 Query 195 AVDRSDSVYVVDYDNAKVLKLPPGADTPTELPFVGLDHPYDVAVDGAGTVYVTDSGHNRV 254 AVD + +VYV D++N +VL + G+++ ELPF GL++P VAVD G VYV D G++RV Sbjct 467 AVDGAGTVYVADFNN-RVLSMAAGSNSQKELPFSGLNYPEGVAVDSQGGVYVADRGNSRV 525 Query 255 VALTAGSATPVHLPFADLSFPAGVTVDRDDSVYVADLNNNRVLKL 299 + L AGS LPF L+ P V VDRD SVYVAD ++RV+KL Sbjct 526 LKLAAGSQNQTVLPFTALNTPLAVAVDRDQSVYVADRGDDRVVKL 570 Score = 127 bits (319), Expect = 3e-27, Method: Compositional matrix adjust. Identities = 76/150 (51%), Positives = 99/150 (66%), Gaps = 3/150 (2%) Query 193 GLAVDRSDSVYVVDYDN-AKVLKLPPGADTPTELPFVGLDHPYDVAVDGAGTVYVTDSGH 251 G+ +D + +VYV +V+KL G+ T LPF GL P +AVDGAGTVYV D + Sbjct 422 GVTLDGTGNVYVTSEGMYGRVVKLAAGSGATTVLPFNGLYQPQGLAVDGAGTVYVADF-N 480 Query 252 NRVVALTAGSATPVHLPFADLSFPAGVTVDRDDSVYVADLNNNRVLKLAAGSNAQSQLPF 311 NRV+++ AGS + LPF+ L++P GV VD VYVAD N+RVLKLAAGS Q+ LPF Sbjct 481 NRVLSMAAGSNSQKELPFSGLNYPEGVAVDSQGGVYVADRGNSRVLKLAAGSQNQTVLPF 540 Query 312 TGLFSPTDVAVDNDGAVYVIDFY-NRMLKL 340 T L +P VAVD D +VYV D +R++KL Sbjct 541 TALNTPLAVAVDRDQSVYVADRGDDRVVKL 570 Score = 112 bits (279), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 75/166 (46%), Positives = 93/166 (57%), Gaps = 6/166 (3%) Query 97 QVVVP---IDL-WNPDGVTVDLADAVYVADSG-HKRLLKLPAGSNTPTTLPFTDTIGPGG 151 Q V+P ID +P GVT+D VYV G + R++KL AGS T LPF P G Sbjct 406 QSVLPFNGIDFRLSPGGVTLDGTGNVYVTSEGMYGRVVKLAAGSGATTVLPFNGLYQPQG 465 Query 152 VAVNSNRDVYVIDEDSHHVLKLAAGIEPPVELPFGSLGDAHGLAVDRSDSVYVVDYDNAK 211 +AV+ VYV D + + VL +AAG ELPF L G+AVD VYV D N++ Sbjct 466 LAVDGAGTVYVADFN-NRVLSMAAGSNSQKELPFSGLNYPEGVAVDSQGGVYVADRGNSR 524 Query 212 VLKLPPGADTPTELPFVGLDHPYDVAVDGAGTVYVTDSGHNRVVAL 257 VLKL G+ T LPF L+ P VAVD +VYV D G +RVV L Sbjct 525 VLKLAAGSQNQTVLPFTALNTPLAVAVDRDQSVYVADRGDDRVVKL 570 Score = 69.3 bits (168), Expect = 8e-10, Method: Compositional matrix adjust. Identities = 39/78 (50%), Positives = 50/78 (65%), Gaps = 4/78 (5%) Query 267 LPFADLSF---PAGVTVDRDDSVYV-ADLNNNRVLKLAAGSNAQSQLPFTGLFSPTDVAV 322 LPF + F P GVT+D +VYV ++ RV+KLAAGS A + LPF GL+ P +AV Sbjct 409 LPFNGIDFRLSPGGVTLDGTGNVYVTSEGMYGRVVKLAAGSGATTVLPFNGLYQPQGLAV 468 Query 323 DNDGAVYVIDFYNRMLKL 340 D G VYV DF NR+L + Sbjct 469 DGAGTVYVADFNNRVLSM 486 >gi|254383857|ref|ZP_04999204.1| serine/threonine-protein kinase pknD [Streptomyces sp. Mg1] gi|194342749|gb|EDX23715.1| serine/threonine-protein kinase pknD [Streptomyces sp. Mg1] Length=328 Score = 131 bits (329), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 81/226 (36%), Positives = 123/226 (55%), Gaps = 1/226 (0%) Query 97 QVVVPID-LWNPDGVTVDLADAVYVADSGHKRLLKLPAGSNTPTTLPFTDTIGPGGVAVN 155 Q VP D L P G+ D A +YV+D+G+ R++ LP + +P P G+A+ Sbjct 83 QTTVPFDGLVRPTGMAWDAAGRLYVSDTGNNRVVVLPPDGGEQSVVPTVGLSRPLGLAIG 142 Query 156 SNRDVYVIDEDSHHVLKLAAGIEPPVELPFGSLGDAHGLAVDRSDSVYVVDYDNAKVLKL 215 D+Y+ D + V+K++A +P L GLA++ +YV D+ N +V+K+ Sbjct 143 RTGDLYIADSFNDRVVKVSAAGGGQTTVPTTGLLHPWGLALEPDGDLYVSDFVNDRVVKV 202 Query 216 PPGADTPTELPFVGLDHPYDVAVDGAGTVYVTDSGHNRVVALTAGSATPVHLPFADLSFP 275 + +P VGL P +A++ AG +Y+ DSG+NRVV + AG +P LS P Sbjct 203 AADGSGQSTVPTVGLSQPTGLALNAAGDLYIADSGNNRVVKVPAGGGGQSTVPTTGLSDP 262 Query 276 AGVTVDRDDSVYVADLNNNRVLKLAAGSNAQSQLPFTGLFSPTDVA 321 G+ +D S+YVAD NNRV++L Q LPFTGL +PT +A Sbjct 263 LGLALDGSGSLYVADGFNNRVVRLRETGGGQVTLPFTGLNTPTGLA 308 Score = 128 bits (321), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 77/224 (35%), Positives = 127/224 (57%), Gaps = 1/224 (0%) Query 118 VYVADSGHKRLLKLPAGSNTPTTLPFTDTIGPGGVAVNSNRDVYVIDEDSHHVLKLAAGI 177 +YV+D G+ R++ LP+ TT+PF + P G+A ++ +YV D ++ V+ L Sbjct 63 LYVSDYGNNRVVALPSDGGDQTTVPFDGLVRPTGMAWDAAGRLYVSDTGNNRVVVLPPDG 122 Query 178 EPPVELPFGSLGDAHGLAVDRSDSVYVVDYDNAKVLKLPPGADTPTELPFVGLDHPYDVA 237 +P L GLA+ R+ +Y+ D N +V+K+ T +P GL HP+ +A Sbjct 123 GEQSVVPTVGLSRPLGLAIGRTGDLYIADSFNDRVVKVSAAGGGQTTVPTTGLLHPWGLA 182 Query 238 VDGAGTVYVTDSGHNRVVALTAGSATPVHLPFADLSFPAGVTVDRDDSVYVADLNNNRVL 297 ++ G +YV+D ++RVV + A + +P LS P G+ ++ +Y+AD NNRV+ Sbjct 183 LEPDGDLYVSDFVNDRVVKVAADGSGQSTVPTVGLSQPTGLALNAAGDLYIADSGNNRVV 242 Query 298 KLAAGSNAQSQLPFTGLFSPTDVAVDNDGAVYVID-FYNRMLKL 340 K+ AG QS +P TGL P +A+D G++YV D F NR+++L Sbjct 243 KVPAGGGGQSTVPTTGLSDPLGLALDGSGSLYVADGFNNRVVRL 286 Score = 65.9 bits (159), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 38/101 (38%), Positives = 56/101 (56%), Gaps = 1/101 (0%) Query 244 VYVTDSGHNRVVALTAGSATPVHLPFADLSFPAGVTVDRDDSVYVADLNNNRVLKLAAGS 303 +YV+D G+NRVVAL + +PF L P G+ D +YV+D NNRV+ L Sbjct 63 LYVSDYGNNRVVALPSDGGDQTTVPFDGLVRPTGMAWDAAGRLYVSDTGNNRVVVLPPDG 122 Query 304 NAQSQLPFTGLFSPTDVAVDNDGAVYVIDFYN-RMLKLPTA 343 QS +P GL P +A+ G +Y+ D +N R++K+ A Sbjct 123 GEQSVVPTVGLSRPLGLAIGRTGDLYIADSFNDRVVKVSAA 163 >gi|291442837|ref|ZP_06582227.1| serine/threonine-protein kinase [Streptomyces roseosporus NRRL 15998] gi|291345784|gb|EFE72688.1| serine/threonine-protein kinase [Streptomyces roseosporus NRRL 15998] Length=363 Score = 127 bits (320), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 79/235 (34%), Positives = 132/235 (57%), Gaps = 2/235 (0%) Query 95 PSQVVVPIDLWNPDGVTVDLADAVYVADSGHKRLLKLPAGSNTPTTLPFTDTIGPGGVAV 154 P+ V V L P G+ + + +YV+D+G+ R++++P + +P TD P G+A+ Sbjct 131 PAMVAV-TGLIRPTGMVLGPSGDLYVSDTGNNRVVRVPGDGGPQSVVPTTDLSRPIGLAL 189 Query 155 NSNRDVYVIDEDSHHVLKLAAGIEPPVELPFGSLGDAHGLAVDRSDSVYVVDYDNAKVLK 214 N++ D+Y+ D + V+K+ A V +P L +GLA+DR+ +++V D+ N +V+K Sbjct 190 NADGDLYIADSFNDRVVKVPADGSGQVTVPTTGLLHPNGLALDRAGNLFVADFVNDRVVK 249 Query 215 LPPGADTPTELPFVGLDHPYDVAVDGAGTVYVTDSGHNRVVALTAGSATPVHLPFADLSF 274 +P T +P GL P +A G ++V+DSG++RVV L AG +P L+ Sbjct 250 VPADGGPQTTVPTTGLSQPTGLAFGRGGDLFVSDSGNDRVVRLPAGGGPQRTVPAIGLNS 309 Query 275 PAGVTVDRDDSVYVADLNNNRVLKLAAGSNAQSQLPFTGLFSPTDVAVDNDGAVY 329 P G+ D ++YVAD NN+RV+KL Q +P GL +P +A+ + A Y Sbjct 310 PYGLAFDPAGALYVADFNNDRVVKLPV-RGGQRTVPVAGLRTPAGLAIPSGRAGY 363 Score = 120 bits (302), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 75/225 (34%), Positives = 119/225 (53%), Gaps = 1/225 (0%) Query 118 VYVADSGHKRLLKLPAGSNTPTTLPFTDTIGPGGVAVNSNRDVYVIDEDSHHVLKLAAGI 177 +Y++D +L+LP P + T I P G+ + + D+YV D ++ V+++ Sbjct 111 LYISDYSDNTVLRLPPRGGAPAMVAVTGLIRPTGMVLGPSGDLYVSDTGNNRVVRVPGDG 170 Query 178 EPPVELPFGSLGDAHGLAVDRSDSVYVVDYDNAKVLKLPPGADTPTELPFVGLDHPYDVA 237 P +P L GLA++ +Y+ D N +V+K+P +P GL HP +A Sbjct 171 GPQSVVPTTDLSRPIGLALNADGDLYIADSFNDRVVKVPADGSGQVTVPTTGLLHPNGLA 230 Query 238 VDGAGTVYVTDSGHNRVVALTAGSATPVHLPFADLSFPAGVTVDRDDSVYVADLNNNRVL 297 +D AG ++V D ++RVV + A +P LS P G+ R ++V+D N+RV+ Sbjct 231 LDRAGNLFVADFVNDRVVKVPADGGPQTTVPTTGLSQPTGLAFGRGGDLFVSDSGNDRVV 290 Query 298 KLAAGSNAQSQLPFTGLFSPTDVAVDNDGAVYVIDFYN-RMLKLP 341 +L AG Q +P GL SP +A D GA+YV DF N R++KLP Sbjct 291 RLPAGGGPQRTVPAIGLNSPYGLAFDPAGALYVADFNNDRVVKLP 335 Score = 57.8 bits (138), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 32/103 (32%), Positives = 54/103 (53%), Gaps = 1/103 (0%) Query 240 GAGTVYVTDSGHNRVVALTAGSATPVHLPFADLSFPAGVTVDRDDSVYVADLNNNRVLKL 299 G +Y++D N V+ L P + L P G+ + +YV+D NNRV+++ Sbjct 107 GGAPLYISDYSDNTVLRLPPRGGAPAMVAVTGLIRPTGMVLGPSGDLYVSDTGNNRVVRV 166 Query 300 AAGSNAQSQLPFTGLFSPTDVAVDNDGAVYVIDFYN-RMLKLP 341 QS +P T L P +A++ DG +Y+ D +N R++K+P Sbjct 167 PGDGGPQSVVPTTDLSRPIGLALNADGDLYIADSFNDRVVKVP 209 >gi|239985881|ref|ZP_04706545.1| hypothetical protein SrosN1_01107 [Streptomyces roseosporus NRRL 11379] Length=288 Score = 125 bits (315), Expect = 7e-27, Method: Compositional matrix adjust. Identities = 79/235 (34%), Positives = 132/235 (57%), Gaps = 2/235 (0%) Query 95 PSQVVVPIDLWNPDGVTVDLADAVYVADSGHKRLLKLPAGSNTPTTLPFTDTIGPGGVAV 154 P+ V V L P G+ + + +YV+D+G+ R++++P + +P TD P G+A+ Sbjct 56 PAMVAV-TGLIRPTGMVLGPSGDLYVSDTGNNRVVRVPGDGGPQSVVPTTDLSRPIGLAL 114 Query 155 NSNRDVYVIDEDSHHVLKLAAGIEPPVELPFGSLGDAHGLAVDRSDSVYVVDYDNAKVLK 214 N++ D+Y+ D + V+K+ A V +P L +GLA+DR+ +++V D+ N +V+K Sbjct 115 NADGDLYIADSFNDRVVKVPADGSGQVTVPTTGLLHPNGLALDRAGNLFVADFVNDRVVK 174 Query 215 LPPGADTPTELPFVGLDHPYDVAVDGAGTVYVTDSGHNRVVALTAGSATPVHLPFADLSF 274 +P T +P GL P +A G ++V+DSG++RVV L AG +P L+ Sbjct 175 VPADGGPQTTVPTTGLSQPTGLAFGRGGDLFVSDSGNDRVVRLPAGGGPQRTVPAIGLNS 234 Query 275 PAGVTVDRDDSVYVADLNNNRVLKLAAGSNAQSQLPFTGLFSPTDVAVDNDGAVY 329 P G+ D ++YVAD NN+RV+KL Q +P GL +P +A+ + A Y Sbjct 235 PYGLAFDPAGALYVADFNNDRVVKLPV-RGGQRTVPVAGLRTPAGLAIPSGRAGY 288 Score = 119 bits (298), Expect = 7e-25, Method: Compositional matrix adjust. Identities = 75/225 (34%), Positives = 119/225 (53%), Gaps = 1/225 (0%) Query 118 VYVADSGHKRLLKLPAGSNTPTTLPFTDTIGPGGVAVNSNRDVYVIDEDSHHVLKLAAGI 177 +Y++D +L+LP P + T I P G+ + + D+YV D ++ V+++ Sbjct 36 LYISDYSDNTVLRLPPRGGAPAMVAVTGLIRPTGMVLGPSGDLYVSDTGNNRVVRVPGDG 95 Query 178 EPPVELPFGSLGDAHGLAVDRSDSVYVVDYDNAKVLKLPPGADTPTELPFVGLDHPYDVA 237 P +P L GLA++ +Y+ D N +V+K+P +P GL HP +A Sbjct 96 GPQSVVPTTDLSRPIGLALNADGDLYIADSFNDRVVKVPADGSGQVTVPTTGLLHPNGLA 155 Query 238 VDGAGTVYVTDSGHNRVVALTAGSATPVHLPFADLSFPAGVTVDRDDSVYVADLNNNRVL 297 +D AG ++V D ++RVV + A +P LS P G+ R ++V+D N+RV+ Sbjct 156 LDRAGNLFVADFVNDRVVKVPADGGPQTTVPTTGLSQPTGLAFGRGGDLFVSDSGNDRVV 215 Query 298 KLAAGSNAQSQLPFTGLFSPTDVAVDNDGAVYVIDFYN-RMLKLP 341 +L AG Q +P GL SP +A D GA+YV DF N R++KLP Sbjct 216 RLPAGGGPQRTVPAIGLNSPYGLAFDPAGALYVADFNNDRVVKLP 260 Score = 56.6 bits (135), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 32/103 (32%), Positives = 54/103 (53%), Gaps = 1/103 (0%) Query 240 GAGTVYVTDSGHNRVVALTAGSATPVHLPFADLSFPAGVTVDRDDSVYVADLNNNRVLKL 299 G +Y++D N V+ L P + L P G+ + +YV+D NNRV+++ Sbjct 32 GGAPLYISDYSDNTVLRLPPRGGAPAMVAVTGLIRPTGMVLGPSGDLYVSDTGNNRVVRV 91 Query 300 AAGSNAQSQLPFTGLFSPTDVAVDNDGAVYVIDFYN-RMLKLP 341 QS +P T L P +A++ DG +Y+ D +N R++K+P Sbjct 92 PGDGGPQSVVPTTDLSRPIGLALNADGDLYIADSFNDRVVKVP 134 >gi|326780986|ref|ZP_08240251.1| NHL repeat containing protein [Streptomyces cf. griseus XylebKG-1] gi|326661319|gb|EGE46165.1| NHL repeat containing protein [Streptomyces griseus XylebKG-1] Length=326 Score = 122 bits (307), Expect = 7e-26, Method: Compositional matrix adjust. Identities = 75/225 (34%), Positives = 126/225 (56%), Gaps = 1/225 (0%) Query 118 VYVADSGHKRLLKLPAGSNTPTTLPFTDTIGPGGVAVNSNRDVYVIDEDSHHVLKLAAGI 177 +YV+D +L+LP G P T+ + P G+A++++ D+Y+ D ++ V+++ Sbjct 67 LYVSDYADNTVLRLPPGGGDPVTVAASGLTRPTGLALDASGDLYIADTGNNRVVRVPGDG 126 Query 178 EPPVELPFGSLGDAHGLAVDRSDSVYVVDYDNAKVLKLPPGADTPTELPFVGLDHPYDVA 237 P V + L GLA+ + +Y+ D N +V+ +P +P GL HP +A Sbjct 127 GPQVTVDTTGLFRPIGLALTANGDLYIADSFNDRVVMVPADGGGQVTVPTTGLLHPNGLA 186 Query 238 VDGAGTVYVTDSGHNRVVALTAGSATPVHLPFADLSFPAGVTVDRDDSVYVADLNNNRVL 297 +DGAG ++V D ++RVV + A +P LS P G+ DR +++V+D N+RV+ Sbjct 187 LDGAGNLFVADFVNDRVVEVPADGGPQTTVPTTGLSQPTGLAFDRRGNLFVSDSGNDRVV 246 Query 298 KLAAGSNAQSQLPFTGLFSPTDVAVDNDGAVYVIDFYN-RMLKLP 341 ++ AG Q +P TGL SP +A D GA+YV DF N R++++P Sbjct 247 EVPAGGGPQRTVPATGLDSPYGLAFDRSGALYVADFDNDRVVEVP 291 >gi|182440319|ref|YP_001828038.1| hypothetical protein SGR_6526 [Streptomyces griseus subsp. griseus NBRC 13350] gi|178468835|dbj|BAG23355.1| hypothetical protein [Streptomyces griseus subsp. griseus NBRC 13350] Length=302 Score = 122 bits (306), Expect = 9e-26, Method: Compositional matrix adjust. Identities = 74/225 (33%), Positives = 126/225 (56%), Gaps = 1/225 (0%) Query 118 VYVADSGHKRLLKLPAGSNTPTTLPFTDTIGPGGVAVNSNRDVYVIDEDSHHVLKLAAGI 177 +YV+D +L+LP G P T+ + P G+A++++ D+Y+ D ++ V+++ Sbjct 43 LYVSDYADNTVLRLPPGGGDPVTVAASGLTRPTGLALDASGDLYIADTGNNRVVRVPGDG 102 Query 178 EPPVELPFGSLGDAHGLAVDRSDSVYVVDYDNAKVLKLPPGADTPTELPFVGLDHPYDVA 237 P V + L GLA+ + +Y+ D N +V+ +P +P GL HP +A Sbjct 103 GPQVTVDTTGLSRPIGLALTANGDLYIADSVNDRVVMVPADGGGQVTVPTTGLLHPNGLA 162 Query 238 VDGAGTVYVTDSGHNRVVALTAGSATPVHLPFADLSFPAGVTVDRDDSVYVADLNNNRVL 297 +DGAG ++V D ++RVV + A +P LS P G+ DR +++V+D N+RV+ Sbjct 163 LDGAGNLFVADFVNDRVVKVPADGGPQTTVPTTGLSQPTGLAFDRRGNLFVSDSGNDRVV 222 Query 298 KLAAGSNAQSQLPFTGLFSPTDVAVDNDGAVYVIDFYN-RMLKLP 341 ++ AG + +P TGL SP +A D GA+YV DF N R++++P Sbjct 223 EVPAGGGPRRTVPATGLDSPYGLAFDRSGALYVADFDNDRVVEVP 267 Score = 115 bits (288), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 71/219 (33%), Positives = 121/219 (56%), Gaps = 1/219 (0%) Query 104 LWNPDGVTVDLADAVYVADSGHKRLLKLPAGSNTPTTLPFTDTIGPGGVAVNSNRDVYVI 163 L P G+ +D + +Y+AD+G+ R++++P T+ T P G+A+ +N D+Y+ Sbjct 71 LTRPTGLALDASGDLYIADTGNNRVVRVPGDGGPQVTVDTTGLSRPIGLALTANGDLYIA 130 Query 164 DEDSHHVLKLAAGIEPPVELPFGSLGDAHGLAVDRSDSVYVVDYDNAKVLKLPPGADTPT 223 D + V+ + A V +P L +GLA+D + +++V D+ N +V+K+P T Sbjct 131 DSVNDRVVMVPADGGGQVTVPTTGLLHPNGLALDGAGNLFVADFVNDRVVKVPADGGPQT 190 Query 224 ELPFVGLDHPYDVAVDGAGTVYVTDSGHNRVVALTAGSATPVHLPFADLSFPAGVTVDRD 283 +P GL P +A D G ++V+DSG++RVV + AG +P L P G+ DR Sbjct 191 TVPTTGLSQPTGLAFDRRGNLFVSDSGNDRVVEVPAGGGPRRTVPATGLDSPYGLAFDRS 250 Query 284 DSVYVADLNNNRVLKLAAGSNAQSQLPFTGLFSPTDVAV 322 ++YVAD +N+RV+++ LP GL +P +AV Sbjct 251 GALYVADFDNDRVVEVPV-RGGLRPLPVAGLRTPAGLAV 288 Score = 94.7 bits (234), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 53/145 (37%), Positives = 83/145 (58%), Gaps = 1/145 (0%) Query 198 RSDSVYVVDYDNAKVLKLPPGADTPTELPFVGLDHPYDVAVDGAGTVYVTDSGHNRVVAL 257 R+ +YV DY + VL+LPPG P + GL P +A+D +G +Y+ D+G+NRVV + Sbjct 39 RAAPLYVSDYADNTVLRLPPGGGDPVTVAASGLTRPTGLALDASGDLYIADTGNNRVVRV 98 Query 258 TAGSATPVHLPFADLSFPAGVTVDRDDSVYVADLNNNRVLKLAAGSNAQSQLPFTGLFSP 317 V + LS P G+ + + +Y+AD N+RV+ + A Q +P TGL P Sbjct 99 PGDGGPQVTVDTTGLSRPIGLALTANGDLYIADSVNDRVVMVPADGGGQVTVPTTGLLHP 158 Query 318 TDVAVDNDGAVYVIDFYN-RMLKLP 341 +A+D G ++V DF N R++K+P Sbjct 159 NGLALDGAGNLFVADFVNDRVVKVP 183 >gi|219852087|ref|YP_002466519.1| NHL repeat containing protein [Methanosphaerula palustris E1-9c] gi|219546346|gb|ACL16796.1| NHL repeat containing protein [Methanosphaerula palustris E1-9c] Length=668 Score = 112 bits (281), Expect = 6e-23, Method: Compositional matrix adjust. Identities = 87/265 (33%), Positives = 124/265 (47%), Gaps = 32/265 (12%) Query 107 PDGVTVDLADAVYVADSGHKRLLKLPA--------GSNTPTTLPFTDTIGPGGVAVNSNR 158 P+G+ +D VYV D+ + R+ + + GS+ F P G+A++SN Sbjct 189 PNGIAIDSTGNVYVTDAYNNRIQEFNSTGGYLMQWGSSGSEAGQFEI---PQGIAMDSND 245 Query 159 DVYVIDEDSHHVLKLAAGIEPPVEL-----PFGSLGDAHGLAVDRSDSVYVVDYDNAKVL 213 +VYV D + V K + + G + G+AVD +D+VY+ D N +V Sbjct 246 NVYVADS-GNRVQKFTSAGTFITQWGTKGSEAGQFSNPFGIAVDSADNVYITDVYNNRVQ 304 Query 214 KLPPGADTPTELPFVGLD-----HPYDVAVDGAGTVYVTDSGHNRVVALTAGSATPVHLP 268 K T+ GL+ PY AVD AG VYVTD G++RV TA Sbjct 305 KFTSAGTFITQWGSQGLEVGQFNMPYGDAVDSAGNVYVTDLGNSRVQKFTANGTFITEWG 364 Query 269 FA-----DLSFPAGVTVDRDDSVYVADLNNNRVLKLAAGSNAQSQLPFTG-----LFSPT 318 + + P G+ VD D+VYVADLNNNRV K + + +Q TG P Sbjct 365 SSGSGDGQFNMPYGIAVDSADNVYVADLNNNRVQKFNSTGSYLTQWGMTGSGNGQFDQPC 424 Query 319 DVAVDNDGAVYVIDFYNRMLKLPTA 343 VAVD G VYV DF N +++ T+ Sbjct 425 GVAVDRFGIVYVTDFGNNRVQMFTS 449 Score = 107 bits (266), Expect = 4e-21, Method: Compositional matrix adjust. Identities = 90/259 (35%), Positives = 117/259 (46%), Gaps = 25/259 (9%) Query 106 NPDGVTVDLADAVYVADSGHKRLLKLPAGSNTPTT-----LPFTDTIGPGGVAVNSNRDV 160 NP G+ VD AD VY+ D + R+ K + T L P G AV+S +V Sbjct 281 NPFGIAVDSADNVYITDVYNNRVQKFTSAGTFITQWGSQGLEVGQFNMPYGDAVDSAGNV 340 Query 161 YVIDEDSHHVLKLAAGIEPPVELPFGSLGDA-----HGLAVDRSDSVYVVDYDNAKVLKL 215 YV D + V K A E GD +G+AVD +D+VYV D +N +V K Sbjct 341 YVTDLGNSRVQKFTANGTFITEWGSSGSGDGQFNMPYGIAVDSADNVYVADLNNNRVQKF 400 Query 216 PPGADTPTELPFVG-----LDHPYDVAVDGAGTVYVTDSGHNRVVALTAG----SATPVH 266 T+ G D P VAVD G VYVTD G+NRV T+ S H Sbjct 401 NSTGSYLTQWGMTGSGNGQFDQPCGVAVDRFGIVYVTDFGNNRVQMFTSAGGYLSQWGSH 460 Query 267 LPFA-DLSFPAGVTVDRDDSVYVADLNNNRVLKLAAGSNAQSQLPFTG----LFS-PTDV 320 P A S P G+ +D +VY+ D NNRV K + + Q +G +F T V Sbjct 461 GPGAGQFSGPNGIALDSTGNVYITDWGNNRVQKFTSTGSYLRQWGSSGSEDGMFGDSTSV 520 Query 321 AVDNDGAVYVIDFYNRMLK 339 AVD D VYV D N ++ Sbjct 521 AVDRDSNVYVSDSSNHRIQ 539 Score = 81.6 bits (200), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 70/221 (32%), Positives = 99/221 (45%), Gaps = 43/221 (19%) Query 107 PDGVTVDLADAVYVADSGHKRLLKLPA--------GSNTPTTLPFTDTIGPGGVAVNSNR 158 P GV VD VYV D G+ R+ + GS+ P F+ GP G+A++S Sbjct 423 PCGVAVDRFGIVYVTDFGNNRVQMFTSAGGYLSQWGSHGPGAGQFS---GPNGIALDSTG 479 Query 159 DVYVIDEDSHHVLKL-----------AAGIEPPVELPFGSLGDAHGLAVDRSDSVYVVDY 207 +VY+ D ++ V K ++G E G GD+ +AVDR +VYV D Sbjct 480 NVYITDWGNNRVQKFTSTGSYLRQWGSSGSED------GMFGDSTSVAVDRDSNVYVSDS 533 Query 208 DNAKVLKLPPGADTPTELPFVGLD-----HPYDVAVDGAGTVYVTDSGHNRVVALTAGSA 262 N ++ K T+ GL+ P+ + VDGAG VYVTD NRV+ Sbjct 534 SNHRIQKFDQNGTFITKWGSYGLEAGQFNSPFGITVDGAGNVYVTDVNSNRVLKFAPTGT 593 Query 263 TPVHLPFADLSFPAGVTVDRD---DSVYVADLNNNRVLKLA 300 TPV + P G V +D D +Y D++ N VL Sbjct 594 TPVVIV------PGGSAVPQDLNHDGLY-EDVDGNGVLDFG 627 Score = 78.6 bits (192), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 65/217 (30%), Positives = 96/217 (45%), Gaps = 24/217 (11%) Query 149 PGGVAVNSNRDVYVIDEDSHHVLKLAAGIEPPVELPFGSLGDAHG-------LAVDRSDS 201 P GV ++S DVYV+D ++ + K + +GS G G +AVD Sbjct 48 PYGVTIDSIGDVYVVDTYNNWIQKFDS--NGTFLKKWGSFGTGDGQFNIPYDIAVDSVGY 105 Query 202 VYVVDYDNAKVLKLPPGADTPTELPFVG-----LDHPYDVAVDGAGTVYVTDSGHNRVVA 256 VYV D +N ++ K T+ G LD P VAVD G +YV D G+NRV Sbjct 106 VYVADMNNNRIQKFNSTGGYLTQWGTKGSEEGQLDQPGSVAVDSRGQIYVADWGNNRVQV 165 Query 257 LTAGSATPVHLPFA---DLSF--PAGVTVDRDDSVYVADLNNNRVLKLAAGSNAQSQLPF 311 + + + D F P G+ +D +VYV D NNR+ + + Q Sbjct 166 FNSTGGYLMQWGSSGSGDGQFDGPNGIAIDSTGNVYVTDAYNNRIQEFNSTGGYLMQWGS 225 Query 312 TG-----LFSPTDVAVDNDGAVYVIDFYNRMLKLPTA 343 +G P +A+D++ VYV D NR+ K +A Sbjct 226 SGSEAGQFEIPQGIAMDSNDNVYVADSGNRVQKFTSA 262 Score = 77.4 bits (189), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 73/268 (28%), Positives = 113/268 (43%), Gaps = 37/268 (13%) Query 107 PDGVTVDLADAVYVADSGHKRLLKLPAGSNTPTTLPFTDTIGPG--------GVAVNSNR 158 P GVT+D VYV D+ + + K + T L + G G +AV+S Sbjct 48 PYGVTIDSIGDVYVVDTYNNWIQKFDS---NGTFLKKWGSFGTGDGQFNIPYDIAVDSVG 104 Query 159 DVYVIDEDSHHVLKLAAGIEPPVELPFGSLGDAHG-------LAVDRSDSVYVVDYDNAK 211 VYV D +++ + K + +G+ G G +AVD +YV D+ N + Sbjct 105 YVYVADMNNNRIQKFNS--TGGYLTQWGTKGSEEGQLDQPGSVAVDSRGQIYVADWGNNR 162 Query 212 VLKLPPGADTPTELPFVG-----LDHPYDVAVDGAGTVYVTDSGHNRVVALTAGSATPVH 266 V + G D P +A+D G VYVTD+ +NR+ + + Sbjct 163 VQVFNSTGGYLMQWGSSGSGDGQFDGPNGIAIDSTGNVYVTDAYNNRIQEFNSTGGYLMQ 222 Query 267 L-----PFADLSFPAGVTVDRDDSVYVADLNNNRVLKLAAGSNAQSQLPFTG-----LFS 316 P G+ +D +D+VYVAD + NRV K + +Q G + Sbjct 223 WGSSGSEAGQFEIPQGIAMDSNDNVYVAD-SGNRVQKFTSAGTFITQWGTKGSEAGQFSN 281 Query 317 PTDVAVDNDGAVYVIDFY-NRMLKLPTA 343 P +AVD+ VY+ D Y NR+ K +A Sbjct 282 PFGIAVDSADNVYITDVYNNRVQKFTSA 309 Score = 73.6 bits (179), Expect = 4e-11, Method: Compositional matrix adjust. Identities = 68/220 (31%), Positives = 96/220 (44%), Gaps = 32/220 (14%) Query 107 PDGVTVDLADAVYVADSGHKRLLKLPAGSNTPTTLPFTDTIG-----PGGVAVNSNRDVY 161 P G+ VD AD VYVAD + R+ K + + T T + P GVAV+ VY Sbjct 376 PYGIAVDSADNVYVADLNNNRVQKFNSTGSYLTQWGMTGSGNGQFDQPCGVAVDRFGIVY 435 Query 162 VIDEDSHHVLKLAA--------GIEPPVELPFGSLGDAHGLAVDRSDSVYVVDYDNAKVL 213 V D ++ V + G P G +G+A+D + +VY+ D+ N +V Sbjct 436 VTDFGNNRVQMFTSAGGYLSQWGSHGPGA---GQFSGPNGIALDSTGNVYITDWGNNRVQ 492 Query 214 KLPPGADTPTELPFVGLDHPYD--------VAVDGAGTVYVTDSGHNRVVALTAGSA--- 262 K T + L G D VAVD VYV+DS ++R+ Sbjct 493 KFTS---TGSYLRQWGSSGSEDGMFGDSTSVAVDRDSNVYVSDSSNHRIQKFDQNGTFIT 549 Query 263 --TPVHLPFADLSFPAGVTVDRDDSVYVADLNNNRVLKLA 300 L + P G+TVD +VYV D+N+NRVLK A Sbjct 550 KWGSYGLEAGQFNSPFGITVDGAGNVYVTDVNSNRVLKFA 589 Score = 68.9 bits (167), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 54/172 (32%), Positives = 73/172 (43%), Gaps = 21/172 (12%) Query 186 GSLGDAHGLAVDRSDSVYVVDYDNAKVLKLPPGADTPTELPFVG-----LDHPYDVAVDG 240 G +G+ +D VYVVD N + K + G + PYD+AVD Sbjct 43 GQFNQPYGVTIDSIGDVYVVDTYNNWIQKFDSNGTFLKKWGSFGTGDGQFNIPYDIAVDS 102 Query 241 AGTVYVTDSGHNRVVAL--TAGSATPVHLPFAD---LSFPAGVTVDRDDSVYVADLNNNR 295 G VYV D +NR+ T G T ++ L P V VD +YVAD NNR Sbjct 103 VGYVYVADMNNNRIQKFNSTGGYLTQWGTKGSEEGQLDQPGSVAVDSRGQIYVADWGNNR 162 Query 296 V--------LKLAAGSNAQSQLPFTGLFSPTDVAVDNDGAVYVIDFYNRMLK 339 V + GS+ F G P +A+D+ G VYV D YN ++ Sbjct 163 VQVFNSTGGYLMQWGSSGSGDGQFDG---PNGIAIDSTGNVYVTDAYNNRIQ 211 Score = 55.5 bits (132), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 38/121 (32%), Positives = 57/121 (48%), Gaps = 10/121 (8%) Query 230 LDHPYDVAVDGAGTVYVTDSGHNRVVAL-TAGSATPVHLPFA----DLSFPAGVTVDRDD 284 + PY V +D G VYV D+ +N + + G+ F + P + VD Sbjct 45 FNQPYGVTIDSIGDVYVVDTYNNWIQKFDSNGTFLKKWGSFGTGDGQFNIPYDIAVDSVG 104 Query 285 SVYVADLNNNRVLKLAAGSNAQSQLPFTG-----LFSPTDVAVDNDGAVYVIDFYNRMLK 339 VYVAD+NNNR+ K + +Q G L P VAVD+ G +YV D+ N ++ Sbjct 105 YVYVADMNNNRIQKFNSTGGYLTQWGTKGSEEGQLDQPGSVAVDSRGQIYVADWGNNRVQ 164 Query 340 L 340 + Sbjct 165 V 165 >gi|322435783|ref|YP_004217995.1| cell surface receptor IPT/TIG [Acidobacterium sp. MP5ACTX9] gi|321163510|gb|ADW69215.1| cell surface receptor IPT/TIG domain protein [Acidobacterium sp. MP5ACTX9] Length=1852 Score = 108 bits (271), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 87/258 (34%), Positives = 131/258 (51%), Gaps = 14/258 (5%) Query 100 VPIDLWNPDGVTVDLADAVYVADSGHKRLLKLPAGSNTPTTLPFTDTI-GPGGVAVNSNR 158 +P P + +D A Y+A+ G+ +LK+P G T + +T GP VAV+ Sbjct 156 LPGTYSQPRSIALDGAGNAYIANFGNANVLKVPVGCTTSACVTTLETFSGPASVAVDGAG 215 Query 159 DVYVIDEDSHHVLK-LAAGIEPPVELPFGSLGDAHGLAVDRSDSVYVVDYDNAKVLKLPP 217 +VYV D + + VLK LA V G + G+AVD S +V+V D+ N +V + P Sbjct 216 NVYVADFNLNEVLKILANCTSECVSTLGGGFNEPIGIAVDGSGNVFVADFANNQVKVIAP 275 Query 218 GADTPTELPFV--GLDHPYDVAVDGAGTVYVTDSGHNRVVALTAGSATPVHLPFADL--- 272 G + + + + G +P D+AVD +GTVY+ D G++ V ++ A + V L Sbjct 276 GCTSASCVEPLGNGFSNPQDIAVDASGTVYIADYGNSLVKSMPANCNSFVGCTITTLGGG 335 Query 273 -SFPAGVTVDRDDSVYVADLNNNRVLKLAAG---SNAQSQL-PFTGLFS-PTDVAVDNDG 326 S P+GV VD + +VYV D NN V + G +NA + + G S P V +D G Sbjct 336 FSSPSGVAVDGNGNVYVGDSGNNAVEVMTPGCTPANASTCVTTLNGTLSGPIGVTLDGGG 395 Query 327 AVYVIDFYNRMLK-LPTA 343 VYV D N ++ LP A Sbjct 396 NVYVADNGNNAIRELPRA 413 Score = 92.0 bits (227), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 78/222 (36%), Positives = 110/222 (50%), Gaps = 23/222 (10%) Query 96 SQVVVPIDLWN-PDGVTVDLADAVYVADSGHKRLLKLPAGSNTPTTLPFTDTIGPG---- 150 S V ++ ++ P V VD A VYVAD +LK+ A T T+G G Sbjct 194 SACVTTLETFSGPASVAVDGAGNVYVADFNLNEVLKILANC----TSECVSTLGGGFNEP 249 Query 151 -GVAVNSNRDVYVIDEDSHHVLKLAAGIEPP--VELPFGS-LGDAHGLAVDRSDSVYVVD 206 G+AV+ + +V+V D ++ V +A G VE P G+ + +AVD S +VY+ D Sbjct 250 IGIAVDGSGNVFVADFANNQVKVIAPGCTSASCVE-PLGNGFSNPQDIAVDASGTVYIAD 308 Query 207 YDNAKVLKLPPGADTPTELPFV----GLDHPYDVAVDGAGTVYVTDSGHNRVVALTAG-- 260 Y N+ V +P ++ G P VAVDG G VYV DSG+N V +T G Sbjct 309 YGNSLVKSMPANCNSFVGCTITTLGGGFSSPSGVAVDGNGNVYVGDSGNNAVEVMTPGCT 368 Query 261 ---SATPVHLPFADLSFPAGVTVDRDDSVYVADLNNNRVLKL 299 ++T V LS P GVT+D +VYVAD NN + +L Sbjct 369 PANASTCVTTLNGTLSGPIGVTLDGGGNVYVADNGNNAIREL 410 Score = 81.6 bits (200), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 71/210 (34%), Positives = 101/210 (49%), Gaps = 15/210 (7%) Query 104 LWNPDGVTVDLADAVYVADSGHKRLLKLPA-GSNTPTTLPFTDTIGPG------GVAVNS 156 +P GV VD A VYVAD GH L ++ A G + PT+ P T+GPG GV V+ Sbjct 1200 FASPTGVAVDGAGNVYVADFGHGALKEMRAVGGSVPTSNPQIATLGPGKFIAPLGVTVDG 1259 Query 157 NRDVYVIDEDSHHVLKLAAGIEPPVELPFGSLGDAHGLAVDRSDSVYVVDYDNAKVLKLP 216 +VY+ D + V ++ A L + + HG+AVD +V+V D+ N V ++ Sbjct 1260 AGNVYLTDAQAGTVWEIVASTGSVNALGT-TFSNPHGIAVDAFGNVFVADFGNNAVKEI- 1317 Query 217 PGADTPTELPFVGLDHPYDVAVDGAGTVYVTDSGHNRVVALTAG-----SATPVHLPFA- 270 GA P VA+D AG VYV D+ V + A S++P L Sbjct 1318 VGASGAIVTVGPAFTTPNWVAIDAAGDVYVADAATGTVSEMVAVNGSIPSSSPTVLTLGP 1377 Query 271 DLSFPAGVTVDRDDSVYVADLNNNRVLKLA 300 + P G+ +D +VY+AD N V KLA Sbjct 1378 GFTSPTGLALDEAGNVYIADNGPNTVYKLA 1407 Score = 70.1 bits (170), Expect = 5e-10, Method: Compositional matrix adjust. Identities = 56/155 (37%), Positives = 77/155 (50%), Gaps = 9/155 (5%) Query 192 HGLAVDRSDSVYVVDYDNAKVLKLPPGADTPTELPFVGLDHPYDVAVDGAGTVYVTDSGH 251 + +AVD + +VYV D+ N V ++ AD G P VAVDGAG VYV D GH Sbjct 1163 YSMAVDAAGNVYVADFKNNAVKEILA-ADGSVLTLGSGFASPTGVAVDGAGNVYVADFGH 1221 Query 252 NRVVALTA-GSATPVHLP-FADLS-----FPAGVTVDRDDSVYVADLNNNRVLKLAAGSN 304 + + A G + P P A L P GVTVD +VY+ D V ++ A + Sbjct 1222 GALKEMRAVGGSVPTSNPQIATLGPGKFIAPLGVTVDGAGNVYLTDAQAGTVWEIVASTG 1281 Query 305 AQSQLPFTGLFSPTDVAVDNDGAVYVIDFYNRMLK 339 + + L T +P +AVD G V+V DF N +K Sbjct 1282 SVNALGTT-FSNPHGIAVDAFGNVFVADFGNNAVK 1315 Score = 67.4 bits (163), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 66/219 (31%), Positives = 103/219 (48%), Gaps = 29/219 (13%) Query 125 HKRLLKLPAGSNTPTTLPFTDTIGPGGVAVNSNRDVYVIDEDSHHVLKLAAGIEPPVELP 184 ++ L L +G N P ++ AV++ +VYV D ++ V ++ A + L Sbjct 1149 NQSLAILGSGFNQPYSM-----------AVDAAGNVYVADFKNNAVKEILAADGSVLTLG 1197 Query 185 FGSLGDAHGLAVDRSDSVYVVDYDNAKVLKL-PPGADTPTELPFVG------LDHPYDVA 237 G G+AVD + +VYV D+ + + ++ G PT P + P V Sbjct 1198 SG-FASPTGVAVDGAGNVYVADFGHGALKEMRAVGGSVPTSNPQIATLGPGKFIAPLGVT 1256 Query 238 VDGAGTVYVTDSGHNRV--VALTAGSATPVHLPFADLSFPAGVTVDRDDSVYVADLNNNR 295 VDGAG VY+TD+ V + + GS + F++ P G+ VD +V+VAD NN Sbjct 1257 VDGAGNVYLTDAQAGTVWEIVASTGSVNALGTTFSN---PHGIAVDAFGNVFVADFGNNA 1313 Query 296 VLKLAAGSNAQSQL--PFTGLFSPTDVAVDNDGAVYVID 332 V ++ S A + FT +P VA+D G VYV D Sbjct 1314 VKEIVGASGAIVTVGPAFT---TPNWVAIDAAGDVYVAD 1349 Score = 65.9 bits (159), Expect = 8e-09, Method: Compositional matrix adjust. Identities = 80/270 (30%), Positives = 117/270 (44%), Gaps = 25/270 (9%) Query 92 PSPPSQVVVPIDLWNPDGVTVDLADAVYVADSGHKRLLKLPAGSNTPTTLPFTDTIGPGG 151 P+ S ++ P + VD A VYVAD + + ++ A + TL + P G Sbjct 1147 PTNQSLAILGSGFNQPYSMAVDAAGNVYVADFKNNAVKEILAADGSVLTLG-SGFASPTG 1205 Query 152 VAVNSNRDVYVIDEDSHHVLKL--AAGIEPPVELP-FGSLGDAH-----GLAVDRSDSVY 203 VAV+ +VYV D H LK A G P P +LG G+ VD + +VY Sbjct 1206 VAVDGAGNVYVADFG-HGALKEMRAVGGSVPTSNPQIATLGPGKFIAPLGVTVDGAGNVY 1264 Query 204 VVDYDNAKVLKLPPGADTPTELPFVGLDHPYDVAVDGAGTVYVTDSGHNRVVALTAGSAT 263 + D V ++ + L +P+ +AVD G V+V D G+N V + S Sbjct 1265 LTDAQAGTVWEIVASTGSVNALGTT-FSNPHGIAVDAFGNVFVADFGNNAVKEIVGASGA 1323 Query 264 PVHLPFADLSFPAGVTVDRDDSVYVADLNNNRVLKLAAGSNAQSQLPFT---------GL 314 V + A + P V +D VYVAD V ++ A +P + G Sbjct 1324 IVTVGPA-FTTPNWVAIDAAGDVYVADAATGTVSEMVA---VNGSIPSSSPTVLTLGPGF 1379 Query 315 FSPTDVAVDNDGAVYVIDFY-NRMLKLPTA 343 SPT +A+D G VY+ D N + KL TA Sbjct 1380 TSPTGLALDEAGNVYIADNGPNTVYKLATA 1409 Score = 56.6 bits (135), Expect = 6e-06, Method: Compositional matrix adjust. Identities = 50/175 (29%), Positives = 84/175 (48%), Gaps = 17/175 (9%) Query 107 PDGVTVDLADAVYVADSGHKRLLKLPAGSNTPTTLP-----FTDTIGPGGVAVNSNRDVY 161 P G+ VD + V+VAD + ++ + G + + + F++ P +AV+++ VY Sbjct 249 PIGIAVDGSGNVFVADFANNQVKVIAPGCTSASCVEPLGNGFSN---PQDIAVDASGTVY 305 Query 162 VIDEDSHHVLKLAAGIEPPVELPFGSLGDA----HGLAVDRSDSVYVVDYDNAKVLKLPP 217 + D + V + A V +LG G+AVD + +VYV D N V + P Sbjct 306 IADYGNSLVKSMPANCNSFVGCTITTLGGGFSSPSGVAVDGNGNVYVGDSGNNAVEVMTP 365 Query 218 G---ADTPTELPFVG--LDHPYDVAVDGAGTVYVTDSGHNRVVALTAGSATPVHL 267 G A+ T + + L P V +DG G VYV D+G+N + L +A P++ Sbjct 366 GCTPANASTCVTTLNGTLSGPIGVTLDGGGNVYVADNGNNAIRELPRATAAPLNF 420 Score = 38.1 bits (87), Expect = 2.0, Method: Compositional matrix adjust. Identities = 32/119 (27%), Positives = 57/119 (48%), Gaps = 11/119 (9%) Query 107 PDGVTVDLADAVYVADSGHKRLLKLPA-GSNTPTTLPFTDTIGPG-----GVAVNSNRDV 160 P+ V +D A VYVAD+ + ++ A + P++ P T+GPG G+A++ +V Sbjct 1334 PNWVAIDAAGDVYVADAATGTVSEMVAVNGSIPSSSPTVLTLGPGFTSPTGLALDEAGNV 1393 Query 161 YVIDEDSHHVLKLAAGIEPPVELPFGSLGDAHGLAVDRSDSVYVVDYDNAKVLKLPPGA 219 Y+ D + V KLA P S+G + + S + ++ N ++ PG+ Sbjct 1394 YIADNGPNTVYKLATATPPSFTFAATSVG-----STSAAQSFSLQNFGNEDLVLSVPGS 1447 >gi|111025317|ref|YP_707737.1| hypothetical protein RHA1_ro08535 [Rhodococcus jostii RHA1] gi|110824296|gb|ABG99579.1| conserved hypothetical protein [Rhodococcus jostii RHA1] Length=101 Score = 108 bits (270), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 59/102 (58%), Positives = 70/102 (69%), Gaps = 2/102 (1%) Query 212 VLKLPPGADTPTELPFVGLDHPYDVAVDGAGTVYVTDSGHNRVVALTAGSATPVHLPFAD 271 +LKL G+ T TEL F GL +P+ VAVD AG VY D +NRV+ L AGS TP LPF Sbjct 1 MLKLAAGSSTQTEL-FTGLSYPWGVAVDTAGNVYAADW-NNRVLKLAAGSTTPTELPFTG 58 Query 272 LSFPAGVTVDRDDSVYVADLNNNRVLKLAAGSNAQSQLPFTG 313 L +P GV VD +VYVAD N RVLKLAAGS+ ++LPFTG Sbjct 59 LHYPEGVAVDTAGAVYVADWRNLRVLKLAAGSSTPTELPFTG 100 Score = 94.4 bits (233), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 54/100 (54%), Positives = 66/100 (66%), Gaps = 2/100 (2%) Query 170 VLKLAAGIEPPVELPFGSLGDAHGLAVDRSDSVYVVDYDNAKVLKLPPGADTPTELPFVG 229 +LKLAAG EL F L G+AVD + +VY D++N +VLKL G+ TPTELPF G Sbjct 1 MLKLAAGSSTQTEL-FTGLSYPWGVAVDTAGNVYAADWNN-RVLKLAAGSTTPTELPFTG 58 Query 230 LDHPYDVAVDGAGTVYVTDSGHNRVVALTAGSATPVHLPF 269 L +P VAVD AG VYV D + RV+ L AGS+TP LPF Sbjct 59 LHYPEGVAVDTAGAVYVADWRNLRVLKLAAGSSTPTELPF 98 Score = 92.4 bits (228), Expect = 9e-17, Method: Compositional matrix adjust. Identities = 54/102 (53%), Positives = 67/102 (66%), Gaps = 2/102 (1%) Query 128 LLKLPAGSNTPTTLPFTDTIGPGGVAVNSNRDVYVIDEDSHHVLKLAAGIEPPVELPFGS 187 +LKL AGS+T T L FT P GVAV++ +VY D + + VLKLAAG P ELPF Sbjct 1 MLKLAAGSSTQTEL-FTGLSYPWGVAVDTAGNVYAADWN-NRVLKLAAGSTTPTELPFTG 58 Query 188 LGDAHGLAVDRSDSVYVVDYDNAKVLKLPPGADTPTELPFVG 229 L G+AVD + +VYV D+ N +VLKL G+ TPTELPF G Sbjct 59 LHYPEGVAVDTAGAVYVADWRNLRVLKLAAGSSTPTELPFTG 100 Score = 85.9 bits (211), Expect = 9e-15, Method: Compositional matrix adjust. Identities = 51/88 (58%), Positives = 60/88 (69%), Gaps = 3/88 (3%) Query 254 VVALTAGSATPVHLPFADLSFPAGVTVDRDDSVYVADLNNNRVLKLAAGSNAQSQLPFTG 313 ++ L AGS+T L F LS+P GV VD +VY AD NN RVLKLAAGS ++LPFTG Sbjct 1 MLKLAAGSSTQTEL-FTGLSYPWGVAVDTAGNVYAADWNN-RVLKLAAGSTTPTELPFTG 58 Query 314 LFSPTDVAVDNDGAVYVIDFYN-RMLKL 340 L P VAVD GAVYV D+ N R+LKL Sbjct 59 LHYPEGVAVDTAGAVYVADWRNLRVLKL 86 Score = 75.1 bits (183), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 45/79 (57%), Positives = 50/79 (64%), Gaps = 1/79 (1%) Query 107 PDGVTVDLADAVYVADSGHKRLLKLPAGSNTPTTLPFTDTIGPGGVAVNSNRDVYVIDED 166 P GV VD A VY AD + R+LKL AGS TPT LPFT P GVAV++ VYV D Sbjct 21 PWGVAVDTAGNVYAADW-NNRVLKLAAGSTTPTELPFTGLHYPEGVAVDTAGAVYVADWR 79 Query 167 SHHVLKLAAGIEPPVELPF 185 + VLKLAAG P ELPF Sbjct 80 NLRVLKLAAGSSTPTELPF 98 Score = 51.6 bits (122), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 26/38 (69%), Positives = 30/38 (79%), Gaps = 0/38 (0%) Query 107 PDGVTVDLADAVYVADSGHKRLLKLPAGSNTPTTLPFT 144 P+GV VD A AVYVAD + R+LKL AGS+TPT LPFT Sbjct 62 PEGVAVDTAGAVYVADWRNLRVLKLAAGSSTPTELPFT 99 >gi|284039570|ref|YP_003389500.1| NHL repeat containing protein [Spirosoma linguale DSM 74] gi|283818863|gb|ADB40701.1| NHL repeat containing protein [Spirosoma linguale DSM 74] Length=1079 Score = 105 bits (262), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 75/231 (33%), Positives = 116/231 (51%), Gaps = 33/231 (14%) Query 103 DLWNPDGVTVDLADAVYVADSGHKRLLKLPAGSNTPTTLPFTDTIG--------PGGVAV 154 L +P GV VD A A+YV+D+ + R+ K +G+ + TT+ T T G P G+ V Sbjct 124 QLNHPLGVYVDGAGAIYVSDTDNNRVQKWASGATSGTTVAGTGTAGSAANQLNYPIGIYV 183 Query 155 NSNRDVYVIDEDSHHVLKLAAGIEPPVELPFGS--------LGDAHGLAVDRSDSVYVVD 206 + YV D + + K AAG + G+ L A G+ +D + ++YV D Sbjct 184 DGAGATYVADASNSRIQKWAAGATSGTTVAGGNGQGSAANQLWSAAGVYIDGAGAIYVAD 243 Query 207 YDNAKVLKLPPGADTPTELPFVG--------LDHPYDVAVDGAGTVYVTDSGHNRVVALT 258 N ++ K GA + T + G L +P+ V VDGAGT+YV+D +R+ T Sbjct 244 GGNNRIQKWASGATSGTTVAGTGVYGPASNQLSYPFAVYVDGAGTMYVSDQQSHRIQKWT 303 Query 259 AG--SATPVHLPFAD-------LSFPAGVTVDRDDSVYVADLNNNRVLKLA 300 AG S T V + + L++P G+ +DR ++YVAD NNR+ K + Sbjct 304 AGATSGTTVAGGYGNDALVPYQLNYPRGIYLDRAGAIYVADQRNNRIQKFS 354 Score = 97.4 bits (241), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 82/275 (30%), Positives = 132/275 (48%), Gaps = 43/275 (15%) Query 107 PDGVTVDLADAVYVADSGHKRLLKLPAGSNTPTTLPFTDTIG--------PGGVAVNSNR 158 P G+ VD A ++YVAD + R+ K +G+ + TT+ T T G P GV V+ Sbjct 78 PFGIYVDEAGSMYVADYNNHRVQKWASGATSGTTVAGTGTAGSAANQLNHPLGVYVDGAG 137 Query 159 DVYVIDEDSHHVLKLAAGIEPPVELP-FGSLGDAH-------GLAVDRSDSVYVVDYDNA 210 +YV D D++ V K A+G + G+ G A G+ VD + + YV D N+ Sbjct 138 AIYVSDTDNNRVQKWASGATSGTTVAGTGTAGSAANQLNYPIGIYVDGAGATYVADASNS 197 Query 211 KVLKLPPGADTPTELPFVG--------LDHPYDVAVDGAGTVYVTDSGHNRVVALTAG-- 260 ++ K GA + T + L V +DGAG +YV D G+NR+ +G Sbjct 198 RIQKWAAGATSGTTVAGGNGQGSAANQLWSAAGVYIDGAGAIYVADGGNNRIQKWASGAT 257 Query 261 -----SATPVHLPFAD-LSFPAGVTVDRDDSVYVADLNNNRVLKLAAGSNAQSQ------ 308 + T V+ P ++ LS+P V VD ++YV+D ++R+ K AG+ + + Sbjct 258 SGTTVAGTGVYGPASNQLSYPFAVYVDGAGTMYVSDQQSHRIQKWTAGATSGTTVAGGYG 317 Query 309 ----LPFTGLFSPTDVAVDNDGAVYVIDFYNRMLK 339 +P+ L P + +D GA+YV D N ++ Sbjct 318 NDALVPYQ-LNYPRGIYLDRAGAIYVADQRNNRIQ 351 Score = 90.5 bits (223), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 68/227 (30%), Positives = 109/227 (49%), Gaps = 32/227 (14%) Query 149 PGGVAVNSNRDVYVIDEDSHHVLKLAAGIEPPVELP-FGSLGDAH-------GLAVDRSD 200 P G+ V+ +YV D ++H V K A+G + G+ G A G+ VD + Sbjct 78 PFGIYVDEAGSMYVADYNNHRVQKWASGATSGTTVAGTGTAGSAANQLNHPLGVYVDGAG 137 Query 201 SVYVVDYDNAKVLKLPPGADTPTELPFVG--------LDHPYDVAVDGAGTVYVTDSGHN 252 ++YV D DN +V K GA + T + G L++P + VDGAG YV D+ ++ Sbjct 138 AIYVSDTDNNRVQKWASGATSGTTVAGTGTAGSAANQLNYPIGIYVDGAGATYVADASNS 197 Query 253 RVVALTAGSATPVHLPFAD--------LSFPAGVTVDRDDSVYVADLNNNRVLKLAAGSN 304 R+ AG+ + + + L AGV +D ++YVAD NNR+ K A+G+ Sbjct 198 RIQKWAAGATSGTTVAGGNGQGSAANQLWSAAGVYIDGAGAIYVADGGNNRIQKWASGAT 257 Query 305 AQSQLPFTGLFSPTD--------VAVDNDGAVYVIDFYNRMLKLPTA 343 + + + TG++ P V VD G +YV D + ++ TA Sbjct 258 SGTTVAGTGVYGPASNQLSYPFAVYVDGAGTMYVSDQQSHRIQKWTA 304 Score = 47.4 bits (111), Expect = 0.003, Method: Compositional matrix adjust. Identities = 35/90 (39%), Positives = 46/90 (52%), Gaps = 14/90 (15%) Query 258 TAGSATPVHLPFADLSFPAGVTVDRDDSVYVADLNNNRVLKLAAGSNAQSQLPFTG---- 313 TAGSA L P G+ VD S+YVAD NN+RV K A+G+ + + + TG Sbjct 67 TAGSAAN------QLDSPFGIYVDEAGSMYVADYNNHRVQKWASGATSGTTVAGTGTAGS 120 Query 314 ----LFSPTDVAVDNDGAVYVIDFYNRMLK 339 L P V VD GA+YV D N ++ Sbjct 121 AANQLNHPLGVYVDGAGAIYVSDTDNNRVQ 150 >gi|73667964|ref|YP_303979.1| hypothetical protein Mbar_A0416 [Methanosarcina barkeri str. Fusaro] gi|72395126|gb|AAZ69399.1| conserved hypothetical protein [Methanosarcina barkeri str. Fusaro] Length=346 Score = 103 bits (257), Expect = 4e-20, Method: Compositional matrix adjust. Identities = 88/271 (33%), Positives = 123/271 (46%), Gaps = 42/271 (15%) Query 107 PDGVTVDLADAVYVADSGHKRLLKLPA--------GSNTPTTLPFTDTIGPGGVAVNSNR 158 P GV VD + VYV D+G+ R+ K + GSN F P GVAV+S+ Sbjct 53 PTGVAVDSSGNVYVTDTGNHRIQKFNSTGGYLTQWGSNGTDNRQF---FLPYGVAVDSSG 109 Query 159 DVYVIDEDSHHVLKLAAGIEPPVELPFGSLGDAHG-------LAVDRSDSVYVVDYDNAK 211 +VYV D+ + + K + + +GS G+ +G +AVD S +VYV D N + Sbjct 110 NVYVADKGNKCIQKFNSNGGHLTQ--WGSSGNGNGQFYFLNGVAVDSSGNVYVADSGNNR 167 Query 212 VLKLPPGADTPTELPFVG-----LDHPYDVAVDGAGTVYVTDSGHNRVVAL--TAGSATP 264 + K T+ G + P VAVD +G VYV DSG+NR+ T G T Sbjct 168 IQKFNSNGGYLTQWGSYGSGNGQFNDPEGVAVDSSGNVYVADSGNNRIQKFNSTGGYLTQ 227 Query 265 ---VHLPFADLSFPAGVTVDRDDSVYVADLNNNRVLKLAA--------GSNAQSQLPF-- 311 FP + VD +VYVAD N R+ K + GSN Sbjct 228 WGSYGSGNGQFEFPLSIAVDSSGNVYVADKYNQRIQKFNSIGRYLTQWGSNGTDNRQIYD 287 Query 312 -TGLFSPTDVAVDNDGAVYVIDF-YNRMLKL 340 G++ P VAVD+ G VYV + Y+R+ K Sbjct 288 PNGIYDPNGVAVDSSGNVYVAETGYSRIQKF 318 Score = 76.6 bits (187), Expect = 5e-12, Method: Compositional matrix adjust. Identities = 68/223 (31%), Positives = 98/223 (44%), Gaps = 32/223 (14%) Query 107 PDGVTVDLADAVYVADSGHKRLLKLPAGSNTPTTLPFTDTIGPG------GVAVNSNRDV 160 P GV VD + VYVAD G+K + K + T + G G GVAV+S+ +V Sbjct 100 PYGVAVDSSGNVYVADKGNKCIQKFNSNGGHLTQWGSSGN-GNGQFYFLNGVAVDSSGNV 158 Query 161 YVIDEDSHHVLKLAAGIEPPVELPFGSLG-------DAHGLAVDRSDSVYVVDYDNAKVL 213 YV D ++ + K + +GS G D G+AVD S +VYV D N ++ Sbjct 159 YVADSGNNRIQKFNS--NGGYLTQWGSYGSGNGQFNDPEGVAVDSSGNVYVADSGNNRIQ 216 Query 214 KLPPGADTPTELPFVG-----LDHPYDVAVDGAGTVYVTDSGHNRVVALTA--------G 260 K T+ G + P +AVD +G VYV D + R+ + G Sbjct 217 KFNSTGGYLTQWGSYGSGNGQFEFPLSIAVDSSGNVYVADKYNQRIQKFNSIGRYLTQWG 276 Query 261 SATPVHLPFAD---LSFPAGVTVDRDDSVYVADLNNNRVLKLA 300 S + D + P GV VD +VYVA+ +R+ K A Sbjct 277 SNGTDNRQIYDPNGIYDPNGVAVDSSGNVYVAETGYSRIQKFA 319 Score = 49.3 bits (116), Expect = 0.001, Method: Compositional matrix adjust. Identities = 40/132 (31%), Positives = 62/132 (47%), Gaps = 26/132 (19%) Query 107 PDGVTVDLADAVYVADSGHKRLLKLPAGSNTPTTLPFTDTIGPGG--------VAVNSNR 158 P+GV VD + VYVADSG+ R+ K + T L + G G +AV+S+ Sbjct 194 PEGVAVDSSGNVYVADSGNNRIQKFNS---TGGYLTQWGSYGSGNGQFEFPLSIAVDSSG 250 Query 159 DVYVIDEDSHHVLKLAAGIEPPVELPFGSLG-------------DAHGLAVDRSDSVYVV 205 +VYV D+ + + K + +GS G D +G+AVD S +VYV Sbjct 251 NVYVADKYNQRIQKFNS--IGRYLTQWGSNGTDNRQIYDPNGIYDPNGVAVDSSGNVYVA 308 Query 206 DYDNAKVLKLPP 217 + +++ K P Sbjct 309 ETGYSRIQKFAP 320 >gi|299137977|ref|ZP_07031157.1| NHL repeat containing protein [Acidobacterium sp. MP5ACTX8] gi|298599907|gb|EFI56065.1| NHL repeat containing protein [Acidobacterium sp. MP5ACTX8] Length=334 Score = 102 bits (255), Expect = 7e-20, Method: Compositional matrix adjust. Identities = 85/243 (35%), Positives = 121/243 (50%), Gaps = 24/243 (9%) Query 96 SQVVVPIDLWNPDGVTVDLADAVYVADSGHKRLLKLPAGSNTPTTLPFTDTIGPGGVAVN 155 +VVV L+ P V VD VYVADS H R+LK TP+ + + G+A++ Sbjct 47 QRVVVDKGLYYPYSVAVDGHGNVYVADSRHNRVLK-----ETPSGEGYIQSNVVVGLALS 101 Query 156 SNRDVYVIDEDSHHVLKLAAGIE-PPVELPFGSLGDAHGLAVDRSDSVYVVDYDNAKVLK 214 +D D H L G + V+ P+G LAVD VY+ DY N +VLK Sbjct 102 FGT---ALDNDGH----LTEGAKRGEVDRPYG-------LAVDGDGDVYISDYGNDRVLK 147 Query 215 LPPGADTPTE-LPFVGLDHPYDVAVDGAGTVYVTDSGHNRVVALT--AGSATPVHLPFAD 271 P T T+ + + PY +AVD G+VY+ D G NRV + G+ + + Sbjct 148 ETPSGHTYTQTVVTTDVQSPYGLAVDNHGSVYIADYGRNRVTKESPSGGNYVESVVAGSG 207 Query 272 LSFPAGVTVDRDDSVYVADLNNNRVLKLAA-GSNAQSQLPFTGLFSPTDVAVDNDGAVYV 330 L P GV VDR+ +VY+AD +N+RVLK + G+ + SP VAVD G VY+ Sbjct 208 LRGPEGVAVDREGNVYIADSDNDRVLKESVLGTGYVESTLVDDMASPRGVAVDGSGNVYI 267 Query 331 IDF 333 + + Sbjct 268 VSY 270 Lambda K H 0.316 0.134 0.398 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 626808148204 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40