BLASTP 2.2.25+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.



Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
           15,229,318 sequences; 5,219,829,388 total letters



Query= Rv3532

Length=406
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

gi|31794708|ref|NP_857201.1|  PPE family protein [Mycobacterium b...   795    0.0   
gi|339633530|ref|YP_004725172.1|  PPE family protein [Mycobacteri...   795    0.0   
gi|289572184|ref|ZP_06452411.1|  PPE family protein [Mycobacteriu...   794    0.0   
gi|289440961|ref|ZP_06430705.1|  PPE family protein [Mycobacteriu...   793    0.0   
gi|308232493|ref|ZP_07416221.2|  PPE family protein [Mycobacteriu...   791    0.0   
gi|298527010|ref|ZP_07014419.1|  ppe family protein [Mycobacteriu...   714    0.0   
gi|289755661|ref|ZP_06515039.1|  PPE family protein [Mycobacteriu...   712    0.0   
gi|289445124|ref|ZP_06434868.1|  PPE family protein [Mycobacteriu...   529    4e-148
gi|323717805|gb|EGB27002.1|  hypothetical protein TMMG_00021 [Myc...   514    1e-143
gi|240173322|ref|ZP_04751980.1|  PPE family protein [Mycobacteriu...   452    5e-125
gi|183983433|ref|YP_001851724.1|  PPE family protein, PPE61 [Myco...   429    3e-118
gi|183983432|ref|YP_001851723.1|  PPE family protein, PPE61_1 [My...   426    3e-117
gi|240169296|ref|ZP_04747955.1|  PPE family protein [Mycobacteriu...   412    4e-113
gi|118618170|ref|YP_906502.1|  PPE family protein [Mycobacterium ...   399    6e-109
gi|183980225|ref|YP_001848516.1|  PPE family protein, PPE51_2 [My...   366    3e-99 
gi|240168615|ref|ZP_04747274.1|  PPE family protein [Mycobacteriu...   316    5e-84 
gi|31794311|ref|NP_856804.1|  PPE family protein [Mycobacterium b...   309    6e-82 
gi|121639018|ref|YP_979242.1|  PPE family protein [Mycobacterium ...   308    1e-81 
gi|340628111|ref|YP_004746563.1|  ppe family protein [Mycobacteri...   307    2e-81 
gi|183981528|ref|YP_001849819.1|  PPE family protein, PPE51 [Myco...   306    5e-81 
gi|224991510|ref|YP_002646199.1|  PPE family protein [Mycobacteri...   306    6e-81 
gi|118617919|ref|YP_906251.1|  PPE family protein [Mycobacterium ...   303    5e-80 
gi|340628112|ref|YP_004746564.1|  PPE family protein [Mycobacteri...   298    8e-79 
gi|15842710|ref|NP_337747.1|  PPE family protein [Mycobacterium t...   298    9e-79 
gi|306782177|ref|ZP_07420514.1|  PPE family protein [Mycobacteriu...   298    1e-78 
gi|183981529|ref|YP_001849820.1|  PPE family protein, PPE51_1 [My...   292    6e-77 
gi|240168614|ref|ZP_04747273.1|  PPE family protein, PPE51_2 [Myc...   285    1e-74 
gi|118618187|ref|YP_906519.1|  PPE family protein [Mycobacterium ...   282    8e-74 
gi|167970194|ref|ZP_02552471.1|  PPE family protein [Mycobacteriu...   281    1e-73 
gi|118617918|ref|YP_906250.1|  PPE family protein [Mycobacterium ...   279    6e-73 
gi|323717804|gb|EGB27001.1|  hypothetical protein TMMG_00020 [Myc...   276    4e-72 
gi|183983449|ref|YP_001851740.1|  PPE family protein, PPE51_3 [My...   268    1e-69 
gi|289448814|ref|ZP_06438558.1|  PPE family protein [Mycobacteriu...   260    3e-67 
gi|289575846|ref|ZP_06456073.1|  PPE family protein [Mycobacteriu...   250    3e-64 
gi|240172861|ref|ZP_04751520.1|  PPE family protein, PPE31 [Mycob...   227    2e-57 
gi|41409283|ref|NP_962119.1|  hypothetical protein MAP3185 [Mycob...   224    2e-56 
gi|118466535|ref|YP_883168.1|  PPE family protein [Mycobacterium ...   224    3e-56 
gi|212596159|gb|ACJ35556.1|  PPE33 [Mycobacterium avium subsp. av...   220    4e-55 
gi|183982688|ref|YP_001850979.1|  PPE family protein, PPE31_1 [My...   214    2e-53 
gi|183982689|ref|YP_001850980.1|  PPE family protein [Mycobacteri...   205    1e-50 
gi|183981114|ref|YP_001849405.1|  PPE family protein [Mycobacteri...   199    8e-49 
gi|296167733|ref|ZP_06849950.1|  PPE family protein [Mycobacteriu...   198    1e-48 
gi|342861033|ref|ZP_08717682.1|  PPE family protein [Mycobacteriu...   196    5e-48 
gi|240169314|ref|ZP_04747973.1|  PPE family protein [Mycobacteriu...   192    7e-47 
gi|212596661|gb|ACJ35596.1|  PPE32 [Mycobacterium intracellulare ...   192    1e-46 
gi|118618459|ref|YP_906791.1|  PPE family protein [Mycobacterium ...   192    1e-46 
gi|57116920|ref|YP_177653.1|  PPE family protein [Mycobacterium t...   192    1e-46 
gi|148661613|ref|YP_001283136.1|  PPE family protein [Mycobacteri...   191    1e-46 
gi|289574372|ref|ZP_06454599.1|  PPE family protein [Mycobacteriu...   191    3e-46 
gi|289759264|ref|ZP_06518642.1|  PPE family protein [Mycobacteriu...   190    3e-46 


>gi|31794708|ref|NP_857201.1| PPE family protein [Mycobacterium bovis AF2122/97]
 gi|57117120|ref|YP_177984.1| PPE family protein [Mycobacterium tuberculosis H37Rv]
 gi|121639451|ref|YP_979675.1| PPE family protein [Mycobacterium bovis BCG str. Pasteur 1173P2]
 50 more sequence titles
 Length=406

 Score =  795 bits (2054),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 406/406 (100%), Positives = 406/406 (100%), Gaps = 0/406 (0%)

Query  1    MFMDFAMLPPEVNSTRMYSGPGAGSLWAAAAAWDQVSAELQSAAETYRSVIASLTGWQWL  60
            MFMDFAMLPPEVNSTRMYSGPGAGSLWAAAAAWDQVSAELQSAAETYRSVIASLTGWQWL
Sbjct  1    MFMDFAMLPPEVNSTRMYSGPGAGSLWAAAAAWDQVSAELQSAAETYRSVIASLTGWQWL  60

Query  61   GPSSVRMGAAVTPYVEWLTTTAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVL  120
            GPSSVRMGAAVTPYVEWLTTTAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVL
Sbjct  61   GPSSVRMGAAVTPYVEWLTTTAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVL  120

Query  121  SLIATNFFGQNTAAIAALETQYAEMWEQDATAMYDYAATSAAARTLTPFTSPQQDTNSAG  180
            SLIATNFFGQNTAAIAALETQYAEMWEQDATAMYDYAATSAAARTLTPFTSPQQDTNSAG
Sbjct  121  SLIATNFFGQNTAAIAALETQYAEMWEQDATAMYDYAATSAAARTLTPFTSPQQDTNSAG  180

Query  181  LPAQSAEVSRATANAGAADGNWLGNLLEEIGILLLPIAPELTPFFLEAGEIVNAIPFPSI  240
            LPAQSAEVSRATANAGAADGNWLGNLLEEIGILLLPIAPELTPFFLEAGEIVNAIPFPSI
Sbjct  181  LPAQSAEVSRATANAGAADGNWLGNLLEEIGILLLPIAPELTPFFLEAGEIVNAIPFPSI  240

Query  241  VGDEFCLLDGLLAWYATIGSINNINSMGTGIIGAEKNLGILPELGSAAAAAAPPPADIAP  300
            VGDEFCLLDGLLAWYATIGSINNINSMGTGIIGAEKNLGILPELGSAAAAAAPPPADIAP
Sbjct  241  VGDEFCLLDGLLAWYATIGSINNINSMGTGIIGAEKNLGILPELGSAAAAAAPPPADIAP  300

Query  301  AFLAPLTSMAKSLSDGALRGPGEVSAAMRGAGTIGQMSVPPAWKAPAVTTVRAFDATPMT  360
            AFLAPLTSMAKSLSDGALRGPGEVSAAMRGAGTIGQMSVPPAWKAPAVTTVRAFDATPMT
Sbjct  301  AFLAPLTSMAKSLSDGALRGPGEVSAAMRGAGTIGQMSVPPAWKAPAVTTVRAFDATPMT  360

Query  361  TLPGGDAPAAGVPGLPGMPASGAGRAGVVPRYGVRLTVMTRPLSGG  406
            TLPGGDAPAAGVPGLPGMPASGAGRAGVVPRYGVRLTVMTRPLSGG
Sbjct  361  TLPGGDAPAAGVPGLPGMPASGAGRAGVVPRYGVRLTVMTRPLSGG  406


>gi|339633530|ref|YP_004725172.1| PPE family protein [Mycobacterium africanum GM041182]
 gi|339332886|emb|CCC28613.1| PPE family protein [Mycobacterium africanum GM041182]
Length=406

 Score =  795 bits (2052),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 405/406 (99%), Positives = 406/406 (100%), Gaps = 0/406 (0%)

Query  1    MFMDFAMLPPEVNSTRMYSGPGAGSLWAAAAAWDQVSAELQSAAETYRSVIASLTGWQWL  60
            MFMDFAMLPPEVNSTRMYSGPGAGSLWAAAAAWDQVSAELQSAAETYRS+IASLTGWQWL
Sbjct  1    MFMDFAMLPPEVNSTRMYSGPGAGSLWAAAAAWDQVSAELQSAAETYRSMIASLTGWQWL  60

Query  61   GPSSVRMGAAVTPYVEWLTTTAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVL  120
            GPSSVRMGAAVTPYVEWLTTTAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVL
Sbjct  61   GPSSVRMGAAVTPYVEWLTTTAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVL  120

Query  121  SLIATNFFGQNTAAIAALETQYAEMWEQDATAMYDYAATSAAARTLTPFTSPQQDTNSAG  180
            SLIATNFFGQNTAAIAALETQYAEMWEQDATAMYDYAATSAAARTLTPFTSPQQDTNSAG
Sbjct  121  SLIATNFFGQNTAAIAALETQYAEMWEQDATAMYDYAATSAAARTLTPFTSPQQDTNSAG  180

Query  181  LPAQSAEVSRATANAGAADGNWLGNLLEEIGILLLPIAPELTPFFLEAGEIVNAIPFPSI  240
            LPAQSAEVSRATANAGAADGNWLGNLLEEIGILLLPIAPELTPFFLEAGEIVNAIPFPSI
Sbjct  181  LPAQSAEVSRATANAGAADGNWLGNLLEEIGILLLPIAPELTPFFLEAGEIVNAIPFPSI  240

Query  241  VGDEFCLLDGLLAWYATIGSINNINSMGTGIIGAEKNLGILPELGSAAAAAAPPPADIAP  300
            VGDEFCLLDGLLAWYATIGSINNINSMGTGIIGAEKNLGILPELGSAAAAAAPPPADIAP
Sbjct  241  VGDEFCLLDGLLAWYATIGSINNINSMGTGIIGAEKNLGILPELGSAAAAAAPPPADIAP  300

Query  301  AFLAPLTSMAKSLSDGALRGPGEVSAAMRGAGTIGQMSVPPAWKAPAVTTVRAFDATPMT  360
            AFLAPLTSMAKSLSDGALRGPGEVSAAMRGAGTIGQMSVPPAWKAPAVTTVRAFDATPMT
Sbjct  301  AFLAPLTSMAKSLSDGALRGPGEVSAAMRGAGTIGQMSVPPAWKAPAVTTVRAFDATPMT  360

Query  361  TLPGGDAPAAGVPGLPGMPASGAGRAGVVPRYGVRLTVMTRPLSGG  406
            TLPGGDAPAAGVPGLPGMPASGAGRAGVVPRYGVRLTVMTRPLSGG
Sbjct  361  TLPGGDAPAAGVPGLPGMPASGAGRAGVVPRYGVRLTVMTRPLSGG  406


>gi|289572184|ref|ZP_06452411.1| PPE family protein [Mycobacterium tuberculosis K85]
 gi|289536615|gb|EFD41193.1| PPE family protein [Mycobacterium tuberculosis K85]
Length=406

 Score =  794 bits (2050),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 405/406 (99%), Positives = 405/406 (99%), Gaps = 0/406 (0%)

Query  1    MFMDFAMLPPEVNSTRMYSGPGAGSLWAAAAAWDQVSAELQSAAETYRSVIASLTGWQWL  60
            MFMDFAMLPPEVNSTRMYSGPGAGSLWAAAAAWDQVSAELQSAAETYRSVIASLTGWQWL
Sbjct  1    MFMDFAMLPPEVNSTRMYSGPGAGSLWAAAAAWDQVSAELQSAAETYRSVIASLTGWQWL  60

Query  61   GPSSVRMGAAVTPYVEWLTTTAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVL  120
            GPSSVRMGAAVTPYVEWLTTTAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVL
Sbjct  61   GPSSVRMGAAVTPYVEWLTTTAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVL  120

Query  121  SLIATNFFGQNTAAIAALETQYAEMWEQDATAMYDYAATSAAARTLTPFTSPQQDTNSAG  180
            SLIATNFFGQNTAAIAALETQYAEMWEQDATAMYDYAATSAAARTLTPFTSPQQDTNSAG
Sbjct  121  SLIATNFFGQNTAAIAALETQYAEMWEQDATAMYDYAATSAAARTLTPFTSPQQDTNSAG  180

Query  181  LPAQSAEVSRATANAGAADGNWLGNLLEEIGILLLPIAPELTPFFLEAGEIVNAIPFPSI  240
            LPAQSAEVSRATANAGAADGNWLGNLLEEIGILLLPIAPELTPFFLEAGEIVNAIPFPSI
Sbjct  181  LPAQSAEVSRATANAGAADGNWLGNLLEEIGILLLPIAPELTPFFLEAGEIVNAIPFPSI  240

Query  241  VGDEFCLLDGLLAWYATIGSINNINSMGTGIIGAEKNLGILPELGSAAAAAAPPPADIAP  300
            VGDEFCLLDGLLAWYATIGSINNINSMGTGIIGAEKNLGILPELGSAAAAAAPPPADIAP
Sbjct  241  VGDEFCLLDGLLAWYATIGSINNINSMGTGIIGAEKNLGILPELGSAAAAAAPPPADIAP  300

Query  301  AFLAPLTSMAKSLSDGALRGPGEVSAAMRGAGTIGQMSVPPAWKAPAVTTVRAFDATPMT  360
            AFLAPLTSMAKSLSDGALRGPGEVSAAMRGAGTIGQMSVPPAWKAPAVTTVRAFDATPMT
Sbjct  301  AFLAPLTSMAKSLSDGALRGPGEVSAAMRGAGTIGQMSVPPAWKAPAVTTVRAFDATPMT  360

Query  361  TLPGGDAPAAGVPGLPGMPASGAGRAGVVPRYGVRLTVMTRPLSGG  406
            TLPGGD PAAGVPGLPGMPASGAGRAGVVPRYGVRLTVMTRPLSGG
Sbjct  361  TLPGGDVPAAGVPGLPGMPASGAGRAGVVPRYGVRLTVMTRPLSGG  406


>gi|289440961|ref|ZP_06430705.1| PPE family protein [Mycobacterium tuberculosis T46]
 gi|289571773|ref|ZP_06452000.1| PPE family protein [Mycobacterium tuberculosis T17]
 gi|289752245|ref|ZP_06511623.1| PPE family protein [Mycobacterium tuberculosis T92]
 gi|289413880|gb|EFD11120.1| PPE family protein [Mycobacterium tuberculosis T46]
 gi|289545527|gb|EFD49175.1| PPE family protein [Mycobacterium tuberculosis T17]
 gi|289692832|gb|EFD60261.1| PPE family protein [Mycobacterium tuberculosis T92]
Length=406

 Score =  793 bits (2049),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 405/406 (99%), Positives = 405/406 (99%), Gaps = 0/406 (0%)

Query  1    MFMDFAMLPPEVNSTRMYSGPGAGSLWAAAAAWDQVSAELQSAAETYRSVIASLTGWQWL  60
            MFMDFAMLPPEVNSTRMYSGPGAGSLWAAAAAWDQVSAELQSAAETYRSVIASLTGWQWL
Sbjct  1    MFMDFAMLPPEVNSTRMYSGPGAGSLWAAAAAWDQVSAELQSAAETYRSVIASLTGWQWL  60

Query  61   GPSSVRMGAAVTPYVEWLTTTAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVL  120
            GPSSVRMGAAVTPYVEWLTTTAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVL
Sbjct  61   GPSSVRMGAAVTPYVEWLTTTAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVL  120

Query  121  SLIATNFFGQNTAAIAALETQYAEMWEQDATAMYDYAATSAAARTLTPFTSPQQDTNSAG  180
            SLIATNFFGQNTAAIAALETQYAEMWEQDATAMYDYAATSAAARTLTPFTSPQQDTNSAG
Sbjct  121  SLIATNFFGQNTAAIAALETQYAEMWEQDATAMYDYAATSAAARTLTPFTSPQQDTNSAG  180

Query  181  LPAQSAEVSRATANAGAADGNWLGNLLEEIGILLLPIAPELTPFFLEAGEIVNAIPFPSI  240
            LPAQSAEVSRATANAGAADGNWLGNLLEEIGILLLPIAPELTPFFLEAGEIVNAIPFPSI
Sbjct  181  LPAQSAEVSRATANAGAADGNWLGNLLEEIGILLLPIAPELTPFFLEAGEIVNAIPFPSI  240

Query  241  VGDEFCLLDGLLAWYATIGSINNINSMGTGIIGAEKNLGILPELGSAAAAAAPPPADIAP  300
            VGDEFCLLDGLLAWYA IGSINNINSMGTGIIGAEKNLGILPELGSAAAAAAPPPADIAP
Sbjct  241  VGDEFCLLDGLLAWYAMIGSINNINSMGTGIIGAEKNLGILPELGSAAAAAAPPPADIAP  300

Query  301  AFLAPLTSMAKSLSDGALRGPGEVSAAMRGAGTIGQMSVPPAWKAPAVTTVRAFDATPMT  360
            AFLAPLTSMAKSLSDGALRGPGEVSAAMRGAGTIGQMSVPPAWKAPAVTTVRAFDATPMT
Sbjct  301  AFLAPLTSMAKSLSDGALRGPGEVSAAMRGAGTIGQMSVPPAWKAPAVTTVRAFDATPMT  360

Query  361  TLPGGDAPAAGVPGLPGMPASGAGRAGVVPRYGVRLTVMTRPLSGG  406
            TLPGGDAPAAGVPGLPGMPASGAGRAGVVPRYGVRLTVMTRPLSGG
Sbjct  361  TLPGGDAPAAGVPGLPGMPASGAGRAGVVPRYGVRLTVMTRPLSGG  406


>gi|308232493|ref|ZP_07416221.2| PPE family protein [Mycobacterium tuberculosis SUMu001]
 gi|308369156|ref|ZP_07416751.2| PPE family protein [Mycobacterium tuberculosis SUMu002]
 gi|308371381|ref|ZP_07424759.2| PPE family protein [Mycobacterium tuberculosis SUMu003]
 9 more sequence titles
 Length=404

 Score =  791 bits (2042),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 404/404 (100%), Positives = 404/404 (100%), Gaps = 0/404 (0%)

Query  3    MDFAMLPPEVNSTRMYSGPGAGSLWAAAAAWDQVSAELQSAAETYRSVIASLTGWQWLGP  62
            MDFAMLPPEVNSTRMYSGPGAGSLWAAAAAWDQVSAELQSAAETYRSVIASLTGWQWLGP
Sbjct  1    MDFAMLPPEVNSTRMYSGPGAGSLWAAAAAWDQVSAELQSAAETYRSVIASLTGWQWLGP  60

Query  63   SSVRMGAAVTPYVEWLTTTAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVLSL  122
            SSVRMGAAVTPYVEWLTTTAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVLSL
Sbjct  61   SSVRMGAAVTPYVEWLTTTAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVLSL  120

Query  123  IATNFFGQNTAAIAALETQYAEMWEQDATAMYDYAATSAAARTLTPFTSPQQDTNSAGLP  182
            IATNFFGQNTAAIAALETQYAEMWEQDATAMYDYAATSAAARTLTPFTSPQQDTNSAGLP
Sbjct  121  IATNFFGQNTAAIAALETQYAEMWEQDATAMYDYAATSAAARTLTPFTSPQQDTNSAGLP  180

Query  183  AQSAEVSRATANAGAADGNWLGNLLEEIGILLLPIAPELTPFFLEAGEIVNAIPFPSIVG  242
            AQSAEVSRATANAGAADGNWLGNLLEEIGILLLPIAPELTPFFLEAGEIVNAIPFPSIVG
Sbjct  181  AQSAEVSRATANAGAADGNWLGNLLEEIGILLLPIAPELTPFFLEAGEIVNAIPFPSIVG  240

Query  243  DEFCLLDGLLAWYATIGSINNINSMGTGIIGAEKNLGILPELGSAAAAAAPPPADIAPAF  302
            DEFCLLDGLLAWYATIGSINNINSMGTGIIGAEKNLGILPELGSAAAAAAPPPADIAPAF
Sbjct  241  DEFCLLDGLLAWYATIGSINNINSMGTGIIGAEKNLGILPELGSAAAAAAPPPADIAPAF  300

Query  303  LAPLTSMAKSLSDGALRGPGEVSAAMRGAGTIGQMSVPPAWKAPAVTTVRAFDATPMTTL  362
            LAPLTSMAKSLSDGALRGPGEVSAAMRGAGTIGQMSVPPAWKAPAVTTVRAFDATPMTTL
Sbjct  301  LAPLTSMAKSLSDGALRGPGEVSAAMRGAGTIGQMSVPPAWKAPAVTTVRAFDATPMTTL  360

Query  363  PGGDAPAAGVPGLPGMPASGAGRAGVVPRYGVRLTVMTRPLSGG  406
            PGGDAPAAGVPGLPGMPASGAGRAGVVPRYGVRLTVMTRPLSGG
Sbjct  361  PGGDAPAAGVPGLPGMPASGAGRAGVVPRYGVRLTVMTRPLSGG  404


>gi|298527010|ref|ZP_07014419.1| ppe family protein [Mycobacterium tuberculosis 94_M4241A]
 gi|298496804|gb|EFI32098.1| ppe family protein [Mycobacterium tuberculosis 94_M4241A]
Length=405

 Score =  714 bits (1843),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 405/406 (99%), Positives = 405/406 (99%), Gaps = 1/406 (0%)

Query  1    MFMDFAMLPPEVNSTRMYSGPGAGSLWAAAAAWDQVSAELQSAAETYRSVIASLTGWQWL  60
            MFMDFAMLPPEVNSTRMYSGPGAGSLWAAAA WDQVSAELQSAAETYRSVIASLTGWQWL
Sbjct  1    MFMDFAMLPPEVNSTRMYSGPGAGSLWAAAA-WDQVSAELQSAAETYRSVIASLTGWQWL  59

Query  61   GPSSVRMGAAVTPYVEWLTTTAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVL  120
            GPSSVRMGAAVTPYVEWLTTTAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVL
Sbjct  60   GPSSVRMGAAVTPYVEWLTTTAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVL  119

Query  121  SLIATNFFGQNTAAIAALETQYAEMWEQDATAMYDYAATSAAARTLTPFTSPQQDTNSAG  180
            SLIATNFFGQNTAAIAALETQYAEMWEQDATAMYDYAATSAAARTLTPFTSPQQDTNSAG
Sbjct  120  SLIATNFFGQNTAAIAALETQYAEMWEQDATAMYDYAATSAAARTLTPFTSPQQDTNSAG  179

Query  181  LPAQSAEVSRATANAGAADGNWLGNLLEEIGILLLPIAPELTPFFLEAGEIVNAIPFPSI  240
            LPAQSAEVSRATANAGAADGNWLGNLLEEIGILLLPIAPELTPFFLEAGEIVNAIPFPSI
Sbjct  180  LPAQSAEVSRATANAGAADGNWLGNLLEEIGILLLPIAPELTPFFLEAGEIVNAIPFPSI  239

Query  241  VGDEFCLLDGLLAWYATIGSINNINSMGTGIIGAEKNLGILPELGSAAAAAAPPPADIAP  300
            VGDEFCLLDGLLAWYATIGSINNINSMGTGIIGAEKNLGILPELGSAAAAAAPPPADIAP
Sbjct  240  VGDEFCLLDGLLAWYATIGSINNINSMGTGIIGAEKNLGILPELGSAAAAAAPPPADIAP  299

Query  301  AFLAPLTSMAKSLSDGALRGPGEVSAAMRGAGTIGQMSVPPAWKAPAVTTVRAFDATPMT  360
            AFLAPLTSMAKSLSDGALRGPGEVSAAMRGAGTIGQMSVPPAWKAPAVTTVRAFDATPMT
Sbjct  300  AFLAPLTSMAKSLSDGALRGPGEVSAAMRGAGTIGQMSVPPAWKAPAVTTVRAFDATPMT  359

Query  361  TLPGGDAPAAGVPGLPGMPASGAGRAGVVPRYGVRLTVMTRPLSGG  406
            TLPGGDAPAAGVPGLPGMPASGAGRAGVVPRYGVRLTVMTRPLSGG
Sbjct  360  TLPGGDAPAAGVPGLPGMPASGAGRAGVVPRYGVRLTVMTRPLSGG  405


>gi|289755661|ref|ZP_06515039.1| PPE family protein [Mycobacterium tuberculosis EAS054]
 gi|289696248|gb|EFD63677.1| PPE family protein [Mycobacterium tuberculosis EAS054]
Length=405

 Score =  712 bits (1838),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 404/406 (99%), Positives = 404/406 (99%), Gaps = 1/406 (0%)

Query  1    MFMDFAMLPPEVNSTRMYSGPGAGSLWAAAAAWDQVSAELQSAAETYRSVIASLTGWQWL  60
            MFMDFAMLPPEVNSTRMYSGPGAGSLWAAAA WDQVSAELQSAAETYRSVIASLTGWQWL
Sbjct  1    MFMDFAMLPPEVNSTRMYSGPGAGSLWAAAA-WDQVSAELQSAAETYRSVIASLTGWQWL  59

Query  61   GPSSVRMGAAVTPYVEWLTTTAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVL  120
            GPSSVRMGAAVTPYVEWLTTTAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVL
Sbjct  60   GPSSVRMGAAVTPYVEWLTTTAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVL  119

Query  121  SLIATNFFGQNTAAIAALETQYAEMWEQDATAMYDYAATSAAARTLTPFTSPQQDTNSAG  180
            SLIATNFFGQNTAAIAALETQYAEMWEQDATAMYDYAATSAAARTLTPFTSPQQDTNSAG
Sbjct  120  SLIATNFFGQNTAAIAALETQYAEMWEQDATAMYDYAATSAAARTLTPFTSPQQDTNSAG  179

Query  181  LPAQSAEVSRATANAGAADGNWLGNLLEEIGILLLPIAPELTPFFLEAGEIVNAIPFPSI  240
            LPAQSAEVSRATANAGAADGNWLGNLLEEIGILLLPIAPELTPFFLEAGEIVNAIPFPSI
Sbjct  180  LPAQSAEVSRATANAGAADGNWLGNLLEEIGILLLPIAPELTPFFLEAGEIVNAIPFPSI  239

Query  241  VGDEFCLLDGLLAWYATIGSINNINSMGTGIIGAEKNLGILPELGSAAAAAAPPPADIAP  300
            VGDEFCLLDGLLAWYA IGSINNINSMGTGIIGAEKNLGILPELGSAAAAAAPPPADIAP
Sbjct  240  VGDEFCLLDGLLAWYAMIGSINNINSMGTGIIGAEKNLGILPELGSAAAAAAPPPADIAP  299

Query  301  AFLAPLTSMAKSLSDGALRGPGEVSAAMRGAGTIGQMSVPPAWKAPAVTTVRAFDATPMT  360
            AFLAPLTSMAKSLSDGALRGPGEVSAAMRGAGTIGQMSVPPAWKAPAVTTVRAFDATPMT
Sbjct  300  AFLAPLTSMAKSLSDGALRGPGEVSAAMRGAGTIGQMSVPPAWKAPAVTTVRAFDATPMT  359

Query  361  TLPGGDAPAAGVPGLPGMPASGAGRAGVVPRYGVRLTVMTRPLSGG  406
            TLPGGDAPAAGVPGLPGMPASGAGRAGVVPRYGVRLTVMTRPLSGG
Sbjct  360  TLPGGDAPAAGVPGLPGMPASGAGRAGVVPRYGVRLTVMTRPLSGG  405


>gi|289445124|ref|ZP_06434868.1| PPE family protein [Mycobacterium tuberculosis CPHL_A]
 gi|289418082|gb|EFD15283.1| PPE family protein [Mycobacterium tuberculosis CPHL_A]
Length=285

 Score =  529 bits (1362),  Expect = 4e-148, Method: Compositional matrix adjust.
 Identities = 266/267 (99%), Positives = 267/267 (100%), Gaps = 0/267 (0%)

Query  1    MFMDFAMLPPEVNSTRMYSGPGAGSLWAAAAAWDQVSAELQSAAETYRSVIASLTGWQWL  60
            MFMDFAMLPPEVNSTRMYSGPGAGSLWAAAAAWDQVSAELQSAAETYRSVIASLTGWQWL
Sbjct  1    MFMDFAMLPPEVNSTRMYSGPGAGSLWAAAAAWDQVSAELQSAAETYRSVIASLTGWQWL  60

Query  61   GPSSVRMGAAVTPYVEWLTTTAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVL  120
            GPSSVRMGAAVTPYVEWLTTTAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVL
Sbjct  61   GPSSVRMGAAVTPYVEWLTTTAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVL  120

Query  121  SLIATNFFGQNTAAIAALETQYAEMWEQDATAMYDYAATSAAARTLTPFTSPQQDTNSAG  180
            SLIATNFFGQNTAAIAALETQYAEMWEQDATAMYDYAATSAAARTLTPFTSPQQDTNSAG
Sbjct  121  SLIATNFFGQNTAAIAALETQYAEMWEQDATAMYDYAATSAAARTLTPFTSPQQDTNSAG  180

Query  181  LPAQSAEVSRATANAGAADGNWLGNLLEEIGILLLPIAPELTPFFLEAGEIVNAIPFPSI  240
            LPAQSAEVSRATANAGAADGNWLGNLLEEIGILLLPIAPELTPFFLEAGEIVNAIPFPSI
Sbjct  181  LPAQSAEVSRATANAGAADGNWLGNLLEEIGILLLPIAPELTPFFLEAGEIVNAIPFPSI  240

Query  241  VGDEFCLLDGLLAWYATIGSINNINSM  267
            VGDEFCLLDGLLAWYATIGSINNINS+
Sbjct  241  VGDEFCLLDGLLAWYATIGSINNINSI  267


>gi|323717805|gb|EGB27002.1| hypothetical protein TMMG_00021 [Mycobacterium tuberculosis CDC1551A]
Length=262

 Score =  514 bits (1323),  Expect = 1e-143, Method: Compositional matrix adjust.
 Identities = 262/262 (100%), Positives = 262/262 (100%), Gaps = 0/262 (0%)

Query  145  MWEQDATAMYDYAATSAAARTLTPFTSPQQDTNSAGLPAQSAEVSRATANAGAADGNWLG  204
            MWEQDATAMYDYAATSAAARTLTPFTSPQQDTNSAGLPAQSAEVSRATANAGAADGNWLG
Sbjct  1    MWEQDATAMYDYAATSAAARTLTPFTSPQQDTNSAGLPAQSAEVSRATANAGAADGNWLG  60

Query  205  NLLEEIGILLLPIAPELTPFFLEAGEIVNAIPFPSIVGDEFCLLDGLLAWYATIGSINNI  264
            NLLEEIGILLLPIAPELTPFFLEAGEIVNAIPFPSIVGDEFCLLDGLLAWYATIGSINNI
Sbjct  61   NLLEEIGILLLPIAPELTPFFLEAGEIVNAIPFPSIVGDEFCLLDGLLAWYATIGSINNI  120

Query  265  NSMGTGIIGAEKNLGILPELGSAAAAAAPPPADIAPAFLAPLTSMAKSLSDGALRGPGEV  324
            NSMGTGIIGAEKNLGILPELGSAAAAAAPPPADIAPAFLAPLTSMAKSLSDGALRGPGEV
Sbjct  121  NSMGTGIIGAEKNLGILPELGSAAAAAAPPPADIAPAFLAPLTSMAKSLSDGALRGPGEV  180

Query  325  SAAMRGAGTIGQMSVPPAWKAPAVTTVRAFDATPMTTLPGGDAPAAGVPGLPGMPASGAG  384
            SAAMRGAGTIGQMSVPPAWKAPAVTTVRAFDATPMTTLPGGDAPAAGVPGLPGMPASGAG
Sbjct  181  SAAMRGAGTIGQMSVPPAWKAPAVTTVRAFDATPMTTLPGGDAPAAGVPGLPGMPASGAG  240

Query  385  RAGVVPRYGVRLTVMTRPLSGG  406
            RAGVVPRYGVRLTVMTRPLSGG
Sbjct  241  RAGVVPRYGVRLTVMTRPLSGG  262


>gi|240173322|ref|ZP_04751980.1| PPE family protein [Mycobacterium kansasii ATCC 12478]
Length=402

 Score =  452 bits (1163),  Expect = 5e-125, Method: Compositional matrix adjust.
 Identities = 264/409 (65%), Positives = 312/409 (77%), Gaps = 10/409 (2%)

Query  1    MFMDFAMLPPEVNSTRMYSGPGAGSLWAAAAAWDQVSAELQSAAETYRSVIASLTGWQWL  60
            MF DFA LPPEV STRMYSGPG+GSL AAA  W Q+SAEL ++A+TYRSV++ L  W W+
Sbjct  1    MFTDFAFLPPEVISTRMYSGPGSGSLQAAAEGWQQLSAELHASAQTYRSVVSDLIAWHWV  60

Query  61   GPSSVRMGAAVTPYVEWLTTTAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVL  120
            GPSS  M AA T Y EWL  TA Q  QTA Q   AA+ F++AFAMTVPP  + ANR Q+L
Sbjct  61   GPSSAAMAAAATSYAEWLEATAIQTGQTARQAATAASAFDEAFAMTVPPSIVFANREQLL  120

Query  121  SLIATNFFGQNTAAIAALETQYAEMWEQDATAMYDYAATSAAARTLTPFTSPQQDTNSAG  180
             LIATNFFGQNT+AIAALE  YAEMW  +++ M DY+ TSAAA  LTPF SPQQ TN AG
Sbjct  121  LLIATNFFGQNTSAIAALELAYAEMWVTNSSVMQDYSVTSAAATKLTPFASPQQATNPAG  180

Query  181  LPAQSAEVSRATANAGAADGNWLGNLLEEIGILLLPIAPELTPFFLEAGEIVNAIPFPSI  240
            LP Q+A V++ATA A A  GNWLGNLLE+IG+ LLP APELTPFFLEAGE++NAIPFPSI
Sbjct  181  LPGQAAAVAQATAGAAADGGNWLGNLLEQIGMALLPFAPELTPFFLEAGELINAIPFPSI  240

Query  241  VGDEFCLLDGLLAWYATIGSINNINSMGTGIIGAEKNLGILPELGSAAAAAAPPPADIAP  300
            V D+F  LDG++AWYAT+ SINNI+S+GTGIIGAEKNLGILP L       A P A++ P
Sbjct  241  VADDFTFLDGVMAWYATVSSINNISSLGTGIIGAEKNLGILPSL-------AAPAAEVVP  293

Query  301  AFLAPLTSMAKSLSDGALR---GPGEVSAAMRGAGTIGQMSVPPAWKAPAVTTVRAFDAT  357
            + LAPL +  K+++D   +   G GEV+AA RGAG+IG MSVPP W APAVTTV+ F  T
Sbjct  294  SELAPLVNSVKNVADAVAKGGPGIGEVTAAFRGAGSIGPMSVPPTWTAPAVTTVKTFQGT  353

Query  358  PMTTLPGGDAPAAGVPGLPGMPASGAGRAGVVPRYGVRLTVMTRPLSGG  406
            P+TTLP GDA  AG+PG+PG+  +G  R GVVPRYG+   VMTRPLSGG
Sbjct  354  PLTTLPAGDAGGAGMPGMPGIAPAGTRRGGVVPRYGLTPRVMTRPLSGG  402


>gi|183983433|ref|YP_001851724.1| PPE family protein, PPE61 [Mycobacterium marinum M]
 gi|183176759|gb|ACC41869.1| PPE family protein, PPE61 [Mycobacterium marinum M]
Length=391

 Score =  429 bits (1104),  Expect = 3e-118, Method: Compositional matrix adjust.
 Identities = 246/406 (61%), Positives = 294/406 (73%), Gaps = 17/406 (4%)

Query  3    MDFAMLPPEVNSTRMYSGPGAGSLWAAAAAWDQVSAELQSAAETYRSVIASLTGWQWLGP  62
            M F MLPPE+NSTRMY+GPG+ SL AA+A+W+ VS  L SAAE+YR++IA LT +QWLGP
Sbjct  1    MSFMMLPPEINSTRMYTGPGSASLRAASASWNSVSVGLHSAAESYRAMIADLTSFQWLGP  60

Query  63   SSVRMGAAVTPYVEWLTTTAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVLSL  122
            SS  M A+V PYV WL  TA QA  +A Q +AAA  +EQAFAMTVPPPAI  NRA++ +L
Sbjct  61   SSAAMIASVLPYVGWLEATAVQAGHSAMQASAAAAAYEQAFAMTVPPPAIAVNRAELAAL  120

Query  123  IATNFFGQNTAAIAALETQYAEMWEQDATAMYDYAATSAAARTLTPFTSPQQDTNSAGLP  182
            IATNFFGQNTAAIAA E +YAEMW  DATAM  Y++TSAAAR LTPFTSPQQ TN AGL 
Sbjct  121  IATNFFGQNTAAIAANEAEYAEMWATDATAMTSYSSTSAAARALTPFTSPQQTTNPAGLG  180

Query  183  AQSAEVSRATANAGAADGNWLGNLLEEIGILLLPIAPELTPFFLEAGEIVNAIPFPSIVG  242
            AQSA V+ +TAN  A  GNWLGNL++ IG+ LLPIAPEL+   +  GE++N IPFPS   
Sbjct  181  AQSAAVANSTANVAADSGNWLGNLIDAIGVALLPIAPELSAILIPLGELINMIPFPSFFA  240

Query  243  DEFCLLDGLLAWYATIGSINNINSMGTGIIGAEKNLGILPELGSAAAAAAPPPADIA--P  300
            D+F +LDGLLA+YATIGSI NI SMG+GIIG E  LG++P   +A AAA    A +   P
Sbjct  241  DDFTILDGLLAFYATIGSIKNIQSMGSGIIGTENTLGLIPHAAAATAAAPNALAALGGEP  300

Query  301  AFLAPLTSMAKSLSDGALRGPGEVSAAMRGAGTIGQMSVPPAWKAPAVTTVRAFDATPMT  360
            A  A L  +A  L+ G                 IGQMSVPP+W  P VTT++A  ATP+T
Sbjct  301  ALGAELGPIAAELTSG---------------NRIGQMSVPPSWTEPKVTTIKALQATPLT  345

Query  361  TLPGGDAPAAGVPGLPGMPASGAGRAGVVPRYGVRLTVMTRPLSGG  406
            TLP  + PA+G+PG+PGM  +G GR GV PRYGVRLTVM RP SGG
Sbjct  346  TLPTDEVPASGIPGIPGMAMTGTGRGGVTPRYGVRLTVMPRPFSGG  391


>gi|183983432|ref|YP_001851723.1| PPE family protein, PPE61_1 [Mycobacterium marinum M]
 gi|183176758|gb|ACC41868.1| PPE family protein, PPE61_1 [Mycobacterium marinum M]
Length=391

 Score =  426 bits (1096),  Expect = 3e-117, Method: Compositional matrix adjust.
 Identities = 242/404 (60%), Positives = 294/404 (73%), Gaps = 13/404 (3%)

Query  3    MDFAMLPPEVNSTRMYSGPGAGSLWAAAAAWDQVSAELQSAAETYRSVIASLTGWQWLGP  62
            M F MLPPE+NSTRMYSGPG+ SL AA+A+W+ VS  L SAAE+YR++IA LT +QWLGP
Sbjct  1    MSFMMLPPEINSTRMYSGPGSASLRAASASWNSVSVGLHSAAESYRAMIADLTSFQWLGP  60

Query  63   SSVRMGAAVTPYVEWLTTTAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVLSL  122
            SS  M A+V PYV WL  TA QA  +A Q +AAA  +EQAFAMTVPPPAI  NRA++ +L
Sbjct  61   SSAAMVASVLPYVGWLEATAVQAGHSAMQASAAAAAYEQAFAMTVPPPAIAVNRAELAAL  120

Query  123  IATNFFGQNTAAIAALETQYAEMWEQDATAMYDYAATSAAARTLTPFTSPQQDTNSAGLP  182
            IATNFFGQNTAAIAA E +YAEMW  DATAM  Y++TSAAAR LTPFTSP Q TN AGL 
Sbjct  121  IATNFFGQNTAAIAANEAEYAEMWATDATAMTSYSSTSAAARALTPFTSPHQTTNPAGLG  180

Query  183  AQSAEVSRATANAGAADGNWLGNLLEEIGILLLPIAPELTPFFLEAGEIVNAIPFPSIVG  242
            AQSA V+ +TAN  A  GNWLGNL++ IG+ LLPIAPEL+   +  GE++N IPFPS + 
Sbjct  181  AQSAAVANSTANVAADSGNWLGNLIDAIGVALLPIAPELSAILIPLGELINMIPFPSFLA  240

Query  243  DEFCLLDGLLAWYATIGSINNINSMGTGIIGAEKNLGILPELGSAAAAAAPPPADIAPAF  302
            D+F +LDGLLA+YATIGS+ NI SM +GIIG +  LG++P   +AAA A           
Sbjct  241  DDFTILDGLLAFYATIGSMQNIQSMASGIIGTDDTLGLIPHAAAAAADAP----------  290

Query  303  LAPLTSMAKSLSDGALRGPGEVSAAMRGAGTIGQMSVPPAWKAPAVTTVRAFDATPMTTL  362
               L ++      GA  GP  ++A +     IGQMSVPP+W  P VTT++A  ATP+TTL
Sbjct  291  -NALAALGGEPGLGAELGP--IAAELTSGNRIGQMSVPPSWTEPKVTTIKALQATPLTTL  347

Query  363  PGGDAPAAGVPGLPGMPASGAGRAGVVPRYGVRLTVMTRPLSGG  406
            P  + PA+G+PG+PGM  +G GR GV PRYGVRLTVMTRP SGG
Sbjct  348  PTDEVPASGIPGMPGMAMTGTGRGGVAPRYGVRLTVMTRPFSGG  391


>gi|240169296|ref|ZP_04747955.1| PPE family protein [Mycobacterium kansasii ATCC 12478]
Length=409

 Score =  412 bits (1060),  Expect = 4e-113, Method: Compositional matrix adjust.
 Identities = 240/413 (59%), Positives = 286/413 (70%), Gaps = 11/413 (2%)

Query  1    MFMDFAMLPPEVNSTRMYSGPGAGSLWAAAAAWDQVSAELQSAAETYRSVIASLTGWQWL  60
            MF DFA+LPPEVNS RMY+GPG+ SL  AAA+W  ++ EL SAA  YRSV+  LT  QW 
Sbjct  1    MF-DFALLPPEVNSARMYTGPGSASLRTAAASWQLLAVELHSAASMYRSVVMDLTSMQWT  59

Query  61   GPSSVRMGAAVTPYVEWLTTTAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVL  120
            G SS+ M AAV PYV+WLT TA QA  TA Q TAAAT FEQAFAMTVPPP I ANRA++L
Sbjct  60   GSSSMSMAAAVIPYVDWLTVTAEQAGHTAAQATAAATAFEQAFAMTVPPPLIAANRAELL  119

Query  121  SLIATNFFGQNTAAIAALETQYAEMWEQDATAMYDYAATSAAARTLTPFTSPQQDTNSAG  180
            +LIATNFFGQNTAAIA  E QY +MW QDATAM DY   SAAA  LTPF SPQ DTN AG
Sbjct  120  ALIATNFFGQNTAAIATTEAQYMQMWAQDATAMDDYTVASAAAWKLTPFASPQPDTNPAG  179

Query  181  LPAQSAEVSRATANAGAADGNWLGNLLEEIGILLLPIA-PELTPFFLEAGEIVNAIPFPS  239
              AQ A V+RA   A    GNW+GNLL++IG  L  +  PE+       GE VN +  P 
Sbjct  180  RSAQHAAVTRAITKAPDNKGNWIGNLLKDIGAALTAVGLPEVGVPLYALGEFVNTLKLPK  239

Query  240  IVGDEFCLLDGLLAWYATIGSINNINSMGTGIIGAEKNLGILPELGSAAAAAAPPPADIA  299
            I+ D+F  LD L AWY+T+GS+  ++ M  GII  EK+LG++  +    A   P    +A
Sbjct  240  ILKDDFTALDALFAWYSTMGSVTGVSGMTNGIINTEKSLGLISGVTQPVAETVP---KVA  296

Query  300  PAFLAPLTSMAKSLSDGALRG----PGEVSAAMRGAGTIGQMSVPPAWKAP-AVTTVRAF  354
            PA LAPL S+AKSLS   +R      G+VSAA R AG+IGQ+SVPP+W  P A    + F
Sbjct  297  PALLAPLNSIAKSLSGATMRAGGVLGGQVSAAARSAGSIGQLSVPPSWATPQAAVAAKTF  356

Query  355  D-ATPMTTLPGGDAPAAGVPGLPGMPASGAGRAGVVPRYGVRLTVMTRPLSGG  406
              ATP+TTLP  DA  A +PGLPGMP++  GRAGVVPRYG+R+TVM+RPLSGG
Sbjct  357  QAATPLTTLPTSDAAPAAMPGLPGMPSAATGRAGVVPRYGLRMTVMSRPLSGG  409


>gi|118618170|ref|YP_906502.1| PPE family protein [Mycobacterium ulcerans Agy99]
 gi|118570280|gb|ABL05031.1| PPE family protein [Mycobacterium ulcerans Agy99]
Length=377

 Score =  399 bits (1024),  Expect = 6e-109, Method: Compositional matrix adjust.
 Identities = 227/390 (59%), Positives = 282/390 (73%), Gaps = 13/390 (3%)

Query  17   MYSGPGAGSLWAAAAAWDQVSAELQSAAETYRSVIASLTGWQWLGPSSVRMGAAVTPYVE  76
            MY+GPG+ SL AA+A+W+ VS  L SAAE+YR++IA LT +QWLGPSS  M A+V PYV 
Sbjct  1    MYTGPGSASLRAASASWNGVSVGLHSAAESYRAMIADLTSFQWLGPSSAAMVASVLPYVG  60

Query  77   WLTTTAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVLSLIATNFFGQNTAAIA  136
            WL  TA QA  +A Q +AAA  +EQAFAMTVPPPAI  NRA++ +LIAT+FFGQNTAAIA
Sbjct  61   WLEATAVQAGHSAMQASAAAAAYEQAFAMTVPPPAIAVNRAELAALIATDFFGQNTAAIA  120

Query  137  ALETQYAEMWEQDATAMYDYAATSAAARTLTPFTSPQQDTNSAGLPAQSAEVSRATANAG  196
            A E +YAEMW  DATAM  Y++TSAAAR LTPF+SP Q TN AGL AQSA V+ +TAN  
Sbjct  121  ANEAEYAEMWATDATAMTSYSSTSAAARALTPFSSPHQTTNPAGLGAQSAAVAHSTANVA  180

Query  197  AADGNWLGNLLEEIGILLLPIAPELTPFFLEAGEIVNAIPFPSIVGDEFCLLDGLLAWYA  256
            A  GNWLGNL++ IG+ LLPIAPEL+   +  GE++N IPFPS + D+F +LDGLLA+YA
Sbjct  181  ADSGNWLGNLIDAIGVALLPIAPELSAILIPLGELINMIPFPSFLADDFTVLDGLLAFYA  240

Query  257  TIGSINNINSMGTGIIGAEKNLGILPELGSAAAAAAPPPADIAPAFLAPLTSMAKSLSDG  316
            TIGS+ NI SMG+GIIG +  LG++P   +A A A              L ++    + G
Sbjct  241  TIGSMQNIQSMGSGIIGTDDTLGLIPHAAAATADAP-----------NALAALGGEPALG  289

Query  317  ALRGPGEVSAAMRGAGTIGQMSVPPAWKAPAVTTVRAFDATPMTTLPGGDAPAAGVPGLP  376
            A  GP  ++A +     IGQMSVPP+W  P VTT++A  ATP+TTLP  + PA+G+PG+P
Sbjct  290  AELGP--IAAELTSGNRIGQMSVPPSWTDPKVTTIKALQATPLTTLPTDEVPASGIPGMP  347

Query  377  GMPASGAGRAGVVPRYGVRLTVMTRPLSGG  406
            GM  +G GR GV PRYGVRLTVM RP SGG
Sbjct  348  GMAMTGTGRGGVAPRYGVRLTVMPRPFSGG  377


>gi|183980225|ref|YP_001848516.1| PPE family protein, PPE51_2 [Mycobacterium marinum M]
 gi|183173551|gb|ACC38661.1| PPE family protein, PPE51_2 [Mycobacterium marinum M]
Length=381

 Score =  366 bits (940),  Expect = 3e-99, Method: Compositional matrix adjust.
 Identities = 213/406 (53%), Positives = 271/406 (67%), Gaps = 27/406 (6%)

Query  3    MDFAMLPPEVNSTRMYSGPGAGSLWAAAAAWDQVSAELQSAAETYRSVIASLTGWQWLGP  62
            MDFAMLPPEVNS  MY+GPGAGSL AAA +WD+++ EL + A+TY SV++ LT   W GP
Sbjct  1    MDFAMLPPEVNSGLMYTGPGAGSLLAAANSWDELAIELGTTAQTYESVLSGLTSMYWAGP  60

Query  63   SSVRMGAAVTPYVEWLTTTAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVLSL  122
            +S  M A   PYV WL +TA Q +QTATQ  AAA  FEQA+AMTVPPP I+ANR Q++SL
Sbjct  61   ASESMAAKAAPYVWWLHSTAEQTQQTATQCRAAAMAFEQAYAMTVPPPVILANRMQLMSL  120

Query  123  IATNFFGQNTAAIAALETQYAEMWEQDATAMYDYAATSAAARTLTPFTSPQQDTNSAGLP  182
            +ATNFFGQNTAAIAALE QYAEMWEQDA AMY YA ++A A  L PF+SPQQ TN AGL 
Sbjct  121  VATNFFGQNTAAIAALEAQYAEMWEQDAAAMYGYATSAAMAAQLVPFSSPQQTTNPAGLS  180

Query  183  AQSAEVSRATANAGAADGNWLGNLLEEIGILLLPIAPELTPFFLEAGEIVNAIPFPSIVG  242
            AQSA V++A A A AA  N L +L+                  ++ G    A  FP+++ 
Sbjct  181  AQSAAVNQADATAAAA--NPLSDLIA----------------LVQKGLAALAGAFPNLLP  222

Query  243  DEFCLLDGLLAWYATIGSINNINSMGTGIIGAEKNLGILPELGSAAAAAAPPPADIAPAF  302
            D+F +LDG+ A YAT+G   +  S+  GIIGAE NLG+L        AA+  PA++AP  
Sbjct  223  DDFSILDGIFAGYATVGVSQDCESIIAGIIGAESNLGML-------GAASENPAELAPGD  275

Query  303  LAPLTSMAKSLS-DGALRGPGEVSAAMRGAGTIGQMSVPPAWKAPAVTTVRAFDATPMTT  361
            +   + ++ + S  GA+ GPG V  ++  AG+IGQ+SVP +W APA   V A  +  +TT
Sbjct  276  IGIGSVLSSAPSVGGAVSGPGAVLVSVGRAGSIGQLSVPASWAAPATRQVAALSSAGLTT  335

Query  362  LPGGDAPAAGVPGLPGMPASGAGRA-GVVPRYGVRLTVMTRPLSGG  406
            +PG +  A G+PG+PGMP   + RA  VVPRYGVRLTVM  P + G
Sbjct  336  IPGTEEAAHGIPGMPGMPVGSSSRASSVVPRYGVRLTVMAHPPAAG  381


>gi|240168615|ref|ZP_04747274.1| PPE family protein [Mycobacterium kansasii ATCC 12478]
Length=379

 Score =  316 bits (809),  Expect = 5e-84, Method: Compositional matrix adjust.
 Identities = 203/411 (50%), Positives = 258/411 (63%), Gaps = 39/411 (9%)

Query  3    MDFAMLPPEVNSTRMYSGPGAGSLWAAAAAWDQVSAELQSAAETYRSVIASLTGWQWLGP  62
            MD+A LPPE+NS R+YSGPG GSL AAA  WD V+ EL SAA  YRSVI+SLT   W GP
Sbjct  1    MDYAFLPPEINSARIYSGPGPGSLLAAARGWDAVATELTSAAVGYRSVISSLTAMYWWGP  60

Query  63   SSVRMGAAVTPYVEWLTTTAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVLSL  122
            +SV M A   P+VEWL TTAAQA+++A Q  AAA  FEQA AMTVPP  + ANR Q+ +L
Sbjct  61   ASVSMLATAGPFVEWLETTAAQAKESADQSRAAAAAFEQAHAMTVPPAVVAANRTQLKAL  120

Query  123  IATNFFGQNTAAIAALETQYAEMWEQDATAMYDYAATSAAARTLTPFTSPQQDTNSAGLP  182
            IA+NFFGQNTAAIAA E QYAEMW QDA AMY YA+ SAAA  LTPF+SP+   +  G  
Sbjct  121  IASNFFGQNTAAIAATEAQYAEMWAQDAAAMYGYASNSAAATALTPFSSPELSVDPDG--  178

Query  183  AQSAEVSRATANAGAADGN------WLGNLLEEIGILLLPIAPELTPFFLEAGEIVNAIP  236
              +   + + A  G + GN      WL +L           APE     L+A +      
Sbjct  179  VVAQSAAVSQAAGGGSAGNTATVLSWLASL-----------APEA----LQAVQ-----D  218

Query  237  FPSIVGDEFCLLDGLLAWYATIGSINNINSMGTGIIGAEKNLGILPELGSAAAAAAPPPA  296
            +P+I+ D+F +LD + A YAT+G   ++ S   GIIGAE NLG+              PA
Sbjct  219  WPNILPDDFTILDAIFAVYATVGVSQDVESFAAGIIGAEDNLGLF--------GTTENPA  270

Query  297  DIAPAFLAPLTSMAKSLSDGALRGPGEVSAAMRGAGTIGQMSVPPAWKAPAVTTVRAFDA  356
            ++ PA L+P+ S A+S +   L     V+A+M  AG+IG +SVP +W AP+   V A   
Sbjct  271  ELLPAGLSPVFSAAESSTGAGLS--SVVTASMSRAGSIGPLSVPASWTAPSTGPVTALSG  328

Query  357  TPMTTLPGGDAPAAGVPGLPGMPASGAGRA-GVVPRYGVRLTVMTRPLSGG  406
            + +TT+PG + P  G+PG+PGMPA    RA  VVPRYGVRLTVM+RP + G
Sbjct  329  SGLTTIPGTEVPDHGLPGVPGMPAGTLKRASSVVPRYGVRLTVMSRPPAAG  379


>gi|31794311|ref|NP_856804.1| PPE family protein [Mycobacterium bovis AF2122/97]
 gi|31619907|emb|CAD95251.1| PPE FAMILY PROTEIN [Mycobacterium bovis AF2122/97]
 gi|341603057|emb|CCC65735.1| PPE family protein [Mycobacterium bovis BCG str. Moreau RDJ]
Length=381

 Score =  309 bits (791),  Expect = 6e-82, Method: Compositional matrix adjust.
 Identities = 217/412 (53%), Positives = 263/412 (64%), Gaps = 39/412 (9%)

Query  3    MDFAMLPPEVNSTRMYSGPGAGSLWAAAAAWDQVSAELQSAAETYRSVIASLTGWQWLGP  62
            MD+A LPPE+NS RMYSGPG  S+  AAA+WD ++AEL SAAE Y SVIA LTG  W GP
Sbjct  1    MDYAFLPPEINSARMYSGPGPNSMLVAAASWDALAAELASAAENYGSVIARLTGMHWWGP  60

Query  63   SSVRMGAAVTPYVEWLTTTAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVLSL  122
            +S  M A   PYVEWL  TAAQ +QTATQ  AAA  FEQA AMTVPP  + ANRA++ +L
Sbjct  61   ASTSMLAMSAPYVEWLERTAAQTKQTATQARAAAAAFEQAHAMTVPPALVTANRAELKAL  120

Query  123  IATNFFGQNTAAIAALETQYAEMWEQDATAMYDYAATSAAARTLTPFTSPQQDTNSAGLP  182
            IA+N  GQNTAAIAA+E QYAEMW QDA AMY YA TSAAAR LTPF+SPQQ TN AGL 
Sbjct  121  IASNLLGQNTAAIAAIEAQYAEMWAQDAAAMYGYATTSAAARQLTPFSSPQQTTNPAGLA  180

Query  183  AQSAEVSRATANAGAADGNWLGNLLEEIGILLLPIAPELTPFFLEAGEIVNAIPFPSIVG  242
            AQ+A V++A  N+        GN    +         +L+ F  +A E      +P+I+ 
Sbjct  181  AQNAAVTQAATNSA-------GNTPTALS--------QLSSFLSQAVEAPTG--WPNILP  223

Query  243  DEFCLLDGLLAWYATIGSINNINSMGTGIIGAEKNLGILPELGSAAAAAAPPPADIAPAF  302
            D+F +LDG+LA YAT+G   +I S+  GIIGAE NLG+L        AA+  PA++AP  
Sbjct  224  DDFTILDGILAAYATVGVTQDIESICAGIIGAENNLGLL-------GAASENPAELAPGA  276

Query  303  L---APLTSMAK----SLSDGALRGPGEVSAAMRGAGTIGQMSVPPAWKAPAVTTVRAFD  355
                A L+S  K    S+ D  L   G        AG+IG MSVPP+W  P+ T V A  
Sbjct  277  FGIDAALSSAEKGAAASMHDAVLASAGR-------AGSIGPMSVPPSWATPSSTPVSALS  329

Query  356  ATPMTTLPGGDAPAAGVPGLPGMPASGAGRA-GVVPRYGVRLTVMTRPLSGG  406
               +TTL G D    G PGLPG+PA    RA GV+PRYGVRLTVM+RP + G
Sbjct  330  GAGLTTLDGTDVAEHGTPGLPGVPAGTDKRASGVIPRYGVRLTVMSRPPAAG  381


>gi|121639018|ref|YP_979242.1| PPE family protein [Mycobacterium bovis BCG str. Pasteur 1173P2]
 gi|121494666|emb|CAL73147.1| PPE family protein [Mycobacterium bovis BCG str. Pasteur 1173P2]
Length=381

 Score =  308 bits (789),  Expect = 1e-81, Method: Compositional matrix adjust.
 Identities = 216/412 (53%), Positives = 263/412 (64%), Gaps = 39/412 (9%)

Query  3    MDFAMLPPEVNSTRMYSGPGAGSLWAAAAAWDQVSAELQSAAETYRSVIASLTGWQWLGP  62
            MD+A LPPE+NS RMYSGPG  S+  AAA+WD ++AEL SAAE Y SVIA LTG  W GP
Sbjct  1    MDYAFLPPEINSARMYSGPGPNSMLVAAASWDALAAELASAAENYGSVIARLTGMHWWGP  60

Query  63   SSVRMGAAVTPYVEWLTTTAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVLSL  122
            +S  M A   PYVEWL  TAAQ +QTATQ  AAA  FEQA AMTVPP  + ANRA++ +L
Sbjct  61   ASTSMLAMSAPYVEWLERTAAQTKQTATQARAAAAAFEQAHAMTVPPALVTANRAELKAL  120

Query  123  IATNFFGQNTAAIAALETQYAEMWEQDATAMYDYAATSAAARTLTPFTSPQQDTNSAGLP  182
            IA+N  GQNTAAIAA+E QYAEMW QDA AMY YA TSAAAR LTPF+SPQQ TN AGL 
Sbjct  121  IASNLLGQNTAAIAAIEAQYAEMWAQDAAAMYGYATTSAAARQLTPFSSPQQTTNPAGLA  180

Query  183  AQSAEVSRATANAGAADGNWLGNLLEEIGILLLPIAPELTPFFLEAGEIVNAIPFPSIVG  242
            AQ+A V++A  N+        GN    +         +L+ F  +A  +     +P+I+ 
Sbjct  181  AQNAAVTQAATNSA-------GNTPTALS--------QLSSFLSQA--VKAPTGWPNILP  223

Query  243  DEFCLLDGLLAWYATIGSINNINSMGTGIIGAEKNLGILPELGSAAAAAAPPPADIAPAF  302
            D+F +LDG+LA YAT+G   +I S+  GIIGAE NLG+L        AA+  PA++AP  
Sbjct  224  DDFTILDGILAAYATVGVTQDIESICAGIIGAENNLGLL-------GAASENPAELAPGA  276

Query  303  L---APLTSMAK----SLSDGALRGPGEVSAAMRGAGTIGQMSVPPAWKAPAVTTVRAFD  355
                A L+S  K    S+ D  L   G        AG+IG MSVPP+W  P+ T V A  
Sbjct  277  FGIDAALSSAEKGAAASMHDAVLASAGR-------AGSIGPMSVPPSWATPSSTPVSALS  329

Query  356  ATPMTTLPGGDAPAAGVPGLPGMPASGAGRA-GVVPRYGVRLTVMTRPLSGG  406
               +TTL G D    G PGLPG+PA    RA GV+PRYGVRLTVM+RP + G
Sbjct  330  GAGLTTLDGTDVAEHGTPGLPGVPAGTDKRASGVIPRYGVRLTVMSRPPAAG  381


>gi|340628111|ref|YP_004746563.1| ppe family protein [Mycobacterium canettii CIPT 140010059]
 gi|340006301|emb|CCC45480.1| ppe family protein [Mycobacterium canettii CIPT 140010059]
Length=381

 Score =  307 bits (787),  Expect = 2e-81, Method: Compositional matrix adjust.
 Identities = 216/412 (53%), Positives = 262/412 (64%), Gaps = 39/412 (9%)

Query  3    MDFAMLPPEVNSTRMYSGPGAGSLWAAAAAWDQVSAELQSAAETYRSVIASLTGWQWLGP  62
            MD+A LPPE+NS RMYSGPG  S+  AAA+WD ++AEL SAAE Y SVIA LTG  W GP
Sbjct  1    MDYAFLPPEINSARMYSGPGPNSMLVAAASWDALAAELASAAENYGSVIARLTGMHWWGP  60

Query  63   SSVRMGAAVTPYVEWLTTTAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVLSL  122
            +S  M A   PYVEWL  TAAQ +QTATQ  AAA  FEQA AMTVPP  + ANRA++ +L
Sbjct  61   ASTSMLAMSAPYVEWLERTAAQTKQTATQARAAAAAFEQAHAMTVPPALVTANRAELKAL  120

Query  123  IATNFFGQNTAAIAALETQYAEMWEQDATAMYDYAATSAAARTLTPFTSPQQDTNSAGLP  182
            IA+N  GQNTAAIAA+E QYAEMW QDA AMY YA TSAAAR LTPF+SPQQ TN AGL 
Sbjct  121  IASNLLGQNTAAIAAIEAQYAEMWAQDAAAMYGYATTSAAARQLTPFSSPQQTTNPAGLA  180

Query  183  AQSAEVSRATANAGAADGNWLGNLLEEIGILLLPIAPELTPFFLEAGEIVNAIPFPSIVG  242
            AQ+A V++A  N+        GN    +         +L+ F  +A E      +P+I+ 
Sbjct  181  AQNAAVTQAATNSA-------GNTPTALS--------QLSSFLSQAVEAPTG--WPNILP  223

Query  243  DEFCLLDGLLAWYATIGSINNINSMGTGIIGAEKNLGILPELGSAAAAAAPPPADIAPAF  302
            D+F +LDG+ A YAT+G   +I S+  GIIGAE NLG+L        AA+  PA++AP  
Sbjct  224  DDFTILDGIFAAYATVGVTQDIESICAGIIGAENNLGLL-------GAASENPAELAPGA  276

Query  303  L---APLTSMAK----SLSDGALRGPGEVSAAMRGAGTIGQMSVPPAWKAPAVTTVRAFD  355
                A L+S  K    S+ D  L   G        AG+IG MSVPP+W  P+ T V A  
Sbjct  277  FGIDAALSSAEKGAAASMHDAVLASAGR-------AGSIGPMSVPPSWATPSSTPVSALS  329

Query  356  ATPMTTLPGGDAPAAGVPGLPGMPASGAGRA-GVVPRYGVRLTVMTRPLSGG  406
               +TTL G D    G PGLPG+PA    RA GV+PRYGVRLTVM+RP + G
Sbjct  330  GAGLTTLDGTDVAEHGTPGLPGVPAGTDKRASGVIPRYGVRLTVMSRPPAAG  381


>gi|183981528|ref|YP_001849819.1| PPE family protein, PPE51 [Mycobacterium marinum M]
 gi|183174854|gb|ACC39964.1| PPE family protein, PPE51 [Mycobacterium marinum M]
Length=382

 Score =  306 bits (783),  Expect = 5e-81, Method: Compositional matrix adjust.
 Identities = 209/406 (52%), Positives = 262/406 (65%), Gaps = 26/406 (6%)

Query  3    MDFAMLPPEVNSTRMYSGPGAGSLWAAAAAWDQVSAELQSAAETYRSVIASLTGWQWLGP  62
            MDF++LPPEVNS RMY+GPG+GSL AAAA+WD ++AEL + AET  S++  LT   W GP
Sbjct  1    MDFSLLPPEVNSARMYTGPGSGSLLAAAASWDALAAELGTTAETCGSILTGLTDLSWRGP  60

Query  63   SSVRMGAAVTPYVEWLTTTAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVLSL  122
            +S  M A+  PYV WL  TA Q +Q A Q   AA  FEQA+AMTVPPP + ANRAQ+L L
Sbjct  61   ASESMAASAAPYVGWLYRTAEQTQQAAIQARTAALAFEQAYAMTVPPPLVAANRAQLLVL  120

Query  123  IATNFFGQNTAAIAALETQYAEMWEQDATAMYDYAATSAAARTLTPFTSPQQDTNSAGLP  182
            IATNFFGQNT+AIAA E QYAEMW QDA AMY YA TSAAA  LTPF+SP Q T+ AGL 
Sbjct  121  IATNFFGQNTSAIAANEAQYAEMWAQDAAAMYGYATTSAAAGMLTPFSSPNQATSPAGLA  180

Query  183  AQSAEVSRATANAGAADGNWLGNLLEEIGILLLPIAPELTPFFLEAGEIVNAIPFPSIVG  242
            AQS  V++A A A A D                PI  +L     ++   + AI  PSI+ 
Sbjct  181  AQSTAVTQANATAAATD----------------PIT-QLVSSLTQSLGAIQAI--PSILP  221

Query  243  DEFCLLDGLLAWYATIGSINNINSMGTGIIGAEKNLGILPELGSAAAAAAPPPADIAPAF  302
            D+F +LDG+ + YAT+G   +I S   G+IGAE NLG+   +GS+   A   P+D     
Sbjct  222  DDFTILDGVFSAYATVGVTQDIESFCAGVIGAENNLGL---IGSSENPAEVTPSDFGLGS  278

Query  303  LAPLTSMAKSLSDGALRGPGEVSAAMRGAGTIGQMSVPPAWKAPAVTTVRAFDATPMTTL  362
            L   T+ A + S G L     V+A++  +G+IGQ+SVPP+W AP+   V A   + +TT+
Sbjct  279  LISSTAPASAASGGGLG--SAVAASVGRSGSIGQLSVPPSWSAPSARMVSALSPSGLTTI  336

Query  363  PGG-DAPAAGVPGLPGMPASGAGRA-GVVPRYGVRLTVMTRPLSGG  406
            PG  +A AAG PG PGM A  A RA GV+PRYGVRLTVM  P + G
Sbjct  337  PGTEEAAAAGSPGFPGMVAPPATRASGVLPRYGVRLTVMAHPPAAG  382


>gi|224991510|ref|YP_002646199.1| PPE family protein [Mycobacterium bovis BCG str. Tokyo 172]
 gi|224774625|dbj|BAH27431.1| PPE family protein [Mycobacterium bovis BCG str. Tokyo 172]
Length=381

 Score =  306 bits (783),  Expect = 6e-81, Method: Compositional matrix adjust.
 Identities = 216/412 (53%), Positives = 262/412 (64%), Gaps = 39/412 (9%)

Query  3    MDFAMLPPEVNSTRMYSGPGAGSLWAAAAAWDQVSAELQSAAETYRSVIASLTGWQWLGP  62
            MD+A LPPE+NS RMYSGPG  S+  AAA+WD ++AEL SAAE Y SVIA LTG  W GP
Sbjct  1    MDYAFLPPEINSARMYSGPGPNSMLVAAASWDALAAELASAAENYGSVIARLTGMHWWGP  60

Query  63   SSVRMGAAVTPYVEWLTTTAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVLSL  122
            +S  M A   PYVEWL  TAAQ +QTATQ  AAA  FEQA AMTVPP  + ANRA++ +L
Sbjct  61   ASTSMLAMSAPYVEWLERTAAQTKQTATQARAAAAAFEQAHAMTVPPALVTANRAELKAL  120

Query  123  IATNFFGQNTAAIAALETQYAEMWEQDATAMYDYAATSAAARTLTPFTSPQQDTNSAGLP  182
            IA+N  GQNTAAIAA+E QYAEMW QDA AMY YA TSAAAR LTPF+SPQQ TN AGL 
Sbjct  121  IASNLLGQNTAAIAAIEAQYAEMWAQDAAAMYGYATTSAAARQLTPFSSPQQTTNPAGLA  180

Query  183  AQSAEVSRATANAGAADGNWLGNLLEEIGILLLPIAPELTPFFLEAGEIVNAIPFPSIVG  242
            AQ+A V++A  N+        GN    +         +L+ F  +A E      +P+I+ 
Sbjct  181  AQNAAVTQAATNSA-------GNTPTALS--------QLSSFLSQAVEAPTG--WPNILP  223

Query  243  DEFCLLDGLLAWYATIGSINNINSMGTGIIGAEKNLGILPELGSAAAAAAPPPADIAPAF  302
            D+F +LDG+LA YAT+G   +I S+  GIIGA  NLG+L        AA+  PA++AP  
Sbjct  224  DDFTILDGILAAYATVGVTQDIESICAGIIGAGNNLGLL-------GAASENPAELAPGA  276

Query  303  L---APLTSMAK----SLSDGALRGPGEVSAAMRGAGTIGQMSVPPAWKAPAVTTVRAFD  355
                A L+S  K    S+ D  L   G        AG+IG MSVPP+W  P+ T V A  
Sbjct  277  FGIDAALSSAEKGAAASMHDAVLASAGR-------AGSIGPMSVPPSWATPSSTPVSALS  329

Query  356  ATPMTTLPGGDAPAAGVPGLPGMPASGAGRA-GVVPRYGVRLTVMTRPLSGG  406
               +TTL G D    G PGLPG+PA    RA GV+PRYGVRLTVM+RP + G
Sbjct  330  GAGLTTLDGTDVAEHGTPGLPGVPAGTDKRASGVIPRYGVRLTVMSRPPAAG  381


>gi|118617919|ref|YP_906251.1| PPE family protein [Mycobacterium ulcerans Agy99]
 gi|118570029|gb|ABL04780.1| PPE family protein [Mycobacterium ulcerans Agy99]
Length=382

 Score =  303 bits (775),  Expect = 5e-80, Method: Compositional matrix adjust.
 Identities = 208/406 (52%), Positives = 261/406 (65%), Gaps = 26/406 (6%)

Query  3    MDFAMLPPEVNSTRMYSGPGAGSLWAAAAAWDQVSAELQSAAETYRSVIASLTGWQWLGP  62
            MDF++LPPEVNS RMY+GPG+GSL AAAA+WD ++AEL + AET  S++  LT   W GP
Sbjct  1    MDFSLLPPEVNSARMYTGPGSGSLLAAAASWDALAAELGTTAETCGSILTGLTDLSWRGP  60

Query  63   SSVRMGAAVTPYVEWLTTTAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVLSL  122
            +S  M A+  P V WL  TA Q +Q A Q   AA  FEQA+AMTVPPP + ANRAQ+L L
Sbjct  61   ASESMAASAAPCVGWLYRTAEQTQQAAIQARTAALAFEQAYAMTVPPPLVAANRAQLLVL  120

Query  123  IATNFFGQNTAAIAALETQYAEMWEQDATAMYDYAATSAAARTLTPFTSPQQDTNSAGLP  182
            IATNFFGQNT+AIAA E QYAEMW QDA AMY YA TSAAA  LTPF+SP Q T+ AGL 
Sbjct  121  IATNFFGQNTSAIAANEAQYAEMWAQDAAAMYGYATTSAAAGMLTPFSSPNQATSPAGLA  180

Query  183  AQSAEVSRATANAGAADGNWLGNLLEEIGILLLPIAPELTPFFLEAGEIVNAIPFPSIVG  242
            AQS  V++A A A A D                PI  +L     ++   + AI  PSI+ 
Sbjct  181  AQSTAVTQANATAAATD----------------PIT-QLVSSLTQSLGAIQAI--PSILP  221

Query  243  DEFCLLDGLLAWYATIGSINNINSMGTGIIGAEKNLGILPELGSAAAAAAPPPADIAPAF  302
            D+F +LDG+ + YAT+G   +I S   G+IGAE NLG+   +GS+   A   P+D     
Sbjct  222  DDFTILDGVFSAYATVGVTQDIESFCAGVIGAENNLGL---IGSSENPAEVTPSDFGLGS  278

Query  303  LAPLTSMAKSLSDGALRGPGEVSAAMRGAGTIGQMSVPPAWKAPAVTTVRAFDATPMTTL  362
            L   T+ A + S G L     V+A++  +G+IGQ+SVPP+W AP+   V A   + +TT+
Sbjct  279  LISSTAPASAASGGGLG--SAVAASVGRSGSIGQLSVPPSWSAPSARMVSALSPSGLTTI  336

Query  363  PGG-DAPAAGVPGLPGMPASGAGRA-GVVPRYGVRLTVMTRPLSGG  406
            PG  +A AAG PG PGM A  A RA GV+PRYGVRLTVM  P + G
Sbjct  337  PGTEEAAAAGSPGFPGMVAPPATRASGVLPRYGVRLTVMAHPPAAG  382


>gi|340628112|ref|YP_004746564.1| PPE family protein [Mycobacterium canettii CIPT 140010059]
 gi|340006302|emb|CCC45481.1| PPE family protein [Mycobacterium canettii CIPT 140010059]
Length=380

 Score =  298 bits (764),  Expect = 8e-79, Method: Compositional matrix adjust.
 Identities = 194/413 (47%), Positives = 250/413 (61%), Gaps = 42/413 (10%)

Query  3    MDFAMLPPEVNSTRMYSGPGAGSLWAAAAAWDQVSAELQSAAETYRSVIASLTGWQWLGP  62
            MDFA+LPPEVNS RMY+GPGAGSLWAAA  WD ++AEL + AE Y SV++ L    W GP
Sbjct  1    MDFALLPPEVNSARMYTGPGAGSLWAAAGGWDSLAAELATTAEAYGSVLSGLAALHWRGP  60

Query  63   SSVRMGAAVTPYVEWLTTTAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVLSL  122
            ++  M      Y+ WL TTA + +QTA Q  AAA  FEQA+AMT+PPP + ANR Q+L+L
Sbjct  61   AAESMAVTAAAYIGWLYTTAEKTQQTAIQARAAALAFEQAYAMTLPPPLVAANRIQLLAL  120

Query  123  IATNFFGQNTAAIAALETQYAEMWEQDATAMYDYAATSAAARTLTPFTSPQQDTNSAGLP  182
            IATNFFGQNTAAIAA E QYAEMW QDA AMY YA  SAAA  LTPF+ P+Q TN AGL 
Sbjct  121  IATNFFGQNTAAIAATEAQYAEMWAQDAAAMYGYATASAAAALLTPFSPPRQTTNPAGLT  180

Query  183  AQSAEVSRATANAGAADGNWLGNLLEEIGILLLPIAPELTPFFLEAGEIVNAIPFPSIVG  242
            AQ+A VS+AT        + L  L+E +                   + + A+  PS + 
Sbjct  181  AQAAAVSQAT--------DPLSLLIETV------------------TQALQALTIPSFIP  214

Query  243  DEFCLLDGLLAWYATIGSINNINSMGTGIIGAEKNLGILPELGSAAAAAAPPPADIAPAF  302
            ++F  LD + A YAT+G   ++ S   G IGAE NLG+L  +G         PA++ P  
Sbjct  215  EDFTFLDAIFAGYATVGVTQDVESFVAGTIGAESNLGLL-NVGDEN------PAEVTPGD  267

Query  303  L---------APLTSMAKSLSDGALRGPGEVSAAMRGAGTIGQMSVPPAWKAPAVTTVRA  353
                      +P   ++ S + GA      V A++  A +IGQ+SVPP+W AP+   V A
Sbjct  268  FGIGELVSATSPGGGVSASGAGGAASVGNTVLASVGRANSIGQLSVPPSWAAPSTRPVSA  327

Query  354  FDATPMTTLPGGDAPAAGVPGLPGMPASGAGRAGVVPRYGVRLTVMTRPLSGG  406
                 +TTLPG D    G+PG+PG+P +    +GV+PRYGVRLTVM  P + G
Sbjct  328  LSPAGLTTLPGTDVAEHGMPGVPGVPVAAGRASGVLPRYGVRLTVMAHPPAAG  380


>gi|15842710|ref|NP_337747.1| PPE family protein [Mycobacterium tuberculosis CDC1551]
 gi|31794312|ref|NP_856805.1| PPE family protein [Mycobacterium bovis AF2122/97]
 gi|57117065|ref|YP_177935.1| PPE family protein [Mycobacterium tuberculosis H37Rv]
 69 more sequence titles
 Length=380

 Score =  298 bits (764),  Expect = 9e-79, Method: Compositional matrix adjust.
 Identities = 194/413 (47%), Positives = 250/413 (61%), Gaps = 42/413 (10%)

Query  3    MDFAMLPPEVNSTRMYSGPGAGSLWAAAAAWDQVSAELQSAAETYRSVIASLTGWQWLGP  62
            MDFA+LPPEVNS RMY+GPGAGSL AAA  WD ++AEL + AE Y SV++ L    W GP
Sbjct  1    MDFALLPPEVNSARMYTGPGAGSLLAAAGGWDSLAAELATTAEAYGSVLSGLAALHWRGP  60

Query  63   SSVRMGAAVTPYVEWLTTTAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVLSL  122
            ++  M     PY+ WL TTA + +QTA Q  AAA  FEQA+AMT+PPP + ANR Q+L+L
Sbjct  61   AAESMAVTAAPYIGWLYTTAEKTQQTAIQARAAALAFEQAYAMTLPPPVVAANRIQLLAL  120

Query  123  IATNFFGQNTAAIAALETQYAEMWEQDATAMYDYAATSAAARTLTPFTSPQQDTNSAGLP  182
            IATNFFGQNTAAIAA E QYAEMW QDA AMY YA  SAAA  LTPF+ P+Q TN AGL 
Sbjct  121  IATNFFGQNTAAIAATEAQYAEMWAQDAAAMYGYATASAAAALLTPFSPPRQTTNPAGLT  180

Query  183  AQSAEVSRATANAGAADGNWLGNLLEEIGILLLPIAPELTPFFLEAGEIVNAIPFPSIVG  242
            AQ+A VS+AT        + L  L+E +                   + + A+  PS + 
Sbjct  181  AQAAAVSQAT--------DPLSLLIETV------------------TQALQALTIPSFIP  214

Query  243  DEFCLLDGLLAWYATIGSINNINSMGTGIIGAEKNLGILPELGSAAAAAAPPPADIAPAF  302
            ++F  LD + A YAT+G   ++ S   G IGAE NLG+L  +G         PA++ P  
Sbjct  215  EDFTFLDAIFAGYATVGVTQDVESFVAGTIGAESNLGLL-NVGDEN------PAEVTPGD  267

Query  303  L---------APLTSMAKSLSDGALRGPGEVSAAMRGAGTIGQMSVPPAWKAPAVTTVRA  353
                      +P   ++ S + GA      V A++  A +IGQ+SVPP+W AP+   V A
Sbjct  268  FGIGELVSATSPGGGVSASGAGGAASVGNTVLASVGRANSIGQLSVPPSWAAPSTRPVSA  327

Query  354  FDATPMTTLPGGDAPAAGVPGLPGMPASGAGRAGVVPRYGVRLTVMTRPLSGG  406
                 +TTLPG D    G+PG+PG+P +    +GV+PRYGVRLTVM  P + G
Sbjct  328  LSPAGLTTLPGTDVAEHGMPGVPGVPVAAGRASGVLPRYGVRLTVMAHPPAAG  380


>gi|306782177|ref|ZP_07420514.1| PPE family protein [Mycobacterium tuberculosis SUMu002]
 gi|306790362|ref|ZP_07428684.1| PPE family protein [Mycobacterium tuberculosis SUMu004]
 gi|306794889|ref|ZP_07433191.1| PPE family protein [Mycobacterium tuberculosis SUMu005]
 gi|308325139|gb|EFP13990.1| PPE family protein [Mycobacterium tuberculosis SUMu002]
 gi|308333218|gb|EFP22069.1| PPE family protein [Mycobacterium tuberculosis SUMu004]
 gi|308336675|gb|EFP25526.1| PPE family protein [Mycobacterium tuberculosis SUMu005]
Length=380

 Score =  298 bits (763),  Expect = 1e-78, Method: Compositional matrix adjust.
 Identities = 195/413 (48%), Positives = 250/413 (61%), Gaps = 42/413 (10%)

Query  3    MDFAMLPPEVNSTRMYSGPGAGSLWAAAAAWDQVSAELQSAAETYRSVIASLTGWQWLGP  62
            MDFA+LPPEVNS RMY+GPGAGSL AAA  WD ++AEL + AE Y SV++ L    W GP
Sbjct  1    MDFALLPPEVNSARMYTGPGAGSLLAAAGGWDSLAAELATTAEAYGSVLSGLAALHWRGP  60

Query  63   SSVRMGAAVTPYVEWLTTTAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVLSL  122
            ++  M     PY+ WL TTA + +QTA Q  AAA  FEQA+AMT+PPP + ANR Q+L+L
Sbjct  61   AAESMAVTAAPYIGWLYTTAEKTQQTAIQARAAALAFEQAYAMTLPPPVVAANRIQLLAL  120

Query  123  IATNFFGQNTAAIAALETQYAEMWEQDATAMYDYAATSAAARTLTPFTSPQQDTNSAGLP  182
            IATNFFGQNTAAIAA E QYAEMW QDA AMY YA  SAAA  LTPF+ P+Q TN AGL 
Sbjct  121  IATNFFGQNTAAIAATEAQYAEMWAQDAAAMYGYATASAAAALLTPFSPPRQTTNPAGLT  180

Query  183  AQSAEVSRATANAGAADGNWLGNLLEEIGILLLPIAPELTPFFLEAGEIVNAIPFPSIVG  242
            AQ+A VS+AT        + L  L+E                   A + + A+  PS + 
Sbjct  181  AQAAAVSQAT--------DPLSLLIE------------------TATQALQALTIPSFIP  214

Query  243  DEFCLLDGLLAWYATIGSINNINSMGTGIIGAEKNLGILPELGSAAAAAAPPPADIAPAF  302
            ++F  LD + A YAT+G   ++ S   G IGAE NLG+L  +G         PA++ P  
Sbjct  215  EDFTFLDAIFAGYATVGVTQDVESFVAGTIGAESNLGLL-NVGDEN------PAEVTPGD  267

Query  303  L---------APLTSMAKSLSDGALRGPGEVSAAMRGAGTIGQMSVPPAWKAPAVTTVRA  353
                      +P   ++ S + GA      V A++  A +IGQ+SVPP+W AP+   V A
Sbjct  268  FGIGELVSATSPGGGVSASGAGGAASVGNTVLASVGRANSIGQLSVPPSWAAPSTRPVSA  327

Query  354  FDATPMTTLPGGDAPAAGVPGLPGMPASGAGRAGVVPRYGVRLTVMTRPLSGG  406
                 +TTLPG D    G+PG+PG+P +    +GV+PRYGVRLTVM  P + G
Sbjct  328  LSPAGLTTLPGTDVAEHGMPGVPGVPVAAGRASGVLPRYGVRLTVMAHPPAAG  380


>gi|183981529|ref|YP_001849820.1| PPE family protein, PPE51_1 [Mycobacterium marinum M]
 gi|183174855|gb|ACC39965.1| PPE family protein, PPE51_1 [Mycobacterium marinum M]
Length=381

 Score =  292 bits (748),  Expect = 6e-77, Method: Compositional matrix adjust.
 Identities = 203/406 (50%), Positives = 262/406 (65%), Gaps = 27/406 (6%)

Query  3    MDFAMLPPEVNSTRMYSGPGAGSLWAAAAAWDQVSAELQSAAETYRSVIASLTGWQWLGP  62
            M++A LPPEVNS RMYSGPG+ SL AAAA+WD V+ EL SAAE YRSVI++L+G  W GP
Sbjct  1    MNYAFLPPEVNSARMYSGPGSASLLAAAASWDMVAIELASAAEGYRSVISTLSGMYWWGP  60

Query  63   SSVRMGAAVTPYVEWLTTTAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVLSL  122
            +S  M AA  P+++WL  T A A +TA Q  AAA  +EQA+AMTVPP  + ANRA +++L
Sbjct  61   ASAAMLAATGPFIDWLEITGALASETANQAAAAAAAYEQAYAMTVPPIVVAANRALLVAL  120

Query  123  IATNFFGQNTAAIAALETQYAEMWEQDATAMYDYAATSAAARTLTPFTSPQQDTNSAGLP  182
            +A+NFFGQNTAAI A E +YAEMW QDA AMYDYAATSA A  L PF++P QDTN AGL 
Sbjct  121  VASNFFGQNTAAIEATEAEYAEMWAQDAGAMYDYAATSAMATALVPFSAPGQDTNPAGLA  180

Query  183  AQSAEVSRATANAGAADGNWLGNLLEEIGILLLPIAPELTPFFLEAGEIVNAIPFPSIVG  242
            AQSA VS+A  NA A+         + +   L  + P+  P             +P+I+ 
Sbjct  181  AQSAAVSQAAGNAPAS--------AQSVWSQLTSLVPDALPSLSN---------WPNILP  223

Query  243  DEFCLLDGLLAWYATIGSINNINSMGTGIIGAEKNLGILPELGSAAAAAAPPPADIAPAF  302
            D+F +LDG+ A YAT+G   ++ S   GIIGAE NLG+L        AA+  PA++ P  
Sbjct  224  DDFSILDGIFAMYATVGVTQDVESFCAGIIGAENNLGLL-------GAASENPAEVTPGA  276

Query  303  LAPLTSMAKSLSDGALRG-PGEVSAAMRGAGTIGQMSVPPAWKAPAVTTVRAFDATPMTT  361
            L  L +M  S    A+ G    V+ +M  AG+IGQ+SVPP+W AP+  +  A   + +TT
Sbjct  277  LG-LGAMFSSAERSAVGGATNAVTVSMSRAGSIGQLSVPPSWAAPSSGSASALSVSGLTT  335

Query  362  LPGGDAPAAGVPGLPGMPASGAGRA-GVVPRYGVRLTVMTRPLSGG  406
            +PG +    G PG+PGMP     RA  V+PRYGVRLTVM RP + G
Sbjct  336  IPGTEVAEQGAPGMPGMPVGTGKRATSVIPRYGVRLTVMARPPAAG  381


>gi|240168614|ref|ZP_04747273.1| PPE family protein, PPE51_2 [Mycobacterium kansasii ATCC 12478]
Length=378

 Score =  285 bits (729),  Expect = 1e-74, Method: Compositional matrix adjust.
 Identities = 201/405 (50%), Positives = 256/405 (64%), Gaps = 28/405 (6%)

Query  3    MDFAMLPPEVNSTRMYSGPGAGSLWAAAAAWDQVSAELQSAAETYRSVIASLTGWQWLGP  62
            MDFA+LPPEVNS R+Y+GPG GSL AAA +WD ++ EL + A+TY SV++ LT   W GP
Sbjct  1    MDFALLPPEVNSGRIYTGPGPGSLLAAAGSWDALATELDTTAQTYESVVSGLTTLDWYGP  60

Query  63   SSVRMGAAVTPYVEWLTTTAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVLSL  122
            +S  M A V PYV WL TTA Q +QTA Q  AAA  F+QAFAMTVPPPAI ANR Q+++L
Sbjct  61   ASESMAAKVAPYVSWLYTTATQTKQTAMQARAAAAAFDQAFAMTVPPPAIAANRIQLMAL  120

Query  123  IATNFFGQNTAAIAALETQYAEMWEQDATAMYDYAATSAAARTLTPFTSPQQDTNSAGLP  182
            IATNFFGQNTAAIAA E QYAEMW QDA AMY YA +S AA  L PF SP Q T+ AGL 
Sbjct  121  IATNFFGQNTAAIAATEAQYAEMWAQDAAAMYGYATSSTAAAQLMPFPSPSQTTDPAGLS  180

Query  183  AQSAEVSRATANAGAADGNWLGNLLEEIGILLLPIAPELTPFFLEAGEIVNAIPFPSIVG  242
            AQSA V++A A+A A D                PI+ +L     ++   ++ +  P+ + 
Sbjct  181  AQSAAVAQANASAAATD----------------PIS-QLVAAVSQSLGALSGLQIPNFLP  223

Query  243  DEFCLLDGLLAWYATIGSINNINSMGTGIIGAEKNLGILPELGSAAAAAAPPPADIAPAF  302
             ++ +LDG+ A YAT  +I+++ S+  GIIG E  L  +P L SA  A         PA 
Sbjct  224  ADYAVLDGIFAIYATFSAIDSVESIADGIIGDEAAL--VPALTSATEA--------MPAE  273

Query  303  LAPLTSMAKSLSDGALRGPGEVSAAMRGAGTIGQMSVPPAWKAPAVTTVRAFDATPMTTL  362
             + L +  + +  G+  GP  V A+   AG+IGQ+SVP +W APA  TV A     +TT+
Sbjct  274  ASTLVAAQQPVGAGSGLGPNAVLASAGRAGSIGQLSVPASWAAPATRTVSALSPAGLTTI  333

Query  363  PGGDAPAAGVPGLPGMPASGAGRA-GVVPRYGVRLTVMTRPLSGG  406
            PG +   AG PG+PGM      RA GV+PRYGVRLTVM  P + G
Sbjct  334  PGTEEAGAGAPGVPGMAVPAQSRASGVLPRYGVRLTVMAHPPAAG  378


>gi|118618187|ref|YP_906519.1| PPE family protein [Mycobacterium ulcerans Agy99]
 gi|118570297|gb|ABL05048.1| PPE family protein [Mycobacterium ulcerans Agy99]
Length=381

 Score =  282 bits (721),  Expect = 8e-74, Method: Compositional matrix adjust.
 Identities = 200/406 (50%), Positives = 258/406 (64%), Gaps = 27/406 (6%)

Query  3    MDFAMLPPEVNSTRMYSGPGAGSLWAAAAAWDQVSAELQSAAETYRSVIASLTGWQWLGP  62
            M++A LPPEVNS RMYSGPG+ SL AAAA+WD V+ EL SAAE YRSVI++L+G  W GP
Sbjct  1    MNYAFLPPEVNSARMYSGPGSASLLAAAASWDMVAIELASAAEGYRSVISTLSGMYWWGP  60

Query  63   SSVRMGAAVTPYVEWLTTTAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVLSL  122
            +S  M AA  P++ WL  T A A +TA Q  AAA  +EQA+AMTVPP  + ANRA +++L
Sbjct  61   ASAAMLAATGPFIGWLEITGALASETANQAAAAAAAYEQAYAMTVPPIVVAANRALLVAL  120

Query  123  IATNFFGQNTAAIAALETQYAEMWEQDATAMYDYAATSAAARTLTPFTSPQQDTNSAGLP  182
            +A+N FGQNTAAI A E +YAEMW QDA AMYDYAATSA A  L PF++P QDTN AGL 
Sbjct  121  VASNIFGQNTAAIEATEAEYAEMWAQDAGAMYDYAATSAMATALVPFSAPGQDTNPAGLA  180

Query  183  AQSAEVSRATANAGAADGNWLGNLLEEIGILLLPIAPELTPFFLEAGEIVNAIPFPSIVG  242
            AQSA VS+A  NA A+         + +   L  + P+  P             +P+I+ 
Sbjct  181  AQSAAVSQAAGNAPASA--------QSVWSQLTSLVPDALPSLSN---------WPNILP  223

Query  243  DEFCLLDGLLAWYATIGSINNINSMGTGIIGAEKNLGILPELGSAAAAAAPPPADIAPAF  302
            D+F +LDG+ A YAT+G   ++ S   GIIGA  NLG+L        AA+   A++ P  
Sbjct  224  DDFSMLDGIFAMYATVGVTQDVESFCAGIIGAGNNLGLL-------GAASENSAEVTPGA  276

Query  303  LAPLTSMAKSLSDGALRG-PGEVSAAMRGAGTIGQMSVPPAWKAPAVTTVRAFDATPMTT  361
            L  L +M  S    A+ G    V+ +M  AG+IGQ+SVPP+W AP+  +  A   + +TT
Sbjct  277  LG-LGAMFSSAERSAVGGATNAVTVSMSRAGSIGQLSVPPSWAAPSSGSASALSVSGLTT  335

Query  362  LPGGDAPAAGVPGLPGMPASGAGRA-GVVPRYGVRLTVMTRPLSGG  406
            +PG +    G PG+PGMP     RA  V+PRYGVRLTVM RP + G
Sbjct  336  IPGTEVAEQGAPGMPGMPVGTGKRATSVIPRYGVRLTVMARPPAAG  381


>gi|167970194|ref|ZP_02552471.1| PPE family protein [Mycobacterium tuberculosis H37Ra]
Length=480

 Score =  281 bits (719),  Expect = 1e-73, Method: Compositional matrix adjust.
 Identities = 185/399 (47%), Positives = 240/399 (61%), Gaps = 42/399 (10%)

Query  3    MDFAMLPPEVNSTRMYSGPGAGSLWAAAAAWDQVSAELQSAAETYRSVIASLTGWQWLGP  62
            MDFA+LPPEVNS RMY+GPGAGSL AAA  WD ++AEL + AE Y SV++ L    W GP
Sbjct  1    MDFALLPPEVNSARMYTGPGAGSLLAAAGGWDSLAAELATTAEAYGSVLSGLAALHWRGP  60

Query  63   SSVRMGAAVTPYVEWLTTTAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVLSL  122
            ++  M     PY+ WL TTA + +QTA Q  AAA  FEQA+AMT+PPP + ANR Q+L+L
Sbjct  61   AAESMAVTAAPYIGWLYTTAEKTQQTAIQARAAALAFEQAYAMTLPPPVVAANRIQLLAL  120

Query  123  IATNFFGQNTAAIAALETQYAEMWEQDATAMYDYAATSAAARTLTPFTSPQQDTNSAGLP  182
            IATNFFGQNTAAIAA E QYAEMW QDA AMY YA  SAAA  LTPF+ P+Q TN AGL 
Sbjct  121  IATNFFGQNTAAIAATEAQYAEMWAQDAAAMYGYATASAAAALLTPFSPPRQTTNPAGLT  180

Query  183  AQSAEVSRATANAGAADGNWLGNLLEEIGILLLPIAPELTPFFLEAGEIVNAIPFPSIVG  242
            AQ+A VS+AT        + L  L+E +                   + + A+  PS + 
Sbjct  181  AQAAAVSQAT--------DPLSLLIETV------------------TQALQALTIPSFIP  214

Query  243  DEFCLLDGLLAWYATIGSINNINSMGTGIIGAEKNLGILPELGSAAAAAAPPPADIAPAF  302
            ++F  LD + A YAT+G   ++ S   G IGAE NLG+L  +G         PA++ P  
Sbjct  215  EDFTFLDAIFAGYATVGVTQDVESFVAGTIGAESNLGLL-NVGDEN------PAEVTPGD  267

Query  303  L---------APLTSMAKSLSDGALRGPGEVSAAMRGAGTIGQMSVPPAWKAPAVTTVRA  353
                      +P   ++ S + GA      V A++  A +IGQ+SVPP+W AP+   V A
Sbjct  268  FGIGELVSATSPGGGVSASGAGGAASVGNTVLASVGRANSIGQLSVPPSWAAPSTRPVSA  327

Query  354  FDATPMTTLPGGDAPAAGVPGLPGMPASGAGRAGVVPRY  392
                 +TTLPG D    G+PG+PG+P +    +GV+PRY
Sbjct  328  LSPAGLTTLPGTDVAEHGMPGVPGVPVAAGRASGVLPRY  366


>gi|118617918|ref|YP_906250.1| PPE family protein [Mycobacterium ulcerans Agy99]
 gi|118570028|gb|ABL04779.1| PPE family protein [Mycobacterium ulcerans Agy99]
Length=381

 Score =  279 bits (713),  Expect = 6e-73, Method: Compositional matrix adjust.
 Identities = 199/406 (50%), Positives = 257/406 (64%), Gaps = 27/406 (6%)

Query  3    MDFAMLPPEVNSTRMYSGPGAGSLWAAAAAWDQVSAELQSAAETYRSVIASLTGWQWLGP  62
            M++A LPPEVNS RMYSGPG+ SL AAAA+WD V+ EL SAAE YRSVI++L+G  W GP
Sbjct  1    MNYAFLPPEVNSARMYSGPGSASLLAAAASWDMVAIELASAAEGYRSVISTLSGMYWWGP  60

Query  63   SSVRMGAAVTPYVEWLTTTAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVLSL  122
            +S  M AA  P++ WL  T A A +TA Q  AAA  +EQA+AMTVPP  + ANRA +++L
Sbjct  61   ASAAMLAATGPFIGWLEITGALASETANQAAAAAAAYEQAYAMTVPPIVVAANRALLVAL  120

Query  123  IATNFFGQNTAAIAALETQYAEMWEQDATAMYDYAATSAAARTLTPFTSPQQDTNSAGLP  182
            +A+N FGQNTAAI A E +YAEMW QDA AMYDYAATSA A  L PF++P QDTN AGL 
Sbjct  121  VASNIFGQNTAAIEATEAEYAEMWAQDAGAMYDYAATSAMATALVPFSAPGQDTNPAGLA  180

Query  183  AQSAEVSRATANAGAADGNWLGNLLEEIGILLLPIAPELTPFFLEAGEIVNAIPFPSIVG  242
            AQSA VS+A  NA A+         + +   L  + P+  P             +P+I+ 
Sbjct  181  AQSAAVSQAAGNAPASA--------QSVWSQLTSLVPDALPSLSN---------WPNILP  223

Query  243  DEFCLLDGLLAWYATIGSINNINSMGTGIIGAEKNLGILPELGSAAAAAAPPPADIAPAF  302
            D+F +LDG+ A YAT+G   ++ S   GIIGA  NLG+L        AA+   A++ P  
Sbjct  224  DDFSMLDGIFAMYATVGVTQDVESFCAGIIGAGNNLGLL-------GAASENSAEVTPGA  276

Query  303  LAPLTSMAKSLSDGALRG-PGEVSAAMRGAGTIGQMSVPPAWKAPAVTTVRAFDATPMTT  361
            L  L +M  S    A+ G    V+ +M  AG+IGQ+SVPP+W AP+  +  A   + +TT
Sbjct  277  LG-LGAMFSSAERSAVGGATNAVTVSMSRAGSIGQLSVPPSWAAPSSGSASALSVSGLTT  335

Query  362  LPGGDAPAAGVPGLPGMPASGAGRA-GVVPRYGVRLTVMTRPLSGG  406
            +PG +    G PG+PGMP     RA  V+ RYGVRLTVM RP + G
Sbjct  336  IPGTEVAEQGAPGMPGMPVGTGKRATSVILRYGVRLTVMARPPAAG  381


>gi|323717804|gb|EGB27001.1| hypothetical protein TMMG_00020 [Mycobacterium tuberculosis CDC1551A]
Length=140

 Score =  276 bits (706),  Expect = 4e-72, Method: Compositional matrix adjust.
 Identities = 140/140 (100%), Positives = 140/140 (100%), Gaps = 0/140 (0%)

Query  1    MFMDFAMLPPEVNSTRMYSGPGAGSLWAAAAAWDQVSAELQSAAETYRSVIASLTGWQWL  60
            MFMDFAMLPPEVNSTRMYSGPGAGSLWAAAAAWDQVSAELQSAAETYRSVIASLTGWQWL
Sbjct  1    MFMDFAMLPPEVNSTRMYSGPGAGSLWAAAAAWDQVSAELQSAAETYRSVIASLTGWQWL  60

Query  61   GPSSVRMGAAVTPYVEWLTTTAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVL  120
            GPSSVRMGAAVTPYVEWLTTTAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVL
Sbjct  61   GPSSVRMGAAVTPYVEWLTTTAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVL  120

Query  121  SLIATNFFGQNTAAIAALET  140
            SLIATNFFGQNTAAIAALET
Sbjct  121  SLIATNFFGQNTAAIAALET  140


>gi|183983449|ref|YP_001851740.1| PPE family protein, PPE51_3 [Mycobacterium marinum M]
 gi|183176775|gb|ACC41885.1| PPE family protein, PPE51_3 [Mycobacterium marinum M]
Length=380

 Score =  268 bits (685),  Expect = 1e-69, Method: Compositional matrix adjust.
 Identities = 201/406 (50%), Positives = 257/406 (64%), Gaps = 28/406 (6%)

Query  3    MDFAMLPPEVNSTRMYSGPGAGSLWAAAAAWDQVSAELQSAAETYRSVIASLTGWQWLGP  62
            M++A LPPEVNS RMYSGPG  SL AAAA+WD V+ EL S AE YRSVI++L+G  W GP
Sbjct  1    MNYAFLPPEVNSARMYSGPGPESLLAAAASWDMVAIELASTAEGYRSVISTLSGMYWWGP  60

Query  63   SSVRMGAAVTPYVEWLTTTAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVLSL  122
            +S  M AA  P+++WL  T A A +TA Q TAAA  +EQA+AMTVPP  + ANRA + +L
Sbjct  61   ASAAMLAATGPFIDWLEITGALASETANQATAAAAAYEQAYAMTVPPIVVAANRALLAAL  120

Query  123  IATNFFGQNTAAIAALETQYAEMWEQDATAMYDYAATSAAARTLTPFTSPQQDTNSAGLP  182
            IA+N FGQNTAAI A E +YAEMW QDA AMYDYAATSA A  L PF  PQQ TN AGLP
Sbjct  121  IASNIFGQNTAAIEATEAEYAEMWAQDAGAMYDYAATSAMATALEPFPGPQQHTNPAGLP  180

Query  183  AQSAEVSRATANAGAADGNWLGNLLEEIGILLLPIAPELTPFFLEAGEIVNAIPFPSIVG  242
            AQ A VS+A A++     + L  L     I L+P          +A +++   P   I+ 
Sbjct  181  AQGAAVSKAAASSEEGSQSLLSQL-----IALVP----------QALQVLGIWP---ILP  222

Query  243  DEFCLLDGLLAWYATIGSINNINSMGTGIIGAEKNLGILPELGSAAAAAAPPPADIAPAF  302
            +EF LLD + A YAT+G   +  ++   II A+ NLG+L        AA+  PA++AP  
Sbjct  223  EEFTLLDAIFAMYATVGMTADAVTIPVAIIAADNNLGLL-------GAASENPAELAPGA  275

Query  303  LAPLTSMAKSLSDGALRGPGE-VSAAMRGAGTIGQMSVPPAWKAPAVTTVRAFDATPMTT  361
            L  + +   S   GA RG    V+ +M  AG+IGQ+SVPP+W AP+  +  A   + +TT
Sbjct  276  LG-VGAKLSSAEMGAARGAANAVTVSMSRAGSIGQLSVPPSWAAPSSGSASALSVSGLTT  334

Query  362  LPGGDAPAAGVPGLPGMPASGAGRA-GVVPRYGVRLTVMTRPLSGG  406
            +PG +    G PG+PGMP     RA  V+PRYGVRLTVM RP + G
Sbjct  335  IPGTEVAEQGAPGVPGMPVGTGKRATSVIPRYGVRLTVMARPPAAG  380


>gi|289448814|ref|ZP_06438558.1| PPE family protein [Mycobacterium tuberculosis CPHL_A]
 gi|289421772|gb|EFD18973.1| PPE family protein [Mycobacterium tuberculosis CPHL_A]
Length=387

 Score =  260 bits (665),  Expect = 3e-67, Method: Compositional matrix adjust.
 Identities = 190/369 (52%), Positives = 232/369 (63%), Gaps = 38/369 (10%)

Query  3    MDFAMLPPEVNSTRMYSGPGAGSLWAAAAAWDQVSAELQSAAETYRSVIASLTGWQWLGP  62
            MD+A LPPE+NS RMYSGPG  S+  AAA+WD ++AEL SAAE Y SVIA LTG  W GP
Sbjct  1    MDYAFLPPEINSARMYSGPGPNSMLVAAASWDALAAELASAAENYGSVIARLTGMHWWGP  60

Query  63   SSVRMGAAVTPYVEWLTTTAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVLSL  122
            +S  M A   PYVEWL  TAAQ +QTATQ  AAA  FEQA AMTVPP  + ANRA++ +L
Sbjct  61   ASTSMLAMSAPYVEWLERTAAQTKQTATQARAAAAAFEQAHAMTVPPALVTANRAELKAL  120

Query  123  IATNFFGQNTAAIAALETQYAEMWEQDATAMYDYAATSAAARTLTPFTSPQQDTNSAGLP  182
            IA+N  GQNTAAIAA+E QYAEMW QDA AMY YA TSAAAR LTPF+SPQQ TN AGL 
Sbjct  121  IASNLLGQNTAAIAAIEAQYAEMWAQDAAAMYGYATTSAAARQLTPFSSPQQTTNPAGLA  180

Query  183  AQSAEVSRATANAGAADGNWLGNLLEEIGILLLPIAPELTPFFLEAGEIVNAIPFPSIVG  242
            AQ+A V++A  N+        GN    +         +L+ F  +A E      +P+I+ 
Sbjct  181  AQNAAVTQAATNSA-------GNTPTALS--------QLSSFLSQAVEAPTG--WPNILP  223

Query  243  DEFCLLDGLLAWYATIGSINNINSMGTGIIGAEKNLGILPELGSAAAAAAPPPADIAPAF  302
            D+F +LDG+ A YAT+G   +I S+  GIIGAE NLG+L        AA+  PA++AP  
Sbjct  224  DDFTILDGIFAAYATVGVTQDIESICAGIIGAENNLGLL-------GAASENPAELAPGA  276

Query  303  L---APLTSMAK----SLSDGALRGPGEVSAAMRGAGTIGQMSVPPAWKAPAVTTVRAFD  355
                A L+S  K    S+ D  L   G        AG+IG MSVPP+W  P+ T V A  
Sbjct  277  FGIDAALSSAEKGAAASMHDAVLASAGR-------AGSIGPMSVPPSWATPSSTPVSALS  329

Query  356  ATPMTTLPG  364
               +TTL G
Sbjct  330  GAGLTTLDG  338


>gi|289575846|ref|ZP_06456073.1| PPE family protein [Mycobacterium tuberculosis K85]
 gi|339633142|ref|YP_004724784.1| PPE family protein [Mycobacterium africanum GM041182]
 gi|289540277|gb|EFD44855.1| PPE family protein [Mycobacterium tuberculosis K85]
 gi|339332498|emb|CCC28213.1| PPE family protein [Mycobacterium africanum GM041182]
Length=345

 Score =  250 bits (639),  Expect = 3e-64, Method: Compositional matrix adjust.
 Identities = 182/348 (53%), Positives = 222/348 (64%), Gaps = 38/348 (10%)

Query  3    MDFAMLPPEVNSTRMYSGPGAGSLWAAAAAWDQVSAELQSAAETYRSVIASLTGWQWLGP  62
            MD+A LPPE+NS RMYSGPG  S+  AAA+WD ++AEL SAAE Y SVIA LTG  W GP
Sbjct  1    MDYAFLPPEINSARMYSGPGPNSMLVAAASWDALAAELASAAENYGSVIARLTGMHWWGP  60

Query  63   SSVRMGAAVTPYVEWLTTTAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVLSL  122
            +S  M A   PYVEWL  TAAQ +QTATQ  AAA  FEQA AMTVPP  + ANRA++ +L
Sbjct  61   ASTSMLAMSAPYVEWLERTAAQTKQTATQARAAAAAFEQAHAMTVPPALVTANRAELKAL  120

Query  123  IATNFFGQNTAAIAALETQYAEMWEQDATAMYDYAATSAAARTLTPFTSPQQDTNSAGLP  182
            IA+N  GQNTAAIAA+E QYAEMW QDA AMY YA TSAAAR LTPF+SPQQ TN AGL 
Sbjct  121  IASNLLGQNTAAIAAIEAQYAEMWAQDAAAMYGYATTSAAARQLTPFSSPQQTTNPAGLA  180

Query  183  AQSAEVSRATANAGAADGNWLGNLLEEIGILLLPIAPELTPFFLEAGEIVNAIPFPSIVG  242
            AQ+A V++A  N+        GN    +         +L+ F  +A E      +P+I+ 
Sbjct  181  AQNAAVTQAATNSA-------GNTPTALS--------QLSSFLSQAVEAPTG--WPNILP  223

Query  243  DEFCLLDGLLAWYATIGSINNINSMGTGIIGAEKNLGILPELGSAAAAAAPPPADIAPAF  302
            D+F +LDG+ A YAT+G   +I S+  GIIGAE NLG+L        AA+  PA++AP  
Sbjct  224  DDFTILDGIFAAYATVGVTQDIESICAGIIGAENNLGLL-------GAASENPAELAPGA  276

Query  303  L---APLTSMAK----SLSDGALRGPGEVSAAMRGAGTIGQMSVPPAW  343
                A L+S  K    S+ D  L   G        AG+IG MSVPP+W
Sbjct  277  FGIDAALSSAEKGAAASMHDAVLASAGR-------AGSIGPMSVPPSW  317


>gi|240172861|ref|ZP_04751520.1| PPE family protein, PPE31 [Mycobacterium kansasii ATCC 12478]
Length=401

 Score =  227 bits (579),  Expect = 2e-57, Method: Compositional matrix adjust.
 Identities = 185/421 (44%), Positives = 237/421 (57%), Gaps = 41/421 (9%)

Query  3    MDFAMLPPEVNSTRMYSGPGAGSLWAAAAAWDQVSAELQSAAETYRSVIASLTGWQWLGP  62
            +DFAMLPPE+NS RMYSGPG+G + AAA+AW  ++AEL++ A +Y SV+A+LTG +W GP
Sbjct  5    LDFAMLPPEINSARMYSGPGSGPMLAAASAWKSLAAELRATALSYHSVLAALTGEEWYGP  64

Query  63   SSVRMGAAVTPYVEWLTTTAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVLSL  122
            +S  M AA  PYV WL TTA QA QTA Q  AAA  +E AF  TVPPP I ANRAQ+++L
Sbjct  65   ASASMAAAAAPYVAWLNTTAVQAEQTAVQAEAAAGAYEAAFGATVPPPVIAANRAQLMAL  124

Query  123  IATNFFGQNTAAIAALETQYAEMWEQDATAMYDYAATSAAARTLTPFTSPQQDTNSAGLP  182
            IATN  GQNT AIAA E QY EMW QDA AMY YA +SAAA  L+PF  PQQ TN +GL 
Sbjct  125  IATNILGQNTPAIAATEAQYTEMWAQDAMAMYGYAGSSAAATQLSPFVEPQQATNPSGLA  184

Query  183  AQSAEVSRATANAGAADGNWLGNLLEEIGILLLPIAPELTPFFLEAGEIVNAIPFPSIVG  242
            AQ+A V+ A+AN+     + L  L+             + P  L+     N+  +  ++ 
Sbjct  185  AQAAAVTEASANSAGNQSSTLSGLI------------SMVPSALQGLSGPNSTSWLQVIW  232

Query  243  DEFCLLDGL-LAWYATIGSI--------NNINSMGTGIIG---AEKNLGILPELGSAAAA  290
            D   LL G   AW+ T+ ++        N I S G  + G   A     +L    +A AA
Sbjct  233  D---LLTGSGPAWWQTLWNVWGPNANVWNTITSTGLFVPGSTFAPFMASVLAGAVAADAA  289

Query  291  AAPPPADIAPAFLAPLTSMAKSLSDGALRGPGEVSAAMRGAGTIGQMSVPPAWKAPAVTT  350
                 A            +A + S G+      VSA +  AG +G++SVPPAW A A   
Sbjct  290  QDASAAAAGVGSGLAAGPLASTGSVGS-----AVSAGLGNAGIVGKLSVPPAWTAAAPLH  344

Query  351  V---RAFDATPMTTLPGGDAPAAGVPGLP--GMPASGAGRAGVVPRYGVRLTVMTRPLSG  405
                 A   TPM   P   A AAG+PG+P   M     GRA  VP+YG R T + RP + 
Sbjct  345  SPLGSALGGTPMVAPP--PAVAAGMPGMPFGNMAGQPFGRA--VPQYGFRPTFVARPPAA  400

Query  406  G  406
            G
Sbjct  401  G  401


>gi|41409283|ref|NP_962119.1| hypothetical protein MAP3185 [Mycobacterium avium subsp. paratuberculosis 
K-10]
 gi|41398103|gb|AAS05733.1| hypothetical protein MAP_3185 [Mycobacterium avium subsp. paratuberculosis 
K-10]
 gi|336459363|gb|EGO38306.1| PPE family protein [Mycobacterium avium subsp. paratuberculosis 
S397]
Length=362

 Score =  224 bits (571),  Expect = 2e-56, Method: Compositional matrix adjust.
 Identities = 184/406 (46%), Positives = 226/406 (56%), Gaps = 46/406 (11%)

Query  3    MDFAMLPPEVNSTRMYSGPGAGSLWAAAAAWDQVSAELQSAAETYRSVIASLTGWQWLGP  62
            MDF  LPPEVNS RMY+GPG+GSL AAA +WD ++AEL   A  Y SV+A LTG  W GP
Sbjct  1    MDFGFLPPEVNSARMYAGPGSGSLLAAAGSWDSLAAELSITAAVYESVLAGLTGLYWHGP  60

Query  63   SSVRMGAAVTPYVEWLTTTAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVLSL  122
            +S  M A   PYV WL TTA +A+QTATQ  AAA  +E A AMTVPP A+ ANR Q+ +L
Sbjct  61   ASRAMAAGAAPYVGWLHTTAERAQQTATQARAAAAAYELAHAMTVPPAAVAANRTQLAAL  120

Query  123  IATNFFGQNTAAIAALETQYAEMWEQDATAMYDYAATSAAARTLTPFTSPQQDTNSAGLP  182
            +ATNFFGQNTAAIAA E QYAE W QDA AMY Y+A+SAAA   +PF SP++ T+  G+ 
Sbjct  121  VATNFFGQNTAAIAATEAQYAEYWAQDAAAMYAYSASSAAAAQFSPFPSPRRTTDPGGV-  179

Query  183  AQSAEVSRATANAGAADGNWLGNLLEEIGILLLPIAPELTPFFLEAGEIVNAIPFPSIVG  242
                     TA   A      G+   + G  ++P           AG   + IP      
Sbjct  180  ---------TAQQAAVAAAETGSTGTDSGAQVIPP---------TAG--ASEIPL-----  214

Query  243  DEFCLLDGLLAWYATIGSINNINSMGTGIIGAEKNLGILPELGSAAAAAAPPPADIAPAF  302
             +F +LD +L    T  SI     +  GII A+KNLGILP L +             PA 
Sbjct  215  -DFRILDTILGAQTTFRSIFTTEGIPAGIIQADKNLGILPNLAT------------VPAA  261

Query  303  LAPLTSMAKSLSDGALRGPGEVSAAMRGAGTIGQMSVPPAWKAPAVTTVRAFDATPMTTL  362
            L    +++ S S     G G + A +  A  IG MSVP  W A     V A   T  +  
Sbjct  262  LPRTPALSASPS-----GLGRIDAVLARAARIGPMSVPAGWTAATGNPVAAAPVTGWSEP  316

Query  363  PGGDA-PAAGVPGLPGMPASGAGRAG-VVPRYGVRLTVMTRPLSGG  406
               DA P    PGLPG+P +   RA  VVPRYGVR+TVM RP + G
Sbjct  317  SAADARPGVTAPGLPGIPGATLRRAALVVPRYGVRITVMARPPAAG  362


>gi|118466535|ref|YP_883168.1| PPE family protein [Mycobacterium avium 104]
 gi|118167822|gb|ABK68719.1| PPE family protein [Mycobacterium avium 104]
Length=362

 Score =  224 bits (570),  Expect = 3e-56, Method: Compositional matrix adjust.
 Identities = 184/406 (46%), Positives = 225/406 (56%), Gaps = 46/406 (11%)

Query  3    MDFAMLPPEVNSTRMYSGPGAGSLWAAAAAWDQVSAELQSAAETYRSVIASLTGWQWLGP  62
            MDF  LPPEVNS RMY+GPG+GSL AAA +WD ++AEL   A  Y SV+A LTG  W GP
Sbjct  1    MDFGFLPPEVNSARMYAGPGSGSLLAAAGSWDSLAAELSITAAVYESVLAGLTGLYWHGP  60

Query  63   SSVRMGAAVTPYVEWLTTTAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVLSL  122
            +S  M A   PYV WL TTA +A+QTATQ  AAA  +E A AMTVPP A+ ANR Q+ +L
Sbjct  61   ASRAMAAGAAPYVGWLHTTAERAQQTATQARAAAAAYELAHAMTVPPAAVAANRTQLAAL  120

Query  123  IATNFFGQNTAAIAALETQYAEMWEQDATAMYDYAATSAAARTLTPFTSPQQDTNSAGLP  182
            +ATNFFGQNTAAIAA E QYAE W QDA AMY Y+A+SAAA   +PF SP++ T+  G+ 
Sbjct  121  VATNFFGQNTAAIAATEAQYAEYWAQDAAAMYAYSASSAAAAQFSPFASPRRTTDPGGV-  179

Query  183  AQSAEVSRATANAGAADGNWLGNLLEEIGILLLPIAPELTPFFLEAGEIVNAIPFPSIVG  242
                     TA   A      G+   + G  ++P           AG   + IP      
Sbjct  180  ---------TAQQAAVAAAETGSTGTDSGTQVIPP---------TAG--ASEIPL-----  214

Query  243  DEFCLLDGLLAWYATIGSINNINSMGTGIIGAEKNLGILPELGSAAAAAAPPPADIAPAF  302
             +F +LD +L    T  SI     +  GII A+KNLGILP L +  AA    PA      
Sbjct  215  -DFRILDTILGAQTTFRSIFTTEGIPAGIIQADKNLGILPNLATIPAALPRTPA------  267

Query  303  LAPLTSMAKSLSDGALRGPGEVSAAMRGAGTIGQMSVPPAWKAPAVTTVRAFDATPMTTL  362
               L++    L        G + A +  A  IG MSVP  W A     V A   T  +  
Sbjct  268  ---LSASPTGL--------GRIDAVLARAARIGPMSVPAGWTAATGNPVAAAPVTGWSEP  316

Query  363  PGGDA-PAAGVPGLPGMPASGAGRAG-VVPRYGVRLTVMTRPLSGG  406
               DA P    PGLPG+P +   RA  VVPRYGVR+TVM RP + G
Sbjct  317  SAADARPGVTAPGLPGIPGATLRRAALVVPRYGVRITVMARPPAAG  362


>gi|212596159|gb|ACJ35556.1| PPE33 [Mycobacterium avium subsp. avium]
Length=362

 Score =  220 bits (560),  Expect = 4e-55, Method: Compositional matrix adjust.
 Identities = 182/406 (45%), Positives = 224/406 (56%), Gaps = 46/406 (11%)

Query  3    MDFAMLPPEVNSTRMYSGPGAGSLWAAAAAWDQVSAELQSAAETYRSVIASLTGWQWLGP  62
            MDF  LPPEVNS RMY+GPG+GSL AAA +WD ++AEL   A  Y SV+  LTG  W GP
Sbjct  1    MDFGFLPPEVNSARMYAGPGSGSLLAAAGSWDSLAAELSITAAVYESVLGGLTGLYWHGP  60

Query  63   SSVRMGAAVTPYVEWLTTTAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVLSL  122
            +S  M A   PYV WL TTA +A+QTATQ  AAA  +E A AMTVPP A+ ANR Q+ +L
Sbjct  61   ASRAMAAGAAPYVGWLHTTAERAQQTATQARAAAAAYELAHAMTVPPAAVAANRTQLAAL  120

Query  123  IATNFFGQNTAAIAALETQYAEMWEQDATAMYDYAATSAAARTLTPFTSPQQDTNSAGLP  182
            +ATNFFGQNTAAIAA E QYAE W QDA AMY Y+A+SAAA   +PF SP++ T+  G+ 
Sbjct  121  VATNFFGQNTAAIAATEAQYAEYWAQDAAAMYAYSASSAAAAQFSPFASPRRTTDPGGV-  179

Query  183  AQSAEVSRATANAGAADGNWLGNLLEEIGILLLPIAPELTPFFLEAGEIVNAIPFPSIVG  242
                     TA   A      G+   + G  ++P           AG   + IP      
Sbjct  180  ---------TAQQAAVAAAETGSTGTDSGAQVIPP---------TAGG--SEIPL-----  214

Query  243  DEFCLLDGLLAWYATIGSINNINSMGTGIIGAEKNLGILPELGSAAAAAAPPPADIAPAF  302
             +F +LD +L    T  SI     +  GII A++NLGILP L +  AA    PA      
Sbjct  215  -DFRILDTILGAQTTFRSIFTTEGIPAGIIQADENLGILPNLATVPAALPRTPA------  267

Query  303  LAPLTSMAKSLSDGALRGPGEVSAAMRGAGTIGQMSVPPAWKAPAVTTVRAFDATPMTTL  362
               L++    L        G + A +  A  IG MSVP  W A     V A   T  +  
Sbjct  268  ---LSASPTGL--------GRIDAVLARAARIGPMSVPAGWTAATGNPVAAAPVTGWSEP  316

Query  363  PGGDA-PAAGVPGLPGMPASGAGRAG-VVPRYGVRLTVMTRPLSGG  406
               DA P    PGLPG+P +   RA  VVPRYGVR+TVM RP + G
Sbjct  317  SAADARPGVTAPGLPGIPGATLRRAALVVPRYGVRITVMARPPAAG  362


>gi|183982688|ref|YP_001850979.1| PPE family protein, PPE31_1 [Mycobacterium marinum M]
 gi|183176014|gb|ACC41124.1| PPE family protein, PPE31_1 [Mycobacterium marinum M]
Length=422

 Score =  214 bits (546),  Expect = 2e-53, Method: Compositional matrix adjust.
 Identities = 182/435 (42%), Positives = 235/435 (55%), Gaps = 44/435 (10%)

Query  3    MDFAMLPPEVNSTRMYSGPGAGSLWAAAAAWDQVSAELQSAAETYRSVIASLTGWQWLGP  62
            MDFA LPPE+NS RMYSGPG+  + AA  AWD ++AEL+S A  Y +VIA LTG  WLGP
Sbjct  1    MDFAALPPEINSIRMYSGPGSAPMLAAVTAWDGLAAELRSTAAAYETVIAVLTGDGWLGP  60

Query  63   SSVRMGAAVTPYVEWLTTTAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVLSL  122
            +S  M AAV PY+ W+  T  QA QTA Q  AAA  FE AFAMTVPP  + ANR Q+ +L
Sbjct  61   ASESMEAAVFPYLAWMNITGMQAEQTARQAAAAAGAFEAAFAMTVPPAQVAANRTQLQTL  120

Query  123  IATNFFGQNTAAIAALETQYAEMWEQDATAMYDYAATSAAARTLTPFTSPQQDTNSAGLP  182
            +ATN  GQNT AIAA E  Y EMW QDA AMY YA  SAAA TLT FT P Q T+ +GL 
Sbjct  121  VATNLLGQNTPAIAATEAAYGEMWAQDAAAMYGYAVGSAAASTLTQFTQPAQTTDPSGLA  180

Query  183  AQSAEVSRATANAGAADGNWLGNLLE-EIGILLLPIAPELTPFFL-EAGEIVNAIPFPSI  240
            +QSA V++A        G+ +GNL + E+  L+  +   L       A   ++AIP   +
Sbjct  181  SQSAAVTQAV-------GSTVGNLTQTELPQLMSAVPASLQGLASPAAASPIDAIPGSGL  233

Query  241  VGDEFCLLDG-------------LLAWYATIGSINNINSMGTGIIGAEKNLGILPELGSA  287
            +      LDG             L+  + + G ++    +G  I  A  ++  +  LG+ 
Sbjct  234  LAALLNFLDGNDGNPYGVFLNSSLVNGFVSAGYVSPA-VVGPAIWAAMADINAV-ALGAQ  291

Query  288  AAAAAPP--PADIAPAFLAPLTSMAKSLS-------DGALRGPGEVSAAMRGAGTIGQMS  338
             +AA PP    +  P+++ P  S A   S         A  G G +SA M  A  +G+MS
Sbjct  292  ESAAVPPMGSGEGNPSWI-PAASPASPESLPVLGEETAATLGTGGISAGMNQAELVGRMS  350

Query  339  VPPAWKAPAVTTVRAFDA------TPMTTLPGGDAPAAGVPGLPGMPASGAGRA-GVVPR  391
            VP +W         A  A      T    +P     A G+PG+PGMPA   G   G  PR
Sbjct  351  VPQSWGVATAVANHAGAAAPGGGWTSTAVVPEA---AVGMPGIPGMPAGIYGHNLGNAPR  407

Query  392  YGVRLTVMTRPLSGG  406
            YG R T+M RP + G
Sbjct  408  YGFRPTIMGRPPAAG  422


>gi|183982689|ref|YP_001850980.1| PPE family protein [Mycobacterium marinum M]
 gi|183176015|gb|ACC41125.1| PPE family protein [Mycobacterium marinum M]
Length=409

 Score =  205 bits (521),  Expect = 1e-50, Method: Compositional matrix adjust.
 Identities = 180/420 (43%), Positives = 229/420 (55%), Gaps = 32/420 (7%)

Query  3    MDFAMLPPEVNSTRMYSGPGAGSLWAAAAAWDQVSAELQSAAETYRSVIASLTGWQWLGP  62
            MDF  LPPEVNS RMYSGPG+  + AA AAWD VSAE+   A  Y SV+++L    WLGP
Sbjct  6    MDFGALPPEVNSLRMYSGPGSAPMLAAMAAWDDVSAEMLLTAAAYESVLSALLSDGWLGP  65

Query  63   SSVRMGAAVTPYVEWLTTTAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVLSL  122
            +S  M AA  PYV WL+ T  QA QTA Q  AAA  FE AFAMTVPP  + ANR Q+L+L
Sbjct  66   ASAAMAAAAAPYVTWLSATGLQAAQTAGQAAAAAAAFEAAFAMTVPPSVVAANRVQLLTL  125

Query  123  IATNFFGQNTAAIAALETQYAEMWEQDATAMYDYAATSAAARTLTPFTSPQQDTNSAGLP  182
            +ATNF G NT AIAA E +YAEMW QDATAMY YAA SA A TL PF+ P    + +GL 
Sbjct  126  VATNFLGINTPAIAATEAEYAEMWAQDATAMYGYAAGSAVASTLEPFSEPAHTASRSGLA  185

Query  183  AQSAEVSRATANAGAADGNWLGNLLE-EIGILLLPIAPELTPFFLEAGEIVNAIPFPSIV  241
             Q+A V++A + A       +G L + E+  L+  +   L      A   ++ I    ++
Sbjct  186  GQTAAVAQAASTA-------MGGLTQTELPQLMSAVPASLQGLAAPAAAPLDTIAGSGLL  238

Query  242  GDEFCLLDGLLAWYATIGSINNI---NSMGTGIIGAEKNLG--ILPELGSAAAAAAPPPA  296
             D    LDG        G+   I   +S+  G+I A       ++P + SA A       
Sbjct  239  ADILNFLDG------NDGNAFGIFLNSSLANGVISAGYTAPGIVVPAVTSAMADVNALAL  292

Query  297  DIAPAFLAPLTSMAKSLSDGAL--------RGPGEVSAAMRGAGTIGQMSVPPAWKAPAV  348
            D  P    P+T    S S  A+         G G V+A    A  +G++SVPP+W     
Sbjct  293  DGLPGIALPITG---SDSGDAVWTRMTVPQSGLGGVAAGTNQATMVGRLSVPPSWAGTTE  349

Query  349  TTVRAFDATPMTTLPGGDAPAAGVPGLPGMPASGA-GRA-GVVPRYGVRLTVMTRPLSGG  406
             T     A P          +A +PG+PG+PA GA  R+ G  PRYG RLT+M RPLSGG
Sbjct  350  VTDHVATALPGAGTATAPEASAAMPGVPGVPAPGAYARSYGTGPRYGFRLTIMPRPLSGG  409


>gi|183981114|ref|YP_001849405.1| PPE family protein [Mycobacterium marinum M]
 gi|183174440|gb|ACC39550.1| PPE family protein [Mycobacterium marinum M]
Length=380

 Score =  199 bits (506),  Expect = 8e-49, Method: Compositional matrix adjust.
 Identities = 163/411 (40%), Positives = 211/411 (52%), Gaps = 38/411 (9%)

Query  3    MDFAMLPPEVNSTRMYSGPGAGSLWAAAAAWDQVSAELQSAAETYRSVIASLTGWQWLGP  62
            MDF +LPPE+NS RMYSGPG+  L   A+AW  ++AEL + A  Y +VI+ L    W+GP
Sbjct  1    MDFGILPPEINSARMYSGPGSSPLLTVASAWSGLAAELSATANDYETVISGLQSQGWVGP  60

Query  63   SSVRMGAAVTPYVEWLTTTAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVLSL  122
            SS  M  ++ PYV WL  TAA   Q+A++   AA+ +E AFA TVPPP I ANRA++  L
Sbjct  61   SSEAMANSIWPYVAWLRATAAATEQSASKARIAASAYEAAFAATVPPPQIAANRAELTGL  120

Query  123  IATNFFGQNTAAIAALETQYAEMWEQDATAMYDYAATSAAARTLTPFTSPQQDTNSAGLP  182
            I+TN  GQN+AAIAA E QY EMW QDA  MY YAA+ A A +LTPF SP Q TN     
Sbjct  121  ISTNVVGQNSAAIAAAEAQYGEMWSQDAATMYAYAASCATATSLTPFVSPPQTTNPTAAA  180

Query  183  AQSAEVSRATANAGAADGNWLGNLLEEI-GILLLPIAPELTPFFLEAGEIVNAIPFPSIV  241
             Q+  +SRA A       + L  L+ E+ G+L    +P  +     AG I          
Sbjct  181  TQAGTLSRAAATTTGTAQSTLSRLISEVPGVLQALTSPLASAASSTAGPI----------  230

Query  242  GDEFCLLDGLLAWYATIGSINNINSMGTGIIGAEKNLGILPELGSAAAAAAPPPADIAPA  301
                   +  L WYA   +    +++G    GA    GI     + A  A          
Sbjct  231  -------ERFLEWYAPFANF-FYDTLGLPFFGA----GITSFFAATAKTAG-----AIGP  273

Query  302  FLAPLTSMAKSLSDGALRGPGEVSAAMRGAGTIGQMSVPPAWK----APAVTTVRAF--D  355
              A   +   +       G G VSA++  A T+G++SVP  W+    A + TT   F  D
Sbjct  274  AAAAPAATVAATGAAEAVGAGPVSASLAQASTVGKLSVPHTWEGATPATSPTTASKFISD  333

Query  356  ATPMTTLPGGDAPAAGVPGLPGMPASGAGRAGVVPRYGVRLTVMTRPLSGG  406
                 ++  G     GVP    MP  G G AG  PRYGVRLTVM  P S G
Sbjct  334  VIEPESVEAGGNVIGGVP----MPGPGKGSAGAGPRYGVRLTVMPHPPSAG  380


>gi|296167733|ref|ZP_06849950.1| PPE family protein [Mycobacterium parascrofulaceum ATCC BAA-614]
 gi|295897076|gb|EFG76691.1| PPE family protein [Mycobacterium parascrofulaceum ATCC BAA-614]
Length=406

 Score =  198 bits (503),  Expect = 1e-48, Method: Compositional matrix adjust.
 Identities = 167/427 (40%), Positives = 214/427 (51%), Gaps = 43/427 (10%)

Query  2    FMDFAMLPPEVNSTRMYSGPGAGSLWAAAAAWDQVSAELQSAAETYRSVIASLTGWQWLG  61
             +DF   PPE NS RMY+GPG  +L AAA+AW+ ++AEL S A  Y  VI +L+G +WLG
Sbjct  1    MIDFGAAPPEYNSARMYTGPGPEALTAAASAWNGLAAELNSTALGYDKVITALSGEEWLG  60

Query  62   PSSVRMGAAVTPYVEWLTTTAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVLS  121
            P+S  M  AV PYV W+ TTAAQA QTA Q+ AAAT +E A A TVPPP + ANRAQ   
Sbjct  61   PASASMAQAVAPYVAWMRTTAAQAEQTANQMHAAATAYETALAATVPPPLVAANRAQTAQ  120

Query  122  LIATNFFGQNTAAIAALETQYAEMWEQDATAMYDYAATSAAARTLTPFTSPQQDTNSAGL  181
            L+ATN  G NT AIA LE QY EMW QDA+ MY YA  SAAA  + PFT+  Q  N +  
Sbjct  121  LLATNVLGLNTPAIAQLEAQYGEMWAQDASTMYSYAGQSAAATKVAPFTAAPQIANPSAQ  180

Query  182  PAQSAEVSRATANAGAAD-----GNWLGNLLEEIGILLLPIAPELT----PF----FLEA  228
              Q   V+ AT N+ A+       + + +    +  L  P A + +    PF    +L  
Sbjct  181  ATQGTAVANATGNSAASSTQSVLSHAVSSTPNTLQALAAPAATQSSTTSAPFSEIWYLLT  240

Query  229  GEIVNAIPFPSIVG--DEFCLLDGLLAWYATIGSINNINSMGTGIIGAEKNLGILPELGS  286
            G+        S V   + F  L     WY T G       MG   +   K  G+L     
Sbjct  241  GQTTLPTSLGSFVNGYNPFSAL-----WYNTEGLPYFSVGMGNFGVQIAKTTGLL-----  290

Query  287  AAAAAAPPPADIAPAFLAPLTSMAKSLSDGALRGPGEVSAAMRGAGTI-GQMSVPPAWKA  345
                        APA  A           G        +AA+  A ++ G++SVP +W A
Sbjct  291  ---------NGAAPAVKALPGLGGLGGLLGGGATAAHPAAALGNAASVGGRLSVPVSWSA  341

Query  346  PAVTTVRAFDATPMTTLPGG-DAPAAGVPG-----LPGMPASGAGRAGVVPRYGVRLTVM  399
             +        A P++T+    DA AA  PG     +P   A   G AGV P+YG R TVM
Sbjct  342  ASTPAPVLGQAIPVSTVSAAPDATAA--PGNLLGGMPLAGAGAGGHAGVGPKYGFRPTVM  399

Query  400  TRPLSGG  406
             RP  GG
Sbjct  400  ARPPFGG  406


>gi|342861033|ref|ZP_08717682.1| PPE family protein [Mycobacterium colombiense CECT 3035]
 gi|342131477|gb|EGT84747.1| PPE family protein [Mycobacterium colombiense CECT 3035]
Length=376

 Score =  196 bits (499),  Expect = 5e-48, Method: Compositional matrix adjust.
 Identities = 165/398 (42%), Positives = 213/398 (54%), Gaps = 30/398 (7%)

Query  17   MYSGPGAGSLWAAAAAWDQVSAELQSAAETYRSVIASLTGWQWLGPSSVRMGAAVTPYVE  76
            MY+GPG  SL AAA +WD +SAEL S AE+Y SV+  L G QW GP++  M  +   Y+ 
Sbjct  1    MYTGPGLASLLAAAGSWDALSAELASTAESYESVLVGL-GLQWRGPAAESMAYSAARYMG  59

Query  77   WLTTTAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVLSLIATNFFGQNTAAIA  136
            WL  TA Q +QTA Q   AA  +EQA++MTVPPP I ANR  + SL+ATN  GQNTAAIA
Sbjct  60   WLEATAEQTKQTAMQARTAAAAYEQAYSMTVPPPVIAANRTLLASLVATNIVGQNTAAIA  119

Query  137  ALETQYAEMWEQDATAMYDYAATSAAARTLTP-FTSPQQDTNSAGLPAQSAEVSRATANA  195
              E QY++ W QDA AM  Y+A+S  A    P F +  + T  +G+ AQ+A V+ A  NA
Sbjct  120  DTEAQYSDFWAQDAAAMAGYSASSTVATAQLPRFATANKSTTESGVSAQNAAVATANTNA  179

Query  196  GAADGNWLGNLLEEIGILLLPIAPELTP---FFLEAGEIVNAIPFPSIVGDEFCLLDGLL  252
            GA            +     P  P  TP   ++L+A    +         + F +LD + 
Sbjct  180  GAT--KVAAQTFSPLDT--SPTGPGSTPGDIYYLDASTTSSGT-------NAFRVLDAIQ  228

Query  253  AWYATIGSINNINSMGTGIIGAEKNLGILPELGSAAAAAAPPPADIAPAFLAPLTSMAKS  312
                   +  N+    +GIIGAE NLGIL          A P A  A    A      + 
Sbjct  229  GTSLGFTAPYNMEQFVSGIIGAENNLGIL----------AKPGAAAANLAPAIAAPALRG  278

Query  313  LSDGALRGPGEVSAAMRGAGTIGQMSVPPAWKAPAVTTVRAFDATPMTTLPGGDAPAAG-  371
             + G   G G V+A +  AGTIG MSVP +W AP  T +   +    TT+PG + P A  
Sbjct  279  ATAGLGGGLGNVTATLSHAGTIGPMSVPASWAAPTSTHISPLEPAGFTTIPGTEEPVASG  338

Query  372  ---VPGLPGMPASGAGRAGVVPRYGVRLTVMTRPLSGG  406
                PGLPG  A+ +  AGV PRYGVRLTVM RP + G
Sbjct  339  YPGYPGLPGGGAARSAGAGVPPRYGVRLTVMPRPPAAG  376


>gi|240169314|ref|ZP_04747973.1| PPE family protein [Mycobacterium kansasii ATCC 12478]
Length=383

 Score =  192 bits (489),  Expect = 7e-47, Method: Compositional matrix adjust.
 Identities = 107/183 (59%), Positives = 128/183 (70%), Gaps = 0/183 (0%)

Query  3    MDFAMLPPEVNSTRMYSGPGAGSLWAAAAAWDQVSAELQSAAETYRSVIASLTGWQWLGP  62
            MDF  LPPEVNS RMY+GPG GSL AAA  WD ++AEL + A  YRSVIA LT  +WLGP
Sbjct  1    MDFGALPPEVNSVRMYAGPGPGSLAAAAGMWDSLAAELHATAGHYRSVIAGLTSGRWLGP  60

Query  63   SSVRMGAAVTPYVEWLTTTAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVLSL  122
            +S+ M +A+ PYV W    AA+A +TA+Q   A  G+E AFAMTVPPP + ANRA + +L
Sbjct  61   ASLSMASALGPYVAWTAGVAARAAETASQAVLAVEGYEAAFAMTVPPPVVAANRALLAAL  120

Query  123  IATNFFGQNTAAIAALETQYAEMWEQDATAMYDYAATSAAARTLTPFTSPQQDTNSAGLP  182
            +ATNFFGQN+ AIAA E +Y  MW QDA AMY+YAA SA A  LT   SP +  N  GL 
Sbjct  121  VATNFFGQNSTAIAATEAEYGVMWAQDAAAMYEYAANSATACELTLLISPPEVINPVGLA  180

Query  183  AQS  185
             QS
Sbjct  181  GQS  183


>gi|212596661|gb|ACJ35596.1| PPE32 [Mycobacterium intracellulare ATCC 13950]
Length=391

 Score =  192 bits (488),  Expect = 1e-46, Method: Compositional matrix adjust.
 Identities = 180/411 (44%), Positives = 230/411 (56%), Gaps = 27/411 (6%)

Query  3    MDFAMLPPEVNSTRMYSGPGAGSLWAAAAAWDQVSAELQSAAETYRSVIASLTGWQWLGP  62
            MD+A +PPE+NS RMY+GPG GSL AAA +WD +SAEL SAAE Y S ++ L   QW GP
Sbjct  1    MDWAFVPPEINSARMYTGPGMGSLLAAAGSWDALSAELSSAAEGYESALSGL-DLQWRGP  59

Query  63   SSVRMGAAVTPYVEWLTTTAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVLSL  122
            ++  M  A   Y EWL  TA Q RQTA Q   AA  +EQA+AMTVPPP I ANR  + +L
Sbjct  60   AAQAMAFAAIRYAEWLQVTAEQTRQTAMQARTAAAAYEQAYAMTVPPPVITANRTLLAAL  119

Query  123  IATNFFGQNTAAIAALETQYAEMWEQDATAMYDYAATSAAARTLTPFTSPQQDTNSAGLP  182
            +A+N  GQNTAAIA  E QYA+ W QDA AM  Y+ +SAAA  L  F      TN +G+ 
Sbjct  120  VASNIVGQNTAAIADTEAQYADYWAQDAAAMSAYSVSSAAATQLPRFAPATNSTNESGVS  179

Query  183  AQSAEVSRATANAGAADGNWLGNLLEEIGILLLPIAPELT-PFFLEAGEIVNAIPFPSIV  241
            AQ A V+ A +NA A          + +     P++ + T   +   G+I +     +  
Sbjct  180  AQKAAVTAANSNAAAN---------KAVTQSYSPLSTQQTGDTYNYYGDIYDLSDTTAAA  230

Query  242  GDE--FCLLDGLLAWYATIGSINNINSMGTGIIGAEKNLGILPELGSAAAAAAPPPADIA  299
            G +  F  LD +        +  N+    +GIIGAE NLGIL +  +AA A A       
Sbjct  231  GGKPFFAALDAIQGTGVGFSAPYNMEQFVSGIIGAENNLGILAKPLAAAPALA-------  283

Query  300  PAFLAPLTSMAKSLSDGALRGPGEVSAAMRGAGTIGQMSVPPAWKAPAVTTVRAFDATPM  359
                  L+S   SL  G   G G V+A +  AG+IG MSVP +W AP  T +   +    
Sbjct  284  ---APALSSTTTSLGGGLGAGLGNVTATLSHAGSIGPMSVPASWAAPTSTHISPLEPAGF  340

Query  360  TTLPGGDAPAAG----VPGLPGMPASGAGRAGVVPRYGVRLTVMTRPLSGG  406
            TTLPG + P A      PG+PG  AS +  AGV PRYGVRLTVM RP + G
Sbjct  341  TTLPGTEEPVASGYPGYPGMPGGGASRSVGAGVPPRYGVRLTVMPRPPAAG  391


>gi|118618459|ref|YP_906791.1| PPE family protein [Mycobacterium ulcerans Agy99]
 gi|118570569|gb|ABL05320.1| PPE family protein [Mycobacterium ulcerans Agy99]
Length=450

 Score =  192 bits (487),  Expect = 1e-46, Method: Compositional matrix adjust.
 Identities = 156/365 (43%), Positives = 204/365 (56%), Gaps = 34/365 (9%)

Query  3    MDFAMLPPEVNSTRMYSGPGAGSLWAAAAAWDQVSAELQSAAETYRSVIASLTGWQWLGP  62
            MDFA LPPE+N  RMYSGPG+  + AA  AWD ++AEL+S A  Y +VIA LTG  WLGP
Sbjct  1    MDFAALPPEINPIRMYSGPGSAPMLAAVTAWDGLAAELRSTAAAYETVIAVLTGDGWLGP  60

Query  63   SSVRMGAAVTPYVEWLTTTAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVLSL  122
            +S  M AAV PY+ W+  T  QA QTA Q  AAA  FE AFAMTVPP  + ANR Q+ +L
Sbjct  61   ASESMEAAVFPYLAWMNITGMQAEQTARQAAAAAGAFEAAFAMTVPPAQVAANRTQLQTL  120

Query  123  IATNFFGQNTAAIAALETQYAEMWEQDATAMYDYAATSAAARTLTPFTSPQQDTNSAGLP  182
            +ATN  GQNT AIAA E  Y EMW QDA AMY YA  SAAA TLT FT P Q T+ +GL 
Sbjct  121  VATNLLGQNTPAIAATEAAYGEMWAQDAAAMYGYAVGSAAASTLTQFTQPAQTTDPSGLA  180

Query  183  AQSAEVSRATANAGAADGNWLGNLLE-EIGILLLPIAPELTPFFL-EAGEIVNAIPFPSI  240
            +QSA V++A        G+ +GNL + E+  L+  +   L       A   ++AIP   +
Sbjct  181  SQSAAVTQAV-------GSTVGNLTQTELPQLMSAVPASLQGLASPAAASPIDAIPGSGL  233

Query  241  VGDEFCLLDG-------------LLAWYATIGSINNINSMGTGIIGAEKNLGILPELGSA  287
            +      LDG             L+  + + G ++    +G  I  A  ++  +  LG+ 
Sbjct  234  LAALLNFLDGNDGNPYGVFLNSSLVNGFVSAGYVSPA-VVGPAIWAAMADINAV-ALGAQ  291

Query  288  AAAAAPP--PADIAPAFLAPLTSMAKSLS-------DGALRGPGEVSAAMRGAGTIGQMS  338
             +AA PP    +  P+++ P  S A   S         A  G G +SA M  A  +G+MS
Sbjct  292  ESAAVPPMGSGEGNPSWI-PAASPASPESLPVLGEETAATLGTGGISAGMNQAELVGRMS  350

Query  339  VPPAW  343
            VP +W
Sbjct  351  VPQSW  355


>gi|57116920|ref|YP_177653.1| PPE family protein [Mycobacterium tuberculosis H37Rv]
 gi|38684069|emb|CAE55432.1| PPE FAMILY PROTEIN [Mycobacterium tuberculosis H37Rv]
Length=399

 Score =  192 bits (487),  Expect = 1e-46, Method: Compositional matrix adjust.
 Identities = 180/429 (42%), Positives = 228/429 (54%), Gaps = 55/429 (12%)

Query  3    MDFAMLPPEVNSTRMYSGPGAGSLWAAAAAWDQVSAELQSAAETYRSVIASLTGWQWLGP  62
            +DFA LPPE+NS RMYSG G+  + AAA+AW  +SAEL+++A +Y SV+++LTG +W GP
Sbjct  1    LDFATLPPEINSARMYSGAGSAPMLAAASAWHGLSAELRASALSYSSVLSTLTGEEWHGP  60

Query  63   SSVRMGAAVTPYVEWLTTTAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVLSL  122
            +S  M AA  PYV W++ TA +A Q   Q  AAA  +E AFA TVPPP I ANRAQ+++L
Sbjct  61   ASASMTAAAAPYVAWMSVTAVRAEQAGAQAEAAAAAYEAAFAATVPPPVIEANRAQLMAL  120

Query  123  IATNFFGQNTAAIAALETQYAEMWEQDATAMYDYAATSAAARTLTPFTSPQQDTNSAGLP  182
            IATN  GQN  AIAA E QYAEMW QDA AMY YA  SAAA  LTPFT P Q TN++GL 
Sbjct  121  IATNVLGQNAPAIAATEAQYAEMWSQDAMAMYGYAGASAAATQLTPFTEPVQTTNASGLA  180

Query  183  AQSAEVSRATANAGAADGNWLGNLLEEIGILLLPIAPELTPFFLEAGEIVNAIPFPS---  239
            AQSA ++ AT  +  A    L  L+  I            P  L+      A  F S   
Sbjct  181  AQSAAIAHATGASAGAQQTTLSQLIAAI------------PSVLQGLSSSTAATFASGPS  228

Query  240  ----IVGDEFCLLDGLLAWYATIGSINNINSMGTGIIGAEKN-----LGIL---------  281
                IVG     LD L  W     + N  N++ +  +    N     LG+L         
Sbjct  229  GLLGIVGSGSSWLDKL--WALLDPNSNFWNTIASSGLFLPSNTIAPFLGLLGGVAAADAA  286

Query  282  -PELGSAAAAAAPPPADIAPAFLAPLTSMAKSLSDGALRGPGEVSAAMRGAGTIGQMSVP  340
               LG A +        +  A +APL       S G L   G V+A +  A T+G +SVP
Sbjct  287  GDVLGEATS------GGLGGALVAPLG------SAGGLG--GTVAAGLGNAATVGTLSVP  332

Query  341  PAWKAPAVTTV---RAFDATPMTTLPGGDAPAAGVPGLPGMPASGAGRAGVVPRYGVRLT  397
            P+W A A        A   TPM   P   A AAG+PG+P     G G    VP+YG R  
Sbjct  333  PSWTAAAPLASPLGSALGGTPMVAPP--PAVAAGMPGMPFGTMGGQGFGRAVPQYGFRPN  390

Query  398  VMTRPLSGG  406
             + RP + G
Sbjct  391  FVARPPAAG  399


>gi|148661613|ref|YP_001283136.1| PPE family protein [Mycobacterium tuberculosis H37Ra]
 gi|167967398|ref|ZP_02549675.1| PPE family protein [Mycobacterium tuberculosis H37Ra]
 gi|307084422|ref|ZP_07493535.1| PPE family protein [Mycobacterium tuberculosis SUMu012]
 gi|7478807|pir||H70931 probable PPE protein - Mycobacterium tuberculosis (strain H37RV)
 gi|148505765|gb|ABQ73574.1| PPE family protein [Mycobacterium tuberculosis H37Ra]
 gi|308365982|gb|EFP54833.1| PPE family protein [Mycobacterium tuberculosis SUMu012]
Length=403

 Score =  191 bits (486),  Expect = 1e-46, Method: Compositional matrix adjust.
 Identities = 180/429 (42%), Positives = 228/429 (54%), Gaps = 55/429 (12%)

Query  3    MDFAMLPPEVNSTRMYSGPGAGSLWAAAAAWDQVSAELQSAAETYRSVIASLTGWQWLGP  62
            +DFA LPPE+NS RMYSG G+  + AAA+AW  +SAEL+++A +Y SV+++LTG +W GP
Sbjct  5    LDFATLPPEINSARMYSGAGSAPMLAAASAWHGLSAELRASALSYSSVLSTLTGEEWHGP  64

Query  63   SSVRMGAAVTPYVEWLTTTAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVLSL  122
            +S  M AA  PYV W++ TA +A Q   Q  AAA  +E AFA TVPPP I ANRAQ+++L
Sbjct  65   ASASMTAAAAPYVAWMSVTAVRAEQAGAQAEAAAAAYEAAFAATVPPPVIEANRAQLMAL  124

Query  123  IATNFFGQNTAAIAALETQYAEMWEQDATAMYDYAATSAAARTLTPFTSPQQDTNSAGLP  182
            IATN  GQN  AIAA E QYAEMW QDA AMY YA  SAAA  LTPFT P Q TN++GL 
Sbjct  125  IATNVLGQNAPAIAATEAQYAEMWSQDAMAMYGYAGASAAATQLTPFTEPVQTTNASGLA  184

Query  183  AQSAEVSRATANAGAADGNWLGNLLEEIGILLLPIAPELTPFFLEAGEIVNAIPFPS---  239
            AQSA ++ AT  +  A    L  L+  I            P  L+      A  F S   
Sbjct  185  AQSAAIAHATGASAGAQQTTLSQLIAAI------------PSVLQGLSSSTAATFASGPS  232

Query  240  ----IVGDEFCLLDGLLAWYATIGSINNINSMGTGIIGAEKN-----LGIL---------  281
                IVG     LD L  W     + N  N++ +  +    N     LG+L         
Sbjct  233  GLLGIVGSGSSWLDKL--WALLDPNSNFWNTIASSGLFLPSNTIAPFLGLLGGVAAADAA  290

Query  282  -PELGSAAAAAAPPPADIAPAFLAPLTSMAKSLSDGALRGPGEVSAAMRGAGTIGQMSVP  340
               LG A +        +  A +APL       S G L   G V+A +  A T+G +SVP
Sbjct  291  GDVLGEATS------GGLGGALVAPLG------SAGGLG--GTVAAGLGNAATVGTLSVP  336

Query  341  PAWKAPAVTTV---RAFDATPMTTLPGGDAPAAGVPGLPGMPASGAGRAGVVPRYGVRLT  397
            P+W A A        A   TPM   P   A AAG+PG+P     G G    VP+YG R  
Sbjct  337  PSWTAAAPLASPLGSALGGTPMVAPP--PAVAAGMPGMPFGTMGGQGFGRAVPQYGFRPN  394

Query  398  VMTRPLSGG  406
             + RP + G
Sbjct  395  FVARPPAAG  403


>gi|289574372|ref|ZP_06454599.1| PPE family protein [Mycobacterium tuberculosis K85]
 gi|289538803|gb|EFD43381.1| PPE family protein [Mycobacterium tuberculosis K85]
Length=384

 Score =  191 bits (484),  Expect = 3e-46, Method: Compositional matrix adjust.
 Identities = 160/414 (39%), Positives = 212/414 (52%), Gaps = 48/414 (11%)

Query  3    MDFAMLPPEVNSTRMYSGPGAGSLWAAAAAWDQVSAELQSAAETYRSVIASLTGWQWLGP  62
            MDF  LPPEVNS RMY GPG+  + AAA+AW+ ++AEL  AA  Y  VI +L   +WLGP
Sbjct  1    MDFGALPPEVNSGRMYCGPGSAPMVAAASAWNGLAAELSVAAVGYERVITTLQTEEWLGP  60

Query  63   SSVRMGAAVTPYVEWLTTTAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVLSL  122
            +S  M  AV PYV W+  TA QA Q A+Q  AAA  +E AFA  VPPP I ANRA++ SL
Sbjct  61   ASTLMVEAVAPYVAWMRATAIQAEQAASQARAAAAAYETAFAAIVPPPLIAANRARLTSL  120

Query  123  IATNFFGQNTAAIAALETQYAEMWEQDATAMYDYAATSAAARTLTPFTSPQQDTNSAGLP  182
            +  N FGQNTA+IAA E QYAEMW QDA AMY YA +SA A  +TPF  P   T+ +   
Sbjct  121  VTHNVFGQNTASIAATEAQYAEMWAQDAMAMYGYAGSSATATKVTPFAPPPNTTSPSAAA  180

Query  183  AQSAEVSRATANAGAADGNWLGNLLEEIGILLLPIAPELTPFFLEAGEIVNAIPFPSIVG  242
             Q + V++A   +  A  + +  L+  +   LL +   L+     A     A P      
Sbjct  181  TQLSAVAKAAGTSAGAAQSAIAELIAHLPNTLLGLTSPLSSALTAA-----ATP------  229

Query  243  DEFCLLDGLLAWYATIGSI--NNIN------SMGTGIIGAEKNLGILPELGSAAAAAAPP  294
                 L+  + WY  I  +  N +        +G  +I + + LG +   G  +  AA  
Sbjct  230  ---GWLEWFINWYLPISQLFYNTVGLPYFAIGIGNSLITSWRALGWIGSRGRRSCRAARR  286

Query  295  PADIAPAFLAPLTSMAKSLSDGALRGPGEVSAAMRGAGTIGQMSVPPAWK------APAV  348
            P                      + G G VSA +  A TIG++SVPP W       AP V
Sbjct  287  P-------------------SARVCGTGPVSAGLGNAATIGKLSVPPNWAGASPSLAPTV  327

Query  349  TTVRAFDATPMTTLPGGDAPAAGVPGLPGMPASGAGRAGVVPRYGVRLTVMTRP  402
             +  A   + +   P   A    + G+P +  SG G  G  PRYG R+TVM+RP
Sbjct  328  GSASAPLVSDIVEQPEAGAAGNLLGGMP-LAGSGTGTGGAGPRYGFRVTVMSRP  380


>gi|289759264|ref|ZP_06518642.1| PPE family protein [Mycobacterium tuberculosis T85]
 gi|289714828|gb|EFD78840.1| PPE family protein [Mycobacterium tuberculosis T85]
 gi|326902641|gb|EGE49574.1| PPE family protein [Mycobacterium tuberculosis W-148]
 gi|339295969|gb|AEJ48080.1| PPE family protein [Mycobacterium tuberculosis CCDC5079]
 gi|339299578|gb|AEJ51688.1| PPE family protein [Mycobacterium tuberculosis CCDC5180]
Length=262

 Score =  190 bits (483),  Expect = 3e-46, Method: Compositional matrix adjust.
 Identities = 128/193 (67%), Positives = 147/193 (77%), Gaps = 0/193 (0%)

Query  3    MDFAMLPPEVNSTRMYSGPGAGSLWAAAAAWDQVSAELQSAAETYRSVIASLTGWQWLGP  62
            MD+A LPPE+NS RMYSGPG  S+  AAA+WD ++AEL SAAE Y SVIA LTG  W GP
Sbjct  1    MDYAFLPPEINSARMYSGPGPNSMLVAAASWDALAAELASAAENYGSVIARLTGMHWWGP  60

Query  63   SSVRMGAAVTPYVEWLTTTAAQARQTATQITAAATGFEQAFAMTVPPPAIMANRAQVLSL  122
            +S  M A   PYVEWL  TAAQ +QTATQ  AAA  FEQA AMTVPP  + ANRA++ +L
Sbjct  61   ASTSMLAMSAPYVEWLERTAAQTKQTATQARAAAAAFEQAHAMTVPPALVTANRAELKAL  120

Query  123  IATNFFGQNTAAIAALETQYAEMWEQDATAMYDYAATSAAARTLTPFTSPQQDTNSAGLP  182
            IA+N  GQNTAAIAA+E QYAEMW QDA AMY YA TSAAAR LTPF+SPQQ TN AGL 
Sbjct  121  IASNLLGQNTAAIAAIEAQYAEMWAQDAAAMYGYATTSAAARQLTPFSSPQQTTNPAGLA  180

Query  183  AQSAEVSRATANA  195
            AQ+A V++A  N+
Sbjct  181  AQNAAVTQAATNS  193



Lambda     K      H
   0.315    0.129    0.385 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Effective search space used: 807118285248


  Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
    Posted date:  Sep 5, 2011  4:36 AM
  Number of letters in database: 5,219,829,388
  Number of sequences in database:  15,229,318



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40