BLASTP 2.2.25+
Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
15,229,318 sequences; 5,219,829,388 total letters
Query= Rv3534c
Length=346
Score E
Sequences producing significant alignments: (Bits) Value
gi|15610670|ref|NP_218051.1| 4-hydroxy-2-ketovalerate aldolase [... 697 0.0
gi|254366099|ref|ZP_04982143.1| hypothetical 4-hydroxy-2-oxovale... 695 0.0
gi|15843146|ref|NP_338183.1| 4-hydroxy-2-ketovalerate aldolase [... 691 0.0
gi|340628498|ref|YP_004746950.1| putative 4-hydroxy-2-oxovalerat... 685 0.0
gi|240172367|ref|ZP_04751026.1| 4-hydroxy-2-ketovalerate aldolas... 672 0.0
gi|183984989|ref|YP_001853280.1| 4-hydroxy-2-oxovalerate aldolas... 659 0.0
gi|118619280|ref|YP_907612.1| 4-hydroxy-2-ketovalerate aldolase ... 654 0.0
gi|296166563|ref|ZP_06848993.1| 4-hydroxy-2-oxovalerate aldolase... 652 0.0
gi|108801622|ref|YP_641819.1| 4-hydroxy-2-ketovalerate aldolase ... 649 0.0
gi|126437606|ref|YP_001073297.1| 4-hydroxy-2-ketovalerate aldola... 649 0.0
gi|118462327|ref|YP_879907.1| 4-hydroxy-2-ketovalerate aldolase ... 645 0.0
gi|254822616|ref|ZP_05227617.1| 4-hydroxy-2-ketovalerate aldolas... 645 0.0
gi|145222114|ref|YP_001132792.1| 4-hydroxy-2-ketovalerate aldola... 645 0.0
gi|126436796|ref|YP_001072487.1| 4-hydroxy-2-ketovalerate aldola... 645 0.0
gi|41406631|ref|NP_959467.1| 4-hydroxy-2-ketovalerate aldolase [... 643 0.0
gi|342862266|ref|ZP_08718908.1| 4-hyroxy-2-oxovalerate/4-hydroxy... 643 0.0
gi|342860635|ref|ZP_08717285.1| 4-hyroxy-2-oxovalerate/4-hydroxy... 641 0.0
gi|254820084|ref|ZP_05225085.1| 4-hydroxy-2-ketovalerate aldolas... 641 0.0
gi|120406182|ref|YP_956011.1| 4-hydroxy-2-ketovalerate aldolase ... 640 0.0
gi|118469867|ref|YP_890164.1| 4-hydroxy-2-ketovalerate aldolase ... 635 4e-180
gi|169627729|ref|YP_001701378.1| 4-hydroxy-2-ketovalerate aldola... 602 4e-170
gi|333992319|ref|YP_004524933.1| 4-hydroxy-2-oxovalerate aldolas... 597 1e-168
gi|226304230|ref|YP_002764188.1| 4-hydroxy-2-oxovalerate aldolas... 582 4e-164
gi|226363860|ref|YP_002781642.1| 4-hydroxy-2-ketovalerate aldola... 582 4e-164
gi|111021507|ref|YP_704479.1| 4-hydroxy-2-ketovalerate aldolase ... 581 5e-164
gi|241992735|gb|ACS73886.1| HsaF [Rhodococcus ruber] 579 2e-163
gi|229494382|ref|ZP_04388145.1| 4-hydroxy-2-oxovalerate aldolase... 578 4e-163
gi|238481729|gb|ACR43932.1| 4-hydroxy-2-oxovalerate aldolase [Rh... 564 6e-159
gi|54022431|ref|YP_116673.1| 4-hydroxy-2-ketovalerate aldolase [... 564 7e-159
gi|262200908|ref|YP_003272116.1| 4-hydroxy-2-oxovalerate aldolas... 555 6e-156
gi|343925861|ref|ZP_08765376.1| putative 4-hydroxy-2-oxovalerate... 545 6e-153
gi|319948620|ref|ZP_08022744.1| 4-hyroxy-2-oxovalerate/4-hydroxy... 538 4e-151
gi|269127676|ref|YP_003301046.1| 4-hydroxy-2-oxovalerate aldolas... 534 1e-149
gi|111022764|ref|YP_705736.1| 4-hydroxy-2-ketovalerate aldolase ... 513 1e-143
gi|311744294|ref|ZP_07718098.1| 4-hydroxy-2-oxovalerate aldolase... 513 1e-143
gi|226365271|ref|YP_002783054.1| 4-hydroxy-2-ketovalerate aldola... 513 1e-143
gi|284041912|ref|YP_003392252.1| 4-hydroxy-2-oxovalerate aldolas... 457 1e-126
gi|317124230|ref|YP_004098342.1| 4-hydroxy-2-oxovalerate aldolas... 425 4e-117
gi|296141474|ref|YP_003648717.1| 4-hydroxy-2-oxovalerate aldolas... 425 6e-117
gi|333918691|ref|YP_004492272.1| 4-hydroxy-2-oxovalerate aldolas... 424 7e-117
gi|302527630|ref|ZP_07279972.1| 4-hydroxy-2-oxovalerate aldolase... 422 4e-116
gi|269124801|ref|YP_003298171.1| 4-hydroxy-2-oxovalerate aldolas... 409 5e-112
gi|297154944|gb|ADI04656.1| 4-hydroxy-2-ketovalerate aldolase [S... 408 8e-112
gi|258654204|ref|YP_003203360.1| 4-hydroxy-2-ketovalerate aldola... 402 4e-110
gi|300786106|ref|YP_003766397.1| 4-hydroxy-2-ketovalerate aldola... 402 6e-110
gi|111025801|ref|YP_708221.1| 4-hydroxy-2-ketovalerate aldolase ... 399 5e-109
gi|302546957|ref|ZP_07299299.1| 4-hydroxy-2-oxovalerate aldolase... 397 1e-108
gi|331697956|ref|YP_004334195.1| 4-hydroxy-2-oxovalerate aldolas... 381 1e-103
gi|296119335|ref|ZP_06837903.1| 4-hydroxy-2-oxovalerate aldolase... 379 3e-103
gi|288921462|ref|ZP_06415739.1| 4-hydroxy-2-oxovalerate aldolase... 379 5e-103
>gi|15610670|ref|NP_218051.1| 4-hydroxy-2-ketovalerate aldolase [Mycobacterium tuberculosis
H37Rv]
gi|31794710|ref|NP_857203.1| 4-hydroxy-2-ketovalerate aldolase [Mycobacterium bovis AF2122/97]
gi|121639453|ref|YP_979677.1| 4-hydroxy-2-ketovalerate aldolase [Mycobacterium bovis BCG str.
Pasteur 1173P2]
75 more sequence titles
Length=346
Score = 697 bits (1798), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 346/346 (100%), Positives = 346/346 (100%), Gaps = 0/346 (0%)
Query 1 MTDMWDVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNY 60
MTDMWDVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNY
Sbjct 1 MTDMWDVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNY 60
Query 61 GFSKTPEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVS 120
GFSKTPEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVS
Sbjct 61 GFSKTPEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVS 120
Query 121 IQHFGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVAD 180
IQHFGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVAD
Sbjct 121 IQHFGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVAD 180
Query 181 RVSALVAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEAL 240
RVSALVAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEAL
Sbjct 181 RVSALVAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEAL 240
Query 241 IGVFDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQA 300
IGVFDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQA
Sbjct 241 IGVFDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQA 300
Query 301 ERYGVPASALLHRAGQRKLIGGQEDQLIDIALEIKRELDSGAAVTH 346
ERYGVPASALLHRAGQRKLIGGQEDQLIDIALEIKRELDSGAAVTH
Sbjct 301 ERYGVPASALLHRAGQRKLIGGQEDQLIDIALEIKRELDSGAAVTH 346
>gi|254366099|ref|ZP_04982143.1| hypothetical 4-hydroxy-2-oxovalerate aldolase [Mycobacterium
tuberculosis str. Haarlem]
gi|134151611|gb|EBA43656.1| hypothetical 4-hydroxy-2-oxovalerate aldolase [Mycobacterium
tuberculosis str. Haarlem]
Length=346
Score = 695 bits (1794), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 345/346 (99%), Positives = 346/346 (100%), Gaps = 0/346 (0%)
Query 1 MTDMWDVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNY 60
MTDMWDVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNY
Sbjct 1 MTDMWDVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNY 60
Query 61 GFSKTPEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVS 120
GFSKTPEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVS
Sbjct 61 GFSKTPEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVS 120
Query 121 IQHFGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVAD 180
IQHFGLARELGLETVGFLMMAHTIAP+KLAAQARIMADAGCQCVYVVDSAGALVLDGVAD
Sbjct 121 IQHFGLARELGLETVGFLMMAHTIAPDKLAAQARIMADAGCQCVYVVDSAGALVLDGVAD 180
Query 181 RVSALVAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEAL 240
RVSALVAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEAL
Sbjct 181 RVSALVAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEAL 240
Query 241 IGVFDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQA 300
IGVFDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQA
Sbjct 241 IGVFDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQA 300
Query 301 ERYGVPASALLHRAGQRKLIGGQEDQLIDIALEIKRELDSGAAVTH 346
ERYGVPASALLHRAGQRKLIGGQEDQLIDIALEIKRELDSGAAVTH
Sbjct 301 ERYGVPASALLHRAGQRKLIGGQEDQLIDIALEIKRELDSGAAVTH 346
>gi|15843146|ref|NP_338183.1| 4-hydroxy-2-ketovalerate aldolase [Mycobacterium tuberculosis
CDC1551]
gi|308374911|ref|ZP_07667896.1| 4-hydroxy-2-oxovalerate aldolase [Mycobacterium tuberculosis
SUMu007]
gi|13883496|gb|AAK47997.1| 4-hydroxy-2-oxovalerate aldolase [Mycobacterium tuberculosis
CDC1551]
gi|308348050|gb|EFP36901.1| 4-hydroxy-2-oxovalerate aldolase [Mycobacterium tuberculosis
SUMu007]
Length=343
Score = 691 bits (1782), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 343/343 (100%), Positives = 343/343 (100%), Gaps = 0/343 (0%)
Query 4 MWDVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFS 63
MWDVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFS
Sbjct 1 MWDVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFS 60
Query 64 KTPEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVSIQH 123
KTPEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVSIQH
Sbjct 61 KTPEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVSIQH 120
Query 124 FGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVS 183
FGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVS
Sbjct 121 FGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVS 180
Query 184 ALVAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEALIGV 243
ALVAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEALIGV
Sbjct 181 ALVAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEALIGV 240
Query 244 FDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQAERY 303
FDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQAERY
Sbjct 241 FDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQAERY 300
Query 304 GVPASALLHRAGQRKLIGGQEDQLIDIALEIKRELDSGAAVTH 346
GVPASALLHRAGQRKLIGGQEDQLIDIALEIKRELDSGAAVTH
Sbjct 301 GVPASALLHRAGQRKLIGGQEDQLIDIALEIKRELDSGAAVTH 343
>gi|340628498|ref|YP_004746950.1| putative 4-hydroxy-2-oxovalerate aldolase [Mycobacterium canettii
CIPT 140010059]
gi|340006688|emb|CCC45876.1| putative 4-hydroxy-2-oxovalerate aldolase (HOA) [Mycobacterium
canettii CIPT 140010059]
Length=346
Score = 685 bits (1768), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 341/346 (99%), Positives = 342/346 (99%), Gaps = 0/346 (0%)
Query 1 MTDMWDVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNY 60
MTDM DVRITDTSLRDGSHHKRHQFTKDEV AIVAALDAAGVPVIEVTHGDGLGGSSFNY
Sbjct 1 MTDMRDVRITDTSLRDGSHHKRHQFTKDEVAAIVAALDAAGVPVIEVTHGDGLGGSSFNY 60
Query 61 GFSKTPEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVS 120
GFSKTPEQELIKLAA TA EARIAFLMLPGVGTKDDIKEA+DNGGSICRIATHCTEADVS
Sbjct 61 GFSKTPEQELIKLAAQTANEARIAFLMLPGVGTKDDIKEAQDNGGSICRIATHCTEADVS 120
Query 121 IQHFGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVAD 180
IQHFGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVAD
Sbjct 121 IQHFGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVAD 180
Query 181 RVSALVAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEAL 240
RVSALVAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEAL
Sbjct 181 RVSALVAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEAL 240
Query 241 IGVFDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQA 300
IGVFDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQA
Sbjct 241 IGVFDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQA 300
Query 301 ERYGVPASALLHRAGQRKLIGGQEDQLIDIALEIKRELDSGAAVTH 346
ERYGVPASALLHRAGQRKLIGGQEDQLIDIALEIKRELDSGAAVTH
Sbjct 301 ERYGVPASALLHRAGQRKLIGGQEDQLIDIALEIKRELDSGAAVTH 346
>gi|240172367|ref|ZP_04751026.1| 4-hydroxy-2-ketovalerate aldolase [Mycobacterium kansasii ATCC
12478]
Length=346
Score = 672 bits (1735), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 332/346 (96%), Positives = 339/346 (98%), Gaps = 0/346 (0%)
Query 1 MTDMWDVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNY 60
MT +WDVRITDTSLRDGSHHKRHQFTK+EVGAIVAALDAAGVPVIEVTHGDGLGGSSFNY
Sbjct 1 MTSIWDVRITDTSLRDGSHHKRHQFTKEEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNY 60
Query 61 GFSKTPEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVS 120
GFSKTPEQELIKLAA TAKEARIAFLMLPGVGTKDDIKEA+DNGGSICRIATHCTEADVS
Sbjct 61 GFSKTPEQELIKLAAETAKEARIAFLMLPGVGTKDDIKEAQDNGGSICRIATHCTEADVS 120
Query 121 IQHFGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVAD 180
IQHFGLARELGLETVGFLMMAHTI PEKLAAQARIMADAGCQCVYVVDSAGALVLDGVAD
Sbjct 121 IQHFGLARELGLETVGFLMMAHTIPPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVAD 180
Query 181 RVSALVAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEAL 240
RVSALVAELGEDAQVGFHGHENLGLGVANSV AVRAGAKQIDGS RRFGAGAGNAPVEAL
Sbjct 181 RVSALVAELGEDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSVRRFGAGAGNAPVEAL 240
Query 241 IGVFDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQA 300
IGVFDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQ+
Sbjct 241 IGVFDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQS 300
Query 301 ERYGVPASALLHRAGQRKLIGGQEDQLIDIALEIKRELDSGAAVTH 346
ERYGVPASALL+RAGQRKLIGGQEDQLIDIALEIKRE ++GA VTH
Sbjct 301 ERYGVPASALLYRAGQRKLIGGQEDQLIDIALEIKREQENGAVVTH 346
>gi|183984989|ref|YP_001853280.1| 4-hydroxy-2-oxovalerate aldolase [Mycobacterium marinum M]
gi|263430020|sp|B2HI25.1|HOA2_MYCMM RecName: Full=4-hydroxy-2-oxovalerate aldolase 2; Short=HOA 2;
AltName: Full=4-hydroxy-2-keto-pentanoic acid aldolase 2;
AltName: Full=4-hydroxy-2-oxopentanoate aldolase 2
gi|183178315|gb|ACC43425.1| 4-hydroxy-2-oxovalerate aldolase [Mycobacterium marinum M]
Length=347
Score = 659 bits (1701), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 325/341 (96%), Positives = 333/341 (98%), Gaps = 0/341 (0%)
Query 1 MTDMWDVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNY 60
MT +WDVRITDTSLRDGSHHKRHQF K+EVGAIVAALDAAGVPVIEVTHGDGLGGSSFNY
Sbjct 1 MTGIWDVRITDTSLRDGSHHKRHQFIKEEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNY 60
Query 61 GFSKTPEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVS 120
GFSKTPEQELIKLAA TAKEA+IAFLMLPGVGTK+DIKEA+DNGGSICRIATHCTEADVS
Sbjct 61 GFSKTPEQELIKLAAQTAKEAKIAFLMLPGVGTKEDIKEAQDNGGSICRIATHCTEADVS 120
Query 121 IQHFGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVAD 180
IQHFGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVAD
Sbjct 121 IQHFGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVAD 180
Query 181 RVSALVAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEAL 240
RV+ALVAELGEDAQVGFHGHENLGLGVANSV AVRAGAKQIDGS RRFGAGAGNAPVEAL
Sbjct 181 RVAALVAELGEDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSVRRFGAGAGNAPVEAL 240
Query 241 IGVFDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQA 300
IGVFDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQ+
Sbjct 241 IGVFDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQS 300
Query 301 ERYGVPASALLHRAGQRKLIGGQEDQLIDIALEIKRELDSG 341
ERYGVPA LLHRAGQRKLIGGQEDQLIDIALEIKRE +SG
Sbjct 301 ERYGVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQESG 341
>gi|118619280|ref|YP_907612.1| 4-hydroxy-2-ketovalerate aldolase [Mycobacterium ulcerans Agy99]
gi|263430044|sp|A0PUX2.1|HOA2_MYCUA RecName: Full=4-hydroxy-2-oxovalerate aldolase 2; Short=HOA 2;
AltName: Full=4-hydroxy-2-keto-pentanoic acid aldolase 2;
AltName: Full=4-hydroxy-2-oxopentanoate aldolase 2
gi|118571390|gb|ABL06141.1| 4-hydroxy-2-oxovalerate aldolase [Mycobacterium ulcerans Agy99]
Length=347
Score = 654 bits (1687), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 323/341 (95%), Positives = 331/341 (98%), Gaps = 0/341 (0%)
Query 1 MTDMWDVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNY 60
MT +WDVRITDTSLRDGSHHKRHQF K+EVGAIVAALDAAGVPVIEVTHGDGLGGSSFNY
Sbjct 1 MTGIWDVRITDTSLRDGSHHKRHQFIKEEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNY 60
Query 61 GFSKTPEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVS 120
GFSKT EQELIKLAA TAKEA+IAFLMLPGVGTK+DIKEA+DNGGSICRIATHCTEADVS
Sbjct 61 GFSKTSEQELIKLAAQTAKEAKIAFLMLPGVGTKEDIKEAQDNGGSICRIATHCTEADVS 120
Query 121 IQHFGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVAD 180
IQH GLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVAD
Sbjct 121 IQHLGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVAD 180
Query 181 RVSALVAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEAL 240
RV+ALVAELGEDAQVGFHGHENLGLGVANSV AVRAGAKQIDGS RRFGAGAGNAPVEAL
Sbjct 181 RVAALVAELGEDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSVRRFGAGAGNAPVEAL 240
Query 241 IGVFDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQA 300
IGVFDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQ+
Sbjct 241 IGVFDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQS 300
Query 301 ERYGVPASALLHRAGQRKLIGGQEDQLIDIALEIKRELDSG 341
ERYGVPA LLHRAGQRKLIGGQEDQLIDIALEIKRE +SG
Sbjct 301 ERYGVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQESG 341
>gi|296166563|ref|ZP_06848993.1| 4-hydroxy-2-oxovalerate aldolase [Mycobacterium parascrofulaceum
ATCC BAA-614]
gi|295898049|gb|EFG77625.1| 4-hydroxy-2-oxovalerate aldolase [Mycobacterium parascrofulaceum
ATCC BAA-614]
Length=353
Score = 652 bits (1681), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 318/344 (93%), Positives = 334/344 (98%), Gaps = 0/344 (0%)
Query 1 MTDMWDVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNY 60
+WDVR+TDTSLRDGSHHKRHQFTKDEVGAIVAALD AGVPVIEVTHGDGLGGSSFNY
Sbjct 8 FNPIWDVRLTDTSLRDGSHHKRHQFTKDEVGAIVAALDTAGVPVIEVTHGDGLGGSSFNY 67
Query 61 GFSKTPEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVS 120
GFS+TPEQELIKLAAATAKEA+IAFLMLPGVGTK+DIKEA++NGGSICRIATHCTEADVS
Sbjct 68 GFSRTPEQELIKLAAATAKEAKIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCTEADVS 127
Query 121 IQHFGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVAD 180
IQHFGLARELGLETVGFLMM+HTIAPEKLAAQARIMADAGCQCVYVVDSAGALVL+GV D
Sbjct 128 IQHFGLARELGLETVGFLMMSHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLEGVRD 187
Query 181 RVSALVAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEAL 240
RV+ALVAELG+DAQVGFHGHENLGLGVANSV AVRAGAKQIDGSCRRFGAGAGNAPVEAL
Sbjct 188 RVAALVAELGDDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNAPVEAL 247
Query 241 IGVFDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQA 300
IGVFDKIGVKTGIDFFDIADAAE+VV PAMPAECLLDRNALIMGYSGVYSSFLKHA+RQ+
Sbjct 248 IGVFDKIGVKTGIDFFDIADAAEEVVAPAMPAECLLDRNALIMGYSGVYSSFLKHAIRQS 307
Query 301 ERYGVPASALLHRAGQRKLIGGQEDQLIDIALEIKRELDSGAAV 344
ERYGVPA LLHRAGQRKLIGGQEDQLIDIALEIKRE +SG+AV
Sbjct 308 ERYGVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQESGSAV 351
>gi|108801622|ref|YP_641819.1| 4-hydroxy-2-ketovalerate aldolase [Mycobacterium sp. MCS]
gi|119870776|ref|YP_940728.1| 4-hydroxy-2-ketovalerate aldolase [Mycobacterium sp. KMS]
gi|123368687|sp|Q1B2X1.1|HOA1_MYCSS RecName: Full=4-hydroxy-2-oxovalerate aldolase 1; Short=HOA 1;
AltName: Full=4-hydroxy-2-keto-pentanoic acid aldolase 1;
AltName: Full=4-hydroxy-2-oxopentanoate aldolase 1
gi|263429873|sp|A1UM80.1|HOA1_MYCSK RecName: Full=4-hydroxy-2-oxovalerate aldolase 1; Short=HOA 1;
AltName: Full=4-hydroxy-2-keto-pentanoic acid aldolase 1;
AltName: Full=4-hydroxy-2-oxopentanoate aldolase 1
gi|108772041|gb|ABG10763.1| pyruvate carboxyltransferase [Mycobacterium sp. MCS]
gi|119696865|gb|ABL93938.1| pyruvate carboxyltransferase [Mycobacterium sp. KMS]
Length=353
Score = 649 bits (1674), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 317/343 (93%), Positives = 330/343 (97%), Gaps = 0/343 (0%)
Query 4 MWDVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFS 63
+WDVR+TDTSLRDGSHHKRHQFTKDEVGAIVAALD AGVPVIEVTHGDGLGGSSFNYGFS
Sbjct 11 IWDVRMTDTSLRDGSHHKRHQFTKDEVGAIVAALDTAGVPVIEVTHGDGLGGSSFNYGFS 70
Query 64 KTPEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVSIQH 123
KTPEQELIKLAA TAKEA+IAFLMLPGVGTK+DIKEA++NGGSICRIATHCTEADVSIQH
Sbjct 71 KTPEQELIKLAAETAKEAKIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCTEADVSIQH 130
Query 124 FGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVS 183
FGLARELGLETVGFLMM+HTI PEKLA QARIMADAGCQCVYVVDSAGALVL+GV DRV+
Sbjct 131 FGLARELGLETVGFLMMSHTIPPEKLAQQARIMADAGCQCVYVVDSAGALVLEGVRDRVA 190
Query 184 ALVAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEALIGV 243
ALVAELG+DAQVGFHGHENLGLGVANSV AVRAGAKQIDGSCRRFGAGAGNAPVEALIGV
Sbjct 191 ALVAELGDDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNAPVEALIGV 250
Query 244 FDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQAERY 303
FDKIGVKTGIDFFDIADAAE+VV PAMPAECLLDRNALIMGYSGVYSSFLKHA+RQ+ERY
Sbjct 251 FDKIGVKTGIDFFDIADAAEEVVAPAMPAECLLDRNALIMGYSGVYSSFLKHAIRQSERY 310
Query 304 GVPASALLHRAGQRKLIGGQEDQLIDIALEIKRELDSGAAVTH 346
GVPA LLHRAGQRKLIGGQEDQLIDIALEIKRE DSGA H
Sbjct 311 GVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQDSGATAAH 353
>gi|126437606|ref|YP_001073297.1| 4-hydroxy-2-ketovalerate aldolase [Mycobacterium sp. JLS]
gi|263430026|sp|A3Q6M9.1|HOA2_MYCSJ RecName: Full=4-hydroxy-2-oxovalerate aldolase 2; Short=HOA 2;
AltName: Full=4-hydroxy-2-keto-pentanoic acid aldolase 2;
AltName: Full=4-hydroxy-2-oxopentanoate aldolase 2
gi|126237406|gb|ABO00807.1| pyruvate carboxyltransferase [Mycobacterium sp. JLS]
Length=353
Score = 649 bits (1673), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 317/343 (93%), Positives = 329/343 (96%), Gaps = 0/343 (0%)
Query 4 MWDVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFS 63
+WDVR+TDTSLRDGSHHKRHQFTKDEVGAIVAALD AGVPVIEVTHGDGLGGSSFNYGFS
Sbjct 11 IWDVRMTDTSLRDGSHHKRHQFTKDEVGAIVAALDTAGVPVIEVTHGDGLGGSSFNYGFS 70
Query 64 KTPEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVSIQH 123
KTPEQELIKLAA TAKEA+IAFLMLPGVGTK+DIKEA++NGGSICRIATHCTEADVSIQH
Sbjct 71 KTPEQELIKLAAETAKEAKIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCTEADVSIQH 130
Query 124 FGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVS 183
FGLARELGLETVGFLMM+HTI PEKLA QARIMADAGCQCVYVVDSAGALVL+GV DRV+
Sbjct 131 FGLARELGLETVGFLMMSHTIPPEKLAQQARIMADAGCQCVYVVDSAGALVLEGVRDRVA 190
Query 184 ALVAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEALIGV 243
ALVAELG DAQVGFHGHENLGLGVANSV AVRAGAKQIDGSCRRFGAGAGNAPVEALIGV
Sbjct 191 ALVAELGSDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNAPVEALIGV 250
Query 244 FDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQAERY 303
FDKIGVKTGIDFFDIADAAE+VV PAMPAECLLDRNALIMGYSGVYSSFLKHA+RQ+ERY
Sbjct 251 FDKIGVKTGIDFFDIADAAEEVVAPAMPAECLLDRNALIMGYSGVYSSFLKHAIRQSERY 310
Query 304 GVPASALLHRAGQRKLIGGQEDQLIDIALEIKRELDSGAAVTH 346
GVPA LLHRAGQRKLIGGQEDQLIDIALEIKRE DSGA H
Sbjct 311 GVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQDSGATAAH 353
>gi|118462327|ref|YP_879907.1| 4-hydroxy-2-ketovalerate aldolase [Mycobacterium avium 104]
gi|254773584|ref|ZP_05215100.1| 4-hydroxy-2-ketovalerate aldolase [Mycobacterium avium subsp.
avium ATCC 25291]
gi|263430393|sp|A0QAG9.1|HOA_MYCA1 RecName: Full=4-hydroxy-2-oxovalerate aldolase; Short=HOA; AltName:
Full=4-hydroxy-2-keto-pentanoic acid aldolase; AltName:
Full=4-hydroxy-2-oxopentanoate aldolase
gi|118163614|gb|ABK64511.1| 4-hydroxy-2-oxovalerate aldolase [Mycobacterium avium 104]
Length=352
Score = 645 bits (1664), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 316/340 (93%), Positives = 329/340 (97%), Gaps = 0/340 (0%)
Query 4 MWDVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFS 63
MWDVR+TDTSLRDGSHHKRHQFTKDEV AIVAALD AGVPVIEVTHGDGLGGSSFNYGFS
Sbjct 10 MWDVRLTDTSLRDGSHHKRHQFTKDEVQAIVAALDVAGVPVIEVTHGDGLGGSSFNYGFS 69
Query 64 KTPEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVSIQH 123
KTPEQELIKLAA TAKEA+IAFLMLPGVGTK+DIKEA++NGGSICRIATHCTEADVSIQH
Sbjct 70 KTPEQELIKLAAETAKEAKIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCTEADVSIQH 129
Query 124 FGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVS 183
FGLARELGLETVGFLMM+HTI PEKLA QARIMADAGCQCVYVVDSAGALVL+GV DRV+
Sbjct 130 FGLARELGLETVGFLMMSHTIPPEKLAQQARIMADAGCQCVYVVDSAGALVLEGVRDRVA 189
Query 184 ALVAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEALIGV 243
ALVAELG+DAQVGFHGHENLGLGVANSV AVRAGAKQIDGSCRRFGAGAGNAPVEALIGV
Sbjct 190 ALVAELGDDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNAPVEALIGV 249
Query 244 FDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQAERY 303
FDKIGVKTGIDFFDIADAAE+VV PAMPAECLLDRNALIMGYSGVYSSFLKHA+RQ+ERY
Sbjct 250 FDKIGVKTGIDFFDIADAAEEVVAPAMPAECLLDRNALIMGYSGVYSSFLKHAIRQSERY 309
Query 304 GVPASALLHRAGQRKLIGGQEDQLIDIALEIKRELDSGAA 343
GVPA LLHRAGQRKLIGGQEDQLIDIALEIKRE +SGAA
Sbjct 310 GVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQESGAA 349
>gi|254822616|ref|ZP_05227617.1| 4-hydroxy-2-ketovalerate aldolase [Mycobacterium intracellulare
ATCC 13950]
Length=352
Score = 645 bits (1663), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 316/343 (93%), Positives = 330/343 (97%), Gaps = 0/343 (0%)
Query 1 MTDMWDVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNY 60
+WDVR+TDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNY
Sbjct 7 FNPVWDVRMTDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNY 66
Query 61 GFSKTPEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVS 120
GFSKTPEQELIKLAA TAKEA+IAFLMLPGVGTK+DIKEA++NGG ICRIATHCTEADVS
Sbjct 67 GFSKTPEQELIKLAAETAKEAKIAFLMLPGVGTKEDIKEAQNNGGEICRIATHCTEADVS 126
Query 121 IQHFGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVAD 180
IQHFGLARELGLETVGFLMM+HTI+PEKLAAQARIMADAGCQCVYVVDSAGALVL+GV D
Sbjct 127 IQHFGLARELGLETVGFLMMSHTISPEKLAAQARIMADAGCQCVYVVDSAGALVLEGVRD 186
Query 181 RVSALVAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEAL 240
RV+ALVAELG+DAQVGFHGHENLGLGVANSV AVRAGAKQIDGSCRRFGAGAGNAPVEAL
Sbjct 187 RVAALVAELGDDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNAPVEAL 246
Query 241 IGVFDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQA 300
IGVFDKIGVKTGIDFFDIADAAE+VV PAMPAECLLDRNALIMGYSGVYSSFLKHA+RQ
Sbjct 247 IGVFDKIGVKTGIDFFDIADAAEEVVAPAMPAECLLDRNALIMGYSGVYSSFLKHAIRQG 306
Query 301 ERYGVPASALLHRAGQRKLIGGQEDQLIDIALEIKRELDSGAA 343
ERYGVP LLHRAGQRKLIGGQEDQLIDIALEIKRE +SGAA
Sbjct 307 ERYGVPPHELLHRAGQRKLIGGQEDQLIDIALEIKRERESGAA 349
>gi|145222114|ref|YP_001132792.1| 4-hydroxy-2-ketovalerate aldolase [Mycobacterium gilvum PYR-GCK]
gi|315442554|ref|YP_004075433.1| 4-hydroxy-2-oxovalerate aldolase [Mycobacterium sp. Spyr1]
gi|263430414|sp|A4T7U4.1|HOA_MYCGI RecName: Full=4-hydroxy-2-oxovalerate aldolase; Short=HOA; AltName:
Full=4-hydroxy-2-keto-pentanoic acid aldolase; AltName:
Full=4-hydroxy-2-oxopentanoate aldolase
gi|145214600|gb|ABP44004.1| pyruvate carboxyltransferase [Mycobacterium gilvum PYR-GCK]
gi|315260857|gb|ADT97598.1| 4-hydroxy-2-oxovalerate aldolase [Mycobacterium sp. Spyr1]
Length=352
Score = 645 bits (1663), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 313/339 (93%), Positives = 331/339 (98%), Gaps = 0/339 (0%)
Query 4 MWDVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFS 63
+WDVR+TDTSLRDGSHHKRHQFTKDEVG+IVAALDAAGVPVIEVTHGDGLGGSSFNYGFS
Sbjct 11 IWDVRMTDTSLRDGSHHKRHQFTKDEVGSIVAALDAAGVPVIEVTHGDGLGGSSFNYGFS 70
Query 64 KTPEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVSIQH 123
KTPEQELIKLAA TAKE++IAFLMLPGVGTK+DIKEA++NGGSICRIATHCTEADVSIQH
Sbjct 71 KTPEQELIKLAAETAKESKIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCTEADVSIQH 130
Query 124 FGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVS 183
FGLARELGLETVGFLMM+HTI+PEKLA QARIMADAGCQCVYVVDSAGALVL+GVADRVS
Sbjct 131 FGLARELGLETVGFLMMSHTISPEKLAKQARIMADAGCQCVYVVDSAGALVLEGVADRVS 190
Query 184 ALVAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEALIGV 243
ALVAELG+DAQVGFHGHENLGLGVANS+ AVRAGAKQIDGSCRRFGAGAGNAPVEALIGV
Sbjct 191 ALVAELGDDAQVGFHGHENLGLGVANSIEAVRAGAKQIDGSCRRFGAGAGNAPVEALIGV 250
Query 244 FDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQAERY 303
FDKIGVKTGIDFFDIADAAE+VV PAMPAECLLDRNALIMGYSGVYSSFLKHA+RQ+ERY
Sbjct 251 FDKIGVKTGIDFFDIADAAEEVVAPAMPAECLLDRNALIMGYSGVYSSFLKHAIRQSERY 310
Query 304 GVPASALLHRAGQRKLIGGQEDQLIDIALEIKRELDSGA 342
GVPA LLHRAGQRKLIGGQEDQLIDIALEIKRE ++ A
Sbjct 311 GVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQEAEA 349
>gi|126436796|ref|YP_001072487.1| 4-hydroxy-2-ketovalerate aldolase [Mycobacterium sp. JLS]
gi|263429870|sp|A3Q4B9.1|HOA1_MYCSJ RecName: Full=4-hydroxy-2-oxovalerate aldolase 1; Short=HOA 1;
AltName: Full=4-hydroxy-2-keto-pentanoic acid aldolase 1;
AltName: Full=4-hydroxy-2-oxopentanoate aldolase 1
gi|126236596|gb|ABN99996.1| 4-hydroxy-2-oxovalerate aldolase [Mycobacterium sp. JLS]
Length=363
Score = 645 bits (1663), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 315/340 (93%), Positives = 330/340 (98%), Gaps = 0/340 (0%)
Query 4 MWDVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFS 63
+WDVR+TDTSLRDGSHHKRHQFTKDEVGAIVAALD AGVPVIEVTHGDGLGGSSFNYGFS
Sbjct 10 IWDVRMTDTSLRDGSHHKRHQFTKDEVGAIVAALDTAGVPVIEVTHGDGLGGSSFNYGFS 69
Query 64 KTPEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVSIQH 123
KTPEQELIKLAA TAKEA+IAFLMLPGVGTK+DIKEA++NGGSICRIATHCTEADVSIQH
Sbjct 70 KTPEQELIKLAAETAKEAKIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCTEADVSIQH 129
Query 124 FGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVS 183
FGLARELGLETVGFLMM+HTI PEKLA QARIMADAGCQCVYVVDSAGALVL+GV DRV+
Sbjct 130 FGLARELGLETVGFLMMSHTIPPEKLAQQARIMADAGCQCVYVVDSAGALVLEGVRDRVA 189
Query 184 ALVAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEALIGV 243
ALVAELG+DAQVGFHGHENLGLGVANSV AVRAGAKQIDGSCRRFGAGAGNAPVEALIGV
Sbjct 190 ALVAELGDDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNAPVEALIGV 249
Query 244 FDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQAERY 303
FDKIGVKTGIDFFDIADAAE+VV PAMPAECLLDRNALIMGYSGVYSSFLKHA+RQ+ERY
Sbjct 250 FDKIGVKTGIDFFDIADAAEEVVAPAMPAECLLDRNALIMGYSGVYSSFLKHAIRQSERY 309
Query 304 GVPASALLHRAGQRKLIGGQEDQLIDIALEIKRELDSGAA 343
GVPA LLHRAGQRKLIGGQEDQLIDIALEIKRE++S AA
Sbjct 310 GVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREMESDAA 349
>gi|41406631|ref|NP_959467.1| 4-hydroxy-2-ketovalerate aldolase [Mycobacterium avium subsp.
paratuberculosis K-10]
gi|81414865|sp|Q743Q8.1|HOA_MYCPA RecName: Full=4-hydroxy-2-oxovalerate aldolase; Short=HOA; AltName:
Full=4-hydroxy-2-keto-pentanoic acid aldolase; AltName:
Full=4-hydroxy-2-oxopentanoate aldolase
gi|41394980|gb|AAS02850.1| hypothetical protein MAP_0533 [Mycobacterium avium subsp. paratuberculosis
K-10]
gi|336458421|gb|EGO37395.1| 4-hydroxy-2-oxovalerate aldolase [Mycobacterium avium subsp.
paratuberculosis S397]
Length=352
Score = 643 bits (1659), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 315/340 (93%), Positives = 330/340 (98%), Gaps = 0/340 (0%)
Query 4 MWDVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFS 63
+WDVR+TDTSLRDGSHHKRHQFTKDEV AIVAALDAAGVPVIEVTHGDGLGGSSFNYGFS
Sbjct 10 IWDVRLTDTSLRDGSHHKRHQFTKDEVQAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFS 69
Query 64 KTPEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVSIQH 123
KTPEQELIKLAA TAK+A+IAFLMLPGVGTK+DIKEA++NGGSICRIATHCTEADVSIQH
Sbjct 70 KTPEQELIKLAAETAKDAKIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCTEADVSIQH 129
Query 124 FGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVS 183
FGLARELGLETVGFLMM+HTI PEKLA QARIMADAGCQCVYVVDSAGALVL+GV DRV+
Sbjct 130 FGLARELGLETVGFLMMSHTIPPEKLAQQARIMADAGCQCVYVVDSAGALVLEGVRDRVA 189
Query 184 ALVAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEALIGV 243
ALVAELG+DAQVGFHGHENLGLGVANSV AVRAGAKQIDGSCRRFGAGAGNAPVEALIGV
Sbjct 190 ALVAELGDDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNAPVEALIGV 249
Query 244 FDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQAERY 303
FDKIGVKTGIDFFDIADAAE+VV PAMPAECLLDRNALIMGYSGVYSSFLKHA+RQ+ERY
Sbjct 250 FDKIGVKTGIDFFDIADAAEEVVAPAMPAECLLDRNALIMGYSGVYSSFLKHAIRQSERY 309
Query 304 GVPASALLHRAGQRKLIGGQEDQLIDIALEIKRELDSGAA 343
GVPA LLHRAGQRKLIGGQEDQLIDIALEIKRE +SGAA
Sbjct 310 GVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQESGAA 349
>gi|342862266|ref|ZP_08718908.1| 4-hyroxy-2-oxovalerate/4-hydroxy-2-oxopentanoic acid aldolase
[Mycobacterium colombiense CECT 3035]
gi|342130344|gb|EGT83664.1| 4-hyroxy-2-oxovalerate/4-hydroxy-2-oxopentanoic acid aldolase
[Mycobacterium colombiense CECT 3035]
Length=353
Score = 643 bits (1659), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 313/343 (92%), Positives = 330/343 (97%), Gaps = 0/343 (0%)
Query 4 MWDVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFS 63
+WD+R+TDTSLRDGSHHKRHQFTKDEVGAIVAALD AGVPVIEVTHGDGLGGSSFNYGFS
Sbjct 11 VWDIRLTDTSLRDGSHHKRHQFTKDEVGAIVAALDTAGVPVIEVTHGDGLGGSSFNYGFS 70
Query 64 KTPEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVSIQH 123
KTPEQELIKLAA TAK A+IAFLMLPGVGTK+DIKEA++NGG ICRIATHCTEADVSIQH
Sbjct 71 KTPEQELIKLAAQTAKAAKIAFLMLPGVGTKEDIKEAQNNGGEICRIATHCTEADVSIQH 130
Query 124 FGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVS 183
FGLARELGLETVGFLMM+HTI+PEKLAAQARIMADAGCQCVYVVDSAGALVL+GV DRV+
Sbjct 131 FGLARELGLETVGFLMMSHTISPEKLAAQARIMADAGCQCVYVVDSAGALVLEGVRDRVA 190
Query 184 ALVAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEALIGV 243
ALVAELG+DAQVGFHGHENLGLGVANSV AVRAGAKQIDGSCRRFGAGAGNAPVEALIGV
Sbjct 191 ALVAELGDDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNAPVEALIGV 250
Query 244 FDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQAERY 303
FDKIGVKTGIDFFDIADAAE+VV PAMPAECLLDRNALIMGYSGVYSSFLKHA+RQ+ERY
Sbjct 251 FDKIGVKTGIDFFDIADAAEEVVAPAMPAECLLDRNALIMGYSGVYSSFLKHAIRQSERY 310
Query 304 GVPASALLHRAGQRKLIGGQEDQLIDIALEIKRELDSGAAVTH 346
GVPA LLHRAGQRKLIGGQEDQLIDIALEIKRE ++GA H
Sbjct 311 GVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQENGATAPH 353
>gi|342860635|ref|ZP_08717285.1| 4-hyroxy-2-oxovalerate/4-hydroxy-2-oxopentanoic acid aldolase
[Mycobacterium colombiense CECT 3035]
gi|342131659|gb|EGT84916.1| 4-hyroxy-2-oxovalerate/4-hydroxy-2-oxopentanoic acid aldolase
[Mycobacterium colombiense CECT 3035]
Length=353
Score = 641 bits (1654), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 312/343 (91%), Positives = 329/343 (96%), Gaps = 0/343 (0%)
Query 4 MWDVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFS 63
+WD+R+TDTSLRDGSHHKRHQFTKDEVGAIVAALD AGVPVIEVTHGDGLGGSSFNYGFS
Sbjct 11 VWDIRLTDTSLRDGSHHKRHQFTKDEVGAIVAALDTAGVPVIEVTHGDGLGGSSFNYGFS 70
Query 64 KTPEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVSIQH 123
KTPEQELIKLAA TA A+IAFLMLPGVGTK+DIKEA++NGG ICRIATHCTEADVSIQH
Sbjct 71 KTPEQELIKLAAQTATAAKIAFLMLPGVGTKEDIKEAQNNGGEICRIATHCTEADVSIQH 130
Query 124 FGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVS 183
FGLARELGLETVGFLMM+HTI+PEKLAAQARIMADAGCQCVYVVDSAGALVL+GV DRV+
Sbjct 131 FGLARELGLETVGFLMMSHTISPEKLAAQARIMADAGCQCVYVVDSAGALVLEGVRDRVA 190
Query 184 ALVAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEALIGV 243
ALVAELG+DAQVGFHGHENLGLGVANSV AVRAGAKQIDGSCRRFGAGAGNAPVEALIGV
Sbjct 191 ALVAELGDDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNAPVEALIGV 250
Query 244 FDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQAERY 303
FDKIGVKTGIDFFDIADAAE+VV PAMPAECLLDRNALIMGYSGVYSSFLKHA+RQ+ERY
Sbjct 251 FDKIGVKTGIDFFDIADAAEEVVAPAMPAECLLDRNALIMGYSGVYSSFLKHAIRQSERY 310
Query 304 GVPASALLHRAGQRKLIGGQEDQLIDIALEIKRELDSGAAVTH 346
GVPA LLHRAGQRKLIGGQEDQLIDIALEIKRE ++GA H
Sbjct 311 GVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQENGATAPH 353
>gi|254820084|ref|ZP_05225085.1| 4-hydroxy-2-ketovalerate aldolase [Mycobacterium intracellulare
ATCC 13950]
Length=359
Score = 641 bits (1653), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 315/342 (93%), Positives = 329/342 (97%), Gaps = 0/342 (0%)
Query 4 MWDVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFS 63
+WDVR+TDTSLRDGSHHKRHQFT DEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFS
Sbjct 10 IWDVRMTDTSLRDGSHHKRHQFTTDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFS 69
Query 64 KTPEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVSIQH 123
KTPEQELIKLAA TAKEA+IAFLMLPGVGTK+DIKEA++NGG ICRIATHCTEADVSIQH
Sbjct 70 KTPEQELIKLAADTAKEAKIAFLMLPGVGTKEDIKEAQNNGGEICRIATHCTEADVSIQH 129
Query 124 FGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVS 183
FGLARELGLETVGFLMM+HTI PEKLAAQARIMADAGCQCVYVVDSAGALVL+GV DRV+
Sbjct 130 FGLARELGLETVGFLMMSHTITPEKLAAQARIMADAGCQCVYVVDSAGALVLEGVRDRVA 189
Query 184 ALVAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEALIGV 243
ALVAELG+DAQVGFHGHENLGLGVANSV AVRAGAKQIDGSCRRFGAGAGNAPVEALIGV
Sbjct 190 ALVAELGDDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNAPVEALIGV 249
Query 244 FDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQAERY 303
FDKIGVKTGIDFFDIADAAE+VV PAMPAECLLDRNALIMGYSGVYSSFLKHA+RQ+ERY
Sbjct 250 FDKIGVKTGIDFFDIADAAEEVVAPAMPAECLLDRNALIMGYSGVYSSFLKHAIRQSERY 309
Query 304 GVPASALLHRAGQRKLIGGQEDQLIDIALEIKRELDSGAAVT 345
GVPA LLHRAGQRKLIGGQEDQLIDIALEIKRE + AVT
Sbjct 310 GVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREHHTVKAVT 351
>gi|120406182|ref|YP_956011.1| 4-hydroxy-2-ketovalerate aldolase [Mycobacterium vanbaalenii
PYR-1]
gi|263430129|sp|A1TFQ5.1|HOA3_MYCVP RecName: Full=4-hydroxy-2-oxovalerate aldolase 3; Short=HOA 3;
AltName: Full=4-hydroxy-2-keto-pentanoic acid aldolase 3;
AltName: Full=4-hydroxy-2-oxopentanoate aldolase 3
gi|119959000|gb|ABM16005.1| pyruvate carboxyltransferase [Mycobacterium vanbaalenii PYR-1]
Length=350
Score = 640 bits (1651), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 311/337 (93%), Positives = 326/337 (97%), Gaps = 0/337 (0%)
Query 4 MWDVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFS 63
+WDVR+TDTSLRDGSHHKRHQFTKDEV AIVAALDAAGVPVIEVTHGDGLGGSSFNYGFS
Sbjct 11 IWDVRMTDTSLRDGSHHKRHQFTKDEVQAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFS 70
Query 64 KTPEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVSIQH 123
KTPEQELIKLAA TAKE++IAFLMLPGVGTK+DIKEA+ NGGSICRIATHCTEADVSIQH
Sbjct 71 KTPEQELIKLAAETAKESKIAFLMLPGVGTKEDIKEAQSNGGSICRIATHCTEADVSIQH 130
Query 124 FGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVS 183
FGLARELGLETVGFLMM+HTI PEKLA QARIMADAGCQCVYVVDSAGALVL+GVADRV+
Sbjct 131 FGLARELGLETVGFLMMSHTIPPEKLAKQARIMADAGCQCVYVVDSAGALVLEGVADRVA 190
Query 184 ALVAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEALIGV 243
ALVAELG DAQVGFHGHENLGLGVANS+ AVRAGAKQIDGSCRRFGAGAGNAPVEALIGV
Sbjct 191 ALVAELGSDAQVGFHGHENLGLGVANSIEAVRAGAKQIDGSCRRFGAGAGNAPVEALIGV 250
Query 244 FDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQAERY 303
FDKIGVKTGIDFFDIADAAE+VV PAMPAECLLDRNALIMGYSGVYSSFLKHA+RQ+ERY
Sbjct 251 FDKIGVKTGIDFFDIADAAEEVVAPAMPAECLLDRNALIMGYSGVYSSFLKHAIRQSERY 310
Query 304 GVPASALLHRAGQRKLIGGQEDQLIDIALEIKRELDS 340
GVPA LLHRAGQRKLIGGQEDQLIDIALEIKRE ++
Sbjct 311 GVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQET 347
>gi|118469867|ref|YP_890164.1| 4-hydroxy-2-ketovalerate aldolase [Mycobacterium smegmatis str.
MC2 155]
gi|263430023|sp|A0R4S6.1|HOA2_MYCS2 RecName: Full=4-hydroxy-2-oxovalerate aldolase 2; Short=HOA 2;
AltName: Full=4-hydroxy-2-keto-pentanoic acid aldolase 2;
AltName: Full=4-hydroxy-2-oxopentanoate aldolase 2
gi|118171154|gb|ABK72050.1| 4-hydroxy-2-oxovalerate aldolase [Mycobacterium smegmatis str.
MC2 155]
Length=349
Score = 635 bits (1637), Expect = 4e-180, Method: Compositional matrix adjust.
Identities = 309/343 (91%), Positives = 327/343 (96%), Gaps = 0/343 (0%)
Query 1 MTDMWDVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNY 60
+WDVR+TDTSLRDGSHHKRHQFT +EV +IVAALDAAGVPVIEVTHGDGLGGSSFNY
Sbjct 6 FNPIWDVRMTDTSLRDGSHHKRHQFTGEEVRSIVAALDAAGVPVIEVTHGDGLGGSSFNY 65
Query 61 GFSKTPEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVS 120
GFSKTPEQELIK+AA TAKE++IAFLMLPGVGTK+DIKEA++NGGSICRIATHCTEADVS
Sbjct 66 GFSKTPEQELIKIAAETAKESKIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCTEADVS 125
Query 121 IQHFGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVAD 180
IQHFGLARELGLETVGFLMMAHTI+PEKLA QARIMADAGCQCVYVVDSAGALVL+GV D
Sbjct 126 IQHFGLARELGLETVGFLMMAHTISPEKLAQQARIMADAGCQCVYVVDSAGALVLEGVRD 185
Query 181 RVSALVAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEAL 240
RV ALVAELG DAQVGFHGHENLGLGVANSV AVRAGAKQIDGSCRRFGAGAGNAPVEAL
Sbjct 186 RVQALVAELGSDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNAPVEAL 245
Query 241 IGVFDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQA 300
IGVFDKIGVKTGIDFFDIADAAE+VV PAMPAECLLDRNALIMGYSGVYSSFLKHA+RQ+
Sbjct 246 IGVFDKIGVKTGIDFFDIADAAEEVVAPAMPAECLLDRNALIMGYSGVYSSFLKHAIRQS 305
Query 301 ERYGVPASALLHRAGQRKLIGGQEDQLIDIALEIKRELDSGAA 343
ERYGVPA LLHRAGQRKLIGGQEDQLIDIALEIKRE ++ A+
Sbjct 306 ERYGVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQEAAAS 348
>gi|169627729|ref|YP_001701378.1| 4-hydroxy-2-ketovalerate aldolase [Mycobacterium abscessus ATCC
19977]
gi|263429846|sp|B1MH40.1|HOA1_MYCA9 RecName: Full=4-hydroxy-2-oxovalerate aldolase 1; Short=HOA 1;
AltName: Full=4-hydroxy-2-keto-pentanoic acid aldolase 1;
AltName: Full=4-hydroxy-2-oxopentanoate aldolase 1
gi|169239696|emb|CAM60724.1| Probable 4-hydroxy-2-oxovalerate aldolase (Hoa) / pyruvate carboxyltransferase
[Mycobacterium abscessus]
Length=359
Score = 602 bits (1551), Expect = 4e-170, Method: Compositional matrix adjust.
Identities = 303/333 (91%), Positives = 316/333 (95%), Gaps = 0/333 (0%)
Query 5 WDVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFSK 64
WDVR+TDTSLRDGSHHKRHQFT DEV AIVAALD AGVPVIEVTHGDGLGGSSFNYGFSK
Sbjct 21 WDVRVTDTSLRDGSHHKRHQFTADEVRAIVAALDGAGVPVIEVTHGDGLGGSSFNYGFSK 80
Query 65 TPEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVSIQHF 124
TPEQELIKLAA TA A+IAFLMLPGVGTK+DI EA+ NGGSICRIATHCTEADVSIQHF
Sbjct 81 TPEQELIKLAAQTATNAKIAFLMLPGVGTKEDIIEAQGNGGSICRIATHCTEADVSIQHF 140
Query 125 GLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVSA 184
GLARE GLETVGFLMM+HTI+PEKLA QARIMADAGCQCVYVVDSAGALVLDGVADRV+A
Sbjct 141 GLARERGLETVGFLMMSHTISPEKLAKQARIMADAGCQCVYVVDSAGALVLDGVADRVAA 200
Query 185 LVAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEALIGVF 244
+VAELG DAQVGFHGHENLGLGVANS+ AVRAGAKQIDGS RRFGAGAGNAPVEALIGVF
Sbjct 201 VVAELGSDAQVGFHGHENLGLGVANSIEAVRAGAKQIDGSTRRFGAGAGNAPVEALIGVF 260
Query 245 DKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQAERYG 304
DKIGVKTGIDFFDIADAAE+VV PAMPAECLLDRNALIMGYSGVYSSFLKHA+RQ ERYG
Sbjct 261 DKIGVKTGIDFFDIADAAEEVVAPAMPAECLLDRNALIMGYSGVYSSFLKHAIRQGERYG 320
Query 305 VPASALLHRAGQRKLIGGQEDQLIDIALEIKRE 337
VPA LLHRAG+RKLIGGQEDQLIDIALEI+RE
Sbjct 321 VPAHQLLHRAGERKLIGGQEDQLIDIALEIQRE 353
>gi|333992319|ref|YP_004524933.1| 4-hydroxy-2-oxovalerate aldolase [Mycobacterium sp. JDM601]
gi|333488287|gb|AEF37679.1| 4-hydroxy-2-oxovalerate aldolase [Mycobacterium sp. JDM601]
Length=344
Score = 597 bits (1538), Expect = 1e-168, Method: Compositional matrix adjust.
Identities = 303/338 (90%), Positives = 322/338 (96%), Gaps = 1/338 (0%)
Query 1 MTD-MWDVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFN 59
M+D ++DVRITDTSLRDGSHHKRHQFT +EV AIVAA+DAAGVPVIEVTHGDGLGGSSFN
Sbjct 1 MSDHIFDVRITDTSLRDGSHHKRHQFTPEEVAAIVAAIDAAGVPVIEVTHGDGLGGSSFN 60
Query 60 YGFSKTPEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADV 119
YGFSKTP+QELI+LAA TA +A+IAFLMLPGV TK+D+KEA+ NGG ICRIATHCTEADV
Sbjct 61 YGFSKTPDQELIRLAAQTANDAKIAFLMLPGVATKEDMKEAQGNGGQICRIATHCTEADV 120
Query 120 SIQHFGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVA 179
SIQHFGLARELGLETVGFLMMAHTI PEKLAAQARIMADAGCQCVYVVDSAGALVL+GV
Sbjct 121 SIQHFGLARELGLETVGFLMMAHTIPPEKLAAQARIMADAGCQCVYVVDSAGALVLEGVR 180
Query 180 DRVSALVAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEA 239
DRV+ALVAELG DAQVGFHGHENLGLGVANS+ AVRAGAKQIDGS RRFGAGAGNAPVEA
Sbjct 181 DRVAALVAELGGDAQVGFHGHENLGLGVANSLEAVRAGAKQIDGSVRRFGAGAGNAPVEA 240
Query 240 LIGVFDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQ 299
LIGVFDK+G+KTGIDFFDIADAAEDVVRPAMPAEC+LDRNALIMGYSGVYSSFLKHAVRQ
Sbjct 241 LIGVFDKVGIKTGIDFFDIADAAEDVVRPAMPAECVLDRNALIMGYSGVYSSFLKHAVRQ 300
Query 300 AERYGVPASALLHRAGQRKLIGGQEDQLIDIALEIKRE 337
ERYGVPA LLHRAGQRKLIGGQEDQLIDIALEI+RE
Sbjct 301 GERYGVPAHELLHRAGQRKLIGGQEDQLIDIALEIQRE 338
>gi|226304230|ref|YP_002764188.1| 4-hydroxy-2-oxovalerate aldolase [Rhodococcus erythropolis PR4]
gi|263429923|sp|C0ZPX1.1|HOA1_RHOE4 RecName: Full=4-hydroxy-2-oxovalerate aldolase 1; Short=HOA 1;
AltName: Full=4-hydroxy-2-keto-pentanoic acid aldolase 1;
AltName: Full=4-hydroxy-2-oxopentanoate aldolase 1
gi|226183345|dbj|BAH31449.1| 4-hydroxy-2-oxovalerate aldolase [Rhodococcus erythropolis PR4]
Length=347
Score = 582 bits (1499), Expect = 4e-164, Method: Compositional matrix adjust.
Identities = 287/343 (84%), Positives = 307/343 (90%), Gaps = 6/343 (1%)
Query 1 MTDM------WDVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLG 54
M+DM WD+R+TDTSLRDGSHHKRHQFT +EV AIV ALD AGVPVIEVTHGDGLG
Sbjct 1 MSDMIHFDSSWDIRVTDTSLRDGSHHKRHQFTVEEVRAIVGALDGAGVPVIEVTHGDGLG 60
Query 55 GSSFNYGFSKTPEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHC 114
GSSFNYGFSKTPEQELIK A TA A+IAFLMLPG+G KDDI A+DNG SICRIATHC
Sbjct 61 GSSFNYGFSKTPEQELIKAAVETATNAKIAFLMLPGLGIKDDIVIAQDNGASICRIATHC 120
Query 115 TEADVSIQHFGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALV 174
TEADVSIQHFGLARE GLETVGFLMMAH+I PEKLA QARIMADAGCQCVYVVDSAGALV
Sbjct 121 TEADVSIQHFGLARERGLETVGFLMMAHSIPPEKLAKQARIMADAGCQCVYVVDSAGALV 180
Query 175 LDGVADRVSALVAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGN 234
L+ V+DRV ALV ELG DAQVGFHGHENLGLGVANS+AAVRAGAKQIDGS RRFGAGAGN
Sbjct 181 LEQVSDRVEALVQELGNDAQVGFHGHENLGLGVANSIAAVRAGAKQIDGSTRRFGAGAGN 240
Query 235 APVEALIGVFDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLK 294
APVEA +GV DKIGVKTGIDFF IADAAEDVVRPAMP ECLLDR AL+MGY+GVYSSFLK
Sbjct 241 APVEAFVGVCDKIGVKTGIDFFAIADAAEDVVRPAMPQECLLDRQALMMGYAGVYSSFLK 300
Query 295 HAVRQAERYGVPASALLHRAGQRKLIGGQEDQLIDIALEIKRE 337
HA RQAERYGV ++ LL RAG+RKL+GGQEDQLIDIALE++RE
Sbjct 301 HAERQAERYGVSSAELLVRAGKRKLVGGQEDQLIDIALELQRE 343
>gi|226363860|ref|YP_002781642.1| 4-hydroxy-2-ketovalerate aldolase [Rhodococcus opacus B4]
gi|263430582|sp|C1BAJ4.1|HOA3_RHOOB RecName: Full=4-hydroxy-2-oxovalerate aldolase 3; Short=HOA 3;
AltName: Full=4-hydroxy-2-keto-pentanoic acid aldolase 3;
AltName: Full=4-hydroxy-2-oxopentanoate aldolase 3
gi|226242349|dbj|BAH52697.1| 4-hydroxy-2-oxovalerate aldolase [Rhodococcus opacus B4]
Length=339
Score = 582 bits (1499), Expect = 4e-164, Method: Compositional matrix adjust.
Identities = 284/337 (85%), Positives = 307/337 (92%), Gaps = 0/337 (0%)
Query 1 MTDMWDVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNY 60
M+ WD+R+TDTSLRDGSHHKRHQFT DEV AIV ALD+AGVPVIEVTHGDGLGGSSFNY
Sbjct 1 MSSSWDIRVTDTSLRDGSHHKRHQFTGDEVRAIVGALDSAGVPVIEVTHGDGLGGSSFNY 60
Query 61 GFSKTPEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVS 120
GFSK PEQELI +A TA+ A+IAFLMLPG+G KDDI A+DNG SICRIATHCTEADVS
Sbjct 61 GFSKVPEQELISIAVDTARNAKIAFLMLPGLGIKDDIIVAQDNGASICRIATHCTEADVS 120
Query 121 IQHFGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVAD 180
IQHFGLAR+ GLETVGFLMMAH+I PEKLA QARIMADAGCQCVYVVDSAGALVL+ V+D
Sbjct 121 IQHFGLARDRGLETVGFLMMAHSIPPEKLARQARIMADAGCQCVYVVDSAGALVLEQVSD 180
Query 181 RVSALVAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEAL 240
RV ALV ELG DAQVGFHGHENLGLGVANS+AAVRAGAKQIDGS RRFGAGAGNAPVEA
Sbjct 181 RVEALVQELGADAQVGFHGHENLGLGVANSIAAVRAGAKQIDGSTRRFGAGAGNAPVEAF 240
Query 241 IGVFDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQA 300
+GV DKIGVKTGIDFF IADAAEDVVRPAMPAECLLDR AL+MGY+GVYSSFLKHA RQA
Sbjct 241 VGVCDKIGVKTGIDFFAIADAAEDVVRPAMPAECLLDRQALMMGYAGVYSSFLKHAERQA 300
Query 301 ERYGVPASALLHRAGQRKLIGGQEDQLIDIALEIKRE 337
ERYGV ++ LL RAG+RKL+GGQEDQLIDIALE++RE
Sbjct 301 ERYGVSSAELLVRAGKRKLVGGQEDQLIDIALELQRE 337
>gi|111021507|ref|YP_704479.1| 4-hydroxy-2-ketovalerate aldolase [Rhodococcus jostii RHA1]
gi|122955482|sp|Q0S815.1|HOA3_RHOSR RecName: Full=4-hydroxy-2-oxovalerate aldolase 3; Short=HOA 3;
AltName: Full=4-hydroxy-2-keto-pentanoic acid aldolase 3;
AltName: Full=4-hydroxy-2-oxopentanoate aldolase 3
gi|110821037|gb|ABG96321.1| 4-hydroxy-2-oxovalerate aldolase [Rhodococcus jostii RHA1]
Length=339
Score = 581 bits (1498), Expect = 5e-164, Method: Compositional matrix adjust.
Identities = 285/337 (85%), Positives = 306/337 (91%), Gaps = 0/337 (0%)
Query 1 MTDMWDVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNY 60
M WD+R+TDTSLRDGSHHKRHQFT +EV AIV ALD AGVPVIEVTHGDGLGGSSFNY
Sbjct 1 MRSSWDIRVTDTSLRDGSHHKRHQFTGEEVRAIVGALDHAGVPVIEVTHGDGLGGSSFNY 60
Query 61 GFSKTPEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVS 120
GFSK PEQELI +A TAK A+IAFLMLPG+G KDDI A+DNG SICRIATHCTEADVS
Sbjct 61 GFSKVPEQELISIAVDTAKNAKIAFLMLPGLGIKDDIIVAQDNGASICRIATHCTEADVS 120
Query 121 IQHFGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVAD 180
IQHFGLAR+ GLETVGFLMMAH+IAPEKLA QARIMADAGCQCVYVVDSAGALVL+ V+D
Sbjct 121 IQHFGLARDRGLETVGFLMMAHSIAPEKLAKQARIMADAGCQCVYVVDSAGALVLEQVSD 180
Query 181 RVSALVAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEAL 240
RV ALV ELG DAQVGFHGHENLGLGVANS+AAVRAGAKQIDGS RRFGAGAGNAPVEA
Sbjct 181 RVEALVQELGSDAQVGFHGHENLGLGVANSIAAVRAGAKQIDGSTRRFGAGAGNAPVEAF 240
Query 241 IGVFDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQA 300
+GV DKIGVKTGIDFF IADAAEDVVRPAMPAECLLDR AL+MGY+GVYSSFLKHA RQA
Sbjct 241 VGVCDKIGVKTGIDFFAIADAAEDVVRPAMPAECLLDRQALMMGYAGVYSSFLKHAERQA 300
Query 301 ERYGVPASALLHRAGQRKLIGGQEDQLIDIALEIKRE 337
ERYGV ++ LL RAG+RKL+GGQEDQLIDIALE++RE
Sbjct 301 ERYGVSSAELLVRAGKRKLVGGQEDQLIDIALELQRE 337
>gi|241992735|gb|ACS73886.1| HsaF [Rhodococcus ruber]
Length=352
Score = 579 bits (1492), Expect = 2e-163, Method: Compositional matrix adjust.
Identities = 279/336 (84%), Positives = 306/336 (92%), Gaps = 0/336 (0%)
Query 5 WDVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFSK 64
WD+R+TDTSLRDGSHHKRHQF ++EV A+VAALD +GVPVIEVTHGDGLGGSSFNYGFSK
Sbjct 16 WDIRVTDTSLRDGSHHKRHQFDREEVRAVVAALDLSGVPVIEVTHGDGLGGSSFNYGFSK 75
Query 65 TPEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVSIQHF 124
PEQELIK+A TA+ A+IAFLMLPGVG K+DI EA+DNG SICRIATHCTEADVS+QHF
Sbjct 76 VPEQELIKIAVDTAQHAKIAFLMLPGVGIKEDIVEAQDNGASICRIATHCTEADVSVQHF 135
Query 125 GLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVSA 184
GLARE GLETVGFLMMAHT+ PEKLA QARIMADAGCQCVYVVDSAGALVL+ V +RV A
Sbjct 136 GLARERGLETVGFLMMAHTVTPEKLAEQARIMADAGCQCVYVVDSAGALVLEQVTERVEA 195
Query 185 LVAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEALIGVF 244
LVAELG DAQVGFHGHENLGLGVANS+AAVRAGA+QIDGS RRFGAGAGN PVEA +GV
Sbjct 196 LVAELGSDAQVGFHGHENLGLGVANSIAAVRAGARQIDGSARRFGAGAGNTPVEAFVGVC 255
Query 245 DKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQAERYG 304
DK+G+KTGIDFF IADAAEDVVRP MPAECLLDR AL+MGY+GVYSSFL+HA RQAERYG
Sbjct 256 DKVGIKTGIDFFAIADAAEDVVRPVMPAECLLDRQALMMGYAGVYSSFLRHAERQAERYG 315
Query 305 VPASALLHRAGQRKLIGGQEDQLIDIALEIKRELDS 340
V A+ LL RAG+RKLIGGQEDQLIDIALE++RE S
Sbjct 316 VSAAELLVRAGKRKLIGGQEDQLIDIALELQREQQS 351
>gi|229494382|ref|ZP_04388145.1| 4-hydroxy-2-oxovalerate aldolase [Rhodococcus erythropolis SK121]
gi|229318744|gb|EEN84602.1| 4-hydroxy-2-oxovalerate aldolase [Rhodococcus erythropolis SK121]
Length=344
Score = 578 bits (1490), Expect = 4e-163, Method: Compositional matrix adjust.
Identities = 284/333 (86%), Positives = 302/333 (91%), Gaps = 0/333 (0%)
Query 5 WDVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFSK 64
WD+R+TDTSLRDGSHHKRHQFT EV AIV ALD AGVPVIEVTHGDGLGGSSFNYGFSK
Sbjct 8 WDIRVTDTSLRDGSHHKRHQFTVVEVRAIVGALDGAGVPVIEVTHGDGLGGSSFNYGFSK 67
Query 65 TPEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVSIQHF 124
TPEQELIK A TA A+IAFLMLPG+G KDDI A+DNG SICRIATHCTEADVSIQHF
Sbjct 68 TPEQELIKAAVETATNAKIAFLMLPGLGIKDDIVIAQDNGASICRIATHCTEADVSIQHF 127
Query 125 GLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVSA 184
GLARE GLETVGFLMMAH+I PEKLA QARIMADAGCQCVYVVDSAGALVL+ V+DRV A
Sbjct 128 GLARERGLETVGFLMMAHSIPPEKLAKQARIMADAGCQCVYVVDSAGALVLEQVSDRVEA 187
Query 185 LVAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEALIGVF 244
LV ELG DAQVGFHGHENLGLGVANS+AAVRAGAKQIDGS RRFGAGAGNAPVEA +GV
Sbjct 188 LVQELGNDAQVGFHGHENLGLGVANSIAAVRAGAKQIDGSTRRFGAGAGNAPVEAFVGVC 247
Query 245 DKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQAERYG 304
DKIGVKTGIDFF IADAAEDVVRPAMP ECLLDR AL+MGY+GVYSSFLKHA RQAERYG
Sbjct 248 DKIGVKTGIDFFAIADAAEDVVRPAMPQECLLDRQALMMGYAGVYSSFLKHAERQAERYG 307
Query 305 VPASALLHRAGQRKLIGGQEDQLIDIALEIKRE 337
V ++ LL RAG+RKL+GGQEDQLIDIALE++RE
Sbjct 308 VSSAELLVRAGKRKLVGGQEDQLIDIALELQRE 340
>gi|238481729|gb|ACR43932.1| 4-hydroxy-2-oxovalerate aldolase [Rhodococcus sp. CECT 3014]
Length=333
Score = 564 bits (1454), Expect = 6e-159, Method: Compositional matrix adjust.
Identities = 279/333 (84%), Positives = 297/333 (90%), Gaps = 6/333 (1%)
Query 1 MTDM------WDVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLG 54
M+DM WD+R+TDTSLRDGSHHKRHQFT +EV AIV ALD AGVPVIEVTHGDGLG
Sbjct 1 MSDMIHFDSSWDIRVTDTSLRDGSHHKRHQFTVEEVRAIVGALDGAGVPVIEVTHGDGLG 60
Query 55 GSSFNYGFSKTPEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHC 114
GSSFNYGFSKTPEQELIK A TA A+IAFLMLPG+G KDDI A+DNG SICRIATHC
Sbjct 61 GSSFNYGFSKTPEQELIKAAVETATNAKIAFLMLPGLGIKDDIVIAQDNGASICRIATHC 120
Query 115 TEADVSIQHFGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALV 174
TEADVSIQHFGLARE GLETVGFLMMAH+I PEKLA QARIMADAGCQCVYVVDSAGALV
Sbjct 121 TEADVSIQHFGLARERGLETVGFLMMAHSIPPEKLAKQARIMADAGCQCVYVVDSAGALV 180
Query 175 LDGVADRVSALVAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGN 234
L+ V+DRV ALV ELG DAQVGFHGHENLGLGVANS+AAVRAGAKQIDGS RRFGAGAGN
Sbjct 181 LEQVSDRVEALVQELGNDAQVGFHGHENLGLGVANSIAAVRAGAKQIDGSTRRFGAGAGN 240
Query 235 APVEALIGVFDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLK 294
APVEA +GV DKIGVKTGIDFF IADAAEDVVRPAMP ECLLDR AL+MGY+GVYSSFLK
Sbjct 241 APVEAFVGVCDKIGVKTGIDFFAIADAAEDVVRPAMPQECLLDRQALMMGYAGVYSSFLK 300
Query 295 HAVRQAERYGVPASALLHRAGQRKLIGGQEDQL 327
HA RQAERYGV ++ LL RAG+RKL+GGQEDQL
Sbjct 301 HAERQAERYGVSSAELLVRAGKRKLVGGQEDQL 333
>gi|54022431|ref|YP_116673.1| 4-hydroxy-2-ketovalerate aldolase [Nocardia farcinica IFM 10152]
gi|81376184|sp|Q5Z2N2.1|HOA1_NOCFA RecName: Full=4-hydroxy-2-oxovalerate aldolase 1; Short=HOA 1;
AltName: Full=4-hydroxy-2-keto-pentanoic acid aldolase 1;
AltName: Full=4-hydroxy-2-oxopentanoate aldolase 1
gi|54013939|dbj|BAD55309.1| putative 4-hydroxy-2-oxovalerate aldolase [Nocardia farcinica
IFM 10152]
Length=345
Score = 564 bits (1454), Expect = 7e-159, Method: Compositional matrix adjust.
Identities = 272/333 (82%), Positives = 302/333 (91%), Gaps = 0/333 (0%)
Query 5 WDVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFSK 64
D+R+TDTSLRDGSHHKRHQFT EV IVAALD AGVPVIEVTHGDGLGGSSFNYGFSK
Sbjct 7 LDIRVTDTSLRDGSHHKRHQFTATEVRDIVAALDGAGVPVIEVTHGDGLGGSSFNYGFSK 66
Query 65 TPEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVSIQHF 124
TPEQEL+ +AA TAK+A+IA LMLPGVG K+DIK ++DNG SICRIATHCTEADVSIQHF
Sbjct 67 TPEQELVTIAAQTAKQAKIAVLMLPGVGVKEDIKVSQDNGASICRIATHCTEADVSIQHF 126
Query 125 GLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVSA 184
GLARELGLETVGFLMM+HT PE LA QARIMADAGCQCVY+VDSAGALVL+ V+DRV+A
Sbjct 127 GLARELGLETVGFLMMSHTQPPEVLAKQARIMADAGCQCVYIVDSAGALVLEQVSDRVAA 186
Query 185 LVAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEALIGVF 244
+VAELG+DAQVGFHGHENL L VANS+ A+RAGA QIDGS RRFGAGAGN PVEAL+GV
Sbjct 187 VVAELGDDAQVGFHGHENLDLAVANSIYAIRAGATQIDGSARRFGAGAGNTPVEALVGVC 246
Query 245 DKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQAERYG 304
DK+G++TGIDFF IADAAEDVVRPAMP ECLLDR AL+MGY+GVYSSFLKHA RQAERYG
Sbjct 247 DKLGIRTGIDFFAIADAAEDVVRPAMPQECLLDRQALMMGYAGVYSSFLKHAERQAERYG 306
Query 305 VPASALLHRAGQRKLIGGQEDQLIDIALEIKRE 337
V A+ +L RAG+RKL+GGQEDQLIDIALE++RE
Sbjct 307 VSAAEMLVRAGRRKLVGGQEDQLIDIALELQRE 339
>gi|262200908|ref|YP_003272116.1| 4-hydroxy-2-oxovalerate aldolase [Gordonia bronchialis DSM 43247]
gi|262084255|gb|ACY20223.1| 4-hydroxy-2-oxovalerate aldolase [Gordonia bronchialis DSM 43247]
Length=358
Score = 555 bits (1429), Expect = 6e-156, Method: Compositional matrix adjust.
Identities = 266/343 (78%), Positives = 304/343 (89%), Gaps = 0/343 (0%)
Query 2 TDMWDVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYG 61
+D D+RITD+SLRDGSHHKRHQFT+DEV +IV ALD AGVPVIEVTHGDGLGGSSFNYG
Sbjct 16 SDTLDIRITDSSLRDGSHHKRHQFTEDEVRSIVGALDEAGVPVIEVTHGDGLGGSSFNYG 75
Query 62 FSKTPEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVSI 121
FSKTPEQ+LIK AA TAK+A+IAFLMLPG+GTKDDI+ A+DNGG ICRIATHCTEADVSI
Sbjct 76 FSKTPEQQLIKAAAETAKQAKIAFLMLPGLGTKDDIRAAQDNGGQICRIATHCTEADVSI 135
Query 122 QHFGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADR 181
QHFGLAR+LGLETVGFLMM+H+ PE LAAQARIMADAGCQCVYVVDSAGALVL+ V R
Sbjct 136 QHFGLARDLGLETVGFLMMSHSQPPEVLAAQARIMADAGCQCVYVVDSAGALVLEDVTVR 195
Query 182 VSALVAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEALI 241
V ALVAELG+DAQVGFHGHENL + VANS+ A+RAGA+QIDGS RRFGAGAGN P EA +
Sbjct 196 VQALVAELGDDAQVGFHGHENLDIAVANSINAIRAGAQQIDGSIRRFGAGAGNTPTEAFV 255
Query 242 GVFDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQAE 301
GV DK+G+ TG+DF IADAA+DVVRPAMP+ECL+DR+A++MGY+G YSSFLKHA AE
Sbjct 256 GVCDKLGITTGVDFMKIADAAQDVVRPAMPSECLVDRSAMMMGYAGCYSSFLKHAEGHAE 315
Query 302 RYGVPASALLHRAGQRKLIGGQEDQLIDIALEIKRELDSGAAV 344
RYGV A+ +L AG RKL+GGQEDQLIDIALE+K++ D+ A V
Sbjct 316 RYGVSAAEILIEAGNRKLVGGQEDQLIDIALELKKKADANAGV 358
>gi|343925861|ref|ZP_08765376.1| putative 4-hydroxy-2-oxovalerate aldolase [Gordonia alkanivorans
NBRC 16433]
gi|343764212|dbj|GAA12302.1| putative 4-hydroxy-2-oxovalerate aldolase [Gordonia alkanivorans
NBRC 16433]
Length=364
Score = 545 bits (1403), Expect = 6e-153, Method: Compositional matrix adjust.
Identities = 262/343 (77%), Positives = 297/343 (87%), Gaps = 0/343 (0%)
Query 2 TDMWDVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYG 61
+D D+RITD+SLRDGSHHKRHQFT++EV AIV LD AGVPVIEVTHGDGLGGSSFNYG
Sbjct 22 SDTLDIRITDSSLRDGSHHKRHQFTEEEVRAIVGGLDEAGVPVIEVTHGDGLGGSSFNYG 81
Query 62 FSKTPEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVSI 121
FSKTPEQ+LIK AA TAK A+IAFLMLPG+GTKDDI+ A+DNGG ICRIATHCTEADVSI
Sbjct 82 FSKTPEQQLIKAAAETAKRAKIAFLMLPGLGTKDDIRAAQDNGGQICRIATHCTEADVSI 141
Query 122 QHFGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADR 181
QHFGLAR+LGLETVGFLMM+H+ PE +A QARIMADAGCQCVYVVDSAGALVL+ V R
Sbjct 142 QHFGLARDLGLETVGFLMMSHSQPPEVIAKQARIMADAGCQCVYVVDSAGALVLEDVTVR 201
Query 182 VSALVAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEALI 241
V ALVAELG DAQVGFHGHENL + +ANSV A+RAGA+QIDGS RRFGAGAGN P EA +
Sbjct 202 VEALVAELGNDAQVGFHGHENLDIAIANSVNAIRAGAQQIDGSIRRFGAGAGNTPTEAFV 261
Query 242 GVFDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQAE 301
GV DK+G+ TG+DF IAD A+DVVRPAMP ECL+DR A++MGY+G YSSFLKHA AE
Sbjct 262 GVCDKLGITTGVDFMKIADVAQDVVRPAMPTECLVDRPAMMMGYAGCYSSFLKHAEGHAE 321
Query 302 RYGVPASALLHRAGQRKLIGGQEDQLIDIALEIKRELDSGAAV 344
RYGV A+ +L AG RKL+GGQEDQLIDIALE+K++ D+ A V
Sbjct 322 RYGVSAAEILLEAGARKLVGGQEDQLIDIALELKKKQDANAGV 364
>gi|319948620|ref|ZP_08022744.1| 4-hyroxy-2-oxovalerate/4-hydroxy-2-oxopentanoic acid aldolase
[Dietzia cinnamea P4]
gi|319437701|gb|EFV92697.1| 4-hyroxy-2-oxovalerate/4-hydroxy-2-oxopentanoic acid aldolase
[Dietzia cinnamea P4]
Length=354
Score = 538 bits (1387), Expect = 4e-151, Method: Compositional matrix adjust.
Identities = 257/337 (77%), Positives = 298/337 (89%), Gaps = 0/337 (0%)
Query 2 TDMWDVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYG 61
+D D+RITD+SLRDGSHHKRHQF+ ++V +VAALD AGVPVIEVTHGDGLGG+SFNYG
Sbjct 15 SDELDIRITDSSLRDGSHHKRHQFSVEDVRNVVAALDGAGVPVIEVTHGDGLGGASFNYG 74
Query 62 FSKTPEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVSI 121
F+K+ +QELIK AA TA +A+IAFL LPG+G KDDI +ARDNGGSICR+ATHCTEADVSI
Sbjct 75 FAKSYDQELIKAAAETATQAKIAFLTLPGLGIKDDILKARDNGGSICRVATHCTEADVSI 134
Query 122 QHFGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADR 181
QHFG ARELGLETVGFLMM+HT PE LA QARIMADAGCQCVY+VDSAGALV+D V+DR
Sbjct 135 QHFGYARELGLETVGFLMMSHTQPPEVLAKQARIMADAGCQCVYIVDSAGALVMDQVSDR 194
Query 182 VSALVAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEALI 241
VSALVAELG+DAQVGFHGHENL +GV NS+ A+RAGA+QIDGS RRFGAGAGN PVEAL+
Sbjct 195 VSALVAELGDDAQVGFHGHENLDIGVGNSIMAIRAGAQQIDGSTRRFGAGAGNTPVEALV 254
Query 242 GVFDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQAE 301
G DK+ ++TGIDFF IADAAEDVVRP MP EC++DR A+++GY+G YSSFLKHA A+
Sbjct 255 GCCDKLDIRTGIDFFKIADAAEDVVRPLMPNECIVDRQAMMLGYAGCYSSFLKHAEGHAQ 314
Query 302 RYGVPASALLHRAGQRKLIGGQEDQLIDIALEIKREL 338
RY VPAS +L RAG+R L+GGQEDQLIDIALEI++EL
Sbjct 315 RYNVPASEILIRAGERLLVGGQEDQLIDIALEIQKEL 351
>gi|269127676|ref|YP_003301046.1| 4-hydroxy-2-oxovalerate aldolase [Thermomonospora curvata DSM
43183]
gi|268312634|gb|ACY99008.1| 4-hydroxy-2-oxovalerate aldolase [Thermomonospora curvata DSM
43183]
Length=344
Score = 534 bits (1375), Expect = 1e-149, Method: Compositional matrix adjust.
Identities = 257/336 (77%), Positives = 291/336 (87%), Gaps = 0/336 (0%)
Query 2 TDMWDVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYG 61
+D D+R+TD+SLRDGSH KRHQFT D V ++VAALD AGVPVIEV HGDGLGGSSF YG
Sbjct 5 SDTLDIRVTDSSLRDGSHAKRHQFTVDHVTSVVAALDEAGVPVIEVAHGDGLGGSSFTYG 64
Query 62 FSKTPEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVSI 121
FSKTPEQELIK A TA A+IAFLMLPGVG KDDI+EA DNG ICRIATHCTEADVS+
Sbjct 65 FSKTPEQELIKAAVKTATRAKIAFLMLPGVGVKDDIREAADNGAQICRIATHCTEADVSV 124
Query 122 QHFGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADR 181
QHFGLAR+LGLETVGFLMMAH+ PE LA QARIMADAGCQCVYVVDSAGAL+L+ +DR
Sbjct 125 QHFGLARDLGLETVGFLMMAHSQPPEVLAKQARIMADAGCQCVYVVDSAGALILEETSDR 184
Query 182 VSALVAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEALI 241
++ALVAELG+DAQVGFHGHENLGLGVANS+AAVRAGAKQIDGS RR GAGAGN P+EA I
Sbjct 185 IAALVAELGDDAQVGFHGHENLGLGVANSIAAVRAGAKQIDGSVRRLGAGAGNTPLEAFI 244
Query 242 GVFDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQAE 301
V DK+G++TG+D F I DAAEDVVRP M +ECLL R ++MGY+GVYSSFLKHA R AE
Sbjct 245 AVCDKLGIRTGVDVFKIVDAAEDVVRPVMDSECLLGRMEIMMGYAGVYSSFLKHADRLAE 304
Query 302 RYGVPASALLHRAGQRKLIGGQEDQLIDIALEIKRE 337
RYGV + +L RAG+RKL+GGQEDQLIDIA+E+ +E
Sbjct 305 RYGVSGAQILVRAGERKLVGGQEDQLIDIAIELAKE 340
>gi|111022764|ref|YP_705736.1| 4-hydroxy-2-ketovalerate aldolase [Rhodococcus jostii RHA1]
gi|123144313|sp|Q0S4F8.1|HOA4_RHOSR RecName: Full=4-hydroxy-2-oxovalerate aldolase 4; Short=HOA 4;
AltName: Full=4-hydroxy-2-keto-pentanoic acid aldolase 4;
AltName: Full=4-hydroxy-2-oxopentanoate aldolase 4
gi|110822294|gb|ABG97578.1| 4-hydroxy-2-oxovalerate aldolase [Rhodococcus jostii RHA1]
Length=352
Score = 513 bits (1322), Expect = 1e-143, Method: Compositional matrix adjust.
Identities = 254/340 (75%), Positives = 287/340 (85%), Gaps = 0/340 (0%)
Query 5 WDVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFSK 64
D+R+TD+SLRDGSH KRHQFT + V +IV ALDAAGVPVIEVTHGDGLGGSSFNYGFS
Sbjct 7 LDIRVTDSSLRDGSHAKRHQFTVEHVRSIVGALDAAGVPVIEVTHGDGLGGSSFNYGFSH 66
Query 65 TPEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVSIQHF 124
TPEQELIK A TA+ ARIAFLMLPG+G + DI+EA DNG SICRIATHCTEAD+S+QHF
Sbjct 67 TPEQELIKAAVETAERARIAFLMLPGLGVQSDIREAADNGASICRIATHCTEADISVQHF 126
Query 125 GLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVSA 184
GLARELGLETVGFLMM+H+ PE LA QARIMADAGCQCVYVVDSAGAL+L+ V+DRVSA
Sbjct 127 GLARELGLETVGFLMMSHSQPPEVLAKQARIMADAGCQCVYVVDSAGALILNAVSDRVSA 186
Query 185 LVAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEALIGVF 244
LVAELG+DAQVGFHGHENLGLGVANSV AV AGA QIDGS RRFGAGAGN PVEA V
Sbjct 187 LVAELGDDAQVGFHGHENLGLGVANSVLAVEAGALQIDGSTRRFGAGAGNTPVEAFAAVT 246
Query 245 DKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQAERYG 304
+K+G++TGID I DAAEDVVRP M +C LDR +L+MGY+GVYSSFLKHA A RYG
Sbjct 247 EKLGIRTGIDTLKIIDAAEDVVRPIMDGDCQLDRLSLMMGYAGVYSSFLKHADSHARRYG 306
Query 305 VPASALLHRAGQRKLIGGQEDQLIDIALEIKRELDSGAAV 344
V + +L AG+RKL+GGQEDQLI+IAL + +G+AV
Sbjct 307 VSGAEILIEAGRRKLVGGQEDQLIEIALGLADRGPAGSAV 346
>gi|311744294|ref|ZP_07718098.1| 4-hydroxy-2-oxovalerate aldolase [Aeromicrobium marinum DSM 15272]
gi|311312467|gb|EFQ82380.1| 4-hydroxy-2-oxovalerate aldolase [Aeromicrobium marinum DSM 15272]
Length=356
Score = 513 bits (1322), Expect = 1e-143, Method: Compositional matrix adjust.
Identities = 259/330 (79%), Positives = 286/330 (87%), Gaps = 0/330 (0%)
Query 6 DVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFSKT 65
D+R+TDT LRDGSHHKRHQF DEV +IV ALDAAG+PVIEVTHGDGLGGSSFNYGFS+T
Sbjct 22 DLRLTDTCLRDGSHHKRHQFVPDEVRSIVGALDAAGIPVIEVTHGDGLGGSSFNYGFSRT 81
Query 66 PEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVSIQHFG 125
PEQELIKLAA TA ARIAFLMLPGVGTKDDI+ A+DNGG ICRIATHCTEAD S QHFG
Sbjct 82 PEQELIKLAAETATRARIAFLMLPGVGTKDDIRAAQDNGGQICRIATHCTEADTSRQHFG 141
Query 126 LARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVSAL 185
LARELGLETVGFLMM+HT +PE LA QARIM DAGCQCVYVVDSAGALV++GVADRV+A+
Sbjct 142 LARELGLETVGFLMMSHTQSPETLARQARIMVDAGCQCVYVVDSAGALVMEGVADRVAAV 201
Query 186 VAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEALIGVFD 245
VAE+G +A VGFHGHENLGLGVAN+V A RAGA QIDGS RRFGAGAGN P+EA IGV D
Sbjct 202 VAEIGGEATVGFHGHENLGLGVANTVIAARAGATQIDGSVRRFGAGAGNTPLEAFIGVAD 261
Query 246 KIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQAERYGV 305
K+G TG+DF I DAAEDVVRPAMP EC L+R L+MGY+GVYSSFLKHA AERY V
Sbjct 262 KLGWNTGVDFLQIVDAAEDVVRPAMPEECTLNRMTLMMGYAGVYSSFLKHAGNAAERYDV 321
Query 306 PASALLHRAGQRKLIGGQEDQLIDIALEIK 335
+ +L AG+R+LIGGQEDQLIDIAL +K
Sbjct 322 SGAKILLEAGRRQLIGGQEDQLIDIALMLK 351
>gi|226365271|ref|YP_002783054.1| 4-hydroxy-2-ketovalerate aldolase [Rhodococcus opacus B4]
gi|263430630|sp|C1AYB4.1|HOA5_RHOOB RecName: Full=4-hydroxy-2-oxovalerate aldolase 5; Short=HOA 5;
AltName: Full=4-hydroxy-2-keto-pentanoic acid aldolase 5;
AltName: Full=4-hydroxy-2-oxopentanoate aldolase 5
gi|226243761|dbj|BAH54109.1| 4-hydroxy-2-oxovalerate aldolase [Rhodococcus opacus B4]
Length=352
Score = 513 bits (1322), Expect = 1e-143, Method: Compositional matrix adjust.
Identities = 250/328 (77%), Positives = 282/328 (86%), Gaps = 0/328 (0%)
Query 5 WDVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFSK 64
D+R+TD+SLRDGSH KRHQFT + V +IV ALDAAGVPVIEVTHGDGLGGSSFNYGFS
Sbjct 7 LDIRVTDSSLRDGSHAKRHQFTVEHVRSIVGALDAAGVPVIEVTHGDGLGGSSFNYGFSH 66
Query 65 TPEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVSIQHF 124
TPEQELIK A TA++A+IAFLMLPG+G + DI+EA DNG SICRIATHCTEAD+S+QHF
Sbjct 67 TPEQELIKAAVETAEQAKIAFLMLPGLGVRSDIREAADNGASICRIATHCTEADISVQHF 126
Query 125 GLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVSA 184
GLAR+LGLETVGFLMM+H+ PE LA QARIMADAGCQCVYVVDSAGAL+L+ V+DRVSA
Sbjct 127 GLARDLGLETVGFLMMSHSQPPEVLAKQARIMADAGCQCVYVVDSAGALILNAVSDRVSA 186
Query 185 LVAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEALIGVF 244
LVAELG+DAQVGFHGHENLGLGVANSV AV AGA QIDGS RRFGAGAGN PVEA V
Sbjct 187 LVAELGDDAQVGFHGHENLGLGVANSVLAVEAGALQIDGSTRRFGAGAGNTPVEAFAAVT 246
Query 245 DKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQAERYG 304
+K+G++TGID I DAAEDVVRP M +CLLDR +L MGY+GVYSSFLKHA A RYG
Sbjct 247 EKLGIRTGIDTLKIIDAAEDVVRPIMDGDCLLDRLSLTMGYAGVYSSFLKHADSHASRYG 306
Query 305 VPASALLHRAGQRKLIGGQEDQLIDIAL 332
V + +L AG+RKL+GGQEDQLI+IAL
Sbjct 307 VSGAEILIEAGRRKLVGGQEDQLIEIAL 334
>gi|284041912|ref|YP_003392252.1| 4-hydroxy-2-oxovalerate aldolase [Conexibacter woesei DSM 14684]
gi|283946133|gb|ADB48877.1| 4-hydroxy-2-oxovalerate aldolase [Conexibacter woesei DSM 14684]
Length=349
Score = 457 bits (1176), Expect = 1e-126, Method: Compositional matrix adjust.
Identities = 231/322 (72%), Positives = 271/322 (85%), Gaps = 0/322 (0%)
Query 5 WDVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFSK 64
DVR+TDT LRDGSH H+FT+++V +VAALDAAGVPV+EVTHGDGLGGSS+NYGFS
Sbjct 11 LDVRVTDTCLRDGSHAVGHRFTREQVRDVVAALDAAGVPVLEVTHGDGLGGSSYNYGFSG 70
Query 65 TPEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVSIQHF 124
TPE+ELI A ATA+ ARIA LMLPGVGT DDI+ D G + R+ATHCTEADV+IQHF
Sbjct 71 TPERELIATAVATARRARIAALMLPGVGTADDIRAVADLGVEVIRVATHCTEADVAIQHF 130
Query 125 GLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVSA 184
GLARELGLETVGFLMM+H+ P+ LAAQAR+MADAGCQCVYVVDSAGALVL+ VA+RV A
Sbjct 131 GLARELGLETVGFLMMSHSQPPDVLAAQARVMADAGCQCVYVVDSAGALVLEQVAERVEA 190
Query 185 LVAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEALIGVF 244
+ AELG+DAQVGFHGHENLGL +AN+VAAVRAGA Q+DG RR GAGAGN P EAL V
Sbjct 191 VGAELGDDAQVGFHGHENLGLAIANTVAAVRAGAAQVDGCTRRLGAGAGNTPTEALAAVC 250
Query 245 DKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQAERYG 304
+K+G++TG+D +ADAAE+VVRPAM AEC LDR AL++GY+GVYSSFLKHA R AERYG
Sbjct 251 EKLGIETGLDVLALADAAEEVVRPAMAAECTLDRGALLLGYAGVYSSFLKHAERSAERYG 310
Query 305 VPASALLHRAGQRKLIGGQEDQ 326
V + +L G+R+L+GGQEDQ
Sbjct 311 VSTAQILLACGERRLVGGQEDQ 332
>gi|317124230|ref|YP_004098342.1| 4-hydroxy-2-oxovalerate aldolase [Intrasporangium calvum DSM
43043]
gi|315588318|gb|ADU47615.1| 4-hydroxy-2-oxovalerate aldolase [Intrasporangium calvum DSM
43043]
Length=386
Score = 425 bits (1093), Expect = 4e-117, Method: Compositional matrix adjust.
Identities = 206/332 (63%), Positives = 258/332 (78%), Gaps = 0/332 (0%)
Query 6 DVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFSKT 65
D+RITD++LRDGSH +HQFT+++V +V ALD AGV VIEV+HGDGLGGSSFNYGFSK
Sbjct 35 DLRITDSTLRDGSHAMQHQFTEEQVRGVVHALDQAGVQVIEVSHGDGLGGSSFNYGFSKV 94
Query 66 PEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVSIQHFG 125
E +LIK A A +A+IA LMLPG+GT +K A G S+ RIATHCTEADVS+QHF
Sbjct 95 DEFDLIKAAVDEATQAKIAILMLPGLGTVHHLKRAHAAGASVARIATHCTEADVSLQHFA 154
Query 126 LARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVSAL 185
AR+LG+ETVGFLM++H +PE LA QARIM DAG QCVYVVDSAGALVLD +R+ ++
Sbjct 155 AARDLGMETVGFLMLSHKASPEVLAQQARIMVDAGAQCVYVVDSAGALVLDTAQERIESV 214
Query 186 VAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEALIGVFD 245
+AE+G +AQVGFHGH+NL +G+ANSV A RAGAKQIDG+ GAGAGN+P E L ++
Sbjct 215 IAEIGAEAQVGFHGHQNLSMGIANSVLAYRAGAKQIDGALCALGAGAGNSPTEVLAATYE 274
Query 246 KIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQAERYGV 305
++G++TGID + AAEDVVRP +P +DR ++ GY+GVYSSFL HA R AERYGV
Sbjct 275 RLGIRTGIDLGQVLSAAEDVVRPFIPRLPWMDRASITQGYAGVYSSFLLHAERAAERYGV 334
Query 306 PASALLHRAGQRKLIGGQEDQLIDIALEIKRE 337
PA A+L R G+ +GGQED +IDIAL++ +E
Sbjct 335 PAHAILQRVGEAGYVGGQEDMIIDIALQLAQE 366
>gi|296141474|ref|YP_003648717.1| 4-hydroxy-2-oxovalerate aldolase [Tsukamurella paurometabola
DSM 20162]
gi|296029608|gb|ADG80378.1| 4-hydroxy-2-oxovalerate aldolase [Tsukamurella paurometabola
DSM 20162]
Length=349
Score = 425 bits (1092), Expect = 6e-117, Method: Compositional matrix adjust.
Identities = 216/338 (64%), Positives = 257/338 (77%), Gaps = 5/338 (1%)
Query 3 DMW-----DVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSS 57
D+W DVRI DTSLRDGSH HQFT+ V V ALD AGV +IEVTHGDGLGGS+
Sbjct 7 DLWNDPDRDVRIVDTSLRDGSHAMAHQFTEQNVRDTVRALDDAGVSLIEVTHGDGLGGST 66
Query 58 FNYGFSKTPEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEA 117
FNYGFS E++LI A A++A+IA LMLPG+GT +DI+ A D G RIATHCTEA
Sbjct 67 FNYGFSLVDERKLIAAAVDEAQQAKIAVLMLPGLGTVEDIRVAADLGAGALRIATHCTEA 126
Query 118 DVSIQHFGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDG 177
DVSIQHFG ARELGLETVGFLM++H APE LA QARIMADAGCQCVYVVDSAGAL+L+
Sbjct 127 DVSIQHFGAARELGLETVGFLMLSHMSAPEALAKQARIMADAGCQCVYVVDSAGALILED 186
Query 178 VADRVSALVAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPV 237
ADRV+ALVAELG DA VG+HGH+NL GVANSV A RAGAKQIDGS GAGAGN+P
Sbjct 187 AADRVAALVAELGADAHVGYHGHQNLSFGVANSVLAYRAGAKQIDGSLLALGAGAGNSPT 246
Query 238 EALIGVFDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAV 297
E L F+++GV+TG D + AAEDVV+P + ++DR++++ GY+GVYSSFL HA
Sbjct 247 EVLAATFERLGVRTGTDKDALMAAAEDVVKPYITRLPVMDRSSIVQGYAGVYSSFLLHAE 306
Query 298 RQAERYGVPASALLHRAGQRKLIGGQEDQLIDIALEIK 335
R A RYGVPA +L+ G+R +GGQED +I IA+E+
Sbjct 307 RAAARYGVPAHEILYECGRRGYVGGQEDMIIAIAVEMS 344
>gi|333918691|ref|YP_004492272.1| 4-hydroxy-2-oxovalerate aldolase [Amycolicicoccus subflavus DQS3-9A1]
gi|333480912|gb|AEF39472.1| 4-hydroxy-2-oxovalerate aldolase [Amycolicicoccus subflavus DQS3-9A1]
Length=349
Score = 424 bits (1091), Expect = 7e-117, Method: Compositional matrix adjust.
Identities = 210/343 (62%), Positives = 259/343 (76%), Gaps = 5/343 (1%)
Query 3 DMWD-----VRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSS 57
+ WD VRI DT+LRDGSH HQFT++ V VAALD GV +IEV HGDGLGGS+
Sbjct 2 NQWDGIDREVRIVDTTLRDGSHAMAHQFTEENVRNTVAALDQTGVSLIEVCHGDGLGGST 61
Query 58 FNYGFSKTPEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEA 117
FNYGFS E++LI A TA A+IA L+LPG+GT D++ A D G RIATHCTEA
Sbjct 62 FNYGFSLVDERKLISTAVETAHNAKIAVLLLPGLGTVADLRGAADLGAGAVRIATHCTEA 121
Query 118 DVSIQHFGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDG 177
DVS+QHF ARELGLETVGFLM++H + PE+LA Q RIM DAGCQCVYVVDSAGAL+L+
Sbjct 122 DVSVQHFSAARELGLETVGFLMLSHMVTPEQLAKQGRIMVDAGCQCVYVVDSAGALILED 181
Query 178 VADRVSALVAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPV 237
A+RV+ALVAE G DAQVG+HGH+NL GVANSV A RAGA+QIDGS GAGAGN+P
Sbjct 182 AAERVAALVAEFGGDAQVGYHGHQNLSFGVANSVLAYRAGARQIDGSLVALGAGAGNSPT 241
Query 238 EALIGVFDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAV 297
E L F+++G++TG+D + AAEDVV+P + ++DR++++ GY+GVYSSFL HA
Sbjct 242 EVLAATFERLGIRTGVDKDALMAAAEDVVKPFITRLPVMDRSSIVQGYAGVYSSFLLHAE 301
Query 298 RQAERYGVPASALLHRAGQRKLIGGQEDQLIDIALEIKRELDS 340
R AERYGVPA +L+R G+R +GGQED +I IALEI+ E D+
Sbjct 302 RAAERYGVPAHEILYRCGERGYVGGQEDMIISIALEIQAERDA 344
>gi|302527630|ref|ZP_07279972.1| 4-hydroxy-2-oxovalerate aldolase [Streptomyces sp. AA4]
gi|302436525|gb|EFL08341.1| 4-hydroxy-2-oxovalerate aldolase [Streptomyces sp. AA4]
Length=341
Score = 422 bits (1085), Expect = 4e-116, Method: Compositional matrix adjust.
Identities = 205/332 (62%), Positives = 260/332 (79%), Gaps = 0/332 (0%)
Query 6 DVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFSKT 65
DVR+ DT+LRDGSH HQFT+ +V V ALD AG+ +IEVTHGDGLGGS+FNYGFS
Sbjct 5 DVRLVDTTLRDGSHAMAHQFTEKQVRDTVRALDDAGISLIEVTHGDGLGGSTFNYGFSLV 64
Query 66 PEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVSIQHFG 125
E++LI A AK+A+IA L+LPG+GT D++ A D G RIATHCTEADVS+QHFG
Sbjct 65 DERKLIAAAVDEAKQAKIAVLLLPGLGTVTDLRAAADLGAGAVRIATHCTEADVSMQHFG 124
Query 126 LARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVSAL 185
AR+LGLETVGFLM++H +PE LA QARIM DAGCQCVYVVDSAGAL+LD +DRV+AL
Sbjct 125 AARDLGLETVGFLMLSHMSSPEDLAKQARIMVDAGCQCVYVVDSAGALILDDASDRVAAL 184
Query 186 VAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEALIGVFD 245
VAELG++AQVG+HGH+NL GVANSV A RAGA+QIDGS GAGAGN+P E L F+
Sbjct 185 VAELGDEAQVGYHGHQNLSFGVANSVLAYRAGARQIDGSLAALGAGAGNSPTEVLAATFE 244
Query 246 KIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQAERYGV 305
++G+KTG+D + +AAE+VV+ + ++DR+++I G++GVYSSFL HA R AERYGV
Sbjct 245 RLGIKTGVDKDVLLEAAENVVKKYLTRLPVMDRSSIIQGFAGVYSSFLLHAERAAERYGV 304
Query 306 PASALLHRAGQRKLIGGQEDQLIDIALEIKRE 337
PA +L++ G+ + +GGQED +IDIAL ++ E
Sbjct 305 PAHEILYKVGEERYVGGQEDMIIDIALRLRDE 336
>gi|269124801|ref|YP_003298171.1| 4-hydroxy-2-oxovalerate aldolase [Thermomonospora curvata DSM
43183]
gi|268309759|gb|ACY96133.1| 4-hydroxy-2-oxovalerate aldolase [Thermomonospora curvata DSM
43183]
Length=355
Score = 409 bits (1050), Expect = 5e-112, Method: Compositional matrix adjust.
Identities = 208/331 (63%), Positives = 249/331 (76%), Gaps = 0/331 (0%)
Query 7 VRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFSKTP 66
VRITD++LRDGSH HQFT+++V A V ALDAAGV VIEV+HGDGLGGSSFNYGFS
Sbjct 13 VRITDSTLRDGSHAMAHQFTEEQVRATVHALDAAGVEVIEVSHGDGLGGSSFNYGFSAVD 72
Query 67 EQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVSIQHFGL 126
E +L+ A A A+IA L+LPGVGT D+K A D G S+ RIATHCTEADVS QHF
Sbjct 73 EIDLVAAAVDEAVNAKIAVLLLPGVGTVRDLKRAHDAGASVARIATHCTEADVSCQHFAA 132
Query 127 ARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVSALV 186
ARELG+ETVGFLM+AH I PE+LA QARIM DAG QCVYVVDSAGALVL V RV ALV
Sbjct 133 ARELGMETVGFLMLAHRIGPEELARQARIMVDAGAQCVYVVDSAGALVLSDVQARVQALV 192
Query 187 AELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEALIGVFDK 246
E+G +AQVGFHGH+NL LGVANSV A + GA+QIDG+ GAGAGN+P E L F++
Sbjct 193 REIGHEAQVGFHGHQNLSLGVANSVLAYQNGARQIDGALCALGAGAGNSPTEILAATFER 252
Query 247 IGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQAERYGVP 306
+ ++TG++ AAE+VVRP +P DR A++ GY+GVYSSFL HA R AERYGVP
Sbjct 253 LNIETGVNVQAALAAAEEVVRPYLPRLPWADRAAIVQGYAGVYSSFLLHAERAAERYGVP 312
Query 307 ASALLHRAGQRKLIGGQEDQLIDIALEIKRE 337
A +L R G+ +GGQED +IDIA+++ E
Sbjct 313 AHEILQRVGEAGYVGGQEDMIIDIAVQLAEE 343
>gi|297154944|gb|ADI04656.1| 4-hydroxy-2-ketovalerate aldolase [Streptomyces bingchenggensis
BCW-1]
Length=362
Score = 408 bits (1048), Expect = 8e-112, Method: Compositional matrix adjust.
Identities = 204/337 (61%), Positives = 251/337 (75%), Gaps = 0/337 (0%)
Query 7 VRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFSKTP 66
+RITD++LRDGSH RHQFT+++V +V ALD AGV +IEV HGDGLGGSSFNYGFSK
Sbjct 24 LRITDSTLRDGSHAMRHQFTEEQVRGVVHALDKAGVEIIEVAHGDGLGGSSFNYGFSKVD 83
Query 67 EQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVSIQHFGL 126
E +LI A A A+IA LMLPGVGT ++K A G S+ RIATHCTEAD S+QHF
Sbjct 84 EIQLIGAAVDEATRAKIAVLMLPGVGTVTELKRAHAVGASVARIATHCTEADTSVQHFTA 143
Query 127 ARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVSALV 186
ARELG+ETVGFLM++H IAP++LA QARIM DAG QCVYVVDSAGALVL RV ALV
Sbjct 144 ARELGMETVGFLMLSHRIAPDELANQARIMVDAGAQCVYVVDSAGALVLTDAQARVQALV 203
Query 187 AELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEALIGVFDK 246
E+G +AQVGFHGH+NL LGVANSV A + GA+QIDG+ GAGAGN+P E L F++
Sbjct 204 NEIGHEAQVGFHGHQNLSLGVANSVLAYQGGAQQIDGALCALGAGAGNSPTEVLAATFER 263
Query 247 IGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQAERYGVP 306
+G+ TG+D AA+DVV+P +P +DR++++ GY+GVYSSFL HA R AERYGVP
Sbjct 264 MGIPTGVDVDLALAAAQDVVKPFIPRLPWMDRSSIVQGYAGVYSSFLLHAERAAERYGVP 323
Query 307 ASALLHRAGQRKLIGGQEDQLIDIALEIKRELDSGAA 343
A +L + G+ +GGQED +IDIAL + E + A
Sbjct 324 AHEILEQVGEAGYVGGQEDMIIDIALRLAEEREKAGA 360
>gi|258654204|ref|YP_003203360.1| 4-hydroxy-2-ketovalerate aldolase [Nakamurella multipartita DSM
44233]
gi|258557429|gb|ACV80371.1| 4-hydroxy-2-oxovalerate aldolase [Nakamurella multipartita DSM
44233]
Length=352
Score = 402 bits (1033), Expect = 4e-110, Method: Compositional matrix adjust.
Identities = 202/331 (62%), Positives = 248/331 (75%), Gaps = 0/331 (0%)
Query 2 TDMWDVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYG 61
+D VR+TD++LRDGSH RHQFT D V +V ALDAAGV VIEVTHGDGL GSSFNYG
Sbjct 14 SDRPFVRLTDSTLRDGSHAVRHQFTTDNVTDVVTALDAAGVSVIEVTHGDGLAGSSFNYG 73
Query 62 FSKTPEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVSI 121
F K + EL+ A A A+IA L+LPG+GT D+K+ G I R+ATHCTEADVS+
Sbjct 74 FGKHTDAELVAAAVRAATRAKIAVLVLPGLGTVHDLKQVHSAGAQIARVATHCTEADVSV 133
Query 122 QHFGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADR 181
+HF ARELG+ETVGFLM++H I PE+LA QARIMADAGCQCVYVVDSAGAL+ D V DR
Sbjct 134 EHFTAARELGMETVGFLMLSHRIGPEQLAKQARIMADAGCQCVYVVDSAGALLPDMVRDR 193
Query 182 VSALVAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEALI 241
V ALVAELG+DAQVGFHGH+NL LGVANS+ A GA+QIDG+ GAGAGN+P E L
Sbjct 194 VQALVAELGDDAQVGFHGHQNLSLGVANSIVAYENGARQIDGTLCALGAGAGNSPTEILA 253
Query 242 GVFDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQAE 301
VFD +GV TG+D + DAAED+V+P + + DR +++ G GVY+SFL HA R A+
Sbjct 254 TVFDVMGVPTGVDAAKVLDAAEDIVKPMITRMPVADRASIVQGRYGVYNSFLLHAERAAD 313
Query 302 RYGVPASALLHRAGQRKLIGGQEDQLIDIAL 332
RYGV + +L + G+ +GGQED +ID+A+
Sbjct 314 RYGVSSHEILRKVGEAGYVGGQEDMIIDVAI 344
>gi|300786106|ref|YP_003766397.1| 4-hydroxy-2-ketovalerate aldolase [Amycolatopsis mediterranei
U32]
gi|299795620|gb|ADJ45995.1| 4-hydroxy-2-ketovalerate aldolase [Amycolatopsis mediterranei
U32]
gi|340527574|gb|AEK42779.1| 4-hyroxy-2-oxovalerate/4-hydroxy-2-oxopentanoic acid aldolase
[Amycolatopsis mediterranei S699]
Length=351
Score = 402 bits (1032), Expect = 6e-110, Method: Compositional matrix adjust.
Identities = 202/332 (61%), Positives = 245/332 (74%), Gaps = 0/332 (0%)
Query 6 DVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFSKT 65
DVRI DT+LRDGSH H+FT+ +V V ALD AGV VIEVTHGDGLGGSSF YGFS
Sbjct 19 DVRIIDTTLRDGSHAMAHRFTEQQVRDTVRALDRAGVGVIEVTHGDGLGGSSFTYGFSAV 78
Query 66 PEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVSIQHFG 125
E ELI A AK+A+IA L++PG+GT +D++ A D G + R+ATHCTEADVS QHFG
Sbjct 79 DELELIAAAREEAKQAKIAVLLVPGIGTAEDLQRAFDAGAEMVRVATHCTEADVSPQHFG 138
Query 126 LARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVSAL 185
LARELG+ET GFLMMAH PE LA QARIM DAGCQ YV DSAGAL++ R AL
Sbjct 139 LARELGMETAGFLMMAHRTPPEDLAKQARIMVDAGCQATYVTDSAGALLMHEARARFEAL 198
Query 186 VAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEALIGVFD 245
VAE+G+ A VG+HGH+NL LGVANSV A AG + IDGS GAGAGN+P E L VFD
Sbjct 199 VAEVGDTAWVGYHGHQNLSLGVANSVLAYEAGVRYIDGSLCALGAGAGNSPTEVLAAVFD 258
Query 246 KIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQAERYGV 305
++ + TG+D + DAAE+VVRP + +DRNA++ G++GVYSSFL HA R AERYGV
Sbjct 259 RLEIDTGLDVGALLDAAEEVVRPYLHRWPKMDRNAIVQGWAGVYSSFLLHAERAAERYGV 318
Query 306 PASALLHRAGQRKLIGGQEDQLIDIALEIKRE 337
PA A+L R G+ L+GGQED +ID+A+++ E
Sbjct 319 PAQAILRRCGELALVGGQEDMIIDVAVQLAAE 350
>gi|111025801|ref|YP_708221.1| 4-hydroxy-2-ketovalerate aldolase [Rhodococcus jostii RHA1]
gi|123143845|sp|Q0RXC3.1|HOA6_RHOSR RecName: Full=4-hydroxy-2-oxovalerate aldolase 6; Short=HOA 6;
AltName: Full=4-hydroxy-2-keto-pentanoic acid aldolase 6;
AltName: Full=4-hydroxy-2-oxopentanoate aldolase 6
gi|110824780|gb|ABH00063.1| 4-hydroxy-2-oxovalerate aldolase [Rhodococcus jostii RHA1]
Length=354
Score = 399 bits (1024), Expect = 5e-109, Method: Compositional matrix adjust.
Identities = 190/331 (58%), Positives = 246/331 (75%), Gaps = 0/331 (0%)
Query 6 DVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFSKT 65
DVRI DT+LRDGSH + HQFT+ +V V ALD AGV VIEVTHGDGLGGS+FNYGFS+
Sbjct 9 DVRIVDTTLRDGSHAQSHQFTESQVRDTVRALDGAGVEVIEVTHGDGLGGSTFNYGFSRI 68
Query 66 PEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVSIQHFG 125
+ EL+++AA TA++A+IA L++PG+GT DD+++A D G + RIATHCTEADVS+QHF
Sbjct 69 SDLELVQVAADTAEQAKIAVLLVPGIGTADDLRKAADRGAEVVRIATHCTEADVSLQHFE 128
Query 126 LARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVSAL 185
+AR+LG++T GFLMMAH PE+LA QAR+M DAGCQ YV DSAGAL++ DR AL
Sbjct 129 IARDLGMQTCGFLMMAHRTTPEELARQARLMVDAGCQVPYVTDSAGALLMHEAKDRFDAL 188
Query 186 VAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEALIGVFD 245
+ E+G+DA VG+HGH+N+ LGVANSV A AG + IDGS GAGAGN+P E L +FD
Sbjct 189 ITEVGDDAWVGYHGHQNMSLGVANSVIAYEAGVRYIDGSLCALGAGAGNSPTELLAAIFD 248
Query 246 KIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQAERYGV 305
++ + TG+D DAAE VVRP + +DRNA++ G+ GVYSSFL HA RYGV
Sbjct 249 RMNIATGLDVMATLDAAETVVRPYLNRWPKIDRNAIVQGWVGVYSSFLLHAETAGARYGV 308
Query 306 PASALLHRAGQRKLIGGQEDQLIDIALEIKR 336
P +L R G+ +GGQED +ID+A+++ +
Sbjct 309 PVHEILRRCGELGYVGGQEDMIIDVAIQLAK 339
>gi|302546957|ref|ZP_07299299.1| 4-hydroxy-2-oxovalerate aldolase [Streptomyces hygroscopicus
ATCC 53653]
gi|302464575|gb|EFL27668.1| 4-hydroxy-2-oxovalerate aldolase [Streptomyces himastatinicus
ATCC 53653]
Length=343
Score = 397 bits (1021), Expect = 1e-108, Method: Compositional matrix adjust.
Identities = 201/332 (61%), Positives = 244/332 (74%), Gaps = 0/332 (0%)
Query 6 DVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFSKT 65
DVRI DT+LRDGSH H+FT+ +V V ALDAAGV IEV+HGDG+GGSSFNYGFS T
Sbjct 9 DVRIIDTTLRDGSHAVAHRFTETQVRDTVRALDAAGVEWIEVSHGDGVGGSSFNYGFSGT 68
Query 66 PEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVSIQHFG 125
E LI A A+ A+IA L++PG+GT DD+K A D G + R+ATHCTEADVS QHF
Sbjct 69 DEMSLINAAREEARRAKIAVLLVPGIGTVDDLKRAHDAGAEMVRVATHCTEADVSPQHFA 128
Query 126 LARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVSAL 185
+ARELG+ET GFLMMAH PE LA QARIM DAGCQ YV DSAGAL++ R AL
Sbjct 129 VARELGMETAGFLMMAHKTDPENLAKQARIMVDAGCQAPYVTDSAGALLMGDARARFEAL 188
Query 186 VAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEALIGVFD 245
VAE+G++A VG+HGH+N+ LGVANSV A AG + IDGS GAGAGN+P E L VFD
Sbjct 189 VAEVGDEAWVGYHGHQNMSLGVANSVIAHEAGVRYIDGSLCALGAGAGNSPTEVLGAVFD 248
Query 246 KIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQAERYGV 305
++GV TG+D + DAAE+VVRP + +DRNA++ G++GVYSSFL HA R AERY V
Sbjct 249 RLGVATGLDAGLLLDAAEEVVRPYLSRWPKMDRNAIVQGWAGVYSSFLLHAERAAERYKV 308
Query 306 PASALLHRAGQRKLIGGQEDQLIDIALEIKRE 337
PA A+L R G+R +GGQED +IDIA+ + E
Sbjct 309 PAHAILRRCGERGYVGGQEDMIIDIAIGLAEE 340
>gi|331697956|ref|YP_004334195.1| 4-hydroxy-2-oxovalerate aldolase [Pseudonocardia dioxanivorans
CB1190]
gi|326952645|gb|AEA26342.1| 4-hydroxy-2-oxovalerate aldolase [Pseudonocardia dioxanivorans
CB1190]
Length=344
Score = 381 bits (978), Expect = 1e-103, Method: Compositional matrix adjust.
Identities = 195/332 (59%), Positives = 241/332 (73%), Gaps = 0/332 (0%)
Query 6 DVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFSKT 65
DVRI DT+LRDGSH H+FT+ +V V ALD AGV IEV+HGDG+GGSSFNYGFS T
Sbjct 9 DVRIIDTTLRDGSHAMAHRFTETQVRDTVRALDGAGVEWIEVSHGDGVGGSSFNYGFSGT 68
Query 66 PEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVSIQHFG 125
E LI A A++ARIA L++PG+GT DD+K A D G + R+ATHCTEADVS QHF
Sbjct 69 DEMTLIAAAREEARQARIAVLLVPGIGTVDDLKRAHDAGAEMVRVATHCTEADVSPQHFA 128
Query 126 LARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVSAL 185
AR+LG+ETVGFLMMAH P LA QARIM DAGC+C YV DSAGAL++ R AL
Sbjct 129 AARDLGMETVGFLMMAHRTDPADLAKQARIMVDAGCECPYVTDSAGALLMHEARARFEAL 188
Query 186 VAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEALIGVFD 245
+AE+G++A VG+HGH+NL +GVANSV A G + IDGS GAG+GN+P E L VFD
Sbjct 189 LAEVGDEALVGYHGHQNLSMGVANSVIAYETGVRSIDGSLCALGAGSGNSPTEVLAAVFD 248
Query 246 KIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQAERYGV 305
++GV TG+D + DAAEDVVRP + +DRNA++ G++GVYSSFL HA R AERY V
Sbjct 249 RLGVDTGLDAGALLDAAEDVVRPYLQRWPKMDRNAIVQGWAGVYSSFLLHAERAAERYKV 308
Query 306 PASALLHRAGQRKLIGGQEDQLIDIALEIKRE 337
PA +L R G+ +GGQED +ID+A+ + E
Sbjct 309 PAHEILRRCGELGYVGGQEDMIIDVAIGLAAE 340
>gi|296119335|ref|ZP_06837903.1| 4-hydroxy-2-oxovalerate aldolase [Corynebacterium ammoniagenes
DSM 20306]
gi|295967727|gb|EFG80984.1| 4-hydroxy-2-oxovalerate aldolase [Corynebacterium ammoniagenes
DSM 20306]
Length=337
Score = 379 bits (974), Expect = 3e-103, Method: Compositional matrix adjust.
Identities = 188/333 (57%), Positives = 244/333 (74%), Gaps = 1/333 (0%)
Query 4 MWDVRITDTSLRDGSHHKRHQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFS 63
M +R+ DT+LRDGSH RHQ+T+ +V +V ALD A + +IEVTHGDGLGGSSFNYGFS
Sbjct 1 MTKIRLNDTTLRDGSHSVRHQYTEQQVRQVVRALDDANIEMIEVTHGDGLGGSSFNYGFS 60
Query 64 KTPEQELIKLAAATAKEARIAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVSIQH 123
+ + +LI+ AA AK A+IA L+LPG+GT D+KEA G + RIATHCTEADVSIQH
Sbjct 61 QVSDLDLIESAADEAKNAKIAALLLPGLGTIHDLKEAHARGAKMVRIATHCTEADVSIQH 120
Query 124 FGLARELGLETVGFLMMAHTIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVS 183
F ARELG+ET GFLM++H +P +LA QA IM DAGCQCV VVDSAGAL+++ DRV+
Sbjct 121 FQAARELGMETAGFLMLSHRSSPAELAQQASIMVDAGCQCVSVVDSAGALIMNEAKDRVA 180
Query 184 ALVAELGEDAQVGFHGHENLGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEALIGV 243
AL +G+ AQVGFHGH+N+ GVANSV AV AGA QIDGS GAGAGN P E
Sbjct 181 ALYDAIGDRAQVGFHGHQNMSFGVANSVLAVEAGASQIDGSLAGLGAGAGNTPTEVAAIA 240
Query 244 FDKIGVKTGIDFFDIADAAEDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQAERY 303
F+++G++TG+D I DAA D+++ + +DR +++ G GVY+SFL HA R AERY
Sbjct 241 FERLGIETGVDTKKILDAA-DLLKGMVNRLPSMDRGSIVQGQMGVYNSFLLHAERAAERY 299
Query 304 GVPASALLHRAGQRKLIGGQEDQLIDIALEIKR 336
+PA +L G+R +GGQED +I++AL++K+
Sbjct 300 DIPAPEILAEVGRRGYVGGQEDMIIEVALDLKK 332
>gi|288921462|ref|ZP_06415739.1| 4-hydroxy-2-oxovalerate aldolase [Frankia sp. EUN1f]
gi|288347140|gb|EFC81440.1| 4-hydroxy-2-oxovalerate aldolase [Frankia sp. EUN1f]
Length=336
Score = 379 bits (972), Expect = 5e-103, Method: Compositional matrix adjust.
Identities = 193/312 (62%), Positives = 232/312 (75%), Gaps = 0/312 (0%)
Query 23 HQFTKDEVGAIVAALDAAGVPVIEVTHGDGLGGSSFNYGFSKTPEQELIKLAAATAKEAR 82
HQFT+ +V V ALD AGV VIEV HGDGLGGS+FNYGFS E L++ AA A A+
Sbjct 3 HQFTQAQVRDTVRALDRAGVAVIEVAHGDGLGGSTFNYGFSLVDELTLVEAAAEEATAAK 62
Query 83 IAFLMLPGVGTKDDIKEARDNGGSICRIATHCTEADVSIQHFGLARELGLETVGFLMMAH 142
IA L+LPGVGT ++ ARD G ++ R+ATHCTEADVSIQHF ARE+GLETVGFLM++H
Sbjct 63 IAVLLLPGVGTIASMRAARDAGATVVRVATHCTEADVSIQHFAAAREMGLETVGFLMLSH 122
Query 143 TIAPEKLAAQARIMADAGCQCVYVVDSAGALVLDGVADRVSALVAELGEDAQVGFHGHEN 202
I P +LAAQARIM DAGCQCVYVVDSAGAL+L+ DRV+ALV E+G DAQVG+HGH+N
Sbjct 123 RIGPRRLAAQARIMVDAGCQCVYVVDSAGALILEDAGDRVAALVDEIGADAQVGYHGHQN 182
Query 203 LGLGVANSVAAVRAGAKQIDGSCRRFGAGAGNAPVEALIGVFDKIGVKTGIDFFDIADAA 262
L GVANSV A RAGA+QIDGS GAGAGNAP E L+ FD++GV TGID I AA
Sbjct 183 LAFGVANSVLAYRAGARQIDGSLCALGAGAGNAPTEVLVAAFDRLGVSTGIDVDTILAAA 242
Query 263 EDVVRPAMPAECLLDRNALIMGYSGVYSSFLKHAVRQAERYGVPASALLHRAGQRKLIGG 322
+ V P + +DR +++ G++GVYSSFL HA R A RYGVPA +L G+ +GG
Sbjct 243 QTVALPYITRLPWMDRGSIVQGHAGVYSSFLLHAERAATRYGVPAHEILREVGRAGYVGG 302
Query 323 QEDQLIDIALEI 334
QED +IDIAL +
Sbjct 303 QEDMIIDIALRL 314
Lambda K H
0.320 0.136 0.393
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 636071322808
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
Posted date: Sep 5, 2011 4:36 AM
Number of letters in database: 5,219,829,388
Number of sequences in database: 15,229,318
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40