BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv3549c Length=259 Score E Sequences producing significant alignments: (Bits) Value gi|15610685|ref|NP_218066.1| short chain dehydrogenase [Mycobact... 520 1e-145 gi|118619295|ref|YP_907627.1| short chain dehydrogenase [Mycobac... 455 3e-126 gi|240169756|ref|ZP_04748415.1| short chain dehydrogenase [Mycob... 454 5e-126 gi|183985005|ref|YP_001853296.1| short-chain type dehydrogenase/... 454 6e-126 gi|342862377|ref|ZP_08719017.1| short chain dehydrogenase [Mycob... 383 2e-104 gi|315446175|ref|YP_004079054.1| hypothetical protein Mspyr1_467... 382 2e-104 gi|41406615|ref|NP_959451.1| short chain dehydrogenase [Mycobact... 380 1e-103 gi|108801645|ref|YP_641842.1| short chain dehydrogenase [Mycobac... 376 1e-102 gi|126437631|ref|YP_001073322.1| short chain dehydrogenase [Myco... 375 3e-102 gi|254822632|ref|ZP_05227633.1| short chain dehydrogenase [Mycob... 373 1e-101 gi|118468241|ref|YP_890226.1| short chain dehydrogenase [Mycobac... 371 7e-101 gi|296166581|ref|ZP_06849011.1| 3-oxoacyl-[acyl-carrier-protein]... 370 9e-101 gi|333992343|ref|YP_004524957.1| short-chain dehydrogenase [Myco... 370 1e-100 gi|120406213|ref|YP_956042.1| short chain dehydrogenase [Mycobac... 366 2e-99 gi|118465785|ref|YP_879891.1| short chain dehydrogenase [Mycobac... 364 8e-99 gi|145222083|ref|YP_001132761.1| short chain dehydrogenase [Myco... 352 3e-95 gi|169627710|ref|YP_001701359.1| short chain dehydrogenase [Myco... 349 2e-94 gi|226364161|ref|YP_002781943.1| short chain dehydrogenase [Rhod... 323 2e-86 gi|319947734|ref|ZP_08021940.1| short chain dehydrogenase [Dietz... 323 2e-86 gi|333918630|ref|YP_004492211.1| putative oxidoreductase [Amycol... 320 9e-86 gi|111021625|ref|YP_704597.1| short chain dehydrogenase [Rhodoco... 318 4e-85 gi|325674910|ref|ZP_08154597.1| trans-2-enoyl-CoA reductase (NAD... 311 6e-83 gi|312138185|ref|YP_004005521.1| short chain dehydrogenase [Rhod... 309 3e-82 gi|54022478|ref|YP_116720.1| short chain dehydrogenase [Nocardia... 306 3e-81 gi|326383134|ref|ZP_08204823.1| short chain dehydrogenase [Gordo... 303 1e-80 gi|296141496|ref|YP_003648739.1| short-chain dehydrogenase/reduc... 295 4e-78 gi|343928255|ref|ZP_08767709.1| putative oxidoreductase [Gordoni... 293 2e-77 gi|262203839|ref|YP_003275047.1| short-chain dehydrogenase/reduc... 281 7e-74 gi|119716967|ref|YP_923932.1| short chain dehydrogenase [Nocardi... 280 1e-73 gi|300785272|ref|YP_003765563.1| short-chain dehydrogenase [Amyc... 280 2e-73 gi|337769602|emb|CCB78315.1| Short chain dehydrogenase [Streptom... 279 4e-73 gi|345011667|ref|YP_004814021.1| short-chain dehydrogenase/reduc... 270 1e-70 gi|297198991|ref|ZP_06916388.1| 2-hydroxycyclohexanecarboxyl-CoA... 266 2e-69 gi|311744252|ref|ZP_07718056.1| trans-2-enoyl-CoA reductase (NAD... 266 3e-69 gi|328881704|emb|CCA54943.1| Probable short-chain type dehydroge... 265 4e-69 gi|302533873|ref|ZP_07286215.1| 3-oxoacyl-[acyl-carrier-protein]... 260 1e-67 gi|302548221|ref|ZP_07300563.1| short-chain dehydrogenase/reduct... 258 5e-67 gi|294812052|ref|ZP_06770695.1| Short chain dehydrogenase [Strep... 253 2e-65 gi|254393737|ref|ZP_05008858.1| short chain dehydrogenase [Strep... 253 3e-65 gi|297155139|gb|ADI04851.1| short chain dehydrogenase [Streptomy... 252 4e-65 gi|290961228|ref|YP_003492410.1| dehydrogenase [Streptomyces sca... 248 8e-64 gi|302528346|ref|ZP_07280688.1| 2-hydroxycyclohexanecarboxyl-CoA... 246 3e-63 gi|302549254|ref|ZP_07301596.1| 2-hydroxycyclohexanecarboxyl-CoA... 245 4e-63 gi|254481390|ref|ZP_05094635.1| oxidoreductase, short chain dehy... 240 1e-61 gi|77359832|ref|YP_339407.1| short chain dehydrogenase [Pseudoal... 240 1e-61 gi|271963598|ref|YP_003337794.1| short chain dehydrogenase [Stre... 239 3e-61 gi|29832746|ref|NP_827380.1| short chain dehydrogenase [Streptom... 238 8e-61 gi|254387109|ref|ZP_05002382.1| short chain dehydrogenase [Strep... 236 3e-60 gi|256390586|ref|YP_003112150.1| short chain dehydrogenase [Cate... 234 7e-60 gi|339321863|ref|YP_004680757.1| 2,6-dioxo-6-phenylhexa-3-enoate... 232 5e-59 >gi|15610685|ref|NP_218066.1| short chain dehydrogenase [Mycobacterium tuberculosis H37Rv] gi|15843161|ref|NP_338198.1| short chain dehydrogenase [Mycobacterium tuberculosis CDC1551] gi|31794725|ref|NP_857218.1| short chain dehydrogenase [Mycobacterium bovis AF2122/97] 78 more sequence titles Length=259 Score = 520 bits (1338), Expect = 1e-145, Method: Compositional matrix adjust. Identities = 258/259 (99%), Positives = 259/259 (100%), Gaps = 0/259 (0%) Query 1 VTLAEAADAINFGLAGRVVLVTGGVRGVGAGISSVFAEQGATVITCARRAVDGQPYEFHR 60 +TLAEAADAINFGLAGRVVLVTGGVRGVGAGISSVFAEQGATVITCARRAVDGQPYEFHR Sbjct 1 MTLAEAADAINFGLAGRVVLVTGGVRGVGAGISSVFAEQGATVITCARRAVDGQPYEFHR 60 Query 61 CDIRDEDSVKRLVGEIGERHGRLDMLVNNAGGSPYALAAEATHNFHRKIVELNVLAPLLV 120 CDIRDEDSVKRLVGEIGERHGRLDMLVNNAGGSPYALAAEATHNFHRKIVELNVLAPLLV Sbjct 61 CDIRDEDSVKRLVGEIGERHGRLDMLVNNAGGSPYALAAEATHNFHRKIVELNVLAPLLV 120 Query 121 SQHANVLMQAQPNGGSIVNICSVSGRRPTPGTAAYGAAKAGLENLTTTLAVEWAPKVRVN 180 SQHANVLMQAQPNGGSIVNICSVSGRRPTPGTAAYGAAKAGLENLTTTLAVEWAPKVRVN Sbjct 121 SQHANVLMQAQPNGGSIVNICSVSGRRPTPGTAAYGAAKAGLENLTTTLAVEWAPKVRVN 180 Query 181 AVVVGMVETERSELFYGDAESIARVAATVPLGRLARPADIGWAAAFLASDAASYISGATL 240 AVVVGMVETERSELFYGDAESIARVAATVPLGRLARPADIGWAAAFLASDAASYISGATL Sbjct 181 AVVVGMVETERSELFYGDAESIARVAATVPLGRLARPADIGWAAAFLASDAASYISGATL 240 Query 241 EVHGGGEPPPYLGASSANK 259 EVHGGGEPPPYLGASSANK Sbjct 241 EVHGGGEPPPYLGASSANK 259 >gi|118619295|ref|YP_907627.1| short chain dehydrogenase [Mycobacterium ulcerans Agy99] gi|118571405|gb|ABL06156.1| short-chain type dehydrogenase/reductase [Mycobacterium ulcerans Agy99] Length=259 Score = 455 bits (1170), Expect = 3e-126, Method: Compositional matrix adjust. Identities = 226/259 (88%), Positives = 239/259 (93%), Gaps = 0/259 (0%) Query 1 VTLAEAADAINFGLAGRVVLVTGGVRGVGAGISSVFAEQGATVITCARRAVDGQPYEFHR 60 +T AEAA AIN GL GRVVLVTGGVRGVGAGISSVFAEQGATVITCARRAV+ P+EFH Sbjct 1 MTRAEAAQAINLGLVGRVVLVTGGVRGVGAGISSVFAEQGATVITCARRAVENSPHEFHC 60 Query 61 CDIRDEDSVKRLVGEIGERHGRLDMLVNNAGGSPYALAAEATHNFHRKIVELNVLAPLLV 120 CDIRDEDSVKRL+G I ERHGRLD+LVNNAGGSPYALAAEAT FH KIVELN+LAPLLV Sbjct 61 CDIRDEDSVKRLMGSIAERHGRLDVLVNNAGGSPYALAAEATPRFHSKIVELNLLAPLLV 120 Query 121 SQHANVLMQAQPNGGSIVNICSVSGRRPTPGTAAYGAAKAGLENLTTTLAVEWAPKVRVN 180 SQHA LMQ QP GGSIVN+CSVSGRRPTPGTAAYGAAKAG E+LT+TLAVEWAPK+RVN Sbjct 121 SQHAYGLMQEQPTGGSIVNVCSVSGRRPTPGTAAYGAAKAGFESLTSTLAVEWAPKIRVN 180 Query 181 AVVVGMVETERSELFYGDAESIARVAATVPLGRLARPADIGWAAAFLASDAASYISGATL 240 A+VVGMV TE+SELFYGDAESIARVAATVPLGRLA+PADIGWAAAFLASD ASYISGATL Sbjct 181 ALVVGMVATEQSELFYGDAESIARVAATVPLGRLAQPADIGWAAAFLASDLASYISGATL 240 Query 241 EVHGGGEPPPYLGASSANK 259 EVHGGGEPPPYL ASSANK Sbjct 241 EVHGGGEPPPYLAASSANK 259 >gi|240169756|ref|ZP_04748415.1| short chain dehydrogenase [Mycobacterium kansasii ATCC 12478] Length=263 Score = 454 bits (1169), Expect = 5e-126, Method: Compositional matrix adjust. Identities = 223/254 (88%), Positives = 235/254 (93%), Gaps = 0/254 (0%) Query 6 AADAINFGLAGRVVLVTGGVRGVGAGISSVFAEQGATVITCARRAVDGQPYEFHRCDIRD 65 A +A+N GLAGRVVLVTGGVRGVGAGIS+VFAEQGATVITCARR V+G PYEFH CDIRD Sbjct 10 AGEAVNLGLAGRVVLVTGGVRGVGAGISAVFAEQGATVITCARRVVEGLPYEFHACDIRD 69 Query 66 EDSVKRLVGEIGERHGRLDMLVNNAGGSPYALAAEATHNFHRKIVELNVLAPLLVSQHAN 125 EDSV R++G I ERHGRLD+LVNNAGGSPYALAAEATHNFHRKIVELNVLAPLLVSQ AN Sbjct 70 EDSVGRMMGAIAERHGRLDVLVNNAGGSPYALAAEATHNFHRKIVELNVLAPLLVSQQAN 129 Query 126 VLMQAQPNGGSIVNICSVSGRRPTPGTAAYGAAKAGLENLTTTLAVEWAPKVRVNAVVVG 185 LMQ Q GGSIVNICSVSGRRPTPGTAAYGAAKAGLENLT TLAVEWAP+VRVNAVVVG Sbjct 130 ALMQEQERGGSIVNICSVSGRRPTPGTAAYGAAKAGLENLTATLAVEWAPQVRVNAVVVG 189 Query 186 MVETERSELFYGDAESIARVAATVPLGRLARPADIGWAAAFLASDAASYISGATLEVHGG 245 MVETE+S LFYGDAES+ARVAATVPLGRLA+P D+GWAAAFL SD ASYISGATLEVHGG Sbjct 190 MVETEQSGLFYGDAESVARVAATVPLGRLAKPTDVGWAAAFLTSDVASYISGATLEVHGG 249 Query 246 GEPPPYLGASSANK 259 GEPPPYL ASSANK Sbjct 250 GEPPPYLAASSANK 263 >gi|183985005|ref|YP_001853296.1| short-chain type dehydrogenase/reductase [Mycobacterium marinum M] gi|183178331|gb|ACC43441.1| short-chain type dehydrogenase/reductase [Mycobacterium marinum M] Length=259 Score = 454 bits (1168), Expect = 6e-126, Method: Compositional matrix adjust. Identities = 226/259 (88%), Positives = 239/259 (93%), Gaps = 0/259 (0%) Query 1 VTLAEAADAINFGLAGRVVLVTGGVRGVGAGISSVFAEQGATVITCARRAVDGQPYEFHR 60 +T A AA AIN GLAGRVVLVTGGVRGVGAGISSVFAEQGATVITCARRAV+ P+EFH Sbjct 1 MTRAAAAQAINLGLAGRVVLVTGGVRGVGAGISSVFAEQGATVITCARRAVENSPHEFHC 60 Query 61 CDIRDEDSVKRLVGEIGERHGRLDMLVNNAGGSPYALAAEATHNFHRKIVELNVLAPLLV 120 CDIRDEDSVKRL+G I ERHGRLD+LVNNAGGSPYALAAEAT FH KIVELN+LAPLLV Sbjct 61 CDIRDEDSVKRLMGSIAERHGRLDVLVNNAGGSPYALAAEATPRFHSKIVELNLLAPLLV 120 Query 121 SQHANVLMQAQPNGGSIVNICSVSGRRPTPGTAAYGAAKAGLENLTTTLAVEWAPKVRVN 180 SQHA LMQ QP GGSIVN+CSVSGRRPTPGTAAYGAAKAG E+LT+TLAVEWAPK+RVN Sbjct 121 SQHAYGLMQEQPTGGSIVNVCSVSGRRPTPGTAAYGAAKAGFESLTSTLAVEWAPKIRVN 180 Query 181 AVVVGMVETERSELFYGDAESIARVAATVPLGRLARPADIGWAAAFLASDAASYISGATL 240 A+VVGMV TE+SELFYGDAESIARVAATVPLGRLA+PADIGWAAAFLASD ASYISGATL Sbjct 181 ALVVGMVATEQSELFYGDAESIARVAATVPLGRLAQPADIGWAAAFLASDLASYISGATL 240 Query 241 EVHGGGEPPPYLGASSANK 259 EVHGGGEPPPYL ASSANK Sbjct 241 EVHGGGEPPPYLAASSANK 259 >gi|342862377|ref|ZP_08719017.1| short chain dehydrogenase [Mycobacterium colombiense CECT 3035] gi|342130048|gb|EGT83382.1| short chain dehydrogenase [Mycobacterium colombiense CECT 3035] Length=244 Score = 383 bits (983), Expect = 2e-104, Method: Compositional matrix adjust. Identities = 185/241 (77%), Positives = 211/241 (88%), Gaps = 0/241 (0%) Query 18 VVLVTGGVRGVGAGISSVFAEQGATVITCARRAVDGQPYEFHRCDIRDEDSVKRLVGEIG 77 +VLVTGGVRGVGAGISSVFA QGATV+TCARRAVDG PYEFH CD+RD+D+VK LV I Sbjct 1 MVLVTGGVRGVGAGISSVFAGQGATVVTCARRAVDGSPYEFHSCDVRDDDAVKGLVDTIV 60 Query 78 ERHGRLDMLVNNAGGSPYALAAEATHNFHRKIVELNVLAPLLVSQHANVLMQAQPNGGSI 137 +RHGRLD++VNNAGGSPY L AE++ F+RKI+ELN+L L VSQHAN MQ QP GGSI Sbjct 61 DRHGRLDVVVNNAGGSPYVLTAESSAKFNRKIIELNLLGALSVSQHANDHMQTQPQGGSI 120 Query 138 VNICSVSGRRPTPGTAAYGAAKAGLENLTTTLAVEWAPKVRVNAVVVGMVETERSELFYG 197 VNICS+SGRRP+PGT AYGAAKAGLE+LT TLAVEW PKVRVNA VVGMVETE+SELFYG Sbjct 121 VNICSLSGRRPSPGTGAYGAAKAGLESLTQTLAVEWGPKVRVNACVVGMVETEQSELFYG 180 Query 198 DAESIARVAATVPLGRLARPADIGWAAAFLASDAASYISGATLEVHGGGEPPPYLGASSA 257 DA+SIA ++ VPLGRLA PADIGWAAAFLAS+ A+YISGA+LEVHGGGEPP YL ++A Sbjct 181 DADSIAAISKNVPLGRLADPADIGWAAAFLASNLAAYISGASLEVHGGGEPPHYLATTNA 240 Query 258 N 258 + Sbjct 241 S 241 >gi|315446175|ref|YP_004079054.1| hypothetical protein Mspyr1_46760 [Mycobacterium sp. Spyr1] gi|315264478|gb|ADU01220.1| dehydrogenase of unknown specificity, short-chain alcohol dehydrogenase like protein [Mycobacterium sp. Spyr1] Length=265 Score = 382 bits (982), Expect = 2e-104, Method: Compositional matrix adjust. Identities = 188/250 (76%), Positives = 212/250 (85%), Gaps = 0/250 (0%) Query 9 AINFGLAGRVVLVTGGVRGVGAGISSVFAEQGATVITCARRAVDGQPYEFHRCDIRDEDS 68 AI GL GRVVLVTGGVRGVGAGIS+VFA+QGATVITCARR V+ PYEF CDIRD+D+ Sbjct 14 AIALGLTGRVVLVTGGVRGVGAGISTVFADQGATVITCARRPVESSPYEFRACDIRDDDA 73 Query 69 VKRLVGEIGERHGRLDMLVNNAGGSPYALAAEATHNFHRKIVELNVLAPLLVSQHANVLM 128 VK LV I HGRLD++VNNAGGSPY LAAEA+ F KI++LN+L L VS HAN +M Sbjct 74 VKALVDGIAADHGRLDVVVNNAGGSPYVLAAEASAKFSMKILQLNLLGALSVSTHANAVM 133 Query 129 QAQPNGGSIVNICSVSGRRPTPGTAAYGAAKAGLENLTTTLAVEWAPKVRVNAVVVGMVE 188 Q Q GGSIVNI SVSG RPTPGTAAYGAAKAG++NLT TLAVEWAP+VRVN+VVVGMVE Sbjct 134 QKQDGGGSIVNISSVSGHRPTPGTAAYGAAKAGIDNLTRTLAVEWAPRVRVNSVVVGMVE 193 Query 189 TERSELFYGDAESIARVAATVPLGRLARPADIGWAAAFLASDAASYISGATLEVHGGGEP 248 TE+SELFYGDA+SIA ++ VPLGRLARP DIGWA AFLASDAASYISGA+LEVHGGGEP Sbjct 194 TEQSELFYGDADSIAAISKNVPLGRLARPEDIGWATAFLASDAASYISGASLEVHGGGEP 253 Query 249 PPYLGASSAN 258 P YL ++A+ Sbjct 254 PHYLSTTTAD 263 >gi|41406615|ref|NP_959451.1| short chain dehydrogenase [Mycobacterium avium subsp. paratuberculosis K-10] gi|41394964|gb|AAS02834.1| hypothetical protein MAP_0517 [Mycobacterium avium subsp. paratuberculosis K-10] gi|336458405|gb|EGO37379.1| dehydrogenase of unknown specificity, short-chain alcohol dehydrogenase like protein [Mycobacterium avium subsp. paratuberculosis S397] Length=265 Score = 380 bits (976), Expect = 1e-103, Method: Compositional matrix adjust. Identities = 196/262 (75%), Positives = 225/262 (86%), Gaps = 4/262 (1%) Query 1 VTLAEA----ADAINFGLAGRVVLVTGGVRGVGAGISSVFAEQGATVITCARRAVDGQPY 56 +T AEA A+AIN GL GRVVLVTGGVRGVGAGISSVFA QGATV+TCARRAV+G PY Sbjct 1 MTRAEACPPFAEAINLGLTGRVVLVTGGVRGVGAGISSVFAAQGATVVTCARRAVEGLPY 60 Query 57 EFHRCDIRDEDSVKRLVGEIGERHGRLDMLVNNAGGSPYALAAEATHNFHRKIVELNVLA 116 EFH CD+RD+D+VK L+ I +RHGRLD++VNNAGGSPY L AE++ F+RKI+ELN++ Sbjct 61 EFHSCDVRDDDAVKALIDTIADRHGRLDVVVNNAGGSPYVLTAESSAKFNRKIIELNLIG 120 Query 117 PLLVSQHANVLMQAQPNGGSIVNICSVSGRRPTPGTAAYGAAKAGLENLTTTLAVEWAPK 176 L VSQHAN MQ Q GGSIVNICS+SGRRP+PGT AYGAAKAGLE+LT TLAVEW PK Sbjct 121 ALSVSQHANAHMQKQAQGGSIVNICSLSGRRPSPGTGAYGAAKAGLESLTQTLAVEWGPK 180 Query 177 VRVNAVVVGMVETERSELFYGDAESIARVAATVPLGRLARPADIGWAAAFLASDAASYIS 236 VRVNA VVGMVETE+SELFYGDA+SIA ++ VPLGRLA+PADIGWAAAFLASDAA YIS Sbjct 181 VRVNACVVGMVETEQSELFYGDADSIAAISKNVPLGRLAKPADIGWAAAFLASDAACYIS 240 Query 237 GATLEVHGGGEPPPYLGASSAN 258 GA+LEVHGGGEPP YL ++A+ Sbjct 241 GASLEVHGGGEPPHYLATTNAS 262 >gi|108801645|ref|YP_641842.1| short chain dehydrogenase [Mycobacterium sp. MCS] gi|119870796|ref|YP_940748.1| short chain dehydrogenase [Mycobacterium sp. KMS] gi|108772064|gb|ABG10786.1| short-chain dehydrogenase/reductase SDR [Mycobacterium sp. MCS] gi|119696885|gb|ABL93958.1| short-chain dehydrogenase/reductase SDR [Mycobacterium sp. KMS] Length=244 Score = 376 bits (966), Expect = 1e-102, Method: Compositional matrix adjust. Identities = 183/241 (76%), Positives = 208/241 (87%), Gaps = 0/241 (0%) Query 18 VVLVTGGVRGVGAGISSVFAEQGATVITCARRAVDGQPYEFHRCDIRDEDSVKRLVGEIG 77 +VLVTGGVRGVGAGIS+VFA QGATV+TCARR VDG PYEFH CDIRD+DSVK L+ I Sbjct 1 MVLVTGGVRGVGAGISAVFAAQGATVVTCARRPVDGSPYEFHPCDIRDDDSVKSLIDAIV 60 Query 78 ERHGRLDMLVNNAGGSPYALAAEATHNFHRKIVELNVLAPLLVSQHANVLMQAQPNGGSI 137 HGRLD+++NNAGGSPY AAEA+ F RKIVELN+L L VS HAN +MQ Q +GGSI Sbjct 61 GAHGRLDVVINNAGGSPYVPAAEASAKFSRKIVELNLLGALSVSTHANAVMQTQESGGSI 120 Query 138 VNICSVSGRRPTPGTAAYGAAKAGLENLTTTLAVEWAPKVRVNAVVVGMVETERSELFYG 197 VNI SVS RRPTPGT AYGAAKAG+EN+TTTLAVEWAPKVRVN+VVVGMVETE++ELFYG Sbjct 121 VNITSVSARRPTPGTVAYGAAKAGVENMTTTLAVEWAPKVRVNSVVVGMVETEQAELFYG 180 Query 198 DAESIARVAATVPLGRLARPADIGWAAAFLASDAASYISGATLEVHGGGEPPPYLGASSA 257 DA+SIA ++ VPLGRLA+P DIGWA AFLASDAASYISGA+LEVHGGGEPP YL ++A Sbjct 181 DADSIAAISRNVPLGRLAKPDDIGWATAFLASDAASYISGASLEVHGGGEPPHYLSTTTA 240 Query 258 N 258 + Sbjct 241 D 241 >gi|126437631|ref|YP_001073322.1| short chain dehydrogenase [Mycobacterium sp. JLS] gi|126237431|gb|ABO00832.1| short-chain dehydrogenase/reductase SDR [Mycobacterium sp. JLS] Length=244 Score = 375 bits (964), Expect = 3e-102, Method: Compositional matrix adjust. Identities = 183/241 (76%), Positives = 207/241 (86%), Gaps = 0/241 (0%) Query 18 VVLVTGGVRGVGAGISSVFAEQGATVITCARRAVDGQPYEFHRCDIRDEDSVKRLVGEIG 77 +VLVTGGVRGVGAGIS+VFA QGATV+TCARR VDG PYEFH CDIRD+DSVK L+ I Sbjct 1 MVLVTGGVRGVGAGISAVFAAQGATVVTCARRPVDGSPYEFHPCDIRDDDSVKSLIDAIV 60 Query 78 ERHGRLDMLVNNAGGSPYALAAEATHNFHRKIVELNVLAPLLVSQHANVLMQAQPNGGSI 137 HGRLD+++NNAGGSPY AAEA+ F RKIVELN+L L VS HAN +MQ Q GGSI Sbjct 61 GAHGRLDVVINNAGGSPYVPAAEASAKFSRKIVELNLLGALSVSTHANAVMQTQERGGSI 120 Query 138 VNICSVSGRRPTPGTAAYGAAKAGLENLTTTLAVEWAPKVRVNAVVVGMVETERSELFYG 197 VNI SVS RRPTPGT AYGAAKAG+EN+TTTLAVEWAPKVRVN+VVVGMVETE++ELFYG Sbjct 121 VNITSVSARRPTPGTVAYGAAKAGVENMTTTLAVEWAPKVRVNSVVVGMVETEQAELFYG 180 Query 198 DAESIARVAATVPLGRLARPADIGWAAAFLASDAASYISGATLEVHGGGEPPPYLGASSA 257 DA+SIA ++ VPLGRLA+P DIGWA AFLASDAASYISGA+LEVHGGGEPP YL ++A Sbjct 181 DADSIAAISRNVPLGRLAKPDDIGWATAFLASDAASYISGASLEVHGGGEPPHYLSTTTA 240 Query 258 N 258 + Sbjct 241 D 241 >gi|254822632|ref|ZP_05227633.1| short chain dehydrogenase [Mycobacterium intracellulare ATCC 13950] Length=252 Score = 373 bits (958), Expect = 1e-101, Method: Compositional matrix adjust. Identities = 187/249 (76%), Positives = 218/249 (88%), Gaps = 0/249 (0%) Query 10 INFGLAGRVVLVTGGVRGVGAGISSVFAEQGATVITCARRAVDGQPYEFHRCDIRDEDSV 69 +N GLAGRVVLVTGGVRGVGAGISSVFA QGATV+TCARR V+G P+EFH CD+RD+D+V Sbjct 1 MNLGLAGRVVLVTGGVRGVGAGISSVFAAQGATVVTCARRPVEGSPHEFHSCDVRDDDAV 60 Query 70 KRLVGEIGERHGRLDMLVNNAGGSPYALAAEATHNFHRKIVELNVLAPLLVSQHANVLMQ 129 + L+ + +RHG LD++VNNAGGSPY L AE++ F+RKI+ELN++ L VSQHAN MQ Sbjct 61 RELIDTVADRHGGLDVVVNNAGGSPYVLTAESSAKFNRKIIELNLIGALSVSQHANDKMQ 120 Query 130 AQPNGGSIVNICSVSGRRPTPGTAAYGAAKAGLENLTTTLAVEWAPKVRVNAVVVGMVET 189 AQP GGSI+NICS+SGRRP+PGT AYGAAKAGLE+LT TLAVEW PKVRVNA VVGMVET Sbjct 121 AQPRGGSIINICSLSGRRPSPGTGAYGAAKAGLESLTQTLAVEWGPKVRVNACVVGMVET 180 Query 190 ERSELFYGDAESIARVAATVPLGRLARPADIGWAAAFLASDAASYISGATLEVHGGGEPP 249 E+SELFYG+AESIA ++ VPLGRLA+P DIGWAAAFLASDAASYISGA+LEVHGGGEPP Sbjct 181 EQSELFYGNAESIAAISKNVPLGRLAKPDDIGWAAAFLASDAASYISGASLEVHGGGEPP 240 Query 250 PYLGASSAN 258 YL ++AN Sbjct 241 HYLATTNAN 249 >gi|118468241|ref|YP_890226.1| short chain dehydrogenase [Mycobacterium smegmatis str. MC2 155] gi|118169528|gb|ABK70424.1| short chain dehydrogenase [Mycobacterium smegmatis str. MC2 155] Length=260 Score = 371 bits (952), Expect = 7e-101, Method: Compositional matrix adjust. Identities = 190/251 (76%), Positives = 218/251 (87%), Gaps = 0/251 (0%) Query 7 ADAINFGLAGRVVLVTGGVRGVGAGISSVFAEQGATVITCARRAVDGQPYEFHRCDIRDE 66 A AIN GL G+VVLVTGGVRGVGAGIS+VFA QGATV+TCARR V+G PYEFH CD+RD+ Sbjct 7 AGAINLGLTGKVVLVTGGVRGVGAGISAVFAGQGATVVTCARRPVEGLPYEFHSCDVRDD 66 Query 67 DSVKRLVGEIGERHGRLDMLVNNAGGSPYALAAEATHNFHRKIVELNVLAPLLVSQHANV 126 +SV L+ I E+HGR+D++VNNAGGSPY A+EA+ F KI+ELN+L PL VSQHAN Sbjct 67 ESVAALITAIVEKHGRIDVVVNNAGGSPYVPASEASARFSSKIIELNLLGPLSVSQHANA 126 Query 127 LMQAQPNGGSIVNICSVSGRRPTPGTAAYGAAKAGLENLTTTLAVEWAPKVRVNAVVVGM 186 +MQ Q GG IVNI SVSGRRPTPGTAAYGAAKAG++NLT TLAVEWAPKVRVN+VVVGM Sbjct 127 VMQNQDTGGVIVNISSVSGRRPTPGTAAYGAAKAGVDNLTETLAVEWAPKVRVNSVVVGM 186 Query 187 VETERSELFYGDAESIARVAATVPLGRLARPADIGWAAAFLASDAASYISGATLEVHGGG 246 VETE+SELFYGDA+SIA ++ VPLGRLA+PADIGWAAAFLASDAASYISGA+LEVHGGG Sbjct 187 VETEQSELFYGDADSIAAISKNVPLGRLAKPADIGWAAAFLASDAASYISGASLEVHGGG 246 Query 247 EPPPYLGASSA 257 EPP YL ++A Sbjct 247 EPPHYLATTTA 257 >gi|296166581|ref|ZP_06849011.1| 3-oxoacyl-[acyl-carrier-protein] reductase [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295898067|gb|EFG77643.1| 3-oxoacyl-[acyl-carrier-protein] reductase [Mycobacterium parascrofulaceum ATCC BAA-614] Length=250 Score = 370 bits (951), Expect = 9e-101, Method: Compositional matrix adjust. Identities = 189/247 (77%), Positives = 217/247 (88%), Gaps = 0/247 (0%) Query 12 FGLAGRVVLVTGGVRGVGAGISSVFAEQGATVITCARRAVDGQPYEFHRCDIRDEDSVKR 71 GLAGRVVLVTGGVRGVGAGISSVFA QGATVITCARRAV+G PYEFH CD+RD+D+VK Sbjct 1 MGLAGRVVLVTGGVRGVGAGISSVFAGQGATVITCARRAVEGLPYEFHSCDVRDDDAVKA 60 Query 72 LVGEIGERHGRLDMLVNNAGGSPYALAAEATHNFHRKIVELNVLAPLLVSQHANVLMQAQ 131 L+ I E+HGRLD++VNNAGGSPY AE++ F+RKI+ELN++ L VSQHAN MQ Q Sbjct 61 LIDSIVEQHGRLDVVVNNAGGSPYVPTAESSAKFNRKIIELNLIGALSVSQHANENMQNQ 120 Query 132 PNGGSIVNICSVSGRRPTPGTAAYGAAKAGLENLTTTLAVEWAPKVRVNAVVVGMVETER 191 P+GGSI+NICS+SGRRP+PGT AYGAAKAGLE+LT TLAVEW PKVRVNA VVGMVETE+ Sbjct 121 PHGGSIINICSLSGRRPSPGTGAYGAAKAGLESLTQTLAVEWGPKVRVNACVVGMVETEQ 180 Query 192 SELFYGDAESIARVAATVPLGRLARPADIGWAAAFLASDAASYISGATLEVHGGGEPPPY 251 SELFYGDA+SIA ++ VPLGRLA+P DIGWAAAFLASDAASYISGA+LEVHGGGEPP Y Sbjct 181 SELFYGDADSIAAISKNVPLGRLAQPDDIGWAAAFLASDAASYISGASLEVHGGGEPPHY 240 Query 252 LGASSAN 258 L ++A+ Sbjct 241 LATTNAS 247 >gi|333992343|ref|YP_004524957.1| short-chain dehydrogenase [Mycobacterium sp. JDM601] gi|333488311|gb|AEF37703.1| short-chain type dehydrogenase/reductase [Mycobacterium sp. JDM601] Length=239 Score = 370 bits (949), Expect = 1e-100, Method: Compositional matrix adjust. Identities = 188/239 (79%), Positives = 217/239 (91%), Gaps = 0/239 (0%) Query 21 VTGGVRGVGAGISSVFAEQGATVITCARRAVDGQPYEFHRCDIRDEDSVKRLVGEIGERH 80 +TGGVRGVGAGIS+VFA+QGATV+TCARR +DG PYEFH CD+RD+D+V+ L+ + +H Sbjct 1 MTGGVRGVGAGISAVFADQGATVVTCARRPMDGLPYEFHACDVRDDDAVRGLIETVVAKH 60 Query 81 GRLDMLVNNAGGSPYALAAEATHNFHRKIVELNVLAPLLVSQHANVLMQAQPNGGSIVNI 140 GRLD++VNNAGGSPYA AA+A+ NF RKI+ELN+LAPL V+QHAN +MQAQ GGSIVN+ Sbjct 61 GRLDVVVNNAGGSPYAPAAQASANFSRKIIELNLLAPLQVAQHANAVMQAQDCGGSIVNV 120 Query 141 CSVSGRRPTPGTAAYGAAKAGLENLTTTLAVEWAPKVRVNAVVVGMVETERSELFYGDAE 200 SVSGRRP+PGTAAY AAKAG+++LT TLAVEWAPKVRVN+VVVGMVETE+SELFYGDAE Sbjct 121 TSVSGRRPSPGTAAYSAAKAGVDSLTATLAVEWAPKVRVNSVVVGMVETEQSELFYGDAE 180 Query 201 SIARVAATVPLGRLARPADIGWAAAFLASDAASYISGATLEVHGGGEPPPYLGASSANK 259 SIA VAATVPLGRLA+PADIGWAAAFLASDAASYISGA+LE HGGGEPP YL ASSANK Sbjct 181 SIAAVAATVPLGRLAKPADIGWAAAFLASDAASYISGASLEAHGGGEPPAYLDASSANK 239 >gi|120406213|ref|YP_956042.1| short chain dehydrogenase [Mycobacterium vanbaalenii PYR-1] gi|119959031|gb|ABM16036.1| short-chain dehydrogenase/reductase SDR [Mycobacterium vanbaalenii PYR-1] Length=265 Score = 366 bits (940), Expect = 2e-99, Method: Compositional matrix adjust. Identities = 188/249 (76%), Positives = 210/249 (85%), Gaps = 0/249 (0%) Query 10 INFGLAGRVVLVTGGVRGVGAGISSVFAEQGATVITCARRAVDGQPYEFHRCDIRDEDSV 69 I GL GRVVLVTGGVRGVGAGIS VFA+QGATV+TCARR V+G PYEF CDIR++DSV Sbjct 12 IALGLTGRVVLVTGGVRGVGAGISKVFADQGATVVTCARRPVEGSPYEFRSCDIREDDSV 71 Query 70 KRLVGEIGERHGRLDMLVNNAGGSPYALAAEATHNFHRKIVELNVLAPLLVSQHANVLMQ 129 K LV I HGRLD++VNNAGGSPY LAA+A+ F KIV LN+L L VS HAN MQ Sbjct 72 KGLVEGIVSDHGRLDVVVNNAGGSPYVLAADASARFSAKIVALNLLGALSVSTHANAAMQ 131 Query 130 AQPNGGSIVNICSVSGRRPTPGTAAYGAAKAGLENLTTTLAVEWAPKVRVNAVVVGMVET 189 AQ GGSIVNI SVSGRRPTPGT AYGAAKAG+EN+T TLAVEWAPKVRVN+VVVGMVET Sbjct 132 AQAAGGSIVNITSVSGRRPTPGTVAYGAAKAGMENMTATLAVEWAPKVRVNSVVVGMVET 191 Query 190 ERSELFYGDAESIARVAATVPLGRLARPADIGWAAAFLASDAASYISGATLEVHGGGEPP 249 E+SELFYGDA+SIA ++ VPLGRLA+P DIGWA AFLASDAASYISGA+LEVHGGGEPP Sbjct 192 EQSELFYGDADSIAAISKNVPLGRLAKPEDIGWATAFLASDAASYISGASLEVHGGGEPP 251 Query 250 PYLGASSAN 258 YL ++A+ Sbjct 252 HYLATTTAD 260 >gi|118465785|ref|YP_879891.1| short chain dehydrogenase [Mycobacterium avium 104] gi|254773568|ref|ZP_05215084.1| short chain dehydrogenase [Mycobacterium avium subsp. avium ATCC 25291] gi|118167072|gb|ABK67969.1| short chain dehydrogenase [Mycobacterium avium 104] Length=244 Score = 364 bits (934), Expect = 8e-99, Method: Compositional matrix adjust. Identities = 183/241 (76%), Positives = 211/241 (88%), Gaps = 0/241 (0%) Query 18 VVLVTGGVRGVGAGISSVFAEQGATVITCARRAVDGQPYEFHRCDIRDEDSVKRLVGEIG 77 +VLVTGGVRGVGAGISSVFA QGATV+TCARRAV+G PYEFH CD+RD+D+VK L+ I Sbjct 1 MVLVTGGVRGVGAGISSVFAAQGATVVTCARRAVEGLPYEFHSCDVRDDDAVKALIDTIA 60 Query 78 ERHGRLDMLVNNAGGSPYALAAEATHNFHRKIVELNVLAPLLVSQHANVLMQAQPNGGSI 137 +RHGRLD++VNNAGGSPY L AE++ F+RKI+ELN++ L VSQHAN MQ Q GGSI Sbjct 61 DRHGRLDVVVNNAGGSPYVLTAESSAKFNRKIIELNLIGALSVSQHANAHMQKQAQGGSI 120 Query 138 VNICSVSGRRPTPGTAAYGAAKAGLENLTTTLAVEWAPKVRVNAVVVGMVETERSELFYG 197 VNICS+SGRRP+PGT AYGAAKAGLE+LT TLAVEW PKVRVNA VVGMVETE+SELFYG Sbjct 121 VNICSLSGRRPSPGTGAYGAAKAGLESLTQTLAVEWGPKVRVNACVVGMVETEQSELFYG 180 Query 198 DAESIARVAATVPLGRLARPADIGWAAAFLASDAASYISGATLEVHGGGEPPPYLGASSA 257 DA+SIA ++ VPLGRLA+PADIGWAAAFLASDAA YISGA+LEVHGGGEPP YL ++A Sbjct 181 DADSIAAISKNVPLGRLAKPADIGWAAAFLASDAACYISGASLEVHGGGEPPHYLATTNA 240 Query 258 N 258 + Sbjct 241 S 241 >gi|145222083|ref|YP_001132761.1| short chain dehydrogenase [Mycobacterium gilvum PYR-GCK] gi|145214569|gb|ABP43973.1| short-chain dehydrogenase/reductase SDR [Mycobacterium gilvum PYR-GCK] Length=233 Score = 352 bits (903), Expect = 3e-95, Method: Compositional matrix adjust. Identities = 171/231 (75%), Positives = 195/231 (85%), Gaps = 0/231 (0%) Query 28 VGAGISSVFAEQGATVITCARRAVDGQPYEFHRCDIRDEDSVKRLVGEIGERHGRLDMLV 87 +GAGIS VFA+QGATVITCARR V+ P+EF CDIRD+D+VK LV I HGRLD++V Sbjct 1 MGAGISRVFADQGATVITCARRPVEDSPFEFRACDIRDDDAVKALVDGIASDHGRLDVVV 60 Query 88 NNAGGSPYALAAEATHNFHRKIVELNVLAPLLVSQHANVLMQAQPNGGSIVNICSVSGRR 147 NNAGGSPY LAAEA+ F KIV LN+L L VS HAN +MQ Q GGSIVNI SVSG R Sbjct 61 NNAGGSPYVLAAEASAKFSTKIVALNLLGALSVSTHANSVMQKQDTGGSIVNISSVSGHR 120 Query 148 PTPGTAAYGAAKAGLENLTTTLAVEWAPKVRVNAVVVGMVETERSELFYGDAESIARVAA 207 PTPGTAAYGAAKAG++NLT+TLAVEWAPKVRVN+VVVGMVETE+SELFYGDA+SIA ++ Sbjct 121 PTPGTAAYGAAKAGIDNLTSTLAVEWAPKVRVNSVVVGMVETEQSELFYGDADSIAAISK 180 Query 208 TVPLGRLARPADIGWAAAFLASDAASYISGATLEVHGGGEPPPYLGASSAN 258 VPLGRLA+P DIGWA AFLASDAASYISGA+LEVHGGGEPP YL ++A+ Sbjct 181 NVPLGRLAQPEDIGWATAFLASDAASYISGASLEVHGGGEPPHYLSTTTAD 231 >gi|169627710|ref|YP_001701359.1| short chain dehydrogenase [Mycobacterium abscessus ATCC 19977] gi|169239677|emb|CAM60705.1| Probable short-chain dehydrogenase/reductase [Mycobacterium abscessus] Length=260 Score = 349 bits (895), Expect = 2e-94, Method: Compositional matrix adjust. Identities = 172/249 (70%), Positives = 203/249 (82%), Gaps = 1/249 (0%) Query 11 NFGLAGRVVLVTGGVRGVGAGISSVFAEQGATVITCARRAVDGQPYEFHRCDIRDEDSVK 70 + GL GRVVLVTGGVRGVGAGIS VFA+QGATV+TCARR D PYEFH CD+RDE+SV Sbjct 6 DLGLEGRVVLVTGGVRGVGAGISQVFADQGATVVTCARRPGDA-PYEFHSCDVRDEESVD 64 Query 71 RLVGEIGERHGRLDMLVNNAGGSPYALAAEATHNFHRKIVELNVLAPLLVSQHANVLMQA 130 L+G I HGRLD +VNNAGG+P+ALAA+A+HNFHRKI+ELN+L+ LLVSQ AN +MQ Sbjct 65 TLIGAIVAAHGRLDAVVNNAGGAPFALAADASHNFHRKIIELNLLSALLVSQRANAVMQK 124 Query 131 QPNGGSIVNICSVSGRRPTPGTAAYGAAKAGLENLTTTLAVEWAPKVRVNAVVVGMVETE 190 Q GG+IVNI SVS RP+PGTAAYGAAKAGLE+LT +LAVEWAPKVRVNA+ GM+ TE Sbjct 125 QDGGGTIVNITSVSAGRPSPGTAAYGAAKAGLESLTRSLAVEWAPKVRVNALAAGMIRTE 184 Query 191 RSELFYGDAESIARVAATVPLGRLARPADIGWAAAFLASDAASYISGATLEVHGGGEPPP 250 SE+ YGD + IA V ATVPLGRLA P +IGW AAFLAS +SY++G+ L VHGGGE P Sbjct 185 LSEMHYGDEDGIAAVGATVPLGRLANPDEIGWTAAFLASPLSSYVTGSVLTVHGGGERPA 244 Query 251 YLGASSANK 259 +L A++ N Sbjct 245 FLDAANVNS 253 >gi|226364161|ref|YP_002781943.1| short chain dehydrogenase [Rhodococcus opacus B4] gi|226242650|dbj|BAH52998.1| putative oxidoreductase [Rhodococcus opacus B4] Length=268 Score = 323 bits (828), Expect = 2e-86, Method: Compositional matrix adjust. Identities = 169/247 (69%), Positives = 194/247 (79%), Gaps = 6/247 (2%) Query 12 FGLAGRVVLVTGGVRGVGAGISSVFAEQGATVITCARRA------VDGQPYEFHRCDIRD 65 F L G VVLVTGGVRGVGAGIS F GATV+ CARR VDG+ EF CDIRD Sbjct 5 FNLDGAVVLVTGGVRGVGAGISRTFLRAGATVVACARRPGDEPVEVDGRAAEFLPCDIRD 64 Query 66 EDSVKRLVGEIGERHGRLDMLVNNAGGSPYALAAEATHNFHRKIVELNVLAPLLVSQHAN 125 + V+ LV I ERHGRLD+LVNNAGG+P+ALAAEA+ FH KIVELN+LAPLLVSQ AN Sbjct 65 PEQVQGLVDRIVERHGRLDVLVNNAGGAPFALAAEASPKFHSKIVELNLLAPLLVSQAAN 124 Query 126 VLMQAQPNGGSIVNICSVSGRRPTPGTAAYGAAKAGLENLTTTLAVEWAPKVRVNAVVVG 185 +MQAQ +GG+IVNI SVSG RP+PGTAAYGAAKAG+++LTT+LAVEWAPKVRVNAVVVG Sbjct 125 AVMQAQASGGAIVNISSVSGSRPSPGTAAYGAAKAGVDSLTTSLAVEWAPKVRVNAVVVG 184 Query 186 MVETERSELFYGDAESIARVAATVPLGRLARPADIGWAAAFLASDAASYISGATLEVHGG 245 +V+TE + L YGD IA V TVPLGR+A P D+G A FLAS ASY+SG+TL VHGG Sbjct 185 LVQTELAHLHYGDDAGIAAVGETVPLGRMAVPEDVGNCAVFLASPLASYVSGSTLTVHGG 244 Query 246 GEPPPYL 252 GE P +L Sbjct 245 GERPAFL 251 >gi|319947734|ref|ZP_08021940.1| short chain dehydrogenase [Dietzia cinnamea P4] gi|319438584|gb|EFV93498.1| short chain dehydrogenase [Dietzia cinnamea P4] Length=257 Score = 323 bits (828), Expect = 2e-86, Method: Compositional matrix adjust. Identities = 163/254 (65%), Positives = 203/254 (80%), Gaps = 6/254 (2%) Query 10 INFGLAGRVVLVTGGVRGVGAGISSVFAEQGATVITCARRAVDG----QPYEFHRCDIRD 65 I+ GLAG+VVLVTGGVRGVGAGIS+VF E GA V+TCARR D EFH D+RD Sbjct 4 IDLGLAGKVVLVTGGVRGVGAGISAVFREAGAVVVTCARRPADEGSDVADLEFHSVDLRD 63 Query 66 EDSVKRLVGEIGERHGRLDMLVNNAGGSPYALAAEATHNFHRKIVELNVLAPLLVSQHAN 125 D+V+ ++ +I RHGRLD++VNNAGG+P+ALAAEA+ NFH KIV LN+L+ L VSQ AN Sbjct 64 ADAVRAMIDDIVARHGRLDVVVNNAGGAPFALAAEASANFHAKIVALNLLSALTVSQEAN 123 Query 126 VLMQAQPNGGSIVNICSVSGRRPTPGTAAYGAAKAGLENLTTTLAVEWAPKVRVNAVVVG 185 +MQ P GG+I+NI SVSG RP+PGTA+YGAAKAG+++LT +LAVEWAP VRVN+VVVG Sbjct 124 RVMQ--PTGGAIINISSVSGHRPSPGTASYGAAKAGIDSLTQSLAVEWAPAVRVNSVVVG 181 Query 186 MVETERSELFYGDAESIARVAATVPLGRLARPADIGWAAAFLASDAASYISGATLEVHGG 245 V+TE++EL YGDA+ +A V AT+P+GR+A PAD+G AAAFLAS A+YI+GA L VHGG Sbjct 182 PVKTEQAELHYGDADGVAAVDATIPMGRMAEPADVGRAAAFLASPLAAYITGAELLVHGG 241 Query 246 GEPPPYLGASSANK 259 GE P +L AS+A Sbjct 242 GEKPAFLSASTAEN 255 >gi|333918630|ref|YP_004492211.1| putative oxidoreductase [Amycolicicoccus subflavus DQS3-9A1] gi|333480851|gb|AEF39411.1| Putative oxidoreductase [Amycolicicoccus subflavus DQS3-9A1] Length=266 Score = 320 bits (821), Expect = 9e-86, Method: Compositional matrix adjust. Identities = 169/257 (66%), Positives = 195/257 (76%), Gaps = 6/257 (2%) Query 9 AINFGLAGRVVLVTGGVRGVGAGISSVFAEQGATVITCARRA------VDGQPYEFHRCD 62 A +FGL G VVLVTGGVRGVGAGI+ F GATV+ CAR G+ EF CD Sbjct 3 APSFGLDGAVVLVTGGVRGVGAGITRTFLRLGATVVCCARNEPGDPVHAAGRNAEFLPCD 62 Query 63 IRDEDSVKRLVGEIGERHGRLDMLVNNAGGSPYALAAEATHNFHRKIVELNVLAPLLVSQ 122 +RD+ SV LV I +RHG++D+ VNNAGG+PYALAA+A+ FH KIV LN+LAPL V+Q Sbjct 63 VRDDQSVADLVDSIIDRHGKIDVAVNNAGGAPYALAADASPRFHEKIVSLNLLAPLSVAQ 122 Query 123 HANVLMQAQPNGGSIVNICSVSGRRPTPGTAAYGAAKAGLENLTTTLAVEWAPKVRVNAV 182 HAN MQAQ GGSIVNICSVSG RP+PGTAAYGAAKAGL+NLT +LAVEWAPKVRVNA+ Sbjct 123 HANRYMQAQEQGGSIVNICSVSGTRPSPGTAAYGAAKAGLDNLTRSLAVEWAPKVRVNAL 182 Query 183 VVGMVETERSELFYGDAESIARVAATVPLGRLARPADIGWAAAFLASDAASYISGATLEV 242 VGMV TE S L YGD + IA V ATVPLGRLA P +IG AAFLAS ASY++GA LEV Sbjct 183 RVGMVHTELSALHYGDDDGIAAVGATVPLGRLAAPEEIGMCAAFLASPLASYVTGAALEV 242 Query 243 HGGGEPPPYLGASSANK 259 HGGGE P +L A++A Sbjct 243 HGGGERPAFLAAATAKN 259 >gi|111021625|ref|YP_704597.1| short chain dehydrogenase [Rhodococcus jostii RHA1] gi|110821155|gb|ABG96439.1| short chain dehydrogenase [Rhodococcus jostii RHA1] Length=260 Score = 318 bits (816), Expect = 4e-85, Method: Compositional matrix adjust. Identities = 166/255 (66%), Positives = 198/255 (78%), Gaps = 6/255 (2%) Query 10 INFGLAGRVVLVTGGVRGVGAGISSVFAEQGATVITCARRA------VDGQPYEFHRCDI 63 ++ GL G +VLVTGGVRGVGAGIS F GATV+ CARR VDG+ EF CDI Sbjct 1 MDSGLNGAIVLVTGGVRGVGAGISRTFLRAGATVVACARRPGEAPVEVDGRAIEFLPCDI 60 Query 64 RDEDSVKRLVGEIGERHGRLDMLVNNAGGSPYALAAEATHNFHRKIVELNVLAPLLVSQH 123 RD + V+ LV I ERHGRLD+LVNNAGG+P+ALAA+A+ FH KIVELN+LAPLLVSQ Sbjct 61 RDPEQVQGLVDRIVERHGRLDVLVNNAGGAPFALAADASPKFHSKIVELNLLAPLLVSQT 120 Query 124 ANVLMQAQPNGGSIVNICSVSGRRPTPGTAAYGAAKAGLENLTTTLAVEWAPKVRVNAVV 183 AN +MQ Q +GG+IVNI SVSG RP+PGTAAYGAAKAG+++LT +LAVEWAPKVRVN+VV Sbjct 121 ANAVMQKQDSGGAIVNISSVSGSRPSPGTAAYGAAKAGVDSLTGSLAVEWAPKVRVNSVV 180 Query 184 VGMVETERSELFYGDAESIARVAATVPLGRLARPADIGWAAAFLASDAASYISGATLEVH 243 VG+V TE + L YGD IA V TVPLGR+A P DIG A FLAS A+Y+SG+TL VH Sbjct 181 VGLVRTELAHLHYGDEAGIAAVGDTVPLGRMACPEDIGNCAVFLASPLAAYVSGSTLTVH 240 Query 244 GGGEPPPYLGASSAN 258 GGGE P +L A++A+ Sbjct 241 GGGERPAFLAAATAS 255 >gi|325674910|ref|ZP_08154597.1| trans-2-enoyl-CoA reductase (NADPH) [Rhodococcus equi ATCC 33707] gi|325554496|gb|EGD24171.1| trans-2-enoyl-CoA reductase (NADPH) [Rhodococcus equi ATCC 33707] Length=254 Score = 311 bits (797), Expect = 6e-83, Method: Compositional matrix adjust. Identities = 155/253 (62%), Positives = 195/253 (78%), Gaps = 6/253 (2%) Query 10 INFGLAGRVVLVTGGVRGVGAGISSVFAEQGATVITCARR------AVDGQPYEFHRCDI 63 ++ GL G+VVLVTGGVRG+GAGIS F GATV+TCARR VDG+ +F CD+ Sbjct 1 MDLGLEGKVVLVTGGVRGIGAGISRSFLRAGATVVTCARRPADEAIEVDGRGVDFIACDV 60 Query 64 RDEDSVKRLVGEIGERHGRLDMLVNNAGGSPYALAAEATHNFHRKIVELNVLAPLLVSQH 123 RD + V+ ++ I ++GRLD +VNNAGG+P+A+AA+A FH KIVELN+LAPLL+SQ Sbjct 61 RDAEQVQSMIDRIVAKYGRLDTVVNNAGGAPFAMAADAGPKFHSKIVELNLLAPLLISQI 120 Query 124 ANVLMQAQPNGGSIVNICSVSGRRPTPGTAAYGAAKAGLENLTTTLAVEWAPKVRVNAVV 183 AN +MQ Q +GGSIV I SVSG RP+PGTAAYGAAKAG+++L +L+VEWAPKVRVN++V Sbjct 121 ANAVMQKQEDGGSIVMISSVSGSRPSPGTAAYGAAKAGIDSLAASLSVEWAPKVRVNSIV 180 Query 184 VGMVETERSELFYGDAESIARVAATVPLGRLARPADIGWAAAFLASDAASYISGATLEVH 243 VG+V+TE S L YGD I V ATVPLGR+ARP DIG A FLAS A+Y+SG+TL VH Sbjct 181 VGLVQTELSHLHYGDEAGIDAVGATVPLGRMARPEDIGNCATFLASPLAAYVSGSTLTVH 240 Query 244 GGGEPPPYLGASS 256 GGGE P +L A++ Sbjct 241 GGGERPAFLAAAT 253 >gi|312138185|ref|YP_004005521.1| short chain dehydrogenase [Rhodococcus equi 103S] gi|311887524|emb|CBH46836.1| short chain dehydrogenase [Rhodococcus equi 103S] Length=254 Score = 309 bits (791), Expect = 3e-82, Method: Compositional matrix adjust. Identities = 154/253 (61%), Positives = 194/253 (77%), Gaps = 6/253 (2%) Query 10 INFGLAGRVVLVTGGVRGVGAGISSVFAEQGATVITCARR------AVDGQPYEFHRCDI 63 ++ GL G+VVLVTGGVRG+GAGIS F GATV+ CARR VDG+ +F CD+ Sbjct 1 MDLGLEGKVVLVTGGVRGIGAGISRSFLRAGATVVACARRPADEAIEVDGRGVDFIACDV 60 Query 64 RDEDSVKRLVGEIGERHGRLDMLVNNAGGSPYALAAEATHNFHRKIVELNVLAPLLVSQH 123 RD + V+ ++ I ++GRLD +VNNAGG+P+A+AA+A FH KIVELN+LAPLL+SQ Sbjct 61 RDAEQVQSMIDRIVAKYGRLDTVVNNAGGAPFAMAADAGPKFHSKIVELNLLAPLLISQI 120 Query 124 ANVLMQAQPNGGSIVNICSVSGRRPTPGTAAYGAAKAGLENLTTTLAVEWAPKVRVNAVV 183 AN +MQ Q +GGSIV I SVSG RP+PGTAAYGAAKAG+++L +L+VEWAPKVRVN++V Sbjct 121 ANAVMQKQEDGGSIVMISSVSGSRPSPGTAAYGAAKAGIDSLAASLSVEWAPKVRVNSIV 180 Query 184 VGMVETERSELFYGDAESIARVAATVPLGRLARPADIGWAAAFLASDAASYISGATLEVH 243 VG+V+TE S L YGD I V ATVPLGR+ARP DIG A FLAS A+Y+SG+TL VH Sbjct 181 VGLVQTELSHLHYGDEAGIDAVGATVPLGRMARPEDIGNCATFLASPLAAYVSGSTLTVH 240 Query 244 GGGEPPPYLGASS 256 GGGE P +L A++ Sbjct 241 GGGERPAFLAAAT 253 >gi|54022478|ref|YP_116720.1| short chain dehydrogenase [Nocardia farcinica IFM 10152] gi|54013986|dbj|BAD55356.1| putative short chain dehydrogenase [Nocardia farcinica IFM 10152] Length=264 Score = 306 bits (783), Expect = 3e-81, Method: Compositional matrix adjust. Identities = 156/254 (62%), Positives = 195/254 (77%), Gaps = 6/254 (2%) Query 10 INFGLAGRVVLVTGGVRGVGAGISSVFAEQGATVITCARR------AVDGQPYEFHRCDI 63 + L+ RVVLVTGGVRGVGAGIS F GATV+ CARR +G+ F CD+ Sbjct 3 LEIDLSDRVVLVTGGVRGVGAGISRAFLAAGATVVACARRPGEQPVTYEGRQAHFLPCDV 62 Query 64 RDEDSVKRLVGEIGERHGRLDMLVNNAGGSPYALAAEATHNFHRKIVELNVLAPLLVSQH 123 RD +V+ L+ + + HGRLD +VNNAGG+P+A AA A+ NFH KI+ELN+++ L VSQ Sbjct 63 RDAAAVRALIETLVDTHGRLDHVVNNAGGAPFASAATASVNFHTKIIELNLMSALWVSQA 122 Query 124 ANVLMQAQPNGGSIVNICSVSGRRPTPGTAAYGAAKAGLENLTTTLAVEWAPKVRVNAVV 183 ANV+MQ QP GGSI+ I S+SG RP+PGTAAYGAAKAG+++LT +L++EWAPKVRVN+++ Sbjct 123 ANVVMQDQPEGGSILMISSLSGHRPSPGTAAYGAAKAGVDSLTQSLSMEWAPKVRVNSLI 182 Query 184 VGMVETERSELFYGDAESIARVAATVPLGRLARPADIGWAAAFLASDAASYISGATLEVH 243 VG VETE SEL YGD + I V AT+PLGRLARP D+G AAAFLAS A+YISGA L+VH Sbjct 183 VGPVETELSELHYGDRDGIEAVGATIPLGRLARPEDVGRAAAFLASPLAAYISGAMLQVH 242 Query 244 GGGEPPPYLGASSA 257 GGGE PP+L AS+A Sbjct 243 GGGERPPFLAASTA 256 >gi|326383134|ref|ZP_08204823.1| short chain dehydrogenase [Gordonia neofelifaecis NRRL B-59395] gi|326198270|gb|EGD55455.1| short chain dehydrogenase [Gordonia neofelifaecis NRRL B-59395] Length=257 Score = 303 bits (777), Expect = 1e-80, Method: Compositional matrix adjust. Identities = 148/248 (60%), Positives = 192/248 (78%), Gaps = 1/248 (0%) Query 10 INFGLAGRVVLVTGGVRGVGAGISSVFAEQGATVITCARRAVDGQPYEFHRCDIRDEDSV 69 +N GL GR +L+TGGVRGVGAGI+ V + GAT + CARR D EF+ CD+RD D+V Sbjct 9 VNLGLTGRTILITGGVRGVGAGIAQVLEDLGATPVVCARRPGD-DGREFYPCDVRDSDAV 67 Query 70 KRLVGEIGERHGRLDMLVNNAGGSPYALAAEATHNFHRKIVELNVLAPLLVSQHANVLMQ 129 ++ I +HGRLD +VNNAGGSP+ALAAEA+ NF RKI+ELN++APL+V++ A+ +M Sbjct 68 AEMIAAIVAKHGRLDGVVNNAGGSPFALAAEASDNFARKIIELNLVAPLIVARAAHKVMT 127 Query 130 AQPNGGSIVNICSVSGRRPTPGTAAYGAAKAGLENLTTTLAVEWAPKVRVNAVVVGMVET 189 Q GG+IVNI SVSG RP+PGT+AYGAAKAGL+N T +LAVEWAP VR+N+V+ G +ET Sbjct 128 EQDGGGAIVNISSVSGHRPSPGTSAYGAAKAGLDNFTASLAVEWAPDVRMNSVICGPIET 187 Query 190 ERSELFYGDAESIARVAATVPLGRLARPADIGWAAAFLASDAASYISGATLEVHGGGEPP 249 E S L YGD + +A V AT+P+GRLA+PADIG A AFL S + +I+G+TL VHGGGE P Sbjct 188 ELSHLHYGDDDGVAAVGATIPMGRLAQPADIGNAVAFLLSPLSQFITGSTLTVHGGGEKP 247 Query 250 PYLGASSA 257 +L A++A Sbjct 248 AFLAAANA 255 >gi|296141496|ref|YP_003648739.1| short-chain dehydrogenase/reductase SDR [Tsukamurella paurometabola DSM 20162] gi|296029630|gb|ADG80400.1| short-chain dehydrogenase/reductase SDR [Tsukamurella paurometabola DSM 20162] Length=261 Score = 295 bits (755), Expect = 4e-78, Method: Compositional matrix adjust. Identities = 155/255 (61%), Positives = 191/255 (75%), Gaps = 7/255 (2%) Query 11 NFGLAGRVVLVTGGVRGVGAGISSVFAEQGATVITCARRA------VDGQPYEFHRCDIR 64 GL G VVLVTGGVRG+GAGI+ VF GATV+ CAR + ++G+ F CD+R Sbjct 7 TLGLDGLVVLVTGGVRGIGAGIARVFLRAGATVVVCARHSPESAISIEGRSAGFVACDVR 66 Query 65 DEDSVKRLVGEIGERHGRLDMLVNNAGGSPYALAAEATHNFHRKIVELNVLAPLLVSQHA 124 + + V L+G I ERHGRLD+LVNNAGG+PY+ AA A+ FH K++ LN+LAPLLV+Q A Sbjct 67 EPEQVDALIGGIVERHGRLDVLVNNAGGAPYSDAATASPRFHDKVIGLNLLAPLLVAQRA 126 Query 125 NVLMQAQPNGGSIVNICSVSGRRPTPGTAAYGAAKAGLENLTTTLAVEWAPKVRVNAVVV 184 N +MQ Q GSI+N+ SVS RP+PGTAAYGAAKAGL++LT +LAVEWAP VRVNA+ V Sbjct 127 NAVMQ-QAGRGSIINVSSVSATRPSPGTAAYGAAKAGLDSLTASLAVEWAPAVRVNALDV 185 Query 185 GMVETERSELFYGDAESIARVAATVPLGRLARPADIGWAAAFLASDAASYISGATLEVHG 244 GMV TE +E YGD IA + ATVPLGRLA P +IG AAFLAS ASY+SGATL VHG Sbjct 186 GMVRTEAAEQHYGDEAGIAAIGATVPLGRLADPEEIGSCAAFLASPLASYVSGATLLVHG 245 Query 245 GGEPPPYLGASSANK 259 GGE P +L A++A++ Sbjct 246 GGERPAFLAAATADR 260 >gi|343928255|ref|ZP_08767709.1| putative oxidoreductase [Gordonia alkanivorans NBRC 16433] gi|343761849|dbj|GAA14635.1| putative oxidoreductase [Gordonia alkanivorans NBRC 16433] Length=262 Score = 293 bits (749), Expect = 2e-77, Method: Compositional matrix adjust. Identities = 151/250 (61%), Positives = 188/250 (76%), Gaps = 4/250 (1%) Query 12 FGLAGRVVLVTGGVRGVGAGISSVFAEQGATVITCARRAV----DGQPYEFHRCDIRDED 67 GL G+VVLVTGG RGVGAGI+ V + GA + C R A D + ++F CD+RD Sbjct 9 LGLVGKVVLVTGGARGVGAGITRVLSCLGARPVICGRNADSLADDLREFDFFSCDVRDAA 68 Query 68 SVKRLVGEIGERHGRLDMLVNNAGGSPYALAAEATHNFHRKIVELNVLAPLLVSQHANVL 127 +V+ +V I R GRLD +VNNAGGSP+ALAA+A+ F KIV+LN+LAPL V++ AN + Sbjct 69 AVEAMVDGIVGRAGRLDGVVNNAGGSPFALAADASVRFASKIVDLNLLAPLAVAKAANAV 128 Query 128 MQAQPNGGSIVNICSVSGRRPTPGTAAYGAAKAGLENLTTTLAVEWAPKVRVNAVVVGMV 187 MQ QP+GG+IVN+ SVSG RP+PGT+AYGAAKAGL+NL T+LAVEWAPKVRVN+VV G V Sbjct 129 MQTQPDGGAIVNVSSVSGHRPSPGTSAYGAAKAGLDNLMTSLAVEWAPKVRVNSVVAGPV 188 Query 188 ETERSELFYGDAESIARVAATVPLGRLARPADIGWAAAFLASDAASYISGATLEVHGGGE 247 ETE+S L YGD +A V AT+PLGR+A P D+G A AFL S A YISG+TL VHGGGE Sbjct 189 ETEQSHLHYGDDAGVAAVGATIPLGRMATPVDVGNAVAFLLSPLAGYISGSTLTVHGGGE 248 Query 248 PPPYLGASSA 257 P +L A++A Sbjct 249 KPAFLDAATA 258 >gi|262203839|ref|YP_003275047.1| short-chain dehydrogenase/reductase SDR [Gordonia bronchialis DSM 43247] gi|262087186|gb|ACY23154.1| short-chain dehydrogenase/reductase SDR [Gordonia bronchialis DSM 43247] Length=267 Score = 281 bits (719), Expect = 7e-74, Method: Compositional matrix adjust. Identities = 144/252 (58%), Positives = 183/252 (73%), Gaps = 4/252 (1%) Query 12 FGLAGRVVLVTGGVRGVGAGISSVFAEQGATVITCARR----AVDGQPYEFHRCDIRDED 67 GL RVVLVTGG RGVGAGI+ GA + C R D + EF CD+RD+ Sbjct 9 LGLTKRVVLVTGGARGVGAGITRTLIALGARPVICGRTPDNVVDDLRAVEFISCDVRDDA 68 Query 68 SVKRLVGEIGERHGRLDMLVNNAGGSPYALAAEATHNFHRKIVELNVLAPLLVSQHANVL 127 +V+ ++ EI ERHGRLD +VNNAGGSP+ LAA+A+ F KIVELN+LAP+ V++HAN Sbjct 69 AVEAMIAEIVERHGRLDGVVNNAGGSPFVLAADASARFTGKIVELNLLAPMSVARHANAA 128 Query 128 MQAQPNGGSIVNICSVSGRRPTPGTAAYGAAKAGLENLTTTLAVEWAPKVRVNAVVVGMV 187 MQ Q +GG+IVN+ SVSG RP+PGT+AYGAAKAGL+N ++LAVEWAP+VRVN+VV G V Sbjct 129 MQQQDSGGAIVNVSSVSGHRPSPGTSAYGAAKAGLDNAMSSLAVEWAPRVRVNSVVAGPV 188 Query 188 ETERSELFYGDAESIARVAATVPLGRLARPADIGWAAAFLASDAASYISGATLEVHGGGE 247 TE+S L YGD +A V AT+P+GR+A AD+G A +FL S A YI+G+TL VHGGGE Sbjct 189 VTEQSHLHYGDDAGVAAVGATIPMGRMATGADVGNAVSFLLSPLAGYITGSTLTVHGGGE 248 Query 248 PPPYLGASSANK 259 P +L A++ N Sbjct 249 RPAFLDAATVNN 260 >gi|119716967|ref|YP_923932.1| short chain dehydrogenase [Nocardioides sp. JS614] gi|119537628|gb|ABL82245.1| short-chain dehydrogenase/reductase SDR [Nocardioides sp. JS614] Length=252 Score = 280 bits (716), Expect = 1e-73, Method: Compositional matrix adjust. Identities = 141/242 (59%), Positives = 176/242 (73%), Gaps = 1/242 (0%) Query 12 FGLAGRVVLVTGGVRGVGAGISSVFAEQGATVITCARRAVDGQPYEFHR-CDIRDEDSVK 70 L GRV LVTGG RG+G GI+ GA+V+TC+R V+ P HR CD+RD D+V+ Sbjct 1 MDLTGRVALVTGGTRGIGLGITRSLLAAGASVVTCSRSDVEPVPGTTHRACDVRDADAVQ 60 Query 71 RLVGEIGERHGRLDMLVNNAGGSPYALAAEATHNFHRKIVELNVLAPLLVSQHANVLMQA 130 LV + E HGRLD+LVNNAGG+P + AA A+ FH KIV LN+LAPL+ +Q AN +MQ Sbjct 61 ALVASVAESHGRLDVLVNNAGGAPASDAATASPRFHEKIVGLNLLAPLVCAQAANAVMQQ 120 Query 131 QPNGGSIVNICSVSGRRPTPGTAAYGAAKAGLENLTTTLAVEWAPKVRVNAVVVGMVETE 190 Q GG IVNI SVS RP P AAYGAAKAGL++LT +LA+EWAPKVRVNA+ VG+ TE Sbjct 121 QDAGGVIVNISSVSANRPAPTIAAYGAAKAGLDSLTASLAMEWAPKVRVNAIDVGLCRTE 180 Query 191 RSELFYGDAESIARVAATVPLGRLARPADIGWAAAFLASDAASYISGATLEVHGGGEPPP 250 ++ YGD S+A + T+PLGR+A P ++G AAFLASD ASY+SGA+L HGGGEPP Sbjct 181 QTGDHYGDDVSVAAIEQTIPLGRMADPIEVGNVAAFLASDLASYVSGASLACHGGGEPPA 240 Query 251 YL 252 +L Sbjct 241 FL 242 >gi|300785272|ref|YP_003765563.1| short-chain dehydrogenase [Amycolatopsis mediterranei U32] gi|299794786|gb|ADJ45161.1| short-chain dehydrogenase [Amycolatopsis mediterranei U32] gi|340526715|gb|AEK41920.1| short chain dehydrogenase [Amycolatopsis mediterranei S699] Length=255 Score = 280 bits (715), Expect = 2e-73, Method: Compositional matrix adjust. Identities = 160/248 (65%), Positives = 187/248 (76%), Gaps = 1/248 (0%) Query 11 NFGLAGRVVLVTGGVRGVGAGISSVFAEQGATVITCARRAVDGQPYEFHRCDIRDEDSVK 70 GLAG VVLVTGGVRGVG GI+ VF GA V+ CARR + EF CD+RDE V Sbjct 4 ELGLAGTVVLVTGGVRGVGRGIADVFLAHGARVVVCARREAPTEA-EFAACDVRDETQVA 62 Query 71 RLVGEIGERHGRLDMLVNNAGGSPYALAAEATHNFHRKIVELNVLAPLLVSQHANVLMQA 130 LV I ERHGRLD +VNNAGG+P+ AAEA+ H KIV+LN+LAPLLV+QHAN +MQ Sbjct 63 ALVEGIVERHGRLDAVVNNAGGAPFVSAAEASPRLHEKIVQLNLLAPLLVAQHANAVMQR 122 Query 131 QPNGGSIVNICSVSGRRPTPGTAAYGAAKAGLENLTTTLAVEWAPKVRVNAVVVGMVETE 190 Q +GG+IV I SVSG RP+PGTAAYGAAKAGL+NLT +LAVEWAPKVRVNA+ VGMV TE Sbjct 123 QDSGGAIVMISSVSGTRPSPGTAAYGAAKAGLDNLTASLAVEWAPKVRVNALDVGMVRTE 182 Query 191 RSELFYGDAESIARVAATVPLGRLARPADIGWAAAFLASDAASYISGATLEVHGGGEPPP 250 ++ L YG ++ V TVPLGRLA PA++G AAFLAS ASY+SGATL VHGGGE P Sbjct 183 QAHLHYGSEAAVEAVGKTVPLGRLAEPAEVGHCAAFLASGLASYVSGATLRVHGGGEVPA 242 Query 251 YLGASSAN 258 +L A+ N Sbjct 243 FLAAADVN 250 >gi|337769602|emb|CCB78315.1| Short chain dehydrogenase [Streptomyces cattleya NRRL 8057] Length=264 Score = 279 bits (713), Expect = 4e-73, Method: Compositional matrix adjust. Identities = 149/252 (60%), Positives = 182/252 (73%), Gaps = 6/252 (2%) Query 14 LAGRVVLVTGGVRGVGAGISSVFAEQGATVITCARR------AVDGQPYEFHRCDIRDED 67 LAGRVV+VTGG RGVGAGI+ F GA V+T AR V G+ H+ D+RD Sbjct 7 LAGRVVVVTGGTRGVGAGIAQAFLAAGAEVVTLARHPPGHPLTVAGRTARHHQADLRDTA 66 Query 68 SVKRLVGEIGERHGRLDMLVNNAGGSPYALAAEATHNFHRKIVELNVLAPLLVSQHANVL 127 +V+R + EI HGRLD LVNNAGG+PY L A+A H ++VELN+LAPL S A + Sbjct 67 AVRRRIEEIATAHGRLDCLVNNAGGTPYRLLADAGPERHARVVELNLLAPLTASLAAYEV 126 Query 128 MQAQPNGGSIVNICSVSGRRPTPGTAAYGAAKAGLENLTTTLAVEWAPKVRVNAVVVGMV 187 M+ Q +GG ++ + SVSG RP+PGTAAYGAAKAGLENL ++AVEWAP +RVN VV GMV Sbjct 127 MRHQASGGCVLMVGSVSGTRPSPGTAAYGAAKAGLENLARSMAVEWAPLIRVNTVVPGMV 186 Query 188 ETERSELFYGDAESIARVAATVPLGRLARPADIGWAAAFLASDAASYISGATLEVHGGGE 247 TER+E YGDA+ +A VA TVPLGRLA PAD+G A FLASD A+YISGA L VHGGGE Sbjct 187 RTERAERHYGDADGVAAVARTVPLGRLAEPADVGDACVFLASDHAAYISGAALLVHGGGE 246 Query 248 PPPYLGASSANK 259 P +L A++AN+ Sbjct 247 RPAFLAAATANQ 258 >gi|345011667|ref|YP_004814021.1| short-chain dehydrogenase/reductase SDR [Streptomyces violaceusniger Tu 4113] gi|344038016|gb|AEM83741.1| short-chain dehydrogenase/reductase SDR [Streptomyces violaceusniger Tu 4113] Length=271 Score = 270 bits (691), Expect = 1e-70, Method: Compositional matrix adjust. Identities = 146/257 (57%), Positives = 173/257 (68%), Gaps = 6/257 (2%) Query 9 AINFGLAGRVVLVTGGVRGVGAGISSVFAEQGATVITCARRA------VDGQPYEFHRCD 62 A++ LAGRV +VTGG RGVGAGI+ GA V+ CAR A DG+ F D Sbjct 2 AVSIDLAGRVAVVTGGTRGVGAGITRALLTAGAEVVICARHAPGKPVEADGRTARFEPLD 61 Query 63 IRDEDSVKRLVGEIGERHGRLDMLVNNAGGSPYALAAEATHNFHRKIVELNVLAPLLVSQ 122 +RD D+V + HGRLD+LVNNAGGSPY L AEA ++VELN++AP+ VS Sbjct 62 VRDADAVAAFFDRLRRSHGRLDLLVNNAGGSPYGLIAEAGQRRAARVVELNLIAPMTVSL 121 Query 123 HANVLMQAQPNGGSIVNICSVSGRRPTPGTAAYGAAKAGLENLTTTLAVEWAPKVRVNAV 182 A LM+ Q GGSIV I SVSG RP+PGT YGAAKAGLENL TLAVEWAP VRVN + Sbjct 122 SAYELMRHQEGGGSIVMIGSVSGTRPSPGTGPYGAAKAGLENLARTLAVEWAPAVRVNTL 181 Query 183 VVGMVETERSELFYGDAESIARVAATVPLGRLARPADIGWAAAFLASDAASYISGATLEV 242 V+GMV TE S L YGD E IA V TVPLGRLA P + G A FLAS A YISGA++ + Sbjct 182 VLGMVRTELSHLHYGDEEGIAAVGRTVPLGRLAEPVEAGTACVFLASGLAEYISGASIAI 241 Query 243 HGGGEPPPYLGASSANK 259 HGGGE P +L A++ N+ Sbjct 242 HGGGERPAFLDAANVNQ 258 >gi|297198991|ref|ZP_06916388.1| 2-hydroxycyclohexanecarboxyl-CoA dehydrogenase [Streptomyces sviceus ATCC 29083] gi|197711087|gb|EDY55121.1| 2-hydroxycyclohexanecarboxyl-CoA dehydrogenase [Streptomyces sviceus ATCC 29083] Length=253 Score = 266 bits (681), Expect = 2e-69, Method: Compositional matrix adjust. Identities = 148/248 (60%), Positives = 178/248 (72%), Gaps = 8/248 (3%) Query 14 LAGRVVLVTGGVRGVGAGISSVFAEQGATVITCARRAVDGQ--PYEFHRCDIRDEDSVKR 71 L GRVV+VTGG RGVGAGI+ F E GA V+ CARR + F D+RD D+V+ Sbjct 3 LNGRVVVVTGGTRGVGAGIARSFTEAGAKVVVCARRPPEAPLPKARFVPLDVRDADAVRH 62 Query 72 LVGEIGERHGRLDMLVNNAGGSPYALAAEATHNFHRKIVELNVLAPLLVSQHANVLMQAQ 131 E+ RLD+LVNNAGG+PY L A+A H +++ELN+LAPL VS A + Sbjct 63 FFAELP----RLDVLVNNAGGAPYRLLADAGPERHLRVLELNLLAPLTVSLAA--YEHLK 116 Query 132 PNGGSIVNICSVSGRRPTPGTAAYGAAKAGLENLTTTLAVEWAPKVRVNAVVVGMVETER 191 GSIV I SVSG RP+PGTAAYGAAKAGLENL ++AVEWAP VRVN +VVGMV TE+ Sbjct 117 RTHGSIVMIGSVSGGRPSPGTAAYGAAKAGLENLARSMAVEWAPDVRVNTLVVGMVRTEQ 176 Query 192 SELFYGDAESIARVAATVPLGRLARPADIGWAAAFLASDAASYISGATLEVHGGGEPPPY 251 S+L YGD E IA V+ TVPLGRLA P+D+G AA FLASDAA+YISGA+L VHGGGE P + Sbjct 177 SQLHYGDEEGIAAVSRTVPLGRLAEPSDVGAAAVFLASDAAAYISGASLLVHGGGERPAF 236 Query 252 LGASSANK 259 L A++ NK Sbjct 237 LDAATVNK 244 >gi|311744252|ref|ZP_07718056.1| trans-2-enoyl-CoA reductase (NADPH) [Aeromicrobium marinum DSM 15272] gi|311312425|gb|EFQ82338.1| trans-2-enoyl-CoA reductase (NADPH) [Aeromicrobium marinum DSM 15272] Length=256 Score = 266 bits (679), Expect = 3e-69, Method: Compositional matrix adjust. Identities = 144/241 (60%), Positives = 184/241 (77%), Gaps = 2/241 (0%) Query 14 LAGRVVLVTGGVRGVGAGISSVFAEQGATVITCARRAVDGQ-PYEFHR-CDIRDEDSVKR 71 LAGRV LVTGG RG+G GI+ V + GATV+TC R VD P HR CD+RD ++V Sbjct 7 LAGRVALVTGGARGIGRGITEVLVDAGATVVTCGRSDVDDPVPGSEHRTCDVRDPEAVAA 66 Query 72 LVGEIGERHGRLDMLVNNAGGSPYALAAEATHNFHRKIVELNVLAPLLVSQHANVLMQAQ 131 LV I ERHGRLD+LVNNAGG+PYALAA+++ KI+ LN+ + L VS+ AN +MQ Q Sbjct 67 LVAGIVERHGRLDVLVNNAGGAPYALAADSSPRLDDKILGLNLSSVLTVSKAANAVMQRQ 126 Query 132 PNGGSIVNICSVSGRRPTPGTAAYGAAKAGLENLTTTLAVEWAPKVRVNAVVVGMVETER 191 P GG+IV+I SVS RP+PGTA+YGAAKAG ++LT +LAVEW P+VR+N++ VG+V TE+ Sbjct 127 PEGGAIVSISSVSALRPSPGTASYGAAKAGADSLTRSLAVEWGPRVRINSIDVGLVRTEQ 186 Query 192 SELFYGDAESIARVAATVPLGRLARPADIGWAAAFLASDAASYISGATLEVHGGGEPPPY 251 + YGD E++A V AT+PLGR+ARPA++G AFLASD ASY+SGAT+ HGGGEPP + Sbjct 187 TADHYGDDETVAAVEATIPLGRMARPAEVGRVVAFLASDLASYVSGATVACHGGGEPPVF 246 Query 252 L 252 L Sbjct 247 L 247 >gi|328881704|emb|CCA54943.1| Probable short-chain type dehydrogenase or reductase [Streptomyces venezuelae ATCC 10712] Length=263 Score = 265 bits (678), Expect = 4e-69, Method: Compositional matrix adjust. Identities = 144/251 (58%), Positives = 179/251 (72%), Gaps = 8/251 (3%) Query 14 LAGRVVLVTGGVRGVGAGISSVFAEQGATVITCARRAVD------GQPYEFHRCDIRDED 67 L GRVVLVTGG RGVGAGI+ F GA V CARR D G+ FH D+R+ Sbjct 3 LDGRVVLVTGGTRGVGAGITRAFLRAGAHVAVCARRPPDTPVQAAGRTAAFHPVDLREPT 62 Query 68 SVKRLVGEIGERHGRLDMLVNNAGGSPYALAAEATHNFHRKIVELNVLAPLLVSQHANVL 127 +V+ L+ + ER+GRLD+LVNNAGG+PY L E+ H ++VELN+ APL V+ A+ L Sbjct 63 AVQELLSTLAERYGRLDVLVNNAGGTPYRLLGESDAERHARVVELNLTAPLTVTLAAHPL 122 Query 128 MQAQPNGGSIVNICSVSGRRPTPGTAAYGAAKAGLENLTTTLAVEWAPKVRVNAVVVGMV 187 ++A G++V I SVSG RP+PGTAAYGAAKAGLENL ++AVEWAP++RVN +V+GMV Sbjct 123 LRAAR--GTVVMIGSVSGTRPSPGTAAYGAAKAGLENLARSMAVEWAPEIRVNTLVLGMV 180 Query 188 ETERSELFYGDAESIARVAATVPLGRLARPADIGWAAAFLASDAASYISGATLEVHGGGE 247 ETE S L YGD IA V TVPLGRLA P +IG AA FLAS A+Y+SGA+L VHGGGE Sbjct 181 ETEMSHLHYGDEAGIAAVGRTVPLGRLAAPDEIGEAAVFLASGRAAYVSGASLLVHGGGE 240 Query 248 PPPYLGASSAN 258 P +L A++ N Sbjct 241 RPAFLDAANVN 251 >gi|302533873|ref|ZP_07286215.1| 3-oxoacyl-[acyl-carrier-protein] reductase [Streptomyces sp. C] gi|302442768|gb|EFL14584.1| 3-oxoacyl-[acyl-carrier-protein] reductase [Streptomyces sp. C] Length=254 Score = 260 bits (664), Expect = 1e-67, Method: Compositional matrix adjust. Identities = 141/252 (56%), Positives = 175/252 (70%), Gaps = 8/252 (3%) Query 14 LAGRVVLVTGGVRGVGAGISSVFAEQGATVITCARR------AVDGQPYEFHRCDIRDED 67 L GRVV+VTGG RGVGAGI+ F GA V+ CARR A G+ F D+RD Sbjct 3 LNGRVVVVTGGTRGVGAGIARSFLTAGAEVVVCARRPPREPVAAAGRRAAFTAVDLRDAA 62 Query 68 SVKRLVGEIGERHGRLDMLVNNAGGSPYALAAEATHNFHRKIVELNVLAPLLVSQHANVL 127 SV+ +GERHGRLD LVNNAGG+PY L E H ++VELN++AP+ S A Sbjct 63 SVREFFDAVGERHGRLDCLVNNAGGTPYRLLGEGAAERHARVVELNLVAPMTASLAAYPW 122 Query 128 MQAQPNGGSIVNICSVSGRRPTPGTAAYGAAKAGLENLTTTLAVEWAPKVRVNAVVVGMV 187 ++ + GS+V + SVSG RP+PGTAAYGAAKAGLENL ++AVEWAP VRVN++V+GMV Sbjct 123 LR--ESRGSVVMVGSVSGTRPSPGTAAYGAAKAGLENLARSMAVEWAPDVRVNSLVLGMV 180 Query 188 ETERSELFYGDAESIARVAATVPLGRLARPADIGWAAAFLASDAASYISGATLEVHGGGE 247 TE + L YGD +A V ATVPLGRLA P+++G AA FLAS A Y+SGA+L VHGGGE Sbjct 181 RTELAHLHYGDEAGVAAVGATVPLGRLAEPSEVGEAAVFLASGRAGYVSGASLLVHGGGE 240 Query 248 PPPYLGASSANK 259 P +L A++ NK Sbjct 241 RPAFLDAATVNK 252 >gi|302548221|ref|ZP_07300563.1| short-chain dehydrogenase/reductase family oxidoreductase [Streptomyces hygroscopicus ATCC 53653] gi|302465839|gb|EFL28932.1| short-chain dehydrogenase/reductase family oxidoreductase [Streptomyces himastatinicus ATCC 53653] Length=272 Score = 258 bits (660), Expect = 5e-67, Method: Compositional matrix adjust. Identities = 140/253 (56%), Positives = 175/253 (70%), Gaps = 6/253 (2%) Query 9 AINFGLAGRVVLVTGGVRGVGAGISSVFAEQGATVITCARRAVD------GQPYEFHRCD 62 A++ L+GRV +VTGG RGVGAGI+ GA V+ CARR D G+ F D Sbjct 2 AVSIDLSGRVAVVTGGTRGVGAGIARALLAAGADVVVCARRPPDHPVAAAGRTARFRALD 61 Query 63 IRDEDSVKRLVGEIGERHGRLDMLVNNAGGSPYALAAEATHNFHRKIVELNVLAPLLVSQ 122 +RD +V + + HGRLD+LVNNAGGSPY L AE+ ++VELN++AP+ V+ Sbjct 62 VRDAFAVAEFFAWVRDAHGRLDVLVNNAGGSPYGLLAESGPRRAVRVVELNLIAPMTVAL 121 Query 123 HANVLMQAQPNGGSIVNICSVSGRRPTPGTAAYGAAKAGLENLTTTLAVEWAPKVRVNAV 182 A +M+ Q GGSIV I SVSG RP+PGTAAYGAAKAGL+NL TLAVEWAP +RVN + Sbjct 122 AAYEVMRDQEGGGSIVMIGSVSGTRPSPGTAAYGAAKAGLDNLARTLAVEWAPAIRVNTL 181 Query 183 VVGMVETERSELFYGDAESIARVAATVPLGRLARPADIGWAAAFLASDAASYISGATLEV 242 V+GMV TE + L YGDA +A V+ TVPLGRLA PA+ G A FLAS A+YI+GA+L V Sbjct 182 VLGMVHTELAHLHYGDATGVAAVSRTVPLGRLADPAEAGDACVFLASPMAAYITGASLAV 241 Query 243 HGGGEPPPYLGAS 255 HGGGE P +L A+ Sbjct 242 HGGGERPAFLAAA 254 >gi|294812052|ref|ZP_06770695.1| Short chain dehydrogenase [Streptomyces clavuligerus ATCC 27064] gi|326440555|ref|ZP_08215289.1| short chain dehydrogenase [Streptomyces clavuligerus ATCC 27064] gi|294324651|gb|EFG06294.1| Short chain dehydrogenase [Streptomyces clavuligerus ATCC 27064] Length=272 Score = 253 bits (647), Expect = 2e-65, Method: Compositional matrix adjust. Identities = 142/267 (54%), Positives = 177/267 (67%), Gaps = 24/267 (8%) Query 14 LAGRVVLVTGGVRGVGAGISSVFAEQGATVITCARRAVDGQ------------------- 54 L GRVV+VTGG RGVGAGI+ F GATV+ CARR D + Sbjct 3 LDGRVVVVTGGTRGVGAGIADAFLRAGATVLVCARRPPDPRAPGDASTAARSAREAARGC 62 Query 55 --PYEFHRCDIRDEDSVKRLVGEIGERHGRLDMLVNNAGGSPYALAAEATHNFHRKIVEL 112 PY FH D+RD +V+ + R+GRLD LVNNAGG+PY L A+ H ++VEL Sbjct 63 AGPY-FHPVDLRDPGAVEAFFALVARRYGRLDTLVNNAGGTPYRLLADGGAARHTRVVEL 121 Query 113 NVLAPLLVSQHANVLMQAQPNGGSIVNICSVSGRRPTPGTAAYGAAKAGLENLTTTLAVE 172 N+LAPL S A L++ GSIV + SVSG RP+PGTAAYGAAKAGL +L ++AVE Sbjct 122 NLLAPLTASLAAYPLLKRA--HGSIVMVGSVSGDRPSPGTAAYGAAKAGLASLARSMAVE 179 Query 173 WAPKVRVNAVVVGMVETERSELFYGDAESIARVAATVPLGRLARPADIGWAAAFLASDAA 232 WAP++RVN +V+GMV TE S L YGD E +A V TVPLGRLA P+D+G AA FLAS A Sbjct 180 WAPEIRVNTLVLGMVRTELSFLHYGDEEGVAAVGRTVPLGRLAEPSDVGGAALFLASPGA 239 Query 233 SYISGATLEVHGGGEPPPYLGASSANK 259 +YISGA L +HGGGE P +L A++A++ Sbjct 240 AYISGAALHLHGGGERPAFLDAATAHR 266 >gi|254393737|ref|ZP_05008858.1| short chain dehydrogenase [Streptomyces clavuligerus ATCC 27064] gi|197707345|gb|EDY53157.1| short chain dehydrogenase [Streptomyces clavuligerus ATCC 27064] Length=270 Score = 253 bits (645), Expect = 3e-65, Method: Compositional matrix adjust. Identities = 141/267 (53%), Positives = 177/267 (67%), Gaps = 24/267 (8%) Query 14 LAGRVVLVTGGVRGVGAGISSVFAEQGATVITCARRAVDGQ------------------- 54 + GRVV+VTGG RGVGAGI+ F GATV+ CARR D + Sbjct 1 MDGRVVVVTGGTRGVGAGIADAFLRAGATVLVCARRPPDPRAPGDASTAARSAREAARGC 60 Query 55 --PYEFHRCDIRDEDSVKRLVGEIGERHGRLDMLVNNAGGSPYALAAEATHNFHRKIVEL 112 PY FH D+RD +V+ + R+GRLD LVNNAGG+PY L A+ H ++VEL Sbjct 61 AGPY-FHPVDLRDPGAVEAFFALVARRYGRLDTLVNNAGGTPYRLLADGGAARHTRVVEL 119 Query 113 NVLAPLLVSQHANVLMQAQPNGGSIVNICSVSGRRPTPGTAAYGAAKAGLENLTTTLAVE 172 N+LAPL S A L++ GSIV + SVSG RP+PGTAAYGAAKAGL +L ++AVE Sbjct 120 NLLAPLTASLAAYPLLKRA--HGSIVMVGSVSGDRPSPGTAAYGAAKAGLASLARSMAVE 177 Query 173 WAPKVRVNAVVVGMVETERSELFYGDAESIARVAATVPLGRLARPADIGWAAAFLASDAA 232 WAP++RVN +V+GMV TE S L YGD E +A V TVPLGRLA P+D+G AA FLAS A Sbjct 178 WAPEIRVNTLVLGMVRTELSFLHYGDEEGVAAVGRTVPLGRLAEPSDVGGAALFLASPGA 237 Query 233 SYISGATLEVHGGGEPPPYLGASSANK 259 +YISGA L +HGGGE P +L A++A++ Sbjct 238 AYISGAALHLHGGGERPAFLDAATAHR 264 >gi|297155139|gb|ADI04851.1| short chain dehydrogenase [Streptomyces bingchenggensis BCW-1] Length=263 Score = 252 bits (643), Expect = 4e-65, Method: Compositional matrix adjust. Identities = 142/257 (56%), Positives = 172/257 (67%), Gaps = 6/257 (2%) Query 9 AINFGLAGRVVLVTGGVRGVGAGISSVFAEQGATVITCARRAVD------GQPYEFHRCD 62 A+ L+GRV +VTGG RGVGAGI+ GA V+ CARR D G+ F D Sbjct 2 AVTIDLSGRVAVVTGGTRGVGAGIARSLLTAGAEVVVCARRPGDRPVEAAGRAARFLPLD 61 Query 63 IRDEDSVKRLVGEIGERHGRLDMLVNNAGGSPYALAAEATHNFHRKIVELNVLAPLLVSQ 122 +RD D+V + +GRLD+LVNNAGGS + L A++ ++VELN++APL VS Sbjct 62 VRDADAVGAFFERLRGSYGRLDLLVNNAGGSRFGLLADSGPRRAARVVELNLIAPLTVSL 121 Query 123 HANVLMQAQPNGGSIVNICSVSGRRPTPGTAAYGAAKAGLENLTTTLAVEWAPKVRVNAV 182 A +M+ Q GGSIV I SVSG RP+PGTAAYGAAKAGL NL +LAVEWAP VRVN V Sbjct 122 AAYEVMRHQERGGSIVMIGSVSGTRPSPGTAAYGAAKAGLANLAHSLAVEWAPAVRVNTV 181 Query 183 VVGMVETERSELFYGDAESIARVAATVPLGRLARPADIGWAAAFLASDAASYISGATLEV 242 V+GMV TE S L YGD +A V TVPLGRLA P + G A FLASD A+YISGA L V Sbjct 182 VLGMVRTELSHLHYGDEAGLAAVGRTVPLGRLAEPDEAGDACVFLASDLAAYISGAALCV 241 Query 243 HGGGEPPPYLGASSANK 259 HGGGE P +L A++ N+ Sbjct 242 HGGGERPAFLDAANVNE 258 >gi|290961228|ref|YP_003492410.1| dehydrogenase [Streptomyces scabiei 87.22] gi|260650754|emb|CBG73870.1| putative dehydrogenase [Streptomyces scabiei 87.22] Length=270 Score = 248 bits (632), Expect = 8e-64, Method: Compositional matrix adjust. Identities = 137/248 (56%), Positives = 179/248 (73%), Gaps = 10/248 (4%) Query 14 LAGRVVLVTGGVRGVGAGISSVFAEQGATVITCARRA--VDGQPYEFHRCDIRDEDSVKR 71 L G++ +VTGG RG+GAGI+ FA+ GA V+TCARR V + EF D+RD D+V Sbjct 3 LDGKLAVVTGGTRGIGAGIARAFADAGAEVVTCARRPPEVPLKGAEFMPLDVRDPDAVHA 62 Query 72 LVGEIGERHGRLDMLVNNAGGSPYALAAEATHNFHRKIVELNVLAPLLVSQHANV-LMQA 130 + R+D+LVNNAGG+P+ A+A H +++ELN+ APL VS A+ L +A Sbjct 63 FFAGLP----RVDVLVNNAGGTPHRTLAQADARHHARVLELNLTAPLTVSLAAHAHLRRA 118 Query 131 QPNGGSIVNICSVSGRRPTPGTAAYGAAKAGLENLTTTLAVEWAPKVRVNAVVVGMVETE 190 + G+IV I SVSG RP+PG+AAYGAAKAGLE+L ++AVEWAP +RVN +V+GMV TE Sbjct 119 R---GAIVMIGSVSGSRPSPGSAAYGAAKAGLEHLARSMAVEWAPDIRVNTLVLGMVRTE 175 Query 191 RSELFYGDAESIARVAATVPLGRLARPADIGWAAAFLASDAASYISGATLEVHGGGEPPP 250 S L YGD + IA VA TVPLGRLA P+D+G AA FLASDAA+YI+GA+L VHGGGE P Sbjct 176 LSHLHYGDEQGIAAVARTVPLGRLATPSDVGDAAVFLASDAAAYITGASLHVHGGGERPA 235 Query 251 YLGASSAN 258 +L A++A+ Sbjct 236 FLDATTAD 243 >gi|302528346|ref|ZP_07280688.1| 2-hydroxycyclohexanecarboxyl-CoA dehydrogenase [Streptomyces sp. AA4] gi|302437241|gb|EFL09057.1| 2-hydroxycyclohexanecarboxyl-CoA dehydrogenase [Streptomyces sp. AA4] Length=256 Score = 246 bits (628), Expect = 3e-63, Method: Compositional matrix adjust. Identities = 136/249 (55%), Positives = 168/249 (68%), Gaps = 7/249 (2%) Query 10 INFGLAGRVVLVTGGVRGVGAGISSVFAEQGATVITCAR------RAVDGQPYEFHRCDI 63 ++F L RVVLVTGG RGVG GI + F E GA V C R R +G+ F + D+ Sbjct 3 VSFDLTDRVVLVTGGARGVGDGIVATFLEAGAEVEICGRTEPAKLREANGRKPRFTQVDV 62 Query 64 RDEDSVKRLVGEIGERHGRLDMLVNNAGGSPYALAAEATHNFHRKIVELNVLAPLLVSQH 123 R+ + V R + IGERHGRLD++VNNAGG+P+A AEA+ FHRKI ELN LA V Sbjct 63 REPEQVGRWLEGIGERHGRLDVVVNNAGGAPFAQFAEASPKFHRKINELNFLAAAYVLHA 122 Query 124 ANVLMQAQPNGGSIVNICSVSGRRPTPGTAAYGAAKAGLENLTTTLAVEWAPKVRVNAVV 183 A+ L++ P G S VN+ S+S RRP+PGTA YGAAKA LE+LTT+LAVEWAP+VRVNAV Sbjct 123 AHPLLRETP-GASAVNVTSISARRPSPGTAVYGAAKAALESLTTSLAVEWAPRVRVNAVS 181 Query 184 VGMVETERSELFYGDAESIARVAATVPLGRLARPADIGWAAAFLASDAASYISGATLEVH 243 G+VET SE YGD VA T+P G+ A PA++G A LAS AS++SGA L V Sbjct 182 CGLVETPGSEDHYGDPAQRDAVARTIPRGQFASPAEVGQACLLLASPLASHVSGAVLNVD 241 Query 244 GGGEPPPYL 252 GGGE P +L Sbjct 242 GGGEWPAFL 250 >gi|302549254|ref|ZP_07301596.1| 2-hydroxycyclohexanecarboxyl-CoA dehydrogenase [Streptomyces viridochromogenes DSM 40736] gi|302466872|gb|EFL29965.1| 2-hydroxycyclohexanecarboxyl-CoA dehydrogenase [Streptomyces viridochromogenes DSM 40736] Length=258 Score = 245 bits (626), Expect = 4e-63, Method: Compositional matrix adjust. Identities = 142/253 (57%), Positives = 176/253 (70%), Gaps = 8/253 (3%) Query 14 LAGRVVLVTGGVRGVGAGISSVFAEQGATVITCARRAVDGQPYE-------FHRCDIRDE 66 L+GRV +VTGG RGVGAGI+ E GA V+TCARR D +P E F ++RD Sbjct 7 LSGRVAVVTGGTRGVGAGITRALLEAGAEVVTCARRPPD-EPVEAACRAARFLPVELRDA 65 Query 67 DSVKRLVGEIGERHGRLDMLVNNAGGSPYALAAEATHNFHRKIVELNVLAPLLVSQHANV 126 D+V ++ + +GRLD+LVNNAGG+PY L E H ++VELN+LAPL S A Sbjct 66 DAVGAFFAQVSDEYGRLDILVNNAGGTPYRLLEEGGAARHSRVVELNLLAPLAASLAAYE 125 Query 127 LMQAQPNGGSIVNICSVSGRRPTPGTAAYGAAKAGLENLTTTLAVEWAPKVRVNAVVVGM 186 M+ QP GGSIV I SVSG RP+PG+AAYGAAKAGLE L ++AVEWAP+VRVN VV+GM Sbjct 126 QMRRQPGGGSIVMIGSVSGSRPSPGSAAYGAAKAGLEQLARSMAVEWAPQVRVNTVVLGM 185 Query 187 VETERSELFYGDAESIARVAATVPLGRLARPADIGWAAAFLASDAASYISGATLEVHGGG 246 V TE + L YGD + V TVPLGRLA PA++G A FLAS+ A+YISGA+L VHGGG Sbjct 186 VRTELAHLHYGDDSGVEAVGRTVPLGRLADPAEVGDACVFLASERAAYISGASLLVHGGG 245 Query 247 EPPPYLGASSANK 259 E P +L A++A Sbjct 246 ERPAFLDAATAGN 258 >gi|254481390|ref|ZP_05094635.1| oxidoreductase, short chain dehydrogenase/reductase family [marine gamma proteobacterium HTCC2148] gi|214038553|gb|EEB79215.1| oxidoreductase, short chain dehydrogenase/reductase family [marine gamma proteobacterium HTCC2148] Length=254 Score = 240 bits (613), Expect = 1e-61, Method: Compositional matrix adjust. Identities = 132/250 (53%), Positives = 172/250 (69%), Gaps = 6/250 (2%) Query 16 GRVVLVTGGVRGVGAGISSVFAEQGATVITCARRAVDGQPYE------FHRCDIRDEDSV 69 G+ ++VTGG +G+G GIS F GA V+ C R + P F CD+++ + + Sbjct 5 GKAIIVTGGGKGIGRGISERFLAAGAKVLICGRSEPESLPSAGGRQALFIACDVKNFEQI 64 Query 70 KRLVGEIGERHGRLDMLVNNAGGSPYALAAEATHNFHRKIVELNVLAPLLVSQHANVLMQ 129 + V + GRLD+LVNNAGG+P+A AAE + F I+ LN++APL SQ AN +MQ Sbjct 65 EACVDYAVAQFGRLDVLVNNAGGAPHADAAEVSPRFSESIIRLNLIAPLNFSQAANRIMQ 124 Query 130 AQPNGGSIVNICSVSGRRPTPGTAAYGAAKAGLENLTTTLAVEWAPKVRVNAVVVGMVET 189 Q +GGSI+NI SVS RP+PGTAAYGAAKAGL NL ++LAVEWAPKVRVNA++VG+ T Sbjct 125 TQESGGSIINIASVSTLRPSPGTAAYGAAKAGLVNLGSSLAVEWAPKVRVNAIIVGLTRT 184 Query 190 ERSELFYGDAESIARVAATVPLGRLARPADIGWAAAFLASDAASYISGATLEVHGGGEPP 249 E+S L YGD IA V AT+P+GR+A P DIG A FLAS ASY+SG + VHGGGE P Sbjct 185 EQSHLHYGDEHGIAAVEATIPMGRMAVPEDIGDACLFLASSLASYVSGTSFAVHGGGEKP 244 Query 250 PYLGASSANK 259 +L A+S ++ Sbjct 245 AFLDAASPDQ 254 >gi|77359832|ref|YP_339407.1| short chain dehydrogenase [Pseudoalteromonas haloplanktis TAC125] gi|76874743|emb|CAI85964.1| putative 3-oxoacyl-[acyl-carrier-protein] reductase [Pseudoalteromonas haloplanktis TAC125] Length=260 Score = 240 bits (613), Expect = 1e-61, Method: Compositional matrix adjust. Identities = 128/252 (51%), Positives = 166/252 (66%), Gaps = 11/252 (4%) Query 17 RVVLVTGGVRGVGAGISSVFAEQGATVITCARRAVDGQPY----------EFHRCDIRDE 66 +VVL+TGG +G+G GI+ F GA V+ C R V+ P F + D++D Sbjct 10 KVVLITGGTKGIGLGIAQGFLSAGAKVVVCGREQVEQLPQVILDGKTRQAHFIQADVKDI 69 Query 67 DSVKRLVGEIGERHGRLDMLVNNAGGSPYALAAEATHNFHRKIVELNVLAPLLVSQHANV 126 DS + I + +G LD+L+NNAGGSP+ALA +A+ FH I++LN++APL V+Q AN Sbjct 70 DSTAAMFSTIVKEYGTLDVLINNAGGSPFALADKASPRFHEAILKLNLIAPLNVAQQANE 129 Query 127 LMQAQPNGGSIVNICSVSGRRPTPGTAAYGAAKAGLENLTTTLAVEWAPKVRVNAVVVGM 186 +MQA N G I+ I S+S R +PGTAAYGAAKAG+ +L +LAVEWAPKVRV AV G+ Sbjct 130 IMQAN-NSGCIIFIGSISAMRASPGTAAYGAAKAGILSLVKSLAVEWAPKVRVVAVSPGL 188 Query 187 VETERSELFYGDAESIARVAATVPLGRLARPADIGWAAAFLASDAASYISGATLEVHGGG 246 V TE S L YGD IA V+AT+P GR+A+P DI A FLAS ASY SG L ++GGG Sbjct 189 VHTENSHLHYGDEAGIAAVSATIPAGRMAQPDDIANACLFLASAEASYASGCNLLLNGGG 248 Query 247 EPPPYLGASSAN 258 E P +L AS N Sbjct 249 EMPAFLSASETN 260 >gi|271963598|ref|YP_003337794.1| short chain dehydrogenase [Streptosporangium roseum DSM 43021] gi|270506773|gb|ACZ85051.1| short chain dehydrogenase [Streptosporangium roseum DSM 43021] Length=251 Score = 239 bits (610), Expect = 3e-61, Method: Compositional matrix adjust. Identities = 130/244 (54%), Positives = 165/244 (68%), Gaps = 6/244 (2%) Query 10 INFGLAGRVVLVTGGVRGVGAGISSVFAEQGATVITCARRAVDGQP--YEFHRCDIRDED 67 I++ AG VVLVTGG +G+GAGI+ F GA V+ CAR+ P F D+RD Sbjct 3 ISYDYAGSVVLVTGGTKGLGAGIAGAFLAAGAQVVVCARKEPSALPAGVGFVAADVRDPA 62 Query 68 SVKRLVGEIGERHGRLDMLVNNAGGSPYALAAEATHNFHRKIVELNVLAPLLVSQHANVL 127 V R++GEI ERHGRLD +VNNAGGSPYA A + H +IVELN+ APLLV+Q A+ L Sbjct 63 EVDRMIGEIEERHGRLDTVVNNAGGSPYAPLAGTSPRLHARIVELNLTAPLLVAQRAHPL 122 Query 128 MQAQPNGGSIVNICSVSGRRPTPGTAAYGAAKAGLENLTTTLAVEWAPKVRVNAVVVGMV 187 + A GGS+V I S SG RP+PGT+AYGAAKAGL +L LA EWAP+VRVN VVVG+ Sbjct 123 LDAA--GGSVVMIGSSSGTRPSPGTSAYGAAKAGLHHLAACLAAEWAPRVRVNTVVVGLA 180 Query 188 ETERSELFYGDAESIARVAATVPLGRLARPADIGWAAAFLASDAASYISGATLEVHGGGE 247 ETE + YG E + R+ AT+P GR+A P D+ A +LA A Y++GA + +HGGGE Sbjct 181 ETESAAGHYGGPEGVRRMGATIPAGRMALPGDVAGACLWLA--APGYVTGAEILLHGGGE 238 Query 248 PPPY 251 P + Sbjct 239 IPAW 242 >gi|29832746|ref|NP_827380.1| short chain dehydrogenase [Streptomyces avermitilis MA-4680] gi|29609866|dbj|BAC73915.1| putative dehydrogenase [Streptomyces avermitilis MA-4680] Length=276 Score = 238 bits (606), Expect = 8e-61, Method: Compositional matrix adjust. Identities = 141/248 (57%), Positives = 180/248 (73%), Gaps = 8/248 (3%) Query 14 LAGRVVLVTGGVRGVGAGISSVFAEQGATVITCARRA--VDGQPYEFHRCDIRDEDSVKR 71 L G+V +VTGG RGVGAGI+ FA GA V+ CARR V + EF R D+RD D+V Sbjct 3 LNGKVAVVTGGTRGVGAGIARAFAAAGAEVVVCARRPPEVLLKGAEFARLDLRDPDAVGA 62 Query 72 LVGEIGERHGRLDMLVNNAGGSPYALAAEATHNFHRKIVELNVLAPLLVSQHANVLMQAQ 131 G + RLD+LVNNAGG+PY A+ H ++VELN++APL S A ++ Sbjct 63 FFGALP----RLDVLVNNAGGTPYRRLADVDAARHARVVELNLVAPLTASLAAYEHLKRA 118 Query 132 PNGGSIVNICSVSGRRPTPGTAAYGAAKAGLENLTTTLAVEWAPKVRVNAVVVGMVETER 191 GG++V + SVSG RP+PG+AAYGAAKAGLE+L ++AVEWAP++RVN +V+GMV TE Sbjct 119 --GGAVVMVGSVSGGRPSPGSAAYGAAKAGLESLARSMAVEWAPEIRVNTLVLGMVRTEL 176 Query 192 SELFYGDAESIARVAATVPLGRLARPADIGWAAAFLASDAASYISGATLEVHGGGEPPPY 251 S L YG AE +A V+ TVPLGRLA P+D+G AA FLASDAA+YISGA+L VHGGGEPP + Sbjct 177 SHLHYGGAEGVAAVSRTVPLGRLAEPSDVGAAAVFLASDAAAYISGASLLVHGGGEPPAF 236 Query 252 LGASSANK 259 LGA++AN+ Sbjct 237 LGAATANR 244 >gi|254387109|ref|ZP_05002382.1| short chain dehydrogenase [Streptomyces sp. Mg1] gi|194345927|gb|EDX26893.1| short chain dehydrogenase [Streptomyces sp. Mg1] Length=258 Score = 236 bits (601), Expect = 3e-60, Method: Compositional matrix adjust. Identities = 128/236 (55%), Positives = 161/236 (69%), Gaps = 8/236 (3%) Query 30 AGISSVFAEQGATVITCARR------AVDGQPYEFHRCDIRDEDSVKRLVGEIGERHGRL 83 AGI+ F GA V+ CARR A G+ F D+RD +V+ + RHGRL Sbjct 19 AGIARSFLAAGAEVVVCARRPPREPVAAAGRAASFTALDLRDPAAVRDFFAAVAARHGRL 78 Query 84 DMLVNNAGGSPYALAAEATHNFHRKIVELNVLAPLLVSQHANVLMQAQPNGGSIVNICSV 143 D LVNNAGG+PY L E H ++VELN+LAPL S A ++ + GS+V I SV Sbjct 79 DCLVNNAGGTPYRLLGEGEAERHARVVELNLLAPLTASLAAYPWLRE--SRGSVVMIGSV 136 Query 144 SGRRPTPGTAAYGAAKAGLENLTTTLAVEWAPKVRVNAVVVGMVETERSELFYGDAESIA 203 SG RP+PGTAAYGAAKAGLENL ++AVEWAP+VRVN++V+GMV TE + L YGD IA Sbjct 137 SGTRPSPGTAAYGAAKAGLENLARSMAVEWAPRVRVNSLVLGMVRTELAHLHYGDEAGIA 196 Query 204 RVAATVPLGRLARPADIGWAAAFLASDAASYISGATLEVHGGGEPPPYLGASSANK 259 V ATVPLGRLA P+++G AA FLASD A Y+SGA+L +HGGGE P +L A++ N+ Sbjct 197 AVGATVPLGRLAEPSEVGEAAVFLASDRAGYVSGASLLLHGGGERPAFLDAATVNQ 252 >gi|256390586|ref|YP_003112150.1| short chain dehydrogenase [Catenulispora acidiphila DSM 44928] gi|256356812|gb|ACU70309.1| short-chain dehydrogenase/reductase SDR [Catenulispora acidiphila DSM 44928] Length=256 Score = 234 bits (598), Expect = 7e-60, Method: Compositional matrix adjust. Identities = 140/253 (56%), Positives = 169/253 (67%), Gaps = 5/253 (1%) Query 9 AINFGLAGRVVLVTGGVRGVGAGISSVFAEQGATVITCARRAVDGQPY----EFHRCDIR 64 A+ L GRV LVTGG RGVG G+ S GA V++C R D P E D+R Sbjct 2 ALTLDLTGRVALVTGGARGVGRGVVSRLLAAGALVVSCGRTVPD-PPLPDGAEHRTADVR 60 Query 65 DEDSVKRLVGEIGERHGRLDMLVNNAGGSPYALAAEATHNFHRKIVELNVLAPLLVSQHA 124 D D V+ LV + HG LD++VNNAGG+PYALAAEA+ F IV LN+LAPL V+Q A Sbjct 61 DADQVRDLVEGVVADHGHLDLVVNNAGGAPYALAAEASPRFSAAIVGLNLLAPLTVAQEA 120 Query 125 NVLMQAQPNGGSIVNICSVSGRRPTPGTAAYGAAKAGLENLTTTLAVEWAPKVRVNAVVV 184 N +MQ Q GG I+NI S S RR +PGTAAYGAAKAGLENLT TLAVEWAP+VRVNA+ V Sbjct 121 NRVMQRQEGGGHIINISSESARRASPGTAAYGAAKAGLENLTRTLAVEWAPRVRVNAITV 180 Query 185 GMVETERSELFYGDAESIARVAATVPLGRLARPADIGWAAAFLASDAASYISGATLEVHG 244 G V TE+S L YGD +A VA T+ LGRLA P D+G LAS ASY++G + + G Sbjct 181 GPVRTEQSHLHYGDEAGLAAVARTIALGRLAEPEDVGDLCVLLASPFASYLTGTAILLDG 240 Query 245 GGEPPPYLGASSA 257 GG P +L A++A Sbjct 241 GGTRPAFLDAANA 253 >gi|339321863|ref|YP_004680757.1| 2,6-dioxo-6-phenylhexa-3-enoate hydrolase BphD [Cupriavidus necator N-1] gi|338168472|gb|AEI79526.1| 2,6-dioxo-6-phenylhexa-3-enoate hydrolase BphD [Cupriavidus necator N-1] Length=268 Score = 232 bits (591), Expect = 5e-59, Method: Compositional matrix adjust. Identities = 128/258 (50%), Positives = 164/258 (64%), Gaps = 10/258 (3%) Query 12 FGLAGRVVLVTGGVRGVGAGISSVFAEQGATVITCARRA---------VDGQPYEFHRCD 62 F G+ VLVTGG+RG+G I F GA V C R A DG+ F D Sbjct 10 FNYTGQTVLVTGGMRGIGRAIGEAFLRAGAQVFVCGRTAPADDSELPAADGRSARFIPAD 69 Query 63 IRDEDSVKRLVGEIGERHGRLDMLVNNAGGSPYALAAEATHNFHRKIVELNVLAPLLVSQ 122 IRD + ++ +I + LD++++NAGGSP+AL AEA+ ++ LN++APL ++Q Sbjct 70 IRDIEQADAMLAQIAQASPTLDVVIHNAGGSPFALVAEASPRLLESVIRLNLVAPLQLAQ 129 Query 123 HANVLMQAQPNGGSIVNICSVSGRRPTPGTAAYGAAKAGLENLTTTLAVEWAPKVRVNAV 182 AN MQ Q GG+ + + SVS RP+PGTAAYGAAKAG+ N TLAVEWAPKVRV AV Sbjct 130 RANARMQQQAGGGTQLFVGSVSALRPSPGTAAYGAAKAGILNAVRTLAVEWAPKVRVAAV 189 Query 183 VVGMVETERS-ELFYGDAESIARVAATVPLGRLARPADIGWAAAFLASDAASYISGATLE 241 GMV T+ S + YGD E++ +AATVPLGRLA P DI A FLAS ASY+SGA L Sbjct 190 SPGMVLTDTSQQQHYGDPEALRTMAATVPLGRLAHPDDIAGACLFLASPQASYVSGANLV 249 Query 242 VHGGGEPPPYLGASSANK 259 + GGGE P +L A+S N+ Sbjct 250 IDGGGERPAFLNAASLNR 267 Lambda K H 0.317 0.133 0.385 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 382276364284 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40