BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv3561 Length=507 Score E Sequences producing significant alignments: (Bits) Value gi|15610697|ref|NP_218078.1| long-chain-fatty-acid--CoA ligase [... 1015 0.0 gi|339296380|gb|AEJ48491.1| long-chain-fatty-acid-CoA ligase [My... 1013 0.0 gi|31794737|ref|NP_857230.1| acyl-CoA synthetase [Mycobacterium ... 1013 0.0 gi|15843173|ref|NP_338210.1| long-chain-fatty-acid--CoA ligase [... 1002 0.0 gi|340628525|ref|YP_004746977.1| putative fatty-acid-CoA ligase ... 954 0.0 gi|342862390|ref|ZP_08719030.1| long-chain-fatty-acid--CoA ligas... 853 0.0 gi|118619306|ref|YP_907638.1| acyl-CoA synthetase [Mycobacterium... 838 0.0 gi|240169776|ref|ZP_04748435.1| acyl-CoA synthetase [Mycobacteri... 835 0.0 gi|336458500|gb|EGO37473.1| acyl-CoA synthetase (AMP-forming)/AM... 827 0.0 gi|183985018|ref|YP_001853309.1| fatty-acid-CoA ligase FadD3 [My... 825 0.0 gi|118466679|ref|YP_879880.1| long-chain-fatty-acid--CoA ligase ... 821 0.0 gi|254773557|ref|ZP_05215073.1| long-chain-fatty-acid--CoA ligas... 820 0.0 gi|254822643|ref|ZP_05227644.1| long-chain-fatty-acid--CoA ligas... 811 0.0 gi|296166606|ref|ZP_06849035.1| substrate-CoA ligase [Mycobacter... 802 0.0 gi|120406234|ref|YP_956063.1| long-chain-fatty-acid--CoA ligase ... 784 0.0 gi|116266962|gb|ABJ96327.1| putative fatty-acid CoA synthetase [... 774 0.0 gi|108801657|ref|YP_641854.1| long-chain-fatty-acid--CoA ligase ... 769 0.0 gi|145222072|ref|YP_001132750.1| long-chain-fatty-acid--CoA liga... 764 0.0 gi|333992357|ref|YP_004524971.1| fatty-acid-CoA ligase [Mycobact... 720 0.0 gi|289752274|ref|ZP_06511652.1| fatty-acid-CoA ligase fadD3 [Myc... 713 0.0 gi|169627699|ref|YP_001701348.1| fatty-acid-CoA ligase FadD [Myc... 667 0.0 gi|289571803|ref|ZP_06452030.1| fatty-acid-CoA ligase fadD3 [Myc... 656 0.0 gi|41406604|ref|NP_959440.1| acyl-CoA synthase [Mycobacterium av... 621 7e-176 gi|54022447|ref|YP_116689.1| long-chain-fatty-acid--CoA ligase [... 586 3e-165 gi|111021567|ref|YP_704539.1| CoA ligase [Rhodococcus jostii RHA... 582 6e-164 gi|343924359|ref|ZP_08763909.1| putative fatty-acid--CoA ligase ... 575 6e-162 gi|226363950|ref|YP_002781732.1| fatty-acid--CoA ligase [Rhodoco... 575 8e-162 gi|262203852|ref|YP_003275060.1| AMP-dependent synthetase and li... 561 9e-158 gi|226304379|ref|YP_002764337.1| fatty-acid--CoA ligase [Rhodoco... 561 9e-158 gi|229494537|ref|ZP_04388300.1| putative fatty-acid-coa ligase f... 560 3e-157 gi|326384061|ref|ZP_08205744.1| long-chain-fatty-acid--CoA ligas... 558 1e-156 gi|333918615|ref|YP_004492196.1| CoA ligase [Amycolicicoccus sub... 551 1e-154 gi|319947747|ref|ZP_08021953.1| AMP-dependent synthetase and lig... 535 5e-150 gi|312138168|ref|YP_004005504.1| acyl-CoA ligase/synthetase [Rho... 529 5e-148 gi|325674928|ref|ZP_08154615.1| CoA ligase [Rhodococcus equi ATC... 529 5e-148 gi|300785282|ref|YP_003765573.1| acyl-CoA synthetase [Amycolatop... 517 1e-144 gi|296141507|ref|YP_003648750.1| AMP-dependent synthetase and li... 517 2e-144 gi|159038431|ref|YP_001537684.1| AMP-dependent synthetase and li... 513 2e-143 gi|145595185|ref|YP_001159482.1| AMP-dependent synthetase and li... 509 5e-142 gi|337766351|emb|CCB75062.1| Acyl-CoA synthetase [Streptomyces c... 507 2e-141 gi|328883144|emb|CCA56383.1| Long-chain-fatty-acid--CoA ligase [... 499 3e-139 gi|284043819|ref|YP_003394159.1| AMP-dependent synthetase and li... 499 6e-139 gi|119716992|ref|YP_923957.1| AMP-dependent synthetase and ligas... 496 3e-138 gi|29830349|ref|NP_824983.1| long-chain-fatty-acid--CoA ligase [... 488 8e-136 gi|302552183|ref|ZP_07304525.1| O-succinylbenzoate-CoA ligase [S... 488 1e-135 gi|326777403|ref|ZP_08236668.1| Long-chain-fatty-acid--CoA ligas... 488 1e-135 gi|291446923|ref|ZP_06586313.1| acyl-CoA synthetase [Streptomyce... 486 4e-135 gi|239989906|ref|ZP_04710570.1| acyl-CoA synthetase [Streptomyce... 486 5e-135 gi|290959588|ref|YP_003490770.1| AMP-binding protein [Streptomyc... 486 5e-135 gi|182436807|ref|YP_001824526.1| acyl-CoA synthetase [Streptomyc... 484 1e-134 >gi|15610697|ref|NP_218078.1| long-chain-fatty-acid--CoA ligase [Mycobacterium tuberculosis H37Rv] gi|148663424|ref|YP_001284947.1| acyl-CoA synthetase [Mycobacterium tuberculosis H37Ra] gi|148824767|ref|YP_001289521.1| acyl-CoA synthetase [Mycobacterium tuberculosis F11] 57 more sequence titles Length=507 Score = 1015 bits (2624), Expect = 0.0, Method: Compositional matrix adjust. Identities = 506/507 (99%), Positives = 507/507 (100%), Gaps = 0/507 (0%) Query 1 LINDLRTVPAALDRLVRQLPDHTALIAEDRRFTSTELRDAVYGAAAALIALGVEPADRVA 60 +INDLRTVPAALDRLVRQLPDHTALIAEDRRFTSTELRDAVYGAAAALIALGVEPADRVA Sbjct 1 MINDLRTVPAALDRLVRQLPDHTALIAEDRRFTSTELRDAVYGAAAALIALGVEPADRVA 60 Query 61 IWSPNTWHWVVACLAIHHAGAAVVPLNTRYTATEATDILDRAGAPVLFAAGLFLGADRAA 120 IWSPNTWHWVVACLAIHHAGAAVVPLNTRYTATEATDILDRAGAPVLFAAGLFLGADRAA Sbjct 61 IWSPNTWHWVVACLAIHHAGAAVVPLNTRYTATEATDILDRAGAPVLFAAGLFLGADRAA 120 Query 121 GLDRAALPALRHVVRVPVEADDGTWDEFIATGAGALDAVAARAAAVAPQDVSDILFTSGT 180 GLDRAALPALRHVVRVPVEADDGTWDEFIATGAGALDAVAARAAAVAPQDVSDILFTSGT Sbjct 121 GLDRAALPALRHVVRVPVEADDGTWDEFIATGAGALDAVAARAAAVAPQDVSDILFTSGT 180 Query 181 TGRSKGVLCAHRQSLSASASWAANGKITSDDRYLCINPFFHNFGYKAGILACLQTGATLI 240 TGRSKGVLCAHRQSLSASASWAANGKITSDDRYLCINPFFHNFGYKAGILACLQTGATLI Sbjct 181 TGRSKGVLCAHRQSLSASASWAANGKITSDDRYLCINPFFHNFGYKAGILACLQTGATLI 240 Query 241 PHVTFDPLHALRAIERHRITVLPGPPTIYQSLLDHPARKDFDLSSLRFAVTGAATVPVVL 300 PHVTFDPLHALRAIERHRITVLPGPPTIYQSLLDHPARKDFDLSSLRFAVTGAATVPVVL Sbjct 241 PHVTFDPLHALRAIERHRITVLPGPPTIYQSLLDHPARKDFDLSSLRFAVTGAATVPVVL 300 Query 301 VERMQSELDIDIVLTAYGLTEANGMGTMCRPEDDAVTVATTCGRPFADFELRIADDGEVL 360 VERMQSELDIDIVLTAYGLTEANGMGTMCRPEDDAVTVATTCGRPFADFELRIADDGEVL Sbjct 301 VERMQSELDIDIVLTAYGLTEANGMGTMCRPEDDAVTVATTCGRPFADFELRIADDGEVL 360 Query 361 LRGPNVMVGYLDDTEATAAAIDADGWLHTGDIGAVDQAGNLRITDRLKDMYICGGFNVYP 420 LRGPNVMVGYLDDTEATAAAIDADGWLHTGDIGAVDQAGNLRITDRLKDMYICGGFNVYP Sbjct 361 LRGPNVMVGYLDDTEATAAAIDADGWLHTGDIGAVDQAGNLRITDRLKDMYICGGFNVYP 420 Query 421 AEVEQVLARMDGVADAAVIGVPDQRLGEVGRAFVVARPGTGLDEASVIAYTREHLANFKT 480 AEVEQVLARMDGVADAAVIGVPDQRLGEVGRAFVVARPGTGLDEASVIAYTREHLANFKT Sbjct 421 AEVEQVLARMDGVADAAVIGVPDQRLGEVGRAFVVARPGTGLDEASVIAYTREHLANFKT 480 Query 481 PRSVRFVDVLPRNAAGKVSKPQLRELG 507 PRSVRFVDVLPRNAAGKVSKPQLRELG Sbjct 481 PRSVRFVDVLPRNAAGKVSKPQLRELG 507 >gi|339296380|gb|AEJ48491.1| long-chain-fatty-acid-CoA ligase [Mycobacterium tuberculosis CCDC5079] Length=507 Score = 1013 bits (2620), Expect = 0.0, Method: Compositional matrix adjust. Identities = 505/507 (99%), Positives = 506/507 (99%), Gaps = 0/507 (0%) Query 1 LINDLRTVPAALDRLVRQLPDHTALIAEDRRFTSTELRDAVYGAAAALIALGVEPADRVA 60 +INDLRTVPAALDRLVRQLPDHTALIAEDRRFTSTELRDAVYGAAAALIALGVEPADRVA Sbjct 1 MINDLRTVPAALDRLVRQLPDHTALIAEDRRFTSTELRDAVYGAAAALIALGVEPADRVA 60 Query 61 IWSPNTWHWVVACLAIHHAGAAVVPLNTRYTATEATDILDRAGAPVLFAAGLFLGADRAA 120 IWSPNTWHWVVACLA HHAGAAVVPLNTRYTATEATDILDRAGAPVLFAAGLFLGADRAA Sbjct 61 IWSPNTWHWVVACLASHHAGAAVVPLNTRYTATEATDILDRAGAPVLFAAGLFLGADRAA 120 Query 121 GLDRAALPALRHVVRVPVEADDGTWDEFIATGAGALDAVAARAAAVAPQDVSDILFTSGT 180 GLDRAALPALRHVVRVPVEADDGTWDEFIATGAGALDAVAARAAAVAPQDVSDILFTSGT Sbjct 121 GLDRAALPALRHVVRVPVEADDGTWDEFIATGAGALDAVAARAAAVAPQDVSDILFTSGT 180 Query 181 TGRSKGVLCAHRQSLSASASWAANGKITSDDRYLCINPFFHNFGYKAGILACLQTGATLI 240 TGRSKGVLCAHRQSLSASASWAANGKITSDDRYLCINPFFHNFGYKAGILACLQTGATLI Sbjct 181 TGRSKGVLCAHRQSLSASASWAANGKITSDDRYLCINPFFHNFGYKAGILACLQTGATLI 240 Query 241 PHVTFDPLHALRAIERHRITVLPGPPTIYQSLLDHPARKDFDLSSLRFAVTGAATVPVVL 300 PHVTFDPLHALRAIERHRITVLPGPPTIYQSLLDHPARKDFDLSSLRFAVTGAATVPVVL Sbjct 241 PHVTFDPLHALRAIERHRITVLPGPPTIYQSLLDHPARKDFDLSSLRFAVTGAATVPVVL 300 Query 301 VERMQSELDIDIVLTAYGLTEANGMGTMCRPEDDAVTVATTCGRPFADFELRIADDGEVL 360 VERMQSELDIDIVLTAYGLTEANGMGTMCRPEDDAVTVATTCGRPFADFELRIADDGEVL Sbjct 301 VERMQSELDIDIVLTAYGLTEANGMGTMCRPEDDAVTVATTCGRPFADFELRIADDGEVL 360 Query 361 LRGPNVMVGYLDDTEATAAAIDADGWLHTGDIGAVDQAGNLRITDRLKDMYICGGFNVYP 420 LRGPNVMVGYLDDTEATAAAIDADGWLHTGDIGAVDQAGNLRITDRLKDMYICGGFNVYP Sbjct 361 LRGPNVMVGYLDDTEATAAAIDADGWLHTGDIGAVDQAGNLRITDRLKDMYICGGFNVYP 420 Query 421 AEVEQVLARMDGVADAAVIGVPDQRLGEVGRAFVVARPGTGLDEASVIAYTREHLANFKT 480 AEVEQVLARMDGVADAAVIGVPDQRLGEVGRAFVVARPGTGLDEASVIAYTREHLANFKT Sbjct 421 AEVEQVLARMDGVADAAVIGVPDQRLGEVGRAFVVARPGTGLDEASVIAYTREHLANFKT 480 Query 481 PRSVRFVDVLPRNAAGKVSKPQLRELG 507 PRSVRFVDVLPRNAAGKVSKPQLRELG Sbjct 481 PRSVRFVDVLPRNAAGKVSKPQLRELG 507 >gi|31794737|ref|NP_857230.1| acyl-CoA synthetase [Mycobacterium bovis AF2122/97] gi|121639480|ref|YP_979704.1| acyl-CoA synthetase [Mycobacterium bovis BCG str. Pasteur 1173P2] gi|224991977|ref|YP_002646666.1| acyl-CoA synthetase [Mycobacterium bovis BCG str. Tokyo 172] 8 more sequence titles Length=507 Score = 1013 bits (2618), Expect = 0.0, Method: Compositional matrix adjust. Identities = 505/507 (99%), Positives = 506/507 (99%), Gaps = 0/507 (0%) Query 1 LINDLRTVPAALDRLVRQLPDHTALIAEDRRFTSTELRDAVYGAAAALIALGVEPADRVA 60 +INDLRTVPAALDRLVRQLPDHTALIAEDRRFTSTELRDAVYGAAAALIALGVEPADRVA Sbjct 1 MINDLRTVPAALDRLVRQLPDHTALIAEDRRFTSTELRDAVYGAAAALIALGVEPADRVA 60 Query 61 IWSPNTWHWVVACLAIHHAGAAVVPLNTRYTATEATDILDRAGAPVLFAAGLFLGADRAA 120 IWSPNTWHWVVACLAIHHAGAAVVPLNTRYTATEATDILDRAGAPVLFAAGLFLGADRAA Sbjct 61 IWSPNTWHWVVACLAIHHAGAAVVPLNTRYTATEATDILDRAGAPVLFAAGLFLGADRAA 120 Query 121 GLDRAALPALRHVVRVPVEADDGTWDEFIATGAGALDAVAARAAAVAPQDVSDILFTSGT 180 GLDRAALPALRHVVRVPVEADDGTWDEFIATGAGALDAVAARAAAVAPQDVSDILFTSGT Sbjct 121 GLDRAALPALRHVVRVPVEADDGTWDEFIATGAGALDAVAARAAAVAPQDVSDILFTSGT 180 Query 181 TGRSKGVLCAHRQSLSASASWAANGKITSDDRYLCINPFFHNFGYKAGILACLQTGATLI 240 TGRSKGVLCAHRQSLSASASWAANGKITSDDRYLCINPFFHNFGYKAGILACLQTGATLI Sbjct 181 TGRSKGVLCAHRQSLSASASWAANGKITSDDRYLCINPFFHNFGYKAGILACLQTGATLI 240 Query 241 PHVTFDPLHALRAIERHRITVLPGPPTIYQSLLDHPARKDFDLSSLRFAVTGAATVPVVL 300 PHVTFDPLHALRAIERHRITVLPGPPTIYQSLLDHPARKDFDLSSLRFAVTGAATVPVVL Sbjct 241 PHVTFDPLHALRAIERHRITVLPGPPTIYQSLLDHPARKDFDLSSLRFAVTGAATVPVVL 300 Query 301 VERMQSELDIDIVLTAYGLTEANGMGTMCRPEDDAVTVATTCGRPFADFELRIADDGEVL 360 VERMQSELDIDIVLTAYGLTEANGMGTMCRPEDDAVTVATTCGRPFADFELRIADDGEVL Sbjct 301 VERMQSELDIDIVLTAYGLTEANGMGTMCRPEDDAVTVATTCGRPFADFELRIADDGEVL 360 Query 361 LRGPNVMVGYLDDTEATAAAIDADGWLHTGDIGAVDQAGNLRITDRLKDMYICGGFNVYP 420 LRGPNVMVGYLDDTEATAAAIDADGWLHTGDIGAVDQAGNLRI DRLKDMYICGGFNVYP Sbjct 361 LRGPNVMVGYLDDTEATAAAIDADGWLHTGDIGAVDQAGNLRINDRLKDMYICGGFNVYP 420 Query 421 AEVEQVLARMDGVADAAVIGVPDQRLGEVGRAFVVARPGTGLDEASVIAYTREHLANFKT 480 AEVEQVLARMDGVADAAVIGVPDQRLGEVGRAFVVARPGTGLDEASVIAYTREHLANFKT Sbjct 421 AEVEQVLARMDGVADAAVIGVPDQRLGEVGRAFVVARPGTGLDEASVIAYTREHLANFKT 480 Query 481 PRSVRFVDVLPRNAAGKVSKPQLRELG 507 PRSVRFVDVLPRNAAGKVSKPQLRELG Sbjct 481 PRSVRFVDVLPRNAAGKVSKPQLRELG 507 >gi|15843173|ref|NP_338210.1| long-chain-fatty-acid--CoA ligase [Mycobacterium tuberculosis CDC1551] gi|13883525|gb|AAK48024.1| substrate--CoA ligase [Mycobacterium tuberculosis CDC1551] Length=500 Score = 1002 bits (2590), Expect = 0.0, Method: Compositional matrix adjust. Identities = 499/500 (99%), Positives = 500/500 (100%), Gaps = 0/500 (0%) Query 8 VPAALDRLVRQLPDHTALIAEDRRFTSTELRDAVYGAAAALIALGVEPADRVAIWSPNTW 67 +PAALDRLVRQLPDHTALIAEDRRFTSTELRDAVYGAAAALIALGVEPADRVAIWSPNTW Sbjct 1 MPAALDRLVRQLPDHTALIAEDRRFTSTELRDAVYGAAAALIALGVEPADRVAIWSPNTW 60 Query 68 HWVVACLAIHHAGAAVVPLNTRYTATEATDILDRAGAPVLFAAGLFLGADRAAGLDRAAL 127 HWVVACLAIHHAGAAVVPLNTRYTATEATDILDRAGAPVLFAAGLFLGADRAAGLDRAAL Sbjct 61 HWVVACLAIHHAGAAVVPLNTRYTATEATDILDRAGAPVLFAAGLFLGADRAAGLDRAAL 120 Query 128 PALRHVVRVPVEADDGTWDEFIATGAGALDAVAARAAAVAPQDVSDILFTSGTTGRSKGV 187 PALRHVVRVPVEADDGTWDEFIATGAGALDAVAARAAAVAPQDVSDILFTSGTTGRSKGV Sbjct 121 PALRHVVRVPVEADDGTWDEFIATGAGALDAVAARAAAVAPQDVSDILFTSGTTGRSKGV 180 Query 188 LCAHRQSLSASASWAANGKITSDDRYLCINPFFHNFGYKAGILACLQTGATLIPHVTFDP 247 LCAHRQSLSASASWAANGKITSDDRYLCINPFFHNFGYKAGILACLQTGATLIPHVTFDP Sbjct 181 LCAHRQSLSASASWAANGKITSDDRYLCINPFFHNFGYKAGILACLQTGATLIPHVTFDP 240 Query 248 LHALRAIERHRITVLPGPPTIYQSLLDHPARKDFDLSSLRFAVTGAATVPVVLVERMQSE 307 LHALRAIERHRITVLPGPPTIYQSLLDHPARKDFDLSSLRFAVTGAATVPVVLVERMQSE Sbjct 241 LHALRAIERHRITVLPGPPTIYQSLLDHPARKDFDLSSLRFAVTGAATVPVVLVERMQSE 300 Query 308 LDIDIVLTAYGLTEANGMGTMCRPEDDAVTVATTCGRPFADFELRIADDGEVLLRGPNVM 367 LDIDIVLTAYGLTEANGMGTMCRPEDDAVTVATTCGRPFADFELRIADDGEVLLRGPNVM Sbjct 301 LDIDIVLTAYGLTEANGMGTMCRPEDDAVTVATTCGRPFADFELRIADDGEVLLRGPNVM 360 Query 368 VGYLDDTEATAAAIDADGWLHTGDIGAVDQAGNLRITDRLKDMYICGGFNVYPAEVEQVL 427 VGYLDDTEATAAAIDADGWLHTGDIGAVDQAGNLRITDRLKDMYICGGFNVYPAEVEQVL Sbjct 361 VGYLDDTEATAAAIDADGWLHTGDIGAVDQAGNLRITDRLKDMYICGGFNVYPAEVEQVL 420 Query 428 ARMDGVADAAVIGVPDQRLGEVGRAFVVARPGTGLDEASVIAYTREHLANFKTPRSVRFV 487 ARMDGVADAAVIGVPDQRLGEVGRAFVVARPGTGLDEASVIAYTREHLANFKTPRSVRFV Sbjct 421 ARMDGVADAAVIGVPDQRLGEVGRAFVVARPGTGLDEASVIAYTREHLANFKTPRSVRFV 480 Query 488 DVLPRNAAGKVSKPQLRELG 507 DVLPRNAAGKVSKPQLRELG Sbjct 481 DVLPRNAAGKVSKPQLRELG 500 >gi|340628525|ref|YP_004746977.1| putative fatty-acid-CoA ligase FADD3 [Mycobacterium canettii CIPT 140010059] gi|340006715|emb|CCC45903.1| putative fatty-acid-CoA ligase FADD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) [Mycobacterium canettii CIPT 140010059] Length=507 Score = 954 bits (2467), Expect = 0.0, Method: Compositional matrix adjust. Identities = 488/507 (97%), Positives = 492/507 (98%), Gaps = 0/507 (0%) Query 1 LINDLRTVPAALDRLVRQLPDHTALIAEDRRFTSTELRDAVYGAAAALIALGVEPADRVA 60 +INDLRTVPAALDRLVRQLPDHTALIAEDRRFTSTELRDAVY AAAALIALGVEP DRVA Sbjct 1 MINDLRTVPAALDRLVRQLPDHTALIAEDRRFTSTELRDAVYRAAAALIALGVEPGDRVA 60 Query 61 IWSPNTWHWVVACLAIHHAGAAVVPLNTRYTATEATDILDRAGAPVLFAAGLFLGADRAA 120 IWSPNTWHWVVACLAI HAGAAVVPLNTRYTATEATDIL RAGAPVLFAAGLFLG DRAA Sbjct 61 IWSPNTWHWVVACLAIQHAGAAVVPLNTRYTATEATDILARAGAPVLFAAGLFLGVDRAA 120 Query 121 GLDRAALPALRHVVRVPVEADDGTWDEFIATGAGALDAVAARAAAVAPQDVSDILFTSGT 180 GL RAALPALRHVVRVPVEADDG+W EFIATGAGALDAV ARAAAV P DVSDILFTSGT Sbjct 121 GLHRAALPALRHVVRVPVEADDGSWGEFIATGAGALDAVPARAAAVTPHDVSDILFTSGT 180 Query 181 TGRSKGVLCAHRQSLSASASWAANGKITSDDRYLCINPFFHNFGYKAGILACLQTGATLI 240 TGRSKGVLCAHRQSLSASASWAA GKITSDDRYLCINPFFHNFGYKAGILACLQTGATLI Sbjct 181 TGRSKGVLCAHRQSLSASASWAAIGKITSDDRYLCINPFFHNFGYKAGILACLQTGATLI 240 Query 241 PHVTFDPLHALRAIERHRITVLPGPPTIYQSLLDHPARKDFDLSSLRFAVTGAATVPVVL 300 PHVTFDPL AL+AIERHRITVLPGPPTIYQSLLDHPAR D+DLSSLRFAVTGAATVPVVL Sbjct 241 PHVTFDPLRALQAIERHRITVLPGPPTIYQSLLDHPARNDYDLSSLRFAVTGAATVPVVL 300 Query 301 VERMQSELDIDIVLTAYGLTEANGMGTMCRPEDDAVTVATTCGRPFADFELRIADDGEVL 360 VERMQSELDIDIVLTAYGLTEANGMGTMCRPEDDAVTVATTCGRPFADFELRIADDGEVL Sbjct 301 VERMQSELDIDIVLTAYGLTEANGMGTMCRPEDDAVTVATTCGRPFADFELRIADDGEVL 360 Query 361 LRGPNVMVGYLDDTEATAAAIDADGWLHTGDIGAVDQAGNLRITDRLKDMYICGGFNVYP 420 LRGPNVMVGYLDD EATAAAIDADGWLHTGDIGAVDQAGNLRITDRLKDMYICGGFNVYP Sbjct 361 LRGPNVMVGYLDDPEATAAAIDADGWLHTGDIGAVDQAGNLRITDRLKDMYICGGFNVYP 420 Query 421 AEVEQVLARMDGVADAAVIGVPDQRLGEVGRAFVVARPGTGLDEASVIAYTREHLANFKT 480 AEVEQVLARMDGVADAAVIGVPDQRLGEVGRAFVV RPGTGLDEASVIAYTREHLANFKT Sbjct 421 AEVEQVLARMDGVADAAVIGVPDQRLGEVGRAFVVVRPGTGLDEASVIAYTREHLANFKT 480 Query 481 PRSVRFVDVLPRNAAGKVSKPQLRELG 507 PRSVRFVDVLPRNAAGKVSKPQLRELG Sbjct 481 PRSVRFVDVLPRNAAGKVSKPQLRELG 507 >gi|342862390|ref|ZP_08719030.1| long-chain-fatty-acid--CoA ligase [Mycobacterium colombiense CECT 3035] gi|342130061|gb|EGT83395.1| long-chain-fatty-acid--CoA ligase [Mycobacterium colombiense CECT 3035] Length=514 Score = 853 bits (2203), Expect = 0.0, Method: Compositional matrix adjust. Identities = 429/513 (84%), Positives = 455/513 (89%), Gaps = 9/513 (1%) Query 1 LINDLRTVPAALDRLVRQLPDHTALIAEDRRFTSTELRDAVYGAAAALIALGVEPADRVA 60 + ND RTVPAALDR +LPDH ALI ++R FT+ LRD V AAAALI LGV DRVA Sbjct 1 MTNDPRTVPAALDRFASRLPDHDALITDERSFTAAALRDEVRRAAAALIDLGVRAGDRVA 60 Query 61 IWSPNTWHWVVACLAIHHAGAAVVPLNTRYTATEATDILDRAGAPVLFAAGLFLGADRAA 120 IWSPNTWHWVVACLAIHHAGAA+VPLNTRYTA EA DIL R GAPVLF G FLG DR A Sbjct 61 IWSPNTWHWVVACLAIHHAGAAMVPLNTRYTAAEAGDILARTGAPVLFGMGRFLGNDRVA 120 Query 121 GLDRAALPALRHVVRVPVEADD---GTWDEFIATGAGALDAVAARAAAVAPQDVSDILFT 177 LDRAALPALRH+VR+P+E + G+WDEFIA G+ LDAVAARA+AV P DVSDILFT Sbjct 121 DLDRAALPALRHIVRIPIEDAETGPGSWDEFIARGSD-LDAVAARASAVTPDDVSDILFT 179 Query 178 SGTTGRSKGVLCAHRQSLSASASWAANGKITSDDRYLCINPFFHNFGYKAGILACLQTGA 237 SGTTGRSKGVLCAHRQSLSASA+WA NGKITSDDRYLCINPFFHNFGYKAGILACLQTGA Sbjct 180 SGTTGRSKGVLCAHRQSLSASAAWATNGKITSDDRYLCINPFFHNFGYKAGILACLQTGA 239 Query 238 TLIPHVTFDPLHALRAIERHRITVLPGPPTIYQSLLDHPARKDFDLSSLRFAVTGAATVP 297 TLIPH+TFDPL AL+AIER+RITVLPGPPTIYQ+LLDHPAR D+DLSSLRFAVTGAATVP Sbjct 240 TLIPHLTFDPLRALQAIERNRITVLPGPPTIYQTLLDHPARGDYDLSSLRFAVTGAATVP 299 Query 298 VVLVERMQSELDIDIVLTAYGLTEANGMGTMCRPEDDAVTVATTCGRPFADFELRI---- 353 VVLVERMQSELDIDIVLTAYGLTEANGMGTMCR +DDAVTVATTCGRPFADFELRI Sbjct 300 VVLVERMQSELDIDIVLTAYGLTEANGMGTMCRADDDAVTVATTCGRPFADFELRIDADS 359 Query 354 -ADDGEVLLRGPNVMVGYLDDTEATAAAIDADGWLHTGDIGAVDQAGNLRITDRLKDMYI 412 + GEVLLRGPNVM+GYL+D EATAAAIDADGWLHTGDIGAVD AGNLRITDRLKDMYI Sbjct 360 PGESGEVLLRGPNVMLGYLEDPEATAAAIDADGWLHTGDIGAVDAAGNLRITDRLKDMYI 419 Query 413 CGGFNVYPAEVEQVLARMDGVADAAVIGVPDQRLGEVGRAFVVARPGTGLDEASVIAYTR 472 CGGFNVYPAEVEQVLARMDGVADAAVIGVPD+RLGEVGRA++V RPG LDE SVIAYTR Sbjct 420 CGGFNVYPAEVEQVLARMDGVADAAVIGVPDERLGEVGRAYLVTRPGAQLDEQSVIAYTR 479 Query 473 EHLANFKTPRSVRFVDVLPRNAAGKVSKPQLRE 505 EHLANFK PRSVRFVD LPRNA GKV KPQLRE Sbjct 480 EHLANFKAPRSVRFVDALPRNAGGKVVKPQLRE 512 >gi|118619306|ref|YP_907638.1| acyl-CoA synthetase [Mycobacterium ulcerans Agy99] gi|118571416|gb|ABL06167.1| fatty-acid-CoA ligase FadD3 [Mycobacterium ulcerans Agy99] Length=507 Score = 838 bits (2165), Expect = 0.0, Method: Compositional matrix adjust. Identities = 424/507 (84%), Positives = 453/507 (90%), Gaps = 2/507 (0%) Query 1 LINDLRTVPAALDRLVRQLPDHTALIAEDRRFTSTELRDAVYGAAAALIALGVEPADRVA 60 + +D RTVP ALDRLVR+LP+H AL+ ++R FT +EL D VY AAAALI LGV+PA RV Sbjct 1 MTSDPRTVPTALDRLVRRLPNHDALVTDERSFTVSELNDEVYRAAAALIELGVKPAARVG 60 Query 61 IWSPNTWHWVVACLAIHHAGAAVVPLNTRYTATEATDILDRAGAPVLFAAGLFLGADRAA 120 IWSPNTWHWVVACLAIHH GAA+VPLNTRYTA EA DIL R APVLFA G FLG+DR A Sbjct 61 IWSPNTWHWVVACLAIHHVGAAMVPLNTRYTADEAADILARTEAPVLFAMGHFLGSDRVA 120 Query 121 GLDRAALPALRHVVRVPVEADDGTWDEFIATGAGALDAVAARAAAVAPQDVSDILFTSGT 180 GLDR ALPALRH+VR+P+E DGTWDEFI TG AV ARAAAV+P DVSDILFTSGT Sbjct 121 GLDRKALPALRHIVRIPIEEPDGTWDEFIETGTDT-GAVTARAAAVSPDDVSDILFTSGT 179 Query 181 TGRSKGVLCAHRQSLSASASWAANGKITSDDRYLCINPFFHNFGYKAGILACLQTGATLI 240 TGRSKGVLCAHRQSLSASASWAANGKIT+DDR+LCINPFFHNFGYKAGILACLQTGATL Sbjct 180 TGRSKGVLCAHRQSLSASASWAANGKITADDRHLCINPFFHNFGYKAGILACLQTGATLF 239 Query 241 PHVTFDPLHALRAIERHRITVLPGPPTIYQSLLDHPARKDFDLSSLRFAVTGAATVPVVL 300 PH+TFDPL L+AIERHRITVLPGPPTIYQ+LLDHPAR D+DLSSLRFAVTGAATVPVVL Sbjct 240 PHLTFDPLRTLQAIERHRITVLPGPPTIYQTLLDHPARDDYDLSSLRFAVTGAATVPVVL 299 Query 301 VERMQSELDIDIVLTAYGLTEANGMGTMCRPEDDAVTVATTCGRPFADFELRIA-DDGEV 359 VERMQSELDIDIVLTAYGLTEANGMGTMCR +DDA+TVATTCGRPFADFELRI D GEV Sbjct 300 VERMQSELDIDIVLTAYGLTEANGMGTMCRADDDALTVATTCGRPFADFELRIGPDTGEV 359 Query 360 LLRGPNVMVGYLDDTEATAAAIDADGWLHTGDIGAVDQAGNLRITDRLKDMYICGGFNVY 419 LLRGPNVM+GYLDD ATAAAIDADGWLHTGDIG +D+AGNLRITDRLKDMYICGGFNVY Sbjct 360 LLRGPNVMLGYLDDPRATAAAIDADGWLHTGDIGVLDEAGNLRITDRLKDMYICGGFNVY 419 Query 420 PAEVEQVLARMDGVADAAVIGVPDQRLGEVGRAFVVARPGTGLDEASVIAYTREHLANFK 479 PAEVEQVLAR+DGVAD AVIG+PD RLGEVGRAF+VARPG LDE SVI YTREHLANFK Sbjct 420 PAEVEQVLARLDGVADVAVIGIPDHRLGEVGRAFIVARPGFNLDEKSVIDYTREHLANFK 479 Query 480 TPRSVRFVDVLPRNAAGKVSKPQLREL 506 PRSVRFVD LPRNA GKV KPQLREL Sbjct 480 APRSVRFVDTLPRNAGGKVVKPQLREL 506 >gi|240169776|ref|ZP_04748435.1| acyl-CoA synthetase [Mycobacterium kansasii ATCC 12478] Length=516 Score = 835 bits (2157), Expect = 0.0, Method: Compositional matrix adjust. Identities = 429/516 (84%), Positives = 456/516 (89%), Gaps = 11/516 (2%) Query 1 LINDLRTVPAALDRLVRQLPDHTALIAEDRRFTSTELRDAVYGAAAALIALGVEPADRVA 60 + +D RTVPAALDRL PDH LI +DR FT+T LR V+ AA+ALIALGVEP DRVA Sbjct 1 MTDDPRTVPAALDRLAGMFPDHDVLITDDRSFTATTLRAEVHRAASALIALGVEPGDRVA 60 Query 61 IWSPNTWHWVVACLAIHHAGAAVVPLNTRYTATEATDILDRAGAPVLFAAGLFLGADRAA 120 IWSPNTWHWVVACLAIHHAGAA+VPLNTRYTA EA DIL R APVLFA G FLGADR A Sbjct 61 IWSPNTWHWVVACLAIHHAGAAMVPLNTRYTAEEAGDILSRTRAPVLFAMGRFLGADRVA 120 Query 121 GLD--RAALPALRHVVRVPVEADD---GTWDEFIATGAGALDAVAARAAAVAPQDVSDIL 175 GLD ALPALRH+VR+P+EADD GTWDEFIA G AV RAAAV P DVSDIL Sbjct 121 GLDLNSQALPALRHIVRIPIEADDPVRGTWDEFIAQGTDT-QAVELRAAAVTPNDVSDIL 179 Query 176 FTSGTTGRSKGVLCAHRQSLSASASWAANGKITSDDRYLCINPFFHNFGYKAGILACLQT 235 FTSGTTGRSKGVLCAHRQSL+ASASWAANGKIT DDRYLCINPFFHNFGYKAGILACLQT Sbjct 180 FTSGTTGRSKGVLCAHRQSLAASASWAANGKITGDDRYLCINPFFHNFGYKAGILACLQT 239 Query 236 GATLIPHVTFDPLHALRAIERHRITVLPGPPTIYQSLLDHPARKDFDLSSLRFAVTGAAT 295 GATLIPH+TFDPL L+AIE+HRITVLPGPPTIYQ+LLDHPAR+++DL+SLRFAVTGAAT Sbjct 240 GATLIPHLTFDPLRTLQAIEQHRITVLPGPPTIYQTLLDHPARRNYDLTSLRFAVTGAAT 299 Query 296 VPVVLVERMQSELDIDIVLTAYGLTEANGMGTMCRPEDDAVTVATTCGRPFADFELRI-- 353 VPVVLVERMQSELDIDIVLTAYGLTEANGMGTMCRP+DDAVTVATTCGRPFA FELRI Sbjct 300 VPVVLVERMQSELDIDIVLTAYGLTEANGMGTMCRPDDDAVTVATTCGRPFAGFELRIDA 359 Query 354 ---ADDGEVLLRGPNVMVGYLDDTEATAAAIDADGWLHTGDIGAVDQAGNLRITDRLKDM 410 ++ GEVLLRGPNVM+GYLDD EATA AID+DGWLHTGDIGAVD+AGNLRITDRLKDM Sbjct 360 ETGSETGEVLLRGPNVMLGYLDDPEATATAIDSDGWLHTGDIGAVDEAGNLRITDRLKDM 419 Query 411 YICGGFNVYPAEVEQVLARMDGVADAAVIGVPDQRLGEVGRAFVVARPGTGLDEASVIAY 470 YICGGFNVYPAEVEQVLAR+DGVADAAVIGVPDQRLGEVGRAFVV RPG LDEA+VIAY Sbjct 420 YICGGFNVYPAEVEQVLARLDGVADAAVIGVPDQRLGEVGRAFVVPRPGANLDEATVIAY 479 Query 471 TREHLANFKTPRSVRFVDVLPRNAAGKVSKPQLREL 506 TREHLANFK PRSVRFVD LPRNA GKV K QLREL Sbjct 480 TREHLANFKAPRSVRFVDALPRNAGGKVVKSQLREL 515 >gi|336458500|gb|EGO37473.1| acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II [Mycobacterium avium subsp. paratuberculosis S397] Length=509 Score = 827 bits (2135), Expect = 0.0, Method: Compositional matrix adjust. Identities = 436/509 (86%), Positives = 459/509 (91%), Gaps = 4/509 (0%) Query 1 LINDLRTVPAALDRLVRQLPDHTALIAEDRRFTSTELRDAVYGAAAALIALGVEPADRVA 60 + D RTVPAALDRL R+LPDH ALI EDR FT+ LRD V+ AAAALI LGV DRVA Sbjct 1 MTTDPRTVPAALDRLARRLPDHDALITEDRSFTAAALRDEVHRAAAALIELGVRAGDRVA 60 Query 61 IWSPNTWHWVVACLAIHHAGAAVVPLNTRYTATEATDILDRAGAPVLFAAGLFLGADRAA 120 IWSPNTWHWVVACLAIHHAGAA+VPLNTRYTA EA DIL R GAPVLF G FLG DR A Sbjct 61 IWSPNTWHWVVACLAIHHAGAAMVPLNTRYTAAEAGDILARVGAPVLFGMGRFLGHDRLA 120 Query 121 GLDRAALPALRHVVRVPVEADD---GTWDEFIATGAGALDAVAARAAAVAPQDVSDILFT 177 LDRAALPALRH+VR+P+EADD G+WDEFIA G L AVA RAAAV P DVSDILFT Sbjct 121 DLDRAALPALRHIVRIPIEADDPVPGSWDEFIAHGTD-LGAVAERAAAVTPDDVSDILFT 179 Query 178 SGTTGRSKGVLCAHRQSLSASASWAANGKITSDDRYLCINPFFHNFGYKAGILACLQTGA 237 SGTTGRSKGVLCAHRQSLSASASWAANGKITSDDRYLCINPFFHNFGYKAGILACLQTGA Sbjct 180 SGTTGRSKGVLCAHRQSLSASASWAANGKITSDDRYLCINPFFHNFGYKAGILACLQTGA 239 Query 238 TLIPHVTFDPLHALRAIERHRITVLPGPPTIYQSLLDHPARKDFDLSSLRFAVTGAATVP 297 TLIPH+TFDPL AL+AIE+HRITVLPGPPTIYQ+LLDHPAR+D+DLSSLRFAVTGAATVP Sbjct 240 TLIPHLTFDPLRALQAIEQHRITVLPGPPTIYQTLLDHPARRDYDLSSLRFAVTGAATVP 299 Query 298 VVLVERMQSELDIDIVLTAYGLTEANGMGTMCRPEDDAVTVATTCGRPFADFELRIADDG 357 VVLVERMQSELDIDIVLTAYGLTEANGMGTMCR +DDAVTVATTCGRPFADFELRI D G Sbjct 300 VVLVERMQSELDIDIVLTAYGLTEANGMGTMCRADDDAVTVATTCGRPFADFELRIDDSG 359 Query 358 EVLLRGPNVMVGYLDDTEATAAAIDADGWLHTGDIGAVDQAGNLRITDRLKDMYICGGFN 417 EVLLRGPNVM+GYLDD +ATAAAIDADGWLHTGDIG +D+AGNLRITDRLKDMYICGGFN Sbjct 360 EVLLRGPNVMLGYLDDPDATAAAIDADGWLHTGDIGVLDEAGNLRITDRLKDMYICGGFN 419 Query 418 VYPAEVEQVLARMDGVADAAVIGVPDQRLGEVGRAFVVARPGTGLDEASVIAYTREHLAN 477 VYPAEVEQVLARM+GVADAAVIGVPD+RLGEVGRAFVV RPG LDE SVIAYTREHLAN Sbjct 420 VYPAEVEQVLARMEGVADAAVIGVPDERLGEVGRAFVVPRPGAQLDEQSVIAYTREHLAN 479 Query 478 FKTPRSVRFVDVLPRNAAGKVSKPQLREL 506 FK PRSVRFVD LPRN+ GKV KPQLREL Sbjct 480 FKAPRSVRFVDALPRNSGGKVVKPQLREL 508 >gi|183985018|ref|YP_001853309.1| fatty-acid-CoA ligase FadD3 [Mycobacterium marinum M] gi|183178344|gb|ACC43454.1| fatty-acid-CoA ligase FadD3 [Mycobacterium marinum M] Length=507 Score = 825 bits (2130), Expect = 0.0, Method: Compositional matrix adjust. Identities = 426/507 (85%), Positives = 454/507 (90%), Gaps = 2/507 (0%) Query 1 LINDLRTVPAALDRLVRQLPDHTALIAEDRRFTSTELRDAVYGAAAALIALGVEPADRVA 60 + +D RTVP ALDRLVR+LP+H AL+ ++R FT +EL D VY AAAALI LGV+PA RV Sbjct 1 MTSDPRTVPTALDRLVRRLPNHDALVTDERSFTVSELHDEVYRAAAALIELGVKPAARVG 60 Query 61 IWSPNTWHWVVACLAIHHAGAAVVPLNTRYTATEATDILDRAGAPVLFAAGLFLGADRAA 120 IWSPNTWHWVVACLAIHH GAA+VPLNTRYTA EA DIL R APVLFA G FLG+DR A Sbjct 61 IWSPNTWHWVVACLAIHHVGAAMVPLNTRYTADEAADILARTEAPVLFAMGHFLGSDRVA 120 Query 121 GLDRAALPALRHVVRVPVEADDGTWDEFIATGAGALDAVAARAAAVAPQDVSDILFTSGT 180 GLDR ALPALRH+VR+P+E DGTWDEFI TG AVAARAAAV+P DVSDILFTSGT Sbjct 121 GLDRKALPALRHIVRIPIEEPDGTWDEFIETGTDT-GAVAARAAAVSPDDVSDILFTSGT 179 Query 181 TGRSKGVLCAHRQSLSASASWAANGKITSDDRYLCINPFFHNFGYKAGILACLQTGATLI 240 TGRSKGVLCAHRQSLSASASWAANGKIT+DDRYLCINPFFHNFGYKAGILACLQTGATL Sbjct 180 TGRSKGVLCAHRQSLSASASWAANGKITADDRYLCINPFFHNFGYKAGILACLQTGATLF 239 Query 241 PHVTFDPLHALRAIERHRITVLPGPPTIYQSLLDHPARKDFDLSSLRFAVTGAATVPVVL 300 PH+TFDPL L+AIERHRITVLPGPPTIYQ+LLDHPAR D+DLSSLRFAVTGAATVPVVL Sbjct 240 PHLTFDPLRTLQAIERHRITVLPGPPTIYQTLLDHPARDDYDLSSLRFAVTGAATVPVVL 299 Query 301 VERMQSELDIDIVLTAYGLTEANGMGTMCRPEDDAVTVATTCGRPFADFELRIA-DDGEV 359 VERMQSELDIDIVLTAYGLTEANGMGTMCR +DDA+TVATTCGRPFADFELRI D GEV Sbjct 300 VERMQSELDIDIVLTAYGLTEANGMGTMCRADDDALTVATTCGRPFADFELRIGPDTGEV 359 Query 360 LLRGPNVMVGYLDDTEATAAAIDADGWLHTGDIGAVDQAGNLRITDRLKDMYICGGFNVY 419 LLRGPNVM+GYLDD ATAAAIDADGWLHTGDIG +D+AGNLRITDRLKDMYICGGFNVY Sbjct 360 LLRGPNVMLGYLDDPRATAAAIDADGWLHTGDIGVLDEAGNLRITDRLKDMYICGGFNVY 419 Query 420 PAEVEQVLARMDGVADAAVIGVPDQRLGEVGRAFVVARPGTGLDEASVIAYTREHLANFK 479 PAEVEQVLAR+DGVAD AVIG+PD RLGEVGRAF+VARPG LDE SVI YTREHLANFK Sbjct 420 PAEVEQVLARLDGVADVAVIGIPDHRLGEVGRAFIVARPGFNLDEKSVIDYTREHLANFK 479 Query 480 TPRSVRFVDVLPRNAAGKVSKPQLREL 506 PRSVRFVD LPRNA GKV KPQLREL Sbjct 480 APRSVRFVDTLPRNAGGKVVKPQLREL 506 >gi|118466679|ref|YP_879880.1| long-chain-fatty-acid--CoA ligase [Mycobacterium avium 104] gi|118167966|gb|ABK68863.1| probable fatty-acid-coa ligase fadd3 (fatty-acid-coa synthetase) [Mycobacterium avium 104] Length=509 Score = 821 bits (2121), Expect = 0.0, Method: Compositional matrix adjust. Identities = 433/509 (86%), Positives = 457/509 (90%), Gaps = 4/509 (0%) Query 1 LINDLRTVPAALDRLVRQLPDHTALIAEDRRFTSTELRDAVYGAAAALIALGVEPADRVA 60 + D RTVPAALDRL R+LPDH ALI EDR FT+ LRD V+ AAAALI LGV DRVA Sbjct 1 MTTDPRTVPAALDRLARRLPDHDALITEDRSFTAAALRDEVHRAAAALIELGVRAGDRVA 60 Query 61 IWSPNTWHWVVACLAIHHAGAAVVPLNTRYTATEATDILDRAGAPVLFAAGLFLGADRAA 120 IWSPNTWHWVVACLAIHHAGAA+VPLNTRYTA EA DIL R GAPVLF G FLG DR A Sbjct 61 IWSPNTWHWVVACLAIHHAGAAMVPLNTRYTAAEAGDILARVGAPVLFGMGRFLGHDRLA 120 Query 121 GLDRAALPALRHVVRVPVEADD---GTWDEFIATGAGALDAVAARAAAVAPQDVSDILFT 177 LDRAALPALRH+VR+P+E DD G+WDEFIA G L AVA RAAAV DVSDILFT Sbjct 121 DLDRAALPALRHIVRIPIETDDPVPGSWDEFIAHGTD-LGAVAERAAAVTSDDVSDILFT 179 Query 178 SGTTGRSKGVLCAHRQSLSASASWAANGKITSDDRYLCINPFFHNFGYKAGILACLQTGA 237 SGTTGRSKGVLCAHRQSLSASASWAANGKITSDDRYLCINPFFHNFGYKAGILACLQTGA Sbjct 180 SGTTGRSKGVLCAHRQSLSASASWAANGKITSDDRYLCINPFFHNFGYKAGILACLQTGA 239 Query 238 TLIPHVTFDPLHALRAIERHRITVLPGPPTIYQSLLDHPARKDFDLSSLRFAVTGAATVP 297 TLIPH+TFDPL AL+AIE+HRITVLPGPPTIYQ+LLDHPAR+D+DLSSLRFAVTGAATVP Sbjct 240 TLIPHLTFDPLRALQAIEQHRITVLPGPPTIYQTLLDHPARRDYDLSSLRFAVTGAATVP 299 Query 298 VVLVERMQSELDIDIVLTAYGLTEANGMGTMCRPEDDAVTVATTCGRPFADFELRIADDG 357 VVLVERMQSELDIDIVLTAYGLTEANGMGTMCR +DDAVTVATTCGRPFADFELRI D G Sbjct 300 VVLVERMQSELDIDIVLTAYGLTEANGMGTMCRADDDAVTVATTCGRPFADFELRIDDSG 359 Query 358 EVLLRGPNVMVGYLDDTEATAAAIDADGWLHTGDIGAVDQAGNLRITDRLKDMYICGGFN 417 EVLLRGPNVM+GYLDD +ATAAAIDADGWLHTGDIG +D+AGNLRITDRLKDMYICGGFN Sbjct 360 EVLLRGPNVMLGYLDDPDATAAAIDADGWLHTGDIGVLDEAGNLRITDRLKDMYICGGFN 419 Query 418 VYPAEVEQVLARMDGVADAAVIGVPDQRLGEVGRAFVVARPGTGLDEASVIAYTREHLAN 477 VYPAEVEQVLARM+GVADAAVIGVPD+RLGEVGRAFVV RPG LDE SVIAYTR+HLAN Sbjct 420 VYPAEVEQVLARMEGVADAAVIGVPDERLGEVGRAFVVPRPGAQLDEQSVIAYTRDHLAN 479 Query 478 FKTPRSVRFVDVLPRNAAGKVSKPQLREL 506 FK PRSVRFVD LPRN+ GKV KPQLREL Sbjct 480 FKAPRSVRFVDALPRNSGGKVVKPQLREL 508 >gi|254773557|ref|ZP_05215073.1| long-chain-fatty-acid--CoA ligase [Mycobacterium avium subsp. avium ATCC 25291] Length=509 Score = 820 bits (2117), Expect = 0.0, Method: Compositional matrix adjust. Identities = 432/509 (85%), Positives = 456/509 (90%), Gaps = 4/509 (0%) Query 1 LINDLRTVPAALDRLVRQLPDHTALIAEDRRFTSTELRDAVYGAAAALIALGVEPADRVA 60 + D RTVPAALDRL R+LPDH ALI EDR FT+ LRD V+ AAAALI LGV DRVA Sbjct 1 MTTDPRTVPAALDRLARRLPDHDALITEDRSFTAAALRDEVHRAAAALIELGVRAGDRVA 60 Query 61 IWSPNTWHWVVACLAIHHAGAAVVPLNTRYTATEATDILDRAGAPVLFAAGLFLGADRAA 120 IWSPNTWHWVVACLAIHHAGAA+VPLNTRYTA EA DIL R GAPVLF G FLG DR A Sbjct 61 IWSPNTWHWVVACLAIHHAGAAMVPLNTRYTAAEAGDILARVGAPVLFGMGRFLGHDRLA 120 Query 121 GLDRAALPALRHVVRVPVEADD---GTWDEFIATGAGALDAVAARAAAVAPQDVSDILFT 177 LDRAALPALRH+VR+P+E DD G+WDEFIA G L AVA R AAV DVSDILFT Sbjct 121 DLDRAALPALRHIVRIPIETDDPVPGSWDEFIAHGTD-LGAVAERTAAVTSDDVSDILFT 179 Query 178 SGTTGRSKGVLCAHRQSLSASASWAANGKITSDDRYLCINPFFHNFGYKAGILACLQTGA 237 SGTTGRSKGVLCAHRQSLSASASWAANGKITSDDRYLCINPFFHNFGYKAGILACLQTGA Sbjct 180 SGTTGRSKGVLCAHRQSLSASASWAANGKITSDDRYLCINPFFHNFGYKAGILACLQTGA 239 Query 238 TLIPHVTFDPLHALRAIERHRITVLPGPPTIYQSLLDHPARKDFDLSSLRFAVTGAATVP 297 TLIPH+TFDPL AL+AIE+HRITVLPGPPTIYQ+LLDHPAR+D+DLSSLRFAVTGAATVP Sbjct 240 TLIPHLTFDPLRALQAIEQHRITVLPGPPTIYQTLLDHPARRDYDLSSLRFAVTGAATVP 299 Query 298 VVLVERMQSELDIDIVLTAYGLTEANGMGTMCRPEDDAVTVATTCGRPFADFELRIADDG 357 VVLVERMQSELDIDIVLTAYGLTEANGMGTMCR +DDAVTVATTCGRPFADFELRI D G Sbjct 300 VVLVERMQSELDIDIVLTAYGLTEANGMGTMCRADDDAVTVATTCGRPFADFELRIDDSG 359 Query 358 EVLLRGPNVMVGYLDDTEATAAAIDADGWLHTGDIGAVDQAGNLRITDRLKDMYICGGFN 417 EVLLRGPNVM+GYLDD +ATAAAIDADGWLHTGDIG +D+AGNLRITDRLKDMYICGGFN Sbjct 360 EVLLRGPNVMLGYLDDPDATAAAIDADGWLHTGDIGVLDEAGNLRITDRLKDMYICGGFN 419 Query 418 VYPAEVEQVLARMDGVADAAVIGVPDQRLGEVGRAFVVARPGTGLDEASVIAYTREHLAN 477 VYPAEVEQVLARM+GVADAAVIGVPD+RLGEVGRAFVV RPG LDE SVIAYTR+HLAN Sbjct 420 VYPAEVEQVLARMEGVADAAVIGVPDERLGEVGRAFVVPRPGAQLDEQSVIAYTRDHLAN 479 Query 478 FKTPRSVRFVDVLPRNAAGKVSKPQLREL 506 FK PRSVRFVD LPRN+ GKV KPQLREL Sbjct 480 FKAPRSVRFVDALPRNSGGKVVKPQLREL 508 >gi|254822643|ref|ZP_05227644.1| long-chain-fatty-acid--CoA ligase [Mycobacterium intracellulare ATCC 13950] Length=511 Score = 811 bits (2095), Expect = 0.0, Method: Compositional matrix adjust. Identities = 435/511 (86%), Positives = 458/511 (90%), Gaps = 6/511 (1%) Query 1 LINDLRTVPAALDRLVRQLPDHTALIAEDRRFTSTELRDAVYGAAAALIALGVEPADRVA 60 + D RTVPAALDR RQLPDH AL+ EDR FT+ LRD V+ AAAALIALGV+P DRVA Sbjct 1 MTTDPRTVPAALDRFARQLPDHDALVTEDRSFTAAALRDEVHRAAAALIALGVQPGDRVA 60 Query 61 IWSPNTWHWVVACLAIHHAGAAVVPLNTRYTATEATDILDRAGAPVLFAAGLFLGADRAA 120 IWSPNTWHWVVACLAIHHAGAA+VPLNTRYTA EA DIL R APVLF G FLG DR A Sbjct 61 IWSPNTWHWVVACLAIHHAGAAMVPLNTRYTAAEAGDILARVEAPVLFGMGEFLGNDRVA 120 Query 121 GLDRAALPALRHVVRVPVEADDGTWDEFIATGAGALDAVAARAAAVAPQDVSDILFTSGT 180 LDRAALPALRH+VR+P++A DGTWDEFIA G LDAVAARAAAV P DVSDILFTSGT Sbjct 121 DLDRAALPALRHIVRIPIDAADGTWDEFIAGGTD-LDAVAARAAAVTPDDVSDILFTSGT 179 Query 181 TGRSKGVLCAHRQSLSASASWAANGKITSDDRYLCINPFFHNFGYKAGILACLQTGATLI 240 TGRSKGVLCAHRQSLSASASWAANGKIT+DDRYLCINPFFHNFGYKAGILACLQTGATLI Sbjct 180 TGRSKGVLCAHRQSLSASASWAANGKITADDRYLCINPFFHNFGYKAGILACLQTGATLI 239 Query 241 PHVTFDPLHALRAIERHRITVLPGPPTIYQSLLDHPARKDFDLSSLRFAVTGAATVPVVL 300 PH+TFDPL ALRAIE+HRITVLPGPPTIYQ+LLDHPAR D+DLSSLRFAVTGAATVPVVL Sbjct 240 PHLTFDPLRALRAIEQHRITVLPGPPTIYQTLLDHPARGDYDLSSLRFAVTGAATVPVVL 299 Query 301 VERMQSELDIDIVLTAYGLTEANGMGTMCRPEDDAVTVATTCGRPFADFELRI-----AD 355 VERMQSELDIDIVLTAYGLTEANGMGTMCR +DDAVTVATTCGRPFADFELRI + Sbjct 300 VERMQSELDIDIVLTAYGLTEANGMGTMCRADDDAVTVATTCGRPFADFELRIDSGESGE 359 Query 356 DGEVLLRGPNVMVGYLDDTEATAAAIDADGWLHTGDIGAVDQAGNLRITDRLKDMYICGG 415 GEVLLRG NVM+GYLDD ATAAAIDADGWLHTGDIG +D AGNLRITDRLKDMYICGG Sbjct 360 SGEVLLRGHNVMLGYLDDPAATAAAIDADGWLHTGDIGVLDAAGNLRITDRLKDMYICGG 419 Query 416 FNVYPAEVEQVLARMDGVADAAVIGVPDQRLGEVGRAFVVARPGTGLDEASVIAYTREHL 475 FNVYPAE+EQVLAR+DGVADAAVIGVPD+RLGEVGRAF+V RPG LDE SVIAYTREHL Sbjct 420 FNVYPAEIEQVLARLDGVADAAVIGVPDERLGEVGRAFLVTRPGAQLDEQSVIAYTREHL 479 Query 476 ANFKTPRSVRFVDVLPRNAAGKVSKPQLREL 506 ANFKTPRSVRFVD LPRNA GKV KPQLREL Sbjct 480 ANFKTPRSVRFVDALPRNAGGKVLKPQLREL 510 >gi|296166606|ref|ZP_06849035.1| substrate-CoA ligase [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295898036|gb|EFG77613.1| substrate-CoA ligase [Mycobacterium parascrofulaceum ATCC BAA-614] Length=511 Score = 802 bits (2072), Expect = 0.0, Method: Compositional matrix adjust. Identities = 436/510 (86%), Positives = 456/510 (90%), Gaps = 6/510 (1%) Query 1 LINDLRTVPAALDRLVRQLPDHTALIAEDRRFTSTELRDAVYGAAAALIALGVEPADRVA 60 + +D RTVPAALDRL +QLP H ALI +DR FTS LRD V+ AAAALI LGV DRVA Sbjct 1 MTHDPRTVPAALDRLAQQLPGHDALITDDRSFTSATLRDEVHRAAAALIGLGVAAGDRVA 60 Query 61 IWSPNTWHWVVACLAIHHAGAAVVPLNTRYTATEATDILDRAGAPVLFAAGLFLGADRAA 120 +WSPNTWHWVVACLAIHHAGAA+VPLNTRYTA EA DIL R GAPVLF G FLG DR A Sbjct 61 VWSPNTWHWVVACLAIHHAGAAMVPLNTRYTAEEAGDILARTGAPVLFGMGTFLGHDRVA 120 Query 121 GLDRAALPALRHVVRVPVEADDGTWDEFIATGAGALDAVAARAAAVAPQDVSDILFTSGT 180 L R ALPALRH+VR+PV+ADDGTWDEFIA G L+AVAARAAAVAP DVSDILFTSGT Sbjct 121 DLKRDALPALRHIVRIPVDADDGTWDEFIAHGTD-LEAVAARAAAVAPDDVSDILFTSGT 179 Query 181 TGRSKGVLCAHRQSLSASASWAANGKITSDDRYLCINPFFHNFGYKAGILACLQTGATLI 240 TGRSKGVLCAHRQSLSASASWAANGKITSDDRYLCINPFFHNFGYKAGILACLQTGATLI Sbjct 180 TGRSKGVLCAHRQSLSASASWAANGKITSDDRYLCINPFFHNFGYKAGILACLQTGATLI 239 Query 241 PHVTFDPLHALRAIERHRITVLPGPPTIYQSLLDHPARKDFDLSSLRFAVTGAATVPVVL 300 PH+TFDPL AL+AIERHRITVLPGPPTIYQ+LLDHP RKD+DLS+LRFAVTGAATVPVVL Sbjct 240 PHLTFDPLRALQAIERHRITVLPGPPTIYQTLLDHPQRKDYDLSTLRFAVTGAATVPVVL 299 Query 301 VERMQSELDIDIVLTAYGLTEANGMGTMCRPEDDAVTVATTCGRPFADFELRI-ADD--- 356 VERMQSELDIDIVLTAYGLTEANGMGTMCR +DDAVTVATTCGRPFADFELRI A D Sbjct 300 VERMQSELDIDIVLTAYGLTEANGMGTMCRADDDAVTVATTCGRPFADFELRIDASDSGA 359 Query 357 -GEVLLRGPNVMVGYLDDTEATAAAIDADGWLHTGDIGAVDQAGNLRITDRLKDMYICGG 415 GEVLLRGPNVM+GYLDD ATAAAIDADGWLHTGDIGAVD AGNLRITDRLKDMYICGG Sbjct 360 AGEVLLRGPNVMLGYLDDPAATAAAIDADGWLHTGDIGAVDAAGNLRITDRLKDMYICGG 419 Query 416 FNVYPAEVEQVLARMDGVADAAVIGVPDQRLGEVGRAFVVARPGTGLDEASVIAYTREHL 475 FNVYPAEVEQVLARM G+ADAAVIGVPD+RLGEVGRAFVV RPG LDE SVIAYTREHL Sbjct 420 FNVYPAEVEQVLARMPGIADAAVIGVPDERLGEVGRAFVVTRPGADLDEQSVIAYTREHL 479 Query 476 ANFKTPRSVRFVDVLPRNAAGKVSKPQLRE 505 ANFK PRSVRFVD LPRN GKV KPQLRE Sbjct 480 ANFKAPRSVRFVDALPRNPGGKVVKPQLRE 509 >gi|120406234|ref|YP_956063.1| long-chain-fatty-acid--CoA ligase [Mycobacterium vanbaalenii PYR-1] gi|119959052|gb|ABM16057.1| AMP-dependent synthetase and ligase [Mycobacterium vanbaalenii PYR-1] Length=523 Score = 784 bits (2025), Expect = 0.0, Method: Compositional matrix adjust. Identities = 387/519 (75%), Positives = 430/519 (83%), Gaps = 19/519 (3%) Query 5 LRTVPAALDRLVRQLPDHTALI------------------AEDRRFTSTELRDAVYGAAA 46 +RT PA LDR+ R+LPDH A++ A R T ELR V AAA Sbjct 1 MRTTPAVLDRIARELPDHPAVVTTAGGAGNPAVAGESGNPAAARTLTYAELRAEVRQAAA 60 Query 47 ALIALGVEPADRVAIWSPNTWHWVVACLAIHHAGAAVVPLNTRYTATEATDILDRAGAPV 106 ALI LG+EP DRVAIWSPNTWHWVVACLAIHHAG +VPLNTRYTA+EA DIL R AP+ Sbjct 61 ALIDLGIEPGDRVAIWSPNTWHWVVACLAIHHAGGVLVPLNTRYTASEAEDILVRTAAPL 120 Query 107 LFAAGLFLGADRAAGLDRAALPALRHVVRVPVEADDGTWDEFIATGAGALDAVAARAAAV 166 LFA+G FLGAD+AA +DR A+PALRHVVR+P+E DGTWDEF++ GA LDAV R AAV Sbjct 121 LFASGEFLGADKAASVDRDAVPALRHVVRIPIEKSDGTWDEFMSRGAN-LDAVDERVAAV 179 Query 167 APQDVSDILFTSGTTGRSKGVLCAHRQSLSASASWAANGKITSDDRYLCINPFFHNFGYK 226 DVSDILFTSGTTGRSKGV CAHRQSL ASA+WAA G++TSDDRYLCINPFFHNFGYK Sbjct 180 TGDDVSDILFTSGTTGRSKGVRCAHRQSLDASAAWAACGQVTSDDRYLCINPFFHNFGYK 239 Query 227 AGILACLQTGATLIPHVTFDPLHALRAIERHRITVLPGPPTIYQSLLDHPARKDFDLSSL 286 AGILACLQTGATL P +TFDP +A+RA++ H ITVLPGPPTIYQ+LLDHP R D+DLSSL Sbjct 240 AGILACLQTGATLFPELTFDPENAMRAVQEHGITVLPGPPTIYQTLLDHPKRGDYDLSSL 299 Query 287 RFAVTGAATVPVVLVERMQSELDIDIVLTAYGLTEANGMGTMCRPEDDAVTVATTCGRPF 346 RFAVTGAAT+PVVL+ERMQSELDIDIVLTAYGLTEA G GTMCR +DDAVTVATT GRP Sbjct 300 RFAVTGAATIPVVLIERMQSELDIDIVLTAYGLTEAAGFGTMCRADDDAVTVATTSGRPI 359 Query 347 ADFELRIADDGEVLLRGPNVMVGYLDDTEATAAAIDADGWLHTGDIGAVDQAGNLRITDR 406 ADFELRI D EVLLRGPNVM+GYLDD EATAAAIDADGWLHTGD+G +D AGNL+ITDR Sbjct 360 ADFELRIGDQSEVLLRGPNVMLGYLDDPEATAAAIDADGWLHTGDVGELDDAGNLKITDR 419 Query 407 LKDMYICGGFNVYPAEVEQVLARMDGVADAAVIGVPDQRLGEVGRAFVVARPGTGLDEAS 466 LKDMYICGGFNVYPAE+EQVLAR+DGVA+AAVIGVPD+RLGEVG+AFVV P LDE + Sbjct 420 LKDMYICGGFNVYPAEIEQVLARLDGVAEAAVIGVPDERLGEVGKAFVVRLPSAELDEKT 479 Query 467 VIAYTREHLANFKTPRSVRFVDVLPRNAAGKVSKPQLRE 505 VI Y REHLANFKTPR+V F+D LPRN GKV KP LR+ Sbjct 480 VIDYAREHLANFKTPRTVEFLDALPRNPGGKVVKPLLRQ 518 >gi|116266962|gb|ABJ96327.1| putative fatty-acid CoA synthetase [Mycobacterium smegmatis str. MC2 155] Length=504 Score = 774 bits (1998), Expect = 0.0, Method: Compositional matrix adjust. Identities = 387/502 (78%), Positives = 430/502 (86%), Gaps = 1/502 (0%) Query 5 LRTVPAALDRLVRQLPDHTALIAEDRRFTSTELRDAVYGAAAALIALGVEPADRVAIWSP 64 +RTVPA LDR+ Q PDH A++ DRR T +LRD V AAAA+I LGVEP DR+AIWSP Sbjct 1 MRTVPAVLDRIAAQFPDHDAVVCPDRRLTYAQLRDEVRRAAAAMITLGVEPGDRIAIWSP 60 Query 65 NTWHWVVACLAIHHAGAAVVPLNTRYTATEATDILDRAGAPVLFAAGLFLGADRAAGLDR 124 NTWHWVVA LA H+AG VVPLNTRYTA+EATDIL R GAP+L A+G FLGAD+ A LDR Sbjct 61 NTWHWVVASLATHYAGGVVVPLNTRYTASEATDILLRTGAPLLIASGKFLGADKTADLDR 120 Query 125 AALPALRHVVRVPVEADDGTWDEFIATGAGA-LDAVAARAAAVAPQDVSDILFTSGTTGR 183 A LPALRH+VRVP++ +DGTWDEFIA A L V ARAAAV+P DVSDILFTSGTTGR Sbjct 121 ATLPALRHIVRVPIDENDGTWDEFIARADDATLAEVDARAAAVSPDDVSDILFTSGTTGR 180 Query 184 SKGVLCAHRQSLSASASWAANGKITSDDRYLCINPFFHNFGYKAGILACLQTGATLIPHV 243 SKGV CAHRQSL SA+WA G+++S DRYLCINPFFHNFGYKAGILACLQTGATL P + Sbjct 181 SKGVRCAHRQSLDGSAAWAECGQVSSTDRYLCINPFFHNFGYKAGILACLQTGATLYPML 240 Query 244 TFDPLHALRAIERHRITVLPGPPTIYQSLLDHPARKDFDLSSLRFAVTGAATVPVVLVER 303 TFDP ++A+ H+ITVLPGPPTIYQ+LLDHP R D+DLSSLRFAVTGAA VPVVL+ER Sbjct 241 TFDPEQTMKAVAEHKITVLPGPPTIYQTLLDHPRRGDYDLSSLRFAVTGAAVVPVVLIER 300 Query 304 MQSELDIDIVLTAYGLTEANGMGTMCRPEDDAVTVATTCGRPFADFELRIADDGEVLLRG 363 MQSELDIDIVLTAYGLTEA G GTMCRP+DDAVTVATTCGRP ADFELR+ D GEVLLRG Sbjct 301 MQSELDIDIVLTAYGLTEAAGFGTMCRPDDDAVTVATTCGRPIADFELRLDDSGEVLLRG 360 Query 364 PNVMVGYLDDTEATAAAIDADGWLHTGDIGAVDQAGNLRITDRLKDMYICGGFNVYPAEV 423 PNVM+GYLDD ATAAAIDADGWLHTGDIG +D AGNL ITDRLKDMYICGGFNVYPAE+ Sbjct 361 PNVMLGYLDDEAATAAAIDADGWLHTGDIGKLDAAGNLTITDRLKDMYICGGFNVYPAEI 420 Query 424 EQVLARMDGVADAAVIGVPDQRLGEVGRAFVVARPGTGLDEASVIAYTREHLANFKTPRS 483 EQVLAR+DGVA++AVIGVPD+RLGEVG+AFVVA+PG LD+A+VIAY REHLANFK PRS Sbjct 421 EQVLARLDGVAESAVIGVPDERLGEVGKAFVVAKPGAQLDQATVIAYAREHLANFKVPRS 480 Query 484 VRFVDVLPRNAAGKVSKPQLRE 505 V F+D LPRN GKV KP LRE Sbjct 481 VEFLDALPRNPGGKVVKPALRE 502 >gi|108801657|ref|YP_641854.1| long-chain-fatty-acid--CoA ligase [Mycobacterium sp. MCS] gi|119870808|ref|YP_940760.1| long-chain-fatty-acid--CoA ligase [Mycobacterium sp. KMS] gi|126437643|ref|YP_001073334.1| long-chain-fatty-acid--CoA ligase [Mycobacterium sp. JLS] gi|108772076|gb|ABG10798.1| AMP-dependent synthetase and ligase [Mycobacterium sp. MCS] gi|119696897|gb|ABL93970.1| AMP-dependent synthetase and ligase [Mycobacterium sp. KMS] gi|126237443|gb|ABO00844.1| AMP-dependent synthetase and ligase [Mycobacterium sp. JLS] Length=506 Score = 769 bits (1986), Expect = 0.0, Method: Compositional matrix adjust. Identities = 377/500 (76%), Positives = 425/500 (85%), Gaps = 1/500 (0%) Query 6 RTVPAALDRLVRQLPDHTALIAEDRRFTSTELRDAVYGAAAALIALGVEPADRVAIWSPN 65 RT+PA LDR+ Q DH A++ +DRR T +LRD V AAAA+I LG+ DRVAIWSPN Sbjct 6 RTIPAVLDRIAEQFSDHEAVVTDDRRLTYAQLRDEVRRAAAAMIDLGIAAGDRVAIWSPN 65 Query 66 TWHWVVACLAIHHAGAAVVPLNTRYTATEATDILDRAGAPVLFAAGLFLGADRAAGLDRA 125 TWHWVVA LA +AG VVPLNTRYTA+EA+DIL R AP+L AG FLGADR+A LDR+ Sbjct 66 TWHWVVAALATTYAGGVVVPLNTRYTASEASDILARTAAPLLITAGKFLGADRSADLDRS 125 Query 126 ALPALRHVVRVPVEADDGTWDEFIATGAGALDAVAARAAAVAPQDVSDILFTSGTTGRSK 185 ALPALRH+VRVP+E DGTWD+F++ G L A ARAAAV P DV+DILFTSGTTGRSK Sbjct 126 ALPALRHIVRVPIETADGTWDDFVSRGTD-LAAADARAAAVRPDDVADILFTSGTTGRSK 184 Query 186 GVLCAHRQSLSASASWAANGKITSDDRYLCINPFFHNFGYKAGILACLQTGATLIPHVTF 245 GVLCAHRQSL A A+WA G++TS DRYLCINPFFHNFGYKAGIL CLQTGATLIP +TF Sbjct 185 GVLCAHRQSLDAPAAWAECGQLTSSDRYLCINPFFHNFGYKAGILTCLQTGATLIPQLTF 244 Query 246 DPLHALRAIERHRITVLPGPPTIYQSLLDHPARKDFDLSSLRFAVTGAATVPVVLVERMQ 305 DP A+ A+ RITVLPGPPTIYQ++LDHP R ++DL+SLRFAVTGAA VPVVL+ERMQ Sbjct 245 DPEKAMAAVAEQRITVLPGPPTIYQTILDHPKRAEYDLTSLRFAVTGAAVVPVVLIERMQ 304 Query 306 SELDIDIVLTAYGLTEANGMGTMCRPEDDAVTVATTCGRPFADFELRIADDGEVLLRGPN 365 SELDIDIVLTAYGLTEA+G GTMCR +DDAVTVATTCGRP A FELRI D GEVLLRGPN Sbjct 305 SELDIDIVLTAYGLTEASGFGTMCRADDDAVTVATTCGRPIAGFELRIGDSGEVLLRGPN 364 Query 366 VMVGYLDDTEATAAAIDADGWLHTGDIGAVDQAGNLRITDRLKDMYICGGFNVYPAEVEQ 425 VM+GYLDD EATAAAID DGWLHTGD+G VD+ GNLRITDRLKDMYICGGFNVYPAE+EQ Sbjct 365 VMLGYLDDPEATAAAIDPDGWLHTGDVGTVDERGNLRITDRLKDMYICGGFNVYPAEIEQ 424 Query 426 VLARMDGVADAAVIGVPDQRLGEVGRAFVVARPGTGLDEASVIAYTREHLANFKTPRSVR 485 VLAR+DGVA++AVIGVPD+RLGEVG+AFVVA+PG LDE +VIAY R+HLANFKTPRSV Sbjct 425 VLARLDGVAESAVIGVPDERLGEVGKAFVVAKPGANLDEQAVIAYARDHLANFKTPRSVE 484 Query 486 FVDVLPRNAAGKVSKPQLRE 505 F+DVLPRN GKV KP LR+ Sbjct 485 FLDVLPRNPGGKVVKPLLRK 504 >gi|145222072|ref|YP_001132750.1| long-chain-fatty-acid--CoA ligase [Mycobacterium gilvum PYR-GCK] gi|315446186|ref|YP_004079065.1| acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II [Mycobacterium sp. Spyr1] gi|145214558|gb|ABP43962.1| AMP-dependent synthetase and ligase [Mycobacterium gilvum PYR-GCK] gi|315264489|gb|ADU01231.1| acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II [Mycobacterium sp. Spyr1] Length=512 Score = 764 bits (1974), Expect = 0.0, Method: Compositional matrix adjust. Identities = 382/502 (77%), Positives = 426/502 (85%), Gaps = 2/502 (0%) Query 6 RTVPAALDRLVRQLPDHTALIAEDRRFTSTELRDAVYGAAAALIALGVEPADRVAIWSPN 65 RT PA L+R+ R+LPD A++ R T LR V AAAA+I LG+EP DRVAIWSPN Sbjct 6 RTTPAVLERIARELPDQPAVVTAQRTLTYFGLRSEVLHAAAAMIDLGIEPGDRVAIWSPN 65 Query 66 TWHWVVACLAIHHAGAAVVPLNTRYTATEATDILDRAGAPVLFAAGLFLGADRAAGLDRA 125 TWHWVVA LAIHHAG +VPLNTRYTA+EA DIL R GAP+LFA+G FLGAD+AA +DR Sbjct 66 TWHWVVASLAIHHAGGVLVPLNTRYTASEAEDILARTGAPLLFASGAFLGADKAASVDRD 125 Query 126 ALPALRHVVRVPVEADDGTWDEFIATGAG--ALDAVAARAAAVAPQDVSDILFTSGTTGR 183 +LPALRH+VR+PV+ DDGTWDE+IA GA AL AV ARAAAV DVSDILFTSGTTGR Sbjct 126 SLPALRHIVRIPVDTDDGTWDEYIARGAKEEALAAVGARAAAVTADDVSDILFTSGTTGR 185 Query 184 SKGVLCAHRQSLSASASWAANGKITSDDRYLCINPFFHNFGYKAGILACLQTGATLIPHV 243 SKGV CA RQSL ASA+WAA G++T DDRYLCINPFFHNFGYKAGILACLQTGATL P + Sbjct 186 SKGVRCAQRQSLDASAAWAACGQLTRDDRYLCINPFFHNFGYKAGILACLQTGATLYPEL 245 Query 244 TFDPLHALRAIERHRITVLPGPPTIYQSLLDHPARKDFDLSSLRFAVTGAATVPVVLVER 303 TFDP ++A++ HRITVLPGPPTIYQ+LLDHP R +FDLSSLRFAVTGAAT+PVVL+ER Sbjct 246 TFDPGETMQAVQEHRITVLPGPPTIYQTLLDHPRRSEFDLSSLRFAVTGAATIPVVLIER 305 Query 304 MQSELDIDIVLTAYGLTEANGMGTMCRPEDDAVTVATTCGRPFADFELRIADDGEVLLRG 363 MQSELDIDIVLTAYGLTEA G GTMCR +DDAVTVATT GRP ADFELRI + GEVLLRG Sbjct 306 MQSELDIDIVLTAYGLTEAAGFGTMCRADDDAVTVATTSGRPIADFELRIGESGEVLLRG 365 Query 364 PNVMVGYLDDTEATAAAIDADGWLHTGDIGAVDQAGNLRITDRLKDMYICGGFNVYPAEV 423 PNVM+GYLDD EATAAAID DGWLHTGD+G +D AGNL+ITDRLKDMYICGGFNVYPAE+ Sbjct 366 PNVMLGYLDDPEATAAAIDGDGWLHTGDVGELDPAGNLKITDRLKDMYICGGFNVYPAEI 425 Query 424 EQVLARMDGVADAAVIGVPDQRLGEVGRAFVVARPGTGLDEASVIAYTREHLANFKTPRS 483 EQVLAR+DGVA+AAVIGVPD RLGEVG+AFVV PG LDE +VI + REHLANFKTPRS Sbjct 426 EQVLARLDGVAEAAVIGVPDDRLGEVGKAFVVTLPGAELDEKTVIDHAREHLANFKTPRS 485 Query 484 VRFVDVLPRNAAGKVSKPQLRE 505 V F+D LPRN GKV KP LR+ Sbjct 486 VEFLDALPRNPGGKVVKPLLRQ 507 >gi|333992357|ref|YP_004524971.1| fatty-acid-CoA ligase [Mycobacterium sp. JDM601] gi|333488325|gb|AEF37717.1| fatty-acid-CoA ligase FadD3 [Mycobacterium sp. JDM601] Length=515 Score = 720 bits (1858), Expect = 0.0, Method: Compositional matrix adjust. Identities = 383/508 (76%), Positives = 418/508 (83%), Gaps = 8/508 (1%) Query 6 RTVPAALDRLVRQLPDHTALIAEDRRFTSTELRDAVYGAAAALIALGVEPADRVAIWSPN 65 +T PAALD + R LPDH AL+ ED RF+ LRD V AAAALIALGV P DRVA+WSPN Sbjct 6 QTTPAALDHIARTLPDHDALVTEDDRFSYARLRDEVRRAAAALIALGVAPGDRVALWSPN 65 Query 66 TWHWVVACLAIHHAGAAVVPLNTRYTATEATDILDRAGAPVLFAAGLFLGADRAAGLDRA 125 TWHWV++CL H+AG +VPLNTRYTA EATDIL R+ A VL G FL ADR LDR Sbjct 66 TWHWVISCLGTHYAGGVLVPLNTRYTAPEATDILARSKAKVLVGMGRFLKADRLGELDRD 125 Query 126 ALPALRHVVRVPVEADDGTWDEFIATGAGALD-AVAARAAAVAPQDVSDILFTSGTTGRS 184 LP LRHVVRVPVE DGTWDEFIA GA D + ARAAAV P D+SDILFTSGTTGRS Sbjct 126 ELPELRHVVRVPVELTDGTWDEFIAAGASVTDDEIDARAAAVGPDDLSDILFTSGTTGRS 185 Query 185 KGVLCAHRQSLSASASWAANGKITSDDRYLCINPFFHNFGYKAGILACLQTGATLIPHVT 244 KGVLCAHRQSL+ A+WA G++T+DDRYLCINPFFHNFGYKAGILACLQTGATLIP +T Sbjct 186 KGVLCAHRQSLAGPAAWAECGQMTADDRYLCINPFFHNFGYKAGILACLQTGATLIPQLT 245 Query 245 FDPLHALRAIERHRITVLPGPPTIYQSLLDHPARKDFDLSSLRFAVTGAATVPVVLVERM 304 FDP ALRAI HRITVLPGPPTIYQ+LLDHP R DLSSLRFAVTGAATVPVVL+ERM Sbjct 246 FDPAGALRAIAEHRITVLPGPPTIYQTLLDHPDRDRHDLSSLRFAVTGAATVPVVLIERM 305 Query 305 QSELDIDIVLTAYGLTEANGMGTMCRPEDDAVTVATTCGRPFADFELRI-----ADDGEV 359 Q+ELDIDIVLTAYGLTE+ G TMCRP+DDAVTVATTCGRP ADFELRI ++ GEV Sbjct 306 QNELDIDIVLTAYGLTESGGFATMCRPDDDAVTVATTCGRPIADFELRIDHGPDSEAGEV 365 Query 360 LLRGPNVMVGYLDDTEATAAAIDADGWLHTGDIGAVDQAGNLRITDRLKDMYICGGFNVY 419 LLR N+M+GYLDD +ATAAAIDADGWLHTGD+G VD AGNLRITDRLKDMYICGGFNVY Sbjct 366 LLRSANIMLGYLDDDDATAAAIDADGWLHTGDVGTVDAAGNLRITDRLKDMYICGGFNVY 425 Query 420 PAEVEQVLARMDGVADAAVIGVPDQRLGEVGRAFVVARPGT--GLDEASVIAYTREHLAN 477 PAE+EQVLAR+DGVAD AVIGVPD+RLGEVGRAF+V R G+ LDE VIAY REHLAN Sbjct 426 PAEIEQVLARLDGVADVAVIGVPDERLGEVGRAFIVRRAGSDEALDEQKVIAYAREHLAN 485 Query 478 FKTPRSVRFVDVLPRNAAGKVSKPQLRE 505 FK PRSV F D LPRN GKV K +LRE Sbjct 486 FKAPRSVTFADSLPRNPGGKVVKHELRE 513 >gi|289752274|ref|ZP_06511652.1| fatty-acid-CoA ligase fadD3 [Mycobacterium tuberculosis T92] gi|289692861|gb|EFD60290.1| fatty-acid-CoA ligase fadD3 [Mycobacterium tuberculosis T92] Length=352 Score = 713 bits (1840), Expect = 0.0, Method: Compositional matrix adjust. Identities = 350/352 (99%), Positives = 351/352 (99%), Gaps = 0/352 (0%) Query 156 LDAVAARAAAVAPQDVSDILFTSGTTGRSKGVLCAHRQSLSASASWAANGKITSDDRYLC 215 +DAVAARA AVAPQDVSDILFTSGTTGRSKGVLCAHRQSLSASASWAANGKITSDDRYLC Sbjct 1 MDAVAARAVAVAPQDVSDILFTSGTTGRSKGVLCAHRQSLSASASWAANGKITSDDRYLC 60 Query 216 INPFFHNFGYKAGILACLQTGATLIPHVTFDPLHALRAIERHRITVLPGPPTIYQSLLDH 275 INPFFHNFGYKAGILACLQTGATLIPHVTFDPLHALRAIERHRITVLPGPPTIYQSLLDH Sbjct 61 INPFFHNFGYKAGILACLQTGATLIPHVTFDPLHALRAIERHRITVLPGPPTIYQSLLDH 120 Query 276 PARKDFDLSSLRFAVTGAATVPVVLVERMQSELDIDIVLTAYGLTEANGMGTMCRPEDDA 335 PARKDFDLSSLRFAVTGAATVPVVLVERMQSELDIDIVLTAYGLTEANGMGTMCRPEDDA Sbjct 121 PARKDFDLSSLRFAVTGAATVPVVLVERMQSELDIDIVLTAYGLTEANGMGTMCRPEDDA 180 Query 336 VTVATTCGRPFADFELRIADDGEVLLRGPNVMVGYLDDTEATAAAIDADGWLHTGDIGAV 395 VTVATTCGRPFADFELRIADDGEVLLRGPNVMVGYLDDTEATAAAIDADGWLHTGDIGAV Sbjct 181 VTVATTCGRPFADFELRIADDGEVLLRGPNVMVGYLDDTEATAAAIDADGWLHTGDIGAV 240 Query 396 DQAGNLRITDRLKDMYICGGFNVYPAEVEQVLARMDGVADAAVIGVPDQRLGEVGRAFVV 455 DQAGNLRITDRLKDMYICGGFNVYPAEVEQVLARMDGVADAAVIGVPDQRLGEVGRAFVV Sbjct 241 DQAGNLRITDRLKDMYICGGFNVYPAEVEQVLARMDGVADAAVIGVPDQRLGEVGRAFVV 300 Query 456 ARPGTGLDEASVIAYTREHLANFKTPRSVRFVDVLPRNAAGKVSKPQLRELG 507 ARPGTGLDEASVIAYTREHLANFKTPRSVRFVDVLPRNAAGKVSKPQLRELG Sbjct 301 ARPGTGLDEASVIAYTREHLANFKTPRSVRFVDVLPRNAAGKVSKPQLRELG 352 >gi|169627699|ref|YP_001701348.1| fatty-acid-CoA ligase FadD [Mycobacterium abscessus ATCC 19977] gi|169239666|emb|CAM60694.1| Probable fatty-acid-CoA ligase FadD [Mycobacterium abscessus] Length=530 Score = 667 bits (1722), Expect = 0.0, Method: Compositional matrix adjust. Identities = 331/508 (66%), Positives = 391/508 (77%), Gaps = 8/508 (1%) Query 7 TVPAALDRLVRQLPDHTALIAEDRRFTSTELRDAVYGAAAALIALGVEPADRVAIWSPNT 66 T+PAALD+ + + AL A+ + +ELR AAALIALGVE R+AIWSPN+ Sbjct 11 TIPAALDQAAARFGERDALYADGSWLSFSELRARARRFAAALIALGVEHGQRLAIWSPNS 70 Query 67 WHWVVACLAIHHAGAAVVPLNTRYTATEATDILDRAGAPVLFAAGLFLGADRAAGLDRAA 126 WHW +ACL +AGAAVVP+NTRYT EATDIL R+ A VL + G FLG DR LD ++ Sbjct 71 WHWPIACLGGQYAGAAVVPMNTRYTVDEATDILQRSHARVLVSVGKFLGTDRIEQLDTSS 130 Query 127 LPALRHVVRVPVE-ADDGTWDEFIATGAGALDA-VAARAAAVAPQDVSDILFTSGTTGRS 184 LP LRH+VRV VE D+ WD F+A G G D + R AAV+ +D+SDILFTSGTTGRS Sbjct 131 LPDLRHIVRVAVEDGDESGWDAFVAHGDGVSDGDIDTRKAAVSSEDISDILFTSGTTGRS 190 Query 185 KGVLCAHRQSLSASASWAANGKITSDDRYLCINPFFHNFGYKAGILACLQTGATLIPHVT 244 KGVLC HRQ L+AS +WA G+ T +DRYLC+NPFFHNFGYKAGILACLQTGA L+P +T Sbjct 191 KGVLCMHRQPLAASLAWATYGEFTENDRYLCVNPFFHNFGYKAGILACLQTGAALMPQLT 250 Query 245 FDPLHALRAIERHRITVLPGPPTIYQSLLDHPARKDFDLSSLRFAVTGAATVPVVLVERM 304 FDP A+ A++ H+ITVLPG PTI+Q LLDHPARK++DL+SLR++VTGAA VPVVL+ERM Sbjct 251 FDPEKAMAAVQEHKITVLPGAPTIFQMLLDHPARKNYDLTSLRYSVTGAAVVPVVLIERM 310 Query 305 QSELDIDIVLTAYGLTEANGMGTMCRPEDDAVTVATTCGRPFADFELRI------ADDGE 358 QSELD D+VLTAYGLTE G T+CR +DDAVTVATTCGRP +ELRI D+GE Sbjct 311 QSELDFDLVLTAYGLTETQGFATICRSDDDAVTVATTCGRPMLGYELRIDGAEKPGDEGE 370 Query 359 VLLRGPNVMVGYLDDTEATAAAIDADGWLHTGDIGAVDQAGNLRITDRLKDMYICGGFNV 418 VLLR NVM GYLDD +ATA AID DGWLHTGDIG +D GNL ITDRLKDMYICGGFNV Sbjct 371 VLLRSANVMKGYLDDPKATAEAIDDDGWLHTGDIGKLDARGNLTITDRLKDMYICGGFNV 430 Query 419 YPAEVEQVLARMDGVADAAVIGVPDQRLGEVGRAFVVARPGTGLDEASVIAYTREHLANF 478 YPAE+EQVL R+DGVAD AVIGVPD RLGEVG+A++V +PG L+ SVI Y+ +H+ANF Sbjct 431 YPAEIEQVLMRLDGVADVAVIGVPDARLGEVGKAYIVLKPGATLNADSVIEYSAKHVANF 490 Query 479 KTPRSVRFVDVLPRNAAGKVSKPQLREL 506 K PR V F+D LPRN GKV KP LR + Sbjct 491 KKPRFVDFLDELPRNLGGKVVKPTLRAM 518 >gi|289571803|ref|ZP_06452030.1| fatty-acid-CoA ligase fadD3 [Mycobacterium tuberculosis T17] gi|289545557|gb|EFD49205.1| fatty-acid-CoA ligase fadD3 [Mycobacterium tuberculosis T17] Length=321 Score = 656 bits (1692), Expect = 0.0, Method: Compositional matrix adjust. Identities = 320/321 (99%), Positives = 321/321 (100%), Gaps = 0/321 (0%) Query 187 VLCAHRQSLSASASWAANGKITSDDRYLCINPFFHNFGYKAGILACLQTGATLIPHVTFD 246 +LCAHRQSLSASASWAANGKITSDDRYLCINPFFHNFGYKAGILACLQTGATLIPHVTFD Sbjct 1 MLCAHRQSLSASASWAANGKITSDDRYLCINPFFHNFGYKAGILACLQTGATLIPHVTFD 60 Query 247 PLHALRAIERHRITVLPGPPTIYQSLLDHPARKDFDLSSLRFAVTGAATVPVVLVERMQS 306 PLHALRAIERHRITVLPGPPTIYQSLLDHPARKDFDLSSLRFAVTGAATVPVVLVERMQS Sbjct 61 PLHALRAIERHRITVLPGPPTIYQSLLDHPARKDFDLSSLRFAVTGAATVPVVLVERMQS 120 Query 307 ELDIDIVLTAYGLTEANGMGTMCRPEDDAVTVATTCGRPFADFELRIADDGEVLLRGPNV 366 ELDIDIVLTAYGLTEANGMGTMCRPEDDAVTVATTCGRPFADFELRIADDGEVLLRGPNV Sbjct 121 ELDIDIVLTAYGLTEANGMGTMCRPEDDAVTVATTCGRPFADFELRIADDGEVLLRGPNV 180 Query 367 MVGYLDDTEATAAAIDADGWLHTGDIGAVDQAGNLRITDRLKDMYICGGFNVYPAEVEQV 426 MVGYLDDTEATAAAIDADGWLHTGDIGAVDQAGNLRITDRLKDMYICGGFNVYPAEVEQV Sbjct 181 MVGYLDDTEATAAAIDADGWLHTGDIGAVDQAGNLRITDRLKDMYICGGFNVYPAEVEQV 240 Query 427 LARMDGVADAAVIGVPDQRLGEVGRAFVVARPGTGLDEASVIAYTREHLANFKTPRSVRF 486 LARMDGVADAAVIGVPDQRLGEVGRAFVVARPGTGLDEASVIAYTREHLANFKTPRSVRF Sbjct 241 LARMDGVADAAVIGVPDQRLGEVGRAFVVARPGTGLDEASVIAYTREHLANFKTPRSVRF 300 Query 487 VDVLPRNAAGKVSKPQLRELG 507 VDVLPRNAAGKVSKPQLRELG Sbjct 301 VDVLPRNAAGKVSKPQLRELG 321 >gi|41406604|ref|NP_959440.1| acyl-CoA synthase [Mycobacterium avium subsp. paratuberculosis K-10] gi|41394953|gb|AAS02823.1| FadD3_1 [Mycobacterium avium subsp. paratuberculosis K-10] Length=421 Score = 621 bits (1602), Expect = 7e-176, Method: Compositional matrix adjust. Identities = 340/409 (84%), Positives = 360/409 (89%), Gaps = 5/409 (1%) Query 1 LINDLRTVPAALDRLVRQLPDHTALIAEDRRFTSTELRDAVYGAAAALIALGVEPADRVA 60 + D RTVPAALDRL R+LPDH ALI EDR FT+ LRD V+ AAAALI LGV DRVA Sbjct 1 MTTDPRTVPAALDRLARRLPDHDALITEDRSFTAAALRDEVHRAAAALIELGVRAGDRVA 60 Query 61 IWSPNTWHWVVACLAIHHAGAAVVPLNTRYTATEATDILDRAGAPVLFAAGLFLGADRAA 120 IWSPNTWHWVVACLAIHHAGAA+VPLNTRYTA EA DIL R GAPVLF G FLG DR A Sbjct 61 IWSPNTWHWVVACLAIHHAGAAMVPLNTRYTAAEAGDILARVGAPVLFGMGRFLGHDRLA 120 Query 121 GLDRAALPALRHVVRVPVEADD---GTWDEFIATGAGALDAVAARAAAVAPQDVSDILFT 177 LDRAALPALRH+VR+P+EADD G+WDEFIA G L AVA RAAAV P DVSDILFT Sbjct 121 DLDRAALPALRHIVRIPIEADDPVPGSWDEFIAHGTD-LGAVAERAAAVTPDDVSDILFT 179 Query 178 SGTTGRSKGVLCAHRQSLSASASWAANGKITSDDRYLCINPFFHNFGYKAGILACLQTGA 237 SGTTGRSKGVLCAHRQSLSASASWAANGKITSDDRYLCINPFFHNFGYKAGILACLQTGA Sbjct 180 SGTTGRSKGVLCAHRQSLSASASWAANGKITSDDRYLCINPFFHNFGYKAGILACLQTGA 239 Query 238 TLIPHVTFDPLHALRAIERHRITVLPGPPTIYQSLLDHPARKDFDLSSLRFAVTGAATVP 297 TLIPH+TFDPL AL+AIE+HRITVLPGPPTIYQ+LLDHPAR+D+DLSSLRFAVTGAATVP Sbjct 240 TLIPHLTFDPLRALQAIEQHRITVLPGPPTIYQTLLDHPARRDYDLSSLRFAVTGAATVP 299 Query 298 VVLVERMQSELDIDIVLTAYGLTEANGMGTMCRPEDDAVTVATTCGRPFADFELRIADDG 357 VVLVERMQSELDIDIVLTAYGLTEANGMGTMCR +DDAVTVATTCGRPFADFELRI D G Sbjct 300 VVLVERMQSELDIDIVLTAYGLTEANGMGTMCRADDDAVTVATTCGRPFADFELRIDDSG 359 Query 358 EVLLRGPNVMVGYLDDTEATAAAIDADGWLHTGDIGAVDQAGNLRITDR 406 EVLLRGPNVM+GYLDD +ATAAAIDADGWLHTGDI A +G+ R R Sbjct 360 EVLLRGPNVMLGYLDDPDATAAAIDADGWLHTGDI-AFPTSGSARWAAR 407 >gi|54022447|ref|YP_116689.1| long-chain-fatty-acid--CoA ligase [Nocardia farcinica IFM 10152] gi|54013955|dbj|BAD55325.1| putative acyl-CoA synthetase [Nocardia farcinica IFM 10152] Length=518 Score = 586 bits (1511), Expect = 3e-165, Method: Compositional matrix adjust. Identities = 318/511 (63%), Positives = 370/511 (73%), Gaps = 12/511 (2%) Query 6 RTVPAALDRLVRQLPDHTALIAEDRRFTSTELRDAVYGAAAALIALGVEPADRVAIWSPN 65 +T P AL R AL + R T+L V A ALIA GV DRVAIWSPN Sbjct 6 QTTPMALHDAARTHGAAPALADGEVRLDWTQLLAEVQRTARALIARGVRRGDRVAIWSPN 65 Query 66 TWHWVVACLAIHHAGAAVVPLNTRYTATEATDILDRAGAPVLFAAGLFLGADRAAGLDRA 125 T+HWVVA LA H+AGAA+VPLNTRY A EA D+L R LF AG FLG DR L RA Sbjct 66 TYHWVVAALAAHYAGAALVPLNTRYVADEAADVLGRVRPAALFVAGTFLGRDRLTEL-RA 124 Query 126 ALP--ALRHVVRVPVE--------ADDGTWDEFIATGAGALDAVA-ARAAAVAPQDVSDI 174 A P A+ VV +PVE A W + A A A RA V P+D+SDI Sbjct 125 AAPDLAIETVVVIPVEPGTSVPTDARTLNWPDLDAAAETVTPAEAEQRAREVDPEDLSDI 184 Query 175 LFTSGTTGRSKGVLCAHRQSLSASASWAANGKITSDDRYLCINPFFHNFGYKAGILACLQ 234 LFTSGTTGRSKG L AHRQ++S +WA + +DDRYL +NPFFHNFGYKAG LAC+ Sbjct 185 LFTSGTTGRSKGTLVAHRQAMSVVRAWAERATLRADDRYLVVNPFFHNFGYKAGFLACMV 244 Query 235 TGATLIPHVTFDPLHALRAIERHRITVLPGPPTIYQSLLDHPARKDFDLSSLRFAVTGAA 294 TGAT++P VTFD ++ I RITVLPGPPTIYQ++LD P R+ +DLSSLR AVTGAA Sbjct 245 TGATIVPQVTFDVPRTMQLIGSERITVLPGPPTIYQTILDFPGRESYDLSSLRVAVTGAA 304 Query 295 TVPVVLVERMQSELDIDIVLTAYGLTEANGMGTMCRPEDDAVTVATTCGRPFADFELRIA 354 TVPVVL+ERM+SEL D+VLTAYGL+E+ G GTMC P+DDAVTVA TCGRP ADFEL+++ Sbjct 305 TVPVVLIERMRSELAFDVVLTAYGLSESAGFGTMCSPDDDAVTVANTCGRPIADFELKLS 364 Query 355 DDGEVLLRGPNVMVGYLDDTEATAAAIDADGWLHTGDIGAVDQAGNLRITDRLKDMYICG 414 + GEVLLRGPNVM+GYLDD EATA IDA+GWLHTGDIG VD+ G L+ITDRLKDMYI G Sbjct 365 EAGEVLLRGPNVMLGYLDDPEATAETIDAEGWLHTGDIGTVDERGYLKITDRLKDMYISG 424 Query 415 GFNVYPAEVEQVLARMDGVADAAVIGVPDQRLGEVGRAFVVARPGTGLDEASVIAYTREH 474 GFNVYPAEVEQ LAR+DGVA++AVIGVPD+R+GEVG+A+VV +PG L E VIA+ + Sbjct 425 GFNVYPAEVEQALARLDGVAESAVIGVPDERMGEVGKAYVVRKPGAELTEEQVIAHAKTV 484 Query 475 LANFKTPRSVRFVDVLPRNAAGKVSKPQLRE 505 LANFK PR V F D LP +AAGKV K QLRE Sbjct 485 LANFKVPRFVEFRDQLPYSAAGKVLKRQLRE 515 >gi|111021567|ref|YP_704539.1| CoA ligase [Rhodococcus jostii RHA1] gi|110821097|gb|ABG96381.1| CoA ligase [Rhodococcus jostii RHA1] Length=515 Score = 582 bits (1499), Expect = 6e-164, Method: Compositional matrix adjust. Identities = 305/507 (61%), Positives = 363/507 (72%), Gaps = 9/507 (1%) Query 7 TVPAALDRLVRQLPDHTALIAEDRRFTSTELRDAVYGAAAALIALGVEPADRVAIWSPNT 66 T P+AL R R+ + TA+ D R T T+L D V AAAL + V P D VA+WSPNT Sbjct 7 TTPSALKRAAREFGELTAVADGDVRLTFTQLHDRVRDFAAALSSQDVRPGDHVAVWSPNT 66 Query 67 WHWVVACLAIHHAGAAVVPLNTRYTATEATDILDRAGAPVLFAAGLFLGADRAAGL-DRA 125 +HWVVA L IH+AGA +VP+NTRYTATEA DIL+R L AG FLG DR A L D + Sbjct 67 YHWVVAALGIHYAGATLVPINTRYTATEALDILERTKTTALVVAGNFLGTDRYASLRDES 126 Query 126 ALPALRHVVRVPVEADDGT------WDEFIATG-AGALDAVAARAAAVAPQDVSDILFTS 178 + L VVRVPV+ D +D+F+A ARAAAV+P DVSD++FTS Sbjct 127 STFDLPTVVRVPVDGGDAELPGVFDFDDFLALADEDTRAEADARAAAVSPDDVSDVMFTS 186 Query 179 GTTGRSKGVLCAHRQSLSASASWAANGKITSDDRYLCINPFFHNFGYKAGILACLQTGAT 238 GTTGRSKGV+ AHRQS+ + +W ++TSDD YL INPFFH FGYKAG L CL GAT Sbjct 187 GTTGRSKGVMSAHRQSVGIAQAWGECAEVTSDDNYLIINPFFHTFGYKAGFLVCLLNGAT 246 Query 239 LIPHVTFDPLHALRAIERHRITVLPGPPTIYQSLLDHPARKDFDLSSLRFAVTGAATVPV 298 ++P FD + + +ITVLPG PTI+QS+LDHP R +DLSSLR A+TGAA VPV Sbjct 247 VVPMAVFDVPKVMATVHDEQITVLPGAPTIFQSILDHPDRPKYDLSSLRVAITGAAAVPV 306 Query 299 VLVERMQSELDIDIVLTAYGLTEANGMGTMCRPEDDAVTVATTCGRPFADFELRIADDGE 358 LVERMQSEL D VLTAYG TEA + TMCR +DD VTV+TT GR E+RI D GE Sbjct 307 ALVERMQSELSFDAVLTAYGQTEAVVV-TMCRTDDDPVTVSTTSGRAIPGMEVRIGDQGE 365 Query 359 VLLRGPNVMVGYLDDTEATAAAIDADGWLHTGDIGAVDQAGNLRITDRLKDMYICGGFNV 418 +L+RG NVM+GYLDD E+TA IDADGWLHTGD+G +D G + ITDRLKDMYI GGFNV Sbjct 366 ILVRGENVMLGYLDDPESTAKTIDADGWLHTGDVGTLDDRGYVDITDRLKDMYISGGFNV 425 Query 419 YPAEVEQVLARMDGVADAAVIGVPDQRLGEVGRAFVVARPGTGLDEASVIAYTREHLANF 478 YPAEVE LAR+DGVA++AVIGVPD+R+GEVGRA+VVA+PG L E V+A+ +E LANF Sbjct 426 YPAEVENALARLDGVAESAVIGVPDERMGEVGRAYVVAKPGVTLAEDDVVAFCKERLANF 485 Query 479 KTPRSVRFVDVLPRNAAGKVSKPQLRE 505 K PRSVRFVD LPRN +GKV K LRE Sbjct 486 KVPRSVRFVDSLPRNPSGKVMKNVLRE 512 >gi|343924359|ref|ZP_08763909.1| putative fatty-acid--CoA ligase [Gordonia alkanivorans NBRC 16433] gi|343765691|dbj|GAA10835.1| putative fatty-acid--CoA ligase [Gordonia alkanivorans NBRC 16433] Length=527 Score = 575 bits (1482), Expect = 6e-162, Method: Compositional matrix adjust. Identities = 291/515 (57%), Positives = 360/515 (70%), Gaps = 20/515 (3%) Query 7 TVPAALDRLVRQLPDHTALIA--------EDRRFTSTELRDAVYGAAAALIALGVEPADR 58 T PAAL R R PD A++ T + DAV AAAL+A G+E DR Sbjct 14 TTPAALQRAARSWPDGIAIVDGQWLPSTDPQLELTWAQFHDAVRTFAAALVASGIEAGDR 73 Query 59 VAIWSPNTWHWVVACLAIHHAGAAVVPLNTRYTATEATDILDRAGAPVLFAAGLFLGADR 118 VAIWSPN++HW +A L +H+AGA +VPLNTRYTA EA +I++R+ A L +G FLGAD Sbjct 74 VAIWSPNSFHWPIAALGVHYAGATLVPLNTRYTAGEAVEIVERSAARGLVVSGEFLGADH 133 Query 119 AAGL---DRAALPALRHVVRVPVEADDGT------WDEFIATGAG-ALDAVAARAAAVAP 168 AA L R LP L V+RVP+ T WD+F+ AL RAAAV+P Sbjct 134 AAELLRDHRGKLPDL--VIRVPLSGGSSTPDGAVDWDDFLGRQTDEALTEADRRAAAVSP 191 Query 169 QDVSDILFTSGTTGRSKGVLCAHRQSLSASASWAANGKITSDDRYLCINPFFHNFGYKAG 228 D+SDILFTSGTTG+SKGVL HRQ+L+ S W +N + DRYL +NP+FH FGYKAG Sbjct 192 DDISDILFTSGTTGKSKGVLATHRQTLNGSHGWGSNAGLHPGDRYLMVNPYFHTFGYKAG 251 Query 229 ILACLQTGATLIPHVTFDPLHALRAIERHRITVLPGPPTIYQSLLDHPARKDFDLSSLRF 288 IL C+ G T++P + P A++ + R TV PG PTI+Q++LD P R D DLSSLR Sbjct 252 ILPCVLFGVTMLPLAVYSPTEAMKLVSDERATVFPGAPTIFQTILDDPKRSDHDLSSLRI 311 Query 289 AVTGAATVPVVLVERMQSELDIDIVLTAYGLTEANGMGTMCRPEDDAVTVATTCGRPFAD 348 +TGA+ VPVVLV+R+Q++L +D V+TAYGLTEA+G + C P+DD TVA TCGR F Sbjct 312 VITGASIVPVVLVQRLQNDLGVDTVITAYGLTEASGFVSTCTPDDDDETVANTCGRAFPG 371 Query 349 FELRIADDGEVLLRGPNVMVGYLDDTEATAAAIDADGWLHTGDIGAVDQAGNLRITDRLK 408 E++++D GEVL RG NVMVGYLDD +ATA IDADGWLHTGDIG +D+ GNL ITDRLK Sbjct 372 MEIKLSDVGEVLARGENVMVGYLDDPQATAETIDADGWLHTGDIGTLDEHGNLTITDRLK 431 Query 409 DMYICGGFNVYPAEVEQVLARMDGVADAAVIGVPDQRLGEVGRAFVVARPGTGLDEASVI 468 DMYICGGFNVYPAE+EQ LAR+DGV ++AV+GVPD RLGEVGRA++ G LDEA VI Sbjct 432 DMYICGGFNVYPAEIEQTLARLDGVTESAVVGVPDDRLGEVGRAYLTVHDGADLDEAKVI 491 Query 469 AYTREHLANFKTPRSVRFVDVLPRNAAGKVSKPQL 503 A+ ++HLANFK PRSV FVD PRNA+GK+ K L Sbjct 492 AFAKQHLANFKVPRSVVFVDQFPRNASGKILKRNL 526 >gi|226363950|ref|YP_002781732.1| fatty-acid--CoA ligase [Rhodococcus opacus B4] gi|226242439|dbj|BAH52787.1| putative fatty-acid--CoA ligase [Rhodococcus opacus B4] Length=515 Score = 575 bits (1481), Expect = 8e-162, Method: Compositional matrix adjust. Identities = 303/508 (60%), Positives = 363/508 (72%), Gaps = 9/508 (1%) Query 6 RTVPAALDRLVRQLPDHTALIAEDRRFTSTELRDAVYGAAAALIALGVEPADRVAIWSPN 65 RT+P+A+ R+ + A+ D R T T+L D V AAAL + GV P D VA+WSPN Sbjct 6 RTIPSAVTHAAREYGELLAVSDGDVRLTFTQLHDRVRDFAAALCSQGVRPGDHVAVWSPN 65 Query 66 TWHWVVACLAIHHAGAAVVPLNTRYTATEATDILDRAGAPVLFAAGLFLGADRAAGL-DR 124 T+HWVVA L IH+AGA +VP+NTRYTA EA D+L+R A L AG+FLG DR A L D Sbjct 66 TYHWVVAALGIHYAGATLVPINTRYTAPEALDLLERTKATALVVAGMFLGTDRYAALRDA 125 Query 125 AALPALRHVVRVPVEADDG------TWDEFIA-TGAGALDAVAARAAAVAPQDVSDILFT 177 + L VVRVPV+ D +D+F+A G ARAAAV+P DVSD++FT Sbjct 126 SGTLDLPTVVRVPVDGGDAPTPGVVDFDDFLALAGDDTRAEADARAAAVSPDDVSDVMFT 185 Query 178 SGTTGRSKGVLCAHRQSLSASASWAANGKITSDDRYLCINPFFHNFGYKAGILACLQTGA 237 SGTTGRSKGV+ AHRQS+ + +W ++T +D YL INPFFH FGYKAG L CL G Sbjct 186 SGTTGRSKGVMSAHRQSVGIARAWGECAEVTPEDNYLIINPFFHTFGYKAGFLVCLLNGV 245 Query 238 TLIPHVTFDPLHALRAIERHRITVLPGPPTIYQSLLDHPARKDFDLSSLRFAVTGAATVP 297 T++P FD + + +ITVLPG PTI+QS+LDHP R ++DLSSLR A+TGAA VP Sbjct 246 TVVPMAVFDVPKVMATVHDEQITVLPGAPTIFQSILDHPDRPEYDLSSLRVAITGAAAVP 305 Query 298 VVLVERMQSELDIDIVLTAYGLTEANGMGTMCRPEDDAVTVATTCGRPFADFELRIADDG 357 V LVERMQSEL D VLTAYG TEA + TMCR +DD VTV+TT GR E+RI D G Sbjct 306 VALVERMQSELSFDAVLTAYGQTEAVVV-TMCRTDDDPVTVSTTSGRAIPGMEVRIGDHG 364 Query 358 EVLLRGPNVMVGYLDDTEATAAAIDADGWLHTGDIGAVDQAGNLRITDRLKDMYICGGFN 417 E+L+RG NVM+GYLDD E+TA IDADGWLHTGD+G +D G + ITDRLKDMYI GGFN Sbjct 365 EILVRGENVMLGYLDDPESTAKTIDADGWLHTGDVGTLDDRGYVDITDRLKDMYISGGFN 424 Query 418 VYPAEVEQVLARMDGVADAAVIGVPDQRLGEVGRAFVVARPGTGLDEASVIAYTREHLAN 477 VYPAEVE LAR+DGVA++AVIGVPDQR+GEVGRAFVVA+ GT L E VIA+ +E LA Sbjct 425 VYPAEVENALARLDGVAESAVIGVPDQRMGEVGRAFVVAKAGTALAEDDVIAFCKERLAG 484 Query 478 FKTPRSVRFVDVLPRNAAGKVSKPQLRE 505 FK PRSVRFVD LPRN +GKV K LRE Sbjct 485 FKVPRSVRFVDSLPRNPSGKVMKNVLRE 512 >gi|262203852|ref|YP_003275060.1| AMP-dependent synthetase and ligase [Gordonia bronchialis DSM 43247] gi|262087199|gb|ACY23167.1| AMP-dependent synthetase and ligase [Gordonia bronchialis DSM 43247] Length=523 Score = 561 bits (1446), Expect = 9e-158, Method: Compositional matrix adjust. Identities = 287/509 (57%), Positives = 360/509 (71%), Gaps = 11/509 (2%) Query 6 RTVPAALDRLVRQLPDHTALI----AEDRRFTSTELRDAVYGAAAALIALGVEPADRVAI 61 T PAAL R PD A++ ++ T T+L DAV G AA+L A G+ DRVA+ Sbjct 14 ETTPAALRRAAATWPDLPAIVDGQWSDPLELTWTQLHDAVRGFAASLAASGIGAGDRVAL 73 Query 62 WSPNTWHWVVACLAIHHAGAAVVPLNTRYTATEATDILDRAGAPVLFAAGLFLGADRAAG 121 WSPN++HW +A L +H+AGA +VPLNTRYTA EA +I+ R+ A + +G FLG D A Sbjct 74 WSPNSFHWPIAALGVHYAGATLVPLNTRYTAGEAIEIITRSKAKAVVVSGEFLGTDHLAD 133 Query 122 LDRAALPAL-RHVVRVPV-----EADDGTWDEFIATGAGA-LDAVAARAAAVAPQDVSDI 174 L R AL R +V VP+ A +W E +A L RA +V+P+D+SDI Sbjct 134 LLRDHADALPRVIVHVPLAPSASPAPAVSWGEVLARATDENLAEADRRADSVSPEDISDI 193 Query 175 LFTSGTTGRSKGVLCAHRQSLSASASWAANGKITSDDRYLCINPFFHNFGYKAGILACLQ 234 LFTSGTTG+SKGVL HRQ+++ S +W ANG++ +RYL +NP+FH FGYKAGIL C+ Sbjct 194 LFTSGTTGKSKGVLATHRQTVAGSHAWGANGRLHPGERYLMVNPYFHTFGYKAGILPCVL 253 Query 235 TGATLIPHVTFDPLHALRAIERHRITVLPGPPTIYQSLLDHPARKDFDLSSLRFAVTGAA 294 G T++P + P A+ R T+ PG PTI+Q++LD P R +FDLSSLR VTGAA Sbjct 254 FGVTMLPLAVYSPPAAMELAADQRATIFPGAPTIFQTILDAPDRAEFDLSSLRLVVTGAA 313 Query 295 TVPVVLVERMQSELDIDIVLTAYGLTEANGMGTMCRPEDDAVTVATTCGRPFADFELRIA 354 VPVVLVER+Q +L +D V+TAYGLTE +G + C P+DD TVA TCGR F E+R++ Sbjct 314 IVPVVLVERIQRDLGVDTVITAYGLTECSGFVSTCTPDDDDETVANTCGRAFDGMEIRLS 373 Query 355 DDGEVLLRGPNVMVGYLDDTEATAAAIDADGWLHTGDIGAVDQAGNLRITDRLKDMYICG 414 D+GEVL RG VM GYLDD +ATAA IDADGWLHTGDIG +D+ GNL+ITDRLKDMYICG Sbjct 374 DEGEVLARGKMVMAGYLDDPDATAATIDADGWLHTGDIGTLDEHGNLKITDRLKDMYICG 433 Query 415 GFNVYPAEVEQVLARMDGVADAAVIGVPDQRLGEVGRAFVVARPGTGLDEASVIAYTREH 474 GFNVYPAE+EQ LAR+DGV ++AV+GVPD+RLGEVGRA++ R G LDE VIAY REH Sbjct 434 GFNVYPAEIEQTLARLDGVTESAVVGVPDERLGEVGRAYLTLRDGADLDEERVIAYAREH 493 Query 475 LANFKTPRSVRFVDVLPRNAAGKVSKPQL 503 LANFK PRSV FV+ PRNAAGK+ K +L Sbjct 494 LANFKVPRSVVFVEAFPRNAAGKILKREL 522 >gi|226304379|ref|YP_002764337.1| fatty-acid--CoA ligase [Rhodococcus erythropolis PR4] gi|226183494|dbj|BAH31598.1| putative fatty-acid--CoA ligase [Rhodococcus erythropolis PR4] Length=513 Score = 561 bits (1446), Expect = 9e-158, Method: Compositional matrix adjust. Identities = 286/507 (57%), Positives = 359/507 (71%), Gaps = 9/507 (1%) Query 6 RTVPAALDRLVRQLPDHTALIAEDRRFTSTELRDAVYGAAAALIALGVEPADRVAIWSPN 65 RT+P+AL R + + A+ D R T +L V A ALI GV+ DRV IWSPN Sbjct 6 RTIPSALIRAAEEFGERAAIADGDTRLTFAQLHQRVRDFAGALINRGVKAGDRVVIWSPN 65 Query 66 TWHWVVACLAIHHAGAAVVPLNTRYTATEATDILDRAGAPVLFAAGLFLGADRAAGL-DR 124 T+HWV+A L +AGAA++P+NTRYT TEA DI++R A L G FL ADR L D Sbjct 66 TYHWVIALLGAQYAGAAIIPINTRYTGTEALDIIERVDAAALVVVGTFLKADRYQQLLDA 125 Query 125 AALPALRHVVRVPVEADDG-----TWDEFIATGAGALDAVA-ARAAAVAPQDVSDILFTS 178 ++ V++VP++ DD +++F+A A A ARAA V P DVSDILFTS Sbjct 126 NPDLSIPTVIQVPIDGDDDRDGVIEFEDFLALATDAARTEADARAAKVQPDDVSDILFTS 185 Query 179 GTTGRSKGVLCAHRQSLSASASWAANGKITSDDRYLCINPFFHNFGYKAGILACLQTGAT 238 GTTGRSKG + AHRQS++ + SW ++T+DD +L I+PFFH FGYKAGIL CL GAT Sbjct 186 GTTGRSKGAITAHRQSIAVAKSWGECAEVTTDDNFLIISPFFHTFGYKAGILVCLLNGAT 245 Query 239 LIPHVTFDPLHALRAIERHRITVLPGPPTIYQSLLDHPARKDFDLSSLRFAVTGAATVPV 298 ++P F+ L + +I++LPG PTIYQ++LDHP R ++DLSSLR A+TGAA VPV Sbjct 246 IVPVSVFNIDDTLALVNSEKISILPGAPTIYQTILDHPRRSEYDLSSLRIAITGAAPVPV 305 Query 299 VLVERMQSELDIDIVLTAYGLTEANGMGTMCRPEDDAVTVATTCGRPFADFELRIADDGE 358 LVERMQ+EL D VLTAYGLTEA + TMCR +DD VTV+T+ GR ADFE++I D GE Sbjct 306 ALVERMQAEL-FDAVLTAYGLTEAV-VATMCRTDDDPVTVSTSSGRATADFEVKIGDQGE 363 Query 359 VLLRGPNVMVGYLDDTEATAAAIDADGWLHTGDIGAVDQAGNLRITDRLKDMYICGGFNV 418 +LLRGPNVM+GYLDD E+TA AIDADGWLHTGD+G +D+ G L ITDRLKDMY+ GGFNV Sbjct 364 ILLRGPNVMLGYLDDPESTAKAIDADGWLHTGDVGTLDERGYLDITDRLKDMYVSGGFNV 423 Query 419 YPAEVEQVLARMDGVADAAVIGVPDQRLGEVGRAFVVARPGTGLDEASVIAYTREHLANF 478 YPAE+E +LAR+ GV ++A IG+PD R+GEVGR ++ G GL E SVIA+ +E +A F Sbjct 424 YPAEIEGMLARLPGVHESAAIGIPDHRMGEVGRVYIAQLDGAGLTEESVIAFLKEKIAGF 483 Query 479 KTPRSVRFVDVLPRNAAGKVSKPQLRE 505 K PR VRFVD LPRN +GKV K LRE Sbjct 484 KVPREVRFVDHLPRNPSGKVLKTVLRE 510 >gi|229494537|ref|ZP_04388300.1| putative fatty-acid-coa ligase fadd3 [Rhodococcus erythropolis SK121] gi|229318899|gb|EEN84757.1| putative fatty-acid-coa ligase fadd3 [Rhodococcus erythropolis SK121] Length=513 Score = 560 bits (1442), Expect = 3e-157, Method: Compositional matrix adjust. Identities = 287/508 (57%), Positives = 360/508 (71%), Gaps = 11/508 (2%) Query 6 RTVPAALDRLVRQLPDHTALIAEDRRFTSTELRDAVYGAAAALIALGVEPADRVAIWSPN 65 RT+P+AL R + + A+ D R T +L V A ALI GV+ DRV IW+PN Sbjct 6 RTIPSALIRAAEEFGERAAIADGDTRLTFAQLHQRVRDFAGALINRGVKAGDRVVIWAPN 65 Query 66 TWHWVVACLAIHHAGAAVVPLNTRYTATEATDILDRAGAPVLFAAGLFLGADRAAGLDRA 125 T+HWV+A L +AGAA++P+NTRYT TEA DI++R A L G FL ADR L A Sbjct 66 TYHWVIALLGAQYAGAAIIPINTRYTGTEALDIIERVDAAALVVVGTFLKADRYQQLLDA 125 Query 126 ALPALR--HVVRVPVEADDG-----TWDEFIATGAGALDAVA-ARAAAVAPQDVSDILFT 177 P LR V++VP++ DD +++F+A A A ARAA V P DVSDILFT Sbjct 126 N-PDLRIPTVIQVPIDGDDDRDGVIEFEDFLALATDAARTEADARAAKVQPDDVSDILFT 184 Query 178 SGTTGRSKGVLCAHRQSLSASASWAANGKITSDDRYLCINPFFHNFGYKAGILACLQTGA 237 SGTTGRSKG + AHRQS++ + SW ++T+DD +L I+PFFH FGYKAGIL CL GA Sbjct 185 SGTTGRSKGAITAHRQSIAVAKSWGECAEVTADDNFLIISPFFHTFGYKAGILVCLLNGA 244 Query 238 TLIPHVTFDPLHALRAIERHRITVLPGPPTIYQSLLDHPARKDFDLSSLRFAVTGAATVP 297 T++P F+ L + +I++LPG PTIYQ++LDHP R ++DLSSLR A+TGAA VP Sbjct 245 TIVPVSVFNIDDTLALVNSEKISILPGAPTIYQTILDHPRRSEYDLSSLRIAITGAAPVP 304 Query 298 VVLVERMQSELDIDIVLTAYGLTEANGMGTMCRPEDDAVTVATTCGRPFADFELRIADDG 357 V LVERMQ+EL D VLTAYGLTEA + TMCR +DD VTV+T+ GR ADFE++I + G Sbjct 305 VALVERMQAEL-FDAVLTAYGLTEAV-VATMCRTDDDPVTVSTSSGRATADFEVKIGEQG 362 Query 358 EVLLRGPNVMVGYLDDTEATAAAIDADGWLHTGDIGAVDQAGNLRITDRLKDMYICGGFN 417 E+LLRGPNVM+GYLDD E+TA AIDADGWLHTGD+G +D+ G L ITDRLKDMY+ GGFN Sbjct 363 EILLRGPNVMLGYLDDPESTAKAIDADGWLHTGDVGTLDERGYLDITDRLKDMYVSGGFN 422 Query 418 VYPAEVEQVLARMDGVADAAVIGVPDQRLGEVGRAFVVARPGTGLDEASVIAYTREHLAN 477 VYPAE+E +LAR+ GV ++A IG+PD R+GEVGR ++ G GL E SVIA+ +E +A Sbjct 423 VYPAEIEGMLARLPGVHESAAIGIPDHRMGEVGRVYIAQLDGAGLTEESVIAFLKEKIAG 482 Query 478 FKTPRSVRFVDVLPRNAAGKVSKPQLRE 505 FK PR VRFVD LPRN +GKV K LRE Sbjct 483 FKVPREVRFVDHLPRNPSGKVLKTVLRE 510 >gi|326384061|ref|ZP_08205744.1| long-chain-fatty-acid--CoA ligase [Gordonia neofelifaecis NRRL B-59395] gi|326197221|gb|EGD54412.1| long-chain-fatty-acid--CoA ligase [Gordonia neofelifaecis NRRL B-59395] Length=514 Score = 558 bits (1437), Expect = 1e-156, Method: Compositional matrix adjust. Identities = 279/507 (56%), Positives = 364/507 (72%), Gaps = 10/507 (1%) Query 7 TVPAALDRLVRQLPDHTALI----AEDRRFTSTELRDAVYGAAAALIALGVEPADRVAIW 62 T PAAL R Q PD A++ E T + D V AA LI LGV DRVA+W Sbjct 7 TTPAALHRAETQWPDGIAVVDDQWGEHIELTWPQFADRVREFAAGLIGLGVRHGDRVAVW 66 Query 63 SPNTWHWVVACLAIHHAGAAVVPLNTRYTATEATDILDRAGAPVLFAAGLFLGADRAAGL 122 +PN++HW +A + I +AGA ++PLNTRYTA+EATDI+DR+ A V+ +G F G +R A + Sbjct 67 APNSFHWPIAAVGIQYAGAVLIPLNTRYTASEATDIIDRSDAKVVVVSGEFAGINRLAEV 126 Query 123 DRAALPALRHVVRVPVE--AD-DGT--WDEFIATGAGAL-DAVAARAAAVAPQDVSDILF 176 +++P R VV VP++ AD DG W+ +A+ + L + RA AV D+SDILF Sbjct 127 LGSSIPEGRTVVSVPLDDAADADGVVGWNALMASASAELVEQARERAEAVREDDLSDILF 186 Query 177 TSGTTGRSKGVLCAHRQSLSASASWAANGKITSDDRYLCINPFFHNFGYKAGILACLQTG 236 TSGTTG KGV+ H+Q++ S +W NG++ + DRYL +NP+FH FGYKAGIL L G Sbjct 187 TSGTTGAPKGVMAEHQQTVHGSHAWGDNGRLRAGDRYLMVNPYFHTFGYKAGILPSLLFG 246 Query 237 ATLIPHVTFDPLHALRAIERHRITVLPGPPTIYQSLLDHPARKDFDLSSLRFAVTGAATV 296 AT++P + P +++ + R +ITV PG PTI+Q++LD P R ++DLSSLR VTGA V Sbjct 247 ATMLPLAVYSPSESMKMVAREKITVFPGAPTIFQTILDDPTRAEYDLSSLRLIVTGATIV 306 Query 297 PVVLVERMQSELDIDIVLTAYGLTEANGMGTMCRPEDDAVTVATTCGRPFADFELRIADD 356 PVVL+ER+QS+L ++ V+TAYG TE +G T CRP+DDAVTVATTCGR F E++++++ Sbjct 307 PVVLIERLQSDLGVEAVVTAYGQTETSGFITTCRPDDDAVTVATTCGRAFPGMEVKLSEE 366 Query 357 GEVLLRGPNVMVGYLDDTEATAAAIDADGWLHTGDIGAVDQAGNLRITDRLKDMYICGGF 416 GEVL RG VM GYLD+ ATA IDADGWLHTGDIG +D+ GNL ITDRLKDMYICGGF Sbjct 367 GEVLARGLMVMRGYLDNPRATAETIDADGWLHTGDIGTLDERGNLTITDRLKDMYICGGF 426 Query 417 NVYPAEVEQVLARMDGVADAAVIGVPDQRLGEVGRAFVVARPGTGLDEASVIAYTREHLA 476 NVYPAEVEQ+L+R V +AAVIGVPD+RLGEVG+AF+ RPG+ +D A+VIA+ REHLA Sbjct 427 NVYPAEVEQLLSRFPDVTEAAVIGVPDERLGEVGKAFLTVRPGSDVDAAAVIAFAREHLA 486 Query 477 NFKTPRSVRFVDVLPRNAAGKVSKPQL 503 NFK PR++ VD PRNAAGK+ K ++ Sbjct 487 NFKVPRAIEIVDAFPRNAAGKILKREM 513 >gi|333918615|ref|YP_004492196.1| CoA ligase [Amycolicicoccus subflavus DQS3-9A1] gi|333480836|gb|AEF39396.1| CoA ligase [Amycolicicoccus subflavus DQS3-9A1] Length=534 Score = 551 bits (1419), Expect = 1e-154, Method: Compositional matrix adjust. Identities = 295/521 (57%), Positives = 357/521 (69%), Gaps = 24/521 (4%) Query 7 TVPAALDRLVRQLPDHTALIAEDRRFTSTELRDAVYGAAAALIALGVEPADRVAIWSPNT 66 TVPAAL + PD A++ + R T EL ++V A IA + P DR+A+WSPNT Sbjct 9 TVPAALLATAEKHPDREAIVDGETRLTYRELLESVRRCAGFFIAQEIRPGDRIAVWSPNT 68 Query 67 WHWVVACLAIHHAGAAVVPLNTRYTATEATDILDRAGAPVLFAAGLFLGADRAAGLDRAA 126 HW+VA L AGA +VP+NTR+T EA DILDR A L AG FLG DR A L A Sbjct 69 HHWIVAALGALMAGATLVPINTRFTGGEALDILDRTRASALIVAGPFLGTDRLAQLRETA 128 Query 127 ------LPALRHVVRVPVE----ADDGT--WDEFIATGAGALDAVAARAAAVAPQDVSDI 174 LP L +VR+PV+ AD WD+ +G +++ RA + P+ + DI Sbjct 129 GDLARSLPKLHTIVRIPVDGPINADPSAVAWDDITDSGISP-ESIDERATTITPESLCDI 187 Query 175 LFTSGTTGRSKGVLCAHRQSLSASASWAANGKITSDDRYLCINPFFHNFGYKAGILACLQ 234 LFTSGTTGRSKG + +H QSL +ASWA G +T DDRYL INPFFH+FGYKAGIL L Sbjct 188 LFTSGTTGRSKGAMSSHAQSLGVAASWAEIGGVTYDDRYLIINPFFHSFGYKAGILVSLL 247 Query 235 TGATLIPHVTFDPLHALRAIERHRITVLPGPPTIYQSLLDHPARKDFDLSSLRFAVTGAA 294 TGA + P TFD A IE+ RITVLPG PTIYQ +L+HP R D DL+SLR AVTGAA Sbjct 248 TGAAMYPAATFDVERAFEHIEQERITVLPGAPTIYQMMLEHPQRGDHDLTSLRLAVTGAA 307 Query 295 TVPVVLVERMQSELDIDIVLTAYGLTEANGMGTMCRPEDDAVTVATTCGRPFADFELRIA 354 VPV LVERM+S+L +VLTAYGLTEA + TMCRPED A T+A TCGR A+FE+R+A Sbjct 308 IVPVTLVERMRSDLGFAVVLTAYGLTEAV-VATMCRPEDSAETIANTCGRAAAEFEVRVA 366 Query 355 ----------DDGEVLLRGPNVMVGYLDDTEATAAAIDADGWLHTGDIGAVDQAGNLRIT 404 + GEVLLRGPNVM+GYLDD +AT AAID +GWLHTGD G + G L+IT Sbjct 367 HPDGAGCAPGEQGEVLLRGPNVMLGYLDDPDATRAAIDENGWLHTGDAGVLSAEGYLKIT 426 Query 405 DRLKDMYICGGFNVYPAEVEQVLARMDGVADAAVIGVPDQRLGEVGRAFVVARPGTGLDE 464 DR+KDMY+ GGFNVYPAEVEQ LAR+ GVA++AVIGVPD+RLGEVGR +V G L E Sbjct 427 DRIKDMYVSGGFNVYPAEVEQCLARLPGVAESAVIGVPDERLGEVGRVYVRVEHGHSLIE 486 Query 465 ASVIAYTREHLANFKTPRSVRFVDVLPRNAAGKVSKPQLRE 505 +I + ++HLAN+K PR V+FVD LPRN AGKV K +LRE Sbjct 487 DDIITHAKQHLANYKIPRQVQFVDALPRNPAGKVLKRELRE 527 >gi|319947747|ref|ZP_08021953.1| AMP-dependent synthetase and ligase [Dietzia cinnamea P4] gi|319438597|gb|EFV93511.1| AMP-dependent synthetase and ligase [Dietzia cinnamea P4] Length=548 Score = 535 bits (1379), Expect = 5e-150, Method: Compositional matrix adjust. Identities = 285/534 (54%), Positives = 360/534 (68%), Gaps = 34/534 (6%) Query 5 LRTVPAALDRLVRQLPDHTALI----AEDRRFTSTELRDAVYGAAAALIALGVEPADRVA 60 + + PAAL R P+ A+ +D R+T ++L D V AA L+A GV P DRV Sbjct 15 VESTPAALRRAAETWPEREAIADVQPGQDTRWTWSQLLDEVRRFAAGLVARGVTPGDRVV 74 Query 61 IWSPNTWHWVVACLAIHHAGAAVVPLNTRYTATEATDILDRAGAPVLFAAGLFLGADRAA 120 IW+PNT HWVVA L + AGA +VP NTRYT +E +I+ R GA AG FLG++R A Sbjct 75 IWAPNTRHWVVAALGVQFAGATMVPANTRYTGSETLEIIQRTGAVAAVVAGAFLGSERIA 134 Query 121 GLDR---------------AALPALRHVVRVPVEADD------GT--------WDEFIAT 151 L A +LR +VR+P++A D GT +D+ A Sbjct 135 DLADAAGADGADGAADRPLAGATSLRTIVRIPLDAGDTVPAGAGTAGGVDVVDFDDLRAL 194 Query 152 GAGALDAVA-ARAAAVAPQDVSDILFTSGTTGRSKGVLCAHRQSLSASASWAANGKITSD 210 L A A ARA AV +DV+DILFTSGTTG+SKGV+ HRQ+++ S +W +N +T Sbjct 195 ATAELLAEADARADAVTGEDVADILFTSGTTGKSKGVVALHRQTVAGSRAWGSNNGLTDR 254 Query 211 DRYLCINPFFHNFGYKAGILACLQTGATLIPHVTFDPLHALRAIERHRITVLPGPPTIYQ 270 D YL +NPFFH+FGYKAG LAC+ G T++P + +R I+ ++TVL G PTI+Q Sbjct 255 DGYLIVNPFFHSFGYKAGFLACILFGVTIVPLSVYSTTETMRLIQSEKVTVLTGAPTIFQ 314 Query 271 SLLDHPARKDFDLSSLRFAVTGAATVPVVLVERMQSELDIDIVLTAYGLTEANGMGTMCR 330 +LLD PAR ++DLSSLR AVTGA+ VPVVLVERMQS+L ++ V+TAYG TE G T R Sbjct 315 TLLDDPARGEYDLSSLRVAVTGASVVPVVLVERMQSDLGLETVITAYGQTETMGFITTTR 374 Query 331 PEDDAVTVATTCGRPFADFELRIADDGEVLLRGPNVMVGYLDDTEATAAAIDADGWLHTG 390 DD VTV+TTCGR + E+RI + GE+L RG VM GYLDD E TA ID DGWLHTG Sbjct 375 TGDDDVTVSTTCGRAYPGMEIRIGEHGEILTRGEMVMQGYLDDPENTAKTIDPDGWLHTG 434 Query 391 DIGAVDQAGNLRITDRLKDMYICGGFNVYPAEVEQVLARMDGVADAAVIGVPDQRLGEVG 450 D+G +D AGNLRITDRLKDMYI GGFNVYPAE+EQ LAR+DGV ++AVIGVPD+R+GEVG Sbjct 435 DVGEIDAAGNLRITDRLKDMYINGGFNVYPAEIEQTLARLDGVVESAVIGVPDERMGEVG 494 Query 451 RAFVVARPGTGLDEASVIAYTREHLANFKTPRSVRFVDVLPRNAAGKVSKPQLR 504 +AF+V R G+ L E V+ + REHLANFK PRSV FV+ LPRNA+GK+ K +LR Sbjct 495 KAFLVRREGSDLTEQDVLDFCREHLANFKRPRSVEFVESLPRNASGKILKTELR 548 >gi|312138168|ref|YP_004005504.1| acyl-CoA ligase/synthetase [Rhodococcus equi 103S] gi|311887507|emb|CBH46819.1| putative acyl-CoA ligase/synthetase [Rhodococcus equi 103S] Length=525 Score = 529 bits (1362), Expect = 5e-148, Method: Compositional matrix adjust. Identities = 277/525 (53%), Positives = 357/525 (68%), Gaps = 23/525 (4%) Query 1 LINDLRTVPAALDRLVRQLPDHTALIAEDRRFTSTELRDAVYGAAAALIALGVEPADRVA 60 + + RT PAAL R V Q + A+ R T TEL + V AA AL+A GVE DRVA Sbjct 1 MTTEPRTTPAALWRAVEQFGSNEAVADGSDRTTYTELLERVRLAARALMAKGVEAGDRVA 60 Query 61 IWSPNTWHWVVACLAIHHAGAAVVPLNTRYTATEATDILDRAGAPVLFAAGLFLGADRAA 120 +W+PNT HW+ A LA +AGA +VP++TRYT EA D+L+R A VL FL DR A Sbjct 61 VWAPNTHHWIEAFLAAQYAGATLVPISTRYTGHEALDLLERTRAKVLVVPDRFLKNDRLA 120 Query 121 GLDRAA----LPALRHVVRVPVEADDGT---------------WDEFIATGAG-ALDAVA 160 + +AA +P+L+ V+R P +DD T WD+ A +++ Sbjct 121 DVLKAAGPGGIPSLQLVLRTP--SDDPTSGAPTTEFPGGEILEWDQLAAAAEPVSVEEAD 178 Query 161 ARAAAVAPQDVSDILFTSGTTGRSKGVLCAHRQSLSASASWAANGKITSDDRYLCINPFF 220 ARA AV+P DV+DILFTSGTTG+SKGV+ AHRQ++ + +WA ++ +DRYL INPFF Sbjct 179 ARARAVSPDDVADILFTSGTTGKSKGVMTAHRQTVGIADAWADCAEVDENDRYLVINPFF 238 Query 221 HNFGYKAGILACLQTGATLIPHVTFDPLHALRAIERHRITVLPGPPTIYQSLLDHPARKD 280 H FGYKAG++ C+ GAT++P FD + I +I+VLPG PTI+Q++LD P R + Sbjct 239 HTFGYKAGLMVCILRGATMVPAAVFDVPTIMTTIANEKISVLPGAPTIHQTILDFPTRDE 298 Query 281 FDLSSLRFAVTGAATVPVVLVERMQSELDIDIVLTAYGLTEANGMGTMCRPEDDAVTVAT 340 +DLSSLR A+TGAA +PVVLVERMQ+EL D V+TAYG TEA + TMCR +DD VTVAT Sbjct 299 YDLSSLRVAITGAAAIPVVLVERMQAELGYDAVITAYGQTEAVVV-TMCRTDDDPVTVAT 357 Query 341 TCGRPFADFELRIADDGEVLLRGPNVMVGYLDDTEATAAAIDADGWLHTGDIGAVDQAGN 400 + GR E++I + GE+L+RG NVM+GYLDD E+T IDADGWLHTGD+G +D+ G Sbjct 358 SSGRAIPGMEVKIGEHGEILVRGDNVMLGYLDDPESTKKTIDADGWLHTGDVGVLDERGY 417 Query 401 LRITDRLKDMYICGGFNVYPAEVEQVLARMDGVADAAVIGVPDQRLGEVGRAFVVARPGT 460 L ITDRLKDMYI GFNVYPAE+E LARMD + +AAVIG+PD+R GEVGRA++V + G Sbjct 418 LDITDRLKDMYISNGFNVYPAEIENALARMDSIVEAAVIGIPDERAGEVGRAYIVPKAGV 477 Query 461 GLDEASVIAYTREHLANFKTPRSVRFVDVLPRNAAGKVSKPQLRE 505 + VIA+ +E LANFK PR V+ V LPRN +GKV K LRE Sbjct 478 DVTAEDVIAFCKERLANFKIPREVKIVGALPRNPSGKVLKNDLRE 522 >gi|325674928|ref|ZP_08154615.1| CoA ligase [Rhodococcus equi ATCC 33707] gi|325554514|gb|EGD24189.1| CoA ligase [Rhodococcus equi ATCC 33707] Length=529 Score = 529 bits (1362), Expect = 5e-148, Method: Compositional matrix adjust. Identities = 277/520 (54%), Positives = 355/520 (69%), Gaps = 23/520 (4%) Query 6 RTVPAALDRLVRQLPDHTALIAEDRRFTSTELRDAVYGAAAALIALGVEPADRVAIWSPN 65 RT PAAL R V Q + A+ R T TEL + V AA AL+A GVE DRVA+W+PN Sbjct 10 RTTPAALWRAVEQFGSNEAVADGSDRTTYTELLERVRLAARALMAKGVEAGDRVAVWAPN 69 Query 66 TWHWVVACLAIHHAGAAVVPLNTRYTATEATDILDRAGAPVLFAAGLFLGADRAAGLDRA 125 T HW+ A LA +AGA +VP++TRYT EA D+L+R A VL FL DR A + +A Sbjct 70 THHWIEAFLAAQYAGATLVPISTRYTGHEALDLLERTRAKVLVVPDRFLKNDRLADVLKA 129 Query 126 A----LPALRHVVRVPVEADDGT---------------WDEFIATGAG-ALDAVAARAAA 165 A +P+L+ V+R P +DD T WD+ A +++ ARA A Sbjct 130 AGPGGIPSLQLVLRTP--SDDPTSGAPTTEFPGGEILEWDQLAAAAEPVSVEEADARARA 187 Query 166 VAPQDVSDILFTSGTTGRSKGVLCAHRQSLSASASWAANGKITSDDRYLCINPFFHNFGY 225 V+P DV+DILFTSGTTG+SKGV+ AHRQ++ + +WA ++ +DRYL INPFFH FGY Sbjct 188 VSPDDVADILFTSGTTGKSKGVMTAHRQTVGIADAWADCAEVDENDRYLVINPFFHTFGY 247 Query 226 KAGILACLQTGATLIPHVTFDPLHALRAIERHRITVLPGPPTIYQSLLDHPARKDFDLSS 285 KAG++ C+ GAT++P FD + I +I+VLPG PTI+Q++LD P R ++DLSS Sbjct 248 KAGLMVCILRGATMVPAAVFDVPTIMTTIANEKISVLPGAPTIHQTILDFPTRDEYDLSS 307 Query 286 LRFAVTGAATVPVVLVERMQSELDIDIVLTAYGLTEANGMGTMCRPEDDAVTVATTCGRP 345 LR A+TGAA +PVVLVERMQ+EL D V+TAYG TEA + TMCR +DD VTVAT+ GR Sbjct 308 LRVAITGAAAIPVVLVERMQAELGYDAVITAYGQTEAVVV-TMCRTDDDPVTVATSSGRA 366 Query 346 FADFELRIADDGEVLLRGPNVMVGYLDDTEATAAAIDADGWLHTGDIGAVDQAGNLRITD 405 E++I + GE+L+RG NVM+GYLDD E+T IDADGWLHTGD+G +D+ G L ITD Sbjct 367 IPGMEVKIGEHGEILVRGDNVMLGYLDDPESTKKTIDADGWLHTGDVGVLDERGYLDITD 426 Query 406 RLKDMYICGGFNVYPAEVEQVLARMDGVADAAVIGVPDQRLGEVGRAFVVARPGTGLDEA 465 RLKDMYI GFNVYPAE+E LARMD + +AAVIG+PD+R GEVGRA++V + G + Sbjct 427 RLKDMYISNGFNVYPAEIENALARMDSIVEAAVIGIPDERAGEVGRAYIVPKAGVDVTAE 486 Query 466 SVIAYTREHLANFKTPRSVRFVDVLPRNAAGKVSKPQLRE 505 VIA+ +E LANFK PR V+ V LPRN +GKV K LRE Sbjct 487 DVIAFCKERLANFKIPREVKIVGALPRNPSGKVLKNDLRE 526 >gi|300785282|ref|YP_003765573.1| acyl-CoA synthetase [Amycolatopsis mediterranei U32] gi|299794796|gb|ADJ45171.1| acyl-CoA synthetase [Amycolatopsis mediterranei U32] gi|340526725|gb|AEK41930.1| acyl-CoA synthetase [Amycolatopsis mediterranei S699] Length=510 Score = 517 bits (1332), Expect = 1e-144, Method: Compositional matrix adjust. Identities = 294/509 (58%), Positives = 354/509 (70%), Gaps = 16/509 (3%) Query 7 TVPAALDRLVRQLPDHTALIAEDRRFTSTELRDAVYGAAAALIALGVEPADRVAIWSPNT 66 T+PA + + AL+ R +L + V A A A GV+ DRVA+ PNT Sbjct 5 TIPAVVRDAAAKFGSAEALVDGSVRLGYDQLLERVQTVARAFAACGVQAGDRVAVALPNT 64 Query 67 WHWVVACLAIHHAGAAVVPLNTRYTATEATDILDRAGAPVLFAAGLFLGADRAAGLDR-- 124 HWV A L +AGAA++P+NTR+TATE D+L R A L A FLG DR A + Sbjct 65 HHWVFAALGALYAGAALIPVNTRFTATETVDLLVRGRAKALVVAADFLGTDRHAAIRETG 124 Query 125 AALPALRHVVRVPVEAD----DGT--WDEFIATGAGALDAVA-ARAAAVAPQDVSDILFT 177 AALP L VVRVP++ +GT WDEF+A A A ARA AV P +VSDILFT Sbjct 125 AALPDLATVVRVPLQKPHRPVEGTVGWDEFLAMAERVPPAEAEARADAVGPDEVSDILFT 184 Query 178 SGTTGRSKGVLCAHRQSLSASASWAANGKITSDDRYLCINPFFHNFGYKAGILACLQTGA 237 SGT+GRSKGVL AHRQ++ +A+WA G++T+DDRYL INPFFH+FGYKAGI+ L TGA Sbjct 185 SGTSGRSKGVLSAHRQTVEVAAAWADCGQVTADDRYLVINPFFHSFGYKAGIVVGLLTGA 244 Query 238 TLIPHVTFDPLHALRAIERHRITVLPGPPTIYQSLLDHPARKDFDLSSLRFAVTGAATVP 297 T++P FD AL+AIER RI+V+PG PT++QSLL P + DLSSLR AVTGAATVP Sbjct 245 TIVPQAVFDVRAALKAIERERISVVPGAPTVFQSLLHEP--RKGDLSSLRLAVTGAATVP 302 Query 298 VVLVERMQSELDIDIVLTAYGLTEANGMGTMCRPEDDAVTVATTCGRPFADFELRI-ADD 356 LV RM+SEL + +LTAYGLTEA + TMCRP D A VA+T GR A FE+ I Sbjct 303 ASLVRRMRSELGFETILTAYGLTEAV-VVTMCRPGDPAELVASTSGRATAGFEVAIEGSP 361 Query 357 GEVLLRGPNVMVGYLDDTEATAAAIDADGWLHTGDIGAVDQAGNLRITDRLKDMYICGGF 416 GE+++RGPNVM+GYLDD EATA A+D GWLHTGD+G +D AGNL IT RLKDMYICGGF Sbjct 362 GEIVVRGPNVMLGYLDDPEATAKAVDERGWLHTGDVGELDAAGNLTITGRLKDMYICGGF 421 Query 417 NVYPAEVEQVLARMDGVADAAVIGVPDQRLGEVGRAFVVARPGTGLDEASVIAYTREHLA 476 NVYPAEVE L + GV D AV+GVPD+RLGEVG+AFVV G GL E +VIA+ RE LA Sbjct 422 NVYPAEVEHALTELPGVRDVAVVGVPDERLGEVGKAFVV---GAGLTEEAVIAFCRERLA 478 Query 477 NFKTPRSVRFVDVLPRNAAGKVSKPQLRE 505 N+KTPR V F+D LPRNA+GKV K L E Sbjct 479 NYKTPRFVAFLDELPRNASGKVLKRLLTE 507 >gi|296141507|ref|YP_003648750.1| AMP-dependent synthetase and ligase [Tsukamurella paurometabola DSM 20162] gi|296029641|gb|ADG80411.1| AMP-dependent synthetase and ligase [Tsukamurella paurometabola DSM 20162] Length=510 Score = 517 bits (1332), Expect = 2e-144, Method: Compositional matrix adjust. Identities = 276/502 (55%), Positives = 343/502 (69%), Gaps = 11/502 (2%) Query 7 TVPAALDRLVRQLPDHTALIAEDRRFTSTELRDAVYGAAAALIALGVEPADRVAIWSPNT 66 T+ + L V + DH A++ D R + LRD A AL+A GV P DRVAI +PN Sbjct 4 TIASVLHTAVERFADHPAVVDGDLRISYASLRDRSRSVAKALLAEGVRPGDRVAICAPNG 63 Query 67 WHWVVACLAIHHAGAAVVPLNTRYTATEATDILDRAGAPVLFAAGLFLGADRAAGLDRAA 126 W+ A L + GA +VP+NTRYT E D+L+R A AG FLG DR + ++A Sbjct 64 HEWIEAALGLATIGAVLVPVNTRYTGPEIVDLLERTRARAFVVAGTFLGVDRLNLVHQSA 123 Query 127 --LPA-LRHVVRVPVEADDGTWDEFIATGAGALDA-VAARAAAVAPQDVSDILFTSGTTG 182 LP + V+R+P WD A G+G D + A V PQ SDI FTSGT+G Sbjct 124 GGLPENVATVLRLP------EWDSLAARGSGITDTELDVIGAEVTPQSPSDIFFTSGTSG 177 Query 183 RSKGVLCAHRQSLSASASWAANGKITSDDRYLCINPFFHNFGYKAGILACLQTGATLIPH 242 RSKG + H Q+L+ +A+WA +T DRYL ++PFFH FGYKAGILA LQ GAT+ P Sbjct 178 RSKGAVSTHAQTLANAANWAELVGVTDTDRYLILSPFFHIFGYKAGILAALQRGATMYPA 237 Query 243 VTFDPLHALRAIERHRITVLPGPPTIYQSLLDHPARKDFDLSSLRFAVTGAATVPVVLVE 302 TFD + A I R RI+VLPG PTI+Q +LDHP R+ +DLSSLR A TGAAT+PVVL+E Sbjct 238 QTFDVVQAFDLIHRERISVLPGVPTIHQMMLDHPDREKYDLSSLRAATTGAATIPVVLIE 297 Query 303 RMQSELDIDIVLTAYGLTEANGMGTMCRPEDDAVTVATTCGRPFADFELRIADDGEVLLR 362 RM+ EL D VLTAYGL+EA + TMCR +DD +ATT GR D ++RIADDGE+L+R Sbjct 298 RMRDELRYDRVLTAYGLSEAPVV-TMCRADDDPAVIATTSGRAVRDMQVRIADDGEILVR 356 Query 363 GPNVMVGYLDDTEATAAAIDADGWLHTGDIGAVDQAGNLRITDRLKDMYICGGFNVYPAE 422 GPNV+ Y +D +ATA A DADGW HTGD G++D+AGNLRITDR+KDM+ GGFNVYPAE Sbjct 357 GPNVIAEYFEDPDATARAFDADGWFHTGDAGSMDEAGNLRITDRIKDMFTNGGFNVYPAE 416 Query 423 VEQVLARMDGVADAAVIGVPDQRLGEVGRAFVVARPGTGLDEASVIAYTREHLANFKTPR 482 VEQV+AR++GVA++AV+GVP+ RLGEVG+AFVV L E +VIA+ RE LANFK PR Sbjct 417 VEQVIARIEGVAESAVVGVPEPRLGEVGKAFVVLTGSRELTEDAVIAHCRESLANFKVPR 476 Query 483 SVRFVDVLPRNAAGKVSKPQLR 504 SV FV LPRNA GKV K LR Sbjct 477 SVEFVSELPRNATGKVLKRVLR 498 >gi|159038431|ref|YP_001537684.1| AMP-dependent synthetase and ligase [Salinispora arenicola CNS-205] gi|157917266|gb|ABV98693.1| AMP-dependent synthetase and ligase [Salinispora arenicola CNS-205] Length=508 Score = 513 bits (1322), Expect = 2e-143, Method: Compositional matrix adjust. Identities = 288/501 (58%), Positives = 347/501 (70%), Gaps = 6/501 (1%) Query 7 TVPAALDRLVRQLPDHTALIAEDR-RFTSTELRDAVYGAAAALIALGVEPADRVAIWSPN 65 +VPAAL R R AL+ D + EL V A ALIA G+ P DR+A+W+PN Sbjct 4 SVPAALLRAARDFGTTPALVEPDVVHLSYEELLAEVRRVAQALIASGLRPGDRLALWAPN 63 Query 66 TWHWVVACLAIHHAGAAVVPLNTRYTATEATDILDRAGAPVLFAAGLFLGADRAAGLDRA 125 + WV+ L +AG +VP+NTR+T EA D++ R+GA L FLG DR A L A Sbjct 64 SAQWVLGALGGSYAGLTLVPVNTRFTGVEALDVIHRSGASGLVVVDPFLGTDRLATLQAA 123 Query 126 ALPALRHVVRVPVEADDGTWDEFIATGAGALDAVA-ARAAAVAPQDVSDILFTSGTTGRS 184 A R + RV V G WDEF++ + A A AAAV P D+SD+LFTSGTTGRS Sbjct 124 ATAEGRQLPRVIVRVPSG-WDEFVSQSRAVPELEADACAAAVTPDDLSDVLFTSGTTGRS 182 Query 185 KGVLCAHRQSLSASASWAANGKITSDDRYLCINPFFHNFGYKAGILACLQTGATLIPHVT 244 KGV+ AHRQS++ +A+WA ++T DDRYL INPFFH+FG KAGI ACL +G+ ++P Sbjct 183 KGVMSAHRQSMAVAAAWANIARLTPDDRYLVINPFFHSFGLKAGIFACLASGSAIVPQAV 242 Query 245 FDPLHALRAIERHRITVLPGPPTIYQSLLDHPARKDFDLSSLRFAVTGAATVPVVLVERM 304 FD + I RITVLPGPPT+Y SLL +P + FDLSSLR AVTGAATVP LVE++ Sbjct 243 FDVPRTMALIADQRITVLPGPPTLYTSLLGYPDARRFDLSSLRLAVTGAATVPPALVEQI 302 Query 305 QSELDIDIVLTAYGLTEANGMGTMCRPEDDAVTVATTCGRPFADFELRIAD-DGEVLLRG 363 + EL D VLTAYGLTEA + TMCRP DDA TVA TCGR A E+RIAD GEVLLRG Sbjct 303 RKELGAD-VLTAYGLTEAV-VATMCRPGDDARTVAETCGRAAAGCEVRIADPGGEVLLRG 360 Query 364 PNVMVGYLDDTEATAAAIDADGWLHTGDIGAVDQAGNLRITDRLKDMYICGGFNVYPAEV 423 PN M+GYLDD ATA AIDA+GWLHTGDIG +D+ G L ITDRLKDMY+CGGFNVYPAEV Sbjct 361 PNTMLGYLDDPIATAEAIDAEGWLHTGDIGQLDEHGYLTITDRLKDMYVCGGFNVYPAEV 420 Query 424 EQVLARMDGVADAAVIGVPDQRLGEVGRAFVVARPGTGLDEASVIAYTREHLANFKTPRS 483 E+ LA++ GVA++AVIGVPD RLG+VG+A+VV RPG L A VI + R LAN+K PRS Sbjct 421 ERALAQLPGVAESAVIGVPDPRLGDVGKAYVVCRPGHSLSAAEVIEFCRSRLANYKVPRS 480 Query 484 VRFVDVLPRNAAGKVSKPQLR 504 V LP NA+GKV K LR Sbjct 481 VEVRSELPHNASGKVLKYLLR 501 >gi|145595185|ref|YP_001159482.1| AMP-dependent synthetase and ligase [Salinispora tropica CNB-440] gi|145304522|gb|ABP55104.1| AMP-dependent synthetase and ligase [Salinispora tropica CNB-440] Length=510 Score = 509 bits (1310), Expect = 5e-142, Method: Compositional matrix adjust. Identities = 282/503 (57%), Positives = 345/503 (69%), Gaps = 6/503 (1%) Query 5 LRTVPAALDRLVRQLPDHTALIAED-RRFTSTELRDAVYGAAAALIALGVEPADRVAIWS 63 + ++PAAL R ++ AL+ + + EL V A ALIA G+ P DR+A+W+ Sbjct 2 MPSIPAALHRAAQEFSSAPALVEPGVTQLSYAELLAEVRRVAQALIAGGLRPGDRLALWA 61 Query 64 PNTWHWVVACLAIHHAGAAVVPLNTRYTATEATDILDRAGAPVLFAAGLFLGADRAAGLD 123 PN+ WV+A L +AG +VP+NTR+T EA D+ R+ A L FLG DR A L Sbjct 62 PNSAQWVLAALGASYAGLTLVPVNTRFTGIEALDVTHRSRASGLVVVDPFLGTDRLATLQ 121 Query 124 RAALPALRHVVRVPVEADDGTWDEFIATGAGALDAVAARAAAVAPQ-DVSDILFTSGTTG 182 AA + + R+ V G WDEF+A GA + VA AA D+SDILFTSGTTG Sbjct 122 AAATAEGKQLPRLVVRVPSG-WDEFVAGGASVPEPVANARAAAVNPNDLSDILFTSGTTG 180 Query 183 RSKGVLCAHRQSLSASASWAANGKITSDDRYLCINPFFHNFGYKAGILACLQTGATLIPH 242 RSKGV+ AHRQS+ + +WA ++T DDRYL INPFFH+FG KAGILAC+ +G ++P Sbjct 181 RSKGVMSAHRQSIDVATAWADIARLTPDDRYLVINPFFHSFGLKAGILACVVSGTAIVPQ 240 Query 243 VTFDPLHALRAIERHRITVLPGPPTIYQSLLDHPARKDFDLSSLRFAVTGAATVPVVLVE 302 FD A+ I RITVLPGPPT+Y SLL HP + FDLSSLR AVTGAATVP LV+ Sbjct 241 AVFDVPQAMALIADQRITVLPGPPTLYTSLLGHPDARRFDLSSLRLAVTGAATVPPALVD 300 Query 303 RMQSELDIDIVLTAYGLTEANGMGTMCRPEDDAVTVATTCGRPFADFELRIAD-DGEVLL 361 +++ EL D VLTAYGLTEA + TMCRP DDA TVA TCGR A E+RIAD GEVLL Sbjct 301 QIRKELGAD-VLTAYGLTEAV-VATMCRPGDDAQTVAQTCGRAAAGCEIRIADPGGEVLL 358 Query 362 RGPNVMVGYLDDTEATAAAIDADGWLHTGDIGAVDQAGNLRITDRLKDMYICGGFNVYPA 421 RGPN M+GYLDD ATAAAIDA+GWLHTGDIG +D+ G L ITDRLKDMY+CGGFNVYPA Sbjct 359 RGPNTMLGYLDDPTATAAAIDAEGWLHTGDIGRLDERGYLTITDRLKDMYVCGGFNVYPA 418 Query 422 EVEQVLARMDGVADAAVIGVPDQRLGEVGRAFVVARPGTGLDEASVIAYTREHLANFKTP 481 EVE+ LA++ GVA++AVIGVPD RLGEVG+A++V PG L A V + R LAN+K P Sbjct 419 EVERTLAQLPGVAESAVIGVPDPRLGEVGKAYLVCHPGHALSTAEVTEFCRSRLANYKVP 478 Query 482 RSVRFVDVLPRNAAGKVSKPQLR 504 RSV LP NA+GK+ K LR Sbjct 479 RSVEVRSELPHNASGKILKYLLR 501 >gi|337766351|emb|CCB75062.1| Acyl-CoA synthetase [Streptomyces cattleya NRRL 8057] Length=529 Score = 507 bits (1305), Expect = 2e-141, Method: Compositional matrix adjust. Identities = 281/526 (54%), Positives = 340/526 (65%), Gaps = 28/526 (5%) Query 4 DLRTVPAALDRLVRQLPDHTALIAEDRRFTSTELRDAVYGAAAALIALGVEPADRVAIWS 63 + ++PA + + R+ + A++ R T +L V AAAA +A GVEP DRVA+W+ Sbjct 6 EFGSIPALVTQAARRYGEREAVVEGRTRLTFAQLAKGVARAAAACLAHGVEPGDRVAVWA 65 Query 64 PNTWHWVVACLAIHHAGAAVVPLNTRYTATEATDILDRAGAPVLFAAGLFLGADRAAGLD 123 PNT WVVA L AG +VPLNTR+ EA +L R A +LF G FLG A L Sbjct 66 PNTADWVVAALGALSAGGVLVPLNTRFKGAEAAYVLRRTRARLLFVTGTFLGTSYVAALR 125 Query 124 RAA-------------------LPALRHVVRVPVEADDG-----TWDEFIATGAGALDA- 158 RAA LP LR VV V ADD TW +F+A G G DA Sbjct 126 RAAGGTNGSGGPGPVPTGPLPGLPYLRDVV---VLADDAPADFRTWPQFLAAGDGVGDAA 182 Query 159 VAARAAAVAPQDVSDILFTSGTTGRSKGVLCAHRQSLSASASWAANGKITSDDRYLCINP 218 V R + P D SDI+FTSGTTG KG + +H Q+L W+ +T DRYL +NP Sbjct 183 VRRRIGEIRPGDPSDIIFTSGTTGHPKGAVVSHAQTLRVYGVWSRLAGLTEGDRYLVVNP 242 Query 219 FFHNFGYKAGILACLQTGATLIPHVTFDPLHALRAIERHRITVLPGPPTIYQSLLDHPAR 278 FFH FGYKAGI+ACL GAT++P FDP L + ITVLPGPPT+ SLLDHP R Sbjct 243 FFHTFGYKAGIVACLLRGATIVPQPVFDPAVVLANLAAEHITVLPGPPTVLTSLLDHPDR 302 Query 279 KDFDLSSLRFAVTGAATVPVVLVERMQSELDIDIVLTAYGLTEANGMGTMCRPEDDAVTV 338 DLS+LR VTGAA VP+ LVER++ EL + VLTAYGLTEA G +MCRP D V Sbjct 303 GAHDLSALRVVVTGAAVVPLELVERLRGELGVATVLTAYGLTEATGTVSMCRPTDPPEVV 362 Query 339 ATTCGRPFADFELRIADDGEVLLRGPNVMVGYLDDTEATAAAIDADGWLHTGDIGAVDQA 398 A TCGRP E+RIA DGEVL+RG +VM GY +D ATA A+D DGWLHTGDIG++D+A Sbjct 363 AATCGRPLPGTEVRIAADGEVLVRGYHVMSGYFEDPVATAGAVDPDGWLHTGDIGSLDEA 422 Query 399 GNLRITDRLKDMYICGGFNVYPAEVEQVLARMDGVADAAVIGVPDQRLGEVGRAFVVARP 458 GNLRITDR+KDM+I GGFN YPAE+E+VL R VADAAVIGVPD RLGEVG+AFVV RP Sbjct 423 GNLRITDRVKDMFIVGGFNAYPAEIERVLRRHPDVADAAVIGVPDPRLGEVGKAFVVRRP 482 Query 459 GTGLDEASVIAYTREHLANFKTPRSVRFVDVLPRNAAGKVSKPQLR 504 T L ++I+++R +ANFK PR+V FV LPRNA+GKV K LR Sbjct 483 DTALTADALISWSRREMANFKVPRAVEFVAELPRNASGKVLKRALR 528 >gi|328883144|emb|CCA56383.1| Long-chain-fatty-acid--CoA ligase [Streptomyces venezuelae ATCC 10712] Length=521 Score = 499 bits (1286), Expect = 3e-139, Method: Compositional matrix adjust. Identities = 276/503 (55%), Positives = 336/503 (67%), Gaps = 5/503 (0%) Query 7 TVPAALDRLVRQLPDHTALIAEDRRFTSTELRDAVYGAAAALIALGVEPADRVAIWSPNT 66 T+P + + A++ R T TEL + V AAAA +A+GV DRVAIW+PNT Sbjct 11 TIPGLVRAAAERHGPREAVVDGRTRVTYTELGERVERAAAACLAIGVRAGDRVAIWAPNT 70 Query 67 WHWVVACLAIHHAGAAVVPLNTRYTATEATDILDRAGAPVLFAAGLFLGADRAAGLDRAA 126 W+VA L AGA +VPLNTR+ TEA +L R+ A +LF G FLG A L RA Sbjct 71 LDWIVAALGAVTAGAVLVPLNTRFKGTEAAFVLQRSRARLLFVTGTFLGTSYVASLRRAG 130 Query 127 --LPALRHVVRVPVEADD--GTWDEFIATG-AGALDAVAARAAAVAPQDVSDILFTSGTT 181 LP L VV + A + TW EF+A G A V ARA A+ P SDI++TSGTT Sbjct 131 VDLPDLEKVVVLGDTAPEEWTTWKEFLAEGDAVPAARVRARADAIDPTSPSDIIYTSGTT 190 Query 182 GRSKGVLCAHRQSLSASASWAANGKITSDDRYLCINPFFHNFGYKAGILACLQTGATLIP 241 GR KG + +H QSL A W + DRYL +NPFFH FGYKAGILACL GA ++P Sbjct 191 GRPKGAVISHAQSLRCYAIWCELAGLREGDRYLVVNPFFHTFGYKAGILACLMRGAVIVP 250 Query 242 HVTFDPLHALRAIERHRITVLPGPPTIYQSLLDHPARKDFDLSSLRFAVTGAATVPVVLV 301 F L I RITVLPGPPT++QSLLDHPAR L++LR VTGAA VP+ LV Sbjct 251 QSVFTVDTVLANIAAERITVLPGPPTLHQSLLDHPARGAHSLATLRLVVTGAAVVPLRLV 310 Query 302 ERMQSELDIDIVLTAYGLTEANGMGTMCRPEDDAVTVATTCGRPFADFELRIADDGEVLL 361 ER+++EL + VLTAYGL+EA+G+ TMCR ED A TVATT GR E+R++ GEVL+ Sbjct 311 ERLRTELGVGTVLTAYGLSEASGIVTMCRREDPAGTVATTSGRAIPGTEVRLSATGEVLV 370 Query 362 RGPNVMVGYLDDTEATAAAIDADGWLHTGDIGAVDQAGNLRITDRLKDMYICGGFNVYPA 421 RG +VM GY +D E TAAAIDADGWLHTGDIG +D+AGNLRITDRLKDM+I GGFN YPA Sbjct 371 RGHHVMSGYFEDPEETAAAIDADGWLHTGDIGVLDEAGNLRITDRLKDMFIVGGFNAYPA 430 Query 422 EVEQVLARMDGVADAAVIGVPDQRLGEVGRAFVVARPGTGLDEASVIAYTREHLANFKTP 481 E+EQ+L +AD AVIGVPD RLGEVG+AFVV RPG +IA++R +AN+K P Sbjct 431 EIEQLLGLHPDIADVAVIGVPDPRLGEVGKAFVVRRPGARATADDLIAWSRREMANYKVP 490 Query 482 RSVRFVDVLPRNAAGKVSKPQLR 504 R + FV LPRNA+GKV K +LR Sbjct 491 RQIEFVPDLPRNASGKVVKGELR 513 >gi|284043819|ref|YP_003394159.1| AMP-dependent synthetase and ligase [Conexibacter woesei DSM 14684] gi|283948040|gb|ADB50784.1| AMP-dependent synthetase and ligase [Conexibacter woesei DSM 14684] Length=552 Score = 499 bits (1284), Expect = 6e-139, Method: Compositional matrix adjust. Identities = 291/534 (55%), Positives = 346/534 (65%), Gaps = 37/534 (6%) Query 7 TVPAALDRLVRQLPDHTALIAEDRRFTSTELRDAVYGAAAALIALGVEPADRVAIWSPNT 66 T+P + Q H AL+ D R T L DAV A ALIA GV DRV +WSPNT Sbjct 13 TIPGLVKAAAEQFGAHEALVDGDVRMTFAALHDAVRDVARALIATGVRRGDRVCVWSPNT 72 Query 67 WHWVVACLAIHHAGAAVVPLNTRYTATEATDILDRAGAPVLFAAGLFLGADRAAGLDRA- 125 HWVVA LA H AGAA+VPLNTRYT EA DIL R+ VLF FLG D A L A Sbjct 73 HHWVVAALAAHSAGAALVPLNTRYTGAEAIDILGRSRVRVLFLPDTFLGRDYLASLREAE 132 Query 126 ------------------ALPALRHVVRVPVEADDGT------WDEFIATGAGALDAVA- 160 ALP L VVR+PVE + + W E + A A Sbjct 133 ATGAGGEPAEAGGGIPVPALPDLELVVRIPVEHERPSEPGVVAWSELVERAASTTAQEAD 192 Query 161 ARAAAVAPQDVSDILFTSGTTGRSKGVLCAHRQSLSASASWAANGKITSDDRYLCINPFF 220 ARAA V P DV+DILFTSGTTGR KG + +HRQ++ A+ +WA +++ DRY+ I PFF Sbjct 193 ARAAEVLPDDVADILFTSGTTGRPKGAMSSHRQAVEAAVAWAEPTEVSPADRYMIIAPFF 252 Query 221 HNFGYKAGILACLQTGATLIPHVTFDPLHALRAIERHRITVLPGPPTIYQSLLDHPARKD 280 H+FGYKAG+L L GAT++P +TFD AL AIER RIT+LPGPPTI+++LL HP R Sbjct 253 HSFGYKAGLLVGLLRGATIVPQITFDVDAALDAIERERITILPGPPTIFETLLAHPGRAG 312 Query 281 FDLSSLRFAVTGAATVPVVLVERMQSELDIDIVLTAYGLTEANGMGTMCRPEDDAVTVAT 340 DLSSLR AV G+A VPV LVERM+ EL VLT YGLTEA + TMCR +DD TV+ Sbjct 313 RDLSSLRLAVAGSAMVPVALVERMRRELTFQTVLTGYGLTEAV-VVTMCRADDDPQTVSG 371 Query 341 TCGRPFADFELRIA----------DDGEVLLRGPNVMVGYLDDTEATAAAIDADGWLHTG 390 + G A FELRIA + GE+ RGPNVM+GYLDD AT AIDADGW H+G Sbjct 372 SSGCATAGFELRIAGADGSALPPGEQGEIWFRGPNVMLGYLDDERATREAIDADGWFHSG 431 Query 391 DIGAVDQAGNLRITDRLKDMYICGGFNVYPAEVEQVLARMDGVADAAVIGVPDQRLGEVG 450 D+G +D G L ITDR+KDM GGFNVYPAEVE VLAR+DGV AAVIGVPD+R+GEV Sbjct 432 DVGRLDVRGYLTITDRIKDMLTVGGFNVYPAEVENVLARLDGVIAAAVIGVPDERMGEVP 491 Query 451 RAFVVARPGTGLDEASVIAYTREHLANFKTPRSVRFVDVLPRNAAGKVSKPQLR 504 A++VA+ LDE +V+A+ R LANFK PR+V FV+ LPRNAAGKV K +LR Sbjct 492 AAYLVAQEDHALDEGAVVAFCRRQLANFKVPRTVTFVEALPRNAAGKVLKSELR 545 >gi|119716992|ref|YP_923957.1| AMP-dependent synthetase and ligase [Nocardioides sp. JS614] gi|119537653|gb|ABL82270.1| AMP-dependent synthetase and ligase [Nocardioides sp. JS614] Length=489 Score = 496 bits (1278), Expect = 3e-138, Method: Compositional matrix adjust. Identities = 278/503 (56%), Positives = 339/503 (68%), Gaps = 24/503 (4%) Query 7 TVPAALDRLVRQLPDHTALIAEDRRFTSTELRDAVYGAAAALIALGVEPADRVAIWSPNT 66 T+P L + DH A + + T+L V AA A G+ P DRV +W+PN+ Sbjct 4 TIPGVLRAAAERFGDHPAYVEGGVTTSFTDLLGRVRRTAAGYRARGLSPGDRVVVWAPNS 63 Query 67 WHWVVACLAIHHAGAAVVPLNTRYTATEATDILDRAGAPVLFAAGLFLGADRAAGLDRA- 125 WVVA LA+ +AG +VP N+RYT E D++DR GA ++ A FLG + A L A Sbjct 64 VDWVVAALAVSYAGGTLVPANSRYTGHEVADLVDRTGAVLVVVADGFLGRTQVADLRAAG 123 Query 126 ALPALRHVVRV----PVEADDGTWDEFIATGAGALDAVAARAAAVAPQDVSDILFTSGTT 181 ALP +R V+ + VEA+ G DE AAAV+P DV+DILFTSGTT Sbjct 124 ALPGVREVIDLARIAEVEAEPGVIDEV--------------AAAVSPDDVADILFTSGTT 169 Query 182 GRSKGVLCAHRQSLSASASWAANGKITSDDRYLCINPFFHNFGYKAGILACLQTGATLIP 241 GR KG + AHRQ++ + +W + G ++++DRYL +NPFFH+FGYK GI+ L TGATL P Sbjct 170 GRPKGAMSAHRQTVGVARAWGSLGGVSTEDRYLVVNPFFHSFGYKVGIVTGLITGATLYP 229 Query 242 HVTFDPLHALRAIERHRITVLPGPPTIYQSLLDHPARKDFDLSSLRFAVTGAATVPVVLV 301 TFD +R IE RITVLPG PTIYQSLL P R DLSSLR AVTGAA VPVVL+ Sbjct 230 LATFDLDETMRLIETERITVLPGAPTIYQSLLSAPGRAGRDLSSLRLAVTGAAVVPVVLI 289 Query 302 ERMQSELDIDIVLTAYGLTEANGMGTMCRPEDDAVTVATTCGRPFADFELRIADDGEVLL 361 ERM+ EL ID V+TA+G+TEA + TMCR D A TVATTCGR E RI GE+L+ Sbjct 290 ERMREELGIDHVVTAFGMTEAV-VVTMCRDGDSAETVATTCGRAIPGMETRIGARGELLV 348 Query 362 RGPNVMVGYLDDTEATAAAIDADGWLHTGDIGAVDQAGNLRITDRLKDMYICGGFNVYPA 421 RG VM+GYLDD ATA AIDA+GWLHTGD+G +D+ GNL ITDRLKDMYICGGFNVYPA Sbjct 349 RGEFVMLGYLDDPAATAEAIDAEGWLHTGDVGVLDEHGNLSITDRLKDMYICGGFNVYPA 408 Query 422 EVEQVLARMDGVADAAVIGVPDQRLGEVGRAFVVARPGTGLDEASVIAYTREHLANFKTP 481 EVEQ LARMDGVAD AV+GVPD+RLGEVG+A+VV + V+A+ +E LANFK P Sbjct 409 EVEQALARMDGVADVAVVGVPDERLGEVGKAYVVG----AVTPDEVLAFAKERLANFKVP 464 Query 482 RSVRFVDVLPRNAAGKVSKPQLR 504 RSV D LPRN +GKV K +LR Sbjct 465 RSVEVTDALPRNLSGKVLKNELR 487 >gi|29830349|ref|NP_824983.1| long-chain-fatty-acid--CoA ligase [Streptomyces avermitilis MA-4680] gi|29607460|dbj|BAC71518.1| putative acyl-CoA synthetase, fatty acid:CoA ligase [Streptomyces avermitilis MA-4680] Length=527 Score = 488 bits (1257), Expect = 8e-136, Method: Compositional matrix adjust. Identities = 264/517 (52%), Positives = 334/517 (65%), Gaps = 19/517 (3%) Query 7 TVPAALDRLVRQLPDHTALIAEDRRFTSTELRDAVYGAAAALIALGVEPADRVAIWSPNT 66 ++P + + D A++ R + EL V AAAA IA GV DRV IW+PN+ Sbjct 9 SIPGLVRSSAERYADTEAVVEGRTRISYAELGARVERAAAACIASGVGVGDRVGIWAPNS 68 Query 67 WHWVVACLAIHHAGAAVVPLNTRYTATEATDILDRAGAPVLFAAGLFLGADRAAGLDRAA 126 W+V+ L AGA +VPLNTR+ +EA +L R+GA +LF G FLG A L RAA Sbjct 69 LDWIVSALGAVSAGAVLVPLNTRFKGSEAAYVLRRSGARLLFVTGTFLGTSYVASLRRAA 128 Query 127 ---------LPALRHVVRVPVEADDG-----TWDEFIATGAGALDA-VAARAAAVAPQDV 171 LP L + +V V ADD TW +F+A+G G +A RA + V Sbjct 129 GEGEGLRGPLPGLPALEQVVVLADDAPADFRTWKDFLASGEGVGEAETRERARGLDGSTV 188 Query 172 SDILFTSGTTGRSKGVLCAHRQSLSASASWAANGKITSDDRYLCINPFFHNFGYKAGILA 231 SDI+FTSGTTGR KG + H Q+L A W+ + DRYL NPFFH FGYKAG++A Sbjct 189 SDIIFTSGTTGRPKGAVITHAQTLRAYEVWSDLAGLRRGDRYLIANPFFHTFGYKAGVIA 248 Query 232 CLQTGATLIPHVTFDPLHALRAIERHRITVLPGPPTIYQSLLDHPARKDFDLSSLRFAVT 291 CL GAT+IP F+ L I R++VLPGPPT++QSLLDHPAR +DLS+LR VT Sbjct 249 CLMRGATMIPQPVFNVDTVLANIAAERVSVLPGPPTLHQSLLDHPARDAYDLSALRLVVT 308 Query 292 GAATVPVVLVERMQSELDIDIVLTAYGLTEANGMGTMCRPEDDAVTVATTCGRPFADFEL 351 GAA VP+ LVER++ EL + VLTAYGL+EA+G+ TMCR DD +A+T GR E+ Sbjct 309 GAAVVPLRLVERLRGELGVGTVLTAYGLSEASGIVTMCRRGDDPSVIASTSGRAIPGTEV 368 Query 352 RI----ADDGEVLLRGPNVMVGYLDDTEATAAAIDADGWLHTGDIGAVDQAGNLRITDRL 407 R+ GEVL+RG NVM GY +D ATAAA+ DGWL TGD+G +D +GNLRITDR+ Sbjct 369 RVEAPLGSPGEVLVRGFNVMRGYFEDERATAAALTEDGWLRTGDVGVLDASGNLRITDRI 428 Query 408 KDMYICGGFNVYPAEVEQVLARMDGVADAAVIGVPDQRLGEVGRAFVVARPGTGLDEASV 467 KDM+I GGFN YPAE+EQ+L VAD AVIGVPD RLGEVG+A+VV RPG+ L + Sbjct 429 KDMFIVGGFNAYPAEIEQLLGLHPDVADVAVIGVPDARLGEVGKAYVVRRPGSVLTGDDL 488 Query 468 IAYTREHLANFKTPRSVRFVDVLPRNAAGKVSKPQLR 504 IA++R +AN+K PR+V FV LPRNA GKV K +LR Sbjct 489 IAWSRREMANYKVPRAVEFVGELPRNAGGKVVKGELR 525 >gi|302552183|ref|ZP_07304525.1| O-succinylbenzoate-CoA ligase [Streptomyces viridochromogenes DSM 40736] gi|302469801|gb|EFL32894.1| O-succinylbenzoate-CoA ligase [Streptomyces viridochromogenes DSM 40736] Length=546 Score = 488 bits (1256), Expect = 1e-135, Method: Compositional matrix adjust. Identities = 268/524 (52%), Positives = 330/524 (63%), Gaps = 25/524 (4%) Query 7 TVPAALDRLVRQLPDHTALIAEDRRFTSTELRDAVYGAAAALIALGVEPADRVAIWSPNT 66 ++P + ++ D A++ R T EL V AAAA +A GVEP DRV +W+PNT Sbjct 9 SIPGLVRSAAQRYADVEAVVEGRTRITYAELGARVERAAAACLANGVEPGDRVGVWAPNT 68 Query 67 WHWVVACLAIHHAGAAVVPLNTRYTATEATDILDRAGAPVLFAAGLFLGADRAAGLDRAA 126 W+VA L AGA +VPLNTR+ TEA D+L R+G +LF G FLG A L RAA Sbjct 69 LDWIVAALGAVSAGAVLVPLNTRFKGTEAADVLRRSGTRLLFVTGTFLGTSYVASLRRAA 128 Query 127 --------LPALRHVVRVPVEADDG-----TWDEFIATGAGALDAVAARAAAVAPQD-VS 172 LP L + RV V A+D TW +F+A G G A A S Sbjct 129 GEGPGTGPLPGLPELERVVVLAEDAPADFLTWKDFLAGGEGVGPAAVRARADAVEGPWTS 188 Query 173 DILFTSGTTGRSKGVLCAHRQSLSASASWAANGKITSDDRYLCINPFFHNFGYKAGILAC 232 DI+FTSGTTGR KG + H QSL A W+ +T DRYL +NPFFH FGYKAG+LAC Sbjct 189 DIIFTSGTTGRPKGAVVTHAQSLRAYGIWSDLAGLTRGDRYLIVNPFFHTFGYKAGVLAC 248 Query 233 LQTGATLIPHVTFDPLHALRAIERHRITVLPGPPTIYQSLLDHPARKDFDLSSLRFAVTG 292 L GAT+IP F+ AL + R++VLPGPPT+ QSLLDHPAR DLS+LR VTG Sbjct 249 LMRGATMIPQPVFNVHTALANLAAERVSVLPGPPTLLQSLLDHPARDAHDLSALRLVVTG 308 Query 293 AATVPVVLVERMQSELDIDIVLTAYGLTEANGMGTMCRPEDDAVTVATTCGRPFADFELR 352 AA VP+ LVER++ EL + VLTAYGL+EA G+ TMCR DD +A+T GR E+R Sbjct 309 AAVVPLRLVERLREELGVGTVLTAYGLSEAGGVVTMCRRGDDPTVIASTSGRAIPGTEVR 368 Query 353 IAD-----------DGEVLLRGPNVMVGYLDDTEATAAAIDADGWLHTGDIGAVDQAGNL 401 + D GEVL+RG NVM GY +D ATA + DGWL TGD+G +D GNL Sbjct 369 VVDAEGRPLEPGTGAGEVLVRGFNVMSGYYEDAHATAEVLTPDGWLRTGDVGVLDPEGNL 428 Query 402 RITDRLKDMYICGGFNVYPAEVEQVLARMDGVADAAVIGVPDQRLGEVGRAFVVARPGTG 461 RITDRLKDM+I GGFN YPAE+EQ+L V+D AVIGVPD RLGEVG+A+VV RPG Sbjct 429 RITDRLKDMFIVGGFNAYPAEIEQLLGLHPDVSDVAVIGVPDARLGEVGKAYVVRRPGAL 488 Query 462 LDEASVIAYTREHLANFKTPRSVRFVDVLPRNAAGKVSKPQLRE 505 L +IA++R +AN+K PR+V FV LPRNA+GKV K LR+ Sbjct 489 LTSDDLIAWSRREMANYKVPRTVEFVAELPRNASGKVVKGALRD 532 >gi|326777403|ref|ZP_08236668.1| Long-chain-fatty-acid--CoA ligase [Streptomyces cf. griseus XylebKG-1] gi|326657736|gb|EGE42582.1| Long-chain-fatty-acid--CoA ligase [Streptomyces griseus XylebKG-1] Length=519 Score = 488 bits (1255), Expect = 1e-135, Method: Compositional matrix adjust. Identities = 265/483 (55%), Positives = 326/483 (68%), Gaps = 9/483 (1%) Query 31 RFTSTELRDAVYGAAAALIALGVEPADRVAIWSPNTWHWVVACLAIHHAGAAVVPLNTRY 90 R + TEL + V AAAA +A GVEP DRVAIW+PNT W+V+ L AGA +VPLNTR+ Sbjct 34 RLSYTELGERVERAAAACLASGVEPGDRVAIWAPNTPDWIVSALGAVTAGAVLVPLNTRF 93 Query 91 TATEATDILDRAGAPVLFAAGLFLGADRAAGLDRAA--LPALRHVVRVPVEA--DDGTWD 146 TEA +L R+ A +LF G FLG A L RA LP L VV + A D +W Sbjct 94 KGTEAAYVLRRSRARLLFVTGTFLGTSYVASLRRAEVRLPDLERVVVLADTAPEDYTSWP 153 Query 147 EFIATGAGAL-DAVAARAAAVAPQDVSDILFTSGTTGRSKGVLCAHRQSLSASASWAANG 205 +F+A G G L AV RAAA+AP D SDI++TSGTTG KG + H Q+L A W+ Sbjct 154 DFLAAGEGVLPSAVRERAAAIAPSDPSDIIYTSGTTGAPKGAVITHAQTLRAYGIWSDLA 213 Query 206 KITSDDRYLCINPFFHNFGYKAGILACLQTGATLIPHVTFDPLHALRAIERHRITVLPGP 265 + DRYL +NPFFH FGYKAGI+ACL GAT++P F+ L I RI+VLPGP Sbjct 214 GLREGDRYLIVNPFFHTFGYKAGIIACLMRGATMVPQPVFNVDTVLANIAAERISVLPGP 273 Query 266 PTIYQSLLDHPARKDFDLSSLRFAVTGAATVPVVLVERMQSELDIDIVLTAYGLTEANGM 325 PT++QSLLDHPAR DLS+LR VTGAA VP+ LVER+++EL I VLTAYGL+EA+G+ Sbjct 274 PTLHQSLLDHPARDAHDLSALRLVVTGAAVVPLRLVERLRNELRIATVLTAYGLSEASGI 333 Query 326 GTMCRPEDDAVTVATTCGRPFADFELRIADD----GEVLLRGPNVMVGYLDDTEATAAAI 381 TMCR D VATT GR ELRI + GEV +RG +VM GY +D + TAA + Sbjct 334 VTMCRRGDAPEVVATTSGRAIPGTELRILAEPGAPGEVQVRGFHVMGGYFEDPDTTAATM 393 Query 382 DADGWLHTGDIGAVDQAGNLRITDRLKDMYICGGFNVYPAEVEQVLARMDGVADAAVIGV 441 DGWL TGD+G +D AGNLRITDR+KDM+I GGFN YPAE+EQ+L VAD AV+G+ Sbjct 394 TEDGWLRTGDVGVLDAAGNLRITDRIKDMFIVGGFNAYPAEIEQLLGLHPDVADVAVVGI 453 Query 442 PDQRLGEVGRAFVVARPGTGLDEASVIAYTREHLANFKTPRSVRFVDVLPRNAAGKVSKP 501 PD RLGEVG+A+ V R G L +IA++R +ANFK PR+V FV LPRNA+GKV K Sbjct 454 PDPRLGEVGKAYAVRRRGATLTADDLIAWSRREMANFKVPRAVEFVAELPRNASGKVVKG 513 Query 502 QLR 504 +LR Sbjct 514 ELR 516 >gi|291446923|ref|ZP_06586313.1| acyl-CoA synthetase [Streptomyces roseosporus NRRL 15998] gi|291349870|gb|EFE76774.1| acyl-CoA synthetase [Streptomyces roseosporus NRRL 15998] Length=519 Score = 486 bits (1251), Expect = 4e-135, Method: Compositional matrix adjust. Identities = 264/486 (55%), Positives = 322/486 (67%), Gaps = 9/486 (1%) Query 31 RFTSTELRDAVYGAAAALIALGVEPADRVAIWSPNTWHWVVACLAIHHAGAAVVPLNTRY 90 R T EL V AAAA + GVEP DRVAIW+PNT W+V+ L AGA +VPLNTR+ Sbjct 34 RLTYAELGAQVERAAAACMGAGVEPGDRVAIWAPNTTEWIVSALGAVSAGAVLVPLNTRF 93 Query 91 TATEATDILDRAGAPVLFAAGLFLGADRAAGLDRA--ALPALRHVVRVPVEA--DDGTWD 146 TEA IL R+ A +LF G FLG A L RA LP L VV + A D +W Sbjct 94 KGTEAAHILRRSRARLLFVTGTFLGTSYVASLRRAEVKLPDLERVVVLADTAPEDYTSWP 153 Query 147 EFIATGAGA-LDAVAARAAAVAPQDVSDILFTSGTTGRSKGVLCAHRQSLSASASWAANG 205 +F+A G G AV RAAA+AP SDI++TSGTTG KG + H Q+L A W+ Sbjct 154 DFLAAGEGVESSAVRDRAAAIAPSSPSDIIYTSGTTGAPKGAVITHAQTLRAYEIWSDLA 213 Query 206 KITSDDRYLCINPFFHNFGYKAGILACLQTGATLIPHVTFDPLHALRAIERHRITVLPGP 265 + DRYL +NPFFH FGYKAGI+ACL GAT++P F+ L I RI+VLPGP Sbjct 214 GLREGDRYLIVNPFFHTFGYKAGIIACLMRGATMVPQPVFNVDTVLANIAAERISVLPGP 273 Query 266 PTIYQSLLDHPARKDFDLSSLRFAVTGAATVPVVLVERMQSELDIDIVLTAYGLTEANGM 325 PT++QSLLDHPAR DL++LR VTGAA VP+ LVER+++EL I VLTAYGL+EA+G+ Sbjct 274 PTLHQSLLDHPARDAHDLTALRLVVTGAAVVPLQLVERLRNELGIATVLTAYGLSEASGI 333 Query 326 GTMCRPEDDAVTVATTCGRPFADFELRIADD----GEVLLRGPNVMVGYLDDTEATAAAI 381 TMCR D VATT GR E+R+ D GE+ +RG VM GY +D + TAA + Sbjct 334 VTMCRRGDAPEIVATTSGRAIPGTEIRVLADPGAPGEIQVRGFTVMTGYFEDPDTTAATM 393 Query 382 DADGWLHTGDIGAVDQAGNLRITDRLKDMYICGGFNVYPAEVEQVLARMDGVADAAVIGV 441 DGWL TGD+G +D AGNLRITDR+KDM+I GGFN YPAE+EQ+L VAD AVIGV Sbjct 394 TEDGWLRTGDVGVLDPAGNLRITDRIKDMFIVGGFNAYPAEIEQLLGLHPDVADVAVIGV 453 Query 442 PDQRLGEVGRAFVVARPGTGLDEASVIAYTREHLANFKTPRSVRFVDVLPRNAAGKVSKP 501 PD RLGEVG+A+ V R G L +IA++R +ANFK PR+V FV LPRNA+GKV K Sbjct 454 PDPRLGEVGKAYAVRRRGATLTADDLIAWSRREMANFKVPRTVEFVPELPRNASGKVVKG 513 Query 502 QLRELG 507 +LR LG Sbjct 514 ELRGLG 519 >gi|239989906|ref|ZP_04710570.1| acyl-CoA synthetase [Streptomyces roseosporus NRRL 11379] Length=518 Score = 486 bits (1250), Expect = 5e-135, Method: Compositional matrix adjust. Identities = 264/486 (55%), Positives = 322/486 (67%), Gaps = 9/486 (1%) Query 31 RFTSTELRDAVYGAAAALIALGVEPADRVAIWSPNTWHWVVACLAIHHAGAAVVPLNTRY 90 R T EL V AAAA + GVEP DRVAIW+PNT W+V+ L AGA +VPLNTR+ Sbjct 33 RLTYAELGAQVERAAAACMGAGVEPGDRVAIWAPNTTEWIVSALGAVSAGAVLVPLNTRF 92 Query 91 TATEATDILDRAGAPVLFAAGLFLGADRAAGLDRA--ALPALRHVVRVPVEA--DDGTWD 146 TEA IL R+ A +LF G FLG A L RA LP L VV + A D +W Sbjct 93 KGTEAAHILRRSRARLLFVTGTFLGTSYVASLRRAEVKLPDLERVVVLADTAPEDYTSWP 152 Query 147 EFIATGAGA-LDAVAARAAAVAPQDVSDILFTSGTTGRSKGVLCAHRQSLSASASWAANG 205 +F+A G G AV RAAA+AP SDI++TSGTTG KG + H Q+L A W+ Sbjct 153 DFLAAGEGVESSAVRDRAAAIAPSSPSDIIYTSGTTGAPKGAVITHAQTLRAYEIWSDLA 212 Query 206 KITSDDRYLCINPFFHNFGYKAGILACLQTGATLIPHVTFDPLHALRAIERHRITVLPGP 265 + DRYL +NPFFH FGYKAGI+ACL GAT++P F+ L I RI+VLPGP Sbjct 213 GLREGDRYLIVNPFFHTFGYKAGIIACLMRGATMVPQPVFNVDTVLANIAAERISVLPGP 272 Query 266 PTIYQSLLDHPARKDFDLSSLRFAVTGAATVPVVLVERMQSELDIDIVLTAYGLTEANGM 325 PT++QSLLDHPAR DL++LR VTGAA VP+ LVER+++EL I VLTAYGL+EA+G+ Sbjct 273 PTLHQSLLDHPARDAHDLTALRLVVTGAAVVPLQLVERLRNELGIATVLTAYGLSEASGI 332 Query 326 GTMCRPEDDAVTVATTCGRPFADFELRIADD----GEVLLRGPNVMVGYLDDTEATAAAI 381 TMCR D VATT GR E+R+ D GE+ +RG VM GY +D + TAA + Sbjct 333 VTMCRRGDAPEIVATTSGRAIPGTEIRVLADPGAPGEIQVRGFTVMTGYFEDPDTTAATM 392 Query 382 DADGWLHTGDIGAVDQAGNLRITDRLKDMYICGGFNVYPAEVEQVLARMDGVADAAVIGV 441 DGWL TGD+G +D AGNLRITDR+KDM+I GGFN YPAE+EQ+L VAD AVIGV Sbjct 393 TEDGWLRTGDVGVLDPAGNLRITDRIKDMFIVGGFNAYPAEIEQLLGLHPDVADVAVIGV 452 Query 442 PDQRLGEVGRAFVVARPGTGLDEASVIAYTREHLANFKTPRSVRFVDVLPRNAAGKVSKP 501 PD RLGEVG+A+ V R G L +IA++R +ANFK PR+V FV LPRNA+GKV K Sbjct 453 PDPRLGEVGKAYAVRRRGATLTADDLIAWSRREMANFKVPRTVEFVPELPRNASGKVVKG 512 Query 502 QLRELG 507 +LR LG Sbjct 513 ELRGLG 518 >gi|290959588|ref|YP_003490770.1| AMP-binding protein [Streptomyces scabiei 87.22] gi|260649114|emb|CBG72228.1| putative AMP-binding protein [Streptomyces scabiei 87.22] Length=554 Score = 486 bits (1250), Expect = 5e-135, Method: Compositional matrix adjust. Identities = 271/535 (51%), Positives = 346/535 (65%), Gaps = 37/535 (6%) Query 7 TVPAALDRLVRQLPDHTALIAEDRRFTSTELRDAVYGAAAALIALGVEPADRVAIWSPNT 66 TVP + R+ A++ R T EL V AAAA +A GV DRVA+W+PN+ Sbjct 18 TVPGLVRSAARRFGGDEAVVDGRTRVTYAELGARVERAAAACVANGVRTGDRVALWAPNS 77 Query 67 WHWVVACLAIHHAGAAVVPLNTRYTATEATDILDRAGAPVLFAAGLFLGADRAAGLDRAA 126 W+V+ L AGA +VPLNTR+ EA D+L R+ A +LF G FLG A L RAA Sbjct 78 LDWIVSALGAVSAGAVLVPLNTRFKGGEAADVLARSRARLLFVTGTFLGTSYVASLRRAA 137 Query 127 ---------------------LPALRHVVRVPVEADDG-----TWDEFIATGAGALD-AV 159 LPAL H+ +V V ADD TW +F+A+G G + AV Sbjct 138 GADGGRLRARGAGSVCERPGPLPALPHLEQVVVLADDAPADFRTWKDFLASGDGVGERAV 197 Query 160 AARAAAVAPQDVSDILFTSGTTGRSKGVLCAHRQSLSASASWAANGKITSDDRYLCINPF 219 RA A+ SDI+FTSGTTGRSKGV+ +H Q+L A W+ + DRYL +NPF Sbjct 198 RERAEALTGDSPSDIVFTSGTTGRSKGVVISHAQTLRAYEVWSELAGLRRGDRYLIVNPF 257 Query 220 FHNFGYKAGILACLQTGATLIPHVTFDPLHALRAIERHRITVLPGPPTIYQSLLDHPARK 279 FH FGYKAG++ACL GAT+IP F+ A+ + R+TVLPGPPT++QSLLDHPAR Sbjct 258 FHTFGYKAGVIACLMRGATMIPQPVFNVETAMANVAAERVTVLPGPPTLHQSLLDHPARD 317 Query 280 DFDLSSLRFAVTGAATVPVVLVERMQSELDIDIVLTAYGLTEANGMGTMCRPEDDAVTVA 339 D+DL SLR VTGAA VP+ LVER+++EL +D VLTAYGL+EA+G+ TMCR D+ +A Sbjct 318 DYDLGSLRLVVTGAAVVPLRLVERLRAELRVDTVLTAYGLSEASGIVTMCRRGDEPSVIA 377 Query 340 TTCGRPFADFELRIAD----------DGEVLLRGPNVMVGYLDDTEATAAAIDADGWLHT 389 +T GR E+R+ D GEVL+RG NVM GY +D TA A+ +DGWL T Sbjct 378 STSGRAIPGTEVRVVDPLGSALPAGSPGEVLVRGFNVMRGYFEDPAETARAVTSDGWLRT 437 Query 390 GDIGAVDQAGNLRITDRLKDMYICGGFNVYPAEVEQVLARMDGVADAAVIGVPDQRLGEV 449 GD+G +D+AGNLRITDR+KDM+I GGFN YPAE+EQ+L VAD AV+GVPD RLGEV Sbjct 438 GDVGVLDEAGNLRITDRIKDMFIVGGFNAYPAEIEQLLGLHPDVADVAVVGVPDTRLGEV 497 Query 450 GRAFVVARPGTGLDEASVIAYTREHLANFKTPRSVRFVDVLPRNAAGKVSKPQLR 504 GRA+VV RPG+ + +IA++R +AN+K PRSV F+ LPRNA+GKV K +LR Sbjct 498 GRAYVVRRPGSHVTADDLIAWSRREMANYKVPRSVEFMRELPRNASGKVVKGELR 552 >gi|182436807|ref|YP_001824526.1| acyl-CoA synthetase [Streptomyces griseus subsp. griseus NBRC 13350] gi|178465323|dbj|BAG19843.1| putative fatty acid:CoA ligase [Streptomyces griseus subsp. griseus NBRC 13350] Length=518 Score = 484 bits (1247), Expect = 1e-134, Method: Compositional matrix adjust. Identities = 262/483 (55%), Positives = 325/483 (68%), Gaps = 9/483 (1%) Query 31 RFTSTELRDAVYGAAAALIALGVEPADRVAIWSPNTWHWVVACLAIHHAGAAVVPLNTRY 90 R + EL + V AAAA +A GVEP DRVAIW+PNT W+++ L AGA +VPLNTR+ Sbjct 33 RLSYAELGERVERAAAACLASGVEPGDRVAIWAPNTPDWIISALGAVTAGAVLVPLNTRF 92 Query 91 TATEATDILDRAGAPVLFAAGLFLGADRAAGLDRAA--LPALRHVVRVPVEA--DDGTWD 146 TEA +L R+ A +LF G FLG A L RA LP L VV + A D +W Sbjct 93 KGTEAAYVLRRSRARLLFVTGTFLGTSYVASLRRAEVRLPDLERVVVLADTAPEDYTSWP 152 Query 147 EFIATGAGAL-DAVAARAAAVAPQDVSDILFTSGTTGRSKGVLCAHRQSLSASASWAANG 205 +F+A G G L AV RAAA+AP D SDI++TSGTTG KG + H Q+L A W+ Sbjct 153 DFLAAGEGVLPSAVRERAAAIAPSDPSDIIYTSGTTGAPKGAVITHAQTLRAYGIWSDLA 212 Query 206 KITSDDRYLCINPFFHNFGYKAGILACLQTGATLIPHVTFDPLHALRAIERHRITVLPGP 265 + DRYL +NPFFH FGYKAGI+ACL GAT++P F+ L I RI+VLPGP Sbjct 213 GLREGDRYLIVNPFFHTFGYKAGIIACLMRGATMVPQPVFNVDTVLANIAAERISVLPGP 272 Query 266 PTIYQSLLDHPARKDFDLSSLRFAVTGAATVPVVLVERMQSELDIDIVLTAYGLTEANGM 325 PT++QSLLDHPAR DLS+LR VTGAA VP+ LVER+++EL I VLTAYGL+EA+G+ Sbjct 273 PTLHQSLLDHPARDAHDLSALRLVVTGAAVVPLRLVERLRNELRIATVLTAYGLSEASGI 332 Query 326 GTMCRPEDDAVTVATTCGRPFADFELRIADD----GEVLLRGPNVMVGYLDDTEATAAAI 381 TMCR D VATT GR ELR+ + GEV +RG +VM GY +D + TAA + Sbjct 333 VTMCRRGDAPEVVATTSGRAIPGTELRVLAEPGAPGEVQVRGFHVMGGYFEDPDTTAATM 392 Query 382 DADGWLHTGDIGAVDQAGNLRITDRLKDMYICGGFNVYPAEVEQVLARMDGVADAAVIGV 441 DGWL TGD+G +D AGNLRITDR+KDM+I GGFN YPAE+EQ+L VAD AV+G+ Sbjct 393 TEDGWLRTGDVGVLDAAGNLRITDRIKDMFIVGGFNAYPAEIEQLLGLHPDVADVAVVGI 452 Query 442 PDQRLGEVGRAFVVARPGTGLDEASVIAYTREHLANFKTPRSVRFVDVLPRNAAGKVSKP 501 PD RLGEVG+A+ V R G L +IA++R +ANFK PR+V FV LPRNA+GKV K Sbjct 453 PDPRLGEVGKAYAVRRRGATLTADDLIAWSRREMANFKVPRAVEFVAELPRNASGKVVKG 512 Query 502 QLR 504 +LR Sbjct 513 ELR 515 Lambda K H 0.322 0.137 0.410 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 1098731157348 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40