BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv3608c Length=280 Score E Sequences producing significant alignments: (Bits) Value gi|31794784|ref|NP_857277.1| dihydropteroate synthase [Mycobacte... 542 2e-152 gi|308232510|ref|ZP_07664102.1| dihydropteroate synthase 1 folp ... 533 1e-149 gi|15843220|ref|NP_338257.1| dihydropteroate synthase [Mycobacte... 528 3e-148 gi|41406548|ref|NP_959384.1| hypothetical protein MAP0450 [Mycob... 422 2e-116 gi|336458520|gb|EGO37491.1| dihydropteroate synthase [Mycobacter... 418 5e-115 gi|183985079|ref|YP_001853370.1| dihydropteroate synthase 1 FolP... 416 2e-114 gi|15827021|ref|NP_301284.1| dihydropteroate synthase [Mycobacte... 416 3e-114 gi|5832727|dbj|BAA84081.1| dihydropteroate synthase [Mycobacteri... 415 3e-114 gi|5832723|dbj|BAA84079.1| dihydropteroate synthase [Mycobacteri... 414 8e-114 gi|5832717|dbj|BAA84076.1| dihydropteroate synthase [Mycobacteri... 412 3e-113 gi|118464913|ref|YP_879824.1| dihydropteroate synthase [Mycobact... 411 4e-113 gi|240172851|ref|ZP_04751510.1| dihydropteroate synthase 1 FolP1... 409 2e-112 gi|118619364|ref|YP_907696.1| dihydropteroate synthase 1 FolP1 [... 409 3e-112 gi|342862041|ref|ZP_08718685.1| dihydropteroate synthase [Mycoba... 407 7e-112 gi|254822683|ref|ZP_05227684.1| hypothetical protein MintA_22329... 407 9e-112 gi|118472394|ref|YP_890324.1| dihydropteroate synthase [Mycobact... 395 3e-108 gi|126437718|ref|YP_001073409.1| dihydropteroate synthase [Mycob... 385 6e-105 gi|108801731|ref|YP_641928.1| dihydropteroate synthase [Mycobact... 384 1e-104 gi|296166674|ref|ZP_06849099.1| dihydropteroate synthase [Mycoba... 383 2e-104 gi|145222010|ref|YP_001132688.1| dihydropteroate synthase [Mycob... 374 6e-102 gi|333992537|ref|YP_004525151.1| dihydropteroate synthase 1 FolP... 374 1e-101 gi|315446250|ref|YP_004079129.1| dihydropteroate synthase [Mycob... 373 2e-101 gi|120406318|ref|YP_956147.1| dihydropteroate synthase [Mycobact... 370 1e-100 gi|226363735|ref|YP_002781517.1| dihydropteroate synthase [Rhodo... 322 4e-86 gi|169627639|ref|YP_001701288.1| dihydropteroate synthase [Mycob... 321 7e-86 gi|312138054|ref|YP_004005390.1| dihydropteroate synthase folp1 ... 318 6e-85 gi|54022364|ref|YP_116606.1| putative dihydropteroate synthase [... 318 6e-85 gi|111021381|ref|YP_704353.1| dihydropteroate synthase [Rhodococ... 317 1e-84 gi|298527086|ref|ZP_07014495.1| dihydropteroate synthase [Mycoba... 315 4e-84 gi|226304116|ref|YP_002764074.1| dihydropteroate synthase [Rhodo... 309 2e-82 gi|229494353|ref|ZP_04388116.1| dihydropteroate synthase [Rhodoc... 309 4e-82 gi|326384085|ref|ZP_08205768.1| dihydropteroate synthase [Gordon... 306 3e-81 gi|289759767|ref|ZP_06519145.1| dihydropteroate synthase 1 folp ... 305 5e-81 gi|289748122|ref|ZP_06507500.1| dihydropteroate synthase 1 folp ... 304 1e-80 gi|343924376|ref|ZP_08763926.1| dihydropteroate synthase [Gordon... 301 6e-80 gi|333917991|ref|YP_004491572.1| dihydropteroate synthase [Amyco... 293 1e-77 gi|262203870|ref|YP_003275078.1| dihydropteroate synthase [Gordo... 289 3e-76 gi|325000125|ref|ZP_08121237.1| 7,8-dihydropteroate synthase (pa... 288 5e-76 gi|284989215|ref|YP_003407769.1| dihydropteroate synthase [Geode... 288 8e-76 gi|302530787|ref|ZP_07283129.1| dihydropteroate synthase [Strept... 279 3e-73 gi|302870316|ref|YP_003838953.1| dihydropteroate synthase [Micro... 276 2e-72 gi|291006243|ref|ZP_06564216.1| 7,8-dihydropteroate synthase (pa... 275 5e-72 gi|315503407|ref|YP_004082294.1| dihydropteroate synthase [Micro... 275 6e-72 gi|134097011|ref|YP_001102672.1| 7,8-dihydropteroate synthase (p... 273 2e-71 gi|330470501|ref|YP_004408244.1| dihydropteroate synthase [Verru... 271 6e-71 gi|333025307|ref|ZP_08453371.1| putative dihydropteroate synthas... 271 9e-71 gi|145596806|ref|YP_001161103.1| dihydropteroate synthase [Salin... 271 1e-70 gi|318061590|ref|ZP_07980311.1| dihydropteroate synthase [Strept... 270 1e-70 gi|170780557|ref|YP_001708889.1| putative dihydropteroate syntha... 268 7e-70 gi|297563887|ref|YP_003682860.1| dihydropteroate synthase [Nocar... 268 9e-70 >gi|31794784|ref|NP_857277.1| dihydropteroate synthase [Mycobacterium bovis AF2122/97] gi|57117134|ref|YP_177997.1| dihydropteroate synthase [Mycobacterium tuberculosis H37Rv] gi|121639527|ref|YP_979751.1| dihydropteroate synthase [Mycobacterium bovis BCG str. Pasteur 1173P2] 52 more sequence titles Length=280 Score = 542 bits (1397), Expect = 2e-152, Method: Compositional matrix adjust. Identities = 279/280 (99%), Positives = 280/280 (100%), Gaps = 0/280 (0%) Query 1 VSPAPVQVMGVLNVTDDSFSDGGCYLDLDDAVKHGLAMAAAGAGIVDVGGESSRPGATRV 60 +SPAPVQVMGVLNVTDDSFSDGGCYLDLDDAVKHGLAMAAAGAGIVDVGGESSRPGATRV Sbjct 1 MSPAPVQVMGVLNVTDDSFSDGGCYLDLDDAVKHGLAMAAAGAGIVDVGGESSRPGATRV 60 Query 61 DPAVETSRVIPVVKELAAQGITVSIDTMRADVARAALQNGAQMVNDVSGGRADPAMGPLL 120 DPAVETSRVIPVVKELAAQGITVSIDTMRADVARAALQNGAQMVNDVSGGRADPAMGPLL Sbjct 61 DPAVETSRVIPVVKELAAQGITVSIDTMRADVARAALQNGAQMVNDVSGGRADPAMGPLL 120 Query 121 AEADVPWVLMHWRAVSADTPHVPVRYGNVVAEVRADLLASVADAVAAGVDPARLVLDPGL 180 AEADVPWVLMHWRAVSADTPHVPVRYGNVVAEVRADLLASVADAVAAGVDPARLVLDPGL Sbjct 121 AEADVPWVLMHWRAVSADTPHVPVRYGNVVAEVRADLLASVADAVAAGVDPARLVLDPGL 180 Query 181 GFAKTAQHNWAILHALPELVATGIPVLVGASRKRFLGALLAGPDGVMRPTDGRDTATAVI 240 GFAKTAQHNWAILHALPELVATGIPVLVGASRKRFLGALLAGPDGVMRPTDGRDTATAVI Sbjct 181 GFAKTAQHNWAILHALPELVATGIPVLVGASRKRFLGALLAGPDGVMRPTDGRDTATAVI 240 Query 241 SALAALHGAWGVRVHDVRASVDAIKVVEAWMGAERIERDG 280 SALAALHGAWGVRVHDVRASVDAIKVVEAWMGAERIERDG Sbjct 241 SALAALHGAWGVRVHDVRASVDAIKVVEAWMGAERIERDG 280 >gi|308232510|ref|ZP_07664102.1| dihydropteroate synthase 1 folp [Mycobacterium tuberculosis SUMu001] gi|308369171|ref|ZP_07416830.2| dihydropteroate synthase 1 folp [Mycobacterium tuberculosis SUMu002] gi|308371395|ref|ZP_07424837.2| dihydropteroate synthase 1 folp [Mycobacterium tuberculosis SUMu003] 21 more sequence titles Length=275 Score = 533 bits (1373), Expect = 1e-149, Method: Compositional matrix adjust. Identities = 274/275 (99%), Positives = 275/275 (100%), Gaps = 0/275 (0%) Query 6 VQVMGVLNVTDDSFSDGGCYLDLDDAVKHGLAMAAAGAGIVDVGGESSRPGATRVDPAVE 65 +QVMGVLNVTDDSFSDGGCYLDLDDAVKHGLAMAAAGAGIVDVGGESSRPGATRVDPAVE Sbjct 1 MQVMGVLNVTDDSFSDGGCYLDLDDAVKHGLAMAAAGAGIVDVGGESSRPGATRVDPAVE 60 Query 66 TSRVIPVVKELAAQGITVSIDTMRADVARAALQNGAQMVNDVSGGRADPAMGPLLAEADV 125 TSRVIPVVKELAAQGITVSIDTMRADVARAALQNGAQMVNDVSGGRADPAMGPLLAEADV Sbjct 61 TSRVIPVVKELAAQGITVSIDTMRADVARAALQNGAQMVNDVSGGRADPAMGPLLAEADV 120 Query 126 PWVLMHWRAVSADTPHVPVRYGNVVAEVRADLLASVADAVAAGVDPARLVLDPGLGFAKT 185 PWVLMHWRAVSADTPHVPVRYGNVVAEVRADLLASVADAVAAGVDPARLVLDPGLGFAKT Sbjct 121 PWVLMHWRAVSADTPHVPVRYGNVVAEVRADLLASVADAVAAGVDPARLVLDPGLGFAKT 180 Query 186 AQHNWAILHALPELVATGIPVLVGASRKRFLGALLAGPDGVMRPTDGRDTATAVISALAA 245 AQHNWAILHALPELVATGIPVLVGASRKRFLGALLAGPDGVMRPTDGRDTATAVISALAA Sbjct 181 AQHNWAILHALPELVATGIPVLVGASRKRFLGALLAGPDGVMRPTDGRDTATAVISALAA 240 Query 246 LHGAWGVRVHDVRASVDAIKVVEAWMGAERIERDG 280 LHGAWGVRVHDVRASVDAIKVVEAWMGAERIERDG Sbjct 241 LHGAWGVRVHDVRASVDAIKVVEAWMGAERIERDG 275 >gi|15843220|ref|NP_338257.1| dihydropteroate synthase [Mycobacterium tuberculosis CDC1551] gi|13883575|gb|AAK48071.1| dihydropteroate synthase [Mycobacterium tuberculosis CDC1551] Length=272 Score = 528 bits (1360), Expect = 3e-148, Method: Compositional matrix adjust. Identities = 272/272 (100%), Positives = 272/272 (100%), Gaps = 0/272 (0%) Query 9 MGVLNVTDDSFSDGGCYLDLDDAVKHGLAMAAAGAGIVDVGGESSRPGATRVDPAVETSR 68 MGVLNVTDDSFSDGGCYLDLDDAVKHGLAMAAAGAGIVDVGGESSRPGATRVDPAVETSR Sbjct 1 MGVLNVTDDSFSDGGCYLDLDDAVKHGLAMAAAGAGIVDVGGESSRPGATRVDPAVETSR 60 Query 69 VIPVVKELAAQGITVSIDTMRADVARAALQNGAQMVNDVSGGRADPAMGPLLAEADVPWV 128 VIPVVKELAAQGITVSIDTMRADVARAALQNGAQMVNDVSGGRADPAMGPLLAEADVPWV Sbjct 61 VIPVVKELAAQGITVSIDTMRADVARAALQNGAQMVNDVSGGRADPAMGPLLAEADVPWV 120 Query 129 LMHWRAVSADTPHVPVRYGNVVAEVRADLLASVADAVAAGVDPARLVLDPGLGFAKTAQH 188 LMHWRAVSADTPHVPVRYGNVVAEVRADLLASVADAVAAGVDPARLVLDPGLGFAKTAQH Sbjct 121 LMHWRAVSADTPHVPVRYGNVVAEVRADLLASVADAVAAGVDPARLVLDPGLGFAKTAQH 180 Query 189 NWAILHALPELVATGIPVLVGASRKRFLGALLAGPDGVMRPTDGRDTATAVISALAALHG 248 NWAILHALPELVATGIPVLVGASRKRFLGALLAGPDGVMRPTDGRDTATAVISALAALHG Sbjct 181 NWAILHALPELVATGIPVLVGASRKRFLGALLAGPDGVMRPTDGRDTATAVISALAALHG 240 Query 249 AWGVRVHDVRASVDAIKVVEAWMGAERIERDG 280 AWGVRVHDVRASVDAIKVVEAWMGAERIERDG Sbjct 241 AWGVRVHDVRASVDAIKVVEAWMGAERIERDG 272 >gi|41406548|ref|NP_959384.1| hypothetical protein MAP0450 [Mycobacterium avium subsp. paratuberculosis K-10] gi|41394897|gb|AAS02767.1| FolP [Mycobacterium avium subsp. paratuberculosis K-10] Length=270 Score = 422 bits (1086), Expect = 2e-116, Method: Compositional matrix adjust. Identities = 217/267 (82%), Positives = 241/267 (91%), Gaps = 0/267 (0%) Query 6 VQVMGVLNVTDDSFSDGGCYLDLDDAVKHGLAMAAAGAGIVDVGGESSRPGATRVDPAVE 65 +QVMGVLNVTDDSFSDGG YLD D AV HGLA+ A GAGIVDVGGES+RPGATR+DP VE Sbjct 1 MQVMGVLNVTDDSFSDGGRYLDPDKAVAHGLALVAEGAGIVDVGGESTRPGATRIDPRVE 60 Query 66 TSRVIPVVKELAAQGITVSIDTMRADVARAALQNGAQMVNDVSGGRADPAMGPLLAEADV 125 TSRV+PVVK LAA+G+TVSIDTM ADVARAAL +GA++VNDVSGGRADPAM PLLAEA V Sbjct 61 TSRVVPVVKALAAEGVTVSIDTMHADVARAALGSGARIVNDVSGGRADPAMAPLLAEAKV 120 Query 126 PWVLMHWRAVSADTPHVPVRYGNVVAEVRADLLASVADAVAAGVDPARLVLDPGLGFAKT 185 PWVLMHWR+VSA+ PH +Y +VVAEVRA+LLASV AVAAGVD ARL++DPGLGFAKT Sbjct 121 PWVLMHWRSVSAERPHAAPQYRDVVAEVRAELLASVDAAVAAGVDSARLMIDPGLGFAKT 180 Query 186 AQHNWAILHALPELVATGIPVLVGASRKRFLGALLAGPDGVMRPTDGRDTATAVISALAA 245 QHNWA+LHALP+LVATGIPVL+GASRKRFLG LLAGPDG RP DGR+TATAVISALAA Sbjct 181 GQHNWALLHALPQLVATGIPVLLGASRKRFLGTLLAGPDGTPRPPDGRETATAVISALAA 240 Query 246 LHGAWGVRVHDVRASVDAIKVVEAWMG 272 LHGAWGVRVHDVRA+VDA+KV+ AWMG Sbjct 241 LHGAWGVRVHDVRATVDALKVLGAWMG 267 >gi|336458520|gb|EGO37491.1| dihydropteroate synthase [Mycobacterium avium subsp. paratuberculosis S397] Length=267 Score = 418 bits (1074), Expect = 5e-115, Method: Compositional matrix adjust. Identities = 215/264 (82%), Positives = 238/264 (91%), Gaps = 0/264 (0%) Query 9 MGVLNVTDDSFSDGGCYLDLDDAVKHGLAMAAAGAGIVDVGGESSRPGATRVDPAVETSR 68 MGVLNVTDDSFSDGG YLD D AV HGLA+ A GAGIVDVGGES+RPGATR+DP VETSR Sbjct 1 MGVLNVTDDSFSDGGRYLDPDKAVAHGLALVAEGAGIVDVGGESTRPGATRIDPRVETSR 60 Query 69 VIPVVKELAAQGITVSIDTMRADVARAALQNGAQMVNDVSGGRADPAMGPLLAEADVPWV 128 V+PVVK LAA+G+TVSIDTM ADVARAAL +GA++VNDVSGGRADPAM PLLAEA VPWV Sbjct 61 VVPVVKALAAEGVTVSIDTMHADVARAALGSGARIVNDVSGGRADPAMAPLLAEAKVPWV 120 Query 129 LMHWRAVSADTPHVPVRYGNVVAEVRADLLASVADAVAAGVDPARLVLDPGLGFAKTAQH 188 LMHWR+VSA+ PH +Y +VVAEVRA+LLASV AVAAGVD ARL++DPGLGFAKT QH Sbjct 121 LMHWRSVSAERPHAAPQYRDVVAEVRAELLASVDAAVAAGVDSARLMIDPGLGFAKTGQH 180 Query 189 NWAILHALPELVATGIPVLVGASRKRFLGALLAGPDGVMRPTDGRDTATAVISALAALHG 248 NWA+LHALP+LVATGIPVL+GASRKRFLG LLAGPDG RP DGR+TATAVISALAALHG Sbjct 181 NWALLHALPQLVATGIPVLLGASRKRFLGTLLAGPDGTPRPPDGRETATAVISALAALHG 240 Query 249 AWGVRVHDVRASVDAIKVVEAWMG 272 AWGVRVHDVRA+VDA+KV+ AWMG Sbjct 241 AWGVRVHDVRATVDALKVLGAWMG 264 >gi|183985079|ref|YP_001853370.1| dihydropteroate synthase 1 FolP1 [Mycobacterium marinum M] gi|183178405|gb|ACC43515.1| dihydropteroate synthase 1 FolP1 [Mycobacterium marinum M] Length=280 Score = 416 bits (1069), Expect = 2e-114, Method: Compositional matrix adjust. Identities = 214/280 (77%), Positives = 239/280 (86%), Gaps = 0/280 (0%) Query 1 VSPAPVQVMGVLNVTDDSFSDGGCYLDLDDAVKHGLAMAAAGAGIVDVGGESSRPGATRV 60 +S PVQVMGVLNVT+DSFSDGG Y D A++HGLA+AA GA I+DVGGES+RPGA RV Sbjct 1 MSSRPVQVMGVLNVTNDSFSDGGRYCDEAKAIEHGLALAAEGADIIDVGGESTRPGAARV 60 Query 61 DPAVETSRVIPVVKELAAQGITVSIDTMRADVARAALQNGAQMVNDVSGGRADPAMGPLL 120 DPAVE SRV+PV+KELAA+GI VSIDT RA VA AL NGAQ+VNDVSGGRADPAM PL+ Sbjct 61 DPAVEASRVLPVIKELAARGIKVSIDTTRAAVACEALHNGAQIVNDVSGGRADPAMAPLV 120 Query 121 AEADVPWVLMHWRAVSADTPHVPVRYGNVVAEVRADLLASVADAVAAGVDPARLVLDPGL 180 AEA VPWVLMHWR VS D PH Y +VVAEVRA+LL +V DA+AAGV P+ L++DPGL Sbjct 121 AEAGVPWVLMHWRPVSDDNPHQVPNYRDVVAEVRAELLTAVDDAIAAGVGPSNLMIDPGL 180 Query 181 GFAKTAQHNWAILHALPELVATGIPVLVGASRKRFLGALLAGPDGVMRPTDGRDTATAVI 240 GFAK QHNW +LHALPELVATGIPVLVGASRKRFLG+LLAGPDG +RP DGR+TATAVI Sbjct 181 GFAKAGQHNWTLLHALPELVATGIPVLVGASRKRFLGSLLAGPDGAVRPPDGRETATAVI 240 Query 241 SALAALHGAWGVRVHDVRASVDAIKVVEAWMGAERIERDG 280 SALAALHGAWGVRVHDVRASVDA+KVV+AW AER DG Sbjct 241 SALAALHGAWGVRVHDVRASVDALKVVDAWQRAERTGHDG 280 >gi|15827021|ref|NP_301284.1| dihydropteroate synthase [Mycobacterium leprae TN] gi|221229499|ref|YP_002502915.1| dihydropteroate synthase [Mycobacterium leprae Br4923] gi|85681931|sp|P0C0X1.1|DHPS1_MYCLE RecName: Full=Dihydropteroate synthase 1; Short=DHPS 1; AltName: Full=Dihydropteroate pyrophosphorylase 1 6 more sequence titles Length=284 Score = 416 bits (1068), Expect = 3e-114, Method: Compositional matrix adjust. Identities = 218/284 (77%), Positives = 245/284 (87%), Gaps = 4/284 (1%) Query 1 VSPAPVQVMGVLNVTDDSFSDGGCYLDLDDAVKHGLAMAAAGAGIVDVGGESSRPGATRV 60 +S APVQV+GVLNVTD+SFSDGG YLD DDAV+HGLAM A GA IVDVGGES+RPGA R Sbjct 1 MSLAPVQVIGVLNVTDNSFSDGGRYLDPDDAVQHGLAMVAEGAAIVDVGGESTRPGAIRT 60 Query 61 DPAVETSRVIPVVKELAAQGITVSIDTMRADVARAALQNGAQMVNDVSGGRADPAMGPLL 120 DP VE SR++PVVKELAAQGITVSIDT RADVARAALQ+GA++VNDVSGGRADPAM PL+ Sbjct 61 DPRVELSRIVPVVKELAAQGITVSIDTTRADVARAALQSGARIVNDVSGGRADPAMAPLV 120 Query 121 AEADVPWVLMHWRAVSADTPHVPVRYGNVVAEVRADLLASVADAVAAGVDPARLVLDPGL 180 AEA V WVLMHWR +SA+ P+ Y +VVAEVRADLLA V AVAAGVDP LV+DPGL Sbjct 121 AEAGVAWVLMHWRLMSAERPYEAPNYRDVVAEVRADLLAGVDQAVAAGVDPGSLVIDPGL 180 Query 181 GFAKTAQHNWAILHALPELVATGIPVLVGASRKRFLGALLAGPDGVMRPTDGRDTATAVI 240 GFAKT QHNWA+L+ALPELVATG+P+L+GASRKRFLG LLAG DG +RP DGR+TATAVI Sbjct 181 GFAKTGQHNWALLNALPELVATGVPILLGASRKRFLGRLLAGADGAVRPPDGRETATAVI 240 Query 241 SALAALHGAWGVRVHDVRASVDAIKVVEAWMGA----ERIERDG 280 SALAALHGAWGVRVHDVRASVDA+KVV AW+ A E++ DG Sbjct 241 SALAALHGAWGVRVHDVRASVDALKVVGAWLHAGPQIEKVRCDG 284 >gi|5832727|dbj|BAA84081.1| dihydropteroate synthase [Mycobacterium leprae] Length=284 Score = 415 bits (1067), Expect = 3e-114, Method: Compositional matrix adjust. Identities = 218/284 (77%), Positives = 245/284 (87%), Gaps = 4/284 (1%) Query 1 VSPAPVQVMGVLNVTDDSFSDGGCYLDLDDAVKHGLAMAAAGAGIVDVGGESSRPGATRV 60 +S APVQV+GVLNVTD+SFSDGG YLD DDAV+HGLAM A GA IVDVGGES+RPGA R Sbjct 1 MSLAPVQVIGVLNVTDNSFSDGGRYLDPDDAVQHGLAMVAEGAAIVDVGGESARPGAIRT 60 Query 61 DPAVETSRVIPVVKELAAQGITVSIDTMRADVARAALQNGAQMVNDVSGGRADPAMGPLL 120 DP VE SR++PVVKELAAQGITVSIDT RADVARAALQ+GA++VNDVSGGRADPAM PL+ Sbjct 61 DPRVELSRIVPVVKELAAQGITVSIDTTRADVARAALQSGARIVNDVSGGRADPAMAPLV 120 Query 121 AEADVPWVLMHWRAVSADTPHVPVRYGNVVAEVRADLLASVADAVAAGVDPARLVLDPGL 180 AEA V WVLMHWR +SA+ P+ Y +VVAEVRADLLA V AVAAGVDP LV+DPGL Sbjct 121 AEAGVAWVLMHWRLMSAERPYEAPNYRDVVAEVRADLLAGVDQAVAAGVDPGSLVIDPGL 180 Query 181 GFAKTAQHNWAILHALPELVATGIPVLVGASRKRFLGALLAGPDGVMRPTDGRDTATAVI 240 GFAKT QHNWA+L+ALPELVATG+P+L+GASRKRFLG LLAG DG +RP DGR+TATAVI Sbjct 181 GFAKTGQHNWALLNALPELVATGVPILLGASRKRFLGRLLAGADGAVRPPDGRETATAVI 240 Query 241 SALAALHGAWGVRVHDVRASVDAIKVVEAWMGA----ERIERDG 280 SALAALHGAWGVRVHDVRASVDA+KVV AW+ A E++ DG Sbjct 241 SALAALHGAWGVRVHDVRASVDALKVVGAWLHAGPQIEKVRCDG 284 >gi|5832723|dbj|BAA84079.1| dihydropteroate synthase [Mycobacterium leprae] gi|5832725|dbj|BAA84080.1| dihydropteroate synthase [Mycobacterium leprae] Length=284 Score = 414 bits (1064), Expect = 8e-114, Method: Compositional matrix adjust. Identities = 218/284 (77%), Positives = 244/284 (86%), Gaps = 4/284 (1%) Query 1 VSPAPVQVMGVLNVTDDSFSDGGCYLDLDDAVKHGLAMAAAGAGIVDVGGESSRPGATRV 60 +S APVQV+GVLNVTD+SFSDGG YLD DDAV+HGLAM A GA IVDVGGES RPGA R Sbjct 1 MSLAPVQVIGVLNVTDNSFSDGGRYLDPDDAVQHGLAMVAEGAAIVDVGGESIRPGAIRT 60 Query 61 DPAVETSRVIPVVKELAAQGITVSIDTMRADVARAALQNGAQMVNDVSGGRADPAMGPLL 120 DP VE SR++PVVKELAAQGITVSIDT RADVARAALQ+GA++VNDVSGGRADPAM PL+ Sbjct 61 DPRVELSRIVPVVKELAAQGITVSIDTTRADVARAALQSGARIVNDVSGGRADPAMAPLV 120 Query 121 AEADVPWVLMHWRAVSADTPHVPVRYGNVVAEVRADLLASVADAVAAGVDPARLVLDPGL 180 AEA V WVLMHWR +SA+ P+ Y +VVAEVRADLLA V AVAAGVDP LV+DPGL Sbjct 121 AEAGVAWVLMHWRLMSAERPYEAPNYRDVVAEVRADLLAGVDQAVAAGVDPGSLVIDPGL 180 Query 181 GFAKTAQHNWAILHALPELVATGIPVLVGASRKRFLGALLAGPDGVMRPTDGRDTATAVI 240 GFAKT QHNWA+L+ALPELVATG+P+L+GASRKRFLG LLAG DG +RP DGR+TATAVI Sbjct 181 GFAKTGQHNWALLNALPELVATGVPILLGASRKRFLGRLLAGADGAVRPPDGRETATAVI 240 Query 241 SALAALHGAWGVRVHDVRASVDAIKVVEAWMGA----ERIERDG 280 SALAALHGAWGVRVHDVRASVDA+KVV AW+ A E++ DG Sbjct 241 SALAALHGAWGVRVHDVRASVDALKVVGAWLHAGPQIEKVRCDG 284 >gi|5832717|dbj|BAA84076.1| dihydropteroate synthase [Mycobacterium leprae] gi|5832719|dbj|BAA84077.1| dihydropteroate synthase [Mycobacterium leprae] gi|5832721|dbj|BAA84078.1| dihydropteroate synthase [Mycobacterium leprae] Length=284 Score = 412 bits (1059), Expect = 3e-113, Method: Compositional matrix adjust. Identities = 217/284 (77%), Positives = 244/284 (86%), Gaps = 4/284 (1%) Query 1 VSPAPVQVMGVLNVTDDSFSDGGCYLDLDDAVKHGLAMAAAGAGIVDVGGESSRPGATRV 60 +S APVQV+GVLNVTD+SFSDGG YLD DDAV+HGLAM A GA IVDVGGES+R GA R Sbjct 1 MSLAPVQVIGVLNVTDNSFSDGGRYLDPDDAVQHGLAMVAEGAAIVDVGGESTRLGAIRT 60 Query 61 DPAVETSRVIPVVKELAAQGITVSIDTMRADVARAALQNGAQMVNDVSGGRADPAMGPLL 120 DP VE SR++PVVKELAAQGITVSIDT RADVARAALQ+GA++VNDVSGGRADPAM PL+ Sbjct 61 DPRVELSRIVPVVKELAAQGITVSIDTTRADVARAALQSGARIVNDVSGGRADPAMAPLV 120 Query 121 AEADVPWVLMHWRAVSADTPHVPVRYGNVVAEVRADLLASVADAVAAGVDPARLVLDPGL 180 AEA V WVLMHWR +SA+ P+ Y +VVAEVRADLLA V AVAAGVDP LV+DPGL Sbjct 121 AEAGVAWVLMHWRLMSAERPYEAPNYRDVVAEVRADLLAGVDQAVAAGVDPGSLVIDPGL 180 Query 181 GFAKTAQHNWAILHALPELVATGIPVLVGASRKRFLGALLAGPDGVMRPTDGRDTATAVI 240 GFAKT QHNWA+L+ALPELVATG+P+L+GASRKRFLG LLAG DG +RP DGR+TATAVI Sbjct 181 GFAKTGQHNWALLNALPELVATGVPILLGASRKRFLGRLLAGADGAVRPPDGRETATAVI 240 Query 241 SALAALHGAWGVRVHDVRASVDAIKVVEAWMGA----ERIERDG 280 SALAALHGAWGVRVHDVRASVDA+KVV AW+ A E++ DG Sbjct 241 SALAALHGAWGVRVHDVRASVDALKVVGAWLHAGPQIEKVRCDG 284 >gi|118464913|ref|YP_879824.1| dihydropteroate synthase [Mycobacterium avium 104] gi|254773203|ref|ZP_05214719.1| hypothetical protein MaviaA2_00776 [Mycobacterium avium subsp. avium ATCC 25291] gi|118166200|gb|ABK67097.1| dihydropteroate synthase [Mycobacterium avium 104] Length=264 Score = 411 bits (1057), Expect = 4e-113, Method: Compositional matrix adjust. Identities = 211/261 (81%), Positives = 235/261 (91%), Gaps = 0/261 (0%) Query 12 LNVTDDSFSDGGCYLDLDDAVKHGLAMAAAGAGIVDVGGESSRPGATRVDPAVETSRVIP 71 +NVTDDSFSDGG YLD D AV HGLA+ A GAGIVDVGGES+RPGATR+DP VETSRV+P Sbjct 1 MNVTDDSFSDGGRYLDPDKAVAHGLALVAEGAGIVDVGGESTRPGATRIDPRVETSRVVP 60 Query 72 VVKELAAQGITVSIDTMRADVARAALQNGAQMVNDVSGGRADPAMGPLLAEADVPWVLMH 131 VVK LAA+G+TVSIDTM ADVARAAL +GA++VNDVSGGRADPAM PLLAEA VPWVLMH Sbjct 61 VVKALAAEGVTVSIDTMHADVARAALGSGARIVNDVSGGRADPAMAPLLAEAKVPWVLMH 120 Query 132 WRAVSADTPHVPVRYGNVVAEVRADLLASVADAVAAGVDPARLVLDPGLGFAKTAQHNWA 191 WR+VSA+ PH +Y +VVAEVRA+LLASV AVAAGVD ARL++DPGLGFAKT QHNWA Sbjct 121 WRSVSAERPHAAPQYRDVVAEVRAELLASVDAAVAAGVDSARLMIDPGLGFAKTGQHNWA 180 Query 192 ILHALPELVATGIPVLVGASRKRFLGALLAGPDGVMRPTDGRDTATAVISALAALHGAWG 251 +LHALP+LVATGIPVL+GASRKRFLG LLAGPDG RP DGR+TATAVISALAALHGAWG Sbjct 181 LLHALPQLVATGIPVLLGASRKRFLGTLLAGPDGAPRPPDGRETATAVISALAALHGAWG 240 Query 252 VRVHDVRASVDAIKVVEAWMG 272 VRVHDVRA+VDA+KV+ AWMG Sbjct 241 VRVHDVRATVDALKVLGAWMG 261 >gi|240172851|ref|ZP_04751510.1| dihydropteroate synthase 1 FolP1 [Mycobacterium kansasii ATCC 12478] Length=280 Score = 409 bits (1052), Expect = 2e-112, Method: Compositional matrix adjust. Identities = 221/280 (79%), Positives = 246/280 (88%), Gaps = 0/280 (0%) Query 1 VSPAPVQVMGVLNVTDDSFSDGGCYLDLDDAVKHGLAMAAAGAGIVDVGGESSRPGATRV 60 +SPAPVQVMGV+NVTDDSFSDGG YLD AV+HGLA+ A GA IVDVGGES+RPGA RV Sbjct 1 MSPAPVQVMGVVNVTDDSFSDGGRYLDAGGAVEHGLALVADGAHIVDVGGESTRPGAARV 60 Query 61 DPAVETSRVIPVVKELAAQGITVSIDTMRADVARAALQNGAQMVNDVSGGRADPAMGPLL 120 DP VET+RV+PVVK L AQG+TVSIDTM ADVAR+AL+NGAQ+VNDVSGGRADPAM PL+ Sbjct 61 DPGVETARVVPVVKGLVAQGVTVSIDTMHADVARSALENGAQLVNDVSGGRADPAMAPLV 120 Query 121 AEADVPWVLMHWRAVSADTPHVPVRYGNVVAEVRADLLASVADAVAAGVDPARLVLDPGL 180 AEA V WVLMHWR VSA PH +YG+VVA+VRA+LLA+V DAVAAGVDPA+LV+DPGL Sbjct 121 AEAGVVWVLMHWRPVSAANPHQVPQYGDVVAQVRAELLAAVDDAVAAGVDPAKLVIDPGL 180 Query 181 GFAKTAQHNWAILHALPELVATGIPVLVGASRKRFLGALLAGPDGVMRPTDGRDTATAVI 240 GFAKT QHNWA+LHALPELVATG PVL+GASRKRFLG+LLAGPDG RP GR+TATAVI Sbjct 181 GFAKTGQHNWALLHALPELVATGFPVLLGASRKRFLGSLLAGPDGATRPPAGRETATAVI 240 Query 241 SALAALHGAWGVRVHDVRASVDAIKVVEAWMGAERIERDG 280 SALAALHGAWGVRVHDVRA+VDA+KVVEAW E RDG Sbjct 241 SALAALHGAWGVRVHDVRATVDALKVVEAWQRVEGTGRDG 280 >gi|118619364|ref|YP_907696.1| dihydropteroate synthase 1 FolP1 [Mycobacterium ulcerans Agy99] gi|118571474|gb|ABL06225.1| dihydropteroate synthase 1 FolP1 [Mycobacterium ulcerans Agy99] Length=272 Score = 409 bits (1051), Expect = 3e-112, Method: Compositional matrix adjust. Identities = 209/272 (77%), Positives = 233/272 (86%), Gaps = 0/272 (0%) Query 9 MGVLNVTDDSFSDGGCYLDLDDAVKHGLAMAAAGAGIVDVGGESSRPGATRVDPAVETSR 68 MGVLNVT+DSFSDGG Y D A++HGLA+AA GA I+DVGGES+RPGA RVDPAVE SR Sbjct 1 MGVLNVTNDSFSDGGRYCDEAKAIEHGLALAAEGADIIDVGGESTRPGAARVDPAVEASR 60 Query 69 VIPVVKELAAQGITVSIDTMRADVARAALQNGAQMVNDVSGGRADPAMGPLLAEADVPWV 128 V+PV+KELAA+GI VSIDT RA VA AL NGAQ+VNDVSGGRADPAM PL+AEA VPWV Sbjct 61 VLPVIKELAARGIKVSIDTTRAAVACEALHNGAQIVNDVSGGRADPAMAPLVAEASVPWV 120 Query 129 LMHWRAVSADTPHVPVRYGNVVAEVRADLLASVADAVAAGVDPARLVLDPGLGFAKTAQH 188 LMHWR VS D PH Y +VVAEVRA+LL +V DA+AAGV P+ L++DPGLGFAK QH Sbjct 121 LMHWRPVSDDNPHQVPNYRDVVAEVRAELLTAVDDAIAAGVGPSNLMIDPGLGFAKAGQH 180 Query 189 NWAILHALPELVATGIPVLVGASRKRFLGALLAGPDGVMRPTDGRDTATAVISALAALHG 248 NW +LHALPELVATGIPVLVGASRKRFLG+LLAGPDG +RP DGR+TATAVISAL ALHG Sbjct 181 NWTLLHALPELVATGIPVLVGASRKRFLGSLLAGPDGAVRPPDGRETATAVISALGALHG 240 Query 249 AWGVRVHDVRASVDAIKVVEAWMGAERIERDG 280 AWGVRVHDVRASVDA+KVV+AW AER RDG Sbjct 241 AWGVRVHDVRASVDALKVVDAWQRAERTGRDG 272 >gi|342862041|ref|ZP_08718685.1| dihydropteroate synthase [Mycobacterium colombiense CECT 3035] gi|342130581|gb|EGT83890.1| dihydropteroate synthase [Mycobacterium colombiense CECT 3035] Length=283 Score = 407 bits (1047), Expect = 7e-112, Method: Compositional matrix adjust. Identities = 215/280 (77%), Positives = 238/280 (85%), Gaps = 0/280 (0%) Query 1 VSPAPVQVMGVLNVTDDSFSDGGCYLDLDDAVKHGLAMAAAGAGIVDVGGESSRPGATRV 60 +S APVQVMGVLNVTDDSFSDGG YLD AV GLA+ A GA IVDVGGES+RPGATR+ Sbjct 1 MSLAPVQVMGVLNVTDDSFSDGGRYLDPGKAVARGLALVADGADIVDVGGESTRPGATRI 60 Query 61 DPAVETSRVIPVVKELAAQGITVSIDTMRADVARAALQNGAQMVNDVSGGRADPAMGPLL 120 DP VETSRV+PVVKELAAQGITVSIDTM ADVARAAL GA++VNDVSGGRADPAM PLL Sbjct 61 DPGVETSRVVPVVKELAAQGITVSIDTMHADVARAALCAGARIVNDVSGGRADPAMAPLL 120 Query 121 AEADVPWVLMHWRAVSADTPHVPVRYGNVVAEVRADLLASVADAVAAGVDPARLVLDPGL 180 AEA VPWVLMHWR+VSA+ PH YG+VVAEVR +LLA V AV+AGVDP RL++DPGL Sbjct 121 AEAKVPWVLMHWRSVSAERPHAVPHYGDVVAEVRDELLAGVDAAVSAGVDPDRLMIDPGL 180 Query 181 GFAKTAQHNWAILHALPELVATGIPVLVGASRKRFLGALLAGPDGVMRPTDGRDTATAVI 240 GFAKT QHNWA+LHALP+LVATG+PVL+GASRKRFLG LLAG DG RP D R+TATAV+ Sbjct 181 GFAKTGQHNWALLHALPQLVATGVPVLLGASRKRFLGTLLAGADGSPRPPDRRETATAVV 240 Query 241 SALAALHGAWGVRVHDVRASVDAIKVVEAWMGAERIERDG 280 SALAAL+GAWGVRVHDVRA+VDA+KVV AW E G Sbjct 241 SALAALNGAWGVRVHDVRATVDALKVVAAWTDGSHTELAG 280 >gi|254822683|ref|ZP_05227684.1| hypothetical protein MintA_22329 [Mycobacterium intracellulare ATCC 13950] Length=275 Score = 407 bits (1046), Expect = 9e-112, Method: Compositional matrix adjust. Identities = 213/262 (82%), Positives = 232/262 (89%), Gaps = 0/262 (0%) Query 9 MGVLNVTDDSFSDGGCYLDLDDAVKHGLAMAAAGAGIVDVGGESSRPGATRVDPAVETSR 68 MGVLNVTDDSFSDGG YLD D AV HGLA+AA GA IVDVGGES+RPGATRVD VE SR Sbjct 1 MGVLNVTDDSFSDGGRYLDPDKAVAHGLALAADGADIVDVGGESTRPGATRVDARVEASR 60 Query 69 VIPVVKELAAQGITVSIDTMRADVARAALQNGAQMVNDVSGGRADPAMGPLLAEADVPWV 128 V+PVVKEL +QGITVSIDTM ADVARAAL +GA++VNDVSGGRADPAM PLLAEA VPWV Sbjct 61 VVPVVKELFSQGITVSIDTMHADVARAALCSGARIVNDVSGGRADPAMAPLLAEAKVPWV 120 Query 129 LMHWRAVSADTPHVPVRYGNVVAEVRADLLASVADAVAAGVDPARLVLDPGLGFAKTAQH 188 LMHWR+VSA PH Y +VVAEVRA+LLASV AV+AGVDPA+L++DPGLGFAKT QH Sbjct 121 LMHWRSVSAQRPHAAPDYRDVVAEVRAELLASVDAAVSAGVDPAQLMIDPGLGFAKTGQH 180 Query 189 NWAILHALPELVATGIPVLVGASRKRFLGALLAGPDGVMRPTDGRDTATAVISALAALHG 248 NWA+LHALP LVATGIPVL+GASRKRFLG LLAGPDG RP DGR+TATAVISALAALHG Sbjct 181 NWALLHALPRLVATGIPVLLGASRKRFLGTLLAGPDGSPRPPDGRETATAVISALAALHG 240 Query 249 AWGVRVHDVRASVDAIKVVEAW 270 AWGVRVHDVRA+VDA+KVV AW Sbjct 241 AWGVRVHDVRATVDALKVVAAW 262 >gi|118472394|ref|YP_890324.1| dihydropteroate synthase [Mycobacterium smegmatis str. MC2 155] gi|118173681|gb|ABK74577.1| dihydropteroate synthase [Mycobacterium smegmatis str. MC2 155] Length=285 Score = 395 bits (1016), Expect = 3e-108, Method: Compositional matrix adjust. Identities = 200/272 (74%), Positives = 232/272 (86%), Gaps = 0/272 (0%) Query 5 PVQVMGVLNVTDDSFSDGGCYLDLDDAVKHGLAMAAAGAGIVDVGGESSRPGATRVDPAV 64 PVQVMGV+NVT DSFSDGG ++D D AV+HGLA+ AAGA I+DVGGES+RPGATR+DP V Sbjct 13 PVQVMGVVNVTQDSFSDGGKFIDTDRAVEHGLALVAAGAQIIDVGGESTRPGATRIDPGV 72 Query 65 ETSRVIPVVKELAAQGITVSIDTMRADVARAALQNGAQMVNDVSGGRADPAMGPLLAEAD 124 E +RV PV++ELAAQGIT+SIDTM ADVARAAL+ GA +VNDVSGGRADP M +LAEA Sbjct 73 EAARVTPVIRELAAQGITISIDTMHADVARAALEAGAHIVNDVSGGRADPGMAGVLAEAK 132 Query 125 VPWVLMHWRAVSADTPHVPVRYGNVVAEVRADLLASVADAVAAGVDPARLVLDPGLGFAK 184 VPW+LMHWR+V AD PH Y +VVAEVR +LLA+V AV AGV+P RLV+DPGLGFAK Sbjct 133 VPWILMHWRSVDADHPHRVPGYRDVVAEVRTELLAAVDAAVTAGVEPERLVIDPGLGFAK 192 Query 185 TAQHNWAILHALPELVATGIPVLVGASRKRFLGALLAGPDGVMRPTDGRDTATAVISALA 244 TA+HNWA+LHALP+LVATG+PVLVGASRKRFLG LLA DG RP DGR+TATAVIS LA Sbjct 193 TAEHNWALLHALPDLVATGVPVLVGASRKRFLGTLLAAADGTPRPPDGRETATAVISVLA 252 Query 245 ALHGAWGVRVHDVRASVDAIKVVEAWMGAERI 276 A+HGAWGVRVHDV+ASVDA+KV+ AW +I Sbjct 253 AMHGAWGVRVHDVQASVDALKVLGAWTSGGQI 284 >gi|126437718|ref|YP_001073409.1| dihydropteroate synthase [Mycobacterium sp. JLS] gi|126237518|gb|ABO00919.1| Dihydropteroate synthase [Mycobacterium sp. JLS] Length=275 Score = 385 bits (988), Expect = 6e-105, Method: Compositional matrix adjust. Identities = 205/271 (76%), Positives = 232/271 (86%), Gaps = 2/271 (0%) Query 1 VSPAPVQVMGVLNVTDDSFSDGGCYLDLDDAVKHGLAMAAAGAGIVDVGGESSRPGATRV 60 +S VQVMGV+NVTDDSFSDGG +LD AV HG+A+AA GA I+DVGGES+RPGATRV Sbjct 1 MSATAVQVMGVVNVTDDSFSDGGQFLDPGHAVAHGMALAAEGAAIIDVGGESTRPGATRV 60 Query 61 DPAVETSRVIPVVKELAAQGITVSIDTMRADVARAALQNGAQMVNDVSGGRADPAMGPLL 120 DP VE +R+IPVV+ LAA GITVSIDTMRA VA AAL++GA +VNDVSGGRADP M ++ Sbjct 61 DPEVEAARIIPVVEALAAAGITVSIDTMRARVASAALEHGAAIVNDVSGGRADPDMARVV 120 Query 121 AEADVPWVLMHWRAVSADTPH-VPVRYGNVVAEVRADLLASVADAVAAGVDPARLVLDPG 179 A+A VPW+LMHWR+V+A+ PH VPV Y +VV EVR +LLASV AVAAGVDP L++DPG Sbjct 121 ADARVPWILMHWRSVAAERPHQVPV-YDDVVGEVRTELLASVDAAVAAGVDPMNLIIDPG 179 Query 180 LGFAKTAQHNWAILHALPELVATGIPVLVGASRKRFLGALLAGPDGVMRPTDGRDTATAV 239 LGFAKT QHNWA+LHALPELVAT IPVLVGASRKRFLGALLA G +RP DGR+TATAV Sbjct 180 LGFAKTGQHNWALLHALPELVATEIPVLVGASRKRFLGALLADAYGAVRPPDGRETATAV 239 Query 240 ISALAALHGAWGVRVHDVRASVDAIKVVEAW 270 ISALAALHGAWGVRVHDVRASVDAIKVV AW Sbjct 240 ISALAALHGAWGVRVHDVRASVDAIKVVGAW 270 >gi|108801731|ref|YP_641928.1| dihydropteroate synthase [Mycobacterium sp. MCS] gi|119870882|ref|YP_940834.1| dihydropteroate synthase [Mycobacterium sp. KMS] gi|108772150|gb|ABG10872.1| Dihydropteroate synthase [Mycobacterium sp. MCS] gi|119696971|gb|ABL94044.1| Dihydropteroate synthase [Mycobacterium sp. KMS] Length=275 Score = 384 bits (986), Expect = 1e-104, Method: Compositional matrix adjust. Identities = 204/271 (76%), Positives = 232/271 (86%), Gaps = 2/271 (0%) Query 1 VSPAPVQVMGVLNVTDDSFSDGGCYLDLDDAVKHGLAMAAAGAGIVDVGGESSRPGATRV 60 +S VQVMGV+NVTDDSFSDGG +LD AV HG+A+AA GA I+DVGGES+RPGATRV Sbjct 1 MSATAVQVMGVVNVTDDSFSDGGQFLDPGHAVAHGMALAAEGAAIIDVGGESTRPGATRV 60 Query 61 DPAVETSRVIPVVKELAAQGITVSIDTMRADVARAALQNGAQMVNDVSGGRADPAMGPLL 120 DP VE +R+IPVV+ LAA GITVSIDTMRA VA AAL++GA +VNDVSGGRADP M ++ Sbjct 61 DPEVEAARIIPVVEALAAAGITVSIDTMRARVASAALEHGAAIVNDVSGGRADPDMARVV 120 Query 121 AEADVPWVLMHWRAVSADTPH-VPVRYGNVVAEVRADLLASVADAVAAGVDPARLVLDPG 179 A+A VPW+LMHWR+V+A+ PH VPV Y +VV EVR +LLASV AVAAGVDP L++DPG Sbjct 121 ADARVPWILMHWRSVAAERPHQVPV-YDDVVGEVRTELLASVDAAVAAGVDPMNLIIDPG 179 Query 180 LGFAKTAQHNWAILHALPELVATGIPVLVGASRKRFLGALLAGPDGVMRPTDGRDTATAV 239 LGFAKT QHNWA+LHALPELVAT IPVLVGASRKRFLGALLA G +RP DGR+TATAV Sbjct 180 LGFAKTGQHNWALLHALPELVATEIPVLVGASRKRFLGALLADAYGAVRPPDGRETATAV 239 Query 240 ISALAALHGAWGVRVHDVRASVDAIKVVEAW 270 ISALAALHGAWGVRVHDVRASVDA+KVV AW Sbjct 240 ISALAALHGAWGVRVHDVRASVDAVKVVGAW 270 >gi|296166674|ref|ZP_06849099.1| dihydropteroate synthase [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295897939|gb|EFG77520.1| dihydropteroate synthase [Mycobacterium parascrofulaceum ATCC BAA-614] Length=277 Score = 383 bits (983), Expect = 2e-104, Method: Compositional matrix adjust. Identities = 209/262 (80%), Positives = 232/262 (89%), Gaps = 0/262 (0%) Query 9 MGVLNVTDDSFSDGGCYLDLDDAVKHGLAMAAAGAGIVDVGGESSRPGATRVDPAVETSR 68 MGVLNVTDDSFSDGG YLD +AV HGLA+AAAGA I+DVGGES+RPGATR+D VETSR Sbjct 1 MGVLNVTDDSFSDGGRYLDTSNAVAHGLALAAAGADIIDVGGESTRPGATRIDSRVETSR 60 Query 69 VIPVVKELAAQGITVSIDTMRADVARAALQNGAQMVNDVSGGRADPAMGPLLAEADVPWV 128 V+PVVKELAA+GITVSIDTM ADVARAALQNGA++VNDVSGGRADPAM PL+A+A VPWV Sbjct 61 VLPVVKELAAEGITVSIDTMHADVARAALQNGARIVNDVSGGRADPAMAPLMADAGVPWV 120 Query 129 LMHWRAVSADTPHVPVRYGNVVAEVRADLLASVADAVAAGVDPARLVLDPGLGFAKTAQH 188 LMHWR+V+AD PH Y +VVAEVRA+LLASV AV AGVDPA+LV+DPGLGFAKT H Sbjct 121 LMHWRSVAADRPHAAPHYVDVVAEVRAELLASVDAAVGAGVDPAKLVIDPGLGFAKTGHH 180 Query 189 NWAILHALPELVATGIPVLVGASRKRFLGALLAGPDGVMRPTDGRDTATAVISALAALHG 248 NWA+L ALPE VATGIPVL+GASRKRFLG LLAGPDG RP GR+TATAVISALAAL+G Sbjct 181 NWALLRALPEFVATGIPVLLGASRKRFLGTLLAGPDGSPRPPGGRETATAVISALAALYG 240 Query 249 AWGVRVHDVRASVDAIKVVEAW 270 AWGVRVHDVRA+ DA+KVV AW Sbjct 241 AWGVRVHDVRATADALKVVGAW 262 >gi|145222010|ref|YP_001132688.1| dihydropteroate synthase [Mycobacterium gilvum PYR-GCK] gi|145214496|gb|ABP43900.1| Dihydropteroate synthase [Mycobacterium gilvum PYR-GCK] Length=270 Score = 374 bits (961), Expect = 6e-102, Method: Compositional matrix adjust. Identities = 194/267 (73%), Positives = 220/267 (83%), Gaps = 0/267 (0%) Query 6 VQVMGVLNVTDDSFSDGGCYLDLDDAVKHGLAMAAAGAGIVDVGGESSRPGATRVDPAVE 65 +QVMGV+NVTDDSFSDGG +LD D AV HG+ + A GA IVDVGGES+RPGATRVDP VE Sbjct 1 MQVMGVVNVTDDSFSDGGLFLDRDRAVAHGVELVAQGAAIVDVGGESTRPGATRVDPEVE 60 Query 66 TSRVIPVVKELAAQGITVSIDTMRADVARAALQNGAQMVNDVSGGRADPAMGPLLAEADV 125 SR++PVVKELA QGITVSIDTM A VA AAL NGA++VNDVSGGRADP M ++A+A V Sbjct 61 ISRILPVVKELAQQGITVSIDTMHAAVAHAALDNGAKIVNDVSGGRADPDMVRVVADAGV 120 Query 126 PWVLMHWRAVSADTPHVPVRYGNVVAEVRADLLASVADAVAAGVDPARLVLDPGLGFAKT 185 PW+LMHWR+V D PH YG+VVAEVR +LL+ V AVAAGV P +L++DPGLGFAKT Sbjct 121 PWILMHWRSVDGDNPHEVPAYGDVVAEVRDELLSGVDAAVAAGVHPDKLIIDPGLGFAKT 180 Query 186 AQHNWAILHALPELVATGIPVLVGASRKRFLGALLAGPDGVMRPTDGRDTATAVISALAA 245 QHNWA+LHALP+ V+TGIPVLVGASRKRFLG LLA PDG RP GR+TATAVISALA Sbjct 181 GQHNWALLHALPDFVSTGIPVLVGASRKRFLGTLLAAPDGEPRPPAGRETATAVISALAG 240 Query 246 LHGAWGVRVHDVRASVDAIKVVEAWMG 272 H WGVRVHDVRASVDA+ VV AW G Sbjct 241 WHDVWGVRVHDVRASVDALAVVAAWRG 267 >gi|333992537|ref|YP_004525151.1| dihydropteroate synthase 1 FolP1 [Mycobacterium sp. JDM601] gi|333488505|gb|AEF37897.1| dihydropteroate synthase 1 FolP1 [Mycobacterium sp. JDM601] Length=282 Score = 374 bits (960), Expect = 1e-101, Method: Compositional matrix adjust. Identities = 198/273 (73%), Positives = 220/273 (81%), Gaps = 0/273 (0%) Query 1 VSPAPVQVMGVLNVTDDSFSDGGCYLDLDDAVKHGLAMAAAGAGIVDVGGESSRPGATRV 60 ++P QV+GV+NVT DSFSDGG YL+ D AV HGL + A GA I+DVGGES+RPGA R Sbjct 1 MNPTCAQVVGVVNVTADSFSDGGRYLNADRAVAHGLELVAEGAAIIDVGGESTRPGAVRA 60 Query 61 DPAVETSRVIPVVKELAAQGITVSIDTMRADVARAALQNGAQMVNDVSGGRADPAMGPLL 120 DP E RV+PVV+ELAAQGITVSIDTM A VARAAL GA++VNDVSGGRADPAM PLL Sbjct 61 DPRAEAQRVVPVVRELAAQGITVSIDTMNAAVARAALDCGAEIVNDVSGGRADPAMAPLL 120 Query 121 AEADVPWVLMHWRAVSADTPHVPVRYGNVVAEVRADLLASVADAVAAGVDPARLVLDPGL 180 A + WVLMHWR V PH Y +VVAEVRADLLASV AVA GVDPA+L++DPGL Sbjct 121 AASGAGWVLMHWRPVDPGHPHRVPGYRDVVAEVRADLLASVDAAVADGVDPAKLIIDPGL 180 Query 181 GFAKTAQHNWAILHALPELVATGIPVLVGASRKRFLGALLAGPDGVMRPTDGRDTATAVI 240 GFAKTAQHNW +L ALPELV GIPVLVGASRKRFLG LLAG DG RP D R+TATAVI Sbjct 181 GFAKTAQHNWTLLKALPELVGIGIPVLVGASRKRFLGTLLAGADGAPRPPDERETATAVI 240 Query 241 SALAALHGAWGVRVHDVRASVDAIKVVEAWMGA 273 SALA LHGAWGVRVHDVRASVDA++VV+AW A Sbjct 241 SALAGLHGAWGVRVHDVRASVDALRVVDAWTAA 273 >gi|315446250|ref|YP_004079129.1| dihydropteroate synthase [Mycobacterium sp. Spyr1] gi|315264553|gb|ADU01295.1| Dihydropteroate synthase [Mycobacterium sp. Spyr1] Length=274 Score = 373 bits (958), Expect = 2e-101, Method: Compositional matrix adjust. Identities = 193/267 (73%), Positives = 220/267 (83%), Gaps = 0/267 (0%) Query 6 VQVMGVLNVTDDSFSDGGCYLDLDDAVKHGLAMAAAGAGIVDVGGESSRPGATRVDPAVE 65 VQVMGV+NVTDDSFSDGG +LD D AV HG+ + A GA I+DVGGES+RPGATRVDP VE Sbjct 5 VQVMGVVNVTDDSFSDGGLFLDRDRAVAHGVELVAQGAAIIDVGGESTRPGATRVDPEVE 64 Query 66 TSRVIPVVKELAAQGITVSIDTMRADVARAALQNGAQMVNDVSGGRADPAMGPLLAEADV 125 SR++PVVKELA QGITVSIDTM A VA AAL +GA++VNDVSGGRADP M ++A+A V Sbjct 65 ISRILPVVKELAQQGITVSIDTMHAAVAHAALDSGAKIVNDVSGGRADPDMVRVVADAGV 124 Query 126 PWVLMHWRAVSADTPHVPVRYGNVVAEVRADLLASVADAVAAGVDPARLVLDPGLGFAKT 185 PW+LMHWR+V D PH YG+VVAEVR +LL+ V AVAAGV P +L++DPGLGFAKT Sbjct 125 PWILMHWRSVDGDNPHEVPAYGDVVAEVRDELLSGVDAAVAAGVHPDKLIIDPGLGFAKT 184 Query 186 AQHNWAILHALPELVATGIPVLVGASRKRFLGALLAGPDGVMRPTDGRDTATAVISALAA 245 QHNWA+LHALP+ V+TGIPVLVGASRKRFLG LLA PDG RP GR+TATAVISALA Sbjct 185 GQHNWALLHALPDFVSTGIPVLVGASRKRFLGTLLAAPDGEPRPPAGRETATAVISALAG 244 Query 246 LHGAWGVRVHDVRASVDAIKVVEAWMG 272 H WGVRVHDVRASVDA+ VV AW G Sbjct 245 WHDVWGVRVHDVRASVDALAVVAAWRG 271 >gi|120406318|ref|YP_956147.1| dihydropteroate synthase [Mycobacterium vanbaalenii PYR-1] gi|119959136|gb|ABM16141.1| dihydropteroate synthase [Mycobacterium vanbaalenii PYR-1] Length=268 Score = 370 bits (950), Expect = 1e-100, Method: Compositional matrix adjust. Identities = 190/263 (73%), Positives = 218/263 (83%), Gaps = 0/263 (0%) Query 9 MGVLNVTDDSFSDGGCYLDLDDAVKHGLAMAAAGAGIVDVGGESSRPGATRVDPAVETSR 68 MGV+NVTDDSFSDGG +LD D AV HG+ + GA IVDVGGES+RPGATR+DPAVE+SR Sbjct 1 MGVVNVTDDSFSDGGLFLDRDRAVIHGVELVRQGAAIVDVGGESTRPGATRIDPAVESSR 60 Query 69 VIPVVKELAAQGITVSIDTMRADVARAALQNGAQMVNDVSGGRADPAMGPLLAEADVPWV 128 ++PVVKELA GITVSIDTM A VAR AL++GAQ+VNDVSGGRADP M ++A+A VPWV Sbjct 61 ILPVVKELAQLGITVSIDTMHAAVARVALEHGAQIVNDVSGGRADPDMARVVADAGVPWV 120 Query 129 LMHWRAVSADTPHVPVRYGNVVAEVRADLLASVADAVAAGVDPARLVLDPGLGFAKTAQH 188 LMHWR+V +D PH YG+VV VR +L+A V AV AGVDPA+L++DPGLGFAKTAQH Sbjct 121 LMHWRSVGSDRPHEVPPYGDVVTAVRDELMAGVDAAVDAGVDPAKLIIDPGLGFAKTAQH 180 Query 189 NWAILHALPELVATGIPVLVGASRKRFLGALLAGPDGVMRPTDGRDTATAVISALAALHG 248 NWA+LHALPE V TGIPVLVGASRKRFLG LLA PDG +RP GR+TATAV+SALA H Sbjct 181 NWALLHALPEFVTTGIPVLVGASRKRFLGELLASPDGELRPPAGRETATAVVSALAGWHH 240 Query 249 AWGVRVHDVRASVDAIKVVEAWM 271 WGVRVHDVRASVDA+ VV AW Sbjct 241 VWGVRVHDVRASVDALAVVAAWQ 263 >gi|226363735|ref|YP_002781517.1| dihydropteroate synthase [Rhodococcus opacus B4] gi|226242224|dbj|BAH52572.1| dihydropteroate synthase [Rhodococcus opacus B4] Length=285 Score = 322 bits (825), Expect = 4e-86, Method: Compositional matrix adjust. Identities = 172/271 (64%), Positives = 203/271 (75%), Gaps = 3/271 (1%) Query 2 SPAPVQVMGVLNVTDDSFSDGGCYLDLDDAVKHGLAMAAAGAGIVDVGGESSRPGATRVD 61 SP VMG+LNVT DSFSDGG +LD D A++ GLA+ G IVDVGGES+RPGA RVD Sbjct 8 SPGRTVVMGILNVTTDSFSDGGRFLDRDAALERGLALNRLGVDIVDVGGESTRPGAARVD 67 Query 62 PAVETSRVIPVVKELAAQGITVSIDTMRADVARAALQNGAQMVNDVSGGRADPAMGPLLA 121 P VE RV PV+ +L A+GI VS+DTMRA VA AA++ GA ++NDV+GGRAD AM ++A Sbjct 68 PDVEAGRVAPVIADLVAEGICVSVDTMRASVAEAAIEAGASIINDVAGGRADAAMASVVA 127 Query 122 EADVPWVLMHWRAVSADTPH--VPVRYGNVVAEVRADLLASVADAVAAGVDPARLVLDPG 179 +A VPW+LMHWR+ + D H Y +VV EVR +L+ V AV AGVDP LVLDPG Sbjct 128 DAGVPWILMHWRS-AGDYVHRGAADHYDDVVREVRDELMTQVDLAVKAGVDPGSLVLDPG 186 Query 180 LGFAKTAQHNWAILHALPELVATGIPVLVGASRKRFLGALLAGPDGVMRPTDGRDTATAV 239 LGFAK + HNWA+L ALPE G PVLVGASRKRFLG+LLA DG RP GR+TATAV Sbjct 187 LGFAKNSDHNWALLKALPEFNELGFPVLVGASRKRFLGSLLADADGEPRPPAGRETATAV 246 Query 240 ISALAALHGAWGVRVHDVRASVDAIKVVEAW 270 +SALAA HGAWGVRVHD +AS+DAI V EAW Sbjct 247 VSALAATHGAWGVRVHDAQASLDAIAVAEAW 277 >gi|169627639|ref|YP_001701288.1| dihydropteroate synthase [Mycobacterium abscessus ATCC 19977] gi|169239606|emb|CAM60634.1| Dihydropteroate synthase (FolP) [Mycobacterium abscessus] Length=350 Score = 321 bits (823), Expect = 7e-86, Method: Compositional matrix adjust. Identities = 169/271 (63%), Positives = 208/271 (77%), Gaps = 4/271 (1%) Query 2 SPAPVQVMGVLNVTDDSFSDGGCYLDLDDAVKHGLAMAAAGAGIVDVGGESSRPGATRVD 61 +PA ++GV+NVTDDSFSDGG ++ DAV HGLA+A+AGA I+DVGG+S+RPGA + Sbjct 8 TPALTHILGVVNVTDDSFSDGGRFVRQSDAVAHGLALASAGADIIDVGGQSTRPGAAPIR 67 Query 62 PAVETSRVIPVVKELAAQGITVSIDTMRADVARAALQNGAQMVNDVSGGRADPAMGPLLA 121 +E RVIPV+KELA+ GI +S+DTMRA+VA AA+ GA MVNDVSGGR+DP M L+A Sbjct 68 QKIEMQRVIPVIKELASHGINISVDTMRAEVAAAAIDAGANMVNDVSGGRSDPEMAQLIA 127 Query 122 EADVPWVLMHWRAVSADTPHVPV--RYGNVVAEVRADLLASVADAVAAGVDPARLVLDPG 179 + VPW+LMHWR S D H P Y +VVA+V +L+ SVA AV AGV P +L+LDPG Sbjct 128 QRGVPWILMHWR--SKDFIHTPATRNYRDVVADVSRELMESVAVAVNAGVSPDKLILDPG 185 Query 180 LGFAKTAQHNWAILHALPELVATGIPVLVGASRKRFLGALLAGPDGVMRPTDGRDTATAV 239 LGFAKTA HNW +L A+P+L G P+L+GASRKRFLG+LL GV RP DGR+TATAV Sbjct 186 LGFAKTAHHNWLLLQAIPDLQELGYPILIGASRKRFLGSLLTDLKGVERPPDGRETATAV 245 Query 240 ISALAALHGAWGVRVHDVRASVDAIKVVEAW 270 I+AL ALH WGVRVHDV AS+DA+KVV AW Sbjct 246 ITALGALHEVWGVRVHDVTASMDALKVVRAW 276 >gi|312138054|ref|YP_004005390.1| dihydropteroate synthase folp1 [Rhodococcus equi 103S] gi|325675045|ref|ZP_08154732.1| dihydropteroate synthase [Rhodococcus equi ATCC 33707] gi|311887393|emb|CBH46705.1| dihydropteroate synthase FolP1 [Rhodococcus equi 103S] gi|325554631|gb|EGD24306.1| dihydropteroate synthase [Rhodococcus equi ATCC 33707] Length=281 Score = 318 bits (815), Expect = 6e-85, Method: Compositional matrix adjust. Identities = 169/265 (64%), Positives = 200/265 (76%), Gaps = 3/265 (1%) Query 8 VMGVLNVTDDSFSDGGCYLDLDDAVKHGLAMAAAGAGIVDVGGESSRPGATRVDPAVETS 67 VMGVLNVT DSFSDGG +LD D AV HG+ + G IVDVGGES+RPGA RVDP +E Sbjct 12 VMGVLNVTADSFSDGGQFLDRDAAVAHGVHLHRLGVDIVDVGGESTRPGAARVDPKIEAE 71 Query 68 RVIPVVKELAAQGITVSIDTMRADVARAALQNGAQMVNDVSGGRADPAMGPLLAEADVPW 127 RV PVV L +G+TVS+DTMRA VA+AA++ G +VNDVSGGRAD M ++A+A VPW Sbjct 72 RVAPVVAALVDEGVTVSVDTMRASVAQAAIEAGVTIVNDVSGGRADSDMARVVADAGVPW 131 Query 128 VLMHWRAVSADTPHV--PVRYGNVVAEVRADLLASVADAVAAGVDPARLVLDPGLGFAKT 185 VLMHWR + + H Y +VV +VR +L+ V A+AAGVDP+ LVLDPGLGF K Sbjct 132 VLMHWRP-AGEFVHAGGSTHYDDVVRDVRDELMVQVDAAIAAGVDPSALVLDPGLGFVKD 190 Query 186 AQHNWAILHALPELVATGIPVLVGASRKRFLGALLAGPDGVMRPTDGRDTATAVISALAA 245 HNW +LHALPE V G PVL+GASRKRFLG+LLA DGV+RP GR+TATAVISALAA Sbjct 191 PDHNWQLLHALPEFVELGFPVLIGASRKRFLGSLLADADGVVRPPSGRETATAVISALAA 250 Query 246 LHGAWGVRVHDVRASVDAIKVVEAW 270 +HGAWGVRVHD +AS+DAI V AW Sbjct 251 MHGAWGVRVHDAQASLDAIAVASAW 275 >gi|54022364|ref|YP_116606.1| putative dihydropteroate synthase [Nocardia farcinica IFM 10152] gi|54013872|dbj|BAD55242.1| putative dihydropteroate synthase [Nocardia farcinica IFM 10152] Length=296 Score = 318 bits (815), Expect = 6e-85, Method: Compositional matrix adjust. Identities = 177/269 (66%), Positives = 209/269 (78%), Gaps = 4/269 (1%) Query 8 VMGVLNVTDDSFSDGGCYLDLDDAVKHGLAMAAAGAGIVDVGGESSRPGATRVDPAVETS 67 VMGV+NVT DSFSDGG YLD D A+ HG+ + AGA I+DVGGES+RPGA RVDPA E + Sbjct 21 VMGVVNVTSDSFSDGGRYLDPDRAIAHGVELYEAGADIIDVGGESTRPGAVRVDPATEAA 80 Query 68 RVIPVVKELAAQGITVSIDTMRADVARAALQNGAQMVNDVSGGRADPAMGPLLAEADVPW 127 RV PV++ L A G+ S+DTMRA VA AAL G ++NDVSGGRAD M ++AEADVPW Sbjct 81 RVTPVIQGLVAAGVPTSVDTMRAAVAEAALAAGVSVINDVSGGRADADMVKVVAEADVPW 140 Query 128 VLMHWRAVSADTPHV-PV-RYGNVVAEVRADLLASVADAVAAGVDPARLVLDPGLGFAKT 185 +LMHWRA +AD H P Y +VVAEVR +L A V AV +GVDP RL+LDPGLGFAK Sbjct 141 ILMHWRA-AADYRHTGPADHYEDVVAEVRTELDAQVELAVRSGVDPGRLILDPGLGFAKN 199 Query 186 AQHNWAILHALPELVATGIPVLVGASRKRFLGALLAGPDGVMRPTDGRDTATAVISALAA 245 A HNWA+L ALPE V G+PVL+GASRKRFLGALLA +G RP DGR+ ATA +SALAA Sbjct 200 AAHNWALLAALPEFVEAGLPVLIGASRKRFLGALLADANG-PRPPDGREVATATVSALAA 258 Query 246 LHGAWGVRVHDVRASVDAIKVVEAWMGAE 274 L+GAWGVRVHDVR+S+DAI VV+AW A+ Sbjct 259 LYGAWGVRVHDVRSSLDAIAVVDAWQRAQ 287 >gi|111021381|ref|YP_704353.1| dihydropteroate synthase [Rhodococcus jostii RHA1] gi|110820911|gb|ABG96195.1| dihydropteroate synthase [Rhodococcus jostii RHA1] Length=285 Score = 317 bits (812), Expect = 1e-84, Method: Compositional matrix adjust. Identities = 170/271 (63%), Positives = 199/271 (74%), Gaps = 3/271 (1%) Query 2 SPAPVQVMGVLNVTDDSFSDGGCYLDLDDAVKHGLAMAAAGAGIVDVGGESSRPGATRVD 61 SP VMGVLNVT DSFSDGG +LD D A+ GL + G IVDVGGES+RPGA RVD Sbjct 8 SPGRTVVMGVLNVTTDSFSDGGRFLDRDAALARGLELKRLGVDIVDVGGESTRPGAARVD 67 Query 62 PAVETSRVIPVVKELAAQGITVSIDTMRADVARAALQNGAQMVNDVSGGRADPAMGPLLA 121 P VE RV PV+ +L +GI VS+DTMRA VA AA++ GA ++NDV+GGRAD AM ++A Sbjct 68 PDVEAGRVAPVIADLVGEGICVSVDTMRASVAEAAIEAGASIINDVAGGRADAAMASVVA 127 Query 122 EADVPWVLMHWRAVSADTPH--VPVRYGNVVAEVRADLLASVADAVAAGVDPARLVLDPG 179 +A VPW+LMHWR+ +AD H Y +VV EVR +L+ V AV AGVDP LVLDPG Sbjct 128 DAGVPWILMHWRS-AADYVHRGTADHYDDVVREVRDELMTQVDLAVKAGVDPGSLVLDPG 186 Query 180 LGFAKTAQHNWAILHALPELVATGIPVLVGASRKRFLGALLAGPDGVMRPTDGRDTATAV 239 LGFAK A HNWA+L ALPE G PVL+GASRKRFLG+LLA DG RP GR+ ATAV Sbjct 187 LGFAKNADHNWALLKALPEFNELGFPVLIGASRKRFLGSLLADADGEPRPPAGREIATAV 246 Query 240 ISALAALHGAWGVRVHDVRASVDAIKVVEAW 270 +SALAA HGAWGVRVHD + S+DAI V EAW Sbjct 247 VSALAATHGAWGVRVHDAQGSLDAIAVAEAW 277 >gi|298527086|ref|ZP_07014495.1| dihydropteroate synthase [Mycobacterium tuberculosis 94_M4241A] gi|298496880|gb|EFI32174.1| dihydropteroate synthase [Mycobacterium tuberculosis 94_M4241A] Length=168 Score = 315 bits (807), Expect = 4e-84, Method: Compositional matrix adjust. Identities = 162/167 (98%), Positives = 164/167 (99%), Gaps = 0/167 (0%) Query 114 PAMGPLLAEADVPWVLMHWRAVSADTPHVPVRYGNVVAEVRADLLASVADAVAAGVDPAR 173 P+ +LAEADVPWVLMHWRAVSADTPHVPVRYGNVVAEVRADLLASVADAVAAGVDPAR Sbjct 2 PSWCRMLAEADVPWVLMHWRAVSADTPHVPVRYGNVVAEVRADLLASVADAVAAGVDPAR 61 Query 174 LVLDPGLGFAKTAQHNWAILHALPELVATGIPVLVGASRKRFLGALLAGPDGVMRPTDGR 233 LVLDPGLGFAKTAQHNWAILHALPELVATGIPVLVGASRKRFLGALLAGPDGVMRPTDGR Sbjct 62 LVLDPGLGFAKTAQHNWAILHALPELVATGIPVLVGASRKRFLGALLAGPDGVMRPTDGR 121 Query 234 DTATAVISALAALHGAWGVRVHDVRASVDAIKVVEAWMGAERIERDG 280 DTATAVISALAALHGAWGVRVHDVRASVDAIKVVEAWMGAERIERDG Sbjct 122 DTATAVISALAALHGAWGVRVHDVRASVDAIKVVEAWMGAERIERDG 168 >gi|226304116|ref|YP_002764074.1| dihydropteroate synthase [Rhodococcus erythropolis PR4] gi|226183231|dbj|BAH31335.1| dihydropteroate synthase [Rhodococcus erythropolis PR4] Length=289 Score = 309 bits (792), Expect = 2e-82, Method: Compositional matrix adjust. Identities = 174/276 (64%), Positives = 211/276 (77%), Gaps = 4/276 (1%) Query 3 PAPVQVMGVLNVTDDSFSDGGCYLDLDDAVKHGLAMAAAGAGIVDVGGESSRPGATRVDP 62 PA + VMG+LNVT DSFSDGG +LD D A+ GL + G IVDVGGES+RPGATRVDP Sbjct 14 PARMVVMGILNVTADSFSDGGQFLDRDAAIARGLELQRIGVDIVDVGGESTRPGATRVDP 73 Query 63 AVETSRVIPVVKELAAQGITVSIDTMRADVARAALQNGAQMVNDVSGGRADPAMGPLLAE 122 +E R+ PV++EL A GI VS+DTMRA VA AA++ GA +VNDVSGGRADP M ++A+ Sbjct 74 KLEADRIAPVIEELVAAGIRVSVDTMRASVAAAAIEAGAGIVNDVSGGRADPDMASVVAD 133 Query 123 ADVPWVLMHWRAVSADTPH--VPVRYGNVVAEVRADLLASVADAVAAGVDPARLVLDPGL 180 A VPW+LMHWR+ + D H +Y +VV +VR +LL+ V A+ AGVD + ++LDPGL Sbjct 134 AGVPWILMHWRS-AGDYVHRGSADQYDHVVRDVRDELLSQVDLALKAGVDSSSIILDPGL 192 Query 181 GFAKTAQHNWAILHALPELVATGIPVLVGASRKRFLGALLAGPDGVMRPTDGRDTATAVI 240 GFAK A HNWA+L ALPE ATG PVLVGASRKRFLG+LL+ PDG RP GR+TATAV+ Sbjct 193 GFAKNADHNWALLRALPEFNATGFPVLVGASRKRFLGSLLSDPDGNPRPPGGRETATAVV 252 Query 241 SALAALHGAWGVRVHDVRASVDAIKVVEAW-MGAER 275 SALAA GAWGVRVHD +AS+DAI VV+AW G ER Sbjct 253 SALAAREGAWGVRVHDAQASLDAIAVVDAWNRGRER 288 >gi|229494353|ref|ZP_04388116.1| dihydropteroate synthase [Rhodococcus erythropolis SK121] gi|229318715|gb|EEN84573.1| dihydropteroate synthase [Rhodococcus erythropolis SK121] Length=289 Score = 309 bits (791), Expect = 4e-82, Method: Compositional matrix adjust. Identities = 174/276 (64%), Positives = 210/276 (77%), Gaps = 4/276 (1%) Query 3 PAPVQVMGVLNVTDDSFSDGGCYLDLDDAVKHGLAMAAAGAGIVDVGGESSRPGATRVDP 62 PA + VMG+LNVT DSFSDGG +LD D A+ GL + G IVDVGGES+RPGATRVDP Sbjct 14 PARMVVMGILNVTADSFSDGGQFLDRDAAIARGLELQRIGVDIVDVGGESTRPGATRVDP 73 Query 63 AVETSRVIPVVKELAAQGITVSIDTMRADVARAALQNGAQMVNDVSGGRADPAMGPLLAE 122 +E R+ PV++EL A GI VS+DTMRA VA AA++ GA +VNDVSGGRADP M ++A+ Sbjct 74 KLEADRIAPVIEELVAAGIRVSVDTMRASVAAAAIEAGAGIVNDVSGGRADPDMASVVAD 133 Query 123 ADVPWVLMHWRAVSADTPH--VPVRYGNVVAEVRADLLASVADAVAAGVDPARLVLDPGL 180 A VPW+LMHWR+ + D H Y +VV +VR +LL+ V A+ AGVD + ++LDPGL Sbjct 134 AGVPWILMHWRS-AGDYVHRGSADHYDDVVRDVRDELLSQVDLALKAGVDSSSIILDPGL 192 Query 181 GFAKTAQHNWAILHALPELVATGIPVLVGASRKRFLGALLAGPDGVMRPTDGRDTATAVI 240 GFAK A HNWA+L ALPE ATG PVLVGASRKRFLG+LL+ PDG RP GR+TATAV+ Sbjct 193 GFAKNADHNWALLRALPEFNATGFPVLVGASRKRFLGSLLSDPDGNPRPPGGRETATAVV 252 Query 241 SALAALHGAWGVRVHDVRASVDAIKVVEAW-MGAER 275 SALAA GAWGVRVHD +AS+DAI VV+AW G ER Sbjct 253 SALAAREGAWGVRVHDAQASLDAIAVVDAWNRGRER 288 >gi|326384085|ref|ZP_08205768.1| dihydropteroate synthase [Gordonia neofelifaecis NRRL B-59395] gi|326197245|gb|EGD54436.1| dihydropteroate synthase [Gordonia neofelifaecis NRRL B-59395] Length=300 Score = 306 bits (783), Expect = 3e-81, Method: Compositional matrix adjust. Identities = 179/273 (66%), Positives = 204/273 (75%), Gaps = 12/273 (4%) Query 8 VMGVLNVTDDSFSDGGCYLDLDDAVKHGLAMAAAGAGIVDVGGESSRPGATRVDPAVETS 67 VMGVLNVT DSFSDGG YL D AV HGL + AGA I+DVGGES+RPGA RVDPA E++ Sbjct 19 VMGVLNVTADSFSDGGRYLQRDRAVAHGLELRGAGADIIDVGGESTRPGAVRVDPATESA 78 Query 68 RVIPVVKELAAQGITVSIDTMRADVARAALQNGAQMVNDVSGGRADPAMGPLLAEADVPW 127 RV+PV++EL A G VS+DTMRA VA AL GA ++NDVSGGRADP MG +LA+A VPW Sbjct 79 RVVPVIRELVAAGARVSVDTMRAAVAADALAAGADLINDVSGGRADPDMGRVLADAGVPW 138 Query 128 VLMHWRAVSADTP----HVPVR------YGNVVAEVRADLLASVADAVAAGVDPARLVLD 177 +LMHWR D P H R Y +VVAEV +LL V AVAAGVDP ++VLD Sbjct 139 ILMHWRPAD-DAPGGDRHFTHRVDEAGGYRDVVAEVTGELLGQVDAAVAAGVDPDQIVLD 197 Query 178 PGLGFAKTAQHNWAILHALPELVATGIPVLVGASRKRFLGALLAGPDGVMRPTDGRDTAT 237 PGLGFAKTA+HNWA+LHALP LV G PVL+GASRKRFLG+LL DGV RP GR+ AT Sbjct 198 PGLGFAKTAEHNWALLHALPTLVGLGFPVLIGASRKRFLGSLLQ-RDGVDRPPAGREVAT 256 Query 238 AVISALAALHGAWGVRVHDVRASVDAIKVVEAW 270 A ISAL+A GAWGVRVHDV AS DAI+V AW Sbjct 257 AAISALSAAGGAWGVRVHDVAASRDAIEVALAW 289 >gi|289759767|ref|ZP_06519145.1| dihydropteroate synthase 1 folp [Mycobacterium tuberculosis T85] gi|289715331|gb|EFD79343.1| dihydropteroate synthase 1 folp [Mycobacterium tuberculosis T85] Length=160 Score = 305 bits (781), Expect = 5e-81, Method: Compositional matrix adjust. Identities = 156/156 (100%), Positives = 156/156 (100%), Gaps = 0/156 (0%) Query 125 VPWVLMHWRAVSADTPHVPVRYGNVVAEVRADLLASVADAVAAGVDPARLVLDPGLGFAK 184 VPWVLMHWRAVSADTPHVPVRYGNVVAEVRADLLASVADAVAAGVDPARLVLDPGLGFAK Sbjct 5 VPWVLMHWRAVSADTPHVPVRYGNVVAEVRADLLASVADAVAAGVDPARLVLDPGLGFAK 64 Query 185 TAQHNWAILHALPELVATGIPVLVGASRKRFLGALLAGPDGVMRPTDGRDTATAVISALA 244 TAQHNWAILHALPELVATGIPVLVGASRKRFLGALLAGPDGVMRPTDGRDTATAVISALA Sbjct 65 TAQHNWAILHALPELVATGIPVLVGASRKRFLGALLAGPDGVMRPTDGRDTATAVISALA 124 Query 245 ALHGAWGVRVHDVRASVDAIKVVEAWMGAERIERDG 280 ALHGAWGVRVHDVRASVDAIKVVEAWMGAERIERDG Sbjct 125 ALHGAWGVRVHDVRASVDAIKVVEAWMGAERIERDG 160 >gi|289748122|ref|ZP_06507500.1| dihydropteroate synthase 1 folp [Mycobacterium tuberculosis T92] gi|289688709|gb|EFD56138.1| dihydropteroate synthase 1 folp [Mycobacterium tuberculosis T92] Length=179 Score = 304 bits (778), Expect = 1e-80, Method: Compositional matrix adjust. Identities = 166/175 (95%), Positives = 169/175 (97%), Gaps = 0/175 (0%) Query 1 VSPAPVQVMGVLNVTDDSFSDGGCYLDLDDAVKHGLAMAAAGAGIVDVGGESSRPGATRV 60 +SPAPVQVMGVLNVTDDSFSDGGCYLDLDDAVKHGLAMAAAGAGIVDVGGESSRPGATRV Sbjct 1 MSPAPVQVMGVLNVTDDSFSDGGCYLDLDDAVKHGLAMAAAGAGIVDVGGESSRPGATRV 60 Query 61 DPAVETSRVIPVVKELAAQGITVSIDTMRADVARAALQNGAQMVNDVSGGRADPAMGPLL 120 DPAVETSRVIPVVKELAAQGITVSIDTMRADVARAALQNGAQMVNDVSGGRADPAMGPLL Sbjct 61 DPAVETSRVIPVVKELAAQGITVSIDTMRADVARAALQNGAQMVNDVSGGRADPAMGPLL 120 Query 121 AEADVPWVLMHWRAVSADTPHVPVRYGNVVAEVRADLLASVADAVAAGVDPARLV 175 AEADVPWVLMHWRAVSADTPHVPVRYGNVVAEVR DLLASV D +AA VDPA + Sbjct 121 AEADVPWVLMHWRAVSADTPHVPVRYGNVVAEVRVDLLASVVDPMAASVDPACMC 175 >gi|343924376|ref|ZP_08763926.1| dihydropteroate synthase [Gordonia alkanivorans NBRC 16433] gi|343765708|dbj|GAA10852.1| dihydropteroate synthase [Gordonia alkanivorans NBRC 16433] Length=284 Score = 301 bits (772), Expect = 6e-80, Method: Compositional matrix adjust. Identities = 167/269 (63%), Positives = 197/269 (74%), Gaps = 8/269 (2%) Query 9 MGVLNVTDDSFSDGGCYLDLDDAVKHGLAMAAAGAGIVDVGGESSRPGATRVDPAVETSR 68 MGVLNVT DSFSDGG YLD D AV HGL + GA ++DVGGES+RPGA RVDP +E R Sbjct 1 MGVLNVTADSFSDGGRYLDTDAAVAHGLQLIEQGADLIDVGGESTRPGAIRVDPDLEAKR 60 Query 69 VIPVVKELAAQGITVSIDTMRADVARAALQNGAQMVNDVSGGRADPAMGPLLAEADVPWV 128 V PV+ LA+ G+ VS+DTMR++VA AA++ GA +VNDVSGGRAD M ++A+A +PW+ Sbjct 61 VAPVIAALASHGVVVSVDTMRSEVAAAAIEAGASIVNDVSGGRADADMARVVADARLPWI 120 Query 129 LMHWRAVSADTPHVPVR-------YGNVVAEVRADLLASVADAVAAGVDPARLVLDPGLG 181 LMHWR T Y +VVAEV +LLA V AV+AGVDP +L+LDPGLG Sbjct 121 LMHWRPAGESTDRRFTHRIGDVGGYRDVVAEVSGELLAQVDAAVSAGVDPDQLILDPGLG 180 Query 182 FAKTAQHNWAILHALPELVATGIPVLVGASRKRFLGALLAGPDGVMRPTDGRDTATAVIS 241 FAKTA+HNWA+LHALP + G PVLVGASRKRFLG LL G DGV RP GRD ATA IS Sbjct 181 FAKTAEHNWALLHALPTFIGLGFPVLVGASRKRFLGTLL-GRDGVDRPPAGRDIATASIS 239 Query 242 ALAALHGAWGVRVHDVRASVDAIKVVEAW 270 AL A GAWGVRVHDV ++ DA+ V EAW Sbjct 240 ALTAAAGAWGVRVHDVASTYDAVTVAEAW 268 >gi|333917991|ref|YP_004491572.1| dihydropteroate synthase [Amycolicicoccus subflavus DQS3-9A1] gi|333480212|gb|AEF38772.1| Dihydropteroate synthase [Amycolicicoccus subflavus DQS3-9A1] Length=292 Score = 293 bits (751), Expect = 1e-77, Method: Compositional matrix adjust. Identities = 160/273 (59%), Positives = 194/273 (72%), Gaps = 4/273 (1%) Query 2 SPAPVQVMGVLNVTDDSFSDGGCYLDLDDAVKHGLAMAAAGAGIVDVGGESSRPGATRVD 61 +P VMG++NVT DSFSDGG +LD + A+ GL + G +VD+GGES+RPGA RVD Sbjct 15 APGRCVVMGIVNVTGDSFSDGGQFLDPERAIARGLELRNLGVDVVDIGGESTRPGAVRVD 74 Query 62 PAVETSRVIPVVKELAAQGITVSIDTMRADVARAALQNGAQMVNDVSGGRADPAMGPLLA 121 PAVE RVIPV+ L + G+ VS+DTMRA VA A+ GA +VNDVSGG+ADP M ++A Sbjct 75 PAVEARRVIPVISALTSAGVAVSVDTMRATVAAEAITAGAAIVNDVSGGQADPDMAKVIA 134 Query 122 EADVPWVLMHWRAVSADTPHVPVR----YGNVVAEVRADLLASVADAVAAGVDPARLVLD 177 +A VPW+LMHWR+ Y ++V EV A+LL V AV AGVDP+ LVLD Sbjct 135 DAGVPWILMHWRSNGEYVHRADAGGRDGYRDIVKEVSAELLTQVDAAVRAGVDPSALVLD 194 Query 178 PGLGFAKTAQHNWAILHALPELVATGIPVLVGASRKRFLGALLAGPDGVMRPTDGRDTAT 237 PGLGFAKTA+ NWA+L ALP L G PVL+GASRKRFLG+LL+GPDG R RDTAT Sbjct 195 PGLGFAKTAEDNWALLQALPHLAGLGFPVLIGASRKRFLGSLLSGPDGTERAVLERDTAT 254 Query 238 AVISALAALHGAWGVRVHDVRASVDAIKVVEAW 270 A ISALA GAWGVRVHD R+++DAI V AW Sbjct 255 AAISALAVAGGAWGVRVHDARSTLDAIAVAHAW 287 >gi|262203870|ref|YP_003275078.1| dihydropteroate synthase [Gordonia bronchialis DSM 43247] gi|262087217|gb|ACY23185.1| dihydropteroate synthase [Gordonia bronchialis DSM 43247] Length=283 Score = 289 bits (740), Expect = 3e-76, Method: Compositional matrix adjust. Identities = 162/255 (64%), Positives = 191/255 (75%), Gaps = 7/255 (2%) Query 9 MGVLNVTDDSFSDGGCYLDLDDAVKHGLAMAAAGAGIVDVGGESSRPGATRVDPAVETSR 68 MGV+NVT DSFSDGG YLD AV+HGLA+ A GA ++DVGGES+RPGA RVDP +E +R Sbjct 1 MGVINVTADSFSDGGRYLDTAAAVEHGLALRAEGADLIDVGGESTRPGAIRVDPDLEAAR 60 Query 69 VIPVVKELAAQGITVSIDTMRADVARAALQNGAQMVNDVSGGRADPAMGPLLAEADVPWV 128 V PV+ L+ G +S+DTMRA VA AA+ GA +VNDVSGGRAD M ++A+A +PW+ Sbjct 61 VTPVISALSGHGARISVDTMRASVAAAAIDAGATVVNDVSGGRADADMAKVVADAGLPWI 120 Query 129 LMHWRAVSADTP-HVPVR------YGNVVAEVRADLLASVADAVAAGVDPARLVLDPGLG 181 LMHWR T H R Y +VVAEV +LLA V AV+AGVDP ++LDPGLG Sbjct 121 LMHWRPAGDSTDRHFTHRIGDVGGYRDVVAEVSGELLAQVDAAVSAGVDPDHIILDPGLG 180 Query 182 FAKTAQHNWAILHALPELVATGIPVLVGASRKRFLGALLAGPDGVMRPTDGRDTATAVIS 241 FAKTA+HNWA+LHALP LV G PVLVGASRKRFLG LLAG DG +RP RD ATA IS Sbjct 181 FAKTAEHNWALLHALPTLVGLGFPVLVGASRKRFLGTLLAGDDGTVRPPQERDVATASIS 240 Query 242 ALAALHGAWGVRVHD 256 ALAA++GAWGVRVHD Sbjct 241 ALAAMNGAWGVRVHD 255 >gi|325000125|ref|ZP_08121237.1| 7,8-dihydropteroate synthase (partial match) [Pseudonocardia sp. P1] Length=292 Score = 288 bits (738), Expect = 5e-76, Method: Compositional matrix adjust. Identities = 168/269 (63%), Positives = 197/269 (74%), Gaps = 2/269 (0%) Query 8 VMGVLNVTDDSFSDGGCYLDLDDAVKHGLAMAAAGAGIVDVGGESSRPGATRVDPAVETS 67 VMG+LNVT DSFSDGG YLD A+ HG+AM AGA +VDVGGES+RPGA RVD E Sbjct 16 VMGILNVTPDSFSDGGRYLDRSHAIAHGVAMRDAGADLVDVGGESTRPGAERVDAVTERD 75 Query 68 RVIPVVKELAAQGITVSIDTMRADVARAALQNGAQMVNDVSGGRADPAMGPLLAEADVPW 127 RV+PVV+EL G+ VS+DT R++VA A + GA MVNDVSGG ADP M ++AE VPW Sbjct 76 RVVPVVRELTGAGVRVSVDTTRSEVAAACVDAGAVMVNDVSGGLADPRMAAVVAETRVPW 135 Query 128 VLMHWRAVSADTPHVPVRYGNVVAEVRADLLASVADAVAAGVDPARLVLDPGLGFAKTAQ 187 VLMHWR SA + Y +V+ EVRA+L+A V AV AGVDP R++LDPGLGFAKTA Sbjct 136 VLMHWRGHSAGMQQL-AGYEDVIGEVRAELVARVDHAVMAGVDPDRILLDPGLGFAKTAA 194 Query 188 HNWAILHALPELVATGIPVLVGASRKRFLGALLAGPDGVMRPTDGRDTATAVISALAALH 247 HNWA+L + L+ G PVLVGASRKRFLG LLA DG RP GRDTATA ISALAA Sbjct 195 HNWALLRRIDVLIDLGFPVLVGASRKRFLGDLLATGDGTPRPPAGRDTATAAISALAANA 254 Query 248 GAWGVRVHDVRASVDAIKVVEAW-MGAER 275 GAWGVRVHDV +++DA+ V A +GA R Sbjct 255 GAWGVRVHDVESTMDAVAVAAACRLGASR 283 >gi|284989215|ref|YP_003407769.1| dihydropteroate synthase [Geodermatophilus obscurus DSM 43160] gi|284062460|gb|ADB73398.1| dihydropteroate synthase [Geodermatophilus obscurus DSM 43160] Length=286 Score = 288 bits (736), Expect = 8e-76, Method: Compositional matrix adjust. Identities = 166/269 (62%), Positives = 193/269 (72%), Gaps = 1/269 (0%) Query 1 VSPAPVQVMGVLNVTDDSFSDGGCYLDLDDAVKHGLAMAAAGAGIVDVGGESSRPGATRV 60 + P VMGVLNVT DSFSDGGC+ D AV HGLAM AAGA VDVGGES+RPGA RV Sbjct 7 LRPGHCVVMGVLNVTPDSFSDGGCFADAGAAVAHGLAMHAAGADYVDVGGESTRPGADRV 66 Query 61 DPAVETSRVIPVVKELAAQGITVSIDTMRADVARAALQNGAQMVNDVSGGRADPAMGPLL 120 D A E RV+PV++ELAA G+ S+DT RA+VA AAL GA +VNDVSGG AD M L+ Sbjct 67 DAAEECGRVVPVIRELAAAGVRPSVDTTRAEVAEAALAAGAVLVNDVSGGLADKNMAELV 126 Query 121 AEADVPWVLMHWRAVSADTPHVPVRYGNVVAEVRADLLASVADAVAAGVDPARLVLDPGL 180 AEA VPWVLMHWR S + + +YG+VV EV A+L A V D VAAGV P +LVLDPGL Sbjct 127 AEAGVPWVLMHWRGHSREM-YAAAQYGDVVTEVCAELTARVEDVVAAGVAPEQLVLDPGL 185 Query 181 GFAKTAQHNWAILHALPELVATGIPVLVGASRKRFLGALLAGPDGVMRPTDGRDTATAVI 240 GFAK ++HNW +L L +V G+PVLVGASRK FLG LLA PD +RP + RD AT Sbjct 186 GFAKRSEHNWRLLAGLDRIVGLGLPVLVGASRKSFLGRLLAAPDDTLRPAEQRDAATLAT 245 Query 241 SALAALHGAWGVRVHDVRASVDAIKVVEA 269 + LAA GAWGVRVHD AS DA++ V A Sbjct 246 TVLAAEAGAWGVRVHDAAASADAVRTVAA 274 >gi|302530787|ref|ZP_07283129.1| dihydropteroate synthase [Streptomyces sp. AA4] gi|302439682|gb|EFL11498.1| dihydropteroate synthase [Streptomyces sp. AA4] Length=278 Score = 279 bits (713), Expect = 3e-73, Method: Compositional matrix adjust. Identities = 167/269 (63%), Positives = 203/269 (76%), Gaps = 1/269 (0%) Query 3 PAPVQVMGVLNVTDDSFSDGGCYLDLDDAVKHGLAMAAAGAGIVDVGGESSRPGATRVDP 62 P VMGVLNVT DSFSDGG YLDLD A++H M A GA ++DVGGES+RPGA+RVD Sbjct 5 PGRCAVMGVLNVTPDSFSDGGRYLDLDQALEHAREMWARGADLIDVGGESTRPGASRVDA 64 Query 63 AVETSRVIPVVKELAAQGITVSIDTMRADVARAALQNGAQMVNDVSGGRADPAMGPLLAE 122 E +RV+PV+++LA++G+ +S+DT RA VA AA+ GA+++NDVSGG ADPAMG + AE Sbjct 65 ETEAARVLPVIRQLASEGVVLSVDTTRAAVAEAAVAAGAKVINDVSGGLADPAMGRVAAE 124 Query 123 ADVPWVLMHWRAVSADTPHVPVRYGNVVAEVRADLLASVADAVAAGVDPARLVLDPGLGF 182 PWVLMHWR S D + Y +VVAEVR +LL V +A+AAGV + +VLDPGLGF Sbjct 125 TKAPWVLMHWRGHSKDMNALAT-YTDVVAEVRGELLQRVDEAIAAGVAESEIVLDPGLGF 183 Query 183 AKTAQHNWAILHALPELVATGIPVLVGASRKRFLGALLAGPDGVMRPTDGRDTATAVISA 242 AK A+H+WA+LH L L+ G PVLVGASRKRFLG LLAG DGV RP DGR+ ATA ISA Sbjct 184 AKHAEHDWALLHGLDSLLQLGFPVLVGASRKRFLGRLLAGKDGVPRPPDGREVATASISA 243 Query 243 LAALHGAWGVRVHDVRASVDAIKVVEAWM 271 LAA GAWGVRVH+V AS+DA+ V AW Sbjct 244 LAAAAGAWGVRVHEVGASLDAVAVAAAWQ 272 >gi|302870316|ref|YP_003838953.1| dihydropteroate synthase [Micromonospora aurantiaca ATCC 27029] gi|302573175|gb|ADL49377.1| dihydropteroate synthase [Micromonospora aurantiaca ATCC 27029] Length=339 Score = 276 bits (707), Expect = 2e-72, Method: Compositional matrix adjust. Identities = 162/269 (61%), Positives = 189/269 (71%), Gaps = 2/269 (0%) Query 8 VMGVLNVTDDSFSDGGCYLDLDDAVKHGLAMAAAGAGIVDVGGESSRPGATRVDPAVETS 67 VMGVLNVT DSFSDGG Y DLD AV HG+ + GA ++DVGGES+RPGA RVD ET+ Sbjct 38 VMGVLNVTPDSFSDGGRYADLDAAVAHGVRLRGEGADLIDVGGESTRPGAERVDAETETA 97 Query 68 RVIPVVKELAAQGITVSIDTMRADVARAALQNGAQMVNDVSGGRADPAMGPLLAEADVPW 127 RV+PVV+EL+A GI VSIDT RA VA A L GA +VNDVSGG ADP M ++ +A PW Sbjct 98 RVLPVVRELSAAGILVSIDTSRARVAEAVLAAGAYVVNDVSGGLADPDMARVVRDAGCPW 157 Query 128 VLMHWRAVSADTPHVPVRYGNVVAEVRADLLASVADAVAAGVDPARLVLDPGLGFAKTAQ 187 VLMHWR S + Y +VVAEVR +L V A+AAGV R+++DPGLGFAKTA Sbjct 158 VLMHWRGHSRGMRELAT-YTDVVAEVRDELSRRVDAALAAGVAADRIIVDPGLGFAKTAA 216 Query 188 HNWAILHALPELVATGIPVLVGASRKRFLGALLAGPDGVMRPTDGRDTATAVISALAALH 247 HNWA+ LPELV G PVL GASRK +LG LLA P G RPT GR+ AT S LA Sbjct 217 HNWALSARLPELVDLGFPVLFGASRKSYLGRLLADPAGEPRPTAGREAATVATSVLAVAA 276 Query 248 GAWGVRVHDVRASVDAIKVVEAWMGAERI 276 GAWGVRVHDVRA+ DA+ V A G+ R+ Sbjct 277 GAWGVRVHDVRATADALAVWRA-TGSPRL 304 >gi|291006243|ref|ZP_06564216.1| 7,8-dihydropteroate synthase (partial match) [Saccharopolyspora erythraea NRRL 2338] Length=283 Score = 275 bits (703), Expect = 5e-72, Method: Compositional matrix adjust. Identities = 164/269 (61%), Positives = 188/269 (70%), Gaps = 1/269 (0%) Query 2 SPAPVQVMGVLNVTDDSFSDGGCYLDLDDAVKHGLAMAAAGAGIVDVGGESSRPGATRVD 61 +P VMGVLNVT DSFSDGG YLD AV HG+ M AGA IVDVGGES+RPG+ RVD Sbjct 8 NPRRCAVMGVLNVTPDSFSDGGRYLDRAAAVAHGVEMHRAGADIVDVGGESTRPGSERVD 67 Query 62 PAVETSRVIPVVKELAAQGITVSIDTMRADVARAALQNGAQMVNDVSGGRADPAMGPLLA 121 E RV+PVV EL AQG+ VS+DT RA VA A ++ GA ++NDVSGG ADP M + A Sbjct 68 AETEIDRVLPVVTELVAQGVPVSVDTTRARVAAATVRAGATVINDVSGGLADPDMAKVAA 127 Query 122 EADVPWVLMHWRAVSADTPHVPVRYGNVVAEVRADLLASVADAVAAGVDPARLVLDPGLG 181 E VPWVLMHWR S + + V Y +VV EVR +L V A+ AGV +VLDPGLG Sbjct 128 ETGVPWVLMHWRGHSKNMNSLAV-YTDVVTEVRDELRRQVDVALEAGVSEDAIVLDPGLG 186 Query 182 FAKTAQHNWAILHALPELVATGIPVLVGASRKRFLGALLAGPDGVMRPTDGRDTATAVIS 241 FAKT +W +L L LV G PVLVGASRKRFLG LLA DG RP GR+TATAV+S Sbjct 187 FAKTGADDWLLLQRLEVLVDLGFPVLVGASRKRFLGRLLADADGNPRPPAGRETATAVVS 246 Query 242 ALAALHGAWGVRVHDVRASVDAIKVVEAW 270 ALAA GAWGVRVHDV AS+DA+ V AW Sbjct 247 ALAADRGAWGVRVHDVVASLDAVAVTAAW 275 >gi|315503407|ref|YP_004082294.1| dihydropteroate synthase [Micromonospora sp. L5] gi|315410026|gb|ADU08143.1| dihydropteroate synthase [Micromonospora sp. L5] Length=339 Score = 275 bits (703), Expect = 6e-72, Method: Compositional matrix adjust. Identities = 161/269 (60%), Positives = 188/269 (70%), Gaps = 2/269 (0%) Query 8 VMGVLNVTDDSFSDGGCYLDLDDAVKHGLAMAAAGAGIVDVGGESSRPGATRVDPAVETS 67 VMGVLNVT DSFSDGG Y DLD AV HG+ + GA ++DVGGES+RPGA RVD ET+ Sbjct 38 VMGVLNVTPDSFSDGGRYADLDAAVAHGVRLRGEGADLIDVGGESTRPGAERVDAETETA 97 Query 68 RVIPVVKELAAQGITVSIDTMRADVARAALQNGAQMVNDVSGGRADPAMGPLLAEADVPW 127 RV+PVV+EL+A GI VSIDT RA VA A L GA +VNDVSGG ADP M ++ +A PW Sbjct 98 RVLPVVRELSAAGILVSIDTSRARVAEAVLAAGAYVVNDVSGGLADPDMARVVRDAGCPW 157 Query 128 VLMHWRAVSADTPHVPVRYGNVVAEVRADLLASVADAVAAGVDPARLVLDPGLGFAKTAQ 187 VLMHWR S + Y +VVAEVR +L V A+AAGV R+++DPGLGFAKTA Sbjct 158 VLMHWRGHSRGMRELAT-YTDVVAEVRDELSRRVDAALAAGVAADRIIVDPGLGFAKTAA 216 Query 188 HNWAILHALPELVATGIPVLVGASRKRFLGALLAGPDGVMRPTDGRDTATAVISALAALH 247 HNWA+ LPELV G PVL GASRK +LG LLA P G RPT GR+ AT S LA Sbjct 217 HNWALSARLPELVDLGFPVLFGASRKSYLGRLLADPAGEPRPTAGREAATVATSVLAVAA 276 Query 248 GAWGVRVHDVRASVDAIKVVEAWMGAERI 276 GAWGVRVHDVR + DA+ V A G+ R+ Sbjct 277 GAWGVRVHDVRGTADALAVWRA-TGSPRL 304 >gi|134097011|ref|YP_001102672.1| 7,8-dihydropteroate synthase (partial match) [Saccharopolyspora erythraea NRRL 2338] gi|133909634|emb|CAL99746.1| 7,8-dihydropteroate synthase (partial match) [Saccharopolyspora erythraea NRRL 2338] Length=269 Score = 273 bits (698), Expect = 2e-71, Method: Compositional matrix adjust. Identities = 162/262 (62%), Positives = 185/262 (71%), Gaps = 1/262 (0%) Query 9 MGVLNVTDDSFSDGGCYLDLDDAVKHGLAMAAAGAGIVDVGGESSRPGATRVDPAVETSR 68 MGVLNVT DSFSDGG YLD AV HG+ M AGA IVDVGGES+RPG+ RVD E R Sbjct 1 MGVLNVTPDSFSDGGRYLDRAAAVAHGVEMHRAGADIVDVGGESTRPGSERVDAETEIDR 60 Query 69 VIPVVKELAAQGITVSIDTMRADVARAALQNGAQMVNDVSGGRADPAMGPLLAEADVPWV 128 V+PVV EL AQG+ VS+DT RA VA A ++ GA ++NDVSGG ADP M + AE VPWV Sbjct 61 VLPVVTELVAQGVPVSVDTTRARVAAATVRAGATVINDVSGGLADPDMAKVAAETGVPWV 120 Query 129 LMHWRAVSADTPHVPVRYGNVVAEVRADLLASVADAVAAGVDPARLVLDPGLGFAKTAQH 188 LMHWR S + + V Y +VV EVR +L V A+ AGV +VLDPGLGFAKT Sbjct 121 LMHWRGHSKNMNSLAV-YTDVVTEVRDELRRQVDVALEAGVSEDAIVLDPGLGFAKTGAD 179 Query 189 NWAILHALPELVATGIPVLVGASRKRFLGALLAGPDGVMRPTDGRDTATAVISALAALHG 248 +W +L L LV G PVLVGASRKRFLG LLA DG RP GR+TATAV+SALAA G Sbjct 180 DWLLLQRLEVLVDLGFPVLVGASRKRFLGRLLADADGNPRPPAGRETATAVVSALAADRG 239 Query 249 AWGVRVHDVRASVDAIKVVEAW 270 AWGVRVHDV AS+DA+ V AW Sbjct 240 AWGVRVHDVVASLDAVAVTAAW 261 >gi|330470501|ref|YP_004408244.1| dihydropteroate synthase [Verrucosispora maris AB-18-032] gi|328813472|gb|AEB47644.1| dihydropteroate synthase [Verrucosispora maris AB-18-032] Length=300 Score = 271 bits (694), Expect = 6e-71, Method: Compositional matrix adjust. Identities = 166/268 (62%), Positives = 196/268 (74%), Gaps = 2/268 (0%) Query 2 SPAPVQVMGVLNVTDDSFSDGGCYLDLDDAVKHGLAMAAAGAGIVDVGGESSRPGATRVD 61 +PAPV VMGVLNVT DSFSDGG Y D+ AV HG+ + GAG+VDVGGES+RPGA RVD Sbjct 7 APAPV-VMGVLNVTPDSFSDGGRYADVGAAVAHGVRLRDEGAGLVDVGGESTRPGAERVD 65 Query 62 PAVETSRVIPVVKELAAQGITVSIDTMRADVARAALQNGAQMVNDVSGGRADPAMGPLLA 121 P E +RV+PV++ELA G+ VSIDT RA VA AAL GA +VNDVSGG ADP M ++A Sbjct 66 PETEVARVVPVIRELAGAGVPVSIDTTRARVAAAALAAGAVVVNDVSGGLADPDMARVVA 125 Query 122 EADVPWVLMHWRAVSADTPHVPVRYGNVVAEVRADLLASVADAVAAGVDPARLVLDPGLG 181 +A PWVLMHWR S + Y +VVA+VRA+L V A+AAGV R+V+DPGLG Sbjct 126 DAGCPWVLMHWRGHSRRMTELAA-YDDVVADVRAELGQRVEAALAAGVAADRIVIDPGLG 184 Query 182 FAKTAQHNWAILHALPELVATGIPVLVGASRKRFLGALLAGPDGVMRPTDGRDTATAVIS 241 FAKTA HNW + LPEL+ G P+L GASRK +LG LLAGPDGV RPT GR +AT S Sbjct 185 FAKTAAHNWQLSARLPELLELGYPLLFGASRKSYLGLLLAGPDGVPRPTGGRGSATVATS 244 Query 242 ALAALHGAWGVRVHDVRASVDAIKVVEA 269 LA GAWGVRVHDVRA+VDA+ V +A Sbjct 245 LLAVAAGAWGVRVHDVRATVDALAVWQA 272 >gi|333025307|ref|ZP_08453371.1| putative dihydropteroate synthase [Streptomyces sp. Tu6071] gi|332745159|gb|EGJ75600.1| putative dihydropteroate synthase [Streptomyces sp. Tu6071] Length=284 Score = 271 bits (693), Expect = 9e-71, Method: Compositional matrix adjust. Identities = 153/263 (59%), Positives = 187/263 (72%), Gaps = 2/263 (0%) Query 8 VMGVLNVTDDSFSDGGCYLDLDDAVKHGLAMAAAGAGIVDVGGESSRPGATRVDPAVETS 67 VMGV+NVT DSFSDGG + D + AVKHGL + A GA +VDVGGES+RPGA+RVD A E Sbjct 18 VMGVVNVTPDSFSDGGRWFDTEAAVKHGLELVAQGADLVDVGGESTRPGASRVDEAEELR 77 Query 68 RVIPVVKELAAQGITVSIDTMRADVARAALQNGAQMVNDVSGGRADPAMGPLLAEADVPW 127 RV+PVV+ LAA+G+T+S+DTMRA VA AAL GA +VNDVSGG AD AM P++A P+ Sbjct 78 RVVPVVRALAAEGVTLSVDTMRARVAEAALDAGAHLVNDVSGGLADAAMVPMVAATGAPF 137 Query 128 VLMHWRAVSADTPHVPVRYGNVVAEVRADLLASVADAVAAGVDPARLVLDPGLGFAKTAQ 187 V+MHWR S D V Y +VV EV ++L +A V AGV P R++LDPGLGFAK + Sbjct 138 VVMHWRGFSEDMNARAV-YADVVGEVVSELEQRMAAVVGAGVAPERVLLDPGLGFAKATE 196 Query 188 HNWAILHALPELVATGIPVLVGASRKRFLGALLAGPDGVM-RPTDGRDTATAVISALAAL 246 H+ +L L L A G P+LV ASRKRFLG +LAG P RD ATA +SAL+A Sbjct 197 HDLVLLAHLDRLRALGRPLLVAASRKRFLGRVLAGDTSAAPPPARERDAATAAVSALSAA 256 Query 247 HGAWGVRVHDVRASVDAIKVVEA 269 GAWGVRVH+VRAS DA++V A Sbjct 257 GGAWGVRVHEVRASADAVRVARA 279 >gi|145596806|ref|YP_001161103.1| dihydropteroate synthase [Salinispora tropica CNB-440] gi|145306143|gb|ABP56725.1| dihydropteroate synthase [Salinispora tropica CNB-440] Length=486 Score = 271 bits (692), Expect = 1e-70, Method: Compositional matrix adjust. Identities = 155/262 (60%), Positives = 188/262 (72%), Gaps = 2/262 (0%) Query 8 VMGVLNVTDDSFSDGGCYLDLDDAVKHGLAMAAAGAGIVDVGGESSRPGATRVDPAVETS 67 VMG+LNVT DSFSDGG Y DLD A+ HG+ + GA +VDVGGES+RPGA RV E + Sbjct 208 VMGILNVTPDSFSDGGRYADLDAAIAHGVRLRGDGAHLVDVGGESTRPGADRVAAETEAA 267 Query 68 RVIPVVKELAAQGITVSIDTMRADVARAALQNGAQMVNDVSGGRADPAMGPLLAEADVPW 127 RV PV++ELAA G+ VSIDT RA VA AL GA++VNDVSGG ADP M ++ +A PW Sbjct 268 RVRPVIRELAAAGVPVSIDTTRARVAELALAAGARVVNDVSGGLADPDMARVVRDAGCPW 327 Query 128 VLMHWRAVSADTPHVPVRYGNVVAEVRADLLASVADAVAAGVDPARLVLDPGLGFAKTAQ 187 VLMHWR S + + RYG+VVA+V+A+L V A+AAGV R+V+DPGLGFAKTA Sbjct 328 VLMHWRGHSREMREL-ARYGDVVADVKAELAQRVEAALAAGVAADRIVIDPGLGFAKTAA 386 Query 188 HNWAILHALPELVATGIPVLVGASRKRFLGALLAGPDGVMRPTDGRDTATAVISALAALH 247 HNW + LPEL+A G P+L ASRK LGALLA DG RPT+GR+ AT S LA Sbjct 387 HNWELSARLPELLALGYPLLFAASRKSHLGALLAA-DGAPRPTEGREVATVATSVLAVAA 445 Query 248 GAWGVRVHDVRASVDAIKVVEA 269 GAWGVRVHDV+A+ DA+ V +A Sbjct 446 GAWGVRVHDVQATADALAVWQA 467 >gi|318061590|ref|ZP_07980311.1| dihydropteroate synthase [Streptomyces sp. SA3_actG] gi|318077174|ref|ZP_07984506.1| dihydropteroate synthase [Streptomyces sp. SA3_actF] Length=266 Score = 270 bits (691), Expect = 1e-70, Method: Compositional matrix adjust. Identities = 152/262 (59%), Positives = 186/262 (71%), Gaps = 2/262 (0%) Query 9 MGVLNVTDDSFSDGGCYLDLDDAVKHGLAMAAAGAGIVDVGGESSRPGATRVDPAVETSR 68 MGV+NVT DSFSDGG + D + AVKHGL + A GA +VDVGGES+RPGA+RVD A E R Sbjct 1 MGVVNVTPDSFSDGGRWFDTEAAVKHGLELVAQGADLVDVGGESTRPGASRVDEAEELRR 60 Query 69 VIPVVKELAAQGITVSIDTMRADVARAALQNGAQMVNDVSGGRADPAMGPLLAEADVPWV 128 V+PVV+ LAA+G+T+S+DTMRA VA AAL GA +VNDVSGG AD AM P++A P+V Sbjct 61 VVPVVRALAAEGVTLSVDTMRARVAEAALDAGAHLVNDVSGGLADAAMVPMVAATGAPFV 120 Query 129 LMHWRAVSADTPHVPVRYGNVVAEVRADLLASVADAVAAGVDPARLVLDPGLGFAKTAQH 188 +MHWR S D V Y +VV EV ++L +A V AGV P R++LDPGLGFAK +H Sbjct 121 VMHWRGFSEDMNARAV-YADVVGEVVSELEQRMAAVVGAGVAPERVLLDPGLGFAKATEH 179 Query 189 NWAILHALPELVATGIPVLVGASRKRFLGALLAGPDGVM-RPTDGRDTATAVISALAALH 247 + +L L L A G P+LV ASRKRFLG +LAG P RD ATA +SAL+A Sbjct 180 DLVLLAHLDRLRALGRPLLVAASRKRFLGRVLAGDTSAAPPPARERDAATAAVSALSAAG 239 Query 248 GAWGVRVHDVRASVDAIKVVEA 269 GAWGVRVH+VRAS DA++V A Sbjct 240 GAWGVRVHEVRASADAVRVARA 261 >gi|170780557|ref|YP_001708889.1| putative dihydropteroate synthase [Clavibacter michiganensis subsp. sepedonicus] gi|169155125|emb|CAQ00225.1| putative dihydropteroate synthase [Clavibacter michiganensis subsp. sepedonicus] Length=291 Score = 268 bits (685), Expect = 7e-70, Method: Compositional matrix adjust. Identities = 155/263 (59%), Positives = 186/263 (71%), Gaps = 5/263 (1%) Query 8 VMGVLNVTDDSFSDGGCYLDLDDAVKHGLAMAAAGAGIVDVGGESSRPGATRVDPAVETS 67 VMG+LN T DSFSDGG +L LDDA+ H M AAGA +VDVGGES+RPGA RVD A E + Sbjct 12 VMGILNATPDSFSDGGRHLALDDALAHARRMVAAGADLVDVGGESTRPGAARVDAAEERA 71 Query 68 RVIPVVKELAAQGITVSIDTMRADVARAALQNGAQMVNDVSGGRADPAMGPLLAEADVPW 127 RV+PVV+ELAA+GI VS+DTMRA A A + GA++VNDVSGG ADP M ++A ADV + Sbjct 72 RVVPVVRELAAEGIAVSVDTMRAATAEACVAVGARIVNDVSGGLADPGMAAVVAGADVDY 131 Query 128 VLMHWRAVSADTPHVPVRYGNVVAEVRADLLASVADAVAAGVDPARLVLDPGLGFAKTAQ 187 V MHWR S D Y + V EVR +LLA + VAAG+DPAR++LDPGLGFAK A Sbjct 132 VAMHWRGHS-DMMAARATYADTVGEVRDELLARIDALVAAGLDPARVILDPGLGFAKDAA 190 Query 188 HNWAILHALPELVATGIPVLVGASRKRFLGALLAGPDGVMRPTDGRDTATAVISALAALH 247 H+W +L +L L G VLVGASRKRFLG LL P+G + RD TAV+SAL+A Sbjct 191 HDWQLLGSLDALTGLGHRVLVGASRKRFLGRLL--PEGA--GVEDRDVPTAVVSALSARA 246 Query 248 GAWGVRVHDVRASVDAIKVVEAW 270 GAW VRVHDV ++ AI V AW Sbjct 247 GAWAVRVHDVASTRAAIGVEAAW 269 >gi|297563887|ref|YP_003682860.1| dihydropteroate synthase [Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111] gi|296848336|gb|ADH70354.1| dihydropteroate synthase [Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111] Length=300 Score = 268 bits (684), Expect = 9e-70, Method: Compositional matrix adjust. Identities = 146/265 (56%), Positives = 182/265 (69%), Gaps = 3/265 (1%) Query 8 VMGVLNVTDDSFSDGGCYLDLDDAVKHGLAMAAAGAGIVDVGGESSRPGATRVDPAVETS 67 VMGV+NVT DSFSDGG + D D A++HG+ +A GA +VDVGGES+RPGA RV A E Sbjct 18 VMGVVNVTPDSFSDGGAWFDPDRAIEHGMRLAEEGADLVDVGGESTRPGAQRVSAAEELR 77 Query 68 RVIPVVKELAAQGITVSIDTMRADVARAALQNGAQMVNDVSGGRADPAMGPLLAEADVPW 127 RV PVV+EL+A+G+ VS+DTMRA++A A++ GA +VNDVSGG ADPAM L+A + V + Sbjct 78 RVEPVVRELSARGVAVSVDTMRAEIAEKAVEAGAVLVNDVSGGLADPAMARLVASSGVAY 137 Query 128 VLMHWRAVSADTPHVPVRYGNVVAEVRADLLASVADAVAAGVDPARLVLDPGLGFAKTAQ 187 VLMHWR S D V Y +VV EV +L + ++AGVDP ++VLDPGLGF+K + Sbjct 138 VLMHWRGHSHDMQSRAV-YTDVVQEVLDELRDRMEAMISAGVDPGQIVLDPGLGFSKRPE 196 Query 188 --HNWAILHALPELVATGIPVLVGASRKRFLGALLAGPDGVMRPTDGRDTATAVISALAA 245 HNWA+LH L G PVLV SRKRFL LL G RP D ATA ++ L+A Sbjct 197 QAHNWALLHELERFHELGRPVLVAGSRKRFLSRLLGDAKGEDRPFTECDAATAAVTTLSA 256 Query 246 LHGAWGVRVHDVRASVDAIKVVEAW 270 GAW VRVHDVR S DA++V AW Sbjct 257 DRGAWAVRVHDVRPSADAVRVAAAW 281 Lambda K H 0.318 0.134 0.397 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 442782057568 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40