BLASTP 2.2.25+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.



Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
           15,229,318 sequences; 5,219,829,388 total letters



Query= Rv3609c

Length=202
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

gi|15610745|ref|NP_218126.1|  GTP cyclohydrolase I [Mycobacterium...   412    2e-113
gi|289748123|ref|ZP_06507501.1|  GTP cyclohydrolase I folE [Mycob...   411    3e-113
gi|342862040|ref|ZP_08718684.1|  GTP cyclohydrolase I [Mycobacter...   366    1e-99 
gi|336458519|gb|EGO37490.1|  GTP cyclohydrolase I [Mycobacterium ...   366    1e-99 
gi|41406547|ref|NP_959383.1|  GTP cyclohydrolase I [Mycobacterium...   366    1e-99 
gi|296166675|ref|ZP_06849100.1|  GTP cyclohydrolase I [Mycobacter...   365    2e-99 
gi|118464289|ref|YP_879823.1|  GTP cyclohydrolase I [Mycobacteriu...   365    2e-99 
gi|254773202|ref|ZP_05214718.1|  GTP cyclohydrolase I [Mycobacter...   365    3e-99 
gi|240172852|ref|ZP_04751511.1|  GTP cyclohydrolase I [Mycobacter...   363    1e-98 
gi|183985080|ref|YP_001853371.1|  GTP cyclohydrolase I FolE [Myco...   360    6e-98 
gi|254822682|ref|ZP_05227683.1|  GTP cyclohydrolase I [Mycobacter...   360    8e-98 
gi|118619365|ref|YP_907697.1|  GTP cyclohydrolase I [Mycobacteriu...   359    1e-97 
gi|15827020|ref|NP_301283.1|  GTP cyclohydrolase I [Mycobacterium...   351    4e-95 
gi|108801732|ref|YP_641929.1|  GTP cyclohydrolase I [Mycobacteriu...   345    3e-93 
gi|145222009|ref|YP_001132687.1|  GTP cyclohydrolase I [Mycobacte...   343    6e-93 
gi|126437719|ref|YP_001073410.1|  GTP cyclohydrolase I [Mycobacte...   343    9e-93 
gi|118473408|ref|YP_890325.1|  GTP cyclohydrolase I [Mycobacteriu...   342    1e-92 
gi|315446251|ref|YP_004079130.1|  GTP cyclohydrolase I [Mycobacte...   341    4e-92 
gi|120406319|ref|YP_956148.1|  GTP cyclohydrolase I [Mycobacteriu...   339    2e-91 
gi|333992538|ref|YP_004525152.1|  GTP cyclohydrolase I FolE [Myco...   338    2e-91 
gi|343924377|ref|ZP_08763927.1|  GTP cyclohydrolase I [Gordonia a...   337    7e-91 
gi|325675046|ref|ZP_08154733.1|  GTP cyclohydrolase I [Rhodococcu...   336    1e-90 
gi|312138053|ref|YP_004005389.1|  gtp cyclohydrolase i [Rhodococc...   335    2e-90 
gi|169627638|ref|YP_001701287.1|  GTP cyclohydrolase I [Mycobacte...   335    3e-90 
gi|111021380|ref|YP_704352.1|  GTP cyclohydrolase I [Rhodococcus ...   333    1e-89 
gi|326384086|ref|ZP_08205769.1|  GTP cyclohydrolase I [Gordonia n...   332    2e-89 
gi|226363734|ref|YP_002781516.1|  GTP cyclohydrolase I [Rhodococc...   331    4e-89 
gi|111026413|ref|YP_708696.1|  GTP cyclohydrolase I [Rhodococcus ...   330    6e-89 
gi|54022363|ref|YP_116605.1|  GTP cyclohydrolase I [Nocardia farc...   329    1e-88 
gi|262203871|ref|YP_003275079.1|  GTP cyclohydrolase I [Gordonia ...   328    2e-88 
gi|333917990|ref|YP_004491571.1|  GTP cyclohydrolase 1 [Amycolici...   328    3e-88 
gi|226304115|ref|YP_002764073.1|  GTP cyclohydrolase I [Rhodococc...   325    2e-87 
gi|229494246|ref|ZP_04388009.1|  GTP cyclohydrolase I [Rhodococcu...   325    3e-87 
gi|23429479|gb|AAM97307.1|  GTP cyclohydrolase I [Nocardia iowensis]   324    6e-87 
gi|226364783|ref|YP_002782565.1|  GTP cyclohydrolase I [Rhodococc...   317    7e-85 
gi|296138296|ref|YP_003645539.1|  GTP cyclohydrolase I [Tsukamure...   315    2e-84 
gi|256374469|ref|YP_003098129.1|  GTP cyclohydrolase I [Actinosyn...   309    2e-82 
gi|302530788|ref|ZP_07283130.1|  GTP cyclohydrolase I [Streptomyc...   306    1e-81 
gi|300790551|ref|YP_003770842.1|  GTP cyclohydrolase I [Amycolato...   304    5e-81 
gi|340532238|gb|AEK47443.1|  GTP cyclohydrolase I [Amycolatopsis ...   302    2e-80 
gi|257057515|ref|YP_003135347.1|  GTP cyclohydrolase I [Saccharom...   301    4e-80 
gi|38234565|ref|NP_940332.1|  GTP cyclohydrolase I [Corynebacteri...   298    2e-79 
gi|325000126|ref|ZP_08121238.1|  GTP cyclohydrolase I [Pseudonoca...   298    3e-79 
gi|25029097|ref|NP_739151.1|  GTP cyclohydrolase I [Corynebacteri...   297    6e-79 
gi|331699842|ref|YP_004336081.1|  GTP cyclohydrolase 1 [Pseudonoc...   296    9e-79 
gi|213965109|ref|ZP_03393307.1|  GTP cyclohydrolase I [Corynebact...   296    9e-79 
gi|134097010|ref|YP_001102671.1|  GTP cyclohydrolase I [Saccharop...   296    1e-78 
gi|300859208|ref|YP_003784191.1|  GTP cyclohydrolase I [Corynebac...   295    2e-78 
gi|258651093|ref|YP_003200249.1|  GTP cyclohydrolase I [Nakamurel...   295    3e-78 
gi|337291625|ref|YP_004630646.1|  GTP cyclohydrolase I [Corynebac...   295    3e-78 


>gi|15610745|ref|NP_218126.1| GTP cyclohydrolase I [Mycobacterium tuberculosis H37Rv]
 gi|15843221|ref|NP_338258.1| GTP cyclohydrolase I [Mycobacterium tuberculosis CDC1551]
 gi|31794785|ref|NP_857278.1| GTP cyclohydrolase I [Mycobacterium bovis AF2122/97]
 83 more sequence titles
 Length=202

 Score =  412 bits (1058),  Expect = 2e-113, Method: Compositional matrix adjust.
 Identities = 202/202 (100%), Positives = 202/202 (100%), Gaps = 0/202 (0%)

Query  1    MSQLDSRSASARIRVFDQQRAEAAVRELLYAIGEDPDRDGLVATPSRVARSYREMFAGLY  60
            MSQLDSRSASARIRVFDQQRAEAAVRELLYAIGEDPDRDGLVATPSRVARSYREMFAGLY
Sbjct  1    MSQLDSRSASARIRVFDQQRAEAAVRELLYAIGEDPDRDGLVATPSRVARSYREMFAGLY  60

Query  61   TDPDSVLNTMFDEDHDELVLVKEIPMYSTCEHHLVAFHGVAHVGYIPGDDGRVTGLSKIA  120
            TDPDSVLNTMFDEDHDELVLVKEIPMYSTCEHHLVAFHGVAHVGYIPGDDGRVTGLSKIA
Sbjct  61   TDPDSVLNTMFDEDHDELVLVKEIPMYSTCEHHLVAFHGVAHVGYIPGDDGRVTGLSKIA  120

Query  121  RLVDLYAKRPQVQERLTSQIADALMKKLDPRGVIVVIEAEHLCMAMRGVRKPGSVTTTSA  180
            RLVDLYAKRPQVQERLTSQIADALMKKLDPRGVIVVIEAEHLCMAMRGVRKPGSVTTTSA
Sbjct  121  RLVDLYAKRPQVQERLTSQIADALMKKLDPRGVIVVIEAEHLCMAMRGVRKPGSVTTTSA  180

Query  181  VRGLFKTNAASRAEALDLILRK  202
            VRGLFKTNAASRAEALDLILRK
Sbjct  181  VRGLFKTNAASRAEALDLILRK  202


>gi|289748123|ref|ZP_06507501.1| GTP cyclohydrolase I folE [Mycobacterium tuberculosis T92]
 gi|289688710|gb|EFD56139.1| GTP cyclohydrolase I folE [Mycobacterium tuberculosis T92]
Length=202

 Score =  411 bits (1056),  Expect = 3e-113, Method: Compositional matrix adjust.
 Identities = 201/202 (99%), Positives = 202/202 (100%), Gaps = 0/202 (0%)

Query  1    MSQLDSRSASARIRVFDQQRAEAAVRELLYAIGEDPDRDGLVATPSRVARSYREMFAGLY  60
            MSQLDSRSASARIRVFDQQRAEAAVRELLYAIGEDPDRDGLVATPSRVARSYREMFAGLY
Sbjct  1    MSQLDSRSASARIRVFDQQRAEAAVRELLYAIGEDPDRDGLVATPSRVARSYREMFAGLY  60

Query  61   TDPDSVLNTMFDEDHDELVLVKEIPMYSTCEHHLVAFHGVAHVGYIPGDDGRVTGLSKIA  120
            TDPDSVLNTMFDEDHDELVLVKEIPMYSTCEHHLVAFHGVAHVGY+PGDDGRVTGLSKIA
Sbjct  61   TDPDSVLNTMFDEDHDELVLVKEIPMYSTCEHHLVAFHGVAHVGYVPGDDGRVTGLSKIA  120

Query  121  RLVDLYAKRPQVQERLTSQIADALMKKLDPRGVIVVIEAEHLCMAMRGVRKPGSVTTTSA  180
            RLVDLYAKRPQVQERLTSQIADALMKKLDPRGVIVVIEAEHLCMAMRGVRKPGSVTTTSA
Sbjct  121  RLVDLYAKRPQVQERLTSQIADALMKKLDPRGVIVVIEAEHLCMAMRGVRKPGSVTTTSA  180

Query  181  VRGLFKTNAASRAEALDLILRK  202
            VRGLFKTNAASRAEALDLILRK
Sbjct  181  VRGLFKTNAASRAEALDLILRK  202


>gi|342862040|ref|ZP_08718684.1| GTP cyclohydrolase I [Mycobacterium colombiense CECT 3035]
 gi|342130580|gb|EGT83889.1| GTP cyclohydrolase I [Mycobacterium colombiense CECT 3035]
Length=193

 Score =  366 bits (940),  Expect = 1e-99, Method: Compositional matrix adjust.
 Identities = 175/189 (93%), Positives = 186/189 (99%), Gaps = 0/189 (0%)

Query  14   RVFDQQRAEAAVRELLYAIGEDPDRDGLVATPSRVARSYREMFAGLYTDPDSVLNTMFDE  73
            R FDQ+RAEAAVRELL+AIGEDPDRDGL  TP+RVAR+YREMFAGLYTDPDSVLNTMFDE
Sbjct  5    RAFDQERAEAAVRELLHAIGEDPDRDGLRETPARVARAYREMFAGLYTDPDSVLNTMFDE  64

Query  74   DHDELVLVKEIPMYSTCEHHLVAFHGVAHVGYIPGDDGRVTGLSKIARLVDLYAKRPQVQ  133
            DHDELVLVKEIP+YSTCEHHLVAFHGVAHVGYIPG+DGRVTGLSKIARLVDLY+KRPQVQ
Sbjct  65   DHDELVLVKEIPLYSTCEHHLVAFHGVAHVGYIPGNDGRVTGLSKIARLVDLYSKRPQVQ  124

Query  134  ERLTSQIADALMKKLDPRGVIVVIEAEHLCMAMRGVRKPGSVTTTSAVRGLFKTNAASRA  193
            ERLTSQIADAL+KKL+PRGVIVV+EAEHLCMAMRGVRKPG+VTTTSAVRGLFKTNAASRA
Sbjct  125  ERLTSQIADALVKKLNPRGVIVVVEAEHLCMAMRGVRKPGAVTTTSAVRGLFKTNAASRA  184

Query  194  EALDLILRK  202
            EALDLILRK
Sbjct  185  EALDLILRK  193


>gi|336458519|gb|EGO37490.1| GTP cyclohydrolase I [Mycobacterium avium subsp. paratuberculosis 
S397]
Length=204

 Score =  366 bits (939),  Expect = 1e-99, Method: Compositional matrix adjust.
 Identities = 174/195 (90%), Positives = 189/195 (97%), Gaps = 0/195 (0%)

Query  8    SASARIRVFDQQRAEAAVRELLYAIGEDPDRDGLVATPSRVARSYREMFAGLYTDPDSVL  67
            +A+ ++R FDQ RAEAAVRELL+AIGEDPDR GL  TP+RVAR+YREMFAGLYTDPDSVL
Sbjct  10   TATHQVRQFDQARAEAAVRELLFAIGEDPDRHGLAETPARVARAYREMFAGLYTDPDSVL  69

Query  68   NTMFDEDHDELVLVKEIPMYSTCEHHLVAFHGVAHVGYIPGDDGRVTGLSKIARLVDLYA  127
            NTMFDE+HDELVLVKEIP+YSTCEHHLV+FHGVAHVGYIPG+DGRVTGLSKIARLVDLYA
Sbjct  70   NTMFDEEHDELVLVKEIPLYSTCEHHLVSFHGVAHVGYIPGNDGRVTGLSKIARLVDLYA  129

Query  128  KRPQVQERLTSQIADALMKKLDPRGVIVVIEAEHLCMAMRGVRKPGSVTTTSAVRGLFKT  187
            KRPQVQERLTSQIADAL+KKL+PRGVIVV+EAEHLCMAMRGVRKPG+VTTTSAVRGLFKT
Sbjct  130  KRPQVQERLTSQIADALVKKLNPRGVIVVVEAEHLCMAMRGVRKPGAVTTTSAVRGLFKT  189

Query  188  NAASRAEALDLILRK  202
            NAASRAEALDLILRK
Sbjct  190  NAASRAEALDLILRK  204


>gi|41406547|ref|NP_959383.1| GTP cyclohydrolase I [Mycobacterium avium subsp. paratuberculosis 
K-10]
 gi|81571515|sp|Q743Z2.1|GCH1_MYCPA RecName: Full=GTP cyclohydrolase 1; AltName: Full=GTP cyclohydrolase 
I; Short=GTP-CH-I
 gi|41394896|gb|AAS02766.1| FolE [Mycobacterium avium subsp. paratuberculosis K-10]
Length=204

 Score =  366 bits (939),  Expect = 1e-99, Method: Compositional matrix adjust.
 Identities = 174/195 (90%), Positives = 189/195 (97%), Gaps = 0/195 (0%)

Query  8    SASARIRVFDQQRAEAAVRELLYAIGEDPDRDGLVATPSRVARSYREMFAGLYTDPDSVL  67
            +A+ ++R FDQ RAEAAVRELL+AIGEDPDR GL  TP+RVAR+YREMFAGLYTDPDSVL
Sbjct  10   TATHQVRQFDQARAEAAVRELLFAIGEDPDRHGLAETPARVARAYREMFAGLYTDPDSVL  69

Query  68   NTMFDEDHDELVLVKEIPMYSTCEHHLVAFHGVAHVGYIPGDDGRVTGLSKIARLVDLYA  127
            NTMFDE+HDELVLVKEIP+YSTCEHHLV+FHGVAHVGYIPG+DGRVTGLSKIARLVDLYA
Sbjct  70   NTMFDEEHDELVLVKEIPLYSTCEHHLVSFHGVAHVGYIPGNDGRVTGLSKIARLVDLYA  129

Query  128  KRPQVQERLTSQIADALMKKLDPRGVIVVIEAEHLCMAMRGVRKPGSVTTTSAVRGLFKT  187
            KRPQVQERLTSQIADAL+KKL+PRGVIVV+EAEHLCMAMRGVRKPG+VTTTSAVRGLFKT
Sbjct  130  KRPQVQERLTSQIADALVKKLNPRGVIVVVEAEHLCMAMRGVRKPGAVTTTSAVRGLFKT  189

Query  188  NAASRAEALDLILRK  202
            NAASRAEALDLILRK
Sbjct  190  NAASRAEALDLILRK  204


>gi|296166675|ref|ZP_06849100.1| GTP cyclohydrolase I [Mycobacterium parascrofulaceum ATCC BAA-614]
 gi|295897940|gb|EFG77521.1| GTP cyclohydrolase I [Mycobacterium parascrofulaceum ATCC BAA-614]
Length=204

 Score =  365 bits (938),  Expect = 2e-99, Method: Compositional matrix adjust.
 Identities = 177/202 (88%), Positives = 190/202 (95%), Gaps = 0/202 (0%)

Query  1    MSQLDSRSASARIRVFDQQRAEAAVRELLYAIGEDPDRDGLVATPSRVARSYREMFAGLY  60
            ++ L   +AS  +RVFDQ RAEAAVRELLYAIGEDPDR GL  TP+RVAR+Y+EMFAGLY
Sbjct  3    LTGLGPDTASPALRVFDQARAEAAVRELLYAIGEDPDRHGLRETPARVARAYQEMFAGLY  62

Query  61   TDPDSVLNTMFDEDHDELVLVKEIPMYSTCEHHLVAFHGVAHVGYIPGDDGRVTGLSKIA  120
            TDPDSVLNTMFDE+HDELVLVKEIP+YSTCEHHLV+FHGVAHVGYIPG DGRVTGLSKIA
Sbjct  63   TDPDSVLNTMFDEEHDELVLVKEIPLYSTCEHHLVSFHGVAHVGYIPGADGRVTGLSKIA  122

Query  121  RLVDLYAKRPQVQERLTSQIADALMKKLDPRGVIVVIEAEHLCMAMRGVRKPGSVTTTSA  180
            RLVDLYAKRPQVQERLTSQIADALM KL+PRGVIVVIEAEHLCMAMRGVRKPG+VTTTSA
Sbjct  123  RLVDLYAKRPQVQERLTSQIADALMNKLNPRGVIVVIEAEHLCMAMRGVRKPGAVTTTSA  182

Query  181  VRGLFKTNAASRAEALDLILRK  202
            VRGLFKTNAASR+EALDLILRK
Sbjct  183  VRGLFKTNAASRSEALDLILRK  204


>gi|118464289|ref|YP_879823.1| GTP cyclohydrolase I [Mycobacterium avium 104]
 gi|226709644|sp|A0QA85.1|GCH1_MYCA1 RecName: Full=GTP cyclohydrolase 1; AltName: Full=GTP cyclohydrolase 
I; Short=GTP-CH-I
 gi|118165576|gb|ABK66473.1| GTP cyclohydrolase I [Mycobacterium avium 104]
Length=204

 Score =  365 bits (936),  Expect = 2e-99, Method: Compositional matrix adjust.
 Identities = 173/195 (89%), Positives = 189/195 (97%), Gaps = 0/195 (0%)

Query  8    SASARIRVFDQQRAEAAVRELLYAIGEDPDRDGLVATPSRVARSYREMFAGLYTDPDSVL  67
            +A+ ++R FDQ RAEAAVRELL+AIGE+PDR GL  TP+RVAR+YREMFAGLYTDPDSVL
Sbjct  10   TATHQVRQFDQARAEAAVRELLFAIGENPDRHGLAETPARVARAYREMFAGLYTDPDSVL  69

Query  68   NTMFDEDHDELVLVKEIPMYSTCEHHLVAFHGVAHVGYIPGDDGRVTGLSKIARLVDLYA  127
            NTMFDE+HDELVLVKEIP+YSTCEHHLV+FHGVAHVGYIPG+DGRVTGLSKIARLVDLYA
Sbjct  70   NTMFDEEHDELVLVKEIPLYSTCEHHLVSFHGVAHVGYIPGNDGRVTGLSKIARLVDLYA  129

Query  128  KRPQVQERLTSQIADALMKKLDPRGVIVVIEAEHLCMAMRGVRKPGSVTTTSAVRGLFKT  187
            KRPQVQERLTSQIADAL+KKL+PRGVIVV+EAEHLCMAMRGVRKPG+VTTTSAVRGLFKT
Sbjct  130  KRPQVQERLTSQIADALVKKLNPRGVIVVVEAEHLCMAMRGVRKPGAVTTTSAVRGLFKT  189

Query  188  NAASRAEALDLILRK  202
            NAASRAEALDLILRK
Sbjct  190  NAASRAEALDLILRK  204


>gi|254773202|ref|ZP_05214718.1| GTP cyclohydrolase I [Mycobacterium avium subsp. avium ATCC 25291]
Length=205

 Score =  365 bits (936),  Expect = 3e-99, Method: Compositional matrix adjust.
 Identities = 173/195 (89%), Positives = 189/195 (97%), Gaps = 0/195 (0%)

Query  8    SASARIRVFDQQRAEAAVRELLYAIGEDPDRDGLVATPSRVARSYREMFAGLYTDPDSVL  67
            +A+ ++R FDQ RAEAAVRELL+AIGE+PDR GL  TP+RVAR+YREMFAGLYTDPDSVL
Sbjct  11   TATHQVRQFDQARAEAAVRELLFAIGENPDRHGLAETPARVARAYREMFAGLYTDPDSVL  70

Query  68   NTMFDEDHDELVLVKEIPMYSTCEHHLVAFHGVAHVGYIPGDDGRVTGLSKIARLVDLYA  127
            NTMFDE+HDELVLVKEIP+YSTCEHHLV+FHGVAHVGYIPG+DGRVTGLSKIARLVDLYA
Sbjct  71   NTMFDEEHDELVLVKEIPLYSTCEHHLVSFHGVAHVGYIPGNDGRVTGLSKIARLVDLYA  130

Query  128  KRPQVQERLTSQIADALMKKLDPRGVIVVIEAEHLCMAMRGVRKPGSVTTTSAVRGLFKT  187
            KRPQVQERLTSQIADAL+KKL+PRGVIVV+EAEHLCMAMRGVRKPG+VTTTSAVRGLFKT
Sbjct  131  KRPQVQERLTSQIADALVKKLNPRGVIVVVEAEHLCMAMRGVRKPGAVTTTSAVRGLFKT  190

Query  188  NAASRAEALDLILRK  202
            NAASRAEALDLILRK
Sbjct  191  NAASRAEALDLILRK  205


>gi|240172852|ref|ZP_04751511.1| GTP cyclohydrolase I [Mycobacterium kansasii ATCC 12478]
Length=202

 Score =  363 bits (931),  Expect = 1e-98, Method: Compositional matrix adjust.
 Identities = 175/202 (87%), Positives = 190/202 (95%), Gaps = 0/202 (0%)

Query  1    MSQLDSRSASARIRVFDQQRAEAAVRELLYAIGEDPDRDGLVATPSRVARSYREMFAGLY  60
            M+QLDSR  S+  R FDQ RAEAAVRELL AIGEDPDR GL  TP+RVAR+Y+E+FAGLY
Sbjct  1    MTQLDSRPTSSLPRAFDQPRAEAAVRELLCAIGEDPDRGGLRDTPARVARAYKEIFAGLY  60

Query  61   TDPDSVLNTMFDEDHDELVLVKEIPMYSTCEHHLVAFHGVAHVGYIPGDDGRVTGLSKIA  120
            TDPD+VLN MFDEDHDELVLVK+IPMYSTCEHHLV+FHGVAHVGYIPG+DGRVTGLSKIA
Sbjct  61   TDPDAVLNAMFDEDHDELVLVKQIPMYSTCEHHLVSFHGVAHVGYIPGEDGRVTGLSKIA  120

Query  121  RLVDLYAKRPQVQERLTSQIADALMKKLDPRGVIVVIEAEHLCMAMRGVRKPGSVTTTSA  180
            RLVDLYAKRPQVQERLTSQIADAL+KKL+PRGVIVV+EAEHLCMAMRGVRKPG++TTTSA
Sbjct  121  RLVDLYAKRPQVQERLTSQIADALVKKLEPRGVIVVVEAEHLCMAMRGVRKPGAITTTSA  180

Query  181  VRGLFKTNAASRAEALDLILRK  202
            VRG FKTNAASRAEALDLILRK
Sbjct  181  VRGQFKTNAASRAEALDLILRK  202


>gi|183985080|ref|YP_001853371.1| GTP cyclohydrolase I FolE [Mycobacterium marinum M]
 gi|229487978|sp|B2HJ53.1|GCH1_MYCMM RecName: Full=GTP cyclohydrolase 1; AltName: Full=GTP cyclohydrolase 
I; Short=GTP-CH-I
 gi|183178406|gb|ACC43516.1| GTP cyclohydrolase I FolE [Mycobacterium marinum M]
Length=202

 Score =  360 bits (924),  Expect = 6e-98, Method: Compositional matrix adjust.
 Identities = 174/202 (87%), Positives = 189/202 (94%), Gaps = 0/202 (0%)

Query  1    MSQLDSRSASARIRVFDQQRAEAAVRELLYAIGEDPDRDGLVATPSRVARSYREMFAGLY  60
            M+QLDSR+ +   R FDQ RAEAAVRELL AIGEDPDR GL  TP+RVAR+YRE+FAGLY
Sbjct  1    MTQLDSRTEATTTRAFDQPRAEAAVRELLLAIGEDPDRGGLRDTPARVARAYREIFAGLY  60

Query  61   TDPDSVLNTMFDEDHDELVLVKEIPMYSTCEHHLVAFHGVAHVGYIPGDDGRVTGLSKIA  120
            TDPD+VLNTMFDEDHDELVL+KEIP+YSTCEHHLV+FHGVAHVGYIPG DGRVTGLSKIA
Sbjct  61   TDPDAVLNTMFDEDHDELVLIKEIPLYSTCEHHLVSFHGVAHVGYIPGRDGRVTGLSKIA  120

Query  121  RLVDLYAKRPQVQERLTSQIADALMKKLDPRGVIVVIEAEHLCMAMRGVRKPGSVTTTSA  180
            RLVDLYAKRPQVQERLTSQIADAL+K+L PRGVIVV+EAEHLCMAMRGVRKPG+VTTTSA
Sbjct  121  RLVDLYAKRPQVQERLTSQIADALVKRLGPRGVIVVVEAEHLCMAMRGVRKPGAVTTTSA  180

Query  181  VRGLFKTNAASRAEALDLILRK  202
            VRG FKT+AASRAEALDLILRK
Sbjct  181  VRGQFKTDAASRAEALDLILRK  202


>gi|254822682|ref|ZP_05227683.1| GTP cyclohydrolase I [Mycobacterium intracellulare ATCC 13950]
Length=190

 Score =  360 bits (923),  Expect = 8e-98, Method: Compositional matrix adjust.
 Identities = 173/190 (92%), Positives = 184/190 (97%), Gaps = 0/190 (0%)

Query  13   IRVFDQQRAEAAVRELLYAIGEDPDRDGLVATPSRVARSYREMFAGLYTDPDSVLNTMFD  72
            +RVFDQ RAEAAVRELL AIGEDPDR GL  TP+RVAR+YREMFAGLYTDPDSVLNTMFD
Sbjct  1    MRVFDQDRAEAAVRELLCAIGEDPDRHGLRETPARVARAYREMFAGLYTDPDSVLNTMFD  60

Query  73   EDHDELVLVKEIPMYSTCEHHLVAFHGVAHVGYIPGDDGRVTGLSKIARLVDLYAKRPQV  132
            EDHDELVLVKEIP+YSTCEHHLV+FHGVAHVGYIPG+DGRVTGLSKIARLVDLYAKRPQV
Sbjct  61   EDHDELVLVKEIPLYSTCEHHLVSFHGVAHVGYIPGNDGRVTGLSKIARLVDLYAKRPQV  120

Query  133  QERLTSQIADALMKKLDPRGVIVVIEAEHLCMAMRGVRKPGSVTTTSAVRGLFKTNAASR  192
            QERLTSQIADAL+KKL+PRGVIVV+EAEHLCMAMRGVRKPG+ TTTSAVRG+FKTNAASR
Sbjct  121  QERLTSQIADALVKKLNPRGVIVVVEAEHLCMAMRGVRKPGATTTTSAVRGIFKTNAASR  180

Query  193  AEALDLILRK  202
            AEALDLILRK
Sbjct  181  AEALDLILRK  190


>gi|118619365|ref|YP_907697.1| GTP cyclohydrolase I [Mycobacterium ulcerans Agy99]
 gi|229487979|sp|A0PV57.1|GCH1_MYCUA RecName: Full=GTP cyclohydrolase 1; AltName: Full=GTP cyclohydrolase 
I; Short=GTP-CH-I
 gi|118571475|gb|ABL06226.1| GTP cyclohydrolase I FolE [Mycobacterium ulcerans Agy99]
Length=202

 Score =  359 bits (922),  Expect = 1e-97, Method: Compositional matrix adjust.
 Identities = 173/202 (86%), Positives = 189/202 (94%), Gaps = 0/202 (0%)

Query  1    MSQLDSRSASARIRVFDQQRAEAAVRELLYAIGEDPDRDGLVATPSRVARSYREMFAGLY  60
            M+QLDSR+ +   R FDQ RAEAAVRELL AIGEDPDR GL  TP+RVAR+YRE+FAGLY
Sbjct  1    MTQLDSRTEATTTRAFDQPRAEAAVRELLLAIGEDPDRGGLRDTPARVARAYREIFAGLY  60

Query  61   TDPDSVLNTMFDEDHDELVLVKEIPMYSTCEHHLVAFHGVAHVGYIPGDDGRVTGLSKIA  120
            TDPD+VLNTMFDEDHDELVL+KEIP+YSTCEHHLV+FHGVAHVGYIPG DGRVTGLSKIA
Sbjct  61   TDPDAVLNTMFDEDHDELVLIKEIPLYSTCEHHLVSFHGVAHVGYIPGRDGRVTGLSKIA  120

Query  121  RLVDLYAKRPQVQERLTSQIADALMKKLDPRGVIVVIEAEHLCMAMRGVRKPGSVTTTSA  180
            RLVDLYAKRPQVQERLTSQIADAL+K+L PRGV+VV+EAEHLCMAMRGVRKPG+VTTTSA
Sbjct  121  RLVDLYAKRPQVQERLTSQIADALVKRLGPRGVLVVVEAEHLCMAMRGVRKPGAVTTTSA  180

Query  181  VRGLFKTNAASRAEALDLILRK  202
            VRG FKT+AASRAEALDLILRK
Sbjct  181  VRGQFKTDAASRAEALDLILRK  202


>gi|15827020|ref|NP_301283.1| GTP cyclohydrolase I [Mycobacterium leprae TN]
 gi|221229498|ref|YP_002502914.1| GTP cyclohydrolase I [Mycobacterium leprae Br4923]
 gi|6016112|sp|O69531.1|GCH1_MYCLE RecName: Full=GTP cyclohydrolase 1; AltName: Full=GTP cyclohydrolase 
I; Short=GTP-CH-I
 gi|254791047|sp|B8ZU42.1|GCH1_MYCLB RecName: Full=GTP cyclohydrolase 1; AltName: Full=GTP cyclohydrolase 
I; Short=GTP-CH-I
 gi|3097224|emb|CAA18795.1| GTP cyclohydrolase I [Mycobacterium leprae]
 gi|13092567|emb|CAC29731.1| putative GTP cyclohydrolase I [Mycobacterium leprae]
 gi|219932605|emb|CAR70316.1| putative GTP cyclohydrolase I [Mycobacterium leprae Br4923]
Length=205

 Score =  351 bits (900),  Expect = 4e-95, Method: Compositional matrix adjust.
 Identities = 165/195 (85%), Positives = 185/195 (95%), Gaps = 0/195 (0%)

Query  8    SASARIRVFDQQRAEAAVRELLYAIGEDPDRDGLVATPSRVARSYREMFAGLYTDPDSVL  67
            +A  RIRVFDQQRAEAA+RELLYAIGEDPDR+GL  TP+RVAR+ RE+F+GLYTDP +VL
Sbjct  11   TAVPRIRVFDQQRAEAAIRELLYAIGEDPDREGLADTPARVARACRELFSGLYTDPQTVL  70

Query  68   NTMFDEDHDELVLVKEIPMYSTCEHHLVAFHGVAHVGYIPGDDGRVTGLSKIARLVDLYA  127
            NTMFDE+H+ELV+VKEIPMYSTCEHHLV+FHGVAH+GY+PG DGRVTGLSKIARLVDLYA
Sbjct  71   NTMFDEEHNELVIVKEIPMYSTCEHHLVSFHGVAHIGYLPGADGRVTGLSKIARLVDLYA  130

Query  128  KRPQVQERLTSQIADALMKKLDPRGVIVVIEAEHLCMAMRGVRKPGSVTTTSAVRGLFKT  187
            KRPQVQERLTSQIADAL+ KLDPRGVI+V+EAEHLCMAMRGVRKPG++TTTSAVRG FKT
Sbjct  131  KRPQVQERLTSQIADALVSKLDPRGVIIVVEAEHLCMAMRGVRKPGAITTTSAVRGQFKT  190

Query  188  NAASRAEALDLILRK  202
            +AASRAEAL LILRK
Sbjct  191  DAASRAEALGLILRK  205


>gi|108801732|ref|YP_641929.1| GTP cyclohydrolase I [Mycobacterium sp. MCS]
 gi|119870883|ref|YP_940835.1| GTP cyclohydrolase I [Mycobacterium sp. KMS]
 gi|108772151|gb|ABG10873.1| GTP cyclohydrolase I [Mycobacterium sp. MCS]
 gi|119696972|gb|ABL94045.1| GTP cyclohydrolase I [Mycobacterium sp. KMS]
Length=201

 Score =  345 bits (884),  Expect = 3e-93, Method: Compositional matrix adjust.
 Identities = 166/195 (86%), Positives = 181/195 (93%), Gaps = 0/195 (0%)

Query  8    SASARIRVFDQQRAEAAVRELLYAIGEDPDRDGLVATPSRVARSYREMFAGLYTDPDSVL  67
            SA+ +I  FDQ RAEAAVRELL AIGEDPDR GLV TP+RVAR+YREMFAGLYTDPD VL
Sbjct  7    SATVKIADFDQPRAEAAVRELLIAIGEDPDRHGLVDTPARVARAYREMFAGLYTDPDDVL  66

Query  68   NTMFDEDHDELVLVKEIPMYSTCEHHLVAFHGVAHVGYIPGDDGRVTGLSKIARLVDLYA  127
            NT FDE HDE+VLVK+IPMYSTCEHHLVAFHGVAHVGYIPG DGRVTGLSK+AR+VDLYA
Sbjct  67   NTTFDEQHDEMVLVKDIPMYSTCEHHLVAFHGVAHVGYIPGVDGRVTGLSKLARVVDLYA  126

Query  128  KRPQVQERLTSQIADALMKKLDPRGVIVVIEAEHLCMAMRGVRKPGSVTTTSAVRGLFKT  187
            KRPQVQERLT+Q+ADALM+KLDPRGVIVV+EAEHLCMAMRG+RKPG+ TTTSAVRG FKT
Sbjct  127  KRPQVQERLTAQVADALMRKLDPRGVIVVMEAEHLCMAMRGIRKPGATTTTSAVRGQFKT  186

Query  188  NAASRAEALDLILRK  202
            + ASRAEALDLILRK
Sbjct  187  DKASRAEALDLILRK  201


>gi|145222009|ref|YP_001132687.1| GTP cyclohydrolase I [Mycobacterium gilvum PYR-GCK]
 gi|189045191|sp|A4T5P2.1|GCH1_MYCGI RecName: Full=GTP cyclohydrolase 1; AltName: Full=GTP cyclohydrolase 
I; Short=GTP-CH-I
 gi|145214495|gb|ABP43899.1| GTP cyclohydrolase I [Mycobacterium gilvum PYR-GCK]
Length=202

 Score =  343 bits (881),  Expect = 6e-93, Method: Compositional matrix adjust.
 Identities = 166/202 (83%), Positives = 184/202 (92%), Gaps = 0/202 (0%)

Query  1    MSQLDSRSASARIRVFDQQRAEAAVRELLYAIGEDPDRDGLVATPSRVARSYREMFAGLY  60
            M++  + SA+     FDQ RAEAAVRELL A+GEDPDR+GL+ TP+RVARSYRE+FAGLY
Sbjct  1    MTRSHNHSATLTTPDFDQARAEAAVRELLIAVGEDPDREGLLDTPARVARSYREIFAGLY  60

Query  61   TDPDSVLNTMFDEDHDELVLVKEIPMYSTCEHHLVAFHGVAHVGYIPGDDGRVTGLSKIA  120
            TDPD VL TMFDE HDE+VLVK+IPMYSTCEHHLV+FHGVAHVGYIPG DGRVTGLSK+A
Sbjct  61   TDPDEVLTTMFDEQHDEMVLVKDIPMYSTCEHHLVSFHGVAHVGYIPGVDGRVTGLSKLA  120

Query  121  RLVDLYAKRPQVQERLTSQIADALMKKLDPRGVIVVIEAEHLCMAMRGVRKPGSVTTTSA  180
            R+VDLYAKRPQVQERLTSQIADALM+KLDPRG IVVIEAEHLCMAMRG+RKPG+VTTTSA
Sbjct  121  RVVDLYAKRPQVQERLTSQIADALMRKLDPRGAIVVIEAEHLCMAMRGIRKPGAVTTTSA  180

Query  181  VRGLFKTNAASRAEALDLILRK  202
            VRG FKT+ ASRAEALDLILRK
Sbjct  181  VRGQFKTDKASRAEALDLILRK  202


>gi|126437719|ref|YP_001073410.1| GTP cyclohydrolase I [Mycobacterium sp. JLS]
 gi|126237519|gb|ABO00920.1| GTP cyclohydrolase I [Mycobacterium sp. JLS]
Length=201

 Score =  343 bits (880),  Expect = 9e-93, Method: Compositional matrix adjust.
 Identities = 166/195 (86%), Positives = 180/195 (93%), Gaps = 0/195 (0%)

Query  8    SASARIRVFDQQRAEAAVRELLYAIGEDPDRDGLVATPSRVARSYREMFAGLYTDPDSVL  67
            SA  +I  FDQ RAEAAVRELL AIGEDPDR GLV TP+RVAR+YREMFAGLYTDPD VL
Sbjct  7    SALVKIADFDQPRAEAAVRELLIAIGEDPDRHGLVDTPARVARAYREMFAGLYTDPDDVL  66

Query  68   NTMFDEDHDELVLVKEIPMYSTCEHHLVAFHGVAHVGYIPGDDGRVTGLSKIARLVDLYA  127
            NT FDE HDE+VLVK+IPMYSTCEHHLVAFHGVAHVGYIPG DGRVTGLSK+AR+VDLYA
Sbjct  67   NTTFDEQHDEMVLVKDIPMYSTCEHHLVAFHGVAHVGYIPGVDGRVTGLSKLARVVDLYA  126

Query  128  KRPQVQERLTSQIADALMKKLDPRGVIVVIEAEHLCMAMRGVRKPGSVTTTSAVRGLFKT  187
            KRPQVQERLT+Q+ADALM+KLDPRGVIVV+EAEHLCMAMRG+RKPG+ TTTSAVRG FKT
Sbjct  127  KRPQVQERLTAQVADALMRKLDPRGVIVVMEAEHLCMAMRGIRKPGATTTTSAVRGQFKT  186

Query  188  NAASRAEALDLILRK  202
            + ASRAEALDLILRK
Sbjct  187  DKASRAEALDLILRK  201


>gi|118473408|ref|YP_890325.1| GTP cyclohydrolase I [Mycobacterium smegmatis str. MC2 155]
 gi|118174695|gb|ABK75591.1| GTP cyclohydrolase I [Mycobacterium smegmatis str. MC2 155]
Length=203

 Score =  342 bits (878),  Expect = 1e-92, Method: Compositional matrix adjust.
 Identities = 164/189 (87%), Positives = 180/189 (96%), Gaps = 0/189 (0%)

Query  14   RVFDQQRAEAAVRELLYAIGEDPDRDGLVATPSRVARSYREMFAGLYTDPDSVLNTMFDE  73
            RVFDQ RAEAAVRELL AIGEDP+R+GLV TP+RVAR+Y+E+ AGL+TDPDSVLNT FDE
Sbjct  15   RVFDQPRAEAAVRELLIAIGEDPEREGLVDTPARVARAYKELMAGLHTDPDSVLNTTFDE  74

Query  74   DHDELVLVKEIPMYSTCEHHLVAFHGVAHVGYIPGDDGRVTGLSKIARLVDLYAKRPQVQ  133
             HDELVLVK+IPMYSTCEHHLV+FHGVAHVGYIPG DGRVTGLSKIARLVDLY+KRPQVQ
Sbjct  75   GHDELVLVKQIPMYSTCEHHLVSFHGVAHVGYIPGVDGRVTGLSKIARLVDLYSKRPQVQ  134

Query  134  ERLTSQIADALMKKLDPRGVIVVIEAEHLCMAMRGVRKPGSVTTTSAVRGLFKTNAASRA  193
            ERLT+QIADALM+KLDPRGVIVV+EAEHLCMAMRGVRKPG+VTTTSAVRG FKT+ ASRA
Sbjct  135  ERLTAQIADALMRKLDPRGVIVVVEAEHLCMAMRGVRKPGAVTTTSAVRGQFKTDKASRA  194

Query  194  EALDLILRK  202
            EAL+LILRK
Sbjct  195  EALELILRK  203


>gi|315446251|ref|YP_004079130.1| GTP cyclohydrolase I [Mycobacterium sp. Spyr1]
 gi|315264554|gb|ADU01296.1| GTP cyclohydrolase I [Mycobacterium sp. Spyr1]
Length=202

 Score =  341 bits (874),  Expect = 4e-92, Method: Compositional matrix adjust.
 Identities = 165/202 (82%), Positives = 183/202 (91%), Gaps = 0/202 (0%)

Query  1    MSQLDSRSASARIRVFDQQRAEAAVRELLYAIGEDPDRDGLVATPSRVARSYREMFAGLY  60
            M++  + SA+     FDQ RAEAAVRELL A+GEDPDR+GL  TP+RVARSYRE+FAGLY
Sbjct  1    MTRSHNHSATLTTPDFDQARAEAAVRELLIAVGEDPDREGLRDTPARVARSYREIFAGLY  60

Query  61   TDPDSVLNTMFDEDHDELVLVKEIPMYSTCEHHLVAFHGVAHVGYIPGDDGRVTGLSKIA  120
            TDPD VL TMFDE HDE+VLVK+IPMYSTCEHHLV+FHGVAHVGYIPG DGRVTGLSK+A
Sbjct  61   TDPDEVLTTMFDEQHDEMVLVKDIPMYSTCEHHLVSFHGVAHVGYIPGVDGRVTGLSKLA  120

Query  121  RLVDLYAKRPQVQERLTSQIADALMKKLDPRGVIVVIEAEHLCMAMRGVRKPGSVTTTSA  180
            R+VDLYAKRPQVQERLT+QIADALM+KLDPRG IVVIEAEHLCMAMRG+RKPG+VTTTSA
Sbjct  121  RVVDLYAKRPQVQERLTAQIADALMRKLDPRGAIVVIEAEHLCMAMRGIRKPGAVTTTSA  180

Query  181  VRGLFKTNAASRAEALDLILRK  202
            VRG FKT+ ASRAEALDLILRK
Sbjct  181  VRGQFKTDKASRAEALDLILRK  202


>gi|120406319|ref|YP_956148.1| GTP cyclohydrolase I [Mycobacterium vanbaalenii PYR-1]
 gi|166220278|sp|A1TG42.1|GCH1_MYCVP RecName: Full=GTP cyclohydrolase 1; AltName: Full=GTP cyclohydrolase 
I; Short=GTP-CH-I
 gi|119959137|gb|ABM16142.1| GTP cyclohydrolase I [Mycobacterium vanbaalenii PYR-1]
Length=202

 Score =  339 bits (869),  Expect = 2e-91, Method: Compositional matrix adjust.
 Identities = 163/202 (81%), Positives = 183/202 (91%), Gaps = 0/202 (0%)

Query  1    MSQLDSRSASARIRVFDQQRAEAAVRELLYAIGEDPDRDGLVATPSRVARSYREMFAGLY  60
            M++  + SA+     FDQ RAEAAVRELL A+GEDPDR+GL  TP+RVAR+Y+E+FAGLY
Sbjct  1    MTRSHNHSATITTARFDQARAEAAVRELLIAVGEDPDREGLRDTPARVARAYQEIFAGLY  60

Query  61   TDPDSVLNTMFDEDHDELVLVKEIPMYSTCEHHLVAFHGVAHVGYIPGDDGRVTGLSKIA  120
            TDPD VL TMFDE HDE+VLVK+IPMYSTCEHHLV+FHGVAHVGYIPG DGRVTGLSK+A
Sbjct  61   TDPDEVLKTMFDEQHDEMVLVKDIPMYSTCEHHLVSFHGVAHVGYIPGVDGRVTGLSKLA  120

Query  121  RLVDLYAKRPQVQERLTSQIADALMKKLDPRGVIVVIEAEHLCMAMRGVRKPGSVTTTSA  180
            R+VDLYAKRPQVQERLT QIADALM++LDPRGVIVVIEAEHLCMAMRG+RKPG+VTTTSA
Sbjct  121  RVVDLYAKRPQVQERLTGQIADALMRRLDPRGVIVVIEAEHLCMAMRGIRKPGAVTTTSA  180

Query  181  VRGLFKTNAASRAEALDLILRK  202
            VRG FKT+ ASRAEALDLILRK
Sbjct  181  VRGQFKTDKASRAEALDLILRK  202


>gi|333992538|ref|YP_004525152.1| GTP cyclohydrolase I FolE [Mycobacterium sp. JDM601]
 gi|333488506|gb|AEF37898.1| GTP cyclohydrolase I FolE [Mycobacterium sp. JDM601]
Length=196

 Score =  338 bits (868),  Expect = 2e-91, Method: Compositional matrix adjust.
 Identities = 157/187 (84%), Positives = 178/187 (96%), Gaps = 0/187 (0%)

Query  16   FDQQRAEAAVRELLYAIGEDPDRDGLVATPSRVARSYREMFAGLYTDPDSVLNTMFDEDH  75
            FDQ RAEAAVRELLYA+GEDPDR GLV TP+RVAR+Y+EMFAGLYTDPD+VL T FDE H
Sbjct  10   FDQARAEAAVRELLYAVGEDPDRAGLVDTPARVARAYQEMFAGLYTDPDTVLETTFDEQH  69

Query  76   DELVLVKEIPMYSTCEHHLVAFHGVAHVGYIPGDDGRVTGLSKIARLVDLYAKRPQVQER  135
            DE+VLVKEIP+YSTCEHHLV+FHGVAHVGYIPGDDGR+TGLSK+AR+VDLYAKRPQVQER
Sbjct  70   DEMVLVKEIPLYSTCEHHLVSFHGVAHVGYIPGDDGRITGLSKLARVVDLYAKRPQVQER  129

Query  136  LTSQIADALMKKLDPRGVIVVIEAEHLCMAMRGVRKPGSVTTTSAVRGLFKTNAASRAEA  195
            LT Q+ADALM+KL+PRGVIVV+EAEHLCMAMRGVRKPG++TTTSAVRG FK+++ASRAEA
Sbjct  130  LTGQVADALMRKLNPRGVIVVVEAEHLCMAMRGVRKPGAITTTSAVRGQFKSDSASRAEA  189

Query  196  LDLILRK  202
            L+LI RK
Sbjct  190  LELIRRK  196


>gi|343924377|ref|ZP_08763927.1| GTP cyclohydrolase I [Gordonia alkanivorans NBRC 16433]
 gi|343765709|dbj|GAA10853.1| GTP cyclohydrolase I [Gordonia alkanivorans NBRC 16433]
Length=203

 Score =  337 bits (864),  Expect = 7e-91, Method: Compositional matrix adjust.
 Identities = 160/186 (87%), Positives = 173/186 (94%), Gaps = 0/186 (0%)

Query  16   FDQQRAEAAVRELLYAIGEDPDRDGLVATPSRVARSYREMFAGLYTDPDSVLNTMFDEDH  75
            FDQ RAEAAVRELL AIGEDPDR+GLV TP+RVA +YREMFAGLYTDPD VL T FDEDH
Sbjct  18   FDQARAEAAVRELLLAIGEDPDREGLVRTPTRVANAYREMFAGLYTDPDEVLATTFDEDH  77

Query  76   DELVLVKEIPMYSTCEHHLVAFHGVAHVGYIPGDDGRVTGLSKIARLVDLYAKRPQVQER  135
            DELVLVK+IPMYSTCEHHLV+FHGVAHVGYIPG  GRVTGLSK+ARLVDLYAKRPQVQER
Sbjct  78   DELVLVKDIPMYSTCEHHLVSFHGVAHVGYIPGTSGRVTGLSKLARLVDLYAKRPQVQER  137

Query  136  LTSQIADALMKKLDPRGVIVVIEAEHLCMAMRGVRKPGSVTTTSAVRGLFKTNAASRAEA  195
            LTSQIADA+M+KL+PRGVIVVIEAEHLCMAMRG+RKPG+ TTTSAVRG+FKT+A SR EA
Sbjct  138  LTSQIADAVMRKLEPRGVIVVIEAEHLCMAMRGIRKPGATTTTSAVRGIFKTSAVSRGEA  197

Query  196  LDLILR  201
            LDLI R
Sbjct  198  LDLITR  203


>gi|325675046|ref|ZP_08154733.1| GTP cyclohydrolase I [Rhodococcus equi ATCC 33707]
 gi|325554632|gb|EGD24307.1| GTP cyclohydrolase I [Rhodococcus equi ATCC 33707]
Length=205

 Score =  336 bits (862),  Expect = 1e-90, Method: Compositional matrix adjust.
 Identities = 164/203 (81%), Positives = 183/203 (91%), Gaps = 1/203 (0%)

Query  1    MSQLDSRS-ASARIRVFDQQRAEAAVRELLYAIGEDPDRDGLVATPSRVARSYREMFAGL  59
            ++QL S S A A  R FDQ RAEAAVRELL A+GEDPDR GL+ TP+RVAR+YRE+FAGL
Sbjct  3    VNQLGSESVALATGRPFDQARAEAAVRELLLAVGEDPDRPGLLDTPARVARAYREVFAGL  62

Query  60   YTDPDSVLNTMFDEDHDELVLVKEIPMYSTCEHHLVAFHGVAHVGYIPGDDGRVTGLSKI  119
            YT+PD VLNT FDE H ELVLV++IPMYSTCEHHLV+FHGVAHVGYIPG +GRVTGLSK+
Sbjct  63   YTNPDDVLNTTFDEGHQELVLVRDIPMYSTCEHHLVSFHGVAHVGYIPGPEGRVTGLSKL  122

Query  120  ARLVDLYAKRPQVQERLTSQIADALMKKLDPRGVIVVIEAEHLCMAMRGVRKPGSVTTTS  179
            ARLVDLYAKRPQVQERLTSQIADALM KL PRG IVV+EAEHLCMAMRG+RKPG+ TTTS
Sbjct  123  ARLVDLYAKRPQVQERLTSQIADALMAKLAPRGAIVVVEAEHLCMAMRGIRKPGASTTTS  182

Query  180  AVRGLFKTNAASRAEALDLILRK  202
            AVRGLF++N+ASRAEALDLILRK
Sbjct  183  AVRGLFQSNSASRAEALDLILRK  205


>gi|312138053|ref|YP_004005389.1| gtp cyclohydrolase i [Rhodococcus equi 103S]
 gi|311887392|emb|CBH46704.1| GTP cyclohydrolase I [Rhodococcus equi 103S]
Length=219

 Score =  335 bits (860),  Expect = 2e-90, Method: Compositional matrix adjust.
 Identities = 164/203 (81%), Positives = 183/203 (91%), Gaps = 1/203 (0%)

Query  1    MSQLDSRS-ASARIRVFDQQRAEAAVRELLYAIGEDPDRDGLVATPSRVARSYREMFAGL  59
            ++QL S S A A  R FDQ RAEAAVRELL A+GEDPDR GL+ TP+RVAR+YRE+FAGL
Sbjct  17   VNQLGSESVALATGRPFDQARAEAAVRELLLAVGEDPDRPGLLDTPARVARAYREVFAGL  76

Query  60   YTDPDSVLNTMFDEDHDELVLVKEIPMYSTCEHHLVAFHGVAHVGYIPGDDGRVTGLSKI  119
            YT+PD VLNT FDE H ELVLV++IPMYSTCEHHLV+FHGVAHVGYIPG +GRVTGLSK+
Sbjct  77   YTNPDDVLNTTFDEGHQELVLVRDIPMYSTCEHHLVSFHGVAHVGYIPGPEGRVTGLSKL  136

Query  120  ARLVDLYAKRPQVQERLTSQIADALMKKLDPRGVIVVIEAEHLCMAMRGVRKPGSVTTTS  179
            ARLVDLYAKRPQVQERLTSQIADALM KL PRG IVV+EAEHLCMAMRG+RKPG+ TTTS
Sbjct  137  ARLVDLYAKRPQVQERLTSQIADALMAKLAPRGAIVVVEAEHLCMAMRGIRKPGASTTTS  196

Query  180  AVRGLFKTNAASRAEALDLILRK  202
            AVRGLF++N+ASRAEALDLILRK
Sbjct  197  AVRGLFQSNSASRAEALDLILRK  219


>gi|169627638|ref|YP_001701287.1| GTP cyclohydrolase I [Mycobacterium abscessus ATCC 19977]
 gi|229487977|sp|B1MGU9.1|GCH1_MYCA9 RecName: Full=GTP cyclohydrolase 1; AltName: Full=GTP cyclohydrolase 
I; Short=GTP-CH-I
 gi|169239605|emb|CAM60633.1| GTP cyclohydrolase I (FolE) [Mycobacterium abscessus]
Length=204

 Score =  335 bits (858),  Expect = 3e-90, Method: Compositional matrix adjust.
 Identities = 159/187 (86%), Positives = 174/187 (94%), Gaps = 0/187 (0%)

Query  15   VFDQQRAEAAVRELLYAIGEDPDRDGLVATPSRVARSYREMFAGLYTDPDSVLNTMFDED  74
            VFDQ RAEAAVRELLYA+GEDPDR GL  TP+RVAR+YRE+FAGLYTDPD+VLNT FDE 
Sbjct  17   VFDQARAEAAVRELLYAVGEDPDRHGLADTPARVARAYREIFAGLYTDPDTVLNTTFDEQ  76

Query  75   HDELVLVKEIPMYSTCEHHLVAFHGVAHVGYIPGDDGRVTGLSKIARLVDLYAKRPQVQE  134
            HDELVLVK IPMYSTCEHHLV+FHGVAHVGYIPG  GRVTGLSKIARLVDLYAKRPQVQE
Sbjct  77   HDELVLVKSIPMYSTCEHHLVSFHGVAHVGYIPGQHGRVTGLSKIARLVDLYAKRPQVQE  136

Query  135  RLTSQIADALMKKLDPRGVIVVIEAEHLCMAMRGVRKPGSVTTTSAVRGLFKTNAASRAE  194
            RLT+QIADAL++KL+PRGVIVV+EAEHLCMAMRGVRKPG+ TTTSAVRG FK +AASRAE
Sbjct  137  RLTAQIADALVRKLEPRGVIVVVEAEHLCMAMRGVRKPGATTTTSAVRGQFKRDAASRAE  196

Query  195  ALDLILR  201
             LDL++R
Sbjct  197  VLDLMMR  203


>gi|111021380|ref|YP_704352.1| GTP cyclohydrolase I [Rhodococcus jostii RHA1]
 gi|110820910|gb|ABG96194.1| GTP cyclohydrolase I [Rhodococcus jostii RHA1]
Length=205

 Score =  333 bits (853),  Expect = 1e-89, Method: Compositional matrix adjust.
 Identities = 159/189 (85%), Positives = 176/189 (94%), Gaps = 0/189 (0%)

Query  14   RVFDQQRAEAAVRELLYAIGEDPDRDGLVATPSRVARSYREMFAGLYTDPDSVLNTMFDE  73
            RVFDQ RAEAAVRELL AIGEDPDR GL  TPSRVARSYRE+FAGLYTDPD+VLNT FDE
Sbjct  17   RVFDQPRAEAAVRELLIAIGEDPDRPGLRDTPSRVARSYREVFAGLYTDPDTVLNTTFDE  76

Query  74   DHDELVLVKEIPMYSTCEHHLVAFHGVAHVGYIPGDDGRVTGLSKIARLVDLYAKRPQVQ  133
             H ELVLV++IP+YSTCEHHLV+FHGVAHVGYIPG  G+VTGLSK+AR+VDLYAKRPQVQ
Sbjct  77   GHQELVLVRDIPLYSTCEHHLVSFHGVAHVGYIPGKTGKVTGLSKLARVVDLYAKRPQVQ  136

Query  134  ERLTSQIADALMKKLDPRGVIVVIEAEHLCMAMRGVRKPGSVTTTSAVRGLFKTNAASRA  193
            ERLTSQIADA+M+KLDPRG IVVIEAEHLCMAMRG+RKPG+ TTTSAVRGL +++AASR+
Sbjct  137  ERLTSQIADAVMRKLDPRGAIVVIEAEHLCMAMRGIRKPGASTTTSAVRGLLQSSAASRS  196

Query  194  EALDLILRK  202
            EALDLILRK
Sbjct  197  EALDLILRK  205


>gi|326384086|ref|ZP_08205769.1| GTP cyclohydrolase I [Gordonia neofelifaecis NRRL B-59395]
 gi|326197246|gb|EGD54437.1| GTP cyclohydrolase I [Gordonia neofelifaecis NRRL B-59395]
Length=222

 Score =  332 bits (851),  Expect = 2e-89, Method: Compositional matrix adjust.
 Identities = 160/193 (83%), Positives = 178/193 (93%), Gaps = 0/193 (0%)

Query  9    ASARIRVFDQQRAEAAVRELLYAIGEDPDRDGLVATPSRVARSYREMFAGLYTDPDSVLN  68
            A+A  R+FDQ RAEAAVRELL A+GEDPDR GL  TP+RVA +YREMFAGLYTDPD VL 
Sbjct  30   AAAGDRLFDQARAEAAVRELLIAVGEDPDRAGLKRTPTRVANAYREMFAGLYTDPDEVLA  89

Query  69   TMFDEDHDELVLVKEIPMYSTCEHHLVAFHGVAHVGYIPGDDGRVTGLSKIARLVDLYAK  128
            T+FDEDH+ELVLVK+IPMYSTCEHHLV+FHGVAHVGYIPG+ G+VTGLSK+AR+VDLYAK
Sbjct  90   TVFDEDHEELVLVKDIPMYSTCEHHLVSFHGVAHVGYIPGETGQVTGLSKLARVVDLYAK  149

Query  129  RPQVQERLTSQIADALMKKLDPRGVIVVIEAEHLCMAMRGVRKPGSVTTTSAVRGLFKTN  188
            RPQVQERLTSQIADAL++KLDPRGVIVVIEAEHLCMAMRG+RKPG+ TTTSAVRGLFKT+
Sbjct  150  RPQVQERLTSQIADALVRKLDPRGVIVVIEAEHLCMAMRGIRKPGARTTTSAVRGLFKTS  209

Query  189  AASRAEALDLILR  201
            A SR EALDLI R
Sbjct  210  AVSRGEALDLITR  222


>gi|226363734|ref|YP_002781516.1| GTP cyclohydrolase I [Rhodococcus opacus B4]
 gi|226242223|dbj|BAH52571.1| GTP cyclohydrolase I [Rhodococcus opacus B4]
Length=203

 Score =  331 bits (848),  Expect = 4e-89, Method: Compositional matrix adjust.
 Identities = 158/189 (84%), Positives = 176/189 (94%), Gaps = 0/189 (0%)

Query  14   RVFDQQRAEAAVRELLYAIGEDPDRDGLVATPSRVARSYREMFAGLYTDPDSVLNTMFDE  73
            RVFDQ RAEAAVRELL AIGEDPDR GL  TP+RVARSYRE+FAGLYTDPD+VLNT FDE
Sbjct  15   RVFDQPRAEAAVRELLIAIGEDPDRPGLRDTPARVARSYREVFAGLYTDPDTVLNTTFDE  74

Query  74   DHDELVLVKEIPMYSTCEHHLVAFHGVAHVGYIPGDDGRVTGLSKIARLVDLYAKRPQVQ  133
             H ELVLV++IP+YSTCEHHLV+FHGVAHVGYIPG  G+VTGLSK+AR+VDLYAKRPQVQ
Sbjct  75   GHQELVLVRDIPLYSTCEHHLVSFHGVAHVGYIPGRTGKVTGLSKLARVVDLYAKRPQVQ  134

Query  134  ERLTSQIADALMKKLDPRGVIVVIEAEHLCMAMRGVRKPGSVTTTSAVRGLFKTNAASRA  193
            ERLTSQIADA+M+KLDPRG IVVIEAEHLCMAMRG+RKPG+ TTTSAVRGL +++AASR+
Sbjct  135  ERLTSQIADAVMRKLDPRGAIVVIEAEHLCMAMRGIRKPGASTTTSAVRGLLQSSAASRS  194

Query  194  EALDLILRK  202
            EALDLILRK
Sbjct  195  EALDLILRK  203


>gi|111026413|ref|YP_708696.1| GTP cyclohydrolase I [Rhodococcus jostii RHA1]
 gi|110825256|gb|ABH00538.1| GTP cyclohydrolase I [Rhodococcus jostii RHA1]
Length=203

 Score =  330 bits (847),  Expect = 6e-89, Method: Compositional matrix adjust.
 Identities = 155/189 (83%), Positives = 175/189 (93%), Gaps = 0/189 (0%)

Query  14   RVFDQQRAEAAVRELLYAIGEDPDRDGLVATPSRVARSYREMFAGLYTDPDSVLNTMFDE  73
            R FDQ RAEAAVRELL A+GEDPDR GLV TP+RVAR+Y+E+F GLYTDPDSVLNT FDE
Sbjct  15   RTFDQPRAEAAVRELLAAVGEDPDRPGLVDTPARVARAYKEIFGGLYTDPDSVLNTTFDE  74

Query  74   DHDELVLVKEIPMYSTCEHHLVAFHGVAHVGYIPGDDGRVTGLSKIARLVDLYAKRPQVQ  133
             H ELVLV++IPM+STCEHHLV+FHGVAHVGYIPG  G+VTGLSK+AR+VDLYAKRPQVQ
Sbjct  75   GHQELVLVRDIPMFSTCEHHLVSFHGVAHVGYIPGKSGKVTGLSKLARVVDLYAKRPQVQ  134

Query  134  ERLTSQIADALMKKLDPRGVIVVIEAEHLCMAMRGVRKPGSVTTTSAVRGLFKTNAASRA  193
            ERLTSQIADA+M+KLDPRG IVV+EAEHLCMAMRG+RKPG+ TTTSAVRGL +++AASRA
Sbjct  135  ERLTSQIADAVMRKLDPRGAIVVVEAEHLCMAMRGIRKPGASTTTSAVRGLLQSSAASRA  194

Query  194  EALDLILRK  202
            EALDLILRK
Sbjct  195  EALDLILRK  203


>gi|54022363|ref|YP_116605.1| GTP cyclohydrolase I [Nocardia farcinica IFM 10152]
 gi|54013871|dbj|BAD55241.1| putative GTP cyclohydrolase I [Nocardia farcinica IFM 10152]
Length=228

 Score =  329 bits (844),  Expect = 1e-88, Method: Compositional matrix adjust.
 Identities = 156/189 (83%), Positives = 174/189 (93%), Gaps = 0/189 (0%)

Query  14   RVFDQQRAEAAVRELLYAIGEDPDRDGLVATPSRVARSYREMFAGLYTDPDSVLNTMFDE  73
            R FDQ RAEAA+RELL A+GEDPDR GL+ TP+RVAR+YREMFAGLY +PD VL+T FDE
Sbjct  40   RPFDQPRAEAAIRELLIAVGEDPDRPGLIDTPARVARAYREMFAGLYVEPDRVLDTTFDE  99

Query  74   DHDELVLVKEIPMYSTCEHHLVAFHGVAHVGYIPGDDGRVTGLSKIARLVDLYAKRPQVQ  133
             H ELVLV++IPMYSTCEHHLV+FHGVAHVGYIPG  GRVTGLSK+ARLVDLYAKRPQVQ
Sbjct  100  GHQELVLVRDIPMYSTCEHHLVSFHGVAHVGYIPGPAGRVTGLSKLARLVDLYAKRPQVQ  159

Query  134  ERLTSQIADALMKKLDPRGVIVVIEAEHLCMAMRGVRKPGSVTTTSAVRGLFKTNAASRA  193
            ERLTSQIADA+M+KL+PRG IVV+EAEHLCMAMRG+RKPG+ TTTSAVRGL +TNAASRA
Sbjct  160  ERLTSQIADAVMRKLEPRGAIVVVEAEHLCMAMRGIRKPGASTTTSAVRGLLQTNAASRA  219

Query  194  EALDLILRK  202
            EALDLILRK
Sbjct  220  EALDLILRK  228


>gi|262203871|ref|YP_003275079.1| GTP cyclohydrolase I [Gordonia bronchialis DSM 43247]
 gi|262087218|gb|ACY23186.1| GTP cyclohydrolase I [Gordonia bronchialis DSM 43247]
Length=219

 Score =  328 bits (842),  Expect = 2e-88, Method: Compositional matrix adjust.
 Identities = 159/200 (80%), Positives = 178/200 (89%), Gaps = 1/200 (0%)

Query  2    SQLDSRSASARIRVFDQQRAEAAVRELLYAIGEDPDRDGLVATPSRVARSYREMFAGLYT  61
            + +D+R+   R   FDQ RAEAAVRELL A+GEDPDR GL+ TP+RVA +YREMFAGLYT
Sbjct  21   ADVDARAVPQRAG-FDQARAEAAVRELLLAVGEDPDRQGLLRTPTRVANAYREMFAGLYT  79

Query  62   DPDSVLNTMFDEDHDELVLVKEIPMYSTCEHHLVAFHGVAHVGYIPGDDGRVTGLSKIAR  121
            +PD VL T FDEDHDELVLVK+IPMYSTCEHHLV FHGVAHVGYIPG  G+VTGLSK+AR
Sbjct  80   EPDDVLATTFDEDHDELVLVKDIPMYSTCEHHLVPFHGVAHVGYIPGVSGQVTGLSKLAR  139

Query  122  LVDLYAKRPQVQERLTSQIADALMKKLDPRGVIVVIEAEHLCMAMRGVRKPGSVTTTSAV  181
            LVDLYAKRPQVQERLTSQIADA++++LDPRGVIVVIEAEHLCMAMRG+RKPG+ TTTSAV
Sbjct  140  LVDLYAKRPQVQERLTSQIADAIVRRLDPRGVIVVIEAEHLCMAMRGIRKPGATTTTSAV  199

Query  182  RGLFKTNAASRAEALDLILR  201
            RGLFKT+A SR EALDLI R
Sbjct  200  RGLFKTSAVSRGEALDLITR  219


>gi|333917990|ref|YP_004491571.1| GTP cyclohydrolase 1 [Amycolicicoccus subflavus DQS3-9A1]
 gi|333480211|gb|AEF38771.1| GTP cyclohydrolase 1 [Amycolicicoccus subflavus DQS3-9A1]
Length=209

 Score =  328 bits (841),  Expect = 3e-88, Method: Compositional matrix adjust.
 Identities = 155/189 (83%), Positives = 175/189 (93%), Gaps = 0/189 (0%)

Query  14   RVFDQQRAEAAVRELLYAIGEDPDRDGLVATPSRVARSYREMFAGLYTDPDSVLNTMFDE  73
            RVFDQ RAEAAVRELL A+GEDP R GL  TP+RVAR+Y E+FAGL+TDPD VL+T FDE
Sbjct  21   RVFDQPRAEAAVRELLIAVGEDPSRSGLADTPARVARAYAELFAGLHTDPDHVLDTTFDE  80

Query  74   DHDELVLVKEIPMYSTCEHHLVAFHGVAHVGYIPGDDGRVTGLSKIARLVDLYAKRPQVQ  133
             HDELVL+K+IPMYSTCEHHLV FHGVAHVGYIP + GRVTGLSK+ARLVDLYAK+PQVQ
Sbjct  81   GHDELVLLKDIPMYSTCEHHLVPFHGVAHVGYIPNESGRVTGLSKLARLVDLYAKQPQVQ  140

Query  134  ERLTSQIADALMKKLDPRGVIVVIEAEHLCMAMRGVRKPGSVTTTSAVRGLFKTNAASRA  193
            ERLTSQIADA+M+KLDPRGVIVV+EAEHLCMAMRG+RKPG+ TTTSAVRGLFK++AASR+
Sbjct  141  ERLTSQIADAMMRKLDPRGVIVVVEAEHLCMAMRGIRKPGATTTTSAVRGLFKSSAASRS  200

Query  194  EALDLILRK  202
            EALDLI+RK
Sbjct  201  EALDLIIRK  209


>gi|226304115|ref|YP_002764073.1| GTP cyclohydrolase I [Rhodococcus erythropolis PR4]
 gi|226183230|dbj|BAH31334.1| GTP cyclohydrolase I [Rhodococcus erythropolis PR4]
Length=205

 Score =  325 bits (833),  Expect = 2e-87, Method: Compositional matrix adjust.
 Identities = 152/189 (81%), Positives = 174/189 (93%), Gaps = 0/189 (0%)

Query  14   RVFDQQRAEAAVRELLYAIGEDPDRDGLVATPSRVARSYREMFAGLYTDPDSVLNTMFDE  73
            R FDQ RAEAAVRELL A+GEDP+R GL+ TP+RVARSY+E+FAGLY++PD  LNT FDE
Sbjct  17   RPFDQARAEAAVRELLIAVGEDPERPGLLDTPARVARSYKEIFAGLYSEPDDALNTTFDE  76

Query  74   DHDELVLVKEIPMYSTCEHHLVAFHGVAHVGYIPGDDGRVTGLSKIARLVDLYAKRPQVQ  133
             H ELVLV++IPM+STCEHHLV+FHGVAHVGYIPG  G+VTGLSK+AR+VDLYAKRPQVQ
Sbjct  77   GHQELVLVRDIPMFSTCEHHLVSFHGVAHVGYIPGKSGKVTGLSKLARVVDLYAKRPQVQ  136

Query  134  ERLTSQIADALMKKLDPRGVIVVIEAEHLCMAMRGVRKPGSVTTTSAVRGLFKTNAASRA  193
            ERLTSQIADALM+KLDPRG IVVIEAEHLCMAMRG+RKPG+ TTTSAVRGL +++AASR+
Sbjct  137  ERLTSQIADALMRKLDPRGAIVVIEAEHLCMAMRGIRKPGASTTTSAVRGLLQSSAASRS  196

Query  194  EALDLILRK  202
            EALDLILRK
Sbjct  197  EALDLILRK  205


>gi|229494246|ref|ZP_04388009.1| GTP cyclohydrolase I [Rhodococcus erythropolis SK121]
 gi|229318608|gb|EEN84466.1| GTP cyclohydrolase I [Rhodococcus erythropolis SK121]
Length=203

 Score =  325 bits (832),  Expect = 3e-87, Method: Compositional matrix adjust.
 Identities = 152/189 (81%), Positives = 174/189 (93%), Gaps = 0/189 (0%)

Query  14   RVFDQQRAEAAVRELLYAIGEDPDRDGLVATPSRVARSYREMFAGLYTDPDSVLNTMFDE  73
            R FDQ RAEAAVRELL A+GEDP+R GL+ TP+RVARSY+E+FAGLY++PD  LNT FDE
Sbjct  15   RPFDQARAEAAVRELLIAVGEDPERPGLLDTPARVARSYKEIFAGLYSEPDDALNTTFDE  74

Query  74   DHDELVLVKEIPMYSTCEHHLVAFHGVAHVGYIPGDDGRVTGLSKIARLVDLYAKRPQVQ  133
             H ELVLV++IPM+STCEHHLV+FHGVAHVGYIPG  G+VTGLSK+AR+VDLYAKRPQVQ
Sbjct  75   GHQELVLVRDIPMFSTCEHHLVSFHGVAHVGYIPGKSGKVTGLSKLARVVDLYAKRPQVQ  134

Query  134  ERLTSQIADALMKKLDPRGVIVVIEAEHLCMAMRGVRKPGSVTTTSAVRGLFKTNAASRA  193
            ERLTSQIADALM+KLDPRG IVVIEAEHLCMAMRG+RKPG+ TTTSAVRGL +++AASR+
Sbjct  135  ERLTSQIADALMRKLDPRGAIVVIEAEHLCMAMRGIRKPGASTTTSAVRGLLQSSAASRS  194

Query  194  EALDLILRK  202
            EALDLILRK
Sbjct  195  EALDLILRK  203


>gi|23429479|gb|AAM97307.1| GTP cyclohydrolase I [Nocardia iowensis]
Length=227

 Score =  324 bits (830),  Expect = 6e-87, Method: Compositional matrix adjust.
 Identities = 150/189 (80%), Positives = 173/189 (92%), Gaps = 0/189 (0%)

Query  14   RVFDQQRAEAAVRELLYAIGEDPDRDGLVATPSRVARSYREMFAGLYTDPDSVLNTMFDE  73
            R FDQ RAEAAVRELL A+GE+PDR GL+ TP+RVAR+YREMFAGLY +P+ VLNT FDE
Sbjct  39   RAFDQDRAEAAVRELLLAVGENPDRPGLIDTPARVARAYREMFAGLYVEPEDVLNTTFDE  98

Query  74   DHDELVLVKEIPMYSTCEHHLVAFHGVAHVGYIPGDDGRVTGLSKIARLVDLYAKRPQVQ  133
             H ELVLV++IP+YSTCEHHLV+FHGVAHVGYIPG  GRVTGLSK+ARLVDLYAKRPQVQ
Sbjct  99   GHQELVLVRDIPLYSTCEHHLVSFHGVAHVGYIPGKHGRVTGLSKLARLVDLYAKRPQVQ  158

Query  134  ERLTSQIADALMKKLDPRGVIVVIEAEHLCMAMRGVRKPGSVTTTSAVRGLFKTNAASRA  193
            ERLTSQ+ADA+M+KLDPRG IVV+EAEHLCMAMRG+RKPG+ TTTSAVRGL +++ +SR+
Sbjct  159  ERLTSQVADAVMRKLDPRGAIVVVEAEHLCMAMRGIRKPGASTTTSAVRGLLQSSPSSRS  218

Query  194  EALDLILRK  202
            EALDLILRK
Sbjct  219  EALDLILRK  227


>gi|226364783|ref|YP_002782565.1| GTP cyclohydrolase I [Rhodococcus opacus B4]
 gi|226243272|dbj|BAH53620.1| GTP cyclohydrolase I [Rhodococcus opacus B4]
Length=203

 Score =  317 bits (812),  Expect = 7e-85, Method: Compositional matrix adjust.
 Identities = 150/188 (80%), Positives = 170/188 (91%), Gaps = 0/188 (0%)

Query  15   VFDQQRAEAAVRELLYAIGEDPDRDGLVATPSRVARSYREMFAGLYTDPDSVLNTMFDED  74
            +FDQ RAEAAVRELL AIGEDPDR GL+ TP+RVARSYRE+FAGLYTDP  VL T FDE 
Sbjct  16   MFDQPRAEAAVRELLLAIGEDPDRPGLIDTPARVARSYREVFAGLYTDPAEVLGTTFDEG  75

Query  75   HDELVLVKEIPMYSTCEHHLVAFHGVAHVGYIPGDDGRVTGLSKIARLVDLYAKRPQVQE  134
            H ELVLV++IP+YSTCEHHLV+FHGVAHVGYIPG  G+VTGLSKIAR+VDLYAKRPQVQE
Sbjct  76   HRELVLVRDIPLYSTCEHHLVSFHGVAHVGYIPGSTGKVTGLSKIARVVDLYAKRPQVQE  135

Query  135  RLTSQIADALMKKLDPRGVIVVIEAEHLCMAMRGVRKPGSVTTTSAVRGLFKTNAASRAE  194
            RLTSQ+ADA+M+KL+PRG IVVIEAEHLCMAMRG+RKPG+ TTTSAVRG  +++AASR+E
Sbjct  136  RLTSQVADAVMRKLNPRGAIVVIEAEHLCMAMRGIRKPGASTTTSAVRGTLQSSAASRSE  195

Query  195  ALDLILRK  202
            AL LILR 
Sbjct  196  ALALILRN  203


>gi|296138296|ref|YP_003645539.1| GTP cyclohydrolase I [Tsukamurella paurometabola DSM 20162]
 gi|296026430|gb|ADG77200.1| GTP cyclohydrolase I [Tsukamurella paurometabola DSM 20162]
Length=198

 Score =  315 bits (807),  Expect = 2e-84, Method: Compositional matrix adjust.
 Identities = 150/193 (78%), Positives = 174/193 (91%), Gaps = 0/193 (0%)

Query  10   SARIRVFDQQRAEAAVRELLYAIGEDPDRDGLVATPSRVARSYREMFAGLYTDPDSVLNT  69
             A I  FD +RA AAVRELL A+GEDP+R+GL  TP RVAR+++E+F GL+TDPDSVL+T
Sbjct  6    GAAIAPFDHERAVAAVRELLIAVGEDPEREGLKKTPERVARAFQEVFGGLHTDPDSVLDT  65

Query  70   MFDEDHDELVLVKEIPMYSTCEHHLVAFHGVAHVGYIPGDDGRVTGLSKIARLVDLYAKR  129
             F EDHDELVLVK+IPMYSTCEHHLV+FHGVAHVGY+PG  GRVTGLSK+AR+VDLYAKR
Sbjct  66   TFGEDHDELVLVKDIPMYSTCEHHLVSFHGVAHVGYLPGPSGRVTGLSKLARVVDLYAKR  125

Query  130  PQVQERLTSQIADALMKKLDPRGVIVVIEAEHLCMAMRGVRKPGSVTTTSAVRGLFKTNA  189
            PQVQERLT+QIADA+++KLDPRGVIVVIEAEHLCMAMRG+RKPG+ TTTSAVRG FK +A
Sbjct  126  PQVQERLTAQIADAVVRKLDPRGVIVVIEAEHLCMAMRGIRKPGASTTTSAVRGAFKDSA  185

Query  190  ASRAEALDLILRK  202
             SRAEAL+LILR+
Sbjct  186  TSRAEALELILRR  198


>gi|256374469|ref|YP_003098129.1| GTP cyclohydrolase I [Actinosynnema mirum DSM 43827]
 gi|255918772|gb|ACU34283.1| GTP cyclohydrolase I [Actinosynnema mirum DSM 43827]
Length=209

 Score =  309 bits (791),  Expect = 2e-82, Method: Compositional matrix adjust.
 Identities = 146/195 (75%), Positives = 170/195 (88%), Gaps = 0/195 (0%)

Query  5    DSRSASARIRVFDQQRAEAAVRELLYAIGEDPDRDGLVATPSRVARSYREMFAGLYTDPD  64
            +  +  A  R FDQ+RAEAAVRELL A GEDP+R+GL  TP+RVAR+YREMFAGL+T+PD
Sbjct  12   NGEAGVAAKRPFDQERAEAAVRELLLACGEDPEREGLRETPARVARAYREMFAGLFTEPD  71

Query  65   SVLNTMFDEDHDELVLVKEIPMYSTCEHHLVAFHGVAHVGYIPGDDGRVTGLSKIARLVD  124
             VL   FDE H+ELVLV EIP+YS CEHHL+ FHGVAHVGYIP + GRVTGLSK+ARLVD
Sbjct  72   GVLAKTFDESHEELVLVTEIPVYSFCEHHLLPFHGVAHVGYIPNEQGRVTGLSKLARLVD  131

Query  125  LYAKRPQVQERLTSQIADALMKKLDPRGVIVVIEAEHLCMAMRGVRKPGSVTTTSAVRGL  184
            LYAKRPQVQERLTSQ+ADAL+++L+PRGVIVV+EAEHLCM MRGVRKPGS TTTSAVRGL
Sbjct  132  LYAKRPQVQERLTSQVADALVRRLEPRGVIVVVEAEHLCMGMRGVRKPGSRTTTSAVRGL  191

Query  185  FKTNAASRAEALDLI  199
             +T+A+SRAEA+ LI
Sbjct  192  LRTSASSRAEAISLI  206


>gi|302530788|ref|ZP_07283130.1| GTP cyclohydrolase I [Streptomyces sp. AA4]
 gi|302439683|gb|EFL11499.1| GTP cyclohydrolase I [Streptomyces sp. AA4]
Length=204

 Score =  306 bits (784),  Expect = 1e-81, Method: Compositional matrix adjust.
 Identities = 149/200 (75%), Positives = 172/200 (86%), Gaps = 1/200 (0%)

Query  1    MSQLDSRSASARIR-VFDQQRAEAAVRELLYAIGEDPDRDGLVATPSRVARSYREMFAGL  59
            M+  D  S+   IR VFDQ RAE AVRELL A GEDPDRDGL  TP+RVAR+Y+EMFAGL
Sbjct  1    MTSTDQTSSKDGIRPVFDQDRAERAVRELLLACGEDPDRDGLQDTPARVARAYQEMFAGL  60

Query  60   YTDPDSVLNTMFDEDHDELVLVKEIPMYSTCEHHLVAFHGVAHVGYIPGDDGRVTGLSKI  119
            YTDPD VL   FDE H+ELVLV +IPMYS CEHHL+ FHGVAHVGYIP  +G+VTGLSK+
Sbjct  61   YTDPDEVLARTFDESHEELVLVTDIPMYSNCEHHLLPFHGVAHVGYIPNGEGKVTGLSKL  120

Query  120  ARLVDLYAKRPQVQERLTSQIADALMKKLDPRGVIVVIEAEHLCMAMRGVRKPGSVTTTS  179
            ARLVDLYA+RPQVQERLTSQIADAL +KL+PRGVIVVIEAEHLCM++RG+RKPGS TTTS
Sbjct  121  ARLVDLYARRPQVQERLTSQIADALDRKLEPRGVIVVIEAEHLCMSVRGIRKPGSRTTTS  180

Query  180  AVRGLFKTNAASRAEALDLI  199
            AVRG+ +++A SRAEA++LI
Sbjct  181  AVRGMLRSSATSRAEAIELI  200


>gi|300790551|ref|YP_003770842.1| GTP cyclohydrolase I [Amycolatopsis mediterranei U32]
 gi|299800065|gb|ADJ50440.1| GTP cyclohydrolase I [Amycolatopsis mediterranei U32]
Length=204

 Score =  304 bits (778),  Expect = 5e-81, Method: Compositional matrix adjust.
 Identities = 148/200 (74%), Positives = 171/200 (86%), Gaps = 1/200 (0%)

Query  1    MSQLDSRSASARIR-VFDQQRAEAAVRELLYAIGEDPDRDGLVATPSRVARSYREMFAGL  59
            M+ +D  S S   R VFD  RAE A+RELL A GEDP+RDGL  TP+RVAR+Y+EMFAGL
Sbjct  1    MTWMDQTSHSDADRPVFDHDRAEKAIRELLLACGEDPERDGLKDTPARVARAYQEMFAGL  60

Query  60   YTDPDSVLNTMFDEDHDELVLVKEIPMYSTCEHHLVAFHGVAHVGYIPGDDGRVTGLSKI  119
            YT+PDSVL+  FDE H+ELVLV +IPM+S CEHHLV FHGVAHVGYIP   G+VTGLSK+
Sbjct  61   YTEPDSVLDRTFDESHEELVLVTDIPMFSQCEHHLVPFHGVAHVGYIPNAAGKVTGLSKL  120

Query  120  ARLVDLYAKRPQVQERLTSQIADALMKKLDPRGVIVVIEAEHLCMAMRGVRKPGSVTTTS  179
            ARLVDLYAKRPQVQERLTSQ+ADA+++KL+PRGVIVVIEAEHLCMAMRG+RKPG+ TTTS
Sbjct  121  ARLVDLYAKRPQVQERLTSQVADAIVRKLEPRGVIVVIEAEHLCMAMRGIRKPGARTTTS  180

Query  180  AVRGLFKTNAASRAEALDLI  199
            AVRG  K + +SRAEALDLI
Sbjct  181  AVRGQLKNSPSSRAEALDLI  200


>gi|340532238|gb|AEK47443.1| GTP cyclohydrolase I [Amycolatopsis mediterranei S699]
Length=201

 Score =  302 bits (773),  Expect = 2e-80, Method: Compositional matrix adjust.
 Identities = 143/185 (78%), Positives = 164/185 (89%), Gaps = 0/185 (0%)

Query  15   VFDQQRAEAAVRELLYAIGEDPDRDGLVATPSRVARSYREMFAGLYTDPDSVLNTMFDED  74
            VFD  RAE A+RELL A GEDP+RDGL  TP+RVAR+Y+EMFAGLYT+PDSVL+  FDE 
Sbjct  13   VFDHDRAEKAIRELLLACGEDPERDGLKDTPARVARAYQEMFAGLYTEPDSVLDRTFDES  72

Query  75   HDELVLVKEIPMYSTCEHHLVAFHGVAHVGYIPGDDGRVTGLSKIARLVDLYAKRPQVQE  134
            H+ELVLV +IPM+S CEHHLV FHGVAHVGYIP   G+VTGLSK+ARLVDLYAKRPQVQE
Sbjct  73   HEELVLVTDIPMFSQCEHHLVPFHGVAHVGYIPNAAGKVTGLSKLARLVDLYAKRPQVQE  132

Query  135  RLTSQIADALMKKLDPRGVIVVIEAEHLCMAMRGVRKPGSVTTTSAVRGLFKTNAASRAE  194
            RLTSQ+ADA+++KL+PRGVIVVIEAEHLCMAMRG+RKPG+ TTTSAVRG  K + +SRAE
Sbjct  133  RLTSQVADAIVRKLEPRGVIVVIEAEHLCMAMRGIRKPGARTTTSAVRGQLKNSPSSRAE  192

Query  195  ALDLI  199
            ALDLI
Sbjct  193  ALDLI  197


>gi|257057515|ref|YP_003135347.1| GTP cyclohydrolase I [Saccharomonospora viridis DSM 43017]
 gi|256587387|gb|ACU98520.1| GTP cyclohydrolase I [Saccharomonospora viridis DSM 43017]
Length=222

 Score =  301 bits (770),  Expect = 4e-80, Method: Compositional matrix adjust.
 Identities = 144/197 (74%), Positives = 169/197 (86%), Gaps = 0/197 (0%)

Query  3    QLDSRSASARIRVFDQQRAEAAVRELLYAIGEDPDRDGLVATPSRVARSYREMFAGLYTD  62
            ++D+    A   VFDQ+RAE AVRE L A GEDPDRDGL  TP+RVAR+YRE+FAGLY D
Sbjct  22   EVDAERPEAGHAVFDQERAERAVREFLLACGEDPDRDGLRETPARVARAYRELFAGLYCD  81

Query  63   PDSVLNTMFDEDHDELVLVKEIPMYSTCEHHLVAFHGVAHVGYIPGDDGRVTGLSKIARL  122
            PD VL+  FDE H+ELVLV +IP++S CEHHL+ FHGVAHVGYIP   G+VTGLSK+ARL
Sbjct  82   PDHVLDRTFDESHEELVLVTDIPIFSLCEHHLLPFHGVAHVGYIPNGQGKVTGLSKLARL  141

Query  123  VDLYAKRPQVQERLTSQIADALMKKLDPRGVIVVIEAEHLCMAMRGVRKPGSVTTTSAVR  182
            VD+YAKRPQVQERLTSQ+ADAL +KL PRGVIVV+EAEHLCM+MRGVRKPGS TTTSAVR
Sbjct  142  VDMYAKRPQVQERLTSQVADALNRKLRPRGVIVVVEAEHLCMSMRGVRKPGSRTTTSAVR  201

Query  183  GLFKTNAASRAEALDLI  199
            GL +++A+SRAEAL+LI
Sbjct  202  GLLQSSASSRAEALELI  218


>gi|38234565|ref|NP_940332.1| GTP cyclohydrolase I [Corynebacterium diphtheriae NCTC 13129]
 gi|38200828|emb|CAE50532.1| GTP cyclohydrolase I [Corynebacterium diphtheriae]
Length=190

 Score =  298 bits (764),  Expect = 2e-79, Method: Compositional matrix adjust.
 Identities = 141/184 (77%), Positives = 161/184 (88%), Gaps = 0/184 (0%)

Query  16   FDQQRAEAAVRELLYAIGEDPDRDGLVATPSRVARSYREMFAGLYTDPDSVLNTMFDEDH  75
            FDQQRAEAAVRELL A+GEDPDR+GL  TP+RVA++Y EMFAGL+TDP  VL   F EDH
Sbjct  5    FDQQRAEAAVRELLIAVGEDPDREGLQETPARVAKAYAEMFAGLHTDPTEVLAKTFSEDH  64

Query  76   DELVLVKEIPMYSTCEHHLVAFHGVAHVGYIPGDDGRVTGLSKIARLVDLYAKRPQVQER  135
             E+VLV++IP+YSTCEHHLV F G AH+GYIPG+ G+VTGLSK+ARLVDLYAKRPQVQER
Sbjct  65   REVVLVRDIPIYSTCEHHLVPFFGKAHIGYIPGESGKVTGLSKLARLVDLYAKRPQVQER  124

Query  136  LTSQIADALMKKLDPRGVIVVIEAEHLCMAMRGVRKPGSVTTTSAVRGLFKTNAASRAEA  195
            LT+Q+ADAL+ KL  + VIVVIE EHLCMAMRG+RKPG+VTTTSAVRG FKTNAASRAE 
Sbjct  125  LTTQVADALVDKLQAQAVIVVIECEHLCMAMRGIRKPGAVTTTSAVRGGFKTNAASRAEV  184

Query  196  LDLI  199
            L LI
Sbjct  185  LSLI  188


>gi|325000126|ref|ZP_08121238.1| GTP cyclohydrolase I [Pseudonocardia sp. P1]
Length=241

 Score =  298 bits (763),  Expect = 3e-79, Method: Compositional matrix adjust.
 Identities = 143/184 (78%), Positives = 164/184 (90%), Gaps = 0/184 (0%)

Query  16   FDQQRAEAAVRELLYAIGEDPDRDGLVATPSRVARSYREMFAGLYTDPDSVLNTMFDEDH  75
             D  RAE AVRELL A+GE+PDR+GL  TP+RVAR+Y E+FAGL+ DPDSVL   FDE H
Sbjct  55   IDLDRAERAVRELLIAVGENPDREGLKETPARVARAYGEIFAGLFVDPDSVLEKTFDEGH  114

Query  76   DELVLVKEIPMYSTCEHHLVAFHGVAHVGYIPGDDGRVTGLSKIARLVDLYAKRPQVQER  135
             ELVLVK+IPM+STCEHHLV FHGVAHVGYIP  DG+VTGLSKIAR+VDLYAKRPQVQER
Sbjct  115  GELVLVKDIPMFSTCEHHLVPFHGVAHVGYIPAVDGQVTGLSKIARVVDLYAKRPQVQER  174

Query  136  LTSQIADALMKKLDPRGVIVVIEAEHLCMAMRGVRKPGSVTTTSAVRGLFKTNAASRAEA  195
            LT+Q+ADAL++KL+PR VIVV+EAEHLCMAMRG+RKPGS TTTSAVRGLFK++A+SRAEA
Sbjct  175  LTAQVADALVRKLNPRAVIVVMEAEHLCMAMRGIRKPGSRTTTSAVRGLFKSSASSRAEA  234

Query  196  LDLI  199
            L LI
Sbjct  235  LSLI  238


>gi|25029097|ref|NP_739151.1| GTP cyclohydrolase I [Corynebacterium efficiens YS-314]
 gi|259505906|ref|ZP_05748808.1| GTP cyclohydrolase I [Corynebacterium efficiens YS-314]
 gi|41017200|sp|Q8FMG3.1|GCH1_COREF RecName: Full=GTP cyclohydrolase 1; AltName: Full=GTP cyclohydrolase 
I; Short=GTP-CH-I
 gi|23494384|dbj|BAC19351.1| putative GTP cyclohydrolase I [Corynebacterium efficiens YS-314]
 gi|259166510|gb|EEW51064.1| GTP cyclohydrolase I [Corynebacterium efficiens YS-314]
Length=197

 Score =  297 bits (760),  Expect = 6e-79, Method: Compositional matrix adjust.
 Identities = 139/187 (75%), Positives = 163/187 (88%), Gaps = 0/187 (0%)

Query  13   IRVFDQQRAEAAVRELLYAIGEDPDRDGLVATPSRVARSYREMFAGLYTDPDSVLNTMFD  72
            +R FDQ+RAEAAVRELL A+GE+P+R+GL+ TP+RVAR+YRE+FAGL+ DP +VLN  F 
Sbjct  8    VREFDQERAEAAVRELLIAVGENPEREGLLETPARVARAYREIFAGLHEDPTAVLNKTFS  67

Query  73   EDHDELVLVKEIPMYSTCEHHLVAFHGVAHVGYIPGDDGRVTGLSKIARLVDLYAKRPQV  132
            EDH ELVLV+EIP+YSTCEHHLV F GVAH+GYIPG+ G+VTGLSK+ARL D+YAKRPQV
Sbjct  68   EDHQELVLVREIPIYSTCEHHLVPFFGVAHIGYIPGESGQVTGLSKLARLADMYAKRPQV  127

Query  133  QERLTSQIADALMKKLDPRGVIVVIEAEHLCMAMRGVRKPGSVTTTSAVRGLFKTNAASR  192
            QERLTSQIADAL+ KL  + V VVIEAEHLCM MRG+RKPG+VTTTSAVRG FKT+ ASR
Sbjct  128  QERLTSQIADALVDKLGAQSVAVVIEAEHLCMGMRGIRKPGAVTTTSAVRGGFKTSMASR  187

Query  193  AEALDLI  199
            AE   LI
Sbjct  188  AEVFALI  194


>gi|331699842|ref|YP_004336081.1| GTP cyclohydrolase 1 [Pseudonocardia dioxanivorans CB1190]
 gi|326954531|gb|AEA28228.1| GTP cyclohydrolase 1 [Pseudonocardia dioxanivorans CB1190]
Length=205

 Score =  296 bits (759),  Expect = 9e-79, Method: Compositional matrix adjust.
 Identities = 143/186 (77%), Positives = 164/186 (89%), Gaps = 0/186 (0%)

Query  14   RVFDQQRAEAAVRELLYAIGEDPDRDGLVATPSRVARSYREMFAGLYTDPDSVLNTMFDE  73
            R  D+ RAEAAVRELL AIGEDPDR+GL  TP+RVAR+Y E+FAGLYTD D+VL+  FDE
Sbjct  17   RGVDRARAEAAVRELLIAIGEDPDREGLRDTPARVARAYEEIFAGLYTDADAVLDRTFDE  76

Query  74   DHDELVLVKEIPMYSTCEHHLVAFHGVAHVGYIPGDDGRVTGLSKIARLVDLYAKRPQVQ  133
             H EL+LVK+IPM+STCEHHLV FHGVAHVGYIP   GRVTGLSKIAR+V+ YA+RPQVQ
Sbjct  77   QHQELILVKDIPMFSTCEHHLVPFHGVAHVGYIPNVTGRVTGLSKIARVVENYARRPQVQ  136

Query  134  ERLTSQIADALMKKLDPRGVIVVIEAEHLCMAMRGVRKPGSVTTTSAVRGLFKTNAASRA  193
            ERLT Q+ADAL++KL+PRGVIVVI+AEHLCMAMRGVRKPGS TTTSAVRGLF T++ SRA
Sbjct  137  ERLTGQVADALVRKLEPRGVIVVIDAEHLCMAMRGVRKPGSRTTTSAVRGLFSTSSTSRA  196

Query  194  EALDLI  199
            EA+ LI
Sbjct  197  EAMSLI  202


>gi|213965109|ref|ZP_03393307.1| GTP cyclohydrolase I [Corynebacterium amycolatum SK46]
 gi|213952223|gb|EEB63607.1| GTP cyclohydrolase I [Corynebacterium amycolatum SK46]
Length=191

 Score =  296 bits (759),  Expect = 9e-79, Method: Compositional matrix adjust.
 Identities = 142/186 (77%), Positives = 162/186 (88%), Gaps = 0/186 (0%)

Query  14   RVFDQQRAEAAVRELLYAIGEDPDRDGLVATPSRVARSYREMFAGLYTDPDSVLNTMFDE  73
            R FDQ+RAEAAVRELL A+GEDPDR+GL  TP+RVAR+YRE+FAGL+ D   VL   F+E
Sbjct  3    REFDQERAEAAVRELLIAVGEDPDREGLKETPARVARAYREVFAGLFEDSSEVLAKTFNE  62

Query  74   DHDELVLVKEIPMYSTCEHHLVAFHGVAHVGYIPGDDGRVTGLSKIARLVDLYAKRPQVQ  133
            DH ELVLVK+IP+YSTCEHHLV F GVAH+GYIPG DGRVTGLSK+ARLVD YAKRPQVQ
Sbjct  63   DHQELVLVKDIPIYSTCEHHLVPFFGVAHIGYIPGKDGRVTGLSKLARLVDGYAKRPQVQ  122

Query  134  ERLTSQIADALMKKLDPRGVIVVIEAEHLCMAMRGVRKPGSVTTTSAVRGLFKTNAASRA  193
            ERLTSQ+ADAL+++LDP   IVVIEAEHLCMAMRG+RKPG+ T TSAVRG FKT+A SRA
Sbjct  123  ERLTSQVADALVERLDPASAIVVIEAEHLCMAMRGIRKPGARTVTSAVRGGFKTDARSRA  182

Query  194  EALDLI  199
            EA+ LI
Sbjct  183  EAMALI  188


>gi|134097010|ref|YP_001102671.1| GTP cyclohydrolase I [Saccharopolyspora erythraea NRRL 2338]
 gi|291006244|ref|ZP_06564217.1| GTP cyclohydrolase I [Saccharopolyspora erythraea NRRL 2338]
 gi|133909633|emb|CAL99745.1| GTP cyclohydrolase I [Saccharopolyspora erythraea NRRL 2338]
Length=213

 Score =  296 bits (758),  Expect = 1e-78, Method: Compositional matrix adjust.
 Identities = 138/171 (81%), Positives = 157/171 (92%), Gaps = 0/171 (0%)

Query  15   VFDQQRAEAAVRELLYAIGEDPDRDGLVATPSRVARSYREMFAGLYTDPDSVLNTMFDED  74
            VFDQ+RAEAA+RELL A GEDPDR+GL  TP+RVAR+YRE+FAGLYTDPD VL+  FDE 
Sbjct  26   VFDQERAEAAIRELLLAAGEDPDREGLRETPARVARAYRELFAGLYTDPDQVLDRTFDEA  85

Query  75   HDELVLVKEIPMYSTCEHHLVAFHGVAHVGYIPGDDGRVTGLSKIARLVDLYAKRPQVQE  134
            H+ELVLV+EIPMYS CEHHL+ FHGVAHVGYIP + GRVTGLSK+ARLVDLYAKRPQVQE
Sbjct  86   HEELVLVREIPMYSQCEHHLLPFHGVAHVGYIPNEKGRVTGLSKLARLVDLYAKRPQVQE  145

Query  135  RLTSQIADALMKKLDPRGVIVVIEAEHLCMAMRGVRKPGSVTTTSAVRGLF  185
            RLTSQ+ADALM++L+PRGVIVVIEAEHLCM MRG+RK GS+TTTSAVRG+F
Sbjct  146  RLTSQVADALMRRLEPRGVIVVIEAEHLCMGMRGIRKAGSMTTTSAVRGIF  196


>gi|300859208|ref|YP_003784191.1| GTP cyclohydrolase I [Corynebacterium pseudotuberculosis FRC41]
 gi|300686662|gb|ADK29584.1| GTP cyclohydrolase I [Corynebacterium pseudotuberculosis FRC41]
 gi|302206897|gb|ADL11239.1| GTP cyclohydrolase 1 [Corynebacterium pseudotuberculosis C231]
 gi|302331464|gb|ADL21658.1| GTP cyclohydrolase 1 [Corynebacterium pseudotuberculosis 1002]
 gi|308277151|gb|ADO27050.1| GTP cyclohydrolase I [Corynebacterium pseudotuberculosis I19]
 gi|341825593|gb|AEK93114.1| GTP cyclohydrolase 1 [Corynebacterium pseudotuberculosis PAT10]
Length=187

 Score =  295 bits (756),  Expect = 2e-78, Method: Compositional matrix adjust.
 Identities = 137/185 (75%), Positives = 164/185 (89%), Gaps = 0/185 (0%)

Query  15   VFDQQRAEAAVRELLYAIGEDPDRDGLVATPSRVARSYREMFAGLYTDPDSVLNTMFDED  74
            +FD+ RAEAAVRELL A+GEDP+R+GL  TP+RVA++Y E+FAGL+TDP  VLN  F ED
Sbjct  1    MFDRVRAEAAVRELLIAVGEDPEREGLKETPARVAKAYAEVFAGLHTDPTEVLNKTFSED  60

Query  75   HDELVLVKEIPMYSTCEHHLVAFHGVAHVGYIPGDDGRVTGLSKIARLVDLYAKRPQVQE  134
            H ELVLV++IP+YSTCEHHLV F G+AH+GYIPG+ G+VTGLSK+ARLVDLYAKRPQVQE
Sbjct  61   HRELVLVRDIPIYSTCEHHLVPFFGIAHIGYIPGESGKVTGLSKLARLVDLYAKRPQVQE  120

Query  135  RLTSQIADALMKKLDPRGVIVVIEAEHLCMAMRGVRKPGSVTTTSAVRGLFKTNAASRAE  194
            RLTSQ+ADAL++KL+ + VIVV+E EHLCMAMRG+RKPG+ TTTSAVRG F+TNAASRAE
Sbjct  121  RLTSQVADALVEKLEAQAVIVVLECEHLCMAMRGIRKPGATTTTSAVRGGFQTNAASRAE  180

Query  195  ALDLI  199
             L LI
Sbjct  181  VLSLI  185


>gi|258651093|ref|YP_003200249.1| GTP cyclohydrolase I [Nakamurella multipartita DSM 44233]
 gi|258554318|gb|ACV77260.1| GTP cyclohydrolase I [Nakamurella multipartita DSM 44233]
Length=220

 Score =  295 bits (754),  Expect = 3e-78, Method: Compositional matrix adjust.
 Identities = 138/184 (75%), Positives = 162/184 (89%), Gaps = 0/184 (0%)

Query  16   FDQQRAEAAVRELLYAIGEDPDRDGLVATPSRVARSYREMFAGLYTDPDSVLNTMFDEDH  75
            FDQ RAEAAVRELL A+GEDPDRDGL+ TP+RVAR+Y E FAGL+TDP  VL T FDE+H
Sbjct  34   FDQARAEAAVRELLLAVGEDPDRDGLLQTPARVARAYAEQFAGLFTDPSEVLQTSFDENH  93

Query  76   DELVLVKEIPMYSTCEHHLVAFHGVAHVGYIPGDDGRVTGLSKIARLVDLYAKRPQVQER  135
            +E++L+++I +YSTCEHHLV F G AHVGYIPG DGRVTGLSK+ARLVD YAKRPQVQER
Sbjct  94   NEMILMRDIDLYSTCEHHLVPFFGQAHVGYIPGPDGRVTGLSKLARLVDGYAKRPQVQER  153

Query  136  LTSQIADALMKKLDPRGVIVVIEAEHLCMAMRGVRKPGSVTTTSAVRGLFKTNAASRAEA  195
            LT+QIADAL+ +L P G IVVIEAEHLCMAMRG+RKPG+VTTTSAVRG+F++ A +RAEA
Sbjct  154  LTTQIADALVHRLRPAGAIVVIEAEHLCMAMRGIRKPGAVTTTSAVRGIFQSQARTRAEA  213

Query  196  LDLI  199
            + LI
Sbjct  214  MSLI  217


>gi|337291625|ref|YP_004630646.1| GTP cyclohydrolase I [Corynebacterium ulcerans BR-AD22]
 gi|334697594|gb|AEG82391.1| GTP cyclohydrolase I [Corynebacterium ulcerans 809]
 gi|334699931|gb|AEG84727.1| GTP cyclohydrolase I [Corynebacterium ulcerans BR-AD22]
Length=187

 Score =  295 bits (754),  Expect = 3e-78, Method: Compositional matrix adjust.
 Identities = 138/185 (75%), Positives = 162/185 (88%), Gaps = 0/185 (0%)

Query  15   VFDQQRAEAAVRELLYAIGEDPDRDGLVATPSRVARSYREMFAGLYTDPDSVLNTMFDED  74
            +FD+ RAEAAVRELL A+GEDP+R+GL  TP+RVA++Y E+FAGL+TDP  VLN  F ED
Sbjct  1    MFDRDRAEAAVRELLIAVGEDPEREGLQETPARVAKAYAEVFAGLHTDPTEVLNKTFSED  60

Query  75   HDELVLVKEIPMYSTCEHHLVAFHGVAHVGYIPGDDGRVTGLSKIARLVDLYAKRPQVQE  134
            H ELVLV++IP+YSTCEHHLV F G AH+GYIPG  G+VTGLSK+ARLVDLYAKRPQVQE
Sbjct  61   HRELVLVRDIPIYSTCEHHLVPFFGTAHIGYIPGQSGKVTGLSKLARLVDLYAKRPQVQE  120

Query  135  RLTSQIADALMKKLDPRGVIVVIEAEHLCMAMRGVRKPGSVTTTSAVRGLFKTNAASRAE  194
            RLTSQ+ADAL++KL+ + VIVVIE EHLCMAMRG+RKPG+ TTTSAVRG F+TNAASRAE
Sbjct  121  RLTSQVADALVEKLEAQAVIVVIECEHLCMAMRGIRKPGATTTTSAVRGGFQTNAASRAE  180

Query  195  ALDLI  199
             L LI
Sbjct  181  VLSLI  185



Lambda     K      H
   0.321    0.135    0.380 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Effective search space used: 220408776486


  Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
    Posted date:  Sep 5, 2011  4:36 AM
  Number of letters in database: 5,219,829,388
  Number of sequences in database:  15,229,318



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40