BLASTP 2.2.25+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.



Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
           15,229,318 sequences; 5,219,829,388 total letters



Query= Rv3621c

Length=413
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

gi|15843233|ref|NP_338270.1|  PPE family protein [Mycobacterium t...   791    0.0   
gi|254233119|ref|ZP_04926445.1|  PPE family protein [Mycobacteriu...   790    0.0   
gi|289571857|ref|ZP_06452084.1|  PPE family protein [Mycobacteriu...   790    0.0   
gi|289555880|ref|ZP_06445090.1|  PPE family protein [Mycobacteriu...   788    0.0   
gi|307086416|ref|ZP_07495529.1|  PPE family protein [Mycobacteriu...   781    0.0   
gi|183985089|ref|YP_001853380.1|  PPE family protein [Mycobacteri...   484    8e-135
gi|240172417|ref|ZP_04751076.1|  PPE family protein [Mycobacteriu...   433    3e-119
gi|289748134|ref|ZP_06507512.1|  PPE family protein [Mycobacteriu...   357    2e-96 
gi|296166685|ref|ZP_06849110.1|  PPE family protein [Mycobacteriu...   309    7e-82 
gi|254773196|ref|ZP_05214712.1|  PPE family protein [Mycobacteriu...   296    5e-78 
gi|183985085|ref|YP_001853376.1|  PPE family protein, PPE65 [Myco...   294    2e-77 
gi|118466000|ref|YP_879815.1|  PPE family protein [Mycobacterium ...   293    4e-77 
gi|118619369|ref|YP_907701.1|  PPE family protein [Mycobacterium ...   285    7e-75 
gi|41406540|ref|NP_959376.1|  hypothetical protein MAP0442 [Mycob...   281    2e-73 
gi|183980225|ref|YP_001848516.1|  PPE family protein, PPE51_2 [My...   251    1e-64 
gi|183981862|ref|YP_001850153.1|  PPE family protein [Mycobacteri...   235    1e-59 
gi|240172861|ref|ZP_04751520.1|  PPE family protein, PPE31 [Mycob...   216    7e-54 
gi|296167733|ref|ZP_06849950.1|  PPE family protein [Mycobacteriu...   214    2e-53 
gi|342861307|ref|ZP_08717955.1|  PPE family protein [Mycobacteriu...   209    5e-52 
gi|240171463|ref|ZP_04750122.1|  PPE family protein [Mycobacteriu...   209    6e-52 
gi|118617919|ref|YP_906251.1|  PPE family protein [Mycobacterium ...   206    4e-51 
gi|183981528|ref|YP_001849819.1|  PPE family protein, PPE51 [Myco...   206    4e-51 
gi|296170357|ref|ZP_06851948.1|  PPE family protein [Mycobacteriu...   206    5e-51 
gi|167967397|ref|ZP_02549674.1|  PPE family protein [Mycobacteriu...   206    7e-51 
gi|294996719|ref|ZP_06802410.1|  PPE family protein [Mycobacteriu...   206    8e-51 
gi|308372058|ref|ZP_07427232.2|  putative PPE family protein [Myc...   206    8e-51 
gi|183982688|ref|YP_001850979.1|  PPE family protein, PPE31_1 [My...   205    1e-50 
gi|307084423|ref|ZP_07493536.1|  putative PPE family protein [Myc...   204    2e-50 
gi|31792997|ref|NP_855490.1|  PPE family protein [Mycobacterium b...   202    6e-50 
gi|57116921|ref|YP_177844.1|  PPE family protein [Mycobacterium t...   202    7e-50 
gi|183982690|ref|YP_001850981.1|  PPE family protein, PPE31 [Myco...   202    1e-49 
gi|306782177|ref|ZP_07420514.1|  PPE family protein [Mycobacteriu...   201    1e-49 
gi|15843090|ref|NP_338127.1|  PPE family protein [Mycobacterium t...   197    2e-48 
gi|240169314|ref|ZP_04747973.1|  PPE family protein [Mycobacteriu...   196    6e-48 
gi|212595976|gb|ACJ35541.1|  PPE16 [Mycobacterium avium subsp. av...   194    2e-47 
gi|118466099|ref|YP_881935.1|  PPE family protein [Mycobacterium ...   194    3e-47 
gi|57116920|ref|YP_177653.1|  PPE family protein [Mycobacterium t...   194    3e-47 
gi|148661613|ref|YP_001283136.1|  PPE family protein [Mycobacteri...   193    4e-47 
gi|336457435|gb|EGO36444.1|  PPE-repeat containing protein [Mycob...   193    4e-47 
gi|254821012|ref|ZP_05226013.1|  PPE family protein, PPE31 [Mycob...   189    6e-46 
gi|342861296|ref|ZP_08717944.1|  PPE family protein [Mycobacteriu...   189    9e-46 
gi|340627882|ref|YP_004746334.1|  PPE family protein [Mycobacteri...   188    1e-45 
gi|289447421|ref|ZP_06437165.1|  PPE family protein [Mycobacteriu...   187    3e-45 
gi|289761957|ref|ZP_06521335.1|  predicted protein [Mycobacterium...   187    3e-45 
gi|15841277|ref|NP_336314.1|  PPE family protein [Mycobacterium t...   187    3e-45 
gi|118618458|ref|YP_906790.1|  PPE family protein [Mycobacterium ...   187    4e-45 
gi|326903411|gb|EGE50344.1|  LOW QUALITY PROTEIN: PPE family prot...   187    4e-45 
gi|296164838|ref|ZP_06847396.1|  PPE family protein [Mycobacteriu...   186    8e-45 
gi|31792996|ref|NP_855489.1|  PPE family protein [Mycobacterium b...   186    8e-45 
gi|341601736|emb|CCC64409.1|  PPE family protein [Mycobacterium b...   185    1e-44 


>gi|15843233|ref|NP_338270.1| PPE family protein [Mycobacterium tuberculosis CDC1551]
 gi|57117135|ref|YP_177998.1| PPE family protein [Mycobacterium tuberculosis H37Rv]
 gi|148663484|ref|YP_001285007.1| PPE family protein [Mycobacterium tuberculosis H37Ra]
 59 more sequence titles
 Length=413

 Score =  791 bits (2043),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 413/413 (100%), Positives = 413/413 (100%), Gaps = 0/413 (0%)

Query  1    MLDFAQLPPEVNSALMYAGPGSGPMLAAAAAWEALAAELQTTASTYDALITGLADGPWQG  60
            MLDFAQLPPEVNSALMYAGPGSGPMLAAAAAWEALAAELQTTASTYDALITGLADGPWQG
Sbjct  1    MLDFAQLPPEVNSALMYAGPGSGPMLAAAAAWEALAAELQTTASTYDALITGLADGPWQG  60

Query  61   SSAASMVAAATPQVAWLRSTAGQAEQAGSQAVAAASAYEAAFFATVPPPEIAANRALLMA  120
            SSAASMVAAATPQVAWLRSTAGQAEQAGSQAVAAASAYEAAFFATVPPPEIAANRALLMA
Sbjct  61   SSAASMVAAATPQVAWLRSTAGQAEQAGSQAVAAASAYEAAFFATVPPPEIAANRALLMA  120

Query  121  LLATNFLGQNTAAIAATEAQYAEMWAQDAAAMYGYAGASAAATQLSPFNPAAQTINPAGL  180
            LLATNFLGQNTAAIAATEAQYAEMWAQDAAAMYGYAGASAAATQLSPFNPAAQTINPAGL
Sbjct  121  LLATNFLGQNTAAIAATEAQYAEMWAQDAAAMYGYAGASAAATQLSPFNPAAQTINPAGL  180

Query  181  ASQAASVGQAVSGAANAQALTDIPKALFGLSGIFTNEPPWLTDLGKALGLTGHTWSSDGS  240
            ASQAASVGQAVSGAANAQALTDIPKALFGLSGIFTNEPPWLTDLGKALGLTGHTWSSDGS
Sbjct  181  ASQAASVGQAVSGAANAQALTDIPKALFGLSGIFTNEPPWLTDLGKALGLTGHTWSSDGS  240

Query  241  GLIVGGVLGDFVQGVTGSAELDASVAMDTFGKWVSPARLMVTQFKDYFGLAHDLPKWASE  300
            GLIVGGVLGDFVQGVTGSAELDASVAMDTFGKWVSPARLMVTQFKDYFGLAHDLPKWASE
Sbjct  241  GLIVGGVLGDFVQGVTGSAELDASVAMDTFGKWVSPARLMVTQFKDYFGLAHDLPKWASE  300

Query  301  GAKAAGEAAKALPAAVPAIPSAGLSGVAGAVGQAASVGGLKVPAVWTATTPAASPAVLAA  360
            GAKAAGEAAKALPAAVPAIPSAGLSGVAGAVGQAASVGGLKVPAVWTATTPAASPAVLAA
Sbjct  301  GAKAAGEAAKALPAAVPAIPSAGLSGVAGAVGQAASVGGLKVPAVWTATTPAASPAVLAA  360

Query  361  SNGLGAAAAAEGSTHAFGGMPLMGSGAGRAFNNFAAPRYGFKPTVIAQPPAGG  413
            SNGLGAAAAAEGSTHAFGGMPLMGSGAGRAFNNFAAPRYGFKPTVIAQPPAGG
Sbjct  361  SNGLGAAAAAEGSTHAFGGMPLMGSGAGRAFNNFAAPRYGFKPTVIAQPPAGG  413


>gi|254233119|ref|ZP_04926445.1| PPE family protein [Mycobacterium tuberculosis C]
 gi|124602912|gb|EAY61187.1| PPE family protein [Mycobacterium tuberculosis C]
Length=413

 Score =  790 bits (2040),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 412/413 (99%), Positives = 412/413 (99%), Gaps = 0/413 (0%)

Query  1    MLDFAQLPPEVNSALMYAGPGSGPMLAAAAAWEALAAELQTTASTYDALITGLADGPWQG  60
            MLDFAQLPPEVNSALMYAGPGSGPMLA AAAWEALAAELQTTASTYDALITGLADGPWQG
Sbjct  1    MLDFAQLPPEVNSALMYAGPGSGPMLAGAAAWEALAAELQTTASTYDALITGLADGPWQG  60

Query  61   SSAASMVAAATPQVAWLRSTAGQAEQAGSQAVAAASAYEAAFFATVPPPEIAANRALLMA  120
            SSAASMVAAATPQVAWLRSTAGQAEQAGSQAVAAASAYEAAFFATVPPPEIAANRALLMA
Sbjct  61   SSAASMVAAATPQVAWLRSTAGQAEQAGSQAVAAASAYEAAFFATVPPPEIAANRALLMA  120

Query  121  LLATNFLGQNTAAIAATEAQYAEMWAQDAAAMYGYAGASAAATQLSPFNPAAQTINPAGL  180
            LLATNFLGQNTAAIAATEAQYAEMWAQDAAAMYGYAGASAAATQLSPFNPAAQTINPAGL
Sbjct  121  LLATNFLGQNTAAIAATEAQYAEMWAQDAAAMYGYAGASAAATQLSPFNPAAQTINPAGL  180

Query  181  ASQAASVGQAVSGAANAQALTDIPKALFGLSGIFTNEPPWLTDLGKALGLTGHTWSSDGS  240
            ASQAASVGQAVSGAANAQALTDIPKALFGLSGIFTNEPPWLTDLGKALGLTGHTWSSDGS
Sbjct  181  ASQAASVGQAVSGAANAQALTDIPKALFGLSGIFTNEPPWLTDLGKALGLTGHTWSSDGS  240

Query  241  GLIVGGVLGDFVQGVTGSAELDASVAMDTFGKWVSPARLMVTQFKDYFGLAHDLPKWASE  300
            GLIVGGVLGDFVQGVTGSAELDASVAMDTFGKWVSPARLMVTQFKDYFGLAHDLPKWASE
Sbjct  241  GLIVGGVLGDFVQGVTGSAELDASVAMDTFGKWVSPARLMVTQFKDYFGLAHDLPKWASE  300

Query  301  GAKAAGEAAKALPAAVPAIPSAGLSGVAGAVGQAASVGGLKVPAVWTATTPAASPAVLAA  360
            GAKAAGEAAKALPAAVPAIPSAGLSGVAGAVGQAASVGGLKVPAVWTATTPAASPAVLAA
Sbjct  301  GAKAAGEAAKALPAAVPAIPSAGLSGVAGAVGQAASVGGLKVPAVWTATTPAASPAVLAA  360

Query  361  SNGLGAAAAAEGSTHAFGGMPLMGSGAGRAFNNFAAPRYGFKPTVIAQPPAGG  413
            SNGLGAAAAAEGSTHAFGGMPLMGSGAGRAFNNFAAPRYGFKPTVIAQPPAGG
Sbjct  361  SNGLGAAAAAEGSTHAFGGMPLMGSGAGRAFNNFAAPRYGFKPTVIAQPPAGG  413


>gi|289571857|ref|ZP_06452084.1| PPE family protein [Mycobacterium tuberculosis T17]
 gi|289545611|gb|EFD49259.1| PPE family protein [Mycobacterium tuberculosis T17]
Length=413

 Score =  790 bits (2039),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 412/413 (99%), Positives = 412/413 (99%), Gaps = 0/413 (0%)

Query  1    MLDFAQLPPEVNSALMYAGPGSGPMLAAAAAWEALAAELQTTASTYDALITGLADGPWQG  60
            MLDFAQLPPEVNSALMYAGPGSGPMLAAAAAWEALAAELQTTASTYDALITGLADGPWQG
Sbjct  1    MLDFAQLPPEVNSALMYAGPGSGPMLAAAAAWEALAAELQTTASTYDALITGLADGPWQG  60

Query  61   SSAASMVAAATPQVAWLRSTAGQAEQAGSQAVAAASAYEAAFFATVPPPEIAANRALLMA  120
            SSAASMVAAATPQVAWLRSTAGQAEQAGSQAVAAASAYEAAFFATVPPPEIAANRALLMA
Sbjct  61   SSAASMVAAATPQVAWLRSTAGQAEQAGSQAVAAASAYEAAFFATVPPPEIAANRALLMA  120

Query  121  LLATNFLGQNTAAIAATEAQYAEMWAQDAAAMYGYAGASAAATQLSPFNPAAQTINPAGL  180
            LLATNFLGQNTAAIAATEAQYAEMWAQDAAAMYGYAGASAAATQLSPFNPAAQTINPAGL
Sbjct  121  LLATNFLGQNTAAIAATEAQYAEMWAQDAAAMYGYAGASAAATQLSPFNPAAQTINPAGL  180

Query  181  ASQAASVGQAVSGAANAQALTDIPKALFGLSGIFTNEPPWLTDLGKALGLTGHTWSSDGS  240
            ASQAASVGQAVSGAANAQALTDIPKALFGLSGIFTNEPPWLTDLGKALGLTGHTWSSDGS
Sbjct  181  ASQAASVGQAVSGAANAQALTDIPKALFGLSGIFTNEPPWLTDLGKALGLTGHTWSSDGS  240

Query  241  GLIVGGVLGDFVQGVTGSAELDASVAMDTFGKWVSPARLMVTQFKDYFGLAHDLPKWASE  300
            GLIVGGVLGDFVQGVTGSAELDASVAMDTFGKWVSPARLMVTQFKDYFGLAHDLPKWASE
Sbjct  241  GLIVGGVLGDFVQGVTGSAELDASVAMDTFGKWVSPARLMVTQFKDYFGLAHDLPKWASE  300

Query  301  GAKAAGEAAKALPAAVPAIPSAGLSGVAGAVGQAASVGGLKVPAVWTATTPAASPAVLAA  360
            GAKAAGEAAKALPAAVPAIPSAGLSGVAGAVGQAASVGGLKVPAVWTATTPAASP VLAA
Sbjct  301  GAKAAGEAAKALPAAVPAIPSAGLSGVAGAVGQAASVGGLKVPAVWTATTPAASPTVLAA  360

Query  361  SNGLGAAAAAEGSTHAFGGMPLMGSGAGRAFNNFAAPRYGFKPTVIAQPPAGG  413
            SNGLGAAAAAEGSTHAFGGMPLMGSGAGRAFNNFAAPRYGFKPTVIAQPPAGG
Sbjct  361  SNGLGAAAAAEGSTHAFGGMPLMGSGAGRAFNNFAAPRYGFKPTVIAQPPAGG  413


>gi|289555880|ref|ZP_06445090.1| PPE family protein [Mycobacterium tuberculosis KZN 605]
 gi|289440512|gb|EFD23005.1| PPE family protein [Mycobacterium tuberculosis KZN 605]
Length=412

 Score =  788 bits (2035),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 411/412 (99%), Positives = 412/412 (100%), Gaps = 0/412 (0%)

Query  2    LDFAQLPPEVNSALMYAGPGSGPMLAAAAAWEALAAELQTTASTYDALITGLADGPWQGS  61
            +DFAQLPPEVNSALMYAGPGSGPMLAAAAAWEALAAELQTTASTYDALITGLADGPWQGS
Sbjct  1    MDFAQLPPEVNSALMYAGPGSGPMLAAAAAWEALAAELQTTASTYDALITGLADGPWQGS  60

Query  62   SAASMVAAATPQVAWLRSTAGQAEQAGSQAVAAASAYEAAFFATVPPPEIAANRALLMAL  121
            SAASMVAAATPQVAWLRSTAGQAEQAGSQAVAAASAYEAAFFATVPPPEIAANRALLMAL
Sbjct  61   SAASMVAAATPQVAWLRSTAGQAEQAGSQAVAAASAYEAAFFATVPPPEIAANRALLMAL  120

Query  122  LATNFLGQNTAAIAATEAQYAEMWAQDAAAMYGYAGASAAATQLSPFNPAAQTINPAGLA  181
            LATNFLGQNTAAIAATEAQYAEMWAQDAAAMYGYAGASAAATQLSPFNPAAQTINPAGLA
Sbjct  121  LATNFLGQNTAAIAATEAQYAEMWAQDAAAMYGYAGASAAATQLSPFNPAAQTINPAGLA  180

Query  182  SQAASVGQAVSGAANAQALTDIPKALFGLSGIFTNEPPWLTDLGKALGLTGHTWSSDGSG  241
            SQAASVGQAVSGAANAQALTDIPKALFGLSGIFTNEPPWLTDLGKALGLTGHTWSSDGSG
Sbjct  181  SQAASVGQAVSGAANAQALTDIPKALFGLSGIFTNEPPWLTDLGKALGLTGHTWSSDGSG  240

Query  242  LIVGGVLGDFVQGVTGSAELDASVAMDTFGKWVSPARLMVTQFKDYFGLAHDLPKWASEG  301
            LIVGGVLGDFVQGVTGSAELDASVAMDTFGKWVSPARLMVTQFKDYFGLAHDLPKWASEG
Sbjct  241  LIVGGVLGDFVQGVTGSAELDASVAMDTFGKWVSPARLMVTQFKDYFGLAHDLPKWASEG  300

Query  302  AKAAGEAAKALPAAVPAIPSAGLSGVAGAVGQAASVGGLKVPAVWTATTPAASPAVLAAS  361
            AKAAGEAAKALPAAVPAIPSAGLSGVAGAVGQAASVGGLKVPAVWTATTPAASPAVLAAS
Sbjct  301  AKAAGEAAKALPAAVPAIPSAGLSGVAGAVGQAASVGGLKVPAVWTATTPAASPAVLAAS  360

Query  362  NGLGAAAAAEGSTHAFGGMPLMGSGAGRAFNNFAAPRYGFKPTVIAQPPAGG  413
            NGLGAAAAAEGSTHAFGGMPLMGSGAGRAFNNFAAPRYGFKPTVIAQPPAGG
Sbjct  361  NGLGAAAAAEGSTHAFGGMPLMGSGAGRAFNNFAAPRYGFKPTVIAQPPAGG  412


>gi|307086416|ref|ZP_07495529.1| PPE family protein [Mycobacterium tuberculosis SUMu012]
 gi|308364148|gb|EFP52999.1| PPE family protein [Mycobacterium tuberculosis SUMu012]
Length=413

 Score =  781 bits (2018),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 409/413 (99%), Positives = 410/413 (99%), Gaps = 0/413 (0%)

Query  1    MLDFAQLPPEVNSALMYAGPGSGPMLAAAAAWEALAAELQTTASTYDALITGLADGPWQG  60
            MLDFAQLPPEVNSALMYAGPGSGPMLAAAAAWEALAAELQTTASTYDALITGLADGPWQG
Sbjct  1    MLDFAQLPPEVNSALMYAGPGSGPMLAAAAAWEALAAELQTTASTYDALITGLADGPWQG  60

Query  61   SSAASMVAAATPQVAWLRSTAGQAEQAGSQAVAAASAYEAAFFATVPPPEIAANRALLMA  120
            SSAASMVAAATPQVAWLRSTAGQAEQAGSQAVAAASAYEAAFFATVPPPEIAANRALLMA
Sbjct  61   SSAASMVAAATPQVAWLRSTAGQAEQAGSQAVAAASAYEAAFFATVPPPEIAANRALLMA  120

Query  121  LLATNFLGQNTAAIAATEAQYAEMWAQDAAAMYGYAGASAAATQLSPFNPAAQTINPAGL  180
            LLATNFLGQNTAAIAATEAQYAEMWAQDAAAMYGYAGASAAATQLSPFNPAAQTINPAGL
Sbjct  121  LLATNFLGQNTAAIAATEAQYAEMWAQDAAAMYGYAGASAAATQLSPFNPAAQTINPAGL  180

Query  181  ASQAASVGQAVSGAANAQALTDIPKALFGLSGIFTNEPPWLTDLGKALGLTGHTWSSDGS  240
            ASQAASVGQAVSGAANAQALTDIPKALFGLSGIFTNEPPWLTDLGKALGLTGHTWSSDGS
Sbjct  181  ASQAASVGQAVSGAANAQALTDIPKALFGLSGIFTNEPPWLTDLGKALGLTGHTWSSDGS  240

Query  241  GLIVGGVLGDFVQGVTGSAELDASVAMDTFGKWVSPARLMVTQFKDYFGLAHDLPKWASE  300
            GLIVGGVLGDFVQGVTGSAELDASVAMDTFGKWVSPARLMVTQFKDYFGLAHDLPKWASE
Sbjct  241  GLIVGGVLGDFVQGVTGSAELDASVAMDTFGKWVSPARLMVTQFKDYFGLAHDLPKWASE  300

Query  301  GAKAAGEAAKALPAAVPAIPSAGLSGVAGAVGQAASVGGLKVPAVWTATTPAASPAVLAA  360
            GAKAAGEAAKALPAAVPAIPSAGLSGVAGAVGQAASVGGL+   VWTATTPAASPAVLAA
Sbjct  301  GAKAAGEAAKALPAAVPAIPSAGLSGVAGAVGQAASVGGLEGSGVWTATTPAASPAVLAA  360

Query  361  SNGLGAAAAAEGSTHAFGGMPLMGSGAGRAFNNFAAPRYGFKPTVIAQPPAGG  413
            SNGLGAAAAAEGSTHAFGGMPLMGSGAGRAFNNFAAPRYGFKPTVIAQPPAGG
Sbjct  361  SNGLGAAAAAEGSTHAFGGMPLMGSGAGRAFNNFAAPRYGFKPTVIAQPPAGG  413


>gi|183985089|ref|YP_001853380.1| PPE family protein [Mycobacterium marinum M]
 gi|183178415|gb|ACC43525.1| PPE family protein [Mycobacterium marinum M]
Length=413

 Score =  484 bits (1247),  Expect = 8e-135, Method: Compositional matrix adjust.
 Identities = 305/415 (74%), Positives = 344/415 (83%), Gaps = 4/415 (0%)

Query  1    MLDFAQLPPEVNSALMYAGPGSGPMLAAAAAWEALAAELQTTASTYDALITGLADGPWQG  60
            MLDFAQLPPEVNSALMY+GPGSGPML AAAAW+ LAAELQ TASTYDAL+T L DGPWQG
Sbjct  1    MLDFAQLPPEVNSALMYSGPGSGPMLTAAAAWDVLAAELQATASTYDALVTELTDGPWQG  60

Query  61   SSAASMVAAATPQVAWLRSTAGQAEQAGSQAVAAASAYEAAFFATVPPPEIAANRALLMA  120
             SAA+MVAAA PQV WLR+TA  AEQAGSQAVAAA AYEAAF ATVPPP IAANRALLMA
Sbjct  61   PSAANMVAAAMPQVEWLRNTAALAEQAGSQAVAAAGAYEAAFVATVPPPVIAANRALLMA  120

Query  121  LLATNFLGQNTAAIAATEAQYAEMWAQDAAAMYGYAGASAAATQLSPFNPAAQTINPAGL  180
            L+ATNFLGQNT AIAATEAQY EMWAQDAAAMYGYAG+SAAA QL+PF+PAAQT++ AGL
Sbjct  121  LMATNFLGQNTGAIAATEAQYGEMWAQDAAAMYGYAGSSAAAAQLAPFDPAAQTVSAAGL  180

Query  181  ASQAASVGQAVSGAANAQALTDIPKALFGLSGIFTNEPPWLTDLGKALGLTGHTWSSDGS  240
            A+QAA+VGQA++GA ++QAL +IPKAL  L+GI +NEPPWLTDL  A+GLTGH W+S+G 
Sbjct  181  ANQAAAVGQALNGAVDSQALAEIPKALSQLAGI-SNEPPWLTDLTGAIGLTGHAWNSNGD  239

Query  241  GLIVGGVLGDFVQGVTGSAELDASVAMDTFGKWVSPARLMVTQFKDYFGLAHDLPKWASE  300
            G+IVGG LGD VQGVTGSAE+DA V MDTF KWVSPARL VTQFKDY GLAHDLPK+A E
Sbjct  240  GIIVGGALGDIVQGVTGSAEVDAGVFMDTFSKWVSPARLAVTQFKDYVGLAHDLPKFAQE  299

Query  301  GAKAAGEAAKALPAAVPAIPSAGLSGVAGAVGQAASVGGLKVPAVWTATTPAASPAVLAA  360
            GAKAA EAAK LPA +P++P  GL G+ GAVG+AASV GL VP  W  +  AA+   +  
Sbjct  300  GAKAAAEAAKELPAVLPSLPGVGLGGITGAVGKAASVTGLSVPTSWMNSVGAAANPAIVT  359

Query  361  SNGLGAAAAAEGSTHAFGGMPLM-GSGAGRAF-NNFAAPRYGFKPTVIAQPPAGG  413
             N LGAAAA   +  A GG+PLM  SG GR    +FAAPRYGFKPT++  PPAGG
Sbjct  360  VNSLGAAAAEP-AQAAVGGVPLMPASGVGRGMAAHFAAPRYGFKPTMVVHPPAGG  413


>gi|240172417|ref|ZP_04751076.1| PPE family protein [Mycobacterium kansasii ATCC 12478]
Length=412

 Score =  433 bits (1113),  Expect = 3e-119, Method: Compositional matrix adjust.
 Identities = 298/415 (72%), Positives = 347/415 (84%), Gaps = 6/415 (1%)

Query  2    LDFAQLPPEVNSALMYAGPGSGPMLAAAAAWEALAAELQTTASTYDALITGLADGPWQGS  61
            +DFAQLPPE+NSALMY+GPGSGPMLAAAAAW+ALAAELQ+TAS+YDAL+T L DGPWQG 
Sbjct  1    MDFAQLPPEINSALMYSGPGSGPMLAAAAAWDALAAELQSTASSYDALVTALTDGPWQGP  60

Query  62   SAASMVAAATPQVAWLRSTAGQAEQAGSQAVAAASAYEAAFFATVPPPEIAANRALLMAL  121
            SAASMVAAA PQVAWLRSTA QAEQAG QAVAAA+AYEAAF ATVPP E+AANRAL+MAL
Sbjct  61   SAASMVAAAMPQVAWLRSTAAQAEQAGGQAVAAATAYEAAFMATVPPAEVAANRALMMAL  120

Query  122  LATNFLGQNTAAIAATEAQYAEMWAQDAAAMYGYAGASAAATQLSPFNPAAQTINPAGLA  181
            LATNFLGQNTAAIAATEAQYAEMWAQDAAAMYGYAGASA AT L+PF+PA  T+N AG+ 
Sbjct  121  LATNFLGQNTAAIAATEAQYAEMWAQDAAAMYGYAGASAQATTLTPFSPALPTVNLAGVV  180

Query  182  SQAASVGQAVSGAANAQALTDIPKALFGLSGIFTNEPPWLTDLGKALGLTGHTWSSDGSG  241
            +QA +V QAVS +A AQ +T I  +L  ++G+ TNE PWL++   ALGL GHTW+S+G G
Sbjct  181  AQANAVAQAVSTSAPAQGMTQITNSLLQMAGL-TNEAPWLSNPLAALGLVGHTWNSNGDG  239

Query  242  LIVGGVLGDFVQGVTGSAELDASVAMDTFGKWVSPARLMVTQFKDYFGLAHDLPKWASEG  301
            ++V G+ GD V+G+TGSA +D S+ MD F +WVSPARL+VTQ KDYFGLAHDLPKWASEG
Sbjct  240  IVVAGLFGDVVEGLTGSATVDGSLPMDVFNRWVSPARLVVTQMKDYFGLAHDLPKWASEG  299

Query  302  AKAAGEAAKALPAAVP-AIPSAGLSGVAGAVGQAASVGGLKVPAVWTATTPAASPAVLAA  360
            A++A +AAK    A+P A+PSAGL G+AGAVG+AASVGGL VPA W  T   A+P ++  
Sbjct  300  AESAAKAAKGAIEALPAALPSAGLGGIAGAVGKAASVGGLSVPASWANTVGPANP-IVTI  358

Query  361  SNGLGAAAAAEGSTHAFGGMPLM-GSGAGRAF-NNFAAPRYGFKPTVIAQPPAGG  413
            SN LGAAAAAE +  AFGGMP+M GSG GR    +FAAPRYGFKPTV+ QPPAGG
Sbjct  359  SN-LGAAAAAEPAASAFGGMPVMPGSGVGRGMAAHFAAPRYGFKPTVVPQPPAGG  412


>gi|289748134|ref|ZP_06507512.1| PPE family protein [Mycobacterium tuberculosis T92]
 gi|289688721|gb|EFD56150.1| PPE family protein [Mycobacterium tuberculosis T92]
Length=184

 Score =  357 bits (917),  Expect = 2e-96, Method: Compositional matrix adjust.
 Identities = 183/184 (99%), Positives = 184/184 (100%), Gaps = 0/184 (0%)

Query  230  LTGHTWSSDGSGLIVGGVLGDFVQGVTGSAELDASVAMDTFGKWVSPARLMVTQFKDYFG  289
            +TGHTWSSDGSGLIVGGVLGDFVQGVTGSAELDASVAMDTFGKWVSPARLMVTQFKDYFG
Sbjct  1    MTGHTWSSDGSGLIVGGVLGDFVQGVTGSAELDASVAMDTFGKWVSPARLMVTQFKDYFG  60

Query  290  LAHDLPKWASEGAKAAGEAAKALPAAVPAIPSAGLSGVAGAVGQAASVGGLKVPAVWTAT  349
            LAHDLPKWASEGAKAAGEAAKALPAAVPAIPSAGLSGVAGAVGQAASVGGLKVPAVWTAT
Sbjct  61   LAHDLPKWASEGAKAAGEAAKALPAAVPAIPSAGLSGVAGAVGQAASVGGLKVPAVWTAT  120

Query  350  TPAASPAVLAASNGLGAAAAAEGSTHAFGGMPLMGSGAGRAFNNFAAPRYGFKPTVIAQP  409
            TPAASPAVLAASNGLGAAAAAEGSTHAFGGMPLMGSGAGRAFNNFAAPRYGFKPTVIAQP
Sbjct  121  TPAASPAVLAASNGLGAAAAAEGSTHAFGGMPLMGSGAGRAFNNFAAPRYGFKPTVIAQP  180

Query  410  PAGG  413
            PAGG
Sbjct  181  PAGG  184


>gi|296166685|ref|ZP_06849110.1| PPE family protein [Mycobacterium parascrofulaceum ATCC BAA-614]
 gi|295897950|gb|EFG77531.1| PPE family protein [Mycobacterium parascrofulaceum ATCC BAA-614]
Length=405

 Score =  309 bits (791),  Expect = 7e-82, Method: Compositional matrix adjust.
 Identities = 244/422 (58%), Positives = 285/422 (68%), Gaps = 26/422 (6%)

Query  1    MLDFAQLPPEVNSALMYAGPGSGPMLAAAAAWEALAAELQTTASTYDALITGLADGPWQG  60
            MLDF  LPPE+NSALMY+GPGSGPMLAAAA+WEALAA+L  TAS Y +++TGL DGPW G
Sbjct  1    MLDFGLLPPEINSALMYSGPGSGPMLAAAASWEALAADLANTASGYLSVVTGLTDGPWLG  60

Query  61   SSAASMVAAATPQVAWLRSTAGQAEQAGSQAVAAASAYEAAFFATVPPPEIAANRALLMA  120
             +A SM  AATPQ+AWL  TAGQAE A +QA AAASAYEAAF ATVPPP IAANR LLM 
Sbjct  61   GAALSMAGAATPQIAWLNGTAGQAEHAAAQAAAAASAYEAAFAATVPPPVIAANRVLLME  120

Query  121  LLATNFLGQNTAAIAATEAQYAEMWAQDAAAMYGYAGASAAATQLSPFNPAAQTINPAGL  180
            LLATNFLGQNT AIAATE QY EMWAQDAAAMYGYA  SAAA  L PF+PAA   NPAG+
Sbjct  121  LLATNFLGQNTPAIAATETQYLEMWAQDAAAMYGYAAESAAAATLPPFDPAAPATNPAGV  180

Query  181  ASQAASVGQAVSGAA-----NAQALTD-IPKALFGLSGIFTNEPPWLTDLGKALGLTGHT  234
            A+Q  +V QAV+ +A        ALTD +P  L GL+G      P+    G    + G T
Sbjct  181  AAQEVAVAQAVASSAAAETQELSALTDAMPGTLAGLAGPQAAANPF----GNL--VNGGT  234

Query  235  WSSDGSGLIVGGVLGDFVQGVTGSAELDASVAMDTFGKWVSPARLMVTQFKDYFGLAHDL  294
               DG G       G  ++ +TGS+ L     +D F +WV P+RL +T F+D  GL+H +
Sbjct  235  LELDGMG-------GALLESLTGSSTLHPGTPIDMFKEWVGPSRLFITIFRDLEGLSHSM  287

Query  295  --PKWASEGAKAAGEAAKALPAAVPAIPSAGLSGVAGAVGQAASVGGLKVPAVWTATTPA  352
                 A   A AA  A  ALPA   A+ SAGLSG AGAVG+A +VG L VP  W A    
Sbjct  288  APKAAAQAVAGAAKAAGSALPA---ALSSAGLSGPAGAVGKAVTVGALSVPQAW-ANVAP  343

Query  353  ASPAVLAASNGLGAAAAAEGSTHAFGGMPLMGSGAGRAFN-NFAAPRYGFKPTVIAQPPA  411
            A+    A  NGL A+AA E +THA GG+P++GSG GR  + NFAAPRYGFKP VI  PPA
Sbjct  344  AATPAAATLNGLAASAAVEPATHAVGGVPMVGSGLGRGMSANFAAPRYGFKPAVIPHPPA  403

Query  412  GG  413
            GG
Sbjct  404  GG  405


>gi|254773196|ref|ZP_05214712.1| PPE family protein [Mycobacterium avium subsp. avium ATCC 25291]
 gi|212595880|gb|ACJ35530.1| PPE3 [Mycobacterium avium subsp. avium]
Length=421

 Score =  296 bits (758),  Expect = 5e-78, Method: Compositional matrix adjust.
 Identities = 234/422 (56%), Positives = 284/422 (68%), Gaps = 17/422 (4%)

Query  2    LDFAQLPPEVNSALMYAGPGSGPMLAAAAAWEALAAELQTTASTYDALITGLADGPWQGS  61
            LDFAQLPPE+NS LMY+GPG+GP+LAAAAAW  LAAEL++ A+++ + ITG+ D  WQG 
Sbjct  7    LDFAQLPPEINSGLMYSGPGAGPLLAAAAAWNGLAAELRSAAASFGSAITGVGDAGWQGP  66

Query  62   SAASMVAAATPQVAWLRSTAGQAEQAGSQAVAAASAYEAAFFATVPPPEIAANRALLMAL  121
            +A+SM+AAA PQ+AWL  TAG+AE A  QA+AA SAYE AF  TVPPP IAANRALL+ L
Sbjct  67   AASSMLAAAAPQLAWLSGTAGRAELAAGQALAAVSAYETAFAETVPPPVIAANRALLLQL  126

Query  122  LATNFLGQNTAAIAATEAQYAEMWAQDAAAMYGYAGASAAATQLSPFNPAAQTINPAGLA  181
            LATNFLGQNT AIA  EAQY EMWAQDAAAMYGYA ASAAA+ L PF PA    +PAGLA
Sbjct  127  LATNFLGQNTPAIADVEAQYGEMWAQDAAAMYGYALASAAASTLPPFEPAKPATDPAGLA  186

Query  182  SQAASVGQAVSGAA--NAQALTDIPKALFGLSGIFTNEPPWLTDLGKALGLTGHTWSSDG  239
             QAA+  QA    A   AQ L   P+++  L+    N PP   + G +LG  G + + +G
Sbjct  187  RQAAATAQAAGTGAGDRAQGLGAAPQSMSTLAAGTNNPPP--ANPGFSLG--GISLNPEG  242

Query  240  SGLIVGGVLGDFVQGVTGSAELDASVAMDTFGKWVSPARLMVTQFKDYFGLAHDL---PK  296
             GL++GG LGD ++G+TGS  LDAS   D F + +SP RL  T FKD  G+A  +    K
Sbjct  243  DGLVIGGPLGDLLEGLTGSQTLDASTPFDAFIRLISPTRLFTTSFKDIQGIAQGMMPAAK  302

Query  297  WASEGAKAAGEAAKALPAAVP---AIPSAGLSGVAGAVGQAASVGGLKVPAVWTATTPAA  353
             A EG   A EA   LPAAVP         L  + G+VG+AAS+GGL VPA W +  P  
Sbjct  303  SAGEGVAKAAEA--VLPAAVPGAGLGSLGSLGSIGGSVGKAASIGGLSVPASWASAAP-T  359

Query  354  SPAVLAASNGLGAAAAAEGSTHAFGGMPLM--GSGAGRAFNNFAAPRYGFKPTVIAQPPA  411
             P+V  A NG   A AAE +  A GG+P+M  G+    A  +F  PRYGFKPTVIAQPPA
Sbjct  360  PPSVAVALNGATTAGAAEHAASAVGGVPMMPAGAAGRGAGAHFVVPRYGFKPTVIAQPPA  419

Query  412  GG  413
            GG
Sbjct  420  GG  421


>gi|183985085|ref|YP_001853376.1| PPE family protein, PPE65 [Mycobacterium marinum M]
 gi|183178411|gb|ACC43521.1| PPE family protein, PPE65 [Mycobacterium marinum M]
Length=418

 Score =  294 bits (752),  Expect = 2e-77, Method: Compositional matrix adjust.
 Identities = 219/421 (53%), Positives = 276/421 (66%), Gaps = 11/421 (2%)

Query  1    MLDFAQLPPEVNSALMYAGPGSGPMLAAAAAWEALAAELQTTASTYDALITGLADGPWQG  60
            MLDFA LPPEVNS LMY+GPGSG MLAAAAAW+AL AELQ TA++Y +L++GL  GPW G
Sbjct  1    MLDFALLPPEVNSTLMYSGPGSGSMLAAAAAWQALGAELQCTANSYRSLLSGLVSGPWSG  60

Query  61   SSAASMVAAATPQVAWLRSTAGQAEQAGSQAVAAASAYEAAFFATVPPPEIAANRALLMA  120
             +AA+M AAA P +AWL +TA QAEQ G QA AAASAYEAAF   VPP  +AANRA+L  
Sbjct  61   PAAAAMSAAAAPHLAWLSATAAQAEQVGRQAAAAASAYEAAFAGMVPPAVVAANRAMLAT  120

Query  121  LLATNFLGQNTAAIAATEAQYAEMWAQDAAAMYGYAGASAAATQLSPFNPAAQTINPAGL  180
            L+ATN  GQNT AIA  EA+YAEMWAQDA AMY YA  +AAA  L+ F P        G 
Sbjct  121  LVATNLFGQNTPAIAVVEAEYAEMWAQDANAMYQYAATAAAAADLTSFVPPRPATTANGP  180

Query  181  ASQAASVGQAVSG--AANAQAL----TDIPKALFGLSGIFTNEPPWLTDLGKALGLTGHT  234
            A+QAA+VG+A     A +AQ+L      +P AL GLS       P L  + +ALGL G  
Sbjct  181  AAQAAAVGRATGDLLAGDAQSLQQLVEQLPNALRGLSEAALV--PSLERILRALGLIGWK  238

Query  235  WSSDGSGLIVGGVLGDFVQGVTGSAELDASVAMDTFGKWVSPARLMVTQFKDYFGLAHDL  294
            W+ +G G+++ G LG  + G+TGS+ LDAS   +T+ + VSP RL  T  KD  GL+H L
Sbjct  239  WTPNGDGIVLSGALGALIAGLTGSSTLDASTLSNTYIRLVSPFRLTTTALKDIDGLSHSL  298

Query  295  PKWASEGAKAAGEAAKALPAAVPAIPSAGLSGVAGAVGQAASVGGLKVPAVWTATTPA-A  353
               A+   + A +A +ALP A+P +P +G+S   G +G+AA +GGL VP  W ++ P   
Sbjct  299  FPAAAHAGQEAAKAVEALPQALPKLPLSGVSSGLGGIGRAAQIGGLSVPNAWASSMPGLG  358

Query  354  SPAVLAASNGLGAAAAAEGSTHAFGGMPLMGSGAGRAFNNFAA-PRYGFKPTVIAQPPAG  412
              A +  S+   AAAAA+ S H FGG+P  G+ A R F   AA PRYGF P V+ +PPA 
Sbjct  359  RVATVPLSSVAAAAAAADPSQHVFGGLPAHGTPA-RGFAASAAPPRYGFHPRVMTRPPAA  417

Query  413  G  413
            G
Sbjct  418  G  418


>gi|118466000|ref|YP_879815.1| PPE family protein [Mycobacterium avium 104]
 gi|118167287|gb|ABK68184.1| PPE family protein [Mycobacterium avium 104]
Length=421

 Score =  293 bits (750),  Expect = 4e-77, Method: Compositional matrix adjust.
 Identities = 235/422 (56%), Positives = 287/422 (69%), Gaps = 17/422 (4%)

Query  2    LDFAQLPPEVNSALMYAGPGSGPMLAAAAAWEALAAELQTTASTYDALITGLADGPWQGS  61
            LDFAQLPPE+NS LMY+GPG+GP+LAAAAAW  LAAEL++ A+++ ++ITG+ D  WQG 
Sbjct  7    LDFAQLPPEINSGLMYSGPGAGPLLAAAAAWNGLAAELRSAAASFGSVITGVGDAGWQGP  66

Query  62   SAASMVAAATPQVAWLRSTAGQAEQAGSQAVAAASAYEAAFFATVPPPEIAANRALLMAL  121
            +A+SM+AAA PQ+AWL  TAG+AE A  QA+AA SAYE AF  TVPPP IAANRALL+ L
Sbjct  67   AASSMMAAAAPQLAWLSGTAGRAELAAGQALAAVSAYETAFAETVPPPVIAANRALLLQL  126

Query  122  LATNFLGQNTAAIAATEAQYAEMWAQDAAAMYGYAGASAAATQLSPFNPAAQTINPAGLA  181
            LATNFLGQNT AIA  EAQY EMWAQDAAAMYGYA ASAAA+ L PF PA    +PAGLA
Sbjct  127  LATNFLGQNTPAIADVEAQYGEMWAQDAAAMYGYALASAAASTLPPFEPAKPATDPAGLA  186

Query  182  SQAASVGQAVSGAA--NAQALTDIPKALFGLSGIFTNEPPWLTDLGKALGLTGHTWSSDG  239
             QAA+  QA    A  +AQ L   P+++  L+   TN PP   + G +LG  G + + +G
Sbjct  187  RQAAATAQAAGTGAGDSAQGLGAAPQSMSTLAA-GTNNPP-AANPGFSLG--GISLNPEG  242

Query  240  SGLIVGGVLGDFVQGVTGSAELDASVAMDTFGKWVSPARLMVTQFKDYFGLAHDL---PK  296
             GL++GG LGD ++G+TGS  LDAS   D F + +SP RL  T FKD  G+A  +    K
Sbjct  243  DGLVIGGPLGDLLEGLTGSQTLDASTPFDAFIRLISPTRLFTTSFKDIQGIAQGMMPAAK  302

Query  297  WASEGAKAAGEAAKALPAAVP---AIPSAGLSGVAGAVGQAASVGGLKVPAVWTATTPAA  353
             A EG   A EA   LPAAVP         L  + G+VG+AAS+GGL VPA W +  P  
Sbjct  303  SAGEGVAKAAEA--VLPAAVPGAGLGSLGSLGSIGGSVGKAASIGGLSVPASWASAAP-T  359

Query  354  SPAVLAASNGLGAAAAAEGSTHAFGGMPLM--GSGAGRAFNNFAAPRYGFKPTVIAQPPA  411
             P+V  A NG   A AAE +  A GG+P+M  G+    A  +F  PRYGFKPTVIAQPPA
Sbjct  360  PPSVAVALNGATTAGAAEHAASAVGGVPMMPAGAAGRGAGAHFVVPRYGFKPTVIAQPPA  419

Query  412  GG  413
            GG
Sbjct  420  GG  421


>gi|118619369|ref|YP_907701.1| PPE family protein [Mycobacterium ulcerans Agy99]
 gi|118571479|gb|ABL06230.1| PPE family protein [Mycobacterium ulcerans Agy99]
Length=418

 Score =  285 bits (730),  Expect = 7e-75, Method: Compositional matrix adjust.
 Identities = 216/421 (52%), Positives = 273/421 (65%), Gaps = 11/421 (2%)

Query  1    MLDFAQLPPEVNSALMYAGPGSGPMLAAAAAWEALAAELQTTASTYDALITGLADGPWQG  60
            MLDFA LPP+VNS LMY+GPGSG MLAAAAAW+AL AELQ TA +Y +L++GL  GPW G
Sbjct  1    MLDFALLPPKVNSTLMYSGPGSGSMLAAAAAWQALGAELQCTADSYRSLLSGLVSGPWSG  60

Query  61   SSAASMVAAATPQVAWLRSTAGQAEQAGSQAVAAASAYEAAFFATVPPPEIAANRALLMA  120
             +AA+M AAA P +AWL +TA QAEQ G QA AAASAYEAAF   VPP  +AANRA+L  
Sbjct  61   PAAAAMSAAAAPHLAWLSATAAQAEQVGRQAAAAASAYEAAFAGMVPPAVVAANRAMLAT  120

Query  121  LLATNFLGQNTAAIAATEAQYAEMWAQDAAAMYGYAGASAAATQLSPFNPAAQTINPAGL  180
            L+ATN  GQNT AIA  EA+YA+MWAQDA AMY YA  +AAA  L+ F P        G 
Sbjct  121  LVATNLFGQNTPAIAVVEAEYAKMWAQDANAMYQYAATAAAAADLTSFVPPRPATTANGP  180

Query  181  ASQAASVGQAVSG--AANAQAL----TDIPKALFGLSGIFTNEPPWLTDLGKALGLTGHT  234
            A+QAA+VG+A     A +AQ+L      +P AL GLS       P L  + +ALGL G  
Sbjct  181  AAQAAAVGRATGDLLAGDAQSLQQLVEQLPNALRGLSEAALV--PSLERILRALGLIGWK  238

Query  235  WSSDGSGLIVGGVLGDFVQGVTGSAELDASVAMDTFGKWVSPARLMVTQFKDYFGLAHDL  294
            W+ +G G+++ G LG  + G TGS+ LDAS   +T+ + VSP RL  T  KD  GL+H L
Sbjct  239  WTPNGDGIVLSGALGALIAGPTGSSTLDASTLSNTYIRLVSPFRLTTTALKDIDGLSHSL  298

Query  295  PKWASEGAKAAGEAAKALPAAVPAIPSAGLSGVAGAVGQAASVGGLKVPAVWTATTPA-A  353
               A+   + A +A +ALP A+P +  +G+S   G +G+AA +GGL VP  W ++ P   
Sbjct  299  FPAAAHAGQEAAKAVEALPQALPKLSLSGVSSGLGGIGRAAQIGGLSVPNAWASSMPGLG  358

Query  354  SPAVLAASNGLGAAAAAEGSTHAFGGMPLMGSGAGRAFNNFAA-PRYGFKPTVIAQPPAG  412
              A +  S+   AAAAA+ S H FGG+P  G+ A R F   AA PRYGF P V+ +PPA 
Sbjct  359  RVATVPLSSVAAAAAAADPSQHVFGGLPAHGTPA-RGFAASAAPPRYGFHPRVMTRPPAA  417

Query  413  G  413
            G
Sbjct  418  G  418


>gi|41406540|ref|NP_959376.1| hypothetical protein MAP0442 [Mycobacterium avium subsp. paratuberculosis 
K-10]
 gi|41394889|gb|AAS02759.1| hypothetical protein MAP_0442 [Mycobacterium avium subsp. paratuberculosis 
K-10]
Length=424

 Score =  281 bits (718),  Expect = 2e-73, Method: Compositional matrix adjust.
 Identities = 203/383 (54%), Positives = 250/383 (66%), Gaps = 14/383 (3%)

Query  38   ELQTTASTYDALITGLADGPWQGSSAASMVAAATPQVAWLRSTAGQAEQAGSQAVAAASA  97
            EL++ A+++ ++ITG+ D  WQG +A+SM+AAA PQ+AWL  TAG+AE A  QA+AA SA
Sbjct  49   ELRSAAASFGSVITGVGDAGWQGPAASSMMAAAAPQLAWLSGTAGRAELAAGQALAAVSA  108

Query  98   YEAAFFATVPPPEIAANRALLMALLATNFLGQNTAAIAATEAQYAEMWAQDAAAMYGYAG  157
            YE AF  TVPPP IAANRALL+ LLATNFLGQNT AIA  EAQY EMWAQD AAMYGYA 
Sbjct  109  YETAFAETVPPPVIAANRALLLQLLATNFLGQNTPAIADVEAQYGEMWAQDTAAMYGYAL  168

Query  158  ASAAATQLSPFNPAAQTINPAGLASQAASVGQAVSGAA--NAQALTDIPKALFGLSGIFT  215
            ASAAA+ L PF PA    +PAGLA QAA+  QA    A  +AQ L   P+ +  L+    
Sbjct  169  ASAAASTLPPFEPAKPATDPAGLARQAAATAQAAGTGAGDSAQGLGAAPQPMSTLAAGTN  228

Query  216  NEPPWLTDLGKALGLTGHTWSSDGSGLIVGGVLGDFVQGVTGSAELDASVAMDTFGKWVS  275
            N PP   + G +LG  G + + +G GL++GG LGD ++G+TGS  LDAS   D F + +S
Sbjct  229  NPPP--ANPGFSLG--GISLNPEGDGLVIGGPLGDLLEGLTGSQTLDASTPFDAFIRLIS  284

Query  276  PARLMVTQFKDYFGLAHDL---PKWASEGAKAAGEAAKALPAAVPAIPSAGLSGVAGAVG  332
            P RL  T FKD  G+A  +    K A EG   A EA   LPAAVP      L  + G+VG
Sbjct  285  PTRLFTTSFKDIQGIAQGMMPAAKSAGEGVAKAAEA--VLPAAVPGAGLGSLGSIGGSVG  342

Query  333  QAASVGGLKVPAVWTATTPAASPAVLAASNGLGAAAAAEGSTHAFGGMPLM--GSGAGRA  390
            +AAS+GGL VPA W +  P   P+V  A NG     AAE +  A GG+P+M  G+    A
Sbjct  343  KAASIGGLSVPASWASAAP-TPPSVAVALNGATTTGAAEHAASAVGGVPMMPAGAAGRGA  401

Query  391  FNNFAAPRYGFKPTVIAQPPAGG  413
              +F  PRYGFKPTVIAQPPAGG
Sbjct  402  GAHFVVPRYGFKPTVIAQPPAGG  424


>gi|183980225|ref|YP_001848516.1| PPE family protein, PPE51_2 [Mycobacterium marinum M]
 gi|183173551|gb|ACC38661.1| PPE family protein, PPE51_2 [Mycobacterium marinum M]
Length=381

 Score =  251 bits (642),  Expect = 1e-64, Method: Compositional matrix adjust.
 Identities = 179/416 (44%), Positives = 231/416 (56%), Gaps = 39/416 (9%)

Query  2    LDFAQLPPEVNSALMYAGPGSGPMLAAAAAWEALAAELQTTASTYDALITGLADGPWQGS  61
            +DFA LPPEVNS LMY GPG+G +LAAA +W+ LA EL TTA TY+++++GL    W G 
Sbjct  1    MDFAMLPPEVNSGLMYTGPGAGSLLAAANSWDELAIELGTTAQTYESVLSGLTSMYWAGP  60

Query  62   SAASMVAAATPQVAWLRSTAGQAEQAGSQAVAAASAYEAAFFATVPPPEIAANRALLMAL  121
            ++ SM A A P V WL STA Q +Q  +Q  AAA A+E A+  TVPPP I ANR  LM+L
Sbjct  61   ASESMAAKAAPYVWWLHSTAEQTQQTATQCRAAAMAFEQAYAMTVPPPVILANRMQLMSL  120

Query  122  LATNFLGQNTAAIAATEAQYAEMWAQDAAAMYGYAGASAAATQLSPFNPAAQTINPAGLA  181
            +ATNF GQNTAAIAA EAQYAEMW QDAAAMYGYA ++A A QL PF+   QT NPAGL+
Sbjct  121  VATNFFGQNTAAIAALEAQYAEMWEQDAAAMYGYATSAAMAAQLVPFSSPQQTTNPAGLS  180

Query  182  SQAASVGQAVSGAANAQALTD----IPKALFGLSGIFTNEPPWLTDLGKALGLTGHTWSS  237
            +Q+A+V QA + AA A  L+D    + K L  L+G F N  P   D     G+       
Sbjct  181  AQSAAVNQADATAAAANPLSDLIALVQKGLAALAGAFPNLLP--DDFSILDGIF------  232

Query  238  DGSGLIVGGVLGDFVQGVTGSAELDASVAMDTFGKWVSPARLMVTQFKDYFGLAHDLPKW  297
              +G    GV  D    + G    ++++ M                     G A + P  
Sbjct  233  --AGYATVGVSQDCESIIAGIIGAESNLGM--------------------LGAASENPAE  270

Query  298  ASEGAKAAGEAAKALPAAVPAIPSAGLSGVAGAVGQAASVGGLKVPAVWTATTPAASPAV  357
             + G    G    + P+   A+  +G   V  +VG+A S+G L VPA W A  PA     
Sbjct  271  LAPGDIGIGSVLSSAPSVGGAV--SGPGAVLVSVGRAGSIGQLSVPASWAA--PATRQVA  326

Query  358  LAASNGLGAAAAAEGSTHAFGGMPLMGSGAGRAFNNFAAPRYGFKPTVIAQPPAGG  413
              +S GL      E + H   GMP M  G+    ++   PRYG + TV+A PPA G
Sbjct  327  ALSSAGLTTIPGTEEAAHGIPGMPGMPVGSSSRASSV-VPRYGVRLTVMAHPPAAG  381


>gi|183981862|ref|YP_001850153.1| PPE family protein [Mycobacterium marinum M]
 gi|183175188|gb|ACC40298.1| PPE family protein [Mycobacterium marinum M]
Length=418

 Score =  235 bits (600),  Expect = 1e-59, Method: Compositional matrix adjust.
 Identities = 196/429 (46%), Positives = 243/429 (57%), Gaps = 28/429 (6%)

Query  2    LDFAQLPPEVNSALMYAGPGSGPMLAAAAAWEALAAELQTTASTYDALITGLADGPWQGS  61
            +D+A LPPEVNSA MY GPGSGPMLAAA AW+ L+ EL + A+ Y + +  +  GPW+G 
Sbjct  1    MDYAALPPEVNSARMYTGPGSGPMLAAALAWDGLSTELSSAAADYSSALAAMTSGPWRGP  60

Query  62   SAASMVAAATPQVAWLRSTAGQAEQAGSQAVAAASAYEAAFFATVPPPEIAANRALLMAL  121
            ++ SM +AA P +AW+  TA QA QA  QA AAA AYEAAF  TVPPP IAANRALL +L
Sbjct  61   ASTSMASAAAPYIAWMAGTATQALQASLQAKAAAGAYEAAFAVTVPPPMIAANRALLASL  120

Query  122  LATNFLGQNTAAIAATEAQYAEMWAQDAAAMYGYAGASAAATQLSPF-NPAAQTINPAGL  180
            +ATN LGQNT AIAA EA Y EMWAQDAAAMYGYA   A AT+L+PF +P   T   AGL
Sbjct  121  VATNLLGQNTPAIAAAEATYGEMWAQDAAAMYGYAACCATATRLTPFADPPPTTSPEAGL  180

Query  181  ASQAASVGQAVSGAANAQALTDIPKALFGL-----SGIFTNE--------PPWLTDLGKA  227
             +QAA+   A S A+ +Q ++ +P AL GL     SG+   E         P L  +   
Sbjct  181  IAQAATTSSAQSQASLSQVMSMVPTALQGLASPSASGVTITEVAGALGLGAPQLDGIQSW  240

Query  228  LGLTGHTWSSDGSGLIVGGVLGDFVQGVTGSAELDASVAMDT--FGK-WVSPARLMVTQF  284
            LGL G   ++  SGL+       F  G  GS    A  A+ T   G  + +P     T  
Sbjct  241  LGLQGIDLTTP-SGLLA------FFNGTDGSPLGTAVNAITTNAIGSGFYTPGNFFGT-M  292

Query  285  KDYFGLAHDLPKWASEGAKAAGEAAKALPAAVPAIPSAGLSGVAGAVGQAASVGGLKVPA  344
             D+FGL+      A+E A  A  +     A          + V+  VG AAS+G L VP 
Sbjct  293  CDFFGLSSFSAMDAAEDAAIAASSGLGGAAPGLGGFGGLGTAVSAGVGNAASIGSLSVPP  352

Query  345  VWTATTPAASPAVLAASNGLGAAAAAEGSTHAFGGMPLMGSGAGRAFNNFAAPRYGFKPT  404
             W AT+P  +      S   GA   A G     GG+PL G G GR F+    PRYGFKPT
Sbjct  353  TWAATSPVGAAVATLPSVAAGAPLTAHGPASMLGGLPLSGFG-GRGFSE--VPRYGFKPT  409

Query  405  VIAQPPAGG  413
            V+  PPA G
Sbjct  410  VVMHPPAAG  418


>gi|240172861|ref|ZP_04751520.1| PPE family protein, PPE31 [Mycobacterium kansasii ATCC 12478]
Length=401

 Score =  216 bits (549),  Expect = 7e-54, Method: Compositional matrix adjust.
 Identities = 148/240 (62%), Positives = 175/240 (73%), Gaps = 8/240 (3%)

Query  2    LDFAQLPPEVNSALMYAGPGSGPMLAAAAAWEALAAELQTTASTYDALITGLADGPWQGS  61
            LDFA LPPE+NSA MY+GPGSGPMLAAA+AW++LAAEL+ TA +Y +++  L    W G 
Sbjct  5    LDFAMLPPEINSARMYSGPGSGPMLAAASAWKSLAAELRATALSYHSVLAALTGEEWYGP  64

Query  62   SAASMVAAATPQVAWLRSTAGQAEQAGSQAVAAASAYEAAFFATVPPPEIAANRALLMAL  121
            ++ASM AAA P VAWL +TA QAEQ   QA AAA AYEAAF ATVPPP IAANRA LMAL
Sbjct  65   ASASMAAAAAPYVAWLNTTAVQAEQTAVQAEAAAGAYEAAFGATVPPPVIAANRAQLMAL  124

Query  122  LATNFLGQNTAAIAATEAQYAEMWAQDAAAMYGYAGASAAATQLSPFNPAAQTINPAGLA  181
            +ATN LGQNT AIAATEAQY EMWAQDA AMYGYAG+SAAATQLSPF    Q  NP+GLA
Sbjct  125  IATNILGQNTPAIAATEAQYTEMWAQDAMAMYGYAGSSAAATQLSPFVEPQQATNPSGLA  184

Query  182  SQAASVGQAVSGAANAQA------LTDIPKALFGLSGIFTNEPPWLTDLGKALGLTGHTW  235
            +QAA+V +A + +A  Q+      ++ +P AL GLSG   N   WL  +   L  +G  W
Sbjct  185  AQAAAVTEASANSAGNQSSTLSGLISMVPSALQGLSG--PNSTSWLQVIWDLLTGSGPAW  242


>gi|296167733|ref|ZP_06849950.1| PPE family protein [Mycobacterium parascrofulaceum ATCC BAA-614]
 gi|295897076|gb|EFG76691.1| PPE family protein [Mycobacterium parascrofulaceum ATCC BAA-614]
Length=406

 Score =  214 bits (545),  Expect = 2e-53, Method: Compositional matrix adjust.
 Identities = 183/439 (42%), Positives = 230/439 (53%), Gaps = 59/439 (13%)

Query  1    MLDFAQLPPEVNSALMYAGPGSGPMLAAAAAWEALAAELQTTASTYDALITGLADGPWQG  60
            M+DF   PPE NSA MY GPG   + AAA+AW  LAAEL +TA  YD +IT L+   W G
Sbjct  1    MIDFGAAPPEYNSARMYTGPGPEALTAAASAWNGLAAELNSTALGYDKVITALSGEEWLG  60

Query  61   SSAASMVAAATPQVAWLRSTAGQAEQAGSQAVAAASAYEAAFFATVPPPEIAANRALLMA  120
             ++ASM  A  P VAW+R+TA QAEQ  +Q  AAA+AYE A  ATVPPP +AANRA    
Sbjct  61   PASASMAQAVAPYVAWMRTTAAQAEQTANQMHAAATAYETALAATVPPPLVAANRAQTAQ  120

Query  121  LLATNFLGQNTAAIAATEAQYAEMWAQDAAAMYGYAGASAAATQLSPFNPAAQTINPAGL  180
            LLATN LG NT AIA  EAQY EMWAQDA+ MY YAG SAAAT+++PF  A Q  NP+  
Sbjct  121  LLATNVLGLNTPAIAQLEAQYGEMWAQDASTMYSYAGQSAAATKVAPFTAAPQIANPSAQ  180

Query  181  ASQAASVGQAV--SGAANAQALTDIPKALFGLSGIFTNEPPWLTDLGKALGLTGHTWSSD  238
            A+Q  +V  A   S A++ Q++         LS   ++ P  L  L         T S+ 
Sbjct  181  ATQGTAVANATGNSAASSTQSV---------LSHAVSSTPNTLQALAAPAATQSSTTSAP  231

Query  239  GSG---LIVGGV-----LGDFVQGVTGSAEL--------DASVAMDTFGKWVSPARLMVT  282
             S    L+ G       LG FV G    + L          SV M  FG           
Sbjct  232  FSEIWYLLTGQTTLPTSLGSFVNGYNPFSALWYNTEGLPYFSVGMGNFG----------V  281

Query  283  QFKDYFGLAHDLPKWASEGAKAAGEAAKALP----AAVPAIPSAGLSGVAGAVGQAASVG  338
            Q     GL +            A  A KALP            A  +  A A+G AASVG
Sbjct  282  QIAKTTGLLNG-----------AAPAVKALPGLGGLGGLLGGGATAAHPAAALGNAASVG  330

Query  339  G-LKVPAVWTATTPAASPA-VLAASNGLGAAAAAEGSTHAFGGM--PLMGSGAGRAFNNF  394
            G L VP  W+A   A++PA VL  +  +   +AA  +T A G +   +  +GAG   +  
Sbjct  331  GRLSVPVSWSA---ASTPAPVLGQAIPVSTVSAAPDATAAPGNLLGGMPLAGAGAGGHAG  387

Query  395  AAPRYGFKPTVIAQPPAGG  413
              P+YGF+PTV+A+PP GG
Sbjct  388  VGPKYGFRPTVMARPPFGG  406


>gi|342861307|ref|ZP_08717955.1| PPE family protein [Mycobacterium colombiense CECT 3035]
 gi|342131207|gb|EGT84488.1| PPE family protein [Mycobacterium colombiense CECT 3035]
Length=417

 Score =  209 bits (533),  Expect = 5e-52, Method: Compositional matrix adjust.
 Identities = 176/439 (41%), Positives = 227/439 (52%), Gaps = 49/439 (11%)

Query  2    LDFAQLPPEVNSALMYAGPGSGPMLAAAAAWEALAAELQTTASTYDALITGLADGPWQGS  61
            +DF  LPPE+NS  MYAGPGSGPM+AAAAAW+ L AEL + AS Y ++I+ L   PW G 
Sbjct  1    MDFGALPPEINSGRMYAGPGSGPMMAAAAAWDGLGAELSSAASGYTSVISELTHAPWVGP  60

Query  62   SAASMVAAATPQVAWLRSTAGQAEQAGSQAVAAASAYEAAFFATVPPPEIAANRALLMAL  121
            +++SM++A TP V+WL   A QAE+   QA AAA+A+EAAF  TVPPP IAANR LL  L
Sbjct  61   ASSSMLSAVTPYVSWLSVLAAQAEETAGQARAAAAAFEAAFAMTVPPPVIAANRVLLANL  120

Query  122  LATNFLGQNTAAIAATEAQYAEMWAQDAAAMYGYAGASAAATQLSPFNPAAQTINPAGLA  181
            +ATNFLGQNT AIAATEAQY EMWAQDAAAMYGYAG+SA A++L P      T  P   +
Sbjct  121  VATNFLGQNTPAIAATEAQYMEMWAQDAAAMYGYAGSSAVASELPPLTSPPNTTTPEADS  180

Query  182  SQ-----------AASVGQAVSGAANAQALT---------DIPKALFGLSGIFTNEPPWL  221
             Q           A +  Q  S  A  QAL+                   G FT    WL
Sbjct  181  DQAAAVAKAVAEPAGNTAQTTSQLATPQALSAGATQAVTQASTTTTATQPGPFT----WL  236

Query  222  TDLGKALGLTGHTWSSDGSGLIVGGVLGDFVQGVTGSAELDASVAMDTFGKWVSPARLMV  281
             +L      +G    ++    +  G+ G  ++  TG A    S  + +F  W S A+ + 
Sbjct  237  QNLINGFLTSGLPTPTNNYAGLNTGMYGTLLKQTTGLAYF--STGITSF--WSSIAQQLT  292

Query  282  TQFKDYFGLA----HDLPKWASEGAKAAGEAAKALPAAVPAIPSAGLSGVAGAVGQAASV  337
                     A       P++AS G    G                 +  V+  VGQA  V
Sbjct  293  FGPGGTTAGAGGAWFPTPQFASLGLGNLGGVGH-------------VGAVSAGVGQAGRV  339

Query  338  GGLKVPAVWTATTPAASPAVLAASNGLGAAAAAEGSTHAFG---GMPLMGSGAGRAFNNF  394
            G L VP  W   T + SPA L+       AAA   ++ A G   GMP+ GS   R     
Sbjct  340  GMLSVPQHWATLTSSVSPAALSEEATPIQAAAGGANSPANGLLRGMPV-GSIGRRGAAAG  398

Query  395  AAPRYGFKPTVIAQPPAGG  413
               +YGF+ +V+ +PP+ G
Sbjct  399  YVNKYGFRYSVLTRPPSAG  417


>gi|240171463|ref|ZP_04750122.1| PPE family protein [Mycobacterium kansasii ATCC 12478]
Length=408

 Score =  209 bits (532),  Expect = 6e-52, Method: Compositional matrix adjust.
 Identities = 199/428 (47%), Positives = 250/428 (59%), Gaps = 36/428 (8%)

Query  2    LDFAQLPPEVNSALMYAGPGSGPMLAAAAAWEALAAELQTTASTYDALITGLADGPWQGS  61
            +D+A LPPEVNSA MY GPG GP+LAAA AW++L+ EL + A  Y  ++TG+  GPW+G 
Sbjct  1    MDYAALPPEVNSARMYTGPGCGPILAAALAWDSLSGELSSAAKEYSIVVTGMTSGPWRGP  60

Query  62   SAASMVAAATPQVAWLRSTAGQAEQAGSQAVAAASAYEAAFFATVPPPEIAANRALLMAL  121
            ++++M AA  P +AWL +TA QA QA  QA AAA+AYEAAF  TVPP EIAANRA L +L
Sbjct  61   ASSAMAAAVGPYIAWLATTASQAFQAAGQAKAAAAAYEAAFAMTVPPAEIAANRAQLASL  120

Query  122  LATNFLGQNTAAIAATEAQYAEMWAQDAAAMYGYAGASAAATQLSPFNPAAQTIN-PAGL  180
            +ATN LGQNT AIAATEA Y +MWAQDAAAMYGYA +SAAA+QL+PF  A  T +  AG 
Sbjct  121  VATNLLGQNTPAIAATEALYGQMWAQDAAAMYGYAASSAAASQLAPFADAPMTASGDAGA  180

Query  181  ASQAASVGQAVSGAANAQALTDIPKALFGL---SGIFTNEPPWLTDLGKAL----GLTGH  233
              QAAS     S  A +Q +  +P  L GL   +G  T     L  LG  +    GL+G 
Sbjct  181  LVQAASATSTASQGALSQVMQTVPATLQGLASPTGASTAGADLLGLLGSGMEDWIGLSGA  240

Query  234  TWSSDGSGLIVGGVLGDFVQGVTGSAELDASVAMDTFGK----WVSPARLMVTQFKDYFG  289
              SS        G+L  F+ G  GS  L  +++   F      + +P   + T   D  G
Sbjct  241  DLSSP------AGILA-FLSGTDGS-PLGVALSSVYFNALSSGFYTPGNFLGT-LADAVG  291

Query  290  LAHDLPKWASEGAKAAGEAAKALPAAVPAIPSAGLSGVAGAVGQAASVGGLKVPAVWTAT  349
            L     + A    +AA  AA+A  + + A        V+  VG AA++G L VP  WTAT
Sbjct  292  L-----QGAEAVEEAAAGAAEAAASELGAATGGVGGAVSAGVGNAATIGPLSVPPAWTAT  346

Query  350  TPAASPAVLAASNGLGAAAAAEGSTHA----FGGMPLMGSGAGRAFNNFAAPRYGFKPTV  405
            +   + A    SN   AAA A G T A     GGMPL G GA R F    APRYGF+PTV
Sbjct  347  SSLGAAASALPSN---AAATAPGITGATPSMLGGMPLSGLGA-RGFAE--APRYGFRPTV  400

Query  406  IAQPPAGG  413
            +  PPA G
Sbjct  401  MVHPPAAG  408


>gi|118617919|ref|YP_906251.1| PPE family protein [Mycobacterium ulcerans Agy99]
 gi|118570029|gb|ABL04780.1| PPE family protein [Mycobacterium ulcerans Agy99]
Length=382

 Score =  206 bits (525),  Expect = 4e-51, Method: Compositional matrix adjust.
 Identities = 184/417 (45%), Positives = 233/417 (56%), Gaps = 40/417 (9%)

Query  2    LDFAQLPPEVNSALMYAGPGSGPMLAAAAAWEALAAELQTTASTYDALITGLADGPWQGS  61
            +DF+ LPPEVNSA MY GPGSG +LAAAA+W+ALAAEL TTA T  +++TGL D  W+G 
Sbjct  1    MDFSLLPPEVNSARMYTGPGSGSLLAAAASWDALAAELGTTAETCGSILTGLTDLSWRGP  60

Query  62   SAASMVAAATPQVAWLRSTAGQAEQAGSQAVAAASAYEAAFFATVPPPEIAANRALLMAL  121
            ++ SM A+A P V WL  TA Q +QA  QA  AA A+E A+  TVPPP +AANRA L+ L
Sbjct  61   ASESMAASAAPCVGWLYRTAEQTQQAAIQARTAALAFEQAYAMTVPPPLVAANRAQLLVL  120

Query  122  LATNFLGQNTAAIAATEAQYAEMWAQDAAAMYGYAGASAAATQLSPFNPAAQTINPAGLA  181
            +ATNF GQNT+AIAA EAQYAEMWAQDAAAMYGYA  SAAA  L+PF+   Q  +PAGLA
Sbjct  121  IATNFFGQNTSAIAANEAQYAEMWAQDAAAMYGYATTSAAAGMLTPFSSPNQATSPAGLA  180

Query  182  SQAASVGQAVSGAANAQALTDIPKALFGLSGIFTNEPPWLTDLGKALGLTGHTWSSDGSG  241
            +Q+ +V QA + AA    +T +  +L    G     P  L D    L      +++ G  
Sbjct  181  AQSTAVTQANATAAATDPITQLVSSLTQSLGAIQAIPSILPDDFTILDGVFSAYATVG--  238

Query  242  LIVGGVLGDFVQGVTGSAELDASVAMDTFGKWVSPARLMVTQFKDYFGLAHDLPKWASEG  301
              V   +  F  GV G     A   +   G   +PA +  +     FGL   +   A   
Sbjct  239  --VTQDIESFCAGVIG-----AENNLGLIGSSENPAEVTPSD----FGLGSLISSTAPAS  287

Query  302  AKAAGEAAKALPAAVPAIPSAGL-SGVAGAVGQAASVGGLKVPAVWTA----TTPAASPA  356
            A + G                GL S VA +VG++ S+G L VP  W+A       A SP+
Sbjct  288  AASGG----------------GLGSAVAASVGRSGSIGQLSVPPSWSAPSARMVSALSPS  331

Query  357  VLAASNGLGAAAAAEGSTHAFGGMPLMGSGAGRAFNNFAAPRYGFKPTVIAQPPAGG  413
             L    G   AAAA   +  F GM  +   A RA      PRYG + TV+A PPA G
Sbjct  332  GLTTIPGTEEAAAA--GSPGFPGM--VAPPATRASGVL--PRYGVRLTVMAHPPAAG  382


>gi|183981528|ref|YP_001849819.1| PPE family protein, PPE51 [Mycobacterium marinum M]
 gi|183174854|gb|ACC39964.1| PPE family protein, PPE51 [Mycobacterium marinum M]
Length=382

 Score =  206 bits (525),  Expect = 4e-51, Method: Compositional matrix adjust.
 Identities = 184/417 (45%), Positives = 233/417 (56%), Gaps = 40/417 (9%)

Query  2    LDFAQLPPEVNSALMYAGPGSGPMLAAAAAWEALAAELQTTASTYDALITGLADGPWQGS  61
            +DF+ LPPEVNSA MY GPGSG +LAAAA+W+ALAAEL TTA T  +++TGL D  W+G 
Sbjct  1    MDFSLLPPEVNSARMYTGPGSGSLLAAAASWDALAAELGTTAETCGSILTGLTDLSWRGP  60

Query  62   SAASMVAAATPQVAWLRSTAGQAEQAGSQAVAAASAYEAAFFATVPPPEIAANRALLMAL  121
            ++ SM A+A P V WL  TA Q +QA  QA  AA A+E A+  TVPPP +AANRA L+ L
Sbjct  61   ASESMAASAAPYVGWLYRTAEQTQQAAIQARTAALAFEQAYAMTVPPPLVAANRAQLLVL  120

Query  122  LATNFLGQNTAAIAATEAQYAEMWAQDAAAMYGYAGASAAATQLSPFNPAAQTINPAGLA  181
            +ATNF GQNT+AIAA EAQYAEMWAQDAAAMYGYA  SAAA  L+PF+   Q  +PAGLA
Sbjct  121  IATNFFGQNTSAIAANEAQYAEMWAQDAAAMYGYATTSAAAGMLTPFSSPNQATSPAGLA  180

Query  182  SQAASVGQAVSGAANAQALTDIPKALFGLSGIFTNEPPWLTDLGKALGLTGHTWSSDGSG  241
            +Q+ +V QA + AA    +T +  +L    G     P  L D    L      +++ G  
Sbjct  181  AQSTAVTQANATAAATDPITQLVSSLTQSLGAIQAIPSILPDDFTILDGVFSAYATVG--  238

Query  242  LIVGGVLGDFVQGVTGSAELDASVAMDTFGKWVSPARLMVTQFKDYFGLAHDLPKWASEG  301
              V   +  F  GV G     A   +   G   +PA +  +     FGL   +   A   
Sbjct  239  --VTQDIESFCAGVIG-----AENNLGLIGSSENPAEVTPSD----FGLGSLISSTAPAS  287

Query  302  AKAAGEAAKALPAAVPAIPSAGL-SGVAGAVGQAASVGGLKVPAVWTA----TTPAASPA  356
            A + G                GL S VA +VG++ S+G L VP  W+A       A SP+
Sbjct  288  AASGG----------------GLGSAVAASVGRSGSIGQLSVPPSWSAPSARMVSALSPS  331

Query  357  VLAASNGLGAAAAAEGSTHAFGGMPLMGSGAGRAFNNFAAPRYGFKPTVIAQPPAGG  413
             L    G   AAAA   +  F GM  +   A RA      PRYG + TV+A PPA G
Sbjct  332  GLTTIPGTEEAAAA--GSPGFPGM--VAPPATRASGVL--PRYGVRLTVMAHPPAAG  382


>gi|296170357|ref|ZP_06851948.1| PPE family protein [Mycobacterium parascrofulaceum ATCC BAA-614]
 gi|295895080|gb|EFG74799.1| PPE family protein [Mycobacterium parascrofulaceum ATCC BAA-614]
Length=459

 Score =  206 bits (525),  Expect = 5e-51, Method: Compositional matrix adjust.
 Identities = 181/391 (47%), Positives = 222/391 (57%), Gaps = 55/391 (14%)

Query  2    LDFAQLPPEVNSALMYAGPGSGPMLAAAAAWEALAAELQTTASTYDALITGLADGPWQGS  61
            +D+  LPPE+NSA MYAGPGSG ML AAAAW+ LA EL++ A++Y A+I+GL    W G 
Sbjct  1    MDYGVLPPEINSARMYAGPGSGSMLTAAAAWDELATELRSIAASYSAVISGLTTA-WLGP  59

Query  62   SAASMVAAATPQVAWLRSTAGQAEQAGSQAVAAASAYEAAFFATVPPPEIAANRALLMAL  121
            S+  M AAA P  AWL +TA QAEQ+GSQA AAA+AYEAAF ATVPPP I  NRA L +L
Sbjct  60   SSTRMAAAAAPYAAWLNATAAQAEQSGSQARAAAAAYEAAFAATVPPPVIETNRAELESL  119

Query  122  LATNFLGQNTAAIAATEAQYAEMWAQDAAAMYGYAGASAAATQLSPFNPAAQTINPAGLA  181
            +ATN  GQNTAAIAA EA+YA MWAQDAAAMYGYAG SAAA  ++PF+P AQ  NPAG A
Sbjct  120  IATNTFGQNTAAIAANEARYARMWAQDAAAMYGYAGQSAAAAAVTPFDPPAQNTNPAGTA  179

Query  182  SQAASVGQAV--SGAANAQA----LTD-IPKALFGLSGIFTNEPPWLTDLGKALGLTGHT  234
             Q A+V Q V  S   N+QA    LT   P AL  L+      PP  + L   L     +
Sbjct  180  GQTAAVSQVVGTSAGTNSQAALSHLTSATPSALRSLAAPAAVNPPSASSLASFLSSLNSS  239

Query  235  WSSDGSGLIVGGVLGDFVQGVTGSAELDASVAMDTFGKWVSPARLMVTQFKDYFGLAHDL  294
              +                 + G+ EL          K V PA  ++       GL    
Sbjct  240  PLAK----------------LAGNVEL--------IPKAVLPANDVL--ISTIMGLV---  270

Query  295  PKWASEGAKAAGEAAKALPAAVPAIPSAGL--------SGVAGAVGQAASVGGLKVPAVW  346
                  GA+  G+   A+ AA P + +AGL        S V+  VGQA  VGGL VP  W
Sbjct  271  -----IGARHLGDLTVAVKAATPGL-AAGLGYAAPALGSTVSATVGQAGLVGGLAVPPSW  324

Query  347  TATTPAASP--AVLA--ASNGLGAAAAAEGS  373
               TPA     AVL+  + + + AA  +EGS
Sbjct  325  AVATPAIRTVAAVLSGTSESAVAAATVSEGS  355


>gi|167967397|ref|ZP_02549674.1| PPE family protein [Mycobacterium tuberculosis H37Ra]
 gi|253799148|ref|YP_003032149.1| PPE family protein [Mycobacterium tuberculosis KZN 1435]
 gi|254231990|ref|ZP_04925317.1| PPE family protein [Mycobacterium tuberculosis C]
 24 more sequence titles
 Length=410

 Score =  206 bits (523),  Expect = 7e-51, Method: Compositional matrix adjust.
 Identities = 122/178 (69%), Positives = 140/178 (79%), Gaps = 0/178 (0%)

Query  1    MLDFAQLPPEVNSALMYAGPGSGPMLAAAAAWEALAAELQTTASTYDALITGLADGPWQG  60
            MLDF  LPPE+NS  MYAGPGSGP+LAAAAAW+ALAAEL + A++Y + I GL   PW G
Sbjct  1    MLDFGALPPEINSGRMYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMG  60

Query  61   SSAASMVAAATPQVAWLRSTAGQAEQAGSQAVAAASAYEAAFFATVPPPEIAANRALLMA  120
             S+ +M AA  P VAW+  TAGQAEQAG+QA  AA  YE AF ATVPPP I ANRALLM+
Sbjct  61   PSSITMAAAVAPYVAWISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMS  120

Query  121  LLATNFLGQNTAAIAATEAQYAEMWAQDAAAMYGYAGASAAATQLSPFNPAAQTINPA  178
            L+ATN  GQNT AIAATEA YAEMWAQDAAAMYGYAG+SA A+QL+PF+   QT NP+
Sbjct  121  LVATNIFGQNTPAIAATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPS  178


>gi|294996719|ref|ZP_06802410.1| PPE family protein [Mycobacterium tuberculosis 210]
 gi|13377907|gb|AAK20893.1| Rv1808-like protein [Mycobacterium microti]
 gi|13377909|gb|AAK20894.1| Rv1808-like protein [Mycobacterium microti]
 gi|339294744|gb|AEJ46855.1| PPE family protein [Mycobacterium tuberculosis CCDC5079]
 gi|339298372|gb|AEJ50482.1| PPE family protein [Mycobacterium tuberculosis CCDC5180]
Length=410

 Score =  206 bits (523),  Expect = 8e-51, Method: Compositional matrix adjust.
 Identities = 122/178 (69%), Positives = 140/178 (79%), Gaps = 0/178 (0%)

Query  1    MLDFAQLPPEVNSALMYAGPGSGPMLAAAAAWEALAAELQTTASTYDALITGLADGPWQG  60
            MLDF  LPPE+NS  MYAGPGSGP+LAAAAAW+ALAAEL + A++Y + I GL   PW G
Sbjct  1    MLDFGALPPEINSGRMYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMG  60

Query  61   SSAASMVAAATPQVAWLRSTAGQAEQAGSQAVAAASAYEAAFFATVPPPEIAANRALLMA  120
             S+ +M AA  P VAW+  TAGQAEQAG+QA  AA  YE AF ATVPPP I ANRALLM+
Sbjct  61   PSSITMAAAVAPYVAWISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMS  120

Query  121  LLATNFLGQNTAAIAATEAQYAEMWAQDAAAMYGYAGASAAATQLSPFNPAAQTINPA  178
            L+ATN  GQNT AIAATEA YAEMWAQDAAAMYGYAG+SA A+QL+PF+   QT NP+
Sbjct  121  LVATNIFGQNTPAIAATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPS  178


>gi|308372058|ref|ZP_07427232.2| putative PPE family protein [Mycobacterium tuberculosis SUMu004]
 gi|308334577|gb|EFP23428.1| putative PPE family protein [Mycobacterium tuberculosis SUMu004]
Length=399

 Score =  206 bits (523),  Expect = 8e-51, Method: Compositional matrix adjust.
 Identities = 122/178 (69%), Positives = 140/178 (79%), Gaps = 0/178 (0%)

Query  1    MLDFAQLPPEVNSALMYAGPGSGPMLAAAAAWEALAAELQTTASTYDALITGLADGPWQG  60
            MLDF  LPPE+NS  MYAGPGSGP+LAAAAAW+ALAAEL + A++Y + I GL   PW G
Sbjct  1    MLDFGALPPEINSGRMYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMG  60

Query  61   SSAASMVAAATPQVAWLRSTAGQAEQAGSQAVAAASAYEAAFFATVPPPEIAANRALLMA  120
             S+ +M AA  P VAW+  TAGQAEQAG+QA  AA  YE AF ATVPPP I ANRALLM+
Sbjct  61   PSSITMAAAVAPYVAWISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMS  120

Query  121  LLATNFLGQNTAAIAATEAQYAEMWAQDAAAMYGYAGASAAATQLSPFNPAAQTINPA  178
            L+ATN  GQNT AIAATEA YAEMWAQDAAAMYGYAG+SA A+QL+PF+   QT NP+
Sbjct  121  LVATNIFGQNTPAIAATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPS  178


>gi|183982688|ref|YP_001850979.1| PPE family protein, PPE31_1 [Mycobacterium marinum M]
 gi|183176014|gb|ACC41124.1| PPE family protein, PPE31_1 [Mycobacterium marinum M]
Length=422

 Score =  205 bits (521),  Expect = 1e-50, Method: Compositional matrix adjust.
 Identities = 180/435 (42%), Positives = 241/435 (56%), Gaps = 36/435 (8%)

Query  2    LDFAQLPPEVNSALMYAGPGSGPMLAAAAAWEALAAELQTTASTYDALITGLADGPWQGS  61
            +DFA LPPE+NS  MY+GPGS PMLAA  AW+ LAAEL++TA+ Y+ +I  L    W G 
Sbjct  1    MDFAALPPEINSIRMYSGPGSAPMLAAVTAWDGLAAELRSTAAAYETVIAVLTGDGWLGP  60

Query  62   SAASMVAAATPQVAWLRSTAGQAEQAGSQAVAAASAYEAAFFATVPPPEIAANRALLMAL  121
            ++ SM AA  P +AW+  T  QAEQ   QA AAA A+EAAF  TVPP ++AANR  L  L
Sbjct  61   ASESMEAAVFPYLAWMNITGMQAEQTARQAAAAAGAFEAAFAMTVPPAQVAANRTQLQTL  120

Query  122  LATNFLGQNTAAIAATEAQYAEMWAQDAAAMYGYAGASAAATQLSPFNPAAQTINPAGLA  181
            +ATN LGQNT AIAATEA Y EMWAQDAAAMYGYA  SAAA+ L+ F   AQT +P+GLA
Sbjct  121  VATNLLGQNTPAIAATEAAYGEMWAQDAAAMYGYAVGSAAASTLTQFTQPAQTTDPSGLA  180

Query  182  SQAASVGQAVSGAANAQALTDIPKALFGLSGIFTNEPPWLTDLGKALGLTGHTWSSDGSG  241
            SQ+A+V QAV         T++P+       + +  P  L  L      +    +  GSG
Sbjct  181  SQSAAVTQAVGSTVGNLTQTELPQ-------LMSAVPASLQGLASPAAASPID-AIPGSG  232

Query  242  LIVGGVLGDFVQGVTGSAE---LDASVAMDTF--GKWVSPARL---MVTQFKDYFGLAHD  293
            L+    L +F+ G  G+     L++S+ ++ F    +VSPA +   +     D   +A  
Sbjct  233  LL--AALLNFLDGNDGNPYGVFLNSSL-VNGFVSAGYVSPAVVGPAIWAAMADINAVALG  289

Query  294  LPKWASEGAKAAGEAAKA-LPAAVPAIPSA------------GLSGVAGAVGQAASVGGL  340
              + A+     +GE   + +PAA PA P +            G  G++  + QA  VG +
Sbjct  290  AQESAAVPPMGSGEGNPSWIPAASPASPESLPVLGEETAATLGTGGISAGMNQAELVGRM  349

Query  341  KVPAVW-TATTPAASPAVLAASNGLGAAAAAEGSTHAFGGMPLMGSGA-GRAFNNFAAPR  398
             VP  W  AT  A      A   G  + A    +     G+P M +G  G    N  APR
Sbjct  350  SVPQSWGVATAVANHAGAAAPGGGWTSTAVVPEAAVGMPGIPGMPAGIYGHNLGN--APR  407

Query  399  YGFKPTVIAQPPAGG  413
            YGF+PT++ +PPA G
Sbjct  408  YGFRPTIMGRPPAAG  422


>gi|307084423|ref|ZP_07493536.1| putative PPE family protein [Mycobacterium tuberculosis SUMu012]
 gi|308365983|gb|EFP54834.1| putative PPE family protein [Mycobacterium tuberculosis SUMu012]
Length=336

 Score =  204 bits (520),  Expect = 2e-50, Method: Compositional matrix adjust.
 Identities = 122/178 (69%), Positives = 140/178 (79%), Gaps = 0/178 (0%)

Query  1    MLDFAQLPPEVNSALMYAGPGSGPMLAAAAAWEALAAELQTTASTYDALITGLADGPWQG  60
            MLDF  LPPE+NS  MYAGPGSGP+LAAAAAW+ALAAEL + A++Y + I GL   PW G
Sbjct  1    MLDFGALPPEINSGRMYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMG  60

Query  61   SSAASMVAAATPQVAWLRSTAGQAEQAGSQAVAAASAYEAAFFATVPPPEIAANRALLMA  120
             S+ +M AA  P VAW+  TAGQAEQAG+QA  AA  YE AF ATVPPP I ANRALLM+
Sbjct  61   PSSITMAAAVAPYVAWISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMS  120

Query  121  LLATNFLGQNTAAIAATEAQYAEMWAQDAAAMYGYAGASAAATQLSPFNPAAQTINPA  178
            L+ATN  GQNT AIAATEA YAEMWAQDAAAMYGYAG+SA A+QL+PF+   QT NP+
Sbjct  121  LVATNIFGQNTPAIAATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPS  178


>gi|31792997|ref|NP_855490.1| PPE family protein [Mycobacterium bovis AF2122/97]
 gi|121637710|ref|YP_977933.1| PPE family protein [Mycobacterium bovis BCG str. Pasteur 1173P2]
 gi|224990194|ref|YP_002644881.1| PPE family protein [Mycobacterium bovis BCG str. Tokyo 172]
 29 more sequence titles
 Length=409

 Score =  202 bits (515),  Expect = 6e-50, Method: Compositional matrix adjust.
 Identities = 120/177 (68%), Positives = 139/177 (79%), Gaps = 0/177 (0%)

Query  2    LDFAQLPPEVNSALMYAGPGSGPMLAAAAAWEALAAELQTTASTYDALITGLADGPWQGS  61
            +DF  LPPE+NS  MYAGPGSGP+LAAAAAW+ALAAEL + A++Y + I GL   PW G 
Sbjct  1    MDFGALPPEINSGRMYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGP  60

Query  62   SAASMVAAATPQVAWLRSTAGQAEQAGSQAVAAASAYEAAFFATVPPPEIAANRALLMAL  121
            S+ +M AA  P VAW+  TAGQAEQAG+QA  AA  YE AF ATVPPP I ANRALLM+L
Sbjct  61   SSITMAAAVAPYVAWISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSL  120

Query  122  LATNFLGQNTAAIAATEAQYAEMWAQDAAAMYGYAGASAAATQLSPFNPAAQTINPA  178
            +ATN  GQNT AIAATEA YAEMWAQDAAAMYGYAG+SA A+QL+PF+   QT NP+
Sbjct  121  VATNIFGQNTPAIAATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPS  177


>gi|57116921|ref|YP_177844.1| PPE family protein [Mycobacterium tuberculosis H37Rv]
 gi|148661614|ref|YP_001283137.1| PPE family protein [Mycobacterium tuberculosis H37Ra]
 gi|148823021|ref|YP_001287775.1| PPE family protein [Mycobacterium tuberculosis F11]
 9 more sequence titles
 Length=409

 Score =  202 bits (515),  Expect = 7e-50, Method: Compositional matrix adjust.
 Identities = 120/177 (68%), Positives = 139/177 (79%), Gaps = 0/177 (0%)

Query  2    LDFAQLPPEVNSALMYAGPGSGPMLAAAAAWEALAAELQTTASTYDALITGLADGPWQGS  61
            +DF  LPPE+NS  MYAGPGSGP+LAAAAAW+ALAAEL + A++Y + I GL   PW G 
Sbjct  1    MDFGALPPEINSGRMYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGP  60

Query  62   SAASMVAAATPQVAWLRSTAGQAEQAGSQAVAAASAYEAAFFATVPPPEIAANRALLMAL  121
            S+ +M AA  P VAW+  TAGQAEQAG+QA  AA  YE AF ATVPPP I ANRALLM+L
Sbjct  61   SSITMAAAVAPYVAWISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSL  120

Query  122  LATNFLGQNTAAIAATEAQYAEMWAQDAAAMYGYAGASAAATQLSPFNPAAQTINPA  178
            +ATN  GQNT AIAATEA YAEMWAQDAAAMYGYAG+SA A+QL+PF+   QT NP+
Sbjct  121  VATNIFGQNTPAIAATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPS  177


>gi|183982690|ref|YP_001850981.1| PPE family protein, PPE31 [Mycobacterium marinum M]
 gi|183176016|gb|ACC41126.1| PPE family protein, PPE31 [Mycobacterium marinum M]
Length=386

 Score =  202 bits (514),  Expect = 1e-49, Method: Compositional matrix adjust.
 Identities = 181/424 (43%), Positives = 226/424 (54%), Gaps = 54/424 (12%)

Query  2    LDFAQLPPEVNSALMYAGPGSGPMLAAAAAWEALAAELQTTASTYDALITGLADGPWQGS  61
            LDFA LPPE+NSA MY+GPGS PMLAAA+AW+ LAAEL+ T  +YD+++  L    W G 
Sbjct  5    LDFATLPPEINSARMYSGPGSAPMLAAASAWKGLAAELRVTVLSYDSVLRALTGEEWYGP  64

Query  62   SAASMVAAATPQVAWLRSTAGQAEQAGSQAVAAASAYEAAFFATVPPPEIAANRALLMAL  121
            ++ASM AAA P VAW+ +TA QAE++  QA AAA+AYEAAF ATV P  I ANRA LM L
Sbjct  65   ASASMAAAAAPYVAWMSTTAAQAEESAVQAAAAAAAYEAAFSATVAPTVITANRAQLMVL  124

Query  122  LATNFLGQNTAAIAATEAQYAEMWAQDAAAMYGYAGASAAATQLSPFNPAAQTINPAGLA  181
            +ATN LGQNT AIAA EAQY EMWAQDA AMYGYAG+SAAAT+LS F       NPAGL 
Sbjct  125  VATNVLGQNTPAIAAVEAQYCEMWAQDAMAMYGYAGSSAAATRLSEFLEPQHNTNPAGLL  184

Query  182  SQAASVGQAVSGAANA-QALTDIPKALFGLSGIFT-----NEPPWLTDLGKALGLTGHTW  235
            +Q +++ Q +S   N  Q L     +    SG+ +     N   WL  L    G   + W
Sbjct  185  AQQSTLAQLMSAVPNVLQGLASSNTSASAPSGLLSTLLSGNGQSWLATLWSEFGPNANIW  244

Query  236  SSDGSGLIVGGVLGDFVQGVTGSAELDASVAMDTFGKWVSPARLMVTQFKDYFG----LA  291
            ++  S               TG               ++ P+  MVT F    G      
Sbjct  245  NTIAS---------------TG---------------FLLPSN-MVTPFLGMLGTAAVAD  273

Query  292  HDLPKWASEGAKAAGEAAKALPAAVPAIPSAGLSGVAGAVGQAASVGGLKVPAVWTATTP  351
                   + G+ A G A  A   +V        +G A  VG+      L VP  WT   P
Sbjct  274  AAEDALGTTGSGALGGALSAPLGSVGGQAGLAAAGNAAIVGK------LSVPPSWTGAAP  327

Query  352  AASPAVLAASNGLGAAAAAEGSTHAFGGMP--LMGSGAGRAFNNFAAPRYGFKPTVIAQP  409
             ASP      + LG          A  GMP    G+ AG+ F   A P+YGF+PT +A+P
Sbjct  328  LASP----LGSALGGTPMVAPPPTAAAGMPGVPFGNMAGQPFGR-ALPQYGFRPTFVARP  382

Query  410  PAGG  413
            PA G
Sbjct  383  PAAG  386


>gi|306782177|ref|ZP_07420514.1| PPE family protein [Mycobacterium tuberculosis SUMu002]
 gi|306790362|ref|ZP_07428684.1| PPE family protein [Mycobacterium tuberculosis SUMu004]
 gi|306794889|ref|ZP_07433191.1| PPE family protein [Mycobacterium tuberculosis SUMu005]
 gi|308325139|gb|EFP13990.1| PPE family protein [Mycobacterium tuberculosis SUMu002]
 gi|308333218|gb|EFP22069.1| PPE family protein [Mycobacterium tuberculosis SUMu004]
 gi|308336675|gb|EFP25526.1| PPE family protein [Mycobacterium tuberculosis SUMu005]
Length=380

 Score =  201 bits (512),  Expect = 1e-49, Method: Compositional matrix adjust.
 Identities = 178/423 (43%), Positives = 229/423 (55%), Gaps = 54/423 (12%)

Query  2    LDFAQLPPEVNSALMYAGPGSGPMLAAAAAWEALAAELQTTASTYDALITGLADGPWQGS  61
            +DFA LPPEVNSA MY GPG+G +LAAA  W++LAAEL TTA  Y ++++GLA   W+G 
Sbjct  1    MDFALLPPEVNSARMYTGPGAGSLLAAAGGWDSLAAELATTAEAYGSVLSGLAALHWRGP  60

Query  62   SAASMVAAATPQVAWLRSTAGQAEQAGSQAVAAASAYEAAFFATVPPPEIAANRALLMAL  121
            +A SM   A P + WL +TA + +Q   QA AAA A+E A+  T+PPP +AANR  L+AL
Sbjct  61   AAESMAVTAAPYIGWLYTTAEKTQQTAIQARAAALAFEQAYAMTLPPPVVAANRIQLLAL  120

Query  122  LATNFLGQNTAAIAATEAQYAEMWAQDAAAMYGYAGASAAATQLSPFNPAAQTINPAGLA  181
            +ATNF GQNTAAIAATEAQYAEMWAQDAAAMYGYA ASAAA  L+PF+P  QT NPAGL 
Sbjct  121  IATNFFGQNTAAIAATEAQYAEMWAQDAAAMYGYATASAAAALLTPFSPPRQTTNPAGLT  180

Query  182  SQAASVGQA-------VSGAANA-QALTD---IPKALFGLSGIFTNEPPWLTDLGKALGL  230
            +QAA+V QA       +  A  A QALT    IP+    L  IF                
Sbjct  181  AQAAAVSQATDPLSLLIETATQALQALTIPSFIPEDFTFLDAIF----------------  224

Query  231  TGHTWSSDGSGLIVGGVLGDFVQGVTGSAELDASVAMDTFGKWVSPARLMVTQFKDYFGL  290
                     +G    GV  D    V G+   ++++ +   G   +PA +        FG+
Sbjct  225  ---------AGYATVGVTQDVESFVAGTIGAESNLGLLNVGD-ENPAEVT----PGDFGI  270

Query  291  AHDLPKWASEGAKAAGEAAKALPAAVPAIPSAGLSGVAGAVGQAASVGGLKVPAVWTATT  350
               +   +  G  +A  A  A       + S G    A ++GQ      L VP  W A  
Sbjct  271  GELVSATSPGGGVSASGAGGAASVGNTVLASVGR---ANSIGQ------LSVPPSWAA--  319

Query  351  PAASPAVLAASNGLGAAAAAEGSTHAFGGMPLMGSGAGRAFNNFAAPRYGFKPTVIAQPP  410
            P+  P    +  GL      + + H   G+P +   AGRA      PRYG + TV+A PP
Sbjct  320  PSTRPVSALSPAGLTTLPGTDVAEHGMPGVPGVPVAAGRASGVL--PRYGVRLTVMAHPP  377

Query  411  AGG  413
            A G
Sbjct  378  AAG  380


>gi|15843090|ref|NP_338127.1| PPE family protein [Mycobacterium tuberculosis CDC1551]
 gi|13883435|gb|AAK47941.1| PPE family protein [Mycobacterium tuberculosis CDC1551]
Length=393

 Score =  197 bits (502),  Expect = 2e-48, Method: Compositional matrix adjust.
 Identities = 176/422 (42%), Positives = 234/422 (56%), Gaps = 38/422 (9%)

Query  1    MLDFAQLPPEVNSALMYAGPGSGPMLAAAAAWEALAAELQTTASTYDALITGLADGPWQG  60
            M+DF  LPPE+NSA MYAGPGS  ++AAA  W+++A++L + AS + +++ GL  G W G
Sbjct  1    MVDFGALPPEINSARMYAGPGSASLVAAAKMWDSVASDLFSAASAFQSVVWGLTTGSWIG  60

Query  61   SSAASMVAAATPQVAWLRSTAGQAEQAGSQAVAAASAYEAAFFATVPPPEIAANRALLMA  120
            SSA  MVAAA+P VAW+  TAGQAE   +Q   AA+AYE A+  TVPPP IA NRA LM 
Sbjct  61   SSAGLMVAAASPYVAWMSVTAGQAELTAAQVRVAAAAYETAYGLTVPPPVIAENRAELMI  120

Query  121  LLATNFLGQNTAAIAATEAQYAEMWAQDAAAMYGYAGASAAATQ-LSPFNPAAQTINPAG  179
            L+ATN LGQNT AIA  EA+Y EMWAQDAAAM+GYA A+A AT+ L PF  A    NP G
Sbjct  121  LIATNLLGQNTPAIAVNEAEYGEMWAQDAAAMFGYAAATATATEALLPFEDAPLITNPGG  180

Query  180  LASQAASVGQAVSGAANAQALTDIPKALFGLSGIFTNEPPW--LTDLGKALGLTGHTWSS  237
            L  QA +V +A+  AA  Q + ++P+AL  L+    +  P+  L++L KA+  + H    
Sbjct  181  LLEQAVAVEEAIDTAAANQLMNNVPQALQQLAQPTKSIWPFDQLSELWKAI--SPHL---  235

Query  238  DGSGLIVGGVLGDFVQGVTGSAELDASVAMDTFGKWVSPARLMVTQFKDYFGLAHDLPKW  297
                      L + V      + L+  V+M   G  VS A  + +  K +       P  
Sbjct  236  --------SPLSNIV------SMLNNHVSMTNSG--VSMASTLHSMLKGFA------PAA  273

Query  298  ASEGAKAAGEAAKALPAAVPAIPSAGL-----SGVAGAVGQAASVGGLKVPAVWTATTPA  352
            A     AA    +A+ +    + S+       +GVA  +G+AASVG L VP  W A   A
Sbjct  274  AQAVETAAZNGVQAMSSLGSQLGSSLGSSGLGAGVAANLGRAASVGSLSVPQAWAAANQA  333

Query  353  ASPAVLAASNGLGAAAAAEGSTHAFGGMPLMGS-GAGRAFNNFAAPRYGFKPTVIAQPPA  411
             +PA  A       +AA     H  GG+PL  S  AG   NN  A R   +   I + PA
Sbjct  334  VTPAARALPLTSLTSAAQTAPGHMLGGLPLGHSVNAGSGINN--ALRVPARAYAIPRTPA  391

Query  412  GG  413
             G
Sbjct  392  AG  393


>gi|240169314|ref|ZP_04747973.1| PPE family protein [Mycobacterium kansasii ATCC 12478]
Length=383

 Score =  196 bits (498),  Expect = 6e-48, Method: Compositional matrix adjust.
 Identities = 177/425 (42%), Positives = 222/425 (53%), Gaps = 57/425 (13%)

Query  2    LDFAQLPPEVNSALMYAGPGSGPMLAAAAAWEALAAELQTTASTYDALITGLADGPWQGS  61
            +DF  LPPEVNS  MYAGPG G + AAA  W++LAAEL  TA  Y ++I GL  G W G 
Sbjct  1    MDFGALPPEVNSVRMYAGPGPGSLAAAAGMWDSLAAELHATAGHYRSVIAGLTSGRWLGP  60

Query  62   SAASMVAAATPQVAWLRSTAGQAEQAGSQAVAAASAYEAAFFATVPPPEIAANRALLMAL  121
            ++ SM +A  P VAW    A +A +  SQAV A   YEAAF  TVPPP +AANRALL AL
Sbjct  61   ASLSMASALGPYVAWTAGVAARAAETASQAVLAVEGYEAAFAMTVPPPVVAANRALLAAL  120

Query  122  LATNFLGQNTAAIAATEAQYAEMWAQDAAAMYGYAGASAAATQLSPFNPAAQTINPAGLA  181
            +ATNF GQN+ AIAATEA+Y  MWAQDAAAMY YA  SA A +L+      + INP GLA
Sbjct  121  VATNFFGQNSTAIAATEAEYGVMWAQDAAAMYEYAANSATACELTLLISPPEVINPVGLA  180

Query  182  SQAASVGQAVSGAANAQALTDIPKALFGLSGIFTNEPPWLTDLGKALGLTGHTWSSDGSG  241
             Q+ +V  A + +   Q           L+G+ ++ P  L  L   L             
Sbjct  181  GQSTAVAHAAAASGAEQ---------LSLAGLVSSVPAMLDGLASPL-------------  218

Query  242  LIVGGVLGDFVQGVTGSAELDASV--AMDTFGKWVSPARLM-----VTQFKDYFGLAHDL  294
                          +G AE  +S+   + T   +  P+  M     +       G+A   
Sbjct  219  --------------SGLAESSSSLMPTLATVPVYALPSYFMAAATPLYSLSSILGMAQTA  264

Query  295  PKWASEGAKAAGEAAKALPAAVPA----IPSAGLSGVAGAVGQAASVGGLKVPAVWTATT  350
               AS  A AA  AA+    AV +    I S G  GV G++G AAS+G L VPA WT+  
Sbjct  265  QGLASGAAAAAQAAAEGAAGAVSSGAGLIASVG-PGVVGSMGNAASLGPLSVPASWTSVI  323

Query  351  PAASPAVLAA-SNGLGAAAAAEGSTHAFGGMPLMG-SGAGRAFNNFAAPRYGFKPTVIAQ  408
            P A+    AA  NGL AA AA       G  P  G +G GR+      PRYG  PTV+ +
Sbjct  324  PTANMGAAAALPNGLDAANAAP---SLLGAAPRSGLTGPGRSVG----PRYGIVPTVMTR  376

Query  409  PPAGG  413
            PPA G
Sbjct  377  PPAAG  381


>gi|212595976|gb|ACJ35541.1| PPE16 [Mycobacterium avium subsp. avium]
Length=392

 Score =  194 bits (493),  Expect = 2e-47, Method: Compositional matrix adjust.
 Identities = 159/354 (45%), Positives = 199/354 (57%), Gaps = 30/354 (8%)

Query  2    LDFAQLPPEVNSALMYAGPGSGPMLAAAAAWEALAAELQTTASTYDALITGLADGPWQGS  61
            +DFA LPPEVNSA MYAGPGSGPMLAAA AW+ LAA L +TA +Y A IT L  GPW G 
Sbjct  1    MDFAVLPPEVNSARMYAGPGSGPMLAAAMAWDELAATLHSTADSYQAEITALTSGPWVGP  60

Query  62   SAASMVAAATPQVAWLRSTAGQAEQAGSQAVAAASAYEAAFFATVPPPEIAANRALLMAL  121
            SAA+M+AA TP + W+R+T  QAE+  + A AAA AYE AF  TVPPP + ANR LL  L
Sbjct  61   SAAAMIAAITPYLTWMRTTGAQAEETANNARAAAFAYETAFAETVPPPVVTANRTLLAQL  120

Query  122  LATNFLGQNTAAIAATEAQYAEMWAQDAAAMYGYAGASAAATQLSPFNPAAQTINPAGLA  181
            +ATN LGQNT AIA TEA+YAEMWA+DAAAMYGYAGA+AAAT+L+PF     T N     
Sbjct  121  VATNILGQNTPAIATTEAEYAEMWARDAAAMYGYAGAAAAATRLTPFTQPDPTTNSGADQ  180

Query  182  SQAASVGQAVSGAANAQALTDIPKALFGLSGIFTNEPPWLTDLGKALGLTGHTWSSDGSG  241
            SQA S   A +  +    +T  P         F+  P  L +L  +    G     D S 
Sbjct  181  SQAVSKAAATAAGSTRNTVTQQP---------FSAVPNMLNNLAVSPNALG-----DPSV  226

Query  242  LIVGGVLGDFVQGVTGSAELDASVAMDTFGKWVSPARLMVTQFK-----DYFGLAHDLPK  296
              + G+  D +     +  LDA  ++   G   +P+  +   F        F     +  
Sbjct  227  TDLLGLESDLI-----AIFLDAPASVVGMGV-DAPSATIALPFDIAGALTGFHTDDIVSG  280

Query  297  WASEGAKAAGEAAKALPAAVPAI--PSAGLSGVAGA-VGQAASVGGLKVPAVWT  347
            WA  G +         P+  P I  P+ G   +A A +GQA +VG L VP  WT
Sbjct  281  WA--GVQPWPGTGAVPPSPFPVITNPAGGFGTLASAGLGQAKTVGTLSVPPTWT  332


>gi|118466099|ref|YP_881935.1| PPE family protein [Mycobacterium avium 104]
 gi|118167386|gb|ABK68283.1| ppe family protein [Mycobacterium avium 104]
Length=461

 Score =  194 bits (493),  Expect = 3e-47, Method: Compositional matrix adjust.
 Identities = 161/358 (45%), Positives = 197/358 (56%), Gaps = 38/358 (10%)

Query  2    LDFAQLPPEVNSALMYAGPGSGPMLAAAAAWEALAAELQTTASTYDALITGLADGPWQGS  61
            +DFA LPPEVNSA MYAGPGSGPMLAAA AW+ LAA L +TA +Y A IT L  GPW G 
Sbjct  1    MDFAVLPPEVNSARMYAGPGSGPMLAAAMAWDELAATLHSTADSYQAEITALTSGPWVGP  60

Query  62   SAASMVAAATPQVAWLRSTAGQAEQAGSQAVAAASAYEAAFFATVPPPEIAANRALLMAL  121
            SAA+M+AA TP + W+R+T  QAE+  + A AAA AYE AF  TVPPP + ANR LL  L
Sbjct  61   SAAAMIAAITPYLTWMRTTGAQAEETANNARAAAFAYETAFAETVPPPVVTANRTLLAQL  120

Query  122  LATNFLGQNTAAIAATEAQYAEMWAQDAAAMYGYAGASAAATQLSPFNPAAQTINPAGLA  181
            +ATN LGQNT AIA TEA+YAEMWA+DAAAMYGYAGA+AAAT+L+PF     T N     
Sbjct  121  VATNILGQNTPAIATTEAEYAEMWARDAAAMYGYAGAAAAATRLTPFTQPDPTTNSGADQ  180

Query  182  SQAASVGQ-----AVSGAANAQALTDIPKALFGLSGIFTNE--PPWLTDLGKALGLTGHT  234
            SQA S        +       Q  + +P  L  L+ +  N    P +TDL   LGL    
Sbjct  181  SQAVSKAAATAAGSTRNTVTQQPFSAVPNMLNNLA-VSPNALGDPSVTDL---LGLESDL  236

Query  235  WSS--DGSGLIVGGVLGDFVQGVTGSAELDASVAMDTFGKWVSPARLMVTQFKDYFGLAH  292
             +   D    +VG  +G      T +   D + A+  F               D      
Sbjct  237  IAIFLDAPASVVG--MGVDAPSATIALPFDIAGALTGF------------HTDDIVSGWA  282

Query  293  DLPKWASEGAKAAGEAAKALPAAVPAI--PSAGLSGVAGA-VGQAASVGGLKVPAVWT  347
             +  W   GA          P+  P I  P+ G   +A A +GQA +VG L VP  WT
Sbjct  283  GVQPWPGTGAVP--------PSPFPVITNPAGGFGTLASAGLGQAKTVGTLSVPPTWT  332


>gi|57116920|ref|YP_177653.1| PPE family protein [Mycobacterium tuberculosis H37Rv]
 gi|38684069|emb|CAE55432.1| PPE FAMILY PROTEIN [Mycobacterium tuberculosis H37Rv]
Length=399

 Score =  194 bits (492),  Expect = 3e-47, Method: Compositional matrix adjust.
 Identities = 197/423 (47%), Positives = 252/423 (60%), Gaps = 35/423 (8%)

Query  2    LDFAQLPPEVNSALMYAGPGSGPMLAAAAAWEALAAELQTTASTYDALITGLADGPWQGS  61
            LDFA LPPE+NSA MY+G GS PMLAAA+AW  L+AEL+ +A +Y ++++ L    W G 
Sbjct  1    LDFATLPPEINSARMYSGAGSAPMLAAASAWHGLSAELRASALSYSSVLSTLTGEEWHGP  60

Query  62   SAASMVAAATPQVAWLRSTAGQAEQAGSQAVAAASAYEAAFFATVPPPEIAANRALLMAL  121
            ++ASM AAA P VAW+  TA +AEQAG+QA AAA+AYEAAF ATVPPP I ANRA LMAL
Sbjct  61   ASASMTAAAAPYVAWMSVTAVRAEQAGAQAEAAAAAYEAAFAATVPPPVIEANRAQLMAL  120

Query  122  LATNFLGQNTAAIAATEAQYAEMWAQDAAAMYGYAGASAAATQLSPFNPAAQTINPAGLA  181
            +ATN LGQN  AIAATEAQYAEMW+QDA AMYGYAGASAAATQL+PF    QT N +GLA
Sbjct  121  IATNVLGQNAPAIAATEAQYAEMWSQDAMAMYGYAGASAAATQLTPFTEPVQTTNASGLA  180

Query  182  SQAASVGQAVSGAANAQALTDIPKALFGLSGIFTNEPPWLTDLGKALGLTGHTWSSDGSG  241
            +Q+A++  A   +A AQ  T        LS +    P  L  L  +   T  T++S  SG
Sbjct  181  AQSAAIAHATGASAGAQQTT--------LSQLIAAIPSVLQGLSSS---TAATFASGPSG  229

Query  242  LIVGGVLGDFVQGVTGSAELDASVAM----DTFGKWVSPARLMV--TQFKDYFGLAHDLP  295
            L+  G++G      +GS+ LD   A+      F   ++ + L +       + GL   + 
Sbjct  230  LL--GIVG------SGSSWLDKLWALLDPNSNFWNTIASSGLFLPSNTIAPFLGLLGGVA  281

Query  296  KWASE----GAKAAGEAAKALPAAVPAIPSAGLSG-VAGAVGQAASVGGLKVPAVWTATT  350
               +     G   +G    AL A  P   + GL G VA  +G AA+VG L VP  WTA  
Sbjct  282  AADAAGDVLGEATSGGLGGALVA--PLGSAGGLGGTVAAGLGNAATVGTLSVPPSWTAAA  339

Query  351  PAASPAVLAASNGLGAAAAAEGSTHAFGGMPLMGSGAGRAFNNFAAPRYGFKPTVIAQPP  410
            P ASP + +A  G    A          GMP  G+  G+ F   A P+YGF+P  +A+PP
Sbjct  340  PLASP-LGSALGGTPMVAPPPAVAAGMPGMPF-GTMGGQGFGR-AVPQYGFRPNFVARPP  396

Query  411  AGG  413
            A G
Sbjct  397  AAG  399


>gi|148661613|ref|YP_001283136.1| PPE family protein [Mycobacterium tuberculosis H37Ra]
 gi|167967398|ref|ZP_02549675.1| PPE family protein [Mycobacterium tuberculosis H37Ra]
 gi|307084422|ref|ZP_07493535.1| PPE family protein [Mycobacterium tuberculosis SUMu012]
 gi|7478807|pir||H70931 probable PPE protein - Mycobacterium tuberculosis (strain H37RV)
 gi|148505765|gb|ABQ73574.1| PPE family protein [Mycobacterium tuberculosis H37Ra]
 gi|308365982|gb|EFP54833.1| PPE family protein [Mycobacterium tuberculosis SUMu012]
Length=403

 Score =  193 bits (491),  Expect = 4e-47, Method: Compositional matrix adjust.
 Identities = 197/423 (47%), Positives = 252/423 (60%), Gaps = 35/423 (8%)

Query  2    LDFAQLPPEVNSALMYAGPGSGPMLAAAAAWEALAAELQTTASTYDALITGLADGPWQGS  61
            LDFA LPPE+NSA MY+G GS PMLAAA+AW  L+AEL+ +A +Y ++++ L    W G 
Sbjct  5    LDFATLPPEINSARMYSGAGSAPMLAAASAWHGLSAELRASALSYSSVLSTLTGEEWHGP  64

Query  62   SAASMVAAATPQVAWLRSTAGQAEQAGSQAVAAASAYEAAFFATVPPPEIAANRALLMAL  121
            ++ASM AAA P VAW+  TA +AEQAG+QA AAA+AYEAAF ATVPPP I ANRA LMAL
Sbjct  65   ASASMTAAAAPYVAWMSVTAVRAEQAGAQAEAAAAAYEAAFAATVPPPVIEANRAQLMAL  124

Query  122  LATNFLGQNTAAIAATEAQYAEMWAQDAAAMYGYAGASAAATQLSPFNPAAQTINPAGLA  181
            +ATN LGQN  AIAATEAQYAEMW+QDA AMYGYAGASAAATQL+PF    QT N +GLA
Sbjct  125  IATNVLGQNAPAIAATEAQYAEMWSQDAMAMYGYAGASAAATQLTPFTEPVQTTNASGLA  184

Query  182  SQAASVGQAVSGAANAQALTDIPKALFGLSGIFTNEPPWLTDLGKALGLTGHTWSSDGSG  241
            +Q+A++  A   +A AQ  T        LS +    P  L  L  +   T  T++S  SG
Sbjct  185  AQSAAIAHATGASAGAQQTT--------LSQLIAAIPSVLQGLSSS---TAATFASGPSG  233

Query  242  LIVGGVLGDFVQGVTGSAELDASVAM----DTFGKWVSPARLMV--TQFKDYFGLAHDLP  295
            L+  G++G      +GS+ LD   A+      F   ++ + L +       + GL   + 
Sbjct  234  LL--GIVG------SGSSWLDKLWALLDPNSNFWNTIASSGLFLPSNTIAPFLGLLGGVA  285

Query  296  KWASE----GAKAAGEAAKALPAAVPAIPSAGLSG-VAGAVGQAASVGGLKVPAVWTATT  350
               +     G   +G    AL A  P   + GL G VA  +G AA+VG L VP  WTA  
Sbjct  286  AADAAGDVLGEATSGGLGGALVA--PLGSAGGLGGTVAAGLGNAATVGTLSVPPSWTAAA  343

Query  351  PAASPAVLAASNGLGAAAAAEGSTHAFGGMPLMGSGAGRAFNNFAAPRYGFKPTVIAQPP  410
            P ASP + +A  G    A          GMP  G+  G+ F   A P+YGF+P  +A+PP
Sbjct  344  PLASP-LGSALGGTPMVAPPPAVAAGMPGMPF-GTMGGQGFGR-AVPQYGFRPNFVARPP  400

Query  411  AGG  413
            A G
Sbjct  401  AAG  403


>gi|336457435|gb|EGO36444.1| PPE-repeat containing protein [Mycobacterium avium subsp. paratuberculosis 
S397]
Length=461

 Score =  193 bits (491),  Expect = 4e-47, Method: Compositional matrix adjust.
 Identities = 123/203 (61%), Positives = 144/203 (71%), Gaps = 0/203 (0%)

Query  2    LDFAQLPPEVNSALMYAGPGSGPMLAAAAAWEALAAELQTTASTYDALITGLADGPWQGS  61
            +DFA LPPEVNSA MYAGPGSGPMLAAA AW+ LAA L +TA +Y A IT L  GPW G 
Sbjct  1    MDFAVLPPEVNSARMYAGPGSGPMLAAAMAWDELAATLHSTADSYQAEITALTSGPWVGP  60

Query  62   SAASMVAAATPQVAWLRSTAGQAEQAGSQAVAAASAYEAAFFATVPPPEIAANRALLMAL  121
            SAA+M+AA TP + W+R+T  QAE+  + A AAA AYE AF  TVPPP + ANR LL  L
Sbjct  61   SAAAMIAAITPYLTWMRTTGAQAEETANNARAAAFAYETAFAETVPPPVVTANRTLLAQL  120

Query  122  LATNFLGQNTAAIAATEAQYAEMWAQDAAAMYGYAGASAAATQLSPFNPAAQTINPAGLA  181
            +ATN LGQNT AIA TEA+YAEMWA+DAAAMYGYAGA+AAAT+L+PF     T N     
Sbjct  121  VATNILGQNTPAIATTEAEYAEMWARDAAAMYGYAGAAAAATRLTPFTQPDPTTNSGADQ  180

Query  182  SQAASVGQAVSGAANAQALTDIP  204
            SQA S   A +  +    +T  P
Sbjct  181  SQAVSKAAATAAGSTRNTVTQQP  203


>gi|254821012|ref|ZP_05226013.1| PPE family protein, PPE31 [Mycobacterium intracellulare ATCC 
13950]
 gi|212596828|gb|ACJ35609.1| PPE48 [Mycobacterium intracellulare ATCC 13950]
Length=389

 Score =  189 bits (481),  Expect = 6e-46, Method: Compositional matrix adjust.
 Identities = 190/429 (45%), Positives = 240/429 (56%), Gaps = 57/429 (13%)

Query  1    MLDFAQLPPEVNSALMYAGPGSGPMLAAAAAWEALAAELQTTASTYDALITGLADGPWQG  60
             +DFA LPPE+NSA MYAGPGSGPML AA+AW  LAAEL++ A +Y + ++ L    W G
Sbjct  2    FVDFATLPPEINSARMYAGPGSGPMLVAASAWNGLAAELRSAALSYGSALSSLTSEEWHG  61

Query  61   SSAASMVAAATPQVAWLRSTAGQAEQAGSQAVAAASAYEAAFFATVPPPEIAANRALLMA  120
             ++A+MVAAATP VAW+ +TA QAEQA +QA AAA+AYEAAF ATVPPP IAANRA L  
Sbjct  62   PASAAMVAAATPYVAWMSTTATQAEQAATQAEAAAAAYEAAFAATVPPPAIAANRAQLAT  121

Query  121  LLATNFLGQNTAAIAATEAQYAEMWAQDAAAMYGYAGASAAATQLSPFNPAAQTINPAGL  180
            L+ATN LGQNT AIAATEAQY EMWAQDAA MYGYAG+SAAAT+L  F    QT +  G 
Sbjct  122  LIATNVLGQNTPAIAATEAQYGEMWAQDAATMYGYAGSSAAATRLPMFTDPTQTTSQDGQ  181

Query  181  ASQAASVGQAV-SGAANAQAL-----TDIPKALFGLSGIFTNEPPWLTDLGKALGLTGHT  234
            A QAA+V QA  + A N QA      T +P AL  LS    +     + L   L    + 
Sbjct  182  ARQAAAVAQATGTSAGNQQATVSQLNTAVPNALQTLSSPTESSTGSTSGLSSILDPNSNF  241

Query  235  WSSDGSGLIVGGVLGDFVQGVTGSAELDASVAMDTFGKWVSPARLMVTQFKDYFGLAHDL  294
            W++                 +T +  LD +  + T    V+ + L+         LA   
Sbjct  242  WNT-----------------ITSTGALDPAQVVQT----VTSSTLIGASTSALNDLASGA  280

Query  295  PKWASEGAKAAGEAAKALPAAVPAIPSAGLSGVAGA-------VGQAASVGGLKVPAVWT  347
            P      A   G +A++L         +GL+GV  A       +G+A+ VG L VP  W 
Sbjct  281  PV-----ATGIGTSAQSL---------SGLAGVGNAGASVSAGLGRASLVGPLSVPPSWA  326

Query  348  ATTPAASPAVLAASNGLGAAAAAEGSTHAFGGMPL--MGS-GAGRAFNNFAAPRYGFKPT  404
               P ASP + +A  G    A          GMP   MG+ G GRA      P+YGF+P 
Sbjct  327  PPAPVASP-LPSALGGTPMVAPPPAMAAGMPGMPFSPMGNHGLGRAV-----PQYGFRPN  380

Query  405  VIAQPPAGG  413
             + +PPA G
Sbjct  381  FVVRPPAAG  389


>gi|342861296|ref|ZP_08717944.1| PPE family protein [Mycobacterium colombiense CECT 3035]
 gi|342131196|gb|EGT84477.1| PPE family protein [Mycobacterium colombiense CECT 3035]
Length=395

 Score =  189 bits (479),  Expect = 9e-46, Method: Compositional matrix adjust.
 Identities = 116/189 (62%), Positives = 139/189 (74%), Gaps = 0/189 (0%)

Query  1    MLDFAQLPPEVNSALMYAGPGSGPMLAAAAAWEALAAELQTTASTYDALITGLADGPWQG  60
            MLDFA LPPE+NSA MY+GPGSGPMLAAAAAW  +AAE++  A++Y +++T L+   W G
Sbjct  1    MLDFAALPPEINSARMYSGPGSGPMLAAAAAWNTMAAEMRAAAASYGSVVTELSSEGWLG  60

Query  61   SSAASMVAAATPQVAWLRSTAGQAEQAGSQAVAAASAYEAAFFATVPPPEIAANRALLMA  120
             S+ SM+AAA P +AWL  TA QAE+ GSQA AAA+AYE+AF  TVPP  +AANRA L  
Sbjct  61   PSSMSMLAAAAPYLAWLDGTATQAEEVGSQAFAAATAYESAFAMTVPPAVVAANRAQLAM  120

Query  121  LLATNFLGQNTAAIAATEAQYAEMWAQDAAAMYGYAGASAAATQLSPFNPAAQTINPAGL  180
            L+ATN  GQNT AIAATEAQYAEMWAQDA AM GYA AS+AA Q +P        N  G+
Sbjct  121  LVATNIFGQNTPAIAATEAQYAEMWAQDAGAMNGYATASSAAAQFTPLATPQSNTNADGV  180

Query  181  ASQAASVGQ  189
            A Q  +V Q
Sbjct  181  AGQTNAVAQ  189


>gi|340627882|ref|YP_004746334.1| PPE family protein [Mycobacterium canettii CIPT 140010059]
 gi|340006072|emb|CCC45244.1| PPE family protein [Mycobacterium canettii CIPT 140010059]
Length=408

 Score =  188 bits (478),  Expect = 1e-45, Method: Compositional matrix adjust.
 Identities = 182/430 (43%), Positives = 231/430 (54%), Gaps = 40/430 (9%)

Query  2    LDFAQLPPEVNSALMYAGPGSGPMLAAAAAWEALAAELQTTASTYDALITGLADGPWQGS  61
            +DF  LPPE+NS  MYAGPGSGPM+AAAAAW++LAAEL   A  Y   I+ L    W G 
Sbjct  1    MDFGVLPPEINSGRMYAGPGSGPMMAAAAAWDSLAAELGLAAGGYRLAISELTGAYWVGP  60

Query  62   SAASMVAAATPQVAWLRSTAGQAEQAGSQAVAAASAYEAAFFATVPPPEIAANRALLMAL  121
            +AASMVAA TP VAWL +TAGQAEQAG QA AAA+AYE AF  TVPPP + ANRALL+AL
Sbjct  61   AAASMVAAVTPYVAWLSATAGQAEQAGMQARAAAAAYELAFAMTVPPPVVVANRALLVAL  120

Query  122  LATNFLGQNTAAIAATEAQYAEMWAQDAAAMYGYAGASAAATQLSPFNPAAQTINP-AGL  180
            +ATNF GQNT AIAATEAQYAEMWAQDAAAMY YAG++A AT+L+PF PA  T +P A  
Sbjct  121  VATNFFGQNTPAIAATEAQYAEMWAQDAAAMYTYAGSAAIATELTPFTPAPVTTSPAALA  180

Query  181  ASQAASVGQAVSGAANAQALTDIPKALFGLSGIFTNEPPWLTDLGK-----ALGLT----  231
               AA+V   V   A   A   +P+ L  LS   T+  PW + L +      LGLT    
Sbjct  181  GQAAATVSSTVPPVATTAA---VPQLLQQLSS--TSLIPWYSALQQWLAENLLGLTPDNR  235

Query  232  -------GHTWSSDGSGLIVGGVLGDFVQGVTGSAELDASVAMDTFGKWVSPARLMVTQF  284
                   G ++  +G       +    + G  G A    S  +D++G  +          
Sbjct  236  MTIVRLLGISYFDEGLLQFEASLAQQAIPGTPGGAGDSGSSVLDSWGPTI----------  285

Query  285  KDYFGLAHDLPKWASEGAKAAGEAAKALPAAVPAIPSAGLSG-VAGAVGQAASVGGLKVP  343
               F      P  A  GA    +  +  P    A+    + G V+ A+G+ +S G L VP
Sbjct  286  ---FAGPRASPSVAGGGAVGGVQTPQ--PYWYWALDRESIGGSVSAALGKGSSAGSLSVP  340

Query  344  AVWTATTPAASPAVLAASNGLGAAAAAEGSTHAFGGMPLMGSGAGRAFNNFAAPRYGFKP  403
              W A    A+PA          A           G P+  + AG++       +YGF+ 
Sbjct  341  PDWAARARWANPAAWRLPGDDVTALRGTAENALLRGFPM--ASAGQSTGGGFVHKYGFRL  398

Query  404  TVIAQPPAGG  413
             V+ +PP  G
Sbjct  399  AVMQRPPFAG  408


>gi|289447421|ref|ZP_06437165.1| PPE family protein [Mycobacterium tuberculosis CPHL_A]
 gi|289420379|gb|EFD17580.1| PPE family protein [Mycobacterium tuberculosis CPHL_A]
Length=403

 Score =  187 bits (474),  Expect = 3e-45, Method: Compositional matrix adjust.
 Identities = 198/423 (47%), Positives = 251/423 (60%), Gaps = 35/423 (8%)

Query  2    LDFAQLPPEVNSALMYAGPGSGPMLAAAAAWEALAAELQTTASTYDALITGLADGPWQGS  61
            LDFA LPPE+NSA MY+G GS PMLAAA+AW  L+AEL+ +A +Y ++++ L    W G 
Sbjct  5    LDFATLPPEINSARMYSGAGSAPMLAAASAWHGLSAELRASALSYSSVLSTLTGEEWHGP  64

Query  62   SAASMVAAATPQVAWLRSTAGQAEQAGSQAVAAASAYEAAFFATVPPPEIAANRALLMAL  121
            ++ASM AAA P VAW+  TA +AEQAG+QA AAA+AYEAAF ATVPPP I ANRA LMAL
Sbjct  65   ASASMTAAAAPYVAWMSVTAVRAEQAGAQAEAAAAAYEAAFAATVPPPVIEANRAQLMAL  124

Query  122  LATNFLGQNTAAIAATEAQYAEMWAQDAAAMYGYAGASAAATQLSPFNPAAQTINPAGLA  181
            +ATN LGQN  AIAATEAQYAEMW+QDA AMYGYAGASAAATQL+PF    QT N +GLA
Sbjct  125  IATNVLGQNAPAIAATEAQYAEMWSQDAMAMYGYAGASAAATQLTPFTEPVQTTNASGLA  184

Query  182  SQAASVGQAVSGAANAQALTDIPKALFGLSGIFTNEPPWLTDLGKALGLTGHTWSSDGSG  241
            +Q+A++  A   +A AQ  T        LS +    P  L  L  +   T  T +S  SG
Sbjct  185  AQSAAIAYATGASAGAQQTT--------LSQLIAAIPSVLQGLSSS---TAATSASGPSG  233

Query  242  LIVGGVLGDFVQGVTGSAELDASVAM----DTFGKWVSPARLMV--TQFKDYFGLAHDLP  295
            L+  G+LG      +GS+ LD   A+      F   ++ + L +       + GL   + 
Sbjct  234  LL--GILG------SGSSWLDKLWALLDPNSNFWNTIASSGLFLPSNTIAPFLGLLGGVA  285

Query  296  KWASE----GAKAAGEAAKALPAAVPAIPSAGLSG-VAGAVGQAASVGGLKVPAVWTATT  350
               +     G   +G    AL A  P   + GL G VA  +G AA+VG L VP  WTA  
Sbjct  286  AADAAGDVLGEATSGGLGGALVA--PLGSAGGLGGTVAAGLGNAATVGTLSVPPSWTAAA  343

Query  351  PAASPAVLAASNGLGAAAAAEGSTHAFGGMPLMGSGAGRAFNNFAAPRYGFKPTVIAQPP  410
            P ASP + +A  G    A          GMP  G+  G+ F   A P+YGF+P  +A+PP
Sbjct  344  PLASP-LGSALGGTPMVAPPPAVAAGMPGMPF-GTMGGQGFGR-AVPQYGFRPNFVARPP  400

Query  411  AGG  413
            A G
Sbjct  401  AAG  403


>gi|289761957|ref|ZP_06521335.1| predicted protein [Mycobacterium tuberculosis GM 1503]
 gi|289709463|gb|EFD73479.1| predicted protein [Mycobacterium tuberculosis GM 1503]
Length=403

 Score =  187 bits (474),  Expect = 3e-45, Method: Compositional matrix adjust.
 Identities = 197/423 (47%), Positives = 250/423 (60%), Gaps = 35/423 (8%)

Query  2    LDFAQLPPEVNSALMYAGPGSGPMLAAAAAWEALAAELQTTASTYDALITGLADGPWQGS  61
            LDFA LPPE+NSA MY+G GS PMLAAA+AW  L+AEL+ +A +Y ++++ L    W G 
Sbjct  5    LDFATLPPEINSARMYSGAGSAPMLAAASAWHGLSAELRASALSYSSVLSTLTGEEWHGP  64

Query  62   SAASMVAAATPQVAWLRSTAGQAEQAGSQAVAAASAYEAAFFATVPPPEIAANRALLMAL  121
            ++ASM AAA P VAW+  TA +AEQAG+QA  AA+AYEAAF ATVPPP I ANRA LMAL
Sbjct  65   ASASMTAAAAPYVAWMSVTAVRAEQAGAQAEGAAAAYEAAFAATVPPPVIEANRAQLMAL  124

Query  122  LATNFLGQNTAAIAATEAQYAEMWAQDAAAMYGYAGASAAATQLSPFNPAAQTINPAGLA  181
            +ATN LGQN  AIAATEAQYAEMW+QDA AMYGYAGASAAATQL+PF    QT N +GLA
Sbjct  125  IATNVLGQNAPAIAATEAQYAEMWSQDAMAMYGYAGASAAATQLTPFTEPVQTTNASGLA  184

Query  182  SQAASVGQAVSGAANAQALTDIPKALFGLSGIFTNEPPWLTDLGKALGLTGHTWSSDGSG  241
            +Q+A++  A   +A AQ  T        LS +    P  L  L  +   T  T +S  SG
Sbjct  185  AQSAAIAHATGASAGAQQTT--------LSQLIAAIPSVLQGLSSS---TAATSASGPSG  233

Query  242  LIVGGVLGDFVQGVTGSAELDASVAM----DTFGKWVSPARLMV--TQFKDYFGLAHDLP  295
            L+  G+LG      +GS+ LD   A+      F   ++ + L +       + GL   + 
Sbjct  234  LL--GILG------SGSSWLDKLWALLDPNSNFWNTIASSGLFLPSNTIAPFLGLLGGVA  285

Query  296  KWASE----GAKAAGEAAKALPAAVPAIPSAGLSG-VAGAVGQAASVGGLKVPAVWTATT  350
               +     G   +G    AL A  P   + GL G VA  +G AA+VG L VP  WTA  
Sbjct  286  AADAAGDVLGEATSGGLGGALVA--PLGSAGGLGGTVAAGLGNAATVGTLSVPPSWTAAA  343

Query  351  PAASPAVLAASNGLGAAAAAEGSTHAFGGMPLMGSGAGRAFNNFAAPRYGFKPTVIAQPP  410
            P ASP + +A  G    A          GMP  G+  G+ F   A P+YGF+P  +A+PP
Sbjct  344  PLASP-LGSALGGTPMVAPPPAVAAGMPGMPF-GTMGGQGFGR-AVPQYGFRPNFVARPP  400

Query  411  AGG  413
            A G
Sbjct  401  AAG  403


>gi|15841277|ref|NP_336314.1| PPE family protein [Mycobacterium tuberculosis CDC1551]
 gi|148823020|ref|YP_001287774.1| PPE family protein [Mycobacterium tuberculosis F11]
 gi|224990193|ref|YP_002644880.1| PPE family protein [Mycobacterium bovis BCG str. Tokyo 172]
 49 more sequence titles
 Length=403

 Score =  187 bits (474),  Expect = 3e-45, Method: Compositional matrix adjust.
 Identities = 198/423 (47%), Positives = 251/423 (60%), Gaps = 35/423 (8%)

Query  2    LDFAQLPPEVNSALMYAGPGSGPMLAAAAAWEALAAELQTTASTYDALITGLADGPWQGS  61
            LDFA LPPE+NSA MY+G GS PMLAAA+AW  L+AEL+ +A +Y ++++ L    W G 
Sbjct  5    LDFATLPPEINSARMYSGAGSAPMLAAASAWHGLSAELRASALSYSSVLSTLTGEEWHGP  64

Query  62   SAASMVAAATPQVAWLRSTAGQAEQAGSQAVAAASAYEAAFFATVPPPEIAANRALLMAL  121
            ++ASM AAA P VAW+  TA +AEQAG+QA AAA+AYEAAF ATVPPP I ANRA LMAL
Sbjct  65   ASASMTAAAAPYVAWMSVTAVRAEQAGAQAEAAAAAYEAAFAATVPPPVIEANRAQLMAL  124

Query  122  LATNFLGQNTAAIAATEAQYAEMWAQDAAAMYGYAGASAAATQLSPFNPAAQTINPAGLA  181
            +ATN LGQN  AIAATEAQYAEMW+QDA AMYGYAGASAAATQL+PF    QT N +GLA
Sbjct  125  IATNVLGQNAPAIAATEAQYAEMWSQDAMAMYGYAGASAAATQLTPFTEPVQTTNASGLA  184

Query  182  SQAASVGQAVSGAANAQALTDIPKALFGLSGIFTNEPPWLTDLGKALGLTGHTWSSDGSG  241
            +Q+A++  A   +A AQ  T        LS +    P  L  L  +   T  T +S  SG
Sbjct  185  AQSAAIAHATGASAGAQQTT--------LSQLIAAIPSVLQGLSSS---TAATSASGPSG  233

Query  242  LIVGGVLGDFVQGVTGSAELDASVAM----DTFGKWVSPARLMV--TQFKDYFGLAHDLP  295
            L+  G+LG      +GS+ LD   A+      F   ++ + L +       + GL   + 
Sbjct  234  LL--GILG------SGSSWLDKLWALLDPNSNFWNTIASSGLFLPSNTIAPFLGLLGGVA  285

Query  296  KWASE----GAKAAGEAAKALPAAVPAIPSAGLSG-VAGAVGQAASVGGLKVPAVWTATT  350
               +     G   +G    AL A  P   + GL G VA  +G AA+VG L VP  WTA  
Sbjct  286  AADAAGDVLGEATSGGLGGALVA--PLGSAGGLGGTVAAGLGNAATVGTLSVPPSWTAAA  343

Query  351  PAASPAVLAASNGLGAAAAAEGSTHAFGGMPLMGSGAGRAFNNFAAPRYGFKPTVIAQPP  410
            P ASP + +A  G    A          GMP  G+  G+ F   A P+YGF+P  +A+PP
Sbjct  344  PLASP-LGSALGGTPMVAPPPAVAAGMPGMPF-GTMGGQGFGR-AVPQYGFRPNFVARPP  400

Query  411  AGG  413
            A G
Sbjct  401  AAG  403


>gi|118618458|ref|YP_906790.1| PPE family protein [Mycobacterium ulcerans Agy99]
 gi|118570568|gb|ABL05319.1| PPE family protein [Mycobacterium ulcerans Agy99]
Length=386

 Score =  187 bits (474),  Expect = 4e-45, Method: Compositional matrix adjust.
 Identities = 131/245 (54%), Positives = 161/245 (66%), Gaps = 6/245 (2%)

Query  2    LDFAQLPPEVNSALMYAGPGSGPMLAAAAAWEALAAELQTTASTYDALITGLADGPWQGS  61
            LDFA LPPE+NSA MY+GPGS PMLAAA+AW+ LAAEL+ T  +YD+++  L    W G 
Sbjct  5    LDFATLPPEINSARMYSGPGSAPMLAAASAWKGLAAELRVTVLSYDSVLRALTGEEWYGP  64

Query  62   SAASMVAAATPQVAWLRSTAGQAEQAGSQAVAAASAYEAAFFATVPPPEIAANRALLMAL  121
            ++ASM AAA P VAW+ +TA QAE++  QA AAA+AYEAAF ATV P  I ANRA LM L
Sbjct  65   ASASMAAAAAPYVAWMSTTAAQAEESAVQAAAAAAAYEAAFSATVAPTVITANRAQLMVL  124

Query  122  LATNFLGQNTAAIAATEAQYAEMWAQDAAAMYGYAGASAAATQLSPFNPAAQTINPAGLA  181
            +ATN LGQNT  IAA EAQY EMWAQDA AMYGYAG+SAAAT+LS F       NPAGL 
Sbjct  125  VATNVLGQNTPTIAAVEAQYCEMWAQDAMAMYGYAGSSAAATRLSEFLAPQHNTNPAGLL  184

Query  182  SQAASVGQAVSGAANA-QALTDIPKALFGLSGIFT-----NEPPWLTDLGKALGLTGHTW  235
            +Q +++ Q +S   N  Q L     +    SG+ +     N   WL  L    G   + W
Sbjct  185  AQQSTLAQLMSAVPNVLQGLASSNTSASAPSGLLSTLLSGNGQSWLATLWSEFGPNANIW  244

Query  236  SSDGS  240
            ++  S
Sbjct  245  NTIAS  249


>gi|326903411|gb|EGE50344.1| LOW QUALITY PROTEIN: PPE family protein [Mycobacterium tuberculosis 
W-148]
Length=399

 Score =  187 bits (474),  Expect = 4e-45, Method: Compositional matrix adjust.
 Identities = 198/423 (47%), Positives = 251/423 (60%), Gaps = 35/423 (8%)

Query  2    LDFAQLPPEVNSALMYAGPGSGPMLAAAAAWEALAAELQTTASTYDALITGLADGPWQGS  61
            LDFA LPPE+NSA MY+G GS PMLAAA+AW  L+AEL+ +A +Y ++++ L    W G 
Sbjct  1    LDFATLPPEINSARMYSGAGSAPMLAAASAWHGLSAELRASALSYSSVLSTLTGEEWHGP  60

Query  62   SAASMVAAATPQVAWLRSTAGQAEQAGSQAVAAASAYEAAFFATVPPPEIAANRALLMAL  121
            ++ASM AAA P VAW+  TA +AEQAG+QA AAA+AYEAAF ATVPPP I ANRA LMAL
Sbjct  61   ASASMTAAAAPYVAWMSVTAVRAEQAGAQAEAAAAAYEAAFAATVPPPVIEANRAQLMAL  120

Query  122  LATNFLGQNTAAIAATEAQYAEMWAQDAAAMYGYAGASAAATQLSPFNPAAQTINPAGLA  181
            +ATN LGQN  AIAATEAQYAEMW+QDA AMYGYAGASAAATQL+PF    QT N +GLA
Sbjct  121  IATNVLGQNAPAIAATEAQYAEMWSQDAMAMYGYAGASAAATQLTPFTEPVQTTNASGLA  180

Query  182  SQAASVGQAVSGAANAQALTDIPKALFGLSGIFTNEPPWLTDLGKALGLTGHTWSSDGSG  241
            +Q+A++  A   +A AQ  T        LS +    P  L  L  +   T  T +S  SG
Sbjct  181  AQSAAIAHATGASAGAQQTT--------LSQLIAAIPSVLQGLSSS---TAATSASGPSG  229

Query  242  LIVGGVLGDFVQGVTGSAELDASVAM----DTFGKWVSPARLMV--TQFKDYFGLAHDLP  295
            L+  G+LG      +GS+ LD   A+      F   ++ + L +       + GL   + 
Sbjct  230  LL--GILG------SGSSWLDKLWALLDPNSNFWNTIASSGLFLPSNTIAPFLGLLGGVA  281

Query  296  KWASE----GAKAAGEAAKALPAAVPAIPSAGLSG-VAGAVGQAASVGGLKVPAVWTATT  350
               +     G   +G    AL A  P   + GL G VA  +G AA+VG L VP  WTA  
Sbjct  282  AADAAGDVLGEATSGGLGGALVA--PLGSAGGLGGTVAAGLGNAATVGTLSVPPSWTAAA  339

Query  351  PAASPAVLAASNGLGAAAAAEGSTHAFGGMPLMGSGAGRAFNNFAAPRYGFKPTVIAQPP  410
            P ASP + +A  G    A          GMP  G+  G+ F   A P+YGF+P  +A+PP
Sbjct  340  PLASP-LGSALGGTPMVAPPPAVAAGMPGMPF-GTMGGQGFGR-AVPQYGFRPNFVARPP  396

Query  411  AGG  413
            A G
Sbjct  397  AAG  399


>gi|296164838|ref|ZP_06847396.1| PPE family protein [Mycobacterium parascrofulaceum ATCC BAA-614]
 gi|295899804|gb|EFG79252.1| PPE family protein [Mycobacterium parascrofulaceum ATCC BAA-614]
Length=453

 Score =  186 bits (471),  Expect = 8e-45, Method: Compositional matrix adjust.
 Identities = 167/392 (43%), Positives = 232/392 (60%), Gaps = 42/392 (10%)

Query  2    LDFAQLPPEVNSALMYAGPGSGPMLAAAAAWEALAAELQTTASTYDALITGLADGPWQGS  61
            +DFA LPPEVNSA MYAG G+G ++ AAAAWE LA EL + A++Y A+++ L  GPW+G+
Sbjct  3    VDFAALPPEVNSARMYAGAGAGSLVTAAAAWEKLATELSSAAASYRAIVSELTGGPWEGA  62

Query  62   SAASMVAAATPQVAWLRSTAGQAEQAGSQAVAAASAYEAAFFATVPPPEIAANRALLMAL  121
            S+ +M AA  P V+W+ +TA QA+Q  SQ  +AA+AYEAAF ATVPPPEI  NRALL +L
Sbjct  63   SSGTMAAAVAPYVSWMNTTAAQAQQTASQLGSAAAAYEAAFAATVPPPEIEVNRALLASL  122

Query  122  LATNFLGQNTAAIAATEAQYAEMWAQDAAAMYGYAGASAAATQLSPFNPAAQTINPAGLA  181
            ++TN LGQNT AIAATEAQY++MWAQDAAAMYGYAGASAAAT+L+PF    QT N +G  
Sbjct  123  VSTNVLGQNTPAIAATEAQYSQMWAQDAAAMYGYAGASAAATRLTPFAAPQQTTNQSGTT  182

Query  182  SQAASVGQAVS--GAANAQALTDIPKALFGLSGIFTNEPPWLTDLGKALGLTGHTWSSDG  239
            +Q ++V +A++  G+     L++IP  L   S                    G + ++ G
Sbjct  183  NQNSAVMKAMATGGSNTTSTLSNIPNMLKQSSA-------------------GSSGTTAG  223

Query  240  SGLIVGGVLGDFVQGVTGSAELDASVAMDTFGKWVSPARLMVTQFKDYFGLAHDLPKWAS  299
            SG  +  +  +F +   G   L   +  D  G  ++ A  +   +     L   L   AS
Sbjct  224  SGGSLVDLFNNFSENTIGYQILSEGLNFDASGALLTLAPPVAAAWNP---LVDSLSAPAS  280

Query  300  EGAKAAGEAAKALPAAVPAIPSAGLSGVAGAVGQAASVGGLKVPAVWTATTPAASPAVLA  359
              ++ +G  +  + ++ PA P     GV+  +G+AASVG L VP  W+     ASP +  
Sbjct  281  AASQVSGAGSALVNSSAPAAP-----GVSAGLGEAASVGKLSVPQSWS-----ASPGIRL  330

Query  360  ASNGLGAAAAAEGSTHA-------FGGMPLMG  384
            A+  L  +A  +G   A       +GGMP MG
Sbjct  331  AATAL-PSAGLDGLPQAGAVAPGFYGGMPPMG  361


>gi|31792996|ref|NP_855489.1| PPE family protein [Mycobacterium bovis AF2122/97]
 gi|121637709|ref|YP_977932.1| PPE family protein [Mycobacterium bovis BCG str. Pasteur 1173P2]
 gi|31618587|emb|CAD94539.1| PPE FAMILY PROTEIN [Mycobacterium bovis AF2122/97]
 gi|121493356|emb|CAL71827.1| PPE family protein [Mycobacterium bovis BCG str. Pasteur 1173P2]
Length=399

 Score =  186 bits (471),  Expect = 8e-45, Method: Compositional matrix adjust.
 Identities = 197/423 (47%), Positives = 251/423 (60%), Gaps = 35/423 (8%)

Query  2    LDFAQLPPEVNSALMYAGPGSGPMLAAAAAWEALAAELQTTASTYDALITGLADGPWQGS  61
            +DFA LPPE+NSA MY+G GS PMLAAA+AW  L+AEL+ +A +Y ++++ L    W G 
Sbjct  1    MDFATLPPEINSARMYSGAGSAPMLAAASAWHGLSAELRASALSYSSVLSTLTGEEWHGP  60

Query  62   SAASMVAAATPQVAWLRSTAGQAEQAGSQAVAAASAYEAAFFATVPPPEIAANRALLMAL  121
            ++ASM AAA P VAW+  TA +AEQAG+QA AAA+AYEAAF ATVPPP I ANRA LMAL
Sbjct  61   ASASMTAAAAPYVAWMSVTAVRAEQAGAQAEAAAAAYEAAFAATVPPPVIEANRAQLMAL  120

Query  122  LATNFLGQNTAAIAATEAQYAEMWAQDAAAMYGYAGASAAATQLSPFNPAAQTINPAGLA  181
            +ATN LGQN  AIAATEAQYAEMW+QDA AMYGYAGASAAATQL+PF    QT N +GLA
Sbjct  121  IATNVLGQNAPAIAATEAQYAEMWSQDAMAMYGYAGASAAATQLTPFTEPVQTTNASGLA  180

Query  182  SQAASVGQAVSGAANAQALTDIPKALFGLSGIFTNEPPWLTDLGKALGLTGHTWSSDGSG  241
            +Q+A++  A   +A AQ  T        LS +    P  L  L  +   T  T +S  SG
Sbjct  181  AQSAAIAHATGASAGAQQTT--------LSQLIAAIPSVLQGLSSS---TAATSASGPSG  229

Query  242  LIVGGVLGDFVQGVTGSAELDASVAM----DTFGKWVSPARLMV--TQFKDYFGLAHDLP  295
            L+  G+LG      +GS+ LD   A+      F   ++ + L +       + GL   + 
Sbjct  230  LL--GILG------SGSSWLDKLWALLDPNSNFWNTIASSGLFLPSNTIAPFLGLLGGVA  281

Query  296  KWASE----GAKAAGEAAKALPAAVPAIPSAGLSG-VAGAVGQAASVGGLKVPAVWTATT  350
               +     G   +G    AL A  P   + GL G VA  +G AA+VG L VP  WTA  
Sbjct  282  AADAAGDVLGEATSGGLGGALVA--PLGSAGGLGGTVAAGLGNAATVGTLSVPPSWTAAA  339

Query  351  PAASPAVLAASNGLGAAAAAEGSTHAFGGMPLMGSGAGRAFNNFAAPRYGFKPTVIAQPP  410
            P ASP + +A  G    A          GMP  G+  G+ F   A P+YGF+P  +A+PP
Sbjct  340  PLASP-LGSALGGTPMVAPPPAVAAGMPGMPF-GTMGGQGFGR-AVPQYGFRPNFVARPP  396

Query  411  AGG  413
            A G
Sbjct  397  AAG  399


>gi|341601736|emb|CCC64409.1| PPE family protein [Mycobacterium bovis BCG str. Moreau RDJ]
Length=403

 Score =  185 bits (470),  Expect = 1e-44, Method: Compositional matrix adjust.
 Identities = 197/423 (47%), Positives = 250/423 (60%), Gaps = 35/423 (8%)

Query  2    LDFAQLPPEVNSALMYAGPGSGPMLAAAAAWEALAAELQTTASTYDALITGLADGPWQGS  61
            LDF  LPPE+NSA MY+G GS PMLAAA+AW  L+AEL+ +A +Y ++++ L    W G 
Sbjct  5    LDFMTLPPEINSARMYSGAGSAPMLAAASAWHGLSAELRASALSYSSVLSTLTGEEWHGP  64

Query  62   SAASMVAAATPQVAWLRSTAGQAEQAGSQAVAAASAYEAAFFATVPPPEIAANRALLMAL  121
            ++ASM AAA P VAW+  TA +AEQAG+QA AAA+AYEAAF ATVPPP I ANRA LMAL
Sbjct  65   ASASMTAAAAPYVAWMSVTAVRAEQAGAQAEAAAAAYEAAFAATVPPPVIEANRAQLMAL  124

Query  122  LATNFLGQNTAAIAATEAQYAEMWAQDAAAMYGYAGASAAATQLSPFNPAAQTINPAGLA  181
            +ATN LGQN  AIAATEAQYAEMW+QDA AMYGYAGASAAATQL+PF    QT N +GLA
Sbjct  125  IATNVLGQNAPAIAATEAQYAEMWSQDAMAMYGYAGASAAATQLTPFTEPVQTTNASGLA  184

Query  182  SQAASVGQAVSGAANAQALTDIPKALFGLSGIFTNEPPWLTDLGKALGLTGHTWSSDGSG  241
            +Q+A++  A   +A AQ  T        LS +    P  L  L  +   T  T +S  SG
Sbjct  185  AQSAAIAHATGASAGAQQTT--------LSQLIAAIPSVLQGLSSS---TAATSASGPSG  233

Query  242  LIVGGVLGDFVQGVTGSAELDASVAM----DTFGKWVSPARLMV--TQFKDYFGLAHDLP  295
            L+  G+LG      +GS+ LD   A+      F   ++ + L +       + GL   + 
Sbjct  234  LL--GILG------SGSSWLDKLWALLDPNSNFWNTIASSGLFLPSNTIAPFLGLLGGVA  285

Query  296  KWASE----GAKAAGEAAKALPAAVPAIPSAGLSG-VAGAVGQAASVGGLKVPAVWTATT  350
               +     G   +G    AL A  P   + GL G VA  +G AA+VG L VP  WTA  
Sbjct  286  AADAAGDVLGEATSGGLGGALVA--PLGSAGGLGGTVAAGLGNAATVGTLSVPPSWTAAA  343

Query  351  PAASPAVLAASNGLGAAAAAEGSTHAFGGMPLMGSGAGRAFNNFAAPRYGFKPTVIAQPP  410
            P ASP + +A  G    A          GMP  G+  G+ F   A P+YGF+P  +A+PP
Sbjct  344  PLASP-LGSALGGTPMVAPPPAVAAGMPGMPF-GTMGGQGFGR-AVPQYGFRPNFVARPP  400

Query  411  AGG  413
            A G
Sbjct  401  AAG  403



Lambda     K      H
   0.313    0.126    0.371 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Effective search space used: 828519148872


  Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
    Posted date:  Sep 5, 2011  4:36 AM
  Number of letters in database: 5,219,829,388
  Number of sequences in database:  15,229,318



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40