BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv3645 Length=549 Score E Sequences producing significant alignments: (Bits) Value gi|15610781|ref|NP_218162.1| transmembrane protein [Mycobacteriu... 1081 0.0 gi|340628617|ref|YP_004747069.1| hypothetical protein MCAN_36651... 1080 0.0 gi|289572292|ref|ZP_06452519.1| transmembrane protein [Mycobacte... 1080 0.0 gi|289441075|ref|ZP_06430819.1| conserved membrane protein [Myco... 1078 0.0 gi|339633637|ref|YP_004725279.1| hypothetical protein MAF_36520 ... 1078 0.0 gi|167968567|ref|ZP_02550844.1| conserved transmembrane protein ... 974 0.0 gi|41406524|ref|NP_959360.1| hypothetical protein MAP0426c [Myco... 899 0.0 gi|289763822|ref|ZP_06523200.1| adenylate cyclase [Mycobacterium... 890 0.0 gi|118465478|ref|YP_879800.1| adenylate cyclase, family protein ... 883 0.0 gi|240173038|ref|ZP_04751696.1| putative transmembrane protein [... 881 0.0 gi|336460891|gb|EGO39775.1| family 3 adenylate cyclase [Mycobact... 880 0.0 gi|296166700|ref|ZP_06849125.1| adenylate cyclase, family protei... 880 0.0 gi|183985105|ref|YP_001853396.1| adenylate cyclase [Mycobacteriu... 880 0.0 gi|118619391|ref|YP_907723.1| adenylate cyclase [Mycobacterium u... 876 0.0 gi|15827006|ref|NP_301269.1| hypothetical protein ML0201 [Mycoba... 867 0.0 gi|342862018|ref|ZP_08718662.1| adenylate cyclase, family protei... 858 0.0 gi|254773488|ref|ZP_05215004.1| adenylate cyclase, family protei... 855 0.0 gi|254821837|ref|ZP_05226838.1| adenylate cyclase, family protei... 845 0.0 gi|145221987|ref|YP_001132665.1| putative adenylate/guanylate cy... 792 0.0 gi|118470462|ref|YP_890374.1| adenylate cyclase, family protein ... 792 0.0 gi|108801758|ref|YP_641955.1| adenylate/guanylate cyclase [Mycob... 790 0.0 gi|120406343|ref|YP_956172.1| putative adenylate/guanylate cycla... 783 0.0 gi|289748159|ref|ZP_06507537.1| transmembrane protein [Mycobacte... 782 0.0 gi|339296457|gb|AEJ48568.1| conserved transmembrane protein [Myc... 780 0.0 gi|333992570|ref|YP_004525184.1| adenylate cyclase [Mycobacteriu... 768 0.0 gi|169627594|ref|YP_001701243.1| putative adenylate cyclase [Myc... 661 0.0 gi|343926497|ref|ZP_08766002.1| putative adenylate cyclase [Gord... 509 6e-142 gi|326383463|ref|ZP_08205150.1| adenylyl cyclase class-3/4/guany... 490 2e-136 gi|262200590|ref|YP_003271798.1| adenylyl cyclase class-3/4/guan... 484 2e-134 gi|296141546|ref|YP_003648789.1| adenylate/guanylate cyclase wit... 475 8e-132 gi|319951223|ref|ZP_08025061.1| putative adenylate cyclase [Diet... 437 3e-120 gi|226304564|ref|YP_002764522.1| adenylate cyclase [Rhodococcus ... 402 9e-110 gi|226364628|ref|YP_002782410.1| adenylate cyclase [Rhodococcus ... 400 2e-109 gi|334564335|ref|ZP_08517326.1| adenylate cyclase [Corynebacteri... 396 4e-108 gi|38232953|ref|NP_938720.1| putative adenylate cyclase [Coryneb... 396 5e-108 gi|227505639|ref|ZP_03935688.1| adenylate cyclase [Corynebacteri... 395 9e-108 gi|296118103|ref|ZP_06836685.1| putative adenylate cyclase [Cory... 393 3e-107 gi|172041526|ref|YP_001801241.1| adenylate cyclase, putative [Co... 392 6e-107 gi|227549699|ref|ZP_03979748.1| adenylate cyclase [Corynebacteri... 389 5e-106 gi|229494635|ref|ZP_04388398.1| adenylate cyclase, family 3 [Rho... 389 7e-106 gi|296394982|ref|YP_003659866.1| adenylate/guanylate cyclase wit... 387 2e-105 gi|111022135|ref|YP_705107.1| adenylate cyclase [Rhodococcus jos... 387 2e-105 gi|300857644|ref|YP_003782627.1| adenylate cyclase [Corynebacter... 386 4e-105 gi|255324203|ref|ZP_05365325.1| adenylate cyclase, family 3 [Cor... 386 4e-105 gi|302205382|gb|ADL09724.1| Adenylate cyclase [Corynebacterium p... 386 4e-105 gi|337289888|ref|YP_004628909.1| adenylate cyclase [Corynebacter... 386 5e-105 gi|311741024|ref|ZP_07714849.1| probable adenylate cyclase [Cory... 386 6e-105 gi|259506071|ref|ZP_05748973.1| adenylate cyclase [Corynebacteri... 385 9e-105 gi|68537046|ref|YP_251751.1| adenylate cyclase, putative [Coryne... 385 9e-105 gi|25026866|ref|NP_736920.1| hypothetical protein CE0310 [Coryne... 385 1e-104 >gi|15610781|ref|NP_218162.1| transmembrane protein [Mycobacterium tuberculosis H37Rv] gi|15843257|ref|NP_338294.1| adenylate cyclase, putative [Mycobacterium tuberculosis CDC1551] gi|31794815|ref|NP_857308.1| transmembrane protein [Mycobacterium bovis AF2122/97] 61 more sequence titles Length=549 Score = 1081 bits (2796), Expect = 0.0, Method: Compositional matrix adjust. Identities = 549/549 (100%), Positives = 549/549 (100%), Gaps = 0/549 (0%) Query 1 MDAEAFVGFRQVPAARYGGLMATTAALPRRIHAFVRWVVRTPWPLFSLSMLQSDIIGALF 60 MDAEAFVGFRQVPAARYGGLMATTAALPRRIHAFVRWVVRTPWPLFSLSMLQSDIIGALF Sbjct 1 MDAEAFVGFRQVPAARYGGLMATTAALPRRIHAFVRWVVRTPWPLFSLSMLQSDIIGALF 60 Query 61 VLGFLRYGLPPQDNIQLQDLPPVNLLIFVSTVIILFLAGAVVNLKLLMPVFRWQRRDNLL 120 VLGFLRYGLPPQDNIQLQDLPPVNLLIFVSTVIILFLAGAVVNLKLLMPVFRWQRRDNLL Sbjct 61 VLGFLRYGLPPQDNIQLQDLPPVNLLIFVSTVIILFLAGAVVNLKLLMPVFRWQRRDNLL 120 Query 121 TEPDPAATELARSRALRMPLYRTLISLAVWATGGGVFILASWSVAKHAAPVVAVATALGA 180 TEPDPAATELARSRALRMPLYRTLISLAVWATGGGVFILASWSVAKHAAPVVAVATALGA Sbjct 121 TEPDPAATELARSRALRMPLYRTLISLAVWATGGGVFILASWSVAKHAAPVVAVATALGA 180 Query 181 TATAIIGYLQSERVLRPVAVAALRSGVPENVNAPGVILRLMLAWIPSTGVPLLAIVLAVA 240 TATAIIGYLQSERVLRPVAVAALRSGVPENVNAPGVILRLMLAWIPSTGVPLLAIVLAVA Sbjct 181 TATAIIGYLQSERVLRPVAVAALRSGVPENVNAPGVILRLMLAWIPSTGVPLLAIVLAVA 240 Query 241 ADKIALLHATPEALFNPILMMALAALGIGSVSTLLVAMSIADPLRQLRWALSEVQRGNYN 300 ADKIALLHATPEALFNPILMMALAALGIGSVSTLLVAMSIADPLRQLRWALSEVQRGNYN Sbjct 241 ADKIALLHATPEALFNPILMMALAALGIGSVSTLLVAMSIADPLRQLRWALSEVQRGNYN 300 Query 301 AHMQIYDASELGLLQAGFNDMVRELSERQRLRDLFGRYVGEDVARRALERGTELGGQERD 360 AHMQIYDASELGLLQAGFNDMVRELSERQRLRDLFGRYVGEDVARRALERGTELGGQERD Sbjct 301 AHMQIYDASELGLLQAGFNDMVRELSERQRLRDLFGRYVGEDVARRALERGTELGGQERD 360 Query 361 VAVLFVDLVGSTQLAATRPPAEVVQLLNEFFRVVVETVARHGGFVNKFQGDAALAIFGAP 420 VAVLFVDLVGSTQLAATRPPAEVVQLLNEFFRVVVETVARHGGFVNKFQGDAALAIFGAP Sbjct 361 VAVLFVDLVGSTQLAATRPPAEVVQLLNEFFRVVVETVARHGGFVNKFQGDAALAIFGAP 420 Query 421 IEHPDGAGAALSAARELHDELIPVLGSAEFGIGVSAGRAIAGHIGAQARFEYTVIGDPVN 480 IEHPDGAGAALSAARELHDELIPVLGSAEFGIGVSAGRAIAGHIGAQARFEYTVIGDPVN Sbjct 421 IEHPDGAGAALSAARELHDELIPVLGSAEFGIGVSAGRAIAGHIGAQARFEYTVIGDPVN 480 Query 481 EAARLTELAKLEDGHVLASAIAVSGALDAEALCWDVGEVVELRGRAAPTQLARPMNLAAP 540 EAARLTELAKLEDGHVLASAIAVSGALDAEALCWDVGEVVELRGRAAPTQLARPMNLAAP Sbjct 481 EAARLTELAKLEDGHVLASAIAVSGALDAEALCWDVGEVVELRGRAAPTQLARPMNLAAP 540 Query 541 EEVSSEVRG 549 EEVSSEVRG Sbjct 541 EEVSSEVRG 549 >gi|340628617|ref|YP_004747069.1| hypothetical protein MCAN_36651 [Mycobacterium canettii CIPT 140010059] gi|340006807|emb|CCC45996.1| putative conserved transmembrane protein [Mycobacterium canettii CIPT 140010059] Length=549 Score = 1080 bits (2792), Expect = 0.0, Method: Compositional matrix adjust. Identities = 548/548 (100%), Positives = 548/548 (100%), Gaps = 0/548 (0%) Query 1 MDAEAFVGFRQVPAARYGGLMATTAALPRRIHAFVRWVVRTPWPLFSLSMLQSDIIGALF 60 MDAEAFVGFRQVPAARYGGLMATTAALPRRIHAFVRWVVRTPWPLFSLSMLQSDIIGALF Sbjct 1 MDAEAFVGFRQVPAARYGGLMATTAALPRRIHAFVRWVVRTPWPLFSLSMLQSDIIGALF 60 Query 61 VLGFLRYGLPPQDNIQLQDLPPVNLLIFVSTVIILFLAGAVVNLKLLMPVFRWQRRDNLL 120 VLGFLRYGLPPQDNIQLQDLPPVNLLIFVSTVIILFLAGAVVNLKLLMPVFRWQRRDNLL Sbjct 61 VLGFLRYGLPPQDNIQLQDLPPVNLLIFVSTVIILFLAGAVVNLKLLMPVFRWQRRDNLL 120 Query 121 TEPDPAATELARSRALRMPLYRTLISLAVWATGGGVFILASWSVAKHAAPVVAVATALGA 180 TEPDPAATELARSRALRMPLYRTLISLAVWATGGGVFILASWSVAKHAAPVVAVATALGA Sbjct 121 TEPDPAATELARSRALRMPLYRTLISLAVWATGGGVFILASWSVAKHAAPVVAVATALGA 180 Query 181 TATAIIGYLQSERVLRPVAVAALRSGVPENVNAPGVILRLMLAWIPSTGVPLLAIVLAVA 240 TATAIIGYLQSERVLRPVAVAALRSGVPENVNAPGVILRLMLAWIPSTGVPLLAIVLAVA Sbjct 181 TATAIIGYLQSERVLRPVAVAALRSGVPENVNAPGVILRLMLAWIPSTGVPLLAIVLAVA 240 Query 241 ADKIALLHATPEALFNPILMMALAALGIGSVSTLLVAMSIADPLRQLRWALSEVQRGNYN 300 ADKIALLHATPEALFNPILMMALAALGIGSVSTLLVAMSIADPLRQLRWALSEVQRGNYN Sbjct 241 ADKIALLHATPEALFNPILMMALAALGIGSVSTLLVAMSIADPLRQLRWALSEVQRGNYN 300 Query 301 AHMQIYDASELGLLQAGFNDMVRELSERQRLRDLFGRYVGEDVARRALERGTELGGQERD 360 AHMQIYDASELGLLQAGFNDMVRELSERQRLRDLFGRYVGEDVARRALERGTELGGQERD Sbjct 301 AHMQIYDASELGLLQAGFNDMVRELSERQRLRDLFGRYVGEDVARRALERGTELGGQERD 360 Query 361 VAVLFVDLVGSTQLAATRPPAEVVQLLNEFFRVVVETVARHGGFVNKFQGDAALAIFGAP 420 VAVLFVDLVGSTQLAATRPPAEVVQLLNEFFRVVVETVARHGGFVNKFQGDAALAIFGAP Sbjct 361 VAVLFVDLVGSTQLAATRPPAEVVQLLNEFFRVVVETVARHGGFVNKFQGDAALAIFGAP 420 Query 421 IEHPDGAGAALSAARELHDELIPVLGSAEFGIGVSAGRAIAGHIGAQARFEYTVIGDPVN 480 IEHPDGAGAALSAARELHDELIPVLGSAEFGIGVSAGRAIAGHIGAQARFEYTVIGDPVN Sbjct 421 IEHPDGAGAALSAARELHDELIPVLGSAEFGIGVSAGRAIAGHIGAQARFEYTVIGDPVN 480 Query 481 EAARLTELAKLEDGHVLASAIAVSGALDAEALCWDVGEVVELRGRAAPTQLARPMNLAAP 540 EAARLTELAKLEDGHVLASAIAVSGALDAEALCWDVGEVVELRGRAAPTQLARPMNLAAP Sbjct 481 EAARLTELAKLEDGHVLASAIAVSGALDAEALCWDVGEVVELRGRAAPTQLARPMNLAAP 540 Query 541 EEVSSEVR 548 EEVSSEVR Sbjct 541 EEVSSEVR 548 >gi|289572292|ref|ZP_06452519.1| transmembrane protein [Mycobacterium tuberculosis K85] gi|289536723|gb|EFD41301.1| transmembrane protein [Mycobacterium tuberculosis K85] Length=549 Score = 1080 bits (2792), Expect = 0.0, Method: Compositional matrix adjust. Identities = 548/549 (99%), Positives = 548/549 (99%), Gaps = 0/549 (0%) Query 1 MDAEAFVGFRQVPAARYGGLMATTAALPRRIHAFVRWVVRTPWPLFSLSMLQSDIIGALF 60 MDAEAFVGFRQVPAARYGGLMATTAALPRRIHAFVRWVVRTPWPLFSLSMLQSDIIGALF Sbjct 1 MDAEAFVGFRQVPAARYGGLMATTAALPRRIHAFVRWVVRTPWPLFSLSMLQSDIIGALF 60 Query 61 VLGFLRYGLPPQDNIQLQDLPPVNLLIFVSTVIILFLAGAVVNLKLLMPVFRWQRRDNLL 120 VLGFLRYGLPPQDNIQLQDLPPVNLLIFVSTVIILFLAGAVVNLKLLMPVFRWQRRDNLL Sbjct 61 VLGFLRYGLPPQDNIQLQDLPPVNLLIFVSTVIILFLAGAVVNLKLLMPVFRWQRRDNLL 120 Query 121 TEPDPAATELARSRALRMPLYRTLISLAVWATGGGVFILASWSVAKHAAPVVAVATALGA 180 TEPDPAATELARSRALRMPLYRTLISLAVWATGGGVFILASWSVAKHAAPVVAVATALGA Sbjct 121 TEPDPAATELARSRALRMPLYRTLISLAVWATGGGVFILASWSVAKHAAPVVAVATALGA 180 Query 181 TATAIIGYLQSERVLRPVAVAALRSGVPENVNAPGVILRLMLAWIPSTGVPLLAIVLAVA 240 TATAIIGYLQSERVLRPVAVAALRSGVPENVNAPGVILRLMLAWIPSTGVPLLAIVLAVA Sbjct 181 TATAIIGYLQSERVLRPVAVAALRSGVPENVNAPGVILRLMLAWIPSTGVPLLAIVLAVA 240 Query 241 ADKIALLHATPEALFNPILMMALAALGIGSVSTLLVAMSIADPLRQLRWALSEVQRGNYN 300 ADKIALLHATPEALFNPILMMALAALGIGSVSTLLVAMSIADPLRQLRWALSEVQRGNYN Sbjct 241 ADKIALLHATPEALFNPILMMALAALGIGSVSTLLVAMSIADPLRQLRWALSEVQRGNYN 300 Query 301 AHMQIYDASELGLLQAGFNDMVRELSERQRLRDLFGRYVGEDVARRALERGTELGGQERD 360 AHMQIYDASELGLLQAGFNDMVRELSERQRLRDLFGRYVGEDVARRALERGTELGGQERD Sbjct 301 AHMQIYDASELGLLQAGFNDMVRELSERQRLRDLFGRYVGEDVARRALERGTELGGQERD 360 Query 361 VAVLFVDLVGSTQLAATRPPAEVVQLLNEFFRVVVETVARHGGFVNKFQGDAALAIFGAP 420 VAVLFVDLVGSTQLAATRPPAEVVQLLNEFFRVVVETVARH GFVNKFQGDAALAIFGAP Sbjct 361 VAVLFVDLVGSTQLAATRPPAEVVQLLNEFFRVVVETVARHSGFVNKFQGDAALAIFGAP 420 Query 421 IEHPDGAGAALSAARELHDELIPVLGSAEFGIGVSAGRAIAGHIGAQARFEYTVIGDPVN 480 IEHPDGAGAALSAARELHDELIPVLGSAEFGIGVSAGRAIAGHIGAQARFEYTVIGDPVN Sbjct 421 IEHPDGAGAALSAARELHDELIPVLGSAEFGIGVSAGRAIAGHIGAQARFEYTVIGDPVN 480 Query 481 EAARLTELAKLEDGHVLASAIAVSGALDAEALCWDVGEVVELRGRAAPTQLARPMNLAAP 540 EAARLTELAKLEDGHVLASAIAVSGALDAEALCWDVGEVVELRGRAAPTQLARPMNLAAP Sbjct 481 EAARLTELAKLEDGHVLASAIAVSGALDAEALCWDVGEVVELRGRAAPTQLARPMNLAAP 540 Query 541 EEVSSEVRG 549 EEVSSEVRG Sbjct 541 EEVSSEVRG 549 >gi|289441075|ref|ZP_06430819.1| conserved membrane protein [Mycobacterium tuberculosis T46] gi|289571882|ref|ZP_06452109.1| conserved membrane protein [Mycobacterium tuberculosis T17] gi|289755771|ref|ZP_06515149.1| transmembrane protein [Mycobacterium tuberculosis EAS054] gi|289413994|gb|EFD11234.1| conserved membrane protein [Mycobacterium tuberculosis T46] gi|289545636|gb|EFD49284.1| conserved membrane protein [Mycobacterium tuberculosis T17] gi|289696358|gb|EFD63787.1| transmembrane protein [Mycobacterium tuberculosis EAS054] Length=549 Score = 1078 bits (2789), Expect = 0.0, Method: Compositional matrix adjust. Identities = 548/549 (99%), Positives = 548/549 (99%), Gaps = 0/549 (0%) Query 1 MDAEAFVGFRQVPAARYGGLMATTAALPRRIHAFVRWVVRTPWPLFSLSMLQSDIIGALF 60 MDAEAFVGFRQVPAARYGGLMATTAALPRRIHAFVRWVVRTPWPLFSLSMLQSDIIGALF Sbjct 1 MDAEAFVGFRQVPAARYGGLMATTAALPRRIHAFVRWVVRTPWPLFSLSMLQSDIIGALF 60 Query 61 VLGFLRYGLPPQDNIQLQDLPPVNLLIFVSTVIILFLAGAVVNLKLLMPVFRWQRRDNLL 120 VLGFLRYGLPPQDNIQLQDLPPVNLLIFVSTVIILFLAGAVVNLKLLMPVFRWQRRDNLL Sbjct 61 VLGFLRYGLPPQDNIQLQDLPPVNLLIFVSTVIILFLAGAVVNLKLLMPVFRWQRRDNLL 120 Query 121 TEPDPAATELARSRALRMPLYRTLISLAVWATGGGVFILASWSVAKHAAPVVAVATALGA 180 TEPDPAATELARSRALRMPLYRTLISLAVWATGGGVFILASWSVAKHAAPVVAVATALGA Sbjct 121 TEPDPAATELARSRALRMPLYRTLISLAVWATGGGVFILASWSVAKHAAPVVAVATALGA 180 Query 181 TATAIIGYLQSERVLRPVAVAALRSGVPENVNAPGVILRLMLAWIPSTGVPLLAIVLAVA 240 TATA IGYLQSERVLRPVAVAALRSGVPENVNAPGVILRLMLAWIPSTGVPLLAIVLAVA Sbjct 181 TATASIGYLQSERVLRPVAVAALRSGVPENVNAPGVILRLMLAWIPSTGVPLLAIVLAVA 240 Query 241 ADKIALLHATPEALFNPILMMALAALGIGSVSTLLVAMSIADPLRQLRWALSEVQRGNYN 300 ADKIALLHATPEALFNPILMMALAALGIGSVSTLLVAMSIADPLRQLRWALSEVQRGNYN Sbjct 241 ADKIALLHATPEALFNPILMMALAALGIGSVSTLLVAMSIADPLRQLRWALSEVQRGNYN 300 Query 301 AHMQIYDASELGLLQAGFNDMVRELSERQRLRDLFGRYVGEDVARRALERGTELGGQERD 360 AHMQIYDASELGLLQAGFNDMVRELSERQRLRDLFGRYVGEDVARRALERGTELGGQERD Sbjct 301 AHMQIYDASELGLLQAGFNDMVRELSERQRLRDLFGRYVGEDVARRALERGTELGGQERD 360 Query 361 VAVLFVDLVGSTQLAATRPPAEVVQLLNEFFRVVVETVARHGGFVNKFQGDAALAIFGAP 420 VAVLFVDLVGSTQLAATRPPAEVVQLLNEFFRVVVETVARHGGFVNKFQGDAALAIFGAP Sbjct 361 VAVLFVDLVGSTQLAATRPPAEVVQLLNEFFRVVVETVARHGGFVNKFQGDAALAIFGAP 420 Query 421 IEHPDGAGAALSAARELHDELIPVLGSAEFGIGVSAGRAIAGHIGAQARFEYTVIGDPVN 480 IEHPDGAGAALSAARELHDELIPVLGSAEFGIGVSAGRAIAGHIGAQARFEYTVIGDPVN Sbjct 421 IEHPDGAGAALSAARELHDELIPVLGSAEFGIGVSAGRAIAGHIGAQARFEYTVIGDPVN 480 Query 481 EAARLTELAKLEDGHVLASAIAVSGALDAEALCWDVGEVVELRGRAAPTQLARPMNLAAP 540 EAARLTELAKLEDGHVLASAIAVSGALDAEALCWDVGEVVELRGRAAPTQLARPMNLAAP Sbjct 481 EAARLTELAKLEDGHVLASAIAVSGALDAEALCWDVGEVVELRGRAAPTQLARPMNLAAP 540 Query 541 EEVSSEVRG 549 EEVSSEVRG Sbjct 541 EEVSSEVRG 549 >gi|339633637|ref|YP_004725279.1| hypothetical protein MAF_36520 [Mycobacterium africanum GM041182] gi|339332993|emb|CCC28721.1| putative conserved transmembrane protein [Mycobacterium africanum GM041182] Length=549 Score = 1078 bits (2788), Expect = 0.0, Method: Compositional matrix adjust. Identities = 547/549 (99%), Positives = 547/549 (99%), Gaps = 0/549 (0%) Query 1 MDAEAFVGFRQVPAARYGGLMATTAALPRRIHAFVRWVVRTPWPLFSLSMLQSDIIGALF 60 MDAEAFVGFRQVPAARYGGLMATTAALPRRIHAFVRWVVRTPWPLFSLSMLQSDIIGALF Sbjct 1 MDAEAFVGFRQVPAARYGGLMATTAALPRRIHAFVRWVVRTPWPLFSLSMLQSDIIGALF 60 Query 61 VLGFLRYGLPPQDNIQLQDLPPVNLLIFVSTVIILFLAGAVVNLKLLMPVFRWQRRDNLL 120 VLGFLRYGLPPQDNIQLQDLPPVNLLIFVSTVIILFLAGAVVNLKLLMPVFRWQRRDNLL Sbjct 61 VLGFLRYGLPPQDNIQLQDLPPVNLLIFVSTVIILFLAGAVVNLKLLMPVFRWQRRDNLL 120 Query 121 TEPDPAATELARSRALRMPLYRTLISLAVWATGGGVFILASWSVAKHAAPVVAVATALGA 180 TEPDP ATELARSRALRMPLYRTLISLAVWATGGGVFILASWSVAKHAAPVVAVATALGA Sbjct 121 TEPDPTATELARSRALRMPLYRTLISLAVWATGGGVFILASWSVAKHAAPVVAVATALGA 180 Query 181 TATAIIGYLQSERVLRPVAVAALRSGVPENVNAPGVILRLMLAWIPSTGVPLLAIVLAVA 240 TATAIIGYLQSERVLRPVAVAALRSGVPENVNAPGVILRLMLAWIPSTGVPLLAIVLAVA Sbjct 181 TATAIIGYLQSERVLRPVAVAALRSGVPENVNAPGVILRLMLAWIPSTGVPLLAIVLAVA 240 Query 241 ADKIALLHATPEALFNPILMMALAALGIGSVSTLLVAMSIADPLRQLRWALSEVQRGNYN 300 ADKIALLHATPEALFNPILMMALAALGIGSVSTLLVAMSIADPLRQLRWALSEVQRGNYN Sbjct 241 ADKIALLHATPEALFNPILMMALAALGIGSVSTLLVAMSIADPLRQLRWALSEVQRGNYN 300 Query 301 AHMQIYDASELGLLQAGFNDMVRELSERQRLRDLFGRYVGEDVARRALERGTELGGQERD 360 AHMQIYDASELGLLQAGFNDMVRELSERQRLRDLFGRYVGEDVARRALERGTELGGQERD Sbjct 301 AHMQIYDASELGLLQAGFNDMVRELSERQRLRDLFGRYVGEDVARRALERGTELGGQERD 360 Query 361 VAVLFVDLVGSTQLAATRPPAEVVQLLNEFFRVVVETVARHGGFVNKFQGDAALAIFGAP 420 VAVLFVDLVGSTQLAATRPPAEVVQLLNEFFRVVVETVARH GFVNKFQGDAALAIFGAP Sbjct 361 VAVLFVDLVGSTQLAATRPPAEVVQLLNEFFRVVVETVARHSGFVNKFQGDAALAIFGAP 420 Query 421 IEHPDGAGAALSAARELHDELIPVLGSAEFGIGVSAGRAIAGHIGAQARFEYTVIGDPVN 480 IEHPDGAGAALSAARELHDELIPVLGSAEFGIGVSAGRAIAGHIGAQARFEYTVIGDPVN Sbjct 421 IEHPDGAGAALSAARELHDELIPVLGSAEFGIGVSAGRAIAGHIGAQARFEYTVIGDPVN 480 Query 481 EAARLTELAKLEDGHVLASAIAVSGALDAEALCWDVGEVVELRGRAAPTQLARPMNLAAP 540 EAARLTELAKLEDGHVLASAIAVSGALDAEALCWDVGEVVELRGRAAPTQLARPMNLAAP Sbjct 481 EAARLTELAKLEDGHVLASAIAVSGALDAEALCWDVGEVVELRGRAAPTQLARPMNLAAP 540 Query 541 EEVSSEVRG 549 EEVSSEVRG Sbjct 541 EEVSSEVRG 549 >gi|167968567|ref|ZP_02550844.1| conserved transmembrane protein [Mycobacterium tuberculosis H37Ra] Length=547 Score = 974 bits (2519), Expect = 0.0, Method: Compositional matrix adjust. Identities = 527/554 (96%), Positives = 528/554 (96%), Gaps = 12/554 (2%) Query 1 MDAEAFVGFRQVPAARYGGLMATTAALPRRIHAFVRWVVRTPWPLFSLSMLQSDIIGALF 60 MDAEAFVGFRQVPAARYGGLMATTAALPRRIHAFVRWVVRTPWPLFSLSMLQSDIIGALF Sbjct 1 MDAEAFVGFRQVPAARYGGLMATTAALPRRIHAFVRWVVRTPWPLFSLSMLQSDIIGALF 60 Query 61 VLGFLRYGLPPQDNIQLQDLPPVNLLIFVSTVIILFLAGAVVNLKLLMPVFRWQRRDNLL 120 VLGFLRYGLPPQDNIQLQDLPPVNLLIFVSTVIILFLAGAVVNLKLLMPVFRWQRRDNLL Sbjct 61 VLGFLRYGLPPQDNIQLQDLPPVNLLIFVSTVIILFLAGAVVNLKLLMPVFRWQRRDNLL 120 Query 121 TEPDPAATELARSRALRMPLYRTLISLAVWATGGGVFILASWSVAKHAAPVVAVATALGA 180 TEPDPAATELARSRALRMPLYRTLISLAVWATGGGVFILASWSVAKHAAPVVAVATALGA Sbjct 121 TEPDPAATELARSRALRMPLYRTLISLAVWATGGGVFILASWSVAKHAAPVVAVATALGA 180 Query 181 TATAIIGYLQSERVLRPVAVAALRSGVPENVNAPGVILRLMLAWIPSTGVPLLAIVLAVA 240 TATAIIGYLQSERVLRPVAVAALRSGVPENVNAPGVILRLMLAWIPSTGVPLLAIVLAVA Sbjct 181 TATAIIGYLQSERVLRPVAVAALRSGVPENVNAPGVILRLMLAWIPSTGVPLLAIVLAVA 240 Query 241 ADKIALLHATPEALFNPILMMALAALGIGSVSTLLVAMSIADPLRQLRWALSEVQRGNYN 300 ADKIALLHATPEALFNPILMMALAALGIGSVSTLLVAMSIADPLRQLRWALSEVQRGNYN Sbjct 241 ADKIALLHATPEALFNPILMMALAALGIGSVSTLLVAMSIADPLRQLRWALSEVQRGNYN 300 Query 301 AHMQIYDASELGLLQAGFNDMVRELSERQRLRDLFGRYVGEDVARRALERGTELGGQERD 360 AHMQIYDASELGLLQAGFNDMVRELSERQRLRDLFGRYVGEDVARRALERGTELGGQERD Sbjct 301 AHMQIYDASELGLLQAGFNDMVRELSERQRLRDLFGRYVGEDVARRALERGTELGGQERD 360 Query 361 VAVLFVDLVGSTQLAATRPPAEVVQLLNEFFRVVVETVARHGGFVNKFQGDAALAIFGAP 420 VAVLFVDLVGSTQLAATRPPAEVVQLLNEFFRVVVETVARHGGFVNKFQGDAALAIFGAP Sbjct 361 VAVLFVDLVGSTQLAATRPPAEVVQLLNEFFRVVVETVARHGGFVNKFQGDAALAIFGAP 420 Query 421 IEHPDGAGAALSAARELHDELIPVLGSAEFGIGVSAGRAIAGHIGAQARFEYTVIGDPVN 480 IEHPDGAGAALSAARELHDELIPVLGSAEFGIGVSAGRAIAGHIGAQARFEYTVIGDPVN Sbjct 421 IEHPDGAGAALSAARELHDELIPVLGSAEFGIGVSAGRAIAGHIGAQARFEYTVIGDPVN 480 Query 481 EAARLTELAKLEDGHVLASAIAVSGALDAEALCWDVGEVVELRGR-----AAPTQLARPM 535 EAARLTELAKLEDGHVLASAIAVSGA W V + R T RPM Sbjct 481 EAARLTELAKLEDGHVLASAIAVSGA-------WTPKHCVGMLARWLSSADVCTHPYRPM 533 Query 536 NLAAPEEVSSEVRG 549 NLAAPEEVSSEVRG Sbjct 534 NLAAPEEVSSEVRG 547 >gi|41406524|ref|NP_959360.1| hypothetical protein MAP0426c [Mycobacterium avium subsp. paratuberculosis K-10] gi|41394873|gb|AAS02743.1| hypothetical protein MAP_0426c [Mycobacterium avium subsp. paratuberculosis K-10] Length=553 Score = 899 bits (2324), Expect = 0.0, Method: Compositional matrix adjust. Identities = 461/546 (85%), Positives = 493/546 (91%), Gaps = 5/546 (0%) Query 9 FRQVPAARYGGLMATTAALPRRIHAFVRWVVRTPWPLFSLSMLQSDIIGALFVLGFLRYG 68 FR V AARYGG++ T AALP RI AF RWVVRTPWPLF LSM+Q+DIIGALFVLGFLRY Sbjct 8 FRDVAAARYGGIVTTAAALPGRISAFARWVVRTPWPLFWLSMMQADIIGALFVLGFLRYA 67 Query 69 LPPQDNIQLQDLPPVNLLIFVSTVIILFLAGAVVNLKLLMPVFRWQRRDNLLTEPDPAAT 128 LPP+D IQLQDLP VNL +F +++++LFLA +VVNL LLMPVFRWQRRDNLL E DPAAT Sbjct 68 LPPEDRIQLQDLPVVNLAVFATSLVVLFLAASVVNLTLLMPVFRWQRRDNLLAESDPAAT 127 Query 129 ELARSRALRMPLYRTLISLAVWATGGGVFILASWSVAKHAAPVVAVATALGATATAIIGY 188 ELAR RALRMP YRT+ S+ +W GG VFI+ASWSVA+ AAPVVAVAT LGA ATAIIGY Sbjct 128 ELARIRALRMPFYRTVTSMVIWCIGGVVFIIASWSVARFAAPVVAVATGLGAAATAIIGY 187 Query 189 LQSERVLRPVAVAALRSGVPENVNAPGVILRLMLAWIPSTGVPLLAIVLAVAADKIALLH 248 LQ ERVLRPVAVAALRSGVPENV APGVILR +L W+ ST VP+LAIVLAV ADK +LLH Sbjct 188 LQCERVLRPVAVAALRSGVPENVKAPGVILRQILTWMLSTAVPVLAIVLAVVADKTSLLH 247 Query 249 ATPEALFNPILMMALAALGIGSVSTLLVAMSIADPLRQLRWALSEVQRGNYNAHMQIYDA 308 ATPE LF PIL++A+AALGIG VSTLLVAMSIADPLRQLRWALSEVQRGNYNAHMQIYDA Sbjct 248 ATPEKLFTPILLLAVAALGIGLVSTLLVAMSIADPLRQLRWALSEVQRGNYNAHMQIYDA 307 Query 309 SELGLLQAGFNDMVRELSERQRLRDLFGRYVGEDVARRALERGTELGGQERDVAVLFVDL 368 SELGLLQAGFNDMVR+LSERQRLRDLFGRYVGEDVARRALERGTELGGQERDVAVLFVDL Sbjct 308 SELGLLQAGFNDMVRDLSERQRLRDLFGRYVGEDVARRALERGTELGGQERDVAVLFVDL 367 Query 369 VGSTQLAATRPPAEVVQLLNEFFRVVVETVARHGGFVNKFQGDAALAIFGAPIEHPDGAG 428 VGSTQLAATRPPAEVV LLNEFFRVVVETV +HGGFVNKFQGDAALAIFGAPIEHPD G Sbjct 368 VGSTQLAATRPPAEVVHLLNEFFRVVVETVGKHGGFVNKFQGDAALAIFGAPIEHPDSPG 427 Query 429 AALSAARELHDELIPVLGSAEFGIGVSAGRAIAGHIGAQARFEYTVIGDPVNEAARLTEL 488 AL+AARELHD L+PV+GSAEFGIGVSAGRAIAGHIGAQARFEYTVIGDPVNEAARLTEL Sbjct 428 GALAAARELHDALLPVIGSAEFGIGVSAGRAIAGHIGAQARFEYTVIGDPVNEAARLTEL 487 Query 489 AKLEDGHVLASAIAVSGALDAEALCWDVGEVVELRGRAAPTQLARPMNLA-----APEEV 543 AKLE GHVLASAIAVSGALD+EALCWDVGEVVELRGR APTQLARP+ LA AP+EV Sbjct 488 AKLEPGHVLASAIAVSGALDSEALCWDVGEVVELRGRTAPTQLARPVKLATPEEVAPQEV 547 Query 544 SSEVRG 549 SSEV G Sbjct 548 SSEVSG 553 >gi|289763822|ref|ZP_06523200.1| adenylate cyclase [Mycobacterium tuberculosis GM 1503] gi|289711328|gb|EFD75344.1| adenylate cyclase [Mycobacterium tuberculosis GM 1503] Length=455 Score = 890 bits (2301), Expect = 0.0, Method: Compositional matrix adjust. Identities = 454/455 (99%), Positives = 455/455 (100%), Gaps = 0/455 (0%) Query 95 LFLAGAVVNLKLLMPVFRWQRRDNLLTEPDPAATELARSRALRMPLYRTLISLAVWATGG 154 +FLAGAVVNLKLLMPVFRWQRRDNLLTEPDPAATELARSRALRMPLYRTLISLAVWATGG Sbjct 1 MFLAGAVVNLKLLMPVFRWQRRDNLLTEPDPAATELARSRALRMPLYRTLISLAVWATGG 60 Query 155 GVFILASWSVAKHAAPVVAVATALGATATAIIGYLQSERVLRPVAVAALRSGVPENVNAP 214 GVFILASWSVAKHAAPVVAVATALGATATAIIGYLQSERVLRPVAVAALRSGVPENVNAP Sbjct 61 GVFILASWSVAKHAAPVVAVATALGATATAIIGYLQSERVLRPVAVAALRSGVPENVNAP 120 Query 215 GVILRLMLAWIPSTGVPLLAIVLAVAADKIALLHATPEALFNPILMMALAALGIGSVSTL 274 GVILRLMLAWIPSTGVPLLAIVLAVAADKIALLHATPEALFNPILMMALAALGIGSVSTL Sbjct 121 GVILRLMLAWIPSTGVPLLAIVLAVAADKIALLHATPEALFNPILMMALAALGIGSVSTL 180 Query 275 LVAMSIADPLRQLRWALSEVQRGNYNAHMQIYDASELGLLQAGFNDMVRELSERQRLRDL 334 LVAMSIADPLRQLRWALSEVQRGNYNAHMQIYDASELGLLQAGFNDMVRELSERQRLRDL Sbjct 181 LVAMSIADPLRQLRWALSEVQRGNYNAHMQIYDASELGLLQAGFNDMVRELSERQRLRDL 240 Query 335 FGRYVGEDVARRALERGTELGGQERDVAVLFVDLVGSTQLAATRPPAEVVQLLNEFFRVV 394 FGRYVGEDVARRALERGTELGGQERDVAVLFVDLVGSTQLAATRPPAEVVQLLNEFFRVV Sbjct 241 FGRYVGEDVARRALERGTELGGQERDVAVLFVDLVGSTQLAATRPPAEVVQLLNEFFRVV 300 Query 395 VETVARHGGFVNKFQGDAALAIFGAPIEHPDGAGAALSAARELHDELIPVLGSAEFGIGV 454 VETVARHGGFVNKFQGDAALAIFGAPIEHPDGAGAALSAARELHDELIPVLGSAEFGIGV Sbjct 301 VETVARHGGFVNKFQGDAALAIFGAPIEHPDGAGAALSAARELHDELIPVLGSAEFGIGV 360 Query 455 SAGRAIAGHIGAQARFEYTVIGDPVNEAARLTELAKLEDGHVLASAIAVSGALDAEALCW 514 SAGRAIAGHIGAQARFEYTVIGDPVNEAARLTELAKLEDGHVLASAIAVSGALDAEALCW Sbjct 361 SAGRAIAGHIGAQARFEYTVIGDPVNEAARLTELAKLEDGHVLASAIAVSGALDAEALCW 420 Query 515 DVGEVVELRGRAAPTQLARPMNLAAPEEVSSEVRG 549 DVGEVVELRGRAAPTQLARPMNLAAPEEVSSEVRG Sbjct 421 DVGEVVELRGRAAPTQLARPMNLAAPEEVSSEVRG 455 >gi|118465478|ref|YP_879800.1| adenylate cyclase, family protein 3 [Mycobacterium avium 104] gi|118166765|gb|ABK67662.1| adenylate cyclase, family protein 3 [Mycobacterium avium 104] Length=534 Score = 883 bits (2281), Expect = 0.0, Method: Compositional matrix adjust. Identities = 453/534 (85%), Positives = 483/534 (91%), Gaps = 5/534 (0%) Query 21 MATTAALPRRIHAFVRWVVRTPWPLFSLSMLQSDIIGALFVLGFLRYGLPPQDNIQLQDL 80 M T AALP RI AF RWVVRTPWPLF LSM+Q+DIIGALFVLGFLRY LPP+D IQLQDL Sbjct 1 MTTAAALPGRISAFARWVVRTPWPLFWLSMMQADIIGALFVLGFLRYALPPEDRIQLQDL 60 Query 81 PPVNLLIFVSTVIILFLAGAVVNLKLLMPVFRWQRRDNLLTEPDPAATELARSRALRMPL 140 P VNL +F +++++LFLA +VVNL LLMPVFRWQRRDNLL E DPAATELAR RALRMP Sbjct 61 PVVNLAVFATSLVVLFLAASVVNLTLLMPVFRWQRRDNLLAESDPAATELARIRALRMPF 120 Query 141 YRTLISLAVWATGGGVFILASWSVAKHAAPVVAVATALGATATAIIGYLQSERVLRPVAV 200 YRT+ S+ +W GG VFI+ASWSVA+ AAPVVAVAT LGA ATAIIGYLQ ERVLRPVAV Sbjct 121 YRTVTSMVIWCIGGVVFIIASWSVARFAAPVVAVATGLGAAATAIIGYLQCERVLRPVAV 180 Query 201 AALRSGVPENVNAPGVILRLMLAWIPSTGVPLLAIVLAVAADKIALLHATPEALFNPILM 260 AALRSGVPENV APGVILR +L W+ ST VP+LAIVLAV ADK +LLHATPE LF PIL+ Sbjct 181 AALRSGVPENVKAPGVILRQILTWMLSTAVPVLAIVLAVVADKTSLLHATPEKLFTPILL 240 Query 261 MALAALGIGSVSTLLVAMSIADPLRQLRWALSEVQRGNYNAHMQIYDASELGLLQAGFND 320 +A+AALGIG VSTLLVAMSIADPLRQLRWALSEVQRGNYNAHMQIYDASELGLLQAGFND Sbjct 241 LAVAALGIGLVSTLLVAMSIADPLRQLRWALSEVQRGNYNAHMQIYDASELGLLQAGFND 300 Query 321 MVRELSERQRLRDLFGRYVGEDVARRALERGTELGGQERDVAVLFVDLVGSTQLAATRPP 380 MVR+LSERQRLRDLFGRYVGEDVARRALERGTELGGQERDVAVLFVDLVGSTQLAATRPP Sbjct 301 MVRDLSERQRLRDLFGRYVGEDVARRALERGTELGGQERDVAVLFVDLVGSTQLAATRPP 360 Query 381 AEVVQLLNEFFRVVVETVARHGGFVNKFQGDAALAIFGAPIEHPDGAGAALSAARELHDE 440 AEVV LLNEFFRVVVETV +HGGFVNKFQGDAALAIFGAPIEHPD G AL+AARELHD Sbjct 361 AEVVHLLNEFFRVVVETVGKHGGFVNKFQGDAALAIFGAPIEHPDSPGGALAAARELHDA 420 Query 441 LIPVLGSAEFGIGVSAGRAIAGHIGAQARFEYTVIGDPVNEAARLTELAKLEDGHVLASA 500 L+PV+GSAEFGIGVSAGRAIAGHIGAQARFEYTVIGDPVNEAARLTELAKLE GHVLASA Sbjct 421 LLPVIGSAEFGIGVSAGRAIAGHIGAQARFEYTVIGDPVNEAARLTELAKLEPGHVLASA 480 Query 501 IAVSGALDAEALCWDVGEVVELRGRAAPTQLARPMNLA-----APEEVSSEVRG 549 IAVSGALD+EALCWDVGEVVELRGR APTQLARP+ LA AP+EVSSEV G Sbjct 481 IAVSGALDSEALCWDVGEVVELRGRTAPTQLARPVKLATPEEVAPQEVSSEVSG 534 >gi|240173038|ref|ZP_04751696.1| putative transmembrane protein [Mycobacterium kansasii ATCC 12478] Length=543 Score = 881 bits (2277), Expect = 0.0, Method: Compositional matrix adjust. Identities = 472/541 (88%), Positives = 497/541 (92%), Gaps = 0/541 (0%) Query 7 VGFRQVPAARYGGLMATTAALPRRIHAFVRWVVRTPWPLFSLSMLQSDIIGALFVLGFLR 66 + FR V A YGGL+AT AALP RI AF RWVVRTPWP+FSLSMLQSDIIGALFVLGFLR Sbjct 1 MSFRPVTTAGYGGLVATVAALPGRISAFARWVVRTPWPVFSLSMLQSDIIGALFVLGFLR 60 Query 67 YGLPPQDNIQLQDLPPVNLLIFVSTVIILFLAGAVVNLKLLMPVFRWQRRDNLLTEPDPA 126 YGLPP D IQLQDLP +NL+IFV + ++F AG N KLL+PVFRWQRRDNLL E DPA Sbjct 61 YGLPPGDRIQLQDLPRLNLVIFVLSAHVVFFAGVAANFKLLVPVFRWQRRDNLLAEADPA 120 Query 127 ATELARSRALRMPLYRTLISLAVWATGGGVFILASWSVAKHAAPVVAVATALGATATAII 186 ATELAR R LRMP YRT++SL VWA G VFI+ASWSVA++AAPVVAVATALGATATAII Sbjct 121 ATELARRRVLRMPFYRTVVSLVVWAIGSAVFIVASWSVARYAAPVVAVATALGATATAII 180 Query 187 GYLQSERVLRPVAVAALRSGVPENVNAPGVILRLMLAWIPSTGVPLLAIVLAVAADKIAL 246 GYLQSERVLRPVAVAALRSGVPEN+ PGVILRLMLAW+ ST VPLLAIVLAV +DKIAL Sbjct 181 GYLQSERVLRPVAVAALRSGVPENLRTPGVILRLMLAWVLSTAVPLLAIVLAVVSDKIAL 240 Query 247 LHATPEALFNPILMMALAALGIGSVSTLLVAMSIADPLRQLRWALSEVQRGNYNAHMQIY 306 LH PE LF+PIL++ALAALGIG VSTLLVAMSIADPLRQLRWALSEVQRGNYNAHMQIY Sbjct 241 LHTAPEKLFDPILLLALAALGIGFVSTLLVAMSIADPLRQLRWALSEVQRGNYNAHMQIY 300 Query 307 DASELGLLQAGFNDMVRELSERQRLRDLFGRYVGEDVARRALERGTELGGQERDVAVLFV 366 DASELGLLQAGFNDMVR+LSERQRLRDLFGRYVGEDVARRA+ERGTELGGQERDVAVLFV Sbjct 301 DASELGLLQAGFNDMVRDLSERQRLRDLFGRYVGEDVARRAIERGTELGGQERDVAVLFV 360 Query 367 DLVGSTQLAATRPPAEVVQLLNEFFRVVVETVARHGGFVNKFQGDAALAIFGAPIEHPDG 426 DLVGSTQLAATRPPAEVV LLNEFFRVVV+TV RHGGFVNKFQGDAALAIFGAPIEHPDG Sbjct 361 DLVGSTQLAATRPPAEVVHLLNEFFRVVVDTVGRHGGFVNKFQGDAALAIFGAPIEHPDG 420 Query 427 AGAALSAARELHDELIPVLGSAEFGIGVSAGRAIAGHIGAQARFEYTVIGDPVNEAARLT 486 AGAAL AARELHD LIPVLGSAEFGIGVSAGRAIAGHIGAQARFEYTVIGDPVNEAARLT Sbjct 421 AGAALCAARELHDALIPVLGSAEFGIGVSAGRAIAGHIGAQARFEYTVIGDPVNEAARLT 480 Query 487 ELAKLEDGHVLASAIAVSGALDAEALCWDVGEVVELRGRAAPTQLARPMNLAAPEEVSSE 546 ELAKLE GHVLASAIAVSGALDAEALCWDV EVVELRGRAAPTQLARP+NLAAPEEVSSE Sbjct 481 ELAKLEAGHVLASAIAVSGALDAEALCWDVAEVVELRGRAAPTQLARPLNLAAPEEVSSE 540 Query 547 V 547 + Sbjct 541 M 541 >gi|336460891|gb|EGO39775.1| family 3 adenylate cyclase [Mycobacterium avium subsp. paratuberculosis S397] Length=534 Score = 880 bits (2275), Expect = 0.0, Method: Compositional matrix adjust. Identities = 452/534 (85%), Positives = 482/534 (91%), Gaps = 5/534 (0%) Query 21 MATTAALPRRIHAFVRWVVRTPWPLFSLSMLQSDIIGALFVLGFLRYGLPPQDNIQLQDL 80 M T AALP RI AF RWVVRTPWPLF LSM+Q+DIIGALFVLGFLRY LPP+D IQLQDL Sbjct 1 MTTAAALPGRISAFARWVVRTPWPLFWLSMMQADIIGALFVLGFLRYALPPEDRIQLQDL 60 Query 81 PPVNLLIFVSTVIILFLAGAVVNLKLLMPVFRWQRRDNLLTEPDPAATELARSRALRMPL 140 P VNL +F +++++LFLA +VVNL LLMPVFRWQRRDNLL E DPAATELAR RALRMP Sbjct 61 PVVNLAVFATSLVVLFLAASVVNLTLLMPVFRWQRRDNLLAESDPAATELARIRALRMPF 120 Query 141 YRTLISLAVWATGGGVFILASWSVAKHAAPVVAVATALGATATAIIGYLQSERVLRPVAV 200 YRT+ S+ +W GG VFI+ASWSVA+ AAPVVAVAT LGA ATAIIGYLQ ERVLRPVAV Sbjct 121 YRTVTSMVIWCIGGVVFIIASWSVARFAAPVVAVATGLGAAATAIIGYLQCERVLRPVAV 180 Query 201 AALRSGVPENVNAPGVILRLMLAWIPSTGVPLLAIVLAVAADKIALLHATPEALFNPILM 260 AALRSGVPENV APGVILR +L W+ ST VP+LAIVLAV ADK +LLHATPE LF PIL+ Sbjct 181 AALRSGVPENVKAPGVILRQILTWMLSTVVPVLAIVLAVVADKTSLLHATPEKLFTPILL 240 Query 261 MALAALGIGSVSTLLVAMSIADPLRQLRWALSEVQRGNYNAHMQIYDASELGLLQAGFND 320 +A+AALGIG VSTLLVAMSIADPLRQLRWALSEVQRGNYNAHMQIYDASELGLLQAGFND Sbjct 241 LAVAALGIGLVSTLLVAMSIADPLRQLRWALSEVQRGNYNAHMQIYDASELGLLQAGFND 300 Query 321 MVRELSERQRLRDLFGRYVGEDVARRALERGTELGGQERDVAVLFVDLVGSTQLAATRPP 380 MVR+LSERQRLRDLFGRYVGEDVARRALERGTELGGQERDVAVLFVDLVGSTQLAATRPP Sbjct 301 MVRDLSERQRLRDLFGRYVGEDVARRALERGTELGGQERDVAVLFVDLVGSTQLAATRPP 360 Query 381 AEVVQLLNEFFRVVVETVARHGGFVNKFQGDAALAIFGAPIEHPDGAGAALSAARELHDE 440 AEVV LLNEFFRVVVETV +HGGFVNKFQGDAALAIFGAPIEHPD G AL+AARELHD Sbjct 361 AEVVHLLNEFFRVVVETVGKHGGFVNKFQGDAALAIFGAPIEHPDSPGGALAAARELHDA 420 Query 441 LIPVLGSAEFGIGVSAGRAIAGHIGAQARFEYTVIGDPVNEAARLTELAKLEDGHVLASA 500 L+PV+GSAEFGIGVSAGRAIAGHIG QARFEYTVIGDPVNEAARLTELAKLE GHVLASA Sbjct 421 LLPVIGSAEFGIGVSAGRAIAGHIGTQARFEYTVIGDPVNEAARLTELAKLEPGHVLASA 480 Query 501 IAVSGALDAEALCWDVGEVVELRGRAAPTQLARPMNLA-----APEEVSSEVRG 549 IAVSGALD+EALCWDVGEVVELRGR APTQLARP+ LA AP+EVSSEV G Sbjct 481 IAVSGALDSEALCWDVGEVVELRGRTAPTQLARPVKLATPEEVAPQEVSSEVSG 534 >gi|296166700|ref|ZP_06849125.1| adenylate cyclase, family protein 3 [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295897965|gb|EFG77546.1| adenylate cyclase, family protein 3 [Mycobacterium parascrofulaceum ATCC BAA-614] Length=536 Score = 880 bits (2275), Expect = 0.0, Method: Compositional matrix adjust. Identities = 460/529 (87%), Positives = 487/529 (93%), Gaps = 0/529 (0%) Query 21 MATTAALPRRIHAFVRWVVRTPWPLFSLSMLQSDIIGALFVLGFLRYGLPPQDNIQLQDL 80 MAT AALP RI AFVRWVVRTPWPLFSLSMLQ+DIIGALFVLGFLRY LPP+D IQLQDL Sbjct 1 MATPAALPGRISAFVRWVVRTPWPLFSLSMLQADIIGALFVLGFLRYALPPEDRIQLQDL 60 Query 81 PPVNLLIFVSTVIILFLAGAVVNLKLLMPVFRWQRRDNLLTEPDPAATELARSRALRMPL 140 P +NL +F + +++LFLAG +VNLKLLMPVFRWQRRDNLL E DPAATELARSRALRMP Sbjct 61 PVLNLAVFGTALVVLFLAGWMVNLKLLMPVFRWQRRDNLLAEADPAATELARSRALRMPF 120 Query 141 YRTLISLAVWATGGGVFILASWSVAKHAAPVVAVATALGATATAIIGYLQSERVLRPVAV 200 YRTLIS+ W GG VFI+ASWSVA+ AAPVVAVAT LGA ATAIIGYLQSERVLRPVAV Sbjct 121 YRTLISMVAWLIGGVVFIIASWSVARFAAPVVAVATGLGAAATAIIGYLQSERVLRPVAV 180 Query 201 AALRSGVPENVNAPGVILRLMLAWIPSTGVPLLAIVLAVAADKIALLHATPEALFNPILM 260 AALRSGVPENV APGVILR +L W+ ST VP+LAIVLAV ADK +LLHATPE LF PIL+ Sbjct 181 AALRSGVPENVQAPGVILRQILTWMLSTAVPVLAIVLAVMADKASLLHATPEKLFTPILL 240 Query 261 MALAALGIGSVSTLLVAMSIADPLRQLRWALSEVQRGNYNAHMQIYDASELGLLQAGFND 320 +ALAALGIG VSTLLVAMSIADPLRQLRWALSEVQRGNYNAHMQIYDASELGLLQAGFND Sbjct 241 LALAALGIGFVSTLLVAMSIADPLRQLRWALSEVQRGNYNAHMQIYDASELGLLQAGFND 300 Query 321 MVRELSERQRLRDLFGRYVGEDVARRALERGTELGGQERDVAVLFVDLVGSTQLAATRPP 380 MVR+LSERQRLRDLFGRYVGEDVARRALERGTELGGQER VAVLFVDLVGST+LAATRPP Sbjct 301 MVRDLSERQRLRDLFGRYVGEDVARRALERGTELGGQERHVAVLFVDLVGSTKLAATRPP 360 Query 381 AEVVQLLNEFFRVVVETVARHGGFVNKFQGDAALAIFGAPIEHPDGAGAALSAARELHDE 440 AEVV LLNEFFRVVVETV RHGGFVNKFQGDAALAIFGAPIEHPD +G AL+AARELHDE Sbjct 361 AEVVHLLNEFFRVVVETVGRHGGFVNKFQGDAALAIFGAPIEHPDASGGALAAARELHDE 420 Query 441 LIPVLGSAEFGIGVSAGRAIAGHIGAQARFEYTVIGDPVNEAARLTELAKLEDGHVLASA 500 L+PV+GSAEFGIGVSAGRAIAGHIGAQARFEYTVIGDPVNEAARLTELAKLE GHVLASA Sbjct 421 LLPVIGSAEFGIGVSAGRAIAGHIGAQARFEYTVIGDPVNEAARLTELAKLEAGHVLASA 480 Query 501 IAVSGALDAEALCWDVGEVVELRGRAAPTQLARPMNLAAPEEVSSEVRG 549 IAVSGALDAEALCWDVGEVVELRGR APTQLARP+ LA EEV+SE +G Sbjct 481 IAVSGALDAEALCWDVGEVVELRGRTAPTQLARPVKLAGLEEVTSEPKG 529 >gi|183985105|ref|YP_001853396.1| adenylate cyclase [Mycobacterium marinum M] gi|183178431|gb|ACC43541.1| adenylate cyclase [Mycobacterium marinum M] Length=529 Score = 880 bits (2274), Expect = 0.0, Method: Compositional matrix adjust. Identities = 453/526 (87%), Positives = 489/526 (93%), Gaps = 0/526 (0%) Query 21 MATTAALPRRIHAFVRWVVRTPWPLFSLSMLQSDIIGALFVLGFLRYGLPPQDNIQLQDL 80 MAT A LP RI+ F RWVVRTPWP+FSLSMLQ+DIIG LFVLGFLRYGLPP D IQLQDL Sbjct 1 MATVATLPGRINGFARWVVRTPWPVFSLSMLQADIIGGLFVLGFLRYGLPPNDRIQLQDL 60 Query 81 PPVNLLIFVSTVIILFLAGAVVNLKLLMPVFRWQRRDNLLTEPDPAATELARSRALRMPL 140 PP+NL IF+++VI LFLAG +NLKLL+PVFRWQRRDNL+ DP+ATELARSR LRMP Sbjct 61 PPLNLAIFLTSVITLFLAGFALNLKLLVPVFRWQRRDNLVAAADPSATELARSRVLRMPF 120 Query 141 YRTLISLAVWATGGGVFILASWSVAKHAAPVVAVATALGATATAIIGYLQSERVLRPVAV 200 YRTLIS+ WA G +FI+ASWSVA++AAPVVA+ATALGA ATAIIGYLQSERVLRPVAV Sbjct 121 YRTLISVGSWAIGSVIFIVASWSVARYAAPVVAIATALGAIATAIIGYLQSERVLRPVAV 180 Query 201 AALRSGVPENVNAPGVILRLMLAWIPSTGVPLLAIVLAVAADKIALLHATPEALFNPILM 260 AALRSGVPEN+ +PGVILRLMLAW+ ST VPLLAIVLAV ADK+A+LHATP+ LFNPIL+ Sbjct 181 AALRSGVPENLRSPGVILRLMLAWVLSTAVPLLAIVLAVVADKMAILHATPDKLFNPILL 240 Query 261 MALAALGIGSVSTLLVAMSIADPLRQLRWALSEVQRGNYNAHMQIYDASELGLLQAGFND 320 +ALAAL IGS STLLV+MSIADPLRQLRWALSEVQRGNYNAHMQIYDASELGLLQAGFND Sbjct 241 LALAALAIGSASTLLVSMSIADPLRQLRWALSEVQRGNYNAHMQIYDASELGLLQAGFND 300 Query 321 MVRELSERQRLRDLFGRYVGEDVARRALERGTELGGQERDVAVLFVDLVGSTQLAATRPP 380 MVR+LSERQRLRDLFGRYVGEDVARRA+ERGTELGGQERDVAVLFVDLVGSTQLAATRPP Sbjct 301 MVRDLSERQRLRDLFGRYVGEDVARRAIERGTELGGQERDVAVLFVDLVGSTQLAATRPP 360 Query 381 AEVVQLLNEFFRVVVETVARHGGFVNKFQGDAALAIFGAPIEHPDGAGAALSAARELHDE 440 EVV LLNEFFRVVV+TVARHGGFVNKFQGDAALAIFGAPIEHPDGAGAAL AARELHDE Sbjct 361 VEVVGLLNEFFRVVVDTVARHGGFVNKFQGDAALAIFGAPIEHPDGAGAALRAARELHDE 420 Query 441 LIPVLGSAEFGIGVSAGRAIAGHIGAQARFEYTVIGDPVNEAARLTELAKLEDGHVLASA 500 LIPVLGSAEFGIGVSAGRAIAGHIGAQARFEYTVIGDPVNEAARLTELAKLE+GHVLASA Sbjct 421 LIPVLGSAEFGIGVSAGRAIAGHIGAQARFEYTVIGDPVNEAARLTELAKLEEGHVLASA 480 Query 501 IAVSGALDAEALCWDVGEVVELRGRAAPTQLARPMNLAAPEEVSSE 546 IA+SGALDAEALCWDV EVVELRGR APTQLARP+NLA ++VS++ Sbjct 481 IAISGALDAEALCWDVAEVVELRGRTAPTQLARPLNLAVAQQVSTK 526 >gi|118619391|ref|YP_907723.1| adenylate cyclase [Mycobacterium ulcerans Agy99] gi|118571501|gb|ABL06252.1| adenylate cyclase [Mycobacterium ulcerans Agy99] Length=529 Score = 876 bits (2264), Expect = 0.0, Method: Compositional matrix adjust. Identities = 451/526 (86%), Positives = 487/526 (93%), Gaps = 0/526 (0%) Query 21 MATTAALPRRIHAFVRWVVRTPWPLFSLSMLQSDIIGALFVLGFLRYGLPPQDNIQLQDL 80 MAT A LP RI+ F RWVVRTPWP+FSLSMLQ+DIIG LFVLGFLRYGLPP D IQLQDL Sbjct 1 MATVATLPGRINGFARWVVRTPWPVFSLSMLQADIIGGLFVLGFLRYGLPPNDRIQLQDL 60 Query 81 PPVNLLIFVSTVIILFLAGAVVNLKLLMPVFRWQRRDNLLTEPDPAATELARSRALRMPL 140 PP+NL IF+++VI LFLAG +NLKLL+PVFRWQRRDNL+ DP+ATELARSR LRMP Sbjct 61 PPLNLAIFLTSVITLFLAGFALNLKLLVPVFRWQRRDNLVAAADPSATELARSRVLRMPF 120 Query 141 YRTLISLAVWATGGGVFILASWSVAKHAAPVVAVATALGATATAIIGYLQSERVLRPVAV 200 YRTLIS+ WA G +FI+ASWSVA++AAPVVA+ATALGA ATAIIGYLQSERVLRPVAV Sbjct 121 YRTLISVGSWAIGSVIFIVASWSVARYAAPVVAIATALGAIATAIIGYLQSERVLRPVAV 180 Query 201 AALRSGVPENVNAPGVILRLMLAWIPSTGVPLLAIVLAVAADKIALLHATPEALFNPILM 260 AALRSGVPEN+ +PGVI RLMLAW+ ST VPLLAIVLAV ADK+A+LHATP+ LFNPIL+ Sbjct 181 AALRSGVPENLRSPGVISRLMLAWVLSTAVPLLAIVLAVVADKMAILHATPDKLFNPILL 240 Query 261 MALAALGIGSVSTLLVAMSIADPLRQLRWALSEVQRGNYNAHMQIYDASELGLLQAGFND 320 +ALAAL IGS STLLV+MSIADPLRQLRWALSEVQRGNYNAHMQIYDASELGLLQAGFND Sbjct 241 LALAALAIGSASTLLVSMSIADPLRQLRWALSEVQRGNYNAHMQIYDASELGLLQAGFND 300 Query 321 MVRELSERQRLRDLFGRYVGEDVARRALERGTELGGQERDVAVLFVDLVGSTQLAATRPP 380 MVR+LSERQRLRDLFGRYVGEDVARRA+ERGTELGGQERDVAVLFVDLVGSTQLAATRPP Sbjct 301 MVRDLSERQRLRDLFGRYVGEDVARRAIERGTELGGQERDVAVLFVDLVGSTQLAATRPP 360 Query 381 AEVVQLLNEFFRVVVETVARHGGFVNKFQGDAALAIFGAPIEHPDGAGAALSAARELHDE 440 EVV LLNEFFRVVV+TVARHGGFVNKFQGDAALAIFGAPIEHPDGAGAAL AARELHDE Sbjct 361 VEVVGLLNEFFRVVVDTVARHGGFVNKFQGDAALAIFGAPIEHPDGAGAALRAARELHDE 420 Query 441 LIPVLGSAEFGIGVSAGRAIAGHIGAQARFEYTVIGDPVNEAARLTELAKLEDGHVLASA 500 LIPVLGSAEFGIGVSAGRAIAGHIGAQARFEYTVIGDPVNEAARLTELAKLE+GHVLASA Sbjct 421 LIPVLGSAEFGIGVSAGRAIAGHIGAQARFEYTVIGDPVNEAARLTELAKLEEGHVLASA 480 Query 501 IAVSGALDAEALCWDVGEVVELRGRAAPTQLARPMNLAAPEEVSSE 546 A+SGALDAEALCWDV EVVELRGR APTQLARP+NLA ++VS++ Sbjct 481 FAISGALDAEALCWDVAEVVELRGRTAPTQLARPLNLAVAQKVSTK 526 >gi|15827006|ref|NP_301269.1| hypothetical protein ML0201 [Mycobacterium leprae TN] gi|221229484|ref|YP_002502900.1| hypothetical protein MLBr_00201 [Mycobacterium leprae Br4923] gi|3097240|emb|CAA18817.1| putative membrane protein [Mycobacterium leprae] gi|13092553|emb|CAC29709.1| putative membrane protein [Mycobacterium leprae] gi|219932591|emb|CAR70294.1| putative membrane protein [Mycobacterium leprae Br4923] Length=530 Score = 867 bits (2239), Expect = 0.0, Method: Compositional matrix adjust. Identities = 453/530 (86%), Positives = 482/530 (91%), Gaps = 1/530 (0%) Query 21 MATTAA-LPRRIHAFVRWVVRTPWPLFSLSMLQSDIIGALFVLGFLRYGLPPQDNIQLQD 79 MAT AA LP RI AFVRW +RTPWPLFSLSMLQSDIIGALFVLGFLRYGLPPQD ++LQD Sbjct 1 MATQAAGLPGRIGAFVRWGIRTPWPLFSLSMLQSDIIGALFVLGFLRYGLPPQDRVELQD 60 Query 80 LPPVNLLIFVSTVIILFLAGAVVNLKLLMPVFRWQRRDNLLTEPDPAATELARSRALRMP 139 LP NL I +V++ F G VNLKLLMPVFRWQRRDN L E DPAATELARSRALRMP Sbjct 61 LPIRNLAISTLSVVVAFSTGFAVNLKLLMPVFRWQRRDNRLAEADPAATELARSRALRMP 120 Query 140 LYRTLISLAVWATGGGVFILASWSVAKHAAPVVAVATALGATATAIIGYLQSERVLRPVA 199 Y T+ISL W GG VFI+ASWS A+H+AP+VA+ATALGATATAIIGYLQSERVLRPVA Sbjct 121 FYHTIISLVTWGIGGAVFIIASWSAARHSAPIVALATALGATATAIIGYLQSERVLRPVA 180 Query 200 VAALRSGVPENVNAPGVILRLMLAWIPSTGVPLLAIVLAVAADKIALLHATPEALFNPIL 259 VAALRSGVPENV PGV LRLML W+PSTGVP+LAIVLAV ADKIALLHA PE LF+PIL Sbjct 181 VAALRSGVPENVKTPGVTLRLMLTWVPSTGVPVLAIVLAVVADKIALLHAVPEQLFSPIL 240 Query 260 MMALAALGIGSVSTLLVAMSIADPLRQLRWALSEVQRGNYNAHMQIYDASELGLLQAGFN 319 ++ALA L +G VST LVAMSIADPLRQLRWALSEVQRGNYNAHMQIYDASELGLLQAGFN Sbjct 241 LLALAVLVVGLVSTWLVAMSIADPLRQLRWALSEVQRGNYNAHMQIYDASELGLLQAGFN 300 Query 320 DMVRELSERQRLRDLFGRYVGEDVARRALERGTELGGQERDVAVLFVDLVGSTQLAATRP 379 DMVRELSERQRLRDLFGRYVGEDVARRALE GTELGGQERDVAVLFVDL+GSTQLA T+P Sbjct 301 DMVRELSERQRLRDLFGRYVGEDVARRALEHGTELGGQERDVAVLFVDLIGSTQLAETKP 360 Query 380 PAEVVQLLNEFFRVVVETVARHGGFVNKFQGDAALAIFGAPIEHPDGAGAALSAARELHD 439 P +VV LLNEFFRVVV+TV RHGGFVNKFQGDAALAIFGAPIEHPD AGAALSAARELHD Sbjct 361 PTKVVHLLNEFFRVVVDTVGRHGGFVNKFQGDAALAIFGAPIEHPDSAGAALSAARELHD 420 Query 440 ELIPVLGSAEFGIGVSAGRAIAGHIGAQARFEYTVIGDPVNEAARLTELAKLEDGHVLAS 499 EL+PVLGSAEFGIGVSAGRAIAGHIGAQARFEYTVIGDPVNEAARLTELAKLEDGHVLAS Sbjct 421 ELLPVLGSAEFGIGVSAGRAIAGHIGAQARFEYTVIGDPVNEAARLTELAKLEDGHVLAS 480 Query 500 AIAVSGALDAEALCWDVGEVVELRGRAAPTQLARPMNLAAPEEVSSEVRG 549 AIAVSGALDAEALCW+VGE+VELRGR APTQLARP+NLA PE+++SEV G Sbjct 481 AIAVSGALDAEALCWNVGEIVELRGRTAPTQLARPLNLAVPEQITSEVTG 530 >gi|342862018|ref|ZP_08718662.1| adenylate cyclase, family protein 3 [Mycobacterium colombiense CECT 3035] gi|342130558|gb|EGT83867.1| adenylate cyclase, family protein 3 [Mycobacterium colombiense CECT 3035] Length=524 Score = 858 bits (2216), Expect = 0.0, Method: Compositional matrix adjust. Identities = 436/521 (84%), Positives = 468/521 (90%), Gaps = 10/521 (1%) Query 39 VRTPWPLFSLSMLQSDIIGALFVLGFLRYGLPPQDNIQLQDLPPVNLLIFVSTVIILFLA 98 +RTPWPLFSLSMLQ+DIIGALFVLGFLRY LPP+D IQLQDLP +NL IF + ++++FL Sbjct 1 MRTPWPLFSLSMLQADIIGALFVLGFLRYALPPEDRIQLQDLPVLNLAIFATALVVVFLT 60 Query 99 GAVVNLKLLMPVFRWQRRDNLLTEPDPAATELARSRALRMPLYRTLISLAVWATGGGVFI 158 G V L+LLMPVFRWQRRDN+L E DPAATELARSRALRMP YRTLIS+ WA G VFI Sbjct 61 GLAVTLRLLMPVFRWQRRDNMLAEADPAATELARSRALRMPFYRTLISIVAWAIGSVVFI 120 Query 159 LASWSVAKHAAPVVAVATALGATATAIIGYLQSERVLRPVAVAALRSGVPENVNAPGVIL 218 +ASWSVA+ AAPVVAV+T LGA AT+IIGYLQSERVLRPVAVAALRSGVPENV APGVIL Sbjct 121 IASWSVARFAAPVVAVSTGLGAAATSIIGYLQSERVLRPVAVAALRSGVPENVKAPGVIL 180 Query 219 RLMLAWIPSTGVPLLAIVLAVAADKIALLHATPEALFNPILMMALAALGIGSVSTLLVAM 278 R +L W+ ST VP+LAIVLAV ADK +LLHATPE LF PIL++A AALGIG VSTLLVAM Sbjct 181 RQILTWMLSTAVPVLAIVLAVVADKTSLLHATPEKLFTPILLLACAALGIGLVSTLLVAM 240 Query 279 SIADPLRQLRWALSEVQRGNYNAHMQIYDASELGLLQAGFNDMVRELSERQRLRDLFGRY 338 SIADPLRQLRWALSEVQRGNYNAHMQIYDASELGLLQAGFNDMVR+LSERQRLRDLFGRY Sbjct 241 SIADPLRQLRWALSEVQRGNYNAHMQIYDASELGLLQAGFNDMVRDLSERQRLRDLFGRY 300 Query 339 VGEDVARRALERGTELGGQERDVAVLFVDLVGSTQLAATRPPAEVVQLLNEFFRVVVETV 398 VGEDVARRALERGTELGGQERDVAVLFVDLVGSTQLA+TRPPAEVV LLNEFFRVVVETV Sbjct 301 VGEDVARRALERGTELGGQERDVAVLFVDLVGSTQLASTRPPAEVVHLLNEFFRVVVETV 360 Query 399 ARHGGFVNKFQGDAALAIFGAPIEHPDGAGAALSAARELHDELIPVLGSAEFGIGVSAGR 458 +HGGFVNKFQGDAALAIFGAPIEHPD G AL+AARELHD L+PV+GSAEFGIGVS+GR Sbjct 361 GKHGGFVNKFQGDAALAIFGAPIEHPDSPGGALAAARELHDALLPVIGSAEFGIGVSSGR 420 Query 459 AIAGHIGAQARFEYTVIGDPVNEAARLTELAKLEDGHVLASAIAVSGALDAEALCWDVGE 518 AIAGHIGAQARFEYTVIGDPVNEAARLTELAKLE GHVLASAIAVSGALDAEALCWDVGE Sbjct 421 AIAGHIGAQARFEYTVIGDPVNEAARLTELAKLEPGHVLASAIAVSGALDAEALCWDVGE 480 Query 519 VVELRGRAAPTQLARPMNLA------AP----EEVSSEVRG 549 VVELRGR APTQLARP++LA AP EE+S E G Sbjct 481 VVELRGRRAPTQLARPVHLAGTPDSEAPRARAEEMSGETIG 521 >gi|254773488|ref|ZP_05215004.1| adenylate cyclase, family protein 3 [Mycobacterium avium subsp. avium ATCC 25291] Length=516 Score = 855 bits (2210), Expect = 0.0, Method: Compositional matrix adjust. Identities = 440/517 (86%), Positives = 472/517 (92%), Gaps = 6/517 (1%) Query 38 VVRTPWPLFSLSMLQSDIIGALFVLGFLRYGLPPQDNIQLQDLPPVNLLIFVSTVIILFL 97 +VRTPWPLF LSM+Q+DIIGALFVLGFLRY LPP+D IQLQDLP VNL +F +++++LFL Sbjct 1 MVRTPWPLFWLSMMQADIIGALFVLGFLRYALPPEDRIQLQDLPVVNLAVFATSLVVLFL 60 Query 98 AGAVVNLKLLMPVFRWQRRDNLLTEPDPAATELARSRALRMPLYRTLISLAVWATGGGVF 157 A +VVNL LLMPVFRWQRRDNLL E DPAATELAR RALRMP YRT+ S+ +W GG VF Sbjct 61 AASVVNLTLLMPVFRWQRRDNLLAESDPAATELARIRALRMPFYRTVTSMVIWCIGGVVF 120 Query 158 ILASWSVAKHAAPVVAVATALGATATAIIGYLQSERVLRPVAVAALRSGVPENVNAPGVI 217 I+ASWSVA+ AAPVVAVAT LGA ATAIIGYLQ ERVLRPVAVAALRSGVPENV APGVI Sbjct 121 IIASWSVARFAAPVVAVATGLGAAATAIIGYLQCERVLRPVAVAALRSGVPENVKAPGVI 180 Query 218 LRLMLAWIPSTGVPLLAIVLAVAADKIALLHATPEALFNPILMMALAALGIGSVSTLLVA 277 LR +L W+ ST VP+LAIVLAV ADK +LLHATPE LF PIL++A+AALGIG VSTLLVA Sbjct 181 LRQILTWMLSTAVPVLAIVLAVVADKTSLLHATPEKLFTPILLLAVAALGIGLVSTLLVA 240 Query 278 MSIADPLRQLRWALSEVQRGNYNAHMQIYDASELGLLQAGFNDMVRELSERQRLRDLFGR 337 MSIADPLRQLRWALSEVQRGNYNAHMQIYDASELGLLQAGFNDMVR+LSERQRLRDLFGR Sbjct 241 MSIADPLRQLRWALSEVQRGNYNAHMQIYDASELGLLQAGFNDMVRDLSERQRLRDLFGR 300 Query 338 YVGEDVARRALERGTELGGQERDVAVLFVDLVGSTQLAATRPPAEVVQLLNEFFRVVVET 397 YVGEDVARRALERGTELGGQERDVAVLFVDLVGSTQLAATRPPAEVV LLNEFFRVVVET Sbjct 301 YVGEDVARRALERGTELGGQERDVAVLFVDLVGSTQLAATRPPAEVVHLLNEFFRVVVET 360 Query 398 VARHGGFVNKFQGDAALAIFGAPIEHPDGAGAALSAARELHDELIPVLGSAEFGIGVSAG 457 V +HGGFVNKFQGDAALAIFGAPIEHPD +G AL+AARELHD L+PV+GSAEFGIGVSAG Sbjct 361 VGKHGGFVNKFQGDAALAIFGAPIEHPD-SGGALAAARELHDALLPVIGSAEFGIGVSAG 419 Query 458 RAIAGHIGAQARFEYTVIGDPVNEAARLTELAKLEDGHVLASAIAVSGALDAEALCWDVG 517 RAIAGHIGAQARFEYTVIGDPVNEAARLTELAKLE GHVLASAIAVSGALD+EALCWDVG Sbjct 420 RAIAGHIGAQARFEYTVIGDPVNEAARLTELAKLEPGHVLASAIAVSGALDSEALCWDVG 479 Query 518 EVVELRGRAAPTQLARPMNLA-----APEEVSSEVRG 549 EVVELRGR APTQLARP+ LA AP+EVSSEV G Sbjct 480 EVVELRGRTAPTQLARPVKLATPEEVAPQEVSSEVSG 516 >gi|254821837|ref|ZP_05226838.1| adenylate cyclase, family protein 3 [Mycobacterium intracellulare ATCC 13950] Length=517 Score = 845 bits (2184), Expect = 0.0, Method: Compositional matrix adjust. Identities = 445/517 (87%), Positives = 476/517 (93%), Gaps = 5/517 (0%) Query 38 VVRTPWPLFSLSMLQSDIIGALFVLGFLRYGLPPQDNIQLQDLPPVNLLIFVSTVIILFL 97 +VRTPWPLF+LSMLQ+DIIGALFVLGFLRYGLPPQD I+LQDLP +NL IF S++++LFL Sbjct 1 MVRTPWPLFALSMLQADIIGALFVLGFLRYGLPPQDRIELQDLPTLNLAIFSSSLVVLFL 60 Query 98 AGAVVNLKLLMPVFRWQRRDNLLTEPDPAATELARSRALRMPLYRTLISLAVWATGGGVF 157 G VVNLKLLMPVFRWQRRDN+L E DP ATELARSRALRMP YRTL ++A W GG VF Sbjct 61 VGVVVNLKLLMPVFRWQRRDNMLAETDPVATELARSRALRMPYYRTLSTVAYWCIGGVVF 120 Query 158 ILASWSVAKHAAPVVAVATALGATATAIIGYLQSERVLRPVAVAALRSGVPENVNAPGVI 217 I+ASWSVAK AAPVV+VATALGA ATAIIGYLQSERVLRPVAVAALRSGVPENV APGVI Sbjct 121 IVASWSVAKFAAPVVSVATALGAAATAIIGYLQSERVLRPVAVAALRSGVPENVKAPGVI 180 Query 218 LRLMLAWIPSTGVPLLAIVLAVAADKIALLHATPEALFNPILMMALAALGIGSVSTLLVA 277 LR +L W+ ST VPL+AIVLAV ADK +LLHA PE+LFNPIL++AL ALG+G +STLLVA Sbjct 181 LRQILTWMLSTAVPLMAIVLAVVADKASLLHAAPESLFNPILLLALTALGVGLISTLLVA 240 Query 278 MSIADPLRQLRWALSEVQRGNYNAHMQIYDASELGLLQAGFNDMVRELSERQRLRDLFGR 337 MSIADPLRQLRWALSEVQRGNYNAHMQIYDASELGLLQAGFNDMVR+LSERQRLRDLFGR Sbjct 241 MSIADPLRQLRWALSEVQRGNYNAHMQIYDASELGLLQAGFNDMVRDLSERQRLRDLFGR 300 Query 338 YVGEDVARRALERGTELGGQERDVAVLFVDLVGSTQLAATRPPAEVVQLLNEFFRVVVET 397 YVGEDVARRALERGTELGGQERDVAVLFVDLVGSTQLA+TRPPAEVV LLNEFFRVVVET Sbjct 301 YVGEDVARRALERGTELGGQERDVAVLFVDLVGSTQLASTRPPAEVVHLLNEFFRVVVET 360 Query 398 VARHGGFVNKFQGDAALAIFGAPIEHPDGAGAALSAARELHDELIPVLGSAEFGIGVSAG 457 V RHGGFVNKFQGDAALAIFGAPIEHPD G AL+AARELHDEL+PV+GSAEFGIGVS+G Sbjct 361 VGRHGGFVNKFQGDAALAIFGAPIEHPDSPGGALAAARELHDELLPVIGSAEFGIGVSSG 420 Query 458 RAIAGHIGAQARFEYTVIGDPVNEAARLTELAKLEDGHVLASAIAVSGALDAEALCWDVG 517 RAIAGHIGAQARFEYTVIGDPVNEAARLTELAKLE GHVLASAIAVSGALDAEALCWDVG Sbjct 421 RAIAGHIGAQARFEYTVIGDPVNEAARLTELAKLEPGHVLASAIAVSGALDAEALCWDVG 480 Query 518 EVVELRGRAAPTQLARPMNLAAPE-----EVSSEVRG 549 EVVELRGR APTQLARP+ LAAPE EVSS+ RG Sbjct 481 EVVELRGRRAPTQLARPVKLAAPEEVAPQEVSSDARG 517 >gi|145221987|ref|YP_001132665.1| putative adenylate/guanylate cyclase [Mycobacterium gilvum PYR-GCK] gi|315446273|ref|YP_004079152.1| family 3 adenylate cyclase [Mycobacterium sp. Spyr1] gi|145214473|gb|ABP43877.1| putative adenylate/guanylate cyclase [Mycobacterium gilvum PYR-GCK] gi|315264576|gb|ADU01318.1| family 3 adenylate cyclase [Mycobacterium sp. Spyr1] Length=536 Score = 792 bits (2046), Expect = 0.0, Method: Compositional matrix adjust. Identities = 400/518 (78%), Positives = 443/518 (86%), Gaps = 0/518 (0%) Query 30 RIHAFVRWVVRTPWPLFSLSMLQSDIIGALFVLGFLRYGLPPQDNIQLQDLPPVNLLIFV 89 RI AFVRWV RTPWP+F+L MLQ+DIIGAL VLGFLR+GLPP+D IQLQDLP NL IF+ Sbjct 10 RISAFVRWVARTPWPVFTLGMLQADIIGALLVLGFLRFGLPPEDRIQLQDLPAYNLAIFL 69 Query 90 STVIILFLAGAVVNLKLLMPVFRWQRRDNLLTEPDPAATELARSRALRMPLYRTLISLAV 149 + + F + + L++L+PV RWQRRD LL + DP+ TE+AR RAL+MP YR+LIS Sbjct 70 GYLFVSFTVASYLTLRMLIPVMRWQRRDMLLGDRDPSDTEVARMRALKMPFYRSLISATN 129 Query 150 WATGGGVFILASWSVAKHAAPVVAVATALGATATAIIGYLQSERVLRPVAVAALRSGVPE 209 W G VFI+ASW VA +APVVAVAT LGATATAIIGYLQSERVLRPVAVAALR GVPE Sbjct 130 WLLGSVVFIVASWPVASKSAPVVAVATGLGATATAIIGYLQSERVLRPVAVAALRGGVPE 189 Query 210 NVNAPGVILRLMLAWIPSTGVPLLAIVLAVAADKIALLHATPEALFNPILMMALAALGIG 269 N APGVILR +L W+ STGVP+LAIVLA+ A K +L A + L IL++A+ AL IG Sbjct 190 NFRAPGVILRQVLTWVLSTGVPVLAIVLALVASKFEVLTAPADRLITTILLLAIVALIIG 249 Query 270 SVSTLLVAMSIADPLRQLRWALSEVQRGNYNAHMQIYDASELGLLQAGFNDMVRELSERQ 329 ST+LVAMSIADPLRQLRWAL EVQRGNYNAHMQIYDASELGLLQAGFNDMVR+L+ERQ Sbjct 250 LSSTVLVAMSIADPLRQLRWALGEVQRGNYNAHMQIYDASELGLLQAGFNDMVRDLAERQ 309 Query 330 RLRDLFGRYVGEDVARRALERGTELGGQERDVAVLFVDLVGSTQLAATRPPAEVVQLLNE 389 RLRDLFGRYVGEDVARRALERGTELGGQERDVAVLFVDLVGST LAAT P +EVV LLNE Sbjct 310 RLRDLFGRYVGEDVARRALERGTELGGQERDVAVLFVDLVGSTHLAATIPASEVVSLLNE 369 Query 390 FFRVVVETVARHGGFVNKFQGDAALAIFGAPIEHPDGAGAALSAARELHDELIPVLGSAE 449 FFRVVV+TV RHGGFVNKFQGDAALAIFGAPIEHPD +GAAL+A+RELHDELI VLG E Sbjct 370 FFRVVVDTVNRHGGFVNKFQGDAALAIFGAPIEHPDASGAALAASRELHDELINVLGETE 429 Query 450 FGIGVSAGRAIAGHIGAQARFEYTVIGDPVNEAARLTELAKLEDGHVLASAIAVSGALDA 509 FGIGVSAGRAIAGHIGAQARFEYTVIGDPVNEAARLTELAKLE GHVLAS++AV+ ALDA Sbjct 430 FGIGVSAGRAIAGHIGAQARFEYTVIGDPVNEAARLTELAKLEPGHVLASSLAVADALDA 489 Query 510 EALCWDVGEVVELRGRAAPTQLARPMNLAAPEEVSSEV 547 EALCW+VGEVVELRGR APTQLARP+NL P V +V Sbjct 490 EALCWNVGEVVELRGRTAPTQLARPVNLIRPPRVEEKV 527 >gi|118470462|ref|YP_890374.1| adenylate cyclase, family protein 3 [Mycobacterium smegmatis str. MC2 155] gi|118171749|gb|ABK72645.1| adenylate cyclase, family protein 3 [Mycobacterium smegmatis str. MC2 155] Length=563 Score = 792 bits (2046), Expect = 0.0, Method: Compositional matrix adjust. Identities = 409/529 (78%), Positives = 460/529 (87%), Gaps = 2/529 (0%) Query 23 TTAALP-RRIHAFVRWVVRTPWPLFSLSMLQSDIIGALFVLGFLRYGLPPQDNIQLQDLP 81 TT +P RI AF RWV RTPWP+F+L MLQ+DIIGALFVLGFLR+GLPP+D IQLQDLP Sbjct 2 TTEPIPIARIGAFARWVARTPWPVFTLGMLQADIIGALFVLGFLRFGLPPEDRIQLQDLP 61 Query 82 PVNLLIFVSTVIILFLAGAVVNLKLLMPVFRWQRRDNLLTEPDPAATELARSRALRMPLY 141 NL IF++ + + F GA + L+LL+PV RWQRR+ +L+E DP TELAR+RAL+MP Y Sbjct 62 AFNLAIFLAYLFVSFTVGAYLALRLLIPVIRWQRRETVLSEGDPGITELARARALKMPFY 121 Query 142 RTLISLAVWATGGGVFILASWSVAKHAAPVVAVATALGATATAIIGYLQSERVLRPVAVA 201 RTLIS+ W G VFI+ASW VA H+APVVAVATALGATATAIIGYLQSERVLRPVAVA Sbjct 122 RTLISVTNWCLGSIVFIVASWPVASHSAPVVAVATALGATATAIIGYLQSERVLRPVAVA 181 Query 202 ALRSGVPENVNAPGVILRLMLAWIPSTGVPLLAIVLAVAADKIALLHATPEALFNPILMM 261 ALR GVPEN APGVILR +L W+ STGVPLLAI+LA+ A K ++L A+ + L PIL++ Sbjct 182 ALRGGVPENFRAPGVILRQVLTWVLSTGVPLLAIILALVASKFSILTASADRLNTPILLL 241 Query 262 ALAALGIGSVSTLLVAMSIADPLRQLRWALSEVQRGNYNAHMQIYDASELGLLQAGFNDM 321 A+AAL IG ST+LVAMSIADPLRQLRWAL EVQRGNYNAHMQIYDASELGLLQAGFNDM Sbjct 242 AVAALVIGMSSTVLVAMSIADPLRQLRWALGEVQRGNYNAHMQIYDASELGLLQAGFNDM 301 Query 322 VRELSERQRLRDLFGRYVGEDVARRALERGTELGGQERDVAVLFVDLVGSTQLAATRPPA 381 VR+L+ERQRLRDLFGRYVGEDVARRALERGTELGGQERDVAVLFVDLVGST LA+T P A Sbjct 302 VRDLAERQRLRDLFGRYVGEDVARRALERGTELGGQERDVAVLFVDLVGSTHLASTIPAA 361 Query 382 EVVQLLNEFFRVVVETVARHGGFVNKFQGDAALAIFGAPIEHPDGAGAALSAARELHDEL 441 +VV LLNEFFRV+V+TV +HGGFVNKFQGDAALAIFGAPIEHPD +G AL+A+RELHDEL Sbjct 362 DVVNLLNEFFRVIVDTVNKHGGFVNKFQGDAALAIFGAPIEHPDASGGALAASRELHDEL 421 Query 442 IPVLGS-AEFGIGVSAGRAIAGHIGAQARFEYTVIGDPVNEAARLTELAKLEDGHVLASA 500 I VLG+ EFGIGVSAGRAIAGHIGA+ARFEYTVIGDPVNEAARLTELAKLE+GHVLASA Sbjct 422 IKVLGTETEFGIGVSAGRAIAGHIGAKARFEYTVIGDPVNEAARLTELAKLEEGHVLASA 481 Query 501 IAVSGALDAEALCWDVGEVVELRGRAAPTQLARPMNLAAPEEVSSEVRG 549 IAVSGALD+EALCWDVGE+VELRGR PTQLARP+NLA PE++ G Sbjct 482 IAVSGALDSEALCWDVGEIVELRGRTVPTQLARPINLARPEDLDGSANG 530 >gi|108801758|ref|YP_641955.1| adenylate/guanylate cyclase [Mycobacterium sp. MCS] gi|119870909|ref|YP_940861.1| putative adenylate/guanylate cyclase [Mycobacterium sp. KMS] gi|126437745|ref|YP_001073436.1| putative adenylate/guanylate cyclase [Mycobacterium sp. JLS] gi|108772177|gb|ABG10899.1| adenylate/guanylate cyclase [Mycobacterium sp. MCS] gi|119696998|gb|ABL94071.1| putative adenylate/guanylate cyclase [Mycobacterium sp. KMS] gi|126237545|gb|ABO00946.1| putative adenylate/guanylate cyclase [Mycobacterium sp. JLS] Length=528 Score = 790 bits (2041), Expect = 0.0, Method: Compositional matrix adjust. Identities = 411/528 (78%), Positives = 456/528 (87%), Gaps = 0/528 (0%) Query 21 MATTAALPRRIHAFVRWVVRTPWPLFSLSMLQSDIIGALFVLGFLRYGLPPQDNIQLQDL 80 MA+ A RI AFVRWV RTPWP+F+L MLQ+DIIGALFVLGFLR+GLPP+D +QLQDL Sbjct 1 MASEAIPIGRISAFVRWVARTPWPVFTLGMLQADIIGALFVLGFLRFGLPPEDRVQLQDL 60 Query 81 PPVNLLIFVSTVIILFLAGAVVNLKLLMPVFRWQRRDNLLTEPDPAATELARSRALRMPL 140 P NL IF+ + + F GA ++L+LL+PV RWQRRD LL + D + T+LAR+RALRMP Sbjct 61 PAFNLAIFLGYLFVSFTVGAYLSLRLLIPVIRWQRRDTLLADGDTSTTDLARARALRMPF 120 Query 141 YRTLISLAVWATGGGVFILASWSVAKHAAPVVAVATALGATATAIIGYLQSERVLRPVAV 200 YRT+IS+A W G VFI+ASW VA +APVVAVATALGATATAIIGYLQSERVLRPVAV Sbjct 121 YRTVISVANWCLGSIVFIVASWPVASKSAPVVAVATALGATATAIIGYLQSERVLRPVAV 180 Query 201 AALRSGVPENVNAPGVILRLMLAWIPSTGVPLLAIVLAVAADKIALLHATPEALFNPILM 260 AALR GVPEN APGV+LR +L W+ STGVP+LAIVLA+ A + +L A + L PIL+ Sbjct 181 AALRGGVPENFRAPGVVLRQVLTWVLSTGVPVLAIVLALVASQFDILEAPADRLTMPILL 240 Query 261 MALAALGIGSVSTLLVAMSIADPLRQLRWALSEVQRGNYNAHMQIYDASELGLLQAGFND 320 +A+AAL IG T+LVAMSIADPLRQLRWAL EVQRGNYNAHMQIYDASELGLLQAGFND Sbjct 241 LAIAALVIGLAGTVLVAMSIADPLRQLRWALGEVQRGNYNAHMQIYDASELGLLQAGFND 300 Query 321 MVRELSERQRLRDLFGRYVGEDVARRALERGTELGGQERDVAVLFVDLVGSTQLAATRPP 380 MVR+LSERQRLRDLFGRYVGEDVARRALERGTELGGQERDVAVLFVDLVGSTQLA+T P Sbjct 301 MVRDLSERQRLRDLFGRYVGEDVARRALERGTELGGQERDVAVLFVDLVGSTQLASTIPA 360 Query 381 AEVVQLLNEFFRVVVETVARHGGFVNKFQGDAALAIFGAPIEHPDGAGAALSAARELHDE 440 A+VV LLN+FFRVVV+TV RHGGFVNKFQGDAALAIFGAPIEHPD GAAL+A+RELHDE Sbjct 361 ADVVNLLNDFFRVVVDTVNRHGGFVNKFQGDAALAIFGAPIEHPDACGAALAASRELHDE 420 Query 441 LIPVLGSAEFGIGVSAGRAIAGHIGAQARFEYTVIGDPVNEAARLTELAKLEDGHVLASA 500 LI VLG EFGIGVSAGRAIAGHIGAQARFEYTVIGDPVNEAARLTELAKLE GHVLASA Sbjct 421 LIKVLGQTEFGIGVSAGRAIAGHIGAQARFEYTVIGDPVNEAARLTELAKLEPGHVLASA 480 Query 501 IAVSGALDAEALCWDVGEVVELRGRAAPTQLARPMNLAAPEEVSSEVR 548 IAVSGALDAEALCW+VGE VELRGR APTQLARP+NL +P E+S R Sbjct 481 IAVSGALDAEALCWNVGETVELRGRIAPTQLARPVNLMSPREISDLSR 528 >gi|120406343|ref|YP_956172.1| putative adenylate/guanylate cyclase [Mycobacterium vanbaalenii PYR-1] gi|119959161|gb|ABM16166.1| putative adenylate/guanylate cyclase [Mycobacterium vanbaalenii PYR-1] Length=532 Score = 783 bits (2022), Expect = 0.0, Method: Compositional matrix adjust. Identities = 406/518 (79%), Positives = 451/518 (88%), Gaps = 0/518 (0%) Query 30 RIHAFVRWVVRTPWPLFSLSMLQSDIIGALFVLGFLRYGLPPQDNIQLQDLPPVNLLIFV 89 RI AFVRWV RTPWP+F+L MLQ+DIIGAL VLGFLR+GLPP+D IQLQDLP NL IF+ Sbjct 10 RISAFVRWVARTPWPVFTLGMLQADIIGALLVLGFLRFGLPPEDRIQLQDLPAYNLAIFL 69 Query 90 STVIILFLAGAVVNLKLLMPVFRWQRRDNLLTEPDPAATELARSRALRMPLYRTLISLAV 149 + I F + V L++L+PV RWQRR+ LL + DPA TE+AR RAL+MP YR+LIS Sbjct 70 GYLFISFTVASYVTLRMLIPVMRWQRREMLLGDRDPAETEVARMRALKMPFYRSLISATN 129 Query 150 WATGGGVFILASWSVAKHAAPVVAVATALGATATAIIGYLQSERVLRPVAVAALRSGVPE 209 W G VFI+ASW VA +APVVAVATALGATATAIIGYLQSERVLRPVAVAALR GVPE Sbjct 130 WLLGSVVFIVASWPVASKSAPVVAVATALGATATAIIGYLQSERVLRPVAVAALRGGVPE 189 Query 210 NVNAPGVILRLMLAWIPSTGVPLLAIVLAVAADKIALLHATPEALFNPILMMALAALGIG 269 N APGVILR +L+W+ STGVP+LAI+LA+ A K+ +L A + L IL++++ AL IG Sbjct 190 NFRAPGVILRQVLSWVLSTGVPVLAILLALIASKLEVLTAPADRLITTILLLSIVALVIG 249 Query 270 SVSTLLVAMSIADPLRQLRWALSEVQRGNYNAHMQIYDASELGLLQAGFNDMVRELSERQ 329 ST+LVAMSIADPLRQLRWAL EVQRGNYNAHMQIYDASELGLLQAGFNDMVR+L+ERQ Sbjct 250 LSSTVLVAMSIADPLRQLRWALGEVQRGNYNAHMQIYDASELGLLQAGFNDMVRDLAERQ 309 Query 330 RLRDLFGRYVGEDVARRALERGTELGGQERDVAVLFVDLVGSTQLAATRPPAEVVQLLNE 389 RLRDLFGRYVGEDVARRALERGTELGGQERDVAVLFVDLVGST LAATRP AEVV LLNE Sbjct 310 RLRDLFGRYVGEDVARRALERGTELGGQERDVAVLFVDLVGSTHLAATRPAAEVVNLLNE 369 Query 390 FFRVVVETVARHGGFVNKFQGDAALAIFGAPIEHPDGAGAALSAARELHDELIPVLGSAE 449 FFRVVV+TV RHGGFVNKFQGDAALAIFGAPIEHPD +GAAL+A+RELHDELI VLG + Sbjct 370 FFRVVVDTVNRHGGFVNKFQGDAALAIFGAPIEHPDASGAALAASRELHDELIRVLGETD 429 Query 450 FGIGVSAGRAIAGHIGAQARFEYTVIGDPVNEAARLTELAKLEDGHVLASAIAVSGALDA 509 FGIGVSAGRAIAGHIGAQARFEYTVIGDPVNEAARLTELAKLE GHVLASAIAV+ ALDA Sbjct 430 FGIGVSAGRAIAGHIGAQARFEYTVIGDPVNEAARLTELAKLEPGHVLASAIAVADALDA 489 Query 510 EALCWDVGEVVELRGRAAPTQLARPMNLAAPEEVSSEV 547 EALCWDVGE+VELRGR APTQLARP+NL +P++VS EV Sbjct 490 EALCWDVGEIVELRGRTAPTQLARPVNLVSPDDVSQEV 527 >gi|289748159|ref|ZP_06507537.1| transmembrane protein [Mycobacterium tuberculosis T92] gi|289688746|gb|EFD56175.1| transmembrane protein [Mycobacterium tuberculosis T92] Length=403 Score = 782 bits (2020), Expect = 0.0, Method: Compositional matrix adjust. Identities = 399/403 (99%), Positives = 401/403 (99%), Gaps = 0/403 (0%) Query 147 LAVWATGGGVFILASWSVAKHAAPVVAVATALGATATAIIGYLQSERVLRPVAVAALRSG 206 + VWATGGGVFILASWSVAKHAAPVVAVA+ALGATATA IGYLQSERVLRPVAVAALRSG Sbjct 1 MMVWATGGGVFILASWSVAKHAAPVVAVASALGATATASIGYLQSERVLRPVAVAALRSG 60 Query 207 VPENVNAPGVILRLMLAWIPSTGVPLLAIVLAVAADKIALLHATPEALFNPILMMALAAL 266 VPENVNAPGVILRLMLAWIPSTGVPLLAIVLAVAADKIALLHATPEALFNPILMMALAAL Sbjct 61 VPENVNAPGVILRLMLAWIPSTGVPLLAIVLAVAADKIALLHATPEALFNPILMMALAAL 120 Query 267 GIGSVSTLLVAMSIADPLRQLRWALSEVQRGNYNAHMQIYDASELGLLQAGFNDMVRELS 326 GIGSVSTLLVAMSIADPLRQLRWALSEVQRGNYNAHMQIYDASELGLLQAGFNDMVRELS Sbjct 121 GIGSVSTLLVAMSIADPLRQLRWALSEVQRGNYNAHMQIYDASELGLLQAGFNDMVRELS 180 Query 327 ERQRLRDLFGRYVGEDVARRALERGTELGGQERDVAVLFVDLVGSTQLAATRPPAEVVQL 386 ERQRLRDLFGRYVGEDVARRALERGTELGGQERDVAVLFVDLVGSTQLAATRPPAEVVQL Sbjct 181 ERQRLRDLFGRYVGEDVARRALERGTELGGQERDVAVLFVDLVGSTQLAATRPPAEVVQL 240 Query 387 LNEFFRVVVETVARHGGFVNKFQGDAALAIFGAPIEHPDGAGAALSAARELHDELIPVLG 446 LNEFFRVVVETVARHGGFVNKFQGDAALAIFGAPIEHPDGAGAALSAARELHDELIPVLG Sbjct 241 LNEFFRVVVETVARHGGFVNKFQGDAALAIFGAPIEHPDGAGAALSAARELHDELIPVLG 300 Query 447 SAEFGIGVSAGRAIAGHIGAQARFEYTVIGDPVNEAARLTELAKLEDGHVLASAIAVSGA 506 SAEFGIGVSAGRAIAGHIGAQARFEYTVIGDPVNEAARLTELAKLEDGHVLASAIAVSGA Sbjct 301 SAEFGIGVSAGRAIAGHIGAQARFEYTVIGDPVNEAARLTELAKLEDGHVLASAIAVSGA 360 Query 507 LDAEALCWDVGEVVELRGRAAPTQLARPMNLAAPEEVSSEVRG 549 LDAEALCWDVGEVVELRGRAAPTQLARPMNLAAPEEVSSEVRG Sbjct 361 LDAEALCWDVGEVVELRGRAAPTQLARPMNLAAPEEVSSEVRG 403 >gi|339296457|gb|AEJ48568.1| conserved transmembrane protein [Mycobacterium tuberculosis CCDC5079] Length=423 Score = 780 bits (2015), Expect = 0.0, Method: Compositional matrix adjust. Identities = 399/399 (100%), Positives = 399/399 (100%), Gaps = 0/399 (0%) Query 108 MPVFRWQRRDNLLTEPDPAATELARSRALRMPLYRTLISLAVWATGGGVFILASWSVAKH 167 MPVFRWQRRDNLLTEPDPAATELARSRALRMPLYRTLISLAVWATGGGVFILASWSVAKH Sbjct 1 MPVFRWQRRDNLLTEPDPAATELARSRALRMPLYRTLISLAVWATGGGVFILASWSVAKH 60 Query 168 AAPVVAVATALGATATAIIGYLQSERVLRPVAVAALRSGVPENVNAPGVILRLMLAWIPS 227 AAPVVAVATALGATATAIIGYLQSERVLRPVAVAALRSGVPENVNAPGVILRLMLAWIPS Sbjct 61 AAPVVAVATALGATATAIIGYLQSERVLRPVAVAALRSGVPENVNAPGVILRLMLAWIPS 120 Query 228 TGVPLLAIVLAVAADKIALLHATPEALFNPILMMALAALGIGSVSTLLVAMSIADPLRQL 287 TGVPLLAIVLAVAADKIALLHATPEALFNPILMMALAALGIGSVSTLLVAMSIADPLRQL Sbjct 121 TGVPLLAIVLAVAADKIALLHATPEALFNPILMMALAALGIGSVSTLLVAMSIADPLRQL 180 Query 288 RWALSEVQRGNYNAHMQIYDASELGLLQAGFNDMVRELSERQRLRDLFGRYVGEDVARRA 347 RWALSEVQRGNYNAHMQIYDASELGLLQAGFNDMVRELSERQRLRDLFGRYVGEDVARRA Sbjct 181 RWALSEVQRGNYNAHMQIYDASELGLLQAGFNDMVRELSERQRLRDLFGRYVGEDVARRA 240 Query 348 LERGTELGGQERDVAVLFVDLVGSTQLAATRPPAEVVQLLNEFFRVVVETVARHGGFVNK 407 LERGTELGGQERDVAVLFVDLVGSTQLAATRPPAEVVQLLNEFFRVVVETVARHGGFVNK Sbjct 241 LERGTELGGQERDVAVLFVDLVGSTQLAATRPPAEVVQLLNEFFRVVVETVARHGGFVNK 300 Query 408 FQGDAALAIFGAPIEHPDGAGAALSAARELHDELIPVLGSAEFGIGVSAGRAIAGHIGAQ 467 FQGDAALAIFGAPIEHPDGAGAALSAARELHDELIPVLGSAEFGIGVSAGRAIAGHIGAQ Sbjct 301 FQGDAALAIFGAPIEHPDGAGAALSAARELHDELIPVLGSAEFGIGVSAGRAIAGHIGAQ 360 Query 468 ARFEYTVIGDPVNEAARLTELAKLEDGHVLASAIAVSGA 506 ARFEYTVIGDPVNEAARLTELAKLEDGHVLASAIAVSGA Sbjct 361 ARFEYTVIGDPVNEAARLTELAKLEDGHVLASAIAVSGA 399 >gi|333992570|ref|YP_004525184.1| adenylate cyclase [Mycobacterium sp. JDM601] gi|333488538|gb|AEF37930.1| adenylate cyclase [Mycobacterium sp. JDM601] Length=533 Score = 768 bits (1982), Expect = 0.0, Method: Compositional matrix adjust. Identities = 407/524 (78%), Positives = 451/524 (87%), Gaps = 4/524 (0%) Query 30 RIHAFVRWVVRTPWPLFSLSMLQSDIIGALFVLGFLRYGLPPQDNIQLQDLPPVNLLIFV 89 RI FVRWVVRTPWP+F+LSMLQ+DIIG+LFV GFLR+GLP +D I LQDLP VNL++F Sbjct 4 RISRFVRWVVRTPWPVFTLSMLQADIIGSLFVFGFLRFGLPIEDRINLQDLPRVNLVVFA 63 Query 90 STVIILFLAGAVVNLKLLMPVFRWQRRDNLLTEPD----PAATELARSRALRMPLYRTLI 145 T+ LF+ G ++ LLMPVFRWQRR+ +L EPD PA TELARSRALRMP YR+LI Sbjct 64 VTLWCLFVLGFTISTSLLMPVFRWQRREAMLAEPDTEADPADTELARSRALRMPFYRSLI 123 Query 146 SLAVWATGGGVFILASWSVAKHAAPVVAVATALGATATAIIGYLQSERVLRPVAVAALRS 205 S++ W GG VF+ ASW V PVV ATALGA ATAIIGYLQSERVLRPVAVAALR Sbjct 124 SISYWTVGGVVFVAASWPVTYDVLPVVVTATALGAAATAIIGYLQSERVLRPVAVAALRG 183 Query 206 GVPENVNAPGVILRLMLAWIPSTGVPLLAIVLAVAADKIALLHATPEALFNPILMMALAA 265 GVPEN+ APGV+LR +L W+ STGVPLLAIVL+V A K +LL A+ + LF PIL MALAA Sbjct 184 GVPENLRAPGVLLRQLLTWLLSTGVPLLAIVLSVVAAKTSLLDASADKLFTPILFMALAA 243 Query 266 LGIGSVSTLLVAMSIADPLRQLRWALSEVQRGNYNAHMQIYDASELGLLQAGFNDMVREL 325 L IG T LV+MSIADPLRQLRWAL EVQRGNYNAHMQIYDASELGLLQAGFNDMVR+L Sbjct 244 LVIGLAGTALVSMSIADPLRQLRWALGEVQRGNYNAHMQIYDASELGLLQAGFNDMVRDL 303 Query 326 SERQRLRDLFGRYVGEDVARRALERGTELGGQERDVAVLFVDLVGSTQLAATRPPAEVVQ 385 +ERQRLRDLFGRYVGEDVARRALERGTELGGQERDVAVLFVDLVGST+LA+TRPP+EVV Sbjct 304 AERQRLRDLFGRYVGEDVARRALERGTELGGQERDVAVLFVDLVGSTELASTRPPSEVVN 363 Query 386 LLNEFFRVVVETVARHGGFVNKFQGDAALAIFGAPIEHPDGAGAALSAARELHDELIPVL 445 LLNEFFRVVVE V RHGGFVNKFQGDAALAIFGAPIEHPD AAL+AARELHD L+PVL Sbjct 364 LLNEFFRVVVEAVGRHGGFVNKFQGDAALAIFGAPIEHPDACSAALAAARELHDGLLPVL 423 Query 446 GSAEFGIGVSAGRAIAGHIGAQARFEYTVIGDPVNEAARLTELAKLEDGHVLASAIAVSG 505 GS EFGIGVSAGRAIAGHIGA+ARFEYTVIGDPVNEAARLTELAKLE+GHVLASA+AVSG Sbjct 424 GSEEFGIGVSAGRAIAGHIGARARFEYTVIGDPVNEAARLTELAKLEEGHVLASAVAVSG 483 Query 506 ALDAEALCWDVGEVVELRGRAAPTQLARPMNLAAPEEVSSEVRG 549 A+D+EALCW+VGE+VELRGRA TQLARP+ +A + VSSE G Sbjct 484 AVDSEALCWEVGEIVELRGRAGSTQLARPLKIAGTDAVSSENAG 527 >gi|169627594|ref|YP_001701243.1| putative adenylate cyclase [Mycobacterium abscessus ATCC 19977] gi|169239561|emb|CAM60589.1| Putative adenylate cyclase [Mycobacterium abscessus] Length=519 Score = 661 bits (1706), Expect = 0.0, Method: Compositional matrix adjust. Identities = 352/509 (70%), Positives = 404/509 (80%), Gaps = 7/509 (1%) Query 30 RIHAFVRWVVRTPWPLFSLSMLQSDIIGALFVLGFLRYGLPPQDNIQLQDLPPVNLLIFV 89 R + RWV+RTPWPLF + + QS+++GALFVLGFLR+GLPP D ++L +L P L+I Sbjct 15 RAARYSRWVMRTPWPLFIMGIAQSNLVGALFVLGFLRFGLPPSDRVELTELGPTRLIILG 74 Query 90 STVIILFLAGAVVNLKLLMPVFRWQRRDNLLTEPD--PAATELARSRALRMPLYRTLISL 147 ++ ILF+ GA+V+ LL+PV RWQ R PD +E R RAL+MP YRT+IS+ Sbjct 75 FSLFILFVVGAIVSTYLLLPVLRWQYRS-----PDFESEGSEAVRVRALQMPFYRTVISV 129 Query 148 AVWATGGGVFILASWSVAKHAAPVVAVATALGATATAIIGYLQSERVLRPVAVAALRSGV 207 A W GG +F+ +WS + V A AT LGAT T+IIGYLQSERVLRPVA+ ALR GV Sbjct 130 ATWLVGGAIFVAVTWSSTHSSVLVAAFATVLGATTTSIIGYLQSERVLRPVAIQALRRGV 189 Query 208 PENVNAPGVILRLMLAWIPSTGVPLLAIVLAVAADKIALLHATPEALFNPILMMALAALG 267 PENV APGVI+R +L W STGVP+LAIVL V + L + + L IL++A+ AL Sbjct 190 PENVTAPGVIVRQILTWALSTGVPILAIVLTVVGQRAGYLKSNADNLTGSILILAIIALA 249 Query 268 IGSVSTLLVAMSIADPLRQLRWALSEVQRGNYNAHMQIYDASELGLLQAGFNDMVRELSE 327 IG + TLLVA SIADPLRQLRWALSEVQRGNYNAH+ IYDASELGLLQAGFNDMVR+L E Sbjct 250 IGLMGTLLVATSIADPLRQLRWALSEVQRGNYNAHVPIYDASELGLLQAGFNDMVRDLGE 309 Query 328 RQRLRDLFGRYVGEDVARRALERGTELGGQERDVAVLFVDLVGSTQLAATRPPAEVVQLL 387 RQRLRDLFGRYVGEDVARRALE GTELGGQER VAVLFVDLVGSTQLA+TR PA VV++L Sbjct 310 RQRLRDLFGRYVGEDVARRALEYGTELGGQERSVAVLFVDLVGSTQLASTRGPAVVVRVL 369 Query 388 NEFFRVVVETVARHGGFVNKFQGDAALAIFGAPIEHPDGAGAALSAARELHDELIPVLGS 447 NEFFRV+V+TV +HGGFVNKFQGDAALAIFGAPI+HPDGA AAL+AAREL EL VLGS Sbjct 370 NEFFRVIVDTVNKHGGFVNKFQGDAALAIFGAPIDHPDGAAAALAAARELSGELTNVLGS 429 Query 448 AEFGIGVSAGRAIAGHIGAQARFEYTVIGDPVNEAARLTELAKLEDGHVLASAIAVSGAL 507 +FGIGVSAGRAIAGHIGAQARFEYTVIGDPVNEAARLTELAK E G+VLASA AV A Sbjct 430 NDFGIGVSAGRAIAGHIGAQARFEYTVIGDPVNEAARLTELAKNEPGNVLASASAVMEAR 489 Query 508 DAEALCWDVGEVVELRGRAAPTQLARPMN 536 D EAL WDVGE VELRGR TQ+ARP + Sbjct 490 DEEALRWDVGETVELRGRTVSTQVARPRH 518 >gi|343926497|ref|ZP_08766002.1| putative adenylate cyclase [Gordonia alkanivorans NBRC 16433] gi|343763735|dbj|GAA12928.1| putative adenylate cyclase [Gordonia alkanivorans NBRC 16433] Length=505 Score = 509 bits (1310), Expect = 6e-142, Method: Compositional matrix adjust. Identities = 263/499 (53%), Positives = 347/499 (70%), Gaps = 7/499 (1%) Query 36 RWVVRTPWPLFSLSMLQSDIIGALFVLGFLRYGLPPQDNIQLQDLPPVNLLIFVSTVIIL 95 RW++ TPWP+ +L ML+++++GALF FLR+G+P QD+I L ++ +N +IF S ++I Sbjct 6 RWLIHTPWPILALDMLRANLVGALFTFAFLRFGMPLQDSISLDEITALNQVIFASYLLIA 65 Query 96 FLAGAVVNLKLLMPVFRWQRRDNLLTEPDPAATELARSRALRMPLYRTLISLAVWATGGG 155 + G +++L +PV W RR L E AR RAL +P T+++ A+W GG Sbjct 66 MVIGGYASIQLSLPVLVWHRRRTRLD------NEAARRRALALPTLLTVVNAALWVVGGT 119 Query 156 VFILASWSVAKHAAPVVAVATALGATATAIIGYLQSERVLRPVAVAALRSGVPENVNAPG 215 +F L + +V+ A +VA+A+A+GA T + Y+Q+E+V+RP+ VAA+ + P + AP Sbjct 120 LFTLVNLTVSSKNAFIVAIASAIGAMVTCALSYMQAEKVMRPITVAAMANN-PNHAIAPS 178 Query 216 VILRLMLAWIPSTGVPLLAIVLAVAADKIALLHATPEALFNPILMMALAALGIGSVSTLL 275 V R+ W+ S P++ I+ + ++ + L PIL MA++AL ++ + Sbjct 179 VTTRITAFWVISVVAPMVVIIGLIVLHRLGIFEGDSTGLERPILWMAVSALAFSVIAIVR 238 Query 276 VAMSIADPLRQLRWALSEVQRGNYNAHMQIYDASELGLLQAGFNDMVRELSERQRLRDLF 335 V +I DP++QLR A S+V G+ N ++IYD S+LGLLQAGFNDMV +L ERQ LR+LF Sbjct 239 VVAAINDPIKQLRRAQSKVSDGDLNVAVKIYDGSDLGLLQAGFNDMVADLRERQELRNLF 298 Query 336 GRYVGEDVARRALERGTELGGQERDVAVLFVDLVGSTQLAATRPPAEVVQLLNEFFRVVV 395 GRYVGEDVARRA+E GTELGG+ER V VLFVD+VGST+LA RPP E+V+LLNEFFRVVV Sbjct 299 GRYVGEDVARRAIETGTELGGEERYVGVLFVDIVGSTRLAVNRPPREIVELLNEFFRVVV 358 Query 396 ETVARHGGFVNKFQGDAALAIFGAPIEHPDGAGAALSAARELHDELIPVLGSAEFGIGVS 455 V RHGGFVNKFQGDAALAIFGAP++ D AG AL++AREL EL LG + GIGVS Sbjct 359 AVVGRHGGFVNKFQGDAALAIFGAPLDLDDFAGRALASARELRAELYQTLGDTDIGIGVS 418 Query 456 AGRAIAGHIGAQARFEYTVIGDPVNEAARLTELAKLEDGHVLASAIAVSGALDAEALCWD 515 AG+AIAGHIGA+ R EYTVIGDPVNEAARLTELAK E VL SA AV A EA W+ Sbjct 419 AGKAIAGHIGAEQRLEYTVIGDPVNEAARLTELAKDEPTRVLGSARAVFLASHEEAEHWE 478 Query 516 VGEVVELRGRAAPTQLARP 534 +GE VELRGR T LARP Sbjct 479 IGEGVELRGRGIETLLARP 497 >gi|326383463|ref|ZP_08205150.1| adenylyl cyclase class-3/4/guanylyl cyclase [Gordonia neofelifaecis NRRL B-59395] gi|326197869|gb|EGD55056.1| adenylyl cyclase class-3/4/guanylyl cyclase [Gordonia neofelifaecis NRRL B-59395] Length=512 Score = 490 bits (1262), Expect = 2e-136, Method: Compositional matrix adjust. Identities = 263/507 (52%), Positives = 352/507 (70%), Gaps = 8/507 (1%) Query 35 VRWVVRTPWPLFSLSMLQSDIIGALFVLGFLRYGLPPQDNIQLQDLPPVNLLIFVSTVII 94 +RW+ TPWP+ +L ML++++IGALF FLR+G+P D+I + + N F ++I Sbjct 8 LRWLAHTPWPVLALDMLRANLIGALFTFAFLRFGMPRVDSISISEFNAQNQAAFGLYLVI 67 Query 95 LFLAGAVVNLKLLMPVFRWQRRDNLLTEPDPAATELARSRALRMPLYRTLISLAVWATGG 154 + GA ++++L MPV W RR L + E AR RAL +P TL++L +W GG Sbjct 68 AIVVGAYLSIQLSMPVLIWHRRRTRLDD------EAARKRALNLPTLLTLVNLGLWGVGG 121 Query 155 GVFILASWSVAKHAAPVVAVATALGATATAIIGYLQSERVLRPVAVAALRSGVPENVNAP 214 + + + + VV +A+ +GA TA++ ++Q+E+VLRP+ VAA+ + P+N NAP Sbjct 122 VILAVINLRTSIKDFVVVIIASLIGAMVTAVLSFMQAEKVLRPITVAAMAND-PDNSNAP 180 Query 215 GVILRLMLAWIPSTGVPLLAIVLAVAADKIALLHATPEALFNPILMMALAALGIGSVSTL 274 G+ R+ + WI S VP+ I V + ++ E L PIL MA AA+ G ++ Sbjct 181 GIATRITVFWIVSVAVPMSVIAALVLLQRFGVIDTDAEGLERPILWMAAAAVVFGLLAIT 240 Query 275 LVAMSIADPLRQLRWALSEVQRGNYNAHMQIYDASELGLLQAGFNDMVRELSERQRLRDL 334 + SI DP++Q+R AL++V+ GN N ++IYD ++LGLLQAGFN+MV +L ERQ LR+L Sbjct 241 RLVRSITDPVKQMRVALNQVRAGNLNVAVKIYDGNDLGLLQAGFNEMVADLRERQELRNL 300 Query 335 FGRYVGEDVARRALERGTELGGQERDVAVLFVDLVGSTQLAATRPPAEVVQLLNEFFRVV 394 FGRYVGEDVARRA+E GTELGG+ER V VLFVD+VGST+LA RPP EVV+LLN+FF+VV Sbjct 301 FGRYVGEDVARRAIETGTELGGEERYVGVLFVDIVGSTRLAVNRPPREVVELLNDFFQVV 360 Query 395 VETVARHGGFVNKFQGDAALAIFGAPIEHPDGAGAALSAARELHDELIPVLGSAEFGIGV 454 V+ V RHGGFVNKFQGDAALAIFGAP++ D +G+AL+AAR+L EL LG + GIGV Sbjct 361 VDVVGRHGGFVNKFQGDAALAIFGAPLDQADFSGSALAAARDLRVELARRLGDVDMGIGV 420 Query 455 SAGRAIAGHIGAQARFEYTVIGDPVNEAARLTELAKLEDGHVLASAIAVSGALDAEALCW 514 SAG+A+AGHIG++ R EYTVIGDPVNEAARLTELAK E VL SA AV A D EA W Sbjct 421 SAGKAVAGHIGSEQRLEYTVIGDPVNEAARLTELAKDEPTRVLGSARAVFLAGDDEAEHW 480 Query 515 DVGEVVELRGRAAPTQLARP-MNLAAP 540 +GE VELRGR T LARP +++A P Sbjct 481 RIGEGVELRGRGIETLLARPDIDVAEP 507 >gi|262200590|ref|YP_003271798.1| adenylyl cyclase class-3/4/guanylyl cyclase [Gordonia bronchialis DSM 43247] gi|262083937|gb|ACY19905.1| adenylyl cyclase class-3/4/guanylyl cyclase [Gordonia bronchialis DSM 43247] Length=504 Score = 484 bits (1245), Expect = 2e-134, Method: Compositional matrix adjust. Identities = 268/500 (54%), Positives = 351/500 (71%), Gaps = 7/500 (1%) Query 36 RWVVRTPWPLFSLSMLQSDIIGALFVLGFLRYGLPPQDNIQLQDLPPVNLLIFVSTVIIL 95 RW+V TPWP+ +L ML+++++GALF FLR+G+P QD+I L ++ +N +IF +II Sbjct 5 RWLVHTPWPILALDMLRANLVGALFTFAFLRFGMPLQDSISLDEITALNQVIFAFYLIIA 64 Query 96 FLAGAVVNLKLLMPVFRWQRRDNLLTEPDPAATELARSRALRMPLYRTLISLAVWATGGG 155 L G ++++L +PV W RR L E AR RAL +P+ + ++ A+W GG Sbjct 65 MLVGGFLSIQLSLPVLIWHRRRTRLD------NESARRRALALPMLLSAVNAALWMIGGV 118 Query 156 VFILASWSVAKHAAPVVAVATALGATATAIIGYLQSERVLRPVAVAALRSGVPENVNAPG 215 +F L + +V+ A +VA+A+ +GA T + Y+Q+E+VLRP+ VAA+ + P+N AP Sbjct 119 LFTLVNLTVSNKNAFIVAIASVIGALVTCALSYMQAEKVLRPITVAAMAND-PDNAIAPS 177 Query 216 VILRLMLAWIPSTGVPLLAIVLAVAADKIALLHATPEALFNPILMMALAALGIGSVSTLL 275 V R+ W+ S P++ IV + ++ + A L PIL MAL+AL ++ + Sbjct 178 VTTRITTFWVISAVAPMMVIVGLIVLHRLGFIEADATGLERPILWMALSALAFSLLAIVR 237 Query 276 VAMSIADPLRQLRWALSEVQRGNYNAHMQIYDASELGLLQAGFNDMVRELSERQRLRDLF 335 V +I DP++QLR A S+V GN + ++IYD S+LGLLQAGFNDMV +L ERQ+LR+LF Sbjct 238 VVSAINDPIKQLRRAQSQVSAGNLDVAVKIYDGSDLGLLQAGFNDMVSDLRERQQLRNLF 297 Query 336 GRYVGEDVARRALERGTELGGQERDVAVLFVDLVGSTQLAATRPPAEVVQLLNEFFRVVV 395 GRYVGEDVAR+A+E GTELGG+ER V VLFVD+VGST+LA RPP E+V+LLNEFFRVVV Sbjct 298 GRYVGEDVARKAIETGTELGGEERYVGVLFVDIVGSTRLAVNRPPREIVELLNEFFRVVV 357 Query 396 ETVARHGGFVNKFQGDAALAIFGAPIEHPDGAGAALSAARELHDELIPVLGSAEFGIGVS 455 E V RHGGFVNKFQGDAALAIFGAP++ D AG AL++AREL EL LG + GIGVS Sbjct 358 EVVGRHGGFVNKFQGDAALAIFGAPLDLEDFAGRALASARELRAELYETLGDTDIGIGVS 417 Query 456 AGRAIAGHIGAQARFEYTVIGDPVNEAARLTELAKLEDGHVLASAIAVSGALDAEALCWD 515 AG+AIAGHIGA+ R EYTVIGDPVNEAARLTELAK E VL SA AV A EA W+ Sbjct 418 AGKAIAGHIGAEQRLEYTVIGDPVNEAARLTELAKDEPTRVLGSARAVFLASREEAEHWE 477 Query 516 VGEVVELRGRAAPTQLARPM 535 +GE VELRGR T LARP+ Sbjct 478 IGEGVELRGRGIETLLARPL 497 >gi|296141546|ref|YP_003648789.1| adenylate/guanylate cyclase with integral membrane sensor [Tsukamurella paurometabola DSM 20162] gi|296029680|gb|ADG80450.1| adenylate/guanylate cyclase with integral membrane sensor [Tsukamurella paurometabola DSM 20162] Length=499 Score = 475 bits (1223), Expect = 8e-132, Method: Compositional matrix adjust. Identities = 256/500 (52%), Positives = 351/500 (71%), Gaps = 8/500 (1%) Query 36 RWVVRTPWPLFSLSMLQSDIIGALFVLGFLRYGLPPQDNIQLQDLPPVNLLIFVSTVIIL 95 RW+ +TPWP+F+L +L+S+I+GA+FV GFLR+ LP ++Q+Q + +NLL+FV+ ++ Sbjct 5 RWLAKTPWPIFALDILRSNILGAVFVFGFLRFALPVNQSVQIQQISGINLLVFVAYLLGA 64 Query 96 FLAGAVVNLKLLMPVFRWQRRDNLLTEPDPAATELARSRALRMPLYRTLISLAVWATGGG 155 + G +V L+L++PV RW RR P ++++ R L +P L+ +W GG Sbjct 65 TVIGTIVGLRLVLPVLRWHRRSA------PNDLDISQ-RVLALPSRMALLQAILWLVGGA 117 Query 156 VFILASWSVAKHAAPVVAVATALGATATAIIGYLQSERVLRPVAVAALRSGVPENVNAPG 215 +F++ ++ A V+A+ LGA T + Y+Q+ERVLRP+ VAAL + P+ Sbjct 118 LFVVINFDAPTGAPAVIAMTVFLGAATTCALSYMQTERVLRPITVAAL-AQEPQGTAGLS 176 Query 216 VILRLMLAWIPSTGVPLLAIVLAVAADKIALLHATPEALFNPILMMALAALGIGSVSTLL 275 V R+ML+W+ T VP++ I++ + L+ ++ +P+L+++L AL G + + Sbjct 177 VNTRIMLSWLLGTAVPIIGILMVILLQDFGLVDPDAPSIIDPVLLLSLVALAAGLLGMVR 236 Query 276 VAMSIADPLRQLRWALSEVQRGNYNAHMQIYDASELGLLQAGFNDMVRELSERQRLRDLF 335 A SI DP+R L A V+ G++N ++IYD+SELGLLQAGFNDMV +L+ERQR+RD+F Sbjct 237 AAKSIGDPIRDLFRAQRRVRDGDFNTSVKIYDSSELGLLQAGFNDMVHDLAERQRMRDMF 296 Query 336 GRYVGEDVARRALERGTELGGQERDVAVLFVDLVGSTQLAATRPPAEVVQLLNEFFRVVV 395 GRYVGEDVAR+ALE GT L G+ R+V VLFVDLVGST+LA T PA VV LLN+FF+VVV Sbjct 297 GRYVGEDVARQALEHGTHLEGEIREVGVLFVDLVGSTKLAVTEEPAAVVDLLNDFFKVVV 356 Query 396 ETVARHGGFVNKFQGDAALAIFGAPIEHPDGAGAALSAARELHDELIPVLGSAEFGIGVS 455 + V HGGFVNKFQGDAALAIFGAP+ HPD +GAAL+AARE+ +L VLG FGIGVS Sbjct 357 DLVDLHGGFVNKFQGDAALAIFGAPLPHPDASGAALAAAREMRFQLRDVLGGTGFGIGVS 416 Query 456 AGRAIAGHIGAQARFEYTVIGDPVNEAARLTELAKLEDGHVLASAIAVSGALDAEALCWD 515 AG+ +AGHIGA+ARFEYTVIGDPVNEAAR+TE+AK E +LA+ AV A AE W Sbjct 417 AGQVVAGHIGAKARFEYTVIGDPVNEAARITEIAKSEPSSLLAAGRAVESATAAEQALWA 476 Query 516 VGEVVELRGRAAPTQLARPM 535 +GE +ELRGR TQLARP+ Sbjct 477 LGEAIELRGRGQLTQLARPL 496 >gi|319951223|ref|ZP_08025061.1| putative adenylate cyclase [Dietzia cinnamea P4] gi|319435122|gb|EFV90404.1| putative adenylate cyclase [Dietzia cinnamea P4] Length=523 Score = 437 bits (1124), Expect = 3e-120, Method: Compositional matrix adjust. Identities = 238/500 (48%), Positives = 322/500 (65%), Gaps = 8/500 (1%) Query 36 RWVVRTPWPLFSLSMLQSDIIGALFVLGFLRYGLPPQDNIQLQDLPPVNLLIFVSTVIIL 95 RW+ TPWP+++L+M+Q++IIGA+FV FLR+ LP + L + +N +F+ +++ Sbjct 9 RWLWATPWPVYALTMVQANIIGAVFVFSFLRFVLPVDRFLDLDEFRFLNQYLFIGYLVLA 68 Query 96 FLAGAVVNLKLLMPVFRWQRRDNLLTEPDPAATELARSRALRMPLYRTLISLAVWATGGG 155 F+ G + + LL+PV R R E D A R R LR+P ++ +IS +W G Sbjct 69 FIGGVIASTLLLLPVLRVDRAG---AEFDGAI----RRRTLRLPFHQAIISGTMWLIGTL 121 Query 156 VFILASWSVAKHAAPVVAVATALGATATAIIGYLQSERVLRPVAVAALRSGVPENVNAPG 215 +F + + A +V+V + LG + T +I YLQ+ER++RP+ V AL SGVP N + PG Sbjct 122 LFAAVNVGHSPRLALIVSVTSLLGGSTTVLISYLQAERIMRPITVRALASGVPANRHVPG 181 Query 216 VILRLMLAWIPSTGVPLLAIVLAVAADKIALLHATPEALFNPILMMALAALGIGSVSTLL 275 V R+ L W +T +P+ I+L + L P + + ++A A+ G++ L Sbjct 182 VRRRIFLGWALTTVIPIAGILLILTGHWFGLFGDDPGTILVALAVLASVAVIAGAIGMGL 241 Query 276 VAMSIADPLRQLRWALSEVQRGNYNAHMQIYDASELGLLQAGFNDMVRELSERQRLRDLF 335 V+ SIADP+R+++ +S V++G+ + IYD+SE+G L GFN+MV L ER+ ++DLF Sbjct 242 VSDSIADPVREMQAGVSRVKQGDLETRVTIYDSSEIGRLAQGFNEMVTGLQEREAIQDLF 301 Query 336 GRYVGEDVARRALERGTELGGQERDVAVLFVDLVGSTQLAATRPPAEVVQLLNEFFRVVV 395 GRYVGEDVAR ALERGTELGGQER+VAVLFVDL GST+ AA PAEVV +LNEFFR+ V Sbjct 302 GRYVGEDVARNALERGTELGGQEREVAVLFVDLTGSTEFAAAHEPAEVVSVLNEFFRIAV 361 Query 396 ETVARHGGFVNKFQGDAALAIFGAPIEHPDGAGAALSAARELHDELIPVLGSAEFGIGVS 455 E V +GG++NKFQGDA LA+FGAP+E D A + L GIGVS Sbjct 362 EAVDSNGGYINKFQGDALLAVFGAPLE-VDNEAGRALRAARALQSRLAELSPLSAGIGVS 420 Query 456 AGRAIAGHIGAQARFEYTVIGDPVNEAARLTELAKLEDGHVLASAIAVSGALDAEALCWD 515 G IAGHIG RFEYTVIGDPVNEAARLT LAK+E GHVLASA + A D EA W Sbjct 421 YGTVIAGHIGHAKRFEYTVIGDPVNEAARLTTLAKMEQGHVLASAATIHHADDPEAARWV 480 Query 516 VGEVVELRGRAAPTQLARPM 535 +G+ VELRGR TQLARP+ Sbjct 481 LGQSVELRGRGIMTQLARPL 500 >gi|226304564|ref|YP_002764522.1| adenylate cyclase [Rhodococcus erythropolis PR4] gi|226183679|dbj|BAH31783.1| putative adenylate cyclase [Rhodococcus erythropolis PR4] Length=511 Score = 402 bits (1033), Expect = 9e-110, Method: Compositional matrix adjust. Identities = 239/499 (48%), Positives = 317/499 (64%), Gaps = 14/499 (2%) Query 39 VRTPWPLFSLSMLQSDIIGALFVLGFLRYGLPPQDNIQLQDLPPVNLLIFVSTVIILFLA 98 +R+ WPL+ LSML +++IGA+ V F+RYG+P Q++ + N IF + L A Sbjct 12 IRSRWPLYMLSMLAANLIGAVLVFAFVRYGVPIQESDAIVADRVRNFAIFG---VYLAFA 68 Query 99 GAV---VNLKLLMPVFRWQRRDNLLTEPDPAATELARSRALRMPLYRTLISLAVWATGGG 155 GAV +L V RW+ R T + A AL PL + ++ L +W GG Sbjct 69 GAVSLTAAAMMLKSVIRWRLRGGPPTRSEQMA-------ALHAPLRQAIVHLVLWILGGI 121 Query 156 VFILASWSVAKHAAPVVAVATALGATATAIIGYLQSERVLRPVAVAALRSGVPENVNAPG 215 +F+ + + A V V + AT T Y+ ER+LRPVA AL G + APG Sbjct 122 IFVFLTITEMPGLAIAVIVTVCMAATTTFGFTYMLGERILRPVAAQALSEGEFDRTMAPG 181 Query 216 VILRLMLAWIPSTGVPLLAIVLAVAADKIALLHATPEALFNPILMMALAALGIGSVSTLL 275 V RL + W T +P+ I+L + L +P++L IL++++ A+ ++L Sbjct 182 VGTRLAMTWGLGTLMPVAGIILLCSTQLTTNLEFSPDSLAWAILLISIMAIVQAFALSML 241 Query 276 VAMSIADPLRQLRWALSEVQRGNYNAHMQIYDASELGLLQAGFNDMVRELSERQRLRDLF 335 A I+DP+RQLR A+ VQRG + ++++D SE+G LQ GFN M++E ER+ LR+LF Sbjct 242 TATQISDPIRQLRRAIERVQRGATDVRVEVFDGSEIGRLQVGFNRMMKESDERRLLRELF 301 Query 336 GRYVGEDVARRALERGTELGGQERDVAVLFVDLVGSTQLAATRPPAEVVQLLNEFFRVVV 395 G++VGEDVARRAL+ GTELGG+ R VAVLFVD+VGST AA RPP EVV+LLNEFFRVVV Sbjct 302 GQHVGEDVARRALKFGTELGGETRFVAVLFVDMVGSTGAAAERPPGEVVELLNEFFRVVV 361 Query 396 ETVARHGGFVNKFQGDAALAIFGAPIEHPDGAGAALSAARELHDELIPVLGSAEFGIGVS 455 + + RH GFVNKF GDAALAIFGAP++ PD AAL+AAREL +L + G + GIGVS Sbjct 362 DVIDRHHGFVNKFMGDAALAIFGAPLDRPDAPTAALAAARELRFKLNDITG-LDVGIGVS 420 Query 456 AGRAIAGHIGAQARFEYTVIGDPVNEAARLTELAKLEDGHVLASAIAVSGALDAEALCWD 515 AG A+AG+IGA RFEYTVIGDPVNEA+RLTELAKL VLAS A+ A + E W+ Sbjct 421 AGLAVAGNIGAAERFEYTVIGDPVNEASRLTELAKLRPSRVLASTSALYFADEEEQAEWE 480 Query 516 VGEVVELRGRAAPTQLARP 534 +GE V+LRGR T LA P Sbjct 481 LGEQVQLRGRRRLTHLAWP 499 >gi|226364628|ref|YP_002782410.1| adenylate cyclase [Rhodococcus opacus B4] gi|226243117|dbj|BAH53465.1| adenylate cyclase [Rhodococcus opacus B4] Length=504 Score = 400 bits (1029), Expect = 2e-109, Method: Compositional matrix adjust. Identities = 236/506 (47%), Positives = 316/506 (63%), Gaps = 8/506 (1%) Query 29 RRIHAFVRWVVRTPWPLFSLSMLQSDIIGALFVLGFLRYGLPPQDNIQLQDLPPVNLLIF 88 R+ + + VR+ WPL+ +SML ++ IGA+ V F+RYG+P ++ + N+ IF Sbjct 2 RKSYRAIAATVRSRWPLYMVSMLLANFIGAILVFAFVRYGVPIPESQAIMADRVRNVAIF 61 Query 89 VSTVIILFLAGAVVNLKLLMPVFRWQRRDNLLTEPDPAATELARSRALRMPLYRTLISLA 148 + + +L V RWQ R P +E + AL PL + ++ L Sbjct 62 GGYLAFAAVVSLTAAAMMLRSVVRWQLRGG-----PPTRSE--QMSALHAPLRQAIVHLV 114 Query 149 VWATGGGVFILASWSVAKHAAPVVAVATALGATATAIIGYLQSERVLRPVAVAALRSGVP 208 +W GG +F+L + + A V V + AT T Y+ ER+LRPVA AL G Sbjct 115 LWILGGIIFVLLTITEMPELAVAVIVTVCMAATTTFGFTYMLGERILRPVAARALSEGEF 174 Query 209 ENVNAPGVILRLMLAWIPSTGVPLLAIVLAVAADKIALLHATPEALFNPILMMALAALGI 268 + APGV R+ + W T +P++ I+L L +P+AL I+++++ A+ Sbjct 175 DRTMAPGVGTRMAMTWGLGTLMPVIGIILLCVTQITTDLVFSPDALAWAIMLLSIIAIAQ 234 Query 269 GSVSTLLVAMSIADPLRQLRWALSEVQRGNYNAHMQIYDASELGLLQAGFNDMVRELSER 328 ++L A I+DP++QLR A+ VQRG + ++++D SE+G LQ GFN M+RE ER Sbjct 235 AFALSMLTASQISDPIKQLRRAIERVQRGATDVRVEVFDGSEVGRLQVGFNRMMRESDER 294 Query 329 QRLRDLFGRYVGEDVARRALERGTELGGQERDVAVLFVDLVGSTQLAATRPPAEVVQLLN 388 + LR+LFG++VGEDVARRAL+ GTELGG+ R VAVLFVD+VGST AA RPP EVV LLN Sbjct 295 RLLRELFGQHVGEDVARRALQFGTELGGETRFVAVLFVDMVGSTGAAAERPPGEVVNLLN 354 Query 389 EFFRVVVETVARHGGFVNKFQGDAALAIFGAPIEHPDGAGAALSAARELHDELIPVLGSA 448 EFFRVVV+ + RH GFVNKF GDAALAIFGAP++ PD AAL+AAREL L + G Sbjct 355 EFFRVVVDVIDRHHGFVNKFMGDAALAIFGAPLDRPDAPTAALAAARELRFALNEITG-L 413 Query 449 EFGIGVSAGRAIAGHIGAQARFEYTVIGDPVNEAARLTELAKLEDGHVLASAIAVSGALD 508 + GIGVSAG A+AG+IGA RFEYTVIGDPVNEA+RLTELAKL VLAS A+ A D Sbjct 414 DVGIGVSAGLAVAGNIGAAERFEYTVIGDPVNEASRLTELAKLHPSRVLASTSALYFADD 473 Query 509 AEALCWDVGEVVELRGRAAPTQLARP 534 E W++GE V+LRGR T LA P Sbjct 474 DEQAHWELGEQVQLRGRRRNTHLAWP 499 >gi|334564335|ref|ZP_08517326.1| adenylate cyclase [Corynebacterium bovis DSM 20582] Length=561 Score = 396 bits (1018), Expect = 4e-108, Method: Compositional matrix adjust. Identities = 226/512 (45%), Positives = 323/512 (64%), Gaps = 19/512 (3%) Query 31 IHAFVR---WVVRTPWPLFSLSMLQSDIIGALFVLGFLRYGLPPQDNIQLQDLPPVNLLI 87 + FVR WV T WPL++ ++L +++G++ V FLR+ +P ++ L + Sbjct 1 MKQFVRYLAWVWGTSWPLYAATVLFINVLGSVAVASFLRFLVPLAGAREITRLDTTTAAL 60 Query 88 FVSTVIILFLAGAVVNLKLLMPVFRWQRRDNLLTEPDPAATELARSRALRMPLYRTLISL 147 + + I +AG V L PV RWQR P + R+ LR+P +T++ Sbjct 61 YGAYFFIAVVAGVTVTLHFFAPVLRWQR------SPGTYDPNMVRALVLRIPALQTILGA 114 Query 148 AVWATGGGVFILASWSVAKHAAPVVAVATALGATAT----AIIGYLQSERVLRPVAVAAL 203 +W G +F +VA H + +A + AT T ++ YL +ER++RPVA AL Sbjct 115 VLWGVGVILFT----AVAAHHSTRWGIAVGVAATLTGAMVCLLTYLVAERLVRPVAAKAL 170 Query 204 RSGVPENVNAPGVILRLMLAWIPSTGVPLLAIVLAVAADKIALLHATPEALFNPILMMAL 263 GVP++ + L+LM +WI ++ VP+L I+L VAA + + ++ ++L Sbjct 171 TRGVPDHSKISPLSLQLMGSWILTSAVPVLGILLLVAAQVSGMFTTDAREILPGVVALSL 230 Query 264 AALGIGSVSTLLVAMSIADPLRQLRWALSEVQRGNYNAHMQIYDASELGLLQAGFNDMVR 323 A+ G T LV M++ DP+R+L+ A++ V+RG + ++IYD+SE+G+LQAGFN+M+R Sbjct 231 TAILTGFSGTRLVTMNVVDPIRELQTAMNRVRRGGTDTTVRIYDSSEIGVLQAGFNEMMR 290 Query 324 ELSERQRLRDLFGRYVGEDVARRALERGTELGGQERDVAVLFVDLVGSTQLAATRPPAEV 383 L +R+++R+LFGRYVG++VARRALE ELGG+ R VAVLFVD++GST A +R PA V Sbjct 291 GLRDREQVRELFGRYVGDEVARRALEEKPELGGENRAVAVLFVDVIGSTGFAVSREPAHV 350 Query 384 VQLLNEFFRVVVETVARHGGFVNKFQGDAALAIFGAPIEHPDGAGAALSAARELHDELIP 443 V LNEFF VV+ V R+ G +NKF+GDAALA+FGAP+ D AG AL+AARELH +L Sbjct 351 VHALNEFFDRVVDVVHRNRGMINKFEGDAALAVFGAPVPLDDIAGHALAAARELHRDLGG 410 Query 444 VLGSAEFGIGVSAGRAIAGHIGAQARFEYTVIGDPVNEAARLTELAKLEDGHVLASAIAV 503 + E GIGV+AG +AGHIGA+ RFE+TVIGD VN+AARLT+LAK GHVL SA V Sbjct 411 L--ELEAGIGVAAGNVVAGHIGAKDRFEFTVIGDAVNQAARLTDLAKKTPGHVLTSAATV 468 Query 504 SGALDAEALCWDVGEVVELRGRAAPTQLARPM 535 A +AE W + + VELRGR TQLARP+ Sbjct 469 RQANEAEQARWTMMKSVELRGRREMTQLARPV 500 >gi|38232953|ref|NP_938720.1| putative adenylate cyclase [Corynebacterium diphtheriae NCTC 13129] gi|38199211|emb|CAE48839.1| Putative adenylate cyclase [Corynebacterium diphtheriae] Length=508 Score = 396 bits (1017), Expect = 5e-108, Method: Compositional matrix adjust. Identities = 213/500 (43%), Positives = 311/500 (63%), Gaps = 8/500 (1%) Query 36 RWVVRTPWPLFSLSMLQSDIIGALFVLGFLRYGLPPQDNIQLQDLPPVNLLIFVSTVIIL 95 +W+ +T WPL++ ++L S+++GA+ V+ FL+Y +P + Q D + + +I+ Sbjct 9 KWLFKTSWPLYATTVLGSNVLGAVGVMLFLKYLVPLPEFDQFTDEASYLPELGIGYLILA 68 Query 96 FLAGAVVNLKLLMPVFRWQRRDNLLTEPDPAATELARSRALRMPLYRTLISLAVWATGGG 155 + G V L PV WQR PD + R+ +R+P+Y+ + VWA G Sbjct 69 VIFGGAVTFLLFRPVLDWQR------HPDTHDPNMVRNLVMRIPIYQAALCSVVWALGIV 122 Query 156 VFILASWSVAKHAAPVVAVATALGATATAIIGYLQSERVLRPVAVAALRSGVPENVNAPG 215 V +A+ + A +AVA+ L ++ YL+++R++RPVA AL ++ P Sbjct 123 VLAIAAGQTSPRLALAIAVASTLSGAVIVVLTYLEAQRLVRPVAATALARRFEDSTLEPP 182 Query 216 VILRLMLAWIPSTGVPLLAIVLAVAADKIALLHATPEALFNPILMMALAALGIGSVSTLL 275 + RL L W ++ VP++ I+L V + + + ++ +A+AAL G + T L Sbjct 183 ITSRLRLTWALTSAVPIIGILLMVMGHHLGMFTDNVSDIMPAVIALAMAALITGFLGTTL 242 Query 276 VAMSIADPLRQLRWALSEVQRGNYNAHMQIYDASELGLLQAGFNDMVRELSERQRLRDLF 335 MS+ DP+ +L+ A++ V+RG+ + IYD SE+G+LQAGFN+M+R L ERQR+RD+F Sbjct 243 SIMSVVDPILELQGAINRVRRGDSGVQVDIYDGSEIGVLQAGFNEMMRGLKERQRVRDIF 302 Query 336 GRYVGEDVARRALERGTELGGQERDVAVLFVDLVGSTQLAATRPPAEVVQLLNEFFRVVV 395 GRYVG +VARRALE +LGG++R+VAV+FVD++GST A P EVV+ LN FF VV Sbjct 303 GRYVGVEVARRALEERPQLGGEDREVAVVFVDVIGSTTFAVNHDPEEVVEELNRFFEHVV 362 Query 396 ETVARHGGFVNKFQGDAALAIFGAPIEHPDGAGAALSAARELHDELIPVLGSAEFGIGVS 455 E V R+ G +NKFQGDAALA+FGAP+ D G AL+AAREL EL+ + E GIGV+ Sbjct 363 EVVHRNKGIINKFQGDAALAVFGAPVTLSDATGHALTAARELRQELMGL--RLEAGIGVA 420 Query 456 AGRAIAGHIGAQARFEYTVIGDPVNEAARLTELAKLEDGHVLASAIAVSGALDAEALCWD 515 +G +AGHIG RFEYTVIGD VN AARLTE+AK G VL ++ + A +AE W Sbjct 421 SGHVVAGHIGGHDRFEYTVIGDAVNTAARLTEIAKNTPGRVLTNSATLQRANEAEQARWT 480 Query 516 VGEVVELRGRAAPTQLARPM 535 + + VELRGR+ TQLARP+ Sbjct 481 MMKSVELRGRSLMTQLARPI 500 >gi|227505639|ref|ZP_03935688.1| adenylate cyclase [Corynebacterium striatum ATCC 6940] gi|227197792|gb|EEI77840.1| adenylate cyclase [Corynebacterium striatum ATCC 6940] Length=510 Score = 395 bits (1015), Expect = 9e-108, Method: Compositional matrix adjust. Identities = 216/503 (43%), Positives = 314/503 (63%), Gaps = 14/503 (2%) Query 36 RWVVRTPWPLFSLSMLQSDIIGALFVLGFLRYGLP-PQDNIQLQDLPPVNLL--IFVSTV 92 RW++ T WP+++ +L S+I+GA+ ++ F+ + LP P+ D+P + L+ ++V+ Sbjct 9 RWLMGTQWPMYATLVLGSNIVGAIAIMTFVVFFLPMPEIKDFTSDVPNLELVGALYVTFA 68 Query 93 IILFLAGAVVNLKLLMPVFRWQRRDNLLTEPDPAATELARSRALRMPLYRTLISLAVWAT 152 +++ G V L L PV WQR PD + R+ LR+P+Y+ ++ VW Sbjct 69 VVI---GIAVTLLLFRPVLDWQR------NPDAHDPNMVRNLVLRIPVYQAAVAALVWVI 119 Query 153 GGGVFILASWSVAKHAAPVVAVATALGATATAIIGYLQSERVLRPVAVAALRSGVPENVN 212 G + ++ + + VV V+T L ++ YLQ+ER++RPVA A+ ++ Sbjct 120 GIILAVVIASQSSGRLGLVVGVSTTLAGLLVVLLTYLQAERLVRPVAAQAVARRFEDSTL 179 Query 213 APGVILRLMLAWIPSTGVPLLAIVLAVAADKIALLHATPEALFNPILMMALAALGIGSVS 272 P + RL+ W+ ++G+PL+ IVL + + L + ++ +AL ALG G Sbjct 180 EPPIKYRLIFTWVMTSGIPLIGIVLVLLGRRAGLFTDNSTDIMPAVIALALTALGTGFTG 239 Query 273 TLLVAMSIADPLRQLRWALSEVQRGNYNAHMQIYDASELGLLQAGFNDMVRELSERQRLR 332 T+ MS+ DP+ +L+ A++ V+RG + + IYD SELG+LQAGFN+M+R L ERQR+R Sbjct 240 TVFAMMSVVDPILELQDAINRVRRGENDVQVDIYDGSELGVLQAGFNEMMRGLRERQRVR 299 Query 333 DLFGRYVGEDVARRALERGTELGGQERDVAVLFVDLVGSTQLAATRPPAEVVQLLNEFFR 392 D+FGRYVG +VA+RALE ELGG++R VAVLF+D++GST A P EVV+ LN+FF Sbjct 300 DIFGRYVGTEVAQRALEERPELGGEDRKVAVLFIDVIGSTTFAVNHTPEEVVEALNKFFE 359 Query 393 VVVETVARHGGFVNKFQGDAALAIFGAPIEHPDGAGAALSAARELHDELIPVLGSAEFGI 452 VVE V R+ G +NKFQGDAALA+FGAP+ D AL AAREL EL + + GI Sbjct 360 HVVEVVHRNKGIINKFQGDAALAVFGAPLNVYDANSMALQAARELRQELRGL--ELQAGI 417 Query 453 GVSAGRAIAGHIGAQARFEYTVIGDPVNEAARLTELAKLEDGHVLASAIAVSGALDAEAL 512 GV+AG +AGHIG RFEYTVIGD VNEAARLTELAK G VL ++ + GA +AE Sbjct 418 GVAAGHVVAGHIGGADRFEYTVIGDAVNEAARLTELAKDTPGQVLTNSATLRGANEAEQA 477 Query 513 CWDVGEVVELRGRAAPTQLARPM 535 W + + +ELRGR T+LARP+ Sbjct 478 RWTMMKSIELRGRRRMTRLARPI 500 >gi|296118103|ref|ZP_06836685.1| putative adenylate cyclase [Corynebacterium ammoniagenes DSM 20306] gi|295968989|gb|EFG82232.1| putative adenylate cyclase [Corynebacterium ammoniagenes DSM 20306] Length=510 Score = 393 bits (1010), Expect = 3e-107, Method: Compositional matrix adjust. Identities = 221/507 (44%), Positives = 308/507 (61%), Gaps = 10/507 (1%) Query 30 RIHAFVRWVVRTPWPLFSLSMLQSDIIGALFVLGFLRYGLPPQDNIQLQDLPPVNLL-IF 88 R+ + W++ T WP+++ +L ++I+GA+ ++ F+ + LP + IQ NL + Sbjct 3 RVMRGISWLMSTSWPIYAAIVLGTNIVGAVAIMTFVVFFLPMPE-IQEFTRNFDNLFGLG 61 Query 89 VSTVIILFLAGAVVNLKLLMPVFRWQRRDNLLTEPDPAATELARSRALRMPLYRTLISLA 148 + VI + G + L PV+ WQR PD + R+ +R+P+Y+ ++ Sbjct 62 AAYVIFAVIVGMAATILLFRPVWDWQR------NPDAHDPNMVRNLVMRIPIYQAAVAAL 115 Query 149 VWATGGGVFILASWSVAKHAAPVVAVATALGATATAIIGYLQSERVLRPVAVAALRSGVP 208 VW G G+ + + + A VV V++ L +I YLQ+ER++RPVA AL Sbjct 116 VWLIGIGITVAITSASDARLALVVGVSSTLAGMIVVLITYLQAERMVRPVAATALARRFE 175 Query 209 ENVNAPGVILRLMLAWIPSTGVPLLAIVLAVAADKIALLHATPEALFNPILMMALAALGI 268 ++ P + RL L+WI STGVPLL IVL A L + ++ + L A G Sbjct 176 DSTLEPPIKQRLYLSWIMSTGVPLLGIVLVFVAQTSGLFTDNANDILPAVVALTLTAFGT 235 Query 269 GSVSTLLVAMSIADPLRQLRWALSEVQRGNYNAHMQIYDASELGLLQAGFNDMVRELSER 328 G+++T MS+ DP+ +L+ A++ V+RG + + IYD SELG+LQAGFN+M+R L ER Sbjct 236 GAMATAYSTMSVVDPIYELQDAINRVRRGERHVEVDIYDGSELGVLQAGFNEMMRGLHER 295 Query 329 QRLRDLFGRYVGEDVARRALERGTELGGQERDVAVLFVDLVGSTQLAATRPPAEVVQLLN 388 QRLRDLFGRYVG++VA+RAL+ ELGG++R VAVLF+D++GST A P VV+ LN Sbjct 296 QRLRDLFGRYVGDEVAQRALDERPELGGEDRKVAVLFIDVIGSTTFAVNNTPERVVEELN 355 Query 389 EFFRVVVETVARHGGFVNKFQGDAALAIFGAPIEHPDGAGAALSAARELHDELIPVLGSA 448 FF VVE V R+ G +NKFQGDAALAIFGAP+ D AL AAREL EL + Sbjct 356 NFFEHVVEVVHRNKGIINKFQGDAALAIFGAPLNVYDSTSMALQAARELRHELRNL--EL 413 Query 449 EFGIGVSAGRAIAGHIGAQARFEYTVIGDPVNEAARLTELAKLEDGHVLASAIAVSGALD 508 + GIGV++G +AGHIG RFEYTVIGD VNEAARLTELAK G VL +A + A + Sbjct 414 QAGIGVASGHVVAGHIGGLDRFEYTVIGDAVNEAARLTELAKETPGRVLTNASTLKNANE 473 Query 509 AEALCWDVGEVVELRGRAAPTQLARPM 535 E W + +ELRGR TQLARP+ Sbjct 474 TEQARWTFMKSIELRGRRRMTQLARPI 500 >gi|172041526|ref|YP_001801241.1| adenylate cyclase, putative [Corynebacterium urealyticum DSM 7109] gi|171852830|emb|CAQ05806.1| adenylate cyclase, putative [Corynebacterium urealyticum DSM 7109] Length=687 Score = 392 bits (1008), Expect = 6e-107, Method: Compositional matrix adjust. Identities = 225/502 (45%), Positives = 313/502 (63%), Gaps = 8/502 (1%) Query 34 FVRWVVRTPWPLFSLSMLQSDIIGALFVLGFLRYGLPPQDNIQLQDLPPVNLLIFVSTVI 93 +++WV T WPL++ +L ++++GA+ V FLR+ +P + +L V + ++S I Sbjct 186 YLKWVWGTYWPLYAAMILMTNVVGAIAVATFLRFLIPLRGARELTSPNTVTSIAYLSYFI 245 Query 94 ILFLAGAVVNLKLLMPVFRWQRRDNLLTEPDPAATELARSRALRMPLYRTLISLAVWATG 153 +AG V L PV RWQR PD + R LR+P +++ +WA G Sbjct 246 FAIVAGVVFTLIFFAPVLRWQR------NPDAYDPNMIRHLVLRIPFLQSVTGAVLWAIG 299 Query 154 GGVFILASWSVAKHAAPVVAVATALGATATAIIGYLQSERVLRPVAVAALRSGVPENVNA 213 +F + + A VAV LG ++ Y+++ER++RPVA AL G E + Sbjct 300 VVIFTTVAAQFSSRWAITVAVTAVLGGLMVTLMTYMEAERLVRPVAARALEQGSLEQSSL 359 Query 214 PGVILRLMLAWIPSTGVPLLAIVLAVAADKIALLHATPEALFNPILMMALAALGIGSVST 273 + RLM W+ + VP+L I+L + A + E L ++ +A AL G + Sbjct 360 SPMSTRLMATWVLTNAVPVLGILLLIFAQARNFFDGSMEDLIPALVALAATALLTGFLGA 419 Query 274 LLVAMSIADPLRQLRWALSEVQRGNYNAHMQIYDASELGLLQAGFNDMVRELSERQRLRD 333 L AMS+ DP+R+L++A+++V+RGN ++IYD+SE+G++QAGFN+M+R L ERQ++ D Sbjct 420 RLSAMSVVDPVRELQFAINQVRRGNLETTVRIYDSSEIGVVQAGFNEMMRGLQERQQVSD 479 Query 334 LFGRYVGEDVARRALERGTELGGQERDVAVLFVDLVGSTQLAATRPPAEVVQLLNEFFRV 393 LFGRYVG +VARRALE ELGG+ RDVAVLFVD++GST A R P VV LNEFF Sbjct 480 LFGRYVGTEVARRALEEDPELGGESRDVAVLFVDVIGSTGFATQRSPEHVVSALNEFFDR 539 Query 394 VVETVARHGGFVNKFQGDAALAIFGAPIEHPDGAGAALSAARELHDELIPVLGSAEFGIG 453 VVE V H G +NKFQGDAALA+FGAP+ D AG AL+AARE+H +L + E G+G Sbjct 540 VVEVVHEHKGIINKFQGDAALAVFGAPLPLEDAAGHALAAAREMHSKLTDL--EFEAGVG 597 Query 454 VSAGRAIAGHIGAQARFEYTVIGDPVNEAARLTELAKLEDGHVLASAIAVSGALDAEALC 513 V+AG +AGHIGA+ RFEYTVIGD VN+A+RLT+LAK G VL SA V A +AE Sbjct 598 VAAGSVVAGHIGAKDRFEYTVIGDAVNQASRLTDLAKDTPGRVLTSAATVRLANEAEQRR 657 Query 514 WDVGEVVELRGRAAPTQLARPM 535 W + + VELRGR TQLARP+ Sbjct 658 WTMLKSVELRGRRQMTQLARPV 679 >gi|227549699|ref|ZP_03979748.1| adenylate cyclase [Corynebacterium lipophiloflavum DSM 44291] gi|227078195|gb|EEI16158.1| adenylate cyclase [Corynebacterium lipophiloflavum DSM 44291] Length=508 Score = 389 bits (1000), Expect = 5e-106, Method: Compositional matrix adjust. Identities = 208/506 (42%), Positives = 307/506 (61%), Gaps = 8/506 (1%) Query 30 RIHAFVRWVVRTPWPLFSLSMLQSDIIGALFVLGFLRYGLPPQDNIQLQDLPPVNLLIFV 89 RI +W+ T WPL++L++L ++++G + ++ F+RY +P + QL ++ + Sbjct 3 RIWRGFKWLWGTSWPLYALTVLGTNVLGGIAIMTFIRYFIPMAEVEQLSMTGGGLGVLGI 62 Query 90 STVIILFLAGAVVNLKLLMPVFRWQRRDNLLTEPDPAATELARSRALRMPLYRTLISLAV 149 + L G VV L PV WQR P+ + R+ LR+P+ +T+I + V Sbjct 63 AYAAFAVLVGVVVTFFLFRPVLEWQR------APEGHDPNMVRNLVLRIPMLQTVIVVGV 116 Query 150 WATGGGVFILASWSVAKHAAPVVAVATALGATATAIIGYLQSERVLRPVAVAALRSGVPE 209 W G + +A+ + VV ++T + A++ Y+Q+ R++RP+A +AL + Sbjct 117 WLIGIAIATIATSRIDARLTIVVLISTLMACLVVALLTYVQAARLVRPIAASALARRFED 176 Query 210 NVNAPGVILRLMLAWIPSTGVPLLAIVLAVAADKIALLHATPEALFNPILMMALAALGIG 269 + P + RL + W +T +PL+ I+L V A + TP L + ++L AL G Sbjct 177 STLEPPIKTRLYMTWFTTTAIPLIGILLLVWAQRSGFFTNTPGELMPAVSALSLTALATG 236 Query 270 SVSTLLVAMSIADPLRQLRWALSEVQRGNYNAHMQIYDASELGLLQAGFNDMVRELSERQ 329 S+ T+ M + DP+++L+ A++ V+RG + + IYD SE+G+LQAGFN+M+R L+ERQ Sbjct 237 SIGTIFAIMGVVDPIKELQEAINRVRRGESDTQVDIYDGSEIGVLQAGFNEMMRGLNERQ 296 Query 330 RLRDLFGRYVGEDVARRALERGTELGGQERDVAVLFVDLVGSTQLAATRPPAEVVQLLNE 389 R+RD+FGRYVG +VA+RALE ELGG++R AV+FVD++GST A P EVV LNE Sbjct 297 RVRDIFGRYVGSEVAQRALEEKPELGGEDRKAAVVFVDVIGSTTFAVNHSPEEVVAALNE 356 Query 390 FFRVVVETVARHGGFVNKFQGDAALAIFGAPIEHPDGAGAALSAARELHDELIPVLGSAE 449 FF +VVE V R+ G +NKFQGDAALA++GAP D AL AREL EL + + Sbjct 357 FFAIVVEVVHRNKGVINKFQGDAALAVYGAPTALHDATSHALQTARELRQELRGL--KLQ 414 Query 450 FGIGVSAGRAIAGHIGAQARFEYTVIGDPVNEAARLTELAKLEDGHVLASAIAVSGALDA 509 GIGV++G +AGHIG RFEYTVIGD VN AARLT+LAK G VL +A + A + Sbjct 415 AGIGVASGHVVAGHIGGSDRFEYTVIGDAVNAAARLTDLAKNSPGRVLTNAATLRAANEV 474 Query 510 EALCWDVGEVVELRGRAAPTQLARPM 535 E W + + +ELRGR TQLARP+ Sbjct 475 EQQRWTLMKSIELRGRNKMTQLARPV 500 >gi|229494635|ref|ZP_04388398.1| adenylate cyclase, family 3 [Rhodococcus erythropolis SK121] gi|229318997|gb|EEN84855.1| adenylate cyclase, family 3 [Rhodococcus erythropolis SK121] Length=492 Score = 389 bits (999), Expect = 7e-106, Method: Compositional matrix adjust. Identities = 235/490 (48%), Positives = 310/490 (64%), Gaps = 14/490 (2%) Query 48 LSMLQSDIIGALFVLGFLRYGLPPQDNIQLQDLPPVNLLIFVSTVIILFLAGAV---VNL 104 LSML +++IGA+ V F+RYG+P Q++ + N IF + L AGAV Sbjct 2 LSMLAANLIGAVLVFAFVRYGVPIQESDAIVADRVRNFAIFG---VYLAFAGAVSLTAAA 58 Query 105 KLLMPVFRWQRRDNLLTEPDPAATELARSRALRMPLYRTLISLAVWATGGGVFILASWSV 164 +L V RW+ R T + A AL PL + ++ L +W GG +F+ + + Sbjct 59 MMLKSVIRWRLRGGPPTRSEQMA-------ALHAPLRQAIVHLVLWILGGIIFVFLTITE 111 Query 165 AKHAAPVVAVATALGATATAIIGYLQSERVLRPVAVAALRSGVPENVNAPGVILRLMLAW 224 A V V + AT T Y+ ER+LRPVA AL G + APGV RL + W Sbjct 112 MPGLAIAVIVTVCMAATTTFGFTYMLGERILRPVAAQALSEGEFDRTMAPGVGTRLAMTW 171 Query 225 IPSTGVPLLAIVLAVAADKIALLHATPEALFNPILMMALAALGIGSVSTLLVAMSIADPL 284 T +P+ I+L + L +P++L IL++++ A+ ++L A I+DP+ Sbjct 172 GLGTLMPVAGIILLCSTQLTTDLEFSPDSLAWAILLISIMAIVQAFALSMLTATQISDPI 231 Query 285 RQLRWALSEVQRGNYNAHMQIYDASELGLLQAGFNDMVRELSERQRLRDLFGRYVGEDVA 344 RQLR A+ VQRG + ++++D SE+G LQ GFN M++E ER+ LR+LFG++VGEDVA Sbjct 232 RQLRRAIERVQRGATDVRVEVFDGSEIGRLQVGFNRMMKESDERRLLRELFGQHVGEDVA 291 Query 345 RRALERGTELGGQERDVAVLFVDLVGSTQLAATRPPAEVVQLLNEFFRVVVETVARHGGF 404 RRAL+ GTELGG+ R VAVLFVD+VGST AA RPP EVV+LLNEFFRVVV+ + RH GF Sbjct 292 RRALKFGTELGGETRFVAVLFVDMVGSTGAAAERPPGEVVELLNEFFRVVVDVIDRHHGF 351 Query 405 VNKFQGDAALAIFGAPIEHPDGAGAALSAARELHDELIPVLGSAEFGIGVSAGRAIAGHI 464 VNKF GDAALAIFGAP++ PD AAL+AAREL +L + G + GIGVSAG A+AG+I Sbjct 352 VNKFMGDAALAIFGAPLDRPDAPTAALAAARELRFKLNDITG-LDVGIGVSAGLAVAGNI 410 Query 465 GAQARFEYTVIGDPVNEAARLTELAKLEDGHVLASAIAVSGALDAEALCWDVGEVVELRG 524 GA RFEYTVIGDPVNEA+RLTELAKL VLAS A+ A + E W++GE V+LRG Sbjct 411 GAAERFEYTVIGDPVNEASRLTELAKLRPSRVLASTSALYFADEEEQAEWELGEQVQLRG 470 Query 525 RAAPTQLARP 534 R T LA P Sbjct 471 RRRLTHLAWP 480 >gi|296394982|ref|YP_003659866.1| adenylate/guanylate cyclase with integral membrane sensor [Segniliparus rotundus DSM 44985] gi|296182129|gb|ADG99035.1| adenylate/guanylate cyclase with integral membrane sensor [Segniliparus rotundus DSM 44985] Length=516 Score = 387 bits (995), Expect = 2e-105, Method: Compositional matrix adjust. Identities = 227/519 (44%), Positives = 321/519 (62%), Gaps = 13/519 (2%) Query 19 GLMATTAALPRRIHAFVRWVVRTPWPLFSLSMLQSDIIGALFVLGFLRYGLPPQDNIQLQ 78 G A PR I +RW+ RT WPL L ++ ++++GAL V GFL++GLPP+D + Sbjct 4 GRFAELGFTPRGILNLLRWLPRTRWPLIVLYVVYANVLGALIVFGFLQFGLPPEDAVSYT 63 Query 79 DLPPVNLLIFVSTVIILFLA-GAVVNLKLLMPVFRWQRRDNLLTEPDPAATELARSRALR 137 DL + ++ L +A ++VNL +P W + A + A+ RALR Sbjct 64 DLGDWRSQLLFLGLLSLGIAVSSMVNLGYAVPTLIWNH-----SREHSANAQRAKDRALR 118 Query 138 MPLYRTLISLAVWATGGGVFILASWSVAKHA---APVVAVATALGATATAIIGYLQSERV 194 +P ++ S ++W G VF+ +A+H+ A + A LG + +I YL+SE+V Sbjct 119 LPSWQMWTSGSLWLFGSLVFV---GFIARHSPRLALIGAFGAVLGGSVVCMIVYLRSEQV 175 Query 195 LRPVAVAALRSGVPENVNAPGVILRLMLAWIPSTGVPLLAIVLAVAADKIALLHATPEAL 254 LRP+ A+ G E A V R+ L W+ +G+P AI ++ +LH P+ L Sbjct 176 LRPIISEAIADGA-EAKRASKVSQRVQLVWLLCSGIPAFAIFGITTGHELGILHGNPKQL 234 Query 255 FNPILMMALAALGIGSVSTLLVAMSIADPLRQLRWALSEVQRGNYNAHMQIYDASELGLL 314 P+ ++A + +G ++ +A I P++ LR A+ +V++G+ +AH+++ +ELGLL Sbjct 235 MLPVSILAALTIAVGLLAANQLAKGIGVPIQALRGAMRQVEQGDLSAHVEVNTTTELGLL 294 Query 315 QAGFNDMVRELSERQRLRDLFGRYVGEDVARRALERGTELGGQERDVAVLFVDLVGSTQL 374 Q+GFNDM++++ R++LR LFG++VG +VA+RA+E G +LGG+ER VAVLFVDLVGST+L Sbjct 295 QSGFNDMIQQIRGREQLRALFGQFVGSEVAQRAVEDGVQLGGEERLVAVLFVDLVGSTRL 354 Query 375 AATRPPAEVVQLLNEFFRVVVETVARHGGFVNKFQGDAALAIFGAPIEHPDGAGAALSAA 434 A VV+LLNEFF VV+ V GG+VNKF GDAAL IFGAP+E + AG AL AA Sbjct 355 AFHLGAPRVVKLLNEFFHAVVDVVGAEGGYVNKFLGDAALVIFGAPLELENFAGHALRAA 414 Query 435 RELHDELIPVLGSAEFGIGVSAGRAIAGHIGAQARFEYTVIGDPVNEAARLTELAKLEDG 494 R LH+ L L GIGVSAG +AGHIGA R EYTVIGD VNEA+RL ELAKLE G Sbjct 415 RALHEVLAGPLHETNVGIGVSAGLVVAGHIGADERLEYTVIGDAVNEASRLCELAKLEPG 474 Query 495 HVLASAIAVSGALDAEALCWDVGEVVELRGRAAPTQLAR 533 +L S AV A EA W++GE V +RGR APT+LAR Sbjct 475 GLLTSERAVGLADPEEAQHWELGEEVCVRGREAPTRLAR 513 >gi|111022135|ref|YP_705107.1| adenylate cyclase [Rhodococcus jostii RHA1] gi|110821665|gb|ABG96949.1| possible adenylate cyclase [Rhodococcus jostii RHA1] Length=485 Score = 387 bits (995), Expect = 2e-105, Method: Compositional matrix adjust. Identities = 230/487 (48%), Positives = 305/487 (63%), Gaps = 8/487 (1%) Query 48 LSMLQSDIIGALFVLGFLRYGLPPQDNIQLQDLPPVNLLIFVSTVIILFLAGAVVNLKLL 107 +SML ++ IGA+ V F+RYG+P ++ ++ N+ IF + + +L Sbjct 2 VSMLLANFIGAILVFAFVRYGVPIPESQEIIADRVRNVAIFGGYLAFAAVVSLTAAAMML 61 Query 108 MPVFRWQRRDNLLTEPDPAATELARSRALRMPLYRTLISLAVWATGGGVFILASWSVAKH 167 V RWQ R P +E + AL PL + ++ L +W GG +F+L + + Sbjct 62 RSVVRWQLRGG-----PPTRSE--QMSALHAPLRQAIVHLVLWILGGIIFVLLTITEMPE 114 Query 168 AAPVVAVATALGATATAIIGYLQSERVLRPVAVAALRSGVPENVNAPGVILRLMLAWIPS 227 A V V + AT T Y+ ER+LRPVA AL G + APGV R+ + W Sbjct 115 LAVAVIVTVCMAATTTFGFTYMLGERILRPVAARALSEGEFDRTMAPGVGTRMAMTWGLG 174 Query 228 TGVPLLAIVLAVAADKIALLHATPEALFNPILMMALAALGIGSVSTLLVAMSIADPLRQL 287 T +P++ I+L L +P AL I+++++ A+ ++L A I+DP++QL Sbjct 175 TLMPVIGIILLCVTQITTDLVFSPNALAWAIMLLSIIAIAQAFALSMLTASQISDPIKQL 234 Query 288 RWALSEVQRGNYNAHMQIYDASELGLLQAGFNDMVRELSERQRLRDLFGRYVGEDVARRA 347 R A+ VQRG + ++++D SE+G LQ GFN M+RE ER+ LR+LFG++VGEDVARRA Sbjct 235 RRAIERVQRGATDVRVEVFDGSEIGRLQVGFNRMMRESDERRLLRELFGQHVGEDVARRA 294 Query 348 LERGTELGGQERDVAVLFVDLVGSTQLAATRPPAEVVQLLNEFFRVVVETVARHGGFVNK 407 L+ GTELGG+ R VAVLFVD+VGST AA RPP EVV LLNEFFRVVV+ + RH GFVNK Sbjct 295 LQFGTELGGETRFVAVLFVDMVGSTGAAAERPPGEVVNLLNEFFRVVVDVIDRHHGFVNK 354 Query 408 FQGDAALAIFGAPIEHPDGAGAALSAARELHDELIPVLGSAEFGIGVSAGRAIAGHIGAQ 467 F GDAALAIFGAP++ PD AAL+AAREL L + G + GIGVSAG A+AG+IGA Sbjct 355 FMGDAALAIFGAPLDRPDAPTAALAAARELRFALNEITG-LDVGIGVSAGLAVAGNIGAA 413 Query 468 ARFEYTVIGDPVNEAARLTELAKLEDGHVLASAIAVSGALDAEALCWDVGEVVELRGRAA 527 RFEYTVIGDPVNEA+RLTELAKL VLAS A+ A D E W++GE V+LRGR Sbjct 414 ERFEYTVIGDPVNEASRLTELAKLHPSRVLASTSALYFADDDEQAHWELGEQVQLRGRRR 473 Query 528 PTQLARP 534 T LA P Sbjct 474 NTHLAWP 480 >gi|300857644|ref|YP_003782627.1| adenylate cyclase [Corynebacterium pseudotuberculosis FRC41] gi|300685098|gb|ADK28020.1| adenylate cyclase [Corynebacterium pseudotuberculosis FRC41] Length=508 Score = 386 bits (992), Expect = 4e-105, Method: Compositional matrix adjust. Identities = 216/509 (43%), Positives = 313/509 (62%), Gaps = 9/509 (1%) Query 27 LPRRIHAFVRWVVRTPWPLFSLSMLQSDIIGALFVLGFLRYGLPPQDNIQLQDLPPVNLL 86 + R AF +W+ T WPL++ ++L S+++GA+ V+ FLRY +P + Sbjct 1 MTRMWRAF-KWLFGTSWPLYATTVLGSNVLGAVGVMLFLRYLVPLPEFAAFTKGTSYLPT 59 Query 87 IFVSTVIILFLAGAVVNLKLLMPVFRWQRRDNLLTEPDPAATELARSRALRMPLYRTLIS 146 + +S +++ G VV +L PV WQR P+ + R+ +R+P Y++ + Sbjct 60 LGISYLVVAVAFGIVVTFRLFRPVLDWQR------HPEIHDPNMVRNLVMRIPFYQSTLC 113 Query 147 LAVWATGGGVFILASWSVAKHAAPVVAVATALGATATAIIGYLQSERVLRPVAVAALRSG 206 VW G + +AS + + + VATAL + ++ YL++ER++RPVA AL Sbjct 114 ALVWLIGIVILAVASAQTSLRLSLAIIVATALSGSVVIVLTYLEAERLVRPVAATALARR 173 Query 207 VPENVNAPGVILRLMLAWIPSTGVPLLAIVLAVAADKIALLHATPEALFNPILMMALAAL 266 ++ P + RL L W+ ++ VP++ ++L +A L + +L ++L AL Sbjct 174 FEDSTLEPPIASRLRLTWLLTSAVPIVGVLLMIAGYYAGLFGNNIRDIIPAVLTLSLVAL 233 Query 267 GIGSVSTLLVAMSIADPLRQLRWALSEVQRGNYNAHMQIYDASELGLLQAGFNDMVRELS 326 G + T L MS+ DP+ +L+ A++ V+RG + + IYD SELG+LQAGFN+M+R L+ Sbjct 234 VTGFLGTTLSIMSVVDPILELQGAINRVRRGESDVQVDIYDGSELGVLQAGFNEMMRGLN 293 Query 327 ERQRLRDLFGRYVGEDVARRALERGTELGGQERDVAVLFVDLVGSTQLAATRPPAEVVQL 386 ERQR+RD+FGRYVG +VARRALE +LGG++R+VAV+FVD++GST A P EVV Sbjct 294 ERQRVRDIFGRYVGTEVARRALEEKPQLGGEDREVAVIFVDVIGSTTFAVNHDPEEVVAE 353 Query 387 LNEFFRVVVETVARHGGFVNKFQGDAALAIFGAPIEHPDGAGAALSAARELHDELIPVLG 446 LN+FF VV V R+ G +NKFQGDAALA+FGAPI D G AL+AAREL EL + Sbjct 354 LNKFFEHVVGVVHRNKGSINKFQGDAALAVFGAPITLSDATGHALTAARELRQELSGL-- 411 Query 447 SAEFGIGVSAGRAIAGHIGAQARFEYTVIGDPVNEAARLTELAKLEDGHVLASAIAVSGA 506 E GIGV++G +AG+IG RFEYTVIGD VN AARLTE+AK G VL +A + A Sbjct 412 RLEAGIGVASGHVVAGNIGGLDRFEYTVIGDAVNTAARLTEIAKNTPGRVLTNAATLKKA 471 Query 507 LDAEALCWDVGEVVELRGRAAPTQLARPM 535 +AE W + + VELRGR+ TQLARP+ Sbjct 472 NEAEQARWTLMKSVELRGRSMMTQLARPI 500 >gi|255324203|ref|ZP_05365325.1| adenylate cyclase, family 3 [Corynebacterium tuberculostearicum SK141] gi|255298719|gb|EET78014.1| adenylate cyclase, family 3 [Corynebacterium tuberculostearicum SK141] Length=510 Score = 386 bits (992), Expect = 4e-105, Method: Compositional matrix adjust. Identities = 230/513 (45%), Positives = 318/513 (62%), Gaps = 16/513 (3%) Query 36 RWVVRTPWPLFSLSMLQSDIIGALFVLGFLRYGLP-PQDNIQLQDLPPVNLLIFVSTVII 94 RW++ T WP+++ +L +++IGA+ ++ F+ Y LP P+ +LP L+ V+ V + Sbjct 9 RWLMGTQWPVYAALVLGANLIGAIAIMTFVLYFLPMPEIKDFAAELPS---LMGVAAVYL 65 Query 95 LF--LAGAVVNLKLLMPVFRWQRRDNLLTEPDPAATELARSRALRMPLYRTLISLAVWAT 152 +F + G V L L PV WQR PD + R+ LR+P+Y++ ++ AVW Sbjct 66 IFAVVIGIAVTLLLFRPVLDWQR------NPDEHDPNMVRNLVLRIPVYQSAVAAAVWLI 119 Query 153 GGGVFILASWSVAKHAAPVVAVATALGATATAIIGYLQSERVLRPVAVAALRSGVPENVN 212 G + ++ S + VV V+ L I+ YLQ+ER++RPVA A+ + Sbjct 120 GIILAVVISGRESGSLGLVVGVSATLAGLVVVILTYLQAERLVRPVAAQAVARRFEDATL 179 Query 213 APGVILRLMLAWIPSTGVPLLAIVLAVAADKIALLHATPEALFNPILMMALAALGIGSVS 272 P + RL+ W+ ++GVPL+ I+L + A + L T L I +AL AL G + Sbjct 180 EPPIKYRLISTWLMTSGVPLVGILLVLIAQRTGLFSGTAGDLVPAITALALTALATGFIG 239 Query 273 TLLVAMSIADPLRQLRWALSEVQRGNYNAHMQIYDASELGLLQAGFNDMVRELSERQRLR 332 T MS+ DP+ +L+ A++ V+RG +A + IYD SELG+LQAGFN+M+R L ERQR+R Sbjct 240 TSFAVMSVVDPIVELQDAINRVRRGENDAEVDIYDGSELGVLQAGFNEMMRGLRERQRVR 299 Query 333 DLFGRYVGEDVARRALERGTELGGQERDVAVLFVDLVGSTQLAATRPPAEVVQLLNEFFR 392 D+FGRYVG +VA+RALE ELGG++R VAVLF+D++GST A P EVV+ LN+FF Sbjct 300 DIFGRYVGVEVAQRALEERPELGGEDRKVAVLFIDVIGSTTFAVNHSPEEVVEELNKFFE 359 Query 393 VVVETVARHGGFVNKFQGDAALAIFGAPIEHPDGAGAALSAARELHDELIPVLGSAEFGI 452 VVE V R+ G +NKFQGDAALA+FGAP+ D A AL AAREL EL + + GI Sbjct 360 HVVEVVHRNKGIINKFQGDAALAVFGAPLNVYDSASMALQAARELRGELRGL--ELQAGI 417 Query 453 GVSAGRAIAGHIGAQARFEYTVIGDPVNEAARLTELAKLEDGHVLASAIAVSGALDAEAL 512 GV+AG +AGHIG RFEYTVIGD VNEAARLTELAK G VL +A + A +AE Sbjct 418 GVAAGHVVAGHIGGADRFEYTVIGDAVNEAARLTELAKDTPGQVLTNAATLKTANEAEQA 477 Query 513 CWDVGEVVELRGRAAPTQLARPM--NLAAPEEV 543 W + + +ELRGR TQLARP+ LA EV Sbjct 478 RWTMMKSIELRGRHRMTQLARPIRATLAERSEV 510 >gi|302205382|gb|ADL09724.1| Adenylate cyclase [Corynebacterium pseudotuberculosis C231] gi|302329936|gb|ADL20130.1| Adenylate cyclase [Corynebacterium pseudotuberculosis 1002] gi|308275620|gb|ADO25519.1| Putative adenylate cyclase [Corynebacterium pseudotuberculosis I19] gi|341824047|gb|AEK91568.1| Adenylate cyclase [Corynebacterium pseudotuberculosis PAT10] Length=505 Score = 386 bits (992), Expect = 4e-105, Method: Compositional matrix adjust. Identities = 213/500 (43%), Positives = 309/500 (62%), Gaps = 8/500 (1%) Query 36 RWVVRTPWPLFSLSMLQSDIIGALFVLGFLRYGLPPQDNIQLQDLPPVNLLIFVSTVIIL 95 +W+ T WPL++ ++L S+++GA+ V+ FLRY +P + + +S +++ Sbjct 6 KWLFGTSWPLYATTVLGSNVLGAVGVMLFLRYLVPLPEFAAFTKGTSYLPTLGISYLVVA 65 Query 96 FLAGAVVNLKLLMPVFRWQRRDNLLTEPDPAATELARSRALRMPLYRTLISLAVWATGGG 155 G VV +L PV WQR P+ + R+ +R+P Y++ + VW G Sbjct 66 VAFGIVVTFRLFRPVLDWQR------HPEIHDPNMVRNLVMRIPFYQSTLCALVWLIGIV 119 Query 156 VFILASWSVAKHAAPVVAVATALGATATAIIGYLQSERVLRPVAVAALRSGVPENVNAPG 215 + +AS + + + VATAL + ++ YL++ER++RPVA AL ++ P Sbjct 120 ILAVASAQTSLRLSLAIIVATALSGSVVIVLTYLEAERLVRPVAATALARRFEDSTLEPP 179 Query 216 VILRLMLAWIPSTGVPLLAIVLAVAADKIALLHATPEALFNPILMMALAALGIGSVSTLL 275 + RL L W+ ++ VP++ ++L +A L + +L ++L AL G + T L Sbjct 180 IASRLRLTWLLTSAVPIVGVLLMIAGYYAGLFGNNIRDIIPAVLTLSLVALVTGFLGTTL 239 Query 276 VAMSIADPLRQLRWALSEVQRGNYNAHMQIYDASELGLLQAGFNDMVRELSERQRLRDLF 335 MS+ DP+ +L+ A++ V+RG + + IYD SELG+LQAGFN+M+R L+ERQR+RD+F Sbjct 240 SIMSVVDPILELQGAINRVRRGESDVQVDIYDGSELGVLQAGFNEMMRGLNERQRVRDIF 299 Query 336 GRYVGEDVARRALERGTELGGQERDVAVLFVDLVGSTQLAATRPPAEVVQLLNEFFRVVV 395 GRYVG +VARRALE +LGG++R+VAV+FVD++GST A P EVV LN+FF VV Sbjct 300 GRYVGTEVARRALEEKPQLGGEDREVAVIFVDVIGSTTFAVNHDPEEVVAELNKFFEHVV 359 Query 396 ETVARHGGFVNKFQGDAALAIFGAPIEHPDGAGAALSAARELHDELIPVLGSAEFGIGVS 455 V R+ G +NKFQGDAALA+FGAPI D G AL+AAREL EL + E GIGV+ Sbjct 360 GVVHRNKGSINKFQGDAALAVFGAPITLSDATGHALTAARELRQELSGL--RLEAGIGVA 417 Query 456 AGRAIAGHIGAQARFEYTVIGDPVNEAARLTELAKLEDGHVLASAIAVSGALDAEALCWD 515 +G +AG+IG RFEYTVIGD VN AARLTE+AK G VL +A + A +AE W Sbjct 418 SGHVVAGNIGGLDRFEYTVIGDAVNTAARLTEIAKNTPGRVLTNAATLKKANEAEQARWT 477 Query 516 VGEVVELRGRAAPTQLARPM 535 + + VELRGR+ TQLARP+ Sbjct 478 LMKSVELRGRSMMTQLARPI 497 >gi|337289888|ref|YP_004628909.1| adenylate cyclase [Corynebacterium ulcerans BR-AD22] gi|334696014|gb|AEG80811.1| adenylate cyclase [Corynebacterium ulcerans 809] gi|334698194|gb|AEG82990.1| adenylate cyclase [Corynebacterium ulcerans BR-AD22] Length=508 Score = 386 bits (992), Expect = 5e-105, Method: Compositional matrix adjust. Identities = 212/500 (43%), Positives = 304/500 (61%), Gaps = 8/500 (1%) Query 36 RWVVRTPWPLFSLSMLQSDIIGALFVLGFLRYGLPPQDNIQLQDLPPVNLLIFVSTVIIL 95 +W+ T WPL++ ++L S+++GA+ V+ FLRY +P + + +S +++ Sbjct 9 KWLFGTSWPLYATTVLGSNVLGAVGVMLFLRYLVPMPEFAAFTKGTSYLPTLGISYLVVA 68 Query 96 FLAGAVVNLKLLMPVFRWQRRDNLLTEPDPAATELARSRALRMPLYRTLISLAVWATGGG 155 G VV +L PV WQR PD + R+ +R+P Y++ + VW G Sbjct 69 VAFGIVVTFRLFRPVLDWQR------HPDIHDPNMVRNLVMRIPFYQSALCALVWLIGIV 122 Query 156 VFILASWSVAKHAAPVVAVATALGATATAIIGYLQSERVLRPVAVAALRSGVPENVNAPG 215 + +AS + A + VAT L + ++ YL++ER++RPVA AL ++ P Sbjct 123 ILAVASAQTSPRLALAIVVATTLSGSVVIVLTYLEAERLVRPVAATALARRFEDSTLEPP 182 Query 216 VILRLMLAWIPSTGVPLLAIVLAVAADKIALLHATPEALFNPILMMALAALGIGSVSTLL 275 + RL L W+ ++ VP+ ++L + + +L ++L +L G + T L Sbjct 183 IASRLRLTWLLTSAVPIFGVILMIVGYHAGFFGHNIRDIIPAVLTLSLVSLVTGFLGTTL 242 Query 276 VAMSIADPLRQLRWALSEVQRGNYNAHMQIYDASELGLLQAGFNDMVRELSERQRLRDLF 335 MS+ DP+ +L+ A++ V+RG + + IYD SELG+LQAGFN+M+R L ERQR+RD+F Sbjct 243 SIMSVVDPILELQGAINRVRRGESDVQVDIYDGSELGVLQAGFNEMMRGLKERQRVRDIF 302 Query 336 GRYVGEDVARRALERGTELGGQERDVAVLFVDLVGSTQLAATRPPAEVVQLLNEFFRVVV 395 GRYVG +VARRALE +LGG++R+VAV+FVD++GST A P EVV LN+FF VV Sbjct 303 GRYVGAEVARRALEEKPQLGGEDREVAVVFVDVIGSTTFAVNHGPEEVVAELNKFFEHVV 362 Query 396 ETVARHGGFVNKFQGDAALAIFGAPIEHPDGAGAALSAARELHDELIPVLGSAEFGIGVS 455 V R+ G +NKFQGDAALA+FGAPI D G AL+AAREL EL + E GIGV+ Sbjct 363 GVVHRNKGIINKFQGDAALAVFGAPITLSDATGHALAAARELRQELSGL--RLEAGIGVA 420 Query 456 AGRAIAGHIGAQARFEYTVIGDPVNEAARLTELAKLEDGHVLASAIAVSGALDAEALCWD 515 +G +AGHIG RFEYTVIGD VN AARLTE+AK G VL +A + A +AE W Sbjct 421 SGHVVAGHIGGLDRFEYTVIGDAVNTAARLTEIAKDTPGRVLTNAATLKKANEAEQGRWT 480 Query 516 VGEVVELRGRAAPTQLARPM 535 + + VELRGR+ TQLARP+ Sbjct 481 LMKSVELRGRSMMTQLARPI 500 >gi|311741024|ref|ZP_07714849.1| probable adenylate cyclase [Corynebacterium pseudogenitalium ATCC 33035] gi|311303826|gb|EFQ79904.1| probable adenylate cyclase [Corynebacterium pseudogenitalium ATCC 33035] Length=510 Score = 386 bits (991), Expect = 6e-105, Method: Compositional matrix adjust. Identities = 229/513 (45%), Positives = 318/513 (62%), Gaps = 16/513 (3%) Query 36 RWVVRTPWPLFSLSMLQSDIIGALFVLGFLRYGLP-PQDNIQLQDLPPVNLLIFVSTVII 94 RW++ T WP+++ +L +++IGA+ ++ F+ Y LP P+ +LP L+ V+ V + Sbjct 9 RWLMGTQWPVYAALVLGANLIGAIAIMTFVLYFLPMPEIKDFAAELPS---LMGVAAVYL 65 Query 95 LF--LAGAVVNLKLLMPVFRWQRRDNLLTEPDPAATELARSRALRMPLYRTLISLAVWAT 152 +F + G V L L PV WQR PD + R+ LR+P+Y+++++ AVW Sbjct 66 IFAVVIGIAVTLLLFRPVLDWQR------NPDEHDPNMVRNLVLRIPVYQSVVAAAVWLI 119 Query 153 GGGVFILASWSVAKHAAPVVAVATALGATATAIIGYLQSERVLRPVAVAALRSGVPENVN 212 G + ++ S + VV V+ L I+ YLQ+ER++RPVA A+ + Sbjct 120 GIILAVVISGRESGSLGLVVGVSATLAGLVVVILTYLQAERLVRPVAAQAVARRFEDATL 179 Query 213 APGVILRLMLAWIPSTGVPLLAIVLAVAADKIALLHATPEALFNPILMMALAALGIGSVS 272 P + RL+ W+ ++ VPL+ I+L + A + L T L I +AL AL G + Sbjct 180 EPPIKYRLISTWLMTSAVPLVGILLVLIAQRTGLFSGTAGDLVPAITALALTALATGFIG 239 Query 273 TLLVAMSIADPLRQLRWALSEVQRGNYNAHMQIYDASELGLLQAGFNDMVRELSERQRLR 332 T MS+ DP+ +L+ A++ V+RG +A + IYD SELG+LQAGFN+M+R L ERQR+R Sbjct 240 TSFAVMSVVDPIVELQDAINRVRRGENDAEVDIYDGSELGVLQAGFNEMMRGLRERQRVR 299 Query 333 DLFGRYVGEDVARRALERGTELGGQERDVAVLFVDLVGSTQLAATRPPAEVVQLLNEFFR 392 D+FGRYVG +VA+RALE ELGG++R VAVLF+D++GST A P EVV+ LN+FF Sbjct 300 DIFGRYVGAEVAQRALEERPELGGEDRKVAVLFIDVIGSTTFAVNHSPEEVVEELNKFFE 359 Query 393 VVVETVARHGGFVNKFQGDAALAIFGAPIEHPDGAGAALSAARELHDELIPVLGSAEFGI 452 VVE V R+ G +NKFQGDAALA+FGAP+ D A AL AAREL EL + + GI Sbjct 360 HVVEVVHRNKGIINKFQGDAALAVFGAPLNVYDSASMALQAARELRGELRGL--ELQAGI 417 Query 453 GVSAGRAIAGHIGAQARFEYTVIGDPVNEAARLTELAKLEDGHVLASAIAVSGALDAEAL 512 GV+AG +AGHIG RFEYTVIGD VNEAARLTELAK G VL +A + A +AE Sbjct 418 GVAAGHVVAGHIGGADRFEYTVIGDAVNEAARLTELAKDTPGQVLTNAATLKTANEAEQA 477 Query 513 CWDVGEVVELRGRAAPTQLARPM--NLAAPEEV 543 W + + +ELRGR TQLARP+ LA EV Sbjct 478 RWTMMKSIELRGRHRMTQLARPIRATLAERSEV 510 >gi|259506071|ref|ZP_05748973.1| adenylate cyclase [Corynebacterium efficiens YS-314] gi|259166359|gb|EEW50913.1| adenylate cyclase [Corynebacterium efficiens YS-314] Length=508 Score = 385 bits (990), Expect = 9e-105, Method: Compositional matrix adjust. Identities = 215/508 (43%), Positives = 311/508 (62%), Gaps = 12/508 (2%) Query 30 RIHAFVRWVVRTPWPLFSLSMLQSDIIGALFVLGFLRYGLPPQDNIQLQDLPPVNLLIFV 89 R+ ++W+ T WPL++ ++L ++++GAL ++ F+RY +P ++ L V Sbjct 3 RLLQALKWLWGTSWPLYAATVLGTNVLGALAIMLFVRYLIPHPTEASFDS--DISYLPVV 60 Query 90 STVIILF--LAGAVVNLKLLMPVFRWQRRDNLLTEPDPAATELARSRALRMPLYRTLISL 147 V ++F L G +V + PV WQR PD + R+ +R+P+Y+ ++ Sbjct 61 GGVYLVFAVLVGILVTFLMFRPVLDWQR------HPDEHDPNMVRNLVMRIPIYQAILCA 114 Query 148 AVWATGGGVFILASWSVAKHAAPVVAVATALGATATAIIGYLQSERVLRPVAVAALRSGV 207 VW G + + +++ A +V V+T L +++ +L++ER++RPVA AL Sbjct 115 VVWFIGIIIATAIAATMSTPLAVIVFVSTMLACAVVSLLTFLEAERLVRPVAATALARRY 174 Query 208 PENVNAPGVILRLMLAWIPSTGVPLLAIVLAVAADKIALLHATPEALFNPILMMALAALG 267 ++ P V RL + W+ + GVP+L I+L + + + I+ +ALAA+ Sbjct 175 EDSTLEPPVSQRLRMTWVLTIGVPVLGILLMILGYNSGIFGDDASVILPAIISLALAAMV 234 Query 268 IGSVSTLLVAMSIADPLRQLRWALSEVQRGNYNAHMQIYDASELGLLQAGFNDMVRELSE 327 G T L S+ DP+ +L+ A+ V+RG+ + + IYD SE+G+LQAGFN+M+R L E Sbjct 235 TGYFGTSLAVASVVDPILELQDAIGRVRRGDNDVQVDIYDGSEIGVLQAGFNEMMRGLRE 294 Query 328 RQRLRDLFGRYVGEDVARRALERGTELGGQERDVAVLFVDLVGSTQLAATRPPAEVVQLL 387 RQR+RDLFGRYVG++VARRALE LGG++R VAVLFVD++GST A P EVV+ L Sbjct 295 RQRVRDLFGRYVGDEVARRALEERPTLGGEDRKVAVLFVDVIGSTTFAVNHAPEEVVEAL 354 Query 388 NEFFRVVVETVARHGGFVNKFQGDAALAIFGAPIEHPDGAGAALSAARELHDELIPVLGS 447 NEFF VVE + R+ G +NKFQGDAALAIFGAP+ D G AL+AAREL EL + Sbjct 355 NEFFERVVEVIHRNKGVINKFQGDAALAIFGAPLPLSDATGHALAAARELRIELKDLQLK 414 Query 448 AEFGIGVSAGRAIAGHIGAQARFEYTVIGDPVNEAARLTELAKLEDGHVLASAIAVSGAL 507 A GIGV+AG +AGHIG RFEYTVIGD VN+AARLTE+AK G + +A + A Sbjct 415 A--GIGVAAGHVVAGHIGGHDRFEYTVIGDAVNQAARLTEIAKTTPGRTVTNAATLREAN 472 Query 508 DAEALCWDVGEVVELRGRAAPTQLARPM 535 +AE W + + VELRGR TQLARP+ Sbjct 473 EAEQARWTLMKSVELRGRGEMTQLARPI 500 >gi|68537046|ref|YP_251751.1| adenylate cyclase, putative [Corynebacterium jeikeium K411] gi|68264645|emb|CAI38133.1| adenylate cyclase, putative [Corynebacterium jeikeium K411] Length=510 Score = 385 bits (990), Expect = 9e-105, Method: Compositional matrix adjust. Identities = 220/510 (44%), Positives = 315/510 (62%), Gaps = 14/510 (2%) Query 29 RRIHAFVRWVVRTPWPLFSLSMLQSDIIGALFVLGFLRY--GLPPQDNIQLQDLPPVNL- 85 +++ ++ W T WPL++ ++L +++IGA V FLR+ LP + D +L Sbjct 2 KQLLRYLSWAWGTSWPLYAATVLATNVIGATAVATFLRFLIPLPAARELTSPDTTIASLY 61 Query 86 LIFVSTVIILFLAGAVVNLKLLMPVFRWQRRDNLLTEPDPAATELARSRALRMPLYRTLI 145 LI+ ++ AG + L PV RWQR P + R LR+PL +T+ Sbjct 62 LIYFGVAVV---AGIAMTLYFFAPVLRWQR------TPQAYDPNMVRDLVLRIPLLQTVT 112 Query 146 SLAVWATGGGVFILASWSVAKHAAPVVAVATALGATATAIIGYLQSERVLRPVAVAALRS 205 + +W G +F + +W + V V LG +++ Y+++ER++RPVA AL Sbjct 113 GIVLWGIGVVLFTVVAWRHSTEWGITVGVTATLGGMMVSLMTYMEAERLVRPVAAKALAK 172 Query 206 GVPENVNAPGVILRLMLAWIPSTGVPLLAIVLAVAADKIALLHATPEALFNPILMMALAA 265 G P++ + RLM W ++ VP+L +VL + A + + +L +AL Sbjct 173 GAPDHSRLSPLSHRLMTTWALTSAVPVLGMVLLLFAAATEFYPESSRGIIPAMLALALTT 232 Query 266 LGIGSVSTLLVAMSIADPLRQLRWALSEVQRGNYNAHMQIYDASELGLLQAGFNDMVREL 325 L G + T L +M++ADP+R+L++A++ V+RG N ++IYD+SE+G+LQAGFN+M+R L Sbjct 233 LLTGFMGTTLFSMAVADPIRELQYAINRVRRGKVNTDVRIYDSSEIGVLQAGFNEMMRGL 292 Query 326 SERQRLRDLFGRYVGEDVARRALERGTELGGQERDVAVLFVDLVGSTQLAATRPPAEVVQ 385 ERQR+ DLFGRYVG +VARRALE ELGG+ R VAVLFVD++GST A + P VV+ Sbjct 293 QERQRVSDLFGRYVGTEVARRALEEKPELGGETRHVAVLFVDVIGSTGFATEKEPQHVVK 352 Query 386 LLNEFFRVVVETVARHGGFVNKFQGDAALAIFGAPIEHPDGAGAALSAARELHDELIPVL 445 LNEFF VVE V + G +NKF+GDAALA+FGAP+ D AG AL+AAREL +L + Sbjct 353 ALNEFFDRVVEVVHANKGIINKFEGDAALAVFGAPLPLDDVAGHALAAARELKAKLQGLE 412 Query 446 GSAEFGIGVSAGRAIAGHIGAQARFEYTVIGDPVNEAARLTELAKLEDGHVLASAIAVSG 505 +A G+GV+AG +AGHIGA+ RFEYTVIGD VN+AARLT+LAK G VL SA + Sbjct 413 FAA--GVGVAAGSVVAGHIGAKDRFEYTVIGDAVNQAARLTDLAKKTPGQVLTSAATLRA 470 Query 506 ALDAEALCWDVGEVVELRGRAAPTQLARPM 535 A +AE W + + VELRGR TQ+ARP+ Sbjct 471 ANEAEQARWTMMKSVELRGRREMTQIARPI 500 >gi|25026866|ref|NP_736920.1| hypothetical protein CE0310 [Corynebacterium efficiens YS-314] gi|23492146|dbj|BAC17120.1| conserved hypothetical protein [Corynebacterium efficiens YS-314] Length=538 Score = 385 bits (989), Expect = 1e-104, Method: Compositional matrix adjust. Identities = 215/508 (43%), Positives = 311/508 (62%), Gaps = 12/508 (2%) Query 30 RIHAFVRWVVRTPWPLFSLSMLQSDIIGALFVLGFLRYGLPPQDNIQLQDLPPVNLLIFV 89 R+ ++W+ T WPL++ ++L ++++GAL ++ F+RY +P ++ L V Sbjct 33 RLLQALKWLWGTSWPLYAATVLGTNVLGALAIMLFVRYLIPHPTEASFDS--DISYLPVV 90 Query 90 STVIILF--LAGAVVNLKLLMPVFRWQRRDNLLTEPDPAATELARSRALRMPLYRTLISL 147 V ++F L G +V + PV WQR PD + R+ +R+P+Y+ ++ Sbjct 91 GGVYLVFAVLVGILVTFLMFRPVLDWQR------HPDEHDPNMVRNLVMRIPIYQAILCA 144 Query 148 AVWATGGGVFILASWSVAKHAAPVVAVATALGATATAIIGYLQSERVLRPVAVAALRSGV 207 VW G + + +++ A +V V+T L +++ +L++ER++RPVA AL Sbjct 145 VVWFIGIIIATAIAATMSTPLAVIVFVSTMLACAVVSLLTFLEAERLVRPVAATALARRY 204 Query 208 PENVNAPGVILRLMLAWIPSTGVPLLAIVLAVAADKIALLHATPEALFNPILMMALAALG 267 ++ P V RL + W+ + GVP+L I+L + + + I+ +ALAA+ Sbjct 205 EDSTLEPPVSQRLRMTWVLTIGVPVLGILLMILGYNSGIFGDDASVILPAIISLALAAMV 264 Query 268 IGSVSTLLVAMSIADPLRQLRWALSEVQRGNYNAHMQIYDASELGLLQAGFNDMVRELSE 327 G T L S+ DP+ +L+ A+ V+RG+ + + IYD SE+G+LQAGFN+M+R L E Sbjct 265 TGYFGTSLAVASVVDPILELQDAIGRVRRGDNDVQVDIYDGSEIGVLQAGFNEMMRGLRE 324 Query 328 RQRLRDLFGRYVGEDVARRALERGTELGGQERDVAVLFVDLVGSTQLAATRPPAEVVQLL 387 RQR+RDLFGRYVG++VARRALE LGG++R VAVLFVD++GST A P EVV+ L Sbjct 325 RQRVRDLFGRYVGDEVARRALEERPTLGGEDRKVAVLFVDVIGSTTFAVNHAPEEVVEAL 384 Query 388 NEFFRVVVETVARHGGFVNKFQGDAALAIFGAPIEHPDGAGAALSAARELHDELIPVLGS 447 NEFF VVE + R+ G +NKFQGDAALAIFGAP+ D G AL+AAREL EL + Sbjct 385 NEFFERVVEVIHRNKGVINKFQGDAALAIFGAPLPLSDATGHALAAARELRIELKDLQLK 444 Query 448 AEFGIGVSAGRAIAGHIGAQARFEYTVIGDPVNEAARLTELAKLEDGHVLASAIAVSGAL 507 A GIGV+AG +AGHIG RFEYTVIGD VN+AARLTE+AK G + +A + A Sbjct 445 A--GIGVAAGHVVAGHIGGHDRFEYTVIGDAVNQAARLTEIAKTTPGRTVTNAATLREAN 502 Query 508 DAEALCWDVGEVVELRGRAAPTQLARPM 535 +AE W + + VELRGR TQLARP+ Sbjct 503 EAEQARWTLMKSVELRGRGEMTQLARPI 530 Lambda K H 0.323 0.137 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 1216677624312 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40